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1

Incidence of cardiovascular diseases and associated risk factors among subjects with type 2 diabetes – An 11-year follow up study  

PubMed Central

Aims This study was planned to assess the development of cardiovascular disease (CVD) events over an 11-year period and to identify the associated risk factors that could predict the onset of CVD among subjects with type 2 diabetes. Methods Retrospective data of 249 patients (M:F 149:100) with type 2 diabetes, from a cohort of 7800 patients, attending a tertiary care center for diabetes from January 2000 to December 2011 were retrieved and analyzed for this study. Sociodemographic and habitual risk factors, baseline diabetes duration, HbA1c and time of onset of CVD and its risk factors were collected from case records. Person-years method was used to calculate incident rate of CVD. Binary logistic regression analyses were done to identify predictors associated with CVD and its risk factors. Results Incidence of CVD among subjects with diabetes was 5.6 cases/1000 person-years. Nearly 60% developed hypertension and dyslipidemia or both during the 11-year period. The most common complication was neuropathy (14.4%). Smoking [OR (95%CI)] [9.26 (1.6–54.9)] (p = 0.014) and heavy alcohol consumption [8.7 (1.1–69.8)] (p = 0.04) were significantly associated with CVD. Higher BMI was significantly associated with hypertension and dyslipidemia [2.4 (1.3–4.3)] (p = 0.003). Conclusions Smoking and heavy alcohol consumption were significantly associated with CVD, and increased BMI was significantly associated with hypertension and dyslipidemia among subjects with type 2 diabetes in this study population. These findings emphasize the need for early identification and modification of risk factors associated with CVD events in patients with diabetes. PMID:24581089

Umamahesh, K.; Vigneswari, A.; Surya Thejaswi, G.; Satyavani, K.; Viswanathan, Vijay

2014-01-01

2

Incidence of and Factors for Self-reported Fragility Fractures Among Middle-aged and Elderly Women in Rural Korea: An 11-Year Follow-up Study  

PubMed Central

Objectives: This community-based cohort study was performed to investigate the incidence of and factors related to self-reported fragility fractures among middle-aged and elderly women living in rural Korea. Methods: The osteoporosis cohort recruited 430 women 40 to 69 years old in 1999, and 396 of these women were followed over 11 years. In 1999, questionnaires from all participants assessed general characteristics, medical history, lifestyle, menstrual and reproductive characteristics, and bone mineral density. In 2010, self-reported fractures and the date, site, and cause of these fractures were recorded. Cox proportional hazards models were used to calculate hazard ratios (HRs). Results: Seventy-six participants among 3949.7 person-years experienced fragility fractures during the 11-year follow-up. The incidence of fragility fractures was 1924.2 per 100 000 person-years (95% confidence interval [CI], 1491.6 to 2356.8). In the multivariate model, low body mass index (HR, 2.66; 95% CI, 1.13 to 6.24), a parental history of osteoporosis (HR, 2.03; 95% CI, 1.18 to 3.49), and postmenopausal status (HR, 3.50; 95% CI, 1.05 to 11.67) were significantly related to fragility fracture. Conclusions: Fracture prevention programs are needed among postmenopausal, rural, Korean women with a low body mass index and parental history of osteoporosis Korea. PMID:25274003

Ahn, Soon-Ki; Kam, Sin; Chun, Byung-Yeol

2014-01-01

3

Early Predictors of Language and Social Communication Impairments at Ages 9-11 Years: A Follow-up Study of Early-Referred Children  

ERIC Educational Resources Information Center

Purpose: In this study, the authors aimed to evaluate hypotheses that early sociocognition will predict later social communication and early phonology will predict later morphosyntax in clinically referred preschoolers. Method: Participants were 108 children ages 9-11 years who had been referred to clinical services with concerns about language at…

Chiat, Shula; Roy, Penny

2013-01-01

4

Intake of fat and fiber-rich foods according to socioeconomic status: the 11-year follow-up of the 1993 Pelotas (Brazil) birth cohort study  

PubMed Central

This study describes the food intake of adolescents participating in the 1993 birth cohort from Pelotas, Southern Brazil, according to socioeconomic position. We carried out a cross-sectional analysis of data collected in the 2004-2005 follow-up visit. Food intake in the previous year was evaluated using the Block questionnaire. Socioeconomic status was evaluated based on an assets index, divided into quintiles. Foods with the highest frequency of daily intake were white bread (83%), butter or margarine (74.6%), beans (66.4%) and milk (48.5%). Intake of butter or margarine, bread, and beans was more frequent among poorer adolescents, and the inverse was true for milk. Intake of fruits and vegetables was low in all socioeconomic strata, but particularly low among the poor. In early adolescence, all socioeconomic groups showed high consumption of foods rich in fat and low consumption of foods rich in fiber. PMID:20963287

Neutzling, Marilda B.; Araújo, Cora Luiza; Vieira, Maria de Fátima A.; Hallal, Pedro C.; Menezes, Ana M. B.; Victora, Cesar G.

2013-01-01

5

A Neurophysiological Marker of Impaired Preparation in an 11-Year Follow-Up Study of Attention-Deficit/Hyperactivity Disorder (ADHD)  

ERIC Educational Resources Information Center

Background: This longitudinal electrophysiological study investigated the course of multiple impaired cognitive brain functions in attention-deficit/hyperactivity disorder (ADHD) from childhood to adulthood by comparing developmental trajectories of individuals with ADHD and typically developing controls. Methods: Subjects with ADHD ("N"…

Doehnert, Mirko; Brandeis, Daniel; Schneider, Gudrun; Drechsler, Renate; Steinhausen, Hans-Christoph

2013-01-01

6

Midterm results with primary uncemented total hip replacement: a 7- to 11-year follow-up  

Microsoft Academic Search

We reviewed 102 uncemented total hip replacements (THRs) in 90 patients with a mean age of 66 years (range, 33–87 years)\\u000a and with an average postoperative follow-up period of 8.5 years (range, 7–11 years). The patients were prospectively observed\\u000a clinically using the Harris hip score (HHS). The excellent and good results totaled over 90%. We had two serious complications\\u000a treated

George Petrou; Anastasios Kouzoupis; Michael Gavras; Harris Petrou

2000-01-01

7

Life dissatisfaction and subsequent work disability in an 11-year follow-up  

Microsoft Academic Search

Background. Mental disorders are associated with disability, but the long-term effects of low sub- jective well-being on work ability in general population are not known. In this study we investigated whether self-reported life dissatisfaction predicts work disability. Method. A nationwide sample of Finnish twins aged 18-54 years (N=22 136), unselected for health status responded to a health questionnaire with a

H. KOIVUMAA-HONKANEN; M. KOSKENVUO; R. J. HONKANEN; H. VIINAMKI; K. HEIKKIL; J. KAPRIO

2004-01-01

8

Minimal 11-year follow-up of extensively porous-coated stems in femoral revision total hip arthroplasty  

Microsoft Academic Search

Between 1984 and 1989, 188 consecutive femoral revision surgeries were performed. Eighteen patients died or were lost to follow-up, and the remaining 170 patients were followed for 11 to 16 years (mean, 14.2 years). Radiographic evidence of a bone ingrown stem was present in 82% of the hips, stable fibrous fixation was present in 14% of the hips, and 4%

Steven H. Weeden; Wayne G. Paprosky

2002-01-01

9

Follow-up study of alcoholic hallucinosis.  

PubMed

Alcoholic hallucinosis is a pathological mental state characterized by an acute onset of predominant auditory hallucinations that occur either during or after a period of heavy alcohol consumption. In this study, 52 patients with a diagnosis of Psychotic disorder predominantly hallucinatory associated with alcohol use (F 10.52) were evaluated after a period of three years. Past history of withdrawal hallucinations was associated with alcoholic hallucinosis The study has found a wide spectrum of outcome confirming the earlier observations that alcoholic hallucinosis is a heterogeneous disorder. PMID:21206866

Perme, Bojir; Vijaysagar, Kommu John; Chandrasekharan, R

2003-10-01

10

Nursing Education Follow-up Study.  

ERIC Educational Resources Information Center

This report discusses a study made to obtain information that would improve the quality of the Bakersfield College nursing-education program and lead to a better match between supply and demand in the nursing labor market in the Bakersfield area. The five parts of the report are: 1. Methodology; 2. Results of Responses to Questionnaire Items; 3.…

Scott, David C.

11

Food Service Follow-up Study.  

ERIC Educational Resources Information Center

Bakersfield City College reports on a followup study done to evaluate their Food Service Management Program. The program offers courses in three areas: certification and skill updating for those already employed in school cafeteria work, an A.A. degree program, and avocational courses for extended day students. Identical questionnaires were sent…

Scott, David C.

12

Follow-Up Study: Early Intervention Program.  

ERIC Educational Resources Information Center

As part of the evaluation scheme of the University of South Florida's College of Education Early Intervention Program, a followup study was conducted with 25 graduates of the program (1970-73). Ss responses to a followup scale provided information on changes in their professional aspirations, development, and involvement and on their retrospective…

Singh, S. P.; Allen, Elaine S.

13

1978 Entrant Follow-Up Study.  

ERIC Educational Resources Information Center

In spring 1982, a study was conducted to evaluate the success of Harford Community College (HCC), Maryland, in assisting students in achieving their educational goals, in preparing for transfer to a four-year college or university, and in career development. A sample of 650 students, selected from the 1,155 students who enrolled at HCC for the…

Quinley, John W.

14

Graduate Follow-Up Studies: How Useful Are They?  

ERIC Educational Resources Information Center

Follow-up surveys may fall prey to several sources of bias and error, among them lack of control over independent variables, lack of item validity and reliability, sampling biases, and observation bias. Two follow-up studies have been dissected to expose inherent limitations: the Texas Education Product Study (TEPS) and Project TALENT. The…

Smedley, Rande H.; Olson, George H.

15

Prognosis in autism: A follow-up study  

Microsoft Academic Search

A follow-up study involving 85 autistic boys and 35 girls, c. 5 1\\/2 years of age at initial evaluation and 12 years at follow-up, is presented and discussed in considerable detail. Measures, also applied to 26 non-psychotic subnormal controls, included speech, social, educational, and family adequacy ratings, IQ's, and neurological data. Most autistic children remained educationally retarded and 42% were

Marian K. DeMyer; Sandra Barton; William E. DeMyer; James A. Norton; John Allen; Robert Steele

1973-01-01

16

FOLLOW UP STUDY OF CHILDREN WITH DEVELOPMENTAL DISABILITIES  

EPA Science Inventory

The Follow-Up Study involves locating and interviewing a group of young adults who, as 10-year-old children, were included in the Metropolitan Atlanta Developmental Disabilities Study, an investigation of the prevalence and risk factors for developmental disabilities that was con...

17

A Follow-Up Study of Former Student Health Advocates  

ERIC Educational Resources Information Center

Student health advocates (SHAs) are high school students who, under the supervision of the school nurse, provide health education and health promotion activities to other students via a peer education model. This 3-year follow-up study explored how the SHA experience influences career choice and attitudes of the participants. It also examined what…

Streng, Nancy J.

2007-01-01

18

Follow-Up Study of Pupils with Differing Preschool Experiences.  

ERIC Educational Resources Information Center

A follow-up study of the Early Childhood Education Project (ECEP) was conducted in Richmond, Virginia to determine the effects of preschool experiences on selected aspects of pupil performance at the beginning and completion of grade 1. EPEC is a Head Start type program organized for the regular school year. The sample was divided into three…

Turner, Robert V.; DeFord, Edward F.

19

Undifferentiated Spondyloarthropathies: A 2Year Follow-up Study  

Microsoft Academic Search

:   The aim of the study was to analyse the 2-year follow-up of a series of patients with the diagnosis of undifferentiated spondyloarthropathy\\u000a (uSpA). A prospective study was carried out analysing 68 patients with symptomatic uSpA who fulfilled the European Spondylarthropathy\\u000a Study Group (ESSG) criteria for seronegative spondyloarthropathies (SpA) and were aged between 18 and 50 years. Inclusion\\u000a criteria included

P. D. Sampaio-Barros; M. B. Bertolo; M. H. S. Kraemer; J. F. Marques-Neto; A. M. Samara

2001-01-01

20

Ute Unit: Study Guide and Follow Up Activities.  

ERIC Educational Resources Information Center

The study guide and follow-up activities were designed primarily to give students a feeling of Ute life in the San Luis Valley in Colorado. The unit begins with six Southern Ute stories about the wolf and coyote, the race between the skunk and the coyote, the frog and the eagle, why the frog croaks, the bear (Que Ye Qat), and the two Indian…

North Conejos School District, Capulin, CO.

21

Education On Prehospital Pain Management: A Follow-Up Study  

PubMed Central

Introduction: The most common reason patients seek medical attention is pain. However, there may be significant delays in initiating prehospital pain therapy. In a 2001 quality improvement (QI) study, we demonstrated improvement in paramedic knowledge, perceptions, and management of pain. This follow-up study examines the impact of this QI program, repeated educational intervention (EI), and effectiveness of a new pain management standard operating procedure. Methods: 176 paramedics from 10 urban and suburban fire departments and two private ambulance services participated in a 3-hour EI. A survey was performed prior to the EI and repeated one month after the EI. We reviewed emergency medical services (EMS) runs with pain complaints prior to the EI and one month after the EI. Follow-up results were compared to our prior study. We performed data analysis using descriptive statistics and chi-square tests. Results: The authors reviewed 352 surveys and 438 EMS runs with pain complaints. Using the same survey questions, even before the EI, 2007 paramedics demonstrated significant improvement in the knowledge (18.2%; 95% CI 8.9%, 27.9%), perceptions (9.2%; 95% CI 6.5%, 11.9%), and management of pain (13.8%; 95% CI 11.3%, 16.2%) compared to 2001. Following EI in 2007, there were no significant improvements in the baseline knowledge (0%; 95% CI 5.3%, 5.3%) but significant improvements in the perceptions of pain principles (6.4%; 95% CI 3.9%, 9.0%) and the management of pain (14.7%; 95% CI 11.4%, 18.0%). Conclusion: In this follow up study, paramedics’ baseline knowledge, perceptions, and management of pain have all improved from 6 years ago. Following a repeat educational intervention, paramedics further improved their field management of pain suggesting paramedics will still benefit from both initial and also ongoing continuing education on the topic of pain management. PMID:23599840

French, Scott C.; Chan, Shu B.; Ramaker, Jill

2013-01-01

22

A follow-up study of former student health advocates.  

PubMed

Student health advocates (SHAs) are high school students who, under the supervision of the school nurse, provide health education and health promotion activities to other students via a peer education model. This 3-year follow-up study explored how the SHA experience influences career choice and attitudes of the participants. It also examined what motivates students to become SHAs, the benefits and drawbacks of SHA participation, how SHA involvement influenced career plans, and how SHAs perceive the role of the school nurse. Study results indicate that this innovative health education/promotion experience offered an opportunity for SHAs to express their interest in health and enhanced their sense of belonging, meaningful involvement, connection to learning, and caring relationships in the school setting. PMID:18052522

Streng, Nancy J

2007-12-01

23

Long-term Follow-up Study of Endovascularly Treated Intracranial Aneurysms  

PubMed Central

Summary Long-term follow-up studies after endovascular treatment for intracranial aneurysm are still rare and inconclusive. The aim of this study was to assess long-term clinical and angiographic outcome of patients with endovascularly treated aneurysms. The Clinical outcome of all 185 patients with endovascularly treated aneurysms were analyzed and 77 out of 122 surviving patients were examined with MRI and MRA nine to 16 years (mean 11 years) after the initial endovascular treatment. Sixty-three patients were deceased at the time of follow-up. The cause of death was aneurysm- related in 34 (54%) patients. The annual re- bleeding rate from the treated aneurysms was 1.3% in the ruptured group and 0.1% in the unruptured group. In long-term follow-up MRA 18 aneurysms (53%) were graded as complete, 11 aneurysms (32%) had neck remnants and five aneurysms (15%) were incompletely occluded in the ruptured group. Occlusion grade was lower in the unruptured group with 20 an- eurysms (41%) graded as complete, 11 (22%) had neck remnants and 18 (37%) were incomplete. However, only three aneurysms were unstable during the follow-up period and needed retreatment. Endovascular treatment of unruptured aneu- rysms showed incomplete angiographic outcome in 37% of cases. However, annual bleeding rate was as low as 0.1%. Endovascular treatment of ruptured aneurysms showed incomplete angiographic outcome in 15% of cases and the annual rebleeding rate was 1.3%. PMID:21162766

Pyysalo, L.M.; Keski-Nisula, L.H.; Niskakangas, T.T.; Kähärä, V.J.; Öhman, J.E.

2010-01-01

24

Antithymocyte globulin with or without cyclosporin A: 11-year follow-up of a randomized trial comparing treatments of aplastic anemia  

Microsoft Academic Search

Immunosuppression with antithymocyte globulin, (methyl)prednisolone, and cyclo- sporin A is considered the treatment of choice for the patient with aplastic ane- mia without a donor for standard-risk stem cell transplantation. This consen- sus is supported by the results of several series, including a randomized German trial. Here we report 11-year results of the latter trial. With stringent response crite- ria

Norbert Frickhofen; Hermann Heimpel; Joachim P. Kaltwasser; Hubert Schrezenmeier

25

Latex allergy: a follow up study of 1040 healthcare workers  

PubMed Central

Background Natural rubber latex allergy can cause skin and respiratory symptoms The aim of this study was to evaluate the prevalence and incidence of latex related symptoms and sensitisation among a large group of healthcare workers in Trieste hospitals, followed for three years before and after the introduction of powder?free gloves with low latex release. Methods In the years 1997–99 the authors evaluated 1040 healthcare workers exposed to latex allergen for latex related symptoms and sensitisation by means of a questionnaire, a medical examination, skin prick tests, and IgE specific antibody assay. The second evaluation was carried out in the years 2000–02, subsequent to the changeover to a powder?free environment. Results Glove related symptoms were seen in 21.8% of the nurses (227), mostly consisting of mild dermatitis: 38 (3.6%) complaining of contact urticaria and 24 (2.3%) of asthma and/or rhinitis. These symptoms were significantly related to skin prick tests positive to latex (OR?=?9.70; 95% CI 5.5 to 17) and to personal atopy (OR?=?2.29; 95% CI 1.6 to 3.2). Follow up was completed in 960 subjects (92.3%): 19 new subjects (2.4%) complained of itching erythema when using gloves, but none was prick positive to latex. Symptoms significantly improved and in most cases disappeared (p<0.0001). Conclusions Simple measures such as the avoidance of unnecessary glove use, the use of non?powdered latex gloves by all workers, and use of non?latex gloves by sensitised subjects can stop the progression of latex symptoms and can avoid new cases of sensitisation. PMID:16421390

Filon, F Larese; Radman, G

2006-01-01

26

Cannabis and schizophrenia: results of a follow-up study  

Microsoft Academic Search

A total of 39 schizophrenic patients with a history of current cannabis abuse at index admission was compared with a control\\u000a group of schizophrenics without substance abuse matched for age, gender, and year of admission. At follow-up after 68.7 ±\\u000a 28.3 months, 27\\/ 39 cases and 26\\/39 controls could be investigated. 8\\/27 cases (30%) had continued cannabis abuse, 6\\/27 (22%)

D. Caspari

1999-01-01

27

Callosal Tissue Loss in Multiple System Atrophy--A One-Year Follow-Up Study  

E-print Network

Callosal Tissue Loss in Multiple System Atrophy-- A One-Year Follow-Up Study Martina Minnerop, MD,1- sons of tissue-loss profiles (i.e., baseline versus follow-up) between patients and controls, revealed. Comparisons between baseline and follow-up, separately performed in patients and controls, revealed additional

Thompson, Paul

28

II. Methods and measures used for follow-up at 15 years of the English and Romanian Adoptee (ERA) study.  

PubMed

This chapter covers the methods and measures used in the ERA study, with a special focus on age 15 outcomes. First, we outline the sample participation rate for the 15-year follow-up-the percentages in all cases referring to the numbers at the time of initial sample contact. We then describe the measures used in this monograph, starting with those obtained at first contact with respect to functioning at the time of leaving institutional care. Because the group definitions relevant to the follow-up at age 15 are based on assessments at 6 and 11 years of age, we deal with the measures in those assessments first. At 11 years of age, we used a range of specific cognitive tests that might be of predictive value and those are detailed next. Then we discuss measures employed at the 15-year follow-up and those relevant to possible autism as used by Rutter in the separate assessment at 18-20 years. The monograph is structured around the possibility of deprivation-specific psychological patterns (DSPs), and hence on the strategies needed to test for them (see Rutter et al. in chapter I). Accordingly, the next section of this chapter deals with that strategy and details the measures taken to test the assumption's underlying the strategy. In our published papers concerning the 11-year follow-up, we tested whether outcomes were affected by the fact that some parents adopted mainly for altruistic reasons and others because of infertility-affected outcomes. Here we repeat this analysis in relation to DSPs. Similarly, we report findings on gender differences. The longitudinal study involved obtaining DNA for genotyping to examine the possibility that genetic features moderated the young people's response to institutional deprivation. Accordingly, in the next section of the chapter, we outline our genotyping approach. The final section of this chapter describes the statistical techniques we employed in our analyses. PMID:20500632

2010-04-01

29

A Follow-Up Study in Vocational Rehabilitation.  

ERIC Educational Resources Information Center

A study investigated consumer satisfaction and employment status for successfully rehabilitated vocational rehabilitation (VR) clients from a central Kansas general caseload and identified clients in need of further services. Four independent variables were studied: severity of disability, disability groups, time elapsed since closure, and work…

Main, Douglas M.

30

Adolescents and death on television: A follow-up study  

Microsoft Academic Search

The television viewing habits and perceptions of television violence and death of 712 academically heterogeneous students, grades 6 through 12, from three urban and three rural schools in north Florida were surveyed using a TV questionnaire revised from a prior study. The survey indicated that adolescents enjoy watching violent TV programs but are ambivalent about allowing younger children to watch

Hannelore Wass; Jana L. Raup; Harry H. Sisler

1989-01-01

31

FINAL REPORT: NATIONAL CHILDREN'S STUDY FOCUS GROUPS - FOLLOW-UP  

EPA Science Inventory

The purpose of this work assignment was to add to our knowledge of the issues that will affect recruitment and retention of pregnant women into the National Children's Study by conducting 14 focus groups comprised of pregnant women, couples, and parents of young chi...

32

Ancillary Findings of a Follow-Up Study.  

ERIC Educational Resources Information Center

A followup study of recent graduates from the undergraduate teacher education program at Bowling Green State University (Ohio) resulted in findings on their perceived needs, proficiencies, and what produced the indicated proficiencies. The subjects also evaluated their present attitudes toward teaching. In addition, the principal or department…

Pigge, Fred L.

33

Assessment reactivity to follow-up in a study of women's treatment for alcohol dependence.  

PubMed

Little research has been conducted on symptom reductions in response to assessments in clinical trials, despite the impact such reactivity may have on interpretation of outcomes. Reactivity to data collection procedures during post-treatment follow-up may obscure treatment effects. The current study examined whether female participants (n=102) in a trial of cognitive-behavioral treatment for alcohol dependence had lower drinking quantity and frequency immediately after participating in follow-up assessments. Repeated measures ANOVAs were used to compare each participant's drinking among two-week time periods immediately before the follow-up, directly after the follow-up, and between follow-ups. No assessment reactivity was found for 9 or 15 month follow-up interviews, but was suggested at a 12 month in-person interview. PMID:18261860

Worden, Blaise L; McCrady, Barbara S; Epstein, Elizabeth E

2008-06-01

34

"A Research Oriented Elementary Education Student Teaching Program": A Follow-Up Study.  

ERIC Educational Resources Information Center

This is a report of a follow-up study of an elementary education student teaching program carried out in 1961-64. The intent of the program was to foster more experimental and analytic attitudes toward teaching rather than postponing a concern for research until graduate study. The follow-up study was an attempt to ascertain to what extent three…

Callaway, Rolland; Baruch, Steven

35

Study Protocol, Sample Characteristics, and Loss to Follow-Up: The OPPERA Prospective Cohort Study  

PubMed Central

When studying incidence of pain conditions such as temporomandibular disorders (TMDs), repeated monitoring is needed in prospective cohort studies. However, monitoring methods usually have limitations and, over a period of years, some loss to follow-up is inevitable. The OPPERA prospective cohort study of first-onset TMD screened for symptoms using quarterly questionnaires and examined symptomatic participants to definitively ascertain TMD incidence. During the median 2.8-year observation period, 16% of the 3,263 enrollees completed no follow-up questionnaires, others provided incomplete follow-up, and examinations were not conducted for one third of symptomatic episodes. Although screening methods and examinations were found to have excellent reliability and validity, they were not perfect. Loss to follow-up varied according to some putative TMD risk factors, although multiple imputation to correct the problem suggested that bias was minimal. A second method of multiple imputation that evaluated bias associated with omitted and dubious examinations revealed a slight underestimate of incidence and some small biases in hazard ratios used to quantify effects of risk factors. Although “bottom line” statistical conclusions were not affected, multiply-imputed estimates should be considered when evaluating the large number of risk factors under investigation in the OPPERA study. Perspective These findings support the validity of the OPPERA prospective cohort study for the purpose of investigating the etiology of first-onset TMD, providing the foundation for other papers investigating risk factors hypothesized in the OPPERA project. PMID:24275220

Bair, Eric; Brownstein, Naomi C.; Ohrbach, Richard; Greenspan, Joel D.; Dubner, Ron; Fillingim, Roger B.; Maixner, William; Smith, Shad; Diatchenko, Luda; Gonzalez, Yoly; Gordon, Sharon; Lim, Pei-Feng; Ribeiro-Dasilva, Margarete; Dampier, Dawn; Knott, Charles; Slade, Gary D.

2013-01-01

36

Automated Telecommunication to Obtain Longitudinal Follow-up in a Multicenter Cross-sectional COPD Study  

PubMed Central

Background It can be challenging to maintain longitudinal follow-up of subjects in clinical studies. COPDGene is a multicenter, observational study designed to identify genetic factors associated with COPD and to characterize COPD-related phenotypes. To obtain follow-up data on patient's vital status and outcomes, the COPDGene Longitudinal Follow-up (LFU) Program was developed to supplement its parent study. Methods/Results We used a telecommunication system that employed automated telephone contact or web-based questions to obtain longitudinal follow-up data in our subjects. A branching questionnaire asked about exacerbations, new therapies, smoking status, development of co-morbid conditions, and general health status. Study coordinators contacted subjects who did not respond to one of the automated methods. We enrolled 10,383 subjects in the COPDGene study. As of August 29, 2011, 7,959 subjects completed 19,955 surveys. On the first survey, 68.8% of subjects who completed their survey did so by electronic means, while 31.3% required coordinator phone follow-up. On each subsequent survey the number of subjects who completed their survey by electronic means increased, while the number of subjects who required coordinator follow-up decreased. Despite many of the patients in the cohort being chronically ill and elderly, there was broad acceptance of the system with over half the cohort using electronic response methods. Conclusions The COPDGene LFU Study demonstrated that telecommunications was an effective way to obtain longitudinal follow-up of subjects in a large multicenter study. Web-based and automated phone contacts are accepted by research subjects and could serve as a model for LFU in future studies. PMID:22676387

Stewart, Jeffrey I.; Moyle, Sarah; Criner, Gerard J.; Wilson, Carla; Tanner, Ron; Bowler, Russell P.; Crapo, James D.; Zeldin, Robert K.; Make, Barry J.; Regan, Elizabeth A.

2013-01-01

37

Respiratory response to tobacco dust exposure among biddi binders: A follow up and bronchodilator study  

PubMed Central

Intorduction: The tobacco dusts get air borne during biddi making and it is inhaled by the biddi binders, which affects their health. Results: In a follow-up study, 86 biddi binders (male, 41; female, 45) were studied at a gap of 2 years. A high respiratory morbidity was observed among males than females both in the initial and follow-up study. The main complaints such as cough, sputum, and breathlessness showed high prevalence rates in the follow-up study. The high prevalence rates of weakness, giddiness, chronic diarrhea, and dyspepsia were noted in most of the cases the above complaints showed higher rates in the follow-up study. Pulmonary function test (PFT) values in the follow-up study of male and female biddi binders showed lowered compared with the initial study of same gender. In male and female biddi binders, the lung volumes SVC, FVC, FEV1, and the flow rates FEF0.2-1.2 l, FEF25%-75%, FEF75%-85% were significantly lowered in the follow-up study compared with the initial study. Age-related decrement in PFT was observed in both the studies. In nonsmokers, smokers, and ex-smokers, the PFT values are lowered. The current smokers have the lowest values in both the studies. With the administration of the bronchodilator aerosol (salbutamol) in 63 biddi binders (male, 27; female, 36), the effect of bronchodilator aerosol on the PFT parameters showed significant changes as all PFT parameters showed positive bronchodilatation. Conclusion: The pattern of bronchodilator response on PFT values of the biddi binders suggests that the obstructions in the airways are reversible in nature.

Chattopadhyay, B. P.; Gangopadhyay, P. K.; Das, Anirban; Alam, Sk. Jane; Hossain, Mubarak; Chowdhury, Anirban; Kundu, Amar

2014-01-01

38

A follow-up study of Non-teacher certified Agricultural Education Department graduates  

E-print Network

A FOLLOW-UP STUDY OF NON-TEACHER CERTIFIED AGRICULTURAL EDUCATION DEPARTMENT GRADUATES A Thesis by AMBER LYNN DAILEY Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for thc degree... of MASTER OF SCIENCE August 1999 Maj or Subj ect: Agricultural Education A FOLLOW-UP STUDY OF NON-TEACHER CERTIFIED AGRICULTURAL EDUCATION DEPARTMENT GRADUATES A Thesis by AMBER LYNN DAILEY Submitted to Texas A&M University in partial fulfillment...

Dailey, Amber Lynn

1999-01-01

39

Nursing Education Follow-Up Study--1982 R.N.'s.  

ERIC Educational Resources Information Center

In 1982, a follow-up study of nursing graduates of the Bakersfield College Registered Nursing (RN) program was conducted to obtain information that would lead to improvement in program quality and to a better match between supply and demand in the local nursing labor market. In addition, the study compared results with similar studies conducted…

Scott, David C.

40

Timing of Discharge Follow-up for Acute Pulmonary Embolism: Retrospective Cohort Study  

PubMed Central

Introduction Historically, emergency department (ED) patients with pulmonary embolism (PE) have been admitted for several days of inpatient care. Growing evidence suggests that selected ED patients with PE can be safely discharged home after a short length of stay. However, the optimal timing of follow up is unknown. We hypothesized that higher-risk patients with short length of stay (<24 hours from ED registration) would more commonly receive expedited follow up (?3 days). Methods This retrospective cohort study included adults treated for acute PE in six community EDs. We ascertained the PE Severity Index risk class (for 30-day mortality), facility length of stay, the first follow-up clinician encounter, unscheduled return ED visits ?3 days, 5-day PE-related readmissions, and 30-day all-cause mortality. Stratifying by risk class, we used multivariable analysis to examine age- and sex-adjusted associations between length of stay and expedited follow up. Results The mean age of our 175 patients was 63.2 (±16.8) years. Overall, 93.1% (n=163) of our cohort received follow up within one week of discharge. Fifty-six patients (32.0%) were sent home within 24 hours and 100 (57.1%) received expedited follow up, often by telephone (67/100). The short and longer length-of-stay groups were comparable in age and sex, but differed in rates of low-risk status (63% vs 37%; p<0.01) and expedited follow up (70% vs 51%; p=0.03). After adjustment, we found that short length of stay was independently associated with expedited follow up in higher-risk patients (adjusted odds ratio [aOR] 3.5; 95% CI [1.0–11.8]; p=0.04), but not in low-risk patients (aOR 2.2; 95% CI [0.8–5.7]; p=0.11). Adverse outcomes were uncommon (<2%) and were not significantly different between the two length-of-stay groups. Conclusion Higher-risk patients with acute PE and short length of stay more commonly received expedited follow up in our community setting than other groups of patients. These practice patterns are associated with low rates of 30-day adverse events.

Vinson, David R.; Ballard, Dustin W.; Huang, Jie; Rauchwerger, Adina S.; Reed, Mary E.; Mark, Dustin G.

2015-01-01

41

Sources of Validity Evidence for Educational and Psychological Tests: A Follow-Up Study  

ERIC Educational Resources Information Center

This study followed up on previous work that examined the incidence of reporting evidence based on test consequences in "Mental Measurements Yearbook". In the present study, additional possible outlets for what has been called "consequential validity" evidence were investigated, including all articles published in the past 10 years in several…

Cizek, Gregory J.; Bowen, Daniel; Church, Keri

2010-01-01

42

Personnel Needs in School Psychology: A 10-Year Follow-Up Study on Predicted Personnel Shortages  

ERIC Educational Resources Information Center

Concerns regarding whether a sufficient supply of school psychologists exists have been evident for decades. Studies have predicted that school psychology would face a critical personnel shortage that would peak in 2010, but continue into the foreseeable future. The current study is a 10-year follow-up investigation based on previously published…

Castillo, Jose M.; Curtis, Michael J.; Tan, Sim Yin

2014-01-01

43

Extending a Community of Care beyond the Ninth Grade: A Follow-Up Study  

ERIC Educational Resources Information Center

This qualitative within-site case study ("N" = 10) is a follow-up study to a 2006-2007 investigation that analyzed how 1 high school created a community of care for its ninth-grade students through the implementation of a ninth-grade transition program--Freshman Focus. All participants were interviewed again 3 years later during…

Ellerbrock, Cheryl R.; Kiefer, Sarah M.

2013-01-01

44

Ten Years Later: A Follow-Up Study of Professors Still Working after Age 70  

ERIC Educational Resources Information Center

Little is known about the impact of the end of mandatory retirement on professors over the long term. This follow-up study investigated the ten-year experience of professors who chose not to retire from a major research university after the elimination of the age 70 mandatory retirement in 1994. The initial interview study was conducted in 1998…

Dorfman, Lorraine T.

2009-01-01

45

Follow-Up Study of 1986 Harper Career Alumni. Volume XVI, No. 9.  

ERIC Educational Resources Information Center

As part of an ongoing evaluation of the career programs at Illinois' William Rainey Harper College (WRHC), a follow-up study of 1986 program graduates was conducted and results were compared with previous years. Questionnaires were sent to 491 students who earned 48 or more hours during the 1985-86 academic year at WRHC. Study findings, based on a…

Lucas, John A.

46

A Follow-Up Study on Word and Non-Word Reading Skills in Down Syndrome  

ERIC Educational Resources Information Center

The current study was designed to trace changes in the relationship between non-word reading and irregular word reading on the one hand, and between phonological awareness and non-word reading on the other, through a follow-up study of a group of individuals with Down syndrome. Twelve individuals with Down syndrome, whose data were originally…

Roch, Maja; Jarrold, Christopher

2012-01-01

47

Sierra Leone's Former Child Soldiers: A Follow-Up Study of Psychosocial Adjustment and Community Reintegration  

ERIC Educational Resources Information Center

This is the first prospective study to investigate psychosocial adjustment in male and female former child soldiers (ages 10-18; n = 156, 12% female). The study began in Sierra Leone in 2002 and was designed to examine both risk and protective factors in psychosocial adjustment. Over the 2-year period of follow-up, youth who had wounded or killed…

Betancourt, Theresa Stichick; Borisova, Ivelina Ivanova; Williams, Timothy Philip; Brennan, Robert T.; Whitfield, Theodore H.; de la Soudiere, Marie; Williamson, John; Gilman, Stephen E.

2010-01-01

48

Perceived Levels of Cultural Competence for School Social Workers: A Follow-up Study  

ERIC Educational Resources Information Center

The purpose of this article is to report on findings from a follow-up study that examined the relationship among social work education programs, postgraduate professional development, and school social workers' perceived levels of cultural competence in practice with urban minority youth. The initial study demonstrated that African Americans…

Teasley, Martell L.; Archuleta, Adrian; Miller, Christina

2014-01-01

49

Er:YAG laser ablation: 5-11 years prospective study  

NASA Astrophysics Data System (ADS)

The Er:YAG laser at 2940 nm has been proposed for use in dental cavity preparation and removal of carious enamel and dentin. The purpose of the present study was to determine the effect of the Er:YAG laser ablation in treating dental caries after a period from 5 to 11 years. For this study, 133 cavities were chosen, and for their reparation of it the three restorative materials were used. Baseline examination was made in the following intervals: one week, 1 year, and from 5 to 11 years after cavity preparation and placement of filling material. Clinical assessments were carried out in accordance with the US Public Health Service System. The follow-up included: the marginal ridge, marginal adaptation, anatomic form, caries, color match, cavo surface margin discoloration, surface smoothness, and postoperative sensitivity. Er:YAG laser ablation is an excellent method for treating frontal teeth, i.e., incisors, canines, premolars, and initial occlusal caries of molars. However, visual control of non-contact therapy is necessary. Er:YAG laser ablation is safe, and it strongly reduces pain. The laser treatment markedly decreases the unpleasant sound and vibration.

Dostalova, Tatjana; Jelinkova, Helena; Nemec, Michal; Sulc, Jan; Miyagi, Mitsunobu

2005-03-01

50

Major adverse cardiovascular events in adult congenital heart disease: a population-based follow-up study from Taiwan  

PubMed Central

Background The aim of the present study was to identify the long-term major adverse cardiovascular events (MACE) in adult congenital heart disease (ConHD) patients in Taiwan. Methods From the National Health Insurance Research Database (1997-2010), adult patients (?18 years) with ConHD were identified and compared to non-ConHD control patients. The primary end point was the incidence of MACE. Cox proportional hazards models were used to compute hazard ratios as estimates for multivariate adjusted relative risks with or without adjusting for age and sex. Results A total of 3,267 adult patients with ConHD were identified between 2000 and 2003 with a median follow-up of 11 years till December 31, 2010. The five most common types of ConHD were atrial septal defects, ventricular septal defects, patent ductus arteriosus, tetralogy of Fallot, and pulmonary stenosis. Overall, the incidence of MACE was 4.0-fold higher in the ConHD group compared with the controls. After adjustment for age and gender, the patients with ConHD had an increased risk of heart failure, malignant dysrhythmia, acute coronary syndrome, and stroke. The adult ConHD patients had a decreased life-long risk of MACE if they received surgical correction, especially in the patients with atrial septal defects. Conclusions After a median of 11 years of follow-up, the Taiwanese patients with ConHD were at an increased risk of life-long cardiovascular MACE, including heart failure, stroke, acute coronary syndrome, and malignant dysrhythmia. Surgical correction may help to decrease long-term MACE in ConHD patients, especially those with ASD. PMID:24655794

2014-01-01

51

Scorpio single radius total knee arthroplasty. A minimal five-year follow-up multicentric study  

Microsoft Academic Search

Purpose  Our goal was to evaluate the five-year follow-up results of the Scorpio single radius total knee arthroplasty.\\u000a \\u000a \\u000a \\u000a Method  We performed a retrospective study based upon a multicentre database to evaluate the minimum five-year follow-up clinical\\u000a and radiological results of 747 patients (831 knees) who underwent primary Scorpio single radius total knee arthroplasty.\\u000a \\u000a \\u000a \\u000a \\u000a Results  The mean age of the patients was 71.9 years. At

Frédéric Borrione; Paul Bonnevialle; Christian Mabit; Olivier Guingand; Denis Bertin; François Bonnomet; Christophe Denis; Gilles Gagna

52

Proportional hazards regression in epidemiologic follow-up studies: an intuitive consideration of primary time scale.  

PubMed

In epidemiologic cohort studies of chronic diseases, such as heart disease or cancer, confounding by age can bias the estimated effects of risk factors under study. With Cox proportional-hazards regression modeling in such studies, it would generally be recommended that chronological age be handled nonparametrically as the primary time scale. However, studies involving baseline measurements of biomarkers or other factors frequently use follow-up time since measurement as the primary time scale, with no explicit justification. The effects of age are adjusted for by modeling age at entry as a parametric covariate. Parametric adjustment raises the question of model adequacy, in that it assumes a known functional relationship between age and disease, whereas using age as the primary time scale does not. We illustrate this graphically and show intuitively why the parametric approach to age adjustment using follow-up time as the primary time scale provides a poor approximation to age-specific incidence. Adequate parametric adjustment for age could require extensive modeling, which is wasteful, given the simplicity of using age as the primary time scale. Furthermore, the underlying hazard with follow-up time based on arbitrary timing of study initiation may have no inherent meaning in terms of risk. Given the potential for biased risk estimates, age should be considered as the preferred time scale for proportional-hazards regression with epidemiologic follow-up data when confounding by age is a concern. PMID:22517300

Cologne, John; Hsu, Wan-Ling; Abbott, Robert D; Ohishi, Waka; Grant, Eric J; Fujiwara, Saeko; Cullings, Harry M

2012-07-01

53

The Center for the Arts and Sciences Follow-Up Study of 1991 Graduates. Evaluation Report.  

ERIC Educational Resources Information Center

Findings of a follow-up study that examined the experiences of 1991 high school graduates of the Center for the Arts and Sciences (CAS) program in Saginaw, Michigan, are presented in this paper. A survey mailed to 33 graduates received 16 responses. Findings indicate that all respondents were enrolled in a school, college, or training program. The…

Saginaw Public Schools, MI. Dept. of Evaluation Services.

54

Colorado Even Start Follow-Up Study: Trinidad State Junior College.  

ERIC Educational Resources Information Center

Even Start family literacy programs are integrated adult education, early childhood education, and parent support components intended to break the intergenerational cycle of poverty and low literacy. In Spring of 2002, a follow-up study of one Even Start project was conducted to assess the long-term effects of Even Start programming for families.…

Anderson, Beckie

55

A Follow-Up Study of the ABRACADABRA Web-Based Literacy Intervention in Grade 1  

ERIC Educational Resources Information Center

This paper reports the follow-up of a randomised control trial study of the ABRACADABRA web-based literacy intervention that contrasted synthetic versus analytic phonics (Comaskey, Savage & Abrami, 2009) in kindergarten children from urban low-SES backgrounds. Participants who received a "synthetic" phonics+phoneme awareness training (n = 26) or…

Di Stasio, Maria Rosaria; Savage, Robert; Abrami, Philip C.

2012-01-01

56

A multicentre follow-up study of 1152 patients with myasthenia gravis in Italy  

Microsoft Academic Search

A multicentre retrospective study was carried out on the characteristics and course of myasthenia gravis (MG) in Italy. Data from 1152 patients, fairly representative of the myasthenic population seeking medical advice, were analysed for diagnostic criteria, clinical aspects and therapeutic approaches. Mean follow-up was 4.9 years. The disease was correctly diagnosed within 2 years of the onset in 80% of

R. Mantegazza; E. Beghi; D. Pareyson; C. Antozzi; D. Peluchetti; A. Sghirlanzoni; V. Cosi; M. Lombardi; G. Piccolo; P. Tonali; A. Evoli; E. Ricci; A. P. Batocchi; C. Angelini; G. F. MicaglioS; G. Marconi; R. Taiuti; L. Bergamini; L. Durelli; F. Cornelio

1990-01-01

57

The natural course of myasthenia gravis: a long term follow up study  

Microsoft Academic Search

A long term follow up study is presented of 73 patients with myasthenia gravis, living in Amsterdam between 1926 and 1965. In the period 1961-65 the annual incidence was 3.1, the prevalence 53 per million. Maximum severity of the disease occurred during the first seven years after onset in 87%. Eighteen (29%) patients died, of whom eight had a thymoma

H J Oosterhuis

1989-01-01

58

Workloads, Achievement and Stress: Two Follow-Up Studies of Teacher Time in Key Stage 1.  

ERIC Educational Resources Information Center

The first of two follow-up studies, involving 53 infant teachers in England and Wales, was conducted to monitor changes in the workloads of teachers as the national curriculum and assessment were brought in following ministerial promises to reduce the burdens imposed on teachers by the implementation of the national curriculum. Data were collected…

Campbell, R. J.; And Others

59

Maryland Community Colleges Student Follow-up Study: First-time Students, Fall 1972.  

ERIC Educational Resources Information Center

This document reports the methodology and results of the third annual statewide student follow-up study of the Maryland community colleges. Questionnaires were sent to 19,634 persons who were first-time students in a Maryland community college in fall, 1972. Response rate was 48%. A sequential sampling procedure was used to test for nonrespondent…

Tschechtelin, James D.; And Others

60

Follow-Up Study of 1993 Dental Hygiene Graduates. Volume XXII, Number 17, June 1994.  

ERIC Educational Resources Information Center

In an effort to evaluate the effectiveness of its dental hygiene program, William Rainey Harper College (WRHC), in Palatine, Illinois, conducted a follow-up study of its dental hygiene students. The survey instrument was mailed to all 31 1993 dental hygiene associate degree graduates, and a response rate of 97% (n=30) was attained. Results of the…

Holt, Marianne; Lucas, John A.

61

Follow-Up Study of 1984 Harper Career Alumni. Research Report Series Volume XV, No. 7.  

ERIC Educational Resources Information Center

As part of an ongoing evaluation of the career programs at William Rainey Harper College (WRHC), a follow-up study was conducted of 1984 program graduates, and results were compared with those from earlier surveys. Questionnaires were sent to 763 students who graduated from career programs in 1983-84, requesting demographic information, current…

Lucas, John A.

62

Follow-Up Study of 1981 Harper Transfer Alumni. Volume XII, No. 13.  

ERIC Educational Resources Information Center

In January 1982, a study was conducted at William Rainey Harper College (WRHC) to gather follow-up data on transfer-oriented students 1 year after they had accumulated at least 48 semester hours of credit. All 820 alumni meeting these criteria were mailed a survey form asking about their current status, evaluation of WRHC, and activity patterns…

Lucas, John A.

63

Follow-Up Study of 1990 Dental Hygiene Graduates. Volume XX, No. 1.  

ERIC Educational Resources Information Center

In a continuing effort to measure the quality of their Dental Hygiene program, explore the need for changes, and substantiate the program's goals for accreditation standards, a follow-up study was conducted of the 1990 Dental Hygiene program graduates from William Rainey Harper (WRHC) College in Palatine, Illinois. A survey was mailed to all 30…

Holt, Marianne; Lucas, John A.

64

Eight-Year Follow-Up Study of Black Hawk College's Non-Traditional Degree Graduates.  

ERIC Educational Resources Information Center

During 1980, Black Hawk Community College conducted a follow-up study of the 92 students who had graduated with an Associate in Liberal Arts (ALS) degree since 1973. The degree differs from the college's more traditional degrees in emphasizing less restrictive residency requirements, opportunities to develop a personalized course of instruction,…

Stevens, Mary A.

65

WHI and WHIMS follow-up and human studies of soy isoflavones  

Microsoft Academic Search

Recent follow-up analyses of the previous findings from the Women's Health Initiative and the Women's Health Initiative Memory Study confirmed some health benefits of estrogen- containing hormone therapy (HT) in women within 10 years from the onset of menopause. However, the potential risks associated with long-term administration of HT, such as breast cancer and stroke, remain a concern for therapy

Liqin Zhao; Roberta Diaz Brinton

66

Follow-Up Study of 1988 Dental Hygiene Graduates. Volume XVII, No. 7.  

ERIC Educational Resources Information Center

In 1989, a follow-up study was conducted of the 1988 graduates of William Rainey Harper College's (WRHC's) Dental Hygiene program in order to measure the quality of the program, explore the need for changes, and substantiate the program's goals for accreditation standards. A survey was mailed to all 27 associate degree graduates, requesting…

Holt, Marianne; Flaherty, Toni

67

Follow-Up Study of 1988 Nursing Graduates. Volume XVIII, No. 8.  

ERIC Educational Resources Information Center

In 1989, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. Questionnaires were mailed to 105 nursing students who graduated in 1988. Results were compared with previous surveys…

Dincher, J.; Meltesen, Cal

68

Follow-Up Study of 1990 Nursing Graduates. Volume XX, No. 10.  

ERIC Educational Resources Information Center

In 1990, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) in Palatine, Illinois, to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. All 98 nursing students who earned 48 credit hours in 1990 were mailed questionnaires 1 year…

Lucas, J.; Meltesen, C.

69

Follow-Up Study of 1992 Nursing Graduates. Volume XXII, Number 15, March 1994.  

ERIC Educational Resources Information Center

In an attempt to evaluate the effectiveness of its nursing program, William Rainey Harper College (WRHC) (Illinois) conducted a follow-up study of 1992 nursing graduates or alumni. In spring 1993, a survey instrument, inquiring about employment status, future educational plans, and evaluation of their experience at WRHC, was mailed to all 142 WRHC…

Lucas, John A.; Meltesen, Cal

70

Follow-Up Study of 1986 Nursing Graduates. Volume XVI, No. 12.  

ERIC Educational Resources Information Center

In spring 1987, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) to examine employment patterns, further education plans, and graduates' evaluation of particular aspects of their WRHC experience. Questionnaires were mailed to 112 nursing students who graduated with an associate degree in 1986.…

Dincher, J.; Flaherty, A.

71

Nursing Education Follow-Up Study--1974 R.Ns. a Year After Graduation.  

ERIC Educational Resources Information Center

A group of 41 registered nursing graduates of the 1974 class at Bakersfield College was surveyed in the summer of 1974 as part of a nursing education follow-up study. In the summer of 1975, the same group was surveyed again in order to compare the perceptions and aspirations reported by the graduates one year after graduation with those reported…

Scott, David C.

72

Follow-Up Study of Children Referred to Developmental Evaluation Services for Children (DESC).  

ERIC Educational Resources Information Center

Developmental Evaluation Services for Children (DESC) provides in-depth medical and educational diagnostic services for children in Montgomery County, Maryland, who are under 6 years of age and who are suspected of having handicapping conditions in two or more areas of development. This follow-up study was designed to determine the progress of…

Cooper, Judith A.; Hebbeler, Kathleen M.

73

Clinically diagnosed childhood asthma and follow-up of symptoms in a Swedish case control study  

Microsoft Academic Search

BACKGROUND: Childhood asthma has risen dramatically not only in the western societies and now forms a major and still increasing public health problem. The aims of this study were to follow up at the age of ten the patterns of asthma symptoms and associations among children with a clinically diagnosed asthma in a sizeable urban-rural community and to in compare

Eduardo Roel; Åshild Faresjö; Olle Zetterström; Erik Trell; Tomas Faresjö

2005-01-01

74

The Treatment of Parasomnias with Hypnosis: a 5-Year Follow-Up Study  

PubMed Central

Study Objectives: This study involves a replication and extension of a previous one reported by Hurwitz et al (1991) on the treatment of certain parasomnias with hypnosis. Methods: Thirty-six patients (17 females), mean age 32.7 years (range 6–71). Four were children aged 6 to 16. All had chronic, “functionally autonomous” (self-sustaining) parasomnias. All underwent 1 or 2 hypnotherapy sessions and were then followed by questionnaire for 5 years. Results: Of the 36 patients, 45.4% were symptom-free or at least much improved at the 1-month follow-up, 42.2% at the 18-month follow-up, and 40.5% at the 5-year follow-up. Conclusions: One or 2 sessions of hypnotherapy might be an efficient first-line therapy for patients with certain types of parasomnias. Citation: Hauri PJ; Silber MH; Boeve BF. The treatment of parasomnias with hypnosis: a 5-year follow-up study. J Clin Sleep Med 2007;3(4):369-373. PMID:17694725

Hauri, Peter J.; Silber, Michael H.; Boeve, Bradley F.

2007-01-01

75

Using Home Spirometry for Follow up of Lung Transplant Recipients: “A Pilot Study  

PubMed Central

Background Lung transplantation is considered the ultimate treatment for some patients, but due to the specific condition of patients undergoing it, follow up is a major concern. The aim of this study was to evaluate the role of home spirometry in follow up of lung transplant recipients and early detection of complications in these patients. Materials and Methods A PC-based portable spirometry set was used to evaluate the well being of two lung transplant recipients on a regular daily basis for a 6-month period. Patient satisfaction and compliance, and device sensitivity in detecting complications were evaluated. Results of follow up were compared with 2 matched control patients. Results Patient adherence to home spirometry was 80% in one and 61% in the other patient and both patients were satisfied with the method, although this satisfaction declined towards the end of the study period. The main reason for low adherence was insufficient internet access. This method succeeded in early detection of infectious complications. Conclusion Home spirometry seems to be a reliable method for follow up of lung transplant recipients, but further studies in a larger group of patients is recommended. PMID:25191451

Fadaizadeh, Lida; Shafaghi, Shadi; Hosseini, Mahsa Sadat; Ghoroghi, Azadeh

2013-01-01

76

Observational study on Takotsubo-like cardiomyopathy: clinical features, diagnosis, prognosis and follow-up  

PubMed Central

Objectives The present study attempts to identify appropriate elements that may contribute to clarify the broad clinical features (diagnosis, care, complication and prognosis) of Takotsubo-like cardiomyopathy for improving its management. Design study Observational study. Setting Primary level of care referred to the emergency department of Vannini Hospital, Rome, Italy. Participants The study population consisted of 75 patients, 72 of the them were women and 3 were men with a mean age of 71.9±9.6?years. Methods From February 2004 to November 2010, prospectively included 84 consecutive patients diagnosed for suspected Takotsubo-like cardiomyopathy. To be eligible, patients had to meet all the Mayo clinic criteria in the absence of neurological trauma or intracranial haemorrhage. Moreover, those patients that at follow-up still presented alteration of acute phase at ECG and echocardiogram were excluded. Thus, 75 patients comprised the study population. To follow-up 19 patients were lost. Results None of 75 patients died in acute phase. All patients were promptly discharged (8.4±4.4?days), since they recovered their normal functional status without symptoms. Follow-up information was available for 56 patients. At a mean follow-up time of 2.2±2?years (range, 0.1–6.8?years) two octogenarian patients (2.6%) died because of sudden cardiac death and pulmonary embolism, respectively. The Takotsubo-like cardiomyopathy recurred in one patient. Conclusions The results of this study support the previous reports about the good prognosis, also in critically ill patients, of Takotsubo-like cardiomyopathy. Further assessment will be needed to determine a careful and sustained follow-up for choosing the best care and foreseeing the recurrences of this emerging condition. PMID:23065445

Cacciotti, Luca; Passaseo, Ilaria; Marazzi, Giuseppe; Camastra, Giovanni; Campolongo, Giuseppe; Beni, Sergio; Lupparelli, Fabrizio; Ansalone, Gerardo

2012-01-01

77

Sudomotor dysfunction in autoimmune autonomic ganglionopathy: a follow-up study  

PubMed Central

Objective We have previously shown that sudomotor dysfunction in autoimmune autonomic ganglionopathy is severe, widespread, and predominantly post-ganglionic. However, the long-term changes in sudomotor function have not been studied in detail. Our objective was to characterize the long-term changes in sudomotor dysfunction in patients with autoimmune autonomic ganglionopathy. Methods Changes in sudomotor function were compared in a cohort of nine ?3 nAChR antibody positive autoimmune autonomic ganglionopathy patients over an approximate 5-year period. Standard measurements of sudomotor function were used including the thermoregulatory sweat test and quantitative sudomotor axon reflex test. Results Total body anhidrosis on thermoregulatory sweat testing showed improvement in four of nine patients. Quantitative sudomotor axon reflex testing for both forearm and foot sites was variable with four of nine patients showing improvement in total sweat output. Distribution of sudomotor dysfunction at follow-up was post-ganglionic in seven of nine patients at the foot site and three of nine patients at the forearm site. Overall, sudomotor dysfunction was post-ganglionic in seven of nine patients throughout the follow-up period (62.4 ± 19.4 months). Interpretation Sudomotor dysfunction in autoimmune autonomic ganglionopathy was severe and widespread throughout the follow-up period for the majority of patients studied. Sudomotor dysfunction was predominantly post-ganglionic throughout the follow-up period. PMID:22127477

Kimpinski, Kurt; Iodice, Valeria; Sandroni, Paola; Fealey, Robert D.; Vernino, Steven

2012-01-01

78

75 FR 54965 - Proposed Information Collection (Follow-Up Study of a National Cohort of Gulf War and Gulf Era...  

Federal Register 2010, 2011, 2012, 2013, 2014

...AFFAIRS [OMB Control No. 2900-New...Collection (Follow-Up Study of...Management System (FDMS...Titles: Follow-Up Study of...10-0488a. OMB Control Number: OMB Control No. 2900-New...unexplained multi-system illnesses...Burden a. Follow-Up Study...

2010-09-09

79

75 FR 54445 - Proposed Information Collection (Follow-Up Study of a National Cohort of Gulf War and Gulf Era...  

Federal Register 2010, 2011, 2012, 2013, 2014

...AFFAIRS [OMB Control No. 2900-New...Collection (Follow-Up Study of...Management System (FDMS...Titles: Follow-Up Study of...10-0488a. OMB Control Number: OMB Control No. 2900-New...unexplained multi-system illnesses...Burden: a. Follow-Up Study...

2010-09-07

80

Impact of diabetes mellitus on pneumonia mortality in a senior population: results from the NHANES III follow-up study  

PubMed Central

Objective To examine whether diabetes mellitus increases the risk of pneumonia mortality among seniors in the U.S. general population. Methods & Results The NHANES III follow-up study data were used. After excluding individuals from other minorities, being hospitalized with pneumonia in the previous year at baseline, or death of pneumonia during the first year of follow-up, a total of 3,707 subjects aged 65 years or older (1,794 men and 1,913 women) who had no missing information on variables for the analysis were included. Approximately 16% of seniors at baseline were diabetics, which was defined as either having been diagnosed by a physician, currently taking pills/insulin lowering blood glucose, or HbA1c higher than 6.4%. During an average 11 years of follow-up, a total of 98 deaths due to pneumonia were recorded (ICD-10: J12–J18). Cox-regression models were used to estimate the risk association between pneumonia mortality and diabetes mellitus. After adjustment for the covariates at baseline, the hazard ratios of pneumonia death were 1.30 (95% CI: 0.64–2.70) for pre-diabetics and 2.28 (95% CI: 1.18–4.39) for diabetics, respectively. Among those covariates, only age (HR (95% CI); 1.16 (1.13–1.20)), gender as female (0.35 (0.22–0.61)) and physical fitness measured as having no problem walking 1+ mile during the previous month (0.38 (0.20–0.67)) reached statistical significance. Conclusions The results suggest that diabetes mellitus is a strong risk predictor of pneumonia mortality and the evaluation of physical fitness may also be useful in the risk prediction of pneumonia mortality for seniors. PMID:24133515

Liu, Jian

2013-01-01

81

Long-term Ultrasonographic Follow-up Study of Gastric Motility in Patients with Functional Dyspepsia  

PubMed Central

Although patients with functional dyspepsia complain of epigastric symptoms, the relation between these symptoms and gastric motility remains controversial. There are few reports on the clinical course of functional dyspepsia, including changes in gastric motility, observed over a considerably long period. We conducted a study to examine association between changes in symptoms and changes in ultrasonographically evaluated gastric motility over a long-term follow-up period in patients with functional dyspepsia. Forty patients (18 men, 22 women; mean age, 53.7 years) with functional dyspepsia were followed up by medical interview, physical examination, endoscopy, and ultrasonography for gastric motility. Follow-up ranged from 1.0 to 7.8 years (mean, 3.0 years). Ultrasonographic evaluation of gastric motility included gastric emptying rate and antral contractions. During the follow-up period, patients were treated with proton pump inhibitors, H2-blockers, or prokinetics. Symptoms improved in 21 patients (group A), but symptoms persisted or worsened in 19 patients (group B). There were no significant differences in clinical characteristics between the two groups. Gastric motility improved in group A but not in group B. In conclusion, improved gastric motility appears to correspond to and may explain improved symptoms in some patients with functional dyspepsia. PMID:18385832

Kamino, Daisuke; Manabe, Noriaki; Hata, Jiro; Haruma, Ken; Tanaka, Shinji; Chayama, Kazuaki

2008-01-01

82

Axonal damage accumulates in the progressive phase of multiple sclerosis: three year follow up study  

PubMed Central

Background: Neurofilament phosphoforms (Nf) are principal components of the axoskeleton released during axonal injury. Cerebrospinal fluid (CSF) levels of Nf phosphoforms might be useful surrogate markers for disability in multiple sclerosis (MS), aid in distinguishing clinical subtypes, and provide valuable prognostic information. Method: Thirty four patients with MS were included in a three year follow up study along with 318 controls with other non-inflammatory neurological diseases. CSF levels of two Nf heavy chain (NfH) phosphoforms (NfHSMI35, NfHSMI34) were quantified at baseline and three year follow up using new ELISA techniques. Levels of NfH phosphoforms, the degree of phosphorylation (NfHSMI34:NfHSMI35 ratio), and changes in NfH levels between baseline and follow up (?NfH) were related to the clinical phenotype (RR or SP/PP), to three clinical scales (Kurtzke's EDSS, ambulation index (AI), and nine hole peg test (9HPT)), and to progression of disability. Results: A significantly higher proportion (59%) of patients with SP/PPMS experienced an increase in NfHSMI35 levels between baseline and follow up compared with those with RRMS (14%, p<0.05). CSF NfHSMI34 levels at baseline were higher in patients with SP/PP (11 pg/ml) compared with RR (7 pg/ml, p<0.05) and NfHSMI35 levels were higher at follow up in SP/PP (129 pg/ml) compared with levels below assay sensitivity in RR (p<0.05). NfHSMI35 correlated with the EDSS (rs = 0.54, p<0.01), the AI (rs = 0.42, p<0.05), and the 9HPT (rs = 0.59, p<0.01) at follow up. Conclusion: The increase in NfH during the progressive phase of the disease together with the correlation of NfHSMI35 with all clinical scales at follow up suggests that cumulative axonal loss is responsible for sustained disability and that high NfHSMI35 levels are a poor prognostic sign. PMID:15654034

Petzold, A; Eikelenboom, M; Keir, G; Grant, D; Lazeron, R; Polman, C; Uitdehaag, B; Thompson, E; Giovannoni, G

2005-01-01

83

Femoral Neck Fractures in Children: A Follow-Up Study of 19 Cases  

Microsoft Academic Search

\\u000a Abstract\\u000a   We studied 20 fractures of the neck of femur in 19 patients under the age of 16 years that were treated in the period from\\u000a 1998 to 2004. There were nine boys and ten girls with an average age of 11 years. There was one case of Delbet type I (transepiphyseal\\u000a separation). Thirteen cases were of Delbet type II

Masoud Norouzi; Mohamad N. Naderi

2009-01-01

84

Replication of genetic linkage by follow-up of previously studied pedigrees  

SciTech Connect

Independent replication of linkage in previously studied pedigrees is desirable when genetic heterogeneity is suspected or when the illness is very rare. When the likelihood of the new data in this type of replication study is computed as conditional on the previously reported linkage results, it can be considered independent. The authors describe a simulation method using the SLINK program in which the initial data are fixed and newly genotyped individuals are simulated under [theta] = .01 and [theta] = .50. These give appropriate lod score criteria for rejection and acceptance of linkage in the follow-up study, which take into account the original marker genotypes in the data. An estimate of the power to detect linkage in the follow-up data is also generated. 13 refs., 1 fig., 1 tab.

Gershon, E.S.; Goldin, L.R. (National Institute of Mental Health, Bethesda, MD (United States))

1994-04-01

85

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CODING: FOLLOW UP QUESTIONNAIRE (UA-D-11.0)  

EPA Science Inventory

The purpose of this SOP is to define the coding strategy for the Follow Up Questionnaire. This questionnaire was developed for use in the Arizona NHEXAS project and the "Border" study. Household and individual follow-up data were combined in a single Follow-up Questionnaire data...

86

Psychiatric disorders in children in long-term residential care: a follow-up study.  

PubMed

Ninety-two children who had been examined in a psychiatric study of five to twelve year-olds in long-term residential care were followed up four years later. Three-quarters were still in children's homes, but over half had been moved to different establishments. At both the original study and follow-up, the majority showed evidence of psychiatric disorder. Considerable continuity of behavioural pattern was found, particularly amongst those who originally had antisocial disorders, who were also most likely to have had changes of care-taker during the four years. It is suggested that the persistence of their disorder may be due to a vicious circle of unacceptable behaviour and adult rejection. PMID:497616

Wolkind, S; Renton, G

1979-08-01

87

Slater revisited: 6 year follow up study of patients with medically unexplained motor symptoms  

PubMed Central

Objective: To investigate psychiatric and neurological morbidity, diagnostic stability, and indicators of prognosis in patients previously identified as having medically unexplained motor symptoms. Design: Follow up study. Setting: National Hospital for Neurology and Neurosurgery, London—a secondary and tertiary referral hospital for neurological disorders. Subjects: 73 patients with medically unexplained motor symptoms admitted consecutively in 1989-91. 35 (48%) patients had absence of motor function (for example, hemiplegia) and 38 (52%) had abnormal motor activity (for example, tremor, dystonia, or ataxia). Main outcome measures: Neurological clinical diagnosis at face to face reassessment by a neurologist and a psychiatric diagnosis after a standardised assessment interview—the schedule for affective disorders and schizophrenia—conducted by a psychiatrist. Results: Good follow up data were available for 64 subjects (88%). Only three subjects had new organic neurological disorders at follow up that fully or partly explained their previous symptoms. 44/59 (75%) subjects had had psychiatric disorders; in 33 (75%) patients, the psychiatric diagnosis coincided with their unexplained motor symptoms. 31/59 (45%) patients had a personality disorder. Three subjects had developed new psychiatric illnesses at follow up, but in only one did the diagnosis account for the previous motor symptoms. Resolution of physical symptoms was associated with short length of symptoms, comorbid psychiatric disorder, and a change in marital status during follow up. Conclusions: Unlike Slater’s study of 1965, a low incidence of physical or psychiatric diagnoses which explained these patients’ symptoms or disability was found. However, a high level of psychiatric comorbidity existed. Key messages Motor symptoms that remain unexplained medically despite thorough investigation are a common clinical problem, but the emergence of a subsequent organic explanation for these symptoms is rare The prevalence of coexistent affective and anxiety disorders is high and many patients also have a personality disorder Patients with a shorter duration of symptoms and coexistent anxiety or depression are likely to do better at follow up Reinvestigation of these patients is both expensive and potentially dangerous and should be avoided where no clear clinical indication exists PMID:9518908

Crimlisk, Helen L; Bhatia, Kailash; Cope, Helen; David, Anthony; Marsden, C David; Ron, Maria A

1998-01-01

88

Polycystic ovarian morphology and bulimia nervosa: a 9-year follow-up study  

Microsoft Academic Search

Objective: To examine long-term changes in polycystic ovarian morphology in women with polycystic ovaries and bulimia nervosa after treatment of the latter condition.Design: Longitudinal follow-up study.Setting: Eating disorder unit of a university hospital.Patient(s): Eight women originally treated for bulimia nervosa (T0) who underwent ultrasonography up to 2 years after treatment (T1) and had a second ultrasonographic scan 9 years later

John F Morgan; Sara E McCluskey; Joan N Brunton; J Hubert Lacey

2002-01-01

89

Shaken baby syndrome in Switzerland: results of a prospective follow-up study, 2002–2007  

Microsoft Academic Search

Since the incidence of shaken baby syndrome in Switzerland was not known, we conducted a nationwide prospective follow-up\\u000a study for a 5-year period (from 2002 to 2007). The data were collected through the Swiss Pediatric Surveillance Unit. Inclusion\\u000a criteria were the presence, in a child ?6 years of age, of 1) more than or equal to two clinical symptoms (altered consciousness,

Manuela Fanconi; Ulrich Lips

2010-01-01

90

Predicting various fragility fractures in women by forearm bone densitometry: A follow-up study  

Microsoft Academic Search

This is a follow-up of a previous study on the predictive power of bone mineral measurements; two more observation years have been added. A group of women (n=1076) had their forearm bone mineral content (BMC) measured from 1970–1976. All fractures that occurred in 1975–1987 (13 years) were recorded. Four hundred sixty-nine fragility fractures occurred during the collection period. Again, it

Per Gärdsell; Olof Johnell; Bo E. Nilsson; Bo Gullberg

1993-01-01

91

Relapse After Methylprednisolone Oral Minipulse Therapy in Childhood Vitiligo: A 12-Month Follow-Up Study  

PubMed Central

Background: Oral minipulse (OMP) therapy with methylprednisolone is presently one of the most common oral treatments used for progressive vitiligo in children. The treatment is usually given for a period of 6 months during which majority of patients are reported to go into remission. However, there are no follow-up studies to comment upon what happens to the disease after OMP therapy is withdrawn. Aim of the study: To document the incidence of relapse over a period of 1 year after OMP therapy is stopped in children with vitiligo. Materials and Methods: The study was conducted in 180 patients of childhood vitiligo (<15 years of age) who had been on OMP therapy with oral methylprednisolone for at least 6 months and who had achieved a complete remission of their disease during the treatment period. The enrolled patients were followed up for a period of 1 year and examined clinically for any sign of reactivation of their disease over either the old lesions or at any new area of the body. Results: Forty-two patients were lost and could not complete the follow-up period of 1 year. Out of the 138 patients available at the end of 1 year, relapse was observed in 48 patients (34.8%). Rest of 90 patients remained in remission over the follow-up period of 1 year. Relapse was more common in patients below 10 years of age (47.4%) as compared with older children (25.9%). Conclusion: Relapse after using methylprednisolone OMP therapy in children with vitiligo is quite common especially in younger age groups. Studies are needed to see whether these relapses could be avoided by giving the treatment for a period longer than 6 months. PMID:23716799

Majid, Imran; Imran, Saher

2013-01-01

92

Selective mutism: follow-up study 1 year after end of treatment.  

PubMed

Cognitive behavioral therapy (CBT) is generally considered the recommended approach for selective mutism (SM). Prospective follow-up studies of treated SM and predictors of outcome are scarce. We have developed a CBT home and school-based intervention for children with SM previously found to increase speech in a pilot efficacy study and in a randomized controlled treatment study. In the present report we provide outcome data 1 year after having completed the 6-month course of CBT for 24 children with SM, aged 3-9 years (mean age 6.5 years, 16 girls). Primary outcome measures were the teacher rated School Speech Questionnaire (SSQ) and diagnostic status. At follow-up, no significant decline was found on the SSQ scores. Age and severity of SM had a significant effect upon outcome, as measured by the SSQ. Eight children still fulfilled diagnostic criteria for SM, four were in remission, and 12 children were without diagnosis. Younger children improved more, as 78 % of the children aged 3-5 years did not have SM, compared with 33 % of children aged 6-9 years. Treatment gain was upheld at follow-up. Greater improvement in the younger children highlights the importance of an early intervention. PMID:25267381

Oerbeck, Beate; Stein, Murray B; Pripp, Are H; Kristensen, Hanne

2014-09-30

93

Motility Disturbances in the Tube Versus Trabeculectomy Study During the First Year of Follow-up  

PubMed Central

PURPOSE To describe the preoperative and postoperative motility disturbances encountered in the Tube Versus Trabeculectomy (TVT) Study during the first year of follow-up. DESIGN Multicenter randomized clinical trial. METHODS SETTINGS: Seventeen clinical centers. POPULATION: Patients 18 to 85 years old who had previous trabeculectomy and/or cataract surgery and uncontrolled glaucoma with intraocular pressure ?18 mm Hg and ?40 mm Hg on maximum tolerated medical therapy. INTERVENTIONS: 350-mm2 Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC). MAIN OUTCOME MEASURES: Preoperative and postoperative evaluation of ocular motility and diplopia. RESULTS Motility disturbances were detected in 55 patients (28%) at baseline. New-onset persistent diplopia was reported in 5 patients (5%) in the tube group and no patients in the trabeculectomy group at 1 year (P = .06). A new postoperative motility disturbance developed or worsened in 7 patients (9.9%) in the tube group and no patients in the trabeculectomy group during the first year of follow-up (P = .005). Postoperative motility disturbances were also associated with increasing age (P < .001) and right eye surgery (P = .044). CONCLUSIONS Preoperative motility disturbances were common among patients in the TVT Study. New postoperative motility disturbances were more frequent following tube shunt surgery than trabeculectomy with MMC after 1 year of follow-up. PMID:19038375

Rauscher, Frederick M.; Gedde, Steven J.; Schiffman, Joyce C.; Feuer, William J.; Barton, Keith; Lee, Richard K.

2014-01-01

94

Cardiac assessment of veteran endurance athletes: a 12 year follow up study  

PubMed Central

OBJECTIVES: Sustained aerobic dynamic exercise is beneficial in preventing cardiovascular disease. The effect of lifelong endurance exercise on cardiac structure and function is less well documented, however. A 12 year follow up of 20 veteran athletes was performed, as longitudinal studies in such cohorts are rare. METHODS: Routine echocardiography was repeated as was resting, exercise, and 24 hour electrocardiography. RESULTS: Nineteen returned for screening. Mean (SD) age was 67 (6.2) years (range 56-83). Two individuals had had permanent pacemakers implanted (one for symptomatic atrial fibrillation with complete heart block, the other for asystole lasting up to 15 seconds). Only two athletes had asystolic pauses in excess of two seconds compared with seven athletes in 1985. Of these seven, five had no asystole on follow up. Two of these five had reduced their average running distance by about 15-20 miles a week. One athlete sustained an acute myocardial infarction during a competitive race in 1988. Three athletes had undergone coronary arteriography during the 12 years of follow up but none had obstructive coronary artery disease. Ten of 19 (53%) had echo evidence of left ventricular hypertrophy in 1997 but only two (11%) had left ventricular dilatation. Ten athletes had ventricular couplets on follow up compared with only two in 1985. CONCLUSIONS: Although the benefits of moderate regular exercise are undisputed, high intensity lifelong endurance exercise may be associated with altered cardiac structure and function. These adaptations to more extreme forms of exercise merit caution in the interpretation of standard cardiac investigations in the older athletic population. On rare occasions, these changes may be deleterious. ??? PMID:10450477

Hood, S.; Northcote, R. J.

1999-01-01

95

Prospective Image Registration for Automated Scan Prescription of Follow-up Knee Images in Quantitative Studies  

PubMed Central

Consistent scan prescription for MRI of the knee is very important for accurate comparison of images in a longitudinal study. However, consistent scan region selection is difficult due the complexity of the knee joint. We propose a novel method for registering knee images using a mutual information registration algorithm to align images in a baseline and follow-up exam. The output of the registration algorithm, three translations and three Euler angles, is then used to redefine the region to be imaged and acquire an identical oblique imaging volume in the follow-up exam as in the baseline. This algorithm is robust to articulation of the knee and anatomical abnormalities due to disease (e.g. osteophytes). The registration method is performed only on the distal femur and is not affected by the proximal tibia or soft tissues. We have incorporated this approach in a clinical MR system and have demonstrated its utility in automatically obtaining consistent scan regions between baseline and follow-up examinations, thus improving the precision of quantitative evaluation of cartilage. Results show an improvement with prospective registration in the coefficient of variation for cartilage thickness, cartilage volume, and T2 relaxation measurements. PMID:21546186

Goldenstein, Janet; Schooler, Joseph; Crane, Jason C.; Ozhinsky, Eugene; Pialat, Jean-Baptiste; Carballido-Gamio, Julio; Majumdar, Sharmila

2011-01-01

96

Stability of alexithymia in late adolescence: results of a 4-year follow-up study.  

PubMed

The aim of the present study was to assess the stability of alexithymia in adolescents and the effects of parental factors and social support thereon. The sample comprised 315 late adolescents, of whom 259 were female and 56 male. At baseline, the mean age of the subjects was 19 years (range 17-21 years). The follow-up period was 4 years (2008-2012). The 20-item Toronto Alexithymia Scale (TAS-20) was used for the assessment of alexithymia both at baseline and follow-up. The Multidimensional Scale of Perceived Social Support (MSPSS) and the Parental Bonding Instrument (PBI) were used as measures at baseline. Regarding absolute stability, the changes in the TAS-20 total scores and two subscales (DIF and EOT) were statistically significant but the effect sizes for the changes were small (Cohen?s d 0.21-0.24). The test-retest correlations for the TAS-20 total and subscale scores were high (?=0.50-0.64, P<0.001), indicating relative stability. While several parental and social support variables were associated with alexithymia at baseline, low social support from friends was the only to predict higher alexithymia at follow-up. Alexithymia is a stable personality trait also in late adolescence. Low social support from friends is related to alexithymia in young adulthood. PMID:24953425

Karukivi, Max; Pölönen, Tuukka; Vahlberg, Tero; Saikkonen, Suvi; Saarijärvi, Simo

2014-10-30

97

Patient relationship management: an overview and study of a follow-up system.  

PubMed

Customer relationship management research is utilized to explain the need for a more patient-oriented support in patient care. This article presents a European study on how various hospital units of a single healthcare organization have utilized a patient relationship management system--in particular a patient treatment follow-up system--and how it affects patient care and the knowledge work performed by the medical staff. Eight physicians were interviewed at a university hospital on whether patient treatment was improved through a follow-up system that had been in use in the case organization for three years. The interviewees represented various hospital units, and all of them had used the system at their own unit. The results indicate that it is possible to improve patient care through more personalized treatment. The follow-up treatment system seems to be a tool to create and maintain better communication with the patients rather than just a technological solution. It may help better understand and analyze both individual patients and patient groups. For individual physicians it provides a way to reflect professional skills. The system was lacking in its support for one-to-one communication with patients. Nevertheless, the system is an example of patient relationship management which may help healthcare units to move towards a more patient-oriented care. PMID:19267028

Oinas-Kukkonen, Harri; Räisänen, Teppo; Hummastenniemi, Niko

2008-01-01

98

Breast Cancer and the Environment on Long Island Follow-up Study  

Cancer.gov

Dr. Marilie Gammon, of the University of North Carolina at Chapel Hill, and collaborating scientists in New York City, conducted a follow-up study on 1,098 women with breast cancer who participated in the parent population-based case-control study of Long Island women. The primary aims of the study were to determine whether environmental and other lifestyle factors influence breast cancer survival and overall survival among a population-based sample of Long Island women diagnosed with the disease.

99

U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--FOLLOW-UP QUESTIONNAIRE DATA  

EPA Science Inventory

The Follow-up Questionnaire data set provides information concerning the activities within the household during the sampling week. The information is from 201 Follow-up Questionnaires for 91 households. Medication and supplemental dietary information is provided. The Follow-up...

100

Australian Aboriginal Birth Cohort study: follow-up processes at 20 years  

PubMed Central

Background In 1987, a prospective study of an Australian Aboriginal Birth Cohort was established focusing on the relationships of fetal and childhood growth with the risk of chronic adult disease. However as the study is being conducted in a highly marginalized population it is also an important resource for cross-sectional descriptive and analytical studies. The aim of this paper is to describe the processes of the third follow up which was conducted 20 years after recruitment at birth. Methods Progressive steps in a multiphase protocol were used for tracing, with modifications for the expected rural or urban location of the participants. Results Of the original 686 cohort participants recruited 68 were untraced and 27 were known to have died. Of the 591 available for examination 122 were not examined; 11 of these were refusals and the remainder were not seen for logistical reasons relating to inclement weather, mobility of participants and single participants living in very remote locations. Conclusion The high retention rate of this follow-up 20 years after birth recruitment is a testament to the development of successful multiphase protocols aimed at overcoming the challenges of tracing a cohort over a widespread remote area and also to the perseverance of the study personnel. We also interpret the high retention rate as a reflection of the good will of the wider Aboriginal community towards this study and that researchers interactions with the community were positive. The continued follow-up of this life course study now seems feasible and there are plans to trace and reexamine the cohort at age 25 years. PMID:19775475

2009-01-01

101

CORONIS - International study of caesarean section surgical techniques: the follow-up study  

PubMed Central

Background The CORONIS Trial was a 2×2×2×2×2 non-regular, fractional, factorial trial of five pairs of alternative caesarean section surgical techniques on a range of short-term outcomes, the primary outcome being a composite of maternal death or infectious morbidity. The consequences of different surgical techniques on longer term outcomes have not been well assessed in previous studies. Such outcomes include those related to subsequent pregnancy: mode of delivery; abnormal placentation (e.g. accreta); postpartum hysterectomy, as well as longer term pelvic problems: pain, urinary problems, infertility. The Coronis Follow-up Study aims to measure and compare the incidence of these outcomes between the randomised groups at around three years after women participated in the CORONIS Trial. Methods/Design This study will assess the following null hypotheses: In women who underwent delivery by caesarean section, no differences will be detected with respect to a range of long-term outcomes when comparing the following five pairs of alternative surgical techniques evaluated in the CORONIS Trial: 1. Blunt versus sharp abdominal entry 2. Exteriorisation of the uterus for repair versus intra-abdominal repair 3. Single versus double layer closure of the uterus 4. Closure versus non-closure of the peritoneum (pelvic and parietal) 5. Chromic catgut versus Polyglactin-910 for uterine repair The outcomes will include (1) women’s health: pelvic pain; dysmenorrhoea; deep dyspareunia; urinary symptoms; laparoscopy; hysterectomy; tubal/ovarian surgery; abdominal hernias; bowel obstruction; infertility; death. (2) Outcomes of subsequent pregnancies: inter-pregnancy interval; pregnancy outcome; gestation at delivery; mode of delivery; pregnancy complications; surgery during or following delivery. Discussion The results of this follow-up study will have importance for all pregnant women and for health professionals who provide care for pregnant women. Although the results will have been collected in seven countries with limited health care resources (Argentina, Chile, Ghana, India, Kenya, Pakistan, Sudan) any differences in outcomes associated with different surgical techniques are likely to be generalisable throughout the world. Trial registration ISRCTN31089967 PMID:24261693

2013-01-01

102

Diffusion-weighted magnetic resonance imaging in Marchiafava-Bignami disease: follow-up studies.  

PubMed

Marchiafava-Bignami disease (MBD), an acute toxic demyelination of the corpus callosum in alcoholics, is associated with poor evolution in the majority of patients. We report here the early and late diffusion magnetic resonance imaging (MRI) and apparent diffusion coefficient (ADC) studies of two patients suffering from MBD with favourable outcome. Diffusion and anatomical MRI changes were parallel to the clinical evolution, suggesting that MRI studies can be helpful for diagnosis and follow-up. Unlike in stroke, restricted diffusion on ADC maps does not seem to be a sign of irreversibility. PMID:15918025

Hlaihel, C; Gonnaud, P-M; Champin, S; Rousset, H; Tran-Minh, V-A; Cotton, F

2005-07-01

103

Undifferentiated spondyloarthritis in a heterogeneous Brazilian population: an eight-year follow-up study.  

PubMed

The aim of the present study was to describe the outcomes of Brazilian patients with undifferentiated spondyloarthritis during an eight-year follow-up period. Patients fulfilling the European Spondyloarthritis (SpA) Study Group Classification Criteria were enrolled. Forty patients were seen at baseline, and 36 participated in the follow-up study. Twenty-three (58%) were female, and there were 24 (60%) African Brazilians enrolled. HLA-B27 was positive in 18 (45%) patients. At disease onset, the first presenting symptoms were pure peripheral manifestations in 26 (72.2%) patients. After the study period, mixed disease (axial + peripheral) predominated occurring in 25 (69.4%) patients. The Assessment of SpA International society (ASAS) classification criteria for axial SpA were fulfilled by 77% of patients, and the ASAS criteria for peripheral SpA were fulfilled by 59% of patients. After 2.5 years, 6 (16.7%) of the 36 patients fulfilled the modified New York Criteria for ankylosing spondylitis and 1 (2.7%) progressed to psoriatic arthritis. A total of 10 (27.8%) patients progressed to definite SpA during the eight-year study period. Buttock pain (p = 0.006, OR 10.55; 95% CI 2.00-65.90) and low-grade radiographic sacroiliitis (p = 0.025, OR = 11.50; 95% CI 1.33-83.39) at baseline were associated with definite SpA. Thus, in this Brazilian cohort, which had a predominance of female African-Brazilian patients, prevalent peripheral onset symptoms were followed by a high frequency of axial manifestations during the follow-up period. Evidence of clinical or radiological sacroiliitis was associated with progression to definite SpA. PMID:23765202

da Cruz Lage, Ricardo; de Souza Bomtempo, Carlos Alexandre; Kakehasi, Adriana Maria; de Carvalho, Marco Antônio Parreiras

2014-07-01

104

Zolpidem Use and the Risk of Injury: A Population-Based Follow-Up Study  

PubMed Central

Background While an association between zolpidem use and fracture and road accident was previously proposed, this study aimed to further explore the frequency and risk of a wide spectrum of injuries in subjects prescribed with zolpidem in Taiwan. Methods We identified 77,036 subjects who received Zolpidem treatment between 2005 and 2007. We randomly selected 77,036 comparison subjects who were frequency-matched based-on their demographic profiles. We individually tracked each subject for a 90-day period to identify those who subsequently suffered an injury. Cox proportional hazards regressions were performed to calculate the hazard ratio of injury between the two groups. Results The incidence rate of injury during the 90-day follow-up period for the total subjects was 18.11 (95% CI?=?17.69–18.54) per 100 person-years; this was 24.35 (95% CI?=?23.66–25.05) and 11.86 (95% CI?=?11.39–12.36) for the study and comparison cohort, respectively. After adjusting for demographic variables, the hazard ratio (HR) of injury during the 90-day follow-up period for study subjects was 1.83 (95% CI?=?1.73–1.94) that of comparison subjects. Additionally, compared to comparison subjects, the adjusted HR of injury during the 90-day follow-up period for study subjects who were prescribed Zolpidem for >30 days was as high as 2.17 (95% CI?=?2.05–2.32). The adjusted HR of injury to blood vessels for study subjects was particularly high when compared to comparison subjects (HR?=?6.34; 95% CI?=?1.37–29.38). Conclusions We found that patients prescribed with Zolpidem were at a higher risk for a wide range of injuries. PMID:23826304

Lin, Ching-Chun; Wang, Li-Hsuan; Kang, Jiunn-Horng

2013-01-01

105

Postoperative Complications in the Tube Versus Trabeculectomy (TVT) Study During Five Years of Follow-up  

PubMed Central

Purpose To describe postoperative complications encountered in the Tube Versus Trabeculectomy (TVT) Study during 5 years of follow-up. Design Multicenter randomized clinical trial. Methods Settings Seventeen clinical centers. Study Population Patients 18 to 85 years of age who had previous trabeculectomy and/or cataract extraction with intraocular lens implantation and uncontrolled glaucoma with intraocular pressure (IOP) ?18 mm Hg and ?40 mm Hg on maximum tolerated medical therapy. Interventions Tube shunt (350-mm2 Baerveldt glaucoma implant) or trabeculectomy with mitomycin C (MMC 0.4 mg/mL for 4 minutes). Main Outcome Measures Surgical complications, reoperations for complications, visual acuity, and cataract progression. Results Early postoperative complications occurred in 22 patients (21%) in the tube group and 39 patients (37%) in the trabeculectomy group (P = .012). Late postoperative complications developed in 36 patients (34%) in the tube group and 38 patients (36%) in the trabeculectomy group during 5 years of follow-up (P = .81). The rate of reoperation for complications was 22% in the tube group and 18% in the trabeculectomy group (P = .29). Cataract extraction was performed in 13 phakic eyes (54%) in the tube group and 9 phakic eyes (43%) in the trabeculectomy group (P = .43). Conclusions A large number of surgical complications were observed in the TVT Study, but most were transient and self-limited. The incidence of early postoperative complications was higher following trabeculectomy with MMC than tube shunt surgery. The rates of late postoperative complications, reoperation for complications, and cataract extraction were similar with both surgical procedures after 5 years of follow-up. PMID:22244522

Gedde, Steven J.; Herndon, Leon W.; Brandt, James D.; Budenz, Donald L.; Feuer, William J.; Schiffman, Joyce C.

2013-01-01

106

Changes in leisure-time physical activity after transition to retirement: a follow-up study  

Microsoft Academic Search

Background  Retirement is a major life change that is likely to affect lifestyles. The aim of this study was to examine changes in leisure-time\\u000a physical activity of moderate and vigorous intensity among ageing employees facing transition to retirement over a follow-up\\u000a of 5-7 years.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  The baseline data were collected by questionnaire surveys in 2000-2002 among 40-60-year-old employees of the City of

Jouni Lahti; Mikko Laaksonen; Eero Lahelma; Ossi Rahkonen

2011-01-01

107

Optical Studies of Space Debris at GEO: Survey and Follow-up with Two Telescopes  

NASA Technical Reports Server (NTRS)

For 14 nights in March 2007, we used two telescopes at the Cerro Tololo Inter-American Observatory (CTIO) in Chile to study the nature of space debris at Geosynchronous Earth Orbit (GEO). In this project one telescope was dedicated to survey operations, while a second telescope was used for follow-up observations for orbits and colors. The goal was to obtain orbital and photometric information on every faint object found with the survey telescope. Thus we concentrate on objects fainter than R = 15th magnitude.

Seitzer, P.; Abercomby, K. J.; Rodriquez, H. M.; Barker, E. S.

2007-01-01

108

Ultrasonographically detected gallbladder polyps: A reason for concern? A seven-year follow-up study  

PubMed Central

Background The management of coincidental detected gallbladder polyps (GP) is still nebulous. There are few published data regarding their long-term growth. Objective of the present study was to investigate the prevalence and growth of gallbladder polyps in a survey of unselected subjects from the general population of a complete rural community. Methods A total of 2,415 subjects (1,261 women; 1,154 men) underwent ultrasound examination of the gallbladder, in November 1996 as part of a prospective study. Subjects in whom GP were detected at the initial survey underwent follow-up ultrasound examinations after 30 and 84 months. Results At the initial survey gallbladder polyps were detected in 34 subjects (1.4%; females: 1.1%, range 14 to 74 years; males: 1.7%, range 19 to 63 years). Median diameter was 5 ± 2.1 mm (range 2 to10 mm) at the initial survey, 5 mm ± 2.8 mm (range 2 to 12 mm) at 30 months and 4 ± 2.3 mm (range 2 to 9 mm) at 84 months. At the time of first follow-up no change in diameter was found in 81.0% (n = 17), reduction in diameter in 4.8% (n = 1) and increase in diameter in 14.3% (n = 3). At the time of second follow-up no increase in polyp diameter was found in 76.9% (n = 10) and reduction in diameter in 7.7% (n = 1). No evidence of malignant disease of the gallbladder was found. Conclusion Over a period of seven years little change was measured in the diameter of gallbladder polyps. There was no evidence of malignant disease of the gallbladder in any subject. PMID:18793401

Kratzer, Wolfgang; Haenle, Mark M; Voegtle, Andrea; Mason, Richard A; Akinli, Atilla S; Hirschbuehl, Klaus; Schuler, Andreas; Kaechele, Volker

2008-01-01

109

Health Professionals Follow-up Study (HPFS): Prospective Studies of Diet and Cancer in Men and Women  

Cancer.gov

The grant provides for continued follow-up for and research on the Health Professionals Follow-up Study (HPFS) of 51,529 men who completed an extensive dietary questionnaire first in 1986 and again in 1990, 1994,1998, 2002, 2006, and 2010. The program project grant also supports the food composition database and nutrient analysis system used by the Nurses' Health Study, Nurses' Health Study II, and many other studies.

110

Factors associated with remission of eczema in children: a population-based follow-up study.  

PubMed

The aim of this study was to analyse factors associated with remission of atopic dermatitis (AD) in childhood. A population-based AD cohort of 894 children aged 1-3 years from a cross-sectional baseline study in 2000 was followed up in 2005. The association between remission, background, health, lifestyle, and environmental variables was estimated with crude and multivariable logistic regression. At follow-up, 52% of the children had remission. Independent factors at baseline predicting remission were: milder eczema (adjusted odds ratio (aOR), 1.43; 95% confidence interval (95% CI) 1.16-1.77); later onset of eczema (aOR 1.40; 95% CI 1.08-1.80); non-flexural eczema (aOR 2.57; 95% CI 1.62-4.09); no food allergy (aOR 1.51; 95% CI 1.11-2.04), and rural living (aOR 1.48; 95% CI 1.07-2.05). Certain aspects of AD and rural living were important for remission, but despite the initial hypotheses to the contrary, the environmental factors examined in this paper were not substantial predictors of remission. PMID:24037118

von Kobyletzki, Laura B; Bornehag, Carl-Gustaf; Breeze, Elizabeth; Larsson, Malin; Lindström, Cecilia Boman; Svensson, Åke

2014-03-01

111

A follow up study on the efficacy of metadoxine in the treatment of alcohol dependence  

PubMed Central

Background We carried out a three months follow-up study on the efficacy of metadoxine in a cohort of alcoholics admitted to the Alcohol misuse Long-term Treatment (ALT) Unit – University of Pisa (Italy). We analyzed the clinical data, psychometric tests and blood tests of 160 alcoholics on admission and after 3 months of treatment. We compared 58 pts treated with metadoxine (MET) with 102 pts who did not receive (NULL) any drug as an adjunct to the psycho-educational interventions provided by the ALT Unit. Results At follow-up, the patients in treatment with metadoxine showed a significant improvement in the rate of complete abstinence (44.8% vs. 21.6%; chi square: 8.45, df = 1, p < 0.0037). Furthermore, the number of drop-outs at three months of treatment was also significantly lower in the MET than in the NULL group (17% vs. 57%; chi square of 23.22, df = 1, p < 0.001). Conclusion Our findings support the use of metadoxine in the management of alcohol dependence. However, randomized clinical trials are necessary to confirm and replicate them. This study raises the importance of identifying new pharmacological compounds effective on the outcome of alcoholism in order to help patients to best adhere to treatment programs and to prevent the development of mental and physical complications due to chronic and heavy use of alcohol. PMID:17176456

Guerrini, Irene; Gentili, Claudio; Nelli, Gloria; Guazzelli, Mario

2006-01-01

112

Characteristics and prognosis of lone atrial fibrillation. 30-year follow-up in the Framingham Study.  

PubMed

In 30 years of follow-up of 5,209 participants in the Framingham Study, 193 men and 183 women developed atrial fibrillation (AF). Among this group, "lone" AF occurred in 32 men and 11 women free of coronary heart disease, congestive heart failure, rheumatic heart disease, and hypertensive cardiovascular disease. To determine the characteristics and prognosis of lone AF, each case was matched to controls in the remaining Framingham sample. Comparisons indicated that levels of several risk factors associated with coronary heart disease were similar between the two groups. Atrial fibrillation cases, however, had significantly higher rates of preexisting nonspecific T- or ST-wave abnormalities and intraventricular block as determined by electrocardiograms. Follow-up for new cardiovascular events indicated similar rates of coronary heart disease and congestive heart failure, but the rate of strokes was significantly greater in the lone AF group. Findings suggest that subjects with lone AF, despite similar cardiovascular risk profiles to normal controls, have a distinct preponderance of preexisting electrocardiographic abnormalities. Furthermore, contrary to general belief, lone AF is not a benign condition; it has a serious prognosis, indicating a greater need for detection and treatment. PMID:4068186

Brand, F N; Abbott, R D; Kannel, W B; Wolf, P A

1985-12-27

113

Memory self-efficacy predicts memory performance: results from a 6-year follow-up study.  

PubMed

The purpose of this study was to examine the relationship between memory self-efficacy (MSE) and a 6-year follow-up assessment of memory functioning in a sample of Dutch older adults. MSE was assessed by a Dutch abridged version of the Metamemory in Adulthood questionnaire (MIA; R. A. Dixon, D. F. Hultsch, & C. Hertzog, 1988; C. Hertzog, D. F. Hultsch, & R. A. Dixon, 1989; R. W. H. M. Ponds & J. Jolles, 1996). The total MSE score predicted memory performance at 6 years, as measured by the Visual Verbal Learning Task (VVLT; N. Brand & J. Jolles, 1985). A separate analysis of the different MSE subscales indicated that the MIA Change score was the most salient domain-specific MSE predictor of subsequent memory performance after 6 years. An extreme groups analysis of the MIA Change score revealed a pattern of performance for those who perceived that their memory was worsening, performing less well on the 3 trials of the VVLT when these were readministered at the 6-year follow-up. PMID:16594801

Valentijn, Susanne A M; Hill, Robert D; Van Hooren, Susan A H; Bosma, Hans; Van Boxtel, Martin P J; Jolles, Jelle; Ponds, Rudolf W H M

2006-03-01

114

Long-term follow-up study on patients with vibration-induced white finger (VWF).  

PubMed

The prognosis of vibration-induced white finger was investigated with a long follow-up period. From 1975 to 1994, 99 men with hand-arm vibration syndrome who received the annual compulsory examination at San-in Rosai Hospital were followed up for 15 years or longer. Based on the extent of finger-blanching attacks described in the medical records, they were classified according to the vascular stage of the Stockholm workshop scale. In our laboratory, finger systolic blood pressure (FSBP) measurement after finger cooling has been performed since 1989. We compared the stage classification with the results of FSBP measurement after finger cooling in the period 1989-1994. The stage 2 and stage 3 groups showed a significant decrease in FSBP% compared with the stage 0 group. The vascular stage classification based on subjective symptoms in this study was to a certain extent reliable. Although vibration-induced white finger symptoms tended to improve to some extent, 43.2% and 70.4% of patients with stage 2 and stage 3 at first examination, respectively, still suffered from finger blanching attacks after 15 years of observation. Blanching of fingers in advanced stages, especially stage 3, was found to be persistent many years after cessation of vibration exposure. PMID:12500465

Kurozawa, Youichi; Nasu, Yoshiro; Hosoda, Takenobu; Nose, Takayuki

2002-12-01

115

Motor development in children at risk of autism: a follow-up study of infant siblings.  

PubMed

Recently, evidence of poor or atypical motor skills in autism spectrum disorder has led some to argue that motor impairment is a core feature of the condition. The current study uses a longitudinal prospective design to assess the development of motor skills of 20 children at increased risk of developing autism spectrum disorder, who were recruited and tested at 9 and 40 months of age, on the basis of having an older sibling diagnosed with the condition. All children completed a range of motor, face processing, IQ and diagnostic assessments at a follow-up visit (aged 5-7 years), providing a detailed profile of development in this group from a number of standardised, parental report and experimental measures. A higher proportion of children than expected demonstrated motor difficulties at the follow-up visit and those highlighted by parental report as having poor motor skills as infants and toddlers were also more likely to have lower face processing scores and elevated autism-related social symptoms at 5-7 years, despite having similar IQ levels. These data lend support to the argument that early motor difficulties may be a risk factor for later motor impairment as well as differences in social communication and cognition, traits that are related to autism spectrum disorder. PMID:24101718

Leonard, Hayley C; Bedford, Rachael; Charman, Tony; Elsabbagh, Mayada; Johnson, Mark H; Hill, Elisabeth L

2014-04-01

116

Gallbladder Stones Following Ileal Resection for Gangrenous Intussusceptions: A Follow-up Study  

PubMed Central

Background: Intussusceptions are the most common causes of bowel obstruction in infancy and childhood in this environment they present late, resulting in gangrene of the intussusception consequently resection of the affected bowel and a limited or extended right hemicolectomy (RH) to establish bowel continuity. Aim: The aim of the following study is to follow-up these children that had a limited ileal resection for gangrenous intussusceptions and document the formation of stones in their gallbladders. Materials and Methods: A total of 14 patients who had limited ileal resection during infancy for gangrenous intussusceptions were matched with sixteen patients who had manual reduction for viable intussusceptions during infancy. Both groups had ultrasound scans of their gallbladders to document the formation of stones in their gallbladders. Results: No gallbladder stones were found in both groups, however, one male child that had a resection and a RH for a gangrenous intussusception at the age of 4 months and was seen at an interval of 72 months had a thickened gallbladder on ultrasonography, another child, a female child operated on at the age of 6 months and seen at an interval of 57 months also had a thickened gallbladder on ultrasonography. Conclusion: Although no stones were seen, we suggest a prolonged follow-up of these patients with either periodic ultrasonography of the their gallbladders or with the periodic estimation of their serum bile acids. PMID:24665197

Osuoji, Roland Iheanyichukwu; Balogun, Babajide Olawale; Olofinlade, Olatunbosun Olabode

2014-01-01

117

Follow-Up Study in Head and Neck Cancer: Cure Rate according to Tumor Location and Stage  

Microsoft Academic Search

The purpose of this clinical study was to analyze a long-term follow-up of all the patients with head and neck cancer in our institution. Between 1973 and 1993,1,355 consecutive cases of head and neck cancer were diagnosed, treated and followed up regularly. All were subjected to a multidisciplinary approach, and followed up until death or for 10 years with no

Juan J. Grau; Asunción Cuchi; José Traserra; José L. Fírvida; Carlos Arias; José L. Blanch; Jordi Estapé

1997-01-01

118

Effect of Safe Water on Arsenicosis: A Follow-up Study  

PubMed Central

Background: Arsenic pollution in groundwater, used for drinking purposes, has been envisaged as a problem of global concern. Treatment options for the management symptoms of chronic arsenicosis are limited. Mitigation option available for dealing with the health problem of ground water arsenic contamination rests mainly on supply of arsenic safe water in arsenic-endemic region of Indo-Bangladesh subcontinent. Limited information is available regarding the long-term effect of chronic arsenic toxicity after stoppage of consumption of arsenic-containing water. Objective: The current study was, therefore, done to assess, objectively, the effect of drinking arsenic safe water (<50 ?g/L) on disease manifestation of arsenicosis. Results: Manifestations of various skin lesions and systemic diseases associated with chronic arsenic exposure were ascertained initially by carrying on baseline study on 208 participants in Nadia (Cohort-I, with skin lesion and Cohort-II, without skin lesion) using a scoring system, as developed by us, and compared objectively at the end of each year for 3 year follow-up period. All the participants who had arsenic contaminated drinking water source in their houses were supplied with arsenic removal filters for getting arsenic-free water during the follow-up period. In participants belonging to Cohort-I, the skin score was found to improve significantly at the end of each year, and it was found to be reduced significantly from 2.17 ± 1.09 to 1.23 ± 1.17; P < 0.001 at the end of 3 year's intervention study indicating beneficial effect of safe water on skin lesions. The systemic disease symptom score was also found to improve, but less significantly, at the end of 3 years in both the cohorts. Most important observation during the follow-up study was persistence of severe symptoms of chronic lung disease and severe skin lesion including Bowen's disease in spite of taking arsenic-safe water. Further, death could not be prevented to occur because of lung cancer and severe lung disease. Conclusion: It is, therefore, an urgent need to make arrangement for availability of safe water source among the arsenic-affected people in the district. Many of the people in the affected villages are not aware of contamination of their home tube wells with arsenic. Awareness generation and motivation of the people for testing their drinking water sources for arsenic and environmental interventions like rain water harvesting, ground water recharge, and restricting excessive use of ground water for domestic and agricultural purposes are also important to prevent further exposure of arsenic to these people. PMID:25161968

Majumdar, Kunal K.; Ghose, Aloke; Ghose, Nilima; Biswas, Anirban; Mazumder, D.N. Guha

2014-01-01

119

Follow-up study of patients treated for ingrown nails with the nail matrix phenolization method.  

PubMed

In the past 7 years, a total of 537 ingrown nail lesions were treated with the nail matrix phenolization method (NMP). A study was performed based on follow-up examinations and a questionnaire survey regarding recurrence rate, degree severity, duration of postoperative pain, and other relevant factors. The major advantages of the NMP revealed by our study were: (1) The surgical procedure is easy to perform and does not require specialized equipment; (2) total time requirement for surgery is minimal; (3) the operation can be performed in the presence of a concomitant infection; (4) the recurrence rate is low (1.1%); and (5) postoperative pain and postoperative bed rest is minimized. These results indicate that NMP is an extremely effective method for treatment of ingrown nails. PMID:7892317

Kimata, Y; Uetake, M; Tsukada, S; Harii, K

1995-04-01

120

What Affects Reintegration of Female Drug Users after Prison Release? Results of a European Follow-Up Study  

ERIC Educational Resources Information Center

The main objective of this follow-up study is to explore factors influencing the success or failure of women in reintegrating after their release from prison. Female drug users in five European cities were tracked after being released from prison. Out of 234 female prisoners contacted in prisons, 59 were included in the follow-up study. Structured…

Zurhold, Heike; Moskalewicz, Jacek; Sanclemente, Cristina; Schmied, Gabriele; Shewan, David; Verthein, Uwe

2011-01-01

121

75 FR 70365 - Agency Information Collection (Follow-Up Study of a National Cohort of Gulf War and Gulf Era...  

Federal Register 2010, 2011, 2012, 2013, 2014

...refer to ``OMB Control No. 2900-New...INFORMATION: Titles: Follow-Up Study of a National...10-0488a. OMB Control Number: 2900-New...unexplained multi-system illnesses. VA...currently valid OMB control number. The...Burden: a. Follow-Up Study of a...

2010-11-17

122

Education Longitudinal Study of 2002 (ELS:2002) Third Follow-up Data File Documentation. NCES 2014-364  

ERIC Educational Resources Information Center

This report provides guidance and documentation for users of the combined base-year to third follow-up data of the Education Longitudinal Study of 2002 (ELS:2002). ELS:2002 is sponsored by the National Center for Education Statistics (NCES) of the Institute of Education Sciences, U.S. Department of Education. The base-year and follow-up studies

Ingels, Steven J.; Pratt, Daniel J.; Alexander, Christopher P.; Jewell, Donna M.; Lauff, Erich; Mattox, Tiffany L.; Wilson, David

2014-01-01

123

U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--FOOD FOLLOW-UP QUESTIONNAIRE DATA  

EPA Science Inventory

The Food Follow-up Questionnaire data set provides information on the eating patterns and the food identification and preparation methods that occurred during the period the food sample was taken. The information is for 86 Food Follow-up Questionnaires for 86 households. In the...

124

The sexual struggles of 23 clergymen: A follow-up study  

Microsoft Academic Search

Nineteen clergymen, 17 of whom were Catholic, were followed up 1 to 6 years after their initial evaluation in a program designed to assess the sexual offenses and rehabilitation potential of offending professionals. Methods used included a semistructured interview with a research psychiatrist and a repeat of the MCMI-III. At follow-up, the clergymen were relatively psychologically healthy. The vast majority

Calvin S. L. Fones; Stephen B. Levine; Stanleye Althof; Candace B. Risen

1999-01-01

125

Myopia and Myopic Progression Among Schoolchildren: A Three-Year Follow-Up Study  

Microsoft Academic Search

Purpose. To discuss the factors that might explain the rate of myopic progression and the degree of myopia after a 3-year follow-up among schoolchildren with myopia. Methods. Myopic progression among 238 schoolchildren was followed up in a randomized clinical trial of myopia treatment. The associations between the explanatory factors and myo- pic progression and the final value of the spherical

Olavi Pcirssinen; Anna-Liisa Lyyraf

1993-01-01

126

Recruiting Adolescent Girls into a Follow-up Study: Benefits of Using a Social Networking Website  

PubMed Central

Background Recruitment and retention of adolescent research participants presents unique challenges and considerations when conducting epidemiological studies. Purpose To describe the use of the social networking website in the re-recruitment and tracking of adolescent girls into a follow-up study of the Trial of Activity for Adolescent Girls (TAAG) at the University of Maryland field site. Methods 730 girls were recruited as 8th graders into TAAG. Re-recruitment efforts were conducted when they were 11th graders (TAAG 2). Traditional methods, including mailings and school visits, were conducted. A TAAG 2 Facebook site was created to search for girls not found through traditional recruitment methods. Chi-square and t-tests were conducted to identify differences in characteristics between those found and “friended” through Facebook and through traditional recruitment methods. Results There were 175 girls we were unable to locate using traditional recruitment methods. Of these, 78 were found on Facebook, 68 responded to our friend request, and 43 girls (6% of the girls previously recruited) participated in the study. Demographic data were similar for those who friended us on Facebook and traditional methods. 8th grade body mass index and percent body fat were lower for those recruited from Facebook (p = 0.03 and 0.04, respectively). Number of daily minutes of moderate-to-vigorous physical activity tended to be lower among the TAAG 2 Facebook friends (19 ± 11 vs 21 ± 11, p = 0.06). Conclusions Loss to follow-up was minimized by contacting potential participants through Facebook. Social networking websites are a promising method to recruit adolescents. PMID:22101207

Jones, Lindsey; Saksvig, Brit I.; Grieser, Mira; Young, Deborah Rohm

2011-01-01

127

Successful careers and cognitive style: a follow-up study of childhood family discontinuity.  

PubMed

It was predicted that those participants who experienced discontinuity (death, divorce, and separations) from their parent(s) in childhood and who had successful careers in adulthood would manifest more innovative than adaptive cognitive styles on the Kirton Adaption-Innovation Inventory. The original research showed 61% of the sample members (n = 41) experienced family discontinuity. Ninety percent (n = 37) of the previous participants responded and showed 59% family discontinuity. Fifty-four percent in the follow-up study chose an alternative career path (counterstriving), the same percentage as in the original sample. When both family discontinuity and counterstriving were present, statistically significant innovation scores occurred. Family discontinuity in childhood and a successful career in adulthood are likely to be associated with high striving-motivation and an innovative (paradigm-breaking) problem-solving style. PMID:1792271

Gordon, V Z

1991-12-01

128

Comparison of hospice use by European americans, african americans, and latinos: a follow-up study.  

PubMed

This study investigated the rate of hospice use by Latinos and African Americans relative to their prevalence in the general population between 2004 and 2010 as a follow-up to a previous investigation. Archival data (N = 2625) were collected on patients' race/ethnicity, gender, marital status, length of stay in hospice, and reason for discharge. In contrast to previous findings, African Americans were more likely to utilize hospice services, but Latinos were less likely to use hospice services compared to the other groups. There were no differences among the racial/ethnic groups in terms of length of stay or disposition at termination. Strengthening efforts to reach a larger racial/ethnic representation in hospice programs may increase the rate of hospice use by some racial/ethnic groups but not others. PMID:24219885

Colón, Merydawilda; Lyke, Jennifer

2015-03-01

129

Evaluation of Clinical Outcomes for Gastric Bypass Surgery: Results from a Comprehensive Follow-up Study  

Microsoft Academic Search

Background  Laparoscopic gastric bypass (LGB) surgery markedly increases percent excess weight loss (%EWL) and obesity-related co-morbidities.\\u000a However, poor study quality and minimal exploration of clinical, behavioral, and psychosocial mechanisms of weight loss have\\u000a characterized research to date.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  We conducted a comprehensive assessment of n=100 LGB patients surveyed 2–3 years following surgery using standardized measures.\\u000a \\u000a \\u000a \\u000a \\u000a Results  Mean %EWL at follow-up was 59.1±17.2%. This

Garry Welch; Cheryl Wesolowski; Sofija Zagarins; Jay Kuhn; John Romanelli; Jane Garb; Nancy Allen

2011-01-01

130

Prevalence of celiac disease in Germany: A prospective follow-up study  

PubMed Central

AIM: To determine the prevalence of celiac disease in a randomly selected population sample. METHODS: A total of 2157 subjects (1036 males; 1121 females) participating in a population-based cross-sectional study underwent laboratory testing for tissue transglutaminase and antibodies to immunoglobulin A, endomysium and antigliadin. In a second step, all subjects who had been examined serologically were surveyed using a questionnaire that included questions specific to celiac disease. Subjects with positive antibody titers and those with histories positive for celiac disease then underwent biopsy. At the first follow up, antibody titers were again determined in these subjects and subjects were questioned regarding symptoms specific for celiac disease and disorders associated with celiac disease. The second follow up consisted of a telephone interview with subjects positive for celiac disease. RESULTS: Antibody tests consistent with celiac disease were reported in eight subjects, corresponding to an overall prevalence of 1:270 (8/2157). The prevalence among women was 1:224 and 1:518 in men. Classical symptoms were observed in 62.5% of subjects. Atypical celiac disease was present in 25.0%, and transient celiac disease in 12.5%. False-negative test results were returned in three subjects. This yields a sensitivity and specificity of 62.5% and 50.0%, respectively, for tissue transglutaminase immunoglobulin-A antibody; of 62.5% and 71.4% respectively, for endomysium antibody; and of 62.5% and 71.4%, respectively, for antigliadin antibody. CONCLUSION: The prevalence rate in our collective lies within the middle tertile of comparable studies in Europe. The use of a single antibody test for screening purposes must be called into question. PMID:23674868

Kratzer, Wolfgang; Kibele, Monika; Akinli, Atilla; Porzner, Marc; Boehm, Bernhard O; Koenig, Wolfgang; Oeztuerk, Suemeyra; Mason, Richard A; Mao, Ren; Haenle, Mark H

2013-01-01

131

Clinical profile and follow-up of 51 pediatric neurocysticercosis cases: A study from Eastern India  

PubMed Central

Introduction: Our present observational study attempted to evaluate the clinical profiles, diagnosis, treatment and follow-up results of 51 pediatric neurocysticercosis patients over a mean duration of five years (from January 2006 to December 2010). Materials and Methods: Diagnosis was mainly based on clinical features, computed tomography (CT)/magnetic resonance imaging scan and exclusion of other causes. Patients with active, transitional cysts and seizure were treated with albendazole for 28 days, steroids and anticonvulsants. Results: A total of 38 patients completed this study. Mean age of the presentation was 8.47 ± 3.19 years 52.6% of the patients were female. Overall patients presented with generalized seizure in 55.3%, focal in 31.6%, headache ± vomiting in 63.2%, focal neurodeficit in 10.5% and combination of symptoms in 60.5% cases. Contrast CT brain showed a solitary lesion in 27 (71.1%) and multiple in the rest. At presentation lesions were transitional in 58.2%, inactive in 20% and mixed in 14.6%. After a mean of 2 years, seizure persisted in 9 (23.7%) and headache in 8 (21.1%) of whom six had normal electroencephalography (EEG) while one each showed focal slowing, generalized slowing and epileptiform discharges. During the follow-up, CT scan brain 44.7% lesions calcified, 31.6% disappeared, 10.5% regressed and the rest persisted. Conclusion: Solitary ring enhancing lesions (transitional stage) involving the parietal lobe was the commonest CT picture at presentation. Generalized tonic-clonic seizure was the most common type of seizure. Number of lesions, persistence of lesion, number of seizures, EEG abnormality at presentation were not found to be prognostically significant (P > 0.05). PMID:24339577

Bhattacharjee, Shakya; Biswas, Prativa; Mondal, Tanushree

2013-01-01

132

Relationships in couples treated with sperm donation - a national prospective follow-up study  

PubMed Central

Background Long-term follow-up on relationship quality in couples who use sperm donation is scarce. Therefore, this study aimed to analyse changes over time in satisfaction with relationship in heterosexual couples who were scheduled for treatment with sperm donation and IVF couples treated with their own gametes and to compare the two groups undergoing different treatment for infertility. Method A prospective follow-up study in which data were collected twice on two groups; couples receiving sperm donation and IVF couples using their own gametes. The ENRICH instrument was used to gain information about the individuals’ subjective experience of their relationship at the time of acceptance for treatment and again 2–5 years later. Results At the time of acceptance for treatment the men and women in the two groups assessed their relationships as being very solid on all dimensions and that there were no differences between the two groups. At the second assessment there was a decline in the satisfaction scores on the dimensions “Children and parenting” and “Egalitarian”, while an increase in scores was observed on “Conception of life” and “Conflict resolution” both for men and woman and also for the two groups. For the couples that had a successful treatment and gave birth to a child/children there was a decrease in satisfaction of the relation in the sperm donation group as well as in the group of couples having IVF with own gametes. Conclusion In conclusion, the overall quality of relationship is stable in couples receiving donated sperm and does not differ from couples undergoing IVF-treatment with own gametes. PMID:25100133

2014-01-01

133

Childhood Predictors of Male Criminality: A Prospective Population-Based Follow-up Study from Age 8 to Late Adolescence  

ERIC Educational Resources Information Center

Objective: To study childhood predictors for late adolescence criminality. Method: The follow-up sample included 2,713 Finnish boys born in 1981. Information about the 8-year-old boys' problem behavior was obtained from parents, teachers, and the children themselves. The follow-up information about criminal offenses was based on the national…

Sourander, Andre; Elonheimo, Henrik; Niemela, Solja; Nuutila, Ari-Matti; Helenius, Hans; Sillanmaki, Lauri; Piha, Jorma; Tamminen, Tuula; Kumpulainen, Kirsti; Moilanen, Irma; Almqvist, Frederik

2006-01-01

134

Clinical experience of marketed Levetiracetam in an epilepsy clinic—a one year follow up study  

Microsoft Academic Search

Levetiracetam is a new anti-convulsant with impressive pivotal trial credentials. We examined its effectiveness in refractory clinic patients with epilepsy with a year’s follow up. Six months after initiation 32% of the patients were seizure free, and 26% at one year.By the end of the 12 months follow up 77% of patients were still taking the drug, having gained benefit

TIM BETTS; HELEN YARROW; LYN GREENHILL; MARY BARRETT

2003-01-01

135

A Prospective Controlled Study of Kidney Donors: Baseline and 6-Month Follow-up  

PubMed Central

Background Most previous studies of living kidney donors have been retrospective and have lacked suitable healthy controls. Needed are prospective controlled studies to better understand the effects of a mild reduction in kidney function from kidney donation in otherwise normal individuals. Study Design Prospective, controlled, observational cohort study. Setting & Participants Consecutive patients approved for donation at 8 transplant centers in the US were asked to participate. For every donor enrolled, an equally healthy control with 2 kidneys who theoretically would have been suitable to donate a kidney was also enrolled. Predictor Kidney donation. Measurements At baseline pre-donation and at 6 months after donation, a medical history, vital signs, measured (iohexol) glomerular filtration rate and other measurements were collected. There were 201 donors and 198 controls that completed both baseline and 6 month visits and form the basis of this report. Results Compared to controls, donors had 28% lower glomerular filtration rate at 6 months (94.6±15.1 [SD] v. 67.6±10.1 mL/min/1.73m2; P<0.001), associated with a 23% greater parathyroid hormone (42.8±15.6 v. 52.7±20.9 pg/mL; P<0.001), 5.4% lower serum phosphate (3.5±0.5 v. 3.3±0.5 mg/dL; P<0.001), 3.7% lower hemoglobin (13.6±1.4 v. 13.1±1.2 g/dL; P<0.001), 8.2% greater uric acid (4.9±1.2 v. 5.3±1.1 mg/dL; P<0.001), 24% greater homocysteine (1.20±0.34 v. 1.49±0.43 mg/L; P<0.001), and 1.5% lower high density lipoprotein cholesterol (54.9±16.4 v. 54.1±13.9 mg/dL; P=0.03) level. There were no differences in albumin-creatinine ratios (5.0 [IQR, 4.0-6.6] v. 5.0 [IQR, 3.3-5.4] mg/g; P=0.5), office blood pressure, or glucose homeostasis. Limitations Short duration of follow-up and possible bias resulting from an inability to screen controls with kidney and vascular imaging performed in donors. Conclusions Kidney donors have some, but not all, abnormalities typically associated with mild chronic kidney disease 6 months after donation. Additional follow up is warranted. PMID:23523239

Kasiske, Bertram L.; Anderson-Haag, Teresa; Ibrahim, Hassan N.; Pesavento, Todd E.; Weir, Matthew R.; Nogueira, Joseph M.; Cosio, Fernando G.; Kraus, Edward S.; Rabb, Hamid H.; Kalil, Roberto S.; Posselt, Andrew A.; Kimmel, Paul L.; Steffes, Michael W.

2013-01-01

136

Relationships in oocyte recipient couples – a Swedish national prospective follow-up study  

PubMed Central

Background The long-term effect of treatment with donated oocytes on women’s and men’s perception of their relationship has been little studied. Thus the aim of this study was to analyse satisfaction with relationships in couples at the time of acceptance for treatment and 2–5 years after treatment with donated gametes and to compare them with IVF couples treated with their own gametes. Method A prospective follow-up study in which data were collected twice on two groups; cohabitating couples receiving oocyte donation and cohabitating IVF couples using their own gametes. A standardised instrument, the ENRICH inventory, was used to gain information about the couples’ subjective experience of their relationships. Results At acceptance for treatment the couples in the two groups assessed their relationships as being very solid on all dimensions and that the women receiving treatment with oocyte showed a higher satisfaction compared to women treated with own gametes. For couples that did have a child, the group of women who had been through the oocyte donating program reported a better quality of their relationship than women in the control group. There were no significant differences in perceived relationship quality between men in the different groups, whether they had a child or not. Conclusions From a long-term perspective couples using oocyte donation treatment have a balanced and solid view of their relationship and treatment, having children or not after treatment did not affect the nature of the relationships. PMID:24885541

2014-01-01

137

Follow-up studies after withdrawal of deltamethrin spraying against Anopheles culicifacies and malaria incidence.  

PubMed

Follow-up studies were carried out from 1989 to 1998 after withdrawal of deltamethrin indoor spraying to evaluate the recovery rate of a population of Anopheles culicifacies resistant to dichlorodiphenyltrichloroethane (DDT) and hexachlorocyclohexane (HCH) in selected villages in Uttar Pradesh State, India. The study revealed 82.4-96.5% reduction in adult density of An. culicifacies and 72.7-96% reduction in malaria incidence in the area sprayed with deltamethrin at 20 mg/m2 as compared to a control area sprayed with HCH, for 5 successive years even after withdrawal of deltamethrin spray. The impact was very clear when the annual falciparum incidence was compared with that of the control area. The vector population gradually started recovering after 5 years. However, the slide falciparum rate remained below 4 even after 10 years of withdrawal of spraying. The study revealed that indoor residual spraying of deltamethrin would be cost-effective, at least in areas where malaria is transmitted by An. culicifacies, which is primarily a zoophilic species and associated with malaria epidemics. In view of this, a review of the insecticide policy and strategy of vector control is urgently needed because of the possible risks associated with the presence of nonbiodegradable insecticide in the environment, as well as to minimize the costs of operation and to enhance the useful life of insecticides. PMID:15669385

Ansari, Musharraf Ali; Razdan, Rama Krishna

2004-12-01

138

Parents' evaluation of adoption success: a follow-up study of intercountry and domestic adoptions.  

PubMed

Parents of 165 children adopted from Romania and 52 children adopted from within the United Kingdom rated the success of the adoptions when the children were 11 years old. As was the case at two earlier study waves, satisfaction was found to be extremely high. Both positive and negative assessments were generally stable between ages 6 and 11, although for the children who had more problems there was an increase in negative evaluation, albeit within an overall positive picture. Parents' evaluations were somewhat more negative for this group of children; however, parents reported that having the child as part of their family was very rewarding. Negative evaluation was not directly related to age at placement, but appeared to be a reflection of the later-placed children's higher rates of problem behavior. As found at earlier assessment waves, child factors, in particular conduct problems and inattention or overactivity, were key in predicting parental evaluations at age 11, as were four domains closely associated with institutional deprivation, namely cognitive impairment, quasi-autistic patterns, inattention or overactivity, and disinhibited attachment. The findings emphasize the need for early intervention for children in severely deprived conditions, and for access to postadoption services that target the particular problem behaviors the children may exhibit. PMID:20099943

Castle, Jenny; Groothues, Christine; Beckett, Celia; Colvert, Emma; Hawkins, Amanda; Kreppner, Jana; Kumsta, Robert; Schlotz, Wolff; Sonuga-Barke, Edmund; Stevens, Suzanne; Rutter, Michael

2009-10-01

139

A prospective follow-up study on transmission of campylobacter from poultry to abattoir workers.  

PubMed

Contact with poultry or poultry meat is a well-known risk factor for campylobacteriosis, but prospective studies on transmission of Campylobacter from chickens to humans during slaughter are scarce. In this study, we monitored transmission of Campylobacter from slaughtered chicken to originally culture-negative abattoir workers during the peak season of colonized chicken and human Campylobacter infection. Stool samples were obtained from 28 abattoir workers together with data on health status once a month between June and September 2010, with a follow-up sample collected in February 2011. Campylobacter-positive individuals and chicken flocks were identified by culture, and isolates were further characterized using molecular techniques. Campylobacter was isolated from seven asymptomatic individuals. Four of them had been newly employed and had not reported any previous Campylobacter infection. Four human isolates had matching genetic fingerprints with isolates from recently slaughtered chickens. Our results further support the role of chicken as the source of human Campylobacter infection but suggest that asymptomatic Campylobacter infection may occur even in individuals with only limited earlier exposure to Campylobacter. PMID:24885791

Ellström, Patrik; Hansson, Ingrid; Söderström, Claes; Engvall, Eva Olsson; Rautelin, Hilpi

2014-09-01

140

Juvenile Hemochromatosis, Genetic Study and Long-term Follow up after Therapy  

PubMed Central

BACKGROUND Hereditary hemochromatosis (HH) is a very rare disease in Iran and reported cases are all negative for HFE mutation. We report a family affected by severe juvenile hemochromatosis (JH) with a detailed molecular study of the family members. METHODS We studied a pedigree with siblings affected by juvenile HH and followed them for 3 years. Microsatellite and gene sequencing analysis was performed for all family members. RESULTS Two siblings (the proband and his sister, aged 26 and 30 years, respectively) were found to have clinical findings of JH. The proband’s brother, who presented with hyperpigmentation, died of probable JH at the age of 24 years. Gene sequencing analysis showed that the proband has a homozygote c.265T>C (p.C89R) HJV mutation + a heterozygote c.884T>C (p.V295A) mutation of HFE. The affected proband’s sister presented with the same HJV c.265T>C (p.C89R) homozygote mutation. In addition, we found the HJV c.98-6C>G polymorphic variant in both the sister and proband (homozygote). Sequencing of hepcidin (HAMP), TfR2, and FPN revealed no mutation. CONCLUSION We have shown that molecular analysis of the HH related gene is a powerful tool for reliable diagnosis of JH and, in conjunction with magnetic resonance imaging (MRI) and noninvasive liver stiffness measurement by elastography, is adequate tool for management and follow up of HH. PMID:24872867

Malekzadeh, Masoud M.; Radmard, Amir Reza; Nouroozi, Alireza; Akbari, Mohammad Reza; Amini, Marzie; Navabakhsh, Behrooz; Caleffi, Angela; Pietrangelo, Antonello; Malekzadeh, Reza

2014-01-01

141

Radioactive iodine therapy and breast cancer. A follow-up study of hyperthyroid women  

SciTech Connect

A follow-up study of 1762 hyperthyroid women who were treated at the Massachusetts General Hospital Thyroid Unit between 1946 and 1964 was conducted. The average length of follow-up was 17.2 years. A 1978 mailing address or a death certificate was located for 92% of the women, and 88% of 1058 living patients responded to a mail questionnaire. The standardized mortality ratio (SMR) for all causes of death was 1.3 (95% confidence interval (CI) 1.2-1.4). The standardized mortality ratios for all malignant neoplasms and for breast cancer were 0.9 (95% CI 0.7-1.1) and 1.3 (95% CI 0.8-1.9), respectively. More deaths than expected were observed from endocrine and metabolic diseases (SMR = 1.8, 95% CI 1.2-2.7), circulatory system diseases (SMR = 1.4, 95% CI 1.3-1.6), and respiratory system diseases (SMR = 1.9, 95% CI 1.3-2.6). The standardized incidence ratios (SIR) for all malignant neoplasms and for breast cancer were 0.9 (95% CI 0.8-1.1) and 1.2 (95% CI 0.9-1.5), respectively. A nonsignificant excess breast cancer risk was observed 10 years after the onset of thyroid symptoms and was present at the end of 30 years of observation. A statistically significant excess number of pancreatic cancer cases (SIR = 2.0, 95% CI 1.0-3.7) and a nonsignificant excess of brain cancer cases (SIR = 2.3, 95% CI 0.7-5.3) were observed. Eighty per cent of the women were treated with radioactive iodine. When age at treatment and year of treatment were controlled, women who were ever treated with radioactive iodine had a standardized rate ratio for breast cancer of 1.9 (95% CI 0.9-4.1), compared with those who were never treated with radioactive iodine. Women who developed hypothyroidism as a result of their treatment for hyperthyroidism did not have an increased risk of developing breast cancer (SIR = 1.1, 95% CI 0.8-1.6).

Goldman, M.B.; Maloof, F.; Monson, R.R.; Aschengrau, A.; Cooper, D.S.; Ridgway, E.C.

1988-05-01

142

Study Factors Influencing Ventricular Enlargement in Schizophrenia: A 20 Year Follow-Up Meta-Analysis  

PubMed Central

A meta-analysis was performed on studies employing the ventricular-brain ratio to compare schizophrenic subjects to that of normal controls. This was a follow-up to a similar meta-analysis published in 1992 in which study-, in addition to clinical-, factors were found to contribute significantly to the reported difference between patients with schizophrenia and controls. Seventy-two (N=72) total studies were identified from the peer reviewed literature, 39 from the original meta-analysis, and 33 additional studies published since which met strict criteria for inclusion and analysis– thus representing ~30 years of schizophrenia ventricular enlargement research. Sample characteristics from schizophrenics and controls were coded for use as predictor variables against within sample VBR values as well as for between sample VBR differences. Additionally, a number of factors concerning how the studies were conducted and reported were also coded. Obtained data was subjected to unweighted univariate as well as multiple regression analyses. In particular, results indicated significant differences between schizophrenics and controls in ventricular size but also the influence of the diagnostic criteria used to define schizophrenia on the magnitude of the reported VBR. This suggests that differing factors of the diagnostic criteria may be sensitive to ventricular enlargement and might be worthy of further examination. Interestingly, we observed an inverse relationship between VBR difference and the number of co-authors on the study. This latter finding suggests that larger research groups report smaller VBR differences and may be more conservative or exacting in their research methodology. The diagnostic criteria used for defining schizophrenia were also predictive of between group differences. Analyses weighted by sample size provided identical conclusions. The effects of study factors such as these are helpful for understanding the variation in the size of the reported differences in VBR between patients and controls as well as for understanding the evolution of research on complex clinical syndromes employing neuroimaging morphometrics. PMID:21787868

Sayo, Angelo; Jennings, Robin G.

2012-01-01

143

Personality as a predictor of depression symptoms in burn patients: A follow-up study.  

PubMed

There is empirical evidence that having some personality characteristics increases the risk of developing depression. This is the first study which analyses the role of personality dimensions, assessed by the Alternative Five Factor Model, in the development of depressive symptoms in adult burn survivors across time. Participants were 109 adult burn survivors admitted to a Burns Unit. Personality was assessed by the Zuckerman-Kuhlman Personality Questionnaire and depression symptoms by the Beck Depression Inventory. After adjusting by age, gender and burn size, results showed that high Neuroticism-Anxiety (N-Anx) and Aggression-Hostility (Agg-Host) were related to higher depression scores when compared with low N-Anx and Agg-Host groups along the six months follow-up. Moreover, Activity and Impulsive-Sensation Seeking factors were involved in statistically significant different depressive symptom development trajectories during the six months after burn. These findings suggest that personality factors could be used to identify the most vulnerable patients, who could develop severe mood symptoms at different points in their recovery. PMID:25145874

Giannoni-Pastor, A; Gomà-I-Freixanet, M; Valero, S; Fidel Kinori, S G; Tasqué-Cebrián, R; Arguello, J M; Casas, M

2015-02-01

144

Silica exposure and rheumatoid arthritis: a follow up study of granite workers 1940-81.  

PubMed Central

The incidence and prevalence of subjects awarded disability pensions and the prevalence of subjects receiving free medicines because of rheumatoid arthritis were studied in a Finnish cohort of 1026 granite workers hired between 1940 and 1971 and followed up until 31 December 1981. The incidence of awards of disability pensions because of rheumatoid arthritis during 1969-81, the prevalence of rheumatoid arthritis on 31 December 1981, and the prevalence of subjects receiving free medicines for rheumatoid arthritis at the end of 1981 were significantly higher among the granite workers than in the general male population of the same age. Retrospective analysis of the records of all patients with rheumatoid arthritis in the cohort showed a predominance of a severe, serologically positive and erosive form of rheumatoid arthritis, usually with an age at onset of 50 or over. The possible aetiological or pathophysiological role of granite dust in rheumatoid arthritis may be based on the effects of quartz on the immune system. PMID:2823951

Klockars, M; Koskela, R S; Järvinen, E; Kolari, P J; Rossi, A

1987-01-01

145

Inpatient treatment of functional motor symptoms: a long-term follow-up study.  

PubMed

Functional neurological disorders are common, disabling and often difficult to treat. There is little consensus on the best approach to management. Multidisciplinary inpatient approaches are employed in some centres for patients with severe refractory symptoms, but their efficacy and, in particular, long-term outcomes are uncertain. We conducted a study using questionnaires completed retrospectively by patients treated at a specialised multidisciplinary inpatient programme at the National Hospital for Neurology and Neurosurgery. Consecutive patients with functional motor symptoms admitted to this centre between 2006 and 2008 were invited to participate. Questionnaires were sent at least 2 years after discharge. We contacted 32 patients, and 26 responded. The majority had symptoms for at least 3 years prior to admission; 58 % of patients reported benefit from the programme on discharge. This self-reported benefit to symptoms and function was after a 2-year follow-up period in the majority of patients, but return to work or cessation of health-related financial benefits was uncommon even in those who improved. Seventy-four percent of those questioned stated they would recommend the programme to others with similar symptoms. Attribution of symptoms to stress or emotional state was correlated with favourable outcome. Our data suggest that multidisciplinary inpatient treatment for patients with refractory functional motor symptoms provides self-reported benefit in the long-term. Prospective analysis of such interventions and the determinants of benefit need assessment in order to improve the service and target treatment to patients most likely to benefit. PMID:22584953

Saifee, T A; Kassavetis, P; Pareés, I; Kojovic, M; Fisher, L; Morton, L; Foong, J; Price, G; Joyce, E M; Edwards, M J

2012-09-01

146

Follow-up study of lympho-histiocytic villitis and incidental retroplacental hematoma.  

PubMed

Placentas are usually submitted for pathologic examination based on obstetrical indications. We hypothesized that the placenta may have diagnostic value to the infant independent of obstetrical events. We specifically tested whether lymphohistiocytic villitis (noninfectious) would predict autoimmune or alloimmune disease based on transfer of activated maternal T-cells to the fetus and whether clinically silent placental separations (retroplacental hematomas, RPH) would predict neurologic injury in the infant. All placentas from consecutive deliveries had a routine pathologic examination of the placenta. The infants with placentas demonstrating inflammation of >1% of villi or RPH >2 cm and matched controls had their hospital charts reviewed and parental interviews by telephone at 5 to 7 years of age. The children of consented patients were also searched for in the office visits of the University of Louisville Pediatric Neurology and Rheumatology divisions. One thousand six hundred eighty-four patients consented to the follow-up study. We found no cases of autoimmune disease among 17 children with villitis >1%. Of 16 infants with RPH, 1 had cerebral palsy but with other placental findings, 1 had lethal hydranenecephaly, and the remainder had no adverse outcome. Of 15 children seen by a pediatric neurologist, none had the same placental lesion. The specific lesions of lymphohistiocytic villitis or asymptomatic RPH do not predict significant pediatric disease by 7 years of age. At least for these 2 lesions, the placenta does not have diagnostic value to the infant. PMID:24450427

Bendon, Robert; Coventry, Susan; Bendon, Jean; Nordmann, Amelia; Schikler, Kenneth

2014-01-01

147

A follow-up study of vasectomy clients in East Pakistan.  

PubMed

135 married vasectomy adopters at least 3 months postoperative in 3 districts in East Pakistan were interviewed in the third quarter of 1968. About 3/5 of the men reported no complications. Among those reporting complications about 3/4 suffered from simple pain, about 1/2 from swelling, and 2/5 from physical weakness. 9 out of 10 men reported receiving postoperative instructions from their physicians; 99% of these men reported close following of the instructions. Fewer of those who received and followed advice reported postoperative complications than those who received no advice (39.7% vs. 47.1%, n=133). Of the 135 men in the study 38% reported changes in marital life: decreased sexual desire (29%), increased sexual desire (9%), and physical weakening (2%). 3 wives were found to be pregnant after the operation, but whether the operations were failures is uncertain. According to the men 69% of the wives were satisfied with the operation, 14% were dissatisfied, 8% were unaware of the operation, and 5% had feelings unknown to the husbands. Among husbands whose wives were happy and unhappy with the operation 98% and 74%, respectively, were themselves happy with the operation (p less than .005). 54% of the men told others about their operations; almost all of these recommended the operation. The physician should given postoperative advice. Weekly follow-up of patients should occur. PMID:12304786

Quddus, A H; Ratcliffe, J W; Croley, H T

1969-01-01

148

Impulsive and compulsive behaviors in Parkinson's disease: a one-year follow-up study.  

PubMed

Impulsive and compulsive behaviors (ICBs) have been reported to occur frequently in Parkinson's disease (PD) and include impulse control disorders (ICDs), punding and dopamine dysregulation syndrome (SSD). We report on the outcomes of 25 PD patients who developed ICBs. Information was collected on changes in parkinsonian and psychiatric medication follow-up (median=12.1 months). At time 1, only 18 patients (72%) were taking dopamine agonists (DA). At time 2, fifteen patients (83.33%) either discontinued or decreased their DA treatment. Of these patients, thirteen (86.67%) reported experiencing full or partial remission of their ICBs symptoms. When analyzing separately the 11 patients with punding, these symptoms remained unchanged in 9 patients (81.82%) independently of changes in dopaminergic drugs. In conclusion, the current study suggests that there are clear similarities, but also important differences, between punding and ICDs over time. Pathological gambling, binge or compulsive eating, pathological hypersexuality and compulsive shopping in PD were robustly associated with the use of DA but the relationship between dopaminergic medications and punding is less clear. It is important to determine if other treatment strategies may be effective for punding in PD. PMID:21683375

Ávila, Asunción; Cardona, Xavier; Martín-Baranera, Montse; Bello, Juan; Sastre, Francesc

2011-11-15

149

Long-term follow-up study of browlift for treatment of facial paralysis.  

PubMed

Browlift for patients with irreversible paralysis of the frontalis muscle was evaluated in a review of 40 patients who had undergone follow-up studies for durations of more than 3 years. The procedure consists of a lazy S-shaped excision above the upper border of the eyebrow and upward fixation of the lower skin margin. The results were as follows: (1) The percentage of patients for whom symmetrical positioning of the eyebrow was achieved was 65%. (2) The greater the preoperative severity of ptosis, the more often did recurrence occur. (3) Recurrence progressed rapidly during the first postoperative year, but thereafter recurrence was seen only in those patients in whom the affected eyebrow was still in a position higher than its counterpart. (4) No relationship could be seen between age at the time of surgery and postoperative position of eyebrow. (5) Improvement in contraction of the visual field was seen in 85% of patients postoperatively, and complaints were eliminated in 50%. (6) Careful preservation of the sensory nerve is required. (7) The postoperative scar was acceptable. This procedure is a simple and effective method of correction of paralytic ptosis. Although a degree of skill is required to obtain satisfactory results and a surgical scar remains at the upper border of the eyebrow, the advantages of the procedure surpass its disadvantages. It is believed that this method should be used more often in the treatment of facial paralysis. PMID:8192367

Ueda, K; Harii, K; Yamada, A

1994-02-01

150

Relationships between Reading, Phonological Skills and Language Development in Individuals With Down Syndrome: A Five Year Follow-Up Study.  

ERIC Educational Resources Information Center

Details language, memory, and reading information gathered for a five year follow up study of 30 children and adolescents with Down syndrome. Concludes that early learning skills may be significant predictors of mean length of utterance five years later. (PM)

Laws, Glynis; Gunn, Deborah

2002-01-01

151

Health Literacy as a Predictor of Follow-Up After an Abnormal Pap Smear: A Prospective Study  

PubMed Central

BACKGROUND Low literacy influences cervical cancer screening knowledge, and is a possible contributor to racial disparities in cervical cancer. OBJECTIVE To examine the hypothesis that literacy predicts patient adherence to follow-up recommendations after an abnormal Pap smear. DESIGN A prospective, continuity clinic-based study. PARTICIPANTS From a sample of 538 women undergoing literacy testing at the time of Pap smear screening, we studied 68 women with abnormal Pap smear diagnoses. MEASUREMENTS Literacy was assessed using the Rapid Evaluation of Adult Literacy in Medicine (REALM). We also measured other proxies for literacy, including educational attainment and physician estimates of patients' literacy level. Outcome measures included on-time and 1-year follow-up and duration of time to follow-up after an abnormal Pap smear. RESULTS Only one-third of the cohort adhered to follow-up recommendations. At 1 year, 25% of the women had not returned at all. Patients with inadequate literacy (as assessed by the REALM) were less likely to follow up within 1 year, although this result was not statistically significant (adjusted odds ratio [OR]=3.8, 95% confidence interval [CI]: 0.8 to 17.4). Patients subjectively assessed by their physician to have low literacy skills were significantly less likely to follow up within 1 year (adjusted OR=14, 95% CI: 3 to 65). Less than high school education (hazard ratio (HR)= 2.3; 95% CI: 1.2, 4.6) and low physician-estimated literacy level (HR=3.4, 95% CI: 1.4, 8.2), but not objective literacy level, were significant predictors of duration of time to follow-up, adjusting for recommended days to follow-up and other factors. CONCLUSIONS Among women with an abnormal Pap smear, those perceived by their physician to have low literacy were significantly more likely to fail to present for follow-up. PMID:16881942

Lindau, Stacy Tessler; Basu, Anirban; Leitsch, Sara A

2006-01-01

152

Prognosis of Fatigue and Functioning in Primary Care: A 1-Year Follow-up Study  

PubMed Central

PURPOSE Although fatigue is a common presenting symptom in primary care and its course and outcomes often remain unclear, cohort studies among patients seeking care for fatigue are scarce. We therefore aimed to investigate patterns in the course of fatigue and relevant secondary outcomes in a large cohort of patients who sought care for a main symptom of fatigue. METHODS We performed an observational cohort study in 147 primary care practices. Patients consulting their general practitioner for a new episode of fatigue were sent questionnaires at 1, 4, 8, and 12 months after baseline. We collected measures of fatigue, perceived health and functioning, absenteeism, psychological symptoms, and sleep using the Checklist Individual Strength, the 36-Item Short Form Health Survey, the Four-Dimensional Symptoms Questionnaire, and the Pittsburgh Sleep Questionnaire Inventory. Patients were classified into 4 subgroups based on fatigue severity scores over time. We assessed patterns in the course of all outcomes in these subgroups and in the total population, and tested changes over time and differences between subgroups. RESULTS A total of 642 patients were enrolled in the study. Response rates during follow-up ranged between 82% and 88%. For 75% of the patients, 4 distinct groups could be discerned: 26% of patients had continuously high scores for fatigue, 17% had a fast recovery, 25% had a slow recovery, and 32% initially improved but then had a recurrence of fatigue. Patterns for the secondary outcomes of symptoms and functioning were all similar to the pattern for fatigue within each of the subgroups. CONCLUSIONS The findings of this study suggest a longitudinal relationship between the severity of fatigue, impaired functioning, psychological symptoms, and poor sleep. Physicians should be aware that a substantial proportion of patients seeking care for fatigue have these additional health and psychosocial problems. PMID:19001304

Nijrolder, Iris; van der Windt, Daniëlle A.W.M.; van der Horst, Henriëtte E.

2008-01-01

153

Mechanical Engineering Curricula: A Follow-up Study for the Future Effects of ABET EC2000  

NSDL National Science Digital Library

The Accreditation Board for Engineering and Technology (ABET) is recognized by the U.S. Department of Education as the sole agency responsible for accreditation of educational programs leading to degrees in engineering, engineering technology, and related engineering areas. In the late 1990s, engineering programs began transitioning to a new Engineering Criteria 2000 (EC2000). By 2001, all engineering programs were required to be accredited under the new criteria. The philosophy of Engineering Criteria 2000 is to allow institutions and programs to define their mission and objectives to meet the needs of their constituents and enable program differentiation. Emphasis is placed on continuous improvement of programs based on the input of constituents and a process that links outcomes and assessment to program objectives. This current paper is a follow-up study to a preliminary study conducted by the author in 2000 that looked at the initial effects of ABET EC2000. The earlier study examined selected mechanical engineering programs to discern the impact of EC2000 on curriculum development during the initial implementation phase of the new criteria. Data on the layout and composition of mechanical engineering curricula for nine schools in the United States with Ph.D. programs and nine schools without Ph.D. programs was presented and is updated in this current work. Current results are also compared to a study by Robert E. Mates from the State University of New York at Buffalo entitled a Survey of Undergraduate ME Programs, conducted in 1987. The conclusions identify changes that have occurred in mechanical engineering curricula as the EC2000 assessment process has matured.

Whiteman, Wayne

154

Long term functioning in early onset psychosis: Two years prospective follow-up study  

PubMed Central

Background There were few studies on the outcome of schizophrenia in developing countries. Whether the outcome is similar to or different from developed world is still a point for research. The main aim of the current study was to know if patients with early onset non affective psychosis can behave and function properly after few years from start of the illness or not. Other aims included investigation of possible predictors and associated factors with remission and outcome. Method The study prospectively investigated a group of 56 patients with onset of psychosis during childhood or adolescence. Diagnosis made according to DSM-IV criteria and included; schizophrenia, psychotic disorder not otherwise specified and acute psychosis. Severity of psychosis was measured by PANSS. Measures of the outcome included; remission criteria of Andreasen et al 2005, the children's global assessment scale and educational level. Results Analysis of data was done for only 37 patients. Thirty patients diagnosed as schizophrenia and 7 with Psychotic disorder not otherwise specified. Mean duration of follow up was 38.4 +/- 16.9 months. At the end of the study, 6 patients (16.2%) had one episode, 23(62.1%) had multiple episodes and 8 (21.6%) continuous course. Nineteen patients (51.4%) achieved full remission, and only 11(29.7%) achieved their average educational level for their age. Twenty seven percent of the sample had good outcome and 24.3% had poor outcome. Factors associated with non remission and poor outcome included gradual onset, low IQ, poor premorbid adjustment, negative symptoms at onset of the illness and poor adherence to drugs. Moreover, there was tendency of negative symptoms at illness start to predict poor outcome. Conclusion Some patients with early onset non affective psychosis can behave and function properly after few years from the start of the illness. Although remission is a difficult target in childhood psychosis, it is still achievable. PMID:21801438

2011-01-01

155

Six Year Follow-Up Study of 1976-1978 Alumni and Stopouts. Research Report Series Volume XIV, No. 2.  

ERIC Educational Resources Information Center

In summer 1984, a follow-up study was conducted in Illinois at William Rainey Harper College (WRHC) of the stopouts and transfer and career program alumni who left WRHC between 1976 and 1978. The study sought to assess the long-term impact of WRHC on its students. A mailed survey and follow-up telephone calls to 1,294 former students yielded a 50%…

Lucas, John A.

156

Inadequate Follow-up of Abnormal Screening Mammograms: Findings From the Race Differences in Screening Mammography Process Study (United States)  

Microsoft Academic Search

Objective: Despite relatively high mammography screening rates, there are reports of inadequate follow-up of abnormal results. Our objective was to identify factors associated with inadequate follow-up, and specifically, to determine if this outcome differed by race\\/ethnicity. Methods: We studied 176 subjects with abnormal or inconclusive mammograms identified from a prospective cohort study of African-American (n = 635) and White (n

Beth A. Jones; Amy Dailey; Lisa Calvocoressi; Kam Reams; Stanislav V. Kasl; Carol Lee; Helen Hsu

2005-01-01

157

Usefulness of follow-up electrophysiologic study and event monitoring after successful radiofrequency catheter ablation of supraventricular tachycardia  

Microsoft Academic Search

We assessed the usefulness of routine follow-up electrophysiologic studies after successful catheter ablation for supraventricular tachycardia and the role of event monitoring as an alternative modality in 310 patients at 11 centers using an investigational catheter ablation system with closed-loop temperature control. A routine follow-up electrophysiologic study between 1 and 3 months after ablation was required as part of the

Alan B. Wagshal; Luis A. Pires; Patrick G. Yong; Suzan A. Moser; Frank Mazzola; Robert S. Mittleman; Shoei K. Stephen Huang

1995-01-01

158

Fatal Stroke after the Death of a Sibling: A Nationwide Follow-Up Study from Sweden  

PubMed Central

Background Although less studied than other types of familial losses, the loss of a sibling could be a potential trigger of stroke as it represents a stressful life event. We studied the association between loss of a sibling and fatal stroke up to 18 years since bereavement. Methodology/Principal Findings We conducted a follow-up study between 1981 and 2002, based on register data covering the total population of Swedes aged 40–69 years (n?=?1,617,010). An increased risk of fatal stroke (1.31 CI: 1.05, 1.62) was found among women who had experienced the loss of a sibling. No increase in the overall mortality risk was found in men (1.11 CI: 0.92, 1.33). An elevated risk in the short term (during the second and third half-year after the death) was found among both men and women, whereas longer-term elevation in risk was found primarily for women. Both external (1.47 CI: 1.00, 2.17) and not external (1.26 CI: 1.00, 1.60) causes of sibling death showed associations among women. In men, an association was found only if the sibling also died from stroke (1.78 CI: 1.00, 3.17). However, among women, we found an increased risk of stroke mortality if the sibling died from causes other than stroke (1.30 CI: 1.04, 1.62). Conclusions/Significance The findings suggest an increased risk of dying from stroke mortality after the death of a sibling, and that bereavement affects particularly women. It is important for health care workers to follow bereaved siblings and recognize potential changes of stress-levels and health related behaviours that could lead to risk of stroke. PMID:23451131

Rostila, Mikael; Saarela, Jan; Kawachi, Ichiro

2013-01-01

159

Work, Diabetes and Obesity: A Seven Year Follow-Up Study among Danish Health Care Workers  

PubMed Central

Objectives The rise in prevalence of diabetes is alarming and research ascribes most of the increase to lifestyle. However, little knowledge exists about the influence of occupational factors on the risk for developing diabetes. This study estimates the importance of work and lifestyle as risk factors for developing diabetes mellitus among healthcare workers and explores the association of work factors and obesity, which is a risk factor for diabetes. Methods Questionnaire-based prospective cohort study among 7,305 health care workers followed for seven years in the Danish National Diabetes Register. We used bivariate comparisons to give an unadjusted estimate of associations, followed by adjusted survival analysis and logistic regression models to estimate the influences of potential risk factors related to job, health and lifestyle on diabetes and obesity. Results During seven years of follow up, 3.5% of participants developed diabetes, associated with obesity (HR ?=? 6.53; 95% CI 4.68–9.10), overweight (HR ?=? 2.89; CI 2.11–3.96) age 50–69 y (HR ?=? 2.27; 95% CI 1.57–3.43) and high quality of leadership (HR ?=? 1.60; CI 1.19–2.16). Obesity at baseline was most common among the youngest employees, and was mainly associated with developing diabetes (OR ?=? 3.84; CI 2.85–5.17), impaired physical capacity and physical inactivity. In the occupational setting, obesity was associated with shift work, severe musculoskeletal pain, low influence, but also by good management, fewer role conflicts and a positive work-life balance. Looking only at non-smokers, removed the influence of age and pain. However, non-smokers also had higher depression scores and more role conflicts. Conclusions Confirming obesity as the strongest risk factor for developing diabetes, the present study identified few occupational risk factors. However, obesity, the key risk factor for diabetes, had a more variable relation with work than did diabetes. PMID:25068830

Poulsen, Kjeld; Cleal, Bryan; Clausen, Thomas; Andersen, Lars L.

2014-01-01

160

Disease activity in idiopathic intracranial hypertension: a 3-month follow-up study.  

PubMed

Idiopathic intracranial hypertension (IIH) is a disorder of raised intracranial pressure (ICP) in the absence of identifiable pathology. The purpose of this study was to evaluate the clinical presentation and monitor a 3-month course using frequent optical coherence tomography (OCT) evaluations, visual field testings and lumbar opening pressure measurements. A longitudinal study of 17 patients with newly diagnosed IIH and 20 healthy overweight controls were included in the study. Peripapillary retinal nerve fiber layer thickness (RNFLT) and retinal thickness (RT) measurements (Stratus OCT-3, fast RNFL 3.4 protocol), and Humphrey visual field testing were evaluated at regular intervals. Repeat lumbar puncture was performed at final visit (n = 13). The diagnostic delay was 3 months and initial symptoms were headache (94%), visual blurring (82%) and pulsatile tinnitus (65%). Complete clinical remission was achieved in 65%, partial in 29% and unchanged symptoms in 6%. Total average RNFLT and RT decreased significantly during the follow-up period (p < 0.0001 and p < 0.0001, respectively). Changes in RNFLT and RT correlated with improvements in visual field mean deviation (MD) (RNFLT: p = 0.006; RT: p = 0.03) and pattern standard deviation (PSD) (RNFLT: p = 0.002; RT: p = 0.003). In patients with weight-loss >3.5% of BMI, ICP decreased significantly (p = 0.0003). In patients with weight-loss <3.5% of BMI, changes in ICP were insignificant (p = 0.6). OCT combined with visual field testing may be a valuable objective tool to monitor IIH patients and the short term IIH outcome is positive. Weight-loss is the main predictor of a favorable outcome with respect to CSF pressure. PMID:20853113

Skau, Maren; Sander, Birgit; Milea, Dan; Jensen, Rigmor

2011-02-01

161

The clinical impact of a cardiologic follow-up in breast cancer survivors: an observational study.  

PubMed

Anthracycline-containing chemotherapy (A-CHT) can induce late cardiotoxicity adding a considerable burden to cardiovascular risk. Irradiation of left breast cancer has also been associated to an increased risk of cardiovascular disease. The aim of this observational study is to prove the usefulness of an accurate cardiovascular evaluation in left breast cancer survivors treated with radiotherapy (RT) and A-CHT. Patients with left breast cancer, on follow-up after treatment with A-CHT plus RT in an adjuvant setting, were eligible for this observational study. Patients underwent cardiovascular assessment with myocardial perfusion imaging. Thirty patients were enrolled in the study: mean age at diagnosis 55.8 years; stage: I/III; Er and/or pgR status: positive in 24/30 pts; 3 patients in pre-menopausal status. Twenty-two patients (73.3 percent) had normal perfusion imaging, 1 patient (3.3 percent) had a fixed myocardial perfusion defect, 7 patients (23.3 percent) had reversible myocardial perfusion defects; 1 patient (3 percent) with normal perfusion scan showed depressed rest and stress LVEF. Only 1 patient had a large defect and underwent coronary angiography and percutaneous coronary intervention. Five patients with small defect showed normal coronary arteries at Multislice Computed Tomography. Cardiovascular followup may reveal signs of A-CHT or RT-induced cardiotoxicity. A stress test combined with MPI- and GATED-derived data of ventricular systolic performance after stress can give information on the coronary reserve and the contractile reserve and allow early appropriate treatment. PMID:21244771

Gallucci, G; Coccaro, M; Storto, G; Lapadula, L; Tartarone, A; Nappi, A; Cammarota, A; Buonerba, C; Di Lorenzo, G; Fusco, V; Aieta, M

2010-01-01

162

A Survey of Instruments and Practices Associated with Teacher Education Follow-Up Studies  

ERIC Educational Resources Information Center

Teacher education programs that are NCATE accredited are required to have an assessment system that includes follow-up on their graduates. This assessment system is guided by NCATE Standard 2 which judges how each unit uses external information from graduates and employers to refine their teacher education program. These programs use the collected…

McCoy, Christine Ann Baker

2010-01-01

163

New Neuromuscular Symptoms in Patients with Old Poliomyelitis: A Three-Year Follow-Up Study  

Microsoft Academic Search

Fourteen survivors of paralytic poliomyelitis experienced new symptoms after years of stability. Seven patients had lost functional capacity, with joint pain, instability and recurrent falls, but were again stable and remained essentially unchanged during a 3-year follow-up period. Seven others had late postpoliomyelitis muscular atrophy (PPMA) with new weakness, wasting, fasciculations and myalgia in muscles originally spared or seemingly recovered.

Marinos C. Dalakas

1986-01-01

164

Follow-Up Study of Journalism Students--1985-1990. Volume XX, No. 8.  

ERIC Educational Resources Information Center

As part of the overall evaluation of its journalism program, William Rainey Harper College (WRHC), in Palatine, Illinois, conducted a follow-up survey of students who had completed three or more journalism courses between 1985 and 1990 to determine current activities and perceptions of the program. Questionnaires were mailed to all 80…

Havlic, S.; And Others

165

Follow up study of moderate alcohol intake and mortality among middle aged men in Shanghai, China.  

PubMed Central

OBJECTIVE: To assess the risk of death associated with various patterns of alcohol intake. DESIGN: Prospective study of mortality in relation to alcohol consumption at recruitment, with active annual follow up. SETTING: Four small, geographically defined communities in Shanghai, China. SUBJECTS: 18,244 men aged 45-64 years enrolled in a prospective study of diet and cancer during January 1986 to September 1989. MAIN OUTCOME MEASURE: All cause mortality. RESULTS: By 28 February 1995, 1198 deaths (including 498 from cancer, 269 from stroke, and 104 from ischaemic heart disease) had been identified. Compared with lifelong non-drinkers, those who consumed 1-14 drinks a week had a 19% reduction in overall mortality (relative risk 0.81; 95% confidence interval 0.70 to 0.94) after age, level of education, and cigarette smoking were adjusted for. This protective effect was not restricted to any specific type of alcoholic drink. Although light to moderate drinking (28 or fewer drinks per week) was associated with a 36% reduction in death from ischaemic heart disease (0.64; 0.41 to 0.998), it had no effect on death from stroke, which is the leading cause of death in this population. As expected, heavy drinking (29 or more drinks per week) was significantly associated with increased risks of death from cancer of the upper aerodigestive tract, hepatic cirrhosis, and stroke. CONCLUSIONS: Regular consumption of small amounts of alcohol is associated with lower overall mortality including death from ischaemic heart disease in middle aged Chinese men. The type of alcoholic drink does not affect this association. PMID:9001474

Yuan, J. M.; Ross, R. K.; Gao, Y. T.; Henderson, B. E.; Yu, M. C.

1997-01-01

166

Ergonomic stressors and upper extremity musculoskeletal disorders in automobile manufacturing: a one year follow up study  

PubMed Central

Aims: To estimate the one year cumulative incidence and persistence of upper extremity (UE) soft tissue disorders, in a fixed cohort of automotive manufacturing workers, and to quantify their associations with ergonomic exposures. Methods: At baseline and at follow up, cases of UE musculoskeletal disorders were determined by interviewer administered questionnaire and standardised physical examination of the upper extremities. The interview obtained new data on psychosocial strain and updated the medical and work histories. An index of exposure to ergonomic stressors, obtained at baseline interview, was the primary independent variable. Cumulative incidence and persistence of UE disorders (defined both by symptoms and by physical examination plus symptoms) were analysed in relation to baseline ergonomic exposures, adjusting for other covariates. The incidence of new disorders was modelled using multivariate proportional hazards regression among workers who were not cases in the first year and the prevalence on both occasions was modelled by repeated measures analysis. Results: A total of 820 workers (69% of eligible cohort members) was examined. Follow up varied slightly by department group but not by baseline exposure level or other characteristics. Among the non-cases at baseline, the cumulative incidence of UE disorders was 14% by symptoms and 12% by symptoms plus examination findings. These rates increased with index of physical exposures primarily among subjects who had the same jobs at follow up as at baseline. Increased exposure during follow up increased risk of incidence. The persistence of UE disorders from baseline to follow up examination was nearly 60% and somewhat associated with baseline exposure score. Conclusions: These longitudinal results confirm the previous cross sectional associations of UE musculoskeletal disorders with exposure to combined ergonomic stressors. The exposure-response relation was similar for incident cases defined by symptoms alone and those confirmed by physical examination. PMID:15258272

Punnett, L; Gold, J; Katz, J; Gore, R; Wegman, D

2004-01-01

167

Routine vaccinations and child survival: follow up study in Guinea-Bissau, West Africa  

PubMed Central

Objective To examine the association between routine childhood vaccinations and survival among infants in Guinea-Bissau. Design Follow up study. Participants 15?351 women and their children born during 1990 and 1996. Setting Rural Guinea-Bissau. Main outcome measures Infant mortality over six months (between age 0-6 months and 7-13 months for BCG, diphtheria, tetanus, and pertussis, and polio vaccines and between 7-13 months and 14-20 months for measles vaccine). Results Mortality was lower in the group vaccinated with any vaccine compared with those not vaccinated, the mortality ratio being 0.74 (95% confidence interval 0.53 to 1.03). After cluster, age, and other vaccines were adjusted for, BCG was associated with significantly lower mortality (0.55 (0.36 to 0.85)). However, recipients of one dose of diphtheria, tetanus, and pertussis or polio vaccines had higher mortality than children who had received none of these vaccines (1.84 (1.10 to 3.10) for diphtheria, tetanus, and pertussis). Recipients of measles vaccine had a mortality ratio of 0.48 (0.27 to 0.87). When deaths from measles were excluded from the analysis the mortality ratio was 0.51 (0.28 to 0.95). Estimates were unchanged by controls for background factors. Conclusions These trends are unlikely to be explained exclusively by selection biases since different vaccines were associated with opposite tendencies. Measles and BCG vaccines may have beneficial effects in addition to protection against measles and tuberculosis. PMID:11110734

Kristensen, Ines; Aaby, Peter; Jensen, Henrik

2000-01-01

168

A follow-up study of early interceptive treatment of primary anterior crossbites.  

PubMed

The purpose of this study was to investigate the outcome of early interceptive treatment of primary anterior crossbites with posterior occlusal acrylic resin blocks in combination with a 2 × 4 appliance, and to examine the differences in craniofacial morphology between the stable and relapse groups. Lateral cephalograms of 46 subjects (17 males and 29 females; average mean age 4 years 2 months ± 5 months) with a primary anterior crossbite were obtained before (T0) and immediately after (T1) treatment and at a 6 year follow-up (T2). The patients were assigned to either a stable (n = 35; 13 males and 22 females) or a relapse (n = 11; 4 males and 7 females) group according to the amount of overjet when the permanent incisors had erupted. The differences in craniofacial morphology between the groups were compared using a two-tailed t-test. The results revealed that the relapse subjects had a more forward position of the mandible relative to the cranial base and maxilla, a longer mandible and an increased gonial angle at T0. At T1, both groups had a positive overjet, but the treatment changes were different. Between T1 and T2, the maxillary length (A'-Ptm') increased less in the relapse group, the angle between the posterior border of the mandibular ramus and SN plane (Ram-SN) decreased and gonial angle increased and vice versa in the stable group. When posterior bite raising and 2 × 4 appliance therapy are used to correct primary anterior crossbites, all patients showed an immediate positive treatment response, whereas approximately one-quarter of subjects relapsed into a reverse overjet when the permanent incisors had erupted, mainly because of a more severe Class III craniofacial morphology at T1 and unfavourable growth during T1-T2. PMID:21239395

Ge, Yuanshu; Liu, Jin; Guo, Xin; Han, Jianli

2011-10-01

169

Prospective follow-up study lasting 2 years in patients with panic disorder with and without depressive disorders  

Microsoft Academic Search

A group of 52 patients presenting at an outpatient unit for anxiety disorders were included consecutively in a prospective 2-year follow-up study. Patients were administered to a structured interview for DSM-III-R diagnoses, a follow-up interview (LIFE), and various other ratings. Sociodemographic and illness-history characteristics, levels of anxiety and depressive symptoms, as well as psychosocial impairment, were evaluated at baseline and

Gabriele Scheibe; Margot Albus

1994-01-01

170

Recommendations for the Follow-Up of Study Participants with Breakthrough HIV Infections during HIV/AIDS Biomedical Prevention Studies  

PubMed Central

Objective To facilitate collection of cumulative data on longitudinal HIV disease outcomes during HIV prevention studies by developing recommendations for follow-up of the relatively few study participants with breakthrough infections. Design We formed a working group to compare and contrast the various approaches taken in recent HIV prevention trials, to summarize the advantages and disadvantages associated with each, and to explore the feasibility of developing protocols for the long-term follow-up of seroconverters. Methods We reviewed study designs, objectives, and assessments in 15 interventional studies that followed HIV seroconverters. Protocol team members joined discussions of the various approaches and developed recommendations. Results Most HIV prevention clinical trials share a core set of objectives, including the description/comparison of virological, immunological and clinical course of HIV, and sometimes a comparison of pre-and post-seroconversion behavior. Long-term follow-up of seroconverters can be conducted in separate studies if the transition from parent protocol is effectively managed. Conclusion We recommend the development of harmonized seroconverter protocols. Although specific research questions in the post-seroconversion period may differ depending on prevention modality, harmonizing key evaluations would create an opportunity to ask overarching questions that inform the prevention field with respect to design and implementation of future combination prevention studies. Follow-up immediately post-seroconversion should be conducted in the parent protocol before rollover into a follow-up protocol. Development of specimen repositories with ample volumes for future assays, standardized definitions of infection, diagnosis and seroconversion dates, and harmonization of study objectives and sample collections at key time points are important. PMID:23262497

Etter, Paige; Landovitz, Raphael; Sibeko, Sengeziwe; Sobieszczyk, Magdalena E.; Riddler, Sharon A.; Karg, Carissa; Tsibris, Athe; Schouten, Jeffrey

2014-01-01

171

Analyzes of genome-wide association follow-up study for calving traits in dairy cattle  

PubMed Central

Background There is often a pronounced disagreement between results obtained from different genome-wide association studies in cattle. There are multiple reasons for this disagreement. Particularly the presence of false positives leads to a need to validate detected QTL before they are optimally incorporated or weighted in selection decisions or further studied for causal gene. In dairy cattle progeny testing scheme new data is routinely accumulated which can be used to validate previously discovered associations. However, the data is not an independent sample and the sample size may not be sufficient to have enough power to validate previous discoveries. Here we compared two strategies to validate previously detected QTL when new data is added from the same study population. We compare analyzing a combined dataset (COMB) including all data presently available to only analyzing a validation dataset (VAL) i.e. a new dataset not previously analyzed as an independent replication. Secondly, we confirm SNP detected in the Reference population (REF) (i.e. previously analyzed dataset consists of older bulls) in the VAL dataset. Results Clearly the results from the combined (COMB) dataset which had nearly twice the sample size of other two subsets allowed the detection of far more significant associations than the two smaller subsets. The number of significant SNPs in REF (older bulls) was about four times higher compare to VAL (younger bulls) though both had similar sample sizes, 2,219 and 2,039 respectively. A total of 424 SNP-trait combinations on 22 chromosomes showed genome-wide significant association involving 284 unique SNPs in the COMB dataset. In the REF data set 101 associations (73 unique SNPs) and in the VAL 24 associations (18 unique SNPs) were found genome-wide significant. Sixty-eight percent of the SNPs in the REF dataset could be confirmed in the VAL dataset. Out of 469 unique SNPs showing chromosome-wide significant association with calving traits in the REF dataset 321 could be confirmed in the VAL dataset at P?follow-up study for GWAS in cattle will depend on the aim of the study. If the aim is to discover novel QTL, analyses of the COMB dataset is recommended, while in case of identification of the causal mutation underlying a QTL, confirmation of the discovered SNPs are necessary to avoid following a false positive. PMID:22888914

2012-01-01

172

Estimating bias from loss to follow-up in a prospective cohort study of bicycle crash injuries  

PubMed Central

Background Loss to follow-up, if related to exposures, confounders and outcomes of interest, may bias association estimates. We estimated the magnitude and direction of such bias in a prospective cohort study of crash injury among cyclists. Methods The Taupo Bicycle Study involved 2590 adult cyclists recruited from New Zealand's largest cycling event in 2006 and followed over a median period of 4.6?years through linkage to four administrative databases. We resurveyed the participants in 2009 and excluded three participants who died prior to the resurvey. We compared baseline characteristics and crash outcomes of the baseline (2006) and follow-up (those who responded in 2009) cohorts by ratios of relative frequencies and estimated potential bias from loss to follow-up on seven exposure-outcome associations of interest by ratios of HRs. Results Of the 2587 cyclists in the baseline cohort, 1526 (60%) responded to the follow-up survey. The responders were older, more educated and more socioeconomically advantaged. They were more experienced cyclists who often rode in a bunch, off-road or in the dark, but were less likely to engage in other risky cycling behaviours. Additionally, they experienced bicycle crashes more frequently during follow-up. The selection bias ranged between ?10% and +9% for selected associations. Conclusions Loss to follow-up was differential by demographic, cycling and behavioural risk characteristics as well as crash outcomes, but did not substantially bias association estimates of primary research interest. PMID:24336816

Tin Tin, Sandar; Woodward, Alistair; Ameratunga, Shanthi

2014-01-01

173

Left-hemisphere missile injury. A clinical and anatomical case study, with 25-year follow up.  

PubMed

A case is reported of left-hemisphere missile injury sustained in 1944. A stable pattern of selective loss (dysphasia, dyslexia, dysgraphia, and verbal memory impairment) and intact abilities (perceptual and spatial skills and nonverbal memory) was followed up for 25 years. No progressive or generalized intellectual deterioration to suggest interaction between this brain injury and normal aging was observed. The clinical and neuropsychological sequelae are related to the detailed postmortem findings. PMID:3632396

Oppenheimer, D; Marshall, J C; Newcombe, F

1987-08-01

174

Beneficial effects of Helicobacter pylori eradication on migraine: a 12-month follow-up study  

Microsoft Academic Search

Helicobacter pylori (H. pylori) has been recently associated with some organic and functional vascular disorders. In particular, our group found a high\\u000a prevalence of H. pylori in patients affected by migraine and a significant improvement of migraine symptoms after eradication of the bacterium, during\\u000a a follow-up period of 6 months. However, seasonal variations may affect clinical manifestations of migraine, thus

Maurizio Gabrielli; Francesco Franceschi; Giuseppe Fiore; Marcello Candelli; Alessandro Armuzzi; Veronica Ojetti; Filippo Cremonini; Paolo Pola; Mario Giacovazzo; Antonio Gasbarrini

2001-01-01

175

Transdermal application of methimazole in hyperthyroid cats: a long-term follow-up study.  

PubMed

Transdermal methimazole is suggested as an alternative to oral therapy for hyperthyroid cats that are difficult to pill. However, no information on long-term management with this treatment is available. Our objective was therefore to retrospectively evaluate the efficacy and safety of long-term transdermal methimazole treatment in hyperthyroid cats. Sixty cats with newly diagnosed hyperthyroidism and available long-term follow-up information were included. Methimazole was formulated in a pluronic lecithin organogel-based vehicle and was applied to the pinna of the inner ear. Cats were re-evaluated at regular intervals. Median (range) follow-up was 22.6 months (3.6-88.4 months). Clinical improvement was observed in all cats and side effects were rare (mild transient gastrointestinal signs: n = 3; erythema of the pinna: n = 2, necessitating a switch to oral medication). Despite a significant decrease, with median T4 concentrations within the reference interval during the follow-up period, several cats repeatedly had T4 concentrations in the thyrotoxic and hypothyroid range. Maximal and minimal daily doses during the follow-up period were 15.0 and 1.0 mg, respectively; they were significantly higher than the starting dose after 24-36 months of therapy. Although the majority of owners were highly satisfied with the treatment, several admitted not treating their cat regularly. Transdermal methimazole is a safe option for the long-term management of feline hyperthyroidism. However, it seems difficult to keep the T4 concentrations constantly within the reference interval. Higher doses can be expected after prolonged treatment and, despite the convenience of transdermal application, owner compliance should be assessed regularly. PMID:24174499

Boretti, Felicitas S; Sieber-Ruckstuhl, Nadja S; Schäfer, Sandra; Gerber, Bernhard; Baumgartner, Claudia; Riond, Barbara; Hofmann-Lehmann, Regina; Reusch, Claudia E

2014-06-01

176

Crack Cocaine: A Five-Year Follow-Up Study of Treated Patients  

Microsoft Academic Search

Objectives: To follow-up a group of 131 crack cocaine users and examine drug use, treatment experience, employment status, involvement in crime and mortality at 2 and 5 years. Methods: Consecutive crack-dependent patients who were admitted to a detoxification unit in São Paulo between 1992 and 1994 were re-interviewed on two occasions: 1995–1996 and 1998–1999. Results: 5 years after treatment information

M. Ribeiro; J. Dunn; R. Sesso; M. S. Lima; R. Laranjeira

2007-01-01

177

The sexual struggles of 23 clergymen: a follow-up study.  

PubMed

Nineteen clergymen, 17 of whom were Catholic, were followed up 1 to 6 years after their initial evaluation in a program designed to assess the sexual offenses and rehabilitation potential of offending professionals. Methods used included a semistructured interview with a research psychiatrist and a repeat of the MCMI-III. At follow-up, the clergymen were relatively psychologically healthy. The vast majority of the men had returned to previous or higher levels of vocational functioning and felt that they had benefited from their initial evaluation and therapy. None of those who were initially suspected of sexual compulsivity met criteria for excessive sexual expression at follow-up, and none had re-offended. The typical clergyman, whether heterosexual or homosexual, was struggling with loneliness, masturbation conflicts, and the wish to be known beyond their role by others. The confrontative style of the evaluators in pursuing the veracity of the clergy's initial explanations of their behaviors and the use of penile plethysmography were the primary objections to the methods used. Brief psychotherapy seemed to be a cost-effective, well-received intervention for clergy struggling with their sexual conflicts. PMID:10407791

Fones, C S; Levine, S B; Althof, S E; Risen, C B

1999-01-01

178

Parathyroidectomy in chronic renal failure: a nine-year follow-up study.  

PubMed

Seventy-three patients with chronic renal failure who underwent parathyroidectomy between March 1978 and April 1987 were reviewed. Thirty-four patients had undergone sub-total parathyroidectomy, and 39 patients had undergone total parathyroidectomy with parathyroid autograft into the forearm. Eight patients showed persistent hyperparathyroidism requiring a second surgical procedure. In all other patients there was highly statistical improvement in parathyroid hormone, total calcium, ionized calcium, alkaline phosphatase and a significant reduction in calcium x phosphate product. Histological evidence of osteitis fibrosa was present in 21 of 22 patients before surgery. Postoperatively, four showed complete resolution and improvement. Three patients developed histological evidence of osteomalacia during the study period. Only four of the 39 patients who underwent total parathyroidectomy with autograft had true recurrent hyperparathyroidism and only two of the 34 patients who underwent sub-total parathyroidectomy had recurrent disease, indicating that there is little to choose between the two techniques in the control of secondary hyperparathyroidism and its subsequent recurrence. In one patient with recurrence of hyperparathyroidism from a forearm parathyroid graft the histological picture was different from that of normal hyperplastic parathyroid tissue. Although it is probable that abnormal parathyroid tissue had been implanted there was no evidence of invasive growth into the forearm muscle. The most striking feature of long term follow-up was the difference in calcium x phosphate product in patients in whom vascular calcification increased compared to those patients with no change or regression of calcification. Mean calcium phosphate product in those patients with progressive vascular calcification was 4.93 for small and medium size vessels and 5.38 for large vessels compared to 4.10 for small and medium vessels and 4.09 for large vessels. In the former case the serum phosphate was 2.00 and 2.17 as compared to 1.75 or 1.73, suggesting that the aim in patients with end stage renal failure maintained by dialysis should be to control the serum phosphate concentration to 1.8 mmol or less and the calcium x phosphate product to less than 4.2. PMID:2274659

Nichols, P; Owen, J P; Ellis, H A; Farndon, J R; Kelly, P J; Ward, M K

1990-11-01

179

Results of follow-up study in cardiac pacing at St. Raphael University Hosital in Leuven.  

PubMed

After this follow-up period some data seem important for the future: 1. Sudden failure never occurred for ventricular asynchronous units. Moreover battery survival time of fixed rate units is longer than that of ventricular-inhibited units. On the other hand, the use of fixed rate pacers avoids a number of demand function-related electrode difficulties. We must be aware of false signals generated by malfunctioning electrodes. 2. The reliability of a pacemaker clinic improves by replacing ventricular-inhibited units after 34 months. 3. Despite the additional work and cost we feel that photoanalysis is indispensable in today's pacemaker clinic. PMID:1087809

Ector, H; Emmerechts, C; De Schepper, S; De Geest, H

1976-01-01

180

Long-term follow-up study of gastroduodenal lesions after radioembolization of hepatic tumors  

PubMed Central

AIM: To evaluate the long-term natural history of the gastroduodenal lesions secondary to extrahepatic embolization with Ytrium 90 (90Y) spheres. METHODS: From September 2003 to January 2012, 379 procedures of liver radioembolization (RE) using resin microspheres loaded with 90Y were performed in our center. We have retrospectively compiled the data from 379 RE procedures performed in our center. We report a comprehensive clinical, analytical, endoscopic and histologic long-term follow-up of a series of patients who developed gastroduodenal lesions after the treatment. RESULTS: Six patients (1.5%) developed gastrointestinal symptoms and had gastrointestinal lesions as shown by upper endoscopy in the next 12 wk after RE. The mean time between RE and the appearance of symptoms was 5 wk. Only one patient required endoscopic and surgical treatment. The incidence of gastrointestinal ulcerations was 3.75% (3/80) when only planar images were used for the pre-treatment evaluation. It was reduced to 1% (3/299) when single-photon emission computed tomography (SPECT) images were also performed. The symptoms that lasted for a longer time were nausea and vomiting, until 25 mo after the treatment. CONCLUSION: All patients were free from severe symptoms at the end of follow-up. The routine use of SPECT has decreased the incidence of gastrointestinal lesions due to unintended deployment of 90Y particles. PMID:23704826

Rodríguez-Lago, Iago; Carretero, Cristina; Herráiz, Maite; Subtil, José C; Betés, Maite; Rodríguez-Fraile, Macarena; Sola, Jesús J; Bilbao, José I; Muñoz-Navas, Miguel; Sangro, Bruno

2013-01-01

181

Predictors of Retention in an Online Follow-up Study of Men Who Have Sex With Men  

PubMed Central

Background In the past 10 years, the Internet has emerged as a venue for men who have sex with men (MSM) to meet sex partners. Because online sex seeking has increased among MSM, Internet-based human immunodeficiency virus (HIV) prevention interventions are of interest. However, few online studies to date have demonstrated an ability to retain study participants, specifically MSM of color, in longitudinal online studies. Objective The current analysis examines data from a 3-month online prospective study of MSM to determine the association of race and incentive level with two retention outcomes: (1) agreeing to participate in a follow-up survey and providing an email address and (2) linking into the follow-up survey at the follow-up time point. Methods Internet-using MSM were recruited through banner advertisements on MySpace.com. White, black, and Hispanic participants from 18 to 35 years of age were randomized to an offer of enrollment in an online follow-up survey at four levels of incentive (US $0, US $5, US $10, and US $20). Multivariable logistic regression models were used to estimate the odds of the two outcome measures of interest controlling for additional independent factors of interest. Results Of eligible participants, 92% (2405/2607) agreed to participate in the follow-up survey and provided an email address. Hispanic men had decreased odds (adjusted odds ratio [OR] = 0.66, 95% confidence interval [CI] 0.47-0.92) of agreeing to participate in the follow-up survey compared with white men. Men reporting unprotected anal intercourse with a male sex partner in the past 12 months had increased odds of agreeing to participate in the follow-up survey (adjusted OR = 1.42, 95% CI 1.05-1.93). Of the participants who provided an email address, 22% (539/2405) linked into the follow-up survey at the 3-month follow-up time point. The odds of linking into the follow-up survey for black men were approximately half the odds for white men (adjusted OR = 0.47, 95% CI 0.35-0.63). Participants who were offered an incentive had increased odds of linking into the follow-up survey (adjusted OR = 1.29, 95% CI 1.02-1.62). Email addresses provided by participants that were used for online financial management and email accounts that were checked daily were associated with increased odds of linking into the follow-up survey (adjusted OR = 1.97, 95% CI 1.54-2.52; adjusted OR = 1.51, 95% CI 1.22-1.87, respectively). Conclusions This analysis identified factors that predicted retention in an online, prospective study of MSM. Hispanic and black study participants were less likely to be retained in the study compared with white study participants. Because these men bear the greatest burden of HIV incidence among MSM in the United States, it is critical that new research methods be developed to increase retention of these groups in online research studies. PMID:21745792

Khosropour, Christine M

2011-01-01

182

Stability and relapse after orthodontic treatment of deep bite cases-a long-term follow-up study.  

PubMed

The purpose of this long-term follow-up study was twofold-firstly, to assess prevalence of relapse after treatment of deep bite malocclusion and secondly, to identify risk factors that predispose patients with deep bite malocclusion to relapse. Sixty-one former patients with overbite more than 50% incisor overlap before treatment were successfully recalled. Clinical data, morphometrical measurements on plaster casts before treatment, after treatment and at long-term follow-up, as well as cephalometric measurements before and after treatment were collected. The median follow-up period was 11.9 years. Patients were treated by various treatment modalities, and the majority of patients received at least a lower fixed retainer and an upper removable bite plate during retention. Relapse was defined as increase in incisor overlap from below 50% after treatment to equal or more than 50% incisor overlap at long-term follow-up. Ten per cent of the patients showed relapse to equal or larger than 50% incisor overlap, and their amount of overbite increase was low. Among all cases with deep bite at follow-up, gingival contact and palatal impingement were more prevalent in partially corrected noncompliant cases than in relapse cases. In this sample, prevalence and amount of relapse were too low to identify risk factors of relapse. PMID:23197574

Danz, J C; Greuter, C; Sifakakis, I; Fayed, M; Pandis, N; Katsaros, C

2014-10-01

183

Meat consumption and meat avoidance among young people : An 11-year longitudinal study  

Microsoft Academic Search

This paper reports the findings of an 11-year longitudinal study of the food preferences of first-year social science undergraduates at a UK university. Argues that this predominantly young and female response group constitutes a “critical case” that can be used to assess broader trends in meat consumption and meat avoidance. Relatively high levels of meat avoidance (in terms of reduced

Alan Beardsworth; Alan Bryman

2004-01-01

184

SLUDGE BATCH 4 FOLLOW-UP QUALIFICATION STUDIES TO EVALUATE HYDROGEN GENERATION  

SciTech Connect

Follow-up testing was conducted to better understand the excessive hydrogen generation seen in the initial Sludge Batch 4 (SB4) qualification Sludge Receipt and Adjustment Tank/Slurry Mix Evaporator (SRAT/SME) simulation in the Savannah River National Laboratory (SRNL) Shielded Cells. This effort included both radioactive and simulant work. The initial SB4 qualification test produced 0.59 lbs/hr hydrogen in the SRAT, which was just below the DWPF SRAT limit of 0.65 lbs/hr, and the test produced over 0.5 lbs/hr hydrogen in the SME cycle on two separate occasions, which were over the DWPF SME limit of 0.223 lbs/hr.

Pareizs, J; David Koopman, D; Dan Lambert, D; Cj Bannochie, C

2007-08-23

185

Five-year follow-up study of the prevalence and progression of pulmonary hypertension in systemic lupus erythematosus  

Microsoft Academic Search

The purpose of this study was to determine the prevalence and progression of pulmonary hypertension over a 5-year follow-up period in 28 patients with systemic lupus erythematosus (SLE) who were originally enrolled in an echocardiographic study of pulmonary hypertension in 1985 and 1986. Twenty healthy volunteers without cardiac or pulmonary disease participated as normal controls. Each patient and control underwent

Timothy M. Winslow; Maxim A. Ossipov; Gary P. Fazio; Jay S. Simonson; Rita F. Redberg; Nelson B. Schiller

1995-01-01

186

Use of dietary supplements in Olympic athletes is decreasing: a follow-up study between 2002 and 2009  

Microsoft Academic Search

BACKGROUND: The aim of this study was to assess the frequency of use of dietary supplements (DS) among large sample of elite Finnish athletes and to describe possible changes in dietary supplement use between the years 2002 and 2009. METHODS: A prospective follow-up study was conducted on Olympic athletes. The first survey was conducted on Olympic athletes in 2002 (N

Anni Heikkinen; Antti Alaranta; Ilkka Helenius; Tommi Vasankari

2011-01-01

187

The School of Technical Careers Baccalaureate Program: A Follow-Up Study of Graduates of 1974 and 1975.  

ERIC Educational Resources Information Center

A follow-up study of the first two graduating classes (1974 and 1975) of the School of Technical Careers (STC) Baccalaureate Program was conducted. Questionnaires were sent to eighty-seven graduates (of ninety) who had United States addresses on file. Questions pertained to current labor market status, current occupation, first job after…

Walsh, E. Michael; Reynolds, R. John

188

Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients  

Microsoft Academic Search

BACKGROUND & AIMS: Few data are available concerning the long-term prognosis of chronic liver disease associated with hepatitis C virus infection. This study examined the morbidity and survival of patients with compensated cirrhosis type C.METHODS: A cohort of 384 European cirrhotic patients was enrolled at seven tertiary referral hospitals and followed up for a mean period of 5 years. Inclusion

G Fattovich; G Giustina; F Degos; F Tremolada; G Diodati; P Almasio; F Nevens; A Solinas; D Mura; JT Brouwer; H Thomas; C Njapoum; C Casarin; P Bonetti; P Fuschi; J Basho; A Tocco; A Bhalla; R Galassini; F Noventa; SW Schalm; G Realdi

1997-01-01

189

Occupational Physical Activity, Overweight, and Mortality: A Follow-Up Study of 47,405 Norwegian Women and Men  

ERIC Educational Resources Information Center

This population-based 24-year follow-up study evaluated the association of occupational physical activity (OPA) with overweight and mortality in 47,405 men and women, healthy at baseline, and reporting OPA as sedentary (reference), light, moderately heavy, or heavy. The adjusted odds ratio for overweight was slightly less than 1 for all categories…

Graff-Iversen, Sidsel; Selmer, Randi; Sorensen, Marit; Skurtveit, Svetlana

2007-01-01

190

Long-Term Follow-Up Study of Legal Tech Graduates, 1984-1988. Volume XVIII, No. 5.  

ERIC Educational Resources Information Center

In order to provide information for the 1989-90 program review at William Rainey Harper College (WRHC) and to fulfill American Bar Association accreditation guidelines, a long-term, follow-up study was conducted of all Legal Tech program alumni who graduated between 1984 and 1988. A telephone survey generated usable responses from 106 (73%) of the…

Lucas, John A.; Hildebrandt, Sharrie

191

Follow-Up Study of Former Computer Information Systems Students, 1986-1990. Volume XX, No. 6.  

ERIC Educational Resources Information Center

In fall 1991, a follow-up study was conducted of former Computer Information System (CIS) program students at William Rainey Harper College (WRHC), in Palatine, Illinois, in an effort to evaluate and provide future direction for the program. All students who had taken four or more CIS courses between summer 1986 and spring 1990, but were not…

Bender, Virginia; And Others

192

A Follow-Up Study of the Writing as Process Seminars in the Elementary School. Final Report.  

ERIC Educational Resources Information Center

In order to ascertain the impact of post-graduate course work on curricular practice, a follow-up study was undertaken of the classroom writing practices of participants in the 1987 Writing as Process seminars sponsored by William Paterson College, New Jersey. Seminars were offered in four elementary school districts, each one taught by a William…

Feeley, Joan T.

193

Follow-Up Study of Dietetic Tech Graduates 1986 and 1987 [and] 1983 and Prior. Volume XVII, Number 4.  

ERIC Educational Resources Information Center

In spring 1988, a study was conducted at William Rainey Harper College (WRHC), Illinois, to gather follow-up information about graduates of the college's Dietetic Technician program. Questionnaires were mailed to the 16 students who graduated from the program in 1986 and 1987 and to the 76 former students who graduated prior to 1984. Information…

Flaherty, Toni

194

Communication Development and Characteristics of Influencing Factors: A Follow-Up Study from 8 to 36 Months  

ERIC Educational Resources Information Center

In this follow-up study, we evaluated children's communication development at the ages of 8 ("n" ?= ?50), 18 ("n" ?=? 46), 24 ("n"? = ?44) and 36 months ("n"? = ?36) using the Finnish version of the "MacArthur Communicative Developmental Inventories" (MCDI). A sample of children ("n"? = ?14) received family-based intervention 10 times in five…

Haapsamo, Helena; Kuusikko-Gauffin, Sanna; Ebeling, Hanna; Larinen, Katja; Penninkilampi-Kerola, Varpu; Soini, Hannu; Moilanen, Irma

2013-01-01

195

Perceptions of Teachers of Students with Visual Impairments regarding Assistive Technology: A Follow-Up Study to a University Course  

ERIC Educational Resources Information Center

Introduction: The study presented here examined the learning outcomes of graduate students in visual impairment who were enrolled in an assistive technology course in three university programs. Methods: The students' perceptions of learning were evaluated using pre- and posttests administered during the course. A follow-up questionnaire was…

Kamei-Hannan, Cheryl; Howe, Jon; Herrera, Robyn Rene; Erin, Jane N.

2012-01-01

196

Third National Even Start Evaluation: Follow-Up Findings from the Experimental Design Study. NCEE 2005-3002  

ERIC Educational Resources Information Center

Citation: Ricciuti, A.E., R.G. St.Pierre, W. Lee, A. Parsad & T. Rimdzius. Third National Even Start Evaluation: Follow-Up Findings From the Experimental Design Study. U.S. Department of Education, Institute of Education Sciences, National Center for Education Evaluation and Regional Assistance. Washington, D.C., 2004. Background: The Even Start…

Ricciuti, Anne E., St.Pierre, Robert G.; Lee, Wang; Parsad, Amanda

2004-01-01

197

The Emerging Trend of EDP Auditing and the Implications for Collegiate Accounting Education: A 5-Year Follow-Up Study.  

ERIC Educational Resources Information Center

A five-year follow-up study compares the current business school curriculum content in electronic data processing and statistical sampling to the requirements of business. Differences still exist but there is evidence of progress by business schools in meeting the needs of business. (JOW)

Skudrna, Vincent J.; DiPillo, Pasquale J.

1988-01-01

198

Follow-Up Study of Former Harper College Sociology and/or Anthropology Graduates. Volume XXII, Number 13, February 1994.  

ERIC Educational Resources Information Center

A follow-up study was conducted at William Rainey Harper College (Illinois) to gather information from former sociology and/or anthropology students that would be useful in evaluating the sociology/anthropology department. All 696 students who had been enrolled in the last 5 years and had taken at least three courses in sociology and/or…

Lucas, J. A.; Meltesen, C.

199

Level of suicidal intent predicts overall mortality and suicide after attempted suicide: a 12-year follow-up study  

Microsoft Academic Search

BACKGROUND: The aim of this study was to comprehensively examine clinical risk factors, including suicide intent and hopelessness, for suicide and risk of death from all causes after attempted suicide over a 12-year follow-up period. METHODS: A systematic sample of 224 patients from consecutive cases of attempted suicide referred to health care in four Finnish cities between 1 January and

Kirsi Suominen; Erkki Isometsä; Aini Ostamo; Jouko Lönnqvist

2004-01-01

200

Beginning Postsecondary Students Longitudinal Study: First Follow-Up 1996-98 (BPS:96/98) Methodology Report. Technical Report.  

ERIC Educational Resources Information Center

This report describes the methods and procedures used for the full-scale data collection effort of the Beginning Postsecondary Students Longitudinal Study First Follow-Up 1996-98 (BPS:96/98). These students, who started their postsecondary education during the 1995-96 academic year, were first interviewed during 1996 as part of the National…

Wine, Jennifer S.; Whitmore, Roy W.; Heuer, Ruth E.; Biber, Melissa; Pratt, Daniel J.

201

Methods and Measures Used for Follow-up at 15 Years of the English and Romanian Adoptee (ERA) Study  

ERIC Educational Resources Information Center

This chapter covers the methods and measures used in the ERA study, with a special focus on age 15 outcomes. First, the authors outline the sample participation rate for the 15-year follow-up--the percentages in all cases referring to the numbers at the time of initial sample contact. They then describe the measures used in this monograph,…

Monographs of the Society for Research in Child Development, 2010

2010-01-01

202

Psychological Vulnerability in Children Next-Born after Stillbirth: A Case-Control Follow-Up Study  

ERIC Educational Resources Information Center

Background: Case studies and anecdotal accounts suggest that perinatal loss may impact upon other children in the family, including those born subsequent to loss. However, there is a dearth of systematically collected quantitative data on this potentially vulnerable group. Methods: Case-controlled follow-up of 52 mothers with history of stillbirth…

Turton, Penelope; Badenhorst, William; Pawlby, Susan; White, Sarah; Hughes, Patricia

2009-01-01

203

Long-Term Effectiveness of Behavioral versus Insight-Oriented Marital Therapy: A 4-Year Follow-Up Study.  

ERIC Educational Resources Information Center

Obtained 4-year follow-up data regarding marital status and marital accord for 59 couples receiving either behavioral (BMT) or insight-oriented (IOMT) marital therapy in a controlled outcome study. Found no significant group differences between the two treatment conditions at termination or six-month followup; but by four-year followup, a…

Snyder, Douglas K.; And Others

1991-01-01

204

Follow up Study of Children 5-8 Years Using Child Protection Programmes in Australia and New Zealand.  

ERIC Educational Resources Information Center

A follow-up study examined two programs intended to prevent child sexual abuse: (1) Protective Behaviors (Australia), which develops assertiveness skills to empower children; and (2) Keeping Ourselves Safe (New Zealand), which uses "What if..." problem-solving exercises. Revealed the importance of providing a school-based program that is…

Briggs, Freda; Hawkins, Russell M. F.

1994-01-01

205

Denham total knee arthroplasty: a 10-year follow-up study.  

PubMed

We reviewed 72 patients with 89 Denham total knee arthroplasties (Biomet, Warsaw, IN) (TKAs) 10 to 15 years after the operation. Of 8 TKAs that were considered as failures, 5 had been revised at the time of review for pain and aseptic loosening, and 3 others were considered to have failed because of breakage of the polyethylene tibial plateau, dislocation, and infection. Survival analysis suggested a 10-year survival rate of 92.7%. There were 36 patients with 45 TKAs alive at the time of follow-up. We reviewed 32 of the patients with 40 Denham TKAs that had not failed. Their average age was 81 years (range, 58-93 years). They were reviewed at an average of 11.8 years after TKA. Nine knees (6 patients) had some anterior knee pain from the unresurfaced patella. Restriction of function was mainly due to medical conditions and old age. Survival analysis performed with the living patients found the 10-year survival to be 91.1%. Long-term survival shows that the Denham knee prosthesis is effective despite its simplicity. PMID:12168168

Mangaleshkar, Singu R; Bajaj, Sunil K; Thomas, Andrew P

2002-08-01

206

Body Structures and Physical Complaints in Upper Limb Reduction Deficiency: A 24-Year Follow-Up Study  

PubMed Central

Objective To describe upper body structures associated with upper limb reduction deficiency and the development of these structures over time, to examine the presence of physical complaints in this population, and to compare body structures and complaints between groups based on prosthesis use. Design Prospective cohort study with a follow-up period of 24 years, with matched able-bodied controls. Subjects Twenty-eight patients with unilateral below-elbow reduction deficiency fitted with myoelectric prostheses, aged 8–18 years at inclusion. Method Measurements of upper arm, trunk and spine were performed and study-specific questionnaires were answered at baseline and follow-up; the Brief Pain Inventory and the Quick Disability of Arm, Shoulder, and Hand questionnaires were answered at follow-up. Results Both at baseline and follow-up, within-subjects differences in structures of the arm and trunk were shown in patients but not in controls. Spinal deviations, although small, were greater in patients compared to controls. Self-reported disability was higher in patients compared to controls. Differences in back pain and effect of prostheses use could not be shown. Conclusions Patients with unilateral below-elbow reduction deficiency have consistent differences in upper body structures. Deviations of the spine, probably of functional origin, do not progress to clinically relevant scoliosis. PMID:23226218

Postema, Sietke G.; van der Sluis, Corry K.; Waldenlöv, Kristina; Norling Hermansson, Liselotte M.

2012-01-01

207

Adherence to Antiretroviral Therapy in Jinja, Uganda: A Six-Year Follow-Up Study  

PubMed Central

Introduction We report on the adherence experience of a group of people living with HIV on ART over six years in Uganda. Methods Between 2005 and 2009, we followed up 41 participants who were also part of a clinical trial comparing home and facility based delivery of ART in Jinja, eastern Uganda. We conducted qualitative in-depth interviews at enrolment, 3, 6, 18 and 30 months to capture experiences with adherence over time. In 2011 we returned to these participants to find out how they were fairing with long term adherence. We managed to retrace 24 participants and interviewed them about their experience. We thematically analysed the data and compared findings over time. Results Initially there were few barriers to adherence and many followed the adherence guidance closely. By year six, relaxation of these rules was noticeable although self-reported adherence continued to be high. Alcohol consumption was more common than before. Some relatives of the participants who had died claimed that some deaths were a result of alcohol. While participants reported that ART had allowed them to reclaim independence and return to work the changes in work and social routines created new challenges for adherence. Side effects like lipodystrophy were not only causing some stigma but for some tested their faith in the drugs. Many participants reported resumption of sexual lives but apart from those who selected same status partners, disclosure to new partners was minimal. Conclusion Good adherence practice to ART wanes over the long-term, and people who may have disclosed at initiation find it difficult to do so to new partners once they are healthy. Further adherence interventions and support with disclosure over the course of therapy may need to be considered. (Words: 283) PMID:24147126

Mbonye, Martin; Seeley, Janet; Ssembajja, Fatuma; Birungi, Josephine; Jaffar, Shabbar

2013-01-01

208

EMCS (Energy Monitoring and Control Systems) Installation Follow-Up study. Volume I. Final report April 1983March 1984  

Microsoft Academic Search

This report provides the Task 3 deliverables for an EMCS Installation Follow-Up study. The objective of this study is to provide data on experience at existing EMCS installations for use in developing guidelines for better implementation of EMCS. Section 2.0 of this report provides a list of probable causes for EMCS success\\/failure identified in previous studies. Section 3.0 discusses whether

Bruning

1984-01-01

209

Remission of nephrotic syndrome in type 1 diabetes: Long-term follow-up of patients in the Captopril Study  

Microsoft Academic Search

In 1994, we reported a 3.4 ± 0.8 year follow-up of the eight patients who experienced remission of nephrotic syndrome during the Collaborative Study Group–sponsored, multicenter trial of captopril therapy in patients with type 1 diabetes with nephropathy (Captopril Study). Of the 409 patients randomized to treatment on the Captopril Study, 108 had nephrotic syndrome (24-hour proteinuria ? 3.5 g

William A. Wilmer; Lee A. Hebert; Edmund J. Lewis; Richard D. Rohde; Frederick Whittier; Daniel Cattran; Andrew S. Levey; Julia Breyer Lewis; Samuel Spitalewitz; Samuel Blumenthal; Raymond P. Bain

1999-01-01

210

A 4-year follow-up study of the effects of calcium supplementation on bone density in elderly postmenopausal women  

Microsoft Academic Search

To determine the long-term effect of calcium supplementation on bone density, 84 elderly women (54–74 years) more than 10 years past the menopause were studied for 4 years as part of a follow-up study of a randomized, double-masked, placebo-controlled trial. The placebo group who did not take calcium supplements at all during the 4-year study (control group,n=21) served as a

A. Devine; I. M. Dick; S. J. Heal; R. A. Criddle; R. L. Prince

1997-01-01

211

Oral health follow-up studies in the 1993 Pelotas (Brazil) birth cohort study: methodology and principal results  

PubMed Central

The aim of this study was to describe oral health follow-up studies nested in a birth cohort. A population-based birth cohort was launched in 1993 in Pelotas, Rio Grande do Sul State, Brazil. Two oral health follow-up studies were conducted at six (n = 359) and 12 (n = 339) years of age. A high response rate was observed at 12 years of age; 94.4% of the children examined at six years of age were restudied in 2005. The mean DMF-T index at age 12 was 1.2 (SD = 1.6) for the entire sample, ranging from 0.6 (SD = 1.1) for children that were caries-free at age six, 1.3 (SD = 1.5) for those with 1-3 carious teeth at six years, and 1.8 (SD = 1.8) for those with 4-19 carious teeth at six years (p < 0.01). The number of individuals with severe malocclusions at 12 years was proportional to the number of malocclusions at six years. Oral health problems in early adolescence were more prevalent in individuals with dental problems at six years of age. PMID:20963297

Peres, Marco A.; Barros, Aluísio Jardim; Peres, Karen Glazer; Araújo, Cora Luiza; Menezes, Ana M. B.; Hallal, Pedro C.; Victora, Cesar G.

2013-01-01

212

Risk factors for chronic kidney disease in a community-based population: a 10-year follow-up study  

Microsoft Academic Search

The purpose of this study was to explore risk factors affecting the incidence of chronic kidney disease (CKD) in general population. We conducted a 10-year follow-up study with 123 764 (male: 41 012, female: 82 752) adults aged 40 years and over who received community-based annual examinations. The primary outcome for the analysis was the development of CKD during the

K Yamagata; K Ishida; T Sairenchi; H Takahashi; S Ohba; T Shiigai; M Narita; A Koyama

2007-01-01

213

Family burden and coping strategies in schizophrenia: 1-year follow-up data from the BIOMED I study  

Microsoft Academic Search

Background: To date, only few data are available on how family burden in schizophrenia changes over time. In addition, no study has\\u000a explored how such factors as coping styles and social support influence burden over time. This paper presents the 1-year follow-up\\u000a data from the BIOMED I study on family burden and coping strategies in schizophrenia. Methods: A sample of

L. Magliano; G. Fadden; M. Economou; T. Held; M. Xavier; M. Guarneri; C. Malangone; C. Marasco; M. Maj

2000-01-01

214

Early Risk Factors for Depressive Symptoms among Korean Adolescents: A 6-to-8 Year Follow-up Study  

PubMed Central

Depression during adolescence is critical to the individual's own development. Hence, identifying individuals with high-risk depression at an early stage is necessary. This study aimed to identify childhood emotional and behavioral risk factors related to depressive symptoms in Korean adolescents through a longitudinal study. The first survey took place from 1998 to 2000, and a follow-up assessment conducted in 2006, as the original participants reached 13-15 yr of age. The first assessment used the Korean version of Child Behavior Checklist and a general questionnaire on family structure, parental education, and economic status to evaluate the participants. The follow-up assessment administered the Korean Children's Depression Inventory. Multiple regression analysis revealed that childhood attention problems predicted depressive symptoms during adolescence for both boys and girls. For boys, family structure also predicted adolescent depressive symptoms. This study suggests that adolescents with attention problems during childhood are more likely to experience depressive symptoms. PMID:24265533

Shin, Kyoung Min; Shin, Yun Mi; Park, Kyung Soon

2013-01-01

215

ARTHROSCOPIC SUBACROMIAL DECOMPRESSION FOR ADVANCED (STAGE II) IMPINGEMENT SYNDROME : A STUDY OF 52 PATIENTS WITH FIVE YEARS FOLLOW-UP  

Microsoft Academic Search

The authors report a prospective five-year follow-up study of 52 patients who had arthroscopic subacro- mial decompression for advanced (stage II : type 1 and 2) rotator cuff disease. All patients were assessed preoperatively, at six months and at five years post- operatively using the Constant-Murley score and the revised American Shoulder and Elbow Surgeons (ASES) score. From six months

K. DOM

216

Spinal cord lesions in patients with neuromyelitis optica: a retrospective long-term MRI follow-up study  

Microsoft Academic Search

Neuromyelitis optica (NMO) is characterised by a particular pattern of the optic nerves and the spinal cord. Long-term MRI\\u000a follow-up studies of spinal NMO lesions are rare, or limited by short observation periods. In nine patients with definite\\u000a NMO or recurrent longitudinally extensive transverse myelitis (LETM) with NMO-IgG serum antibodies, repeated MRI examinations\\u000a of the spine were carried out over

Wolfgang Krampla; Fahmy Aboul-Enein; Julia Jecel; Wilfried Lang; Elisabeth Fertl; Walter Hruby; Wolfgang Kristoferitsch

2009-01-01

217

Self-Determination and Positive Adult Outcomes: A Follow-Up Study of Youth with Mental Retardation or Learning Disabilities  

Microsoft Academic Search

There is increased emphasis on self -determination as an important outcome for youth with disabilities if they are to achieve positive adult outcomes after they leave school. However, the causal link between self-determination and positive adult outcomes has remained untested. The Arc conducted a follow-up study of students with mental retardation or learning disabilities for whom data regarding self-determination had

MICHAEL WEHMEYER; MICHELLE SCHWARTZ

218

Dietary diversity and subsequent mortality in the First National Health and Nutrition Examination Survey Epidemiologic Follow-up Study13  

Microsoft Academic Search

We examined the relation of dietary diversity to subsequent all-cause mortality by using data from the First National Health and Nutrition Examination Survey (NHANES I) Epidemiologic Follow-up Study, 1982- 1987. The analytic co- hort consisted of 4 160 men and 6264 women (including 2556 deaths), 25-74 y at baseline ( 197 1- 1975). Twenty-four-hour di- etary recalls were evaluated for

K Kant; Arthur Schatzkin; Gladys Block

219

The Insall-Burstein II prosthesis: A 5- to 9-year follow-up study in osteoarthritic knees  

Microsoft Academic Search

We prospectively studied 100 Insall-Burstein Posterior Stabilized II total knee arthroplasties (Zimmer Inc, Warsaw, IN) consecutively implanted in 91 patients with osteoarthritis. We reviewed 92 knees in 85 patients at a mean follow-up of 7.5 years (range, 5.3–9.5 years). According to the Knee Society score, 78 (85%) results were excellent, 11 (12%) were good, and 3 (3%) were fair or

P. F. Indelli; P. Aglietti; R. Buzzi; A. Baldini

2002-01-01

220

Long-term effects of bilateral subthalamic nucleus stimulation in advanced Parkinson disease: a four year follow-up study  

Microsoft Academic Search

In this study we aimed to investigate the effects of bilateral STN HFS in patients with advanced Parkinson disease (PD) at long-term, with a minimum follow-up of 4 years. Twenty patients (15 men, five women) were included, with a mean age of 60.9±8.1 years. Surgery was performed under local anesthesia. The target was defined on computerized tomography (CT). At 3

Veerle Visser-Vandewalle; Chris van der Linden; Yasin Temel; Halime Celik; Linda Ackermans; Geert Spincemaille; Jacques Caemaert

2005-01-01

221

Relationship between impairments, disability and handicap in reflex sympathetic dystrophy patients: a long-term follow-up study  

Microsoft Academic Search

Objective: To determine the relationship between impairments, disability and handicap in reflex sympathetic dystrophy (RSD) patients.Design: A long-term follow-up study of upper extremity RSD patients.Setting: A university hospital.Subjects: Sixty-five patients, 3–9 years (mean interval 5.5 years) after RSD of the upper extremity (mean age 50.2 years).Main outcome measures: Impairments: range of motion, moving two point discrimination, muscle strength of the

Jan Hb Geertzen; Pieter U Dijkstra; Eric Lp van Sonderen; Johan W Groothoff; Henk Jan ten Duis; Willem H Eisma

1998-01-01

222

A Fifty Year Mortality Follow-up Study of Veterans Exposed to Low Level Chemical Warfare Agent, Mustard Gas  

Microsoft Academic Search

PURPOSE: To determine if there is an increased risk of any cause specific mortality associated with low level mustard gas exposure among World War II Navy veterans.METHODS: A retrospective mortality follow-up study was conducted comparing the mortality of World War II Navy veterans who received low-level non-lethal exposures of mustard gas to that of World War II Navy veterans who

Tim Bullman; Han Kang

2000-01-01

223

Mobile phone text messaging and Telephone follow-up in type 2 diabetic patients for 3 months: a comparative study  

PubMed Central

Background To investigate and to compare the effectiveness of a nurse short message service (SMS) by cellular phone and telephone follow-up by nurse on Glycosylated hemoglobin (HbA1c) levels in people with type 2 diabetes. Methods Semi experimental study consisted of 77 patients with type 2 diabetes that randomly assigned to two groups: telephone follow-up (n?=?39) and short message service (n?=?38). Telephone interventions were applied by researcher for 3 months. SMS group that received message daily for 12 weeks. Data gathering instrument include data sheet to record HbA1c and questionnaire that consisted of demographic characteristics. Data gathering was performed at two points: initial the study and after 12 weeks. Data analyzed using descriptive and inferential statistics methods with SPSS version 11.5. Results Demographic variables were compared and all of them were homogenous. Results of this study showed that both interventions had significant mean changes in HbA1c; for the telephone group (p?=?0.001), with a mean change of ?0.93% and for the SMS group (p?=?0.001), with a mean change of ?1.01%. Conclusion Finding of this research showed that intervention using SMS via cellular phone and nurse-led-telephone follow up improved HbA1c for three months in type 2 diabetic patients and it can consider as alternative methods for diabetes control. PMID:23497735

2012-01-01

224

Loss to follow-up occurs at all stages in the diagnostic and follow-up period among HIV-infected patients in Guinea-Bissau: a 7-year retrospective cohort study  

PubMed Central

Objectives To describe loss to follow-up (LTFU) at all stages of the HIV programme. Design A retrospective cohort study. Setting The HIV clinic at Hospital National Simão Mendes in Bissau, Guinea-Bissau. Participants A total of 4080 HIV-infected patients. Outcome measures Baseline characteristics, percentages and incidence rates of LTFU as well as LTFU risk factors at four different stages: immediately after HIV diagnosis (stage 1), after the first CD4 cell count and before a follow-up consultation (stage 2), after a follow-up consultation for patients not eligible for antiretroviral treatment (ART; stage 3) and LTFU among patients on ART (stage 4). Results Almost one-third of the patients were lost to the programme before the first consultation where ART initiation is decided; during the 7-year observation period, more than half of the patients had been lost to follow-up (overall incidence rate=51.1 patients lost per 100 person-years). Age below 30?years at inclusion was a risk factor for LTFU at all stages of the HIV programme. The biggest risk factors were body mass index <18.5?kg/m2 (stage 1), male gender (stage 2), HIV-2 infection (stage 3) and CD4 cell count <200 cells/?L (stage 4). Conclusions In this study, LTFU constituted a major problem, and this may apply to other similar ART facilities. More than half of the patients were lost to follow-up shortly after enrolment, possibly implying a high mortality. Thus, retention should be given a high priority. PMID:24163204

Hønge, Bo Langhoff; Jespersen, Sanne; Nordentoft, Pernille Bejer; Medina, Candida; da Silva, David; da Silva, Zacarias José; Østergaard, Lars; Laursen, Alex Lund; Wejse, Christian

2013-01-01

225

Predictors of Risk-based Medical Follow-up: A Report from the Childhood Cancer Survivor Study1  

PubMed Central

Purpose To conduct an intervention study designed to assess the effectiveness of using a newsletter to increase medical follow-up in pediatric cancer survivors at risk of selected treatment complications. Methods Survivors participating in the Childhood Cancer Survivor Study who were at least 25 years of age and at risk of cardiovascular disease, breast cancer, or osteoporosis related to previous cancer treatment were randomly assigned to receive a newsletter featuring brief health risk information or a newsletter including an insert providing more comprehensive health risk information. A follow-up survey distributed 24 months after the newsletter intervention assessed predictors of medical follow-up. Results Overall there were no differences found among the groups in terms of access to a treatment summary, medical follow-up, discussion of childhood cancer health risks, and medical screening for the targeted health behaviors. One exception, indicating borderline significance was that women at risk for osteoporosis who received the newsletter insert were more likely to have discussed their risk with a doctor than those who only received the brief information (10.1% vs. 4.0% p=0.05). Discussion of breast cancer (OR=2.14; 95% CI=1.73–2.65), heart disease (OR=5.54; 95% CI=4.67–6.57) and osteoporosis (OR=7.87; 95% CI=6.34–9.78) risk with physician significantly predicted report of undergoing screening for targeted behavior in previous 2 years as did physician access to treatment summary. Conclusions More detailed content in a newsletter had minimal effect on recommended screening. However, survivor’s discussion of cancer-related risks with one’s doctor significantly influenced participation in health screening. These results highlight the integral role of communication in health behavior. PMID:23568405

Steele, Jeanne R.; Wall, Melanie; Salkowski, Nicholas; Mitby, Pauline; Kawashima, Toana; Yeazel, Mark W.; Hudson, Melissa M.; Robison, Leslie L.; Mertens, Ann C.

2013-01-01

226

Costs of remote monitoring vs. ambulatory follow-ups of implanted cardioverter defibrillators in the randomized ECOST study  

PubMed Central

Aims The Effectiveness and Cost of ICD follow-up Schedule with Telecardiology (ECOST) trial evaluated prospectively the economic impact of long-term remote monitoring (RM) of implantable cardioverter defibrillators (ICDs). Methods and results The analysis included 310 patients randomly assigned to RM (active group) vs. ambulatory follow-ups (control group). Patients in the active group were seen once a year unless the system reported an event mandating an ambulatory visit, while patients in the control group were seen in the ambulatory department every 6 months. The costs of each follow-up strategy were compared, using the actual billing documents issued by the French health insurance system, including costs of (i) (a) ICD-related ambulatory visits and transportation, (b) other ambulatory visits, (c) cardiovascular treatments and procedures, and (ii) hospitalizations for the management of cardiovascular events. The ICD and RM system costs were calculated on the basis of the device remaining longevity at the end of the study. The characteristics of the study groups were similar. Over a follow-up of 27 months, the mean non-hospital costs per patient-year were €1695 ± 1131 in the active, vs. €1952 ± 1023 in the control group (P = 0.04), a €257 difference mainly due to device management. The hospitalization costs per patient-year were €2829 ± 6382 and €3549 ± 9714 in the active and control groups, respectively (P = 0.46). Adding the ICD to the non-hospital costs, the savings were €494 (P = 0.005) or, when the monitoring system was included, €315 (P = 0.05) per patient-year. Conclusion From the French health insurance perspective, the remote management of ICD patients is cost saving. Clinical trials registration NCT00989417, www.clinicaltrials.gov PMID:24614572

Guédon-Moreau, Laurence; Lacroix, Dominique; Sadoul, Nicolas; Clémenty, Jacques; Kouakam, Claude; Hermida, Jean-Sylvain; Aliot, Etienne; Kacet, Salem

2014-01-01

227

Reexamination of Total Fluid Intake and Bladder Cancer in the Health Professionals Follow-Up Study Cohort  

PubMed Central

It has been hypothesized that high fluid intake may reduce contact time between carcinogens and bladder epithelium and consequently reduce carcinogenesis. Epidemiologic studies examining fluid intake and bladder cancer have been extremely inconsistent, ranging from strong inverse to strong positive associations. The authors reevaluated the association between fluid intake and bladder cancer among 47,909 participants in the prospective Health Professionals Follow-up Study over a period of 22 years. During follow-up (1986–2008), 823 incident bladder cancer cases were diagnosed. Information on fluid intake was collected by using the food frequency questionnaire at baseline and every 4 years thereafter. Cox proportional hazard regression analysis was used to adjust for risk factors for bladder cancer. Total fluid intake was inversely associated with bladder cancer when the analysis was based on the baseline diet (relative risk = 0.76, 95% confidence interval: 0.60, 0.97), comparing the highest total daily fluid intake quintile (>2,531 mL/day) with the lowest quintile (<1,290 mL/day) (Ptrend = 0.01). However, no association was detected when the analysis was based on recent diet or cumulative updated diet. The updated analysis for total fluid intake and bladder cancer was attenuated compared with the original findings from the first 10-year follow-up period. PMID:22355034

Zhou, Jiachen; Smith, Scott; Giovannucci, Edward; Michaud, Dominique S.

2012-01-01

228

Functional disability in medication management and driving among individuals with HIV: A 1-year follow-up study  

PubMed Central

Approximately 50% of individuals with HIV report cognitive deficits that can affect social or occupational functioning. The present study used a longitudinal design (1 year) to examine the relationship between cognitive factors and incidental functional deficits in medication management and driving ability among a cohort of 101 HIV+ participants. Participants were classified into groups of functionally “stable” and “disabled” for each laboratory-based functional task (i.e., Medication Management Task–Revised, MMT–R, and PC-based driving simulator). We hypothesized that participants who exhibited a functional deficit in either MMT–R or driving at follow-up assessment would demonstrate significantly poorer baseline cognitive performance at study entry than participants who remained functionally stable. As hypothesized, participants who demonstrated significantly lower baseline performance in learning/memory and executive functioning also demonstrated functional disability on the MMT–R at follow-up when compared to functionally stable participants. Poor baseline performance in speed of information processing was associated with a deficit in driving ability at follow-up assessment. Our results suggest that lower baseline cognitive functioning predicts downstream functional disability, and that deficits in learning/memory and information processing speed are particularly predictive of deficits in medication management and driving ability. PMID:23237014

Thames, April D.; Arentoft, Alyssa; Rivera-Mindt, Monica; Hinkin, Charles H.

2013-01-01

229

The siblings of childhood cancer patients need early support: a follow up study over the first year  

PubMed Central

Background and methods: In a 1 year follow up study, we assessed the life situation of 33 siblings of childhood cancer patients and 357 healthy controls. The hypothesis was that siblings have more behavioural and health related problems just after the cancer diagnosis. Validated assessment methods were used. Results: Siblings below school age tended to have conduct problems, psychosomatic problems, and a mixed group of other behavioural problems, when assessed 3 months after the cancer diagnosis. These symptoms became less evident during follow up. Among the school aged siblings, however, conduct problems, learning problems, psychosomatic problems, impulsive-hyperactive symptoms, and other behavioural symptoms remained unchanged during follow up. In their self assessments, the school aged siblings showed both state and trait anxiety more often than controls at the first assessment, but later these symptoms settled to the same level as the controls. The overall Children's Depression Inventory (CDI) depression scores did not show differences between the study groups. Conclusions: The ratings of the parents were in keeping with the self assessment of the school aged siblings only in a few aspects; the emphasis of findings can be changed when proxies are used. The siblings have symptoms and adverse feelings which probably could be relieved by targeted, early information about the illness, and possibly by group discussions or activities, soon after the cancer diagnosis. In order to obtain necessary support for the siblings with educational problems, school personnel need to be informed about the sibling distress. PMID:15499052

Lahteenmaki, P; Sjoblom, J; Korhonen, T; Salmi, T

2004-01-01

230

A 12-year follow-up study of psychiatric symptomatology among cocaine-dependent men  

Microsoft Academic Search

This prospective longitudinal study examines patterns of psychiatric symptomatology among men admitted to treatment for cocaine dependence in 1988–1989. Study participants were interviewed at treatment intake, and at 1 year, 2 years and 12 years after treatment. The Hopkins Symptom Checklist-58 (SCL) and Natural History Interview were administered at the 4 time points. Of the 266 study participants interviewed at

Diane M. Herbeck; Yih-Ing Hser; Ake T. H. Lu; M. Elena Stark; Alfonso Paredes

2006-01-01

231

Does Attrition during Follow-Up of a Population Cohort Study Inevitably Lead to Biased Estimates of Health Status?  

PubMed Central

Attrition is a potential source of bias in cohort studies. Although attrition may be inevitable in cohort studies of older people, there is little empirical evidence as to whether bias due to such attrition is also inevitable. Anonymised primary care data, routinely collected in clinical practice and independent of any cohort research study, represents an ideal unselected comparison dataset with which to compare primary care data from consenting responders to a cohort study. Our objective was to use this method as a novel means to assess if (i) responders at follow-up stages in a cohort study remain representative of responders at baseline and (ii) attrition biases estimates of longitudinal associations. We compared primary care consultation morbidities and prescription prevalences among circa 32,000 patients aged 50+ who contribute to an anonymised general practice database (Consultations in Primary Care Archive (CiPCA)) with those from patients aged 50+ in the North Staffordshire Osteoarthritis Project (NorStOP) cohort, United Kingdom (2002–2008; n?=?16,159). 8,197 (51%) persons responded to the NorStOP baseline survey and consented to medical record review. 5,121 and 3,311 responded at 3- and 6-year follow-ups. Differences in consulting prevalence of non-musculoskeletal morbidities between NorStOP responders and CiPCA comparison population did not increase over the two follow-up points except for ischaemic heart disease. Differences observed at baseline for osteoarthritis-related consultations were generally unchanged at the two follow-ups (standardised prevalence ratios for osteoarthritis (1.09–1.13) and joint pain (1.12–1.23)). Age and gender adjusted associations between baseline consultation for chronic morbidity and future new osteoarthritis and related consultations were similar in CiPCA (adjusted Hazard Ratio: 1.40; 95% Confidence Interval: 1.34,1.47) and NorStOP 6-year responders (1.32; 1.15,1.51). There was little evidence that responders at follow-ups represented any further selection bias to that present at baseline. Attrition in cohort studies of older people does not inevitably indicate bias. PMID:24386313

Lacey, Rosie J.; Jordan, Kelvin P.; Croft, Peter R.

2013-01-01

232

Evaluation of the Combined Application of Ultrasound Imaging Techniques for Middle Cerebral Artery Stent Surveillance and Follow-Up Study  

PubMed Central

Objective In recent years, cerebral artery stenting has become an effective method for the treatment of cerebral artery stenosis. However, methods for assessing efficacy and techniques for follow-up imaging still need to be developed. This study was designed to evaluate the application of transcranial color-coded sonography (TCCS) in assessing stenting of middle cerebral artery (MCA) stenosis. And, two new imaging techniques (vascular enhancement technology (VET) and 3-dimensional (3D) imaging) were tried out and evaluated. Method We enrolled 43 patients with cerebral artery stenosis for vascular stent implantation. All patients were examined by ultrasonography and confirmed through digital subtraction angiography. The stenosis was imaged and blood flow parameters were analyzed before and after the procedure using TCCS. VET and 3D imaging model were used in part of the patients. Important postoperative hemodynamic changes were noted. Results 1) Adequate stent image was present in 41 out of 43 patients as detected by postoperative 2-dimensional imaging. Images lacking clarity were obtained in 2 patients. 2) The perioperative and postoperative (one week follow-up) instantaneous blood flow velocity at the site of stenosis was significantly decreased (P<0.05) when compared with preoperative levels. Differences between postoperative (one week follow-up) and preoperative blood flow velocity were significant (P<0.05). Differences in blood flow velocity at long-term follow-up (six months and two years) compared to one-week values were not statistically significant (P>0.05). 3) VET imaging visualizes the MCA lumen and stent morphology clearly. 3D ultrasound can be used for imaging of the stent shape as well as its inner surface. Conclusion TCCD can be considered a quick and effective clinical detection method to evaluate the intracranial arterial hemodynamics changes before and after stenting treatment for MCA stenosis. New imaging technologies 3D and VET can achieve additional image information. PMID:24236130

Liu, Xi; Wang, Jia; Li, Li Hong; Deng, Jian Ping; Duan, Yun You

2013-01-01

233

Baccalaureate and Beyond Longitudinal Study: 1993/94 First Follow-Up Methodology Report. Technical Report.  

ERIC Educational Resources Information Center

The Baccalaureate and Beyond Longitudinal Study (B&B:93) tracks the experiences of a cohort of recent college graduates, those who received the baccalaureate degree during the 1992-93 academic year and were first interviewed as part of the National Postsecondary Student Aid Study. The experiences of this group in the areas of academic enrollment,…

Green, Patricia J.; And Others

234

Adjustment to University and Academic Performance: Brief Report of a Follow-Up Study  

ERIC Educational Resources Information Center

This study presents data that extend an earlier analysis of predictors of academic performance from one to three years. None of the adjustment and other psychosocial variables (help-seeking, academic motivation, self-esteem, perceived stress and perceived academic overload) could predict success at university at the end of three years of study.…

Petersen, Il-haam; Louw, Johann; Dumont, Kitty; Malope, Nomxolisi

2010-01-01

235

Ophthalmological follow up of preterm infants: a population based, prospective study of visual acuity and strabismus  

Microsoft Academic Search

BACKGROUND\\/AIMSPrematurely born infants are known to have an increased rate of ophthalmological morbidity. The aim of the present study was to investigate visual acuity and ocular alignment in a population of preterm infants in a geographical area, in infants with and without retinopathy of prematurity (ROP).METHODSA prospective population based study of ophthalmological status of preterm infants with a birth weight

G Holmström; M el Azazi; U Kugelberg

1999-01-01

236

Adjustment to Spinal Cord Injury: A Comprehensive Follow-Up Study.  

ERIC Educational Resources Information Center

This document reports a comprehensive followup study to describe postservice life status of former vocational rehabilitation clients and to develop an empirical index of postservice adjustment to spinal cord injury. Significant findings, conclusions, and implications are found at the beginning. The introduction section summarizes followup studies

Cook, Daniel; And Others

237

The Bounce Back Retention Program: One-Year Follow-Up Study  

ERIC Educational Resources Information Center

This study provides results regarding the effectiveness of the Bounce Back Retention Program (BBRP), a semester-long voluntary course for students on academic probation (AP). This is the first phase of a longitudinal study of spring 2007 freshmen at San Diego State University (SDSU). Results were analyzed for three samples: 1) "AP BBRP-Credit"…

Hanger, Maria Andujo; Goldenson, Julie; Weinberg, Marsha; Schmitz-Sciborski, Amy; Monzon, Reynaldo

2012-01-01

238

Follow-Up Studies of Students Who Stopped Out 1974-1981. Volume 12, No. 7.  

ERIC Educational Resources Information Center

Data were consolidated from 11 studies conducted at William Rainey Harper College (WRHC) between 1974 and 1981. The studies surveyed a total of 1,939 students, who left WRHC after attending at least one semester, to determine their educational objectives, current activities, employment characteristics, educational activities, and evaluation of…

Lucas, John A.

239

Students' Thinking and Alternative Conceptions of Transport Systems in Plants: A Follow-Up Study  

ERIC Educational Resources Information Center

The purpose of the study was to explore students' alternative conceptions and their associative thinking regarding internal transport in plants through administration of a refined diagnostic test. Questions of associative thinking and explanation were added to form a third tier of the previous two-tier test. The study found three terms related to…

Wang, Jing-Ru

2007-01-01

240

Association Between Body Mass Index and Colorectal Neoplasia at Follow-Up Colonoscopy: A Pooling Study  

Microsoft Academic Search

A direct relation between body mass index (BMI) and risk of colorectal adenomas and cancer has been reported, but few studies have had adequate sample size for conducting stratified analyses by sex, family history, colorectal subsite, or features of metachronous lesions. Data from 8,213 participants in 7 prospective studies of metachro- nous colorectal adenomas were pooled to assess whether the

Elizabeth T. Jacobs; Dennis J. Ahnen; Erin L. Ashbeck; John A. Baron; E. Robert Greenberg; Peter Lance; David A. Lieberman; Arthur Schatzkin; Patricia A. Thompson; Maria Elena Martinez

241

The course of dysphoric affective and cognitive states in borderline personality disorder: a 10-year follow-up study  

PubMed Central

The current study aimed to assess dysphoric states among 290 patients with borderline personality disorder (BPD) and 72 non-borderline axis II comparison subjects (OPD) over a 10-year course of prospective follow-up. Additionally, we assessed the severity of these states among borderline patients who had and had not recovered both symptomatically and psychosocially. The Dysphoric Affect Scale (DAS) – a 50-item self-report measure of affective and cognitive states thought to be common among borderline patients and specific to the disorder – was administered at five waves of prospective follow-up. Affective and cognitive DAS items were separately analyzed, yielding respective subscores. Borderline patients reported more severe dysphoric states compared to OPD subjects at baseline. However, the severity of affective and cognitive states declined significantly for both groups taken together over 10–years of follow-up. Within the BPD group, recovered subjects reported less severe dysphoric states compared to non-recovered subjects at baseline. Results also showed a significant decline in DAS scores over time, but at a greater rate for recovered subjects. In sum, while the severity of dysphoric states declines significantly over time, inner distress remains an area of vulnerability for borderline subjects. Additionally, the severity and pervasiveness of these states may affect recovery over time. PMID:22326877

Reed, Lawrence Ian; Fitzmaurice, Garrett; Zanarini, Mary C.

2011-01-01

242

Shifting Coresidence Near the End of Life: Comparing Decedents and Survivors of a Follow-Up Study in China  

PubMed Central

What we know about transitions in coresidence of elders in China is based on panel data involving survivors. This article examines the tendency to and determinants of shifts in coresidence with adult children among the very old, comparing survivors of an intersurvey period with those who died (decedents). Data come from the Chinese Longitudinal Healthy Longevity Survey. Baseline and follow-up surveys indicate shifts in coresidence, defined as change from not living with an adult child to living in the same household as an adult child, and the converse. Rates of shifting are adjusted for time to follow-up. Regressions examine predictors of shifts among four groups: baseline coresident and noncoresident survivors and decedents. Decedents and noncoresidents are more likely to shift than survivors and coresidents. Covariates related to physical and material need as well as marital status are the strongest predictors of shift. Thus, the needs of a very old person dominate coresidential shifts and stability, lending support to an altruistic notion of living arrangement decision making. In the end, we conclude that the period nearing the end of life is a time of flux in living situation and that coresidential shifts are underestimated when those who die during a follow-up study are ignored. PMID:20879676

ZIMMER, ZACHARY; KORINEK, KIM

2010-01-01

243

The course of dysphoric affective and cognitive states in borderline personality disorder: a 10-year follow-up study.  

PubMed

The current study aimed to assess dysphoric states among 290 patients with borderline personality disorder (BPD) and 72 non-borderline axis II comparison subjects other personality disorders, (OPD) over a 10-year course of prospective follow-up. Additionally, we assessed the severity of these states among borderline patients who had and had not recovered both symptomatically and psychosocially. The Dysphoric Affect Scale (DAS) - a 50-item self-report measure of affective and cognitive states thought to be common among borderline patients and specific to the disorder - was administered at five waves of prospective follow-up. Affective and cognitive DAS items were separately analyzed, yielding respective subscores. Borderline patients reported more severe dysphoric states compared to OPD subjects at baseline. However, the severity of affective and cognitive states declined significantly for both groups taken together over 10 years of follow-up. Within the BPD group, recovered subjects reported less severe dysphoric states compared to non-recovered subjects at baseline. Results also showed a significant decline in DAS scores over time, but at a greater rate for recovered subjects. In sum, while the severity of dysphoric states declines significantly over time, inner distress remains an area of vulnerability for borderline subjects. Additionally, the severity and pervasiveness of these states may affect recovery over time. PMID:22326877

Reed, Lawrence Ian; Fitzmaurice, Garrett; Zanarini, Mary C

2012-03-30

244

Clinical study of flap design to increase the keratinized gingiva around implants: 4-year follow-up.  

PubMed

Since the presence of keratinized gingiva is so important for peri-implant outcome, the aim of this study is to describe a partial thickness flap design to increase the amount of keratinized peri-implant tissue as well as its thickness. A total of 131 implants were placed in 85 patients: 103 implants (78.63%) in the mandible and 28 implants (21.37%) in the maxilla. Before implant placement in edentulous ridge the residual keratinized mucosa usually was measured with a periodontal probe in a buccal-palatal direction. A palatal or lingual incision was made to raise a partial thickness flap with the residual keratinized tissue. After implant placement the flap was apically repositioned and secured with loose periosteal sutures. Keratinized tissue levels were calculated at baseline, at 6 months, and every year follow-up. Measurements were reported for each implant diameter. At 4-year follow-up, implant survival rate of 87.79% was reported. Peri-implant keratinized mucosa confirmed clinical gain in all cases; mean levels at 1- and 4-year follow-ups were 7.26 ± 2.01 mm and 7.37 ± 2.12 mm, respectively. The levels remained stable over time. This flap design allows immediate correction of adaptation of the keratinized tissue around the implant, increasing the thickness and amount of the keratinized tissue. PMID:25106011

Bruschi, Giovanni B; Crespi, Roberto; Capparé, Paolo; Gherlone, Enrico

2014-08-01

245

Severe deep white matter lesions and outcome in elderly patients with major depressive disorder: follow up study  

PubMed Central

Objective To determine the difference in outcome among elderly people with major depression who do and do not have severe white matter lesions on magnetic resonance imaging. Design Follow up study. Setting Two psychiatric and two general hospitals in Melbourne, Australia. Subjects 60 depressed subjects aged over 55 referred to hospital psychiatric services with major depressive disorder meeting American Psychiatric Association (DSM-IIIR) criteria. Main outcome measure Proportion with good outcome as determined by full recovery from initial illness and no evidence of depressive relapse or cognitive decline during follow up among those with and without lesions. Results Mean (SD) follow up was 31.9 (9.9) months. Survival analysis showed a significant effect of severe lesions on time to poor outcome (P=0.04), with median survival 136 days in those with severe lesions compared with 315 days in those without. Conclusion Severe white matter change on magnetic resonance imaging is associated with poor outcome in elderly depressed subjects. Key messagesSevere deep white matter lesions on magnetic resonance imaging are common in elderly patients with depressionPatients with these lesions are at greater risk of poor long term outcome (chronicity and relapse) than those without lesionsThe neuropathogical and neurochemical correlates of these white matter changes need investigation PMID:9765166

O’Brien, John; Ames, David; Chiu, Edmond; Schweitzer, Isaac; Desmond, Patricia; Tress, Brian

1998-01-01

246

Persistent asthma due to isocyanates. A follow-up study of subjects with occupational asthma due to toluene diisocyanate (TDI)  

SciTech Connect

Thirty-five subjects with occupational asthma due to toluene diisocyanate (TDI) exposure were examined. All the subjects were studied with inhalation challenges with TDI and with methacholine. TDI asthma was documented by a positive inhalation challenge to low levels of TDI. Airway responsiveness to methacholine was in the range of asthmatic patients at the time of diagnosis. After an average follow-up interval of 10 months, all the subjects were re-examined. Of the 35 subjects examined, 30 subjects (85.7%) left the workplace, and 5 remained in the same job. Twenty-seven subjects (77.1%) continued to have asthmatic attacks requiring medication for relief of symptoms. At follow-up examination, TDI asthma was documented by a positive inhalation challenge to TDI in 27 subjects. Of these 27 TDI reactors, 22 subjects were removed from occupational exposure to TDI. The TDI reactors had persistent respiratory symptoms and airway hyperresponsiveness to methacholine. At follow-up visit, 8 subjects (22.9%) lost sensitization to TDI; 5 subjects (62.5%) in this group had also normal airway responsiveness to methacholine after removal from exposure. Only 1 subject among the TDI nonreactors complained of mild respiratory symptoms. At diagnosis, there were no significant differences between subjects who recovered and those who did not with regard to age, smoking habits, atopy, duration of exposure to isocyanates, duration of symptoms, baseline FEV1 (% pred), and baseline airway responsiveness to methacholine.

Mapp, C.E.; Corona, P.C.; De Marzo, N.; Fabbri, L.

1988-06-01

247

Prospective two year follow up study comparing novel and conventional imaging procedures in patients with arthritic finger joints  

PubMed Central

Objective: To carry out a prospective two year follow up study comparing conventional radiography, three-phase bone scintigraphy, ultrasonography (US), and three dimensional (3D) magnetic resonance imaging (MRI) with precontrast and dynamic postcontrast examination in detecting early arthritis. The aim of the follow up study was to monitor the course of erosions during treatment with disease modifying antirheumatic drugs by different modalities and to determine whether the radiographically occult changes like erosive bone lesions of the finger joints detected by MRI and US in the initial study would show up on conventional radiographs two years later. Additionally, to study the course of soft tissue lesions depicted in the initial study in comparison with the clinical findings. Methods: The metacarpophalangeal, proximal interphalangeal, and distal interphalangeal joints (14 joints) of the clinically more severely affected hand (soft tissue swelling and joint tenderness) as determined in the initial study of 49 patients with various forms of arthritis were examined twice. The patients had initially been divided into two groups. The follow up group I included 28 subjects (392 joints) without radiographic signs of destructive arthritis (Larsen grades 0–1) of the investigated hand and wrist, and group II (control group) included 21 patients (294 joints) with radiographs showing erosions (Larsen grade 2) of the investigated hand or wrist, or both, at the initial examination. Results: (1) Radiography at the two year follow up detected only two erosions (two patients) in group I and 10 (nine patients) additional erosions in group II. Initial MRI had already detected both erosions in group I and seven (seven patients) of the 10 erosions in group II. Initial US had depicted one erosion in group I and four of the 10 erosions in group II. (2) In contrast with conventional radiography, 3D MRI and US demonstrated an increase in erosions in comparison with the initial investigation. (3) The abnormal findings detected by scintigraphy were decreased at the two year follow up. (4) Both groups showed a marked clinical improvement of synovitis and tenosynovitis, as also shown by MRI and US. (5) There was a striking discrepancy between the decrease in the soft tissue lesions as demonstrated by clinical findings, MRI, and US, and the significant increase in erosive bone lesions, which were primarily evident at MRI and US. Conclusions: Despite clinical improvement and a regression of inflammatory soft tissue lesions, erosive bone lesions were increased at the two year follow up, which were more pronounced with 3D MRI and less pronounced with US. The results of our study suggest that owing to the inadequate depiction of erosions and soft tissue lesions, conventional radiography alone has limitations in the intermediate term follow up of treatment. US has a high sensitivity for depicting inflammatory soft tissue lesions, but dynamic 3D MRI is more sensitive in differentiating minute erosions. PMID:12228160

Backhaus, M; Burmester, G; Sandrock, D; Loreck, D; Hess, D; Scholz, A; Blind, S; Hamm, B; Bollow, M

2002-01-01

248

Treatment Compliance of Adolescents after Attempted Suicide: A 2-Year Follow-Up Study  

ERIC Educational Resources Information Center

The study investigates compliance with mental health treatments among suicidal adolescents. Results show that child psychopathology and parental attitudes toward treatment plays an important part in increasing compliance with mental health treatment for adolescent suicide attempters.

Burns, Craig D.; Cortell, Ranon; Wagner, Barry M.

2008-01-01

249

Early Dexamethasone Therapy in Preterm Infants: A Follow-up Study  

Microsoft Academic Search

Objectives. To study the outcome at 2-year corrected age of infants who participated in a double-blind controlled trial of early (<12 hours) dexa- methasone therapy for the prevention of chronic lung disease (CLD). Methods and Materials. A total of 133 children (70 in the control group, 63 in the dexamethasone-treated group) who survived the initial study period and lived to

S. Hsieh; Yu J. Lien; Tsu F. Yeh; Yuh J. Lin; Chao C. Huang; Yung J. Chen; Chyi H. Lin; Hong C. Lin

250

Psychotropic drug use among people with dementia – a six-month follow-up study  

PubMed Central

Background Psychotropic drugs are widely used among old people with dementia but few studies have described long-term treatment in this group of patients. The purpose of this study was to explore the long-term use of psychotropic drugs in old people with dementia. Methods Data on psychotropic drug use, functioning in the activities of daily living (ADL), cognitive function and behavioral and psychological symptoms were collected at baseline and six months later, using the Multi-Dimensional Dementia Assessment Scale (MDDAS). The data were collected in 2005–2006. Detailed data about the prescribing of psychotropic drugs were collected from prescription records. This study was conducted in 40 specialized care units in northern Sweden, with a study population of 278 people with dementia. Results At the start of the study, 229 of the participants (82%) were prescribed at least one psychotropic drug; 150 (54%) used antidepressants, 43 (16%) used anxiolytics, 107 (38%) used hypnotics and sedatives, and 111 (40%) used antipsychotics. Among the baseline users of antidepressants, anxiolytics, hypnotics and sedatives and antipsychotics, 67%, 44%, 57% and 57% respectively, still used the same dose of the same psychotropic drug after six months. Associations were found between behavioral and psychological symptoms and different psychotropic drugs. Conclusion Psychotropic drug use was high among people with dementia living in specialized care units and in many cases the drugs were used for extended periods. It is very important to monitor the effects and adverse effects of the prescribed drug in this frail group of people. PMID:24196341

2013-01-01

251

Pubertal Timing and Substance Use in Middle Adolescence: A 2-Year Follow-Up Study  

ERIC Educational Resources Information Center

Earlier research has associated early puberty with emotional and behavioral symptoms particularly among girls, while among boys, findings have been contradictory as to whether risks are associated with early or late pubertal timing. We studied the association between pubertal timing and substance use behaviors in middle adolescence in a 2-year…

Kaltiala-Heino, Riittakerttu; Koivisto, Anna-Maija; Marttunen, Mauri; Frojd, Sari

2011-01-01

252

1994 Follow-Up Study of Fiscal Year 1993 Occupational Program Graduates.  

ERIC Educational Resources Information Center

In March 1994, a study was conducted to determine the perspectives of Illinois community college graduates regarding their preparation for employment, their continuing education goals, and their satisfaction with their major and college services. A total of 6,245 occupational program graduates, including graduates of agriculture; conservation and…

Illinois Community Coll. Board, Springfield.

253

Adolescent and adult leisure patterns: A 37?year follow?up study  

Microsoft Academic Search

The relationship between adolescent and adult leisure activities was assessed by utilizing longitudinal data from 1298 subjects studied during their high school years and again when they were in their early fifties. For the sample members, the greater the involvement in a specific type of activity during adolescence, the more frequent the participation in the same type of activity at

David Scott; Fern K. Willits

1989-01-01

254

Motor cortex excitability in Alzheimer disease: one year follow-up study  

Microsoft Academic Search

Seventeen patients affected by Alzheimer disease (AD) underwent two transcranial magnetic stimulation (TMS) studies separated by an interval of 12 months, in order to monitor possible changes in motor cortex excitability. After the first examination, all patients were treated with cholinesterase inhibitor drugs. Motor threshold (MT), amplitude of motor evoked potentials and central motor conduction time were considered. After one

Giovanni Pennisi; Giovanna Alagona; Raffaele Ferri; Salvatore Greco; Domenico Santonocito; Alessandra Pappalardo; Rita Bella

2002-01-01

255

A 2-year follow-up study of work ability among college educators  

Microsoft Academic Search

The aim of this study was to evaluate work ability among college educators before and after an intervention at the workplace. An administrative restructuring in the workplace started to be implemented in 2005. The work ability index (WAI) was administered to 154 educators before the restructure in 2004 and to 60 educators following the restructure in 2006. A t-test comparing

Elaine C. Marqueze; Gustavo P. Voltz; Flávio N. S. Borges; Claudia R. C. Moreno

2008-01-01

256

New Teachers' Perceptions on Their Preparation: A Follow-Up Study  

ERIC Educational Resources Information Center

This research investigated new public school teachers' perceptions of their level of preparation in the area classroom management and how prepared they were during their first year of teaching to handle various classroom and discipline issues. The study updated research done on this topic that used a 1999-2000 public school teacher dataset…

Powers, Kristi J.

2012-01-01

257

A Follow-Up Study of Patient-Instructors Who Teach the Pelvic Examination.  

ERIC Educational Resources Information Center

The teaching of the pelvic examination is seen as having undergone a dramatic change since the introduction of trained professional patient-instructors. The results of a study using two groups, the professional patient-instructor method in one group and a control group using gynecologists and clinic patients, is presented. (MLW)

And Others; Livingstone, Ronald A.

1980-01-01

258

Cognitive Deficits Associated with Acquired Amusia after Stroke: A Neuropsychological Follow-Up Study  

ERIC Educational Resources Information Center

Recent evidence on amusia suggests that our ability to perceive music might be based on the same neural resources that underlie other higher cognitive functions, such as speech perception and spatial processing. We studied the neural correlates of acquired amusia by performing extensive neuropsychological assessments on 53 stroke patients with a…

Sarkamo, Teppo; Tervaniemi, Mari; Soinila, Seppo; Autti, Taina; Silvennoinen, Heli M.; Laine, Matti; Hietanen, Marja

2009-01-01

259

Follow-Up Study of Rural Schools Implementing CSR Programs in the Southwest. Research Report.  

ERIC Educational Resources Information Center

Case studies of five small and isolated rural schools in the Southwest focused on their ability to fully implement Comprehensive School Reform Demonstration (CSR) programs over the 3-year period of their federal grants. Data were gathered via interviews with school personnel, classroom observations, document reviews, and telephone interviews with…

Carlson, Robert V.

260

Surgical Management of Achilles Tendon Overuse InjuriesA Long-term Follow-up Study  

Microsoft Academic Search

We studied 79 cases of surgically treated Achilles ten don overuse injuries in 66 patients. Fifty-three (80%) of these patients were competitive or serious recreational runners operated on between 1978 and 1991. There were 49 men and 17 women with a mean age of 33 years (range, 17 to 59). The cases were divided into surgical subgroups based on their

Anthony A. Schepsis; Clayton Wagner; Robert E. Leach

1994-01-01

261

Follow-up Prostate Cancer Treatments After Radical Prostatectomy: a Population-Based Study  

Microsoft Academic Search

Background: Radical prostatectomy is one of the most com- monly used curative procedures for the treatment of local- ized prostate cancer. The probability that a patient will undergo additional cancer therapy after this procedure is largely unknown. Purpose: The objective was to determine the likelihood of additional cancer therapy after radical prostatectomy. Methods: Data for this study were derived from

Grace L. Lu-Yao; Arnold L. Potosky; Peter C. Albertsen; John H. Wasson; Michael J. Barry; John E. Wennberg

262

A Follow Up Study of Bowling Green Learning Center Students. PREPS Research Project, 1980-1981.  

ERIC Educational Resources Information Center

A study was conducted to evaluate the Adult Learning Center (ALC) of the Bowling Green (Kentucky) School System. The ALC is the part of the Bowling Green School System responsible for educating adults and teenagers with special circumstances which make enrollment in the regular public schools inappropiate. The program is individualized, with…

Abram, Marie J.; Esters, George

263

Relations between Achievement Goal Orientations and Math Achievement in Primary Grades: A Follow-Up Study  

ERIC Educational Resources Information Center

The aim of the present study was to investigate children's achievement goal orientations and their relations to math achievement in the primary grades. The sample consisted of 179 children who were in the 2nd and 3rd grades during the first measurement and in the 3rd and 4th grades during the second measurement. Children's self-ratings were…

Magi, Katrin; Lerkkanen, Marja-Kristiina; Poikkeus, Anna-Maija; Rasku-Puttonen, Helena; Kikas, Eve

2010-01-01

264

A Follow-Up Study on Learning Styles: Using Research To Facilitate Educational Excellence.  

ERIC Educational Resources Information Center

Cognitive style indicates how a learner thinks and responds to the environment. Cognitive styles of education majors appear to have an impact on performance in preservice education coursework. This study classifies as field dependent or field independent the cognitive styles of 537 education majors at Auburn University (Montgomery, Alabama) and…

Wieseman, Robert A.; And Others

265

A Follow-Up Study to Compare Success Rates of Developmental Math Students  

ERIC Educational Resources Information Center

This article presents a study that compared the success rates of students in Arithmetic (MTH 02), Algebra I (MTH 03), and Algebra II (MTH 03) when they were offered at Southwest Virginia Community College (SWCC) for three credits versus five credits. The authors' findings showed no significant differences in the success rates of students who were…

Woodard, Teresa; Burkett, Sexton

2010-01-01

266

Psychological follow-up study of 5-year-old ICSI children  

Microsoft Academic Search

BACKGROUND: The developmental outcomes of children born after ICSI are still a matter of concern. The purpose of the present study was to investigate psychological outcomes for 5-year-old children born after ICSI and compare these with outcomes for children born after spontaneous conception (SC). METHODS: Three hundred singleton children born after ICSI in Belgium, Sweden and the USA were matched

I. Ponjaert-Kristoffersen; T. Tjus; J. Nekkebroeck; J. Squires; D. Verte; M. Heimann

2004-01-01

267

A clinical and statistical follow-up study of atrophic gastritis  

Microsoft Academic Search

A study was made of 363 patients 11 to 18 years after initial biopsies and gastric secretory findings. Investigation of the cause of death revealed the development of gastric carcinoma in 13% of the cases which had prior findings of atrophic gastritis. Statistical analysis of the cases led to additional evidence that atrophic gastritis may constitute a predisposition for the

R. Cheli; G. Ciancamerla

1973-01-01

268

Coping with Serious Accidental Injury: A One-Year Follow-Up Study  

Microsoft Academic Search

Background: The aim of this study was to analyze changes of coping strategies in severely injured accident victims over time and to compare patients with high and low posttraumatic stress disorder (PTSD) symptom levels with regard to their coping patterns and accident-related cognitions. Methods: 106 consecutive patients with severe accidental injuries admitted to a trauma surgery intensive care unit (ICU)

Urs Hepp; Hanspeter Moergeli; Stefan Büchi; Lutz Wittmann; Ulrich Schnyder

2005-01-01

269

Conducting a Follow-Up Study of Students in Writing Courses.  

ERIC Educational Resources Information Center

Recognizing the need to assess the long term effects of composition instruction, a study was conducted to determine whether students could remember significant aspects of a writing course up to two years later, to discern their assessment of the effects of the course on their subsequent writing attitudes, and to solicit suggestions based on…

Smith, Eugene

270

Spontaneous abortions among dental assistants, factory workers, painters, and gardening workers: a follow up study.  

PubMed

This investigation was conducted to test the hypothesis that exposure of pregnant women to chemicals increases the risk of spontaneous abortion. The chemical risk factors under study to which dental assistants, factory workers, painters, and gardening workers were exposed were nitrous oxide, inorganic mercury, organic solvents, and pesticides. The study was carried out within the Danish county of Funen. It included all dental assistants employed in private or public dentistry. A comparable reference group was made up by employees less exposed to chemicals. Further study groups included all women painters within the county, women factory workers from selected factories, and about 50% of the women gardening workers within the county. Shop assistants and packers formed their control group. Information was obtained through a postal questionnaire study in May 1980 and from hospital records. Only among factory workers and painters was the odds ratio of spontaneous abortion found to be significantly increased. Neither among these women nor among dental assistants and gardening workers, however, was the reported exposure to any single chemical during pregnancy associated with a significantly increased odds ratio of spontaneous abortion. PMID:6747515

Heidam, L Z

1984-06-01

271

Public University Baccalaureate Follow-Up Study. May 2011 [Revised Feb 2012  

ERIC Educational Resources Information Center

This report provides the results of analysis of more than 40,000 students who received baccalaureate degrees from the public baccalaureate institutions in Washington during the 2005-06 and 2006-07 academic years. The purpose of this study was to follow students after graduation to determine the extent to which degree recipients were able to secure…

Washington Higher Education Coordinating Board, 2012

2012-01-01

272

A Follow-Up Study of Learning Disabled Programs in California Community Colleges.  

ERIC Educational Resources Information Center

A study was conducted to identify and describe the programs and services offered by California community colleges to meet the needs of learning disabled average (LDA) students. The survey of 106 California community colleges sought information on program characteristics, and on the identification and assessment methods employed by the colleges.…

Ostertag, Bruce A.; Baker, Ronald E.

273

The Breast Cancer Detection Demonstration Project (BCDDP) Follow-up Study  

Cancer.gov

Study subjects were participants in the Breast Cancer Detection Demonstration Project (BCDDP), a breast cancer screening program conducted between 1973 and 1980. Sponsored by the American Cancer Society and the NCI, the BCDDP provided up to five annual breast examinations to 283,222 women at 29 screening centers in 27 cities throughout the United States.

274

Emotional Psychopathology and Increased Adiposity: Follow-Up Study in Adolescents  

ERIC Educational Resources Information Center

Based on data from a three-year longitudinal study, we assess the effect, according to gender, of emotional psychopathology in preadolescence on anthropometric and body composition parameters in adolescence (N = 229). Psychopathology was assessed using the "Screen for Childhood Anxiety and Related Emotional Disorders, the Children's Depression…

Aparicio, Estefania; Canals, Josefa; Voltas, Nuria; Hernandez-Martinez, Carmen; Arija, Victoria

2013-01-01

275

Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up  

Microsoft Academic Search

Deep brain stimulation (DBS) is associated with significant improvement of motor complications in patients with severe Parkinson's disease after some 6-12 months of treatment. Long-term results in a large number of patients have been reported only from a single study centre. We report 69 Parkinson's disease patients treated with bilateral DBS of the subthalamic nucleus (STN, n= 49) or globus

M. C. Rodriguez-Oroz; J. A. Obeso; A. E. Lang; J.-L. Houeto; P. Pollak; S. Rehncrona; J. Kulisevsky; A. Albanese; J. Volkmann; M. I. Hariz; N. P. Quinn; J. D. Speelman; J. Guridi; I. Zamarbide; A. Gironell; J. Molet; B. Pascual-Sedano; B. Pidoux; A. M. Bonnet; Y. Agid; J. Xie; A.-L. Benabid; A. M. Lozano; J. Saint-Cyr; L. Romito; M. F. Contarino; M. Scerrati; V. Fraix; N. Van Blercom

2005-01-01

276

Coeliac Disease and Gluten-Free Diet: A Following-Up Study of Fifteen Young Adults  

Microsoft Academic Search

Fifteen patients with coeliac disease diagnosed in infancy and early childhood between 1959 and 1971 were included in the study. The primary diagnosis was made on the basis of typical symptoms and signs, stool examination for fat, xylose test and clinical and laboratory improvement after introduction of gluten-free diet. All patients were challenged with gluten for a minimum of 4

Hilde Thørnquist; Gaute Sandhei Jacobsen; Lauritz Bredrup Dahl; Gudmund Marhaug

1993-01-01

277

Where Are They Now? Lessons from a Single District Follow-Up Study  

ERIC Educational Resources Information Center

This study examined the postsecondary outcomes of students with and without disabilities in the four major outcomes areas of post-secondary education, employment, independent living, and recreation and leisure. The target population included students graduating from one mid-sized school district from a southern state. A stratified random sample of…

Williams-Diehm, Kendra L.; Benz, Michael R.

2008-01-01

278

Follow up study of near infrared (1100 to 1319 nm) retinal damage thresholds and trends  

NASA Astrophysics Data System (ADS)

A study of retinal damage thresholds in non-human primates (NHP) in the near-infrared (NIR) wavelengths of 1110, 1130, 1150, and 1319 nm has recently been reported. The progression of damage in retinal areas that received exposures below, greater than, and at threshold values for each respective wavelength are compared. Subjects were imaged using an Adaptive Optics (AO) enhanced Spectral Domain Optical Coherence Tomographer (SD-OCT) a year post laser exposure to examine damage characteristics and localization. The subject's retinas within the study exhibited a delayed response to NIR exposures in that many of the lesions that were not visible at the 1-hour observation period continued to grow in size over the 24-hour period and or became visible. Thermal lensing is believed to play a significant role in the formation or retinal lesions in the NIR and may explain the delayed response.

Pocock, Ginger M.; Oliver, Jeff W.; Noojin, Gary D.; Schuster, Kurt J.; Stolarski, David; Shingledecker, Aurora; Rockwell, Benjamin A.

2010-02-01

279

Cricoid webs--incidence and follow-up study in Indian patients.  

PubMed Central

A study was conducted to investigate the association of anaemia with dysphagia and cricoid webs in an adult Indian hospital population of 2,840 patients (1,200 males and 1,640 females). There were 150 cases (5.2%) of anaemia in the total population studied. One hundred and seventeen patients suffered from iron deficiency anaemia and only 33 from non-iron deficiency anaemia. Dysphagia was present in 15 patients (13%) of those with iron deficiency. Six (40%) of these cases of iron deficiency with dysphagia had cricoid webs. None of the cases with non-iron deficiency anaemia or the control population had either dysphagia or cricoid webs. Iron therapy improved four out of the six patients of iron deficiency with cricoid webs both subjectively and objectively. PMID:6739392

Khosla, S. N.

1984-01-01

280

5-year follow-up of a prospective clinical study on various types of core restorations  

Microsoft Academic Search

PURPOSE: This study tested whether: (1) the survival rate of cast post-and-core restorations is better than the survival of direct post-and-core restorations and post-free all-composite cores; and (2)the survival of these buildup restorations is influenced by the remaining dentin height after preparation. MATERIALS AND METHODS: In a clinical trial, 18 operators made 319 core restorations in 249 patients. The restorations

N. H. J. Creugers; A. G. B. Mentink; W. A. Fokkinga; C. M. Kreulen

2005-01-01

281

Relations Between Achievement Goal Orientations and Math Achievement in Primary Grades: A Follow?Up Study  

Microsoft Academic Search

The aim of the present study was to investigate children’s achievement goal orientations and their relations to math achievement in the primary grades. The sample consisted of 179 children who were in the 2nd and 3rd grades during the first measurement and in the 3rd and 4th grades during the second measurement. Children’s self?ratings were obtained on their goal orientations,

Katrin Mägi; Eve Kikas

2010-01-01

282

Young adult outcome of attention deficit hyperactivity disorder: a controlled 10-year follow-up study  

Microsoft Academic Search

Background. Our objective was to estimate the lifetime prevalence of psychopathology in a sample of youth with and without attention deficit hyperactivity disorder (ADHD) through young adult- hood using contemporaneous diagnostic and analytic techniques. Method. We conducted a case-control, 10-year prospective study of ADHD youth. At baseline, we assessed consecutively referred male, Caucasian children with (n=140) and without (n=120) DSM-

JOSEPH BIEDERMAN; MICHAEL C. MONUTEAUX; ERIC MICK; THOMAS SPENCER; TIMOTHY E. WILENS; JULIE M. SILVA; LINDSEY E. SNYDER; STEPHEN V. FARAONE

2006-01-01

283

The development of hepatocellular carcinoma from liver cirrhosis during a follow-up study  

Microsoft Academic Search

Summary  A prospective study was carried out in 126 cases with liver cirrhosis attending the outpatient clinic of Hepatology of the\\u000a Department of Internal Medicine, Dr. Cipto Mangunkusmo Hospital Jakarta, between August 1,1982 and Dec. 31, 1985. The patients\\u000a consisted of 82 men and 44 women and there were 45 HBsAg positive cases (36.7%). HBeAg was posotive in 35.6% (16\\/45) and

H. Ali Sulaiman

1989-01-01

284

Energy and macronutrient intake in adolescent sprint athletes: A follow-up study  

Microsoft Academic Search

Macronutrient intake, height, weight, and body composition of 60 adolescent sprint athletes were estimated every 6 months over 3 years. Seven-day food records were analysed based on the Belgian and Dutch food databanks. The age of participants at the start of the 3-year study was 14.8 ± 1.6 years for female athletes and 14.7 ± 1.9 years for male athletes. Girls and boys gained

Dirk Aerenhouts; Peter Deriemaeker; Marcel Hebbelinck; Peter Clarys

2011-01-01

285

Longitudinal pulmonary functional loss in cotton textile workers: A 5-year follow-up study  

PubMed Central

Background Occupational exposure to cotton dust causes several diseases affecting the lungs, but only limited information is available on effects of long-term exposure. In this study, we aimed to evaluate longitudinal changes in selected parameters of pulmonary function in textile workers. Material/Methods This prospective cohort study began with 196 textile workers in 2006 and was completed in 2011 with 49 workers. We used standardized tests for pulmonary function on participants on the first day of the workweek in June of 2006 and 2011. Environmental samples of cotton dust were gathered with a vertical elutriator. Loss of pulmonary function was assessed based on gender and smoking status. Results The mean number of years participants worked in the textile factory was 7.61±1.83 years, and the mean age was 35.3+5.8 years. The annual FEV1 loss of all workers was 53.2 ml, giving a ratio of annual FEV1 loss to baseline FEV1 of 1.4%. Pulmonary function parameters of all participants in 2011 were significantly lower than those in 2006 (for all, p<0.05). In both surveys, pulmonary function in current smokers was lower, but this difference was not significant (p>0.05). Conclusions This study provides the first data on pulmonary functional loss in Turkish textile workers and supports the findings of other cohort studies that workers with long-term exposure to cotton dust may lose some pulmonary function. The ratio of annual FEV1 loss to baseline FEV1 appears to be a more accurate and comparable method than annual FEV1 loss for evaluating pulmonary functional loss. PMID:24346118

Kahraman, Hasan; Sucakli, Mustafa Haki; Kilic, Talat; Celik, Mustafa; Koksal, Nurhan; Ekerbicer, Hasan Cetin

2013-01-01

286

Follow-up studies of children born after frozen sperm donation.  

PubMed

The need to assess the health of children born after assisted reproductive technologies (ART) using frozen donor spermatozoa has been a major concern for the last decade. Most available published studies are confusing (since they are retrospective) and refer to small numbers of cases or involve a bias. Two prospective and large population-based studies have been published, one in France and the other in Australia. The general characteristics of children born after ART using frozen spermatozoa was unchanged in comparison with the general population (weight, prematurity, stillbirths, sex ratio). However, the rate of multiple pregnancy was increased, first in artificial insemination with donor semen (AID), where the use of hormonal treatment may be too heavily prescribed, and second in IVF with donor semen (IVF/D) where both the ovulation induction treatments and embryo transfer policy increase the rate of multiple pregnancies. As far as birth defects or chromosomal abnormalities are concerned, no difference has been observed from the general population. Finally, the use of frozen spermatozoa does not seem to affect the health of children conceived by AID or IVF/D. The psychosocial development of such infants is not as well known because of the confidentiality in many countries concerning sperm donation. However, the available information on the psychosocial development of these children up to the age of 8-10 years appears to be reassuring. Larger and longer studies are needed to answer such questions, particularly with regard to adulthood. PMID:11212072

Lansac, J; Royere, D

2001-01-01

287

Comparative study of immediately inserted dental implants in sinus lift: 24 months of follow-up  

PubMed Central

Objectives: The primary aim of this study is to evaluate the success rate of immediately inserted dental implants in sinus lift and the secondary aim is to assess the reliability of performing simultaneous surgery for sinus lift, grafting and implant placement in situations of very low residual bone heights (<4 mm) in the posterior maxillae. Materials and Methods: A series of consecutive patients who sought dental implant rehabilitation were included in this study. The sinus lift cases were selected and divided into two groups based on the maxillary alveolar height, ?4 mm of radiographically measurable bone height (Group 1) and < 4 mm of bone height (Group 2). Results: A total of 13 implants were installed in Group 1, whereas 8 implants were installed in Group 2. The success rate for dental implants in the sinus lifts reached 95.2% after a period of 24 months of evaluation, at 100% for Group 1 (bone height ? 4 mm) and 87.5% for Group 2 (bone height with < 4 mm). Besides the differences between the percentages of success, statistical differences were not reached when the groups were compared (Fisher's exact test, P = 0.38). Conclusions: Despite the limitations of this study, including its low number of participants, the results indicate that simultaneous surgery for sinus lifting, grafting and dental implants in posterior maxillae with very low bone heights (<4 mm) can be performed safely, although with lower success rates than found in patients with higher residual bone heights (>4 mm). PMID:24987595

Bortoluzzi, Marcelo Carlos; Manfro, Rafael; Fabris, Vinícius; Cecconello, Rodrigo; Derech, Estevo D’Agostini

2014-01-01

288

Menstrual function among women exposed to polybrominated biphenyls: A follow-up prevalence study  

PubMed Central

Background Alteration in menstrual cycle function is suggested among rhesus monkeys and humans exposed to polybrominated biphenyls (PBBs) and structurally similar polychlorinated biphenyls (PCBs). The feedback system for menstrual cycle function potentially allows multiple pathways for disruption directly through the hypothalamic-pituitary-ovarian axis and indirectly through alternative neuroendocrine axes. Methods The Michigan Female Health Study was conducted during 1997–1998 among women in a cohort exposed to PBBs in 1973. This study included 337 women with self-reported menstrual cycles of 20–35 days (age range: 24–56 years). Current PBB levels were estimated by exponential decay modeling of serum PBB levels collected from 1976–1987 during enrollment in the Michigan PBB cohort. Linear regression models for menstrual cycle length and the logarithm of bleed length used estimated current PBB exposure or enrollment PBB exposure categorized in tertiles, and for the upper decile. All models were adjusted for serum PCB levels, age, body mass index, history of at least 10% weight loss in the past year, physical activity, smoking, education, and household income. Results Higher levels of physical activity were associated with shorter bleed length, and increasing age was associated with shorter cycle length. Although no overall association was found between PBB exposure and menstrual cycle characteristics, a significant interaction between PBB exposures with past year weight loss was found. Longer bleed length and shorter cycle length were associated with higher PBB exposure among women with past year weight loss. Conclusion This study suggests that PBB exposure may impact ovarian function as indicated by menstrual cycle length and bleed length. However, these associations were found among the small number of women with recent weight loss suggesting either a chance finding or that mobilization of PBBs from lipid stores may be important. These results should be replicated with larger numbers of women exposed to similar lipophilic compounds. PMID:16091135

Davis, Stephanie I; Blanck, Heidi Michels; Hertzberg, Vicki S; Tolbert, Paige E; Rubin, Carol; Cameron, Lorraine L; Henderson, Alden K; Marcus, Michele

2005-01-01

289

Prospective study of alcoholism treatment. Eight-year follow-up.  

PubMed

One hundred patients admitted for alcohol withdrawal were followed for eight years. At the eight year mark, 25 percent had achieved stable abstinence of three years' duration or more, and 29 percent had died. Only 26 percent experienced continued serious problems with alcohol. Premorbid social stability and sustained abstinence made independent contributions to good psychosocial outcome at eight years. Premorbid social stability and Alcoholics Anonymous attendance made independent contributions to sustained abstinence. Review of these data and other major longitudinal studies suggests that factors other than professionally organized treatment per se exert substantial effect upon long-term outcome. PMID:6614031

Vaillant, G E; Clark, W; Cyrus, C; Milofsky, E S; Kopp, J; Wulsin, V W; Mogielnicki, N P

1983-09-01

290

Stability of CT scan findings in schizophrenia: results of an 8 year follow-up study.  

PubMed Central

Earlier cross-sectional studies have suggested that CT findings of ventricular enlargement and increased cortical markings in schizophrenic patients are not progressive, but individual patients have rarely been followed prospectively. Fifteen patients with chronic schizophrenia were rescanned on the same model machine after 7 to 9 years of continuous illness and, in seven cases, of continuous hospitalisation. It was not possible to demonstrate significant changes in either ventricular-brain ratio or frontal atrophy scores. These results suggest that the pathologic process responsible for CT changes in schizophrenia is static and is not affected by 8 years of neuroleptic medication and institutionalisation. Images PMID:3346684

Illowsky, B P; Juliano, D M; Bigelow, L B; Weinberger, D R

1988-01-01

291

A follow-up study of neurometabolic alterations in female concussed athletes.  

PubMed

Athletes who sustain a concussion demonstrate a variety of symptoms and neuropsychological alterations that could be brought on by neurometabolic abnormalities. However, no study has yet investigated these aspects in female athletes using magnetic resonance spectroscopy. The present study investigated the neurometabolic and -psychological effects of a concussion in the acute (7-10 days postinjury) and chronic (6 months postinjury) phases after injury. Eleven female concussed athletes and 10 female control athletes were scanned at both time points in a 3T magnetic resonance imaging scanner. Neuropsychological and symptomatic evaluations were completed at each time point. Neuropsychological alterations and a higher severity of symptoms were found in the acute phase in concussed athletes, relative to controls, but showed recovery in the chronic phase. Concussed athletes showed neurometabolic impairment in prefrontal and motor cortices characterized by a pathological increase of glutamine/glutamate and creatine (Cr) only in the chronic phase. Also, a significant decrease in N-acetyl-aspartate/Cr ratio was observed in control athletes at the second time point. Concussed female athletes showed acute cognitive alterations and higher severity of symptoms that do not appear to be underlied by neurometabolic abnormalities, which are only present in the chronic postinjury phase. PMID:24053210

Chamard, Emilie; Henry, Luke; Boulanger, Yvan; Lassonde, Maryse; Théoret, Hugo

2014-02-15

292

Decreasing of residual alveolar ridge height in complete denture wearers. A five year follow up study.  

PubMed

The resorption of the residual alveolar ridges is a chronic and continuous process of bone remodeling. The aim of this study was to analyse the rate of residual ridge resorption at different sites in the both jaws in complete denture wearers, through a five-year period of denture wearing. Residual ridge changes were measured on successive lateral cephalograms at 5 measurement points of the maxilla and the mandible. The first lateral radiograph was obtained at the delivery of complete dentures. The second lateral cephalogram was obtained after five years of denture wearing. Measurements were performed using a calibrated grid. The results of this study showed the existence of a significant alveolar ridge resorption at all five measurement points of the maxilla and the mandible. The observed variables, such as body mass index and the night time denture wearing had no significant influence on the rate of residual alveolar ridge resorption (p > 0.05). The duration of edentulousness had a significant influence on the rate of residual ridge resorption with significantly higher amounts of alveolar bone height decrease in those patients who had lost the last remaining teeth more recently. PMID:20977102

Kovaci?, Ivan; Celebi?, Asja; Zlatari?, Dubravka Knezovi?; Petricevi?, Nikola; Bukovi?, Dino; Bitanga, Petar; Mikeli?, Branimira; Tadin, Antonija; Mehuli?, Ketij; Ognjenovi?, Marina

2010-09-01

293

Primary headaches in preschool age children: clinical study and follow-up in 163 patients.  

PubMed

Although headache frequency is increasing in preschool age children, an extensive evaluation of the clinical features in affected patients has yet to be achieved. This retrospective study examined 243 patients who were separately analysed in two distinct groups according to the age of onset and the age of first clinical evaluation. Group 1 included preschool age children, while Group 2 consisted of pubertal age patients. In all the patients the importance of a positive family history for headache as a risk factor was confirmed. In addition, when compared with Group 2, Group 1 showed greater male gender prevalence and earlier onset of the attacks. Regarding clinical features, in Group 1, compared with Group 2, the attack duration was shorter with lower symptom association such as photo- or phonophobia, nausea and no pain increase during physical activity. In the same group, tension-type headache was the predominant diagnosis, in contrast to the high migraine prevalence of Group 2. This study also showed that the International Headache Society 1988 classification criteria are not fully adequate for juvenile headaches. In fact, the headaches of more than 10% of patients in Group 1 still remained unclassifiable, while those of all the subjects in Group 2 were properly classifiable. PMID:16426271

Battistella, P A; Fiumana, E; Binelli, M; Bertossi, E; Battista, P; Perakis, E; Soriani, S

2006-02-01

294

Review of 1953-2003 ORAU Follow-Up Studies on Science Education Programs: Impacts on Participants' Education and Careers  

SciTech Connect

Through sponsorship of science education programs for undergraduates and graduates, such as research participation programs and fellowships, the Department of Energy (DOE) encouraged the development of adequate numbers of qualified science and engineering (S&E) personnel to meet its current and future research and development (R&D) needs. This retrospective study summarizes impacts of selected programs on these participants. The summary data are from follow-up studies conducted from 1953 through 2003 by Oak Ridge Associated Universities and its predecessor, the Oak Ridge Institute for Nuclear Studies (ORINS).

Oak Ridge Associated Universities

2006-06-01

295

Homocysteine as a Risk Factor for Hypertension: A 2-Year Follow-Up Study  

PubMed Central

Homocysteine (Hcy) is regarded as a risk factor for hypertension, but research on the causal relationship between Hcy and hypertension is limited. In the present study, we prospectively tracked the blood pressure progression of a normotensive population with different Hcy levels over a 2-year period. The incidence of hypertension with increasing Hcy quartiles produced an approximately U-shaped curve, with significance in males. Compared with the third quartile, the risk of hypertension in the first and second quartiles was increased by 1.55 (95% confidence interval [CI] 1.154–2.081) fold and 1.501 (95% CI 1.119–2.013) fold, respectively, with the increase being more significant in males. In conclusion, Hcy is related to hypertension incidence with the results approximating an U-shaped curve. Low Hcy levels might also increase the risk of hypertension. PMID:25310282

Yao, Tao; Li, DongQing; Wang, YanXiu; Li, YuQing; Wu, ShouLing; Cai, Jun

2014-01-01

296

A follow-up study on extracorporeal fixation of condylar fractures using vertical ramus osteotomy  

PubMed Central

Objectives The aim of this study is to report the results of extracorporeal fixation in patients with mandibular condylar fractures and compare them with the clinical results of conservative treatment. Materials and Methods The medical records of 92 patients (73 male [M] : 19 female [F], age 13-69 years, mean 33.1 years) treated for condylar fractures at the Department of Oral and Maxillofacial Surgery in Sun Dental Hospital (Daejeon, Korea) from 2007 to 2012 were reviewed. Patients were divided into three groups: group A (23 patients; M : F=18 : 5, age 21-69 years, mean 32.6 years), treated with extracorporeal fixation; group B (30 patients; M : F=24 : 6, age 16-57 years, mean 21.1 years), treated by conventional open reduction; and group C (39 patients; M : F=31 : 8, age 16-63 years, mean 34.4 years), treated with the conservative method ('closed' reduction). Clinical and radiographic findings were evaluated and analyzed statistically. Results Occurrence of postoperative condylar resorption correlated with certain locations and types of fracture. In this study, patients in group A (treated with extracorporeal fixation) did not demonstrate significant postoperative complications such as malocclusion, mandibular hypomobility, temporomandibular disorder, or complete resorption of condyle fragments. Conclusion In superiorly located mandibular condyle fractures, exact reconstruction of condylar structure with the conventional open reduction technique can be difficult due to the limited surgical and visual fields. In such cases, extracorporeal fixation of the condyle using vertical ramus osteotomy may be a better choice of treatment because it results in anatomically accurate reconstruction and low risk of complications. PMID:24868504

Park, Sung Yong; Im, Jae Hyoung; Yoon, Seong Hoe

2014-01-01

297

Energy and macronutrient intake in adolescent sprint athletes: a follow-up study.  

PubMed

Macronutrient intake, height, weight, and body composition of 60 adolescent sprint athletes were estimated every 6 months over 3 years. Seven-day food records were analysed based on the Belgian and Dutch food databanks. The age of participants at the start of the 3-year study was 14.8 ± 1.6 years for female athletes and 14.7 ± 1.9 years for male athletes. Girls and boys gained height (3.4 ± 4.6 cm and 5.9 ± 6.6 cm respectively) and weight (5.6 ± 3.5 kg and 8.7 ± 5.5 kg respectively), whereas percent body fat remained unchanged in both girls and boys (around 17.0% and 8.5% respectively). Mean protein intake of around 1.5 g · kg?¹ body weight was within recommendations on each occasion for both sexes. Carbohydrate intakes between 5 and 7 g · kg?¹ body weight support a training programme of moderate intensity. Total and saturated fat intakes were high at the start of the study (girls: 31.8 ± 3.5% and 12.2 ± 2.0% of energy intake; boys: 30.3 ± 4.6% and 12.0 ± 1.9% of energy intake) and it appeared to be difficult to achieve and maintain lower intakes. Consistent low fluid intakes around 40 ml · kg?¹ body weight were observed. General non-stringent advice for improvement of the diet resulted in significant favourable changes only for the consumption of wholegrain bread, vegetables, and soft drinks. Dietary habits of adolescent sprint athletes are not always according to guidelines and are relatively stable but repeated advice can induce moderate improvements. PMID:21086211

Aerenhouts, Dirk; Deriemaeker, Peter; Hebbelinck, Marcel; Clarys, Peter

2011-01-01

298

Hygienic and health characteristics of donkey milk during a follow-up study.  

PubMed

For its characteristics, donkey milk has been proposed as an alternative to goat or artificial milk to feed allergic infants. Therefore, it is important to increase our knowledge on health and immunological characteristics of donkey milk. Ten donkeys, bred as companion animals, were enrolled in this study and sampled once a month, for eight months. Milk (10 ml) was collected from each half udder for somatic cell count (SCC), bacteriological analysis and total bacteria count (TBC). The major pathogens were tested for antimicrobial susceptibility, and Staphylococcus aureus isolates were further genotyped by nanoarray analysis. Whey lysozyme and NAGase (NAG) activities were also assessed. Overall, 101 half-udder milk samples were taken. They showed very low values of TBC (<250 cfu/ml) and SCC (<50 000 cells/ml) and a minor prevalence of pathogens: Staph. aureus was isolated only from 5 milk samples (3 animals), Streptococcus equi from 2 samples and Str. equisimilis from a single sample. All the isolates were sensitive to all antibiotic classes used in veterinary medicine. None of the Staph. aureus isolates were shown to harbour genes coding for any enterotoxin, toxic-shock syndrome toxin or antibiotic resistance. Lysozyme levels were always very high (4000-5000 U/ml), while NAG values were mostly low (<50 U/ml), out of the last part of lactation. The results of this study confirmed the low prevalence of intramammary infections in donkey and the absence of food-borne pathogens, suggesting that donkey milk could be a safe food, if the mammary gland is healthy and the animals are milked in proper hygienic conditions. PMID:20883563

Pilla, Rachel; Daprà, Valentina; Zecconi, Alfonso; Piccinini, Renata

2010-11-01

299

Raynaud phenomenon and mortality: 20+ years of follow-up of the Charleston Heart Study cohort  

PubMed Central

Background Raynaud phenomenon (RP) is a temporary vasoconstrictive condition that often manifests itself in the fingers in response to cold or stress. It often co-occurs with certain chronic diseases that impact mortality. Our objective was to determine whether RP has any independent association with survival. Methods From 1987–1989, a total of 830 participants of the Charleston Heart Study cohort completed an in-person RP screening questionnaire. Two definitions of RP were used: a broad definition that included both blanching (pallor) and cyanotic color changes and a narrow definition that included only blanching. All-cause and cardiovascular disease (CVD) mortality were compared between subjects with and without RP using race-specific survival models that adjusted for age, sex, baseline CVD, and 10-year risk of coronary heart disease. Results Using the narrow RP definition, we identified a significant interaction between older age and the presence of RP on all-cause mortality. In the broad RP definition model, the presence of RP was not associated with CVD mortality among blacks; however, among whites, the presence of RP was associated with a 1.6-fold increase in the hazard associated with CVD-related death (hazard ratio: 1.55, 95% confidence interval: 1.10–2.20, P=0.013). Conclusion RP was independently associated with mortality among older adults in our cohort. Among whites, RP was associated with increased CVD-related death. It is possible that RP may be a sign of undiagnosed vascular disease.

Nietert, Paul J; Shaftman, Stephanie R; Silver, Richard M; Wolf, Bethany J; Egan, Brent M; Hunt, Kelly J; Smith, Edwin A

2015-01-01

300

Self-rated health and survival: a 7-year follow-up study of Australian elderly.  

PubMed Central

OBJECTIVES. This study tested the hypothesis, from North American findings, that global self-ratings of health predict survival for older Australians. METHODS. A stratified sample of Australians 60 years of age and older surveyed in 1981 was resurveyed in 1988. Cox proportional hazard general linear models were constructed separately for men and women to predict survival over 7 years. RESULTS. Better self-ratings of health had an incremental association with survival for women, but only men with poor ratings had significantly worse survival than others. After major illnesses, comorbidities, disability, depression, and social support were controlled for, poor ratings of health for both men and women were not significantly different from excellent ratings in predicting survival. Only women's good and fair health ratings remained significant predictors. CONCLUSIONS. People rate their health as poor on the objective basis of illness and disability. Australian findings show gender differences relative to North American results; methodological differences and site and gender variability in health profiles are discussed as reasons for the varying results. PMID:8017532

McCallum, J; Shadbolt, B; Wang, D

1994-01-01

301

Dermoscopic features of actinic keratosis and follow up with dermoscopy: a pilot study.  

PubMed

Actinic keratosis (AK) is a common precursor of sun-related squamous cell carcinoma. AK is difficult to be differentiated from other malignancies with the naked eyes. Dermoscopic features of AK were previously described in some studies, but not extensively investigated. We investigated the dermoscopic features of AK in Asians and assessed dermoscopy as a post-treatment monitoring tool of AK. We retrospectively examined 34 AK lesions which had been diagnosed by histology. The changes of dermoscopic features and histopathological findings were assessed in all these lesions before and after treatment. Before treatment, 18 lesions were pigmented and 16 lesions were non-pigmented AK dermoscopically. The frequent dermoscopic features of AK were keratin/ scales (79.4%), red pseudonetwork (73.5%), targetoid-like appearance (55.9%), rosette sign (38.2%) and absent fissures/ridges, crypts and milia-like cysts. All the lesions had been treated with either photodynamic therapy, cryotherapy or 5% imiquimod cream. After treatment, dermoscopic features of 33 AK lesions were decreased or disappeared, and skin biopsies confirmed that atypical keratinocytes disappeared. One lesion showed accentuated and new dermoscopic features after treatment, and skin biopsy also showed progressing squamous cell carcinoma. In conclusion, scales, red pseudonetwork, targetoid-like appearance and rosette sign were common dermoscopic findings of AK in Asians. In most cases, the treatment response correlated with the changes in dermoscopic features. These findings suggest that dermoscopy is a useful tool to monitor AK. PMID:25032251

Lee, Ji Hyun; Won, Chae Young; Kim, Gyong Moon; Kim, Si Yong

2014-06-01

302

Parent-Reported Executive Functioning in Post-Institutionalized Children: A Follow-Up Study  

PubMed Central

Objective This study compared parent-rated executive functioning (EF) in 6- to 18-year-old children adopted from psychosocially depriving institutions to that in children adopted from severely or “globally” depriving institutions. Individual continuity in EF over two years was examined in children adopted from psychosocially depriving institutions. Method There were 471 children adopted from psychosocially depriving Russian institutions which provided adequate physical resources but failed to provide a consistent set of responsive caregivers. There were 111 children adopted in the early 1990s from globally depriving Romanian institutions which were characterized by physical deprivation as well as profound psychosocial neglect. Adoptive parents completed a background questionnaire and the Behavior Rating Inventory of Executive Function (BRIEF). Results Children adopted from globally depriving institutions had significantly higher levels of EF difficulties than children adopted from psychosocially depriving institutions. For both groups, adoption after 18 months of age was associated with higher levels of EF difficulties. Children adopted from globally depriving institutions had higher levels of EF difficulties than the BRIEF standardization sample at younger ages at adoption. There was moderate to strong continuity in EF difficulties over two years in children adopted from psychosocially depriving institutions. Conclusions These findings suggest that more severe early deprivation may lead to a higher risk of later EF difficulties, which may persist over time. PMID:23413815

Merz, Emily C.; McCall, Robert B.; Groza, Victor

2013-01-01

303

Human-Grey parrot (Psittacus erithacus) reciprocity: a follow-up study.  

PubMed

In a previous study (Péron et al. in Anim Cogn, doi: 10.1007/s10071-012.05640 , 2012), Grey parrots, working in dyads, took turns choosing one of four differently coloured cups with differing outcomes: empty (null, non-rewarding), selfish (keeping reward for oneself), share (sharing a divisible reward), or giving (donating reward to other). When the dyads involved three humans with different specific intentions (selfish, giving, or copying the bird's behaviour), birds' responses only tended towards consistency with human behaviour. Our dominant bird was willing to share a reward with a human who was willing to give up her reward, was selfish with the selfish human, and tended towards sharing with the copycat human; our subordinate bird tended slightly towards increased sharing with the generous human and selfishness with the selfish human, but did not clearly mirror the behaviour of the copycat. We theorized that the birds' inability to understand the copycat condition fully-that they could potentially maximize reward by choosing to share-was a consequence of their viewing the copycat's behaviour as erratic compared with the consistently selfish or giving humans and thus not realizing that they were indeed being mirrored. We suggested that copycat trials subsequently be performed as a separate experiment, without being contrasted with trials in which humans acted consistently, in order to determine if results might have differed. We have now performed that experiment, and shown that at least one Grey parrot--our dominant--responded in a manner suggesting that he deduced the appropriate contingencies. PMID:24474186

Péron, Franck; Thornburg, Luke; Thornberg, Luke; Gross, Brya; Gray, Suzanne; Pepperberg, Irene M

2014-07-01

304

Predictors for health improvement in patients with fibromyalgia: a 2-year follow-up study.  

PubMed

Fibromyalgia (FM) has a high impact on all aspects of health. The effect from interventions is usually small and characterized by uncertainty. Better insight in predictors for improved health is essential. The present study aimed to understand predictors for patient global impression of change and changes in overall health. Data from a longitudinal cohort of recently diagnosed FM patients (n?=?203) were used. Within this cohort, patients were pre-randomized to either a multidisciplinary (n?=?108) or an, aerobic exercise (n?=?47) program, or usual care (n?=?48). Only a limited number of patients started with the programs (n?=?86) or participated fully, i.e., attended >70 % of the scheduled sessions (n?=?68). Patients completed questionnaires covering all components of the International Classification of Functioning, Disability and Health (ICF) bio-psycho-social model of health, which was used as a framework to structure potential predictors. Principal component analysis was used to reduce the number of potential predictors. Regression analyses were used to explore associations with the outcome variables. Principal component analysis yielded five factors representing areas that covered different ICF components and chapters. "Being employed" and "full participation in a program" were independently associated with a better global impression of change. A longer duration of FM-related symptoms and more limitations in physical areas of body functions were independently associated with a worse impression of overall health. Higher levels of perceived limitations in physical and mental activities were associated with "starting to participate in a program" and with "full participation in a program." Recently diagnosed FM patients that report fewer physical limitations may experience more improvement in health if they are at work and have a positive attitude towards participating in an offered health-care intervention. These findings give support to an active rather than to a care-avoiding attitude of health-care workers in their contacts to these patients. PMID:23975362

van Eijk-Hustings, Yvonne; Kroese, Mariëlle; Boonen, Annelies; Bessems-Beks, Monique; Landewé, Robert

2015-01-01

305

New follow-up study of the atmosphere of GJ1214b  

NASA Astrophysics Data System (ADS)

GJ1214b is an extremely interesting 6.55Mearth and 2.6 Earth radii sub-Neptune planet orbiting a M-dwarf host. Its proximity, only 14pc, makes it an excellent target for studies of exoplanetary atmospheres (Charbonneau et al. 2009). Furthermore, the sub-Neptunes/Super Earth-sized planets are only one step between Jupiter-sized and habitable Earth-sized planets with a biosphere. Due to favorable parameters of GJ1214 system, we posses great coverage of many wavelengths in planetary transmission spectra from optical to NIR regions (Miller-Ricci & Fortney 2009). However, the scenarios for the atmospheric compositions are still open. Based on the available measurements, the solar composition (hydrogen rich) atmosphere can be most probably ruled out. That is given by fact that we observe rather a flat spectrum than the absorption features in the hydrogen rich model. Thus, currently more plausible models are atmosphere composed of heavy elements such as water or atmosphere covered by clouds (Bean, Desert, Kabath et al. 2011). Here, we present our spectrophotometric and photometric measurements obtained with SOI and OSIRIS instruments (both SOAR telescope) and SOFI (ESO NTT). We observed 5 transit events of GJ1214b and determined the Rp/Rs ratios for every measured wavelength (Caceres, Kabath, Hoyer et al. 2013). Our photometric measurements at 0.8 micron (Bessel-I) and at 2.14 micron (NIR narrow band) correlate with the flat transmission spectrum, therefore strongly supporting the water or cloudy atmosphere. Our spectrophotometric measurements in the H+K region do not posses the sufficient precision in the Rp/Rs ratios. We conclude that the hydrogen rich model is less probable. However, to be able to decide if the planetary atmosphere is hidden in clouds or if we encountered a water world, we still need more measurements with extremely high accuracy. Here, literally, every new point counts. Finally, we would like to present preliminary results obtained from our 2013 campaign focused at another small exoplanet GJ436b as a demonstration of potential and limitations for ground based transmission spectroscopy.

Kabath, P.; Cáceres, C.; Hoyer, S.; Ivanov, V. D.; Rojo, P.; Girard, J. H.; Kempton, E. M.-R.; Fortney, J. J.; Minniti, D.

2014-03-01

306

Follow-Up Testing  

Cancer.gov

Provides possible follow-up testing, next steps and treatments for women who receive abnormal cervical screening test results, including estrogen cream, colposcopy, endocervical curettage biopsy, punch biopsy, and cone biopsy.

307

Increased mortality in the slim elderly: a 42 years follow-up study in a general population  

Microsoft Academic Search

The Bergen Clinical Blood Pressure Study in Norway was used to examine the relationship between body mass index (BMI (kg\\/m2)) and total mortality in different age segments. Of 6,811 invited subjects, 5,653 (84%) participated in the study (1965–1971)\\u000a and 4,520 (66%) died during 182,798 person-years of follow-up (1965–2007). Mean age at baseline was 47.5 years; range 22–75 years.\\u000a BMI (kg\\/m2) was calculated

Anne K. Gulsvik; Dag S. Thelle; Morten Mowé; Torgeir B. Wyller

2009-01-01

308

Procedural Outcome and One Year Follow up of Patients Undergoing Endovascular Stenting for Coarctation of Aorta: A Single Center Study  

PubMed Central

Introduction: Coarctation of aorta is the fourth most common cardiac lesion requiring intervention. While surgery used to be the only treatment option, endovascular intervention is now considered the first option in simple coarctation lesions. Despite increased popularity, there are currently no FDA approved stents for use in coarctation of aorta and data on the outcome of this procedure is still sparse. Methods: Between October 2004 and June 2010, 33 patients who underwent treatment with Cheatham-Platinum stents for coarctation of aorta were retrospectively studied. All the patients underwent control CT scans at 6 month and echocardiography at 1 year follow-up. Results: There were 17 females and 16 males with a mean age of 26.64 ± 16.30 years (range 2-71 years). The mean stent length and balloon diameter were 3.18 ± 0.56 mm and 15.7 ± 3.12 mm respectively. We achieved an immediate success rate of 96.9% with the only complication of aortic rupture which led to our single mortality in this series. At 6 month follow up no complications were noted in the CT scans. The mean echocardiographic aortic arch gradient at one year follow up was 21.73 ± 11.06 mmHg. Conclusion: This study is one of the few cohorts of patients with stenting for coarctation of aorta in Iranian population which comprised a diverse group of patients from early childhood to elderly. It was demonstrated in this study that stenting for coarctation of aorta is a safe and effective procedure if done carefully and performed in selected patients. PMID:25031828

Ostovan, Mohammad Ali; Kojuri, Javad; Mokhtaryan, Maryam; Razazi, Vida; Zolghadrasli, Abdolali

2014-01-01

309

Increased Risk of Ischemic Stroke in Young Patients with Ankylosing Spondylitis: A Population-Based Longitudinal Follow-Up Study  

PubMed Central

Background Prospective data on the association between ischemic stroke and ankylosing spondylitis (AS) in the young are sparse. The purpose of this population-based, age- and sex-matched longitudinal follow-up study was to investigate the risk of developing ischemic stroke in young patients with AS. Methods A total of 4562 patients aged 18- to 45-year-old with at least two ambulatory visits in 2001 with a principal diagnosis of AS were enrolled in the AS group. The non-AS group consisted of 22810 age- and sex-matched, randomly sampled subjects without AS. The two-year ischemic stroke-free survival rate for each group were calculated using the Kaplan-Meier method. Cox proportional hazards regression analysis was used to estimate the hazard ratio of ischemic stroke after adjusting for demographic and clinical covariates. Results During follow-up, 21 patients in the AS group and 53 in the non-AS group developed ischemic stroke. The ischemic stroke-free survival rate over the 2 year follow-up was lower in the AS group than the non-AS group (p?=?0.0021). The crude hazard ratio of ischemic stroke for the AS group was 1.98 (95% CI, 1.20–3.29; p?=?0.0079) and the adjusted hazard ratio after controlling for demographic and comorbid medical disorders was 1.93 (95% CI, 1.16–3.20; p?=?0.0110). Conclusion Our study showed an increased risk of developing ischemic stroke in young patients with AS. PMID:24714094

Lin, Chia-Wei; Huang, Ya-Ping; Chiu, Yueh-Hsia; Ho, Yu-Tsun; Pan, Shin-Liang

2014-01-01

310

Follow-up of pediatric celiac disease: value of antibodies in predicting mucosal healing, a prospective cohort study  

PubMed Central

Background In diagnosing celiac disease (CD), serological tests are highly valuable. However, their role in following up children with CD after prescription of a gluten-free diet is unclear. This study aimed to compare the performance of antibody tests in predicting small-intestinal mucosal status in diagnosis vs. follow-up of pediatric CD. Methods We conducted a prospective cohort study at a tertiary-care center. 148 children underwent esophohagogastroduodenoscopy with biopsies either for symptoms ± positive CD antibodies (group A; n = 95) or following up CD diagnosed ? 1 year before study enrollment (group B; n = 53). Using biopsy (Marsh ? 2) as the criterion standard, areas under ROC curves (AUCs) and likelihood-ratios were calculated to estimate the performance of antibody tests against tissue transglutaminase (TG2), deamidated gliadin peptide (DGP) and endomysium (EMA). Results AUCs were higher when tests were used for CD diagnosis vs. follow-up: 1 vs. 0.86 (P = 0.100) for TG2-IgA, 0.85 vs. 0.74 (P = 0.421) for TG2-IgG, 0.97 vs. 0.61 (P = 0.004) for DPG-IgA, and 0.99 vs. 0.88 (P = 0.053) for DPG-IgG, respectively. Empirical power was 85% for the DPG-IgA comparison, and on average 33% (range 13–43) for the non-significant comparisons. Among group B children, 88.7% showed mucosal healing (median 2.2 years after primary diagnosis). Only the negative likelihood-ratio of EMA was low enough (0.097) to effectively rule out persistent mucosal injury. However, out of 12 EMA-positive children with mucosal healing, 9 subsequently turned EMA-negative. Conclusions Among the CD antibodies examined, negative EMA most reliably predict mucosal healing. In general, however, antibody tests, especially DPG-IgA, are of limited value in predicting the mucosal status in the early years post-diagnosis but may be sufficient after a longer period of time. PMID:24524430

2014-01-01

311

Brief cognitive-behavioral therapy for weight loss in midlife women: a controlled study with follow-up  

PubMed Central

Objective Cognitive-behavioral therapy (CBT) has proven to be effective in weight reduction. This study explores whether individual, 8-session CBT can promote weight loss in midlife women. Methods Anthropometric (weight, abdominal perimeter, and body mass index calculation), psychological (health-related and sexual quality of life, stress, anxiety, and depression), and behavioral measures (binge eating disorder and restrained, external, and emotional eating) were assessed at baseline (T1), posttreatment (T2), and 4-month follow-up (T3), for a total of 21 women at baseline; the CBT group (n = 11) and the control group (n = 10; waiting list) were compared. Results Statistically significant effects that were dependent on the intervention were observed on weight (F = 4.402; P = 0.035; ?p2 = 0.404; ? = 0.652) and body mass index (F = 3.804; P = 0.050; ?p2 = 0.369; ? = 0.585); furthermore, marginally significant effects were observed on external eating (F = 2.844; P = 0.095; ?p2 = 0.304; ? = 0.461). At follow-up, women in the CBT group presented with lower weight, abdominal perimeter, body mass index, and external eating; higher health-related quality-of-life and restrained eating were also observed in this group. Most differences identified were at a marginally significant level. Moreover, at follow-up, none of the participants of the CBT group met the criteria for binge eating disorder, whereas the number of women with binge eating disorder in the control group remained the same through all three assessments. Conclusion An effective, though small, weight loss was achieved. Changes in quality of life were also observed. Moreover, changes in external eating behavior were successful. PMID:23091402

Pimenta, Filipa; Leal, Isabel; Maroco, João; Ramos, Catarina

2012-01-01

312

Insomnia symptoms and subsequent cardiovascular medication: a register-linked follow-up study among middle-aged employees.  

PubMed

Sleep disturbances have been associated with an increased risk of cardiovascular disease outcomes. The associations of insomnia with hypertension and dyslipidaemia, the main modifiable cardiovascular risk factors, are less studied. We especially lack understanding on the longitudinal effects of insomnia on dyslipidaemia. We aimed to examine the associations of insomnia symptoms with subsequent prescribed medication for hypertension and dyslipidaemia using objective register-based follow-up data. Baseline questionnaire surveys among 40-60-year-old employees of the City of Helsinki, Finland, were conducted in 2000-2002 (n = 6477, response rate 67%, 78% women) and linked to a national register on prescribed reimbursed medication 5-7 years prior to and 5 years after baseline. Associations between the frequency of insomnia symptoms (difficulties in initiating and maintaining sleep, non-restorative sleep) and hypertension and dyslipidaemia medication during the follow-up were analysed using logistic regression analysis (odds ratios with 95% confidence intervals). Analyses were adjusted for pre-baseline medication, sociodemographic and work-related factors, health behaviours, mental health, and diabetes. Frequent insomnia symptoms were reported by 20%. During the 5-year follow-up, 32% had hypertension medication and 15% dyslipidaemia medication. Adjusting for age, gender and pre-baseline medication, frequent insomnia symptoms were associated with hypertension medication (odds ratio 1.57, 95% confidence interval 1.23-2.00) and dyslipidaemia medication (odds ratio 1.59, 95% confidence interval 1.19-2.12). Occasional insomnia symptoms were also associated with cardiovascular medication, though less strongly. Further adjustments had negligible effects. To conclude, insomnia should be taken into account in the prevention and management of cardiovascular disease and related risk factors. PMID:24313664

Haaramo, Peija; Rahkonen, Ossi; Hublin, Christer; Laatikainen, Tiina; Lahelma, Eero; Lallukka, Tea

2014-06-01

313

The Course of Positive Affective and Cognitive States in Borderline Personality Disorder: A 10-year Follow-up Study  

PubMed Central

This study had two aims. The first was to identify and define the course of positive affective and cognitive states present in borderline personality disorder (BPD) and compare them to those of comparison subjects with other personality disorders. The second was to compare the positive affective and cognitive states of borderline patients who recovered from BPD to those who did not. Two hundred ninety patients with BPD and 72 non-borderline axis II subjects (OPD) completed the Positive Affect Scale (PAS), a 50-item self-report measure designed to assess positive states thought to be common among and characteristic of BPD over a 10-year course of prospective follow-up. Affective, cognitive, and mixed PAS items were separately analyzed, based on respective subscores. Borderline patients reported positive affective, cognitive, and mixed states less frequently than OPD subjects. Additionally, affective, and cognitive subscores increased significantly for both groups taken together over 10-years of follow-up though at greater rates among borderline patients. Mixed subscores showed a significant increase over time and at similar rates for both groups. Within the BPD group, recovered patients reported more positive affective, cognitive, and mixed states compared to non-recovered patients. Results also showed a significant increase in affective and cognitive states at similar rates for both groups taken together over 10-years of follow-up. Mixed subscores also showed a significant increase for both groups taken over time, though at greater rates among recovered borderline patients. Taken together, these results suggest a characteristic profile of positive states within borderline patients that is far lower than those reported by axis II comparison subjects. They also suggest that this characteristic profile is predictive of recovery of BPD over time. PMID:23606922

Reed, Lawrence Ian; Fitzmaurice, Garrett; Zanarini, Mary C.

2013-01-01

314

Follow-up study on F-wave in patients with lumbosacral radiculopathy. Comparison between before and after surgery.  

PubMed

The aim of this study is to explore the clinical value of follow-up examinations of F-wave in patients with lumbosacral radiculopathy. Postoperative changes in the initial abnormalities and their relationship with improvement in clinical findings were examined. Results from conventional motor nerve conduction study at knee-ankle segment are also discussed. The subjects were 30 patients with unilateral lumbosacral radiculopathy caused by herniated disc. F-waves were obtained from abductor hallucis and extensor digitorum brevis by supramaximal stimulation to tibial and peroneal nerves, respectively, at the ankle. Minimal latency (Fmin), maximal latency (Fmax), chronodispersion (Fdif) and duration (Fdur) were used as the parameters. No subject had abnormal motor nerve conduction velocity (MCV) throughout the course of this study, and there was no significant difference between preoperative and postoperative levels. Peroneal Fmin, Fmax, Fdif and tibial Fdur all showed significant (p < 0.05 in Wicoxon signed-rank test) improvement after surgery. Moreover, these overall improvements significantly (p < 0.05 in chi 2 test) correlated with recovery in muscle weakness. However, normalization of F-wave was not always associated with full recovery in muscle weakness at that time. These findings suggested that follow-up examination of F-wave was of value for objective assessment after operation. PMID:8803492

Toyokura, M; Ishida, A; Murakami, K

1996-06-01

315

Genetic Susceptibility to Type 2 Diabetes and Obesity: Follow-Up of Findings from Genome-Wide Association Studies  

PubMed Central

Elucidating the underlying genetic variations influencing various complex diseases is one of the major challenges currently facing clinical genetic research. Although these variations are often difficult to uncover, approaches such as genome-wide association studies (GWASs) have been successful at finding statistically significant associations between specific genomic loci and disease susceptibility. GWAS has been especially successful in elucidating genetic variants that influence type 2 diabetes (T2D) and obesity/body mass index (BMI). Specifically, several GWASs have confirmed that a variant in transcription factor 7-like 2 (TCF7L2) confers risk for T2D, while a variant in fat mass and obesity-associated protein (FTO) confers risk for obesity/BMI; indeed both of these signals are considered the most statistically associated loci discovered for these respective traits to date. The discovery of these two key loci in this context has been invaluable for providing novel insight into mechanisms of heritability and disease pathogenesis. As follow-up studies of TCF7L2 and FTO have typically lead the way in how to follow up a GWAS discovery, we outline what has been learned from such investigations and how they have implications for the myriad of other loci that have been subsequently reported in this disease context. PMID:24719615

Basile, Kevin J.; Johnson, Matthew E.; Xia, Qianghua; Grant, Struan F. A.

2014-01-01

316

Cancer mortality following cardiac catheterization: a preliminary follow-up study on 4,891 irradiated children  

SciTech Connect

A retrospective cohort study was conducted on the risk of radiation-induced cancer mortality following cardiac catheterization. The study included 4,891 children with congenital heart disease who were assessed by cardiac catheterization during 1946 to 1968 at The Hospital for Sick Children, Toronto. The cohort was matched against the Ontario cancer death file from 1950 to 1975. The average period of follow-up was 13 years and more than 66,000 person-years have been accrued from the cohort. No deaths from breast cancer or thyroid cancer were identified. Five cancer deaths were observed and compared with 4.8 expected deaths based on Ontario cancer death rates. The five cancer deaths resulted from three leukemias, one Wilms' tumor, and one unspecified nervous system tumor. The preliminary findings did not demonstrate a significant leukemia risk arising from diagnostic cardiac catheterizations. Continued follow-up of this cohort is required to evaluate the risk of breast and thyroid cancers which can occur more than 20 years following radiation exposure.

Spengler, R.F.; Cook, D.H.; Clarke, E.A.; Olley, P.M.; Newman, A.M.

1983-02-01

317

Cancer mortality following cardiac catheterization: a preliminary follow-up study on 4,891 irradiated children  

SciTech Connect

A retrospective cohort study was conducted on the risk of radiation-induced cancer mortality following cardiac catheterization. The study included 4,891 children with congenital heart disease who were assessed by cardiac catheterization during 1946 to 1968 at The Hospital for Sick Children, Toronto. The cohort was matched against the Ontario cancer death file from 1950 to 1975. The average period of follow-up was 13 years and more than 66,000 person-years have been accrued from the cohort. No deaths from breast cancer or thyroid cancer were identified. Five cancer deaths were observed and compared with 4.8 expected deaths based on Ontario cancer death rates. The five cancer deaths resulted from three leukemias, one Wilms tumor, and one unspecified nervous system tumor. The preliminary findings did not demonstrate a significant leukemia risk arising from diagnostic cardiac catheterizations. Continued follow-up of this cohort is required to evaluate the risk of breast and thyroid cancers which can occur more than 20 years following radiation exposure.

Spengler, R.F.; Cook, D.H.; Clarke, E.A.; Olley, P.M.; Newman, A.M.

1983-02-01

318

Acute fatty liver of pregnancy: Over six months follow-up study of twenty-five patients  

PubMed Central

AIM: To evaluate the prognosis of patients with acute fatty liver of pregnancy (AFLP) 6 mo or longer after discharge. METHODS: The records of pregnant patients diagnosed with AFLP at Beijing Ditan Hospital over a 16-year period were reviewed in November 2012. Patients were monitored using abdominal ultrasound, liver and kidney functions, and routine blood examination. RESULTS: A total of 42 patients were diagnosed with AFLP during the study period, and 25 were followed. The mean follow-up duration was 54.5 mo (range: 6.5-181 mo). All patients were in good physical condition, but one patient had gestational diabetes. The renal and liver functions normalized in all patients after recovery, including in those with pre-existing liver or kidney failure. The ultrasound findings were normal in 12 patients, an increasingly coarsened echo-pattern and increased echogenicity of the liver in 10 patients, and mild to moderate fatty liver infiltration in 3 patients. Cirrhosis or liver nodules were not observed in any patient. CONCLUSION: Acute liver failure and acute renal failure in AFLP patients is reversible. Patients do not require any specific long-term follow-up after recovery from AFLP if their liver function tests have normalized and they remain well.

Xiong, Hao-Feng; Liu, Jing-Yuan; Guo, Li-Min; Li, Xing-Wang

2015-01-01

319

Follow-Up Testing  

MedlinePLUS

... North American Society for Pediatric Gastroenterology, Hepatology and Nutrition state that tTG-IgA testing should be used for follow-up care. Interpreting this test result is straightforward—a celiac on the gluten-free diet should have a negative test. The ...

320

Oral contraceptive use and mortality after 36 years of follow-up in the Nurses’ Health Study: prospective cohort study  

PubMed Central

Objective To determine whether use of oral contraceptives is associated with all cause and cause specific mortality. Design Prospective cohort study. Setting Nurses’ Health Study, data collected between 1976 and 2012. Population 121?701 participants were prospectively followed for 36 years; lifetime oral contraceptive use was recorded biennially from 1976 to 1982. Main outcome measures Overall and cause specific mortality, assessed throughout follow-up until 2012. Cox proportional hazards models were used to calculate the relative risks of all cause and cause specific mortality associated with use of oral contraceptives. Results In our population of 121?577 women with information on oral contraceptive use, 63?626 were never users (52%) and 57?951 were ever users (48%). After 3.6 million person years, we recorded 31?286 deaths. No association was observed between ever use of oral contraceptives and all cause mortality. However, violent or accidental deaths were more common among ever users (hazard ratio 1.20, 95% confidence interval 1.04 to 1.37). Longer duration of use was more strongly associated with certain causes of death, including premature mortality due to breast cancer (test for trend P<0.0001) and decreased mortality rates of ovarian cancer (P=0.002). Longer time since last use was also associated with certain outcomes, including a positive association with violent or accidental deaths (P=0.005). Conclusions All cause mortality did not differ significantly between women who had ever used oral contraceptives and never users. Oral contraceptive use was associated with certain causes of death, including increased rates of violent or accidental death and deaths due to breast cancer, whereas deaths due to ovarian cancer were less common among women who used oral contraceptives. These results pertain to earlier oral contraceptive formulations with higher hormone doses rather than the now more commonly used third and fourth generation formulations with lower estrogen doses. PMID:25361731

Charlton, Brittany M; Rich-Edwards, Janet W; Colditz, Graham A; Missmer, Stacey A; Rosner, Bernard A; Hankinson, Susan E; Speizer, Frank E

2014-01-01

321

Haemostatic variables, serum lipid abnormalities and vascular complications in diabetes mellitus: a 5 year follow-up study.  

PubMed

The relationship among blood lipids, haemostatic and fibrinolytic parameters have been evaluated, during a follow-up study, in 27 non-insulin dependent (type II) diabetic patients. Upon recruitment, and in periodical controls, we observed that plasma triglycerides and VLDL levels correlated inversely, and HDL directly, with the fibrinolytic activity of plasma and euglobulin precipitate. Furthermore triglycerides and VLDL correlated directly with Factor VIII antigen (vWFAg). After 5 years in the study, 12 patients (44%) had macroangiopathic complications, and 9 of these subjects showed persistently high levels of triglycerides (above 2.36 mmol/l). These haemostatic and lipid components, however, do not influence the progression of diabetic retinopathy and nephropathy. The alterations of lipid, haemostatic and fibrinolytic parameters and their possible relationships seem to play an important role in the occurrence of diabetic macroangiopathy. PMID:3382760

Gamba, G; Solerte, S B; Grignani, G; Pacchiarini, L; Montani, N; Ferrari, E

1988-06-01

322

Skin cancer in patients with psoriasis treated with coal tar. A 25-year follow-up study  

SciTech Connect

For many years, crude coal tar has been used for the treatment of psoriasis. The possible carcinogenic effect of crude coal tar and ultraviolet (UV) radiation (Goeckerman regimen), considered individually or in combination, has been of some concern to physicians. A 25-year follow-up study was completed on 280 patients with psoriasis who were hospitalized and treated with crude coal tar and UV radiation at the Mayo Clinic, Rochester, Minn, during the years 1950 through 1954. The results of this study suggest that the incidence of skin cancer is not appreciably increased above the expected incidence for the general population when patients are treated with coal tar ointments. It seems that the Goeckerman regimen (topical crude coal tar combined with UV radiation) can be used with minimal risk for skin cancer in the treatment of psoriasis.

Pittelkow, M.R.; Perry, H.O.; Muller, S.A.; Maughan, W.Z.; O'Brien, P.C.

1981-08-01

323

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CLEANING: FOLLOW UP QUESTIONNAIRE (UA-D-22.0)  

EPA Science Inventory

The purpose of this SOP is to define the steps involved in cleaning the electronic data generated from data entry of the Follow Up Questionnaire. It applies to electronic data corresponding to the Follow Up Questionnaire that was scanned and verified by the Data Staff during the...

324

Persistence, clearance and reinfection regarding six high risk human papillomavirus types in Colombian women: a follow-up study  

PubMed Central

Background The design of new healthcare schemes which involve using molecular HPV screening means that both persistence and clearance data regarding the most prevalent types of HR-HPV occurring in cities in Colombia must be ascertained. Methods This study involved 219 HPV positive women in all of whom 6 types of HR-HPV had been molecularly identified and quantified; they were followed-up for 2 years. The Kaplan-Meier survival function was used for calculating the time taken for the clearance of each type of HPV. The role of a group of independent variables concerning the time taken until clearance was evaluated using a Cox proportional-hazards regression model or parametric (log-logistic) methods when necessary. Regarding viral load, the Wilcoxon rank-sum test was used for measuring the difference of medians for viral load for each type, according to the state of infection (cleared or persistent). The Kruskal-Wallis test was used for evaluating the change in the women’s colposcopy findings at the start of follow-up and at the end of it (whether due to clearance or the end of the follow-up period). Results It was found that HPV-18 and HPV-31 types had the lowest probability of becoming cleared (1.76 and 2.75 per 100 patients/month rate, respectively). Women from Colombian cities other than Bogotá had a greater probability of being cleared if they had HPV-16 (HR 2.58: 1.51–4.4 95% CI) or HPV-58 (1.79 time ratio: 1.33-2.39 95% CI) infection. Regarding viral load, HPV-45-infected women having 1?×?106 to 9.99?×?109 viral copies had better clearance compared to those having greater viral loads (1.61 time ratio: 1.01-2.57 95% CI). Lower HPV-31 viral load values were associated with this type’s persistence and changes in colposcopy findings for HPV-16 gave the worst prognosis in women having low absolute load values. Conclusions HPV infection clearance in this study was related to factors such as infection type, viral load and the characteristics of the cities from which the women came. Low viral load values would indicate viral persistence and a worse prognosis regarding a change in colposcopy findings. PMID:25030273

2014-01-01

325

Combined therapy with bevacizumab and photodynamic therapy for myopic choroidal neovascularization: A one-year follow-up controlled study  

PubMed Central

AIM To evaluate the efficacy and safety of a combined treatment for myopic choroidal neovascularization (CNV) using photodynamic therapy (PDT) and intravitreal bevacizumab and to compare it with intravitreal bevacizumab monotherapy. METHODS Thirty-four eyes with angiographic evidence of myopic CNV were randomly divided into two groups: 17 were treated with one intravitreal bevacizumab injection (1.25 mg) and low-fluence-rate PDT within seven days of the injection (Group A). The other 17 received monotherapy with bevacizumab injections (Group B). Clinical evidence of complications, best corrected visual acuity (BCVA) and fluorescein leakage were evaluated. BCVA and optical coherence tomography (OCT) were evaluated monthly. The timepoints follow-up was established at 6 and 12mo. All patients were retreated following a PRN protocol. RESULTS A total of 34 eyes of 34 patients (26 women and 8 men) with a mean age of 62.35 years were included. In Group A (17 eyes) the mean BCVA increased from 0.55±0.13 logMAR before the treatment to 0.40±0.09 logMAR at the 12mo follow-up (P<0.01). In Group B (17 eyes) the mean BCVA increased from 0.60±0.11 logMAR before the treatment to 0.55±0.12 logMAR at the 12mo follow-up (P<0.01). There was no statistically significant difference between the two groups in terms of LogMar visual acuity. In Group A the mean number of combined treatments was 1.8±0.11 per patient; in Group B the mean number of intravitreal bevacizumab injections was 3.1±0.08 per patient. The number of treatments was significantly fewer in Group A (P<0.01). No local or systemic side effects occurred among any of the patients treated in this study. CONCLUSION The combination of anti-angiogenic injections and PDT appears to be a safe and effective option for myopic CNV treatment and allows for a significant reduction of intravitreal injections. PMID:24790881

Saviano, Sandro; Piermarocchi, Rita; Leon, Pia E.; Mangogna, Alessandro; Zanei, Andrea; Cavarzeran Sc, Fabiano; Tognetto, Daniele

2014-01-01

326

Conventional and liquid-based cervicovaginal cytology: a comparison study with clinical and histologic follow-up.  

PubMed

Increased rates of squamous intraepithelial lesion (SIL) diagnosis with liquid-based cervicovaginal cytology (CVC) methods are well documented. This retrospective study compares the ability of the ThinPrep Pap Test (TP) and the conventional Pap smear (CP) to detect biopsy-proven SIL and to exclude nonneoplastic disease. All CVC reports from January 1999 through December 2000 from seven community Family Medicine clinics affiliated with the University of Nebraska were reviewed. For women with at least one CVC diagnosis of epithelial cell abnormality (ECA), follow-up histology, cytology, and clinical data were obtained. Statistical analysis was performed using the chi-square method. SIL was diagnosed in 166 of 3,286 patients by TP (5.1%) and in 169 of 4,872 patients by CP (3.5%) (P < 0.001); 32 of the TP diagnoses (1.0%) and 34 of the CP diagnoses (0.7%) were high-grade SIL (HSIL). Atypical squamous or glandular cells of undetermined significance (ASCUS/AGUS) was the most severe abnormality diagnosed by TP in 218 patients (6.6%) and by CP in 279 patients (5.7%). Follow-up histology data on CVC SIL diagnoses showed evidence of cervical intraepithelial neoplasia in 94 patients screened by TP (2.9%) and in 79 patients screened by CP (1.6%) (P < 0.001); the biopsy diagnoses were CIN 2 or CIN 3 in 34 patients in the TP group (1.0%) and in 28 patients in the CP group (0.6%) (P < 0.025). Follow-up of patients in whom the first ECA CVC diagnosis was ASCUS or AGUS disclosed a positive predictive value for CIN of 22.8% for TP ASCUS/AGUS diagnoses and 11.9% for CP ASCUS/AGUS diagnoses (P < 0.005). In this population, TP was significantly better than CP in detecting biopsy- proven disease and in screening out benign abnormalities. PMID:12203869

Baker, John J

2002-09-01

327

Natural course of care dependency in residents of long-term care facilities: prospective follow-up study  

PubMed Central

Background Insight in the natural course of care dependency of vulnerable older persons in long-term care facilities (LTCF) is essential to organize and optimize individual tailored care. We examined changes in care dependency in LTCF residents over two 6-month periods, explored the possible predictive factors of change and the effect of care dependency on mortality. Methods A prospective follow-up study in 21 Dutch long-term care facilities. 890 LTCF residents, median age 84 (Interquartile range 79–88) years participated. At baseline, 6 and 12 months, care dependency was assessed by the nursing staff with the Care Dependency Scale (CDS), range 15–75 points. Since the median CDS score differed between men and women (47.5 vs. 43.0, P?=?0.013), CDS groups (low, middle and high) were based on gender-specific 33% of CDS scores at baseline and 6 months. Results At baseline, the CDS groups differed in median length of stay on the ward, urine incontinence and dementia (all P?follow-up, 10% improved to a higher CDS group, 65% were in the same, and 25% had deteriorated to a lower CDS group; a similar pattern emerged at 12-month follow-up. Gender, age, urine incontinence, dementia, cancer and baseline care dependency status, predicted an increase in care dependency over time. Conclusion The majority of residents were stable in their care dependency status over two subsequent 6-month periods. Highly care dependent residents showed an increased mortality risk. Awareness of the natural course of care dependency is essential to residents and their formal and informal caregivers when considering therapeutic and end-of-life care options. PMID:24884563

2014-01-01

328

Long-term follow-up of study participants from prophylactic HIV vaccine clinical trials in Africa.  

PubMed

Long-term safety is critical for the development and later use of a vaccine to prevent HIV/AIDS. Likewise, the persistence of vaccine-induced antibodies and their impact on HIV testing must be established. IAVI has sponsored several Phase I and IIA HIV vaccine trials enrolling healthy, HIV-seronegative African volunteers. Plasmid DNA and viral vector based vaccines were tested. No vaccine-related serious adverse events were reported. After completion of vaccine trials conducted between 2001-2007, both vaccine and placebo recipients were offered enrolment into an observational long-term follow-up study (LTFU) to monitor potential late health effects and persistence of immune responses. At scheduled 6-monthly clinic visits, a health questionnaire was administered; clinical events were recorded and graded for severity. Blood was drawn for HIV testing and cellular immune assays. 287 volunteers were enrolled; total follow-up after last vaccination was 1463 person years (median: 5.2 years). Ninety-three (93)% of volunteers reported good health at their last LTFU visit. Infectious diseases and injuries accounted for almost 50% of the 175 reported clinical events, of which over 95% were mild or moderate in severity. There were 30 six pregnancies, six incident HIV infections and 14 volunteers reported cases of social harm. Persistence of immune responses was rare. No safety signal was identified. No potentially vaccine-related medical condition, no immune mediated disease, or malignancy was reported. HIV vaccines studied in these trials had a low potential of induction of persisting HIV antibodies. PMID:24374365

Schmidt, Claudia; Jaoko, Walter; Omosa-Manyonyi, Gloria; Kaleebu, Pontiano; Mpendo, Juliet; Nanvubya, Annet; Karita, Etienne; Bayingana, Roger; Bekker, Linda-Gail; Chomba, Elwyn; Kilembe, William; Nchabeleng, Maphoshane; Nyombayire, Julien; Stevens, Gwynn; Chetty, Paramesh; Lehrman, Jennifer; Cox, Josephine; Allen, Susan; Dally, Len; Smith, Carol; Fast, Patricia E

2014-03-01

329

Benchmark concentrations for methyl mercury obtained from the 9-year follow-up of the Seychelles Child Development Study.  

PubMed

Methyl mercury (MeHg) is highly toxic to the developing nervous system. Human exposure is mainly from fish consumption since small amounts are present in all fish. Findings of developmental neurotoxicity following high-level prenatal exposure to MeHg raised the question of whether children whose mothers consumed fish contaminated with background levels during pregnancy are at an increased risk of impaired neurological function. Benchmark doses determined from studies in New Zealand, and the Faroese and Seychelles Islands indicate that a level of 4-25 parts per million (ppm) measured in maternal hair may carry a risk to the infant. However, there are numerous sources of uncertainty that could affect the derivation of benchmark doses, and it is crucial to continue to investigate the most appropriate derivation of safe consumption levels. Earlier, we published the findings from benchmark analyses applied to the data collected on the Seychelles main cohort at the 66-month follow-up period. Here, we expand on the main cohort analyses by determining the benchmark doses (BMD) of MeHg level in maternal hair based on 643 Seychellois children for whom 26 different neurobehavioral endpoints were measured at 9 years of age. Dose-response models applied to these continuous endpoints incorporated a variety of covariates and included the k-power model, the Weibull model, and the logistic model. The average 95% lower confidence limit of the BMD (BMDL) across all 26 endpoints varied from 20.1 ppm (range=17.2-22.5) for the logistic model to 20.4 ppm (range=17.9-23.0) for the k-power model. These estimates are somewhat lower than those obtained after 66 months of follow-up. The Seychelles Child Development Study continues to provide a firm scientific basis for the derivation of safe levels of MeHg consumption. PMID:16806480

van Wijngaarden, Edwin; Beck, Christopher; Shamlaye, Conrad F; Cernichiari, Elsa; Davidson, Philip W; Myers, Gary J; Clarkson, Thomas W

2006-09-01

330

Rate of progression of CT-quantified emphysema in male current and ex-smokers: a follow-up study  

PubMed Central

Background Little is known about the factors associated with CT-quantified emphysema progression in heavy smokers. The objective of this study was to investigate the effect of length of smoking cessation and clinical / demographical factors on the rate of emphysema progression and FEV1-decline in male heavy smokers. Methods 3,670 male smokers with mean (SD) 40.8 (17.9) packyears underwent chest CT scans and pulmonary function tests at baseline and after 1 and 3 years follow-up. Smoking status (quitted ?5, ?1-<5, <1 years or current smoker) was noted. Rate of progression of emphysema and FEV1-decline after follow-up were assessed by analysis of variance adjusting for age, height, baseline pulmonary function and emphysema severity, packyears, years in study and respiratory symptoms. The quitted ?5 group was used as reference. Results Median (Q1-Q3) emphysema severity,<-950 HU, was 8.8 (5.1 – 14.1) and mean (SD) FEV1 was 3.4 (0.73) L or 98.5 (18.5) % of predicted. The group quitted ‘>5 years’ showed significantly lower rates of progression of emphysema compared to current smokers, 1.07% and 1.12% per year, respectively (p<0.001). Current smokers had a yearly FEV1-decline of 69 ml, while subjects quit smoking >5 years had a yearly decline of 57.5 ml (p<0.001). Conclusion Quit smoking >5 years significantly slows the rate of emphysema progression and lung function decline. Trial registration Registered at http://www.trialregister.nl with trial number ISRCTN63545820. PMID:23688060

2013-01-01

331

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CODING: FOOD DIARY FOLLOW UP (UA-D-10.0)  

EPA Science Inventory

The purpose of this SOP is to define the coding strategy for the Food Diary Follow Up Questionnaire. This questionnaire was developed for use in the Arizona NHEXAS project and the "Border" study. Keywords: data; coding; food diary follow up questionnaire. The National Human Ex...

332

The National Longitudinal Study of the High School Class of 1972 (NLS-72), Fifth Follow-Up (1986) Data File [machine-readable data file].  

ERIC Educational Resources Information Center

This machine-readable data file (MDRF) contains information from the fifth follow-up survey of the National Longitudinal Survey of the High School Class of 1972. The survey was carried out along with the third survey of the High School and Beyond Study. The fifth follow-up data file consists of 12,841 records. The data tape contains information on…

National Center for Education Statistics (ED), Washington, DC.

333

Risedronate prevents persistent bone loss in prostate cancer patients treated with androgen deprivation therapy: results of a 2-year follow-up study  

Microsoft Academic Search

Androgen deprivation therapy (ADT) for prostate cancer (PCa) causes bone loss. Although we reported previously that risedronate significantly recovers bone mineral density (BMD) for up to 12 months, there have been no reports with longer follow-up periods to date. This study extended our earlier series extending the follow-up period to 24 months. Eligible patients had histologically confirmed PCa without lumbar

K Izumi; A Mizokami; K Sugimoto; K Narimoto; Y Kitagawa; E Koh; M Namiki

2011-01-01

334

Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up  

PubMed Central

Objectives: To evaluate in a prospective, randomized study, the efficacy and safety profile of photoselective vaporization of prostate (PVP) using a 80W potassium titanyl phosphate (KTP) laser when compared to standard transurethral resection of prostate (TURP) in patients with lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE). Materials and Methods: Between February 2009 and August 2009, 117 patients satisfying the eligibility criteria underwent surgery [60 PVP{Group A}; 57 TURP{Group B}]. The groups were compared for functional outcome (both subjective and objective parameters), perioperative parameters and complications, with a follow up of one year. P value<0.05 was considered statistically significant. Results: The baseline characteristics of the two groups were comparable. Mean age was 66.68 years and 65.74 years, mean IPSS score was 19.98 and 20.88, mean prostate volume was 44.77 cc and 49.02 cc in Group A and B, respectively. Improvements in IPSS, QOL, prostate volume, Q max and PVRU at 12 months were similar in both groups. PVP patients had longer operating time, lesser perioperative blood loss, shorter catheterization time and a higher dysuria rate when compared to TURP patients. The overall complication rate was similar in the two groups. Conclusions: In patients with LUTS due to BPE, KTP-PVP is an equally efficacious alternative to TURP with durable results at one year follow up with additional benefits of lesser perioperative blood loss, lesser transfusion requirements and a shorter catheterization time. Long term comparative data is awaited to clearly define the role of KTP-PVP in such patients. PMID:23204660

Mohanty, Nayan K.; Vasudeva, Pawan; Kumar, Anup; Prakash, Sanjay; Jain, Manoj; Arora, Rajender P.

2012-01-01

335

Prospective study of the cementless "New Wave" total knee mobile-bearing arthroplasty: 8-year follow-up.  

PubMed

One of the main factors affecting the survival of a total knee arthroplasty (TKA) is the fixation method. The constraints placed on the bone-implant interface of a mobile-bearing TKA must be taken in account during the design and evaluation phases. For more than two decades, calcium phosphate ceramics, particularly hydroxyapatitis, have been used in Europe to accelerate the bone integration of cementless implants. A prospective study of patients continuously recruited by three senior surgeons at three French private hospitals has been carried out. There were no exclusion criteria. Eighty-four (84) cementless mobile-bearing total knee prosthesis of the brand "New Wave" were implanted in 74 patients over a 2-year period (2004-2005). Implant survival at 8 years was 95 % [with a confidence interval of 95 %: 80.2-96.4 %] when revision for any cause was defined as the endpoint. Five implants required surgical revision to exchange all or part of the implant: two for aseptic loosening of tibial component, one for osteolysis, one for persistent flessum (30°) and one for tibial periprosthetic fracture. Completely integrated implants and event-free outcomes were recorded in 91.4 % of the cases at eight-year follow-up. The Hospital for Special Surgery score significantly improved from 56.8/100 points before the surgery to 83.9/100 points at the last follow-up (p < 0.05). Radiologically, only one patient had radiolucent lines around the tibial and femoral components. This cementless total knee prosthesis yielded good medium-term survival. Cementless arthroplasty can generate solid and durable bone fixation in this total weight-bearing implant, and it seems that the hidroxyapathitis surface in this series stimulate the bone integration at the bone-implant interface. PMID:24858380

Normand, Xavier; Pinçon, Jean-Louis; Ragot, Jean-Marie; Verdier, Régis; Aslanian, Thierry

2015-02-01

336

Does ADHD Predict Substance Use Disorders? A 10-year Follow-up Study of Young Adults With ADHD  

PubMed Central

Objective High rates of Substance Use Disorders (SUD) have been found in samples of adolescents and adults with Attention Deficit Hyperactivity Disorder (ADHD). Predictors of SUD among ADHD children who are at risk for the development of SUD remain understudied. The main aims of this study were to identify clinically meaningful characteristics of children that predicted the future development of SUD and to see whether the role of these characteristics varied by sex. Method Subjects were children and adolescents with (N=268; mean age ± SD = 10.9 ± 3.2 years) and without (N=229; mean age 11.9 ± 3.3 years) DSM-III-R ADHD followed prospectively and blindly over a ten-year follow-up period onto young adult years. Subjects were assessed with structured diagnostic interviews for psychopathology and SUDs. Results Over the ten-year follow-up period, ADHD was found to be a significant predictor of any SUD (Hazards Ratio, (95% Confidence Interval) = 1.47 (1.07, 2.02); p=0.01) and cigarette smoking (2.38 (1.61, 3.53); p<0.01). Within ADHD, comorbid conduct disorder (2.74 (1.66, 4.52); p<0.01) and oppositional defiant disorder (2.21 (1.40, 3.51); p<0.01) at baseline were also found to be significant predictors of SUD. We found similar results for cigarette, alcohol, and drug use disorders. There were few meaningful sex interaction effects. We did not find any clinically significant associations for any social or family environment factors nor cognitive functioning factors (all p values > 0.05). Conclusions These results indicate that ADHD is a significant risk factor for the development of SUD and cigarette smoking in both sexes. PMID:21621138

Wilens, Timothy E.; Martelon, MaryKate; Joshi, Gagan; Bateman, Clancey; Fried, Ronna; Petty, Carter; Biederman, Joseph

2011-01-01

337

A 10 year follow up study of patients transplanted for autoimmune hepatitis: histological recurrence precedes clinical and biochemical recurrence  

PubMed Central

Background and aim: Autoimmune hepatitis (AIH) has been reported to recur after orthotopic liver transplantation (OLT) in 10–35% of patients in small series with a short follow up. The aim of the present study was to examine the clinical and histological outcome more than 10 years after OLT for AIH. Patients and methods: Seventeen women with a mean age of 30 (12) years at the time of OLT, selected from among 44 patients transplanted for AIH, were followed for more than 10 years. The criteria for definite AIH, as established by the International Autoimmune Hepatitis Group, were met in every case. Liver biopsies were performed 1, 2, 5, and 10 years after OLT, and when indicated by abnormal liver function tests. Specimens were examined for evidence of recurrent AIH, namely interface hepatitis, lobular activity, portal lymphoplasmocytic infiltration, and fibrosis. Other signs of recurrence included hypertransaminasaemia, serum autoantibodies, and the response to steroid reintroduction or significant steroid dose increments. Results: AIH recurred in 7 (41%) of 17 patients. In four patients histological abnormalities were detected by means of protocol biopsies 1–5 years before the onset of biochemical abnormalities. Two patients developed severe recurrences after 10 and 15 years, respectively, and required treatment with steroids and tacrolimus. In the other three patients histological recurrence was detected 0.6–3 years post-OLT, concomitantly with biochemical abnormalities. Conclusions: AIH recurred in 41% of patients followed for more than 10 years after OLT. As histological signs preceded biochemical abnormalities in four patients (23.5%), regular liver biopsy is warranted after OLT. Detection of isolated histological signs may call for closer follow up and/or a change in immunosuppressive therapy. PMID:12740348

Duclos-Vallée, J-C; Sebagh, M; Rifai, K; Johanet, C; Ballot, E; Guettier, C; Karam, V; Hurtova, M; Feray, C; Reynes, M; Bismuth, H; Samuel, D

2003-01-01

338

Basal low antioxidant capacity correlates with cognitive deficits in early onset psychosis. A 2-year follow-up study.  

PubMed

The objective of the study is to examine the association of baseline total antioxidant status (TAS) and glutathione (GSH) levels with short- and long-term cognitive functioning in patients with early onset first-episode psychosis, comparing affective and non-affective psychoses. We analysed 105 patients with an early onset-first episode psychosis (age 9-17 years) and 97 healthy controls. Blood samples were taken at admission for measurement of TAS and GSH, and cognitive performance was assessed at baseline and at 2years of follow-up. Regression analysis was used to assess the relationship between TAS/GSH levels at baseline and cognitive performance at both time points, controlling for confounders. Baseline TAS and GSH levels were significantly lower in patients than healthy controls. In patients, baseline TAS was positively associated with the global cognition score at baseline (p=0.048) and two years later (p=0.005), while TAS was not associated with cognitive functioning in healthy controls. Further, baseline TAS in patients was specifically associated with the memory domain at baseline and with the memory and attention domains two years later. Stratifying by affective and non-affective psychoses, significant associations were only found between TAS and cognition in the non-affective psychosis group. Baseline GSH levels were not associated with cognitive functioning at either time point in either group. The antioxidant defence capacity in early onset first-episode psychotic patients is directly correlated with global cognition at baseline and at 2years of follow-up, especially in non-affective psychosis. PMID:24768133

Martínez-Cengotitabengoa, Mónica; Micó, Juan Antonio; Arango, Celso; Castro-Fornieles, Josefina; Graell, Montserrat; Payá, Beatriz; Leza, Juan Carlos; Zorrilla, Iñaki; Parellada, Mara; López, M Purificación; Baeza, Inmaculada; Moreno, Carmen; Rapado-Castro, Marta; González-Pinto, Ana

2014-06-01

339

A 4-Year Follow-up Cohort Study of the Respiratory Functions in Toner-handling Workers  

PubMed Central

Background Focusing on the respiratory function for health effect indices, we conducted a cross-sectional study on workers who did and did not handle toner to compare the longitudinal changes. Methods Among 116 individuals who worked for a Japanese business equipment manufacturer and participated in the study, the analysis included 69 male workers who we were able to follow up for 4 years. We categorized the 40 workers engaged in toner-handling work as the exposed group and the 29 workers not engaged in these tasks as the referent group, and compared their respiratory function test results: peak expiratory flow rate (PEFR), vital capacity (VC), predicted vital capacity (%VC), forced expiratory volume in 1 second (FEV1), and forced expiratory volume in 1 second as a percent of forced vital capacity (FEV1%). Results The cross-sectional study of the respiratory function test results at the baseline and at the 5th year showed no statistically significant differences in PEFR, VC, %VC, FEV1, and FEV1% between the exposed and referent workers. Also, respiratory function time-course for 4 years was calculated and compared between the groups. No statistically significant differences were shown. Conclusion Our study does not suggest any toner exposure effects on respiratory function. However, the number of subjects was small in our study; studies of larger populations will be desired in the future. PMID:25516816

Yanagi, Nobuaki; Kitamura, Hiroko; Mizuno, Mitsuhito; Hata, Koichi; Uchiyama, Tetsuro; Kuga, Hiroaki; Matsushita, Tetsuhiro; Kurosaki, Shizuka; Uehara, Masamichi; Ogami, Akira; Higashi, Toshiaki

2014-01-01

340

The EPICure Study: Association between Hemodynamics and Lung Function at 11 Years after Extremely Preterm Birth  

PubMed Central

Objective To investigate the relationship between disturbed lung function and large-artery hemodynamics in school-age children born extremely preterm (EP) (at 25 completed weeks of gestation or less). Study design This was a cross-sectional study of participants from the EPICure study, now aged 11 years (n = 66), and 86 age- and sex-matched term-born classmates. Spirometry parameters (including forced expiratory volume in 1 second), blood pressure, and augmentation index (AIx, a composite of arterial stiffness and global wave reflections) were measured. Results Compared with their classmates, the EP children had significantly impaired lung function, particularly those with neonatal bronchopulmonary dysplasia. Peripheral blood pressure did not differ significantly between the 2 groups, but AIx values were on average 5% higher (95% CI, 2%-8%) in the preterm infants, remaining significant after adjustment for potential confounders. Neonatal bronchopulmonary dysplasia status was not related to AIx. Lung function and maternal smoking were independently associated with AIx; AIx increased by 2.7% per z-score reduction in baseline forced expiratory volume in 1 second and by 4.9% in those whose mothers smoked during pregnancy. Conclusion The independent association between impaired lung function and cardiovascular physiology in early adolescence implies higher cardiovascular risk for children born EP, and suggests that prevention of chronic neonatal lung disease may be a priority in reducing later cardiovascular risk in preterm infants. PMID:22575246

Bolton, Charlotte E.; Stocks, Janet; Hennessy, Enid; Cockcroft, John R.; Fawke, Joseph; Lum, Sooky; McEniery, Carmel M.; Wilkinson, Ian B.; Marlow, Neil

2012-01-01

341

Prenatal exposure to phthalate ester and pubertal development in a birth cohort in central Taiwan: A 12-year follow-up study.  

PubMed

Phthalate esters are widely used plasticizers that are present in many daily used products. Although some of their reproductive effects have been reported, pubertal development effects from prenatal exposure to phthalates awaits further investigations. A population based birth cohort was established (N=437 at baseline) with maternal exposure to phthalates assessed in urine collected at the third trimester of pregnancy in 2001 and 2002. Their 133 children with prenatal phthalates exposure were followed up for the outcomes of pubertal development by sequential physical examinations at eight and 11 years old in 2009 and 2012. Urinary concentrations of major phthalate metabolites (i.e., mono-2-ethylhexyl phthalate [MEHP], mono-(2-ethyl-5-hydroxyhexyl) phthalate [MEHHP], mono-(2-ethyl-5-oxohexyl) phthalate [MEOHP], mono-butyl phthalate [MBP], mono-benzyl phthalate [MBzP], monomethyl phthalate [MMP], and mono-ethyl phthalate [MEP]) were determined using liquid chromatography linked to tandem mass spectrometry. The reproductive development measurements included bone age (for both genders), testicle size (for boys), uterus size, and ovarian volume (for girls). We reported results of 133 children with complete data by applying generalized estimating equations for the repeated continuous outcomes. After controlling for Tanner stage, we detected a significant association between reduced uterus size and increasing phthalate exposure in the 2(nd) tertile relative to the 1st tertile of creatinine-corrected MEHP (B=-0.40; 95% C.I.: -0.73, -0.07, relative to the 1st tertile) and total DEHP (B=-0.39, 95% C.I.:-0.66, -0.01 for the 2nd tertile and B=0.34, 95% C.I.: -0.67, -0.01 for the 3rd tertile, relative to the 1st tertile) with a linear trend among girls. MBzP was also found negatively associated with bone age/chronological age ratio (B=-0.07, 95% CI: -0.13, -0.01 for the 3rd tertile, relative to the 1st tertile) with a linear trend for girls. We found no evidence of an association between phthalate exposure and ovarian volume or testicle size. This analysis suggests phthalate exposure may affect specific pubertal development characteristics in human beings. Further studies with larger sample sizes and longer follow-up period are warranted. PMID:25460653

Su, Pen-Hua; Chang, Chin-Kuo; Lin, Ching-Yi; Chen, Hsiao-Yen; Liao, Pao-Chi; Hsiung, Chao A; Chiang, Hung-Che; Wang, Shu-Li

2015-01-01

342

Mortality among young injection drug users in San Francisco: a 10-year follow-up of the UFO study.  

PubMed

This study examined associations between mortality and demographic and risk characteristics among young injection drug users in San Francisco, California, and compared the mortality rate with that of the population. A total of 644 young (<30 years) injection drug users completed a baseline interview and were enrolled in a prospective cohort study, known as the UFO ("U Find Out") Study, from November 1997 to December 2007. Using the National Death Index, the authors identified 38 deaths over 4,167 person-years of follow-up, yielding a mortality rate of 9.1 (95% confidence interval: 6.6, 12.5) per 1,000 person-years. This mortality rate was 10 times that of the general population. The leading causes of death were overdose (57.9%), self-inflicted injury (13.2%), trauma/accidents (10.5%), and injection drug user-related medical conditions (13.1%). Mortality incidence was significantly higher among those who reported injecting heroin most days in the past month (adjusted hazard ratio = 5.8, 95% confidence interval: 1.4, 24.3). The leading cause of death in this group was overdose, and primary use of heroin was the only significant risk factor for death observed in the study. These findings highlight the continued need for public health interventions that address the risk of overdose in this population in order to reduce premature deaths. PMID:22227793

Evans, Jennifer L; Tsui, Judith I; Hahn, Judith A; Davidson, Peter J; Lum, Paula J; Page, Kimberly

2012-02-15

343

Physical and mental development of children after levonorgestrel emergency contraception exposure: a follow-up prospective cohort study.  

PubMed

Levonorgestrel (LNG), a dedicated emergency contraception (EC) product, has been available over-the-counter in China for more than 14 yr. Although LNG-EC is considered to have no effects on the developing fetus if the contraceptive fails and pregnancy occurs, there have been a few studies specifically examining this issue. The purpose of this study was to compare the physical and mental development of children born after LNG-EC failure with that of a cohort of children born to mothers with no history of exposure to LNG or any teratogenic substances. A group of 195 children who were exposed to LNG-EC during their mothers' conception cycle (study group) were matched to a group of 214 children without exposure to LNG (control group). The physical and mental development of the children were evaluated and compared over a 2-yr period. There were four congenital malformations in the study group and three in the control group (2.1% vs. 1.4%, respectively, P > 0.05). Over the 2-yr follow-up period, there were no statistically significant differences between the two groups with respect to children's weight, height, head circumference, and intelligence scores, and the values of all parameters of both groups were similar to those of the national standards. In summary, LNG-EC has no effect on the physical growth, mental development, or occurrence of birth defects in children born from pregnancies in which EC failed. PMID:24899575

Zhang, Lin; Ye, Weiping; Yu, Wen; Cheng, Linan; Shen, Lixiao; Yang, Zujing

2014-07-01

344

When Do Natural Language Metaphors Influence Reasoning? A Follow-Up Study to Thibodeau and Boroditsky (2013)  

PubMed Central

In this article, we offer a critical view of Thibodeau and Boroditsky who report an effect of metaphorical framing on readers' preference for political measures after exposure to a short text on the increase of crime in a fictitious town: when crime was metaphorically presented as a beast, readers became more enforcement-oriented than when crime was metaphorically framed as a virus. We argue that the design of the study has left room for alternative explanations. We report four experiments comprising a follow-up study, remedying several shortcomings in the original design while collecting more encompassing sets of data. Our experiments include three additions to the original studies: (1) a non-metaphorical control condition, which is contrasted to the two metaphorical framing conditions used by Thibodeau and Boroditsky, (2) text versions that do not have the other, potentially supporting metaphors of the original stimulus texts, (3) a pre-exposure measure of political preference (Experiments 1–2). We do not find a metaphorical framing effect but instead show that there is another process at play across the board which presumably has to do with simple exposure to textual information. Reading about crime increases people's preference for enforcement irrespective of metaphorical frame or metaphorical support of the frame. These findings suggest the existence of boundary conditions under which metaphors can have differential effects on reasoning. Thus, our four experiments provide converging evidence raising questions about when metaphors do and do not influence reasoning. PMID:25490704

Steen, Gerard J.; Reijnierse, W. Gudrun; Burgers, Christian

2014-01-01

345

Bloodstream infection as a predictor for mortality in severe burn patients: an 11-year study.  

PubMed

In this study we collected and analysed data of the severe burn patients at our institution over an 11-year period in order to shed light on the controversial role of bloodstream infection (BSI) as a predictive factor for mortality in this burn population. The factors examined were age, total body surface area, smoke inhalation, presence of BSI, and BSI with resistant bacteria. In total 1081 burn patients were hospitalized from 2001 to 2011, of whom 4% died. We focused here on 158 severe burn patients, 74 of whom developed BSI, and 35 who died. Using univariate analysis, it appeared that the BSI group had a threefold greater chance of mortality compared to the non-BSI group. Patients with a Ryan score 3 had a 100% chance of mortality and those with a score 0 had 0%. Thus, focusing only on Ryan score 1 and score 2 patients, BSI did not contribute to mortality, nor was it shown to contribute to mortality in a multivariate analysis in which the score and BSI were included together. When BSI did occur, it predicted longer hospitalization periods. We conclude that BSI predicts longer length of hospitalization stay but does not contribute to the prediction of mortality beyond that offered by the Ryan score in a severe burn population. PMID:24093600

Egozi, D; Hussein, K; Filson, S; Mashiach, T; Ullmann, Y; Raz-Pasteur, A

2014-10-01

346

School prevention program for eating disorders in Croatia: a controlled study with six months of follow-up.  

PubMed

The main purpose of this pilot study was to evaluate the efficacy of a schoolbased program of eating disorder prevention on a sample of young adolescents in Croatia. The program was designed to reduce dietary restraint and preoccupation with shape and weight. One hundred and thirty-nine students (69 boys and 70 girls; mean age 12.8 years) were evaluated; 75 participated in the program (experimental group) and 64 formed the control group. Outcome measures included eating disorder attitudes, dieting behavior, selfesteem, and knowledge of the topics covered by the program. Outcome measures were evaluated one week before the intervention, one week afterwards, and during a follow-up of 6 months. The program significantly reduced eating disorder attitudes and dieting behavior, and improved knowledge in the female experimental group. A significant and positive effect on eating disorders attitude and knowledge, but not on dietary habits, was noticed in the male experimental group. No significant effects were observed in the control group. The findings of this prevention program give encouraging results and should be evaluated in further studies on larger samples. PMID:17272946

Pokrajac-Bulian, A; Zivci?-Becirevi?, I; Calugi, S; Dalle Grave, R

2006-12-01

347

New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up  

PubMed Central

Purpose In recent years there has been a growing interest in nonsurgical procedures for facial rejuvenation. Hyaluronic acid is currently the most widely used dermal filler for the treatment of facial wrinkles. However, new products with interesting features are being introduced into the market. Cross-linked carboxymethylcellulose is one of these and represents a new alternative for the correction of wrinkles and facial defects. Patients and methods The retrospective, multicenter, open-label study on nasolabial folds reported here was carried out between January 2010 and April 2014 on 350 subjects between 22 and 67 years of age for a 36-month follow-up period in order to consistently and extensively assess the safety and performance of this treatment. Results The study revealed effective and durable correction of nasolabial wrinkles for periods of 9–12 months. Product reapplication over a 36-month period did not lead to an increase in adverse effects, which always remained rare and of little clinical significance, usually consisting of bruising and redness. Conclusion Cross-linked carboxymethyl cellulose has been shown to be a safe and effective alternative to the resorbable products currently on the market. PMID:25609932

Leonardis, Mauro; Palange, Andrea

2015-01-01

348

A 2-year follow-up study of children with motor coordination problems identified at school entry age.  

PubMed

Children attending primary schools in Leeds were tested soon after school entry with the Standardized Motor Test Battery (SMTB), specifically designed for this study and comprising: finger tapping, peg moving, bead threading, standing on one leg, hopping and walking. Norms of motor performance are provided for each test. Seventeen children failed the SMTB and were designated to the clumsy group and then matched for age and sex with a control group of children from the survey. Observations by parents and teachers rated the clumsy children inferior to their controls in writing, sporting ability and clumsiness. The clumsy children and their controls were then followed up for a minimum of 2 years, when educational performance was assessed and motor performance reassessed. The clumsy children were found to have impaired educational attainment, particularly in writing, compared to their controls, and their motor performance although much improved was still very inferior to controls. The findings of this study suggest that the SMTB is a sensitive test for the early identification of clumsy children. PMID:2449984

Roussounis, S H; Gaussen, T H; Stratton, P

1987-01-01

349

Psychological control and morbidity/mortality in breast cancer patients: a 20-year follow-up study.  

PubMed

The purpose of this paper was to examine the longitudinal effects of psychological sense of control and control-related coping strategies on breast cancer outcomes. Utilizing the California Cancer Registry, follow-up data on cancer recurrence and all-cause mortality were obtained for 54 of 58 women originally diagnosed with breast cancer in 1992 to 1994. Relationships between cancer outcomes and psychological control and mood at 4 and 8 months post-diagnosis were examined. Results of the study showed that a greater sense of control at 8 months was associated with less cancer recurrence, while higher desire for control at both 4 and 8 months was associated with greater likelihood of recurrence. Utilization of an accepting mode of control appeared to mitigate the negative effects of desire for control on recurrence. No significant relationships were observed between mood and mortality or recurrence. These findings suggest the potential value of examining psychological control and control-related coping on cancer outcomes in future epidemiological and clinical studies. PMID:23398270

Astin, John A; Shapiro, Johanna; Shapiro, Deane

2013-01-01

350

Nutritional risk and 5-year mortality of older community-dwelling Canadian men: the Manitoba Follow-Up Study.  

PubMed

This study examines nutritional risk and 5-year mortality rates of community-dwelling older Canadian men participating in the Manitoba Follow-Up Study. The surviving cohort (n = 690; mean age = 86.8 years) was mailed a self-administered Nutrition Survey consisting of SCREEN II, a validated nutrition risk screening tool and health-related questions. Five hundred fifty-three completed surveys (80% completion rate) were returned, with 522 (94%) containing complete responses necessary to score nutritional risk, comprising the participants for this analysis. Forty-four percent of the 522 respondents were scored as high risk, 24% at moderate risk, and 32% at low risk. Over five years from 2007 to 2012, 212 (41%) of the men died, with 1-year, 2-year, 3-year, and 4-year survival rates of 92%, 86%, 77%, and 66%, respectively. Men in the lowest 40th percentile of the nutritional risk distribution accounted for half of all deaths. Adjusted for other characteristics, Cox proportional hazard models demonstrated that with each unit decline on the nutritional risk scale there was a 4% greater risk of mortality (hazard ratio = 0.96 [95% CI 0.94,0.98]). Early identification of older men at nutritional risk and timely nutrition interventions are essential in delaying the progression of morbidity and mortality. PMID:24224939

Broeska, Valerie E; Lengyel, Christina O; Tate, Robert B

2013-01-01

351

Outrunning major weight gain: a prospective study of 8,340consistent runners during 7 years of follow-up  

SciTech Connect

Background: Body weight increases with aging. Short-term,longitudinal exercise training studies suggest that increasing exerciseproduces acute weight loss, but it is not clear if the maintenance oflong-term, vigorous exercise attenuates age-related weight gain inproportion to the exercise dose. Methods: Prospective study of 6,119 maleand 2,221 female runners whose running distance changed less than 5 km/wkbetween their baseline and follow-up survey 7 years later. Results: Onaverage, men who ran modest (0-24 km/wk), intermediate (24-48 km/wk) orprolonged distances (>_48 km/wk) all gained weight throughage 64,however, those who ran ?48 km/wk had one-half the average annual weightgain of those who ran<24 km/wk. Age-related weight gain, and itsreduction by running, were both greater in younger than older men. Incontrast, men s gain in waist circumference with age, and its reductionby running, were the same in older and younger men. Women increased theirbody weight and waist and hip circumferences over time, regardless ofage, which was also reduced in proportion to running distance. In bothsexes, running did not attenuate weight gain uniformly, but ratherdisproportionately prevented more extreme increases. Conclusion: Men andwomen who remain vigorously active gain less weight as they age and thereduction is in proportion to the exercise dose.

Williams, Paul T.

2006-01-06

352

Objective outcome evaluation using inertial sensors in subacromial impingement syndrome: a five-year follow-up study.  

PubMed

Shoulder-related dysfunction is the second most common musculoskeletal disorder and is an increasing burden on health-care systems. Commonly used clinical questionnaires suffer from subjectivity, pain dominance and a ceiling effect. Objective functional measurement has been identified as a relevant issue in clinical rehabilitation. Inertia based motion analysis (IMA) is a new generation of objective outcome assessment tool; it can produce objective movement parameters while being fast, cheap and easy to operate. In this prospective study, an inertial sensor comprising a three-dimensional accelerometer and gyroscope is attached at the humerus to measure shoulder movements during two motion tasks in patients with subacromial impingement syndrome at baseline and at five-year after treatment. One hundred healthy subjects served as healthy reference database and 15 patients were measured pre- and post-treatment. IMA was better able to detect improvement in shoulder movements compared to the clinical questionnaires (Disability of Arm, Shoulder and Hand (DASH) and Simple Shoulder Test (SST); p < 0.05) and was hardly correlated with the clinical questionnaires (Pearson R = 0.39). It may therefore add an objective functional dimension to outcome assessment. The fast assessment (t < 5 min) of a simple motion test makes it suitable for routine clinical follow-up. PMID:24622109

Körver, R J P; Senden, R; Heyligers, I C; Grimm, B

2014-04-01

353

Adipogenesis of Sprague Dawely rats mesenchymal stem cells: a morphological, immunophenotyping and gene expression follow-up study  

PubMed Central

Mesenchymal stem cells (MSCs) offer significant promise as a multipotent source for cell-based therapies and could form the basis for the differentiation and cultivation of tissue grafts to replace damaged tissue. However, no gene expression follow up analysis has been undertaken to characterize the in vitro adipogenic differentiated MSCs. The main goal of this study was to focus on MSCs and to analyze their differentiation capacity. To achieve this aim, bone marrow MSCs from sprague dawely rats were isolated, expanded in monolayer culture and characterized with respect to their cluster of differentiation (CD) and ability for adipogenic differentiation capacity. The expression of CD44, CD45, CD29, CD34, and CD90 on bone marrow derived MSCs was characterized using flow cytometry. Adipogenesis was determined by staining with oil-red O and reverse transcription polymerase chain reaction assessments of lipoprotein lipase, leptin, adiponectin and adipocyte genes at different time intervals, after 4, 7, 14, and 21 days. Our results revealed that the pattern of CD marker expression was highly positive significant with CD29, CD44, and CD90 when compared with CD34 and CD45. MSCs showed proliferative potential and were capable of adipogenic differentiation characterized by reddish brown-droplets following staining with oil-red O and expression of molecular bands of genes. These results demonstrate, at the morphological, immunophenotyping and gene expression levels, the multipotency of MSCs and thus highlight their potential therapeutic value for cell-based tissue engineering. PMID:24987544

2014-01-01

354

The longitudinal relation between brain lesion load and atrophy in multiple sclerosis: a 14 year follow up study  

PubMed Central

Background:Studies have suggested that T2 lesion activity is prominent in early relapsing-remitting multiple sclerosis, whereas brain atrophy, while seen early, appears more evident in later progressive disease. The temporal relation between these processes remains unclear. Objective:To explore the association between changing brain lesion loads and subsequent tissue atrophy in multiple sclerosis. Methods:28 subjects with clinically probable or definite multiple sclerosis (mean age 46.0 years; 17 female and 11 male) were followed for 14 years after first onset of symptoms. T2 lesion loads were estimated soon after symptom onset and at around five, 10, and 14 years later. Disease related atrophy was estimated at the 14 year follow up by comparing brain tissue volumes (proportional to total intracranial volumes) determined in the multiple sclerosis group with data from 29 normal control subjects (mean age 36.7 years; 16 female, 13 male) using multiple linear regression analyses to allow for differences in age and sex distributions. Results:Change in lesion load in the first five years was more closely correlated to disease related brain atrophy at 14 years than later changes in lesion load, although the correlation was only moderate (Spearman correlation = -0.528, p = 0.004). Conclusions:From this, it appears that early rather than later focal lesion accumulation relates to subsequent brain atrophy, but factors unconnected directly with lesion formation probably also play a significant role in determining such atrophy. PMID:14617714

Chard, D; Brex, P; Ciccarelli, O; Griffin, C; Parker, G; Dalton, C; Altmann, D; Thompson, A; Miller, D

2003-01-01

355

Initial experience with linear focused shockwave treatment for erectile dysfunction: a 6-month follow-up pilot study.  

PubMed

Low-intensity shockwaves (LISW) are known to produce revascularization and have been in evaluation and in use to treat erectile dysfunction (ED). The present single-arm pilot study is aimed to assess the safety and efficacy of a dedicated shockwave device (Renova) on vasculogenic ED patients. Fifty-eight patients with mild to severe ED were treated by LISW and their erectile function was evaluated by the International Index of Erectile Function-Erectile Function Domain (IIEF-EF), Sexual Encounter Profile and Global Assessment Questions questionnaires, at baseline and at 1, 3 and 6 months post treatment. The average IIEF-EF increased significantly from 14.78 at baseline to 21.93 at 3 months post treatment and stabilized at 22.26 at 6 months post treatment. Out of 58 patients, 47 (81%) had a successful treatment. No adverse events were reported during the treatment and the follow-up duration. In conclusion, it suggests that the performance of LISW could add a new advanced treatment for ED.International Journal of Impotence Research advance online publication, 4 December 2014; doi:10.1038/ijir.2014.41. PMID:25471316

Reisman, Y; Hind, A; Varaneckas, A; Motil, I

2014-12-01

356

Community-Based Training-Detraining Intervention in Older Women: A Five-Year Follow-Up Study.  

PubMed

This five-year follow-up non-randomized controlled study evaluated community-based training and detraining on body composition and functional ability in older women. Forty-two volunteers (64.3±5.1 yrs) were divided into four groups: aerobic training, strength training, combined aerobic and strength, and control. Body composition and physical fitness were measured at baseline, after nine months of training and after three months of detraining every year. After five years of training, body fat decreased, and fat free mass, strength, and chair test performance increased (p < .05) in all training groups. Training-induced favourable adaptations were reversed during detraining but eventually, training groups presented better values than the control group even after detraining. Thus, nine months of annual training, during a five-year period, induced favorable adaptations on body composition, muscular strength and functional ability in elderly women. Three months of detraining, however, changed the favorable adaptations and underlined the need for uninterrupted exercise throughout life. PMID:25415933

Douda, Helen T; Kosmidou, Konstantina V; Smilios, Ilias; Volaklis, Konstantinos A; Tokmakidis, Savvas P

2014-11-21

357

A follow-up study of bone marrow chromosomes and in vitro colony growth in patients with mastocytosis.  

PubMed

Proliferation of mast cells can give rise to many clinical manifestations in patients, and an association with hematological disorders has been pointed out. The study was initiated to determine whether patients with mastocytosis show a clinical progression in relation to bone marrow cell parameters analyzed. During a median follow-up period of 5.5 years, 10 patients with mastocytosis were re-examined with regard to clinical symptoms, urine histamine metabolites (U-MeImAA), bone marrow cells examined with chromosome analyses, and in vitro stem cell growth for CFU-GM. Seven patients showed a clinical progression with increase of either symptoms, bone marrow infiltrates of mast cells or U-MeImAA. One patient with a myeloproliferative bone marrow morphology had a malignant course. Four of the 7 patients showed an increased colony growth, while 3 showed a decreased growth, in the second examination compared with the first examination. One patient had a persistent clone with the chromosome aberration 9p+. A variable pattern was observed in the other patients, in resemblance with findings in chronic myeloproliferative disorders. Our conclusion is that mastocytosis belongs to the myeloproliferative disorders. PMID:7915453

Swolin, B; Rödjer, S; al-Obaidy, A; Jonell, R; Roupe, G

1994-05-01

358

[Use of pulmonary function tests and biomarkers studies to diagnose and follow-up interstitial lung disease in systemic sclerosis.  

PubMed

Interstitial lung disease (ILD) is becoming one of the main causes of death of patients with systemic sclerosis (SSc). The prevalence of ILD associated with SSc (SSc-ILD) varies from 33% to 100% according to diagnostic methods. Clinical features such as dyspnea on exertion, dry cough, and chest pains are not specific and usually late-appearing, implying more specific tests in the diagnostic, prognosis, and follow-up of ILD in patients with SSc. High resolution thoracic CT scanner (HRCT) is more sensitive than chest X-ray in the detection of SSc-ILD. Pulmonary function tests (PFT) are non-invasive and periodically used to assess the impacts of SSc on respiratory function. Diagnostic values of bronchoalveolar lavage and histological examination on lung biopsy are controversial. However, these techniques are essential for studying cellular and molecular mechanisms underlying the pathophysiology of SSc-ILD. Several biomarkers such as surfactant-A (SP-A), -D (SP-D), mucin-like high molecular weight glycoprotein (KL-6), and chemokine CCL-18 have been implicated in SSc-PID. Serum levels of these proteins are correlated with the severity of SSc-ILD, as assessed by HRCT and/or PFT. Finally, alveolar concentration of exhaled nitric oxide can be used to screen SSc patients with high risk of deterioration of respiratory function, in whom immunosuppressant treatment could be useful in preventing the evolution to irreversible lung fibrosis. PMID:25457218

Hua-Huy, T; Rivière, S; Tiev, K P; Dinh-Xuan, A T

2014-12-01

359

Longitudinal course of obsessive-compulsive disorder in patients with anxiety disorders: a 15-year prospective follow-up study  

PubMed Central

Background Although obsessive-compulsive disorder (OCD) is typically described as a chronic condition, relatively little is known about the naturalistic, longitudinal course of the disorder. The purpose of the current study was to examine the probability of OCD remission and recurrence as well as to explore demographic and clinical predictors of remission. Methods This study uses data from the Harvard/Brown Anxiety Disorders Research Program, which is a prospective, naturalistic, longitudinal study of anxiety disorders. Diagnoses were established by means of a clinical interview at study intake. One hundred thirteen Harvard/Brown Anxiety Disorders Research Program participants with OCD were included in the study; all had a history of at least 1 other anxiety disorder. Assessments were conducted at 6-month and/or annual intervals during 15 years of follow-up. Results Survival analyses showed that the probability of OCD remission was .16 at year 1, .25 at year 5, .31 at year 10, and .42 at year 15. For those who remitted from OCD, the probability of recurrence was .07 at year 1, .15 by year 3, and by year 5, it reached .25 and remained at .25 through year 15. In predictors of course, those who were married and those without comorbid major depressive disorder (MDD) were more likely to remit from OCD. By year 15, 51% of those without MDD remitted from OCD compared to only 20% of those with MDD. Conclusions In the short term, OCD appears to have a chronic course with low rates of remission. However, in the long term, a fair number of people recover from the disorder, and, for those who experience remission from OCD, the probability of recurrence is fairly low. PMID:21349511

Marcks, Brook A.; Weisberg, Risa B.; Dyck, Ingrid; Keller, Martin B.

2013-01-01

360

Prospective Study of Psychiatric Follow-up Default and Medication Compliance after Discharge at a Psychiatric Hospital in Nigeria  

Microsoft Academic Search

We report a prospective follow-up of 81 patients recently discharged from the hospital. Their hospital attendance pattern,\\u000a medication compliance, mental state and social functioning were measured. Defaulters were followed up in the community. At\\u000a 3 months, 49.4% had defaulted, while 51.5% were medication noncompliant. Clinical outcome was best for the Non-Defaulter-Medication\\u000a Compliant (ND-MC) group, worst for the Defaulter-Medication Non-Compliant (D-MNC) group.

A. B. Adeponle; A. S. Baduku; M. L. Adelekan; G. T. Suleiman; S. O. Adeyemi

2009-01-01

361

Mortality From Myocardial Infarction After the Death of a Sibling: A Nationwide Follow?up Study From Sweden  

PubMed Central

Background Death of a sibling represents a stressful life event and could be a potential trigger of myocardial infarction (MI). We studied the association between loss of an adult sibling and mortality from MI up to 18 years after bereavement. Methods and Results We conducted a follow?up study for Swedes aged 40 to 69 years between 1981 and 2002, based on register data covering the total population (N=1 617 010). Sibling deaths could be observed from 1981 and on. An increased mortality rate from MI was found among women (1.25 CI 1.02 to 1.54) and men (1.15 CI 1.03 to 1.28) who had experienced death of an adult sibling. An elevated rate some years after bereavement was found among both women (during the fourth to sixth half?years after the death) and men (during the second to sixth half?years after the death), whereas limited support for a short?term elevation in the rate was found (during the first few months since bereavement). External causes of sibling death were associated with increased MI mortality among women (1.54 CI 1.07 to 2.22), whereas nonexternal causes showed associations in men (1.23 CI 1.09 to 1.38). However, further analyses showed that if the sibling also died from MI, associations were primarily found among both women (1.62 CI 1.00 to 2.61) and men (1.98 CI 1.59 to 2.48). Conclusions Our study provided the first large?scale evidence for mortality from MI associated with the death of a sibling at an adult age. The fact that findings suggested associations primarily between concordant causes of death (both died of MI) could indicate genetic resemblance or shared risk factors during childhood. Future studies on bereavement should carefully deal with the possibility of residual confounding. PMID:23537803

Rostila, Mikael; Saarela, Jan; Kawachi, Ichiro

2013-01-01

362

Cost and effectiveness of follow-up examinations in patients with colorectal cancer resected for cure in a French population-based study  

Microsoft Academic Search

The cost of follow-up examinations for patients having undergone potentially curative surgery for colorectal cancer is considerable.\\u000a The aim of this study was to provide a thorough assessment of the cost and effectiveness of the follow-up tests used during\\u000a the 5 years after surgical resection for colorectal cancer and its recurrences. We studied medical and economic data from\\u000a the records

Frédéric Borie; Jean-Pierre Daurés; Bertrand Millat; Brigitte Trétarre

2004-01-01

363

The translucent cadaver: a follow-up study to gauge the efficacy of implementing changes suggested by students.  

PubMed

In a study conducted in 2011, the use of full body digital X-ray images (Lodox(®) Statscan(®)) and drawings were described for surface anatomy education during which suggestions were made by students on how to improve the method. Educational innovations should continuously be adjusted and improved to provide the best possible scenario for student learning. This study, therefore, reports on the efficacy of implementing some of these suggestions. Suggestions incorporated into the follow-up study included: (1) The inclusion of eight strategically placed labeled digital X-ray images to the dissection halls, (2) The placement of both labeled and unlabeled digital X-ray images online, (3) The inclusion of informal oral questions on surface anatomy during dissection, (4) The requirement of students to submit individual drawings in addition to group drawings into their portfolios, and (5) Integrating information on how to recognize anatomical structures on X-rays into gross anatomy lectures given prior to dissection. Students were requested to complete an anonymous questionnaire. The results of the drawings, tests and questionnaires were compared to the results from the 2011 cohort. During 2012, an increased usage of the digital X-rays and an increase in practical test marks in three out of the four modules (statistically significant only in the cardiovascular module) were reported. More students from the 2012 cohort believed the images enhanced their experience of learning surface anatomy and that its use should be continued in future. The suggested changes, therefore, had a positive effect on surface anatomy education. PMID:23533087

Kotzé, Sanet Henriët; Driescher, Natasha Darné; Mole, Calvin Gerald

2013-01-01

364

Follow-Up Study of Former Journalism Students, 1969-1984. Research Report Series Volume IV, No. 4.  

ERIC Educational Resources Information Center

As part of the overall evaluation of the journalism program at William Rainey Harper College (WRHC) in Illinois, a follow-up survey of former students was conducted to determine current activities and perceptions of the program. Questionnaires were mailed to 236 of the 310 students who had, for the most part, passed three or more journalism…

Havlic, Susanne; And Others

365

Optimal follow-up time for evaluatingobjective response to radiotherapy in patients with hepatocellular carcinoma: a retrospective study.  

PubMed

The time to complete or partial (objective) response to radiotherapy in patients with hepatocellular carcinoma (HCC) is variable; thus, the reported frequency of these responses depends on the length of follow-up. However, the optimum follow-up time is unknown. We soughtto determine the optimal follow-up time from the medical records of 25 patients with 39 HCC lesions who received definitive helical tomotherapy at a daily dose of 2 to 4 Gy at 5 fractions per week, for a total dose of 40 to 60 Gy, between January 2008 and January 2013. We determined the time to objective treatment response and local recurrence after radiotherapy and assessed several predictors of delayed treatment response. The median follow-up time was 15.2 months (range, 7.8 to 52.1 months).Among all 39 lesions, objective responses were observed for 36 (92.3%). The median time to objective response was 3.9 months (range, 1.5 to 9.8 months). The objective response rates increased over time from 15.4% at 3 months to 71.8% at 6 months and 87.2% at 9 months. Age60 years old or older and post-radiotherapy ?-fetoprotein concentrations higher than pre-radiotherapy concentrationspredicted delayed treatment response.The objective response rate continued toincrease over 9 months. Therefore, to fully evaluate the treatment response of HCC, we recommend continuous observationfor at least 9 months after radiotherapy. PMID:25418189

Kong, Moonkyoo; Hong, Seong Eon

2014-11-21

366

Primary School Sun Protection Policies and Practices 4 Years after Baseline--A Follow-Up Study  

ERIC Educational Resources Information Center

Before the 2005 launch of the New Zealand SunSmart Schools Accreditation Programme (SSAP), 242 randomly sampled primary schools completed a mail survey about sun protection policies, practices, curriculum and environment. A 2009 follow-up included 189 (78%) and their mean Total Accreditation Score (TAS = total SSAP requirements met, range 0-12),…

Reeder, Anthony I.; Jopson, Janet A.; Gray, Andrew

2012-01-01

367

A Screening Instrument for Autism at 18 Months of Age: A 6Year Follow-up Study  

Microsoft Academic Search

ObjectivesA population of 16,235 children aged 18 months was screened using the Checklist for Autism in Toddlers (CHAT) to identify childhood autism (CA). Two further screening procedures were conducted at age 3 and 5 years. The population was followed up at age 7 years in order to establish the sensitivity, specificity, and positive predictive value of the instrument.

GILLIAN BAIRD; TONY CHARMAN; SIMON BARON-COHEN; ANTONY COX; JOHN SWETTENHAM; SALLY WHEELWRIGHT; AURIOL DREW

2000-01-01

368

Barriers to and Facilitators of Postpartum Follow-Up Care in Women with Recent Gestational Diabetes Mellitus: A Qualitative Study  

PubMed Central

Abstract Objectives Women with a history of gestational diabetes mellitus (GDM) have an increased risk of developing type 2 diabetes (T2DM) but often do not return for follow-up care. We explored barriers to and facilitators of postpartum follow-up care in women with recent GDM. Methods We conducted 22 semistructured interviews, 13 in person and 9 by telephone, that were audiotaped and transcribed. Two investigators independently coded transcripts. We identified categories of themes and subthemes. Atlas.ti qualitative software (Berlin, Germany) was used to assist data analysis and management. Results Mean age was 31.5 years (standard deviation) [SD] 4.5), 63% were nonwhite, mean body mass index (BMI) was 25.9?kg/m2 (SD 6.2), and 82% attended a postpartum visit. We identified four general themes that illustrated barriers and six that illustrated facilitators to postpartum follow-up care. Feelings of emotional stress due to adjusting to a new baby and the fear of receiving a diabetes diagnosis at the visit were identified as key barriers; child care availability and desire for a checkup were among the key facilitators to care. Conclusions Women with recent GDM report multiple barriers and facilitators of postpartum follow-up care. Our results will inform the development of interventions to improve care for these women to reduce subsequent diabetes risk. PMID:21265645

Ennen, Christopher S.; Carrese, Joseph A.; Hill-Briggs, Felicia; Levine, David M.; Nicholson, Wanda K.; Clark, Jeanne M.

2011-01-01

369

Treatment of Adjustment Disorder with Anxiety: A September 11, 2001, Case Study with a 1-Year Follow-Up  

ERIC Educational Resources Information Center

This article describes the application of cognitive behavioral therapy in the treatment of a 20-year-old White male manifesting an adjustment disorder with anxiety, who initially presented on September 11, 2001, following the terrorist attacks. The initial treatment regime lasted 8 weeks. In addition, follow-up sessions at 6, 11, and 12 months…

Powell, Shawn; McCone, Dave

2004-01-01

370

Criterion validity of a competency-based assessment center in medical education – a 4-year follow-up study  

PubMed Central

Introduction Core competencies have progressively gained importance in medical education. In other contexts, especially personnel selection and development, assessment centers (ACs) are used to assess competencies, but there is only a limited number of studies on competency-based ACs in medical education. To the best of our knowledge, the present study provides the first data on the criterion-related validity of a competency-based AC in medical education. Methods We developed an AC tailored to measure core competencies relevant to medical education (social-ethical, communicative, self, and teaching) and tested its validity in n=30 first-year medical students using 3- to 4-year follow-up measures such as (a) objective structured clinical examinations (OSCE) on basic clinical skills (n=26), (b) OSCE on communication skills (n=21), and (c) peer feedback (n=18). The AC contained three elements: interview, group discussion, and role play. Additionally, a self-report questionnaire was provided as a basis for the interview. Results Baseline AC average score and teaching competency correlated moderately with the communication OSCE average score (r=0.41, p=0.03, and r=0.38, p=0.04, respectively). Social-ethical competency in the AC showed a very strong convergent association with the communication OSCE average score (r=0.60, p<0.01). The AC total score also showed a moderate correlation with the overall peer feedback score provided in Year 4 (r=0.38, p=0.06). In addition, communicative competency correlated strongly with the overall peer feedback (r=0.50, p=0.02). We found predominantly low and insignificant correlations between the AC and the OSCE on basic clinical skills (r=?0.33 to 0.30, all p's>0.05). Conclusion The results showed that competency-based ACs can be used at a very early stage of medical training to successfully predict future performance in core competencies. PMID:25219931

Rotthoff, Thomas; Ostapczuk, Martin S.; Kröncke, Klaus D.; Zimmerhofer, Alexander; Decking, Ulrich; Schneider, Matthias; Ritz-Timme, Stefanie

2014-01-01

371

Autonomic cardiovascular responses in acclimatized lowlanders on prolonged stay at high altitude: a longitudinal follow up study.  

PubMed

Acute exposure to hypobaric hypoxia at high altitude is reported to cause sympathetic dominance that may contribute to the pathophysiology of high altitude illnesses. The effect of prolonged stay at high altitude on autonomic functions, however, remains to be explored. Thus, the present study aimed at investigating the effect of high altitude on autonomic neural control of cardiovascular responses by monitoring heart rate variability (HRV) during chronic hypobaric hypoxia. Baseline electrocardiography (ECG) data was acquired from the volunteers at mean sea level (MSL) (<250 m) in Rajasthan. Following induction of the study population to high altitude (4500-4800 m) in Ladakh region, ECG data was acquired from the volunteers after 6 months (ALL 6) and 18 months of induction (ALL 18). Out of 159 volunteers who underwent complete investigation during acquisition of baseline data, we have only included the data of 104 volunteers who constantly stayed at high altitude for 18 months to complete the final follow up after 18 months. HRV parameters, physiological indices and biochemical changes in serum were investigated. Our results show sympathetic hyperactivation along with compromise in parasympathetic activity in ALL 6 and ALL 18 when compared to baseline data. Reduction of sympathetic activity and increased parasympathetic response was however observed in ALL 18 when compared to ALL 6. Our findings suggest that autonomic response is regulated by two distinct mechanisms in the ALL 6 and ALL 18. While the autonomic alterations in the ALL 6 group could be attributed to increased sympathetic activity resulting from increased plasma catecholamine concentration, the sympathetic activity in ALL 18 group is associated with increased concentration of serum coronary risk factors and elevated homocysteine. These findings have important clinical implications in assessment of susceptibility to cardio-vascular risks in acclimatized lowlanders staying for prolonged duration at high altitude. PMID:24404157

Dhar, Priyanka; Sharma, Vijay K; Hota, Kalpana B; Das, Saroj K; Hota, Sunil K; Srivastava, Ravi B; Singh, Shashi B

2014-01-01

372

Using testosterone and cortisol as biomarker to training individualization in elite basketball. A 4-year follow-up study.  

PubMed

The purpose of the present study was to determine the responses of testosterone and cortisol, with special reference to playing positions, playing time and phase of the season. We carried out a follow-up study during four consecutive seasons to investigate the effects of playing time, positional role and phase of the season on anabolic-catabolic biomarkers (plasma total testosterone -TT- and cortisol -C-) on twenty professional male basketball players (27.0 ± 4.2 y; 24.4 ± 1.2 kg/m). First blood samples were collected right after the off-season period and considered as baseline. Samples were taken periodically every 4 to 6 weeks, always after a 24-36h break following the last game played. Statistical procedures were non-parametric mainly. Hormonal status was playing position-dependent, power forwards showed the lowest TT values (med ± IQR; PF: 18.1 ± 4.9; nMol/l) and small forwards the highest ones of C (0.55 ± 0.118 µMol/l). Players who played between 13 to 25-min per game showed the highest values of TT (22.8 ± 6.9 nMol/l) and TT/C (47.1 ± 21.2). March and April showed the most catabolic and/or stressed hormonal state (low TT/C values and high ones of C), and that is necessary to take into account according to playing time (>25-min per game) and specific playing position. Monitoring plasma TT and C is recommended to prevent excessive stress caused by professional basketball season requirements. PMID:25144130

Schelling, X; Calleja-González, J; Torres-Ronda, L; Terrados, N

2014-08-20

373

Multisite quantitative ultrasound for the prediction of fractures over 5 years of follow-up: the Canadian Multicentre Osteoporosis Study.  

PubMed

This study assessed the ability of multisite quantitative ultrasound (mQUS) to predict fracture over a 5-year follow-up. Participants were a subset of the Canadian Multicentre Osteoporosis Study. mQUS-assessed speed of sound (SOS in m/s) at three sites (distal radius, tibia, and phalanx) and extensive questionnaires were completed, after which participants were followed for 5 years and incident fractures recorded. Two survival analyses were completed for each site--a univariate analysis and an adjusted multivariate analysis controlling for age, antiresorptive use, femoral neck bone mineral density, number of diseases, previous fractures, body mass index (BMI), parental history of hip fracture, current smoking, current alcoholic drinks >3 per day, current use of glucocorticoids, and rheumatoid arthritis diagnosis (variables from the FRAX 10-year fracture risk assessment tool). The unit of change for regression analyses was one standard deviation for all measurement sites, specific to site and sex. Separate analyses were completed for all clinical fractures, nonvertebral fractures, and hip fractures by sex. There were 2633 women and 1108 men included, and they experienced 204 incident fractures over 5 years (5.5% fractured). Univariate models revealed statistically significant (p?

Olszynski, Wojciech P; Brown, Jacques P; Adachi, Jonathan D; Hanley, David A; Ioannidis, George; Davison, Kenneth S

2013-09-01

374

Adult neurobehavioral outcome of hyperbilirubinemia in full term neonates—a 30 year prospective follow-up study  

PubMed Central

Background. Neonatal hyperbilirubinemia (HB) may cause severe neurological damage, but serious consequences are effectively controlled by phototherapy and blood exchange transfusion. HB is still a serious health problem in economically compromised parts of the world. The long term outcome has been regarded favorable based on epidemiological data, but has not been confirmed in prospective follow-up studies extending to adulthood. Methods. We studied the long term consequences of HB in a prospective birth cohort of 128 HB cases and 82 controls. The cases are part of a neonatal at-risk cohort (n = 1196) that has been followed up to 30 years of age. HB cases were newborns ? 2500 g birth weight and ? 37 weeks of gestation who had bilirubin concentrations > 340 µmol/l or required blood exchange transfusion. Subjects with HB were divided into subgroups based on the presence (affected HB) or absence (unaffected HB) of diagnosed neurobehavioral disorders in childhood, and compared with healthy controls. Subjects were seen at discharge, 5, 9 and 16 years of life and parent’s and teacher’s assessments were recorded. At 30 years they filled a questionnaire about academic and occupational achievement, life satisfaction, somatic and psychiatric symptoms including a ADHD self-rating score. Cognitive functioning was tested using ITPA, WISC, and reading and writing tests at 9 years of life. Results. Compared to controls, the odds for a child with HB having neurobehavioral symptoms at 9 years was elevated (OR = 4.68). Forty-five per cent of the HB group were affected by cognitive abnormalities in childhood and continued to experience problems in adulthood. This was apparent in academic achievement (p < 0.0001) and the ability to complete secondary (p < 0.0001) and tertiary (p < 0.004) education. Also, the subgroup of affected HB reported persisting cognitive complaints e.g., problems with reading, writing and mathematics. Childhood symptoms of hyperactivity/impulsivity (p < 0.0001) and inattention (p < 0.02) were more common in HB groups, but in adulthood the symptoms were equal. The affected HB had lower scores in parameters reflecting life satisfaction, less controlled drinking, but not increased substance abuse. Discussion. Our results indicate that neonatal HB has negative consequences in adult age. A prospectively collected cohort with strict inclusion criteria enables to control most of the bias factors involved with retrospective data. The control and HB groups were remarkably similar at birth in terms of medical data, and the growth environment of the children, as well as the parents’ social groups, education, size of family, type of housing at birth and at 9 years of age. Our findings bear resemblance to disorders of the fronto-striatal network, and also symptoms of the ADHD spectrum were frequent in the HB group suggesting a link of HB to other neurodevelopmental disorders. PMID:24688870

Launes, Jyrki; Michelsson, Katarina

2014-01-01

375

Cherubism--a case report with long term follow up.  

PubMed

Cherubism is a rare non-neoplastic disease of the bone characterized by bilateral painless enlargement of the jaws giving a cherubic appearance to the patient. It is an autosomal dominant disorder but may occur sporadically. In this paper, we have tried to explain about the clinical, radiological and histopathologic features of cherubism by presenting a case study. A case study of a 7 year old male patient, who first presented with mandibular bilateral swellings to our department in 1998, has been presented. In-depth clinical, radiological and histopathologic examination was done. An extensive long-term follow-up till 11 years was maintained. When presented for the first time, radiological investigation showed characteristic multilocular lytic lesions of the mandible bilaterally. Histopathological examination of the biopsy specimen showed proliferating fibrous connective tissue interspersed by multinucleated giant cells. It was diagnosed as a case nonfamilial cherubism. Follow-up after 5 years showed involvement of the maxilla as well, which was then corrected by surgical methods. Upon follow up 11 years after the first presentation, it was seen that the lesion was regressing by itself and there was improvement in facial contour. The natural course of Cherubism through its progression, stabilization and involution of the disease after puberty, has been highlighted in this case. More, in-depth studies to understand the nature and the pathogenesis of this condition better are required. PMID:22234113

Chavali, Lakshmi V; Bhimalingam, R M Rao; Sudhakar, P V

2011-01-01

376

Q fever in the Netherlands: public perceptions and behavioral responses in three different epidemiological regions: a follow-up study  

PubMed Central

Background Over the past years, Q fever has become a major public health problem in the Netherlands, with a peak of 2,357 human cases in 2009. In the first instance, Q fever was mainly a local problem of one province with a high density of large dairy goat farms, but in 2009 an alarming increase of Q fever cases was observed in adjacent provinces. The aim of this study was to identify trends over time and regional differences in public perceptions and behaviors, as well as predictors of preventive behavior regarding Q fever. Methods One cross-sectional survey (2009) and two follow-up surveys (2010, 2012) were performed. Adults, aged ?18 years, that participated in a representative internet panel were invited (survey 1, n?=?1347; survey 2, n?=?1249; survey 3, n?=?1030). Results Overall, public perceptions and behaviors regarding Q fever were consistent with the trends over time in the numbers of new human Q fever cases in different epidemiological regions and the amount of media attention focused on Q fever in the Netherlands. However, there were remarkably low levels of perceived vulnerability and perceived anxiety, particularly in the region of highest incidence, where three-quarters of the total cases occurred in 2009. Predictors of preventive behavior were being female, older aged, having Q fever themselves or someone in their household, more knowledge, and higher levels of perceived severity, anxiety and (self-) efficacy. Conclusions During future outbreaks of (zoonotic) infectious diseases, it will be important to instil a realistic sense of vulnerability by providing the public with accurate information on the risk of becoming infected. This should be given in addition to information about the severity of the disease, the efficacy of measures, and instructions for minimising infection risk with appropriate, feasible preventative measures. Furthermore, public information should be adapted to regional circumstances. PMID:24645896

2014-01-01

377

A clinical, neurolinguistic, and radiological study of a Chinese follow-up case with primary progressive aphasia.  

PubMed

Primary progressive aphasia (PPA) is a progressive neurodegenerative disorder characterized by the deterioration of language functions. The Han language bears some unique features from the Latin languages; however, the features of PPA in the Han language-speaking population are not well understood. In this study, we performed a 3-year follow-up on a Han language-speaking PPA patient with corresponding changes in magnetic resonance imaging (MRI). During the early stage, linguistic analysis revealed several symptoms including difficulty with auditory comprehension, right-left disorientation, reading disorders, and agraphia, specifically the execution of serial oral instructions. This Chinese PPA patient presented with a reading disorder, but his word comprehension ability remained intact. There are two different possible modalities of incorrect writing in this case. The patient also presented with noun-verb double dissociation. The early-stage MRI showed atrophy of the left frontal lobe, which was most severe in the inferior frontal gyrus. Three years later, the patient was found to have progressive atrophy in the parietal, frontal, and temporal lobes, among which the frontal lobe remained the most severely affected region. The brain imaging of the Chinese-speaking PPA patient showed changes similar to those of a Latin language-speaking PPA patient. The prominent change was asymmetrical atrophy in the frontal and temporal lobes. This is the first report of noun-verb double dissociation existing in a Chinese-language speaking PPA patient. The dissociation may be related to an impaired function of the inferior frontal gyrus, which is likely associated with verb-naming in Chinese-speaking people. Several unique features were observed in this case, including impairment in writing ability. PMID:22827556

Zhou, Jiong; Wang, Jian-An; Jiang, Biao; Qiu, Wen-Juan; Yan, Bin; Wang, Yin-Hua

2013-01-01

378

Auditory and Cognitive Deficits Associated with Acquired Amusia after Stroke: A Magnetoencephalography and Neuropsychological Follow-Up Study  

PubMed Central

Acquired amusia is a common disorder after damage to the middle cerebral artery (MCA) territory. However, its neurocognitive mechanisms, especially the relative contribution of perceptual and cognitive factors, are still unclear. We studied cognitive and auditory processing in the amusic brain by performing neuropsychological testing as well as magnetoencephalography (MEG) measurements of frequency and duration discrimination using magnetic mismatch negativity (MMNm) recordings. Fifty-three patients with a left (n?=?24) or right (n?=?29) hemisphere MCA stroke (MRI verified) were investigated 1 week, 3 months, and 6 months after the stroke. Amusia was evaluated using the Montreal Battery of Evaluation of Amusia (MBEA). We found that amusia caused by right hemisphere damage (RHD), especially to temporal and frontal areas, was more severe than amusia caused by left hemisphere damage (LHD). Furthermore, the severity of amusia was found to correlate with weaker frequency MMNm responses only in amusic RHD patients. Additionally, within the RHD subgroup, the amusic patients who had damage to the auditory cortex (AC) showed worse recovery on the MBEA as well as weaker MMNm responses throughout the 6-month follow-up than the non-amusic patients or the amusic patients without AC damage. Furthermore, the amusic patients both with and without AC damage performed worse than the non-amusic patients on tests of working memory, attention, and cognitive flexibility. These findings suggest domain-general cognitive deficits to be the primary mechanism underlying amusia without AC damage whereas amusia with AC damage is associated with both auditory and cognitive deficits. PMID:21152040

Särkämö, Teppo; Tervaniemi, Mari; Soinila, Seppo; Autti, Taina; Silvennoinen, Heli M.; Laine, Matti; Hietanen, Marja; Pihko, Elina

2010-01-01

379

Intensive Rehabilitation Treatment in Early Parkinson's Disease: A Randomized Pilot Study With a 2-Year Follow-up.  

PubMed

Background. Although physical exercise improves motor aspects of Parkinson's disease (PD), it is not clear whether it may also have a neuroprotective effect. Objective. In this 2-year follow-up study, we determined whether intensive exercise in the early stages of the disease slows down PD progression. Methods. Forty newly diagnosed patients with PD were treated with rasagiline and randomly assigned to 2 groups: MIRT Group (two 28-day multidisciplinary intensive rehabilitation treatments [MIRT], at 1-year interval) and Control Group (only drug). In both groups, Unified Parkinson's Disease Rating Scale Section II (UPDRS II), UPDRS III, 6-minute walking test (6MWT), Timed Up-and-Go test (TUG); PD Disability Scale (PDDS), and l-dopa equivalents were assessed at baseline (T0), 6 months (T1), 1 year (T2), 18 months (T3), and 2 years (T4) later. Results. Over 2 years, UPDRS II, UPDRS III, TUG, and PDDS differentially progressed in the 2 groups: In the MIRT Group, all scores at T4 were better than at T0 (all Ps < .03). No changes were noted in the Control Group. l-dopa equivalent dosages increased significantly only in the Control Group (P = .0015), with a decrease in the percentages of patients in monotherapy (T1 40%; T2, T3, and T4 20%). In the MIRT Group, the percentages of such patients remained higher (T1 and T2 100%; T3 89%; T4 75%). Conclusions. These results suggest that MIRT might slow down the progression of motor decay, it might delay the need for increasing drug treatment, and thus, it might have a neuroprotective effect. PMID:25038064

Frazzitta, Giuseppe; Maestri, Roberto; Bertotti, Gabriella; Riboldazzi, Giulio; Boveri, Natalia; Perini, Michele; Uccellini, Davide; Turla, Marinella; Comi, Cristoforo; Pezzoli, Gianni; Ghilardi, M Felice

2015-02-01

380

Fibroblast Growth Factor 23, Cardiovascular Disease Risk Factors, and Phosphorus Intake in the Health Professionals Follow-up Study  

PubMed Central

Summary Background and objectives Fibroblast growth factor 23 (FGF23) regulates phosphorus and vitamin D metabolism. Elevated FGF23 concentrations are associated with cardiovascular disease events and mortality across a broad range of kidney function, but the predictors of FGF23 concentrations in the general population are unclear. Design, setting, participants, & measurements We examined cross-sectional associations of dietary and nondietary parameters with plasma FGF23 in 1261 participants of the Health Professionals Follow-up Study (mean age 64 ± 9, mean creatinine 0.9 ± 0.2 mg/dl, mean FGF23 64 ± 28 RU/ml). Results In multivariable-adjusted analyses, each 5-year increase in age was associated with 2.1 RU/ml higher FGF23, each 500-mg increase in phosphorus intake was associated with 3.4 RU/ml higher FGF23, and each 0.1-mg/dl increase in creatinine was associated with 3.4 RU/ml higher FGF23. Participants in the highest category of body mass index had 9.5 RU/ml higher FGF23 than those in the lowest, smokers had 17.1 RU/ml higher FGF23 than nonsmokers, and participants with hypertension had 6.0 RU/ml higher FGF23 than those without hypertension. With respect to biochemical parameters, higher parathyroid hormone, phosphate, uric acid, and triglyceride levels all were associated independently with higher FGF23 in models adjusted for age, creatinine, and other factors. In a subset of 748 participants with available data, some inflammatory biomarkers were associated independently with higher FGF23. Conclusions In community-dwelling adults with largely preserved kidney function, established cardiovascular risk factors and higher phosphorus intake were associated with higher FGF23. These results might explain the link between FGF23 and cardiovascular disease. PMID:22034506

Wolf, Myles; Taylor, Eric N.

2011-01-01

381

Autism after Adolescence: Population-based 13- to 22-year Follow-up Study of 120 Individuals with Autism Diagnosed in Childhood  

Microsoft Academic Search

Background: Prospective population-based follow-up study of 120 individuals with autism followed from childhood to adulthood. Methods: Individuals with autism, diagnosed in childhood, were followed prospectively for a period of 13–22 years and re-evaluated at ages 17–40 years. The instruments used at follow-up were the DISCO, WAIS-R, WISC-III, Vineland Adaptive Behavior Scales, psychiatric-medical examination and GAF-scale. A set of criteria was used for

Eva Billstedt; Carina Gillberg; Christopher Gillberg

2005-01-01

382

Myopic Shift and Outdoor Activity among Primary School Children: One-Year Follow-Up Study in Beijing  

PubMed Central

Purpose To assess whether a change in myopia related oculometric parameters of primary school children in Beijing was associated with indoors and outdoors activity. Methods The longitudinal school-based study included school children who were examined in 2011 and who were re-examined in 2012. The children underwent a comprehensive eye examination including ocular biometry by optical low-coherence reflectometry and non-cycloplegic refractometry. Parents and children had a detailed interview including questions on time spent indoors and outdoors. Results Out of 681 students examined at baseline, 643 (94.4%) returned for follow-up examination. Within the one-year period, mean time spent daily outdoors increased by 0.4±0.9 hours, mean axial length by 0.26±0.49 mm, the ratio of axial length divided by anterior corneal curvature (AL/CC) by 0.03±0.06, and myopic refractive error by ?0.06±0.89 diopters. In multivariate analysis, elongation of axial length was significantly associated with less total time spent outdoors (P?=?0.02; standardized coefficient beta ?0.12) and more time spent indoors with studying (P?=?0.007; beta: 0.14) after adjustment for maternal myopia (P?=?0.02; beta: 0.12). An increase in AL/CC was significantly associated with less time spent outdoors (P?=?0.01; beta:?0.12) after adjustment for paternal myopia (P?=?0.003; beta: 0.15) and if region of habitation was excludedors for leisure (P?=?0.006; beta:?0.13), with less total time spent outdoors (P?=?0.04; beta:?0.10), or with more time spent i. An increase in myopic refractive error, after adjustment for age, was significantly associated with less time spent outdo ndoors with studying (P?=?0.005; beta: 0.13). Conclusions A change in oculometric parameters indicating an increase in myopia was significantly associated with less time spent outdoors and more time spent indoors in school children in Greater Beijing within a study period of one year. Our study provides additional information on the potentially helpful role of outdoors activity in the prevention of myopia. Public health care measures such as school agendas may potentially take it into account. PMID:24086484

Guo, Yin; Liu, Li Juan; Xu, Liang; Tang, Ping; Lv, Yan Yun; Feng, Yi; Meng, Meng; Jonas, Jost B.

2013-01-01

383

Outcome of a scheme for specialist orthodontic care, a follow-up study in 31-year-olds.  

PubMed

Changes in the occlusion after orthodontic treatment have in several studies been analyzed by the use of the PAR Index developed by Shaw & Richmond. The use of the PAR Index has been shown by O'Brien & Shaw to be a reliable and reproducible method to evaluate orthodontic treatment results. The purpose of the study was to examine the long-range orthodontic treatment outcome by following a group of patients into adulthood to the age of 31 years. For the study 115 individuals from a previous randomized study were invited for follow-up examination at age 31 years. Seventy-two individuals, 32 males (44.4%) and 40 females (55.6%) of the original sample attended for clinical examination. Study casts were obtained and questionnaires addressing the patient's awareness and opinion of the treatment were distributed. In addition twenty-four subjects responded by returning filled-in questionnaires. The mean change in wPAR scores from start to retention represents a mean relative improvement in occlusion of 78.7%. The mean wPar score improvement from age 19 to 31 years was 11.9%. The relative mean wPar score change dropped to 53.5% at age 31 years. The differences in wPAR recordings between the recorded stages were all statistically significant. The treatment outcome as expressed by mean wPAR scores at age 31 years was significantly better among individuals treated with extractions compared to those treated without extractions. The mean wPAR scores of the individuals with retainers at age 31 years were significantly lower when compared to the mean score for those without retainers (unpaired t-test, p = 0.020). This clearly indicates the benefit of long-term retention. The changes in the concern scores from 19 to 31 years of age were small. At age 31 years only 8 of the 96 respondents (8.3%) expressed concern about the treatment outcome. PMID:21591599

Lagerström, Lennart; Fornell, Ann-Charlott; Stenvik, Arild

2011-01-01

384

Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: a prospective, multi-center, follow-up study  

PubMed Central

Introduction Primary Sjögren’s syndrome (pSS) is an autoimmune disorder affecting exocrine glands; however, a subgroup of pSS patients experience systemic extra-glandular involvement leading to a worsening of disease prognosis. Current therapeutic options are mainly empiric and often translated by other autoimmune diseases. In the last few years growing evidence suggests that B-cell depletion by rituximab (RTX) is effective also in pSS. Patients with early active disease appear to be those who could benefit the most from RTX. The aim of this study was to investigate the efficacy and safety of RTX in comparison to disease modifying anti-rheumatic drugs (DMARDs) in early active pSS patients. Methods Forty-one patients with early pSS and active disease (EULAR Sjogren’s syndrome disease activity index, ESSDAI???6) were enrolled in the study. Patients were treated with either RTX or DMARDs in two different Rheumatology centers and followed up for 120 weeks. Clinical assessment was performed by ESSDAI every 12 weeks up to week 120 and by self-reported global disease activity pain, sicca symptoms and fatigue on visual analogic scales, unstimulated saliva flow and Schirmer’s I test at week 12, 24, 48, 72, 96, and 120. Laboratory assessment was performed every 12 weeks to week 120. Two labial minor salivary gland (MSG) biopsies were obtained from all patients at the time of inclusion in the study and at week 120. Results Our study demonstrated that RTX treatment results in a faster and more pronounced decrease of ESSDAI and other clinical parameters compared to DMARDs treatment. No adverse events were reported in the two groups. We also observed that RTX is able to reduce glandular infiltrate, interfere with B/T compartmentalization and consequently with the formation of ectopic lymphoid structures and germinal center-like structures in pSS-MSGs. Conclusions To our knowledge, this is the first study performed in a large cohort of early active pSS patients for a period of 120 weeks. We showed that RTX is a safe and effective agent to be employed in pSS patients with systemic, extra-glandular involvement. Furthermore, our data on pSS-MSGs provide additional biological basis to employ RTX in this disease. PMID:24286296

2013-01-01

385

Two-year follow up study of stress-related disorders among immigrants to Israel from the Chernobyl area.  

PubMed Central

We report on findings from a 2-year follow-up study of immigrants originating from exposed areas around the site of the 1986 Chernobyl accident matched with comparison subjects emigrating from other republics in the Confederation of Independent States. In the initial study of 708 immigrants, the samples were matched by age, gender, and year of immigration. We assessed two exposure groups--high and low--by estimating levels of ground cesium contamination from the International Atomic Energy Agency maps. We reinterviewed 520 immigrants from the first wave of data collection (a reinterview rate of 73%), 87 from high-exposure areas, 217 from low-exposure areas, and 216 comparison subjects. This study examined the prevalence of symptoms of posttraumatic stress disorders (PTSD), depression, somatization, anxiety, and physical effects (high blood pressure, acute symptoms, and chronic illness). The results obtained in the first wave conducted 8 years after the accident showed that psychological symptoms were significantly higher in exposed respondents than in the comparison group. During the second wave (10 years after the accident) we observed a decline in the prevalence of PTSD and related distress except for somatization, which remained at the same level. An association between exposure and high blood pressure was observed in the first wave of data, but was not still significant in the second wave of data collection. The proportion of those who reported three or more chronic health problems was 48.3% among the high-exposure group, 49.3% in the low-exposure group, and 30.6% in the comparison group (p = 0.0003). The most commonly reported problems were heart disease. problems with vision or hearing, migraine headaches, problems with the lymphatic system, and arthritis. Based on the results, it was concluded that the Chernobyl accident was a powerful stressor, having a strong impact on both mental and physical health. Since all respondents were engaged in the process of acculturation and accommodation to a new country after emigration, it is encouraging that this study shows that levels of psychological distress are waning as the new immigrants are absorbed into Israeli society. However, there still remains some independent effect on health associated with the experience of the Chernobyl accident. PMID:9467080

Cwikel, J; Abdelgani, A; Goldsmith, J R; Quastel, M; Yevelson, I I

1997-01-01

386

Prospective study of psychiatric follow-up default and medication compliance after discharge at a psychiatric hospital in Nigeria.  

PubMed

We report a prospective follow-up of 81 patients recently discharged from the hospital. Their hospital attendance pattern, medication compliance, mental state and social functioning were measured. Defaulters were followed up in the community. At 3 months, 49.4% had defaulted, while 51.5% were medication noncompliant. Clinical outcome was best for the Non-Defaulter-Medication Compliant (ND-MC) group, worst for the Defaulter-Medication Non-Compliant (D-MNC) group. Reasons for default include feeling well, financial difficulty, medication side effects and stigma. Medication non-compliant patients were more likely to reside more than 20 km away from hospital. There is an urgent need to provide community psychiatric services to improve patients' access to services and medication compliance. PMID:18633705

Adeponle, A B; Baduku, A S; Adelekan, M L; Suleiman, G T; Adeyemi, S O

2009-02-01

387

Implementing a nationwide criteria-based emergency medical dispatch system: A register-based follow-up study  

PubMed Central

Background A criteria-based nationwide Emergency Medical Dispatch (EMD) system was recently implemented in Denmark. We described the system and studied its ability to triage patients according to the severity of their condition by analysing hospital admission and case-fatality risks. Methods This was a register-based follow-up study of all 1-1-2 calls in a 6-month period that were triaged according to the Danish Index – the new criteria-based dispatch protocol. Danish Index data were linked with hospital and vital status data from national registries. Confidence intervals (95%) for proportions with binomial data were computed using exact methods. To test for trend the Wald test was used. Results Information on level of emergency according to the Danish Index rating was available for 67,135 patients who received ambulance service. Emergency level A (urgent cases) accounted for 51.4% (n?=?34,489) of patients, emergency level B for 46.3% (n?=?31,116), emergency level C for 2.1% (n?=?1,391) and emergency level D for 0.2% (n?=?139). For emergency level A, the median time from call receipt to ambulance dispatch was 2 min 1 s, and the median time to arrival was 6 min 11 s. Data concerning admission and case fatality was available for 55,270 patients. The hospital admission risk for emergency level A patients was 64.4% (95% CI?=?63.8-64.9). There was a significant trend (p?studies are needed to determine the degree of over- and undertriage and prognostic factors. PMID:23835246

2013-01-01

388

Total hip replacements done without cement after acetabular fractures: A 4- to 8-year follow-up study  

Microsoft Academic Search

Twenty-one patients (21 hips) underwent cementless total hip replacement surgeries for previous acetabular fractures. The mean age at the time of hip replacement was 52 years (range, 23–78 years). The mean follow-up was 65 months (range, 48–104 months). One hip required revision of the stem secondary to a periprosthetic femur fracture from a fall at 3 months after surgery. Good

Michael H. Huo; Brian D. Solberg; Laurine E. Zatorski; Kristaps J. Keggi

1999-01-01

389

Training and Certification for Early Childhood Special Education Personnel: A Six-Year Follow-up Study  

Microsoft Academic Search

A six-year follow-up survey of state, district and U.S. territory certification offices was conducted to determine current requirements for early childhood special education personnel. In addition, the status of known training programs was assessed. All 50 states, the District of Columbia, American Samoa, Guam, and Puerto Rico responded. Twenty respondents (20%) reported a separate early childhood special education certification\\/endorsement, 19

Stephen W Stile; Sandra M. Abernathy; Timothy J. Pettibone; William J. Wachtel

1984-01-01

390

Does plasma cholesterol concentration predict mortality from coronary heart disease in elderly people? 18 year follow up in Whitehall study  

Microsoft Academic Search

OBJECTIVE--To explore the extent to which the relation between plasma cholesterol concentration and risk of death from coronary heart disease in men persists into old age. DESIGN--18 year follow up of male Whitehall civil servants. Plasma cholesterol concentrations and other risk factors were determined at first examination in 1967-9 when they were aged 40-69. Death of men up to 31

M J Shipley; S J Pocock; M G Marmot

1991-01-01

391

Clinical conditions of long-term cure in childhood-onset epilepsy: a 45-year follow-up study.  

PubMed

Clinical conditions of long-term cure in childhood-onset epilepsy, defined as sustained remission off antiepileptic drug (AED) treatment, are not well known. To address that clinically important question, we determined clinical factors predictive of long-term seizure cure in a population-based cohort of 133 patients followed up since their first seizure before the age of 16 years. At the end of the 45-year follow-up (mean=39.8, median=44, range=11-47), 81 (61%) of the 133 patients had entered at least 5-year remission off AEDs, meeting our definition of cure. The 81 patients were seizure-free off AEDs for a mean of 34.4 (median=38, range=6-46) years and 59 (73%) of the 81 patients following the first standard medication until the end of follow-up (mean=36.5, median=39, range=14-46 years). Four independent factors were found to be associated with cure compared with having seizures while on AEDs: seizure frequency less than weekly during the first 12 months of AED treatment (p=0.002), pretreatment seizure frequency less than weekly (p=0.002), higher IQ (>70; p=0.021), and idiopathic or cryptogenic vs. symptomatic etiology (p=0.042). Patients with seizure frequency of less than once a week during early treatment and idiopathic etiology had a ninefold chance to of being cured since the onset of the first adequate antiepileptic therapy until the end of follow-up compared with patients who a symptomatic etiology had at least weekly seizures while on AEDs (RR=8.7, 95% CI=2.0-37.0; p<0.001). In conclusion, IQ, etiology, and seizure frequencies both in the first year of AED treatment and prior to medication appear to be clinical predictors of cure in childhood-onset epilepsy. PMID:24975821

Sillanpää, Matti; Saarinen, Maiju; Schmidt, Dieter

2014-08-01

392

Statin Use and Cognitive Function: Population-Based Observational Study with Long-Term Follow-Up  

PubMed Central

We aimed to evaluate the association between statin use and cognitive function. Cognitive function was measured with the Ruff Figural Fluency Test (RFFT; worst score, 0; best score, 175 points) and the Visual Association Test (VAT; low performance, 0–10; high performance, 11–12 points) in an observational study that included 4,095 community-dwelling participants aged 35–82 years. Data on statin use were obtained from a computerized pharmacy database. Analysis were done for the total cohort and subsamples matched on cardiovascular risk (N?=?1232) or propensity score for statin use (N?=?3609). We found that a total of 904 participants (10%) used a statin. Statin users were older than non-users: mean age (SD) 61 (10) vs. 52 (11) years (p<0.001). The median duration of statin use was 3.8 (interquartile range, 1.6–4.5) years. Unadjusted, statin users had worse cognitive performance than non-users. The mean RFFT score (SD) in statin users and non-users was 58 (23) and 72 (26) points, respectively (p<0.001). VAT performance was high in 261 (29%) statin users and 1351 (43%) non-users (p<0.001). However, multiple regression analysis did not show a significant association of RFFT score with statin use (B, ?0.82; 95%CI, ?2.77 to 1.14; p?=?0.41) nor with statin solubility, statin dose or duration of statin use. Statin users with high doses or long-term use had similar cognitive performance as non-users. This was found in persons with low as well as high cardiovascular risk, and in younger as well as older subjects. Also, the mean RFFT score per quintile of propensity score for statin use was comparable for statin users and non-users. Similar results were found for the VAT score as outcome measure. In conclusion, statin use was not associated with cognitive function. This was independent of statin dose or duration of statin use. PMID:25541708

Joosten, Hanneke; Visser, Sipke T.; van Eersel, Marlise E.; Gansevoort, Ron T.; Bilo, Henk J. G.; Slaets, Joris P.; Izaks, Gerbrand J.

2014-01-01

393

Initial impact and cost of a nationwide population screening campaign for diabetes in Brazil: A follow up study  

PubMed Central

Background In 2001 Brazilian citizens aged 40 or older were invited to participate in a nationwide population screening program for diabetes. Capillary glucose screening tests and procedures for diagnostic confirmation were offered through the national healthcare system, diagnostic priority being given according to the severity of screening results. The objective of this study is to evaluate the initial impact of the program. Methods Positive testing was defined by a fasting capillary glucose ? 100 mg/dL or casual glucose ? 140 mg/dL. All test results were tabulated locally and aggregate data by gender and clinical categories were sent to the Ministry of Health. To analyze individual characteristics of screening tests performed, a stratified random sample of 90,106 tests was drawn. To describe the actions taken for positive screenees, a random sub-sample of 4,906 positive screenees was actively followed up through home interviews. Main outcome measures considered were the number of diabetes cases diagnosed and cost per case detected and incorporated into healthcare. Results Of 22,069,905 screening tests performed, we estimate that 3,417,106 (95% CI 3.1 – 3.7 million) were positive and that 346,168 (290,454 – 401,852) new cases were diagnosed (10.1% of positives), 319,157 (92.2%) of these being incorporated into healthcare. The number of screening tests needed to detect one case of diabetes was 64. As many cases of untreated but previously known diabetes were also linked to healthcare providers during the Campaign, the estimated number needed screen to incorporate one case into the healthcare system was 58. Total screening and diagnostic costs were US$ 26.19 million, the cost per diabetes case diagnosed being US$ 76. Results were especially sensitive to proportion of individuals returning for diagnostic confirmation. Conclusion This nationwide population-based screening program, conducted through primary healthcare services, demonstrates the feasibility, within the context of an organized national healthcare system, of screening campaigns for chronic diseases. Although overall costs were significant, cost per new case diagnosed was lower than previously reported. However, cost-effectiveness analysis based on more clinically significant outcomes needs to be conducted before this screening approach can be recommended in other settings. PMID:18808662

Toscano, Cristiana M; Duncan, Bruce B; Mengue, Sotero S; Polanczyk, Carísi Anne; Nucci, Luciana B; Costa e Forti, Adriana; Fonseca, Cláudio D; Schmidt, Maria Inês

2008-01-01

394

Extended follow-up and spatial analysis of the American Cancer Society study linking particulate air pollution and mortality.  

PubMed

We conducted an extended follow-up and spatial analysis of the American Cancer Society (ACS) Cancer Prevention Study II (CPS-II) cohort in order to further examine associations between long-term exposure to particulate air pollution and mortality in large U.S. cities. The current study sought to clarify outstanding scientific issues that arose from our earlier HEI-sponsored Reanalysis of the original ACS study data (the Particle Epidemiology Reanalysis Project). Specifically, we examined (1) how ecologic covariates at the community and neighborhood levels might confound and modify the air pollution-mortality association; (2) how spatial autocorrelation and multiple levels of data (e.g., individual and neighborhood) can be taken into account within the random effects Cox model; (3) how using land-use regression to refine measurements of air pollution exposure to the within-city (or intra-urban) scale might affect the size and significance of health effects in the Los Angeles and New York City regions; and (4) what exposure time windows may be most critical to the air pollution-mortality association. The 18 years of follow-up (extended from 7 years in the original study [Pope et al. 1995]) included vital status data for the CPS-II cohort (approximately 1.2 million participants) with multiple cause-of-death codes through December 31, 2000 and more recent exposure data from air pollution monitoring sites for the metropolitan areas. In the Nationwide Analysis, the influence of ecologic covariate data (such as education attainment, housing characteristics, and level of income; data obtained from the 1980 U.S. Census; see Ecologic Covariates sidebar on page 14) on the air pollution-mortality association were examined at the Zip Code area (ZCA) scale, the metropolitan statistical area (MSA) scale, and by the difference between each ZCA value and the MSA value (DIFF). In contrast to previous analyses that did not directly include ecologic covariates at the ZCA scale, risk estimates increased when ecologic covariates were included at all scales. The ecologic covariates exerted their greatest effect on mortality from ischemic heart disease (IHD), which was also the health outcome most strongly related with exposure to PM2.5 (particles 2.5 microm or smaller in aerodynamic diameter), sulfate (SO4(2-)), and sulfur dioxide (SO2), and the only outcome significantly associated with exposure to nitrogen dioxide (NO2). When ecologic covariates were simultaneously included at both the MSA and DIFF levels, the hazard ratio (HR) for mortality from IHD associated with PM2.5 exposure (average concentration for 1999-2000) increased by 7.5% and that associated with SO4(2-) exposure (average concentration for 1990) increased by 12.8%. The two covariates found to exert the greatest confounding influence on the PM2.5-mortality association were the percentage of the population with a grade 12 education and the median household income. Also in the Nationwide Analysis, complex spatial patterns in the CPS-II data were explored with an extended random effects Cox model (see Glossary of Statistical Terms at end of report) that is capable of clustering up to two geographic levels of data. Using this model tended to increase the HR estimate for exposure to air pollution and also to inflate the uncertainty in the estimates. Including ecologic covariates decreased the variance of the results at both the MSA and ZCA scales; the largest decrease was in residual variation based on models in which the MSA and DIFF levels of data were included together, which suggests that partitioning the ecologic covariates into between-MSA and within-MSA values more completely captures the sources of variation in the relationship between air pollution, ecologic covariates, and mortality. Intra-Urban Analyses were conducted for the New York City and Los Angeles regions. The results of the Los Angeles spatial analysis, where we found high exposure contrasts within the Los Angeles region, showed that air pollution-mortality risks were nearly 3 times greater than those reported fro

Krewski, Daniel; Jerrett, Michael; Burnett, Richard T; Ma, Renjun; Hughes, Edward; Shi, Yuanli; Turner, Michelle C; Pope, C Arden; Thurston, George; Calle, Eugenia E; Thun, Michael J; Beckerman, Bernie; DeLuca, Pat; Finkelstein, Norm; Ito, Kaz; Moore, D K; Newbold, K Bruce; Ramsay, Tim; Ross, Zev; Shin, Hwashin; Tempalski, Barbara

2009-05-01

395

Glycosylated hemoglobin as a screening test for hyperglycemia in antipsychotic-treated patients: a follow-up study  

PubMed Central

Purpose To assess the point prevalence of undetected prediabetes (preDM) and diabetes mellitus (DM) in patients treated with antipsychotics and to compare metabolic parameters between patients with normoglycemia (NG), preDM, and DM. Furthermore, conversion rates for preDM and DM were determined in a 1-year follow-up. Patients and methods In a naturalistic cohort of 169 patients, fasting glucose (FG) and hemoglobin A1c (HbA1c) criteria were applied at baseline and at follow-up after 1 year. A distinction was made between baseline patients diagnosed according to FG (B-FG) and those diagnosed according to HbA1c (B-HbA1c). Conversion rates in the 1-year follow-up were compared between B-FG and B-HbA1c. Results At baseline, preDM and DM were present in 39% and 8%, respectively. As compared to patients with NG, metabolic syndrome was significantly more prevalent in patients with preDM (62% vs 31%). Although the majority of patients were identified by the FG criterion, HbA1c contributed significantly, especially to the number of patients diagnosed with preDM (32%). Regarding the patients with preDM, conversion rates to NG were much higher in the B-FG group than in the B-HbA1c group (72% vs 18%). In patients diagnosed with DM, conversion rates were found for B-FG only. Conclusion PreDM and DM are highly prevalent in psychiatric patients treated with antipsychotic drugs. HbA1c was shown to be a more stable parameter in identifying psychiatric patients with (an increased risk for) DM, and it should therefore be included in future screening instruments. PMID:25653547

Steylen, Pauline MJ; van der Heijden, Frank MMA; Hoogendijk, Witte JG; Verhoeven, Willem MA

2015-01-01

396

Semiautomatic segmentation and follow-up of multicomponent low-grade tumors in longitudinal brain MRI studies  

SciTech Connect

Purpose: Tracking the progression of low grade tumors (LGTs) is a challenging task, due to their slow growth rate and associated complex internal tumor components, such as heterogeneous enhancement, hemorrhage, and cysts. In this paper, the authors show a semiautomatic method to reliably track the volume of LGTs and the evolution of their internal components in longitudinal MRI scans. Methods: The authors' method utilizes a spatiotemporal evolution modeling of the tumor and its internal components. Tumor components gray level parameters are estimated from the follow-up scan itself, obviating temporal normalization of gray levels. The tumor delineation procedure effectively incorporates internal classification of the baseline scan in the time-series as prior data to segment and classify a series of follow-up scans. The authors applied their method to 40 MRI scans of ten patients, acquired at two different institutions. Two types of LGTs were included: Optic pathway gliomas and thalamic astrocytomas. For each scan, a “gold standard” was obtained manually by experienced radiologists. The method is evaluated versus the gold standard with three measures: gross total volume error, total surface distance, and reliability of tracking tumor components evolution. Results: Compared to the gold standard the authors' method exhibits a mean Dice similarity volumetric measure of 86.58% and a mean surface distance error of 0.25 mm. In terms of its reliability in tracking the evolution of the internal components, the method exhibits strong positive correlation with the gold standard. Conclusions: The authors' method provides accurate and repeatable delineation of the tumor and its internal components, which is essential for therapy assessment of LGTs. Reliable tracking of internal tumor components over time is novel and potentially will be useful to streamline and improve follow-up of brain tumors, with indolent growth and behavior.

Weizman, Lior, E-mail: weizmanl@gmail.com [School of Engineering and Computer Science, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel)] [School of Engineering and Computer Science, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel); Sira, Liat Ben [Department of Radiology, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv 64239 (Israel)] [Department of Radiology, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv 64239 (Israel); Joskowicz, Leo [School of Engineering and Computer Science and The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem 91904 (Israel)] [School of Engineering and Computer Science and The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem 91904 (Israel); Rubin, Daniel L.; Yeom, Kristen W. [Department of Radiology, Stanford University, Stanford, California 94305 (United States)] [Department of Radiology, Stanford University, Stanford, California 94305 (United States); Constantini, Shlomi; Shofty, Ben [Tel Aviv Medical Center, Dana Children's Hospital, Tel Aviv University, Tel Aviv 64239 (Israel)] [Tel Aviv Medical Center, Dana Children's Hospital, Tel Aviv University, Tel Aviv 64239 (Israel); Bashat, Dafna Ben [Tel Aviv Medical Center, Functional Brain Center, Tel Aviv University, Tel Aviv 64239 (Israel)] [Tel Aviv Medical Center, Functional Brain Center, Tel Aviv University, Tel Aviv 64239 (Israel)

2014-05-15

397

Social class inequalities in health among occupational cohorts from Finland, Britain and Japan: A follow up study.  

PubMed

We examined whether relative occupational social class inequalities in physical health functioning widen, narrow or remain stable among white collar employees from three affluent countries. Health functioning was assessed twice in occupational cohorts from Britain (1997-1999 and 2003-2004), Finland (2000-2002 and 2007) and Japan (1998-1999 and 2003). Widening inequalities were seen for British and Finnish men, whereas inequalities among British and Finnish women remained relatively stable. Japanese women showed reverse inequalities at follow up, but no health inequalities were seen among Japanese men. Health behaviours and social relations explained 4-37% of the magnitude in health inequalities, but not their widening. PMID:25545770

Lahelma, Eero; Pietiläinen, Olli; Rahkonen, Ossi; Kivimäki, Mika; Martikainen, Pekka; Ferrie, Jane; Marmot, Michael; Shipley, Martin; Sekine, Michikazu; Tatsuse, Takashi; Lallukka, Tea

2015-01-01

398

Natural course of bone marrow oedema on magnetic resonance imaging of the sacroiliac joints in patients with early inflammatory back pain: a 2-year follow-up study.  

PubMed

Objectives: To describe the distribution and evolution over time of bone marrow oedema (BME) on magnetic resonance imaging of the sacroiliac joint (MRI-SIJ) in patients with recent-onset inflammatory back pain (IBP) suspected for axial spondyloarthritis (axSpA). Method: A 2-year follow-up study with annual MRI-SIJ was conducted in patients with IBP of duration ? 2 years. Each SIJ was divided into quadrants and MRI scores were analysed on a per-patient and per-SIJ quadrant basis. The presence of BME in each SIJ quadrant was recorded. Fulfilment of the Assessment of SpondyloArthritis international Society (ASAS) criteria for axSpA was assessed at baseline and at follow-up. Results: At baseline, 68 patients (38% male; mean age 34.9 ± 10.3 years) were included. BME was visible at baseline in 24 (35%) patients, all fulfilling the ASAS axSpA criteria. Twenty-three of these 24 patients had a follow-up MRI. Not taking into account the baseline MRI, three (13%) of these 23 patients would no longer fulfil the ASAS criteria during follow-up because of subsiding BME. Forty-four (65%) patients had a negative baseline MRI, of whom 39 had a follow-up MRI available. New BME at follow-up meant that three (8%) of these 39 patients now fulfilled the ASAS criteria. At follow-up, baseline BME lesions subsided completely in 47% of SIJ quadrants (range 33-71%) whereas new BME lesions were detected in 8% of SIJ quadrants (range 2-11%). Conclusions: BME shows a fluctuating course in patients with early IBP suspected for axSpA. This may have an impact on diagnosis and the overall performance of the ASAS axSpA criteria. PMID:25222204

van Onna, M; van Tubergen, A; Jurik, Ag; van der Heijde, D; Landewé, R

2014-09-15

399

5-year follow-up study of children with low-to-moderate lead absorption: electrophysiological evaluation  

SciTech Connect

Forty-nine children aged 6 to 12 years were evaluated for residual effects of lead exposure using psychometric, electrophysiological, and medical tests 5 years after initial assessment. The original range of blood lead (PbB) levels was 6-59 (anti x = 28) g/dl; the current range was 6-30 (anti x = 14) g/dl. A linear relationship between PbB and slow brain wave voltage during sensory conditioning was observed at initial evaluation and at 2-year follow-up. No significant relationship between PbB and slow wave voltage during passive conditioning was found at the 5-year follow-up, although a linear increase in slow wave negativity relative to the current PbB level during active conditioning was suggested by exploratory analyses. Another exploratory analysis revealed a significant linear relationship between the original PbB levels and the latency of waves III and V of the brainstem auditory evoked potential. The latency of both waves increased as a function of original PbB. Increased latency of these waves is suggestive of subclinical pathology of the auditory pathway rostral to the cochlear nucleus, although end-organ impairment cannot be ruled out. No threshold for the effect of Pb on auditory function was apparent.

Otto, D.; Robinson, G.; Baumann, S.; Schroeder, S.; Mushak, P.; Kleinbaum, D.; Boone, L.

1985-10-01

400

Use of a run-in period to decrease loss to follow-up in the Contact Lens and Myopia Progression (CLAMP) study. | accrualnet.cancer.gov  

Cancer.gov

A run-in period is a time of observation prior to randomization during which potential subjects can be screened for compliance with a treatment regimen. In this study, the run-in period increased the number of compliant participants, decreased losses to follow-up, improved the statistical power of the study, and did not limit the generalizability of the study results.

401

A Multiyear Follow-Up Study Examining the Effectiveness of a Cognitive Behavioral Group Therapy Program on the Recidivism of Juveniles on Probation.  

PubMed

The present study evaluated the long-term effectiveness of a cognitive behavioral group therapy program titled Community Opportunity Growth. This study monitored juvenile delinquents' recidivism across a 7-year time period, with the average length to follow-up being 39 months. It was hypothesized that program graduates (N = 178) would have a significantly lower recidivism rate than a control group (program nonstarters; N = 66) and program dropouts (whose predisposing factors may have influenced their program participation; N = 150). Analyses controlled for sex, ethnicity, age, prior petitions, highest class of prior petition, and months to follow-up. Results show a general trend indicating the long-term effectiveness of the program as graduates had a lower incidence of petitions at follow-up compared with dropouts and fewer petitions compared with the other two groups. PMID:24170185

Jewell, Jeremy D; Malone, Michael D; Rose, Paul; Sturgeon, Dennis; Owens, Sarah

2013-10-29

402

The anterior interosseous nerve syndrome (the Kiloh-Nevin syndrome). Report and follow-up study of three cases.  

PubMed

Three surgically treated cases demonstrate that this syndrome is a compressive neuropathy of the anterior interosseous branch of the median nerve rather than a neuritis, as originally believed. All symptoms were in the dominant hand and included deterioration of handwriting, pain, weakness of the flexor policis longus, the flexor digitorum longus to the index finger, and the pronator quadratus. Electromyograms were abnormal in two of the three cases. All forms of conservative treatment failed over a three- to five-month period. All lesions were demonstrable at surgery, and recovery was complete in all cases within five months of surgery. At an average follow-up evaluation of seven years there was no recurrence in any case. The loss of ability to write was characteristic of all three cases and is being reported for the first time. PMID:6744722

Stern, M B

1984-01-01

403

A clinico-pathological and follow up study of 10 cases of essential type II cryoglobulinaemic neuropathy.  

PubMed Central

Ten patients with essential cryoglobulinaemia type II were examined for peripheral nerve damage. In six cases distal symmetrical nerve involvement was present, while in three other cases abnormalities restricted to single nerves were found. Electrophysiological and morphological data were consistent with axonal damage, the larger myelinated fibres being most affected. Although active signs of vasculitis and immunoperoxidase staining for immunoglobulins were not present, endoneurial vessels were widely damaged, with abnormally thick endothelial cells and redundant basal membranes. These findings, together with a patchy distribution of myelinated fibre loss, suggest ischaemia as a cause of peripheral neuropathy during essential cryoglobulinaemia type II. A follow up examination, performed one year after haematologial remission, revealed that no further peripheral nerve damage had occurred. PMID:2176233

Cavaletti, G; Petruccioli, M G; Crespi, V; Pioltelli, P; Marmiroli, P; Tredici, G

1990-01-01

404

Fish oil, selenium, and mercury in relation to incidence of hypertension: a 20-year follow-up study  

PubMed Central

Objectives Long-chain omega-3 polyunsaturated fatty acids (LC?3PUFAs), selenium (Se) and mercury (Hg) are three important components in fish. The cardioprotective effect of LC?3PUFA intake has been recognized; however, the hypothesis that this benefit may be greatest with high Se and low Hg levels has not been investigated. Design A cohort of 4,508 American adults aged 18–30, without hypertension at baseline in 1985, were enrolled. Six follow-ups were conducted at exams in 1987, 1990, 1992, 1995, 2000 and 2005. Diet was assessed by a validated interviewer-administered quantitative food frequency questionnaire at exams in 1985, 1992 and 2005. Incident hypertension was defined as first occurrence at any follow-up examination of systolic blood pressure ? 140 mmHg, diastolic blood pressure ? 90 mmHg, or taking anti-hypertensive medication. Toenail clippings were collected in 1987, and Se and Hg levels were quantified by instrumental neutron-activation analysis. Result Participants in the highest LC?3PUFAintake quartile had a significantly lower incidence of hypertension (Hazard Ratio: 0.65; 95% CI: 0.53–0.79; Ptrend<0.01) compared to those in the lowest quartile after adjustment for potential confounders. Docosahexaenoic acid showed a greater inverse association than eicosapentaenoic acid. The inverse association of LC?3PUFA intake with hypertension appeared more pronounced at higher Se and lower Hg levels, although interaction tests were statistically non-significant. Conclusions Out findings indicated that LC?3PUFA intake was inversely associated with incidence of hypertension. The prior hypothesis that the potential anti-hypertensive effect of LC?3PUFA intake varies depending on joint levels of Se and Hg received modest support, and cannot be ruled out. PMID:21205024

Xun, Pengcheng; Hou, Ningqi; Daviglus, Martha; Liu, Kiang; Morris, J. Steven; Shikany, James M.; Sidney, Stephen; Jacobs, David R.; He, Ka

2010-01-01

405

Acquired haemophilia A. First line treatment with calcineurin inhibitors and steroid pulses: a 10-year follow-up study.  

PubMed

Acquired haemophilia A (AH) is defined as the presence of autoantibodies or inhibitors against factor VIII (FVIII) with a clinical bleeding onset that can be life-threatening. Immunosuppressant therapy must be initiated rapidly to eradicate the inhibitor. Current treatments based on steroids plus cyclophosphamide or rituximab are quite effective, but with significant side-effects. Based on previous described AH cases treated with cyclosporine, with a good side-effect profile, we aimed at assessing prospectively a first-line calcineurin inhibitor based immunosuppressive therapy. We included a total of 11 patients affected with AH. Once diagnosed, pulse steroids and calcineurin inhibitors were started. Time to achieve sustained response (SR), defined as testing negative for inhibitor and with stable FVIII level >50%, immunosuppressant side-effects, and relapse of AH were evaluated. Eight patients received cyclosporine and three patients received tacrolimus. SR was achieved in 10 of 11 patients (90.9%) in a median time of 3 weeks (range 2-8 weeks), and none of them relapsed during a median follow-up time of 14 months (range 4-120). One major side-effect appeared (posterior encephalopathy) that forced to discontinue cyclosporine. Overall 5-year survival rate was 54.5%, with a total of five patients dying during the follow-up (mortality rate of 45.5%). These five patients had achieved SR and died because of complications of basal morbidities and/or senescence, not related to AH (bleeding) or to immunosuppressant's (infection) side-effects. Combination therapy of calcineurin inhibitors and pulse steroids seems clinically effective as a first-line treatment of AH. PMID:22429259

Pardos-Gea, J; Altisent, C; Parra, R; Vilardell-Tarrès, M; Ordi-Ros, J

2012-09-01

406

A Six-Year Follow-Up Study of Social Network Changes among African-American, Caribbean, and U.S.-Born Caucasian Urban Older Adults  

ERIC Educational Resources Information Center

This study explores dynamic changes in network size and composition by examining patterns of older adults' social network change over time, that is: types of movements; the reason for the loss of network members; and the relation of movement and composition in concert. This study is a 6-year follow up of changes in the social networks of U.S.-Born…

Conway, Francine; Magai, Carol; Jones, Samuel; Fiori, Katherine; Gillespie, Michael

2013-01-01

407

Development of children with autism spectrum disorders in special needs education schools in the Netherlands: a three-year follow-up study  

Microsoft Academic Search

The purpose of the study was to investigate the development of symptomatology and academic growth of children with autism spectrum disorders (ASD) attending a special needs education school in the Netherlands as well as to explore the relationship between academic achievement and symptom reduction of those children. To this end a three-year follow up study was conducted by using multiple

Eirini Manti; Evert M. Scholte; Ina A. Van Berckelaer-Onnes

2011-01-01

408

Excess Mortality and Causes of Death in Autism Spectrum Disorders: A Follow up of the 1980s Utah/UCLA Autism Epidemiologic Study  

ERIC Educational Resources Information Center

This study's purpose was to investigate mortality among individuals with autism spectrum disorders (ASD) ascertained during a 1980s statewide autism prevalence study (n = 305) in relation to controls. Twenty-nine of these individuals (9.5 %) died by the time of follow up, representing a hazard rate ratio of 9.9 (95 % CI 5.7-17.2) in relation to…

Bilder, Deborah; Botts, Elizabeth L.; Smith, Ken R.; Pimentel, Richard; Farley, Megan; Viskochil, Joseph; McMahon, William M.; Block, Heidi; Ritvo, Edward; Ritvo, Riva-Ariella; Coon, Hilary

2013-01-01

409

Continuity, Comorbidity and Longitudinal Associations between Depression and Antisocial Behaviour in Middle Adolescence: A 2-Year Prospective Follow-Up Study  

ERIC Educational Resources Information Center

The study investigated continuity, comorbidity and longitudinal associations between depression Beck depression inventory (RBDI) and antisocial behaviour Youth self-report (YSR) in middle adolescence. Data were used from a community sample of 2070 adolescents who participated in a 2-year prospective follow-up study. The results indicate that both…

Ritakallio, Minna; Koivisto, Anna-Maija; von der Pahlen, Bettina; Pelkonen, Mirjami; Marttunen, Mauri; Kaltiala-Heino, Riittakerttu

2008-01-01

410

Assessing the Long-Term Effects of EMDR: Results from an 18-Month Follow-Up Study with Adult Female Survivors of CSA  

ERIC Educational Resources Information Center

This 18-month follow-up study builds on the findings of a randomized experimental evaluation that found qualified support for the short-term effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) in reducing trauma symptoms among adult female survivors of childhood sexual abuse (CSA). The current study provides preliminary evidence…

Edmond, Tonya; Rubin, Allen

2004-01-01

411

High School Longitudinal Study of 2009 (HSLS:09) First Follow-Up: A First Look at Fall 2009 Ninth-Graders in 2012. NCES 2014-360  

ERIC Educational Resources Information Center

This report provides a first look at selected findings from the first follow-up of the High School Longitudinal Study of 2009 (HSLS:09). HSLS:09 focuses on understanding students' trajectories from the beginning of high school into higher education and the workforce. The core research questions for the study explore secondary to postsecondary…

Ingels, Steven J.; Dalton, Ben

2013-01-01

412

A Cognitive- Behavioral Therapeutic Program for Patients with Obesity and Binge Eating Disorder: Short- and Long- Term Follow-Up Data of a Prospective Study  

ERIC Educational Resources Information Center

The goal of this study is to investigate the efficacy of a manualized cognitive-behavioral therapeutic (CBT) approach for patients with obesity and binge eating disorder (BED) on the short and longer term. A prospective study without a control group consisting of three measurements (a baseline measurement and two follow-up assessments up to 5…

Vanderlinden, Johan; Adriaensen, An; Vancampfort, Davy; Pieters, Guido; Probst, Michel; Vansteelandt, Kristof

2012-01-01

413

Community College Students: Where Do They Go and What Do They Do? A 5-Year Statewide Follow-Up Study. AIR 1992 Annual Forum Paper.  

ERIC Educational Resources Information Center

This paper describes the results of a 5-year statewide follow-up study of first-time, full-time community college students in Kansas, and documents the academic and career progress of these students from first entry into college to subsequent experiences after leaving the community college. The study, which began with 640 participants from 17…

Conklin, Karen A.

414

Who Is Physically Active? Cultural Capital and Sports Participation from Adolescence to Middle Age--A 38-Year Follow-Up Study  

ERIC Educational Resources Information Center

Background: Many studies have found that there is a low-to-moderate association between exercise during adolescence and exercise habits in adulthood. A question that arises from these earlier studies, with a follow-up period of about five to 20 years, is how children's and adolescents' physical activity affects their inclination to exercise later…

Engstrom, Lars-Magnus

2008-01-01

415

Follow-up study of patients randomized in the scandinavian simvastatin survival study (4S) of cholesterol lowering  

Microsoft Academic Search

The Scandinavian Simvastatin Survival Study (4S) and other randomized clinical trials have demonstrated that cholesterol-lowering treatment with statins improves prognosis in patients with coronary atherosclerosis compared with placebo. The effect of therapy with statins beyond the typical 5 to 6 years’ duration of the trials, in particular regarding the risk of cancer, has not been investigated. This study examines the

Terje R. Pedersen; Lars Wilhelmsen; Ole Færgeman; Timo E. Strandberg; Gudmundur Thorgeirsson; Linda Troedsson; Johan Kristianson; Kåre Berg; Thomas J. Cook; Torben Haghfelt; John Kjekshus; Tatu Miettinen; Anders G. Olsson; Kalevi Pyörälä; Hans Wedel

2000-01-01

416

The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years  

Microsoft Academic Search

Objectives:The long-term prognosis of non-alcoholic fatty liver disease (NAFLD) in children remains uncertain. We aimed at determining the long-term outcomes and survival of children with NAFLD.Design:Retrospective longitudinal hospital-based cohort study.Patients:Sixty-six children with NAFLD (mean age 13.9 (SD 3.9) years) were followed up for up to 20 years with a total of 409.6 person-years of follow-up.Results:The metabolic syndrome was present in

A E Feldstein; P Charatcharoenwitthaya; S Treeprasertsuk; J T Benson; F B Enders; P Angulo

2009-01-01

417

Black Women's Health Study (BWHS): A Follow-up Study for Causes of Illness in Black Women  

Cancer.gov

The Black Women's Health Study (BWHS) cohort was established in 1995 when 59,000 black women ages 21 to 69 years from all regions of the United States completed mail questionnaires providing data on a wide range of factors.

418

Inquiry Follow-Up  

ERIC Educational Resources Information Center

It is exciting to see children display an interest in discovering the world through their actions. Those actions are the beginning of science inquiry, the process children use to develop knowledge and understanding of scientific ideas, including an understanding of how scientists study the natural world. This month's column features an activity…

Ashbrook, Peggy

2011-01-01

419

Risk Factors for the Recurrence of the Congenital Diaphragmatic Hernia-Report from the Long-Term Follow-Up Study of Japanese CDH Study Group.  

PubMed

Aim of the Study?Few follow-up studies focused on the recurrence regarding the postoperative course of congenital diaphragmatic hernia (CDH) survivors. The aim of this study was to report on risk factor for CDH patients who had the recurrence during the follow-up. Materials and Methods?A multicenter retrospective survey was conducted on neonates diagnosed to have CDH between January 2006 and December 2010. Follow-up survey was conducted between September 2013 and October 2013 (ethical approval: No. 25-222). Nine institutions agreed to participate in this survey. Out of 228, 182 (79.8%) patients were alive and 180 patients were included in this study. Two patients were excluded because the defect had not repaired at the primary operation. The patients were divided into the recurrence group (n?=?21) and the nonrecurrence group (n?=?159). Postnatal and postoperative variables were compared between these two groups. Baseline variables which showed significance in univariate analysis were entered into multiple logistic regression analysis for analyzing the recurrence. A value of p?follow-up. Five (2.8%) patients had the recurrence before primary discharge and 16 (8.9%) patients had the recurrence after discharge. Univariate analysis showed that liver herniation (crude odds ratio [OR], 7.4; 95% confidence interval [CI], 2.73-23.68), defect size C and D, proposed by the CDH Study Group (crude OR, 7.09; 95% CI, 2.73-19.99) and patch repair (crude OR, 5.00; 95% CI, 1.91-14.70) were risk factors. Multivariate logistic regression analysis showed liver herniation (adjusted OR, 3.96; 95% CI, 1.01-16.92) was the risk factor for the recurrence. Conclusion?A wide spectrum of the disease severity and the rarity of the disease mask the risk of the recurrence for CDH patients. This study showed the only factor to predict the recurrence was the liver herniation. These data will be helpful for providing information for the long-term follow-up of the CDH patients. PMID:25526606

Nagata, Kouji; Usui, Noriaki; Terui, Keita; Takayasu, Hajime; Goishi, Keiji; Hayakawa, Masahiro; Tazuke, Yuko; Yokoi, Akiko; Okuyama, Hiroomi; Taguchi, Tomoaki

2015-02-01

420

Follow-up Study of Educational Aides Graduates 1971-1974. Research Study No. 75-4.  

ERIC Educational Resources Information Center

This study summarizes responses to a questionnaire sent to graduates of the Educational Aide program, an off-campus program conducted by Los Angeles City College (LACC). The Educational Aide program was designed to upgrade skills and knowledge for individuals employed to assist teachers in the classroom, on the playground, and in several…

Gold, Ben K.

421

The Center for the Arts and Sciences: Long-Term Follow-Up Study of 1987 and 1988 Graduates. Evaluation Report.  

ERIC Educational Resources Information Center

Findings of a follow-up study that examined the experiences of the 1987 and 1988 graduates of the Center for the Arts and Sciences (CAS) program in Saginaw, Michigan, are presented in this paper. A survey mailed to a total of 78 program graduates, 36 from 1987 and 42 from 1988, elicited 21 responses, the majority of whom were from white females.…

Saginaw Public Schools, MI. Dept. of Evaluation Services.

422

Blood Pressure Reactions to Acute Psychological Stress and Future Blood Pressure Status: A 10Year Follow-Up of Men in the Whitehall II Study  

Microsoft Academic Search

Objective: The aim of this study was to examine whether blood pressure reactions to mental stress predicted future blood pressure and hypertension. Methods: Blood pressure was recorded at an initial medical screening examina- tion after which blood pressure reactions to a mental stress task were determined. A follow-up screening assessment of blood pressure and antihypertensive medication status was undertaken 10

DOUGLAS CARROLL; GEORGE DAVEY SMITH; MARTIN J. SHIPLEY; ERIC J. BRUNNER; MICHAEL G. MARMOT

423

Results of the cementless Plasmacup in revision total hip arthroplasty: a retrospective study of 72 cases with an average follow-up of eight years  

Microsoft Academic Search

BACKGROUND: There are multiple revision implant systems currently available for socket revision in revision total hip arthroplasty. Up until now, not all of these systems have been followed up with regards to their long-term use as a revision implantation. For the first time, this study presents the hemispherical porous-coated socket Plasmacup SC, produced by Aesculap, Tuttlingen, Germany, and the clinical

Stefan Lakemeier; Guenter Aurand; Nina Timmesfeld; Thomas J Heyse; Susanne Fuchs-Winkelmann; Markus D Schofer

2010-01-01

424

Follow-up on a 1962 case-control study of trace elements as risk factors for stomach cancer in Iceland  

Microsoft Academic Search

In 1988 a follow-up investigation was made of a case-control study conducted in 1962 in Iceland which tested hypotheses that trace elements in pasture grass, drinking water and cow's milk were associated through diet with cancer of the stomach. Samples were collected in 1962 from 26 farms in the northern county of Skagafjardarsysla and 30 farms in the southern county

R. W. Armstrong

1990-01-01

425

EFFECTS OF LOW TO MODERATE LEAD EXPOSURE ON SLOW CORTICAL POTENTIALS IN YOUNG CHILDREN: TWO YEAR FOLLOW-UP STUDY (JOURNAL VERSION)  

EPA Science Inventory

A follow-up study of slow cortical potentials in children with elevated blood lead (PbB) histories was conducted two years after initial evaluation. An age x PbB interaction was again observed wherein slow wave (SW) voltage varied as a linear function of PbB with the slope of the...

426

Alcohol consumption and mortality from all causes, coronary heart disease, and stroke: results from a prospective cohort study of Scottish men with 21 years of follow up  

Microsoft Academic Search

Objectives To relate alcohol consumption to mortality. Design Prospective cohort study. Setting 27 workplaces in the west of Scotland. Participants 5766 men aged 35›64 when screened in 1970›3 who answered questions on their usual weekly alcohol consumption. Main outcome measures Mortality from all causes, coronary heart disease, stroke, and alcohol related causes over 21 years of follow up related to

Carole L Hart; George Davey Smith; David J Hole; Victor M Hawthorne; George Davey

1999-01-01

427

Follow-Up Study of Ex-Students of a Residential School for Children with Emotional and Behavioural Difficulties in New Zealand  

ERIC Educational Resources Information Center

A follow-up study was conducted on ex-students of a residential special school for children with emotional and behavioural difficulties in New Zealand. Previous research on post-school outcomes for students with emotional and behavioural difficulties has found low levels on quality of life indicators such as education, employment and community…

Hornby, Garry; Witte, Chrystal

2008-01-01

428

Chromosomal radiosensitivity and acute radiation side effects after radiotherapy in tumour patients - a follow-up study  

PubMed Central

Background Radiotherapists are highly interested in optimizing doses especially for patients who tend to suffer from side effects of radiotherapy (RT). It seems to be helpful to identify radiosensitive individuals before RT. Thus we examined aberrations in FISH painted chromosomes in in vitro irradiated blood samples of a group of patients suffering from breast cancer. In parallel, a follow-up of side effects in these patients was registered and compared to detected chromosome aberrations. Methods Blood samples (taken before radiotherapy) were irradiated in vitro with 3 Gy X-rays and analysed by FISH-painting to obtain aberration frequencies of first cycle metaphases for each patient. Aberration frequencies were analysed statistically to identify individuals with an elevated or reduced radiation response. Clinical data of patients have been recorded in parallel to gain knowledge on acute side effects of radiotherapy. Results Eight patients with a significantly elevated or reduced aberration yield were identified by use of a t-test criterion. A comparison with clinical side effects revealed that among patients with elevated aberration yields one exhibited a higher degree of acute toxicity and two patients a premature onset of skin reaction already after a cumulative dose of only 10 Gy. A significant relationship existed between translocations in vitro and the time dependent occurrence of side effects of the skin during the therapy period. Conclusions The results suggest that translocations can be used as a test to identify individuals with a potentially elevated radiosensitivity. PMID:21473753

2011-01-01

429

Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study.  

PubMed

Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart dis