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Sample records for 17-story multifunctional residential

  1. Structural Concept and Analysis of a 17-Story Multifunctional Residential Complex with and without Seismic Isolation System

    SciTech Connect

    Melkumyan, Mikayel; Gevorgyan, Emma

    2008-07-08

    In recent years seismic isolation technologies in Armenia were extensively applied in construction of multistory buildings. These are 10-17-story residential complexes with parking floors and with floors envisaged for offices, shopping centers, fitness clubs, etc. Also there is a 20-story business centre designed in 2006, which is currently under construction. All mentioned complexes are briefly described in the paper, which is, however, mainly dedicated to the 17-story residential complex designed in 2007. The structural concept, including the new approach on installation of seismic isolation rubber bearings in this building, is described and detailed results of the earthquake response analysis for two cases, i.e. when the building is base isolated and when it has a fixed base, are given. Several time histories were used in the analysis and for both cases the building was analyzed also according to the requirements of the Armenian Seismic Code. Comparison of the obtained results indicates the high effectiveness of the proposed structural concept of isolation system and the need for further improvement of Seismic Code provisions regarding the values of the reduction factors.

  2. Structural Concept and Analysis of a 17-Story Multifunctional Residential Complex with and without Seismic Isolation System

    NASA Astrophysics Data System (ADS)

    Melkumyan, Mikayel; Gevorgyan, Emma

    2008-07-01

    In recent years seismic isolation technologies in Armenia were extensively applied in construction of multistory buildings. These are 10-17-story residential complexes with parking floors and with floors envisaged for offices, shopping centers, fitness clubs, etc. Also there is a 20-story business centre designed in 2006, which is currently under construction. All mentioned complexes are briefly described in the paper, which is, however, mainly dedicated to the 17-story residential complex designed in 2007. The structural concept, including the new approach on installation of seismic isolation rubber bearings in this building, is described and detailed results of the earthquake response analysis for two cases, i.e. when the building is base isolated and when it has a fixed base, are given. Several time histories were used in the analysis and for both cases the building was analyzed also according to the requirements of the Armenian Seismic Code. Comparison of the obtained results indicates the high effectiveness of the proposed structural concept of isolation system and the need for further improvement of Seismic Code provisions regarding the values of the reduction factors.

  3. Multifunctional nanocrystals

    DOEpatents

    Klimov, Victor I.; Hollingsworth, Jennifer A.; Crooker, Scott A.; Kim, Hyungrak

    2010-06-22

    Multifunctional nanocomposites are provided including a core of either a magnetic material or an inorganic semiconductor, and, a shell of either a magnetic material or an inorganic semiconductor, wherein the core and the shell are of differing materials, such multifunctional nanocomposites having multifunctional properties including magnetic properties from the magnetic material and optical properties from the inorganic semiconductor material. Various applications of such multifunctional nanocomposites are also provided.

  4. Multifunctional nanocrystals

    DOEpatents

    Klimov, Victor I.; Hollingsworth, Jennifer A.; Crooker, Scott A.; Kim, Hyungrak

    2007-08-28

    Multifunctional nanocomposites are provided including a core of either a magnetic material or an inorganic semiconductor, and, a shell of either a magnetic material or an inorganic semiconductor, wherein the core and the shell are of differing materials, such multifunctional nanocomposites having multifunctional properties including magnetic properties from the magnetic material and optical properties from the inorganic semiconductor material. Various applications of such multifunctional nanocomposites are also provided.

  5. Multifunctional thin film surface

    SciTech Connect

    Brozik, Susan M.; Harper, Jason C.; Polsky, Ronen; Wheeler, David R.; Arango, Dulce C.; Dirk, Shawn M.

    2015-10-13

    A thin film with multiple binding functionality can be prepared on an electrode surface via consecutive electroreduction of two or more aryl-onium salts with different functional groups. This versatile and simple method for forming multifunctional surfaces provides an effective means for immobilization of diverse molecules at close proximities. The multifunctional thin film has applications in bioelectronics, molecular electronics, clinical diagnostics, and chemical and biological sensing.

  6. Multifunctional cellulase and hemicellulase

    SciTech Connect

    Fox, Brian G.; Takasuka, Taichi; Bianchetti, Christopher M.

    2015-09-29

    A multifunctional polypeptide capable of hydrolyzing cellulosic materials, xylan, and mannan is disclosed. The polypeptide includes the catalytic core (cc) of Clostridium thermocellum Cthe_0797 (CelE), the cellulose-specific carbohydrate-binding module CBM3 of the cellulosome anchoring protein cohesion region (CipA) of Clostridium thermocellum (CBM3a), and a linker region interposed between the catalytic core and the cellulose-specific carbohydrate binding module. Methods of using the multifunctional polypeptide are also disclosed.

  7. Residential Plumbing.

    ERIC Educational Resources Information Center

    Barclay, Leney

    This twenty-nine-unit residential plumbing curriculum contains teacher and student materlals based on the Vocational-Technical Education Consortium of States (V-TECS) Plumbing Catalog of Performance Objectives, Performance Guides, and Tool and Equipment Lists. An introduction contains a V-TECS task listing showing the relationship between the…

  8. Residential Wiring.

    ERIC Educational Resources Information Center

    Taylor, Mark

    The second in a series of three curriculum packages on wiring, these materials for a five-unit course were developed to prepare postsecondary students for entry-level employment in the residential wiring trade. The five units are: (1) blueprint reading and load calculations; (2) rough-in; (3) service; (4) trim out and troubleshooting; and (5) load…

  9. Multifunctional Tanks for Spacecraft

    NASA Technical Reports Server (NTRS)

    Collins, David H.; Lewis, Joseph C.; MacNeal, Paul D.

    2006-01-01

    A document discusses multifunctional tanks as means to integrate additional structural and functional efficiencies into designs of spacecraft. Whereas spacecraft tanks are traditionally designed primarily to store fluids and only secondarily to provide other benefits, multifunctional tanks are designed to simultaneously provide multiple primary benefits. In addition to one or more chamber(s) for storage of fluids, a multifunctional tank could provide any or all of the following: a) Passageways for transferring the fluids; b) Part or all of the primary structure of a spacecraft; c) All or part of an enclosure; d) Mechanical interfaces to components, subsystems, and/or systems; e) Paths and surfaces for transferring heat; f)Shielding against space radiation; j) Shielding against electromagnetic interference; h) Electrically conductive paths and surfaces; and i) Shades and baffles to protect against sunlight and/or other undesired light. Many different multifunctional-tank designs are conceivable. The design of a particular tank can be tailored to the requirements for the spacecraft in which the tank is to be installed. For example, the walls of the tank can be flat or curved or have more complicated shapes, and the tank can include an internal structure for strengthening the tank and/or other uses.

  10. Contractive multifunctions, fixed point inclusions and iterated multifunction systems

    NASA Astrophysics Data System (ADS)

    Kunze, H. E.; La Torre, D.; Vrscay, E. R.

    2007-06-01

    We study the properties of multifunction operators that are contractive in the Covitz-Nadler sense. In this situation, such operators T possess fixed points satisfying the relation x[set membership, variant]Tx. We introduce an iterative method involving projections that guarantees convergence from any starting point x0[set membership, variant]X to a point x[set membership, variant]XT, the set of all fixed points of a multifunction operator T. We also prove a continuity result for fixed point sets XT as well as a "generalized collage theorem" for contractive multifunctions. These results can then be used to solve inverse problems involving contractive multifunctions. Two applications of contractive multifunctions are introduced: (i) integral inclusions and (ii) iterated multifunction systems.

  11. Multifunctional nanocomposite materials

    SciTech Connect

    Roy, R.; Komarneni, S.

    1991-11-01

    Objective is to examine the low temperature nanocomposite route in the synthesis of multifunctional materials using two-dimensional clays as hosts. After about 8 months, a significant advance was made in the design and synthesis of novel nanocomposite materials, which are nanometal intercalated clays prepared by a low temperature route. A layered V[sub 2]O[sub 5] gel has been made hydrothermally and its cation exchange properties measured. Several pillared clays have also been synthesized and characterized.

  12. Multifunctional imaging nanoprobes

    PubMed Central

    Jarzyna, Peter A.; Gianella, Anita; Skajaa, Torjus; Knudsen, Gitte; Deddens, Lisette H.; Cormode, David P.; Fayad, Zahi A.; Mulder, Willem J. M.

    2011-01-01

    Multifunctional imaging nanoprobes have proven to be of great value in the research of pathological processes, as well as the assessment of the delivery, fate, and therapeutic potential of encapsulated drugs. Moreover, such probes may potentially support therapy schemes by the exploitation of their own physical properties, e.g., through thermal ablation. This review will present four classes of nanoparticulate imaging probes used in this area: multifunctional probes (1) that can be tracked with at least three different and complementary imaging techniques, (2) that carry a drug and have bimodal imaging properties, (3) that are employed for nucleic acid delivery and imaging, and (4) imaging probes with capabilities that can be used for thermal ablation. We will highlight several examples where the suitable combination of different (bio)materials like polymers, inorganic nanocrystals, fluorophores, proteins/peptides, and lipids can be tailored to manufacture multifunctional probes to accomplish nanomaterials of each of the aforementioned classes. Moreover, it will be demonstrated how multimodality imaging approaches improve our understanding of in vivo nanoparticle behavior and efficacy at different levels, ranging from the subcellular level to the whole body. PMID:20039335

  13. Templated biomimetic multifunctional coatings

    NASA Astrophysics Data System (ADS)

    Sun, Chih-Hung; Gonzalez, Adriel; Linn, Nicholas C.; Jiang, Peng; Jiang, Bin

    2008-02-01

    We report a bioinspired templating technique for fabricating multifunctional optical coatings that mimic both unique functionalities of antireflective moth eyes and superhydrophobic cicada wings. Subwavelength-structured fluoropolymer nipple arrays are created by a soft-lithography-like process. The utilization of fluoropolymers simultaneously enhances the antireflective performance and the hydrophobicity of the replicated films. The specular reflectivity matches the optical simulation using a thin-film multilayer model. The dependence of the size and the crystalline ordering of the replicated nipples on the resulting antireflective properties have also been investigated by experiment and modeling. These biomimetic materials may find important technological application in self-cleaning antireflection coatings.

  14. Multifunctional reference electrode

    DOEpatents

    Redey, L.; Vissers, D.R.

    1981-12-30

    A multifunctional, low mass reference electrode of a nickel tube, thermocouple means inside the nickel tube electrically insulated therefrom for measuring the temperature thereof, a housing surrounding the nickel tube, an electrolyte having a fixed sulfide ion activity between the housing and the outer surface of the nickel tube forming the nickel/nickel sulfide/sulfide half-cell are described. An ion diffusion barrier is associated with the housing in contact with the electrolyte. Also disclosed is a cell using the reference electrode to measure characteristics of a working electrode.

  15. Multifunctional reference electrode

    DOEpatents

    Redey, Laszlo; Vissers, Donald R.

    1983-01-01

    A multifunctional, low mass reference electrode of a nickel tube, thermocouple means inside the nickel tube electrically insulated therefrom for measuring the temperature thereof, a housing surrounding the nickel tube, an electrolyte having a fixed sulfide ion activity between the housing and the outer surface of the nickel tube forming the nickel/nickel sulfide/sulfide half-cell. An ion diffusion barrier is associated with the housing in contact with the electrolyte. Also disclosed is a cell using the reference electrode to measure characteristics of a working electrode.

  16. Hierarchical multifunctional nanocomposites

    NASA Astrophysics Data System (ADS)

    Ghasemi-Nejhad, Mehrdad N.

    2014-03-01

    Nanocomposites; including nano-materials such as nano-particles, nanoclays, nanofibers, nanotubes, and nanosheets; are of significant importance in the rapidly developing field of nanotechnology. Due to the nanometer size of these inclusions, their physicochemical characteristics differ significantly from those of micron size and bulk materials. The field of nanocomposites involves the study of multiphase materials where at least one of the constituent phases has one dimension less than 100 nm. This is the range where the phenomena associated with the atomic and molecular interaction strongly influence the macroscopic properties of materials. Since the building blocks of nanocomposites are at nanoscale, they have an enormous surface area with numerous interfaces between the two intermix phases. The special properties of the nano-composite arise from the interaction of its phases at the interface and/or interphase regions. By contrast, in a conventional composite based on micrometer sized filler such as carbon fibers, the interfaces between the filler and matrix constitutes have a much smaller surface-to-volume fraction of the bulk materials, and hence influence the properties of the host structure to a much smaller extent. The optimum amount of nanomaterials in the nanocomposites depends on the filler size, shape, homogeneity of particles distribution, and the interfacial bonding properties between the fillers and matrix. The promise of nanocomposites lies in their multifunctionality, i.e., the possibility of realizing unique combination of properties unachievable with traditional materials. The challenges in reaching this promise are tremendous. They include control over the distribution in size and dispersion of the nanosize constituents, and tailoring and understanding the role of interfaces between structurally or chemically dissimilar phases on bulk properties. While the properties of the matrix can be improved by the inclusions of nanomaterials, the

  17. Multi-functional windows

    NASA Astrophysics Data System (ADS)

    Nag, Nagendra; Goldman, Lee M.; Balasubramanian, Sreeram; Sastri, Suri

    2013-06-01

    The requirements for modern aircraft are driving the need for conformal windows for future sensor systems. However, limitations on optical systems and the physical properties of optically transparent materials currently limit the geometry of existing windows and window assemblies to faceted assemblies of flat windows held in weight bearing frames. Novel material systems will have to be developed which combine different materials (e.g. ductile metals with transparent ceramics) into structures that combine transparency with structural integrity. Surmet's demonstrated ability to produce novel transparent ceramic/metal structures will allow us to produce such structures in the types of conformal shapes required for future aircraft applications. Furthermore, the ability to incorporate transparencies into such structures also holds out the promise of creating multi-functional windows which provide a broad range of capabilities that might include RF antennas and de-icing in addition to transparency. Recent results in this area will be presented.

  18. Comet: Multifunction VOEvent broker

    NASA Astrophysics Data System (ADS)

    Swinbank, John

    2014-04-01

    Comet is a Python implementation of the VOEvent Transport Protocol (VTP). VOEvent is the IVOA system for describing transient celestial events. Details of transients detected by many projects, including Fermi, Swift, and the Catalina Sky Survey, are currently made available as VOEvents, which is also the standard alert format by future facilities such as LSST and SKA. The core of Comet is a multifunction VOEvent broker, capable of receiving events either by subscribing to one or more remote brokers or by direct connection from authors; it can then both process those events locally and forward them to its own subscribers. In addition, Comet provides a tool for publishing VOEvents to the global VOEvent backbone.

  19. Protein Multifunctionality: Principles and Mechanisms

    PubMed Central

    Zaretsky, Joseph Z.; Wreschner, Daniel H.

    2008-01-01

    In the review, the nature of protein multifunctionality is analyzed. In the first part of the review the principles of structural/functional organization of protein are discussed. In the second part, the main mechanisms involved in development of multiple functions on a single gene product(s) are analyzed. The last part represents a number of examples showing that multifunctionality is a basic feature of biologically active proteins. PMID:21566747

  20. Leasing Residential PV Systems

    SciTech Connect

    Rutberg, Michael; Bouza, Antonio

    2013-11-01

    The article discusses the adoption, consequences and current market status of the leasing of residential photovoltaic systems. It addresses attributed energy savings and market potential of residential system leasing.

  1. Multifunctional layered magnetic composites.

    PubMed

    Siglreitmeier, Maria; Wu, Baohu; Kollmann, Tina; Neubauer, Martin; Nagy, Gergely; Schwahn, Dietmar; Pipich, Vitaliy; Faivre, Damien; Zahn, Dirk; Fery, Andreas; Cölfen, Helmut

    2015-01-01

    A fabrication method of a multifunctional hybrid material is achieved by using the insoluble organic nacre matrix of the Haliotis laevigata shell infiltrated with gelatin as a confined reaction environment. Inside this organic scaffold magnetite nanoparticles (MNPs) are synthesized. The amount of MNPs can be controlled through the synthesis protocol therefore mineral loadings starting from 15 wt % up to 65 wt % can be realized. The demineralized organic nacre matrix is characterized by small-angle and very-small-angle neutron scattering (SANS and VSANS) showing an unchanged organic matrix structure after demineralization compared to the original mineralized nacre reference. Light microscopy and confocal laser scanning microscopy studies of stained samples show the presence of insoluble proteins at the chitin surface but not between the chitin layers. Successful and homogeneous gelatin infiltration in between the chitin layers can be shown. The hybrid material is characterized by TEM and shows a layered structure filled with MNPs with a size of around 10 nm. Magnetic analysis of the material demonstrates superparamagnetic behavior as characteristic for the particle size. Simulation studies show the potential of collagen and chitin to act as nucleators, where there is a slight preference of chitin over collagen as a nucleator for magnetite. Colloidal-probe AFM measurements demonstrate that introduction of a ferrogel into the chitin matrix leads to a certain increase in the stiffness of the composite material. PMID:25671158

  2. Multifunctional layered magnetic composites

    PubMed Central

    Siglreitmeier, Maria; Wu, Baohu; Kollmann, Tina; Neubauer, Martin; Nagy, Gergely; Schwahn, Dietmar; Pipich, Vitaliy; Faivre, Damien; Zahn, Dirk; Fery, Andreas

    2015-01-01

    Summary A fabrication method of a multifunctional hybrid material is achieved by using the insoluble organic nacre matrix of the Haliotis laevigata shell infiltrated with gelatin as a confined reaction environment. Inside this organic scaffold magnetite nanoparticles (MNPs) are synthesized. The amount of MNPs can be controlled through the synthesis protocol therefore mineral loadings starting from 15 wt % up to 65 wt % can be realized. The demineralized organic nacre matrix is characterized by small-angle and very-small-angle neutron scattering (SANS and VSANS) showing an unchanged organic matrix structure after demineralization compared to the original mineralized nacre reference. Light microscopy and confocal laser scanning microscopy studies of stained samples show the presence of insoluble proteins at the chitin surface but not between the chitin layers. Successful and homogeneous gelatin infiltration in between the chitin layers can be shown. The hybrid material is characterized by TEM and shows a layered structure filled with MNPs with a size of around 10 nm. Magnetic analysis of the material demonstrates superparamagnetic behavior as characteristic for the particle size. Simulation studies show the potential of collagen and chitin to act as nucleators, where there is a slight preference of chitin over collagen as a nucleator for magnetite. Colloidal-probe AFM measurements demonstrate that introduction of a ferrogel into the chitin matrix leads to a certain increase in the stiffness of the composite material. PMID:25671158

  3. Multi-functional composite structures

    DOEpatents

    Mulligan, Anthony C.; Halloran, John; Popovich, Dragan; Rigali, Mark J.; Sutaria, Manish P.; Vaidyanathan, K. Ranji; Fulcher, Michael L.; Knittel, Kenneth L.

    2010-04-27

    Fibrous monolith processing techniques to fabricate multifunctional structures capable of performing more than one discrete function such as structures capable of bearing structural loads and mechanical stresses in service and also capable of performing at least one additional non-structural function.

  4. Multi-functional composite structures

    DOEpatents

    Mulligan, Anthony C.; Halloran, John; Popovich, Dragan; Rigali, Mark J.; Sutaria, Manish P.; Vaidyanathan, K. Ranji; Fulcher, Michael L.; Knittel, Kenneth L.

    2004-10-19

    Fibrous monolith processing techniques to fabricate multifunctional structures capable of performing more than one discrete function such as structures capable of bearing structural loads and mechanical stresses in service and also capable of performing at least one additional non-structural function.

  5. Multifunctional reactive nanocomposite materials

    NASA Astrophysics Data System (ADS)

    Stamatis, Demitrios

    Many multifunctional nanocomposite materials have been developed for use in propellants, explosives, pyrotechnics, and reactive structures. These materials exhibit high reaction rates due to their developed reaction interfacial area. Two applications addressed in this work include nanocomposite powders prepared by arrested reactive milling (ARM) for burn rate modifiers and reactive structures. In burn rate modifiers, addition of reactive nanocomposite powders to aluminized propellants increases the burn rate of aluminum and thus the overall reaction rate of an energetic formulation. Replacing only a small fraction of aluminum by 8Al·MoO3 and 2B·Ti nanocomposite powders enhances the reaction rate with little change to the thermodynamic performance of the formulation; both the rate of pressure rise and maximum pressure measured in the constant volume explosion test increase. For reactive structures, nanocomposite powders with bulk compositions of 8Al·MoO3, 12Al·MoO3, and 8Al·3CuO were prepared by ARM and consolidated using a uniaxial die. Consolidated samples had densities greater than 90% of theoretical maximum density while maintaining their high reactivity. Pellets prepared using 8Al·MoO3 powders were ignited by a CO2 laser. Ignition delays increased at lower laser powers and greater pellet densities. A simplified numerical model describing heating and thermal initiation of the reactive pellets predicted adequately the observed effects of both laser power and pellet density on the measured ignition delays. To investigate the reaction mechanisms in nanocomposite thermites, two types of nanocomposite reactive materials with the same bulk compositions 8Al·MoO3 were prepared by different methods. One of the materials was manufactured by ARM and the other, so called metastable interstitial composite (MIC), by mixing of nano-scaled individual powders. Clear differences in the low-temperature redox reactions, welldetectable by differential scanning calorimetry

  6. Residential Workers' Pack.

    ERIC Educational Resources Information Center

    Rimmer, Alan, Ed.

    The packet of information is intended to help residential workers with disturbed children in the United Kingdom. The first section on theory contains two papers: "Which Children Come Into Residential Care?" (Robin Benians); and "Models of Treatment: Behavioral, Psychodynamic, Cognitive" (Daphne Lennox). The next section contains practical guidance…

  7. Multifunctional nanoparticles for cancer immunotherapy.

    PubMed

    Saleh, Tayebeh; Shojaosadati, Seyed Abbas

    2016-07-01

    During the last decades significant progress has been made in the field of cancer immunotherapy. However, cancer vaccines have not been successful in clinical trials due to poor immunogenicity of antigen, limitations of safety associated with traditional systemic delivery as well as the complex regulation of the immune system in tumor microenvironment. In recent years, nanotechnology-based delivery systems have attracted great interest in the field of immunotherapy since they provide new opportunities to fight the cancer. In particular, for delivery of cancer vaccines, multifunctional nanoparticles present many advantages such as targeted delivery to immune cells, co-delivery of therapeutic agents, reduced adverse outcomes, blocked immune checkpoint molecules, and amplify immune activation via the use of stimuli-responsive or immunostimulatory materials. In this review article, we highlight recent progress and future promise of multifunctional nanoparticles that have been applied to enhance the efficiency of cancer vaccines. PMID:26901287

  8. Multifunctional nanocomposite materials. Progress report

    SciTech Connect

    Roy, R.; Komarneni, S.

    1991-11-01

    Objective is to examine the low temperature nanocomposite route in the synthesis of multifunctional materials using two-dimensional clays as hosts. After about 8 months, a significant advance was made in the design and synthesis of novel nanocomposite materials, which are nanometal intercalated clays prepared by a low temperature route. A layered V{sub 2}O{sub 5} gel has been made hydrothermally and its cation exchange properties measured. Several pillared clays have also been synthesized and characterized.

  9. TES for Residential Settings

    SciTech Connect

    Rutberg, Michael; Hastbacka, Mildred; Bouza, Antonio

    2013-07-31

    The article discusses thermal energy storage approaches for residential buildings. This article addresses both brick bank storage and phase change material technologies. The energy savings and market potential of these thermal energy storage methods are reviewed as well.

  10. Residential photovoltaic system designs

    SciTech Connect

    Russell, M. C.

    1981-01-01

    A project to develop Residential Photovoltaic Systems has begun at Massachusetts Institute of Technology Lincoln Laboratory with the construction and testing of five Prototype Systems. All of these systems utilize a roof-mounted photovoltaic array and allow excess solar-generated electric energy to be fed back to the local utility grid, eliminating the need for on-site storage. Residential photovoltaic system design issues are discussed and specific features of the five Prototype Systems now under test are presented.

  11. Locally rare species influence grassland ecosystem multifunctionality.

    PubMed

    Soliveres, Santiago; Manning, Peter; Prati, Daniel; Gossner, Martin M; Alt, Fabian; Arndt, Hartmut; Baumgartner, Vanessa; Binkenstein, Julia; Birkhofer, Klaus; Blaser, Stefan; Blüthgen, Nico; Boch, Steffen; Böhm, Stefan; Börschig, Carmen; Buscot, Francois; Diekötter, Tim; Heinze, Johannes; Hölzel, Norbert; Jung, Kirsten; Klaus, Valentin H; Klein, Alexandra-Maria; Kleinebecker, Till; Klemmer, Sandra; Krauss, Jochen; Lange, Markus; Morris, E Kathryn; Müller, Jörg; Oelmann, Yvonne; Overmann, Jörg; Pašalić, Esther; Renner, Swen C; Rillig, Matthias C; Schaefer, H Martin; Schloter, Michael; Schmitt, Barbara; Schöning, Ingo; Schrumpf, Marion; Sikorski, Johannes; Socher, Stephanie A; Solly, Emily F; Sonnemann, Ilja; Sorkau, Elisabeth; Steckel, Juliane; Steffan-Dewenter, Ingolf; Stempfhuber, Barbara; Tschapka, Marco; Türke, Manfred; Venter, Paul; Weiner, Christiane N; Weisser, Wolfgang W; Werner, Michael; Westphal, Catrin; Wilcke, Wolfgang; Wolters, Volkmar; Wubet, Tesfaye; Wurst, Susanne; Fischer, Markus; Allan, Eric

    2016-05-19

    Species diversity promotes the delivery of multiple ecosystem functions (multifunctionality). However, the relative functional importance of rare and common species in driving the biodiversity-multifunctionality relationship remains unknown. We studied the relationship between the diversity of rare and common species (according to their local abundances and across nine different trophic groups), and multifunctionality indices derived from 14 ecosystem functions on 150 grasslands across a land-use intensity (LUI) gradient. The diversity of above- and below-ground rare species had opposite effects, with rare above-ground species being associated with high levels of multifunctionality, probably because their effects on different functions did not trade off against each other. Conversely, common species were only related to average, not high, levels of multifunctionality, and their functional effects declined with LUI. Apart from the community-level effects of diversity, we found significant positive associations between the abundance of individual species and multifunctionality in 6% of the species tested. Species-specific functional effects were best predicted by their response to LUI: species that declined in abundance with land use intensification were those associated with higher levels of multifunctionality. Our results highlight the importance of rare species for ecosystem multifunctionality and help guiding future conservation priorities. PMID:27114572

  12. Bi- or multifunctional peptide drugs

    PubMed Central

    Schiller, Peter W.

    2009-01-01

    Strategies for the design of bi- or multifunctional drugs are reviewed. A distinction is made between bifunctional drugs interacting in a monovalent fashion with two targets and ligands containing two distinct pharmacophores binding in a bivalent mode to the two binding sites in a receptor heterodimer. Arguments are presented to indicate that some of the so-called “bivalent” ligands reported in the literature are unlikely to simultaneously interact with two binding sites. Aspects related to the development of bi- or multifunctional drugs are illustrated with examples from the field of opioid analgesics. The drug-like properties of the tetrapeptide Dmt1[DALDA] with triple action as a μ opioid agonist, norepinephrine uptake inhibitor and releaser of endogenous opioid peptides to produce potent spinal analgesia are reviewed. Rationales for the development of opioid peptides with mixed agonist/antagonist profiles as analgesics with reduced side effects are presented. Progress in the development of mixed μ opioid agonist/δ opioid antagonists with low propensity to produce tolerance and physical dependence is reviewed. Efforts to develop bifunctional peptides containing a μ opioid agonist and a cholecystokinin antagonist or an NK1 receptor antagonist as analgesics expected to produce less tolerance and dependence are also reviewed. A strategy to improve the drug-like properties of bifunctional opioid peptide analgesics is presented. PMID:19285088

  13. Multifunction sensor for target recognition

    NASA Astrophysics Data System (ADS)

    James, William M.; Lindberg, Perry C.

    1993-09-01

    The U.S. Army has a critical need for the capability provided by a multifunction sensor. This is (in effect) a smart sensor system that can adapt to environmental conditions and adjust its mode of operation to effectively counter any threat it meets. It will have an intelligent signal processor which has all of the system's sensor signals to choose from. The processor chooses the appropriate signal information to rapidly detect, acquire, track, and automatically identify all targets in the vicinity of the sensor under a wide variety of battlefield scenarios and environmental conditions. The multiphenomenology signal information provides the flexibility to overcome the adverse effects of clutter, countermeasures (both active and passive), illumination, obscurants, target orientation, and weather. It should be noted, however, that the types of sensory information required is dependent on the mission and the operating environment. For instance, a strategic defense sensor operating in space can use (and will need) different types of sensor data than the multifunction sensor employed on an attack helicopter. In fact, the sensor configuration on a helicopter operating in Saudi Arabia may be quite different from one that is deployed to Vietnam. For the purpose of this paper we generalize about the technologies desired for an adaptable, `smart' sensor system. We do not specify a particular mission nor define a specific threat. However, in any case, we can assume the need to fuse sensor signal information in an intelligent processor to provide robust performance in the battlefield environment. 12

  14. Electrospun multifunctional tissue engineering scaffolds

    NASA Astrophysics Data System (ADS)

    Wang, Chong; Wang, Min

    2014-03-01

    Tissue engineering holds great promises in providing successful treatments of human body tissue loss that current methods are unable to treat or unable to achieve satisfactory clinical outcomes. In scaffold-based tissue engineering, a highperformance scaffold underpins the success of a tissue engineering strategy and a major direction in the field is to create multifunctional tissue engineering scaffolds for enhanced biological performance and for regenerating complex body tissues. Electrospinning can produce nanofibrous scaffolds that are highly desirable for tissue engineering. The enormous interest in electrospinning and electrospun fibrous structures by the science, engineering and medical communities has led to various developments of the electrospinning technology and wide investigations of electrospun products in many industries, including biomedical engineering, over the past two decades. It is now possible to create novel, multicomponent tissue engineering scaffolds with multiple functions. This article provides a concise review of recent advances in the R & D of electrospun multifunctional tissue engineering scaffolds. It also presents our philosophy and research in the designing and fabrication of electrospun multicomponent scaffolds with multiple functions.

  15. Multifunctional ORMOSIL and PAA nanoparticles

    NASA Astrophysics Data System (ADS)

    Gupta, Anurag; Rao, K. V. R.; Pera, Paula; Wang, Shouyan J.; Missert, Joseph R.; Ohulchanskyy, Tymish; Roy, Indrajit; Morgan, Janet; Prasad, Paras N.; Kopelman, Raoul; Pandey, Ravindra K.

    2009-06-01

    Various problems arising during molecular imaging of different fluoroprobes and metabolites used in PDT can be circumvented by focusing on multifunctional therapy agents. Thus an effective photo sensitizer coupled with other useful roles to play in PDT treatment make nanoparticles as a good vehicle for different delivery assuming multifunctional roles not only in PDT but also as therapeutic agents for targeted delivery. A new approach is the involving use of 100 nm NPs as photo sensitizers and/or imaging agents. In our Lab., we employ two such NPs and are ORMOSIL (organically Modified Silica) and PAA (Polyacrylamide) which are found to be biologically very safe without disturbing the therapeutic value. The size of the nanoparticles determined by TEM and Dynamic Light Scattering are ~30 nm. These NPs are taken up in conjunction with cyanine dye at near infra red as it has been reported in literature that encapsulated NPs shows very low singlet oxygen production compared with the post-loaded NPs though the reasons are not yet clear. Therefore, we investigated the idea of post-loading or adsorbing vis-a-vis encapsulation.

  16. Building Technologies Residential Survey

    SciTech Connect

    Secrest, Thomas J.

    2005-11-07

    Introduction A telephone survey of 1,025 residential occupants was administered in late October for the Building Technologies Program (BT) to gather information on residential occupant attitudes, behaviors, knowledge, and perceptions. The next section, Survey Results, provides an overview of the responses, with major implications and caveats. Additional information is provided in three appendices as follows: - Appendix A -- Summary Response: Provides summary tabular data for the 13 questions that, with subparts, comprise a total of 25 questions. - Appendix B -- Benchmark Data: Provides a benchmark by six categories to the 2001 Residential Energy Consumption Survey administered by EIA. These were ownership, heating fuel, geographic location, race, household size and income. - Appendix C -- Background on Survey Method: Provides the reader with an understanding of the survey process and interpretation of the results.

  17. Multifunction display system, volume 1

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The design and construction of a multifunction display man/machine interface for use with a 4 pi IBM-360 System are described. The system is capable of displaying superimposed volatile alphanumeric and graphical data on a 512 x 512 element plasma panel, and holographically stored multicolor archival information. The volatile data may be entered from a keyboard or by means of an I/O interface to the 360 system. A 2-page memory local to the display is provided for storing the entered data. The archival data is stored as a phase hologram on a vinyl tape strip. This data is accessible by means of a rapid transport system which responds to inputs provided by the I/O channel on the keyboard. As many as 500 frames may be stored on a tape strip for access in under 6 seconds.

  18. Multifunctionalities driven by ferroic domains

    SciTech Connect

    Yang, J. C.; Huang, Y. L.; Chu, Y. H.; He, Q.

    2014-08-14

    Considerable attention has been paid to ferroic systems in pursuit of advanced applications in past decades. Most recently, the emergence and development of multiferroics, which exhibit the coexistence of different ferroic natures, has offered a new route to create functionalities in the system. In this manuscript, we step from domain engineering to explore a roadmap for discovering intriguing phenomena and multifunctionalities driven by periodic domain patters. As-grown periodic domains, offering exotic order parameters, periodic local perturbations and the capability of tailoring local spin, charge, orbital and lattice degrees of freedom, are introduced as modeling templates for fundamental studies and novel applications. We discuss related significant findings on ferroic domain, nanoscopic domain walls, and conjunct heterostructures based on the well-organized domain patterns, and end with future prospects and challenges in the field.

  19. Synthetic approaches to multifunctional indenes

    PubMed Central

    López-Pérez, Sara; Dinarès, Immaculada

    2011-01-01

    Summary The synthesis of multifunctional indenes with at least two different functional groups has not yet been extensively explored. Among the plausible synthetic routes to 3,5-disubstituted indenes bearing two different functional groups, such as the [3-(aminoethyl)inden-5-yl)]amines, a reasonable pathway involves the (5-nitro-3-indenyl)acetamides as key intermediates. Although several multistep synthetic approaches can be applied to obtain these advanced intermediates, we describe herein their preparation by an aldol-type reaction between 5-nitroindan-1-ones and the lithium salt of N,N-disubstituted acetamides, followed immediately by dehydration with acid. This classical condensation process, which is neither simple nor trivial despite its apparent directness, permits an efficient entry to a variety of indene-based molecular modules, which could be adapted to a range of functionalized indanones. PMID:22238553

  20. Multifunctional composites for energy storage

    NASA Astrophysics Data System (ADS)

    Shuvo, Mohammad Arif I.; Karim, Hasanul; Rajib, Md; Delfin, Diego; Lin, Yirong

    2014-03-01

    Electrochemical super-capacitors have become one of the most important topics in both academia and industry as novel energy storage devices because of their high power density, long life cycles, and high charge/discharge efficiency. Recently, there has been an increasing interest in the development of multifunctional structural energy storage devices such as structural super-capacitors for applications in aerospace, automobiles and portable electronics. These multifunctional structural super-capacitors provide lighter structures combining energy storage and load bearing functionalities. Due to their superior materials properties, carbon fiber composites have been widely used in structural applications for aerospace and automotive industries. Besides, carbon fiber has good electrical conductivity which will provide lower equivalent series resistance; therefore, it can be an excellent candidate for structural energy storage applications. Hence, this paper is focused on performing a pilot study for using nanowire/carbon fiber hybrids as building materials for structural energy storage materials; aiming at enhancing the charge/discharge rate and energy density. This hybrid material combines the high specific surface area of carbon fiber and pseudo-capacitive effect of metal oxide nanowires which were grown hydrothermally in an aligned fashion on carbon fibers. The aligned nanowire array could provide a higher specific surface area that leads to high electrode-electrolyte contact area and fast ion diffusion rates. Scanning Electron Microscopy (SEM) and XRay Diffraction (XRD) measurements were used for the initial characterization of this nanowire/carbon fiber hybrid material system. Electrochemical testing has been performed using a potentio-galvanostat. The results show that gold sputtered nanowire hybrid carbon fiber provides 65.9% better performance than bare carbon fiber cloth as super-capacitor.

  1. Experiential Education, Outdoor Adventure As a Modality in Youth Care and Residential Treatment. A Survey of Programs, Principles, Research and Practice on the European Continent, Especially the Netherlands.

    ERIC Educational Resources Information Center

    Duindam, Ton

    Orthopedagogisch Centrum Michiel is a multifunctional institution in the eastern Netherlands for youth with emotional problems. The staff of the institution's residential treatment center has gradually become involved with outdoor experiential education through training programs, conferences, special projects, and supervised programs. Activities…

  2. Indiana Residential Child Care Study.

    ERIC Educational Resources Information Center

    Brown, Ann L.; Johnson, Marilee

    To compose a comprehensive description of the residential child care needs in Indiana, county agencies, county welfare departments, and probation departments were surveyed. Respondents were asked to identify the characteristics of children placed in Indiana residential facilities, in out-of-state residential care, and of those whom the agency was…

  3. Advanced Multifunctional MMOD Shield: Radiation Shielding Assessment

    NASA Technical Reports Server (NTRS)

    Rojdev, Kristina; Christiansen, Eric

    2013-01-01

    Deep space missions must contend with a harsh radiation environment Impacts to crew and electronics. Need to invest in multifunctionality for spacecraft optimization. MMOD shield. Goals: Increase radiation mitigation potential. Retain overall MMOD shielding performance.

  4. Microbial diversity drives multifunctionality in terrestrial ecosystems

    PubMed Central

    Delgado-Baquerizo, Manuel; Maestre, Fernando T.; Reich, Peter B.; Jeffries, Thomas C.; Gaitan, Juan J.; Encinar, Daniel; Berdugo, Miguel; Campbell, Colin D.; Singh, Brajesh K.

    2016-01-01

    Despite the importance of microbial communities for ecosystem services and human welfare, the relationship between microbial diversity and multiple ecosystem functions and services (that is, multifunctionality) at the global scale has yet to be evaluated. Here we use two independent, large-scale databases with contrasting geographic coverage (from 78 global drylands and from 179 locations across Scotland, respectively), and report that soil microbial diversity positively relates to multifunctionality in terrestrial ecosystems. The direct positive effects of microbial diversity were maintained even when accounting simultaneously for multiple multifunctionality drivers (climate, soil abiotic factors and spatial predictors). Our findings provide empirical evidence that any loss in microbial diversity will likely reduce multifunctionality, negatively impacting the provision of services such as climate regulation, soil fertility and food and fibre production by terrestrial ecosystems. PMID:26817514

  5. Microbial diversity drives multifunctionality in terrestrial ecosystems.

    PubMed

    Delgado-Baquerizo, Manuel; Maestre, Fernando T; Reich, Peter B; Jeffries, Thomas C; Gaitan, Juan J; Encinar, Daniel; Berdugo, Miguel; Campbell, Colin D; Singh, Brajesh K

    2016-01-01

    Despite the importance of microbial communities for ecosystem services and human welfare, the relationship between microbial diversity and multiple ecosystem functions and services (that is, multifunctionality) at the global scale has yet to be evaluated. Here we use two independent, large-scale databases with contrasting geographic coverage (from 78 global drylands and from 179 locations across Scotland, respectively), and report that soil microbial diversity positively relates to multifunctionality in terrestrial ecosystems. The direct positive effects of microbial diversity were maintained even when accounting simultaneously for multiple multifunctionality drivers (climate, soil abiotic factors and spatial predictors). Our findings provide empirical evidence that any loss in microbial diversity will likely reduce multifunctionality, negatively impacting the provision of services such as climate regulation, soil fertility and food and fibre production by terrestrial ecosystems. PMID:26817514

  6. Multifunctional imaging probe based on gadofulleride nanoplatform

    NASA Astrophysics Data System (ADS)

    Zheng, Jun-Peng; Liu, Qiao-Ling; Zhen, Ming-Ming; Jiang, Feng; Shu, Chun-Ying; Jin, Chan; Yang, Yongji; Alhadlaq, Hisham A.; Wang, Chun-Ru

    2012-05-01

    A FAR over-expressed tumor targeting multifunctional imaging probe has been fabricated based on gadofulleride nanoplatform. The combination of highly efficient MRI contrast enhancement and sensitive fluorescence imaging along with the preferential uptake toward FAR tumor cells suggest that the obtained multifunctional imaging probe possesses complementary capabilities for anatomical resolution and detection sensitivity.A FAR over-expressed tumor targeting multifunctional imaging probe has been fabricated based on gadofulleride nanoplatform. The combination of highly efficient MRI contrast enhancement and sensitive fluorescence imaging along with the preferential uptake toward FAR tumor cells suggest that the obtained multifunctional imaging probe possesses complementary capabilities for anatomical resolution and detection sensitivity. Electronic supplementary information (ESI) available: Materials, instruments and methods, synthesis details, XPS characterization for estimation of average molecular formula, evaluation of conjugated FA and FITC ratio, zeta potential and fluorescent images. See DOI: 10.1039/c2nr30836c

  7. Residential Mechanical Precooling

    SciTech Connect

    German, a.; Hoeschele, M.

    2014-12-01

    This research conducted by the Alliance for Residential Building Innovation team evaluated mechanical air conditioner pre-cooling strategies in homes throughout the United States. EnergyPlus modeling evaluated two homes with different performance characteristics in seven climates. Results are applicable to new construction homes and most existing homes built in the last 10 years, as well as fairly efficient retrofitted homes.

  8. GREEN RETROFITTING RESIDENTIAL BUILDINGS

    EPA Science Inventory

    When compared with the rest of the world, the United States consumes a disproportionately large amount of energy and is a major source of greenhouse gases from fossil fuel combustion. As much as two thirds of U.S. electricity production is consumed by residential and commerci...

  9. Residential Solar Systems.

    ERIC Educational Resources Information Center

    Fulkerson, Dan

    This publication contains student and teacher instructional materials for a course in residential solar systems. The text is designed either as a basic solar course or as a supplement to extend student skills in areas such as architectural drafting, air conditioning and refrigeration, and plumbing. The materials are presented in four units…

  10. Evaluating Residential Institutions.

    ERIC Educational Resources Information Center

    Millham, Spencer

    Drawing on the research experience of the Dartington Social Research Unit, this paper discusses methods and perspectives used in evaluating English residential institutions for children. Work of the Dartington Social Research Unit has involved evaluating aspects of a wide range of institutions, from elite boarding schools to children's homes and…

  11. Nonmetropolitan Residential Segregation Revisited.

    ERIC Educational Resources Information Center

    Murdock, Steve H.; And Others

    1994-01-01

    Analysis of 1980 and 1990 Censuses of Population and Housing for Texas found overall black-white and Anglo-Hispanic residential segregation declined substantially. Nonmetropolitan counties were more segregated than metropolitan counties in both years, but growing nonmetro places showed the greatest segregation declines. Analyses controlling for…

  12. RESIDENTIAL VENTILATION STUDY

    EPA Science Inventory

    This project evaluated the effectiveness, first costs and operational costs of various types of residential ventilation systems in three different climates in the U.S. The Agency, through its Energy Star Program, recommends that builders construct homes that are energy efficient ...

  13. Residential Wiring. Second Edition.

    ERIC Educational Resources Information Center

    Taylor, Mark; And Others

    This guide is designed to assist teachers conducting a course to prepare students for entry-level employment in the residential wiring trade. Included in the guide are six instructional units and the following sections of information for teachers: guidelines in using the unit components; academic and workplace skills classifications and…

  14. Does multifunctionality matter to US farmers? Farmer motivations and conceptions of multifunctionality in dairy systems.

    PubMed

    Brummel, Rachel F; Nelson, Kristen C

    2014-12-15

    The concept of multifunctionality describes and promotes the multiple non-production benefits that emerge from agricultural systems. The notion of multifunctional agriculture was conceived in a European context and largely has been used in European policy arenas to promote and protect the non-production goods emerging from European agriculture. Thus scholars and policy-makers disagree about the relevance of multifunctionality for United States agricultural policy and US farmers. In this study, we explore lived expressions of multifunctional agriculture at the farm-level to examine the salience of the multifunctionality concept in the US. In particular, we investigate rotational grazing and confinement dairy farms in the eastern United States as case studies of multifunctional and productivist agriculture. We also analyze farmer motivations for transitioning from confinement dairy to rotational grazing systems. Through interviews with a range of dairy producers in Wisconsin, Pennsylvania, and New York, we found that farmers were motivated by multiple factors--including improved cow health and profitability--to transition to rotational grazing systems to achieve greater farm-level multifunctionality. Additionally, rotational grazing farmers attributed a broader range of production and non-production benefits to their farm practice than confinement dairy farmers. Further, rotational grazing dairy farmers described a system-level notion of multifunctionality based on the interdependence of multiple benefits across scales--from the farm to the national level--emerging from grazing operations. We find that the concept of multifunctionality could be expanded in the US to address the interdependence of benefits emerging from farming practices, as well as private benefits to farmers. We contend that understanding agricultural benefits as experienced by the farmer is an important contribution to enriching the multifunctionality concept in the US context, informing agri

  15. From "Weak" to "Strong" Multifunctionality: Conceptualising Farm-Level Multifunctional Transitional Pathways

    ERIC Educational Resources Information Center

    Wilson, Geoff A.

    2008-01-01

    Building on normative conceptualisations of multifunctionality as a decision-making spectrum bounded by productivist and non-productivist action and thought, this paper analyses farm-level multifunctional agricultural transitions. First, the paper suggests that it may be possible to categorise different farm types along the…

  16. Multifunctional nanorods for gene delivery

    NASA Astrophysics Data System (ADS)

    Salem, Aliasger K.; Searson, Peter C.; Leong, Kam W.

    2003-10-01

    The goal of gene therapy is to introduce foreign genes into somatic cells to supplement defective genes or provide additional biological functions, and can be achieved using either viral or synthetic non-viral delivery systems. Compared with viral vectors, synthetic gene-delivery systems, such as liposomes and polymers, offer several advantages including ease of production and reduced risk of cytotoxicity and immunogenicity, but their use has been limited by the relatively low transfection efficiency. This problem mainly stems from the difficulty in controlling their properties at the nanoscale. Synthetic inorganic gene carriers have received limited attention in the gene-therapy community, the only notable example being gold nanoparticles with surface-immobilized DNA applied to intradermal genetic immunization by particle bombardment. Here we present a non-viral gene-delivery system based on multisegment bimetallic nanorods that can simultaneously bind compacted DNA plasmids and targeting ligands in a spatially defined manner. This approach allows precise control of composition, size and multifunctionality of the gene-delivery system. Transfection experiments performed in vitro and in vivo provide promising results that suggest potential in genetic vaccination applications.

  17. Multifunctional self-assembled monolayers

    SciTech Connect

    Zawodzinski, T.; Bar, G.; Rubin, S.; Uribe, F.; Ferrais, J.

    1996-06-01

    This is the final report of at three year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The specific goals of this research project were threefold: to develop multifunctional self-assembled monolayers, to understand the role of monolayer structure on the functioning of such systems, and to apply this knowledge to the development of electrochemical enzyme sensors. An array of molecules that can be used to attach electrochemically active biomolecules to gold surfaces has been synthesized. Several members of a class of electroactive compounds have been characterized and the factors controlling surface modification are beginning to be characterized. Enzymes have been attached to self-assembled molecules arranged on the gold surface, a critical step toward the ultimate goal of this project. Several alternative enzyme attachment strategies to achieve robust enzyme- modified surfaces have been explored. Several means of juxtaposing enzymes and mediators, electroactive compounds through which the enzyme can exchange electrons with the electrode surface, have also been investigated. Finally, the development of sensitive biosensors based on films loaded with nanoscale-supported gold particles that have surface modified with the self-assembled enzyme and mediator have been explored.

  18. Guidelines for residential commissioning

    SciTech Connect

    Wray, Craig P.; Walker, Iain S.; Sherman, Max H.

    2003-01-31

    Currently, houses do not perform optimally or even as many codes and forecasts predict, largely because they are field assembled and there is no consistent process to identify problems or to correct them. Residential commissioning is a solution to this problem. This guide is the culmination of a 30-month project that began in September 1999. The ultimate objective of the project is to increase the number of houses that undergo commissioning, which will improve the quality, comfort, and safety of homes for California citizens. The project goal is to lay the groundwork for a residential commissioning industry in California focused on end-use energy and non-energy issues. As such, we intend this guide to be a beginning and not an end. Our intent is that the guide will lead to the programmatic integration of commissioning with other building industry processes, which in turn will provide more value to a single site visit for people such as home energy auditors and raters, home inspectors, and building performance contractors. Project work to support the development of this guide includes: a literature review and annotated bibliography, which facilitates access to 469 documents related to residential commissioning published over the past 20 years (Wray et al. 2000), an analysis of the potential benefits one can realistically expect from commissioning new and existing California houses (Matson et al. 2002), and an assessment of 107 diagnostic tools for evaluating residential commissioning metrics (Wray et al. 2002). In this guide, we describe the issues that non-experts should consider in developing a commissioning program to achieve the benefits we have identified. We do this by providing specific recommendations about: how to structure the commissioning process, which diagnostics to use, and how to use them to commission new and existing houses. Using examples, we also demonstrate the potential benefits of applying the recommended whole-house commissioning approach to

  19. Detailed residential electric determination

    SciTech Connect

    Not Available

    1984-06-01

    Data on residential loads has been collected from four residences in real time. The data, measured at 5-second intervals for 53 days of continuous operation, were statistically characterized. An algorithm was developed and incorporated into the modeling code SOLCEL. Performance simulations with SOLCEL using these data as well as previous data collected over longer time intervals indicate that no significant errors in system value are introduced through the use of long-term average data.

  20. Some Endpoint Results for β-Generalized Weak Contractive Multifunctions

    PubMed Central

    Alikhani, H.; Gopal, D.; Miandaragh, M. A.; Rezapour, Sh.; Shahzad, N.

    2013-01-01

    We introduce β-generalized weak contractive multifunctions and give some results about endpoints of the multifunctions. Also, we give some results about role of a point in the existence of endpoints. PMID:24348197

  1. Utilization management for residential programs.

    PubMed

    Kidd, Sean A; Styron, Thomas H; Carlson, Shelly; Hoge, Michael

    2004-07-01

    This paper reviews recent literature on utilization management (UM) in community-based supportive residential programs for people with behavioral disorders. Various approaches for facilitating placement and movement are discussed in the context of an effort to develop a residential UM process in New Haven, Connecticut. Recommendations are made for a residential UM process that may be applied to a range of service systems. It takes into account the methodological difficulties inherent in the development of generalizable decision tools. PMID:15478874

  2. Re-thinking residential mobility

    PubMed Central

    van Ham, Maarten; Findlay, Allan M.

    2015-01-01

    While researchers are increasingly re-conceptualizing international migration, far less attention has been devoted to re-thinking short-distance residential mobility and immobility. In this paper we harness the life course approach to propose a new conceptual framework for residential mobility research. We contend that residential mobility and immobility should be re-conceptualized as relational practices that link lives through time and space while connecting people to structural conditions. Re-thinking and re-assessing residential mobility by exploiting new developments in longitudinal analysis will allow geographers to understand, critique and address pressing societal challenges. PMID:27330243

  3. Multifunctional materials for bone cancer treatment

    PubMed Central

    Marques, Catarina; Ferreira, José MF; Andronescu, Ecaterina; Ficai, Denisa; Sonmez, Maria; Ficai, Anton

    2014-01-01

    The purpose of this review is to present the most recent findings in bone tissue engineering. Special attention is given to multifunctional materials based on collagen and collagen–hydroxyapatite composites used for skin and bone cancer treatments. The multi-functionality of these materials was obtained by adding to the base regenerative grafts proper components, such as ferrites (magnetite being the most important representative), cytostatics (cisplatin, carboplatin, vincristine, methotrexate, paclitaxel, doxorubicin), silver nanoparticles, antibiotics (anthracyclines, geldanamycin), and/or analgesics (ibuprofen, fentanyl). The suitability of complex systems for the intended applications was systematically analyzed. The developmental possibilities of multifunctional materials with regenerative and curative roles (antitumoral as well as pain management) in the field of skin and bone cancer treatment are discussed. It is worth mentioning that better materials are likely to be developed by combining conventional and unconventional experimental strategies. PMID:24920907

  4. Complex Multifunctional Polymer/Carbon-Nanotube Composites

    NASA Technical Reports Server (NTRS)

    Patel, Pritesh; Balasubramaniyam, Gobinath; Chen, Jian

    2009-01-01

    A methodology for developing complex multifunctional materials that consist of or contain polymer/carbon-nanotube composites has been conceived. As used here, "multifunctional" signifies having additional and/or enhanced physical properties that polymers or polymer-matrix composites would not ordinarily be expected to have. Such properties include useful amounts of electrical conductivity, increased thermal conductivity, and/or increased strength. In the present methodology, these properties are imparted to a given composite through the choice and processing of its polymeric and CNT constituents.

  5. Multifunctional Nucleic Acids for Tumor Cell Treatment

    PubMed Central

    Pofahl, Monika; Wengel, Jesper

    2014-01-01

    We report on a multifunctional nucleic acid, termed AptamiR, composed of an aptamer domain and an antimiR domain. This composition mediates cell specific delivery of antimiR molecules for silencing of endogenous micro RNA. The introduced multifunctional molecule preserves cell targeting, anti-proliferative and antimiR function in one 37-nucleotide nucleic acid molecule. It inhibits cancer cell growth and induces gene expression that is pathologically damped by an oncomir. These findings will have a strong impact on future developments regarding aptamer- and antimiR-related applications for tumor targeting and treatment. PMID:24494617

  6. Novel hybrid multifunctional magnetoelectric porous composite films

    NASA Astrophysics Data System (ADS)

    Martins, P.; Gonçalves, R.; Lopes, A. C.; Venkata Ramana, E.; Mendiratta, S. K.; Lanceros-Mendez, S.

    2015-12-01

    Novel multifunctional porous films have been developed by the integration of magnetic CoFe2O4 (CFO) nanoparticles into poly(vinylidene fluoride)-Trifuoroethylene (P(VDF-TrFE)), taking advantage of the synergies of the magnetostrictive filler and the piezoelectric polymer. The porous films show a piezoelectric response with an effective d33 coefficient of -22 pC/N-1, a maximum magnetization of 12 emu g-1 and a maximum magnetoelectric coefficient of 9 mV cm-1 Oe-1. In this way, a multifunctional membrane has been developed suitable for advanced applications ranging from biomedical to water treatment.

  7. ASHRAE and residential ventilation

    SciTech Connect

    Sherman, Max H.

    2003-10-01

    In the last quarter of a century, the western world has become increasingly aware of environmental threats to health and safety. During this period, people psychologically retreated away from outdoors hazards such as pesticides, smog, lead, oil spills, and dioxin to the seeming security of their homes. However, the indoor environment may not be healthier than the outdoor environment, as has become more apparent over the past few years with issues such as mold, formaldehyde, and sick-building syndrome. While the built human environment has changed substantially over the past 10,000 years, human biology has not; poor indoor air quality creates health risks and can be uncomfortable. The human race has found, over time, that it is essential to manage the indoor environments of their homes. ASHRAE has long been in the business of ventilation, but most of the focus of that effort has been in the area of commercial and institutional buildings. Residential ventilation was traditionally not a major concern because it was felt that, between operable windows and envelope leakage, people were getting enough outside air in their homes. In the quarter of a century since the first oil shock, houses have gotten much more energy efficient. At the same time, the kinds of materials and functions in houses changed in character in response to people's needs. People became more environmentally conscious and aware not only about the resources they were consuming but about the environment in which they lived. All of these factors contributed to an increasing level of public concern about residential indoor air quality and ventilation. Where once there was an easy feeling about the residential indoor environment, there is now a desire to define levels of acceptability and performance. Many institutions--both public and private--have interests in Indoor Air Quality (IAQ), but ASHRAE, as the professional society that has had ventilation as part of its mission for over 100 years, is the

  8. Residential Segregation and School Integration.

    ERIC Educational Resources Information Center

    Rivkin, Steven G.

    1994-01-01

    Asserts that school districts' efforts to integrate schools have failed to ameliorate the racial isolation of black students. Finds that schools remain segregated primarily because of continued residential segregation and that school integration efforts have had little long-term effect on residential segregation. (CFR)

  9. The Dimensions of Residential Segregation.

    ERIC Educational Resources Information Center

    Massey, Douglas S.; Denton, Nancy A.

    1988-01-01

    Evaluates 20 potential indicators of residential segregation using census data on Hispanics, Blacks, Asians, and non-Hispanic Whites in 60 U.S. metropolitan areas. Factor-analyzes the results to select a single best indicator for each of five dimensions of residential segregation. Contains 69 references and 22 statistical formulas. (SV)

  10. Residential fuel quality

    SciTech Connect

    Santa, T.

    1997-09-01

    This report details progress made in improving the performance of No. 2 heating oil in residential applications. Previous research in this area is documented in papers published in the Brookhaven Oil Heat Technology Conference Proceedings in 1993, 1994 and 1996. By way of review we have investigated a number of variables in the search for improved fuel system performance. These include the effect of various additives designed to address stability, dispersion, biotics, corrosion and reaction with metals. We have also investigated delivery methods, filtration, piping arrangements and the influence of storage tank size and location. As a result of this work Santa Fuel Inc. in conjunction with Mobile Oil Corporation have identified an additive package which shows strong evidence of dramatically reducing the occurrence of fuel system failures in residential oil burners. In a broad market roll-out of the additized product we have experienced a 29% reduction in fuel related service calls when comparing the 5 months ending January 1997 to the same period ending January 1996.

  11. National Residential Efficiency Measures Database

    DOE Data Explorer

    The National Residential Efficiency Measures Database is a publicly available, centralized resource of residential building retrofit measures and costs for the U.S. building industry. With support from the U.S. Department of Energy, NREL developed this tool to help users determine the most cost-effective retrofit measures for improving energy efficiency of existing homes. Software developers who require residential retrofit performance and cost data for applications that evaluate residential efficiency measures are the primary audience for this database. In addition, home performance contractors and manufacturers of residential materials and equipment may find this information useful. The database offers the following types of retrofit measures: 1) Appliances, 2) Domestic Hot Water, 3) Enclosure, 4) Heating, Ventilating, and Air Conditioning (HVAC), 5) Lighting, 6) Miscellaneous.

  12. Several scales of biodiversity affect ecosystem multifunctionality.

    PubMed

    Pasari, Jae R; Levi, Taal; Zavaleta, Erika S; Tilman, David

    2013-06-18

    Society values landscapes that reliably provide many ecosystem functions. As the study of ecosystem functioning expands to include more locations, time spans, and functions, the functional importance of individual species is becoming more apparent. However, the functional importance of individual species does not necessarily translate to the functional importance of biodiversity measured in whole communities of interacting species. Furthermore, ecological diversity at scales larger than neighborhood species richness could also influence the provision of multiple functions over extended time scales. We created experimental landscapes based on whole communities from the world's longest running biodiversity-functioning field experiment to investigate how local species richness (α diversity), distinctness among communities (β diversity), and larger scale species richness (γ diversity) affected eight ecosystem functions over 10 y. Using both threshold-based and unique multifunctionality metrics, we found that α diversity had strong positive effects on most individual functions and multifunctionality, and that positive effects of β and γ diversity emerged only when multiple functions were considered simultaneously. Higher β diversity also reduced the variability in multifunctionality. Thus, in addition to conserving important species, maintaining ecosystem multifunctionality will require diverse landscape mosaics of diverse communities. PMID:23733963

  13. Brain and language: evidence for neural multifunctionality.

    PubMed

    Cahana-Amitay, Dalia; Albert, Martin L

    2014-01-01

    This review paper presents converging evidence from studies of brain damage and longitudinal studies of language in aging which supports the following thesis: the neural basis of language can best be understood by the concept of neural multifunctionality. In this paper the term "neural multifunctionality" refers to incorporation of nonlinguistic functions into language models of the intact brain, reflecting a multifunctional perspective whereby a constant and dynamic interaction exists among neural networks subserving cognitive, affective, and praxic functions with neural networks specialized for lexical retrieval, sentence comprehension, and discourse processing, giving rise to language as we know it. By way of example, we consider effects of executive system functions on aspects of semantic processing among persons with and without aphasia, as well as the interaction of executive and language functions among older adults. We conclude by indicating how this multifunctional view of brain-language relations extends to the realm of language recovery from aphasia, where evidence of the influence of nonlinguistic factors on the reshaping of neural circuitry for aphasia rehabilitation is clearly emerging. PMID:25009368

  14. Multifunctional, High-Temperature Nanocomposites

    NASA Technical Reports Server (NTRS)

    Connell, John W.; Smith, Joseph G.; Siochi, Emilie J.; Working, Dennis C.; Criss, Jim M.; Watson, Kent A.; Delozier, Donavon M.; Ghose, Sayata

    2007-01-01

    In experiments conducted as part of a continuing effort to incorporate multifunctionality into advanced composite materials, blends of multi-walled carbon nanotubes and a resin denoted gPETI-330 h (wherein gPETI h is an abbreviation for gphenylethynyl-terminated imide h) were prepared, characterized, and fabricated into moldings. PETI-330 was selected as the matrix resin in these experiments because of its low melt viscosity (<10 poise at a temperature of 280 C), excellent melt stability (lifetime >2 hours at 280 C), and high temperature performance (>1,000 hours at 288 C). The multi-walled carbon nanotubes (MWCNTs), obtained from the University of Kentucky, were selected because of their electrical and thermal conductivity and their small diameters. The purpose of these experiments was to determine the combination of thermal, electrical, and mechanical properties achievable while still maintaining melt processability. The PETI-330/MWCNT mixtures were prepared at concentrations ranging from 3 to 25 weight-percent of MWCNTs by dry mixing of the constituents in a ball mill using zirconia beads. The resulting powders were characterized for degree of mixing and thermal and rheological properties. The neat resin was found to have melt viscosity between 5 and 10 poise. At 280 C and a fixed strain rate, the viscosity was found to increase with time. At this temperature, the phenylethynyl groups do not readily react and so no significant curing of the resin occurred. For MWCNT-filled samples, melt viscosity was reasonably steady at 280 C and was greater in samples containing greater proportions of MWCNTs. The melt viscosity for 20 weightpercent of MWCNTs was found to be .28,000 poise, which is lower than the initial estimated allowable maximum value of 60,000 poise for injection molding. Hence, MWCNT loadings of as much as 20 percent were deemed to be suitable compositions for scale-up. High-resolution scanning electron microscopy (HRSEM) showed the MWCNTs to be well

  15. Magnetically Attached Multifunction Maintenance Rover

    NASA Technical Reports Server (NTRS)

    Bar-Cohen, Yoseph; Joffe, Benjamin

    2005-01-01

    A versatile mobile telerobot, denoted the magnetically attached multifunction maintenance rover (MAGMER), has been proposed for use in the inspection and maintenance of the surfaces of ships, tanks containing petrochemicals, and other large ferromagnetic structures. As its name suggests, this robot would utilize magnetic attraction to adhere to a structure. As it moved along the surface of the structure, the MAGMER would perform tasks that could include close-up visual inspection by use of video cameras, various sensors, and/or removal of paint by water-jet blasting, laser heating, or induction heating. The water-jet nozzles would be mounted coaxially within compressed-air-powered venturi nozzles that would collect the paint debris dislodged by the jets. The MAGMER would be deployed, powered, and controlled from a truck, to which it would be connected by hoses for water, compressed air, and collection of debris and by cables for electric power and communication (see Figure 1). The operation of the MAGMER on a typical large structure would necessitate the use of long cables and hoses, which can be heavy. To reduce the load of the hoses and cables on the MAGMER and thereby ensure its ability to adhere to vertical and overhanging surfaces, the hoses and cables would be paid out through telescopic booms that would be parts of a MAGMER support system. The MAGMER would move by use of four motorized, steerable wheels, each of which would be mounted in an assembly that would include permanent magnets and four pole pieces (see Figure 2). The wheels would protrude from between the pole pieces by only about 3 mm, so that the gap between the pole pieces and the ferromagnetic surface would be just large enough to permit motion along the surface but not so large as to reduce the magnetic attraction excessively. In addition to the wheel assemblies, the MAGMER would include magnetic adherence enhancement fixtures, which would comprise arrays of permanent magnets and pole pieces

  16. Integrated residential photovoltaic array development

    NASA Technical Reports Server (NTRS)

    Shepard, N. F., Jr.

    1981-01-01

    An advanced, universally-mountable, integrated residential photovoltaic array concept was defined based upon an in-depth formulation and evaluation of three candidate approaches which were synthesized from existing or proposed residential array concepts. The impact of module circuitry and process sequence is considered and technology gaps and performance drivers associated with residential photovoltaic array concepts are identified. The actual learning experience gained from the comparison of the problem areas of the hexagonal shingle design with the rectangular module design led to what is considered an advanced array concept. Building the laboratory mockup provided actual experience and the opportunity to uncover additional technology gaps.

  17. Integrated residential photovoltaic array development

    NASA Astrophysics Data System (ADS)

    Shepard, N. F., Jr.

    1981-12-01

    An advanced, universally-mountable, integrated residential photovoltaic array concept was defined based upon an in-depth formulation and evaluation of three candidate approaches which were synthesized from existing or proposed residential array concepts. The impact of module circuitry and process sequence is considered and technology gaps and performance drivers associated with residential photovoltaic array concepts are identified. The actual learning experience gained from the comparison of the problem areas of the hexagonal shingle design with the rectangular module design led to what is considered an advanced array concept. Building the laboratory mockup provided actual experience and the opportunity to uncover additional technology gaps.

  18. Review of Residential Ventilation Technologies

    SciTech Connect

    Armin Rudd

    2005-08-30

    This paper reviews current and potential ventilation technologies for residential buildings, including a variety of mechanical systems, natural ventilation, and passive ventilation. with particular emphasis on North American climates and construction.

  19. Residential Demand Module - NEMS Documentation

    EIA Publications

    2014-01-01

    Model Documentation - Documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Residential Sector Demand Module. The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, and FORTRAN source code.

  20. School Desegregation and Residential Segregation.

    ERIC Educational Resources Information Center

    Billingsley, Andrew; And Others

    1979-01-01

    This statement on school and residential segregation, signed by 38 educators and social scientists, was prepared for attorneys connected with litigation concerning the Dayton and Columbus school systems. (RLV)

  1. MULTIFUNCTIONAL AND STIMULI-SENSITIVE PHARMACEUTICAL NANOCARRIERS

    PubMed Central

    Torchilin, Vladimir

    2011-01-01

    Currently used pharmaceutical nanocarriers, such as liposomes, micelles, and polymeric nanoparticles, demonstrate a broad variety of useful properties, such as longevity in the body; specific targeting to certain disease sites; enhanced intracellular penetration; contrast properties allowing for direct carrier visualization in vivo; stimili-sensitivity, and others. Some of those pharmaceutical carriers have already made their way into clinic, while others are still under preclinical development. In certain cases, the pharmaceutical nanocarriers combine several of the listed properties. Long-circulating immunoliposomes capable of prolonged residence in the blood and specific target recognition represent one of examples of this kind. The engineering of multifunctional pharmaceutical nanocarriers combining several useful properties in one particle can significantly enhance the efficacy of many therapeutic and diagnostic protocols. This paper considers the current status and possible future directions in the emerging area of multifunctional nanocarriers with primary attention on the combination of such properties as longevity, targetability, intracellular penetration, contrast loading, and stimuli sensitivity. PMID:18977297

  2. The Coronavirus Nucleocapsid Is a Multifunctional Protein

    PubMed Central

    McBride, Ruth; van Zyl, Marjorie; Fielding, Burtram C.

    2014-01-01

    The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly. Recent studies have confirmed that N is a multifunctional protein. The aim of this review is to highlight the properties and functions of the N protein, with specific reference to (i) the topology; (ii) the intracellular localization and (iii) the functions of the protein. PMID:25105276

  3. Holmium laser for multifunctional use in urology

    NASA Astrophysics Data System (ADS)

    Watson, Graham M.; Shroff, Sunil; Thomas, Robert; Kellett, Michael

    1994-05-01

    The holmium laser pulsed at 350 microsecond cuts tissue and fragments calculi. It has been assessed for minimally invasive urological intervention. It is useful for partly excising and partly coagulating tumors, incising strictures and the obstructed PUJ. It partly drill and partly fragments urinary calculi however hard. Other lasers are more effective at any one particular application, but this laser is a useful compromise as a multifunctional device.

  4. Approach to multifunction radar tracker design

    NASA Astrophysics Data System (ADS)

    Casar Corredera, Jose R.; Harvey, Denis H.

    A new approach is presented to select optimally both the energy of the tracking waveforms and the track sampling rates which jointly minimize occupancy and satisfy angular accuracy requirements for a multifunction radar. The design process is illustrated for a particular system. The results suggest that the radar's energy should be managed as a function of target size and range so as to obtain an SNR as close as possible to its optimal value.

  5. Multiscale/Multifunctional Probabilistic Composite Fatigue

    NASA Technical Reports Server (NTRS)

    Chamis, Christos C.

    2010-01-01

    A multilevel (multiscale/multifunctional) evaluation is demonstrated by applying it to three different sample problems. These problems include the probabilistic evaluation of a space shuttle main engine blade, an engine rotor and an aircraft wing. The results demonstrate that the blade will fail at the highest probability path, the engine two-stage rotor will fail by fracture at the rim and the aircraft wing will fail at 109 fatigue cycles with a probability of 0.9967.

  6. Utility competition and residential customers

    SciTech Connect

    Studness, C.M.

    1994-11-01

    Residential customers have found themselves either ignored or ill-used by the major participants in the struggle over utility competition. No group is seeking to secure them the benefits of competition, and those who oppose competition have curried their favor by conjuring up misleading horror stories about how competition would harm them. Yet residential customers ultimately stand to gain as much from competition as larger customers.

  7. Thick-walled carbon composite multifunctional structures

    NASA Astrophysics Data System (ADS)

    Haake, John M.; Jacobs, Jack H.; McIlroy, Bruce E.

    1997-06-01

    Satellite programs are moving in the direction of smaller and lighter structures. Technological advances have permitted more sophisticated equipment to be consolidated into compact spaces. Micro-satellites, between 10 and 100 kg, will incorporate micro-electric devices into the lay-up of the satellite structure. These structures will be designed to carry load, provide thermal control, enhance damping, and include integrated passive electronics. These multifunctional structures offer lighter weight, reduced volume, and a 'smarter' overall package for incorporation of sensors, electronics, fiber optics, powered appendages or active components. McDonnell Douglas Corporation (MDC) has applied technology from the synthesis and processing of intelligent cost effective structures (SPICES) and independent research and development (IRAD) programs to the modular instrument support system (MISS) for multifunctional space structures and micro-satellites. The SPICES program was funded by the Defense Advanced Research Projects Agency (DARPA) to develop affordable manufacturing processes for smart materials to be used in vibration control, and the MISS program was funded by NASA-Langley. The MISS program was conceived to develop concepts and techniques to make connections between different multifunctional structures. MDA fabricated a trapezoidal carbon composite structure out of IM7/977-3 tape prepreg. Flex circuits, thermal and optical conduits were embedded to realize a utility modular connector. These provide electrical, thermal, optical and mechanical connections between micro- satellite components. A quick disconnect mount was also developed to accommodate a variety of devices such as solar arrays, power sources, thermal transfer and vibration control modules.

  8. A Multifunctional Coating for Autonomous Corrosion Control

    NASA Technical Reports Server (NTRS)

    Calle, Luz M.; Li, Wenyan; Buhrow, Jerry W.; Jolley, Scott t.

    2011-01-01

    Nearly all metals and their alloys are subject to corrosion that causes them to lose their structural integrity or other critical functionality. Protective coatings are the most commonly used method of corrosion control. However, progressively stricter environmental regulations have resulted in the ban of many commercially available corrosion protective coatings due to the harmful effects of their solvents or corrosion inhibitors. This work concerns the development of a multifunctional smart coating for the autonomous control of corrosion. This coating is being developed to have the inherent ability to detect the chemical changes associated with the onset of corrosion and respond autonomously to indicate it and control it. The multi-functionality of the coating is based on microencapsulation technology specifically designed for corrosion control applications. This design has, in addition to all the advantages of existing microcapsulation designs, the corrosion controlled release function that triggers the delivery of corrosion indicators and inhibitors on demand, only when and where needed. Microencapsulation of self-healing agents for autonomous repair of mechanical damage to the coating is also being pursued. Corrosion indicators, corrosion inhibitors, as well as self-healing agents, have been encapsulated and dispersed into several paint systems to test the corrosion detection, inhibition, and self-healing properties of the coating. Key words: Corrosion, coating, autonomous corrosion control, corrosion indication, corrosion inhibition, self-healing coating, smart coating, multifunctional coating, microencapsulation.

  9. Biomimetic multifunctional surfaces inspired from animals.

    PubMed

    Han, Zhiwu; Mu, Zhengzhi; Yin, Wei; Li, Wen; Niu, Shichao; Zhang, Junqiu; Ren, Luquan

    2016-08-01

    Over millions of years, animals have evolved to a higher intelligent level for their environment. A large number of diverse surface structures on their bodies have been formed to adapt to the extremely harsh environment. Just like the structural diversity existed in plants, the same also applies true in animals. Firstly, this article provides an overview and discussion of the most common functional surface structures inspired from animals, such as drag reduction, noise reduction, anti-adhesion, anti-wear, anti-erosion, anti-fog, water capture, and optical surfaces. Then, some typical characteristics of morphologies, structures, and materials of the animal multifunctional surfaces were discussed. The adaptation of these surfaces to environmental conditions was also analyzed. It mainly focuses on the relationship between their surface functions and their surface structural characteristics. Afterwards, the multifunctional mechanisms or principles of these surfaces were discussed. Models of these structures were provided for the development of structure materials and machinery surfaces. At last, fabrication techniques and existing or potential technical applications inspired from biomimetic multifunctional surfaces in animals were also discussed. The application prospects of the biomimetic functional surfaces are very broad, such as civil field of self-cleaning textile fabrics and non-stick pots, ocean field of oil-water separation, sports field of swimming suits, space development field of lens arrays. PMID:27085632

  10. Residential Transactive Control Demonstration

    SciTech Connect

    Widergren, Steven E.; Fuller, Jason C.; Marinovici, Maria C.; Somani, Abhishek

    2014-02-19

    Arguably the most exciting aspect of the smart grid vision is the full participation of end-use resources with all forms of generation and energy storage in the reliable and efficient operation of an electric power system. Engaging all of these resources in a collaborative manner that respects the objectives of each resource, is sensitive to the system and local constraints of electricity flow, and scales to the large number of devices and systems participating is a grand challenge. Distributed decision-making system approaches have been presented and experimentation is underway. This paper reports on the preliminary findings of a residential demand response demonstration that uses the bidding transactions of supply and end-use air conditioning resources communicating with a real-time, 5 minute market to balance the various needs of the participants on a distribution feeder. The nature of the demonstration, the value streams being explored, and the operational scenarios implemented to characterize the system response are summarized along with preliminary findings.

  11. Energy Simulator Residential Buildings

    Energy Science and Technology Software Center (ESTSC)

    1992-02-24

    SERI-RES performs thermal energy analysis of residential or small commercial buildings and has the capability of modeling passive solar equipment such as rock beds, trombe walls, and phase change material. The analysis is accomplished by simulation. A thermal model of the building is created by the user and translated into mathematical form by the program. The mathematical equations are solved repeatedly at time intervals of one hour or less for the period of simulation. Themore » mathematical representation of the building is a thermal network with nonlinear, temperature-dependent controls. A combination of forward finite differences, Jacobian iteration, and constrained optimization techniques is used to obtain a solution. An auxiliary interactive editing program, EDITOR, is included for creating building descriptions. EDITOR checks the validity of the input data and also provides facilities for storing and referencing several types of building description files. Some of the data files used by SERI-RES need to be implemented as direct-access files. Programs are included to convert sequential files to direct-access files and vice versa.« less

  12. Development of thermoplastic coated multifunctional transmission elements

    NASA Astrophysics Data System (ADS)

    Golaz, B.; Michaud, V.; de Oliveira, R.; Månson, J.-A. E.

    2012-04-01

    We report on key challenges of the development of steel cords reinforced thermoplastic elastomer composites with smart functionalities: adhesion tailoring for a durable mechanical load transfer through steel cords or other transmission elements by the use of surface treatments and primers, and integrated distributed temperature and strain sensing by the use of embedded fiber optic sensors. Traditional surface treatments including silane coupling agent were outperformed in processing time, adhesion and durability by a fast-curing coupling method using a UV-curable primer; and the integrated distributed temperature and strain sensing capability was demonstrated. The practical applications of the resulting multifunctional transmission element are then discussed in light of these results.

  13. Ultrastrong, Stiff and Multifunctional Carbon Nanotube Composites

    SciTech Connect

    Wang, Xin; Yong, Zhenzhong; Li, Qingwen; Bradford, Philip D.; Liu, Wei; Tucker, Dennis S.; Cai, Wei; Wang, Hsin; Yuan, Fuh-Gwo; Zhu, Yuntian

    2012-01-01

    Carbon nanotubes (CNTs) are an order of magnitude stronger than any current engineering fiber. However, for the past two decades it has been a challenge to utilize their reinforcement potential in composites. Here we report CNT composites with unprecedented multifunctionalities, including record high strength (3.8 GPa), Young s modulus (293 GPa), electrical conductivity (1230 S cm-1) and thermal conductivity (41 W m-1 K-1). These superior properties are derived from the long length, high volume fraction, good alignment and reduced waviness of the CNTs, which were produced by a novel processing approach that can be easily scaled up for industrial production.

  14. Multifunctional epitaxial systems on silicon substrates

    NASA Astrophysics Data System (ADS)

    Singamaneni, Srinivasa Rao; Prater, John Thomas; Narayan, Jagdish

    2016-09-01

    Multifunctional heterostructures can exhibit a wide range of functional properties, including colossal magneto-resistance, magnetocaloric, and multiferroic behavior, and can display interesting physical phenomena including spin and charge ordering and strong spin-orbit coupling. However, putting this functionality to work remains a challenge. To date, most of the work reported in the literature has dealt with heterostructures deposited onto closely lattice matched insulating substrates such as DyScO3, SrTiO3 (STO), or STO buffered Si(100) using concepts of lattice matching epitaxy (LME). However, strain in heterostructures grown by LME is typically not fully relaxed and the layers contain detrimental defects such as threading dislocations that can significantly degrade the physical properties of the films and adversely affect the device characteristics. In addition, most of the substrates are incompatible with existing CMOS-based technology, where Si (100) substrates dominate. This review discusses recent advances in the integration of multifunctional oxide and non-oxide materials onto silicon substrates. An alternative thin film growth approach, called "domain matching epitaxy," is presented which identifies approaches for minimizing lattice strain and unwanted defects in large misfit systems (7%-25% and higher). This approach broadly allows for the integration of multifunctional materials onto silicon substrates, such that sensing, computation, and response functions can be combined to produce next generation "smart" devices. In general, pulsed laser deposition has been used to epitaxially grow these materials, although the concepts developed here can be extended to other deposition techniques, as well. It will be shown that TiN and yttria-stabilized zirconia template layers provide promising platforms for the integration of new functionality into silicon-based computer chips. This review paper reports on a number of thin-film heterostructure systems that span a

  15. 5-GHz fully differential multifunctional circuit

    NASA Astrophysics Data System (ADS)

    Plessas, F.; Tsitouras, A.; Kalivas, G.

    2012-09-01

    This letter presents a multifunctional circuit realising the functions of oscillation, frequency multiplication and frequency division at 5-GHz. A theoretical and experimental description of the circuit is given. The injection signal, which is used to stabilise the oscillation, is at a sub- or super-harmonic of the oscillation frequency having a power level as low as -30 dBm. Calculations and measurements of the phase noise are reported which indicate a phase noise improvement. The implementation of the circuit exhibits a phase noise of -110 dBc/Hz at 100 KHz offset whereas the improvement depends on the relative noise of the injected signal.

  16. Multifunctional hybrid nanogels for theranostic applications.

    PubMed

    Sierra-Martin, B; Fernandez-Barbero, A

    2015-11-14

    This paper reviews a wide set of theranostic applications based on the special properties associated with composite nanogels. The nanogels presented here are mostly hybridized with quantum dots, magnetic nanoparticles, and plasmonic metal noble nanoparticles. These inorganic components confer nanogels multifunctional properties that extend their applications from drug delivery systems to diagnosis and therapy. Nanogels can also be surface functionalized with specific ligands to achieve targeted therapy and reduce toxicity. This versatility makes hybrid nanogels very promising agents for imaging, diagnosis and treatment of cancer and other diseases. PMID:26371991

  17. Requirements for a multifunctional code architecture

    SciTech Connect

    Tiihonen, O.; Juslin, K.

    1997-07-01

    The present paper studies a set of requirements for a multifunctional simulation software architecture in the light of experiences gained in developing and using the APROS simulation environment. The huge steps taken in the development of computer hardware and software during the last ten years are changing the status of the traditional nuclear safety analysis software. The affordable computing power on the safety analysts table by far exceeds the possibilities offered to him/her ten years ago. At the same time the features of everyday office software tend to set standards to the way the input data and calculational results are managed.

  18. Plant species richness and ecosystem multifunctionality in global drylands

    USGS Publications Warehouse

    Maestre, Fernando T.; Quero, Jose L.; Gotelli, Nicholas J.; Escudero, Adrian; Ochoa, Victoria; Delgado-Baquerizo, Manuel; Garcia-Gomez, Miguel; Bowker, Matthew A.; Soliveres, Santiago; Escolar, Cristina; Garcia-Palacios, Pablo; Berdugo, Miguel; Valencia, Enrique; Gozalo, Beatriz; Gallardo, Antonio; Aguilera, Lorgio; Arredondo, Tulio; Blones, Julio; Boeken, Bertrand; Bran, Donaldo; Conceicao, Abel A.; Cabrera, Omar; Chaieb, Mohamed; Derak, Mchich; Eldridge, David J.; Espinosa, Carlos I.; Florentino, Adriana; Gaitan, Juan; Gatica, M. Gabriel; Ghiloufi, Wahida; Gomez-Gonzalez, Susana; Gutie, Julio R.; Hernandez, Rosa M.; Huang, Xuewen; Huber-Sannwald, Elisabeth; Jankju, Mohammad; Miriti, Maria; Monerris, Jorge; Mau, Rebecca L.; Morici, Ernesto; Naseri, Kamal; Ospina, Abelardo; Polo, Vicente; Prina, Anibal; Pucheta, Eduardo; Ramirez-Collantes, David A.; Romao, Roberto; Tighe, Matthew; Torres-Diaz, Cristian; Val, James; Veiga, Jose P.; Wang, Deli; Zaady, Eli

    2012-01-01

    Experiments suggest that biodiversity enhances the ability of ecosystems to maintain multiple functions, such as carbon storage, productivity, and the buildup of nutrient pools (multifunctionality). However, the relationship between biodiversity and multifunctionality has never been assessed globally in natural ecosystems. We report here on a global empirical study relating plant species richness and abiotic factors to multifunctionality in drylands, which collectively cover 41% of Earth's land surface and support over 38% of the human population. Multifunctionality was positively and significantly related to species richness. The best-fitting models accounted for over 55% of the variation in multifunctionality and always included species richness as a predictor variable. Our results suggest that the preservation of plant biodiversity is crucial to buffer negative effects of climate change and desertification in drylands.

  19. Plant species richness and ecosystem multifunctionality in global drylands

    PubMed Central

    Maestre, Fernando T.; Quero, José L.; Gotelli, Nicholas J.; Escudero, Adriá; Ochoa, Victoria; Delgado-Baquerizo, Manuel; García-Gómez, Miguel; Bowker, Matthew A.; Soliveres, Santiago; Escolar, Cristina; García-Palacios, Pablo; Berdugo, Miguel; Valencia, Enrique; Gozalo, Beatriz; Gallardo, Antonio; Aguilera, Lorgio; Arredondo, Tulio; Blones, Julio; Boeken, Bertrand; Bran, Donaldo; Conceição, Abel A.; Cabrera, Omar; Chaieb, Mohamed; Derak, Mchich; Eldridge, David J.; Espinosa, Carlos I.; Florentino, Adriana; Gaitán, Juan; Gatica, M. Gabriel; Ghiloufi, Wahida; Gómez-González, Susana; Gutiérrez, Julio R.; Hernández, Rosa M.; Huang, Xuewen; Huber-Sannwald, Elisabeth; Jankju, Mohammad; Miriti, Maria; Monerris, Jorge; Mau, Rebecca L.; Morici, Ernesto; Naseri, Kamal; Ospina, Abelardo; Polo, Vicente; Prina, Aníbal; Pucheta, Eduardo; Ramírez-Collantes, David A.; Romão, Roberto; Tighe, Matthew; Torres-Díaz, Cristian; Val, James; Veiga, José P.; Wang, Deli; Zaady, Eli

    2013-01-01

    Experiments suggest that biodiversity enhances the ability of ecosystems to maintain multiple functions, such as carbon storage, productivity, and buildup of nutrient pools (multifunctionality). However, the relationship between biodiversity and multifunctionality has never been assessed globally in natural ecosystems. We report on the first global empirical study relating plant species richness and abiotic factors to multifunctionality in drylands, which collectively cover 41% of Earth’s land surface and support over 38% of the human population. Multifunctionality was positively and significantly related to species richness. The best-fitting models accounted for over 55% of the variation in multifunctionality, and always included species richness as a predictor variable. Our results suggest that preservation of plant biodiversity is crucial to buffer negative effects of climate change and desertification in drylands. PMID:22246775

  20. Extreme multifunctional proteins identified from a human protein interaction network

    PubMed Central

    Chapple, Charles E.; Robisson, Benoit; Spinelli, Lionel; Guien, Céline; Becker, Emmanuelle; Brun, Christine

    2015-01-01

    Moonlighting proteins are a subclass of multifunctional proteins whose functions are unrelated. Although they may play important roles in cells, there has been no large-scale method to identify them, nor any effort to characterize them as a group. Here, we propose the first method for the identification of ‘extreme multifunctional' proteins from an interactome as a first step to characterize moonlighting proteins. By combining network topological information with protein annotations, we identify 430 extreme multifunctional proteins (3% of the human interactome). We show that the candidates form a distinct sub-group of proteins, characterized by specific features, which form a signature of extreme multifunctionality. Overall, extreme multifunctional proteins are enriched in linear motifs and less intrinsically disordered than network hubs. We also provide MoonDB, a database containing information on all the candidates identified in the analysis and a set of manually curated human moonlighting proteins. PMID:26054620

  1. Residential-appliance load characteristics

    NASA Astrophysics Data System (ADS)

    Kohler, J.

    1982-04-01

    The performance of residential photovoltaic systems in combination with energy efficient appliances is examined. The load characteristics are presented for several types of major residential appliances. Load characteristics consist of the average energy use of each appliance, the power demand while the appliance is operating, and a typical use schedule. Potential energy conserving features are investigated for each appliance and used to identify a best available model and maximum feasible energy efficient appliance. Load characteristics of these energy conserving designs are then compared with the load characteristics of a standard model. The feasibility of converting appliances to dc power for use with photovoltaic systems is also discussed.

  2. 10 CFR 429.18 - Residential furnaces.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Residential furnaces. 429.18 Section 429.18 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.18 Residential furnaces. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to residential furnaces;...

  3. 10 CFR 429.18 - Residential furnaces.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Residential furnaces. 429.18 Section 429.18 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.18 Residential furnaces. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to residential furnaces;...

  4. 10 CFR 429.18 - Residential furnaces.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Residential furnaces. 429.18 Section 429.18 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.18 Residential furnaces. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to residential furnaces;...

  5. 34 CFR 300.104 - Residential placement

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Residential placement 300.104 Section 300.104 Education... DISABILITIES State Eligibility Other Fape Requirements § 300.104 Residential placement If placement in a public or private residential program is necessary to provide special education and related services to...

  6. 34 CFR 300.104 - Residential placement

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Residential placement 300.104 Section 300.104 Education... DISABILITIES State Eligibility Other Fape Requirements § 300.104 Residential placement If placement in a public or private residential program is necessary to provide special education and related services to...

  7. Characteristics of Owners of Residential Care Facilities.

    ERIC Educational Resources Information Center

    Horgan, Dianne D.; And Others

    Although researchers have investigated quality and cost of residential care, little is known about the people who own and manage residential care facilities. In an attempt to find out more about these managers, members of the National Association of Residential Care Facilities (NARCF) were surveyed. Members (N=175) responded to questionnaires…

  8. Faster Evolution of More Multifunctional Logic Circuits

    NASA Technical Reports Server (NTRS)

    Stoica, Adrian; Zebulum, Ricardo

    2005-01-01

    A modification in a method of automated evolutionary synthesis of voltage-controlled multifunctional logic circuits makes it possible to synthesize more circuits in less time. Prior to the modification, the computations for synthesizing a four-function logic circuit by this method took about 10 hours. Using the method as modified, it is possible to synthesize a six-function circuit in less than half an hour. The concepts of automated evolutionary synthesis and voltage-controlled multifunctional logic circuits were described in a number of prior NASA Tech Briefs articles. To recapitulate: A circuit is designed to perform one of several different logic functions, depending on the value of an applied control voltage. The circuit design is synthesized following an automated evolutionary approach that is so named because it is modeled partly after the repetitive trial-and-error process of biological evolution. In this process, random populations of integer strings that encode electronic circuits play a role analogous to that of chromosomes. An evolved circuit is tested by computational simulation (prior to testing in real hardware to verify a final design). Then, in a fitness-evaluation step, responses of the circuit are compared with specifications of target responses and circuits are ranked according to how close they come to satisfying specifications. The results of the evaluation provide guidance for refining designs through further iteration.

  9. Identification of multifunctional peptides from human milk.

    PubMed

    Mandal, Santi M; Bharti, Rashmi; Porto, William F; Gauri, Samiran S; Mandal, Mahitosh; Franco, Octavio L; Ghosh, Ananta K

    2014-06-01

    Pharmaceutical industries have renewed interest in screening multifunctional bioactive peptides as a marketable product in health care applications. In this context, several animal and plant peptides with potential bioactivity have been reported. Milk proteins and peptides have received much attention as a source of health-enhancing components to be incorporated into nutraceuticals and functional foods. By using this source, 24 peptides have been fractionated and purified from human milk using RP-HPLC. Multifunctional roles including antimicrobial, antioxidant and growth stimulating activity have been evaluated in all 24 fractions. Nevertheless, only four fractions show multiple combined activities among them. Using a proteomic approach, two of these four peptides have been identified as lactoferrin derived peptide and kappa casein short chain peptide. Lactoferrin derived peptide (f8) is arginine-rich and kappa casein derived (f12) peptide is proline-rich. Both peptides (f8 and f12) showed antimicrobial activities against both Gram-positive and Gram-negative bacteria. Fraction 8 (f8) exhibits growth stimulating activity in 3T3 cell line and f12 shows higher free radical scavenging activity in comparison to other fractions. Finally, both peptides were in silico evaluated and some insights into their mechanism of action were provided. Thus, results indicate that these identified peptides have multiple biological activities which are valuable for the quick development of the neonate and may be considered as potential biotechnological products for nutraceutical industry. PMID:24703967

  10. A Multifunctional Coating for Autonomous Corrosion Control

    NASA Technical Reports Server (NTRS)

    Calle, Luz M.; Hintze, Paul E.; Li, Wenyan; Buhrow, Jerry W.; Jolley, Scott T.

    2010-01-01

    Corrosion is a destructive process that often causes failure in metallic components and structures. Protective coatings are the most commonly used method of corrosion control. However, progressively stricter environmental regulations have resulted in the ban of many commercially available corrosion protective coatings due to the harmful effects of their solvents or corrosion inhibitors. This work concerns the development of a multifunctional, smart coating for the autonomous control of corrosion. This coating is being developed to have the inherent ability to detect the chemical changes associated with the onset of corrosion and respond autonomously to control it. The multi-functionality of the coating is based on microencapsulation technology specifically designed for corrosion control applications. This design has, in addition to all the advantages of other existing microcapsules designs, the corrosion controlled release function that allows the delivery of corrosion indicators and inhibitors on demand only when and where they are needed. Corrosion indicators as well as corrosion inhibitors have been incorporated into the microcapsules, blended into several paint systems, and tested for corrosion detection and protection efficacy.

  11. Multifunctional matrices for oral peptide delivery.

    PubMed

    Bernkop-Schnürch, A; Walker, G

    2001-01-01

    The oral administration of peptide drugs represents one of the greatest challenges in pharmaceutical technology. To gain a sufficient bioavailability of these therapeutic agents, various barriers including the mucus-layer barrier, the enzymatic barrier, and the membrane barrier have to be overcome. A promising strategy for achieving this goal is the use of multifunctional matrices. These matrices are based on polymers that display mucoadhesive properties, a permeation-enhancing effect, enzyme-inhibiting properties, and/or a high buffer capacity. Moreover, a sustained or delayed drug release can be provided by delivery systems that contain such polymers. Among them, polyacrylates, cellulose derivatives, and chitosan are promising excipients that can also be customized by chemical modification to improve certain properties. For example, the covalent attachment of thiol moieties on these polymers leads to improved mucoadhesive and permeation-enhancing properties, and the conjugation of enzyme inhibitors enables the matrices to provide protection for peptide drugs against enzymatic degradation. The efficacy of multifunctional matrices in oral peptide delivery has been verified by various in vivo studies that could pave the way for the development of commercially viable formulations. PMID:11763498

  12. Multifunctional landscapes--perspectives for the future.

    PubMed

    Brandt, Jesper

    2003-03-01

    New methods in landscape ecology to study the link between landscape heterogeneity and landscape functionality are needed. Heterogeneity is a basic characteristic of landscape, and landscape function is the capacity to change the structural heterogeneity of a landscape system. In most developed countries the industrialisation of agriculture has in general resulted in a change of agricultural landscapes from a small-grained heterogeneous pattern towards more monotonous and monofunctional landscapes. During the 1990's this trends seem to have changed due to a diversification of rural land use, and new trends in ubanisation. Whether these phases of landscape development should be expected in developing countries is a totally open question. Dealing with the study of multifunctionality of landscapes it is proposed to distinguish between ecological functionality of landscape ecosystems, functionality pertaining to land use and social functionality. Further, the relation between function, space and scale is important by the determination of spatial and time segregation as well as spatial and time integration of multifunctionality in landscapes. PMID:12765260

  13. Multifunction Habitat Workstation/OLED Development

    NASA Technical Reports Server (NTRS)

    Schumacher, Shawn; Salazar, George; Schmidt, Oron

    2013-01-01

    This paper gives a general outline of both a multifunction habitat workstation and the research put into an Organic Light Emitting Diode (OLED) device. It first covers the tests that the OLED device will go through to become flight ready along with reasoning. Guidelines for building an apparatus to house the display and its components are given next, with the build of such following. The three tests the OLED goes through are presented (EMI, Thermal/Vac, Radiation) along with the data recovered. The second project of a multifunction workstation is then discussed in the same pattern. Reasoning for building such a workstation with telepresence in mind is offered. Build guidelines are presented first, with the build timeline following. Building the workstation will then be shown in great detail along with accompanying photos. Once the workstation has been discussed, the versatility of its functions are given. The paper concludes with future views and concepts that can added when the time or technology presents itself.

  14. Designing multifunctional landscapes for forest conservation

    NASA Astrophysics Data System (ADS)

    Santika, Truly; Meijaard, Erik; Wilson, Kerrie A.

    2015-11-01

    A multifunctional landscape approach to forest protection has been advocated for tropical countries. Designing such landscapes necessitates that the role of different land uses in protecting forest be evaluated, along with the spatial interactions between land uses. However, such evaluations have been hindered by a lack of suitable analysis methodologies and data with fine spatial resolution over long time periods. We demonstrate the utility of a matching method with multiple categories to evaluate the role of alternative land uses in protecting forest. We also assessed the impact of land use change trajectories on the rate of deforestation. We employed data from Kalimantan (Indonesian Borneo) at three different time periods during 2000-2012 to illustrate our approach. Four single land uses (protected areas (PA), natural forest logging concessions (LC), timber plantation concessions (TC) and oil-palm plantation concessions (OC)) and two mixed land uses (mixed concessions and the overlap between concessions and PA) were assessed. The rate of deforestation was found to be lowest for PA, followed by LC. Deforestation rates for all land uses tended to be highest for locations that share the characteristics of areas in which TC or OC are located (e.g. degraded areas), suggesting that these areas are inherently more susceptible to deforestation due to foregone opportunities. Our approach provides important insights into how multifunctional landscapes can be designed to enhance the protection of biodiversity.

  15. Advanced Multifunctional MMOD Shield: Radiation Shielding Assessment

    NASA Technical Reports Server (NTRS)

    Rojdev, Kristina; Christiansen, Eric

    2013-01-01

    As NASA is looking to explore further into deep space, multifunctional materials are a necessity for decreasing complexity and mass. One area where multifunctional materials could be extremely beneficial is in the micrometeoroid orbital debris (MMOD) shield. A typical MMOD shield on the International Space Station (ISS) is a stuffed whipple shield consisting of multiple layers. One of those layers is the thermal blanket, or multi-layer insulation (MLI). Increasing the MMOD effectiveness of MLI blankets, while still preserving their thermal capabilities, could allow for a less massive MMOD shield. Thus, a study was conducted to evaluate a concept MLI blanket for an MMOD shield. In conjunction, this MLI blanket and the subsequent MMOD shield was also evaluated for its radiation shielding effectiveness towards protecting crew. The overall MMOD shielding system using the concept MLI blanket proved to only have a marginal increase in the radiation mitigating properties. Therefore, subsequent analysis was performed on various conceptual MMOD shields to determine the combination of materials that may prove superior for radiation mitigating purposes. The following paper outlines the evaluations performed and discusses the results and conclusions of this evaluation for radiation shielding effectiveness.

  16. Multifunctional Microtubule-Associated Proteins in Plants

    PubMed Central

    Krtková, Jana; Benáková, Martina; Schwarzerová, Kateřina

    2016-01-01

    Microtubules (MTs) are involved in key processes in plant cells, including cell division, growth and development. MT-interacting proteins modulate MT dynamics and organization, mediating functional and structural interaction of MTs with other cell structures. In addition to conventional microtubule-associated proteins (MAPs) in plants, there are many other MT-binding proteins whose primary function is not related to the regulation of MTs. This review focuses on enzymes, chaperones, or proteins primarily involved in other processes that also bind to MTs. The MT-binding activity of these multifunctional MAPs is often performed only under specific environmental or physiological conditions, or they bind to MTs only as components of a larger MT-binding protein complex. The involvement of multifunctional MAPs in these interactions may underlie physiological and morphogenetic events, e.g., under specific environmental or developmental conditions. Uncovering MT-binding activity of these proteins, although challenging, may contribute to understanding of the novel functions of the MT cytoskeleton in plant biological processes. PMID:27148302

  17. Multifunctional porous silicon nanoparticles for cancer theranostics.

    PubMed

    Wang, Chang-Fang; Sarparanta, Mirkka P; Mäkilä, Ermei M; Hyvönen, Maija L K; Laakkonen, Pirjo M; Salonen, Jarno J; Hirvonen, Jouni T; Airaksinen, Anu J; Santos, Hélder A

    2015-04-01

    Nanomaterials provide a unique platform for the development of theranostic systems that combine diagnostic imaging modalities with a therapeutic payload in a single probe. In this work, dual-labeled iRGD-modified multifunctional porous silicon nanoparticles (PSi NPs) were prepared from dibenzocyclooctyl (DBCO) modified PSi NPs by strain-promoted azide-alkyne cycloaddition (SPAAC) click chemistry. Hydrophobic antiangiogenic drug, sorafenib, was loaded into the modified PSi NPs to enhance the drug dissolution rate and improve cancer therapy. Radiolabeling of the developed system with (111)In enabled the monitoring of the in vivo biodistribution of the nanocarrier by single photon emission computed tomography (SPECT) in an ectopic PC3-MM2 mouse xenograft model. Fluorescent labeling with Alexa Fluor 488 was used to determine the long-term biodistribution of the nanocarrier by immunofluorescence at the tissue level ex vivo. Modification of the PSi NPs with an iRGD peptide enhanced the tumor uptake of the NPs when administered intravenously. After intratumoral delivery the NPs were retained in the tumor, resulting in efficient tumor growth suppression with particle-loaded sorafenib compared to the free drug. The presented multifunctional PSi NPs highlight the utility of constructing a theranostic nanosystems for simultaneous investigations of the in vivo behavior of the nanocarriers and their drug delivery efficiency, facilitating the selection of the most promising materials for further NP development. PMID:25701036

  18. REACH. Residential Electrical Wiring Units.

    ERIC Educational Resources Information Center

    Ansley, Jimmy; Ennis, Mike

    As a part of the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this student manual contains individualized instructional units in the area of residential electrical wiring. The instructional units focus on grounded outlets, service entrance, and blueprint reading. Each unit follows a typical format…

  19. Residential School for the Gifted.

    ERIC Educational Resources Information Center

    Weatherly, Myra

    1981-01-01

    Briefly described is the program of the North Carolina School of Science and Mathematics, a residential program for gifted high school juniors and seniors which opened in 1980. Noted are the admission process, annual cost, course offerings, the work program, and attitudes of faculty and students. (DB)

  20. Functional Assessment in Residential Treatment

    ERIC Educational Resources Information Center

    Tidwell, W. Guy

    2006-01-01

    This paper covers the application of functional behavioral assessment (FBA) to treatment of problem behavior in residential facilities. Basic behavioral concepts are covered with emphasis on antecedent events and their importance in assessment and treatment. The paper focuses on two types of assessment, the behavioral interview and A-B-C narrative…

  1. Residential Mobility and Adolescent Violence

    ERIC Educational Resources Information Center

    Haynie, Dana L.; South, Scott J.

    2005-01-01

    Using two waves of data from the National Longitudinal Study of Adolescent Health, this study examines the impact of recent residential mobility on adolescent violence. A unique focus of our analysis is an examination of the ability of various mechanisms, including parent-child relationships, psychological distress, experiences of victimization,…

  2. Biotic homogenization can decrease landscape-scale forest multifunctionality.

    PubMed

    van der Plas, Fons; Manning, Pete; Soliveres, Santiago; Allan, Eric; Scherer-Lorenzen, Michael; Verheyen, Kris; Wirth, Christian; Zavala, Miguel A; Ampoorter, Evy; Baeten, Lander; Barbaro, Luc; Bauhus, Jürgen; Benavides, Raquel; Benneter, Adam; Bonal, Damien; Bouriaud, Olivier; Bruelheide, Helge; Bussotti, Filippo; Carnol, Monique; Castagneyrol, Bastien; Charbonnier, Yohan; Coomes, David Anthony; Coppi, Andrea; Bastias, Cristina C; Dawud, Seid Muhie; De Wandeler, Hans; Domisch, Timo; Finér, Leena; Gessler, Arthur; Granier, André; Grossiord, Charlotte; Guyot, Virginie; Hättenschwiler, Stephan; Jactel, Hervé; Jaroszewicz, Bogdan; Joly, François-Xavier; Jucker, Tommaso; Koricheva, Julia; Milligan, Harriet; Mueller, Sandra; Muys, Bart; Nguyen, Diem; Pollastrini, Martina; Ratcliffe, Sophia; Raulund-Rasmussen, Karsten; Selvi, Federico; Stenlid, Jan; Valladares, Fernando; Vesterdal, Lars; Zielínski, Dawid; Fischer, Markus

    2016-03-29

    Many experiments have shown that local biodiversity loss impairs the ability of ecosystems to maintain multiple ecosystem functions at high levels (multifunctionality). In contrast, the role of biodiversity in driving ecosystem multifunctionality at landscape scales remains unresolved. We used a comprehensive pan-European dataset, including 16 ecosystem functions measured in 209 forest plots across six European countries, and performed simulations to investigate how local plot-scale richness of tree species (α-diversity) and their turnover between plots (β-diversity) are related to landscape-scale multifunctionality. After accounting for variation in environmental conditions, we found that relationships between α-diversity and landscape-scale multifunctionality varied from positive to negative depending on the multifunctionality metric used. In contrast, when significant, relationships between β-diversity and landscape-scale multifunctionality were always positive, because a high spatial turnover in species composition was closely related to a high spatial turnover in functions that were supported at high levels. Our findings have major implications for forest management and indicate that biotic homogenization can have previously unrecognized and negative consequences for large-scale ecosystem multifunctionality. PMID:26979952

  3. Next-Generation Multifunctional Electrochromic Devices.

    PubMed

    Cai, Guofa; Wang, Jiangxin; Lee, Pooi See

    2016-08-16

    The rational design and exploration of electrochromic devices will find a wide range of applications in smart windows for energy-efficient buildings, low-power displays, self-dimming rear mirrors for automobiles, electrochromic e-skins, and so on. Electrochromic devices generally consist of multilayer structures with transparent conductors, electrochromic films, ion conductors, and ion storage films. Synthetic strategies and new materials for electrochromic films and transparent conductors, comprehensive electrochemical kinetic analysis, and novel device design are areas of active study worldwide. These are believed to be the key factors that will help to significantly improve the electrochromic performance and extend their application areas. In this Account, we present our strategies to design and fabricate electrochromic devices with high performance and multifunctionality. We first describe the synthetic strategies, in which a porous tungsten oxide (WO3) film with nearly ideal optical modulation and fast switching was prepared by a pulsed electrochemical deposition method. Multiple strategies, such as sol-gel/inkjet printing methods, hydrothermal/inkjet printing methods, and a novel hybrid transparent conductor/electrochromic layer have been developed to prepare high-performance electrochromic films. We then summarize the recent advances in transparent conductors and ion conductor layers, which play critial roles in electrochromic devices. Benefiting from the developments of soft transparent conductive substrates, highly deformable electrochromic devices that are flexible, foldable, stretchable, and wearable have been achieved. These emerging devices have great potential in applications such as soft displays, electrochromic e-skins, deformable electrochromic films, and so on. We finally present a concept of multifunctional smart glass, which can change its color to dynamically adjust the daylight and solar heat input of the building or protect the users' privacy

  4. Multifunctional nanoparticles as coupled contrast agents

    PubMed Central

    Jin, Yongdong; Jia, Congxian; Huang, Sheng-Wen; O’Donnell, Matthew; Gao, Xiaohu

    2011-01-01

    Engineering compact imaging probes with highly integrated modalities is a key focus in bionanotechnology and will have profound impact on molecular diagnostics, imaging, and therapeutics. However, combining multiple components on a nanometer scale to create new imaging modalities unavailable from individual components has proven challenging. Here, we demonstrate iron oxide and gold coupled core-shell nanoparticles with well defined structural characteristics (e.g., size, shell thickness, and core-shell separation) and physical properties (e.g., electronic, magnetic, optical, thermal, and acoustic). The resulting multifunctional nanoprobes not only offer contrast for electron microscopy, magnetic resonance imaging, and scattering-based imaging, but more importantly, enable a new imaging mode, magnetomotive photoacoustic (mmPA) imaging, with remarkable contrast enhancement compared to PA images using conventional nanoparticle contrast agents. PMID:20975706

  5. Multifunctional iron oxide nanoparticles for biomedical applications

    NASA Astrophysics Data System (ADS)

    Bloemen, M.; Denis, C.; Van Stappen, T.; De Meester, L.; Geukens, N.; Gils, A.; Verbiest, T.

    2015-03-01

    Multifunctional nanoparticles have attracted a lot of attention since they can combine interesting properties like magnetism, fluorescence or plasmonic effects. As a core material, iron oxide nanoparticles have been the subject of intensive research. These cost-effective and non-toxic particles are used nowadays in many applications. We developed a heterobifunctional PEG ligand that can be used to introduce functional groups (carboxylic acids) onto the surface of the NP. Via click chemistry, a siloxane functionality was added to this ligand, for a subsequent covalent ligand exchange reaction. The functionalized nanoparticles have an excellent colloidal stability in complex environments like buffers and serum or plasma. Antibodies were coupled to the introduced carboxylic acids and these NP-antibody bioconjugates were brought into contact with Legionella bacteria for magnetic separation experiments.

  6. Multiscale Multifunctional Progressive Fracture of Composite Structures

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.; Minnetyan, L.

    2012-01-01

    A new approach is described for evaluating fracture in composite structures. This approach is independent of classical fracture mechanics parameters like fracture toughness. It relies on computational simulation and is programmed in a stand-alone integrated computer code. It is multiscale, multifunctional because it includes composite mechanics for the composite behavior and finite element analysis for predicting the structural response. It contains seven modules; layered composite mechanics (micro, macro, laminate), finite element, updating scheme, local fracture, global fracture, stress based failure modes, and fracture progression. The computer code is called CODSTRAN (Composite Durability Structural ANalysis). It is used in the present paper to evaluate the global fracture of four composite shell problems and one composite built-up structure. Results show that the composite shells. Global fracture is enhanced when internal pressure is combined with shear loads. The old reference denotes that nothing has been added to this comprehensive report since then.

  7. AEGIS - Advanced Multi-Function Array Radar

    NASA Astrophysics Data System (ADS)

    Phillips, C. C.

    1981-12-01

    The AMFAR (Advanced Multi-Function Array Radar), a radar system technology developed in the late 1960s, has demonstrated automatic detection and tracking of all air targets plus inherent resistance to natural and man-made clutter with computer control of the radar. The major elements of the AMFAR - a high-power radar frequency transmitter, a phased-array antenna, a signal processor system, a computer control system, and an automated test system - are described in detail. The capabilities of the radar are demonstrated in a series of pictures showing processing steps to provide automatic target detection and track in both ground clutter zones and rain clutter. The success of AMFAR laid the foundation of Radar System AN/SPY-1A, the Weapon Control Radar System now being produced as a major element of the AEGIS Weapon System for the U.S. Navy guided missile cruiser Ticonderoga.

  8. Overview of GSE as a multifunctional GUI

    NASA Astrophysics Data System (ADS)

    Kurtovich, Boyan; Malangone, Fabio; Voss, David L.; Carssow, Douglas B.; Fritz, Theodore A.; Mavretic, Anton

    2009-08-01

    Ground Support Equipment (GSE) [1] is a versatile and multifunctional graphical user interface (GUI) and a software/hardware platform. It is a custom-designed system executed in the LabVIEW programming language to serve as an instrument health monitor for the Loss Cone Imager (LCI) satellite project. GSE mimics the behavior of the onboard Experiment Computer System (ECS). Its functions comprise the measurement of voltage, current, and power, as well as acting as a safety mechanism in case of any anomalous condition (e.g., over-current and/or over-voltage situation). Individual log files record the sessions during which data is gathered and analyzed. Safety/warning alarm flags shall be 'visible' from any individual window/tab. Analog-to-Digital Conversion (ADC) particle group measurements will be displayed on six individual panels. GSE will be supplemented with a comprehensive user's manual for added clarity.

  9. Photopolymeric multifunctional dendrimer toward holographic applications.

    PubMed

    Jeong, Yong-Cheol; Jung, Bokyung; Park, Jung-Ki

    2012-09-26

    We present a photopolymeric multifunctional dendrimer for holographic applications. In this study, we described a synthesis of multiphotoreactive dendrimer and phase compatible polymer matrix as well as a numerical simulation of the dendrimer. This holographic photopolymer containing a nanosized photoreactive organic dendrimer could address the aggregation issue of conventional inorganic nanoparticle additives and allowed writing-induced shrinkage to be successfully reduced to the extent of acceptable values for 130 μm thick film. In this report, holographic performance including diffraction efficiency (DE), transmission, photosensitivity, modulation of refractive index, polarization sensitivity, and volume shrinkage has been discussed. The page-wise recording by using an amplitude spatial light modulator (SLM) was also demonstrated. PMID:22950741

  10. Multifunctional pulse sequence generator for pulse NMR

    NASA Astrophysics Data System (ADS)

    Wang, Dongsheng

    1988-06-01

    A new multifunctional pulse sequence generator has been designed and constructed. It can conveniently generate various pulse sequences used in nuclear-magnetic resonance (NMR) to measure the spin-lattice relaxation time T1, the spin-spin relaxation time T2, and the spin-locking relaxation time T1 ρ. It can also be used in pulse Fourier transform NMR and double resonance. The intervals of pulses can increase automatically with sequence repetitions and the generator can be used in two-dimensional spectrum measurement and spin-density imaging research. The sequences can be generated through four different triggering methods and there are two synchronous pulse outputs and fifteen auxiliary pulse outputs, so the generator can be conveniently interfaced with a computer or other instruments. The circuitry, functions, and features of the generator are described in this article.

  11. Artificial neural network for multifunctional areas.

    PubMed

    Riccioli, Francesco; El Asmar, Toufic; El Asmar, Jean-Pierre; Fagarazzi, Claudio; Casini, Leonardo

    2016-01-01

    The issues related to the appropriate planning of the territory are particularly pronounced in highly inhabited areas (urban areas), where in addition to protecting the environment, it is important to consider an anthropogenic (urban) development placed in the context of sustainable growth. This work aims at mathematically simulating the changes in the land use, by implementing an artificial neural network (ANN) model. More specifically, it will analyze how the increase of urban areas will develop and whether this development would impact on areas with particular socioeconomic and environmental value, defined as multifunctional areas. The simulation is applied to the Chianti Area, located in the province of Florence, in Italy. Chianti is an area with a unique landscape, and its territorial planning requires a careful examination of the territory in which it is inserted. PMID:26718948

  12. Multifunctional composite core-shell nanoparticles

    NASA Astrophysics Data System (ADS)

    Wei, Suying; Wang, Qiang; Zhu, Jiahua; Sun, Luyi; Lin, Hongfei; Guo, Zhanhu

    2011-11-01

    In this review paper, the state-of-the-art knowledge of the core-shell multifunctional nanoparticles (MNPs), especially with unique physiochemical properties, is presented. The synthesis methods were summarized from the aspects of both the advantages and the demerits. The core includes the inexpensive and easily oxidized metals and the noble shells include the relatively noble metals, carbon, silica, other oxides, and polymers. The properties including magnetic, optical, anti-corrosion and the surface chemistry of the NPs are thoroughly reviewed. The current status of the applications is reviewed with the detailed examples including the catalysis, giant magnetoresistance (GMR) sensing, electromagnetic interface shielding or microwave absorption, biomedical drug delivery, and the environmental remediation.

  13. Multifunctional Micellar Nanomedicine for Cancer Therapy

    PubMed Central

    Blanco, Elvin; Kessinger, Chase W.; Sumer, Baran D.; Gao, Jinming

    2010-01-01

    Polymeric micelles are supramolecular, core-shell nanoparticles that offer considerable advantages for cancer diagnosis and therapy. Their relatively small size (10-100 nm), ability to solubilize hydrophobic drugs as well as imaging agents, and improved pharmacokinetics provide a useful bioengineering platform for cancer applications. Several polymeric micelle formulations are currently undergoing phase I/II clinical trials, which have shown improved antitumor efficacy and reduced systemic toxicity. This minireview will focus on recent advancements in the multifunctional design of micellar nanomedicine with tumor targeting, stimulated drug release, and cancer imaging capabilities. Such functionalization strategies result in enhanced micellar accumulation at tumor sites, higher drug bioavailability, as well as improved tumor diagnosis and visualization of therapy. Ultimately, integrated nanotherapeutic systems (e.g., theranostic nanomedicine) may prove essential to address the challenges of tumor heterogeneity and adaptive resistance to achieve efficacious treatment of cancer. PMID:19064945

  14. On Multifunctional Collaborative Methods in Engineering Science

    NASA Technical Reports Server (NTRS)

    Ransom, Jonathan B.

    2001-01-01

    Multifunctional methodologies and analysis procedures are formulated for interfacing diverse subdomain idealizations including multi-fidelity modeling methods and multi-discipline analysis methods. These methods, based on the method of weighted residuals, ensure accurate compatibility of primary and secondary variables across the subdomain interfaces. Methods are developed using diverse mathematical modeling (i.e., finite difference and finite element methods) and multi-fidelity modeling among the subdomains. Several benchmark scalar-field and vector-field problems in engineering science are presented with extensions to multidisciplinary problems. Results for all problems presented are in overall good agreement with the exact analytical solution or the reference numerical solution. Based on the results, the integrated modeling approach using the finite element method for multi-fidelity discretization among the subdomains is identified as most robust. The multiple method approach is advantageous when interfacing diverse disciplines in which each of the method's strengths are utilized.

  15. 3D Multifunctional Ablative Thermal Protection System

    NASA Technical Reports Server (NTRS)

    Feldman, Jay; Venkatapathy, Ethiraj; Wilkinson, Curt; Mercer, Ken

    2015-01-01

    NASA is developing the Orion spacecraft to carry astronauts farther into the solar system than ever before, with human exploration of Mars as its ultimate goal. One of the technologies required to enable this advanced, Apollo-shaped capsule is a 3-dimensional quartz fiber composite for the vehicle's compression pad. During its mission, the compression pad serves first as a structural component and later as an ablative heat shield, partially consumed on Earth re-entry. This presentation will summarize the development of a new 3D quartz cyanate ester composite material, 3-Dimensional Multifunctional Ablative Thermal Protection System (3D-MAT), designed to meet the mission requirements for the Orion compression pad. Manufacturing development, aerothermal (arc-jet) testing, structural performance, and the overall status of material development for the 2018 EM-1 flight test will be discussed.

  16. Multifunctional carbon nanohorn complexes for cancer treatment.

    PubMed

    Chechetka, Svetlana A; Pichon, Benoit; Zhang, Minfang; Yudasaka, Masako; Bégin-Colin, Sylvie; Bianco, Alberto; Miyako, Eijiro

    2015-01-01

    Multifunctional carbon nanohorn (CNH) complexes were synthesized using oxidized CNH, magnetite (MAG) nanoparticles, and polyethyleneimine (PEI). The ferromagnetic MAG nanoparticles were loaded onto CNH (MAG-CNH) using iron(II) acetate and subsequent heat treatment. Chemical functionalization of the MAG-CNH complexes with PEI improved their water-dispersibility and allowed further conjugation with a fluorophore. The application of an external magnetic field significantly intensified the targeted vectorization of CNH complexes into human cervical cancer (HeLa) cells. Following cell uptake, laser irradiation of the cells showed a significant enhancement in the photothermal effects of CNHs leading to cell death. We have confirmed that the photothermal properties and ferromagnetic characteristics of CNH complexes show efficient cell elimination. The present study is an essential step toward the development of an innovative cancer therapy and a highly sensitive detection of cancer cells at the single-cell level. PMID:25319234

  17. MULTIFUNCTIONAL SOLAR ENERGY SYSTEMS RESEARCH PROJECT

    SciTech Connect

    Byard Wood, Lance Seefeldt, Ronald Sims, Bradley Wahlen, and Dan Dye

    2012-06-29

    The solar energy available within the visible portion of the solar spectrum is about 300 W/m2 (43%) and that available in the UV and IR portion is about 400 W/m2 (57%). This provides opportunities for developing integrated energy systems that capture and use specific wavelengths of the solar spectrum for different purposes. For example: biofuels from photosynthetic microbes use only the visible light; solar cells use a narrow band of the solar spectrum that could be either mostly in the visible or in the IR regions of the solar spectrum, depending on the photovoltaic materials, e.g., gallium antimonide (GaSb) cells utilize predominately IR radiation; and finally, solar panels that heat water utilize a broad range of wavelengths (visible plus IR). The basic idea of this research is that sunlight has many possible end-use applications including both direct use and energy conversion schemes; it is technically feasible to develop multifunctional solar energy systems capable of addressing several end-use needs while increasing the overall solar energy utilization efficiency when compared to single-purpose solar technologies. Such a combination of technologies could lead to more cost-competitive ?multifunctional? systems that add value and broaden opportunities for integrated energy systems. The goal of this research is to increase the overall energy efficacy and cost competitiveness of solar systems. The specific objectives of this research were: 1) Evaluate the efficacy of a combined photobioreactor and electric power system; 2) Improve the reliability and cost effectiveness of hybrid solar lighting systems ? a technology in which sunlight is collected and distributed via optical fibers into the interior of a building; 3) Evaluate the efficacy of using filtered light to increase the production of biomass in photobioreactors and provide more solar energy for other uses; 4) Evaluates several concepts for wavelength shifting such that a greater percentage of the solar

  18. Advanced Multifunctional MMOD Shield: Radiation Shielding Assessment

    NASA Technical Reports Server (NTRS)

    Rojdev, Kristina; Christiansen, Eric

    2011-01-01

    As NASA is looking to explore further into deep space, multifunctional materials are a necessity for decreasing complexity and mass. One area where multifunctional materials could be extremely beneficial is in the micrometeoroid orbital debris (MMOD) shield. A typical MMOD shield on the International Space Station (ISS) is a stuffed whipple shield consisting of multiple layers. One of those layers is the thermal blanket, or multi-layer insulation (MLI). By increasing the MMOD effectiveness of MLI blankets, while still preserving their thermal capabilities, could allow for a less massive MMOD shield. Thus, a study was conducted to evaluate concept MLI blankets for MMOD shields. In conjunction, these MLI blankets and the subsequent MMOD shields were also evaluated for their radiation shielding effectiveness towards protecting crew. These concepts were evaluated against the ISS MLI blankets and the ISS MMOD shield, which acted as the baseline. These radiation shielding assessments were performed using the high charge and energy transport software (HZETRN). This software is based on a one-dimensional formula of the Boltzmann transport equation with a straight-ahead approximation. Each configuration was evaluated against the following environments to provide a diverse view of radiation shielding effectiveness in most space environments within the heliosphere: August 1972 solar particle event, October 1989 solar particle event, 1982 galactic cosmic ray environment (during solar maximum), 1987 galactic cosmic ray environment (during solar minimum), and a low earth orbit environment in 1970 that corresponded to an altitude of 400 km and inclination of 51.6 . Both the absorbed dose and the dose equivalent were analyzed, but the focus of the discussion was on the dose equivalent since the data is most concerned with radiation shielding of the crew. The following paper outlines the evaluations performed and discusses the results and conclusions of this evaluation for

  19. Evaluation of recent residential inverters

    SciTech Connect

    Nichols, B.E.

    1982-06-01

    Seven residential utility-interactive inverters for photovoltaic power systems have been evaluated at MIT Laboratory and at the Northeast Residential Experiment Station (NE RES). Two, a Windworks Gemini and an Abacus Sunverter, have been reported on previously. Reviewed here are five other inverters: Windworks Gemini 8-kW (dc) model with an ac filter to improve the output current waveform and power factor; Acheval Wind Electronics 10-kW (ac) model, Helionetics 6-kW (dc) model; and American Power Conversion 2-kW and 4-kW (ac) models. Input and output power, power factor, current waveform distortion, audio noise and radio frequency interference measurements were made at the NE RES and the results are presented.

  20. Integrated residential photovoltaic array development

    NASA Astrophysics Data System (ADS)

    Shepard, N. F., Jr.

    1981-02-01

    An optimum integrated residential photovoltaic array/module is addressed. Nineteen existing or proposed systems intended for residential applications are described. Each of these systems is rated against a comprehensive set of evaluation criteria in an effort to formulate three module design concepts for further study and analysis. This evaluation led to a number of observations which are enumerated and should be considered in future module and array designs. Three module concepts are presented as baseline design approaches to be further analyzed and optimized. These options include: (1) a rectangular, direct mounted, shingle type module; (2) an integrally mounted module with nonconductive exposed elements; and (3) an aluminum framed, stand off module. Preliminary design drawings are presented for each of these module configurations.

  1. Integrated residential photovoltaic array development

    NASA Technical Reports Server (NTRS)

    Shepard, N. F., Jr.

    1981-01-01

    An optimum integrated residential photovoltaic array/module is addressed. Nineteen existing or proposed systems intended for residential applications are described. Each of these systems is rated against a comprehensive set of evaluation criteria in an effort to formulate three module design concepts for further study and analysis. This evaluation led to a number of observations which are enumerated and should be considered in future module and array designs. Three module concepts are presented as baseline design approaches to be further analyzed and optimized. These options include: (1) a rectangular, direct mounted, shingle type module; (2) an integrally mounted module with nonconductive exposed elements; and (3) an aluminum framed, stand off module. Preliminary design drawings are presented for each of these module configurations.

  2. PERMEATION OF MULTIFUNCTIONAL ACRYLATES THROUGH THREE PROTECTIVE CLOTHING MATERIALS

    EPA Science Inventory

    Permeation tests were conducted with trimethylolpropane triacrylate TMPTA), 1,6-hexanediol diacrylate (HDDA), and two mixtures of 1,6-hexanediol diacrylate with 2-ethylhexyl acrylate (EHA) to better understand the permeation behavior of multifunctional acrylate compounds. he test...

  3. PERMEATION OF MULTIFUNCTIONAL ACRYLATES THROUGH SELECTED PROTECTIVE GLOVE MATERIALS

    EPA Science Inventory

    In support of the Premanufacture Notification (PMN) program of the Environmental Protection Agency's Office of Toxic Substances, the resistance of three glove materials to permeation by multifunctional acrylate compounds was evaluated through a program for the Office of Research ...

  4. Staff supervision in residential care.

    PubMed

    Myers, Peter G; Bibbs, Tonya; Orozco, Candy

    2004-04-01

    Residential care workers must be offered opportunities for formalized and systematic supervision in individual and group formats to provide the highest possible level of care to children and adolescents whom they serve. Effective supervision with residential care staff should be open to exploring issues at all levels of their experience and in relation to each component of the broader organizational structure within which they work. Systems theory offers a useful lens through which to view supervising staff in residential treatment. Systems theory proposes that human behavior is shaped by interactional processes and internal factors. Although the development of the individual occurs within intrinsic cognitive and emotional spheres, it also is believed to be related to several other elements. These additional variables include the point at which the family and system function in their own life cycle, the historical and current emotional context, the current and changing structure of the system, narratives, and the cultural context. This article discussed how methods of training and supervision would be most effective if they were designed specifically for the developmental level of the participants. Some literature reviews have concluded that youth care workers, like all professionals, pass through developmental stages and progress through them in their work. To assist youth care workers in their jobs, supervisors must understand these stages and the ways in which they may be enacted in the workplace. PMID:15062348

  5. A review of multifunctional structure technology for aerospace applications

    NASA Astrophysics Data System (ADS)

    Sairajan, K. K.; Aglietti, G. S.; Mani, K. M.

    2016-03-01

    The emerging field of multifunctional structure (MFS) technologies enables the design of systems with reduced mass and volume, thereby improving their overall efficiency. It requires developments in different engineering disciplines and their integration into a single system without degrading their individual performances. MFS is particularly suitable for aerospace applications where mass and volume are critical to the cost of the mission. This article reviews the current state of the art of multifunctional structure technologies relevant to aerospace applications.

  6. Comparative review of multifunctionality and ecosystem services in sustainable agriculture.

    PubMed

    Huang, Jiao; Tichit, Muriel; Poulot, Monique; Darly, Ségolène; Li, Shuangcheng; Petit, Caroline; Aubry, Christine

    2015-02-01

    Two scientific communities with broad interest in sustainable agriculture independently focus on multifunctional agriculture or ecosystem services. These communities have limited interaction and exchange, and each group faces research challenges according to independently operating paradigms. This paper presents a comparative review of published research in multifunctional agriculture and ecosystem services. The motivation for this work is to improve communication, integrate experimental approaches, and propose areas of consensus and dialog for the two communities. This extensive analysis of publication trends, ideologies, and approaches enables formulation of four main conclusions. First, the two communities are closely related through their use of the term "function." However, multifunctional agriculture considers functions as agricultural activity outputs and prefers farm-centred approaches, whereas ecosystem services considers ecosystem functions in the provision of services and prefers service-centred approaches. Second, research approaches to common questions in these two communities share some similarities, and there would be great value in integrating these approaches. Third, the two communities have potential for dialog regarding the bundle of ecosystem services and the spectrum of multifunctional agriculture, or regarding land sharing and land sparing. Fourth, we propose an integrated conceptual framework that distinguishes six groups of ecosystem services and disservices in the agricultural landscape, and combines the concepts of multifunctional agriculture and ecosystem services. This integrated framework improves applications of multifunctional agriculture and ecosystem services for operational use. Future research should examine if the framework can be readily adapted for modelling specific problems in agricultural management. PMID:25463579

  7. Low multifunctional redundancy of soil fungal diversity at multiple scales.

    PubMed

    Mori, Akira S; Isbell, Forest; Fujii, Saori; Makoto, Kobayashi; Matsuoka, Shunsuke; Osono, Takashi

    2016-03-01

    Theory suggests that biodiversity might help sustain multiple ecosystem functions. To evaluate possible biodiversity-multifunctionality relationships in a natural setting, we considered different spatial scales of diversity metrics for soil fungi in the northern forests of Japan. We found that multifunctionality increased with increasing local species richness, suggesting a limited degree of multifunctional redundancy. This diversity-multifunctionality relationship was independent of the compositional uniqueness of each community. However, we still found the importance of community composition, because there was a positive correlation between community dissimilarity and multifunctional dissimilarity across the landscape. This result suggests that functional redundancy can further decrease when spatial variations in identities of both species and functions are simultaneously considered at larger spatial scales. We speculate that different scales of diversity could provide multiple levels of insurance against the loss of functioning if high-levels of local species diversity and compositional variation across locations are both maintained. Alternatively, making species assemblages depauperate may result in the loss of multifunctionality. PMID:26689733

  8. Genome-Wide Detection and Analysis of Multifunctional Genes

    PubMed Central

    Pritykin, Yuri; Ghersi, Dario; Singh, Mona

    2015-01-01

    Many genes can play a role in multiple biological processes or molecular functions. Identifying multifunctional genes at the genome-wide level and studying their properties can shed light upon the complexity of molecular events that underpin cellular functioning, thereby leading to a better understanding of the functional landscape of the cell. However, to date, genome-wide analysis of multifunctional genes (and the proteins they encode) has been limited. Here we introduce a computational approach that uses known functional annotations to extract genes playing a role in at least two distinct biological processes. We leverage functional genomics data sets for three organisms—H. sapiens, D. melanogaster, and S. cerevisiae—and show that, as compared to other annotated genes, genes involved in multiple biological processes possess distinct physicochemical properties, are more broadly expressed, tend to be more central in protein interaction networks, tend to be more evolutionarily conserved, and are more likely to be essential. We also find that multifunctional genes are significantly more likely to be involved in human disorders. These same features also hold when multifunctionality is defined with respect to molecular functions instead of biological processes. Our analysis uncovers key features about multifunctional genes, and is a step towards a better genome-wide understanding of gene multifunctionality. PMID:26436655

  9. Genome-Wide Detection and Analysis of Multifunctional Genes.

    PubMed

    Pritykin, Yuri; Ghersi, Dario; Singh, Mona

    2015-10-01

    Many genes can play a role in multiple biological processes or molecular functions. Identifying multifunctional genes at the genome-wide level and studying their properties can shed light upon the complexity of molecular events that underpin cellular functioning, thereby leading to a better understanding of the functional landscape of the cell. However, to date, genome-wide analysis of multifunctional genes (and the proteins they encode) has been limited. Here we introduce a computational approach that uses known functional annotations to extract genes playing a role in at least two distinct biological processes. We leverage functional genomics data sets for three organisms--H. sapiens, D. melanogaster, and S. cerevisiae--and show that, as compared to other annotated genes, genes involved in multiple biological processes possess distinct physicochemical properties, are more broadly expressed, tend to be more central in protein interaction networks, tend to be more evolutionarily conserved, and are more likely to be essential. We also find that multifunctional genes are significantly more likely to be involved in human disorders. These same features also hold when multifunctionality is defined with respect to molecular functions instead of biological processes. Our analysis uncovers key features about multifunctional genes, and is a step towards a better genome-wide understanding of gene multifunctionality. PMID:26436655

  10. Evaluation of evolving residential electricity tariffs

    SciTech Connect

    Lai, Judy; DeForest, Nicholas; Kiliccote, Sila; Stadler, Michael; Marnay, Chris; Donadee, Jon

    2011-05-15

    Residential customers in California's Pacific Gas and Electric (PG&E) territory have seen several electricity rate structure changes in the past decade. This poster: examines the history of the residential pricing structure and key milestones; summarizes and analyzes the usage between 2006 and 2009 for different baseline/climate areas; discusses the residential electricity Smart Meter roll out; and compares sample bills for customers in two climates under the current pricing structure and also the future time of use (TOU) structure.

  11. Impacts of changing residential oil burner technology

    SciTech Connect

    Butcher, T.; McDonald, R.; Krajewski, R.; Celebi, Y.; Andrews, J.

    1992-05-01

    This paper presents trends in oil-fired residential heating appliance design that take advantage of recent research which promises significantly lower pollutant emissions, improved performance, and efficiency.

  12. Surface-modified multifunctional MIP nanoparticles

    NASA Astrophysics Data System (ADS)

    Moczko, Ewa; Poma, Alessandro; Guerreiro, Antonio; Perez de Vargas Sansalvador, Isabel; Caygill, Sarah; Canfarotta, Francesco; Whitcombe, Michael J.; Piletsky, Sergey

    2013-04-01

    The synthesis of core-shell molecularly imprinted polymer nanoparticles (MIP NPs) has been performed using a novel solid-phase approach on immobilised templates. The same solid phase also acts as a protective functionality for high affinity binding sites during subsequent derivatisation/shell formation. This procedure allows for the rapid synthesis, controlled separation and purification of high-affinity materials, with each production cycle taking just 2 hours. The aim of this approach is to synthesise uniformly sized imprinted materials at the nanoscale which can be readily grafted with various polymers without affecting their affinity and specificity. For demonstration purposes we grafted anti-melamine MIP NPs with coatings which introduce the following surface characteristics: high polarity (PEG methacrylate); electro-activity (vinylferrocene); fluorescence (eosin acrylate); thiol groups (pentaerythritol tetrakis(3-mercaptopropionate)). The method has broad applicability and can be used to produce multifunctional imprinted nanoparticles with potential for further application in the biosensors, diagnostics and biomedical fields and as an alternative to natural receptors.The synthesis of core-shell molecularly imprinted polymer nanoparticles (MIP NPs) has been performed using a novel solid-phase approach on immobilised templates. The same solid phase also acts as a protective functionality for high affinity binding sites during subsequent derivatisation/shell formation. This procedure allows for the rapid synthesis, controlled separation and purification of high-affinity materials, with each production cycle taking just 2 hours. The aim of this approach is to synthesise uniformly sized imprinted materials at the nanoscale which can be readily grafted with various polymers without affecting their affinity and specificity. For demonstration purposes we grafted anti-melamine MIP NPs with coatings which introduce the following surface characteristics: high polarity

  13. Multifunctional hybrid optical/digital neural net

    NASA Astrophysics Data System (ADS)

    Casasent, David P.

    1990-08-01

    A multi-functional hybrid neural net is described. It is hybrid since it uses a digital hardware Hecht-Nielsen Corporation (HNC) neural net for adaptive learning and an optical neural net for on-line processing/classification. It is also hybrid in its combination of pattern recognition and neural net techniques. The system is multi-functional. It can function as an optimization and adaptive pattern recognition neural net as well as an auto and heteroassociative processor. I . W. JTRODUCTION Neural nets (NNs) have recently received enormous attention [1 -2] with increasing attention to the use of optical processors and a variety of new learning algorithms. Section 2 describes our hybrid NN with attention to Its fabrication and the role for optical and digital processors. Section 3 details Its use as an associative processor. Section 4 highlights is use in 3 optimization NN problems (a mixture NN a multitarget tracker (MTT) NN and a matrix inversion NN). Section 5 briefly notes it use as a production NN system and symbolic NN. Section 6 describes its use as an adaptive pattern recognition (PR) NN (that marries PR and NN techniques). 2. HYBRID ARCHITECTURE Figure 1 shows our basic hybrid NN [3]. The optical portion of the system is a matrix-vector (M-V) processor whose vector output P3 is the product of the vector at P1 and the matrix at P2. An HNC digital hardware NN is used during learning determine the interconnection weights forP2. If P2 is a spatial light modulator (SLM) its contents can be updated (using gated learning) from thedigital NN. The operations in most adaptive PR NN learning algorithms are sufficiently complex thatthey are best implemented digitally. In addition the learning operations required are often not well suited for optical realization for optimization NNs the weights are fixed and in adaptive learning learning is off-line and once completed the weights can often be fixed. Four gates are shown that determine the final output or the new P1

  14. Multifunctional composites: Healing, heating and electromagnetic integration

    NASA Astrophysics Data System (ADS)

    Plaisted, Thomas Anthony John

    2007-12-01

    Multifunctional materials, in the context of this research, integrate other functions into materials that foremost have outstanding structural integrity. Details of the integration of electromagnetic, heating, and healing functionalities into fiber-reinforced polymer composites are presented. As a result of fiber/wire integration through textile braiding and weaving, the dielectric constant of a composite may be tuned from negative to positive values. These wires are further leveraged to uniformly heat the composite through resistive heating. A healing functionality is introduced by utilizing a polymer matrix with the ability to heal internal cracking through thermally-reversible covalent bonds based on Diels-Alder cycloaddition. The Double Cleavage Drilled Compression (DCDC) specimen is applied to study the fracture and healing characteristics of the neat polymer. This method allows for quantitative evaluation of incremental crack growth, and ensures that the cracked sample remains in one piece after the test, improving the ability to re-align the fracture surfaces prior to healing. Initially, the fracture strength of PMMA is studied with various DCDC geometries to develop a model of the propagation of a crack within this type of specimen. Applied to the healable polymer (2MEP4F), repeated fracture-healing cycles demonstrate that treatment at temperatures between 85 to 95°C results in full fracture toughness recovery and no dimensional changes due to creep. The fracture toughness after each fracturing and healing cycle has been calculated, using the model, to yield a fracture toughness of about 0.71 MPa·m1/2 for this material at room temperature. Glass and carbon fiber-reinforced composites have been fabricated with the 2MEP4F polymer, and the ability of this polymer to heal microcracks in fiber-reinforced composites is demonstrated. Microcracks have been introduced into the composites by cryogenic cycling in liquid nitrogen, causing a reduction in the storage

  15. Measuring Homelessness and Residential Stability: The Residential Time-Line Follow-Back Inventory

    ERIC Educational Resources Information Center

    Tsemberis, Sam; McHugo, Gregory; Williams, Valerie; Hanrahan, Patricia; Stefancic, Ana

    2007-01-01

    Reliable and valid longitudinal residential histories are needed to assess interventions to reduce homelessness and increase community tenure. This study examined the test-retest reliability, sensitivity to change, and concurrent validity of the Residential Time-Line Follow-Back (TLFB) Inventory, a method used to record residential histories in…

  16. Multifunctional Magnetoliposomes for Sequential Controlled Release.

    PubMed

    Salvatore, Annalisa; Montis, Costanza; Berti, Debora; Baglioni, Piero

    2016-08-23

    The simultaneous or sequential delivery of multiple therapeutic active principles to a specific target is one of the main challenges of nanomedicine. This goal requires the construction of complex devices often extremely time and cost consuming. Supramolecular self-assemblies, with building blocks of different nature, each providing a specific function to the final construct, can combine a facile synthetic route with a high tunability and structural control. In this study we provide the proof-of-principle of a drug delivery system, DDS, constituted of (i) liposomes, providing a fully biocompatible lipid scaffold suitable to host both hydrophobic and hydrophilic drugs; (ii) a double-stranded DNA conjugated with a cholesteryl unit that spontaneously inserts into the lipid membrane; and (iii) hydrophobic and hydrophilic superparamagnetic iron oxide nanoparticles (SPIONs) embedded inside the lipid membrane of liposomes or connected to the DNA, respectively. Upon application of an alternating magnetic field, the SPIONs can trigger, through thermal activation, the release of a DNA strand or of the liposomal payload, depending on the frequency and the application time of the field, as proved by both steady-state and time-resolved fluorescence studies. This feature is due to the different localization of the two kinds of SPIONS within the construct and demonstrates the feasibility of a multifunctional DDS, built up from self-assembly of biocompatible building blocks. PMID:27504891

  17. Multifunction minimization for programmable logic arrays

    SciTech Connect

    Campbell, J.A.

    1984-01-01

    The problem of minimizing two-level AND/OR Boolean algebraic functions of n inputs and m outputs for implementation on programmable logic arrays (PLA) is examined. The theory of multiple-output functions as well as the historically alternative approaches to reckoning the cost of an equation implementation are reviewed. The PLA is shown to be a realization of the least product gate equation cost criterion. The multi-function minimization is dealt with in the context of a directed tree search algorithm developed in previous research. The PLA oriented minimization is shown to alter the nature of each of the basic tenets of multiple-output minimization used in earlier work. The concept of a non-prime but selectable implicant is introduced. A new cost criterion, the quantum cost, is discussed, and an approximation algorithm utilizing this criterion is developed. A timing analysis of a cyclic resolution algorithm for PLA based functions is presented. Lastly, the question of efficiency in automated minimization algorithms is examined. The application of the PLA cost criterion is shown to exhibit intrinsic increases in computational efficiency. A minterm classification algorithm is suggested and a PLA minimization algorithm is implemented in the FORTRAN language.

  18. Multifunctional Stiff Carbon Foam Derived from Bread.

    PubMed

    Yuan, Ye; Ding, Yujie; Wang, Chunhui; Xu, Fan; Lin, Zaishan; Qin, Yuyang; Li, Ying; Yang, Minglong; He, Xiaodong; Peng, Qingyu; Li, Yibin

    2016-07-01

    The creation of stiff yet multifunctional three-dimensional porous carbon architecture at very low cost is still challenging. In this work, lightweight and stiff carbon foam (CF) with adjustable pore structure was prepared by using flour as the basic element via a simple fermentation and carbonization process. The compressive strength of CF exhibits a high value of 3.6 MPa whereas its density is 0.29 g/cm(3) (compressive modulus can be 121 MPa). The electromagnetic interference (EMI) shielding effectiveness measurements (specific EMI shielding effectiveness can be 78.18 dB·cm(3)·g(-1)) indicate that CF can be used as lightweight, effective shielding material. Unlike ordinary foam structure materials, the low thermal conductivity (lowest is 0.06 W/m·K) with high resistance to fire makes CF a good candidate for commercial thermal insulation material. These results demonstrate a promising method to fabricate an economical, robust carbon material for applications in industry as well as topics regarding environmental protection and improvement of energy efficiency. PMID:27295106

  19. Microstructure Evolution of a Multifunctional Titanium Alloy

    NASA Astrophysics Data System (ADS)

    Tian, Yu Xing; Hao, Yu Lin

    2016-03-01

    To optimize both mechanical and functional properties of multifunctional titanium alloys via grain refinement, an example of such alloys termed as Ti2448 is adopted to investigate its microstructure evolution and strain rate sensitivity by compression in the single β-phase field. The results show that flow stress and strain rate follow a bilinear relation, which is in sharp contrast with other metallic materials exhibiting a monotonic linearity. Below the critical strain of 1 s-1, the alloy has a normal strain rate sensitivity factor of 0.265. Above the critical value, its hardening rate is ultra-low with a factor of 0.03. Inspite of ultra-low hardening, the alloy is plastic stable under the tested conditions. With the aid of electron back-scattering diffraction and transmission electron microscopy analyses, microstructure evolution via several mechanisms such as dynamic recovery and recrystallization is evaluated by quantitative measurements of grain misorientation and its distribution, sub-grain formation, and localized grain refinement. These results are helpful to obtain the homogenous ultrafine-grained alloy by multi-step thermo-mechanical processing.

  20. Angiography with a multifunctional line scanning ophthalmoscope

    NASA Astrophysics Data System (ADS)

    Hammer, Daniel X.; Ferguson, R. Daniel; Patel, Ankit H.; Vazquez, Vanessa; Husain, Deeba

    2012-02-01

    A multifunctional line scanning ophthalmoscope (mLSO) was designed, constructed, and tested on human subjects. The mLSO could sequentially acquire wide-field, confocal, near-infrared reflectance, fluorescein angiography (FA), and indocyanine green angiography (ICGA) retinal images. The system also included a retinal tracker (RT) and a photodynamic therapy laser treatment port. The mLSO was tested in a pilot clinical study on human subjects with and without retinal disease. The instrument exhibited robust retinal tracking and high-contrast line scanning imaging. The FA and ICGA angiograms showed a similar appearance of hyper- and hypo-pigmented disease features and a nearly equivalent resolution of fine capillaries compared to a commercial flood-illumination fundus imager. An mLSO-based platform will enable researchers and clinicians to image human and animal eyes with a variety of modalities and deliver therapeutic beams from a single automated interface. This approach has the potential to improve patient comfort and reduce imaging session times, allowing clinicians to better diagnose, plan, and conduct patient procedures with improved outcomes.

  1. Multifunctional brushes made from carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Cao, Anyuan; Veedu, Vinod P.; Li, Xuesong; Yao, Zhaoling; Ghasemi-Nejhad, Mehrdad N.; Ajayan, Pulickel M.

    2005-07-01

    Brushes are common tools for use in industry and our daily life, performing a variety of tasks such as cleaning, scraping, applying and electrical contacts. Typical materials for constructing brush bristles include animal hairs, synthetic polymer fibres and metal wires (see, for example, ref. 1). The performance of these bristles has been limited by the oxidation and degradation of metal wires, poor strength of natural hairs, and low thermal stability of synthetic fibres. Carbon nanotubes, having a typical one-dimensional nanostructure, have excellent mechanical properties, such as high modulus and strength, high elasticity and resilience, thermal conductivity and large surface area (50-200 m2 g-1). Here we construct multifunctional, conductive brushes with carbon nanotube bristles grafted on fibre handles, and demonstrate their several unique tasks such as cleaning of nanoparticles from narrow spaces, coating of the inside of holes, selective chemical adsorption, and as movable electromechanical brush contacts and switches. The nanotube bristles can also be chemically functionalized for selective removal of heavy metal ions.

  2. Ionic liquid based multifunctional double network gel

    NASA Astrophysics Data System (ADS)

    Ahmed, Kumkum; Higashihara, Tomoya; Arafune, Hiroyuki; Kamijo, Toshio; Morinaga, Takashi; Sato, Takaya; Furukawa, Hidemitsu

    2015-04-01

    Gels are a promising class of soft and wet materials with diverse application in tissue engineering and bio-medical purpose. In order to accelerate the development of gels, it is required to synthesize multi-functional gels of high mechanical strength, ultra low surface friction and suitable elastic modulus with a variety of methods and new materials. Among many types of gel ionic gel made from ionic liquids (ILs) could be used for diverse applications in electrochemical devices and in the field of tribology. IL, a promising materials for lubrication, is a salt with a melting point lower than 100 °C. As a lubricant, ILs are characterized by an extremely low vapor pressure, high thermal stability and high ion conductivity. In this work a novel approach of making double network DN ionic gel using IL has been made utilizing photo polymerization process. A hydrophobic monomer Methyl methacrylate (MMA) has been used as a first network and a hydrophobic IL monomer, N,N-diethyl-N-(2-mthacryloylethyl)-N-methylammonium bistrifluoromethylsulfonyl)imide (DEMM-TFSI) has been used as a second network using photo initiator benzophenon and crosslinker triethylene glycol dimethacrylate (TEGDMA). The resulting DN ionic gel shows transparency, flexibility, high thermal stability, good mechanical toughness and low friction coefficient value which can be a potential candidate as a gel slider in different mechanical devices and can open a new area in the field of gel tribology.

  3. Nucleolin: a multifunctional major nucleolar phosphoprotein.

    PubMed

    Tuteja, R; Tuteja, N

    1998-01-01

    Nucleolin is a major protein of exponentially growing eukaryotic cells where it is present in abundance at the heart of the nucleolus. It is highly conserved during evolution. Nucleolin contains a specific bipartite nuclear localization signal sequence and possesses a number of unusual structural features. It has unique tripartite structure and each domain performs a specific function by interacting with DNA or RNA or proteins. Nucleolin exhibits intrinsic self-cleaving, DNA helicase, RNA helicase and DNA-dependent ATPase activities. Nucleolin also acts as a sequence-specific RNA binding protein, an autoantigen, and as the component of a B cell specific transcription factor. Its phosphorylation by cdc2, CK2, and PKC-zeta modulate some of its activities. This multifunctional protein has been implicated to be involved directly or indirectly in many metabolic processes such as ribosome biogenesis (which includes rDNA transcription, pre-rRNA synthesis, rRNA processing, ribosomal assembly and maturation), cytokinesis, nucleogenesis, cell proliferation and growth, cytoplasmic-nucleolar transport of ribosomal components, transcriptional repression, replication, signal transduction, inducing chromatin decondensation and many more (see text). In plants it is developmentally, cell-cycle, and light regulated. The regulation of all these functions of a single protein seems to be a challenging puzzle. PMID:9918513

  4. Surface-modified multifunctional MIP nanoparticles

    PubMed Central

    Moczko, Ewa; Poma, Alessandro; Guerreiro, Antonio; de Vargas Sansalvador, Isabel Perez; Caygill, Sarah; Canfarotta, Francesco; Whitcombe, Michael J.; Piletsky, Sergey

    2015-01-01

    The synthesis of core-shell molecularly imprinted polymer nanoparticles (MIP NPs) has been performed using a novel solid-phase approach on immobilised templates. The same solid phase also acts as protective functionality for high affinity binding sites during subsequent derivatisation/shell formation. This procedure allows for the rapid synthesis, controlled separation and purification of high-affinity materials, with each production cycle taking just 2 hours. The aim of this approach is to synthesise uniformly-sized imprinted materials at the nanoscale which can be readily grafted with various polymers without affecting their affinity and specificity. For demonstration purposes we grafted anti-melamine MIP NPs with coatings which introduce the following surface characteristics: high polarity (PEG methacrylate); electro-activity (vinyl ferrocene); fluorescence (eosin acrylate); thiol groups (pentaerythritol tetrakis(3-mercaptopropionate)). The method has broad applicability and can be used to produce multifunctional imprinted nanoparticles with potential for further application in the biosensors, diagnostics and biomedical fields and as an alternative to natural receptors. PMID:23503559

  5. Microstructure Evolution of a Multifunctional Titanium Alloy

    NASA Astrophysics Data System (ADS)

    Tian, Yu Xing; Hao, Yu Lin

    2016-06-01

    To optimize both mechanical and functional properties of multifunctional titanium alloys via grain refinement, an example of such alloys termed as Ti2448 is adopted to investigate its microstructure evolution and strain rate sensitivity by compression in the single β-phase field. The results show that flow stress and strain rate follow a bilinear relation, which is in sharp contrast with other metallic materials exhibiting a monotonic linearity. Below the critical strain of 1 s-1, the alloy has a normal strain rate sensitivity factor of 0.265. Above the critical value, its hardening rate is ultra-low with a factor of 0.03. Inspite of ultra-low hardening, the alloy is plastic stable under the tested conditions. With the aid of electron back-scattering diffraction and transmission electron microscopy analyses, microstructure evolution via several mechanisms such as dynamic recovery and recrystallization is evaluated by quantitative measurements of grain misorientation and its distribution, sub-grain formation, and localized grain refinement. These results are helpful to obtain the homogenous ultrafine-grained alloy by multi-step thermo-mechanical processing.

  6. Multifunctional magnetoelectric materials for device applications

    NASA Astrophysics Data System (ADS)

    Ortega, N.; Kumar, Ashok; Scott, J. F.; Katiyar, Ram S.

    2015-12-01

    Over the past decade magnetoelectric (ME) mutiferroic (MF) materials and their devices are one of the highest priority research topics that has been investigated by the scientific ferroics community to develop the next generation of novel multifunctional materials. These systems show the simultaneous existence of two or more ferroic orders, and cross-coupling between them, such as magnetic spin, polarisation, ferroelastic ordering, and ferrotoroidicity. Based on the type of ordering and coupling, they have drawn increasing interest for a variety of device applications, such as magnetic field sensors, nonvolatile memory elements, ferroelectric photovoltaics, nano-electronics etc. Since single-phase materials exist rarely in nature with strong cross-coupling properties, intensive research activity is being pursued towards the discovery of new single-phase multiferroic materials and the design of new engineered materials with strong magneto-electric (ME) coupling. This review article summarises the development of different kinds of multiferroic material: single-phase and composite ceramic, laminated composite and nanostructured thin films. Thin-film nanostructures have higher magnitude direct ME coupling values and clear evidence of indirect ME coupling compared with bulk materials. Promising ME coupling coefficients have been reported in laminated composite materials in which the signal to noise ratio is good for device fabrication. We describe the possible applications of these materials.

  7. Multifunctional Deployment Hinges Rigidified by Ultraviolet

    NASA Technical Reports Server (NTRS)

    Kerslake, Thomas W.; Simburger, Edward J.; Matusmoto, James; Giants, Thomas W.; Garcia, Alexander; Perry, Alan; Rawal, Suraj; Marshall, Craig; Lin, John Kun Hung; Day, Jonathan Robert; Scarborough, Stephen Emerson

    2005-01-01

    Multifunctional hinges have been developed for deploying and electrically connecting panels comprising planar arrays of thin-film solar photovoltaic cells. In the original intended application of these hinges, the panels would be facets of a 32-sided (and approximately spherical) polyhedral microsatellite (see figure), denoted a PowerSphere, that would be delivered to orbit in a compact folded configuration, then deployed by expansion of gas in inflation bladders. Once deployment was complete, the hinges would be rigidified to provide structural connections that would hold the panels in their assigned relative positions without backlash. Such hinges could also be used on Earth for electrically connecting and structurally supporting solar panels that are similarly shipped in compact form and deployed at their destinations. As shown in section A-A in the figure, a hinge of this type is partly integrated with an inflation bladder and partly integrated with the frame of a solar panel. During assembly of the hinge, strip extensions from a flexible circuit harness on the bladder are connected to corresponding thin-film conductors on the solar panel by use of laser welding and wrap-around contacts. The main structural component of the hinge is a layer of glass fiber impregnated with an ultraviolet-curable resin. After deployment, exposure to ultraviolet light from the Sun cures the resin, thereby rigidifying the hinge.

  8. Development of multifunctional shape memory polymer foams

    NASA Astrophysics Data System (ADS)

    Song, Janice J.; Srivastava, Ijya; Naguib, Hani E.

    2015-05-01

    Shape memory polymers (SMP) are a class of stimuli-responsive materials which are able to respond to external stimulus such as temperature and deformation by changing their shape, and return to their original shape upon reversal or removal of the external stimulus. Although SMP materials have been studied extensively and have been used in a wide range of applications such as medicine, aerospace, and robotics, only few studies have looked at the potential of designing multifunctional SMP foams and blends. In this study, we investigate the feasibility of a design of SMP foam materials and blends. The actuator construct will contain a core SMP epoxy and blend of polylactic acid and polyurethane. The effects of the processing parameters of shape memory polymer (SMP) foams on the shape memory effect (SME) were investigated. The solid state foaming technique was employed to obtain the desired foamed cellular structure. One particular point of interest is to understand how the processing parameters affect the SMP and its glass transition temperature (Tg). By correctly tailoring these parameters it is possible to modify the SMP to have an improved shape memory effect SME.

  9. "Smart" Multifunctional Polymers for Enhanced Oil Recovery

    SciTech Connect

    Charles McCormick; Andrew Lowe

    2005-10-15

    Herein we report the synthesis and solution characterization of a novel series of AB diblock copolymers with neutral, water-soluble A blocks comprised of N,N-dimethylacrylamide (DMA) and pH-responsive B blocks of N,N-dimethylvinylbenzylamine (DMVBA). To our knowledge, this represents the first example of an acrylamido-styrenic block copolymer prepared directly in homogeneous aqueous solution. The best blocking order (using polyDMA as a macro-CTA) was shown to yield well-defined block copolymers with minimal homopolymer impurity. Reversible aggregation of these block copolymers in aqueous media was studied by {sup 1}H NMR spectroscopy and dynamic light scattering. Finally, an example of core-crosslinked micelles was demonstrated by the addition of a difunctional crosslinking agent to a micellar solution of the parent block copolymer. Our ability to form micelles directly in water that are responsive to pH represents an important milestone in developing ''smart'' multifunctional polymers that have potential for oil mobilization in Enhanced Oil Recovery Processes.

  10. "Smart" Multifunctional Polymers for Enhanced Oil Recovery

    SciTech Connect

    Charles McCormick; Andrew Lowe

    2007-03-20

    Recent recommendations made by the Department of Energy, in conjunction with ongoing research at the University of Southern Mississippi, have signified a need for the development of 'smart' multi-functional polymers (SMFPs) for Enhanced Oil Recovery (EOR) processes. Herein we summarize research from the period of September 2003 through March 2007 focusing on both Type I and Type II SMFPs. We have demonstrated the synthesis and behavior of materials that can respond in situ to stimuli (ionic strength, pH, temperature, and shear stress). In particular, Type I SMFPs reversibly form micelles in water and have the potential to be utilized in applications that serve to lower interfacial tension at the oil/water interface, resulting in emulsification of oil. Type II SMFPs, which consist of high molecular weight polymers, have been synthesized and have prospective applications related to the modification of fluid viscosity during the recovery process. Through the utilization of these advanced 'smart' polymers, the ability to recover more of the original oil in place and a larger portion of that by-passed or deemed 'unrecoverable' by conventional chemical flooding should be possible.

  11. Angiography with a multifunctional line scanning ophthalmoscope

    PubMed Central

    Ferguson, R. Daniel; Patel, Ankit H.; Vazquez, Vanessa; Husain, Deeba

    2012-01-01

    Abstract. A multifunctional line scanning ophthalmoscope (mLSO) was designed, constructed, and tested on human subjects. The mLSO could sequentially acquire wide-field, confocal, near-infrared reflectance, fluorescein angiography (FA), and indocyanine green angiography (ICGA) retinal images. The system also included a retinal tracker (RT) and a photodynamic therapy laser treatment port. The mLSO was tested in a pilot clinical study on human subjects with and without retinal disease. The instrument exhibited robust retinal tracking and high-contrast line scanning imaging. The FA and ICGA angiograms showed a similar appearance of hyper- and hypo-pigmented disease features and a nearly equivalent resolution of fine capillaries compared to a commercial flood-illumination fundus imager. An mLSO-based platform will enable researchers and clinicians to image human and animal eyes with a variety of modalities and deliver therapeutic beams from a single automated interface. This approach has the potential to improve patient comfort and reduce imaging session times, allowing clinicians to better diagnose, plan, and conduct patient procedures with improved outcomes. PMID:22463040

  12. The tight junction: a multifunctional complex.

    PubMed

    Schneeberger, Eveline E; Lynch, Robert D

    2004-06-01

    Multicellular organisms are separated from the external environment by a layer of epithelial cells whose integrity is maintained by intercellular junctional complexes composed of tight junctions, adherens junctions, and desmosomes, whereas gap junctions provide for intercellular communication. The aim of this review is to present an updated overview of recent developments in the area of tight junction biology. In a relatively short time, our knowledge of the tight junction has evolved from a relatively simple view of it being a permeability barrier in the paracellular space and a fence in the plane of the plasma membrane to one of it acting as a multicomponent, multifunctional complex that is involved in regulating numerous and diverse cell functions. A group of integral membrane proteins-occludin, claudins, and junction adhesion molecules-interact with an increasingly complex array of tight junction plaque proteins not only to regulate paracellular solute and water flux but also to integrate such diverse processes as gene transcription, tumor suppression, cell proliferation, and cell polarity. PMID:15151915

  13. Multifunctional aliphatic polyester nanofibers for tissue engineering.

    PubMed

    Zhan, Jianan; Singh, Anirudha; Zhang, Zhe; Huang, Ling; Elisseeff, Jennifer H

    2012-01-01

    Electrospun fibers based on aliphatic polyesters, such as poly(ε-caprolactone) (PCL), have been widely used in regenerative medicine and drug delivery applications due to their biocompatibility, low cost and ease of fabrication. However, these aliphatic polyester fibers are hydrophobic in nature, resulting in poor wettability, and they lack functional groups for decorating the scaffold with chemical and biological cues. Current strategies employed to overcome these challenges include coating and blending the fibers with bioactive components or chemically modifying the fibers with plasma treatment and reactants. In the present study, we report on designing multifunctional electrospun nanofibers based on the inclusion complex of PCL-α-cyclodextrin (PCL-α-CD), which provides both structural support and multiple functionalities for further conjugation of bioactive components. This strategy is independent of any chemical modification of the PCL main chain, and electrospinning of PCL-α-CD is as easy as electrospinning PCL. Here, we describe synthesis of the PCL-α-CD electrospun nanofibers, elucidate composition and structure, and demonstrate the utility of functional groups on the fibers by conjugating a fluorescent small molecule and a polymeric-nanobead to the nanofibers. Furthermore, we demonstrate the application of PCL-α-CD nanofibers for promoting osteogenic differentiation of human adipose-derived stem cells (hADSCs), which induced a higher level of expression of osteogenic markers and enhanced production of extracellular matrix (ECM) proteins or molecules compared with control PCL fibers. PMID:23507886

  14. Integrated residential photovoltaic array development

    NASA Technical Reports Server (NTRS)

    Shepard, N. F., Jr.

    1981-01-01

    The design details of an optimized integrated residential photovoltaic module/array are presented. This selected design features a waterproofing and mounting scheme which was devised to simplify the installation procedures by the avoidance of complex gasketed or caulked joints, while still maintaining a high confidence that the watertight integrity of the integral roofing surface will be achieved for the design lifetime of the system. The production and installation costs for the selected module/array design are reported for a range of annual production rates as a function of the cost of solar cells.

  15. Chapter 17: Residential Behavior Protocol

    SciTech Connect

    Stewart, J.; Todd, A.

    2015-01-01

    Residential behavior-based (BB) programs use strategies grounded in the behavioral social sciences to influence household energy use. Strategies may include providing households with real-time or delayed feedback about their energy use; supplying energy-efficiency education and tips; rewarding households for reducing their energy use; comparing households to their peers; and establishing games, tournaments, and competitions. BB programs often target multiple energy end uses and encourage energy savings, demand savings, or both. Savings from BB programs are usually a small percentage of energy use, typically less than 5%.

  16. Credit Scores, Race, and Residential Sorting

    ERIC Educational Resources Information Center

    Nelson, Ashlyn Aiko

    2010-01-01

    Credit scores have a profound impact on home purchasing power and mortgage pricing, yet little is known about how credit scores influence households' residential location decisions. This study estimates the effects of credit scores on residential sorting behavior using a novel mortgage industry data set combining household demographic, credit, and…

  17. An Analysis of the Residential Remodeling Occupation.

    ERIC Educational Resources Information Center

    Scruggs, Kenneth

    The general purpose of the occupational analysis is to provide workable, basic information dealing with the many and varied duties performed in the residential remodeling occupation. The analysis only briefly covers the many areas of residential remodeling. The document opens with a brief introduction followed by a job description. The bulk of the…

  18. Residential Wood Combustion Emissions and Safety Guidebook.

    ERIC Educational Resources Information Center

    Becker, Mimi, Ed.; Barnett, Lucy, Ed.

    This seven-part guidebook provides information to assist decision makers and other individuals involved in the residential wood energy fuel cycle. It can be used as a tool for designing or implementing programs, strategies, and policies that encourage, prevent, or mitigate safety or air emission related impacts of residential woodburning equipment…

  19. An Analysis of the Residential Electricity Occupation.

    ERIC Educational Resources Information Center

    Dearth, Charles E.; Nordvig, Carl A.

    The general purpose of the occupational analysis is to provide workable, basic information dealing with the many and varied duties performed in the residential electricity occupation. It does not cover the complete work of a master electrician, only the basic skills needed to do residential wiring. The document opens with a brief introduction…

  20. RESIDENTIAL CONSTRUCTION CODE IMPACTS ON RADON

    EPA Science Inventory

    The paper discusses residential construction code impacts on radon. It references existing residential construction codes that pertain to the elements of construction that impact either the ability to seal radon out of houses or the ability to achieve good soil ventilation for ra...

  1. Troubleshooting the residential air conditioning system

    SciTech Connect

    Puzio, H.

    1996-01-01

    In order to effectively diagnose problems in a residential air conditioning system, the technician should develop and follow a logical step-by-step troubleshooting procedure. A list of problems, along with possible causes and solutions, that a technician may encounter when servicing a residential air conditioner is presented.

  2. ANALYSIS OF RESIDENTIAL COAL STOVE EMISSIONS

    EPA Science Inventory

    The report gives results of an evaluation, in cooperation with the State of Vermont's Agency of Environmental Conservation, of emissions generated by anthracite and bituminous coal used for residential heating. A residential coal stove was operated with both coals, while comparin...

  3. Transport improvement, commuting costs, and residential location

    NASA Technical Reports Server (NTRS)

    Stucker, J. P.

    1973-01-01

    A theoretical framework for evaluating the effects of introducing new transportation on residential travel patterns is presented. Data are based on changes in residential location of urban commuters that alter the mode and length of work trips as well as economic factors.

  4. A Revaluation of Indexes of Residential Segregation

    ERIC Educational Resources Information Center

    Winship, Christopher

    1977-01-01

    Shows that there are at least two different perspectives from which residential segregation can be examined. Segregation can be measured as it deviates from a situation of complete desegregation or in terms of a situation in which there is random segregation in the city. New criteria for indexes of residential segregation are developed. (Author/JM)

  5. School Segregation, Residential Segregation: Some Speculation.

    ERIC Educational Resources Information Center

    Kantrowitz, Nathan

    This essay addressed the question of to what extent does school segregation and school desegregation policy shape residential segregation. Census data, ethnic segregation, voluntary self-segregation, and attitude surveys are discussed in the residential segregation section. The Wolf and Lebeaux study is critically appraised in reference to school…

  6. Residential Segregation: Challenge to White America.

    ERIC Educational Resources Information Center

    Denton, Nancy A.

    1994-01-01

    Examines the problem of residential segregation and demonstrates that it is a problem of social structure. The author contends that residential segregation has affirmed the continued subordination of blacks in American society over the past 50 years. New leadership in the Department of Housing and Urban Development is viewed as a positive…

  7. 78 FR 32124 - Community Residential Care

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ... approval is revoked. On May 13, 1996, 61 FR 21965, VA redesignated Sec. 17.51n as Sec. 17.67. We are... AFFAIRS 38 CFR Part 17 RIN 2900-AO62 Community Residential Care AGENCY: Department of Veterans Affairs... concerning approval of non-VA community residential care facilities to allow VA to waive such...

  8. Residential Differences in Cohabitors' Union Transitions

    ERIC Educational Resources Information Center

    Brown, Susan L.; Snyder, Anastasia R.

    2006-01-01

    Using data from the 1995 National Survey of Family Growth, we examine residential variation in cohabiting women's union outcomes. Prior work has shown that although there are no residential differences in cohabitation, nonmetro women are more likely than others to marry directly and hold more favorable attitudes toward marriage. Building on this…

  9. Children with ADHD in Residential Care

    ERIC Educational Resources Information Center

    Casey, Kathryn J.; Hagaman, Jessica L.; Trout, Alexandra L.; Reid, Robert; Chmelka, Beth; Thompson, Ronald W.; Daly, Daniel L.

    2008-01-01

    Little is known about the characteristics or functioning of children with ADHD in residential care as compared to their non-ADHD peers. This study evaluated data on 538 children with (n = 125) and without (n = 413) ADHD in residential care to determine demographic, mental health, behavioral, and treatment (i.e., medication use) characteristics.…

  10. Laparoscopic Multifunctional Instruments: Design and Testing of Initial Prototypes

    PubMed Central

    Schadler, Jeremy; Haluck, Randy S.; Culkar, Kristin; Dziedzic, Ryan

    2005-01-01

    Background: Advances in minimally invasive surgical techniques will require new types of instrument end-effectors for smaller, longer, and flexible instruments. These include a new class of multifunctional instruments capable of performing more than 1 task with a single set of working jaws. Furthermore, it is desired that multifunctional instruments be designed to provide improved dexterity compared with that in currently commercially available instruments. Methods: Three prototypes of multifunctional laparoscopic surgical instruments are described: (1) a mechanical scissors-grasper, (2) a mechanical scissors-grasper-articulator, and (3) a compliant mechanism scissors-grasper. Methods of baseline analysis, design methods and considerations, and subjective evaluations of interim prototypes are presented. Results: The 3 prototypes demonstrate promising early results. However, based on subjective evaluation, these prototypes do not perform individual functions as well as basic disposable single-function laparoscopic instruments do. Conclusions: The concept of multifunctionality and increased end-effector dexterity is achievable as demonstrated by the prototypes presented. Further work is required to refine, simplify, and improve the multifunctional instruments to a point where they may be useful as surgical tools. PMID:15791983

  11. Residential ventilation standards scoping study

    SciTech Connect

    McKone, Thomas E.; Sherman, Max H.

    2003-10-01

    The goals of this scoping study are to identify research needed to develop improved ventilation standards for California's Title 24 Building Energy Efficiency Standards. The 2008 Title 24 Standards are the primary target for the outcome of this research, but this scoping study is not limited to that timeframe. We prepared this scoping study to provide the California Energy Commission with broad and flexible options for developing a research plan to advance the standards. This document presents the findings of a scoping study commissioned by the Public Interest Energy Research (PIER) program of the California Energy Commission to determine what research is necessary to develop new residential ventilation requirements for California. This study is one of three companion efforts needed to complete the job of determining the ventilation needs of California residences, determining the bases for setting residential ventilation requirements, and determining appropriate ventilation technologies to meet these needs and requirements in an energy efficient manner. Rather than providing research results, this scoping study identifies important research questions along with the level of effort necessary to address these questions and the costs, risks, and benefits of pursuing alternative research questions. In approaching these questions and corresponding levels of effort, feasibility and timing were important considerations. The Commission has specified Summer 2005 as the latest date for completing this research in time to update the 2008 version of California's Energy Code (Title 24).

  12. Residential photovoltaic module and array requirements study

    NASA Technical Reports Server (NTRS)

    Nearhoof, S. L.; Oster, J. R.

    1979-01-01

    Design requirements for photovoltaic modules and arrays used in residential applications were identified. Building codes and referenced standards were reviewed for their applicability to residential photovoltaic array installations. Four installation types were identified - integral (replaces roofing), direct (mounted on top of roofing), stand-off (mounted away from roofing), and rack (for flat or low slope roofs, or ground mounted). Installation costs were developed for these mounting types as a function of panel/module size. Studies were performed to identify optimum module shapes and sizes and operating voltage cost drivers. It is concluded that there are no perceived major obstacles to the use of photovoltaic modules in residential arrays. However, there is no applicable building code category for residential photovoltaic modules and arrays and additional work with standards writing organizations is needed to develop residential module and array requirements.

  13. Multifunctional PEGylated nanoclusters for biomedical applications

    NASA Astrophysics Data System (ADS)

    Peng, Erwin; Choo, Eugene Shi Guang; Tan, Cherie Shi Hua; Tang, Xiaosheng; Sheng, Yang; Xue, Junmin

    2013-06-01

    A simple and versatile synthesis method to form water soluble multifunctional nanoclusters using polyethylene glycol (PEG) functionalized poly(maleic anhydride-alt-1-octadecene) amphiphilic brush copolymers (PMAO-g-PEG) was presented. Simply by tuning the core size and the initial nanocrystal concentration, manganese ferrite nanoparticles (MFNPs) were used to demonstrate the versatility of tuning the loading amount of the nanoclusters. The resultant nanoclusters were found to have a well-controlled spherical shape. When Zn-doped AgInS2 quantum dots (AIZS QDs) were loaded together with the MFNP nanocrystals, bi-functional nanoclusters with fluorescent and magnetic behaviors were obtained. Such bi-functional nanoclusters were also successfully demonstrated for cellular bio-imaging. Moreover, the presence of another type of nanocrystals together with MFNPs was found to have a negligible effect on the overall properties of the nanoclusters as demonstrated by the MR relaxivity test. From the time-dependent colloidal stability test, it was found that the presence of the PEG chain grafted onto PMAO was able to reduce protein adsorption onto the nanocluster surface. An in vitro study on NIH/3T3 demonstrated the biocompatibility of the nanoclusters. Such biocompatible and colloidally stable nanoclusters with an approximate size of 80-120 nm were suitable for both MRI and cell labeling applications.A simple and versatile synthesis method to form water soluble multifunctional nanoclusters using polyethylene glycol (PEG) functionalized poly(maleic anhydride-alt-1-octadecene) amphiphilic brush copolymers (PMAO-g-PEG) was presented. Simply by tuning the core size and the initial nanocrystal concentration, manganese ferrite nanoparticles (MFNPs) were used to demonstrate the versatility of tuning the loading amount of the nanoclusters. The resultant nanoclusters were found to have a well-controlled spherical shape. When Zn-doped AgInS2 quantum dots (AIZS QDs) were loaded together

  14. Targeting Strategies for Multifunctional Nanoparticles in Cancer Imaging and Therapy

    PubMed Central

    Yu, Mi Kyung; Park, Jinho; Jon, Sangyong

    2012-01-01

    Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions including targeting, imaging, therapy, and etc have been intensively studied aiming to overcome limitations associated with conventional cancer diagnosis and therapy. Of various nanoparticles, magnetic iron oxide nanoparticles with superparamagnetic property have shown potential as multifunctional nanoparticles for clinical translation because they have been used asmagnetic resonance imaging (MRI) constrast agents in clinic and their features could be easily tailored by including targeting moieties, fluorescence dyes, or therapeutic agents. This review summarizes targeting strategies for construction of multifunctional nanoparticles including magnetic nanoparticles-based theranostic systems, and the various surface engineering strategies of nanoparticles for in vivo applications. PMID:22272217

  15. Advances in process intensification through multifunctional reactor engineering

    SciTech Connect

    O'Hern, T. J.

    2012-03-01

    This project was designed to advance the art of process intensification leading to a new generation of multifunctional chemical reactors. Experimental testing was performed in order to fully characterize the hydrodynamic operating regimes critical to process intensification and implementation in commercial applications. Physics of the heat and mass transfer and chemical kinetics and how these processes are ultimately scaled were investigated. Specifically, we progressed the knowledge and tools required to scale a multifunctional reactor for acid-catalyzed C4 paraffin/olefin alkylation to industrial dimensions. Understanding such process intensification strategies is crucial to improving the energy efficiency and profitability of multifunctional reactors, resulting in a projected energy savings of 100 trillion BTU/yr by 2020 and a substantial reduction in the accompanying emissions.

  16. Material selection for Multi-Function Waste Tank Facility tanks

    SciTech Connect

    Larrick, A.P.; Blackburn, L.D.; Brehm, W.F.; Carlos, W.C.; Hauptmann, J.P.; Danielson, M.J.; Westerman, R.E.; Divine, J.R.; Foster, G.M.

    1995-03-01

    This paper briefly summarizes the history of the materials selection for the US Department of Energy`s high-level waste carbon steel storage tanks. It also provides an evaluation of the materials for the construction of new tanks at the evaluation of the materials for the construction of new tanks at the Multi-Function Waste Tank Facility. The evaluation included a materials matrix that summarized the critical design, fabrication, construction, and corrosion resistance requirements: assessed. each requirement: and cataloged the advantages and disadvantages of each material. This evaluation is based on the mission of the Multi-Function Waste Tank Facility. On the basis of the compositions of the wastes stored in Hanford waste tanks, it is recommended that tanks for the Multi-Function Waste Tank Facility be constructed of ASME SA 515, Grade 70, carbon steel.

  17. Advances in Process Intensification through Multifunctional Reactor Engineering

    SciTech Connect

    O'Hern, Timothy; Evans, Lindsay; Miller, Jim; Cooper, Marcia; Torczynski, John; Pena, Donovan; Gill, Walt

    2011-02-01

    This project was designed to advance the art of process intensification leading to a new generation of multifunctional chemical reactors utilizing pulse flow. Experimental testing was performed in order to fully characterize the hydrodynamic operating regimes associated with pulse flow for implementation in commercial applications. Sandia National Laboratories (SNL) operated a pilot-scale multifunctional reactor experiment for operation with and investigation of pulse flow operation. Validation-quality data sets of the fluid dynamics, heat and mass transfer, and chemical kinetics were acquired and shared with Chemical Research and Licensing (CR&L). Experiments in a two-phase air-water system examined the effects of bead diameter in the packing, and viscosity. Pressure signals were used to detect pulsing. Three-phase experiments used immiscible organic and aqueous liquids, and air or nitrogen as the gas phase. Hydrodynamic studies of flow regimes and holdup were performed for different types of packing, and mass transfer measurements were performed for a woven packing. These studies substantiated the improvements in mass transfer anticipated for pulse flow in multifunctional reactors for the acid-catalyzed C4 paraffin/olefin alkylation process. CR&L developed packings for this alkylation process, utilizing their alkylation process pilot facilities in Pasadena, TX. These packings were evaluated in the pilot-scale multifunctional reactor experiments established by Sandia to develop a more fundamental understanding of their role in process intensification. Lummus utilized the alkylation technology developed by CR&L to design and optimize the full commercial process utilizing multifunctional reactors containing the packings developed by CR&L and evaluated by Sandia. This hydrodynamic information has been developed for multifunctional chemical reactors utilizing pulse flow, for the acid-catalyzed C4 paraffin/olefin alkylation process, and is now accessible for use in

  18. Advances in Process Intensification through Multifunctional Reactor Engineering

    SciTech Connect

    O'Hern, Timothy; Evans, Lindsay; Miller, Jim; Cooper, Marcia; Torczynski, John; Pena, Donovan; Gill, Walt; Groten, Will; Judzis, Arvids; Foley, Richard; Smith, Larry; Cross, Will; Vogt, T.

    2011-06-27

    This project was designed to advance the art of process intensification leading to a new generation of multifunctional chemical reactors utilizing pulse flow. Experimental testing was performed in order to fully characterize the hydrodynamic operating regimes associated with pulse flow for implementation in commercial applications. Sandia National Laboratories (SNL) operated a pilot-scale multifunctional reactor experiment for operation with and investigation of pulse flow operation. Validation-quality data sets of the fluid dynamics, heat and mass transfer, and chemical kinetics were acquired and shared with Chemical Research and Licensing (CR&L). Experiments in a two-phase air-water system examined the effects of bead diameter in the packing, and viscosity. Pressure signals were used to detect pulsing. Three-phase experiments used immiscible organic and aqueous liquids, and air or nitrogen as the gas phase. Hydrodynamic studies of flow regimes and holdup were performed for different types of packing, and mass transfer measurements were performed for a woven packing. These studies substantiated the improvements in mass transfer anticipated for pulse flow in multifunctional reactors for the acid-catalyzed C4 paraffin/olefin alkylation process. CR&L developed packings for this alkylation process, utilizing their alkylation process pilot facilities in Pasadena, TX. These packings were evaluated in the pilot-scale multifunctional reactor experiments established by Sandia to develop a more fundamental understanding of their role in process intensification. Lummus utilized the alkylation technology developed by CR&L to design and optimize the full commercial process utilizing multifunctional reactors containing the packings developed by CR&L and evaluated by Sandia. This hydrodynamic information has been developed for multifunctional chemical reactors utilizing pulse flow, for the acid-catalyzed C4 paraffin/olefin alkylation process, and is now accessible for use in

  19. Multifunctional mesoporous silica nanocomposite nanoparticles for theranostic applications.

    PubMed

    Lee, Ji Eun; Lee, Nohyun; Kim, Taeho; Kim, Jaeyun; Hyeon, Taeghwan

    2011-10-18

    Clever combinations of different types of functional nanostructured materials will enable the development of multifunctional nanomedical platforms for multimodal imaging or simultaneous diagnosis and therapy. Mesoporous silica nanoparticles (MSNs) possess unique structural features such as their large surface areas, tunable nanometer-scale pore sizes, and well-defined surface properties. Therefore, they are ideal platforms for constructing multifunctional materials that incorporate a variety of functional nanostructured materials. In this Account, we discuss recent progress by our group and other researchers in the design and fabrication of multifunctional nanocomposite nanoparticles based on mesoporous silica nanostructures for applications to simultaneous diagnosis and therapy. Versatile mesoporous silica-based nanocomposite nanoparticles were fabricated using various methods. Here, we highlight two synthetic approaches: the encapsulation of functional nanoparticles within a mesoporous silica shell and the assembly of nanoparticles on the surface of silica nanostructures. Various nanoparticles were encapsulated in MSNs using surfactants as both phase transfer agents and pore-generating templates. Using MSNs as a scaffold, functional components such as magnetic nanoparticles and fluorescent dyes have been integrated within these systems to generate multifunctional nanocomposite systems that maintain their individual functional characteristics. For example, uniform mesoporous dye-doped silica nanoparticles immobilized with multiple magnetite nanocrystals on their surfaces have been fabricated for their use as a vehicle capable of simultaneous magnetic resonance (MR) and fluorescence imaging and drug delivery. The resulting nanoparticle-incorporated MSNs were then tested in mice with tumors. These in vivo experiments revealed that these multifunctional nanocomposite nanoparticles were delivered to the tumor sites via passive targeting. These nanocomposite

  20. Multi-Function Gas Fired Heat Pump

    SciTech Connect

    Abu-Heiba, Ahmad; Vineyard, Edward Allan

    2015-11-30

    The aim of this project was to design a residential fuel fired heat pump and further improve efficiency in collaboration with an industry partner – Southwest Gas, the developer of the Nextaire commercial rooftop fuel-fired heat pump. Work started in late 2010. After extensive search for suitable engines, one manufactured by Marathon was selected. Several prototypes were designed and built over the following four years. Design changes were focused on lowering the cost of components and the cost of manufacturing. The design evolved to a final one that yielded the lowest cost. The final design also incorporates noise and vibration reduction measures that were verified to be effective through a customer survey. ETL certification is currently (as of November 2015) underway. Southwest Gas is currently in talks with GTI to reach an agreement through which GTI will assess the commercial viability and potential of the heat pump. Southwest Gas is searching for investors to manufacture the heat pump and introduce it to the market.

  1. Multifunctional Inorganic Nanoparticles for Imaging, Targeting, and Drug Delivery

    PubMed Central

    Liong, Monty; Lu, Jie; Kovochich, Michael; Xia, Tian; Ruehm, Stefan G.; Nel, Andre E.; Tamanoi, Fuyuhiko; Zink, Jeffrey I.

    2009-01-01

    Drug delivery, magnetic resonance and fluorescence imaging, magnetic manipulation, and cell targeting are simultaneously possible using a multifunctional mesoporous silica nanoparticle. Superparamagnetic iron oxide nanocrystals were encapsulated inside mesostructured silica spheres that were labeled with fluorescent dye molecules and coated with hydrophilic groups to prevent aggregation. Water-insoluble anticancer drugs were delivered into human cancer cells; surface conjugation with cancer-specific targeting agents increased the uptake into cancer cells relative to that in non-cancerous fibroblasts. The highly versatile multifunctional nanoparticles could potentially be used for simultaneous imaging and therapeutic applications. PMID:19206485

  2. Three-dimensional multifunctional optical coherence tomography for skin imaging

    NASA Astrophysics Data System (ADS)

    Li, En; Makita, Shuichi; Hong, Young-Joo; Kasaragod, Deepa; Sasaoka, Tomoko; Yamanari, Masahiro; Sugiyama, Satoshi; Yasuno, Yoshiaki

    2016-02-01

    Optical coherence tomography (OCT) visualizes cross-sectional microstructures of biological tissues. Recent developments of multifunctional OCT (MF-OCT) provides multiple optical contrasts which can reveal currently unknown tissue properties. In this contribution we demonstrate multifunctional OCT specially designed for dermatological investigation. And by utilizing it to measure four different body parts of in vivo human skin, three-dimensional scattering OCT, OCT angiography, polarization uniformity tomography, and local birefringence tomography images were obtained by a single scan. They respectively contrast the structure and morphology, vasculature, melanin content and collagen traits of the tissue.

  3. Pressure sensitive multifunctional solar cells using carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Somani, Prakash R.

    2010-04-01

    A unique multifunctional device combining the photovoltaic action and pressure sensitivity is demonstrated which is based on the heterojunction of n-Si and carbon nanotubes (double walled carbon nanotubes or multiwalled carbon nanotubes) and using copper phthalocyanine surface modified indium-tin-oxide electrode and shows pressure dependent photovoltaic action. The device can work as a solar cell, pressure sensor, or photovoltaic pressure sensor. Such multifunctional organic/organic-inorganic hybrid solar cells are expected to find many applications in the near future.

  4. Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery.

    PubMed

    Yen, Swee Kuan; Padmanabhan, Parasuraman; Selvan, Subramanian Tamil

    2013-01-01

    In recent years, multifunctional nanoparticles (NPs) consisting of either metal (e.g. Au), or magnetic NP (e.g. iron oxide) with other fluorescent components such as quantum dots (QDs) or organic dyes have been emerging as versatile candidate systems for cancer diagnosis, therapy, and macromolecule delivery such as micro ribonucleic acid (microRNA). This review intends to highlight the recent advances in the synthesis and application of multifunctional NPs (mainly iron oxide) in theranostics, an area used to combine therapeutics and diagnostics. The recent applications of NPs in miRNA delivery are also reviewed. PMID:24396508

  5. Multifunctional Iron Oxide Nanoparticles for Diagnostics, Therapy and Macromolecule Delivery

    PubMed Central

    Yen, Swee Kuan; Padmanabhan, Parasuraman; Selvan, Subramanian Tamil

    2013-01-01

    In recent years, multifunctional nanoparticles (NPs) consisting of either metal (e.g. Au), or magnetic NP (e.g. iron oxide) with other fluorescent components such as quantum dots (QDs) or organic dyes have been emerging as versatile candidate systems for cancer diagnosis, therapy, and macromolecule delivery such as micro ribonucleic acid (microRNA). This review intends to highlight the recent advances in the synthesis and application of multifunctional NPs (mainly iron oxide) in theranostics, an area used to combine therapeutics and diagnostics. The recent applications of NPs in miRNA delivery are also reviewed. PMID:24396508

  6. [Multifunctional Nursing Beds Based on Intelligent Detection and Recovery].

    PubMed

    Jiang, Jiehuil; Pan, Xiaojie; Jiang, Xianbo; Yan, Zhuangzhi

    2016-01-01

    With the advent of the aging society, there will be a wide range of applications if novel intelligent multifunctional nursing beds can be developed for hospitals, bead houses and families at the same time. By listing and analyzing existing products, this paper summarized four function categories for multifunctional nursing beds, including security assurance, treatment aid, comfortability optimization, and human-machine interaction and communication. Finally, by comparing existing functions and potential user requirements, this paper proposed four function development trends, including physiological parameter monitoring, sleep aid, intelligent temperature control, and video communication. PMID:27197499

  7. Residential solar home resale analysis

    SciTech Connect

    Noll, S.A.

    1980-01-01

    One of the determinants of the market acceptance of solar technologies in the residential housing sector is the value placed upon the solar property at the time of resale. The resale factor is shown to be an important economic parameter when net benefits of the solar design are considered over a typical ownership cycle rather than the life cycle of the system. Although a study of solar resale in Davis, Ca, indicates that those particular homes have been appreciating in value faster than nonsolar market comparables, no study has been made that would confirm this conclusion for markets in other geograhical locations with supporting tests of statistical significance. The data to undertake such an analysis is available through numerous local sources; however, case by case data collection is prohibitively expensive. A recommended alternative approach is to make use of real estate market data firms who compile large data bases and provide multi-variate statistical analysis packages.

  8. Integrated residential photovoltaic array development

    NASA Technical Reports Server (NTRS)

    Shepard, N. F., Jr.

    1981-01-01

    Three basic module design concepts were analyzed with respect to both production and installation costs. The results of this evaluation were used to synthesize a fourth design which incorporates the best features of these initial concepts to produce a module/array design approach which offers the promise of a substantial reduction in the installed cost of a residential array. A unique waterproofing and mounting scheme was used to reduce the cost of installing an integral array while still maintaining a high probability that the installed array will be watertight for the design lifetime of the system. This recommended concept will also permit the array to be mounted as a direct or stand-off installation with no changes to the module design.

  9. 12 CFR 541.23 - Residential real estate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Residential real estate. 541.23 Section 541.23... AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 541.23 Residential real estate. The terms residential real estate... home used in part for business); (c) Other real estate used for primarily residential purposes...

  10. 12 CFR 541.16 - Improved residential real estate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Improved residential real estate. 541.16... REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 541.16 Improved residential real estate. The term improved residential real estate means residential real estate containing offsite or other...

  11. 12 CFR 541.16 - Improved residential real estate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true Improved residential real estate. 541.16 Section... REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 541.16 Improved residential real estate. The term improved residential real estate means residential real estate containing offsite or other...

  12. 12 CFR 141.23 - Residential real estate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Residential real estate. 141.23 Section 141.23... AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 141.23 Residential real estate. The terms residential real estate... home used in part for business); (c) Other real estate used for primarily residential purposes...

  13. 12 CFR 541.16 - Improved residential real estate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true Improved residential real estate. 541.16 Section... REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 541.16 Improved residential real estate. The term improved residential real estate means residential real estate containing offsite or other...

  14. 12 CFR 141.23 - Residential real estate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Residential real estate. 141.23 Section 141.23... AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 141.23 Residential real estate. The terms residential real estate... home used in part for business); (c) Other real estate used for primarily residential purposes...

  15. 12 CFR 141.23 - Residential real estate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Residential real estate. 141.23 Section 141.23... AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 141.23 Residential real estate. The terms residential real estate... home used in part for business); (c) Other real estate used for primarily residential purposes...

  16. 12 CFR 141.16 - Improved residential real estate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Improved residential real estate. 141.16... REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 141.16 Improved residential real estate. The term improved residential real estate means residential real estate containing offsite or other...

  17. 12 CFR 141.16 - Improved residential real estate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Improved residential real estate. 141.16... REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 141.16 Improved residential real estate. The term improved residential real estate means residential real estate containing offsite or other...

  18. 12 CFR 141.16 - Improved residential real estate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Improved residential real estate. 141.16... REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 141.16 Improved residential real estate. The term improved residential real estate means residential real estate containing offsite or other...

  19. 12 CFR 541.23 - Residential real estate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Residential real estate. 541.23 Section 541.23... AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 541.23 Residential real estate. The terms residential real estate... home used in part for business); (c) Other real estate used for primarily residential purposes...

  20. 12 CFR 541.16 - Improved residential real estate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Improved residential real estate. 541.16... REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 541.16 Improved residential real estate. The term improved residential real estate means residential real estate containing offsite or other...

  1. Novel Fabrication Strategies for Multifunctional Hydrogel Particles

    NASA Astrophysics Data System (ADS)

    Lewis, Chrisitna L.

    2011-12-01

    Three fabrication strategies for poly (ethylene glycol) (PEG) -based microparticles and their utility for exploiting the advantages of viral nanotemplates and DNA oligonucleotides are presented in this dissertation: 1. Nucleic Acid Hybridization Assembly of Viral Nanotemplates on Microparticles A flow lithography technique known as stop-flow lithography (SFL) was used to fabricate microparticles with discrete regions for sample identification and patterned assembly of functionalized tobacco mosaic virus (TMV) nanotemplates. TMV nanotemplates were programmed with linker DNA, complementary to the probe DNA in the assembly region of the microparticles. The hybridization-based assembly yielded specific, programmable, and spatially selective assembly of TMV nanotemplates on encoded hydrogel microparticles and demonstrates a novel high throughput route to create multiplexed and multifunctional viral-synthetic hybrid microentities. 2. Microparticles Containing Functionalized Viral Nanotemplates Functionalized viral assemblies were uniformly distributed throughout hydrogel microparticles by direct embedding with a microfluidic flow-focusing device and UV photopolymerization. Fluorescence and confocal microscopy images showed uniform distribution of the TMV nanotemplates. Microparticles containing TMV-templated palladium (Pd) nanoparticles exhibited catalytic activity for the dichromate reduction reaction. The results reveal that microparticles provide a stable and simple-to-handle carrier for TMV nanotemplates and address a critical challenge of 3D assembly of functionalized viral hybrid nanomaterials. 3. DNA-Conjugated Microparticles via Replica Molding (RM) DNA-conjugated microparticles were fabricated using a soft-lithographic batch processing-based technique, known as RM. A humidity controlled environment was found to minimize the negative effects of rapid evaporation and ensure uniformity across batch fabricated microparticles. It was also found that PEG

  2. Multi-functional Textiles for Military Applications

    NASA Astrophysics Data System (ADS)

    Malshe, Priyadarshini

    helped create a multi-functional fabric with an anti-bacterial bulk, hydrophilic back surface and repellent front surface for enhanced protective and aesthetic values.

  3. Development of a Residential Ground-Source Integrated Heat Pump

    SciTech Connect

    Rice, C Keith; Baxter, Van D; Hern, Shawn; McDowell, Tim; Munk, Jeffrey D; Shen, Bo

    2013-01-01

    A residential-size ground-source integrated heat pump (GSIHP) system has been developed and is currently being field tested. The system is a nominal 2-ton (7 kW) cooling capacity, variable-speed unit, which is multi-functional, e.g. space cooling, space heating, dedicated water heating, and simultaneous space cooling and water heating. High-efficiency brushless permanent-magnet (BPM) motors are used for the compressor, indoor blower, and pumps to obtain the highest component performance and system control flexibility. Laboratory test data were used to calibrate a vapor-compression simulation model (HPDM) for each of the four primary modes of operation. The model was used to optimize the internal control options and to simulate the selected internal control strategies, such as controlling to a constant air supply temperature in the space heating mode and a fixed water temperature rise in water heating modes. Equipment performance maps were generated for each operation mode as functions of all independent variables for use in TRNSYS annual energy simulations. These were performed for the GSIHP installed in a well-insulated 2600 ft2(242 m2) house and connected to a vertical ground loop heat exchanger(GLHE). We selected a 13 SEER (3.8 CSPF )/7.7 HSPF (2.3 HSPF, W/W) ASHP unit with 0.90 Energy Factor (EF) resistance water heater as the baseline for energy savings comparisons. The annual energy simulations were conducted over five US climate zones. In addition, appropriate ground loop sizes were determined for each location to meet 10-year minimum and maximum design entering water temperatures (EWTs) to the equipment. The prototype GSIHP system was predicted to use 52 to 59% less energy than the baseline system while meeting total annual space conditioning and water heating loads.

  4. Final materials, processes, and testing progress report for residential and non-residential applications

    NASA Astrophysics Data System (ADS)

    Forman, S. E.; Themelis, M. P.

    1982-06-01

    I-V curves were generated for the prototype residential photovoltaic modules at both the Northeast Residential Experiment Station (NE RES) and the Southwest Residential Experiment Station (SW RES). Analyses of these measurements are given. Also presented are site measurements at Mead, Nebraska, and at Bryan, Ohio. Visual and electrical failure analysis results are also given for photovoltaic modules at Mead, Nebraska, at Bryan, Ohio, and at the Natural Bridges National Monument.

  5. Personal, Portable, Multifunction-Devices and School Libraries

    ERIC Educational Resources Information Center

    Weaver, Anne

    2010-01-01

    To maximise learning value from one-to-one programs in schools, computing devices need to be personal, portable and multifunctional. It is likely that shared devices will not be as effective. The increased access provided by one-to-one devices creates great opportunities for school librarians to support their school technology directions and to…

  6. Multifunctional, Highly Flexible, Free-Standing 3D Polypyrrole Foam.

    PubMed

    Wang, Chunhui; Ding, Yujie; Yuan, Ye; Cao, Anyuan; He, Xiaodong; Peng, Qingyu; Li, Yibin

    2016-08-01

    Multifunctional, highly flexible 3D polypyrrole (PPy) foam is fabricated via a simple electrodeposition method by using nickel foam as the template. The 3D PPy foam has a unique interior structure and is robust enough to manipulate directly. PMID:27357260

  7. Multifunctional Charge-Transfer Single Crystals through Supramolecular Assembly.

    PubMed

    Xu, Beibei; Luo, Zhipu; Wilson, Andrew J; Chen, Ke; Gao, Wenxiu; Yuan, Guoliang; Chopra, Harsh Deep; Chen, Xing; Willets, Katherine A; Dauter, Zbigniew; Ren, Shenqiang

    2016-07-01

    Centimeter-sized segregated stacking TTF-C60 single crystals are crystallized by a mass-transport approach combined with solvent-vapor evaporation for the first time. The intermolecular charge-transfer interaction in the long-range ordered superstructure enables the crystals to demonstrate external stimuli-controlled multifunctionalities and angle/electrical-potential-dependent luminescence. PMID:27146726

  8. Multifunctional proteins revealed by overlapping clustering in protein interaction network

    PubMed Central

    Chapple, Charles E.; Guénoche, Alain; Brun, Christine

    2012-01-01

    Motivation: Multifunctional proteins perform several functions. They are expected to interact specifically with distinct sets of partners, simultaneously or not, depending on the function performed. Current graph clustering methods usually allow a protein to belong to only one cluster, therefore impeding a realistic assignment of multifunctional proteins to clusters. Results: Here, we present Overlapping Cluster Generator (OCG), a novel clustering method which decomposes a network into overlapping clusters and which is, therefore, capable of correct assignment of multifunctional proteins. The principle of OCG is to cover the graph with initial overlapping classes that are iteratively fused into a hierarchy according to an extension of Newman's modularity function. By applying OCG to a human protein–protein interaction network, we show that multifunctional proteins are revealed at the intersection of clusters and demonstrate that the method outperforms other existing methods on simulated graphs and PPI networks. Availability: This software can be downloaded from http://tagc.univ-mrs.fr/welcome/spip.php?rubrique197 Contact: brun@tagc.univ-mrs.fr Supplementary information: Supplementary data are available at Bioinformatics online. PMID:22080466

  9. The Impact of Multifunctional Genes on "Guilt by Association" Analysis

    PubMed Central

    Gillis, Jesse; Pavlidis, Paul

    2011-01-01

    Many previous studies have shown that by using variants of “guilt-by-association”, gene function predictions can be made with very high statistical confidence. In these studies, it is assumed that the “associations” in the data (e.g., protein interaction partners) of a gene are necessary in establishing “guilt”. In this paper we show that multifunctionality, rather than association, is a primary driver of gene function prediction. We first show that knowledge of the degree of multifunctionality alone can produce astonishingly strong performance when used as a predictor of gene function. We then demonstrate how multifunctionality is encoded in gene interaction data (such as protein interactions and coexpression networks) and how this can feed forward into gene function prediction algorithms. We find that high-quality gene function predictions can be made using data that possesses no information on which gene interacts with which. By examining a wide range of networks from mouse, human and yeast, as well as multiple prediction methods and evaluation metrics, we provide evidence that this problem is pervasive and does not reflect the failings of any particular algorithm or data type. We propose computational controls that can be used to provide more meaningful control when estimating gene function prediction performance. We suggest that this source of bias due to multifunctionality is important to control for, with widespread implications for the interpretation of genomics studies. PMID:21364756

  10. Photoinitiated cationic polymerization with multifunctional vinyl ether monomers

    SciTech Connect

    Cribello, J.V.; Lee, J.L.; Conlon, D.A.

    1983-01-01

    Until recently, multifunctional vinyl ether monomers have not been employed in UV curing applications. The recent discovery of diaryliodonium and triarylsulfonium salts as new classes of photoinitiators for cationic polylmerization has made it possible to formulate highly photosensitive UV curable coatings based on these monomers. The syntheses of these monomers and their reactivity as a function of their structure is reviewed and evaluated.

  11. Surface Intensive Materials Processing for Multi-Functional Purposes

    SciTech Connect

    Ila, D.; Williams, E.K.; Muntele, C.I.; George, M.A.; Poker, D.B.; Hensley, D.K.; Larkin, D.J.

    2000-03-06

    We have chosen silicon carbide (SiC) as a multi-functional material to demonstrate the application of surface intensive processing for device fabrication. We will highlight two devices which are produced in house at the Center for Irradiation of materials of Alabama A and M university: (A) High temperature electronic gas sensor, (B) High temperature optical properties/sensor.

  12. High-strength porous carbon and its multifunctional applications

    SciTech Connect

    Wojtowicz, Marek A; Rubenstein, Eric P; Serio, Michael A; Cosgrove, Joseph E

    2013-12-31

    High-strength porous carbon and a method of its manufacture are described for multifunctional applications, such as ballistic protection, structural components, ultracapacitor electrodes, gas storage, and radiation shielding. The carbon is produced from a polymer precursor via carbonization, and optionally by surface activation and post-treatment.

  13. Cyanate ester based multifunctional nanocomposites for structural capacitors

    NASA Astrophysics Data System (ADS)

    Sun, Weixing

    Two multifunctional cyanate ester based composites with nanofillers of core-shell microstructures were synthesized and investigated for dielectric, mechanical, and other particular properties for the application of multifunctional structural capacitors. The weight reduction and device integration in spacecraft can contribute to significant energy saving by employing multifunctional structural capacitors. Si nanoparticles/Bisphenol E cyanater ester (Si/BECy) nanocomposites show a significant increase in dielectric constant compared to neat BECy. A low dielectric loss tangent is still maintained in this system thanks to the core-shell (Si-SiO2) microstructure of Si particles. Incorporation of Si nanoparticles also results in a large increase in composite's storage modulus. Furthermore, the AC conductivity of the composite was observed to decrease under compressive mechanical stresses due to the piezoresistive effect of Si. Agglomerates of Fe3O4 nanoparticles coated with SiO2 are synthesized and incorporated into BECy to obtain nanocomposites, revealing an enhanced dielectric constant and storage modulus, and a relatively low loss tangent over a wide frequency and temperature range similar to Si/BECy system. Therefore, these novel cyanate ester based nanocomposites simultaneously display mechanical load-carrying, electric energy-storing and other functional properties, promising for multifunctional devices, in this case, structural capacitors.

  14. Photovoltaic Residential Applications Program Implementation Workshop Proceedings

    NASA Technical Reports Server (NTRS)

    Barbieri, R. H.

    1980-01-01

    Two major aspects of the workshop are presented: (1) presentations on the Photovoltaic program and the National Solar Heating and Cooling Demonstration program, and (2) discussions on the issues pertinent to the Residential Application program.

  15. Development of Residential SOFC Cogeneration System

    NASA Astrophysics Data System (ADS)

    Ono, Takashi; Miyachi, Itaru; Suzuki, Minoru; Higaki, Katsuki

    2011-06-01

    Since 2001 Kyocera has been developing 1kW class Solid Oxide Fuel Cell (SOFC) for power generation system. We have developed a cell, stack, module and system. Since 2004, Kyocera and Osaka Gas Co., Ltd. have been developed SOFC residential co-generation system. From 2007, we took part in the "Demonstrative Research on Solid Oxide Fuel Cells" Project conducted by New Energy Foundation (NEF). Total 57 units of 0.7kW class SOFC cogeneration systems had been installed at residential houses. In spite of residential small power demand, the actual electric efficiency was about 40%(netAC,LHV), and high CO2 reduction performance was achieved by these systems. Hereafter, new joint development, Osaka Gas, Toyota Motors, Kyocera and Aisin Seiki, aims early commercialization of residential SOFC CHP system.

  16. Converting Residential Drawing Courses to Metric.

    ERIC Educational Resources Information Center

    Goetsch, David L.

    1980-01-01

    Describes the process of metric conversion in residential drafting courses. Areas of concern are metric paper sizes; metric scale; plot, foundation, floor and electric plans; wall sections; elevations; and heat loss/ heat gain calculations. (SK)

  17. 24 CFR 203.672 - Residential areas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... used by persons active in the real estate industry in the affected area. (b) HUD shall establish such... constitutes a local economic market for the purchase and sale of residential real estate. In...

  18. RESIDENTIAL RADON RESISTANT CONSTRUCTION FEATURE SELECTION SYSTEM

    EPA Science Inventory

    The report describes a proposed residential radon resistant construction feature selection system. The features consist of engineered barriers to reduce radon entry and accumulation indoors. The proposed Florida standards require radon resistant features in proportion to regional...

  19. Chamberless residential warm air furnace design

    SciTech Connect

    Godfree, J.

    1996-07-01

    This brief paper is an introduction to the concept of designing residential warm air furnaces without combustion chambers. This is possible since some small burners do not require the thermal support of a combustion chamber to complete the combustion process.

  20. Technician Losses in Public Residential Facilities.

    ERIC Educational Resources Information Center

    Zaharia, E. S.; Baumeister, A. A.

    1979-01-01

    A cross-organizational longitudinal survey was undertaken of 12 state-operated residential facilities for the mentally retarded to gauge the extent to which technician-level work forces are affected by turnover and absenteeism. (Author/CL)

  1. RACIAL RESIDENTIAL SEGREGATION AND ADVERSE BIRTH OUTCOMES

    EPA Science Inventory

    INTRODUCTION. The disparity between black and white women's adverse birth outcomes has been subject to much investigation, yet the factors underlying its persistence remain elusive, which has encouraged research on neighborhood-level influences, including racial residential segr...

  2. Residential Segregation in Southern Cities: 1970

    ERIC Educational Resources Information Center

    And Others; Roof, Wade Clark

    1976-01-01

    Based on an analysis of the age, size, percent black, and occupational income differential in 32 southern cities, the findings show that age is still the strongest predictor of residential segregation. (Author)

  3. Saying Good-bye in Residential Treatment.

    ERIC Educational Resources Information Center

    Bale, Tom

    1979-01-01

    Presents the case history of a 13-year-old asthmatic boy in residential treatment in order to illustrate how experiences in the milieu can become a vehicle for a child to gain better control over separation anxiety. (CM)

  4. Residential market transformation: National and regional indicators

    SciTech Connect

    Van Wie McGrory, Laura L.; McNamara, Maureen; Suozzo, Margaret

    2000-06-01

    A variety of programs are underway to address market barriers to the adoption of energy-efficient residential technologies and practices. Most are administered by utilities, states, or regions that rely on the Energy Star as a consistent platform for program marketing and messaging. This paper reviews regional and national market transformation activities for three key residential end-uses -- air conditioning, clothes washing, and lighting -- characterizing current and ongoing programs; reporting on progress; identifying market indicators; and discussing implications.

  5. Utility integration issues of residential photovoltaic systems

    NASA Astrophysics Data System (ADS)

    Yamayee, Z. A.; Peschon, J.

    1981-05-01

    The economic aspects of residential solar photovoltaic (SPV) systems are discussed from the electric utility perspective. The following schemes of SPV integration are considered: (1) SPV with complete utility buy-back and backup; (2) SPV with utility system storage; and (3) SPV with residential storage. Estimates are made of the price that the utility might pay for SPV owner's surplus energy compared to what it would charge for deficits by evaluating economic savings of SVP to the utility.

  6. Residential photovoltaic system simulation: Thermal aspects

    NASA Astrophysics Data System (ADS)

    Hart, G. W.; Raghuraman, P.

    1982-04-01

    A TRNSYS simulation was developed to simulate the performance of utility interactive residential photovoltaic energy systems. The PV system is divided into its major functional components, which are individually described with computer models. These models are described in detail. The results of simulation and actual measured data obtained a MIT Lincoln Laboratory's Northeast Residential Station are compared. The thermal influences on the design of such photovoltaic energy systems are given particular attention.

  7. Voluntary initiation of movement: multifunctional integration of subjective agency

    PubMed Central

    Grüneberg, Patrick; Kadone, Hideki; Suzuki, Kenji

    2015-01-01

    This paper investigates subjective agency (SA) as a special type of efficacious action consciousness. Our central claims are, firstly, that SA is a conscious act of voluntarily initiating bodily motion. Secondly, we argue that SA is a case of multifunctional integration of behavioral functions being analogous to multisensory integration of sensory modalities. This is based on new perspectives on the initiation of action opened up by recent advancements in robot assisted neuro-rehabilitation which depends on the active participation of the patient and yields experimental evidence that there is SA in terms of a conscious act of voluntarily initiating bodily motion (phenomenal performance). Conventionally, action consciousness has been considered as a sense of agency (SoA). According to this view, the conscious subject merely echoes motor performance and does not cause bodily motion. Depending on sensory input, SoA is implemented by means of unifunctional integration (binding) and inevitably results in non-efficacious action consciousness. In contrast, SA comes as a phenomenal performance which causes motion and builds on multifunctional integration. Therefore, the common conception of the brain should be shifted toward multifunctional integration in order to allow for efficacious action consciousness. For this purpose, we suggest the heterarchic principle of asymmetric reciprocity and neural operators underlying SA. The general idea is that multifunctional integration allows conscious acts to be simultaneously implemented with motor behavior so that the resulting behavior (SA) comes as efficacious action consciousness. Regarding the neural implementation, multifunctional integration rather relies on operators than on modular functions. A robotic case study and possible experimental setups with testable hypotheses building on SA are presented. PMID:26052308

  8. Voluntary initiation of movement: multifunctional integration of subjective agency.

    PubMed

    Grüneberg, Patrick; Kadone, Hideki; Suzuki, Kenji

    2015-01-01

    This paper investigates subjective agency (SA) as a special type of efficacious action consciousness. Our central claims are, firstly, that SA is a conscious act of voluntarily initiating bodily motion. Secondly, we argue that SA is a case of multifunctional integration of behavioral functions being analogous to multisensory integration of sensory modalities. This is based on new perspectives on the initiation of action opened up by recent advancements in robot assisted neuro-rehabilitation which depends on the active participation of the patient and yields experimental evidence that there is SA in terms of a conscious act of voluntarily initiating bodily motion (phenomenal performance). Conventionally, action consciousness has been considered as a sense of agency (SoA). According to this view, the conscious subject merely echoes motor performance and does not cause bodily motion. Depending on sensory input, SoA is implemented by means of unifunctional integration (binding) and inevitably results in non-efficacious action consciousness. In contrast, SA comes as a phenomenal performance which causes motion and builds on multifunctional integration. Therefore, the common conception of the brain should be shifted toward multifunctional integration in order to allow for efficacious action consciousness. For this purpose, we suggest the heterarchic principle of asymmetric reciprocity and neural operators underlying SA. The general idea is that multifunctional integration allows conscious acts to be simultaneously implemented with motor behavior so that the resulting behavior (SA) comes as efficacious action consciousness. Regarding the neural implementation, multifunctional integration rather relies on operators than on modular functions. A robotic case study and possible experimental setups with testable hypotheses building on SA are presented. PMID:26052308

  9. Integrated residential photovoltaic array development

    NASA Technical Reports Server (NTRS)

    Royal, G. C., III

    1981-01-01

    Sixteen conceptual designs of residential photovoltaic arrays are described. Each design concept was evaluated by an industry advisory panel using a comprehensive set of technical, economic and institutional criteria. Key electrical and mechanical concerns that effect further array subsystem development are also discussed. Three integrated array design concepts were selected by the advisory panel for further optimization and development. From these concepts a single one will be selected for detailed analysis and prototype fabrication. The three concepts selected are: (1) An array of frameless panels/modules sealed in a T shaped zipper locking neoprene gasket grid pressure fitted into an extruded aluminum channel grid fastened across the rafters. (2) An array of frameless modules pressure fitted in a series of zipper locking EPDM rubber extrusions adhesively bonded to the roof. Series string voltage is developed using a set of integral tongue connectors and positioning blocks. (3) An array of frameless modules sealed by a silicone adhesive in a prefabricated grid of rigid tape and sheet metal attached to the roof.

  10. The 1986 residential occupant survey

    SciTech Connect

    Ivey, D.L.; Alley, P.K.

    1987-04-01

    In 1986, Pacific Northwest Laboratory developed the Residential Occupant Survey-Spring '86, which was implemented. The overall purpose of the study was to collect demographic, attitudinal, and behavioral data related to the use and conservation of electricity in dwellings participating in the Bonneville Power Administration's End-Use Load and Conservation Assessment Program (ELCAP). Information was collected on the respondents' perceptions of the energy efficiency of their dwelling, temperature the dwelling was kept when people were at home and awake during the last heating season, which rooms, if any, were not heated during the last heating season, number of times the dwelling was unoccupied for at least one week, number of times pets were let out of the dwelling per day, attitudes toward energy use and conservation and several socio-demographic variables such as age, sex, and total household income. The results of the data analyses showed age to be an important factor for reported indoor temperature and perceived energy efficiency of the dwelling. The results also showed that almost 60% of the ELCAP occupants do not heat one or more rooms during the heating season, and almost 45% of the ELCAP dwellings were unoccupied for at least one week during the reporting period. In terms of the reported allocation of household income for household energy expenses, the results showed that the reported dollar amount spent for the expenses remained relatively constant over income levels.

  11. Short-Stay Residential Experience: Residential Work by Secondary School Pupils.

    ERIC Educational Resources Information Center

    Schools Council, London (England).

    Most secondary schools in Great Britain today have implemented residential courses. They have built, bought, or adapted premises ranging from derelict colleges to country houses for use as residential centers where students may spend from a few days to several weeks studying, working, or learning to use leisure time. This publication examines…

  12. Residential Programming for Mentally Retarded Persons. Volume III, Developmental Programming in the Residential Facility.

    ERIC Educational Resources Information Center

    National Association for Retarded Children, Arlington, TX. South Central Regional Office.

    The third of four booklets on residential programing for the mentally retarded is intended to help parents evaluate residential services and participate in decisions about program design and implementation. Areas of appropriate program emphasis are indicated for different age groups and for the various degrees of mental retardation from profound…

  13. Differences between Residential and Non-Residential Fathers on Sexual Socialisation of African American Youth

    ERIC Educational Resources Information Center

    Sneed, Carl D.; Willis, Leigh A.

    2016-01-01

    This study investigated differences between residential and non-residential fathers on topics discussed during father-child sex communication and factors associated with child sexual socialisation. Young people (N = 159, 53% female) provided self-reports using computer surveys on the role of their fathers on father-child sex communication, general…

  14. Redefining Residential: Family-Driven Care in Residential Treatment--Family Members Speak

    ERIC Educational Resources Information Center

    Residential Treatment for Children & Youth, 2009

    2009-01-01

    This is the sixth in a series of papers issued by the American Association of Children's Residential Centers (AACRC) regarding emerging and best practices in the field of residential treatment for children, youth, and families. AACRC is a long standing national association focused exclusively on practice and policy issues related to the provision…

  15. Functional and Multifunctional Polymers: Materials for Smart Structures

    NASA Technical Reports Server (NTRS)

    Arnold, S.; Pratt, L. M.; Li, J.; Wuagaman, M.; Khan, I. M.

    1996-01-01

    The ultimate goal of the research in smart structures and smart materials is the development of a new generation of products/devices which will perform better than products/devices built from passive materials. There are a few examples of multilayer polymer systems which function as smart structures, e.g. a synthetic muscle which is a multilayer assembly of a poly(ethylene) layer, a gold layer, and a poly(pyrrole) layer immersed in a liquid electrolyte. Oxidation and reductions of the active pyrrole layer causes the assembly to reversibly deflect and mimic biological muscles. The drawback of such a setup is slow response times and the use of a liquid electrolyte. We have developed multifunctional polymers which will eliminate the use of a liquid electrolyte, and also because the functionalities of the polymers are within a few hundred angstroms, an improved response time to changes in the external field should be possible. Such multifunctional polymers may be classified as the futuristic 'smart materials.' These materials are composed of a number of different functionalities which work in a synergistic fashion to function as a device. The device performs on the application of an external field and such multifunctional polymers may be scientifically labeled as 'field responsive polymers.' Our group has undertaken a systematic approach to develop functional and multifunctional polymers capable of functioning as field responsive polymers. Our approach utilizes multicomponent polymer systems (block copolymers and graft copolymers), the strategy involves the preparation of block or graft copolymers where the functionalities are limited to different phases in a microphase separated system. Depending on the weight (or volume) fractions of each of the components, different microstructures are possible. And, because of the intimate contact between the functional components, an increase in the synergism between the functionalities may be observed. In this presentation, three

  16. Post-Retrofit Residential Assessments

    SciTech Connect

    Lancaster, Ross; lutzenhiser, Loren; Moezzi, Mithra; Widder, Sarah H.; Chandra, Subrato; Baechler, Michael C.

    2012-04-30

    This study examined a range of factors influencing energy consumption in households that had participated in residential energy-efficiency upgrades. The study was funded by a grant from the U.S. Department of Energy’s Pacific Northwest National Laboratory and was conducted by faculty and staff of Portland State University Center for Urban Studies and Department of Economics. This work was made possible through the assistance and support of the Energy Trust of Oregon (ETO), whose residential energy-efficiency programs provided the population from which the sample cases were drawn. All households in the study had participated in the ETO Home Performance with Energy Star (HPwES) program. A number of these had concurrently pursued measures through other ETO programs. Post-retrofit energy outcomes are rarely investigated on a house-by-house basis. Rather, aggregate changes are ordinarily the focus of program impact evaluations, with deviation from aggregate expectations chalked up to measurement error, the vagaries of weather and idiosyncrasies of occupants. However, understanding how homes perform post-retrofit on an individual basis can give important insights to increase energy savings at the participant and the programmatic level. Taking a more disaggregated approach, this study analyzed energy consumption data from before and after the retrofit activity and made comparisons with engineering estimates for the upgrades, to identify households that performed differently from what may have been expected based on the estimates. A statistical analysis using hierarchal linear models, which accounted for weather variations, was performed looking separately at gas and electrical use during the periods before and after upgrades took place. A more straightforward comparison of billing data for 12-month periods before and after the intervention was also performed, yielding the majority of the cases examined. The later approach allowed total energy use and costs to be

  17. Multifunctional nanoarchitectures from DNA-based ABC monomers

    NASA Astrophysics Data System (ADS)

    Lee, Jong B.; Roh, Young H.; Um, Soong Ho; Funabashi, Hisakage; Cheng, Wenlong; Cha, Judy J.; Kiatwuthinon, Pichamon; Muller, David A.; Luo, Dan

    2009-07-01

    The ability to attach different functional moieties to a molecular building block could lead to applications in nanoelectronics, nanophotonics, intelligent sensing and drug delivery. The building unit needs to be both multivalent and anisotropic, and although many anisotropic building blocks have been created, these have not been universally applicable. Recently, DNA has been used to generate various nanostructures or hybrid systems, and as a generic building block for various applications. Here, we report the creation of anisotropic, branched and crosslinkable building blocks (ABC monomers) from which multifunctional nanoarchitectures have been assembled. In particular, we demonstrate a target-driven polymerization process in which polymers are generated only in the presence of a specific DNA molecule, leading to highly sensitive pathogen detection. Using this monomer system, we have also designed a biocompatible nanovector that delivers both drugs and tracers simultaneously. Our approach provides a general yet versatile route towards the creation of a range of multifunctional nanoarchitectures.

  18. Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

    PubMed Central

    Torchilin, Vladimir P.

    2015-01-01

    The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the in vivo effectiveness of drugs is now well established. The development of multifunctional and stimulus-sensitive NDDSs is an active area of current research. Such NDDSs can have long circulation times, target the site of the disease and enhance the intracellular delivery of a drug. This type of NDDS can also respond to local stimuli that are characteristic of the pathological site by, for example, releasing an entrapped drug or shedding a protective coating, thus facilitating the interaction between drug-loaded nanocarriers and target cells or tissues. In addition, imaging contrast moieties can be attached to these carriers to track their real-time biodistribution and accumulation in target cells or tissues. Here, I highlight recent developments with multifunctional and stimuli-sensitive NDDSs and their therapeutic potential for diseases including cancer, cardiovascular diseases and infectious diseases. PMID:25287120

  19. Recent Trends in Multifunctional Liposomal Nanocarriers for Enhanced Tumor Targeting

    PubMed Central

    Perche, Federico; Torchilin, Vladimir P.

    2013-01-01

    Liposomes are delivery systems that have been used to formulate a vast variety of therapeutic and imaging agents for the past several decades. They have significant advantages over their free forms in terms of pharmacokinetics, sensitivity for cancer diagnosis and therapeutic efficacy. The multifactorial nature of cancer and the complex physiology of the tumor microenvironment require the development of multifunctional nanocarriers. Multifunctional liposomal nanocarriers should combine long blood circulation to improve pharmacokinetics of the loaded agent and selective distribution to the tumor lesion relative to healthy tissues, remote-controlled or tumor stimuli-sensitive extravasation from blood at the tumor's vicinity, internalization motifs to move from tumor bounds and/or tumor intercellular space to the cytoplasm of cancer cells for effective tumor cell killing. This review will focus on current strategies used for cancer detection and therapy using liposomes with special attention to combination therapies. PMID:23533772

  20. MIC polar discriminators and multifunction modules in EW systems

    NASA Astrophysics Data System (ADS)

    Chelli, R.; Gasperini, S.; Quaglia, A.

    In the design of modern airborne and shipborne electronic warfare (EW) systems, problems arise with respect to weight, size, cost and repeatability demands. The approaches used to obtain solutions to those problems frequently involve the use of new structures, based on the development of integrated microwave subsystem and multifunction modules. The two most useful configurations are related to strip-line and microstrip designs. A Polar Frequency Discriminator (PFD) is a subsystem which relates its output angle with an input frequency. This subsystem includes a power splitter, a delay line, and a Polar Phase Discriminator (PPD) with four detectors. A PPD which includes three 3-dB hybrid couplers, and a power splitter is considered. Attention is given to the development of suitable PFDs, and the design of a mcirostrip broadband multifunction component. The component is used for a Built-In Test Equipment (BITE) in a ship-borne system.

  1. Multifunctional fluorescent and magnetic nanoparticles for biomedical applications

    NASA Astrophysics Data System (ADS)

    Selvan, Subramanian T.

    2012-03-01

    Hybrid multifunctional nanoparticles (NPs) are emerging as useful probes for magnetic based targeting, delivery, cell separation, magnetic resonance imaging (MRI), and fluorescence-based bio-labeling applications. Assessing from the literature, the development of multifunctional NPs for multimodality imaging is still in its infancy state. This report focuses on our recent work on quantum dots (QDs), magnetic NPs (MNPs) and bi-functional NPs (composed of either QDs or rare-earth NPs, and magnetic NPs - iron oxide or gadolinium oxide) for multimodality imaging based biomedical applications. The combination of MRI and fluorescence would ally each other in improving the sensitivity and resolution, resulting in improved and early diagnosis of the disease. The challenges in this area are discussed.

  2. Ultralight nanofibre-assembled cellular aerogels with superelasticity and multifunctionality

    NASA Astrophysics Data System (ADS)

    Si, Yang; Yu, Jianyong; Tang, Xiaomin; Ge, Jianlong; Ding, Bin

    2014-12-01

    Three-dimensional nanofibrous aerogels (NFAs) that are both highly compressible and resilient would have broad technological implications for areas ranging from electrical devices and bioengineering to damping materials; however, creating such NFAs has proven extremely challenging. Here we report a novel strategy to create fibrous, isotropically bonded elastic reconstructed (FIBER) NFAs with a hierarchical cellular structure and superelasticity by combining electrospun nanofibres and the fibrous freeze-shaping technique. Our approach causes the intrinsically lamellar deposited electrospun nanofibres to assemble into elastic bulk aerogels with tunable densities and desirable shapes on a large scale. The resulting FIBER NFAs exhibit densities of >0.12 mg cm-3, rapid recovery from deformation, efficient energy absorption and multifunctionality in terms of the combination of thermal insulation, sound absorption, emulsion separation and elasticity-responsive electric conduction. The successful synthesis of such fascinating materials may provide new insights into the design and development of multifunctional NFAs for various applications.

  3. Ultralight nanofibre-assembled cellular aerogels with superelasticity and multifunctionality.

    PubMed

    Si, Yang; Yu, Jianyong; Tang, Xiaomin; Ge, Jianlong; Ding, Bin

    2014-01-01

    Three-dimensional nanofibrous aerogels (NFAs) that are both highly compressible and resilient would have broad technological implications for areas ranging from electrical devices and bioengineering to damping materials; however, creating such NFAs has proven extremely challenging. Here we report a novel strategy to create fibrous, isotropically bonded elastic reconstructed (FIBER) NFAs with a hierarchical cellular structure and superelasticity by combining electrospun nanofibres and the fibrous freeze-shaping technique. Our approach causes the intrinsically lamellar deposited electrospun nanofibres to assemble into elastic bulk aerogels with tunable densities and desirable shapes on a large scale. The resulting FIBER NFAs exhibit densities of >0.12 mg cm(-3), rapid recovery from deformation, efficient energy absorption and multifunctionality in terms of the combination of thermal insulation, sound absorption, emulsion separation and elasticity-responsive electric conduction. The successful synthesis of such fascinating materials may provide new insights into the design and development of multifunctional NFAs for various applications. PMID:25512095

  4. Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display

    DOEpatents

    Glazer, Alexander N.; Cai, Yuping

    2003-11-18

    The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein, including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.

  5. Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display

    DOEpatents

    Glazer, Alexander N.; Cai, Yuping

    2007-02-13

    The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein. including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.

  6. Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display

    DOEpatents

    Glazer, Alexander N.; Cai, Yuping

    2007-01-30

    The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein, including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.

  7. Multifunctional Graphene/Platinum/Nafion Hybrids via Ice Templating

    SciTech Connect

    Estevez, Luis; Kelarakis, Antonios; Gong, Qianming; Da’as, Eman Husni; Giannelis, Emmanuel P.

    2011-04-27

    We report the synthesis of multifunctional hybrids in both films and bulk form, combining electrical and ionic conductivity with porosity and catalytic activity. The hybrids are synthesized by a two-step process: (a) ice templation of an aqueous suspension comprised of Nafion, graphite oxide, and chloroplatinic acid to form a microcellular porous network and (b) mild reduction in hydrazine or monosodium citrate which leads to graphene-supported Pt nanoparticles on a Nafion scaffold

  8. Multi-functional sensor system for molten salt technologies

    SciTech Connect

    Redey, Laszlo; Gourishankar, Karthick; Williamson, Mark A.

    2009-12-15

    The present invention relates to a multi-functional sensor system that simultaneously measures cathode and anode electrode potentials, dissolved ion (i.e. oxide) concentration, and temperatures in an electrochemical cell. One embodiment of the invented system generally comprises: a reference(saturated) electrode, a reference(sensing) electrode, and a data acquisition system. Thermocouples are built into the two reference electrodes to provide important temperature information.

  9. Multifunctional composites aircraft applications in Finmeccanica - Some examples

    NASA Astrophysics Data System (ADS)

    Iannone, Michele

    2016-05-01

    Some examples of multifunctional composite materials presently developed by Finmeccanica are described. The basic concept is to modify the material/structure by adding a further function to the structural basic one. The described examples refer to: improvement of processability; self-diagnostic capability; improvement of the allowables, acting on reduction of the knock down factor required to take in account the environmental ageing effects.

  10. Hierarchical manufacture and characterization of multifunctional nanocomposite structures

    NASA Astrophysics Data System (ADS)

    Veedu, Vinod P. V.

    The objective of this work is to develop multifunctional 3-D nanocomposite structures in an attempt to solve the shortcomings of the traditional composite materials. To achieve this goal, at first a detailed analysis of the properties of the basic nano reinforcement, carbon nanotube, was performed in terms of mechanical behavior, thermoelastic responses and thermal conductivity using an analytical technique, namely, asymptotic homogenization method. In our initial experimental works, different polymer resins were reinforced with nanotubes as well as nanoparticles and their mechanical performances were investigated. These experiments reveal that at higher weight percentage loading of the nanoparticles and nanotubes there are dominant issues such as alignment and dispersion, which would weaken the material. This led us to seek a novel approach to nanocomposites. In this report, two multifunctional nanocomposite structures are introduced: nanotube based brushes and hierarchical 3-D nanocomposite. The nanotube brushes were fabricated using chemical vapor deposition. Functions performed by these brushes such as mechanical and chemical cleaning, painting and electrical contacts will be discussed. Also, we unveil a novel approach to the 3-D composite challenge, without altering the existing 2-D stack design, based on the concept of interlaminar carbon nanotube forests that would provide enhanced multifunctional properties in the thickness direction. The nanotube coated fabric cloths serve as building blocks for the multi-layered 3-D composites with the nanotubes forests providing much needed interlaminar strength and toughness under various loading conditions. For the fabricated 3-D composites with nanotube forests, we demonstrate remarkable improvements in the interlaminar fracture toughness, delamination resistance, in-plane mechanical properties, damping, thermoelastic behavior, and thermal and electrical conductivities providing truly three-dimensional multifunctional

  11. Information processing with a single multifunctional nanofluidic diode

    NASA Astrophysics Data System (ADS)

    Ramirez, Patricio; Ali, Mubarak; Ensinger, Wolfgang; Mafe, Salvador

    2012-09-01

    We show that a multifunctional nanofluidic diode, based on a single pH-sensitive polymeric pore, can be used for different information processing tasks. This fact should permit a significant simplification of the logic circuitry in physico-chemical processors. The inputs are the pH values in the external solutions and the applied potential difference (voltage). The output is the electrical pore conductance. As a proof of concept, different logic and arithmetic computational functions are demonstrated.

  12. The sensitizing capacity of multifunctional acrylates in the guinea pig.

    PubMed

    Björkner, B

    1984-10-01

    The multifunctional acrylates used in ultraviolet (UV) curable resins act as cross-linkers and "diluents". They are usually based on di(meth)acrylate esters of dialcohols or tri- and tetra-acrylate esters of polyalcohols. In UV-curable coatings, the most commonly used are pentaerythritol triacrylate (PETA), trimethylolpropane triacrylate (TMPTA) and 1,6-hexanediol diacrylate (HDDA). In other uses, such as dental composite resin materials, the dimethacrylic monomers based on n-ethylene glycol are the most useful. The sensitizing capacity of various multifunctional acrylates and their cross-reactivity pattern have been investigated with the guinea pig maximization test. The tests show that BUDA (1,4-butanediol diacrylate) and HDDA are moderate to strong sensitizers and that they probably cross-react with each other. The n-ethylene glycol diacrylates and methacrylates tested are weak or non-sensitizers. Tripropylene glycol diacrylate (TPGDA) is a moderate and neopentyl glycol diacrylate (NPGDA) a strong sensitizer, whereas neopentyl glycol dimethacrylate is a non-sensitizer. The commercial PETA is a mixture of pentaerythritol tri- and tetra-acrylate (PETA-3 and PETA-4). PETA-3 is a much stronger sensitizer than PETA-4. Simultaneous reactions were seen between PETA-3, PETA-4 and TMPTA. The oligotriacrylate OTA 480 is a moderate sensitizer, but no concomitant reactions were seen with PETA-3, PETA-4 or TMPTA. Of the multifunctional acrylates tested, the di- and triacrylic compounds should be regarded as potent sensitizers. The methacrylated multifunctional acrylic compounds are weak or non-sensitizers. PMID:6499426

  13. Multifunctionality assessment of urban agriculture in Beijing City, China.

    PubMed

    Peng, Jian; Liu, Zhicong; Liu, Yanxu; Hu, Xiaoxu; Wang, An

    2015-12-15

    As an important approach to the realization of agricultural sustainable development, multifunctionality has become a hot spot in the field of urban agriculture. Taking 13 agricultural counties of Beijing City as the assessing units, this study selects 10 assessing index from ecological, economic and social aspects, determines the index weight using Analytic Hierarchy Process (AHP) method, and establishes an index system for the integrated agricultural function. Based on standardized data from agricultural census and remote sensing, the integrated function and multifunctionality of urban agriculture in Beijing City are assessed through the index grade mapping. The results show that agricultural counties with the highest score in ecological, economic, and social function are Yanqing, Changping, and Miyun, respectively; and the greatest disparity among those counties is economic function, followed by social and ecological function. Topography and human disturbance may be the factors that affect integrated agricultural function. The integrated agricultural function of Beijing rises at the beginning then drops later with the increase of mean slope, average altitude, and distance from the city. The whole city behaves balance among ecological, economic, and social functions at the macro level, with 8 out of the 13 counties belonging to ecology-society-economy balanced areas, while no county is dominant in only one of the three functions. On the micro scale, however, different counties have their own functional inclination: Miyun, Yanqing, Mentougou, and Fengtai are ecology-society dominant, and Tongzhou is ecology-economy dominant. The agricultural multifunctionality in Beijing City declines from the north to the south, with Pinggu having the most significant agricultural multifunctionality. The results match up well with the objective condition of Beijing's urban agriculture planning, which has proved the methodological rationality of the assessment to a certain extent

  14. Multifunctional optical system-on-a-chip for heterogeneous fiber optic sensor networks

    NASA Astrophysics Data System (ADS)

    Yu, Miao; Pang, Cheng; Gupta, Ashwani

    2015-08-01

    In this article, we review our recent progress on the development of a multifunctional optical system-on-a-chip platform, which can be used for achieving heterogeneous wireless fiber optical sensor networks. A multifunctional optical sensor platform based on the micro-electromechanical systems (MEMS) technology is developed. The key component of the multifunctional optical sensor platform is a MEMS based tunable Fabry-Pérot (FP) filter, which can be used as a phase modulator or a wavelength tuning device in a multifunctional optical sensing system. Mechanics model of the FP filter and optics model of the multifunctional optical sensing system are developed to facilitate the design of the filter. The MEMS FP filter is implemented in a multifunctional optical sensing system including both Fabry-Perot interferometer based sensors and Fiber Bragg grating sensors. The experimental results indicate that this large dynamic range tunable filter can enable high performance heterogeneous optical sensing for many applications.

  15. Multifunctional and specialized spinal interneurons for turtle limb movements.

    PubMed

    Berkowitz, Ari

    2010-06-01

    The turtle spinal cord can help reveal how vertebrate central nervous system (CNS) circuits select and generate an appropriate limb movement in each circumstance. Both multifunctional and specialized spinal interneurons contribute to the motor patterns for the three forms of scratching, forward swimming, and flexion reflex. Multifunctional interneurons, activated during all of these motor patterns, can have axon terminal arborizations in the ventral horn, where they likely contribute to limb motor output. Specialized interneurons can be specialized for a behavior, as opposed to a phase or motor synergy. Interneurons specialized for scratching can be hyperpolarized throughout swimming. Interneurons specialized for flexion reflex can be hyperpolarized throughout scratching and swimming. Some structure-function correlations have been revealed: flexion reflex-selective interneurons had somata exclusively in the dorsal horn, in contrast to scratch-activated interneurons. Transverse interneurons, defined by quantitative morphological criteria, had higher peak firing rates, narrower action potentials, briefer afterhyperpolarizations, and larger membrane potential oscillations than scratch-activated interneurons with different dendritic morphologies. Future investigations will focus on how multifunctional and specialized spinal interneurons interact to generate each motor output. PMID:20536926

  16. Direct Assembly of Hydrophobic Nanoparticles to Multifunctional Structures

    SciTech Connect

    Lu, Zhenda; Yin, Yadong; Chi, Miaofang

    2011-01-01

    We present a general process that allows convenient production of multifunctional composite particles by direct self-assembly of hydrophobic nanoparticles on host nanostructures containing high-density surface thiol groups. Hydrophobic nanoparticles of various compositions and combinations can be directly assembled onto the host surface through the strong coordination interactions between metal cations and thiol groups. The resulting structures can be further conveniently overcoated with a layer of normal silica to stabilize the assemblies and render them highly dispersible in water for biomedical applications. As the entire fabrication process does not involve complicated surface modification procedures, the hydrophobic ligands on the nanoparticles are not disturbed significantly so that they retain their original properties such as highly efficient luminescence. Many complex composite nanostructures with tailored functions can be efficiently produced by using this versatile approach. For example, multifunctional nonspherical nanostructures can be efficiently produced by using mercapto-silica coated nano-objects of arbitrary shapes as hosts for immobilizing functional nanoparticles. Multilayer structures can also be achieved by repeating the mercapto-silica coating and nanoparticle immobilization processes. Such assembly approach will provide the research community a highly versatile, configurable, scalable, and reproducible process for the preparation of various multifunctional structures.

  17. Effective Design of Multifunctional Peptides by Combining Compatible Functions

    PubMed Central

    Diener, Christian; Garza Ramos Martínez, Georgina; Moreno Blas, Daniel; Castillo González, David A.; Corzo, Gerardo; Castro-Obregon, Susana; Del Rio, Gabriel

    2016-01-01

    Multifunctionality is a common trait of many natural proteins and peptides, yet the rules to generate such multifunctionality remain unclear. We propose that the rules defining some protein/peptide functions are compatible. To explore this hypothesis, we trained a computational method to predict cell-penetrating peptides at the sequence level and learned that antimicrobial peptides and DNA-binding proteins are compatible with the rules of our predictor. Based on this finding, we expected that designing peptides for CPP activity may render AMP and DNA-binding activities. To test this prediction, we designed peptides that embedded two independent functional domains (nuclear localization and yeast pheromone activity), linked by optimizing their composition to fit the rules characterizing cell-penetrating peptides. These peptides presented effective cell penetration, DNA-binding, pheromone and antimicrobial activities, thus confirming the effectiveness of our computational approach to design multifunctional peptides with potential therapeutic uses. Our computational implementation is available at http://bis.ifc.unam.mx/en/software/dcf. PMID:27096600

  18. Distributed multifunctional sensor network for composite structural state sensing

    NASA Astrophysics Data System (ADS)

    Qing, Xinlin P.; Wang, Yishou; Gao, Limin; Kumar, Amrita

    2012-04-01

    Advanced fiber reinforced composite materials are becoming the main structural materials of next generation of aircraft because of their high strength and stiffness to weight ratios, and strong designability. In order to take full advantages of composite materials, there is a need to develop an embeddable multifunctional sensing system to allow a structure to "feel" and "think" its structural state. In this paper, the concept of multifunctional sensor network integrated with a structure, similar to the human nervous system, has been developed. Different types of network sensors are permanently integrated within a composite structure to sense structural strain, temperature, moisture, aerodynamic pressure; monitor external impact on the structure; and detect structural damages. Utilizing this revolutionary concept, future composite structures can be designed and manufactured to provide multiple modes of information, so that the structures have the capabilities for intelligent sensing, environmental adaptation and multi-functionality. The challenges for building such a structural state sensing system and some solutions to address the challenges are also discussed in the paper.

  19. Multifunctional nanowire scaffolds for neural tissue engineering applications

    NASA Astrophysics Data System (ADS)

    Bechara, Samuel Leo

    Unlike other regions of the body, the nervous system is extremely vulnerable to damage and injury because it has a limited ability to self-repair. Over 250,000 people in the United States have spinal cord injuries and due to the complicated pathophysiology of such injuries, there are few options available for functional regeneration of the spinal column. Furthermore, peripheral nerve damage is troublingly common in the United States, with an estimated 200,000 patients treated surgically each year. The current gold standard in treatment for peripheral nerve damage is a nerve autograft. This technique was pioneered over 45 years ago, but suffers from a major drawback. By transecting a nerve from another part of the body, function is regained at the expense of destroying a nerve connection elsewhere. Because of these issues, the investigation of different materials for regenerating nervous tissue is necessary. This work examines multi-functional nanowire scaffolds to provide physical and chemical guidance cues to neural stem cells to enhance cellular activity from a biomedical engineering perspective. These multi-functional scaffolds include a unique nanowire nano-topography to provide physical cues to guide cellular adhesion. The nanowires were then coated with an electrically conductive polymer to further enhance cellular activity. Finally, nerve growth factor was conjugated to the surface of the scaffolds to provide chemical cues for the neural stem cells. The results in this work suggest that these multifunctional nanowire scaffolds could be used in vivo to repair nervous system tissue.

  20. Magnetic-encoded fluorescent multifunctional nanospheres for simultaneous multicomponent analysis.

    PubMed

    Song, Erqun; Han, Weiye; Li, Jingrong; Jiang, Yunfei; Cheng, Dan; Song, Yang; Zhang, Pu; Tan, Weihong

    2014-10-01

    In this study, magnetic-encoded fluorescent (CdTe/Fe3O4)@SiO2 multifunctional nanospheres were constructed by adjusting the initial concentration of Fe3O4 in a fabrication process based on reverse microemulsion. The resultant multifunctional nanospheres were characterized by transmission electron microscopy, X-ray diffraction measurements, fluorescence spectrophotometry, and vibrating sample magnetometry. They showed good fluorescence properties, gradient magnetic susceptibility (weak, moderate, and strong), and easy biofunctionalization for biomolecules, such as immunoglobulin G (IgG), protein, and antibody. Then the capture efficiency of the (CdTe/Fe3O4)@SiO2 nanospheres were investigated by using the fluorophore-labeled IgG-conjugated nanospheres as a model. Further studies demonstrated the ability of these (CdTe/Fe3O4)@SiO2 multifunctional nanospheres to accomplish sequentially magnetic separation, capture, and fluorescent detection for each corresponding antigen of CA125, AFP, and CEA with a detection limit of 20 KU/L, 10 ng/mL, and 5 ng/mL, respectively, from a mixed sample under a certain external magnetic field within a few minutes. The strategy of combining magnetic-encoding-based separation and fluorescence-based detection proposed in this study shows great potential to achieve easy, rapid, economical, and near-simultaneous multicomponent separation and analysis for a variety of targets such as drugs, biomarkers, pathogens, and so on. PMID:25197942

  1. Strain Sensitivity in Single Walled Carbon Nanotubes for Multifunctional Materials

    NASA Technical Reports Server (NTRS)

    Heath, D. M. (Technical Monitor); Smits, Jan M., VI

    2005-01-01

    Single walled carbon nanotubes represent the future of structural aerospace vehicle systems due to their unparalleled strength characteristics and demonstrated multifunctionality. This multifunctionality rises from the CNT's unique capabilities for both metallic and semiconducting electron transport, electron spin polarizability, and band gap modulation under strain. By incorporating the use of electric field alignment and various lithography techniques, a single wall carbon nanotube (SWNT) test bed for measurement of conductivity/strain relationships has been developed. Nanotubes are deposited at specified locations through dielectrophoresis. The circuit is designed such that the central, current carrying section of the nanotube is exposed to enable atomic force microscopy and manipulation in situ while the transport properties of the junction are monitored. By applying this methodology to sensor development a flexible single wall carbon nanotube (SWNT) based strain sensitive device has been developed. Studies of tensile testing of the flexible SWNT device vs conductivity are also presented, demonstrating the feasibility of using single walled HiPCO (high-pressure carbon monoxide) carbon nanotubes as strain sensing agents in a multi-functional materials system.

  2. Mercury Contamination: Review of a Residential Response.

    PubMed

    Thompson, Marcella R

    2012-02-01

    A residential elemental mercury contamination incident in Rhode Island resulted in the evacuation of an entire apartment complex.To develop recommendations for improved response, all response-related documents were examined; personnel involved in the response were interviewed; policies and procedures were reviewed; and environmental monitoring data were compiled from specific phases of the response for analysis of effect.A significant challenge of responding to residential elemental mercury contamination lies in communicating risk to residents affected py a HazMat spill. An ongoing, open and honest dialogue is emphasized where concerns of the public are heard and addressed, particularly when establishing and/or modifying policies and procedures for responding to residential elemental mercury contamination. PMID:23436951

  3. Dynamic management of integrated residential energy systems

    NASA Astrophysics Data System (ADS)

    Muratori, Matteo

    This study combines principles of energy systems engineering and statistics to develop integrated models of residential energy use in the United States, to include residential recharging of electric vehicles. These models can be used by government, policymakers, and the utility industry to provide answers and guidance regarding the future of the U.S. energy system. Currently, electric power generation must match the total demand at each instant, following seasonal patterns and instantaneous fluctuations. Thus, one of the biggest drivers of costs and capacity requirement is the electricity demand that occurs during peak periods. These peak periods require utility companies to maintain operational capacity that often is underutilized, outdated, expensive, and inefficient. In light of this, flattening the demand curve has long been recognized as an effective way of cutting the cost of producing electricity and increasing overall efficiency. The problem is exacerbated by expected widespread adoption of non-dispatchable renewable power generation. The intermittent nature of renewable resources and their non-dispatchability substantially limit the ability of electric power generation of adapting to the fluctuating demand. Smart grid technologies and demand response programs are proposed as a technical solution to make the electric power demand more flexible and able to adapt to power generation. Residential demand response programs offer different incentives and benefits to consumers in response to their flexibility in the timing of their electricity consumption. Understanding interactions between new and existing energy technologies, and policy impacts therein, is key to driving sustainable energy use and economic growth. Comprehensive and accurate models of the next-generation power system allow for understanding the effects of new energy technologies on the power system infrastructure, and can be used to guide policy, technology, and economic decisions. This

  4. Solar Photovoltaic Financing: Residential Sector Deployment

    SciTech Connect

    Coughlin, J.; Cory, K.

    2009-03-01

    This report presents the information that homeowners and policy makers need to facilitate PV financing at the residential level. The full range of cash payments, bill savings, and tax incentives is covered, as well as potentially available solar attribute payments. Traditional financing is also compared to innovative solutions, many of which are borrowed from the commercial sector. Together, these mechanisms are critical for making the economic case for a residential PV installation, given its high upfront costs. Unfortunately, these programs are presently limited to select locations around the country. By calling attention to these innovative initiatives, this report aims to help policy makers consider greater adoption of these models to benefit homeowners interested installing a residential PV system.

  5. Low back pain in Hispanic residential carpenters☆

    PubMed Central

    Gilkey, David P.; Enebo, Brian A.; Keefe, Thomas J.; Vela Acosta, Martha Soledad; Hautaluoma, Jacob E.; Bigelow, Philip L.; Rosecrance, John; Herron, Robert E.

    2007-01-01

    Abstract Objective Low back pain (LBP) is a leading cause of lost work time and has been recognized as America's number one workplace safety challenge. Low back pain is occurring at epidemic proportions among construction workers, and minority populations have been underinvestigated for risk of back injury. This project investigated the multiple potential risk factors for occupational LBP among Hispanic residential carpenters. Methods This investigation evaluated 241 Hispanic residential framing carpenters. Data for this study were collected using a 91-question survey. End points of interest included point, annual, and lifetime prevalence of LBP. Results Nineteen percent of respondents reported they had an episode of LBP in their lifetime. Conclusions Hispanic residential carpenters reported less than expected prevalence of LBP compared with non-Hispanic counterparts in the same trade and location. Job tasks and personal and workplace risk factors, including psychological and morphological characteristics, affect the prevalence of LBP among Hispanic framing carpenters. PMID:19674688

  6. Evaluation of Updated Standard Operating Proceduresfor Residential Exposure Assessment

    EPA Science Inventory

    The Standard Operating Procedures for Residential Exposure Assessment (i.e., Residential SOPs) is a set of standard instructions for estimating exposure resulting from various non-occupational pesticide uses including lawn and garden care, foggers, and pet treatments.

  7. Benchmark data for identifying multi-functional types of membrane proteins.

    PubMed

    Wan, Shibiao; Mak, Man-Wai; Kung, Sun-Yuan

    2016-09-01

    Identifying membrane proteins and their multi-functional types is an indispensable yet challenging topic in proteomics and bioinformatics. In this article, we provide data that are used for training and testing Mem-ADSVM (Wan et al., 2016. "Mem-ADSVM: a two-layer multi-label predictor for identifying multi-functional types of membrane proteins" [1]), a two-layer multi-label predictor for predicting multi-functional types of membrane proteins. PMID:27294176

  8. 24 CFR 40.2 - Definition of “residential structure”.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OWNED RESIDENTIAL STRUCTURES § 40.2 Definition of “residential structure”. (a) As used in this part, the term residential structure means a residential structure (other than a privately owned residential structure and a residential structure on a military reservation): (1) Constructed or altered by or on...

  9. 24 CFR 40.2 - Definition of “residential structure”.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OWNED RESIDENTIAL STRUCTURES § 40.2 Definition of “residential structure”. (a) As used in this part, the term residential structure means a residential structure (other than a privately owned residential structure and a residential structure on a military reservation): (1) Constructed or altered by or on...

  10. 24 CFR 40.2 - Definition of “residential structure”.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OWNED RESIDENTIAL STRUCTURES § 40.2 Definition of “residential structure”. (a) As used in this part, the term residential structure means a residential structure (other than a privately owned residential structure and a residential structure on a military reservation): (1) Constructed or altered by or on...

  11. 24 CFR 40.2 - Definition of “residential structure”.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... OWNED RESIDENTIAL STRUCTURES § 40.2 Definition of “residential structure”. (a) As used in this part, the term residential structure means a residential structure (other than a privately owned residential structure and a residential structure on a military reservation): (1) Constructed or altered by or on...

  12. Strategy Guideline: High Performance Residential Lighting

    SciTech Connect

    Holton, J.

    2012-02-01

    The Strategy Guideline: High Performance Residential Lighting has been developed to provide a tool for the understanding and application of high performance lighting in the home. The high performance lighting strategies featured in this guide are drawn from recent advances in commercial lighting for application to typical spaces found in residential buildings. This guide offers strategies to greatly reduce lighting energy use through the application of high quality fluorescent and light emitting diode (LED) technologies. It is important to note that these strategies not only save energy in the home but also serve to satisfy the homeowner's expectations for high quality lighting.

  13. Nitrate production and availability in residential soils.

    PubMed

    Raciti, Steve M; Groffman, Peter M; Jenkins, Jennifer C; Pouyat, Richard V; Fahey, Timothy J; Pickett, Steward T A; Cadenasso, Mary L

    2011-10-01

    The rapid increase in residential land area in the United States has raised concern about water pollution associated with nitrogen fertilizers. Nitrate (NO3-) is the form of reactive N that is most susceptible to leaching and runoff; thus, a more thorough understanding of nitrification and NO3(-) availability is needed if we are to accurately predict the consequences of residential expansion for water quality. In particular, there have been few assessments of how the land use history, housing density, and age of residential soils influence NO3(-) pools and fluxes, especially at depth. In this study, we used 1 m deep soil cores to evaluate potential net nitrification and mineralization, microbial respiration and biomass, and soil NO3(-) and NH4+ pools in 32 residential home lawns that differed by previous land use and age, but had similar soil types. These were compared to eight forested reference sites with similar soils. Our results suggest that a change to residential land use has increased pools and production of reactive N, which has clear implications for water quality in the region. However, the results contradict the common assumption that NO3(-) production and availability is dramatically higher in residential soils than in forests in general. While net nitrification (128.6 +/- 15.5 mg m(-2) d(-1) vs. 4.7 +/- 2.3 mg m(-2) d(-1); mean +/- SE) and exchangeable NO3(-) (3.8 +/- 0.5 g/m2 vs. 0.7 +/- 0.3 g/m2) were significantly higher in residential soils than in forest soils in this study, these measures of NO3(-) production and availability were still notably low, comparable to deciduous forest stands in other studies. A second unexpected result was that current homeowner management practices were not predictive of NO3(-) availability or production. This may reflect the transient availability of inorganic N after fertilizer application. Higher housing density and a history of agricultural land use were predictors of greater NO3(-) availability in residential

  14. 10 CFR 429.17 - Residential water heaters.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Residential water heaters. 429.17 Section 429.17 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.17 Residential water heaters. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to residential water...

  15. 10 CFR 429.17 - Residential water heaters.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Residential water heaters. 429.17 Section 429.17 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.17 Residential water heaters. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to residential water...

  16. 12 CFR 541.16 - Improved residential real estate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false Improved residential real estate. 541.16 Section 541.16 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 541.16 Improved residential real estate. The term improved residential real estate...

  17. Residential Group Care Quarterly. Volume 5, Number 3, Winter 2005

    ERIC Educational Resources Information Center

    Michael, Jennifer, Ed.

    2005-01-01

    This issue of "Residential Group Care Quarterly" contains the following articles: (1) "Promising Practices for Adequately Funding and Reimbursing Residential Services" (Lloyd Bullard); (2) "Closing the Gender Gap" (Erin Andersen); (3) "Residential Child Care: Guidelines for Physical Techniques, Crisis Prevention, and Management" (Kurk Lalemand);…

  18. Residential Group Care Quarterly. Volume 6, Number 2, Fall 2005

    ERIC Educational Resources Information Center

    Michael, Jennifer, Ed.

    2005-01-01

    This issue of "Residential Group Care Quarterly" contains the following articles: (1) "CWLA's Position on Residential Care"; (2) "The View of Adolescent Life: Perceptions and Realities" ( Lisa Moore Willis); (3) "Assessing Youth Preferences for Adult Behavior in Residential Care: A Replication" (Jack T. Bowers, III, Robert J. Jones, Gary D.…

  19. Benefits of Residential and Nonresidential Youth Summer Camps.

    ERIC Educational Resources Information Center

    Ross, David M.; Driver, B. L.

    1988-01-01

    Describes survey made as part of Youth Conservation Corps evaluation. Compares personal benefits of residential camping with benefits of nonresidential camps. Concludes residential participants benefited in different ways and to greater extent than nonresidential campers. Residential camping benefits measurable at least nine months after…

  20. 10 CFR 429.17 - Residential water heaters.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Residential water heaters. 429.17 Section 429.17 Energy... COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.17 Residential water heaters. (a) Sampling plan for selection of units for testing. (1) The requirements of § 429.11 are applicable to residential water...

  1. Residential Preferences and Moving Behavior: A Family Life Cycle Analysis.

    ERIC Educational Resources Information Center

    McAuley, William J.; Nutty, Cheri L.

    The relationship of family life cycle changes to housing preferences and residential mobility is examined. Two residential decision-making issues are explored in detail--how family life cycle stages influence what people view as important to their choice of residential setting and what individuals at different family life cycle stages view as the…

  2. Youth Departing from Residential Care: A Gender Comparison

    ERIC Educational Resources Information Center

    Griffith, Annette K.; Trout, Alexandra L.; Chmelka, M. Beth; Farmer, Elizabeth M. Z.; Epstein, Michael H.; Reid, Robert; Huefner, Jonathan C.; Orduna, Debbie

    2009-01-01

    Although females represent almost half of all youth involved in residential care in the US, very little is known about this population. In order to examine differences in characteristics of male (n = 308) and female (n = 180) youth departing from residential care, data were collected on 488 youth from a large residential treatment facility in the…

  3. National Residential Efficiency Measures Database Aimed at Reducing Risk for Residential Retrofit Industry (Fact Sheet)

    SciTech Connect

    Not Available

    2012-01-01

    This technical highlight describes NREL research to develop a publicly available database of energy retrofit measures containing performance characteristics and cost estimates for nearly 3,000 measures. Researchers at the U.S. Department of Energy (DOE) National Renewable Energy Laboratory (NREL) have developed the National Residential Efficiency Measures Database, a public database that characterizes the performance and costs of common residential energy efficiency measures. The data are available for use in software programs that evaluate cost-effective retrofit measures to improve the energy efficiency of residential buildings. The database provides a single, consistent source of current data for DOE and private-sector energy audit and simulation software tools and the retrofit industry. The database will reduce risk for residential retrofit industry stakeholders by providing a central, publicly vetted source of up-to-date information.

  4. MODEL FOR INSTANTANEOUS RESIDENTIAL WATER DEMANDS

    EPA Science Inventory

    Residential wateer use is visualized as a customer-server interaction often encountered in queueing theory. Individual customers are assumed to arrive according to a nonhomogeneous Poisson process, then engage water servers for random lengths of time. Busy servers are assumed t...

  5. Risk Factors for Rural Residential Fires

    ERIC Educational Resources Information Center

    Allareddy, Veerasathpurush; Peek-Asa, Corinne; Yang, Jingzhen; Zwerling, Craig

    2007-01-01

    Context and Purpose: Rural households report high fire-related mortality and injury rates, but few studies have examined the risk factors for fires. This study aims to identify occupant and household characteristics that are associated with residential fires in a rural cohort. Methods: Of 1,005 households contacted in a single rural county, 691…

  6. MODEL FOR INSTANTANEOUS RESIDENTIAL WATER DEMANDS

    EPA Science Inventory

    Residential water use is visualized as a customer-server interaction often encountered in queuing theory. ndividual customers are assumed to arrive according to a nonhomogeneous Poisson process, then engage water servers for random lengths of time. usy servers are assumed to draw...

  7. Development of a Residential Integrated Ventilation Controller

    SciTech Connect

    Staff Scientist; Walker, Iain; Sherman, Max; Dickerhoff, Darryl

    2011-12-01

    The goal of this study was to develop a Residential Integrated Ventilation Controller (RIVEC) to reduce the energy impact of required mechanical ventilation by 20percent, maintain or improve indoor air quality and provide demand response benefits. This represents potential energy savings of about 140 GWh of electricity and 83 million therms of natural gas as well as proportional peak savings in California. The RIVEC controller is intended to meet the 2008 Title 24 requirements for residential ventilation as well as taking into account the issues of outdoor conditions, other ventilation devices (including economizers), peak demand concerns and occupant preferences. The controller is designed to manage all the residential ventilation systems that are currently available. A key innovation in this controller is the ability to implement the concept of efficacy and intermittent ventilation which allows time shifting of ventilation. Using this approach ventilation can be shifted away from times of high cost or high outdoor pollution towards times when it is cheaper and more effective. Simulations, based on the ones used to develop the new residential ventilation requirements for the California Buildings Energy code, were used to further define the specific criteria and strategies needed for the controller. These simulations provide estimates of the energy, peak power and contaminant improvement possible for different California climates for the various ventilation systems. Results from a field test of the prototype controller corroborate the predicted performance.

  8. Residential and Light Commercial HVAC. Teacher Edition.

    ERIC Educational Resources Information Center

    Stephenson, David; Fulkerson, Dan, Ed.

    This curriculum guide contains 18 units of instruction for a competency-based course in residential and light commercial heating, ventilating, and air conditioning (HVAC). Introductory materials include a competency profile and an instructional/task analysis that correlates job training with related information for this course. Each instructional…

  9. Distinctively American: The Residential Liberal Arts College.

    ERIC Educational Resources Information Center

    Koblik, Steven, Ed.; Graubard, Stephen R., Ed.

    This book seeks to examine the residential liberal arts colleges as an institution, from its role in the lives of students, to its value as a form of education. It explores the threat faced by liberal arts colleges, as well as the transformative role, but positive and negative, information technology will play in future development and survival.…

  10. Enhancing Residential Treatment for Drug Court Participants

    ERIC Educational Resources Information Center

    Koob, Jeff; Brocato, Jo; Kleinpeter, Christine

    2011-01-01

    In this study, the authors describe and evaluate the impact of increased access to residential treatment added to traditional drug court services in Orange County, California, with a goal of increasing program retention, successful completion, and graduation rates for a high-risk drug offender population participating in drug court between January…

  11. Maintaining Cultural Integrity in Residential Treatment

    ERIC Educational Resources Information Center

    Pazaratz, Don

    2005-01-01

    Cross-cultural residential placement of children and adolescents requires careful attention to the youth's culture of origin, so that the delivery of the treatment service is respectful of his or her way of life. Cultural protection in treatment facilities, as a principle, ensures that the traditions, symbols, values, norms, and the worldview, as…

  12. Residential solar-heating/cooling system

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Report documents progress of residential solar-heating and cooling system development program at 5-month mark of anticipated 17-month program. System design has been completed, and development and component testing has been initiated. Report includes diagrams, operation overview, optimization studies of subcomponents, and marketing plans for system.

  13. Current Research Trends in Residential Life.

    ERIC Educational Resources Information Center

    Ware, Thomas E., Jr.; Miller, Michael T.

    This paper reviews the literature on the role that campus residential life plays in the life of college students. While some researchers have concluded that living on-campus or off-campus has little affect on student academic achievement (Bliming, 1989; Bowman and Partin, 1993), others have expressed that on-campus living produces students with…

  14. A Curriculum for the Residential Educable Child.

    ERIC Educational Resources Information Center

    Southern Wisconsin Colony and Training School, Union Grove.

    Organized so that each teacher may use some latitude in planning teaching approaches, the guide describes the sequential curriculum used with educable mentally retarded children in a residential setting. Arithmetic, language arts, science, and social studies are outlined separately for preprimary, primary, and intermediate levels. Vocational units…

  15. Residential Carpentry Series. Duty Task List.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This document contains the occupational duty/task lists for nine occupations in the residential carpentry series. Each occupation is divided into a number of duties. A separate page for each duty in the occupation lists the tasks in that duty along with its code number and columns to indicate whether that particular duty has been taught and to…

  16. Small Child Care Facilities in Residential Areas.

    ERIC Educational Resources Information Center

    Giegerich & Associates, Inc., Rockville, MD.

    One part of a three-part investigation prepared for the Montgomery County Planning Board in Silver Spring, Maryland, this study addresses planning and site planning issues arising from the location of child care facilities in residential settings. The study, which emphasizes homes and centers which care for 7 to 20 children, provides a detailed…

  17. Residential mobility breeds familiarity-seeking.

    PubMed

    Oishi, Shigehiro; Miao, Felicity F; Koo, Minkyung; Kisling, Jason; Ratliff, Kate A

    2012-01-01

    Why are American landscapes (e.g., housing developments, shopping malls) so uniform, despite the well-known American penchant for independence and uniqueness? We propose that this paradox can be explained by American mobility: Residential mobility fosters familiarity-seeking and familiarity-liking, while allowing individuals to pursue their personal goals and desires. We reason that people are drawn to familiar objects (e.g., familiar, national chain stores) when they move. We conducted 5 studies to test this idea at the levels of society, individuals, and situations. We found that (a) national chain stores do better in residentially mobile places than in residentially stable places (controlling for other economic and demographic factors; Study 1); (b) individuals who have moved a lot prefer familiar, national chain stores to unfamiliar stores (Studies 2a and 2b); and (c) a residential mobility mindset enhances the mere exposure and familiarity-liking effect (Studies 4 and 5). In Study 5, we demonstrated that the link between mobility and familiarity-liking was mediated by anxiety evoked by mobility. PMID:21843015

  18. Guidelines for Transferring Residential Courses into Web

    ERIC Educational Resources Information Center

    Tüzün, Hakan; Çinar, Murat

    2016-01-01

    This study shared unique design experiences by examining the process of transferring residential courses to the Web, and proposed a design model for individuals who want to transfer their courses into this environment. The formative research method was used in the study, and two project teams' processes of putting courses, which were being taught…

  19. The Residential Center: Corrections in the Community.

    ERIC Educational Resources Information Center

    Bureau of Prisons (Dept. of Justice), Washington, DC.

    Sometimes called "halfway houses," the residential centers provide correctional services needed in the transition of selected offenders from prison terms to productive roles in society. Their task includes building solid ties between the offender and the community, integrating him into community life, restoring family ties, and obtaining…

  20. Residential Facilities for the Mentally Retarded.

    ERIC Educational Resources Information Center

    Baumeister, Alfred A., Ed.; Butterfield, Earl, Ed.

    The handbook on residential institutions, for professionals and students in the field of mental retardation, attempts to interpret the institution as a part of the culture which it serves, avoiding emotional responses but suggesting formulas for change. Characteristics of contemporary institutions for the mentally retarded are examined and…

  1. Consumer Decision Rules and Residential Finance.

    ERIC Educational Resources Information Center

    Brandt, Jeanette A.; Jaffe, Austin J.

    1979-01-01

    As guidelines for residential financing, the authors compare different approaches to understanding and figuring the costs of home ownership: the relation of income to house price and housing costs, interest rate, and mortgage term. Instead of the traditional method, they recommend the time value of money approach. (MF)

  2. Older Adults' Perceptions of Residential Relocation.

    ERIC Educational Resources Information Center

    Kampfe, Charlene M.

    2002-01-01

    This study is a companion to a larger study of older adults who had made residential relocations that involved moving from one level of independence to another level. The current study examined the degree to which older individuals perceived their moves to be important, controllable, stressful, disruptive, and positive. (Author)

  3. Intentions and Expectations in Differential Residential Selection

    ERIC Educational Resources Information Center

    Michelson, William; And Others

    1973-01-01

    This paper summarizes intentions and expectations in differential residential selection among families who had chose to move. Wives appear at face value to assess alternatives in the selection process rationally, to be aware of limitations in housing and location they will experience, and to have expectations about behavioral changes consistant…

  4. Residential GSHPs: Efficiency With Short Payback Periods

    SciTech Connect

    Cooperman, Alissa; Dieckmann, John; Brodrick, James

    2012-04-30

    This article discusses ground source heat pumps (GSHPs) for residential application as an alternative to conventional HVAC systems. A listing of current space heating energy sources are presented which are then followed by a technology overview as advances have made GSHPs more efficient. The article concludes with potential energy savings offered by GSHPs and a brief market overview.

  5. ANALYSIS OF EMISSIONS FROM RESIDENTIAL OIL FURNACES

    EPA Science Inventory

    The paper gives results of a series of emission tests on a residential oil furnace to determine emissions from two types of burners. umber of analyses were performed on the emissions, including total mass, filterable particulate, total oil furnaces tested by the EPA in Roanoke, V...

  6. Chapter 21: Residential Lighting Evaluation Protocol

    SciTech Connect

    Dimetrosky, S.; Parkinson, K.; Lieb, N.

    2015-02-01

    In recent years, residential lighting has represented a significant share of ratepayer-funded energy-efficiency electricity savings. Utilities have achieved the majority of these savings by promoting the purchase and installation of compact fluorescent lamps (CFLs), both standard 'twister' bulbs and specialty CFLs such as reflectors, A-Lamps, globes, and dimmable lights.

  7. Assuring Residential Quality: Issues, Approaches and Instruments.

    ERIC Educational Resources Information Center

    Bersani, Hank A., Jr.

    This report begins with discussion of several issues in the field of quality assurance in residential services for individuals with developmental disabilities. The issues include definitions of key terms, the role of ideology, major types of quality assurance, and dimensions of quality assurance. The report takes the position that primary values…

  8. Laboratory Performance Testing of Residential Dehumidifiers (Presentation)

    SciTech Connect

    Winkler, J.

    2012-03-01

    Six residential vapor compression cycle dehumidifiers spanning the available range of capacities and efficiencies were tested in the National Renewable Energy Laboratory's Heating, Ventilating, and Air-Conditioning Systems Laboratory. Each was tested under a wide range of indoor air conditions to facilitate the development of performance curves for use in whole-building simulation tools.

  9. CHAMELEON AUTOMATED RESIDENTIAL ENERGY MANAGEMENT SYSTEM

    EPA Science Inventory

    The expected output of the project will be an experimentally determined Chameleon specification. The expected outcomes will include 1) a set of guidelines for implementing Chameleon in residential structures from both a retrofit and original design perspective and 2) a cost a...

  10. Residential Mobility among the Rural Poor.

    ERIC Educational Resources Information Center

    Fitchen, Janet M.

    1994-01-01

    The frequency of short-distance residential moves in poor rural New York counties was much greater than nationally, driven by scarce affordable housing and changes in personal and household situations. Higher frequency movement was associated with younger age, fewer children, and weaker social support networks. Discusses impacts of high mobility…

  11. House Work: Jobs in Residential Upkeep

    ERIC Educational Resources Information Center

    Bierer, Amy

    2011-01-01

    For many people, domestic bliss does not involve cleaning, home repairs, or yard work. That doesn't mean that their vision of a happy home involves a dirty, broken-down house with an unkempt yard. It simply means that they prefer to pay others to do the grittier tasks of residential upkeep. And in doing so, they create employment opportunities for…

  12. Residential Camping for At Risk Preschoolers.

    ERIC Educational Resources Information Center

    Kosberg, Bernard; Mellins, Claude A.; Pubentz, Jennifer L.

    A combination of experiential education and residential camping can have positive effects on preschool children with emotional, behavioral, and learning problems. Preschool Prep at Ramapo Anchorage Camp (Rhinebeck, New York) was developed to meet the specific needs of high-risk children aged 4-6. Many of the children come from unsafe urban…

  13. Multifunctional Collaborative Modeling and Analysis Methods in Engineering Science

    NASA Technical Reports Server (NTRS)

    Ransom, Jonathan B.; Broduer, Steve (Technical Monitor)

    2001-01-01

    Engineers are challenged to produce better designs in less time and for less cost. Hence, to investigate novel and revolutionary design concepts, accurate, high-fidelity results must be assimilated rapidly into the design, analysis, and simulation process. This assimilation should consider diverse mathematical modeling and multi-discipline interactions necessitated by concepts exploiting advanced materials and structures. Integrated high-fidelity methods with diverse engineering applications provide the enabling technologies to assimilate these high-fidelity, multi-disciplinary results rapidly at an early stage in the design. These integrated methods must be multifunctional, collaborative, and applicable to the general field of engineering science and mechanics. Multifunctional methodologies and analysis procedures are formulated for interfacing diverse subdomain idealizations including multi-fidelity modeling methods and multi-discipline analysis methods. These methods, based on the method of weighted residuals, ensure accurate compatibility of primary and secondary variables across the subdomain interfaces. Methods are developed using diverse mathematical modeling (i.e., finite difference and finite element methods) and multi-fidelity modeling among the subdomains. Several benchmark scalar-field and vector-field problems in engineering science are presented with extensions to multidisciplinary problems. Results for all problems presented are in overall good agreement with the exact analytical solution or the reference numerical solution. Based on the results, the integrated modeling approach using the finite element method for multi-fidelity discretization among the subdomains is identified as most robust. The multiple-method approach is advantageous when interfacing diverse disciplines in which each of the method's strengths are utilized. The multifunctional methodology presented provides an effective mechanism by which domains with diverse idealizations are

  14. A method for measuring dermal exposure to multifunctional acrylates.

    PubMed

    Surakka, J; Johnsson, S; Rosén, G; Lindh, T; Fischer, T

    1999-12-01

    UV-curable acrylates are used increasingly for coating wood surfaces in the furniture industry. One of the active components, tripropylene glycol diacrylate (TPGDA), is known to be both an allergen and irritant to the skin. Methods to measure dermal exposure to skin irritants and allergens, such as acrylates, are insufficient for exposure assessment and there is none for this compound. The aim of this investigation was to develop a skin and surface sampling method, based on tape stripping, and a gas chromatographic method for quantitative analysis for assessing occupational skin exposure to multifunctional acrylates. Twelve adhesives were tested for their efficiency to remove TPGDA and UV-coating from a glass surface, the skin of guinea pigs and human volunteers employing the tape-stripping method in order to find the best performing tape. Variables that affect removal efficiency such as the applied dose and its retention time on the skin, tape adhesion time on the skin, and the number of strippings required to detect the contaminant from the skin were studied. Fixomull tape performed the best during sampling and analysis and had the most consistent removal efficiencies for the studied substances. The average removal efficiency with a single stripping at the 2 microliters TPGDA exposed skin sites was 85% (RSD = 14.1), and for UV-resin exposed sites 63% (RSD = 20.2). The results indicated that this method can be used for measuring dermal exposure to multifunctional acrylates efficiently, accurately, and economically. This method provides a sensitive and powerful tool for the assessment of dermal exposure to multifunctional acrylates both from the skin and from other contaminated surfaces in occupational field settings. PMID:11529185

  15. Integration of Multifunctional Epitaxial Oxide Heterostructures with Si(001)

    NASA Astrophysics Data System (ADS)

    Singamaneni, Srinivasa Rao; Prater, John; Narayan, Jay

    Multifunctional heterostructures exhibit a wide range of functional properties, including colossal magneto-resistance, multiferroic behavior, and spin, charge, and orbital ordering. However, putting this functionality to work remains a challenge. To date, most of the previous works reported in the literature have dealt with heterostructures deposited on closely lattice matched (using lattice matching epitaxy-LME) insulating substrates such as DyScO3, NdGaO3, MgO, SrTiO3 and MBE-grown STO buffered Si(100). This presentation discusses the major advances in the integration of multifunctional oxide materials onto ubiquitous silicon semiconductor platform reported1-6 in the recent past by the presenting authors using a novel thin film growth approach, called `domain matching epitaxy'(DME), which minimizes the strain and nucleation of unwanted defects. The DME paradigm has been used across the large misfit scale (7-25%). Of particular interest, thin film heterostructures including two-phase multiferroics such as BiFeO3(BFO)/La0.7Sr0.3MnO3 (LSMO), BaTiO3(BTO)/LSMO, and LSMO/SrRuO3(SRO). These significant materials advancements may herald a flurry of exciting new advances in CMOS-compatible multifunctional devices.1S. S. Rao,et al.,Nano Letters 13, 5814 (2013); J. Appl. Phys., 116, 094103 (2014); J. Appl. Phys., 116, 224104 (2014); J. Appl. Phys., 117, 17D908 (2015); 5J. Appl. Phys., 117, 17B711 (2015); 6Current Opinion in Solid State and Materials Science. 19, 301-304 (2015).

  16. Cyanate ester-nanoparticle composites as multifunctional structural capacitors

    NASA Astrophysics Data System (ADS)

    De Leon, J. Eliseo

    An important goal of engineering is to increase the energy density of electrical energy storage devices used to deliver power onboard mobile platforms. Equally important is the goal to reduce the overall mass of the vehicles transporting these devices to achieve increased fuel and cost efficiency. One approach to meeting both these objectives is to develop multifunctional systems that serve as both energy storage and load bearing structural devices. Multifunctional devices consist of constituents that individually perform a subset of the overall desired functions. However, the synergy achieved by the combination of each constituent's characteristics allows for system-level benefits that cannot be achieved by simply optimizing the separate subsystems. We investigated multifunctional systems consisting of light weight polymer matrix and high dielectric constant fillers to achieve these objectives. The monomer of bisphenol E cyanate ester exhibited excellent processing ability because of its low room temperature viscosity. Additionally, the fully cured thermoset demonstrated excellent thermal stability, specific strength and stiffness. Fillers, including multi-walled carbon nanotubes, nanometer scale barium titanate and nanometer scale calcium copper titanate, offer high dielectric constants that raised the effective dielectric constant of the polymer matrix composite. The combination of high epsilon'and high dielectric strength produce high energy density components exhibiting increased electrical energy storage. Mechanical (load bearing) improvements of the PMCs were attributed to covalently bonded nanometer and micrometer sized filler particles, as well as the continuous glass fiber, integrated into the resin systems which increased the structural characteristics of the cured composites. Breakdown voltage tests and dynamic mechanical analysis were employed to demonstrate that precise combinations of these constituents, under the proper processing conditions, can

  17. Multifunctional hybrid Fe2O3-Au nanoparticles for efficient plasmonic heating

    DOE PAGESBeta

    Murph, Simona E. Hunyadi; Larsen, George K.; Lascola, Robert J.

    2016-02-20

    We describe the synthesis and properties of multifunctional Fe2O3-Au nanoparticles produced by a wet chemical approach and investigate their photothermal properties using laser irradiation. Here, the composite Fe2O3-Au nanoparticles retain the properties of both materials, creating a multifunctional structure with excellent magnetic and plasmonic properties.

  18. Recreation and Agroforestry: Examining New Dimensions of Multifunctionality in Family Farms

    ERIC Educational Resources Information Center

    Barbieri, Carla; Valdivia, Corinne

    2010-01-01

    Multifunctionality serves as an analytical framework to recognize many services that farms provide to their surrounding communities and society. This study explores an often overlooked dimension of multifunctionality by examining different recreational services provided by landowners in Missouri and analyzing the relationship between recreational…

  19. Multifunctional bulk plasma source based on discharge with electron injection

    SciTech Connect

    Klimov, A. S.; Medovnik, A. V.; Tyunkov, A. V.; Savkin, K. P.; Shandrikov, M. V.; Vizir, A. V.

    2013-01-15

    A bulk plasma source, based on a high-current dc glow discharge with electron injection, is described. Electron injection and some special design features of the plasma arc emitter provide a plasma source with very long periods between maintenance down-times and a long overall lifetime. The source uses a sectioned sputter-electrode array with six individual sputter targets, each of which can be independently biased. This discharge assembly configuration provides multifunctional operation, including plasma generation from different gases (argon, nitrogen, oxygen, acetylene) and deposition of composite metal nitride and oxide coatings.

  20. Multifunctional additives for automotive gasolines based on oxyethylated compounds

    SciTech Connect

    Lykov, O.P.; Vishnyakova, T.P.; Tsygan, L.V.; Emel'yanov, V.E.

    1987-03-01

    The authors have investigated various oil-soluble nonionic surfactants with different degrees of oxyethylation as multifunctional additives for gasolines. The following products were taken for oxyethylation: C/sub 17/-C/sub 20/ synthetic fatty acids; concentrate of isocarboxylic and unsaturated acids segregated from C/sub 17/-C/sub 20/ SFA by cold acetone; technical C/sub 10/-C/sub 18/ alkylsalicylic acids; products from the condensation of AC acids with C/sub 10/-C/sub 16/ aliphatic amines; primary aliphatic amines.

  1. Application of multi-function display and control technology

    NASA Technical Reports Server (NTRS)

    Spiger, R. J.; Farrell, R. J.; Holcomb, G. A.

    1982-01-01

    The NASA orbiter spacecraft incorporates a complex array of systems, displays, and controls. The incorporation of discrete dedicated controls into a multifunction display and control system (MFDCS) offers the potential for savings in weight, power, panel space, and crew training time. Technology identified as applicable to a MFDCS is applied to the orbiter orbital maneuvering system (OMS) and the electrical power distribution and control system (EPDCS) to derive concepts for a MFDCS design. Several concepts of varying degrees of performance and complexity are discussed and a suggested concept for further development is presented in greater detail. Both the hardware and software aspects and the human factors considerations of the designs are included.

  2. The Rocketdyne Multifunction Tester. Part 1: Test Method

    NASA Technical Reports Server (NTRS)

    Murphy, Brian T.; Scharrer, Joseph K.; Sutton, Robert F.

    1991-01-01

    The Rocketdyne Multifunction Tester is a general purpose test apparatus which utilizes axial and radial magnetic bearings as shaft excitation devices. The tester is modular in design so that different seal and bearing packages can be tested on the same test stand. The tester will be used for rotordynamic coefficient extraction, as well as life and fluid/material compatibility evaluations. Use of a magnetic bearing as a shaft excitation device opens up many possibilities for shaft excitation and rotordynamic coefficient extraction. In addition to describing the basic apparatus, some of the excitation and extraction methods are described. Some of the excitation methods to be discussed include random, aperiodic, harmonic, impulse and chirp.

  3. Multifunctional Hydrogel Microparticles by Polymer-Assisted Photolithography.

    PubMed

    Li, Bin; He, Muhan; Ramirez, Lisa; George, Justin; Wang, Jun

    2016-02-17

    Although standard lithography has been the most common technique in micropatterning, ironically it has not been adopted to produce multifunctional hydrogel microparticles, which are highly useful for bioassays. We address this issue by developing a negative photoresist-like polymer system, which is basically comprised of polyethylene glycol (PEG) triacrylate as cross-linking units and long-chain polyvinylpyrrolidone (PVP) as the supporting scaffold. We leverage standard lithography to manufacture multilayer microparticles that are intrinsically hydrophilic, low-autofluorescent, and chemically reactive. The versatility of the microparticles is demonstrated to be color-encoded, pore-controllable, bioactive, and potentially used as a DNA bioassay. PMID:26821173

  4. Survey of multi-function display and control technology

    NASA Technical Reports Server (NTRS)

    Spiger, R. J.; Farrell, R. J.; Tonkin, M. H.

    1982-01-01

    The NASA orbiter spacecraft incorporates a complex array of systems, displays and controls. The incorporation of discrete dedicated controls into a multi-function display and control system (MFDCS) offers the potential for savings in weight, power, panel space and crew training time. The technology applicable to the development of a MFDCS for orbiter application is surveyed. Technology thought to be applicable presently or in the next five years is highlighted. Areas discussed include display media, data handling and processing, controls and operator interactions and the human factors considerations which are involved in a MFDCS design. Several examples of applicable MFDCS technology are described.

  5. Multifunctional clickable and protein-repellent magnetic silica nanoparticles

    NASA Astrophysics Data System (ADS)

    Estupiñán, Diego; Bannwarth, Markus B.; Mylon, Steven E.; Landfester, Katharina; Muñoz-Espí, Rafael; Crespy, Daniel

    2016-01-01

    Silica nanoparticles are versatile materials whose physicochemical surface properties can be precisely adjusted. Because it is possible to combine several functionalities in a single carrier, silica-based materials are excellent candidates for biomedical applications. However, the functionality of the nanoparticles can get lost upon exposure to biological media due to uncontrolled biomolecule adsorption. Therefore, it is important to develop strategies that reduce non-specific protein-particle interactions without losing the introduced surface functionality. Herein, organosilane chemistry is employed to produce magnetic silica nanoparticles bearing differing amounts of amino and alkene functional groups on their surface as orthogonally addressable chemical functionalities. Simultaneously, a short-chain zwitterion is added to decrease the non-specific adsorption of biomolecules on the nanoparticles surface. The multifunctional particles display reduced protein adsorption after incubation in undiluted fetal bovine serum as well as in single protein solutions (serum albumin and lysozyme). Besides, the particles retain their capacity to selectively react with biomolecules. Thus, they can be covalently bio-functionalized with an antibody by means of orthogonal click reactions. These features make the described multifunctional silica nanoparticles a promising system for the study of surface interactions with biomolecules, targeting, and bio-sensing.Silica nanoparticles are versatile materials whose physicochemical surface properties can be precisely adjusted. Because it is possible to combine several functionalities in a single carrier, silica-based materials are excellent candidates for biomedical applications. However, the functionality of the nanoparticles can get lost upon exposure to biological media due to uncontrolled biomolecule adsorption. Therefore, it is important to develop strategies that reduce non-specific protein-particle interactions without losing the

  6. Development of a Miniature Multifunctional GPS Receiver for Space Applications

    NASA Astrophysics Data System (ADS)

    Miyano, Tomoyuki; Ishijima, Yoshiyuki; Kumagai, Susumu

    This paper presents the development of a miniature multifunctional GPS receiver at NASDA. The design and implementation method for a spaceborne GPS receiver has been investigated, and a breadboard model of a parallel signal search system incorporating matched filtering, an essential technique for next-generation GPS receivers, has been manufactured. The time to acquisition (TTA) of a GPS signal was measured on the breadboard model using a GPS simulator. The test results of the trial product show that TTA is within 60 msec, and time to first fix (TTFF) of the navigation calculation in a low-altitude orbit is within 5.3 min in the worst-case scenario.

  7. Finishing Titanium Alloy Cutting Zone Analysis Via Multifunction Measuring System

    NASA Astrophysics Data System (ADS)

    Andrej, Czán; Michal, Šajgalík; Drbúl, Mário; Holubják, Jozef; Mrázik, Jozef; Babík, Ondrej; Zaušková, Lucia; Piešová, Marianna

    2015-12-01

    With the development of automotive, aerospace and biomedical industry, there is higher demand for exotic alloys, often based on titanium or nickel, though they are hard to machine. Therefore, it is essential to thoroughly understand their behavior during machining. Processes in the cutting zone of said materials are due to the complexity and dynamics defined by specific models. These include some deviations, thus it is essential to improve machining observation methodology, so exhibited errors and deviations are minimal or none. Based on the observations, multifunction measuring system has been designed, which allows simultaneous observation of characteristics such as e.g. cutting forces, deformations and thermal spread without uninterrupting machining process.

  8. [The development of multifunction intravenous infusion quantitative packaging device].

    PubMed

    Zhao, Shufang; Li, Ruihua; Shen, Lianhong

    2012-11-01

    Aimed at tackling the compatibility issues arising from the drug reaction in intravenous infusion tube, we developed a simple, suitable and multi-function intravenous infusion tube for the special use for rescuing critical patients, the elderly, children etc. Each drug in a transfusion process can be filtered to realize quantitative packet and packet delivery. Thus, the drugs in the infusion tube are prevented from meeting with each other. No overlap, no particle pollution occurred. Stable performance and accurate dosage are maintained. As a result safety is ensured during drug delivery. PMID:23461118

  9. Mussel-inspired surface chemistry for multifunctional coatings.

    PubMed

    Lee, Haeshin; Dellatore, Shara M; Miller, William M; Messersmith, Phillip B

    2007-10-19

    We report a method to form multifunctional polymer coatings through simple dip-coating of objects in an aqueous solution of dopamine. Inspired by the composition of adhesive proteins in mussels, we used dopamine self-polymerization to form thin, surface-adherent polydopamine films onto a wide range of inorganic and organic materials, including noble metals, oxides, polymers, semiconductors, and ceramics. Secondary reactions can be used to create a variety of ad-layers, including self-assembled monolayers through deposition of long-chain molecular building blocks, metal films by electroless metallization, and bioinert and bioactive surfaces via grafting of macromolecules. PMID:17947576

  10. [Hissing--a multifunctional and interspecific animal signal].

    PubMed

    Silaeva, O L

    1996-01-01

    Hissing signals were studied in various groups of animals: insects, reptiles, mammals, and birds. Hissing was analyzed using a computer-based acoustic analyzer KAPROS-01. General similarities of hissing were noted for representatives of taxonomically remote orders and classes, as well as evident structural differences, not always related to the absence of taxonomic relatedness of the given species. Bioacoustic parallelisms of hissing were shown, which are based on threatening signals from animals with ecological weapons, such as poison, sharp teeth and claws, etc. Multifunctional and interspecific patterns of hissing were noted as well as its ecological-communicative role in biocenotic relations between animals of different groups. PMID:9004902

  11. Dynamic management of integrated residential energy systems

    NASA Astrophysics Data System (ADS)

    Muratori, Matteo

    This study combines principles of energy systems engineering and statistics to develop integrated models of residential energy use in the United States, to include residential recharging of electric vehicles. These models can be used by government, policymakers, and the utility industry to provide answers and guidance regarding the future of the U.S. energy system. Currently, electric power generation must match the total demand at each instant, following seasonal patterns and instantaneous fluctuations. Thus, one of the biggest drivers of costs and capacity requirement is the electricity demand that occurs during peak periods. These peak periods require utility companies to maintain operational capacity that often is underutilized, outdated, expensive, and inefficient. In light of this, flattening the demand curve has long been recognized as an effective way of cutting the cost of producing electricity and increasing overall efficiency. The problem is exacerbated by expected widespread adoption of non-dispatchable renewable power generation. The intermittent nature of renewable resources and their non-dispatchability substantially limit the ability of electric power generation of adapting to the fluctuating demand. Smart grid technologies and demand response programs are proposed as a technical solution to make the electric power demand more flexible and able to adapt to power generation. Residential demand response programs offer different incentives and benefits to consumers in response to their flexibility in the timing of their electricity consumption. Understanding interactions between new and existing energy technologies, and policy impacts therein, is key to driving sustainable energy use and economic growth. Comprehensive and accurate models of the next-generation power system allow for understanding the effects of new energy technologies on the power system infrastructure, and can be used to guide policy, technology, and economic decisions. This

  12. Multifunctional gold nanoparticles for diagnosis and therapy of disease

    PubMed Central

    Mieszawska, Aneta J.; Mulder, Willem J. M.; Fayad, Zahi A.

    2013-01-01

    Gold nanoparticles (AuNPs) have a number of physical properties that make them appealing for medical applications. For example, the attenuation of X-rays by gold nanoparticles has led to their use in computed tomography imaging and as adjuvants for radiotherapy. AuNPs have numerous other applications in imaging, therapy and diagnostic systems. The advanced state of synthetic chemistry of gold nanoparticles offers precise control over physicochemical and optical properties. Furthermore gold cores are inert and are considered to be biocompatible and non-toxic. The surface of gold nanoparticles can easily be modified for a specific application and ligands for targeting, drugs or biocompatible coatings can be introduced. AuNPs can be incorporated into larger structures such as polymeric nanoparticles or liposomes that deliver large payloads for enhanced diagnostic applications, efficiently encapsulate drugs for concurrent therapy or add additional imaging labels. This array of features has led to the afore-mentioned applications in biomedical fields, but more recently in approaches where multifunctional gold nanoparticles are used for multiple methods, such as concurrent diagnosis and therapy, so called theranostics. The following review covers basic principles and recent findings in gold nanoparticle applications for imaging, therapy and diagnostics, with a focus on reports of multifunctional AuNPs. PMID:23360440

  13. PREFACE: Workshop on Oxide Materials 2014: Novel Multifunctional Properties

    NASA Astrophysics Data System (ADS)

    Gómez, M. E.; Lopera, W.

    2015-07-01

    The 2014 Workshop on Oxide Materials: Novel Multifunctional Properties was held in Cali, Colombia, from September 15 to September 19 on the campus of Universidad del Valle. It was a great privilege to have had this workshop in Cali after the first workshop on oxide materials commemorating the first centennial of the discovery of the superconductivity in 2011. The meeting gathered an audience of 80 participants, 10 invited speakers with two or three plenary talks each, 20 short oral contributions, two poster sessions with 20 presentations each. This proceedings volume contains papers reported at the conference. The Proceedings of the 2014 Workshop on Oxide Materials: Novel Multifunctional Properties were edited by Maria Elena Gomez and Wilson Lopera with the assistance of Carlos William Sanchez and Albert Ortiz as copy editor. We are grateful for the financial support from COLCIENCIAS through research project COLCIENCIAS-UNIVALLE contract 002/2013; Universidad de Valle through Professor Ivan Ramos, Rector; the Faculty of Science with Professor Jaime Cantera, Dean; the Center of Excellence on Novel Materials with Professor Pedro Prieto, Director; ICETEX, and INTECO Ltda. Further details about the conference, including details of the invited speakers and plenary sessions are available in the PDF. Maria Elena Gómez, Editor Wilson Lopera, Editor

  14. Multifunctional Nanoparticles for Brain Tumor Diagnosis and Therapy

    PubMed Central

    Cheng, Yu; Morshed, Ramin; Auffinger, Brenda; Tobias, Alex L.; Lesniak, Maciej S.

    2013-01-01

    Brain tumors are a diverse group of neoplasms that often carry a poor prognosis for patients. Despite tremendous efforts to develop diagnostic tools and therapeutic avenues, the treatment of brain tumors remains a formidable challenge in the field of neuro-oncology. Physiological barriers including the blood-brain barrier result in insufficient accumulation of therapeutic agents at the site of a tumor, preventing adequate destruction of malignant cells. Furthermore, there is a need for improvements in brain tumor imaging to allow for better characterization and delineation of tumors, visualization of malignant tissue during surgery, and tracking of response to chemotherapy and radiotherapy. Multifunctional nanoparticles offer the potential to improve upon many of these issues and may lead to breakthroughs in brain tumor management. In this review, we discuss the diagnostic and therapeutic applications of nanoparticles for brain tumors with an emphasis on innovative approaches in tumor targeting, tumor imaging, and therapeutic agent delivery. Clinically feasible nanoparticle administration strategies for brain tumor patients are also examined. Furthermore, we address the barriers towards clinical implementation of multifunctional nanoparticles in the context of brain tumor management. PMID:24060923

  15. The small light multi-function integrated remote sensing system

    NASA Astrophysics Data System (ADS)

    Zhang, Weiwei; Lin, Zhaorong; Yao, Yigang

    2015-08-01

    With the development of network information, the era of big data is coming, and this has high demand to the information quantity and the diversity of the remote sensing images. Currently the available remote sensing system focuses on the convenience and the celerity of the acquiring images, and lacking the remote sensing system which can acquire the image with the diversity and large amount of information. In this paper, a new small light multifunction integrated remote sensing and the remote sensing information network system of multi-sensor are proposed to meet the new developing requirements of the current network information. The small light multi-function integrated remote sensing system consists of a load platform, the integrated sensor system, the airborne control system, the stabilized platform, the transmission system and the ground processing system. The components, function and the principle of the system are introduced, and the key technologies of the integrated remote sensing system are analyzed, in the last the applications of the system are described in order to make a contribution to the industrialization of the big data remote sensing.

  16. Multifunctional Aptamer-miRNA Conjugates for Targeted Cancer Therapy

    PubMed Central

    Esposito, Carla L; Cerchia, Laura; Catuogno, Silvia; De Vita, Gennaro; Dassie, Justin P; Santamaria, Gianluca; Swiderski, Piotr; Condorelli, Gerolama; Giangrande, Paloma H; de Franciscis, Vittorio

    2014-01-01

    While microRNAs (miRNAs) clearly regulate multiple pathways integral to disease development and progression, the lack of safe and reliable means for specific delivery of miRNAs to target tissues represents a major obstacle to their broad therapeutic application. Our objective was to explore the use of nucleic acid aptamers as carriers for cell-targeted delivery of a miRNA with tumor suppressor function, let-7g. Using an aptamer that binds to and antagonizes the oncogenic receptor tyrosine kinase Axl (GL21.T), here we describe the development of aptamer-miRNA conjugates as multifunctional molecules that inhibit the growth of Axl-expressing tumors. We conjugated the let-7g miRNA to GL21.T and demonstrate selective delivery to target cells, processing by the RNA interference machinery, and silencing of let-7g target genes. Importantly, the multifunctional conjugate reduced tumor growth in a xenograft model of lung adenocarcinoma. Therefore, our data establish aptamer-miRNA conjugates as a novel tool for targeted delivery of miRNAs with therapeutic potential. PMID:24441398

  17. Multifunctionality of chiton biomineralized armor with an integrated visual system

    SciTech Connect

    Li, Ling; Connors, Matthew; Kolle, Mathias; England, Grant; Speiser, Daniel; Xiao, Xianghui; Aizenberg, Joanna; Ortiz, Christine

    2015-11-20

    Nature provides a multitude of examples of multifunctional structural materials. There are often trade-offs in these materials because few of them are equally well suited for multiple tasks. One such example is the biomineralized armor of the chiton Acanthopleura granulata, which incorporates an integrated sensory system that includes hundreds of eyes with aragonite-based lens. Here, we used optical experiments to demonstrate directly, for the first time, that these microscopic, mineralized lenses are able to form images. Furthermore, our experiments revealed that the optical performance of these polycrystalline lenses is enhanced by the reduction of spherical aberration through the shape of the lens and that birefringence scattering is minimized by the use of relatively large, co-aligned grains (~10 μm as compared to ~1 μm in the non-eye regions). Additionally, we used multi-scale mechanical testing techniques to show that A. granulata’s lenses are an integral component of its biomineralized armor, but that both the intrinsic and overall mechanical properties of the lenses are compromised as compared to the primary solid regions of the armor plates. Our results demonstrate that as the size, complexity, and functionality of the integrated sensory elements increases, the local mechanical performance of the armor decreases. But, A. granulata has evolved several strategies to compensate for its local mechanical vulnerabilities to form a multifunctional system with co-optimized overall optical and structural functions.

  18. A novel multifunctional NiTi/Ag hierarchical composite

    PubMed Central

    Hao, Shijie; Cui, Lishan; Jiang, Jiang; Guo, Fangmin; Xiao, Xianghui; Jiang, Daqiang; Yu, Cun; Chen, Zonghai; Zhou, Hua; Wang, Yandong; Liu, YuZi; Brown, Dennis E.; Ren, Yang

    2014-01-01

    Creating multifunctional materials is an eternal goal of mankind. As the properties of monolithic materials are necessary limited, one route to extending them is to create a composite by combining contrasting materials. The potential of this approach is neatly illustrated by the formation of nature materials where contrasting components are combined in sophisticated hierarchical designs. In this study, inspired by the hierarchical structure of the tendon, we fabricated a novel composite by subtly combining two contrasting components: NiTi shape-memory alloy and Ag. The composite exhibits simultaneously exceptional mechanical properties of high strength, good superelasticity and high mechanical damping, and remarkable functional properties of high electric conductivity, high visibility under fluoroscopy and excellent thermal-driven ability. All of these result from the effective-synergy between the NiTi and Ag components, and place the composite in a unique position in the properties chart of all known structural-functional materials providing new opportunities for innovative electrical, mechanical and biomedical applications. Furthermore, this work may open new avenues for designing and fabricating advanced multifunctional materials by subtly combining contrasting multi-components. PMID:24919945

  19. Multifunctional hydrogel nano-probes for atomic force microscopy

    PubMed Central

    Lee, Jae Seol; Song, Jungki; Kim, Seong Oh; Kim, Seokbeom; Lee, Wooju; Jackman, Joshua A.; Kim, Dongchoul; Cho, Nam-Joon; Lee, Jungchul

    2016-01-01

    Since the invention of the atomic force microscope (AFM) three decades ago, there have been numerous advances in its measurement capabilities. Curiously, throughout these developments, the fundamental nature of the force-sensing probe—the key actuating element—has remained largely unchanged. It is produced by long-established microfabrication etching strategies and typically composed of silicon-based materials. Here, we report a new class of photopolymerizable hydrogel nano-probes that are produced by bottom-up fabrication with compressible replica moulding. The hydrogel probes demonstrate excellent capabilities for AFM imaging and force measurement applications while enabling programmable, multifunctional capabilities based on compositionally adjustable mechanical properties and facile encapsulation of various nanomaterials. Taken together, the simple, fast and affordable manufacturing route and multifunctional capabilities of hydrogel AFM nano-probes highlight the potential of soft matter mechanical transducers in nanotechnology applications. The fabrication scheme can also be readily utilized to prepare hydrogel cantilevers, including in parallel arrays, for nanomechanical sensor devices. PMID:27199165

  20. 3D Printing for Spacecraft Multi-Functional Structures

    NASA Astrophysics Data System (ADS)

    Roddy, P. A.; Huang, C. Y.; Lyke, J.; Baur, J.; Durstock, M.; MacDonald, E.

    2013-12-01

    Three-dimensional printing, more formally Additive Manufacturing (AM), is being explored by groups worldwide for use in space missions, but we recognize the amazing potential of this emerging technology to produce space weather environmental sensors at costs commensurate with declining research budgets. We present here a plan to go substantially beyond the novelty stage of this technology by developing a foundation for using AM in high-assurance space system missions. Our two-pronged approach involves (1) a disciplined investigation of material properties and reliability (electrical, mechanical, radiation) of AM and (2) the extension of this knowledge to make complex structures that can exploit the advantages of AM. We address the design, manufacture, and optimization of multifunctional space structures using multi-physics design methods, integrated computational models, and AM. Integrated multifunctional structures have significant advantage in flexibility, size, weight, and power in comparison to formally attached elements, but their design and fabrication can be complex. The complexity and range in element shape, processing method, material properties and vehicle integration make this an ideal problem to advance the current state of the art methods for multiphysics mechanism design and strengthening AM processing science.

  1. Multifunctional hydroxyapatite nanofibers and microbelts as drug carriers.

    PubMed

    Hou, Zhiyao; Yang, Piaoping; Lian, Hongzhou; Wang, Lili; Zhang, Cuimiao; Li, Chunxia; Chai, Ruitao; Cheng, Ziyong; Lin, Jun

    2009-07-13

    Luminescent, mesoporous, and bioactive europium-doped hydroxyapatite (HAp:Eu(3+)) nanofibers and microbelts have been prepared by a combination of sol-gel and electrospinning processes with a cationic surfactant as template. The obtained multifunctional hydroxyapatite nanofibers and microbelts, which have mesoporous structure and red luminescence, were tested as drug carriers by investigating their drug-storage/release properties with ibuprofen (IBU) as model drug. X-ray diffraction, scanning electron microscopy (SEM), transmission electron microscopy (TEM), high-resolution (HR) TEM, FTIR spectroscopy, N(2) adsorption/desorption, photoluminescence (PL) spectra, and UV/Vis spectroscopy were used to characterize the structural, morphological, textural, and optical properties of the resulting samples. The results reveal that the multifunctional hydroxyapatites exhibit irregular mesostructure, and have fiberlike and beltlike morphologies with sizes of several hundred nanometers in width and several millimeters in length. The IBU-loaded HAp:Eu(3+) system shows red luminescence of Eu(3+) ((5)D(0)-(7)F(0,1,2)) under UV irradiation and controlled release of IBU. In addition, the emission intensity of Eu(3+) in the drug carrier system varies with the released amount of IBU, and thus drug release can be easily tracked and monitored by the change in luminescence intensity. PMID:19496099

  2. A Multifunctional Smart Coating for Autonomous Corrosion Control

    NASA Technical Reports Server (NTRS)

    Calle, Luz Marina; Buhrow, Jerry W.; Jolley, Scott T.

    2012-01-01

    Corrosion is a destructive process that often causes failure in metallic components and structures. Protective coatings are the most commonly used method of corrosion control. However, progressively stricter environmental regulations have resulted in the ban of many commercially available corrosion protective coatings due to the harmful effects of their solvents or corrosion inhibitors. This work concerns the development of a multifunctional, smart coating for the autonomous control of corrosion. This coating is being developed to have the inherent ability to detect the chemical changes associated with the onset of corrosion and respond autonomously to control it. The multi-functionality of the coating is based on micro-encapsulation technology specifically designed for corrosion control applications. This design has, in addition to all the advantages of other existing microcapsules designs, the corrosion controlled release function that allows the delivery of corrosion indicators and inhibitors on demand only when and where needed. Corrosion indicators as well as corrosion inhibitors have been incorporated into microcapsules, blended into several paint systems, and tested for corrosion detection and protection efficacy. This

  3. Multifunctionality of chiton biomineralized armor with an integrated visual system

    DOE PAGESBeta

    Li, Ling; Connors, Matthew; Kolle, Mathias; England, Grant; Speiser, Daniel; Xiao, Xianghui; Aizenberg, Joanna; Ortiz, Christine

    2015-11-20

    Nature provides a multitude of examples of multifunctional structural materials. There are often trade-offs in these materials because few of them are equally well suited for multiple tasks. One such example is the biomineralized armor of the chiton Acanthopleura granulata, which incorporates an integrated sensory system that includes hundreds of eyes with aragonite-based lens. Here, we used optical experiments to demonstrate directly, for the first time, that these microscopic, mineralized lenses are able to form images. Furthermore, our experiments revealed that the optical performance of these polycrystalline lenses is enhanced by the reduction of spherical aberration through the shape ofmore » the lens and that birefringence scattering is minimized by the use of relatively large, co-aligned grains (~10 μm as compared to ~1 μm in the non-eye regions). Additionally, we used multi-scale mechanical testing techniques to show that A. granulata’s lenses are an integral component of its biomineralized armor, but that both the intrinsic and overall mechanical properties of the lenses are compromised as compared to the primary solid regions of the armor plates. Our results demonstrate that as the size, complexity, and functionality of the integrated sensory elements increases, the local mechanical performance of the armor decreases. But, A. granulata has evolved several strategies to compensate for its local mechanical vulnerabilities to form a multifunctional system with co-optimized overall optical and structural functions.« less

  4. Multifunctional magnetic rotator for micro and nanorheological studies

    PubMed Central

    Tokarev, Alexander; Aprelev, Alexey; Zakharov, Mikhail N.; Korneva, Guzeliya; Gogotsi, Yury; Kornev, Konstantin G.

    2012-01-01

    We report on the development of a multifunctional magnetic rotator that has been built and used during the last five years by two groups from Clemson and Drexel Universities studying the rheological properties of microdroplets. This magnetic rotator allows one to generate rotating magnetic fields in a broad frequency band, from hertz to tens kilohertz. We illustrate its flexibility and robustness by conducting the rheological studies of simple and polymeric fluids at the nano and microscale. First we reproduce a temperature-dependent viscosity of a synthetic oil used as a viscosity standard. Magnetic rotational spectroscopy with suspended nickel nanorods was used in these studies. As a second example, we converted the magnetic rotator into a pump with precise controlled flow modulation. Using multiwalled carbon nanotubes, we were able to estimate the shear modulus of sickle hemoglobin polymer. We believe that this multifunctional magnetic system will be useful not only for micro and nanorheological studies, but it will find much broader applications requiring remote controlled manipulation of micro and nanoobjects. PMID:22755665

  5. Multifunctional nanoparticles for brain tumor imaging and therapy.

    PubMed

    Cheng, Yu; Morshed, Ramin A; Auffinger, Brenda; Tobias, Alex L; Lesniak, Maciej S

    2014-02-01

    Brain tumors are a diverse group of neoplasms that often carry a poor prognosis for patients. Despite tremendous efforts to develop diagnostic tools and therapeutic avenues, the treatment of brain tumors remains a formidable challenge in the field of neuro-oncology. Physiological barriers including the blood-brain barrier result in insufficient accumulation of therapeutic agents at the site of a tumor, preventing adequate destruction of malignant cells. Furthermore, there is a need for improvements in brain tumor imaging to allow for better characterization and delineation of tumors, visualization of malignant tissue during surgery, and tracking of response to chemotherapy and radiotherapy. Multifunctional nanoparticles offer the potential to improve upon many of these issues and may lead to breakthroughs in brain tumor management. In this review, we discuss the diagnostic and therapeutic applications of nanoparticles for brain tumors with an emphasis on innovative approaches in tumor targeting, tumor imaging, and therapeutic agent delivery. Clinically feasible nanoparticle administration strategies for brain tumor patients are also examined. Furthermore, we address the barriers towards clinical implementation of multifunctional nanoparticles in the context of brain tumor management. PMID:24060923

  6. Multifunctional hyperbranched glycoconjugated polymers based on natural aminoglycosides.

    PubMed

    Chen, Mingsheng; Hu, Mei; Wang, Dali; Wang, Guojian; Zhu, Xinyuan; Yan, Deyue; Sun, Jian

    2012-06-20

    Multifunctional gene vectors with high transfection, low cytotoxicity, and good antitumor and antibacterial activities were prepared from natural aminoglycosides. Through the Michael-addition polymerization of gentamycin and N,N'-methylenebisacrylamide, cationic hyperbranched glycoconjugated polymers were synthesized, and their physical and chemical properties were analyzed by FTIR, (1)H NMR, (13)C NMR, GPC, ζ-potential, and acid-base titration techniques. The cytotoxicity of these hyperbranched glycoconjugated polycations was low because of the hydrolysis of degradable glycosidic and amide linkages in acid conditions. Owing to the presence of various primary, secondary, and tertiary amines in the polymers, hyperbranched glycoconjugated polymers showed high buffering capacity and strong DNA condensation ability, resulting in the high transfection efficiency. In the meantime, due to the introduction of natural aminoglycosides into the polymeric backbone, the resultant hyperbranched glycoconjugated polymers inhibited the growth of cancer cells and bacteria efficiently. Combining the gene transfection, antitumor, and antibacterial abilities together, the multifunctional hyperbranched glycoconjugated polymers based on natural aminoglycosides may play an important role in protecting cancer patients from bacterial infections. PMID:22591322

  7. Multifunctional Single-Site Catalysts for Alkoxycarbonylation of Terminal Alkynes.

    PubMed

    Chen, Xingkun; Zhu, Hejun; Wang, Wenlong; Du, Hong; Wang, Tao; Yan, Li; Hu, Xiangping; Ding, Yunjie

    2016-09-01

    A multifunctional copolymer (PyPPh2 -SO3 H@porous organic polymers, POPs) was prepared by combining acidic groups and heterogeneous P,N ligands through the copolymerization of vinyl-functionalized 2-pyridyldiphenylphosphine (2-PyPPh2 ) and p-styrene sulfonic acid under solvothermal conditions. The morphology and chemical structure of the copolymer were evaluated using a series of characterization techniques. Compared with traditional homogeneous Pd(OAc)2 /2-PyPPh2 / p-toluenesulfonic acid catalyst, the copolymer supported palladium catalyst (Pd-PyPPh2 -SO3 H@POPs) exhibited higher activity for alkoxycarbonylation of terminal alkynes under the same conditions. This phenomenon could be attributed to the synergistic effect between the single-site Pd centers, 2-PyPPh2 ligands, and SO3 H groups, the outstanding swelling properties as well as the high enrichment of the reactant concentration by the porous catalyst. In addition, the catalyst could be reused at least 4 times without any apparent loss of activity. The excellent catalytic reactivity and good recycling properties make it an attractive catalyst for industrial applications. This work paves the way for advanced multifunctional porous organic polymers as a new type of platform for heterogeneous catalysis in the future. PMID:27530651

  8. Electrospray of multifunctional microparticles for image-guided drug delivery

    NASA Astrophysics Data System (ADS)

    Zhang, Leilei; Yan, Yan; Mena, Joshua; Sun, Jingjing; Letson, Alan; Roberts, Cynthia; Zhou, Chuanqing; Chai, Xinyu; Ren, Qiushi; Xu, Ronald

    2012-03-01

    Anti-VEGF therapies have been widely explored for the management of posterior ocular disease, like neovascular age-related macular degeneration (AMD). Loading anti-VEGF therapies in biodegradable microparticles may enable sustained drug release and improved therapeutic outcome. However, existing microfabrication processes such as double emulsification produce drug-loaded microparticles with low encapsulation rate and poor antibody bioactivity. To overcome these limitations, we fabricate multifunctional microparticles by both single needle and coaxial needle electrospray. The experimental setup for the process includes flat-end syringe needles (both single needle and coaxial needle), high voltage power supplies, and syringe pumps. Microparticles are formed by an electrical field between the needles and the ground electrode. Droplet size and morphology are controlled by multiple process parameters and material properties, such as flow rate and applied voltage. The droplets are collected and freezing dried to obtain multifunctional microparticles. Fluorescent beads encapsulated poly(DL-lactide-co-glycolide) acid (PLGA) microparticles are injected into rabbits eyes through intravitreal injection to test the biodegradable time of microparticles.

  9. A multifunctional joint angle sensor with measurement adaptability.

    PubMed

    Quan, Wei; Wang, Hua; Liu, Datong

    2013-01-01

    The paper presents a multifunctional joint sensor with measurement adaptability for biological engineering applications, such as gait analysis, gesture recognition, etc. The adaptability is embodied in both static and dynamic environment measurements, both of body pose and in motion capture. Its multifunctional capabilities lay in its ability of simultaneous measurement of multiple degrees of freedom (MDOF) with a single sensor to reduce system complexity. The basic working mode enables 2DOF spatial angle measurement over big ranges and stands out for its applications on different joints of different individuals without recalibration. The optional advanced working mode enables an additional DOF measurement for various applications. By employing corrugated tube as the main body, the sensor is also characterized as flexible and wearable with less restraints. MDOF variations are converted to linear displacements of the sensing elements. The simple reconstruction algorithm and small outputs volume are capable of providing real-time angles and long-term monitoring. The performance assessment of the built prototype is promising enough to indicate the feasibility of the sensor. PMID:24217353

  10. A novel multifunctional NiTi/Ag hierarchical composite

    NASA Astrophysics Data System (ADS)

    Hao, Shijie; Cui, Lishan; Jiang, Jiang; Guo, Fangmin; Xiao, Xianghui; Jiang, Daqiang; Yu, Cun; Chen, Zonghai; Zhou, Hua; Wang, Yandong; Liu, Yuzi; Brown, Dennis E.; Ren, Yang

    2014-06-01

    Creating multifunctional materials is an eternal goal of mankind. As the properties of monolithic materials are necessary limited, one route to extending them is to create a composite by combining contrasting materials. The potential of this approach is neatly illustrated by the formation of nature materials where contrasting components are combined in sophisticated hierarchical designs. In this study, inspired by the hierarchical structure of the tendon, we fabricated a novel composite by subtly combining two contrasting components: NiTi shape-memory alloy and Ag. The composite exhibits simultaneously exceptional mechanical properties of high strength, good superelasticity and high mechanical damping, and remarkable functional properties of high electric conductivity, high visibility under fluoroscopy and excellent thermal-driven ability. All of these result from the effective-synergy between the NiTi and Ag components, and place the composite in a unique position in the properties chart of all known structural-functional materials providing new opportunities for innovative electrical, mechanical and biomedical applications. Furthermore, this work may open new avenues for designing and fabricating advanced multifunctional materials by subtly combining contrasting multi-components.

  11. Multifunctional hydrogel nano-probes for atomic force microscopy

    NASA Astrophysics Data System (ADS)

    Lee, Jae Seol; Song, Jungki; Kim, Seong Oh; Kim, Seokbeom; Lee, Wooju; Jackman, Joshua A.; Kim, Dongchoul; Cho, Nam-Joon; Lee, Jungchul

    2016-05-01

    Since the invention of the atomic force microscope (AFM) three decades ago, there have been numerous advances in its measurement capabilities. Curiously, throughout these developments, the fundamental nature of the force-sensing probe--the key actuating element--has remained largely unchanged. It is produced by long-established microfabrication etching strategies and typically composed of silicon-based materials. Here, we report a new class of photopolymerizable hydrogel nano-probes that are produced by bottom-up fabrication with compressible replica moulding. The hydrogel probes demonstrate excellent capabilities for AFM imaging and force measurement applications while enabling programmable, multifunctional capabilities based on compositionally adjustable mechanical properties and facile encapsulation of various nanomaterials. Taken together, the simple, fast and affordable manufacturing route and multifunctional capabilities of hydrogel AFM nano-probes highlight the potential of soft matter mechanical transducers in nanotechnology applications. The fabrication scheme can also be readily utilized to prepare hydrogel cantilevers, including in parallel arrays, for nanomechanical sensor devices.

  12. Multifunctional Upconversion-Magnetic Hybrid Nanostructured Materials: Synthesis and Bioapplications

    PubMed Central

    Li, Xiaomin; Zhao, Dongyuan; Zhang, Fan

    2013-01-01

    The combination of nanotechnology and biology has developed into an emerging research area: nano-biotechnology. Upconversion nanoparticles (UCNPs) have attracted a great deal of attention in bioapplications due to their high chemical stability, low toxicity, and high signal-to-noise ratio. Magnetic nanoparticles (MNPs) are also well-established nanomaterials that offer controlled size, ability to be manipulated externally, and enhancement of contrast in magnetic resonance imaging (MRI). As a result, these nanoparticles could have many applications in biology and medicine, including protein purification, drug delivery, and medical imaging. Because of the potential benefits of multimodal functionality in biomedical applications, researchers would like to design and fabricate multifunctional upconversion-magnetic hybrid nanostructured materials. The hybrid nanostructures, which combine UCNPs with MNPs, exhibit upconversion fluorescence alongside superparamagnetism property. Such structures could provide a platform for enhanced bioimaging and controlled drug delivery. We expect that the combination of unique structural characteristics and integrated functions of multifunctional upconversion-magnetic nanoparticles will attract increasing research interest and could lead to new opportunities in nano-bioapplications. PMID:23650477

  13. Multifunctional polymer nano-composite based superhydrophobic surface

    NASA Astrophysics Data System (ADS)

    Maitra, Tanmoy; Asthana, Ashish; Buchel, Robert; Tiwari, Manish K.; Poulikakos, Dimos

    2014-11-01

    Superhydrophobic surfaces become desirable in plethora of applications in engineering fields, automobile industry, construction industries to name a few. Typical fabrication of superhydrophobic surface consists of two steps: first is to create rough morphology on the substrate of interest, followed by coating of low energy molecules. However, typical exception of the above fabrication technique would be direct coating of functional polymer nanocomposites on substrate where superhydrophobicity is needed. Also in this case, the use of different nanoparticles in the polymer matrix can be exploited to impart multi-functional properties to the superhydrophobic coatings. Herein, different carbon nanoparticles like graphene nanoplatelets (GNP), carbon nanotubes (CNT) and carbon black (CB) are used in fluropolymer matrix to prepare superhydrophobic coatings. The multi-functional properties of coatings are enhanced by combining two different carbon fillers in the matrix. The aforementioned superhydrophobic coatings have shown high electrical conductivity and excellent droplet meniscus impalement resistance. Simultaneous superhydrophobic and oleophillic character of the above coating is used to separate mineral oil and water through filtration of their mixture. Swiss National Science Foundation (SNF) Grant 200021_135479.

  14. Synthesis of High-Molecular-Weight Multifunctional Glycerol Polyhydroxyurethanes PHUs.

    PubMed

    Nohra, Bassam; Candy, Laure; Blanco, Jean-François; Raoul, Yann; Mouloungui, Zéphirin

    2016-01-01

    Glycerol carbonate acrylate is a 5-membered cyclic carbonate synthesized from glycerol that is used as a chemical coupling agent and has proven highly suitable for use in the synthesis of multifunctional polyhydroxyurethanes (PHUs). The multifunctionality of the structure of PHUs is determined by the density of the carbon-amine groups generated by the Aza-Michael reaction and that of the urethane groups and adjacent primary and secondary hydroxyl groups generated by aminolysis. Glycerol carbonate acrylate is polymerized with polyfunctional mono-, di-, tri, and tetra-amines, by type-AB polyaddition, either in bulk or in solution, through stepwise or one-pot reaction strategies in the absence of added catalysts. These approaches result in the generation of linear, interchain, and crosslinked structures, through the polyaddition of linear and branched amines to the ethylene and cyclic carbonate sites of glycerol carbonate acrylate. The resulting collection of organic molecules gives rise to polyethylene amino ester PHUs with a high molar mass, exceeding 20,000 g·mol(-1), with uniform dispersity. PMID:27626401

  15. Multifunctional magnetic rotator for micro and nanorheological studies

    NASA Astrophysics Data System (ADS)

    Tokarev, Alexander; Aprelev, Alexey; Zakharov, Mikhail N.; Korneva, Guzeliya; Gogotsi, Yury; Kornev, Konstantin G.

    2012-06-01

    We report on the development of a multifunctional magnetic rotator that has been built and used during the last five years by two groups from Clemson and Drexel Universities studying the rheological properties of microdroplets. This magnetic rotator allows one to generate rotating magnetic fields in a broad frequency band, from hertz to tens kilohertz. We illustrate its flexibility and robustness by conducting the rheological studies of simple and polymeric fluids at the nano and microscale. First we reproduce a temperature-dependent viscosity of a synthetic oil used as a viscosity standard. Magnetic rotational spectroscopy with suspended nickel nanorods was used in these studies. As a second example, we converted the magnetic rotator into a pump with precise controlled flow modulation. Using multiwalled carbon nanotubes, we were able to estimate the shear modulus of sickle hemoglobin polymer. We believe that this multifunctional magnetic system will be useful not only for micro and nanorheological studies, but it will find much broader applications requiring remote controlled manipulation of micro and nanoobjects.

  16. Multifunctional hydrogel nano-probes for atomic force microscopy.

    PubMed

    Lee, Jae Seol; Song, Jungki; Kim, Seong Oh; Kim, Seokbeom; Lee, Wooju; Jackman, Joshua A; Kim, Dongchoul; Cho, Nam-Joon; Lee, Jungchul

    2016-01-01

    Since the invention of the atomic force microscope (AFM) three decades ago, there have been numerous advances in its measurement capabilities. Curiously, throughout these developments, the fundamental nature of the force-sensing probe-the key actuating element-has remained largely unchanged. It is produced by long-established microfabrication etching strategies and typically composed of silicon-based materials. Here, we report a new class of photopolymerizable hydrogel nano-probes that are produced by bottom-up fabrication with compressible replica moulding. The hydrogel probes demonstrate excellent capabilities for AFM imaging and force measurement applications while enabling programmable, multifunctional capabilities based on compositionally adjustable mechanical properties and facile encapsulation of various nanomaterials. Taken together, the simple, fast and affordable manufacturing route and multifunctional capabilities of hydrogel AFM nano-probes highlight the potential of soft matter mechanical transducers in nanotechnology applications. The fabrication scheme can also be readily utilized to prepare hydrogel cantilevers, including in parallel arrays, for nanomechanical sensor devices. PMID:27199165

  17. Poly(3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications.

    PubMed

    Misra, Superb K; Ansari, Tahera I; Valappil, Sabeel P; Mohn, Dirk; Philip, Sheryl E; Stark, Wendelin J; Roy, Ipsita; Knowles, Jonathan C; Salih, Vehid; Boccaccini, Aldo R

    2010-04-01

    Poly(3-hydroxybutyrate) (P(3HB)) foams exhibiting highly interconnected porosity (85% porosity) were prepared using a unique combination of solvent casting and particulate leaching techniques by employing commercially available sugar cubes as porogen. Bioactive glass (BG) particles of 45S5 Bioglass grade were introduced in the scaffold microstructure, both in micrometer ((m-BG), <5 microm) and nanometer ((n-BG), 30 nm) sizes. The in vitro bioactivity of the P(3HB)/BG foams was confirmed within 10 days of immersion in simulated body fluid and the foams showed high level of protein adsorption. The foams interconnected porous microstructure proved to be suitable for MG-63 osteoblast cell attachment and proliferation. The foams implanted in rats as subcutaneous implants resulted in a non-toxic and foreign body response after one week of implantation. In addition to showing bioactivity and biocompatibility, the P(3HB)/BG composite foams also exhibited bactericidal properties, which was tested on the growth of Staphylococcus aureus. An attempt was made at developing multifunctional scaffolds by incorporating, in addition to BG, selected concentrations of Vitamin E or/and carbon nanotubes. P(3HB) scaffolds with multifunctionalities (viz. bactericidal, bioactive, electrically conductive, antioxidative behaviour) were thus produced, which paves the way for next generation of advanced scaffolds for bone tissue engineering. PMID:20045554

  18. Multifunctional Magnetic-fluorescent Nanocomposites for Biomedical Applications

    PubMed Central

    2008-01-01

    Nanotechnology is a fast-growing area, involving the fabrication and use of nano-sized materials and devices. Various nanocomposite materials play a number of important roles in modern science and technology. Magnetic and fluorescent inorganic nanoparticles are of particular importance due to their broad range of potential applications. It is expected that the combination of magnetic and fluorescent properties in one nanocomposite would enable the engineering of unique multifunctional nanoscale devices, which could be manipulated using external magnetic fields. The aim of this review is to present an overview of bimodal “two-in-one” magnetic-fluorescent nanocomposite materials which combine both magnetic and fluorescent properties in one entity, in particular those with potential applications in biotechnology and nanomedicine. There is a great necessity for the development of these multifunctional nanocomposites, but there are some difficulties and challenges to overcome in their fabrication such as quenching of the fluorescent entity by the magnetic core. Fluorescent-magnetic nanocomposites include a variety of materials including silica-based, dye-functionalised magnetic nanoparticles and quantum dots-magnetic nanoparticle composites. The classification and main synthesis strategies, along with approaches for the fabrication of fluorescent-magnetic nanocomposites, are considered. The current and potential biomedical uses, including biological imaging, cell tracking, magnetic bioseparation, nanomedicine and bio- and chemo-sensoring, of magnetic-fluorescent nanocomposites are also discussed.

  19. Soil biodiversity and soil community composition determine ecosystem multifunctionality.

    PubMed

    Wagg, Cameron; Bender, S Franz; Widmer, Franco; van der Heijden, Marcel G A

    2014-04-01

    Biodiversity loss has become a global concern as evidence accumulates that it will negatively affect ecosystem services on which society depends. So far, most studies have focused on the ecological consequences of above-ground biodiversity loss; yet a large part of Earth's biodiversity is literally hidden below ground. Whether reductions of biodiversity in soil communities below ground have consequences for the overall performance of an ecosystem remains unresolved. It is important to investigate this in view of recent observations that soil biodiversity is declining and that soil communities are changing upon land use intensification. We established soil communities differing in composition and diversity and tested their impact on eight ecosystem functions in model grassland communities. We show that soil biodiversity loss and simplification of soil community composition impair multiple ecosystem functions, including plant diversity, decomposition, nutrient retention, and nutrient cycling. The average response of all measured ecosystem functions (ecosystem multifunctionality) exhibited a strong positive linear relationship to indicators of soil biodiversity, suggesting that soil community composition is a key factor in regulating ecosystem functioning. Our results indicate that changes in soil communities and the loss of soil biodiversity threaten ecosystem multifunctionality and sustainability. PMID:24639507

  20. Multifunctional magnetic rotator for micro and nanorheological studies.

    PubMed

    Tokarev, Alexander; Aprelev, Alexey; Zakharov, Mikhail N; Korneva, Guzeliya; Gogotsi, Yury; Kornev, Konstantin G

    2012-06-01

    We report on the development of a multifunctional magnetic rotator that has been built and used during the last five years by two groups from Clemson and Drexel Universities studying the rheological properties of microdroplets. This magnetic rotator allows one to generate rotating magnetic fields in a broad frequency band, from hertz to tens kilohertz. We illustrate its flexibility and robustness by conducting the rheological studies of simple and polymeric fluids at the nano and microscale. First we reproduce a temperature-dependent viscosity of a synthetic oil used as a viscosity standard. Magnetic rotational spectroscopy with suspended nickel nanorods was used in these studies. As a second example, we converted the magnetic rotator into a pump with precise controlled flow modulation. Using multiwalled carbon nanotubes, we were able to estimate the shear modulus of sickle hemoglobin polymer. We believe that this multifunctional magnetic system will be useful not only for micro and nanorheological studies, but it will find much broader applications requiring remote controlled manipulation of micro and nanoobjects. PMID:22755665

  1. Multifunctional receptor-targeting antibodies for cancer therapy.

    PubMed

    Zhu, Yanni; Choi, Sung Hugh; Shah, Khalid

    2015-11-01

    During the past decade, monospecific antibodies targeting cell-surface receptors in different tumour types have achieved substantial success and have been at the forefront of cancer treatment. However, redundant signalling and crosstalk between different pathways within tumour cells and between tumour cells and their microenvironment can limit the efficacy of receptor-targeted monospecific-based therapies. Advances in antibody engineering technologies have enabled strategies that simultaneously target multiple receptors to circumvent the limitations of conventional monospecific therapies and achieve enhanced therapeutic efficacy. In the past 5 years, a range of multifunctional, receptor-targeting, antibody-based molecules have emerged, which allow targeting of multiple surface receptors on tumour cells and endothelial or immune cells in the tumour microenvironment. In this Review, we discuss the rationales and strategies for the use of multifunctional receptor-targeting antibodies, their mechanisms of action, and the promises and challenges they hold as cancer therapeutics. This knowledge provides opportunities to improve current targeted therapy outcomes for patients with cancer. PMID:26545843

  2. MICRO-CHP System for Residential Applications

    SciTech Connect

    Joseph Gerstmann

    2009-01-31

    This is the final report of progress under Phase I of a project to develop and commercialize a micro-CHP system for residential applications that provides electrical power, heating, and cooling for the home. This is the first phase of a three-phase effort in which the residential micro-CHP system will be designed (Phase I), developed and tested in the laboratory (Phase II); and further developed and field tested (Phase III). The project team consists of Advanced Mechanical Technology, Inc. (AMTI), responsible for system design and integration; Marathon Engine Systems, Inc. (MES), responsible for design of the engine-generator subsystem; AO Smith, responsible for design of the thermal storage and water heating subsystems; Trane, a business of American Standard Companies, responsible for design of the HVAC subsystem; and AirXchange, Inc., responsible for design of the mechanical ventilation and dehumidification subsystem.

  3. Housing supply and residential segregation in Ireland.

    PubMed

    Vang, Zoua M

    2010-01-01

    The article examines the role of housing supply in ethnic diversity and the residential segregation of Asian, African and eastern European immigrants from Irish nationals in Ireland. Housing supply is defined as the proportions of new housing, private rental accommodation and social housing among all housing units in an electoral district. Multivariate regressions reveal that, among all three housing supply variables, the proportion of private rentals had the largest effect on ethnic diversity and immigrant— Irish segregation. Areas with higher proportions of private rental units were more ethnically diverse, had greater presences of Africans, Asians and eastern Europeans (as opposed to high concentrations of Irish nationals) and exhibited greater integration between each of the three immigrant groups and Irish nationals. The article concludes with a discussion of immigrant assimilation and questions whether the patterns of residential integration observed would further facilitate other forms of social inclusion for immigrants in Irish society. PMID:21114091

  4. Panethnicity, Ethnic Diversity and Residential Segregation

    PubMed Central

    Kim, Ann H.; White, Michael J.

    2013-01-01

    We consider the theoretical and empirical implications of the structural basis of panethnicity and of the layering of ethnic boundaries in residential patterns while simultaneously evaluating the ‘panethnic hypothesis’, that is, the extent to which homogeneity within panethnic categories can be assumed. Our results do show a panethnic effect – greater residential proximity is evident within panethnic boundaries than between, net of ethnic group size and metropolitan area, but this association clearly depends on immigration. While findings generally show a lower degree of social distance between panethnic subgroups, particularly for blacks, whites and Latinos and less for Asians, ethno-national groups continue to maintain some degree of distinctiveness within a racialized context. PMID:20503650

  5. Residential air conditioner cycling: A case study

    SciTech Connect

    Strickler, G.F.; Noell, S.K.

    1988-02-01

    Southern California Edison currently operates its Residential Air Conditioner Cycling Program as a production program on a systemwide basis. Air conditioner cycling enables Edison to cycle, or switch off, at predetermined intervals, approximately 100,000 air conditioners throughout the Edison service areas. Activation of this system reduces peak demands for load shaping capability. Benefits of this method of peak reduction include the potential for system load factor improvement and/or for deferral of construction of new generation facilities. Edison began testing hardware for direct load control in 1976. Experimental test programs were implemented from 1978 through 1980. These successful test programs resulted in the decision to implement the Residential Air Conditioner Cycling Program on a systemwide basis in 1983.

  6. METHODOLOGICAL ISSUES IN THE ANALYSIS OF RESIDENTIAL PREFERENCES, RESIDENTIAL MOBILITY, AND NEIGHBORHOOD CHANGE1

    PubMed Central

    Bruch, Elizabeth E.; Mare, Robert D.

    2011-01-01

    This paper reviews methods for analyzing both individual preferences and choices about where to live, and the implications of these choices for residential patterns. Although these methods are discussed in the context of residential choice, they can be applied more broadly to individual choices in a range of social contexts where behavior is interdependent. We review a variety of types of data on residential preferences and mobility and discuss appropriate statistical models for these data. We discuss the analysis of ranked and other types of clustered data; functional form issues; problems of unobserved heterogeneity in individuals and in neighborhoods; and strengths and weaknesses of stated preference data versus observations of actual mobility behavior. We also discuss specific problems with residential mobility data, including the treatment of one’s current location as a potential choice, how to specify the choice set of potential movers, the aggregation of units (such as dwelling units into neighborhoods) and the need to take account of variations in neighborhood size, the problem of very large choice sets and possible sampling solutions; and the link between residential mobility and patterns of neighborhood change. PMID:23476098

  7. Residential photovoltaic power systems for the northeast

    SciTech Connect

    Russell, M. C.

    1981-01-01

    A project to develop Residential Photovoltaic Systems has begun at Massachusetts Institute of Technology Lincoln Laboratory with the construction and testing of five Prototype Systems. Each of these systems utilizes a roof-mounted photovoltaic array and allows excess solar-generated electric energy to be fed back to the local utility grid, eliminating the need for on-site storage. Specific features of the five Prototype Systems now under test are presented, and performance results to date are discussed.

  8. Songs for Residential Outdoor Education Programs.

    ERIC Educational Resources Information Center

    Wood, Diane, Comp.

    A collection of songs for residential outdoor education programs gives the lyrics to 42 recent and traditonal songs. Recent songs include "Leaving on a Jet Plane,""Blowin' in the Wind,""Country Roads,""Last Thing on My Mind,""City of New Orleans,""Me and Bobby McGee,""Moon River," and "I Shall be Released." Modern folk songs included are "Jamaica…

  9. Predicting elopement from residential treatment centers.

    PubMed

    Kashubeck, S; Pottebaum, S M; Read, N O

    1994-01-01

    To identify predictors of elopement in young patients in residential treatment, runaways were compared with a matched sample of nonrunaways. Runaways were more likely to have a history of elopement, a suspected history of sexual abuse, an affective disorder diagnosis, and parents whose rights had been terminated. The results suggested that the likelihood of elopement can be accurately predicted on the basis of patient characteristics known at admission. PMID:8147421

  10. Sudden Infant Death Syndrome and Residential Altitude

    PubMed Central

    Shore, Supriya; Bandle, Brian; Niermeyer, Susan; Bol, Kirk A.; Khanna, Amber

    2015-01-01

    BACKGROUND: Theories of sudden infant death syndrome (SIDS) suggest hypoxia is a common pathway. Infants living at altitude have evidence of hypoxia; however, the association between SIDS incidence and infant residential altitude has not been well studied. METHODS: We performed a retrospective cohort study by using data from the Colorado birth and death registries from 2007 to 2012. Infant residential altitude was determined by geocoding maternal residential address. Logistic regression was used to determine adjusted association between residential altitude and SIDS. We evaluated the impact of the Back to Sleep campaign across various altitudes in an extended cohort from 1990 to 2012 to assess for interaction between sleep position and altitude. RESULTS: A total of 393 216 infants born between 2007 and 2012 were included in the primary cohort (51.4% boys; mean birth weight 3194 ± 558 g). Overall, 79.6% infants resided at altitude <6000 feet, 18.5% at 6000 to 8000 feet, and 1.9% at >8000 feet. There were no meaningful differences in maternal characteristics across altitude groups. Compared with residence <6000 feet, residence at high altitude (>8000 feet), was associated with an adjusted increased risk of SIDS (odds ratio 2.30; 95% confidence interval 1.01–5.24). Before the Back to Sleep campaign, the incidence of SIDS in Colorado was 1.99/1000 live births and dropped to 0.57/1000 live births after its implementation. The Back to Sleep campaign had similar effect across different altitudes (P = .45). CONCLUSIONS: Residence at high altitude was significantly associated with an increased adjusted risk for SIDS. Impact of the Back to Sleep campaign was similar across various altitudes. PMID:26009621

  11. Development of a Variable-Speed Residential Air-Source Integrated Heat Pump

    SciTech Connect

    Rice, C Keith; Shen, Bo; Munk, Jeffrey D; Ally, Moonis Raza; Baxter, Van D

    2014-01-01

    A residential air-source integrated heat pump (AS-IHP) is under development in partnership with a U.S. manufacturer. A nominal 10.6 kW (3-ton) cooling capacity variable-speed unit, the system provides both space conditioning and water heating. This multi-functional unit can provide domestic water heating (DWH) in either full condensing (FC) (dedicated water heating or simultaneous space cooling and water heating) or desuperheating (DS) operation modes. Laboratory test data were used to calibrate a vapor-compression simulation model for each mode of operation. The model was used to optimize the internal control options for efficiency while maintaining acceptable comfort conditions and refrigerant-side pressures and temperatures within allowable operating envelopes. Annual simulations were performed with the AS-IHP installed in a well-insulated house in five U.S. climate zones. The AS-IHP is predicted to use 45 to 60% less energy than a DOE minimum efficiency baseline system while meeting total annual space conditioning and water heating loads. Water heating energy use is lowered by 60 to 75% in cold to warmer climates, respectively. Plans are to field test the unit in Knoxville, TN.

  12. Evaluation of evolving residential electricity tariffs

    SciTech Connect

    Lai, Judy; DeForest, Nicholas; Kiliccote, Sila; Stadler, Michael; Marnay, Chris; Donadee, Jon

    2011-03-22

    Residential customers in California's Pacific Gas and Electric (PG&E) territory have seen several electricity rate structure changes in the past decade. A relatively simple two-tiered pricing system (charges by usage under/over baseline for the home's climate zone) was replaced in the summer of 2001 by a more complicated five-tiered system (usage below baseline and up to 30percent, 100percent, 200percent, and 300percent+ over baseline). In 2009, PG&E began the process of upgrading its residential customers to Smart Meters and laying the groundwork for time of use pricing, due to start in 2011. This paper examines the history of the tiered pricing system, discusses the problems the utility encountered with its Smart Meter roll out, and evaluates the proposed dynamic pricing incentive structures. Scenario analyses of example PG&E customer bills will also be presented. What would these residential customers pay if they were still operating under a tiered structure, and/or if they participated in peak hour reductions?

  13. Residential building code compliance: Implications for evaluating the performance of utility residential new construction programs

    SciTech Connect

    Vine, E.

    1996-05-01

    Knowing how well builders comply with (or exceed) energy-related building codes is critical for completing a sound evaluation of utility residential new construction programs and for determining the actual cost-effectiveness of these programs. Obtaining credit from utility regulators for additional energy savings from code compliance in participant houses as a result of the utility program is one of the key options available for utilities for improving the cost-effectiveness of these programs. In this paper, the authors examine residential building energy code compliance and specific code violations in three states (California, Oregon and Washington). They then compare residential building energy code compliance for program participants and nonparticipants as well as estimates of the energy savings impacts from noncompliance. The authors also point out some of the methodological limitations of these studies which limit the ability to generalize from these studies.

  14. Residential solar photovoltaic systems: Final report for the Northeast Residential Experiment Station

    SciTech Connect

    Kern, E.C. Jr.

    1986-06-01

    This report covers research and development work conducted by the MIT Energy Lab. from July 1982 through June 1986. This Energy Lab. work in the field of solar photovoltaic systems followed six years of similar work at the MIT Lincoln Lab. under the same contract with the US DOE. The final report from the Lincoln Lab. period was published by Lincoln Lab. in 1983. During the period of Energy Lab. involvement, the project focused on the refinement of residential scale, roof-mounted photovoltaic systems for application in the northeastern US. Concurrent with the conclusion of MIT`s involvement, the New England Electric Co. is building a major field test of residential photovoltaics in Gardner, Massachusetts to determine experimentally the effects of photovoltaics on electric power company operations. Using systems designs and technology developed at MIT, the long-term performance of these thirty residential systems in Gardner will provide a measure of our success.

  15. An Assessment of the U.S. Residential Lighting Market

    SciTech Connect

    Jennings, Judy; Brown, Rich; Moezzi, Mithra; Mills, Evan; Sardinsky, Robert

    1995-10-01

    This report provides background data upon which residential lighting fixture energy conservation programs can be built. The current stock of residential lighting is described by usage level, lamp wattage, fixture type, and location within the house. Data are discussed that indicate that 25% of residential fixtures are responsible for 80% of residential lighting energy use, and that justify targeting these fixtures as candidates for retrofit with energy-efficient fixtures. Fixtures determined to have the highest energy use are hardwired ceiling fixtures in kitchens, living/family rooms, dining rooms, and outdoors. An assessment of the market for residential fixtures shows that nearly half of new residential fixtures are imported, 61% of new fixtures sold are hardwired, and about half of all new fixtures sold are for ceiling installation.

  16. Market and economic analysis of residential photovoltaic systems

    NASA Astrophysics Data System (ADS)

    Tabors, R. D.

    1982-06-01

    The overall structure of a project to evaluate the U.S. residential photovoltaic market or markets is reviewed and experience obtained before cuts in federal funding for the project were reduced is summarized. Topics covered include residential worth analysis, (including retrofit applications); evaluation of presently available regional, econometric models which could be used to project housing stocks; and the analysis of retrofit potential for residential photovoltaic power systems given available roof area.

  17. The drivers to adopt renewable energy among residential users.

    NASA Astrophysics Data System (ADS)

    Rahman, Zahari Abdul; Elinda, Esa

    2016-03-01

    This study aims to examine the drivers to adopt renewable energy (RE) among residential users in Malaysia. Based on the theoretical framework of a consumer’s decision making process, an empirical study of the adoption of RE was conducted. A total of 501 residential users were used in this study. This study proved that perceived utility of new technology, perceived utility of new service, and perceived benefit of new technology are the drivers to adopt RE among residential users. These factors are knowing crucial to RE suppliers and producers because it will generates more demand from the residential users and the percentage of energy mix from RE sources can be increase.

  18. Enact legislation supporting residential property assessed clean energy financing (PACE)

    SciTech Connect

    Saha, Devashree

    2012-11-15

    Congress should enact legislation that supports residential property assessed clean energy (PACE) programs in the nation’s states and metropolitan areas. Such legislation should require the Federal Housing Finance Agency (FHFA) to allow Fannie Mae and Freddie Mac to purchase residential mortgages with PACE assessments while at the same time providing responsible underwriting standards and a set of benchmarks for residential PACE assessments in order to minimize financial risks to mortgage holders. Congressional support of residential PACE financing will improve energy efficiency, encourage job creation, and foster economic growth in the nation’s state and metropolitan areas.

  19. Hyperhemispheric multifunction sensors for ground combat vehicles: concept evaluation using virtual prototyping

    NASA Astrophysics Data System (ADS)

    Krapels, Keith; Preece, Brad; Furxhi, Orges; Driggers, Ronald

    2016-05-01

    As the defense budget reduces and we are asked to do more with less (seems to have been a major theme now for over 10 years), multifunction systems are becoming critical to the future of military EOIR systems. The design of multifunction (MF) sensors is not a well-developed or well-understood discipline. In this paper, we provide an example trade study of a ground combat system hyperhemispheric multifunction system. In addition, we show how concept evaluation can be achieved using a virtual prototyping environment.

  20. Strong, light, multifunctional fibers of carbon nanotubes with ultrahigh conductivity.

    PubMed

    Behabtu, Natnael; Young, Colin C; Tsentalovich, Dmitri E; Kleinerman, Olga; Wang, Xuan; Ma, Anson W K; Bengio, E Amram; ter Waarbeek, Ron F; de Jong, Jorrit J; Hoogerwerf, Ron E; Fairchild, Steven B; Ferguson, John B; Maruyama, Benji; Kono, Junichiro; Talmon, Yeshayahu; Cohen, Yachin; Otto, Marcin J; Pasquali, Matteo

    2013-01-11

    Broader applications of carbon nanotubes to real-world problems have largely gone unfulfilled because of difficult material synthesis and laborious processing. We report high-performance multifunctional carbon nanotube (CNT) fibers that combine the specific strength, stiffness, and thermal conductivity of carbon fibers with the specific electrical conductivity of metals. These fibers consist of bulk-grown CNTs and are produced by high-throughput wet spinning, the same process used to produce high-performance industrial fibers. These scalable CNT fibers are positioned for high-value applications, such as aerospace electronics and field emission, and can evolve into engineered materials with broad long-term impact, from consumer electronics to long-range power transmission. PMID:23307737

  1. Multi-Scale Sizing of Lightweight Multifunctional Spacecraft Structural Components

    NASA Technical Reports Server (NTRS)

    Bednarcyk, Brett A.

    2005-01-01

    This document is the final report for the project entitled, "Multi-Scale Sizing of Lightweight Multifunctional Spacecraft Structural Components," funded under the NRA entitled "Cross-Enterprise Technology Development Program" issued by the NASA Office of Space Science in 2000. The project was funded in 2001, and spanned a four year period from March, 2001 to February, 2005. Through enhancements to and synthesis of unique, state of the art structural mechanics and micromechanics analysis software, a new multi-scale tool has been developed that enables design, analysis, and sizing of advance lightweight composite and smart materials and structures from the full vehicle, to the stiffened structure, to the micro (fiber and matrix) scales. The new software tool has broad, cross-cutting value to current and future NASA missions that will rely on advanced composite and smart materials and structures.

  2. Study of repeater technology for advanced multifunctional communications satellites

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Investigations are presented concerning design concepts and implementation approaches for the satellite communication repeater subsystems of advanced multifunctional satellites. In such systems the important concepts are the use of multiple antenna beams, repeater switching (routing), and efficient spectrum utilization through frequency reuse. An information base on these techniques was developed and tradeoff analyses were made of repeater design concepts, with the work design taken in a broad sense to include modulation beam coverage patterns. There were five major areas of study: requirements analysis and processing; study of interbeam interference in multibeam systems; characterization of multiple-beam switching repeaters; estimation of repeater weight and power for a number of alternatives; and tradeoff analyses based on these weight and power data.

  3. Complex metal borohydrides: multifunctional materials for energy storage and conversion.

    PubMed

    Mohtadi, Rana; Remhof, Arndt; Jena, Puru

    2016-09-01

    With the limited supply of fossil fuels and their adverse effect on the climate and the environment, it has become a global priority to seek alternate sources of energy that are clean, abundant, and sustainable. While sources such as solar, wind, and hydrogen can meet the world's energy demand, considerable challenges remain to find materials that can store and/or convert energy efficiently. This topical review focuses on one such class of materials, namely, multi-functional complex metal borohydrides that not only have the ability to store sufficient amount of hydrogen to meet the needs of the transportation industry, but also can be used for a new generation of metal ion batteries and solar cells. We discuss the material challenges in all these areas and review the progress that has been made to address them, the issues that still need to be resolved and the outlook for the future. PMID:27384871

  4. Large Format Multifunction 2-Terabyte Optical Disk Storage System

    NASA Technical Reports Server (NTRS)

    Kaiser, David R.; Brucker, Charles F.; Gage, Edward C.; Hatwar, T. K.; Simmons, George O.

    1996-01-01

    The Kodak Digital Science OD System 2000E automated disk library (ADL) base module and write-once drive are being developed as the next generation commercial product to the currently available System 2000 ADL. Under government sponsorship with the Air Force's Rome Laboratory, Kodak is developing magneto-optic (M-O) subsystems compatible with the Kodak Digital Science ODW25 drive architecture, which will result in a multifunction (MF) drive capable of reading and writing 25 gigabyte (GB) WORM media and 15 GB erasable media. In an OD system 2000 E ADL configuration with 4 MF drives and 100 total disks with a 50% ration of WORM and M-O media, 2.0 terabytes (TB) of versatile near line mass storage is available.

  5. Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites

    PubMed Central

    Khlebtsov, Nikolai; Bogatyrev, Vladimir; Dykman, Lev; Khlebtsov, Boris; Staroverov, Sergey; Shirokov, Alexander; Matora, Larisa; Khanadeev, Vitaly; Pylaev, Timofey; Tsyganova, Natalia; Terentyuk, Georgy

    2013-01-01

    Gold nanoparticles (GNPs) and GNP-based multifunctional nanocomposites are the subject of intensive studies and biomedical applications. This minireview summarizes our recent efforts in analytical and theranostic applications of engineered GNPs and nanocomposites by using plasmonic properties of GNPs and various optical techniques. Specifically, we consider analytical biosensing; visualization and bioimaging of bacterial, mammalian, and plant cells; photodynamic treatment of pathogenic bacteria; and photothermal therapy of xenografted tumors. In addition to recently published reports, we discuss new data on dot immunoassay diagnostics of mycobacteria, multiplexed immunoelectron microscopy analysis of Azospirillum brasilense, materno-embryonic transfer of GNPs in pregnant rats, and combined photodynamic and photothermal treatment of rat xenografted tumors with gold nanorods covered by a mesoporous silica shell doped with hematoporphyrin. PMID:23471188

  6. Multifunctional nanoparticle systems for combined chemoand photothermal cancer therapy

    NASA Astrophysics Data System (ADS)

    Wang, Hai; Zhao, Yu-Liang; Nie, Guang-Jun

    2013-06-01

    Hyperthermia has long been considered as an adjuvant therapy for treating various diseases. Cancer treatment exploiting hyperthermia shows great clinical potential for a wide range of tumors. Importantly, the efficacy of hyperthermal therapy has recently been enhanced by the development of functional nanomaterials. The unique physicochemical properties of nanomaterials afford the specific localization of hyperthermia to primary tumors and early-stage cancers. In particular, due to their high rate of light-to-heat conversion and their capacity to be activated by tissue-penetrating electromagnetic radiation, near-infrared (NIR) light-absorbing plasmonic nanomaterials have attracted considerable attention as candidates for noninvasive photothermal therapy. The purpose of this article is to provide a overview on the current development in multifunctional nanomaterials capable of combined hyperthermia-chemotherapy delivery.

  7. Functional and multifunctional polymers: Materials for smart structures

    SciTech Connect

    Arnold, S.; Li, J.; Pratt, L.; Khan, I.M.

    1995-12-01

    A number of functional and multifunctional polymeric systems with potential applications in smart structures will be discussed. The synthesis, characterization and some applications of the microphase separated mixed (electronic and ionic) conductive or MIEC block copolymers will be presented. One such series is poly[3-methylthiophene-co-3-octylthiophene)-block-{omega}-methoxyocta(oxyethylene) methacrylate] block copolymers. Applications of these polymers are in synthetic muscles, electromagnetic shielding materials, membranes for biological electron transfer processes. A new class of proccessible and electroactive polymers, copolymers of (3-methyl or 3-phenyl)thiophene and (3-oligodimethy)siloxane)thiophene will be reported. These polymers have applications in electrorheological fluids and synthetic muscles. Also, a easier methodology for preparing highly ionic conductive and elastomeric solid polymer electrolytes by blending commercial polymers will be discussed. Application of these materials are in electrochromic windows and solid state microelectromechanical devices.

  8. Macro- and microphase separation in multifunctional supramolecular polymer networks

    NASA Astrophysics Data System (ADS)

    Mester, Zoltan; Mohan, Aruna; Fredrickson, Glenn

    2011-03-01

    We develop a field-based model for a binary melt of multifunctional polymers that can reversibly bond to form copolymer networks. The mean-field phase separation behavior of several model networks with heterogeneous bonding is calculated via the random phase approximation (RPA). The extent of bonding between polymers is controlled by specified bond energies. The phase boundary calculated via RPA is the stability limit of the homogeneous disordered phase to coexisting homogeneous macrophases, for low bond strengths, and to microphases, for high bond strengths. An isotropic Lifshitz point separates these two regions along the spindodal boundary. It is demonstrated that higher functionality and higher bond strength suppresses macrophase separation due to greater connectivity between unlike species. Gelation first occurs at a bond strength higher than the Lifshitz point for tri- or higher functional polymer components.

  9. Hydrogen-Bonded Multifunctional Supramolecular Copolymers in Water.

    PubMed

    Xiang, Yunjie; Moulin, Emilie; Buhler, Eric; Maaloum, Mounir; Fuks, Gad; Giuseppone, Nicolas

    2015-07-21

    We have investigated the self-assembly in water of molecules having a single hydrophobic bis-urea domain linked to different hydrophilic functional side chains, i.e., bioactive peptidic residues and fluorescent cyanine dyes. By using a combination of spectroscopy, scattering, and microscopy techniques, we show that each one of these molecules can individually produce well-defined nanostructures such as twisted ribbons, two-dimensional plates, or branched fibers. Interestingly, when these monomers of different functionalities are mixed in an equimolar ratio, supramolecular copolymers are preferred to narcissistic segregation. Radiation scattering and imaging techniques demonstrate that one of the molecular units dictates the formation of a preferential nanostructure, and optical spectroscopies reveal the alternated nature of the copolymerization process. This work illustrates how social self-sorting in H-bond supramolecular polymers can give straightforward access to multifunctional supramolecular copolymers. PMID:26087392

  10. Multi-functionality and plasticity characterize epithelial cells in Hydra

    PubMed Central

    Buzgariu, W; Al Haddad, S; Tomczyk, S; Wenger, Y; Galliot, B

    2015-01-01

    Epithelial sheets, a synapomorphy of all metazoans but porifers, are present as 2 layers in cnidarians, ectoderm and endoderm, joined at their basal side by an extra-cellular matrix named mesoglea. In the Hydra polyp, epithelial cells of the body column are unipotent stem cells that continuously self-renew and concomitantly express their epitheliomuscular features. These multifunctional contractile cells maintain homeostasis by providing a protective physical barrier, by digesting nutrients, by selecting a stable microbiota, and by rapidly closing wounds. In addition, epithelial cells are highly plastic, supporting the adaptation of Hydra to physiological and environmental changes, such as long starvation periods where survival relies on a highly dynamic autophagy flux. Epithelial cells also play key roles in developmental processes as evidenced by the organizer activity they develop to promote budding and regeneration. We propose here an integrative view of the homeostatic and developmental aspects of epithelial plasticity in Hydra. PMID:26716072

  11. Nucleolin: The most abundant multifunctional phosphoprotein of nucleolus.

    PubMed

    Tajrishi, Marjan M; Tuteja, Renu; Tuteja, Narendra

    2011-05-01

    Nucleolin is a multifunctional phosphoprotein ubiquitously distributed in the nucleolus, nucleus and cytoplasm of the cell. Nucleolin has a bipartite nuclear localization signal sequence and is conserved in animals, plants and yeast. Its levels are correlated with the rate of functional activity of the nucleolus in exponentially growing cells. Nucleolin contains intrinsic DNA and RNA helicase, nucleic-acid-dependent ATPase and self-cleaving activities. It binds RNA through its RNA recognition motifs. It regulates various aspects of DNA and RNA metabolism, chromatin structure, rDNA transcription, rRNA maturation, cytokinesis, nucleogenesis, cell proliferation and growth, the folding, maturation and ribosome assembly and nucleocytoplasmic transport of newly synthesized pre-RNAs. In this review we present an overview on nucleolin, its localization, structure and various functions. We also describe the discovery and important studies of nucleolin in plants. PMID:21980556

  12. Multifunctional, flexible electronic systems based on engineered nanostructured materials

    NASA Astrophysics Data System (ADS)

    Ko, Hyunhyub; Kapadia, Rehan; Takei, Kuniharu; Takahashi, Toshitake; Zhang, Xiaobo; Javey, Ali

    2012-08-01

    The development of flexible electronic systems has been extensively researched in recent years, with the goal of expanding the potential scope and market of modern electronic devices in the areas of computation, communications, displays, sensing and energy. Uniquely, the use of soft polymeric substrates enables the incorporation of advanced features beyond mechanical bendability and stretchability. In this paper, we describe several functionalities which can be achieved using engineered nanostructured materials. In particular, reversible binding, self-cleaning, antireflective and shape-reconfigurable properties are introduced for the realization of multifunctional, flexible electronic devices. Examples of flexible systems capable of spatial mapping and/or responding to external stimuli are also presented as a new class of user-interactive devices.

  13. Multifunctionality of chiton biomineralized armor with an integrated visual system.

    PubMed

    Li, Ling; Connors, Matthew J; Kolle, Mathias; England, Grant T; Speiser, Daniel I; Xiao, Xianghui; Aizenberg, Joanna; Ortiz, Christine

    2015-11-20

    Nature provides a multitude of examples of multifunctional structural materials in which trade-offs are imposed by conflicting functional requirements. One such example is the biomineralized armor of the chiton Acanthopleura granulata, which incorporates an integrated sensory system that includes hundreds of eyes with aragonite-based lenses. We use optical experiments to demonstrate that these microscopic lenses are able to form images. Light scattering by the polycrystalline lenses is minimized by the use of relatively large, crystallographically aligned grains. Multiscale mechanical testing reveals that as the size, complexity, and functionality of the integrated sensory elements increase, the local mechanical performance of the armor decreases. However, A. granulata has evolved several strategies to compensate for its mechanical vulnerabilities to form a multipurpose system with co-optimized optical and structural functions. PMID:26586760

  14. Internet-based calibration of a multifunction calibrator

    SciTech Connect

    BUNTING BACA,LISA A.; DUDA JR.,LEONARD E.; WALKER,RUSSELL M.; OLDHAM,NILE; PARKER,MARK

    2000-04-17

    A new way of providing calibration services is evolving which employs the Internet to expand present capabilities and make the calibration process more interactive. Sandia National Laboratories and the National Institute of Standards and Technology are collaborating to set up and demonstrate a remote calibration of multifunction calibrators using this Internet-based technique that is becoming known as e-calibration. This paper describes the measurement philosophy and the Internet resources that can provide real-time audio/video/data exchange, consultation and training, as well as web-accessible test procedures, software and calibration reports. The communication system utilizes commercial hardware and software that should be easy to integrate into most calibration laboratories.

  15. The multifunctional SNM1 gene family: not just nucleases

    PubMed Central

    Yan, Yiyi; Akhter, Shamima; Zhang, Xiaoshan; Legerski, Randy

    2010-01-01

    The archetypical member of the SNM1 gene family was discovered 30 years ago in the budding yeast Saccharomyces cerevisiae. This small but ubiquitous gene family is characterized by metallo-β-lactamase and β-CASP domains, which together have been demonstrated to comprise a nuclease activity. Three mammalian members of this family, SNM1A, SNM1B/Apollo and Artemis, have been demonstrated to play surprisingly divergent roles in cellular metabolism. These pathways include variable (diversity) joining recombination, nonhomologous end-joining of double-strand breaks, DNA damage and mitotic cell cycle checkpoints, telomere maintenance and protein ubiquitination. Not all of these functions are consistent with a model in which these proteins act only as nucleases, and indicate that the SNM1 gene family encodes multifunctional products that can act in diverse biochemical pathways. In this article we discuss the various functions of SNM1A, SNM1B/Apollo and Artemis. PMID:20528238

  16. Fluorescent ampicillin analogues as multifunctional disguising agents against opsonization

    NASA Astrophysics Data System (ADS)

    Kotagiri, Nalinikanth; Sakon, Joshua; Han, Haewook; Zharov, Vladimir P.; Kim, Jin-Woo

    2016-06-01

    Cancer nanomedicines are opening new paradigms in cancer management and recent research points to how they can vastly improve imaging and therapy through multimodality and multifunctionality. However, challenges to achieving optimal efficacy are manifold starting from processing materials and evaluating their intended effectiveness on biological tissue, to developing new strategies aimed at improving transport of these materials through the biological milieu to the target tissue. Here, we report a fluorescent derivative of a beta-lactam antibiotic, ampicillin (termed iAmp) and its multifunctional physicobiochemical characteristics and potential as a biocompatible shielding agent and an effective dispersant. Carbon nanotubes (CNTs) were chosen to demonstrate the efficacy of iAmp. CNTs are known for their versatility and have been used extensively for cancer theranostics as photothermal and photoacoustic agents, but have limited solubility in water and biocompatibility. Traditional dispersants are associated with imaging artifacts and are not fully biocompatible. The chemical structure of iAmp is consistent with a deamination product of ampicillin. Although the four-membered lactam ring is intact, it does not retain the antibiotic properties. The iAmp is an effective dispersant and simultaneously serves as a fluorescent label for single-walled CNTs (SWNTs) with minimal photobleaching. The iAmp also enables bioconjugation of SWNTs to bio-ligands such as antibodies through functional carboxyl groups. Viability tests show that iAmp-coated SWNTs have minimal toxicity. Bio-stability tests under physiological conditions reveal that iAmp coating not only remains stable in a biologically relevant environment with high protein and salt concentrations, but also renders SWNTs transparent against nonspecific protein adsorption, also known as protein corona. Mammalian tissue culture studies with macrophages and opsonins validate that iAmp coating affords immunological resistance

  17. In vivo minimally invasive interstitial multi-functional microendoscopy

    PubMed Central

    Shahmoon, Asaf; Aharon, Shiran; Kruchik, Oded; Hohmann, Martin; Slovin, Hamutal; Douplik, Alexandre; Zalevsky, Zeev

    2013-01-01

    Developing minimally invasive methodologies for imaging of internal organs is an emerging field in the biomedical examination research. This paper introduces a new multi-functional microendoscope device capable of imaging of internal organs with a minimal invasive intervention. In addition, the developed microendoscope can also be employed as a monitoring device for measuring local hemoglobin concentration in blood stream when administrated into a blood artery. The microendoscope device has a total external diameter of only 200 μm and can provide high imaging resolution capability of more than 5,000 pixels. The device can detect features with a spatial resolution of less than 1 μm. The microendoscope has been tested both in-vitro as well as in-vivo in rats presenting a promising and powerful tool as a high resolution and minimally invasive imaging facility suitable for previously unreachable clinical modalities. PMID:23712369

  18. Multi-functionality and plasticity characterize epithelial cells in Hydra.

    PubMed

    Buzgariu, W; Al Haddad, S; Tomczyk, S; Wenger, Y; Galliot, B

    2015-01-01

    Epithelial sheets, a synapomorphy of all metazoans but porifers, are present as 2 layers in cnidarians, ectoderm and endoderm, joined at their basal side by an extra-cellular matrix named mesoglea. In the Hydra polyp, epithelial cells of the body column are unipotent stem cells that continuously self-renew and concomitantly express their epitheliomuscular features. These multifunctional contractile cells maintain homeostasis by providing a protective physical barrier, by digesting nutrients, by selecting a stable microbiota, and by rapidly closing wounds. In addition, epithelial cells are highly plastic, supporting the adaptation of Hydra to physiological and environmental changes, such as long starvation periods where survival relies on a highly dynamic autophagy flux. Epithelial cells also play key roles in developmental processes as evidenced by the organizer activity they develop to promote budding and regeneration. We propose here an integrative view of the homeostatic and developmental aspects of epithelial plasticity in Hydra. PMID:26716072

  19. Advances in process intensification through multifunctional reactor engineering.

    SciTech Connect

    Cooper, Marcia A.; Miller, James Edward; O'Hern, Timothy John; Gill, Walter; Evans, Lindsey R.

    2011-02-01

    A multifunctional reactor is a chemical engineering device that exploits enhanced heat and mass transfer to promote production of a desired chemical, combining more than one unit operation in a single system. The main component of the reactor system under study here is a vertical column containing packing material through which liquid(s) and gas flow cocurrently downward. Under certain conditions, a range of hydrodynamic regimes can be achieved within the column that can either enhance or inhibit a desired chemical reaction. To study such reactors in a controlled laboratory environment, two experimental facilities were constructed at Sandia National Laboratories. One experiment, referred to as the Two-Phase Experiment, operates with two phases (air and water). The second experiment, referred to as the Three-Phase Experiment, operates with three phases (immiscible organic liquid and aqueous liquid, and nitrogen). This report describes the motivation, design, construction, operational hazards, and operation of the both of these experiments. Data and conclusions are included.

  20. A New Multifunctional Sensor for Measuring Concentrations of Ternary Solution

    NASA Astrophysics Data System (ADS)

    Wei, Guo; Shida, Katsunori

    This paper presents a multifunctional sensor with novel structure, which is capable of directly sensing temperature and two physical parameters of solutions, namely ultrasonic velocity and conductivity. By combined measurement of these three measurable parameters, the concentrations of various components in a ternary solution can be simultaneously determined. The structure and operation principle of the sensor are described, and a regression algorithm based on natural cubic spline interpolation and the least square method is adopted to estimate the concentrations. The performances of the proposed sensor are experimentally tested by the use of ternary aqueous solution of sodium chloride and sucrose, which is widely involved in food and beverage industries. This sensor could prove valuable as a process control sensor in industry fields.

  1. Photonic spin-controlled multifunctional shared-aperture antenna array.

    PubMed

    Maguid, Elhanan; Yulevich, Igor; Veksler, Dekel; Kleiner, Vladimir; Brongersma, Mark L; Hasman, Erez

    2016-06-01

    The shared-aperture phased antenna array developed in the field of radar applications is a promising approach for increased functionality in photonics. The alliance between the shared-aperture concepts and the geometric phase phenomenon arising from spin-orbit interaction provides a route to implement photonic spin-control multifunctional metasurfaces. We adopted a thinning technique within the shared-aperture synthesis and investigated interleaved sparse nanoantenna matrices and the spin-enabled asymmetric harmonic response to achieve helicity-controlled multiple structured wavefronts such as vortex beams carrying orbital angular momentum. We used multiplexed geometric phase profiles to simultaneously measure spectrum characteristics and the polarization state of light, enabling integrated on-chip spectropolarimetric analysis. The shared-aperture metasurface platform opens a pathway to novel types of nanophotonic functionality. PMID:27103668

  2. Multifunctional thin film sensor system as monitoring system in production

    NASA Astrophysics Data System (ADS)

    Biehl, Saskia; Rumposch, Christian; Paetsch, Nancy

    2015-05-01

    The two most important measurement categories in production are temperature and load. Therefore commercial sensors are applied in machinery as near as possible to the working parts. For a cost efficient production the integration of sensor elements directly on top of the surface in the heavily loaded regions is essential to get the real temperature and load distributions during the production process. Therefore a new multifunctional thin film sensor system is in development. This multilayer system combines thermoresistive sensor structures with piezoresistive ones and exists out of wear resistant carbon based layers [1, 2, 3, 4, 5]. The sensor data will lead to a deeper process understanding, to optimization of simulation tools, to reduction of rejects and to an improvement of flexibility in production.

  3. Multifunctional in vivo imaging of pancreatic islets during diabetes development.

    PubMed

    Li, Ge; Wu, Binlin; Ward, Meliza G; Chong, Angie C N; Mukherjee, Sushmita; Chen, Shuibing; Hao, Mingming

    2016-07-15

    Pancreatic islet dysfunction leading to insufficient glucose-stimulated insulin secretion triggers the clinical onset of diabetes. How islet dysfunction develops is not well understood at the cellular level, partly owing to the lack of approaches to study single islets longitudinally in vivo Here, we present a noninvasive, high-resolution system to quantitatively image real-time glucose metabolism from single islets in vivo, currently not available with any other method. In addition, this multifunctional system simultaneously reports islet function, proliferation, vasculature and macrophage infiltration in vivo from the same set of images. Applying our method to a longitudinal high-fat diet study revealed changes in islet function as well as alternations in islet microenvironment. More importantly, this label-free system enabled us to image real-time glucose metabolism directly from single human islets in vivo for the first time, opening the door to noninvasive longitudinal in vivo studies of healthy and diabetic human islets. PMID:27270669

  4. Exploring multifunctional potential of commercial ferrofluids by magnetic particle hyperthermia

    NASA Astrophysics Data System (ADS)

    Sakellari, Despoina; Mathioudaki, Stella; Kalpaxidou, Zoi; Simeonidis, Konstantinos; Angelakeris, Makis

    2015-04-01

    In this work we examine a selection of commercially available magnetic iron oxide nanoparticles as candidates for magnetic particle hyperthermia applications combining their primary modality with additional heat triggered actions. Contrary to lab-made magnetic nanoparticles, commercial ferrofluids may be rapidly pushed through the medical approval processes since their applicability has already been addressed successfully (i.e., formulation, reproducibility, toxicity and quality assurance) in conjunction with the strong companies‧ drive in the fast delivery of the new therapy to the patient. Four samples are under study with variable hydrodynamic diameters from two companies (Micromod and Chemicell) consisting of iron-oxide magnetic nanoparticles. The tunable magnetic heating characteristics of the ferrofluids were correlated with particle, field and colloidal solution features. Our work revealed a size-dependent magnetic heating efficiency together with fast thermal response, features that are crucial for adequate thermal efficiency combined with minimum treatment duration and show the potential of such materials as multifunctional theranostic agents.

  5. Mussel-inspired dendritic polymers as universal multifunctional coatings.

    PubMed

    Wei, Qiang; Achazi, Katharina; Liebe, Hendrik; Schulz, Andrea; Noeske, Paul-Ludwig Michael; Grunwald, Ingo; Haag, Rainer

    2014-10-20

    A rapid and universal approach for multifunctional material coatings was developed based on a mussel-inspired dendritic polymer. This new kind of polymer mimics not only the functional groups of mussel foot proteins (mfps) but also their molecular weight and molecular structure. The large number of catechol and amine groups set the basis for heteromultivalent anchoring and crosslinking. The molecular weight reaches 10 kDa, which is similar to the most adhesive mussel foot protein mfp-5. Also, the dendritic structure exposes its functional groups on the surface like the folded proteins. As a result, a very stable coating can be prepared on virtually any type of material surface within 10 min by a simple dip-coating method, which is as fast as the formation of mussel byssal threads in nature. PMID:25200129

  6. Complex metal borohydrides: multifunctional materials for energy storage and conversion

    NASA Astrophysics Data System (ADS)

    Mohtadi, Rana; Remhof, Arndt; Jena, Puru

    2016-09-01

    With the limited supply of fossil fuels and their adverse effect on the climate and the environment, it has become a global priority to seek alternate sources of energy that are clean, abundant, and sustainable. While sources such as solar, wind, and hydrogen can meet the world’s energy demand, considerable challenges remain to find materials that can store and/or convert energy efficiently. This topical review focuses on one such class of materials, namely, multi-functional complex metal borohydrides that not only have the ability to store sufficient amount of hydrogen to meet the needs of the transportation industry, but also can be used for a new generation of metal ion batteries and solar cells. We discuss the material challenges in all these areas and review the progress that has been made to address them, the issues that still need to be resolved and the outlook for the future.

  7. Multifunctional Materials Used in Automotive Industry: A Critical Review

    NASA Astrophysics Data System (ADS)

    Salonitis, Konstantinos; Pandremenos, John; Paralikas, John; Chryssolouris, George

    Nowadays, advanced materials and related processes in the automotive industry, are more widely used, leading to an effort towards reducing weight and fuel consumption. The use of such advanced materials and technologies tends to increase the cost. Multifunctional materials (MFMs) and related processing technologies aim at overcoming this increase of cost by exploiting the high level of functional integration. MFMs are designed so as to meet specific requirements through tailored properties. The use of such materials, in the automotive body construction, can help reduce produced parts, lightweight design, high level of integration of functionalities, advancements in mechanical properties of structures etc. In the current study, there is a clear definition of MFMs, and a critical view of such materials used both in the automotive body construction and in other industrial applications.

  8. Photonic spin-controlled multifunctional shared-aperture antenna array

    NASA Astrophysics Data System (ADS)

    Maguid, Elhanan; Yulevich, Igor; Veksler, Dekel; Kleiner, Vladimir; Brongersma, Mark L.; Hasman, Erez

    2016-06-01

    The shared-aperture phased antenna array developed in the field of radar applications is a promising approach for increased functionality in photonics. The alliance between the shared-aperture concepts and the geometric phase phenomenon arising from spin-orbit interaction provides a route to implement photonic spin-control multifunctional metasurfaces. We adopted a thinning technique within the shared-aperture synthesis and investigated interleaved sparse nanoantenna matrices and the spin-enabled asymmetric harmonic response to achieve helicity-controlled multiple structured wavefronts such as vortex beams carrying orbital angular momentum. We used multiplexed geometric phase profiles to simultaneously measure spectrum characteristics and the polarization state of light, enabling integrated on-chip spectropolarimetric analysis. The shared-aperture metasurface platform opens a pathway to novel types of nanophotonic functionality.

  9. Oxytocin – A Multifunctional Analgesic for Chronic Deep Tissue Pain

    PubMed Central

    Goodin, Burel R.; Ness, Timothy J.; Robbins, Meredith T.

    2014-01-01

    The treatment of chronic pain arising from deep tissues is currently inadequate and there is need for new pharmacological agents to provide analgesia. The endogenous paracrine hormone/neurotransmitter oxytocin is intimately involved in the modulation of multiple physiological and psychological functions. Recent experiments have given clear evidence for a role of oxytocin in the modulation of nociception. The present article reviews the existent human and basic science data related to the direct and indirect effects of oxytocin on pain. Due to its analgesic, anxiolytic, antidepressant and other central nervous system effects, there is strong evidence that oxytocin and other drugs acting through the oxytocin receptor could act as multifunctional analgesics with unique therapeutic value. PMID:25345612

  10. Towards Multifunctional Characteristics of Embedded Structures With Carbon Nanotube Yarns

    NASA Technical Reports Server (NTRS)

    Hernandez, Corey D.; Gates, Thomas S.; Kahng, Seun K.

    2006-01-01

    This paper presents recent results on research of achieving multifunctional structures utilizing Carbon Nanotube (CNT) yarns. The investigation centers on creating composite structures with CNT yarns to simultaneously achieve increases in mechanical strength and the ability to sense strain. The CNT yarns used in our experiments are of the single-ply and two-ply variety with the single-ply yarns having diameters on the order of 10-20 m. The yarns are embedded in silicon rubber and polyurethane test specimens. Mechanical tests show an increase in modulus of elasticity, with an additional weight increase of far less than one-percent. Sensing characteristics of the yarns are investigated on stainless steel test beams in an electrical bridge configuration, and are observed to have a strain sensitivity of 0.7mV/V/1000 micro-strain. Also reported are measurements of the average strain distribution along the direction of the CNT yarns on square silicon rubber membranes.

  11. Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality.

    PubMed

    Soliveres, Santiago; van der Plas, Fons; Manning, Peter; Prati, Daniel; Gossner, Martin M; Renner, Swen C; Alt, Fabian; Arndt, Hartmut; Baumgartner, Vanessa; Binkenstein, Julia; Birkhofer, Klaus; Blaser, Stefan; Blüthgen, Nico; Boch, Steffen; Böhm, Stefan; Börschig, Carmen; Buscot, Francois; Diekötter, Tim; Heinze, Johannes; Hölzel, Norbert; Jung, Kirsten; Klaus, Valentin H; Kleinebecker, Till; Klemmer, Sandra; Krauss, Jochen; Lange, Markus; Morris, E Kathryn; Müller, Jörg; Oelmann, Yvonne; Overmann, Jörg; Pašalić, Esther; Rillig, Matthias C; Schaefer, H Martin; Schloter, Michael; Schmitt, Barbara; Schöning, Ingo; Schrumpf, Marion; Sikorski, Johannes; Socher, Stephanie A; Solly, Emily F; Sonnemann, Ilja; Sorkau, Elisabeth; Steckel, Juliane; Steffan-Dewenter, Ingolf; Stempfhuber, Barbara; Tschapka, Marco; Türke, Manfred; Venter, Paul C; Weiner, Christiane N; Weisser, Wolfgang W; Werner, Michael; Westphal, Catrin; Wilcke, Wolfgang; Wolters, Volkmar; Wubet, Tesfaye; Wurst, Susanne; Fischer, Markus; Allan, Eric

    2016-08-25

    Many experiments have shown that loss of biodiversity reduces the capacity of ecosystems to provide the multiple services on which humans depend. However, experiments necessarily simplify the complexity of natural ecosystems and will normally control for other important drivers of ecosystem functioning, such as the environment or land use. In addition, existing studies typically focus on the diversity of single trophic groups, neglecting the fact that biodiversity loss occurs across many taxa and that the functional effects of any trophic group may depend on the abundance and diversity of others. Here we report analysis of the relationships between the species richness and abundance of nine trophic groups, including 4,600 above- and below-ground taxa, and 14 ecosystem services and functions and with their simultaneous provision (or multifunctionality) in 150 grasslands. We show that high species richness in multiple trophic groups (multitrophic richness) had stronger positive effects on ecosystem services than richness in any individual trophic group; this includes plant species richness, the most widely used measure of biodiversity. On average, three trophic groups influenced each ecosystem service, with each trophic group influencing at least one service. Multitrophic richness was particularly beneficial for 'regulating' and 'cultural' services, and for multifunctionality, whereas a change in the total abundance of species or biomass in multiple trophic groups (the multitrophic abundance) positively affected supporting services. Multitrophic richness and abundance drove ecosystem functioning as strongly as abiotic conditions and land-use intensity, extending previous experimental results to real-world ecosystems. Primary producers, herbivorous insects and microbial decomposers seem to be particularly important drivers of ecosystem functioning, as shown by the strong and frequent positive associations of their richness or abundance with multiple ecosystem services

  12. Permeation of multifunctional acrylates through selected protective glove materials.

    PubMed

    Renard, E P; Goydan, R; Stolki, T

    1992-02-01

    In support of the Premanufacture Notification (PMN) program of the Environmental Protection Agency's Office of Toxic Substances, the resistance of three glove materials to permeation by multifunctional acrylate compounds was evaluated through a program for the Office of Research and Development. Several recent PMN submissions relate to multifunctional acrylates and essentially no permeation data are available for this class of compounds. To better understand permeation behavior, tests were conducted with trimethylolpropane triacrylate (TMPTA), 1,6-hexanediol diacrylate (HDDA), and two mixtures of HDDA with 2-ethylhexyl acrylate (EHA). Because of the low vapor pressure and low water solubility of these compounds, the tests were conducted by using ASTM Method F739-85 with a silicone rubber sheeting material as the collection medium. Tests were performed at 20 degrees C with butyl, natural, and nitrile rubber glove materials. None of the acrylate compounds nor mixtures was found to permeate the butyl or nitrile rubber under the test conditions. Permeation through the natural rubber was observed in tests with pure HDDA, a 50% HDDA/50% EHA mixture, and a 25% HDDA/75% EHA mixture. TMPTA permeation through the natural rubber was also detected, but only in one of the triplicate tests after the 360-480 min sampling interval. For pure HDDA, the breakthrough detection time was 30-60 min and the steady-state permeation rate was 0.92 micrograms/cm2-min. For the HDDA/EHA mixtures, permeation of both mixture components was detected during the same sampling interval in each test. The breakthrough detection time was 30-60 min for the 50/50 mixture and from 15-30 to 30-60 min for the 25/75 mixture.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1543127

  13. Impacts of the Residential Conservation Service program on residential solar developments

    SciTech Connect

    Potter, T.; Bircher, T.

    1981-04-01

    The roles of the various participants in the Residential Conservation Service (RCS) program are examined, with special attention to their potential influence on the program's effectiveness in accelerating solar commercialization. Cooperation and support of the participants will be necessary for the information and implementation assistance goals of the program to be achieved, but resistance and obstructions are noted.

  14. Bullying in Adolescent Residential Care: The Influence of the Physical and Social Residential Care Environment

    ERIC Educational Resources Information Center

    Sekol, Ivana

    2016-01-01

    Background: To date, no study examined possible contributions of environmental factors to bullying and victimization in adolescent residential care facilities. Objective: By testing one part of the Multifactor Model of Bullying in Secure Setting (MMBSS; Ireland in "Int J Adolesc Med Health" 24(1):63-68, 2012), this research examined the…

  15. Improving residential miscellaneous electrical load modeling

    NASA Astrophysics Data System (ADS)

    Burgett, Joseph M.

    Over the past 30 years, the intensity of all major energy use categories has decreased in the residential market with the exception of miscellaneous electrical loads (MELs). MELs include primarily 120V plug-loads and some hard wired loads. MELs stand alone as the only category in which energy intensity has steadily increased over time. While MELs constitute approximately 15% - 25% of a typical home's total energy use, it is projected to increase to 36% by 2020. Despite the significant percentage of the home's total load, MELs are the least researched energy end use category and most poorly modeled. The Home Energy Rating System (HERS) index is the most widely used residential energy rating system and uses a simple square foot multiplier to model MELs. This study improves upon the HERS model by including occupant characteristics as part of the MEL model. This "new model" was created by regressing and explanatory equation from the Energy Information Agency's Residential Energy Consumption Survey (RECS). The RECS has a very large sample size of 12,083 respondents who answered over 90 pages of questions related to home structure, appliances they own and demographical information. The information provided by the respondents was used to calculate a MEL for all the RECS households. A stepwise regression process was used to create a model that included size of the home, household income, number of household members and presence of a home business to predict the MEL. The new model was then tested on 24 actual homes to compare its predictive power with the HERS model. The new model more closely predicted the actual MEL for 17 of the 24 test houses (71%). Additionally, the standard deviation or the "tightness of fit" of the new model was less than half of the HERS model when used on the RECS respondents. What this study found was that using occupant characteristics to supplement a square foot multiplier significantly increased the precision of MEL modeling.

  16. Strategy Guideline. High Performance Residential Lighting

    SciTech Connect

    Holton, J.

    2012-02-01

    This report has been developed to provide a tool for the understanding and application of high performance lighting in the home. The strategies featured in this guide are drawn from recent advances in commercial lighting for application to typical spaces found in residential buildings. This guide offers strategies to greatly reduce lighting energy use through the application of high quality fluorescent and light emitting diode (LED) technologies. It is important to note that these strategies not only save energy in the home but also serve to satisfy the homeowner’s expectations for high quality lighting.

  17. Making the most of residential photovoltaic systems

    SciTech Connect

    Moon, S.; Parker, D.; Hayter, S.

    1999-10-18

    Making the Most of Residential Photovoltaic Systems, was recently produced by NREL Communications and Public Affairs. It showcases a demonstration project in Florida that produced some remarkable results by incorporating both energy efficiency and photovoltaic systems into newly built housing. The brochure points up the benefits of making wise personal choices about energy use, and how large-scale use of advanced energy technologies can benefit the nation. This is one of a series of brochures that presents stimulating information about photovoltaics, with a goal of helping to push this technology into the power-generation mix in different utilities, communities, and states.

  18. Residential lighting: Use and potential savings

    SciTech Connect

    1996-09-01

    The 1993 Residential Energy Consumption Survey (RECS) was the first to permit the estimation of annual kilowatt hours (kWh) used for lighting. The survey contained more detailed questions about the number of indoor lights used for specific amounts of time and more detailed questions about the use of outdoor lights than did previous surveys. In addition to these basic questions on the Household Questionnaire, the 1993 RECS also included a supplementary questionnaire, administered to a subset of households, that contained more detailed information about the types of lights used in the household, the rooms in which they were located, and the amount of time they were used.

  19. Residential Energy Consumption Survey: Quality Profile

    SciTech Connect

    1996-03-01

    The Residential Energy Consumption Survey (RECS) is a periodic national survey that provides timely information about energy consumption and expenditures of U.S. households and about energy-related characteristics of housing units. The survey was first conducted in 1978 as the National Interim Energy Consumption Survey (NIECS), and the 1979 survey was called the Household Screener Survey. From 1980 through 1982 RECS was conducted annually. The next RECS was fielded in 1984, and since then, the survey has been undertaken at 3-year intervals. The most recent RECS was conducted in 1993.

  20. Practical Diagnostics for Evaluating Residential Commissioning Metrics

    SciTech Connect

    Wray, Craig; Walker, Iain; Siegel, Jeff; Sherman, Max

    2002-06-11

    In this report, we identify and describe 24 practical diagnostics that are ready now to evaluate residential commissioning metrics, and that we expect to include in the commissioning guide. Our discussion in the main body of this report is limited to existing diagnostics in areas of particular concern with significant interactions: envelope and HVAC systems. These areas include insulation quality, windows, airtightness, envelope moisture, fan and duct system airflows, duct leakage, cooling equipment charge, and combustion appliance backdrafting with spillage. Appendix C describes the 83 other diagnostics that we have examined in the course of this project, but that are not ready or are inappropriate for residential commissioning. Combined with Appendix B, Table 1 in the main body of the report summarizes the advantages and disadvantages of all 107 diagnostics. We first describe what residential commissioning is, its characteristic elements, and how one might structure its process. Our intent in this discussion is to formulate and clarify these issues, but is largely preliminary because such a practice does not yet exist. Subsequent sections of the report describe metrics one can use in residential commissioning, along with the consolidated set of 24 practical diagnostics that the building industry can use now to evaluate them. Where possible, we also discuss the accuracy and usability of diagnostics, based on recent laboratory work and field studies by LBNL staff and others in more than 100 houses. These studies concentrate on evaluating diagnostics in the following four areas: the DeltaQ duct leakage test, air-handler airflow tests, supply and return grille airflow tests, and refrigerant charge tests. Appendix A describes those efforts in detail. In addition, where possible, we identify the costs to purchase diagnostic equipment and the amount of time required to conduct the diagnostics. Table 1 summarizes these data. Individual equipment costs for the 24

  1. NAT Usage in Residential Broadband Networks

    NASA Astrophysics Data System (ADS)

    Maier, Gregor; Schneider, Fabian; Feldmann, Anja

    Many Internet customers use network address translation (NAT) when connecting to the Internet. To understand the extend of NAT usage and its implications, we explore NAT usage in residential broadband networks based on observations from more than 20,000 DSL lines. We present a unique approach for detecting the presence of NAT and for estimating the number of hosts connected behind a NAT gateway using IP TTLs and HTTP user-agent strings. Furthermore, we study when each of the multiple hosts behind a single NAT gateway is active. This enables us to detect simultaneous use. In addition, we evaluate the accuracy of NAT analysis techniques when fewer information is available.

  2. Residential normalcy and environmental experiences of very old people: changes in residential reasoning over time.

    PubMed

    Granbom, Marianne; Himmelsbach, Ines; Haak, Maria; Löfqvist, Charlotte; Oswald, Frank; Iwarsson, Susanne

    2014-04-01

    The decision to relocate in old age is intricately linked to thoughts and desires to stay put. However, most research focuses either on strategies that allow people to age in place or on their reasons for relocation. There is a need for more knowledge on very old peoples' residential reasoning, including thoughts about aging in place and thoughts about relocation as one intertwined process evolving in everyday life. The aim of this study was to explore what we refer to as the process of residential reasoning and how it changes over time among very old people, and to contribute to the theoretical development regarding aging in place and relocation. Taking a longitudinal perspective, data stem from the ENABLE-AGE In-depth Study, with interviews conducted in 2003 followed up in interviews in 2011. The 16 participants of the present study were 80-89years at the time of the first interview. During analysis the Theoretical Model of Residential Normalcy by Golant and the Life Course Model of Environmental Experience by Rowles & Watkins were used as sensitizing concepts. The findings revealed changes in the process of residential reasoning that related to a wide variety of issues. Such issues included the way very old people use their environmental experience, their striving to build upon or dismiss attachment to place, and their attempts to maintain or regain residential normalcy during years of declining health and loss of independence. In addition, the changes in reasoning were related to end-of-life issues. The findings contribute to the theoretical discussion on aging in place, relocation as a coping strategy, and reattachment after moving in very old age. PMID:24655669

  3. Electron-beam-directed vapor deposition of multifunctional structures for electrochemical storage

    NASA Astrophysics Data System (ADS)

    Queheillalt, Douglas T.; Hass, Derek D.; Wadley, Haydn N. G.

    2002-07-01

    Multifunctional structures are those, which combine load- bearing support in addition to additional functions such as mechanical actuation, distributed power supply or thermal management. Electron beam - directed vapor deposition technology has been used to investigate deposition methodologies for two multifunctional battery concepts: a linear/truss base nickel - metal hydride and a fiber based solid-state Li+ ion multifunctional battery. Porous nickel coatings for the cathodes and porous rare earth metal coatings based on La and Ni or Ti and Zr for the anodes are being investigated for the nickel - metal hydride system; where LiV2O5, LiPON, and Sn3N4 are being investigated for the Li+ ion based system. Electron beam - directed vapor deposition is being used for deposition of all cathode/anode structures to provide an economical method for the development of these novel multifunctional structures.

  4. Multifunctional Porous Graphene for High-Efficiency Steam Generation by Heat Localization.

    PubMed

    Ito, Yoshikazu; Tanabe, Yoichi; Han, Jiuhui; Fujita, Takeshi; Tanigaki, Katsumi; Chen, Mingwei

    2015-08-01

    Multifunctional nanoporous graphene is realized as a heat generator to convert solar illumination into high-energy steam. The novel 3D nanoporous graphene demonstrates a highly energy-effective steam generation with an energy conversation of 80%. PMID:26079440

  5. EVALUATION OF A MULTIFUNCTIONAL VALVE ASSEMBLY IN A DIRECT EXPANSION REFRIGERATION SYSTEM REPORT

    EPA Science Inventory

    The report describes the performance, including energy consumption, of a refrigeration system incorporating a multifunctional valve (MXV assembly). The MXV assembly (consisting of additional liquid line, an XTC valve, and a larger thermostatic expansion valve) was installed on al...

  6. 42 CFR 483.354 - General requirements for psychiatric residential treatment facilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Psychiatric Residential Treatment Facilities Providing Inpatient Psychiatric Services for Individuals Under Age 21 § 483.354 General requirements for psychiatric residential treatment facilities. A...

  7. 42 CFR 483.354 - General requirements for psychiatric residential treatment facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Psychiatric Residential Treatment Facilities Providing Inpatient Psychiatric Services for Individuals Under Age 21 § 483.354 General requirements for psychiatric residential treatment facilities. A...

  8. 42 CFR 483.354 - General requirements for psychiatric residential treatment facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Psychiatric Residential Treatment Facilities Providing Inpatient Psychiatric Services for Individuals Under Age 21 § 483.354 General requirements for psychiatric residential treatment facilities. A...

  9. 42 CFR 483.354 - General requirements for psychiatric residential treatment facilities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Psychiatric Residential Treatment Facilities Providing Inpatient Psychiatric Services for Individuals Under Age 21 § 483.354 General requirements for psychiatric residential treatment facilities. A...

  10. 42 CFR 483.354 - General requirements for psychiatric residential treatment facilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Psychiatric Residential Treatment Facilities Providing Inpatient Psychiatric Services for Individuals Under Age 21 § 483.354 General requirements for psychiatric residential treatment facilities. A...

  11. Existence and comparison results for fixed points of multifunctions with applications to normal-form games

    NASA Astrophysics Data System (ADS)

    Heikkila, S.

    2007-08-01

    In this paper we apply generalized iteration methods to prove comparison results which show how fixed points of a multifunction can be bounded by least and greatest fixed points of single-valued functions. As an application we prove existence and comparison results for fixed points of multifunctions. These results are applied to normal-form games, by proving existence and comparison results for pure and mixed Nash equilibria and their utilities.

  12. Dynamic pricing? Not so fast. a residential consumer perspective

    SciTech Connect

    Alexander, Barbara R.

    2010-07-15

    With the installation of smart metering, will residential customers be moved to ''dynamic'' pricing? Some supporters of changing residential rate design from a fixed and stable rate structure believe customers should be required to take electric service with time-variant price signals. Not so fast, though. There are real implications associated with this strategy. (author)

  13. Classification of Residential Facilities for Mentally Retarded People. Brief #24.

    ERIC Educational Resources Information Center

    Hill, B. K.; Lakin, K. C.

    This paper describes the development of a taxonomy of residential facilities for mentally retarded people based on program model, size, and operation. Data are presented on the use of the classification system in a national survey of 15,633 residential facilities for mentally retarded persons in the United States. Program models are defined…

  14. Residential Education as an Option for At-Risk Youth.

    ERIC Educational Resources Information Center

    Beker, Jerome, Ed.; Magnuson, Douglas, Ed.

    Residential treatment centers have always steered a course between bureaucracy and anarchy. The conventional professional wisdom in the United States holds that residential group care programs for children and youth are intrinsically flawed. This volume seeks to remedy this perception by making a case for the adoption of Israeli and European…

  15. Effect of Organizational Climate on Youth Outcomes in Residential Treatment

    ERIC Educational Resources Information Center

    Jordan, Neil; Leon, Scott C.; Epstein, Richard A.; Durkin, Elizabeth; Helgerson, Jena; Lakin-Starr, Brittany L.

    2009-01-01

    This study examined the association between organizational climate and changes in internalizing and externalizing behavior for youth in residential treatment centers (RTCs). The sample included 407 youth and 349 front-line residential treatment staff from 17 RTCs in Illinois. Youth behavior was measured using the Child Functional Assessment Rating…

  16. Building a Community of Learning through Early Residential Fieldwork

    ERIC Educational Resources Information Center

    Walsh, Cathy; Larsen, Carl; Parry, Damian

    2014-01-01

    The positioning of residential fieldwork early in students' higher education is an established way of attempting to build and engage them in a community of learning. In the study reported here, the benefits of such early residential fieldwork were investigated using Krausse and Coates's seven scales of engagement. These scales consider a…

  17. Substance Use among Young People Living in Residential State Care

    ERIC Educational Resources Information Center

    McCrystal, Patrick; Percy, Andrew; Higgins, Kathryn

    2008-01-01

    Existing empirical evidence on substance use among young people living in residential state care during adolescence is comparatively limited. This paper reports on substance use trends of young people living in residential state care during three annual data-sweeps when aged 14, 15 and 16 years. A repeated cross-sectional research design was…

  18. Behind Closed Doors: Stories from the Kamloops Indian Residential School.

    ERIC Educational Resources Information Center

    Jack, Agness, Ed.

    Thirty-two Canada Natives who attended the Kamloops Indian Residential School agreed to share their stories in the form of this book. In this way, their families and communities could learn and understand what happened at the school, and all Canadians could know the truth about residential schools so that history is never repeated. Kamloops Indian…

  19. Differences in Outcome Trajectories of Children in Residential Treatment

    ERIC Educational Resources Information Center

    Helgerson, Jena; Martinovich, Zoran; Durkin, Elizabeth; Lyons, John S.

    2005-01-01

    At least three circumstances have converged to focus attention on the outcomes associated with residential treatment. First, the reduction in lengths of stay in the psychiatric hospital has resulted in residential treatment becoming the most expensive service on a per episode basis. Second, the increasing emphasis on the identification and use of…

  20. Exploring the Relationship between Conduct Disorder and Residential Treatment Outcomes

    ERIC Educational Resources Information Center

    Shabat, Julia Cathcart; Lyons, John S.; Martinovich, Zoran

    2008-01-01

    We examined the differential outcomes in residential treatment for youths with conduct disorder (CD)--with special attention paid to interactions with age and gender--in a sample of children and adolescents in 50 residential treatment centers and group homes across Illinois. Multi-disciplinary teams rated youths ages 6-20 (N = 457) on measures of…

  1. Residential Satisfaction and Levels of Environment in Students' Residences

    ERIC Educational Resources Information Center

    Amole, Dolapo

    2009-01-01

    This study investigates the relationship between residential satisfaction and levels of the residential environment. Specifically, it identifies the levels of environment to which users respond in relation to satisfaction, how significant satisfaction is across levels of environment, and the dimensions of satisfaction across the levels. The study…

  2. Residential Preferences: What's Terrorism Got to Do with It?

    ERIC Educational Resources Information Center

    Kay, David; Geisler, Charles; Bills, Nelson

    2010-01-01

    Security has long been recognized as an element in residential preference and its relative importance has risen with fear of extremist attacks on U.S. cities. Using polling data from 2004, this research investigates whether the security breaches of 9/11 in New York City influenced residential preferences in New York State. Our results confirm that…

  3. 20 CFR 638.514 - Residential support services.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Residential support services. 638.514 Section 638.514 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR JOB CORPS PROGRAM UNDER TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Center Operations § 638.514 Residential support services. The center operator...

  4. 20 CFR 638.514 - Residential support services.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Residential support services. 638.514 Section 638.514 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR JOB CORPS PROGRAM UNDER TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Center Operations § 638.514 Residential support services. The center operator...

  5. Residential Learning Communities. What Works Clearinghouse Intervention Report

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2014

    2014-01-01

    Residential learning communities in postsecondary education, also known as living-learning programs, aim to improve student learning and success by integrating students' academic and daily living environments. Students participating in these programs live together (usually in a residential dormitory), take certain classes together, and engage…

  6. ANALYSIS OF EMISSIONS FROM RESIDENTIAL NATURAL GAS FURNACES

    EPA Science Inventory

    The paper gives emissions data from residential natural-gas furnaces and compares selected data to emissions data from residential oil furnaces and woodstoves. atural-gas furnace emissions data are given for carbon monoxide (CO), unburned hydrocarbons, aldehydes, volatile and sem...

  7. The Role of Residential Segregation in Contemporary School Segregation

    ERIC Educational Resources Information Center

    Frankenberg, Erica

    2013-01-01

    Inaction to address housing segregation in metropolitan areas has resulted in persistently high levels of residential segregation. As the Supreme Court has recently limited school districts' voluntary integration efforts, this article considers the role of residential segregation in maintaining racially isolated schools, namely what is known…

  8. No End of Grief: Indian Residential Schools in Canada.

    ERIC Educational Resources Information Center

    Grant, Agnes

    This book documents and comments on what is known about the Indian residential school era in Canada. The aftermath of this era has exacted a huge toll, both in the human suffering of First Nations and on Canadian society in general, but understanding the impact of residential schools can aid the healing process. Chapters are: (1) "Examining the…

  9. The Future of Family Engagement in Residential Care Settings

    ERIC Educational Resources Information Center

    Affronti, Melissa L.; Levison-Johnson, Jody

    2009-01-01

    Residential programs for children and youth are increasingly implementing engagement strategies to promote family-centered and family-driven models of care (Leichtman, 2008). The practice of engagement is a fairly new area of research, especially in residential care. Driven by their goal to increase the use of state-of-the-art family engagement…

  10. Residential Care in Illinois: Trends and Alternatives. Final Report

    ERIC Educational Resources Information Center

    Budde, Stephen; Mayer, Susan; Zinn, Andrew; Lippold, Melissa; Avrushin, Adam; Bromberg, Ava; Goerge, Robert; Courtney, Mark

    2004-01-01

    In this multi-faceted exploratory study, administrative data were used to examine trends in residential care utilization by the Illinois Department of Children and Family Services (DCFS) and youth outcomes from 1993 to 2003. Multivariate analyses were conducted to determine the factors associated with entry to residential care and…

  11. Examination of Negative Peer Contagion in a Residential Care Setting

    ERIC Educational Resources Information Center

    Huefner, Jonathan C.; Ringle, Jay L.

    2012-01-01

    There has been ongoing concern about the negative impact of residential treatment on youth in care. Research examining the impact of negative peer influence in juvenile justice, education, and residential care settings is reviewed. A study was conducted to examine the impact of negative peer contagion on the level of problem behavior in a…

  12. Family-Centered Residential Treatment: Knowledge, Research, and Values Converge

    ERIC Educational Resources Information Center

    Walter, Uta M.; Petr, Christopher G.

    2008-01-01

    Although the evidence base for the effectiveness of residential treatment is still very limited, a review of the literature reveals family-centered residential care as an emerging best practice. Synthesizing knowledge from research, families, youth, professionals, as well as values put forth in the standards by accrediting organizations, this…

  13. 10 CFR 429.21 - Residential clothes dryers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Residential clothes dryers. 429.21 Section 429.21 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION CERTIFICATION, COMPLIANCE, AND ENFORCEMENT FOR CONSUMER PRODUCTS AND COMMERCIAL AND INDUSTRIAL EQUIPMENT Certification § 429.21 Residential clothes dryers. (a) Sampling plan for selection of units for...

  14. Minimizing Public Costs of Residential Growth. Coping With Growth.

    ERIC Educational Resources Information Center

    Weber, Bruce; Beck, Richard

    Rapid residential growth in rural areas or on the fringes of urban areas brings both costs and benefits. Seven factors determine whether new homes and subdivisions generate more revenues than expenditures. Local governments can substantially influence four of these seven factors in order to reduce the public costs of residential growth. Less…

  15. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... which he received a loan of $5,000 from the Federal Solar-Energy and Energy Conservation Bank. Assume... 26 Internal Revenue 1 2011-04-01 2009-04-01 true Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or...

  16. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... which he received a loan of $5,000 from the Federal Solar-Energy and Energy Conservation Bank. Assume... 26 Internal Revenue 1 2014-04-01 2013-04-01 true Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or...

  17. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... which he received a loan of $5,000 from the Federal Solar-Energy and Energy Conservation Bank. Assume... 26 Internal Revenue 1 2013-04-01 2013-04-01 false Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or...

  18. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... which he received a loan of $5,000 from the Federal Solar-Energy and Energy Conservation Bank. Assume... 26 Internal Revenue 1 2012-04-01 2012-04-01 false Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or...

  19. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... which he received a loan of $5,000 from the Federal Solar-Energy and Energy Conservation Bank. Assume... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or...

  20. Residential Group Care Quarterly. Volume 7, Number 1, Summer 2006

    ERIC Educational Resources Information Center

    Michael, Jennifer, Ed.

    2006-01-01

    "Residential Group Care Quarterly" is published four times a year by the Child Welfare League of America (CWLA). This issue of "Residential Group Care Quarterly" contains the following articles: (1) Building Bridges between Service Delivery Providers, Families, and Youth (Lloyd Bullard); (2) The Promise of Professionalism Arrives in Practice:…

  1. 2011 Residential Energy Efficiency Technical Update Meeting Summary Report

    SciTech Connect

    none,

    2011-11-01

    This report provides an overview of the U.S. Department of Energy Building America program's Summer 2011 Residential Energy Efficiency Technical Update Meeting. This meeting was held on August 9-11, 2011, in Denver, Colorado, and brought together more than 290 professionals representing organizations with a vested interest in energy efficiency improvements in residential buildings.

  2. Residential Mobility, Inhibitory Control, and Academic Achievement in Preschool

    ERIC Educational Resources Information Center

    Schmitt, Sara A.; Finders, Jennifer K.; McClelland, Megan M.

    2015-01-01

    Research Findings: The present study investigated the direct effects of residential mobility on children's inhibitory control and academic achievement during the preschool year. It also explored fall inhibitory control and academic skills as mediators linking residential mobility and spring achievement. Participants included 359 preschool…

  3. Residential Mobility, Inhibitory Control, and Academic Achievement in Preschool

    ERIC Educational Resources Information Center

    Schmitt, Sara A.; Finders, Jennifer K.; McClelland, Megan M.

    2015-01-01

    The present study investigated the direct effects of residential mobility on children's inhibitory control and academic achievement during the preschool year. It also explored fall inhibitory control and academic skills as mediators linking residential mobility and spring achievement. Participants included 359 preschool children (49% female)…

  4. The Education of Youth in DFY Residential Programs.

    ERIC Educational Resources Information Center

    New York State Div. for Youth, Albany.

    This report describes educational programs at New York State Division for Youth (DFY) residential facilities. It provides an overview of the services offered to prepare adjudicated youth for successful return to the community. The Division's residential education services encourage student growth in cognitive, affective, and vocational skill…

  5. The Severely Disturbed Adolescent; Inpatient, Residential, and Hospital Treatment.

    ERIC Educational Resources Information Center

    Easson, William M.

    The text is an attempt to clarify specific indications for hospital treatment and to highlight the type of adolescent disturbance that might be helped in an inpatient therapeutic environment. Chapters discuss the prescription of residential treatment, the therapeutic facilities of a residential unit for disturbed adolescents, the continued…

  6. 20. VIEW OF RESIDENTIAL BUILDINGS TAKEN IN 1911 LOOKING NORTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. VIEW OF RESIDENTIAL BUILDINGS TAKEN IN 1911 LOOKING NORTHEAST PROBABLY FROM SWAN FALLS DAM. FROM LEFT TO RIGHT, RESIDENTIAL BUILDINGS ARE COTTAGE 101, THE COTTAGE THAT BURNED IN 1921 (AND WAS REPLACED WITH COTTAGE 231), AND THE CLUB HOUSE. OTHER BUILDINGS IN FOREGROUND ARE STOREHOUSES AND SHOPS. - Swan Falls Village, Snake River, Kuna, Ada County, ID

  7. Black Residential Segregation: Impact of State Licensing Laws.

    ERIC Educational Resources Information Center

    Darden, Joe T.

    1982-01-01

    Compared the level of Black residential segregation among two groups of States: those whose real estate licensing laws contain explicit fair housing or anti-discrimination provisions, and those whose licensing laws contain no such provisions. Found that State licensing laws have no significant impact on Black residential discrimination. (GC)

  8. Adolescent Perception of Family Climate and Adaptation to Residential Schooling.

    ERIC Educational Resources Information Center

    Shulman, Shmuel; Prechter, Eti

    1989-01-01

    Changes in adolescents' perceptions of the family as they adapt to residential schooling were studied for 51 residential and 57 nonresidential tenth graders in a school in Israel. No differences in the perception of family climate were found between the groups, suggesting no change with the individual's act of leaving. (SLD)

  9. Benchmarking the FCI at Illinois State's Residential Life.

    ERIC Educational Resources Information Center

    Cain, David A.

    1998-01-01

    Describes how Office of Residential Life at one university met maintenance challenges facing its residential and food-service facilities. Discusses study conducted in 1992 to evaluate widespread management practices and addresses its findings, including six recommended practices. Examines development and implementation of facilities audit,…

  10. Residential Group Care Quarterly. Volume 7, Number 2, Fall 2006

    ERIC Educational Resources Information Center

    Ruby, Kathy, Ed.

    2006-01-01

    "Residential Group Care Quarterly" is published four times a year by the Child Welfare League of America (CWLA). This issue of "Residential Group Care Quarterly" contains the following articles: (1) Whatever Happened to Sound Clinical Reasoning? (Elizabeth Kohlstaedt); (2) Minorities as Majority Disproportionality in Child Welfare and Juvenile…

  11. Residential Group Care Quarterly. Volume 6, Number 1, Summer 2005

    ERIC Educational Resources Information Center

    Michael, Jennifer, Ed.

    2005-01-01

    This issue of "Residential Group Care Quarterly" includes the following articles: (1) "Residential Treatment: Finding the Appropriate Level of Care" (Shay Bilchik); (2) "Family-Centered Practices" (Rodger McDaniel and Brenden McKinney); and (3) "Can the Community Serve Sex Offenders?" (Point/Counterpoint--Daniel Wallach and Wayne D. Parks).…

  12. Residential Group Care Quarterly. Volume 6, Number 4, Spring 2006

    ERIC Educational Resources Information Center

    Michael, Jennifer, Ed.

    2006-01-01

    "Residential Group Care Quarterly" is published four times a year by the Child Welfare League of America (CWLA). This issue of "Residential Group Care Quarterly" contains the following articles: (1) Strengthening the Culture of Care in Child Care Agencies (Vonda I. Wallace and Jean Carpenter-Williams); (2) Improving Restraint Monitoring with Pulse…

  13. Engineering economic assessment of residential wood heating in NY

    EPA Science Inventory

    We provide insight into the recent resurgence in residential wood heating in New York by: (i) examining the lifetime costs of outdoor wood hydronic heaters (OWHHs) and other whole-house residential wood heat devices,(ii) comparing these lifetime costs with those of competing tech...

  14. The Right to Choose: Achieving Residential Alternatives in the Community.

    ERIC Educational Resources Information Center

    Patterson, Gene, Ed.; Byrne, Richard, Ed.

    The handbook gives guidelines for the development, operation, and evaluation of a community based system of residential facilities for mentally retarded (MR) persons. Directions are given which explain the step-by-step procedure for planning in any community. The idea of a residential service delivery system is described in terms of small…

  15. The Language Functioning of Youth at Entry to Residential Treatment

    ERIC Educational Resources Information Center

    Trout, Alexandra L.; Huscroft-D'Angelo, Jacqueline; DeSalvo, Catherine; Gehringer, Robert

    2011-01-01

    Although much is known about the behavioral and educational characteristics of youth at entry to residential care, little is known about youth language performance. Given the impact of language deficits on outcomes, this study assessed the specific language skills of 70 adolescents at entry to a residential treatment setting. Results revealed…

  16. Residential Group Care Quarterly. Volume 5, Number 1, Summer 2004

    ERIC Educational Resources Information Center

    Kirkwood, Scott, Ed.

    2004-01-01

    This issue of "Residential Group Care Quarterly" contains the following articles: (1) "National Definitions and Data Collection for Residential Care Facilities' Use of Restraint and Seclusion" (Lloyd Bullard); (2) "CWLA Publishes Best Practices in Behavior Support and Intervention Assessment Instrument" (Nupur Gupta); (3) "Initial Findings of an…

  17. 12 CFR 541.23 - Residential real estate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... or residential real property mean: (a) Homes (including a dwelling unit in a multi-family residential property such as a condominium or a cooperative); (b) Combinations of homes and business property (i.e., a... than a home (but which may include homes); (d) Combinations of such real estate and business...

  18. 12 CFR 541.23 - Residential real estate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... or residential real property mean: (a) Homes (including a dwelling unit in a multi-family residential property such as a condominium or a cooperative); (b) Combinations of homes and business property (i.e., a... than a home (but which may include homes); (d) Combinations of such real estate and business...

  19. 12 CFR 541.23 - Residential real estate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... or residential real property mean: (a) Homes (including a dwelling unit in a multi-family residential property such as a condominium or a cooperative); (b) Combinations of homes and business property (i.e., a... than a home (but which may include homes); (d) Combinations of such real estate and business...

  20. Integrating Adolescents with Developmental Disabilities in a Residential Summer Camp.

    ERIC Educational Resources Information Center

    Parker, Mitchell S.

    This paper describes Camp Ramah, a residential summer camp in Central Ontario that offers a one month program for adolescents with developmental disabilities. Up to 15 special needs campers, ages 12-25, participate with up to 400 campers and 150 staff in a residential camping experience. Most campers have mild to moderate mental retardation, some…