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1

Antiphospholipid syndrome: five year follow up.  

PubMed Central

Nineteen patients out of 250 subjects with antiphospholipid antibodies, who had initially presented to the lupus clinic at St Thomas's Hospital, London five or more years ago with a history of venous/arterial occlusions, were entered into the study. The patients were divided into two main groups: I those who remained well without any further thromboembolic complications (n = 10); II those who developed recurrent thrombotic events in the five year period (n = 9). The patients were followed up to determine the relation between the level or the isotype of the anticardiolipin antibodies, or both, to the recurrent thromboembolic events, and the effect of a variety of treatments (corticosteroids, immunosuppression, anticoagulation) in the prevention of further vascular occlusions. Lupus activity over the five year period varied considerably between the two groups--those in group I tending to be relatively inactive compared with those in group II. For some patients in group II thromboembolic events seemed to occur at the time of lupus activity. Antiphospholipid antibodies remained positive in all patients, the levels remaining fairly constant. Levels fell in only one patient in group I and in two in group II. Patients in group II had more systemic lupus erythematosus related disease than those in group I; most were receiving concomitant steroid and immunosuppressive therapy, but this did not seem to protect against the development of further occlusions. All patients were given anticoagulation treatment (warfarin/heparin) or salicylates (low dose aspirin 75 mg daily), or both. Patients with deep vein thromboses developed more complications during anticoagulation therapy than those with cerebrovascular symptoms. Problems in anticoagulation control and recurrent thromboses consequent on warfarin withdrawal despite the administration of subcutaneous heparin were responsible for complications in most patients in group II.

Asherson, R A; Baguley, E; Pal, C; Hughes, G R

1991-01-01

2

Total meniscectomy in adolescents: a 40-year follow-up.  

PubMed

We continued a prospective longitudinal follow-up study of 53 remaining patients who underwent open total meniscectomy as adolescents and who at that time had no other intra-articular pathology of the knee. Their clinical, radiological and patient-reported outcomes are described at a mean follow-up of 40 years (33 to 50). The cohort of patients who had undergone radiological evaluation previously after 30 years were invited for clinical examination, radiological evaluation and review using two patient-reported outcome measures. A total of seven patients (13.2%) had already undergone total knee replacement at the time of follow-up. A significant difference was observed between the operated and non-operated knee in terms of range of movement and osteoarthritis of the tibiofemoral joint, indicating a greater than fourfold relative risk of osteoarthritis at 40 years post-operatively. All patients were symptomatic as defined by the Knee Injury and Osteoarthritis Outcome Score. This study represents the longest follow-up to date and it can be concluded that meniscectomy leads to symptomatic osteoarthritis of the knee later in life, with a resultant 132-fold increase in the rate of total knee replacement in comparison to their geographical and age-matched peers. PMID:23188906

Pengas, I P; Assiotis, A; Nash, W; Hatcher, J; Banks, J; McNicholas, M J

2012-12-01

3

Fifteen-year follow-up of arthroscopic partial meniscectomy  

Microsoft Academic Search

From an original pool of 283 patients, 146 patients who had undergone arthroscopic partial meniscectomy an average of 14.7 years before were followed-up. Lysholm score, Tegner activity level, satisfaction index on a scale of 1 to 10, and standing anteroposterior and flexion weight-bearing radiographs of both knees, were obtained. A physical examination was performed on each knee emphasizing motion, swelling,

Robert T. Burks; Michael H. Metcalf; Robert W. Metcalf

1997-01-01

4

Early-onset schizophrenia: a 15-year follow-up.  

PubMed

The study describes the psychopathological and social outcome of patients treated for schizophrenia in adolescence (mean age at onset 16.0 years/SD 1.52) after a mean follow-up period of 15.4 years (10.2-21.2 years). Out of 55 patients consecutively admitted to hospital, 47 (85 %) could be traced and 39 (71 %) could be re-examined. At follow-up, 33/39 patients (85 %) had had at least one readmission. Full remission of global psychopathological symptoms [Clinical Global Impression (CGI) follow-up. Gender, duration of first inpatient treatment and duration of untreated psychosis were of no predictive value for outcome. The nature of the diagnosis in the first episode strongly predicted the diagnosis given for the whole course after 15 years. In 26/37 cases (70 %), diagnosis at onset and overall diagnoses were the same. Our finding of an incidence of 61% insidious onset is similar to that in adult onset schizophrenia (AOS), but different to very early onset schizophrenia (VEOS), which shows a higher rate of insidious onset, cognitive impairment and poor outcome. Therefore, it seems that VEOS is a special group compared with early onset schizophrenia (EOS) and AOS. PMID:16220219

Röpcke, Bernd; Eggers, Christian

2005-09-01

5

Six year follow up of infants with bacteriuria on screening.  

PubMed Central

OBJECTIVE--To determine the value of screening for bacteriuria in infants with special emphasis on the natural course of untreated asymptomatic bacteriuria, renal growth, and renal damage. DESIGN--Prospective six year follow up of infants with bacteriuria on screening in an unselected infant population. SETTING--Paediatric outpatient clinic. PATIENTS--50 Infants (14 girls, 36 boys) with bacteriuria on screening verified by suprapubic aspiration from an unselected population of 3581 infants in a defined area of Gothenburg. INTERVENTIONS--Children with asymptomatic bacteriuria and normal findings on initial urography were untreated, although other infections were treated. MAIN OUTCOME MEASURES--Culture of urine and determination of C reactive protein concentration every six weeks for the first six months after diagnosis, every three months from six months to two years, and every six months between two and three years; thereafter yearly urine culture. Evaluation of renal concentrating capacity with a desmopressin test; radiological examination, including first and follow up urography and micturition cystourethrography without antibiotic cover; and measurement of renal parenchymal thickness and renal surface area. RESULTS--Of the original 50 infants, 37 (12 girls, 25 boys) were followed up for at least six years. Two infants developed pyelonephritis within two weeks after bacteriuria was diagnosed; the others remained free of symptoms. 45 Infants were untreated; the bacteriuria cleared spontaneously in 36 and in response to antibiotics given for infections in the respiratory tract in eight. Recurrences of bacteriuria were observed in 10 of the 50 children, of whom one had pyelonephritis. No child had more than one recurrence. At follow up urography in 36 of the 50 children (9 girls, 27 boys) after a median of 32 months no child had developed renal damage. First samples tested for renal concentrating capacity showed significantly higher values than those from a reference population (mean SD score 0.50, 95% confidence interval 0.21 to 0.79; p less than 0.001), but the last samples showed no significant difference (mean SD score 0.08, -0.24 to 0.40; p greater than 0.05). CONCLUSIONS--Mass screening for bacteriuria in infancy results primarily in detection of innocent bacteriuric episodes and is not recommended.

Wettergren, B; Hellstrom, M; Stokland, E; Jodal, U

1990-01-01

6

Chemodenervation of strabismic children. A 2- to 5-year follow-up study compared with shorter follow-up.  

PubMed

To determine longer-term efficacy of botulinum treatment, the author examined 85 children younger than 14 years of age who had been treated from November 1982 to February 1984, comparing shorter follow-up (range, 6-24 months) with longer follow-up (range, 2-5.5 years) as of last examination before March 1988. Fifty esotropes meeting the 2-year criteria for follow-up had an average of 35 prism diopters (PD) before and 5 PD after treatment. Twelve exotropes averaged 30 and 5 PD. No long-term complications were discovered. The results are similar to the shorter follow-up and suggest that botulinum is effective in creating a 2- to 5-year stable improvement for strabismic children. PMID:2771359

Magoon, E H

1989-07-01

7

Serial extraction: 20 years of follow-up  

PubMed Central

This paper reports a case treated by a serial extraction program at the mixed dentition stage followed by a corrective orthodontic treatment, with a long-term follow-up period. Twenty years after the interceptive treatment, a harmonious face was observed along with treatment stability in the anterior posterior direction, deep overbite (which has been mentioned as a disadvantage of the serial extraction program), and a small relapse of anterior tooth crowding. All these conditions have been regarded as normal occurrences for most orthodontic treatments with a long-term follow-up period. This case report demonstrated that the establishment of a serial extraction protocol determined relevant esthetic changes that afforded an improvement of the patient's self-esteem, with a positive social impact. Furthermore, the low cost of this protocol permits the use of this therapy with underprivileged populations. It is important to emphasize that an early correction of tooth crowding by this protocol does not guarantee stability, but small relapses do not invalidate its accomplishment.

de ALMEIDA, Renato Rodrigues; de ALMEIDA, Marcio Rodrigues; OLTRAMARI-NAVARRO, Paula Vanessa Pedron; CONTI, Ana Claudia de Castro Ferreira; NAVARRO, Ricardo de Lima; de SOUZA, Karen Regina Siqueira

2012-01-01

8

Asthma increase among farmers: a 12-year follow-up  

PubMed Central

Respiratory disease is a well known health hazard for farmers, but the long-term prognosis is less well known. This is a 12-year follow-up of an investigation of Swedish farmers, most of them dairy farmers. A questionnaire was mailed to all 418 farmers who were alive of the farmers originally participating in 1982. They were invited to an interview, spirometry, and blood sampling. Ninety-one per cent (380) of the farmers, 321 men and 59 women, responded to the questionnaire. The mean age was 56 years for the men and 55 years for the women. Of the group, 10% were smokers, 25% ex-smokers, and 65% had never smoked. The population estimate for asthma in the farmers was 8.9% in 1994 compared to 2% in 1982, and to 5.4%–6.6% in the general population in the region in 1982. Of the asthmatic subjects, one-third had positive RAST tests (radioallergosorbent tests). Almost 90% of the new onset asthma cases since 1982 had non-IgE-mediated asthma. Most of the IgE-mediated asthmatics had had symptoms for many years, while 70% of the non-IgE-mediated asthmatic farmers had no or only wheezing with colds 1982. Two new cases of hypersensitivity pneumonitis were identified, and 7.3% had experienced inhalation fever during the last 12 years. In general, individuals with asthma and chronic bronchitis who had left farming were in better health in 1994 as compared to 1982. In conclusion, farmers have an enhanced risk to develop asthma increasing with age. Asthma in farmers is often non-IgE-mediated.

2011-01-01

9

COPD and microalbuminuria: a 12-year follow-up study.  

PubMed

Chronic obstructive pulmonary disease (COPD), low lung function independent of diagnosis and markers of inflammation are all associated with increased morbidity and mortality. Microalbuminuria, reflecting endothelial dysfunction, could be a relevant inflammatory marker of potential systemic effects of COPD. We hypothesised that there was a positive association between microalbuminuria and mortality in individuals with COPD. We conducted a 12-year follow-up study of 3129 participants in the second survey of the Nord-Trøndelag Health Study (HUNT), Norway. At baseline, albuminuria was analysed in three urine samples and spirometry was performed. Among the participants, 136 had COPD and microalbuminuria, defined as a urinary albumin/creatinine ratio between 2.5 and 30.0 mg·mmol(-1). The main outcome measures were hazard ratio of all-cause mortality according to microalbuminuria. Compared to those with COPD without microalbuminuria, the adjusted hazard ratio for all-cause mortality in those with COPD and microalbuminuria was 1.54, 95% CI 1.16-2.04. This result was similar after excluding cardiovascular disease at baseline. Classifying COPD severity by Global Initiative for Chronic Obstructive Lung Disease, there was a positive association trend with increasing severity stages. Microalbuminuria is associated with all-cause mortality in individuals with COPD and could be a relevant tool in identification of patients with poor prognosis. PMID:24435009

Romundstad, Solfrid; Naustdal, Thor; Romundstad, Pål Richard; Sorger, Hanne; Langhammer, Arnulf

2014-04-01

10

Seven-year follow-up on lopinavir/ ritonavir monotherapy.  

PubMed

Previous studies of lopinavir/ritonavir (LPV/r) monotherapy have shown that over 70% of patients achieved HIV RNA levels <500 copies/mL over a follow-up period of 48 to 96 weeks, but the long-term durability is undetermined. Herein, the authors report 2 patients that started LPV/r monotherapy after virologic failure on an NNRTIbased regimen and have been successfully treated for greater than 7 years. Both patients demonstrated long-term control of viral replication over the course of treatment, although the first patient had 3 viral load blips and the second had 1 blip under 400 copies/mL. Both patients had increases in CD4+ lymphocyte counts. The first patient from 96 cells/microL to 378 cells/microL and the second patient from 71 cells/microL to 411 cells/microL. To the authors knowledge, these 2 cases represent the longest experience with LPV/r monotherapy and provide some measure of reassurance about the durability of LPV/r for control of HIV replication. PMID:19414830

Pierone, Gerald; Mieras, Jeffrey; Martin, Amber; Urban, Theresa

2009-01-01

11

Infantile Amnesia across the Years: A 2-Year Follow-Up of Children's Earliest Memories  

ERIC Educational Resources Information Center

Although infantile amnesia has been investigated for many years in adults, only recently has it been investigated in children. This study was a 2-year follow-up and extension of an earlier study. Children (4-13 years old) were asked initially and 2 years later for their earliest 3 memories. At follow-up, their age at the time of these memories…

Peterson, Carole; Warren, Kelly L.; Short, Megan M.

2011-01-01

12

Alberta Euthanasia Survey: 3-year follow-up.  

PubMed Central

OBJECTIVE: To determine whether the opinions of Alberta physicians about active euthanasia had changed and to assess the determinants of potential changes in opinion. DESIGN: Follow-up survey (mailed questionnaire) of physicians included in the 1991 Alberta Euthanasia Survey. SETTING: Alberta. PARTICIPANTS: Of the 1391 physicians who participated in the 1991 survey 1291 (93%) had indicated that they were willing to take part in a follow-up survey. A follow-up questionnaire was mailed in 1994 to 1146 physicians who could be traced through the 1994 Medical Directory of the provincial college of physicians and surgeons; 25 questionnaires were returned because they could not be delivered. OUTCOME MEASURES: Physicians' opinions about (a) the morality of active euthanasia, (b) changes in the law to permit active euthanasia and (c) the practice of legalized euthanasia. RESULTS: Of the 1121 physicians sent a follow-up questionnaire 866 (77%) returned it completed. The responses of these same 866 physicians in 1991 provided a basis for comparison. Of the 866, 360 (42%) stated in the 1994 survey that it is sometimes right to practise active euthanasia; a similar proportion (384 [44%]) gave this response in 1991. However, other opinions changed significantly. In 1991, 250 of the respondents (29%) indicated that they would practise active euthanasia if it were legalized, as compared with 128 (15%) in 1994 (p < 0.01). In 1991, 429 (50%) of the respondents thought that the law should be changed to permit active euthanasia, as compared with 316 (37%) in 1994 (p < 0.01). Religious activity was the most important characteristic associated with changes in opinion. Despite the decrease in support for the practice and legalization of active euthanasia between 1991 and 1994, in both surveys at least 70% of those who responded to this question indicated that active euthanasia, if it were legalized, should be performed only by physicians and should be taught at medical sites. CONCLUSION: Alberta physicians' support for the practice and legalization of active euthanasia decreased considerably between 1991 and 1994. However, most physicians remain in favour of restricting active euthanasia, if it were legalized, to the medical profession. These results suggest a need for caution and deliberation when changes in the law concerning active euthanasia are examined.

Verhoef, M J; Kinsella, T D

1996-01-01

13

Prenatal Aspirin and Acetaminophen: 7-Year Follow-up.  

National Technical Information Service (NTIS)

The study examined the long-term effects of prenatal exposure to aspirin and acetaminophen. Three types of outcomes were examined in 7-year old children: attentional parameters; IQ scores; and height, weight, and head circumference. The analyses addressed...

A. P. Streissguth H. M. Barr

1987-01-01

14

A 33Year Follow-up of Narcotics Addicts  

Microsoft Academic Search

Background: This study examined longitudinal pat- terns of heroin use, other substance use, health, mental health, employment, criminal involvement, and mortal- ity among heroin addicts. Methods: The sample was composed of 581 male heroin addicts admitted to the California Civil Addict Program (CAP) during the years 1962 through 1964; CAP was a compulsory drug treatment program for heroin- dependent criminal

Yih-Ing Hser; Valerie Hoffman; Christine E. Grella; M. Douglas Anglin

2001-01-01

15

Ten Year Follow-up Study of 65 Suicidal Adolescents  

PubMed Central

Introduction: This survey studies the 10 year psychosocial outcome of 65 adolescents admitted to the Nancy Children’s Hospital in 1994 after a suicide attempt. Method: survey conducted using a self-assessment questionnaire sent to adolescents and their parents. Results: The response rate was 55.4%. About seventy per cent (70.5%) of respondents stated they were happy in their affective lives 10 years after the reference attempt, almost 70% (67.6%) had a job, nearly three quarters (72.5%) considered that they were in good health and 59% felt happy. More than half (55%) had made a subsequent suicide attempt. Two patients committed suicide. The originality of this study lies in its methodology since it allows, through comparison of suicide attempters’ responses with medical data, a high level of under-declaration of repeated attempts to be detected (41.2%). Statistical study of the associations between the total number of repeated suicide attempts and demographic characteristics of the initial population nonetheless evidenced that patients with a history of suicide attempts and those with a history of early repeated attempts (within three months and/or the year) were significantly more likely to repeat their attempt within ten years. Conclusion: Most of the 34 patients traced seemed to have satisfactory personal and professional lives, in contrast to the high level of repeated suicide attempts. Repeated suicide attempts during adolescence appear to be one of the major risk factors in attempting suicide again within 10 years. This confirms the importance of preventive measures after a first suicide attempt.

Gehin, Anouk; Kabuth, Bernard; Pichene, Catherine; Vidailhet, Colette

2009-01-01

16

Project DARE: no effects at 10-year follow-up.  

PubMed

The present study examined the impact of Project DARE (Drug Abuse Resistance Education), a widespread drug-prevention program, 10 years after administration. A total of 1,002 individuals who in 6th grade had either received DARE or a standard drug-education curriculum, were reevaluated at age 20. Few differences were found between the 2 groups in terms of actual drug use, drug attitudes, or self-esteem, and in no case did the DARE group have a more successful outcome than the comparison group. Possible reasons why DARE remains so popular, despite the lack of documented efficacy, are offered. PMID:10450631

Lynam, D R; Milich, R; Zimmerman, R; Novak, S P; Logan, T K; Martin, C; Leukefeld, C; Clayton, R

1999-08-01

17

Results of an uncemented straight femoral shaft prosthesis after 9 years of follow-up  

Microsoft Academic Search

The first consecutive 250 implantations of an uncemented, proximally anchored straight femoral shaft prosthesis (BiCONTACT) in 236 patients are included in this prospective follow-up study. Average time of follow-up evaluation was 8.9 years (range, 7.4-10.7 years). At follow-up, 27 patients had died, and 2 could not be located. Seven patients underwent revision-2 for infection, 1 for recurrent dislocation, 2 for

C Eingartner; R Volkmann; E Winter; F Maurer; G Sauer; S Weller; K Weise

2000-01-01

18

A Follow-Up Study of Marines Two and a Half Years after Recruit Training.  

National Technical Information Service (NTIS)

This report describes a follow-up study of 228 Marines two and a half years after they received recruit training at MCRD, San Diego. A sample of Marines who began recruit training in October 1978 participated in a follow-up study. The subjects completed a...

I. G. Sarason R. W. Novaco B. R. Sarason

1981-01-01

19

Two-Year Follow-Up of Bibliotherapy and Individual Cognitive Therapy for Depressed Older Adults  

ERIC Educational Resources Information Center

This study examined the stability of treatment gains after receiving either cognitive bibliotherapy or individual cognitive psychotherapy for depression in older adults. A 2-year follow-up of 23 participants from Floyd, Scogin, McKendree-Smith, Floyd, and Rokke (2004) was conducted by comparing pre- and posttreatment scores with follow-up scores…

Floyd, Mark; Rohen, Noelle; Shackelford, Jodie A. M.; Hubbard, Karen L.; Parnell, Marsha B.; Scogin, Forrest; Coates, Adriana

2006-01-01

20

How persistent is ADHD? A controlled 10-year follow-up study of boys with ADHD  

Microsoft Academic Search

The main aim of this study was to examine the age-dependent persistence of attention-deficit hyperactivity disorder (ADHD) in boys transitioning from adolescence into early adulthood attending to different definitions of persistence. We conducted a 10-year follow-up study (mean follow-up time=11years) of 110 boys with ADHD and 105 non-ADHD controls. Both groups were 6–17years of age at ascertainment. ADHD was considered

Joseph Biederman; Carter R. Petty; Maggie Evans; Jacqueline Small; Stephen V. Faraone

2010-01-01

21

Effect of Rapid Maxillary Expansion on Nasal Airway Resistance: A One Year Follow-Up.  

National Technical Information Service (NTIS)

This thesis evaluated changes in nasal resistance to airflow in individuals undergoing rapid maxillary expansion, and to reevaluate the response at a one year follow-up. Nasal resistance measurements, assessed in four modes (natural state, anterior nares ...

D. V. Hartgerink

1986-01-01

22

Course and Outcome in Delusional Psychoses. A 4Year Re-Follow-Up  

Microsoft Academic Search

The purpose of the study was to examine the 4-year course and outcome in first-admitted patients with delusional psychoses, and to compare the findings with those of a 2-year follow-up. The index population comprised 88 patients. At follow-up one-fifth of the patients revealed positive psychotic symptoms, half of the patients had experienced psychotic relapse, and one-fourth had remitted fully. Compared

Per Jørgensen

1989-01-01

23

Predictors of ADHD Persistence in Girls at 5Year Follow-Up  

Microsoft Academic Search

Objective: The main aim of this study was to examine the age-dependent remission from ADHD in girls transitioning through childhood into adolescence and early adulthood. Method: We conducted a 5-year prospective follow-up study of 123 girls with ADHD and 106 non-ADHD control girls aged between 6 and 17 years at ascertainment. ADHD was considered persistent at follow-up if participants met

Eric Mick; Deirdre Byrne; Ronna Fried; Michael Monuteaux; Stephen V. Faraone; Joseph Biederman

2011-01-01

24

Conservative total Articular Replacement Arthroplasty: Minimum 20Year Follow-Up  

Microsoft Academic Search

\\u000a \\u000a Hip joint resurfacing is an attractive concept because it preserves rather than removes the femoral head and neck and may\\u000a provide better functioning. We report the first long-term follow-up on total hip resurfacing. A total of 445 patients (561\\u000a hips) were followed for a minimum of 20 years or until death; only 23 patients were lost to follow-up. Patients received

James W. Pritchett

25

Incidence of RBD and hallucination in patients affected by Parkinson's disease: 8-year follow-up  

Microsoft Academic Search

We describe the 8-years follow-up of 80 patients affected by idiopathic, L-dopa-responsive Parkinson's disease. All patients were evaluated at baseline and during the follow-up with visual evoked potential, P300 event related potentials and polysomnography. The patients and their relatives compiled sleep and hallucination questionnaires. Statistical analysis was performed to evaluate if visual abnormalities, abnormal P300 recordings or sleep disturbances were

M. Onofrj; A. Thomas; G. D'Andreamatteo; D. Iacono; A. L. Luciano; A. Di Rollo; R. Di Mascio; E. Ballone; A. Di Iorio

2002-01-01

26

The Preschool Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS) 6-Year Follow-Up  

ERIC Educational Resources Information Center

Objective: To describe the clinical course of attention-deficit/hyperactivity disorder (ADHD) symptom severity and diagnosis from ages 3 to 5 up to 9 to 12 years during a 6-year follow-up after the original Preschool ADHD Treatment Study (PATS). Method: A total of 207 participants (75% male) from the original PATS, assessed at baseline (mean age,…

Riddle, Mark A.; Yershova, Kseniya; Lazzaretto, Deborah; Paykina, Natalya; Yenokyan, Gayane; Greenhill, Laurence; Abikoff, Howard; Vitiello, Benedetto; Wigal, Tim; McCracken, James T.; Kollins, Scott H.; Murray, Desiree W.; Wigal, Sharon; Kastelic, Elizabeth; McGough, James J.; dosReis, Susan; Bauzo-Rosario, Audrey; Stehli, Annamarie; Posner, Kelly

2013-01-01

27

Predictors of ADHD Persistence in Girls at 5-Year Follow-Up  

ERIC Educational Resources Information Center

Objective: The main aim of this study was to examine the age-dependent remission from ADHD in girls transitioning through childhood into adolescence and early adulthood. Method: We conducted a 5-year prospective follow-up study of 123 girls with ADHD and 106 non-ADHD control girls aged between 6 and 17 years at ascertainment. ADHD was considered…

Mick, Eric; Byrne, Deirdre; Fried, Ronna; Monuteaux, Michael; Faraone, Stephen V.; Biederman, Joseph

2011-01-01

28

Results of three to 10 year follow up of balloon dilatation of the pulmonary valve  

PubMed Central

Background—The results of immediate and short term follow up of balloon dilatation of the pulmonary valve have been well documented, but there is limited information on long term follow up.?Objective—To evaluate the results of three to 10 year follow up of balloon dilatation of the pulmonary valve in children and adolescents.?Setting—Tertiary care centre/university hospital.?Design—Retrospective study.?Methods and results—85 patients (aged between 1 day and 20 years, mean (SD) 7.0 (6.4) years) underwent balloon dilatation of the pulmonary valve during an 11 year period ending August 1994. There was a resultant reduction in the peak to peak gradient from 87 (38) to 26 (22) mm Hg. Immediate surgical intervention was not required. Residual gradients of 29 (17) mm Hg were measured by catheterisation (n = 47) and echo Doppler (n = 82) at intermediate term follow up (two years). When individual results were scrutinised, nine of 82 patients had restenosis, defined as a peak gradient of 50 mm Hg or more. Seven of these patients underwent repeat balloon dilatation of the pulmonary valve: peak gradients were reduced from 89 (40) to 38 (20) mm Hg. Clinical evaluation and echo Doppler data of 80 patients showed that residual peak instantaneous Doppler gradients were 17 (15) mm Hg at long term follow up (three to 10 years, median seven), with evidence for late restenosis in one patient (1.3%). Surgical intervention was necessary to relieve fixed infundibular stenosis in three patients and supravalvar pulmonary stenosis in one. Repeat balloon dilatation was performed to relieve restenosis in two patients. Actuarial reintervention free rates at one, two, five, and 10 years were 94%, 89%, 88%, and 84%, respectively. Pulmonary valve regurgitation was noted in 70 of 80 patients at late follow up, but neither right ventricular dilatation nor paradoxical interventricular septal motion developed.?Conclusions—The results of late follow up of balloon dilatation of the pulmonary valve are excellent. Repeat balloon dilatation was performed in 11% of patients and surgical intervention for subvalvlar or supravalvar stenosis in 5%. Most patients had mild residual pulmonary regurgitation but right ventricular volume overload did not develop and surgical intervention was not required. Balloon dilatation is the treatment of choice in the management of moderate to severe stenosis of the pulmonary valve. Further follow up studies should be undertaken to evaluate the significance of residual pulmonary regurgitation.?? Keywords: balloon dilatation of the pulmonary valve;  pulmonary stenosis;  pulmonary regurgitation

Rao, P; Galal, O; Patnana, M; Buck, S; Wilson, A

1998-01-01

29

FACTORS ASSOCIATED WITH THE COURSE AND OUTCOME OF SCHIZOPHRENIA A MULTICENTRED FOLLOW-UP STUDY : RESULT OF FIVE YEAR FOLLOW-UP  

PubMed Central

SUMMARY This paper describes the results of a five year follow up study on factors associated with the course and outcome of schizophrenia conducted in 3 centers (Lucknow, Madras and Vellore) under the auspices of the Indian Council of Medical Research. 386 patients who satisfied well defined criteria of diagnosis and inclusion and exclusion criteria were studied. All patients were regularly followed up. 287 patients had complete follow up after 5 years. After 2 years, most of the active symptoms had subsided. At 5 year follow up, about 67% of the patients showed good outcome. Regular drug compliance, short duration of illness, absence of economic difficulties, absence of dangerous behaviour and delusions of presecution at intake; presence of agitation at intake; acute onset, absence of schizoid traits in personality, low level of education, rural background and lower age of onset were significantly related to good outcome. A combination of 8 factors could correctly predict the outcome in 80% of patients. The implications of the above findings are discussed.

Verghese, A.; Dube, K.C.; John, J.K.; Kumar, N.; Nandi, D.N.; Parhee, R.; Rajkumar, S.; Richard, J.; Menon, Sarada M.; Sethi, B.B.; Trivedi, J.K.

1990-01-01

30

Metal-on-metal total hip arthroplasty - five- to 11-year follow-up.  

PubMed

Metal-on-metal (MoM) total hip arthroplasty (THA) has been introduced in an attempt to reduce the wear rate and the consequent osteolysis around implants. The aim of this study was to present the intermediate to long-term clinical and radiological outcomes and to investigate the metal ion levels in the blood of patients who had undergone primary uncemented MoM THA in our institution. Between July 1997 and November 2003, 166 patients (193 hips), with a mean age of 50 years (range, 18-65 years), underwent primary MoM THA. Clinical data, radiographs, and blood samples were obtained at regular follow-up visits. Cobalt (Co), chromium (Cr), and molybdenum (Mo) ions were measured by inductively coupled plasma-mass spectrometry (ICP-MS) from the patient's whole blood. All patients were prospectively followed for a minimum of 5 years (mean, 7 years; range, 5-11 years). The mean Harris hip score (HHS) and the University of California at Los Angeles (UCLA) activity score at the latest follow-up was 88 ± 11 and 7 ± 1.8 points, respectively. Thirteen hips have been revised. Ten acetabular components had early failure, due to factory manufacturing problems. All other implants have been found stable, with no signs of aseptic loosening. The probability of survival at 11 years, if the hips that were revised due to manufacturing problems were excluded, was 98.4%. The Co and Cr metal ion levels, after increasing significantly during the first 4 to 5 years post-surgery, remained stable, with a tendency to decrease thereafter, but not significantly. During the same follow-up period, Mo ion levels remained stable. In this 5-to-11 year follow-up study of MoM THA patients, excellent survivorship, with low complications rates, was found. Results of longer follow-up studies are necessary to clarify the possible long-term effects of metal ion release. PMID:22035490

Nikolaou, Vassilios S; Petit, Alain; Debiparshad, Kevin; Huk, Olga L; Zukor, David J; Antoniou, John

2011-01-01

31

A 2-year follow-up study of discharged psychiatric patients with bipolar disorder.  

PubMed

This study investigated medication compliance, disease recurrence and the recovery of social function in discharged psychiatric patients with bipolar disorder. A 2-year follow-up was conducted on all patients with bipolar disorder, who were hospitalized in our psychiatric department between June 2010 and May 2011. Risk factors for recurrence were analyzed based on a self-designed questionnaire. Of the 252 patients in the study, 210 had complete information (83.3%) for the 2-year follow-up: 170 cases of bipolar I disorder and 40 cases of bipolar II disorder. The 1-year and 2-year full-compliance rates were 41.0% and 35.7%, respectively. The 1-year and 2-year recurrence rates were 42.4% and 61.0%, respectively. Statistically significant differences in rates were found between the bipolar subtypes for 1-year full compliance, 1-year non-compliance, 2-year recurrence, and 2-year readmission. Logistic regression identified different sets of independent variables that were risk factors for recurrence, and protective factors for recurrence at 1 year and 2 years after hospital discharge. The results of the follow-up indicated that the situation of patients with bipolar disorder after discharge is not optimistic, because of high recurrence rates, high non-compliance rates and low recovery rates. Clinical and social experts should pay more attention to the situation. PMID:24794029

Li, Chunyang; Chen, Chao; Qiu, Bin; Yang, Guang

2014-08-15

32

Orthodontic traction in a patient with cleidocranial dysplasia: 3 years of follow-up.  

PubMed

This case report describes the treatment and long-term follow-up care of a patient diagnosed with cleidocranial dysplasia who had multiple impacted permanent and supernumerary teeth. The aim of the treatment was to provide an adequate esthetic and functional reconstruction of the occlusion with good periodontal care. The patient was treated with a multidisciplinary therapeutic protocol including orthodontic and surgical procedures, and traction of 11 permanent teeth. The proposed objectives of good occlusion, normal function, healthy periodontium, and balanced profile were achieved, and the 3-year follow-up records showed stable results. PMID:24975005

Rocha, Roberto; Zasso, Manuela Batistella; Floriano, Gilberto; Derech, Carla; Ribeiro, Gerson Ulema; Locks, Arno; Ritter, Daltro

2014-07-01

33

The maintenance of psychotherapy skill acquisition: a two-year follow-up.  

PubMed

A two-year follow-up study investigated changes in interview behaviour of 11 therapists who had previously been trained in the conversational model of psychotherapy by a combined videotaped microteaching and supervision package. Results generally showed the acquired skills had been well maintained. However, there was a large increase in the giving of information and explanation, a behaviour explicitly discouraged within the conversational model. In addition, the response to verbal cues, a positive model behaviour, decreased over the follow-up period. PMID:1954188

Moss, S; Margison, F; Godbert, K

1991-09-01

34

Clinical treatment of a ruptured temporomandibular joint disc: morphological changes at 5-year follow-up.  

PubMed

Osteoarthrosis is a disease that affects the temporomandibular joint (TMJ). This case report chronicles the diagnosis and treatment of a patient for whom this pathological condition was accompanied by a rupture of the articular disc. The patient presented with loud sounds in the left TMJ and an irregular mandibular occlusal plane due to condylar intrusion in the glenoid fossa on the ipsilateral side. A noninvasive treatment was selected. A 4-month follow-up revealed remission of the articular sounds, and tissue regeneration was noted. These improvements remained visible at 5-year follow-up. PMID:24598507

Cardinal, Lucas; Porto, Felipe; Agarwal, Sachin; Grossman, Eduardo

2014-01-01

35

Austin bunionectomy using single screw fixation: five-year versus 18-month follow-up findings.  

PubMed

The authors present a follow-up of the Austin bunionectomy using a single 2.7-mm American Society of Internal Fixation (ASIF) screw. At a mean 5-year follow-up, 45 feet in 32 patients were evaluated with information from clinical examination, radiographic data, and responses to a patient questionnaire. When compared to the 18-month follow-up, good reduction of the intermetatarsal and the hallux abductus angle were maintained. Clinical findings, including the first metatarsophalangeal joint range of motion and hallux purchase power, remained acceptable, and a small number of new transfer lesions were noted. Patient satisfaction with appearance and overall satisfaction with the procedure remained excellent-to-good in 96% of the procedures. PMID:8807487

Goforth, W P; Martin, J E; Domrose, D S; Sligh, T S

1996-01-01

36

Six years of following up a glomus jugulare tumor - a case report.  

PubMed

This case report followed up a patient for six years after she had been successfully treated by embolization and gamma knife surgery, while a complete surgical resection was contraindicated because of the high risk of possible mortality outcome. A development of internal hydrocephalus in a subacute postoperative period as a probable postoperative complication related to gamma knife surgery was noted. PMID:22634920

Stenc Bradvica, Ivanka; Jan?uljak, Davor; Butkovi?-Soldo, Silva; He?imovi?, Ivan

2012-02-01

37

Mortality of patients with mood disorders: follow-up over 34–38 years  

Microsoft Academic Search

Background: All follow-up studies of causes of death in affective disordered patients have found they have markedly elevated suicide rates and a less reproducible increased mortality from other causes. The reported rates by gender, disorder type and treatment are more variable. Methods: Hospitalised affective disordered patients (n=406) were followed prospectively for 22 years or more. Later, mortality was assessed for

F Angst; H. H Stassen; P. J Clayton; J Angst

2002-01-01

38

Pre-Placement Anxiety among Foundation-Year MSW Students: A Follow-up Study  

ERIC Educational Resources Information Center

This Field Note presents a follow-up to a pilot study that explored pre-field placement anxiety for 1st-year MSW students. Previous studies report that students experience significant anxiety as they anticipate their field placement, and research indicates that anxiety has the potential to affect learning. A sample of 204 students reported…

Rosenthal Gelman, Caroline; Lloyd, Chrishana M.

2008-01-01

39

Spontaneous necrosis of parathyroid adenoma: biochemical and imaging follow-up for two years  

PubMed Central

We report a patient with a biochemically and radiologically confirmed parathyroid adenoma, which underwent spontaneous resolution by necrosis. The patient was followed-up over the subsequent two years during which time the tumour and hypercalcaemia recurred. Sequential radiological and biochemical changes at the time of diagnosis, spontaneous necrosis and recurrence are documented fully.???Keywords: hyperparathyroidism; hypocalcaemia; apoplexy

Chan, W; Chow, C; King, A; Yeung, V; Li, J; So, W; Cockram, C

2000-01-01

40

Sex Stereotypes and School Science: A Three Year Follow-Up.  

ERIC Educational Resources Information Center

Presents follow-up to Girls into Science and Technology Project and examines development over three-year period of children's sex stereotypes and their attitudes toward and achievements in science. Concludes that, although some links were evident, sex stereotypes were only weakly related to children's achievements in, choice of, and attitudes…

Kelly, Alison

1988-01-01

41

Enhanced physical therapy for arm function after stroke: a one year follow up study  

Microsoft Academic Search

Ninety seven patients with stroke who had participated in a randomised trial of conventional physical therapy nu an enhanced therapy for arm function were followed up at one year. Despite the emphasis of the enhanced therapy approach on continued use of the arm in everyday life, the advantage seen for some patients with enhanced therapy at six months after stroke

A Sunderland; D Fletcher; L Bradley; D Tinson; R L Hewer; D T Wade

1994-01-01

42

The Sexual Adjustment of Coronary Bypass Surgery Patients: A 4-Year Follow-Up.  

ERIC Educational Resources Information Center

Measured the sexual adjustment of 14 individuals before coronary bypass surgery and both four months and four years afterwards. Results showed that sexual adjustment worsened with the onset of symptomatic coronary artery disease and did not improve at either follow-up interval. (LLL)

Thurer, Shari; Thurer, Robert L.

1983-01-01

43

Nursing Education Follow-Up Study--1974 R.Ns. a Year After Graduation.  

ERIC Educational Resources Information Center

A group of 41 registered nursing graduates of the 1974 class at Bakersfield College was surveyed in the summer of 1974 as part of a nursing education follow-up study. In the summer of 1975, the same group was surveyed again in order to compare the perceptions and aspirations reported by the graduates one year after graduation with those reported…

Scott, David C.

44

Children of parents with unipolar depression: A controlled 1-year follow-up  

Microsoft Academic Search

An earlier cross sectional study indicated that children's health and adjustment is at risk when their parents are depressed. Here, we report the associated longitudinal changes in children and families when parental depression either remits or continues. Comparisons are made among three groups established at a 1 year follow up: (a) previously depressed parents whose symptoms have remitted (N=34 remitted

Andrew G. Billings; Rudolf H. Moos

1986-01-01

45

Nevus Depigmentosus Treated with Suction Blister Grafting: Follow-up After 10 Years  

PubMed Central

Nevus depigmentosus is a congenital hypomelanotic condition for which no effective treatments are available. The hypopigmentation is permanent and enlarges in proportion with growth in the person. Here, I report a patient of nevus depigmentosus on whom we performed suction blister grafting and the resultant pigmentation was satisfactory even at a follow-up after 10 years.

Kar, Bikash Ranjan

2013-01-01

46

Infantile-Onset Diabetes Mellitus: A 1Year Follow-up Study  

Microsoft Academic Search

This study evaluates the clinical profiles and outcomes of children with infantile-onset diabetes mellitus (IODM) (onset at <1 year). Twelve infants with IODM presenting to our hospital from January 2003 to December 2007 are analyzed. All undergo thorough history, clinical examination, and investigations and are managed as per hospital-approved protocol and periodically followed up. Of 12 infants (3 boys and

Ramaswamy Ganesh; Ravindrakumar Arvindkumar; Thiruvengadam Vasanthi

2009-01-01

47

Social Effectiveness Therapy for Children: Three-Year Follow-Up  

ERIC Educational Resources Information Center

This study reports the results of a 3-year follow-up assessment of children and adolescents diagnosed with social anxiety disorder (social phobia) and treated with Social Effectiveness Therapy for Children (SET-C), a comprehensive behavioral treatment program combining social skills training, peer generalization, and individualized exposure. Among…

Beidel, Deborah C.; Turner, Samuel M.; Young, Brennan; Paulson, Autumn

2005-01-01

48

Magnitude of end-stage renal disease in IDDM: A 35 year follow-up study  

Microsoft Academic Search

Magnitude of end-stage renal disease in IDDM: A 35 year follow-up study. Significant improvements were made during the last two decades in the treatment of IDDM patients. To assess the risk of ESRD in a population that was exposed to these improvements, we determined the cumulative incidence of ESRD in a cohort of 142 white patients who were aged less

Martin Krolewski; Paul W Eggers; James H Warram

1996-01-01

49

Psychopathy and Offending From Adolescence to Adulthood: A 10-Year Follow-Up  

ERIC Educational Resources Information Center

This study examined the predictive validity of the Hare Psychopathy Checklist: Youth Version (PCL:YV; A. E. Forth, D. S. Kosson, & R. D. Hare, 2003) from adolescence to early adulthood. The authors coded the PCL:YV using file information and collected criminal record information over a 10-year follow-up period on 157 boys, ages 12 through 18,…

Gretton, Heather M.; Hare, Robert D.; Catchpole, Rosalind E. H.

2004-01-01

50

Ten Years Later: A Follow-Up Study of Professors Still Working after Age 70  

ERIC Educational Resources Information Center

Little is known about the impact of the end of mandatory retirement on professors over the long term. This follow-up study investigated the ten-year experience of professors who chose not to retire from a major research university after the elimination of the age 70 mandatory retirement in 1994. The initial interview study was conducted in 1998…

Dorfman, Lorraine T.

2009-01-01

51

Battered Women's Process of Leaving: A 2-Year Follow-Up  

ERIC Educational Resources Information Center

This study is a follow-up investigation of the career and life experiences of battered women two years after shelter exit. Using consensual qualitative research, we interviewed 6 women from our original sample of 13 regarding their career and life adjustments and future aspirations. Results indicated that participants generally reported both…

Brown, Chris; Trangsrud, Heather B.; Linnemeyer, Rachel M.

2009-01-01

52

Offending Behaviours of Child and Adolescent Firesetters over a 10-Year Follow-Up  

ERIC Educational Resources Information Center

Background: To assess the postintervention arson recidivism and other offending rates of a group of 182 firesetting children and adolescents referred to the New Zealand Fire Awareness and Intervention Program (FAIP) over a follow-up period of 10 years. To investigate predictors of offending behaviour as well as variables associated with previous…

Lambie, Ian; Ioane, Julia; Randell, Isabel; Seymour, Fred

2013-01-01

53

Perspective Transformation over Time: A 2-Year Follow-up Study of HIV-Positive Adults.  

ERIC Educational Resources Information Center

A follow-up study of 14 of 18 HIV-positive adults showed that their perspective transformation had been maintained 2 years later. Their meaning schemes changed to include a future-oriented perspective, greater attention to self-care, and integration of their HIV-positive status into their self-definition. (SK)

Courtenay, Bradley C.; Merriam, Sharan; Reeves, Patricia; Baumgartner, Lisa

2000-01-01

54

Transvaginal cystocele repair using a tension-free polypropylene mesh: more than 5 years of follow-up  

Microsoft Academic Search

ObjectivesProspective randomized controlled trials, with 2 yearsfollow-up, seem to lean in favour of anterior repair using synthetic mesh. The goal of this study was to report on long-term (>5 years) follow-up.

Vincent Letouzey; Xavier Deffieux; Amélie Gervaise; Grégoire Mercier; Hervé Fernandez; Renaud de Tayrac

2010-01-01

55

Four-year follow-up of endoscopic gastroplication for the treatment of gastroesophageal reflux disease  

PubMed Central

AIM: To evaluate the long-term effect of Endocinch treatment for gastroesophageal reflux disease (GERD). METHODS: After unblinding and crossover, 50 patients (32 males, 18 females; mean age 46 years) with pH-proven chronic GERD were recruited from an initial randomized, placebo-controlled, single-center study, and included in the present prospective open-label follow-up study. Initially, three gastroplications using the Endocinch device were placed under deep sedation in a standardized manner. Optional retreatment was offered in the first year with 1 or 2 extra gastroplications. At baseline, 3 mo after (re) treatment and yearly proton pump inhibitor (PPI) use, GERD symptoms, quality of life (QoL) scores, adverse events and treatment failures (defined as: patients using > 50% of their baseline PPI dose or receiving alternative antireflux therapy) were assessed. Intention-to-treat analysis was performed. RESULTS: Median follow-up was 48 mo [interquartile range (IQR): 38-52]. Three patients were lost to follow-up. In 44% of patients retreatment was done after a median of 4 mo (IQR: 3-8). No serious adverse events occurred. At the end of follow-up, symptom scores and 4 out of 6 QoL subscales were improved (all P < 0.01 compared to baseline). However, 80% of patients required PPIs for their GERD symptoms. Ultimately, 64% of patients were classified as treatment failures. In 60% a post-procedural endoscopy was carried out, of which in 16% reflux esophagitis was diagnosed. CONCLUSION: In the 4-year follow-up period, the subset of GERD patients that benefit from endoscopic gastroplication kept declining gradually, nearly half opted for retreatment and 80% required PPIs eventually.

Schwartz, Matthijs P; Schreinemakers, J Rieneke C; Smout, Andre J P M

2013-01-01

56

Appalachian coal miner mortality study: a 14-year follow-up  

SciTech Connect

From 1963 to 1965, the U.S. Public Health Service examined 3,726 underground Appalachian bituminous coal miners who were living in 1962. Their vital status was verified on January 1, 1973 (10 years of follow-up) and again on January 1, 1976 (14 years of follow-up). Mortality was studied after 10 years and results were published by Ortmeyer (1974) and Costello (1974, 1975). The results of a study of the mortality after 14 years are the subject of this report. The cause of death was determined from the underlying cause recorded on the death certificate. Death from all causes, ischemic heart disease, non-malignant respiratory disease (NMRD), cancer of the trachea, bronchus, and lung, digestive cancer, and accidents were studied.

Amandus, H.

1982-06-08

57

On the course of low back pain in general practice: a one year follow up study  

PubMed Central

OBJECTIVES—Knowledge on the clinical course of low back pain presented in general practice is poor. Preceding studies offer a fragmentary view only, whereas further knowledge is important to enable the assessment of the prognosis. The object of this study is to investigate the course of low back pain presented in general practice to enable the assessment of the prognosis.?METHODS—A one year follow up study on the clinical course of low back pain in consecutive cases receiving usual care in general practice. During a period of two years 15 general practitioners from Amsterdam and surrounding areas included consecutive patients with both chronic and recent onset low back pain. After the initial visit, each patient was monitored for a period of 12 months. The follow up consisted of monthly postal questionnaires on the course of the low back pain and the related disability.?RESULTS—A total of 443 of 605 patients identified were included in the follow up, which was fully completed by 269 patients. In general, patients with less serious low back pain participated less often or did not complete the follow up. At 12 weeks 35% and at the end of the follow up 10% of the population, respectively, still suffered from low back pain. Both the pain and the disability seemed to diminish quickly after the initial visit, and both seemed to stabilise at a lower level if the low back pain did not disappear completely. About three of four patients, whose pain disappeared before the end of the follow up, endured one or more relapses within a year. The median time to a relapse was about seven weeks, and its median duration about six weeks. Both the pain and the disability turned out to be less severe during relapses. The median time to recovery for patients whose low back pain developed more than seven weeks before the initial visit, was four weeks longer than for patients with more recently developed low back pain at the initial visit.?CONCLUSIONS—The clinical course of low back pain presented in general practice, for the most patients, clearly is less favourable than expected. It takes more than just a few weeks to recover, and relapses occur within a year in most cases. Fortunately, both the pain and the disability quickly diminish, even if the low back pain does not resolve within a few weeks.?? Keywords: backache; prognosis; follow up study; general practice

van den Hoogen, H. J M; Koes, B.; van Eijk, J. T. M; Bouter, L.; Deville, W.

1998-01-01

58

One-Year Follow-Up in Stroke Patients Discharged from Rehabilitation Hospital  

Microsoft Academic Search

This study was designed to evaluate functional status at a 1-year follow-up in consecutive first-stroke patients after discharge from rehabilitation hospital and to identify reliable prognostic factors associated with changes in their abilities. Functional evaluation was made of consecutive patients 1 year after discharge to their own homes. Two multiple logistic regressions (forward stepwise) were performed using both improvement and

Stefano Paolucci; Maria Grazia Grasso; Gabriella Antonucci; Elio Troisi; Daniela Morelli; Paola Coiro; Maura Bragoni

2000-01-01

59

Ten-year follow-up of an anatomical hydroxyapatite-coated total hip prosthesis  

Microsoft Academic Search

We report our results after ten year follow-up of 107 consecutive ABG-I hip prostheses implanted between June 1990 and December 1992: Only 84 prostheses were still in the study after ten years, but only six patients had undergone surgical revision. We can consider our clinical outcomes as excellent, with a whole-implant survival rate greater than 96%, a mean Merle D’Aubigne

V. Canales Cortés; J. J. Panisello Sebastiá; A. Herrera Rodríguez; A. Peguero Bona; A. Martínez Martín; L. Herrero Barcos; L. García-Dihinx

2006-01-01

60

Developing COPD: a 25 year follow up study of the general population  

PubMed Central

Background Smokers are more prone to develop chronic obstructive pulmonary disease (COPD) than non?smokers, but this finding comes from studies spanning 10?years or less. The aim of this study was to determine the 25?year absolute risk of developing COPD in men and women from the general population. Methods As part of the Copenhagen City Heart Study, 8045 men and women aged 30–60?years with normal lung function at baseline were followed for 25?years. Lung function measurements were collected and mortality from COPD during the 25?year observation period was analysed. Results The percentage of men with normal lung function ranged from 96% of never smokers to 59% of continuous smokers; for women the proportions were 91% and 69%, respectively. The 25?year incidence of moderate and severe COPD was 20.7% and 3.6%, respectively, with no apparent difference between men and women. Smoking cessation, especially early in the follow up period, decreased the risk of developing COPD substantially compared with continuous smoking. During the follow up period there were 2912 deaths, 109 of which were from COPD. 92% of the COPD deaths occurred in subjects who were current smokers at the beginning of the follow up period. Conclusion The absolute risk of developing COPD among continuous smokers is at least 25%, which is larger than was previously estimated.

L?kke, A; Lange, P; Scharling, H; Fabricius, P; Vestbo, J

2006-01-01

61

Weight loss and health-related quality of life: results at 1-year follow-up.  

PubMed

To evaluate the 1-year results of treatment-induced weight loss on health-related quality of life (HRQL), 32 mildly to moderately overweight persons who participated in a 13-week weight loss program completed the Medical Outcomes Study Short Form-36 Health Survey (SF-36) at baseline, immediately after the program, and at 1-year follow-up. At 1 year, 65.6% of participants maintained at least some weight loss. The improvements on HRQL observed immediately after treatment on the physical functioning, role-physical, general health, vitality, and mental health scales of the SF-36 were maintained only on the general health and vitality scales at 1 year. There were no significant differences between weight maintainers and weight regainers on change from baseline to 1-year follow-up on HRQL. Our findings suggest that treatment-induced weight loss among mildly to moderately overweight persons improves HRQL and that at least some of these benefits are maintained at 1-year follow-up regardless of whether the weight loss is maintained. PMID:15000957

Fontaine, Kevin R; Barofsky, Ivan; Bartlett, Susan J; Franckowiak, Shawn C; Andersen, Ross E

2004-01-01

62

20-year prospective follow-up study of specialized treatment for adolescents who offended sexually.  

PubMed

Most follow-up investigations of the effectiveness of specialized treatment for adolescents who have offended sexually have not included a comparison group. Furthermore, the average length of most previous studies is approximately 5 years. This investigation is a 10-year extension of our prospective, 10-year follow-up study of specialized treatment (Worling & Curwen, 2000). Recidivism data (criminal charges) were collected from a national database for 148 adolescents who had offended sexually. Adolescents were between 12 and 19 years of age (M = 15.5; SD = 1.5) at assessment, and the follow-up interval spanned from 12 to 20 years (M = 16.23; SD = 2.02). Relative to the comparison group (n = 90), adolescents who participated in specialized treatment (n = 58) were significantly less likely to receive subsequent charges for sexual, nonsexual violent, and nonviolent crimes. These data add to the growing body of research supporting the effectiveness of specialized treatment for individuals who have offended sexually. PMID:19937708

Worling, James R; Litteljohn, Ariel; Bookalam, David

2010-01-01

63

Endoscopic stent therapy in patients with chronic pancreatitis: A 5-year follow-up study  

PubMed Central

AIM: This study analyzed clinical long-term outcomes after endoscopic therapy, including the incidence and treatment of relapse. METHODS: This study included 19 consecutive patients (12 male, 7 female, median age 54 years) with obstructive chronic pancreatitis who were admitted to the 2nd Medical Department of the Technical University of Munich. All patients presented severe chronic pancreatitis (stage III°) according to the Cambridge classification. The majority of the patients suffered intermittent pain attacks. 6 of 19 patients had strictures of the pancreatic duct; 13 of 19 patients had strictures and stones. The first endoscopic retrograde pancreatography (ERP) included an endoscopic sphincterotomy, dilatation of the pancreatic duct, and stent placement. The first control ERP was performed 4 wk after the initial intervention, and the subsequent control ERP was performed after 3 mo to re-evaluate the clinical and morphological conditions. Clinical follow-up was performed annually to document the course of pain and the management of relapse. The course of pain was assessed by a pain scale from 0 to 10. The date and choice of the therapeutic procedure were documented in case of relapse. RESULTS: Initial endoscopic intervention was successfully completed in 17 of 19 patients. All 17 patients reported partial or complete pain relief after endoscopic intervention. Endoscopic therapy failed in 2 patients. Both patients were excluded from further analysis. One failed patient underwent surgery, and the other patient was treated conservatively with pain medication. Seventeen of 19 patients were followed after the successful completion of endoscopic stent therapy. Three of 17 patients were lost to follow-up. One patient was not available for interviews after the 1st year of follow-up. Two patients died during the 3rd year of follow-up. In both patients chronic pancreatitis was excluded as the cause of death. One patient died of myocardial infarction, and one patient succumbed to pneumonia. All three patients were excluded from follow-up analysis. Follow-up was successfully completed in 14 of 17 patients. 4 patients at time point 3, 2 patients at time point 4, 3 patients at time point 5 and 2 patients at time point 6 and time point 7 used continuous pain medication after endoscopic therapy. No relapse occurred in 57% (8/14) of patients. All 8 patients exhibited significantly reduced or no pain complaints during the 5-year follow-up. Seven of 8 patients were completely pain free 5 years after endoscopic therapy. Only 1 patient reported continuous moderate pain. In contrast, 7 relapses occurred in 6 of the 14 patients. Two relapses were observed during the 1st year, 2 relapses occurred during the 2nd year, one relapse was observed during the 3rd year, one relapse occurred during the 4th year, and one relapse occurred during the 5th follow-up year. Four of these six patients received conservative treatment with endoscopic therapy or analgesics. Relapse was conservatively treated using repeated stent therapy in 2 patients. Analgesic treatment was successful in the other 2 patients. CONCLUSION: 57% of patients exhibited long-term benefits after endoscopic therapy. Therefore, endoscopic therapy should be the treatment of choice in patients being inoperable or refusing surgical treatment.

Weber, Andreas; Schneider, Jochen; Neu, Bruno; Meining, Alexander; Born, Peter; von Delius, Stefan; Bajbouj, Monther; Schmid, Roland M; Algul, Hana; Prinz, Christian

2013-01-01

64

Examining Whether Lung Screening Changes Risk Perceptions: NLST Participants at 1-year Follow-up  

PubMed Central

Purpose The National Lung Screening Trial (NLST) Research Team reported reduced lung cancer mortality among current and former smokers with a minimum 30-pack/year history, screened with spiral CT scans compared with chest x-ray. The objectives of this study are to examine, at one-year follow-up: 1) risk perceptions of lung cancer and smoking related diseases and behavior change determinants, 2) whether changes in risk perceptions differ by baseline screening result; and 3) whether changes in risk perceptions affect smoking behavior. Methods A 25-item risk perceptions sub-study questionnaire was administered to a subset of participants at 8 American College of Radiology Imaging Network (ACRIN)/NLST sites, prior to initial and one-year follow-up screens. Items assessed risk perceptions of lung cancer and smoking related diseases, cognitive and emotional determinants of behavior change, and knowledge of smoking risks. Results Among 430 NLST participants (M age=61.0, 55.6% male, 91.9% white), half were current smokers at baseline. Overall, risk perceptions, and associated cognitive and emotional determinants of behavior change, did not change significantly from prescreen trial enrollment to 1 year follow-up and did not significantly differ by screening test result. Changes in risk perceptions were not associated with smoking status changes (9.7% quitting, 6.6% relapse) at one-year follow-up. Conclusions Lung screening did not change participants’ risk perceptions for lung cancer or smoking related disease. A negative screening test, the most common result of screening, did not appear to decrease risk perceptions nor provide false reassurance to smokers.

Park, Elyse R.; Gareen, Ilana F.; Jain, Amanda; Ostroff, Jamie S.; Duan, Fenghai; Sicks, JoRean D.; Rakowski, Bill; Diefenbach, Michael; Rigotti, Nancy A.

2012-01-01

65

Operative survival and 40 year follow up of surgical repair of aortic coarctation.  

PubMed Central

OBJECTIVE--To study early and late mortality after surgical correction of coarctation of the aorta. DESIGN--Data on 223 patients operated on at the Westminster Hospital, London, between 1946 and 1981, were collected and updated by questionnaire. PARTICIPANTS--All 223 patients recorded as undergoing operation for aortic coarctation up to the end of 1981. Fifteen of 197 survivors were lost to follow up; most of them were patients from overseas. OUTCOME AND RESULTS--The early mortality (within one month of operation) was 12% overall, 2.6% for elective surgery, and 0% for the 77 patients undergoing surgery since 1968. Survivors were followed up for a total of 3288 patient years; in 27 follow up lasted more than 30 years. In a few it reached 40 years. Twenty two patients died during this period, 18 from causes that could be attributed to coarctation or its repair. Mortality was highest more than 20 years after the operation. CONCLUSION--Repair increased life expectancy in patients with aortic coarctation. Late problems caused by persistent hypertension or recoarctation became apparent in long term survivors. The increased risk of late mortality associated with the duration of preoperative hypertension was not statistically significant. There were no deaths from cerebrovascular accidents. (In an earlier necropsy series cerebrovascular accidents accounted for 11.8% of deaths.) The incidence of deaths from aneurysms resembled that in the earlier necropsy series.

Bobby, J J; Emami, J M; Farmer, R D; Newman, C G

1991-01-01

66

Cognitive behavioural therapy for obesity: one-year follow-up in a clinical setting.  

PubMed

Cognitive behavioural therapy (CBT) is the most comprehensive means of medically treating obesity, but only few data have so far been published concerning its long-term effectiveness. We here report our experience of 1068 consecutive patients (868 females) treated with CBT at a university-based obesity centre. The patients were enrolled into three different programmes: a 14-week LEARN programme (672 patients), a 16-week MOB programme for the morbidly obese (259 patients), or a 20-week BINGE programme for subjects affected by binge eating (137 patients). Eighty-five percent of the subjects completed the weekly programmes. The percentage of patients attending the scheduled control visits during the 1-year follow-up gradually decreased, being very low in the BINGE group (10%). The percentage weight loss was an average of 6% during the weekly courses, being higher in the MOB programme; by the end of the weekly sessions, it exceeded 10% of initial body weight in 22% of cases and increased to 36% during the follow-up. The cumulative probability of follow-up was higher among the patients undergoing the MOB and LEARN programmes than among the BINGE patients (p < 0.0001), and decreased with the increasing severity of obesity. Female gender and a weight loss of > 10% i.b.w. increased compliance to follow-up. The study further demonstrates the difficulty of achieving compliance to chronic management of obesity and the critical role of binge eating disorder in the medium-term treatment of obesity. Strategies are needed to improve adherence to a follow-up protocol. PMID:14649781

Melchionda, N; Besteghi, L; Di Domizio, S; Pasqui, F; Nuccitelli, C; Migliorini, S; Baraldi, L; Natale, S; Manini, R; Bellini, M; Belsito, C; Forlani, G; Marchesini, G

2003-09-01

67

Otitis media at Canyon Day, Ariz. A 16-year follow-up in Apache Indians.  

PubMed

A 16-year follow-up survey of native Americans living in Canyon Day, Ariz, did not show improvement in the 9.3% rate of clinically significant otitis media. However, the manifestations were more benign, especially in children, and included the spectrum of otitis media. A genetically determined eustachian tube difference may explain the high rate of occurrence of otitis media in these Apache Indians. Improvements in living conditions and health care may explain the change to less severe manifestations. PMID:4026678

Todd, N W; Bowman, C A

1985-09-01

68

Proliferative retinopathy predicts nephropathy: a 25-year follow-up study of type 1 diabetic patients  

Microsoft Academic Search

We wanted to examine proliferative retinopathy as a marker of incident nephropathy in a 25-year follow-up study of a population-based\\u000a cohort of Danish type 1 diabetic patients and to examine cross-sectional associations between nephropathy and retinopathy\\u000a in long-term surviving patients of the same cohort. All type 1 diabetic patients from Fyn County, Denmark, were identified\\u000a as of 1 July 1973.

Charlotte Karlberg; Christine Falk; Anders Green; Anne Katrin Sjølie; Jakob Grauslund

69

Sudden Sensorineural Hearing Loss Increases the Risk of Stroke A 5Year Follow-Up Study  

Microsoft Academic Search

Background and Purpose—No previous study has investigated the incidence or risk of cerebrovascular diseases developing after the sudden sensorineural hearing loss (SSNHL). This study sets out to estimate the risk of stroke development among SSNHL patients during a 5e-year follow-up period after hospitalization for acute episodes of SSNHL. Methods—Our study design features a study cohort and a comparison cohort. The

Herng-Ching Lin; Pin-Zhir Chao; Hsin-Chien Lee

2010-01-01

70

Arthroscopic Removal of Calcium Deposits of the Rotator Cuff: A 7-year Follow-up  

Microsoft Academic Search

Background: Calcium deposits within the tendons of the rotator cuff are common and usually asymptomatic. Symptomatic cases that do not respond to nonoperative measures need removal of the calcium deposits.Purpose: In this study, the results of arthroscopic removal of the calcium deposits within the rotator cuff, without rotator cuff repair, are evaluated after a minimum 7-year follow-up. This may help

Mohamed Taha El Shewy

2011-01-01

71

GM2 gangliosidosis (Sandhoff's disease): two year follow-up by MRI  

Microsoft Academic Search

Two children with GM-2 gangliosidosis type 0 (Sandhoff's disease) followed up by MRI at 1.5 Tesla for 1.8 years are reported. One was presymptomatic at the first MRI examination. As her neurological status deteriorated, MRI showed low signal in bilaterally, on T2-weighted images the white matter with involvement of the optic radiations. In the second, MRI correlated well with the

W. Koelfen; M. Freund; W. Jaschke; S. Koenig; C. Schultze

1994-01-01

72

Shock-wave therapy for tennis and golfer’s elbow – 1 year follow-up  

Microsoft Academic Search

Thirty patients with chronic medial epicondylitis were treated with low-energy shock waves. They received 500 impulses of\\u000a 0.08 mJ\\/mm2 three times at weekly intervals. At 1 year follow-up examinations were performed. According to the Verhaar criteria, only\\u000a seven patients reached excellent or good results. In eight cases a fair outcome was recorded, and in 14 patients the outcome\\u000a was poor.

O. Krischek; C. Hopf; B. Nafe; J.-D. Rompe

1999-01-01

73

Baseline predictors of three types of antiretroviral therapy (ART) adherence: A 2-year follow-up  

Microsoft Academic Search

The purposes of the study were to measure adherence with antiretroviral therapy to dose, schedule, and dietary instructions in a sample of patients with HIV infection in Stockholm, Sweden, over a 2-year period and identify baseline predictors of the three types of adherence. The study cohort consists of 144 patients who completed at least six out of seven follow-up self-reported

L. Nilsson Schönnesson; P. M. Diamond; M. W. Ross; M. Williams; G. Bratt

2006-01-01

74

Confabulation and Delusional Misidentification: A Four Year Follow-Up Study  

Microsoft Academic Search

We describe a patient, AZ, who showed, in addition to an amnesic syndrome which eventually improved, longstanding confabulation and delusional misidentification following bilateral frontal and right temporal post-traumatic lesions. Confabulation appeared in personal recollections and on long-term verbal memory testing. Misidentification concerned mainly his wife and house. During the four year follow-up AZ's confabulation progressively shrinked so as to become

Flavia Mattioli; Antonio Miozzo; Luigi A. Vignolo

1999-01-01

75

Febrile Convulsions in 220 Children – Neurological Sequelae at 12 Years Follow-Up  

Microsoft Academic Search

We report a 12-year follow-up study of children with febrile convulsions (FCs). The National General Practice Study of Epilepsy (NGPSE) is a large prospective community-based cohort study of 1,195 patients of all ages from first presentation with an identified seizure. Two hundred and twenty children with a first febrile convulsion were identified from the above study between 1984 and 1987.

Bridget K. MacDonald; Anthony L. Johnson; Josemir W. A. S. Sander; Simon D. Shorvon

1999-01-01

76

Outcomes of microfracture for traumatic chondral defects of the knee: Average 11-year follow-up  

Microsoft Academic Search

Purpose: In this study, we measured functional outcomes of patients treated arthroscopically with microfracture for full-thickness traumatic defects of the knee. Type of Study: A case series of patients with 7 to 17 yearsfollow-up. Methods: Between 1981 and 1991, a total of 72 patients (75 knees) met the following inclusion criteria: (1) traumatic full-thickness chondral defect, (2) no meniscus

J. Richard Steadman; Karen K. Briggs; Juan J. Rodrigo; Mininder S. Kocher; Thomas J. Gill; William G. Rodkey

2003-01-01

77

The Tessier number 14 facial cleft: A 20 years follow-up  

Microsoft Academic Search

Here we report a case of a Tessier number 14 cleft, the rarest form of craniofacial cleft, and our step-wise approach to its surgical correction. The patient’s appearance was analyzed over a 20-year follow-up period. At the fourth and final operation, the interorbital distance was reduced, the maxilla was advanced, rib and costal cartilage were grafted for augmentation of the

Seung Min Nam; Yong Bae Kim; Ho Seong Shin

78

Stability of alexithymia in late adolescence: Results of a 4-year follow-up study.  

PubMed

The aim of the present study was to assess the stability of alexithymia in adolescents and the effects of parental factors and social support thereon. The sample comprised 315 late adolescents, of whom 259 were female and 56 male. At baseline, the mean age of the subjects was 19 years (range 17-21 years). The follow-up period was 4 years (2008-2012). The 20-item Toronto Alexithymia Scale (TAS-20) was used for the assessment of alexithymia both at baseline and follow-up. The Multidimensional Scale of Perceived Social Support (MSPSS) and the Parental Bonding Instrument (PBI) were used as measures at baseline. Regarding absolute stability, the changes in the TAS-20 total scores and two subscales (DIF and EOT) were statistically significant but the effect sizes for the changes were small (Cohen?s d 0.21-0.24). The test-retest correlations for the TAS-20 total and subscale scores were high (?=0.50-0.64, P<0.001), indicating relative stability. While several parental and social support variables were associated with alexithymia at baseline, low social support from friends was the only to predict higher alexithymia at follow-up. Alexithymia is a stable personality trait also in late adolescence. Low social support from friends is related to alexithymia in young adulthood. PMID:24953425

Karukivi, Max; Pölönen, Tuukka; Vahlberg, Tero; Saikkonen, Suvi; Saarijärvi, Simo

2014-10-30

79

Ceramic-on-Ceramic Total Hip Arthroplasty: Minimum of Six-Year Follow-up Study  

PubMed Central

Background This study examines the clinical and radiologic results of ceramic-on-ceramic total hip arthroplasties with regard to wear, osteolysis, and fracture of the ceramic after a minimum follow-up of six years. Methods We evaluated the results of a consecutive series of 148 primary ceramic-on-ceramic total hip arthroplasties that had been performed between May 2001 and October 2005 in 142 patients. The mean age was 57.2 years (range, 23 to 81 years). The mean follow-up period was 7.8 years (range, 6.1 to 10.1 years). Preoperative diagnosis was avascular necrosis in 77 hips (52%), degenerative arthritis in 36 hips (24.3%), femur neck fracture in 18 hips (12.2%), rheumatoid arthritis in 15 hips (10.1%), and septic hip sequelae in 2 hips (1.4%). Clinical results were evaluated with the Harris hip score, and the presence of postoperative groin or thigh pain. Radiologic analysis was done with special attention in terms of wear, periprosthetic osteolysis, and ceramic failures. Results The mean Harris hip score improved from 58.3 (range, 10 to 73) to 92.5 (range, 79 to 100) on the latest follow-up evaluation. At final follow-up, groin pain was found in 4 hips (2.7%), and thigh pain was found in 6 hips (4.1%). Radiologically, all femoral stems demonstrated stable fixations without loosening. Radiolucent lines were observed around the stem in 25 hips (16.9%), and around the cup in 4 hips (2.7%). Endosteal new bone formation was observed around the stem in 95 hips (64.2%) and around the cup in 88 hips (59.5%). No osteolysis was observed around the stem and cup. There were 2 hips (1.4%) of inclination changes of acetabular cup, 2 hips (1.4%) of hip dislocation, 1 hip (0.7%) of ceramic head fracture, and 1 hip (0.7%) of squeaking. The Kaplan-Meier survival rate of the prostheses was 98.1% at postoperative 7.8 years. Conclusions The ceramic-on-ceramic total hip arthroplasty produced excellent clinical results and implant survival rates with no detectable osteolysis on a minimum six-year follow-up study. The ceramic-on-ceramic couplings could be a reasonable option of primary total hip arthroplasty for variable indications.

Choy, Won-Sik; Lee, Sang Ki; Bae, Kyoung Wan; Hwang, Yoon Sub; Park, Chang Kyu

2013-01-01

80

Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up  

PubMed Central

From June 2002 to March 2013 26 patients that underwent Stretta procedure (16 females, 10 males) reached to date an eight-year follow-up. Primary end point of the study was to verify the durability of the procedure at this time. All patients underwent clinical evaluation by upper endoscopy, oesophageal pressure, and pH studies. For each patient 8-year data were compared to those recorded at baseline and at 4 years. There was a significant decrease in both heartburn and GERD HRQL scores at 4 years (P = 0.001) and at 8 years (P = 0.003) as well as a significant increase of QoL scores at each control time (mental SF-36 and physical SF-36, P = 0.001). After 4 and 8 years, 21 patients (80.7%, P = 0.0001) and 20 patients (76.9%, P = 0.0001) were completely off PPIs. Median LES pressure did not show significant amelioration at 4 and 8 years and mean oesophageal acid exposure significantly improved at 4 years (P = 0.001) but returned to baseline values after 8 years. This further follow-up study of ours from four to eight years confirms that RF energy delivery for GERD provides durable improvement in symptoms and in quality of life and reduces antireflux drugs consumption.

Dughera, Luca; Rotondano, Gianluca; De Cento, Maria; Cassolino, Paola; Cisaro, Fabio

2014-01-01

81

Controlled two year follow up of rehabilitation for disorders in the neck and shoulders.  

PubMed Central

OBJECTIVE--To evaluate the effects of an early, active, and multidisciplinary rehabilitation programme for neck and shoulder disorders. METHODS--Primary health care and industrial health care of a nonrandomised, controlled, cohort was followed up over two years in a geographically defined area. The cohort consisted of working people who consulted a physician about disorders of the neck or shoulders from 1 August 1988 to 31 October 1989. Criteria for acceptance; not chronic symptoms, patients had sick leave of no more than four weeks. Disorders were not caused by trauma, infections, malignancy, rheumatic diseases, abuse, or pregnancy. 107 people qualified for the study, 87% were followed up for two years. They were divided into two groups. One group obtained active, multidisciplinary rehabilitation for eight weeks that comprised physical training, information, education, social interaction, and work place visits. Controls were given traditional treatment; physiotherapy, medication, rest, and sick leave. The main outcome measures were: average number of days of sick leave for the two years after rehabilitation, subjective pain on a visual analogue scale, and ratings on seven subscales of the sickness impact profile. RESULTS--At 12 and 24 months of follow up effects of the active rehabilitation programme did not differ from traditional treatment in any of the outcome measures. New work task (P < 0.05) or changed work place (P < 0.001) during the follow up period were associated with decreased sick leave, independent of treatment. CONCLUSIONS--Active, multidisciplinary rehabilitation of neck and shoulder disorders was not more effective than traditional treatment. Changed work conditions were associated with decreased sick leave, independent of type of treatment provided.

Ekberg, K; Bjorkqvist, B; Malm, P; Bjerre-Kiely, B; Axelson, O

1994-01-01

82

Infantile-onset diabetes mellitus: a 1-year follow-up study.  

PubMed

This study evaluates the clinical profiles and outcomes of children with infantile-onset diabetes mellitus (IODM) (onset at <1 year). Twelve infants with IODM presenting to our hospital from January 2003 to December 2007 are analyzed. All undergo thorough history, clinical examination, and investigations and are managed as per hospital-approved protocol and periodically followed up. Of 12 infants (3 boys and 9 girls), 9 have a family history of DM. The median age at onset is 2.5 months. Six infants have features suggestive of Wolcott-Rallison syndrome (WRS), 4 infants have type 1 DM, and 1 infant each has Fanconi-Bickel syndrome and maturity-onset diabetes of young. None have pancreatic agenesis or calculi. Human leukocyte antigen (HLA) typing shows DQ3 and DR15 alleles predominating. Two children with WRS died; the rest are being followed up. The incidence of IODM is increasing, with multiple syndromic associations rather than a single perspective. PMID:18836058

Ganesh, Ramaswamy; Arvindkumar, Ravindrakumar; Vasanthi, Thiruvengadam

2009-04-01

83

Three-Year Follow-Up of Syndromal Antisocial Behavior in Adults  

PubMed Central

Objective To present nationally representative findings on total antisocial personality disorder (ASPD) symptoms, major violations of others’ rights (MVOR), and violent symptoms over a 3-year follow-up in Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions among adults diagnosed at Wave 1 with ASPD versus syndromal adult antisocial behavior without conduct disorder before age 15 (AABS, not a codable DSM-IV disorder). Method Face-to-face interviews were conducted with 34,653 respondents 18 years and older. Antisocial syndromes and comorbid lifetime substance use, mood, and 6 additional personality disorders were diagnosed at Wave 1 using the Alcohol Use Disorder and Associated Disabilities Interview Schedule - DSM-IV Version. The Wave 2 Alcohol Use Disorder and Associated Disabilities Interview Schedule - DSM-IV Version assessed antisocial symptoms over follow-up, lifetime attention-deficit/hyperactivity (ADHD) and posttraumatic stress disorders, and borderline, narcissistic, and schizotypal personality disorders. Results In unadjusted analyses, respondents with ASPD reported significantly more total, MVOR, and violent symptoms over follow-up than respondents with AABS. Adjustment for baseline sociodemographics and psychiatric comorbidity attenuated these associations; after further adjustment for parallel antisocial symptom counts from age 15 to Wave 1, associations with antisocial syndromes disappeared. Independent Wave 1 predictors of persistent antisociality over follow-up included male sex, not being married or cohabiting, low income, high school or less education, and lifetime drug use disorders, additional personality disorders, and ADHD. Conclusions The distinction between ASPD and AABS holds limited value in predicting short-term course of antisocial symptomatology among adults. However, the prediction of persistent antisociality by psychiatric comorbidity argues for comprehensive diagnostic assessments, treatment of all identified disorders, and investigation of whether treatment of comorbidity might hasten remission of antisociality.

Goldstein, Rise B.; Grant, Bridget F.

2008-01-01

84

Non-syndrome patient with bilateral supernumerary teeth: Case report and 9-year follow-up  

PubMed Central

The presence of supernumerary teeth, also known as hyperdontia, is the condition of having teeth in addition to the regular number of teeth. The occurrence of multiple supernumerary teeth is often found in association with syndromes such as Gardner syndrome, Anderson-Fabry disease, Ellis-van Creveld syndrome, Ehlers-Danlos syndrome, incontinentia pigmenti, and Tricho-rhino-phalangeal syndrome. Only a few examples of nonsyndromic multiple supernumerary teeth have been reported in literature. In this report, we present the unusual case and 9-year follow up of a non-syndrome female patient with bilateral supernumerary teeth that occurred with an interval of several years.

Akgun, Ozlem Marti; Sabuncuoglu, Fidan; Altug, Ayberk; Altun, Ceyhan

2013-01-01

85

Non-syndrome patient with bilateral supernumerary teeth: Case report and 9-year follow-up.  

PubMed

The presence of supernumerary teeth, also known as hyperdontia, is the condition of having teeth in addition to the regular number of teeth. The occurrence of multiple supernumerary teeth is often found in association with syndromes such as Gardner syndrome, Anderson-Fabry disease, Ellis-van Creveld syndrome, Ehlers-Danlos syndrome, incontinentia pigmenti, and Tricho-rhino-phalangeal syndrome. Only a few examples of nonsyndromic multiple supernumerary teeth have been reported in literature. In this report, we present the unusual case and 9-year follow up of a non-syndrome female patient with bilateral supernumerary teeth that occurred with an interval of several years. PMID:23408107

Akgun, Ozlem Marti; Sabuncuoglu, Fidan; Altug, Ayberk; Altun, Ceyhan

2013-01-01

86

Back posture education in elementary schoolchildren: a 2-year follow-up study  

PubMed Central

Within the scope of primary prevention regarding back functioning in children, research on the stability of intervention effects is indispensable. Along this line, the transition from childhood to adolescence is an important phase to evaluate the potential stability of intervention effects because of the typically mechanical and psychological demands related to adolescence. The main aim of the current study was to investigate the effects of a back education program at 2-year follow-up, in youngsters aged 13–14 years, on back posture knowledge, fear-avoidance beliefs and self-reported pain. An additional purpose was to evaluate which aspects of postural behavior were integrated in youngsters’ lifestyles. At 2-year follow-up, the study sample included 94 secondary schoolchildren in the intervention group (mean age 13.3 ± 0.8 years) and 101 controls (mean age 13.2 ± 0.7 years). The back posture program that had been implemented for two school years consisted of back education and the stimulation of postural dynamism in the class through support and environmental changes. A questionnaire was completed comparable to the pretest, posttest and follow-up evaluations. The current study demonstrated at 2-year follow-up stability of the improved general (F = 1.590, ns) and specific (F = 0.049, ns) back posture knowledge in children who had received early back posture education. Back posture education did not result in increased fear-avoidance beliefs (F = 1.163, ns) or mounting back and/or neck pain reports (F = 0.001, ns). Based on self-reports for postural behavior, youngsters who had received the back posture program in the elementary school curriculum integrated crucial sitting and lifting principles conform to biomechanical favorable postural behavior. The steady intervention effects 2-year post-intervention demonstrated that intensive back posture education through the elementary school curriculum is effective till adolescence. Future research on the impact of early school-based back posture promotion in relation to the integration of back posture principles according to a biomechanical favorable lifestyle and back pain prevalence later in life is essential.

Geldhof, Elisabeth; De Bourdeaudhuij, Ilse; De Clercq, Dirk

2006-01-01

87

Pigmented epithelioid melanocytoma: favorable outcome after 5-year follow-up.  

PubMed

Pigmented epithelioid melanocytoma (PEM) is a recently described entity encompassing epithelioid blue nevus (of Carney complex) and most tumors earlier considered as so-called "animal-type melanoma". Loss of expression of a Carney complex gene, cyclic adenosine 3',5' monophosphate-dependent protein kinase regulatory subunit 1alpha, is observed in the majority of PEMs. Initial reports with short-term follow-up have suggested that although PEMs frequently metastasize to lymph nodes, they have a more favorable outcome than conventional melanomas. In this report, we present the results of long-term follow-up in 26 patients with PEMs from North America and Australia. There were 9 males and 17 females, with a median age of 20 years. The tumors involved the trunk (6 cases), extremities (12 cases), genitalia (1 case), and the head and neck region (7 cases) had a median Breslow thickness of 2.2 mm (range 0.80 to 10.0 mm) and a median Clark level of 4. Eight of the patients developed lymph node metastases. After a median follow-up period of 67 months (range 39 to 216 mo), all patients are alive and free of disease. These findings provide further evidence that PEM is a unique low-grade melanocytic tumor with limited metastatic potential (to lymph nodes), but a favorable long-term clinical course. PMID:19773637

Mandal, Rajni V; Murali, Rajmohan; Lundquist, Kurt F; Ragsdale, Bruce D; Heenan, Peter; McCarthy, Stanley W; Mihm, Martin C; Scolyer, Richard A; Zembowicz, Artur

2009-12-01

88

Simultaneous bilateral total hip arthroplasty with hydroxyapatite-coated implants: a 20-year follow-up.  

PubMed

Bilateral hip arthroplasty has been reported to be a safe and effective way to treat bilateral hip arthritis in a selective group of patients. We report a follow-up of 30 patients who underwent simultaneous bilateral total hip arthroplasty with hydroxyapatite implants and were followed for an average of 19.4 years. Patients had an average Harris Hip Score of 90 at the latest follow-up (range, 78-99). The average Western Ontario and McMaster Universities Arthritis Index questionnaire index score was 12 (range, 0-41), with high functional results on the 12-Item Short Form Health Survey (SF-12) and Oxford 12 questioners. Using the Kaplan-Meier survivorship analysis, with revision for any reason as an end point, survivorship was 94% at 12 years, 88% at 15 years, 74% at 18 years, and 61% at 23 years. All revisions were for the acetabular component, and the survivorship for the femoral component was 100% throughout the 23-year period. We conclude that bilateral uncemented total hip arthroplasty can provide satisfactory long-term clinical, radiological, and functional outcomes in patients even with older-generation polyethylene liners and stem designs. PMID:22177794

Schwarzkopf, Ran; Olivieri, Patrick; Jaffe, William L

2012-08-01

89

Schizophrenia and quality of life: a one-year follow-up in four EU countries  

PubMed Central

Background This article systematically monitors the quality of life (QOL) of patients with schizophrenia from seven different sites across four European countries: France, Ireland, Portugal and Spain. Methods A one-year prospective cohort study was carried out. Inclusion criteria for patients were: a clinical lifetime diagnosis of schizophrenia according to ICD-10 (F20) diagnostic criteria for research, age between 18 and 65 years and at least one contact with mental health services in 1993. Data concerning QOL were recorded in seven sites from four countries: France, Portugal, Ireland and Spain, and were obtained using the Baker and Intagliata scale. At baseline, 339 patients answered the QOL questionnaire. At one-year follow-up, Spain could not participate, so only 263 patients were contacted and 219 agreed to take part. QOL was compared across centres by areas and according to a global index. QOL was correlated with presence of clinical and social problems, needs for care and interventions provided during the one-year follow-up. Results We did not find any link between gender and QOL. There were some significant differences between centres concerning many items. What is more, these differences were relative: in Lisbon where the lowest level of satisfaction was recorded, people were satisfied with food but highly dissatisfied with finances, whereas in St Etienne, where the highest level of satisfaction was recorded, people were less satisfied with food when they were more satisfied with finances. The evolution in one year among those respondents who took part in the follow-up (excluding the subjects from Granada) showed different patterns depending on the items. Conclusion The four countries have different resources and patients live in rather different conditions. However, the main differences as far as their QOL is concerned very much depend on extra-psychiatric variables, principally marital status and income.

Kovess-Masfety, Viviane; Xavier, Miguel; Moreno Kustner, Berta; Suchocka, Agnieszka; Sevilla-Dedieu, Christine; Dubuis, Jacques; Lacalmontie, Elisabeth; Pellet, Jacques; Roelandt, Jean-Luc; Walsh, Dermot

2006-01-01

90

Cognitive evolution in hypertensive patients: a six-year follow-up  

PubMed Central

Background: Several studies have examined the links between hypertension, vascular damage, and cognitive impairment. The functions most commonly involved seem to be those associated with memory and executive function. Aims: 1) to report the cognitive evolution in a cohort of hypertensive patients, 2) to identify the affected domains, and 3) to correlate the results obtained with blood pressure measurements. Materials and Methods: Observational 6-year follow-up cohort study including both males and females aged ?65 and ?80 years, and hypertensive patients under treatment. Patients with a history of any of the following conditions were excluded: stroke, transient ischemic attack, diabetes mellitus, atrial fibrillation, cardiac surgery, dementia, or depression. Four neurocognitive evaluations were performed (at baseline and every 2 years). The tests used evaluated memory and executive function domain. Blood pressure was measured on every cognitive evaluation. Results: Sixty patients were followed for 76.4 ± 2.8 months. The average age at baseline was 72.5 ± 4.2 and 77.9 ± 4.6 at 6 years (65% were women). Two patients were lost to follow up (3.3%) and 8 patients died (13.3%).The density incidence for dementia was 0.6% patients per year (pt/y) (n = 3) and for depression was 1.6% pt/y (n = 12). No changes were observed in either memory impairment or the Mini Mental State Examination (MMSE) results (p = ns) during follow-up. A progressive impairment of the executive function was shown regardless of the blood pressure measurements. Conclusion: 1) the incidence of dementia doubled to general population, 2) the initial memory impairment did not change during the evaluation period, 3) cognitive impairment worsened in the areas related to executive function (prefrontal cortex) regardless of the adequacy of anti-hypertensive treatment and blood pressure values.

Vicario, Augusto; del Sueldo, Mildren A; Zilberman, Judith M; Cerezo, Gustavo H

2011-01-01

91

Family support and depressive symptoms: a 23-year follow-up.  

PubMed

We examined change in family support and depressive symptoms over the course of 23 years and included the potential moderators of gender and participation in treatment. A sample of 373 depressed individuals provided data in five waves, with baseline, 1-year, 4-year, 10-year, and 23-year follow-ups. Multilevel modeling was used to evaluate longitudinal relationships between variables. Higher family support was associated with less depression at baseline and predicted a steeper trajectory of recovery from depression over 23 years. This relationship was moderated by gender, such that women with supportive families reported the most rapid recovery from depression. Evaluating family context may be clinically relevant when beginning treatment with a depressed patient, particularly for female patients. PMID:21254050

Kamen, Charles; Cosgrove, Victoria; McKellar, John; Cronkite, Ruth; Moos, Rudolf

2011-03-01

92

Ten-Year Follow-Up of Endovascular Aneurysm Treatment with Talent Stent-Grafts  

SciTech Connect

The purpose of this study was to evaluate the clinical results, complications, and secondary interventions during long-term follow-up after endovascular aneurysm repair (EVAR) and to investigate the impact of endoleak sizes on aneurysm shrinkage. From 1997 to March 2007, 127 patients (12 female, 115 male; age, 73.0 {+-} 7.2 years) with abdominal aortic aneurysms were treated with Talent stent-grafts. Follow-up included clinical visits, contrast-enhanced MDCT, and radiographs at 3, 6, and 12 months and then annually. Results were analyzed with respect to clinical outcome, secondary interventions, endoleak rate and management, and change in aneurysm size. There was no need for primary conversion surgery. Thirty-day mortality was 1.6% (two myocardial infarctions). Procedure-related morbidity was 2.4% (paraplegia, partial infarction of one kidney, and inguinal bleeding requiring surgery). Mean follow-up was 47.7 {+-} 34.2 months (range, 0-123 months). Thirty-nine patients died during follow-up; three of the deaths were related to aneurysm (aneurysm rupture due to endoleak, n = 1; secondary surgical reintervention n = 2). During follow-up, a total of 29 secondary procedures were performed in 19 patients, including 14 percutaneous procedures (10 patients) and 15 surgical procedures (12 patients), including 4 cases with late conversion to open aortic repair (stent-graft infection, n = 1; migration, endoleak, or endotension, n = 3). Overall mean survival was 84.5 {+-} 4.7 months. Mean survival and freedom from any event was 66.7 {+-} 4.5 months. MRI depicted significantly more endoleaks compared to MDCT (23.5% vs. 14.3%; P < 0.01). Patients in whom all aneurysm side branches were occluded prior to stent-grafting showed a significantly reduced incidence of large endoleaks. Endoleaks >10% of the aneurysm area were associated with reduced aneurysm shrinkage compared to no endoleaks or <10% endoleaks ({Delta} at 3 years, -1.8% vs. -12.0%; P < 0.05). In conclusion, endovascular aneurysm treatment with Talent stent-grafts demonstrated encouraging long-term results with moderate secondary intervention rates. Primary occlusion of all aortic side branches reduced the incidence of large endoleaks. Large endoleaks significantly impaired aneurysm shrinkage, whereas small endoleaks did not.

Pitton, Michael B., E-mail: pitton@radiologie.klinik.uni-mainz.de; Scheschkowski, Tobias; Ring, Markus; Herber, Sascha; Oberholzer, Katja; Leicher-Dueber, Annegret [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Diagnostic and Interventional Radiology (Germany); Neufang, Achim; Schmiedt, Walther [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Cardiovascular and Thoracic Surgery (Germany); Dueber, Christoph [University Hospital of Mainz, Johannes Gutenberg University of Mainz, Department of Diagnostic and Interventional Radiology (Germany)

2009-09-15

93

Pancreas-kidney transplantation: complications and readmissions in 9-years of follow-up.  

PubMed

Over 9 years, we have performed 93 simultaneous pancreas-kidney transplants (SPKT). The morbidity of this procedure is high compared with kidney transplantation alone; readmissions are frequent and costs are higher. Herein we have presented the complications during follow-up of these 93 patients. Their mean age was 34 +/- 6 years and prior dialysis time was 32 +/- 25 months. The median hospital stay on the first admission for the transplant procedure was 22 days, including 2 days in the intensive care unit. Bleeding, thrombosis, and infection were the most frequent reasons for prolonged hospitalization. Thirty patients underwent >or=1 surgical reinterventions. Incidence of acute rejection episodes was 11.8%. After discharge, 74.2% of the patients had 197 readmission episodes with infection being the main cause, urinary tract infections, the most frequent; however, systemic viral and fungal infections required the longest readmission periods. The need for surgical interventions, graft dysfunction, and vascular problems were the remaining causes of readmission. At the end of follow-up, 87 patients were alive, 86 with well-functioning kidneys and 74 with normal functioning pancreata. Global survival rates for patient, kidney, and pancreas were 96%, 95%, and 81% at 1-year; 93%, 90%, and 79% at 5-years; and 93%, 90% and 79% at 9-years. Although pancreas-kidney transplant patients are complex presenting many management difficulties, our overall results represent a positive stimulus for diabetic patients. PMID:20304190

Martins, L; Henriques, A C; Dias, L; Almeida, M; Pedroso, S; Freitas, C; Pereira, S; Fructuoso, M; Dores, J; Oliveira, F; Almeida, R; Cabrita, A; Teixeira, M

2010-03-01

94

Clinical and radiological results of the collarless polished tapered stem at 15 years follow-up.  

PubMed

We prospectively followed 191 consecutive collarless polished tapered (CPT) femoral stems, implanted in 175 patients who had a mean age at operation of 64.5 years (21 to 85). At a mean follow-up of 15.9 years (14 to 17.5), 86 patients (95 hips) were still alive. The fate of all original stems is known. The 16-year survivorship with re-operation for any reason was 80.7% (95% confidence interval 72 to 89.4). There was no loss to follow-up, with clinical data available on all 95 hips and radiological assessment performed on 90 hips (95%). At latest follow-up, the mean Harris hip score was 78 (28 to 100) and the mean Oxford hip score was 36 (15 to 48). Stems subsided within the cement mantle, with a mean subsidence of 2.1 mm (0.4 to 19.2). Among the original cohort, only one stem (0.5%) has been revised due to aseptic loosening. In total seven stems were revised for any cause, of which four revisions were required for infection following revision of the acetabular component. A total of 21 patients (11%) required some sort of revision procedure; all except three of these resulted from failure of the acetabular component. Cemented acetabular components had a significantly lower revision burden (three hips, 2.7%) than Harris Galante uncemented components (17 hips, 21.8%) (p < 0.001). The CPT stem continues to provide excellent radiological and clinical outcomes at 15 years following implantation. Its results are consistent with other polished tapered stem designs. PMID:22733941

Burston, B J; Barnett, A J; Amirfeyz, R; Yates, P J; Bannister, G C

2012-07-01

95

Controlled trial of antituberculous chemotherapy in Crohn's disease: a five year follow up study  

PubMed Central

Background—It has been suggested that Mycobacterium paratuberculosis is the cause of Crohn's disease. In a previous report the immediate effect of two years treatment with antituberculous chemotherapy showed no clinical benefit. ?Aims—To assess both the immediate and longer term effect of treatment on the disease. ?Methods—Patients were followed for five years from their date of entry to the study. One hundred and thirty patients entered the initial study, and of these 111 (81%) were followed regularly. ?Results—Overall, there was no evidence of consistent benefit or disadvantage from antituberculous chemotherapy in any of the assessments made, including the number of acute relapses, surgical episodes, hospital admissions, disease activity, blood tests, or medication required for Crohn's disease during the follow up period. ?Conclusion—The absence of any benefit at the end of the initial two year trial period, and during the three year subsequent follow up, fails to support the hypothesis that mycobacteria play an important part in the pathogenesis of Crohn's disease, or that antituberculous chemotherapy may be of benefit. ?? Keywords: Crohn's disease; mycobacteria; antituberculus chemotherapy

Thomas, G; Swift, G; Green, J; Newcombe, R; Braniff-Mathews, C; Rhodes, J; Wilkinson, S; Strohmeyer, G; Kreuzpainter, G

1998-01-01

96

Comparative Evaluation of Gingival Depigmentation using Tetrafluoroethane Cryosurgery and Gingival Abrasion Technique: Two Years Follow Up.  

PubMed

Objective: A comparative evaluation of the gingival depigmentation by using Tetrafluoroethane cryosurgery and the gingival abrasion technique - 2 years of follow up. Material and Methods: Ten systemically healthy patients who were aged 18 to 36 years were selected for the study. Tetrafluoroethane was used for the cryosurgical depigmentation and the gingival abrasion technique used a coarse flame shaped bur. The presence or absence of pigmentation was tabulated, based on the GPI (Gingival Pigmentation Index). For the statistical analysis, Freidman's test was used. Results: The keratinization was completed within a week after the application of the cryogen and about 10 days after the gingival abrasion technique was done. The statistical analysis which was done after 90th, 180th days and 2 years. The p-value which was obtained (p<.001) showed the superiority of cryosurgery over the gingival abrasion. During the follow up period, no side effects were seen for both the techniques and the improved aesthetics was maintained upto 2 years. Conclusion: The use of cryogen Tetrafluoroethane is easy, practical and inexpensive as compared to gingival abrasion, due to its high rate of recurrence. Hence, it is more acceptable to the patients and the operator. Further studies are needed to assess the long term effectiveness of the cryosurgical method of depigmentation. PMID:23543863

Kumar, Santhosh; Bhat, G Subraya; Bhat, K Mahalinga

2013-02-01

97

Screen detected high blood pressure under 40: a general practice population followed up for 21 years.  

PubMed Central

OBJECTIVE--To assess hypertension detected under 40 in a general practice population. DESIGN--Prospective case-control study. SETTING AND SUBJECTS--Former coal mining community in south Wales. Systematic case finding for hypertension and associated risk factors applied to a mean total population of 1945 from age 20 on a five year cycle through 21 years. Mean population aged 20-39, 227 men and 213 women. Case criteria: age < 40 and mean systolic pressure > or = 160 mm Hg or diastolic pressure > or = 100 mm Hg. Age and sex matched controls randomly sampled from the same population. MAIN OUTCOME MEASURES--Mean initial pressures and pressures at follow up in 1989 or preceding death, and all cardiovascular events. RESULTS--25 men and 16 women met criteria. Estimated five yearly inceptions were 26/1000 for men and 18/1000 for women. Male group mean initial blood pressure was 164/110 mm Hg for cases, falling to 148/89 mm Hg at follow up. Five male cases died at mean age 47.8, compared with two controls at 49.5. Female group mean initial pressure was 172/107 mm Hg for cases, falling to 145/86 mm Hg at follow up. One female case died aged 50, no controls. 10 male cases had non-fatal cardiovascular events at mean age 40.2, compared with two controls at mean age 50.5. Four female cases had non-fatal events at mean age 47.2, compared with one control aged 58. Male differences were statistically significant. CONCLUSIONS--Hypertension under 40 is dangerous, commoner in men than women, rarely secondary to classic causes, and may be controlled in general practice on a whole community basis.

Hart, J T; Edwards, C; Hart, M; Jones, J; Jones, M; Haines, A; Watt, G

1993-01-01

98

A Prospective, 1-Year Follow-up Study of Postural Tachycardia Syndrome  

PubMed Central

Objective To prospectively evaluate patients who met standard criteria for postural tachycardia syndrome (POTS), at baseline and 1-year follow-up, using standard clinical and laboratory methods to assess autonomic function. Methods Fifty-eight patients met the study criteria (orthostatic symptoms and a heart rate increment of ?30 beats/min on head-up tilt) and completed 12 months of follow-up. All patients were enrolled and completed the study from January 16, 2006, through April 15, 2009. Patients underwent standardized autonomic testing, including head-up tilt, clinical assessment, and validated questionnaires designed to determine the severity of autonomic symptoms. Results Patients were predominantly young females (n=49, 84%), with 20 patients (34%) reporting an antecedent viral infection before onset of symptoms. More than one-third (37%) no longer fulfilled tilt criteria for POTS on follow-up, although heart rate increment on head-up tilt did not differ significantly at 1 year (33.8±15.1 beats/min) compared with baseline (37.8±14.6 beats/min) for the entire cohort. Orthostatic symptoms improved in most patients. Autonomic dysfunction was mild as defined by a Composite Autonomic Severity Score of 3 or less in 55 patients (95%) at baseline and 48 patients (92%) at 1 year. Conclusion To our knowledge, this is the first prospective study of the clinical outcomes of patients with POTS. Orthostatic symptoms improved in our patients, with more than one-third of patients no longer fulfilling tilt criteria for POTS, although the overall group change in heart rate increment was modest. Our data are in keeping with a relatively favorable prognosis in most patients with POTS.

Kimpinski, Kurt; Figueroa, Juan J.; Singer, Wolfgang; Sletten, David M.; Iodice, Valeria; Sandroni, Paola; Fischer, Philip R.; Opfer-Gehrking, Tonette L.; Gehrking, Jade A.; Low, Phillip A.

2012-01-01

99

Australian Aboriginal Birth Cohort study: follow-up processes at 20 years  

PubMed Central

Background In 1987, a prospective study of an Australian Aboriginal Birth Cohort was established focusing on the relationships of fetal and childhood growth with the risk of chronic adult disease. However as the study is being conducted in a highly marginalized population it is also an important resource for cross-sectional descriptive and analytical studies. The aim of this paper is to describe the processes of the third follow up which was conducted 20 years after recruitment at birth. Methods Progressive steps in a multiphase protocol were used for tracing, with modifications for the expected rural or urban location of the participants. Results Of the original 686 cohort participants recruited 68 were untraced and 27 were known to have died. Of the 591 available for examination 122 were not examined; 11 of these were refusals and the remainder were not seen for logistical reasons relating to inclement weather, mobility of participants and single participants living in very remote locations. Conclusion The high retention rate of this follow-up 20 years after birth recruitment is a testament to the development of successful multiphase protocols aimed at overcoming the challenges of tracing a cohort over a widespread remote area and also to the perseverance of the study personnel. We also interpret the high retention rate as a reflection of the good will of the wider Aboriginal community towards this study and that researchers interactions with the community were positive. The continued follow-up of this life course study now seems feasible and there are plans to trace and reexamine the cohort at age 25 years.

2009-01-01

100

Ultrasonographically detected gallbladder polyps: A reason for concern? A seven-year follow-up study  

PubMed Central

Background The management of coincidental detected gallbladder polyps (GP) is still nebulous. There are few published data regarding their long-term growth. Objective of the present study was to investigate the prevalence and growth of gallbladder polyps in a survey of unselected subjects from the general population of a complete rural community. Methods A total of 2,415 subjects (1,261 women; 1,154 men) underwent ultrasound examination of the gallbladder, in November 1996 as part of a prospective study. Subjects in whom GP were detected at the initial survey underwent follow-up ultrasound examinations after 30 and 84 months. Results At the initial survey gallbladder polyps were detected in 34 subjects (1.4%; females: 1.1%, range 14 to 74 years; males: 1.7%, range 19 to 63 years). Median diameter was 5 ± 2.1 mm (range 2 to10 mm) at the initial survey, 5 mm ± 2.8 mm (range 2 to 12 mm) at 30 months and 4 ± 2.3 mm (range 2 to 9 mm) at 84 months. At the time of first follow-up no change in diameter was found in 81.0% (n = 17), reduction in diameter in 4.8% (n = 1) and increase in diameter in 14.3% (n = 3). At the time of second follow-up no increase in polyp diameter was found in 76.9% (n = 10) and reduction in diameter in 7.7% (n = 1). No evidence of malignant disease of the gallbladder was found. Conclusion Over a period of seven years little change was measured in the diameter of gallbladder polyps. There was no evidence of malignant disease of the gallbladder in any subject.

Kratzer, Wolfgang; Haenle, Mark M; Voegtle, Andrea; Mason, Richard A; Akinli, Atilla S; Hirschbuehl, Klaus; Schuler, Andreas; Kaechele, Volker

2008-01-01

101

Undifferentiated spondyloarthritis in a heterogeneous Brazilian population: an eight-year follow-up study.  

PubMed

The aim of the present study was to describe the outcomes of Brazilian patients with undifferentiated spondyloarthritis during an eight-year follow-up period. Patients fulfilling the European Spondyloarthritis (SpA) Study Group Classification Criteria were enrolled. Forty patients were seen at baseline, and 36 participated in the follow-up study. Twenty-three (58 %) were female, and there were 24 (60 %) African Brazilians enrolled. HLA-B27 was positive in 18 (45 %) patients. At disease onset, the first presenting symptoms were pure peripheral manifestations in 26 (72.2 %) patients. After the study period, mixed disease (axial + peripheral) predominated occurring in 25 (69.4 %) patients. The Assessment of SpA International society (ASAS) classification criteria for axial SpA were fulfilled by 77 % of patients, and the ASAS criteria for peripheral SpA were fulfilled by 59 % of patients. After 2.5 years, 6 (16.7 %) of the 36 patients fulfilled the modified New York Criteria for ankylosing spondylitis and 1 (2.7 %) progressed to psoriatic arthritis. A total of 10 (27.8 %) patients progressed to definite SpA during the eight-year study period. Buttock pain (p = 0.006, OR 10.55; 95 % CI 2.00-65.90) and low-grade radiographic sacroiliitis (p = 0.025, OR = 11.50; 95 % CI 1.33-83.39) at baseline were associated with definite SpA. Thus, in this Brazilian cohort, which had a predominance of female African-Brazilian patients, prevalent peripheral onset symptoms were followed by a high frequency of axial manifestations during the follow-up period. Evidence of clinical or radiological sacroiliitis was associated with progression to definite SpA. PMID:23765202

da Cruz Lage, Ricardo; de Souza Bomtempo, Carlos Alexandre; Kakehasi, Adriana Maria; de Carvalho, Marco Antônio Parreiras

2014-07-01

102

Predictors of psychosis: a 50-year follow-up of the Lundby population  

Microsoft Academic Search

Behavioural and neuropsychological vulnerability have been associated with an increased risk of psychosis. We investigated\\u000a whether certain clusters of premorbid behavioural and personality-related signs and symptoms were predictors of nonaffective\\u000a and\\/or affective psychosis and schizophrenia, respectively, in a 50-year follow-up of an unselected general community population.\\u000a Total population cohorts from the same catchment area in 1947 (n = 2,503) and 1957 (n = 3,215)

Mats Bogren; Cecilia Mattisson; Kristian Tambs; Vibeke Horstmann; Povl Munk-Jørgensen; Per Nettelbladt

2010-01-01

103

Treatment of lacrimal stenoses obstructions with interventional radiology: immediate and 5-year follow-up results  

Microsoft Academic Search

Purpose  This study was undertaken to evaluate the effectiveness of the Song stent in patients with nasolacrimal duct obstruction.\\u000a \\u000a \\u000a \\u000a Materials and methods  Between 2003 and 2007, we treated 76 consecutive nasolacrimal obstructions in 73 patients (mean age 56 years; range 19–81)\\u000a with implantation of polyurethane stents. Indications were epiphora in 46 patients, dacryocystitis in 18 and recurrent conjunctivitis\\u000a in three. Average follow-up

P. Preziosi; M. Di Primio; T. Erdembileg; R. Mancino; G. D’Este; L. Cerulli; G. Simonetti

2008-01-01

104

Surgical repair of muscle laceration: biomechanical properties at 6 years follow-up.  

PubMed

Muscle injuries are challenging problems for surgeons. Muscle trauma is commonly treated conservatively with excellent outcome results while surgical repair is advocated for larger tears/lacerations, where the optimal goal is restore of function. Repair of muscle belly lacerations is technically demanding because the sutures pull out and the likelihood of clinical failure is high. Different suture techniques have been described but still the best suture is debated. We show a case of a pure vastus medialis muscle laceration surgically repaired at 6 years of follow-up. PMID:24596695

Oliva, Francesco; Via, Alessio Giai; Kiritsi, Olga; Foti, Calogero; Maffulli, Nicola

2013-10-01

105

Changing ocular prostheses in growing children: a 5-year follow-up clinical report.  

PubMed

Eye loss in children can be caused by trauma, glaucoma, or cancer, and may result in anxiety and depression. Recovery after eye loss involves a replacement with a custom-made eye prosthesis, but, as the patient ages, changes in the size and shape of the eye socket can result in a sunken appearance of the child's prosthetic eye. This article describes the fabrication of a custom-made eye and the necessity of changing ocular prostheses for a growing child, with a 5-year follow-up. PMID:24370389

Shaikh, Sameera R; Gangurde, Arti P; Shambharkar, Vaibhao I

2014-04-01

106

The First Year Inventory: A Longitudinal Follow-Up of 12-Month-Old to 3-Year-Old Children  

ERIC Educational Resources Information Center

The First Year Inventory is a parent-report measure designed to identify 12-month-old infants at risk for autism spectrum disorder. First Year Inventory taps behaviors that indicate risk in the developmental domains of sensory--regulatory and social--communication functioning. This longitudinal study is a follow-up of 699 children at 3 years of…

Turner-Brown, Lauren M.; Baranek, Grace T.; Reznick, J Steven; Watson, Linda R.; Crais, Elizabeth R.

2013-01-01

107

Thirty-year follow-up of a TMD case treated based on the neuromuscular concept.  

PubMed

Aim: Occlusal therapy is employed to alleviate the symptoms of a temporomandibular disorder (TMD) at times. However, the long-term effect of occlusal therapy in the masticatory system is not well understood. This case study aims to present a 30-year follow-up of a TMD case. Methodology: The patient developed TMD with intermittent closed lock of the left temporomandibular joint (TMJ). Chief complaints included trismus, pain, and noise of the left TMJ during function. The patient's occlusal disharmony was assessed with use of electronic instruments and corrected based on the neuromuscular concept. A minimum-invasive and reversible approach using adhesive occlusal restorations was used. Results: The jaw movement and masticatory muscle activity assessed at the 7- and 23-year follow-ups revealed that the established occlusion was well adapted, and re-established the patient's functional occlusion system. The patient has been free from TMD symptoms with the corrected occlusion for 30 years. Conclusions: Occlusal reconstruction based on the neuromuscular concept can be stably integrated into the patient's functional occlusion system. PMID:25000166

Yamashita, Atsushi; Kondo, Yasuhiro; Yamashita, Junro

2014-07-01

108

Induction of Maturogenesis by Partial Pulpotomy: 1 Year Follow-Up  

PubMed Central

In cariously exposed immature permanent teeth, the treatment choice is controversial in pediatric dentistry. Radical root canal treatment usually appears to be the solution for these teeth. Even partial pulpotomy is a vital treatment for traumatically exposed immature permanent teeth; extending the borders of indication towards cariously exposed immature permanent teeth with reversible pulpitis may abolish the necessity of pulpectomy. This article describes the partial pulpotomy of a cariously affected immature permanent teeth and the follow-up for 1 year. A healthy 11-year-old male patient was referred to Gazi University Faculty of Dentistry Department of Pediatric Dentistry. The patient had reversible pulpitis symptoms on teeth numbered 45. At radiographic examination, immature apex and deep caries lesion were observed and partial pulpotomy was performed by using calcium hydroxide to maintain vitality of the pulp and allow continued development of root dentin expecting the root will attain full maturity. Clinical and radiographic follow-up demonstrated a vital pulp besides not only closure of the apex (apexogenesis), but also physiologic root development (maturogenesis) after 1 year. Partial pulpotomy is an optional treatment for cariously exposed immature permanent teeth for preserving vitality and physiological root development.

Bacaksiz, A.; Alacam, A.

2013-01-01

109

Ten-year follow-up of an anatomical hydroxyapatite-coated total hip prosthesis  

PubMed Central

We report our results after ten year follow-up of 107 consecutive ABG-I hip prostheses implanted between June 1990 and December 1992: Only 84 prostheses were still in the study after ten years, but only six patients had undergone surgical revision. We can consider our clinical outcomes as excellent, with a whole-implant survival rate greater than 96%, a mean Merle D’Aubigne and Postel score increasing from 7.97 before operation to 16.17 at ten year follow-up, and a personal subjective assessment as excellent or good in 82.14% of patients. However, radiographic outcomes are more worrying: around 90% of patients show a stress-shielding phenomenon and granulomatous lesions in the proximal femur, and more than 82% suffer polyethylene wear greater than one  millimetre (mean 1.68 mm). We think that zirconia stem heads and hooded antiluxation PE inserts are determining factors in the process of PE wear and, secondarily, in cancellous bone resorption and bone osteolysis.

Panisello Sebastia, J. J.; Herrera Rodriguez, A.; Peguero Bona, A.; Martinez Martin, A.; Herrero Barcos, L.; Garcia-Dihinx, L.

2006-01-01

110

Arthroscopic arthrodesis of the shoulder: Fourteen-year follow-up  

PubMed Central

Shoulder arthrodesis is indicated in infections, brachial paralysis, irreparable rotator cuff tears, osteoarthritis without indication of prosthesis, rescue after arthroplasty, or after surgery for cancer. Arthroscopic arthrodesis is exceptional. Our aim is presenting our result after 14 years of follow-up of one patient. We present a case report of a 17-year-old male patient. He suffered fracture of left scapula (type V, Ideberg), fracture of left clavicle (type I, Craig), and fracture of left distal ulna. We realized osteosynthesis of clavicle (plate and screws) with the aim of treating this floating shoulder. Electromyography showed partial axonotmesis of axilar nerve. After 7 months of follow-up, axonotmesis was still present. We realized arthroscopic shoulder arthrodesis (three cannulated screws). Fourteen years later, shoulder movement was as follows: Flexion, 0-90°; maximum abduction, 40° with shoulder atrophy; Constant, 47 points; and UCLA, 17 points, without pain. Arthrodesis with screws reaches a subjective benefit in 82% of patients. Percentage of pseudarthrosis is less than in patients treated with plates, although the risks of infections, fractures, and material removal are greater than in patients treated with plates. Shoulder arthroscopic arthrodesis is exceptional, but it allows minimal surgical aggression.

Jimenez-Martin, Antonio; Perez-Hidalgo, Santiago

2011-01-01

111

Arthroscopic arthrodesis of the shoulder: Fourteen-year follow-up.  

PubMed

Shoulder arthrodesis is indicated in infections, brachial paralysis, irreparable rotator cuff tears, osteoarthritis without indication of prosthesis, rescue after arthroplasty, or after surgery for cancer. Arthroscopic arthrodesis is exceptional. Our aim is presenting our result after 14 years of follow-up of one patient. We present a case report of a 17-year-old male patient. He suffered fracture of left scapula (type V, Ideberg), fracture of left clavicle (type I, Craig), and fracture of left distal ulna. We realized osteosynthesis of clavicle (plate and screws) with the aim of treating this floating shoulder. Electromyography showed partial axonotmesis of axilar nerve. After 7 months of follow-up, axonotmesis was still present. We realized arthroscopic shoulder arthrodesis (three cannulated screws). Fourteen years later, shoulder movement was as follows: Flexion, 0-90°; maximum abduction, 40° with shoulder atrophy; Constant, 47 points; and UCLA, 17 points, without pain. Arthrodesis with screws reaches a subjective benefit in 82% of patients. Percentage of pseudarthrosis is less than in patients treated with plates, although the risks of infections, fractures, and material removal are greater than in patients treated with plates. Shoulder arthroscopic arthrodesis is exceptional, but it allows minimal surgical aggression. PMID:21897586

Jiménez-Martín, Antonio; Pérez-Hidalgo, Santiago

2011-04-01

112

Relapse rates and a 10-year follow-up of a 6-week quadruple drug regimen for multibacillary leprosy.  

PubMed

Between 1989 and 1993, 136 multibacillary leprosy patients received a 6-week treatment regimen consisting of daily rifampicin 600 mg, ofloxacin 400 mg, clofazimine 100 mg and a weekly dose of 100 mg minocycline. A previous analysis after a mean follow-up of 4-7 years revealed a relapse rate of 2%, involving six late (after more than 5 years of follow-up) relapses. During the following years, 12 more relapses appeared during years 8-9 of follow-up. A mean follow-up period of 5 years is insufficient to evaluate treatment regimens in multibacillary leprosy. The present regimen cannot be recommended. PMID:12449889

Pattyn, S; Grillone, S

2002-09-01

113

Radiological progression and lung function in silicosis: a ten year follow up study.  

PubMed Central

Chest radiographs and spirometric tests were performed on 81 patients who had silicosis from two granite quarries in 1975, 73 of whom were followed up for two to 10 (mean 7.2) years. Each patient's initial and most recent chest radiographs were assessed independently by three experienced readers, and the yearly declines in forced expiratory volume in one second and forced vital capacity were estimated from two to four (mean 3.45) serial spirometric readings. Estimates of individual dust exposure were based on extensive historical data on hygiene. All but 11 patients were no longer exposed to dust by the start of follow up, but 24 (45%) of 53 patients who had simple silicosis and 11 (55%) of 20 who had the complicated disease showed radiological evidence of disease progression. In patients who had simple silicosis and showed no radiological progression the yearly declines in forced expiratory volume in one second and forced vital capacity were modest (64 ml/year and 59 ml/year, respectively), whereas significantly greater declines in lung function were seen in those who showed radiological evidence of progression (97 ml/year and 95 ml/year, respectively). In addition to radiological progression the previous average dust concentration to which patients had been exposed also influenced declines in both forced expiratory volume in one second and forced vital capacity after allowing for the effects of age, smoking, duration of exposure, history of tuberculosis, initial state of disease, and baseline lung function. The probability of radiological progression was most strongly influenced by the average dust concentration previously exposed to. The progression of simple silicosis is thus accompanied by appreciable declines in lung function and is strongly affected by previous levels of exposure to dust.

Ng, T P; Chan, S L; Lam, K P

1987-01-01

114

Randomized trial of partial vs. stepwise caries removal: 3-year follow-up.  

PubMed

This randomized, multicenter clinical trial evaluated the effectiveness of 2 treatments for deep caries lesions - partial caries removal (PCR) and stepwise excavation (SW) - with respect to the primary outcome of pulp vitality for a 3-year follow-up period. Inclusion criteria were as follows: patients with permanent molars presenting deep caries lesions (lesion affecting ? 1/2 of the dentin on radiographic examination), positive response to a cold test, absence of spontaneous pain, negative sensitivity to percussion, and absence of periapical lesions (radiographic examination). Teeth randomly assigned to PCR (test) received incomplete caries removal and filling in a single session. Outcome success was evaluated by assessment of pulp vitality, determined by pulp sensitivity to a cold test and the absence of periapical lesions. Data were analyzed by a Weibull regression model with shared frailty term (survival analysis). At baseline, 299 treatments were executed: PCR, 152 and SW, 147. By the end of the 3-year follow-up period, 213 teeth had been evaluated. Adjusted survival rates were 91% for PCR and 69% for SW (p = 0.004). These results suggest that there is no need to re-open a cavity and perform a second excavation for pulp vitality to be preserved (Clinical trials registration NCT00887952). PMID:22983407

Maltz, M; Garcia, R; Jardim, J J; de Paula, L M; Yamaguti, P M; Moura, M S; Garcia, F; Nascimento, C; Oliveira, A; Mestrinho, H D

2012-11-01

115

Pre-clinical Crohn's disease: Diagnosis, treatment and six year follow-up.  

PubMed

Diagnosis of Crohn's disease is usually made at a symptomatic stage. However diagnosis at a pre-clinical stage might provide valuable information on etiology/pathogenesis and allow early intervention to alter its natural history. We describe here the case of a 27year old woman who was diagnosed with Crohn's disease at a completely asymptomatic stage and followed up for more than six years. She was part of an ongoing screening study in first degree relatives of Crohn's disease patients. At diagnosis, colonoscopy showed modest inflammation and few superficial ulcerations and erosions in the ileo-cecal valve and the terminal ileum. Fecal calprotectin was only modestly elevated. Intestinal permeability was also increased. During follow-up and while still asymptomatic the patient was sequentially treated with therapeutic doses of 5-ASA, budesonide, azathioprine and infliximab in an attempt to stop disease progression. Only infliximab appeared capable of inducing profound mucosal healing-however the disease recurred several months after the medication was ceased. Over time, quantification by immunohistochemistry of a number of cell types and cytokines revealed a positive correlation between CD4-CD25-FOXP3 (Treg) cell number and inflammation, a finding potentially consistent with tissue resistance to Tregs' activity. PMID:24411923

Sorrentino, Dario; Avellini, Claudio; Geraci, Marco; Vadalà, Salvatore

2014-07-01

116

High tibial osteotomy for medial osteoarthritis of the knee: 15 years follow-up.  

PubMed

We reviewed 192 patients (224 knees) to assess the results of HTO in medial gonarthrosis during the period 1982-2008. Median follow-up was about 15 years for 134 females and 58 males. Among the knees, 118 had an average opening wedge for varus angle of 13 degrees and 106 had closing wedges of 11 degrees. Knee Society scoring before osteotomies was 68/200 for opening wedge and 81/200 for closing wedge. Modified Ahlback classification showed preoperative grades I (n = 44), II (78), III (83) and IV (19). Healing delay was 55 days for closing and 70 for opening osteotomy. Twenty-nine knees were still painful. Twenty-eight patients were revised and 19 others had complications. After opening wedge osteotomy, scoring was 101/200 and valgus angle was 2 degrees. After closing wedge osteotomy, scoring was 94/200 and valgus angle was 4 degrees. Global results were as follows: very good, 12%; good, 30%; fair, 31%; and poor, 27%. HTO decreases stresses on medial compartments and widens joint space. The average of 5 degrees mechanical valgus at the time of osteotomy seems to be quite effective at the follow-up for at least ten years. Our indications are opening wedge for grades 1-3 and wide varus angle, until the age of between 65-70. Closing wedge is indicated for medium varus in younger patients. PMID:20082076

Benzakour, Thami; Hefti, Abderrazak; Lemseffer, Mohamed; El Ahmadi, Jamal Dine; Bouyarmane, Houssam; Benzakour, Ahmed

2010-02-01

117

Acute glomerulonephritis: a 7 years follow up of children in center of Iran.  

PubMed

Acute glomerulonephritis (AGN) is a type of renal disease which indicates the inflammation of glomerulus and nephrons. This study was carried on 94 children, <15 years old with the diagnosis of AGN who were admitted to Qom and Yazd's hospitals between 2000 and 2006. Data were collected using hospital records on admission, progression notes and outpatient follow up. Among 94 patients, 55.3% were male and 44.6% were female. Mean age of patients was 8.2±2.7 years old. Acute post streptococcal glomerulonephritis (APSGN) was reported in 92.5%, membranoproliferative glomerulonephritis in 4.2%, hemolytic uremic syndrome in 2.1% and IgA nephropathy in 1.06%. There was no significant differences between GN types and gender (P=0.54). Clinical manifestation included edema in 68.8%, oliguria in 36.3%, gross hematuria in 69.1%, HTN in 61.7% and anuria in 1.06%. Microscopic hematuria was detected in all patients. In the time of follow up none of patients had hypertension, 3.1% had proteinuria and 6.3% had microscopic hematuria. APSGN is the most common causes of AGN in Qom and Yazd's children. Early diagnosis and treatment of APSGN may protect children from long term morbidity and mortality and improve quality of life. PMID:21874641

Sepahi, Mohsen Akhavan; Shajari, Ahmad; Shakiba, Mehrdad; Shooshtary, Fatemeh Khalife; Salimi, Mohammad Hossein

2011-01-01

118

Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study  

PubMed Central

Background. End-stage renal disease (ESRD) patients under hemodialysis (HD) have high mortality rate. Inflammation, dyslipidemia, disturbances in erythropoiesis, iron metabolism, endothelial function, and nutritional status have been reported in these patients. Our aim was to identify any significant association of death with these disturbances, by performing a two-year follow-up study. Methods and Results. A large set of data was obtained from 189 HD patients (55.0% male; 66.4 ± 13.9 years old), including hematological data, lipid profile, iron metabolism, nutritional, inflammatory, and endothelial (dys)function markers, and dialysis adequacy. Results. 35 patients (18.5%) died along the follow-up period. Our data showed that the type of vascular access, C-reactive protein (CRP), and triglycerides (TG) are significant predictors of death. The risk of death was higher in patients using central venous catheter (CVC) (Hazard ratio [HR] =3.03, 95% CI = 1.49–6.13), with higher CRP levels (fourth quartile), compared with those with lower levels (first quartile) (HR = 17.3, 95% CI = 2.40–124.9). Patients with higher TG levels (fourth quartile) presented a lower risk of death, compared with those with the lower TG levels (first quartile) (HR = 0.18, 95% CI = 0.05–0.58). Conclusions. The use of CVC, high CRP, and low TG values seem to be independent risk factors for mortality in HD patients.

do Sameiro-Faria, Maria; Costa, Elisio; Mendonca, Denisa; Teixeira, Laetitia; Rocha-Pereira, Petronila; Fernandes, Joao; Kohlova, Michaela; Reis, Flavio; Amado, Leonilde; Bronze-da-Rocha, Elsa; Miranda, Vasco; Quintanilha, Alexandre; Belo, Luis; Santos-Silva, Alice

2013-01-01

119

Management of multiple intrusive luxative injuries: A case report with 7-year follow-up  

PubMed Central

This report presents a case of severe intrusive luxation of multiple anterior teeth in an 11-year-old girl. The teeth were repositioned successfully by endodontic and orthodontic management. The case was monitored for 7 years. Depending on the severity of the injury, different clinical approaches for treatment of intrusive luxation may be used. Despite the variety of treatment modalities, rehabilitation of intruded teeth is always a challenge and a multidisciplinary approach is important to achieve a successful result. In this case, intruded teeth were endodontically treated with multiple calcium hydroxide dressings and repositioned orthodontically. The follow-up of such cases is very important as the repair process after intrusion is complex. After 7 years, no clinical or radiographic pathology was detected.

Thakur, Seema; Thakur, Narbir S.; Gupta, Reecha

2014-01-01

120

Case study of a spinal epidural capillary hemangioma: a 4-year postoperative follow-up.  

PubMed

Study Design?Case study. Objectives?We report the case of a 58-year-old Caucasian man, who presented with a 4-month history of increasing low back pain and gait difficulty. Objective neurologic examination revealed a severe paraparetic symptomatology without any sphincter involvement. Methods?Spinal magnetic resonance imaging (MRI) showed an extradural mass formation situated dorsally at the level of thoracic vertebrae T2 to T4. Results?A laminectomy was performed with total removal of the mass; histology suggested a highly vascularized lesion with lobular architecture, which seems a very rare case, compatible with a capillary hemangioma. Conclusions?A careful follow-up for the next 4 years, including control MRIs every postoperative year, showed a very good neurologic condition of the patient and no recurrence on imaging findings. PMID:24494182

Seferi, Arsen; Alimehmeti, Ridvan; Vyshka, Gentian; Bushati, Teona; Petrela, Mentor

2014-02-01

121

Poor clinical performance of the Wessex porcine heart valve bioprosthesis at nine years' follow up.  

PubMed Central

OBJECTIVE: To assess the long term performance of the Wessex porcine bioprostheses implanted in a consecutive series of patients. DESIGN: A retrospective case series. PATIENTS: Between January 1985 and July 1991, 184 Wessex bioprostheses (78 mitral, 102 aortic, and 4 tricuspid) were implanted in 150 patients. The patients were 55% (83/150) male and 45% (67/150) female; mean age was 60 (SD 10) years. RESULTS: Hospital mortality was 9.3% (14/150). Total follow up was 696 patient-years (mean 4.7 years per patient). Linearised rates (events per 100 patient-years (SEM) for postoperative complications for patients with isolated mitral valve replacement, isolated aortic valve replacement, and multiple valve replacement were, respectively: late mortality: 4.7 (1.6), 3.3 (0.9), and 4.9 (1.9); thromboembolism: 5.8 (1.8), 3.0 (0.9), and 2.8 (1.4); valve thrombosis: 1.0 (0.7), 0.3 (0.3), and 0.7 (0.7); structural failure: 5.8 (1.7), 1.9 (0.7), and 7.1 (2.2). Actuarial freedom from complications at nine years (70% confidence interval) was: late mortality: 61 (9)%, 57 (13)%, and 59 (12)%; thromboembolism and valve thrombosis: 71 (9)%, 79 (6)%, and 81 (8)%; structural failure: 33 (14)%, 50 (16)%, and 12 (14)%; all valve related morbidity/mortality: 31 (10)%, 21 (11)%, and 7 (9)%. Stent fractures appeared in 11 of 17 explanted prostheses; actuarial freedom from stent fracture at nine years was 66 (12)%. CONCLUSIONS: The Wessex bioprosthesis is associated with high thrombogenicity, early structural dysfunction, and a high valve related morbidity/mortality which justifies very close follow up of patients fitted with them. Images

Hurle, A.; Nistal, J. F.; Revuelta, J. M.

1997-01-01

122

Asian-Specific total knee system: 5-14 year follow-up study  

PubMed Central

Background Knee size and body size differ in Asians compared with Caucasians. Nevertheless, many total knee arthroplasty (TKA) prostheses used worldwide are made for Western Caucasian subjects. As a result, an Asian's knee might not fit these prostheses. We studied the Flexible Nichidai Knee (FNK) system, a new model of TKA for Asian patients. The purpose of this report is to investigate the outcomes of this prosthesis retrospectively. Methods We investigated 1055 primary TKAs in 595 patients who underwent FNK for osteoarthritis (OA) in Japan and were followed for > 5 years. The knee score and function score were used for clinical evaluation. We examined the range of motion (ROM) preoperatively and at final follow-up and radiographic assessments. In addition, postoperative complications were investigated. A survivorship analysis was also conducted using two endpoints: revision for any reason and aseptic failure. Results 890 knees in 502 patients were available for study (follow-up rate of 96.0%). The mean follow-up term was 8.3 years (range, 5.0-14.1 years). The knee and function score significantly improved from 41.3 to 90.3 and from 39.1 to 76.2 points, respectively (p < 0.001). The mean ROM in FNK posterior cruciate retaining (CR) type and FNK posterior-stabilized (PS) type ameliorated significantly from 107.8° and 95.6° to 110.7° and 110.4°, respectively (p < 0.01). Ten knees underwent revision surgery (infection in 3 cases, instability in 2, loosening in 2, and non-union of femoral supracondylar fracture, severe pain, and recurrent hemarthrosis in 1 each). The survivorship rate was 99.4% (95% CI, 99.0-99.8) at 5 years (n = 952 patients at risk) and 96.2% (95% CI, 91.9-100) at 12.5 years (n = 49 patients at risk). Conclusion The FNK prosthesis for Asians achieved excellent mid- to long-term survivorship and clinical results.

2011-01-01

123

Prosthetic rehabilitation of hemimandibular hyperplasia: five-year follow-up.  

PubMed

Hemimandibular hyperplasia is a rare asymmetrical mandibular malformation, characterized by enlargement of the condyle, the condylar neck, the ramus, and the body of the mandible. This condition results in laterognathia, dental articulation disorders, and functional defects. Therapy largely depends on the patient's age and the desired esthetic and functional results. This clinical report describes the prosthetic rehabilitation of a 50-year-old woman with hemimandibular hyperplasia. During the diagnostic phase, facial asymmetry was observed, as was the chin midline shifting to the unaffected side and three-dimensional enlargement of one side of the mandible, the condyle, the condylar neck, and the ramus. No biomechanical or functional problems were seen at a five-year follow-up visit, except for physiological wear to the artificial teeth. PMID:20236910

Gokce, Bulent; Ozpinar, Birgul; Ozgur, Levent; Comlekoglu, M Erhan; Aladag, Akin; Akar, Gulcan Coskun

2010-01-01

124

A multidisciplinary approach for ocular rehabilitation following surgical treatment of retinoblastoma: One year follow-up  

PubMed Central

Retinoblastoma is a highly malignant neoplasm. Most of the cases are usually advanced at the time of detection, requiring enucleation to salvage the child's life. Just treating the patient for cancer is not enough; the cosmetic rehabilitation of these patients is equally important and it should always be an integral part of their treatment, to help them re-integrate in the aesthetic conscious society. Rehabilitating such patients require a multidisciplinary approach involving the combined and timely efforts of an ophthalmologist, paediatric oncologist and a skilled maxillofacial prosthodontist. This paper presents a case of 3½-year-old girl who had enucleation of her right eye due to retinoblastoma along with chemotherapy and radiotherapy at the age of 3 years. The patient was recalled regularly for follow-up at 3 month intervals for ophthalmic examinations and she was rehabilitated cosmetically with customised ocular prosthesis during the various stages of her developmental growth.

Aggarwal, Himanshi; Kumar, Pradeep; Singh, Raghuwar D.; Baslas, Varun; Alvi, Habib A.; Jurel, Sunit

2013-01-01

125

Periodontal ligament distraction: esthetics and occlusal stability at the 2-year follow-up.  

PubMed

Dental distraction is an orthodontic tooth movement technique that allows closure of extraction spaces, usually of premolars, in periods from 1 to 3 weeks, by bodily retraction of the canine. This article reports on canine distalization by using a distractor device obtained from a conventional hyrax screw. The patient was an adolescent boy, aged 17 years 9 months, who came to the clinic with the chief complaint of tooth crowding. The clinical examination showed a convex profile, retroclined and protruded maxillary incisors, buccally tipped and protruded mandibular incisors, and a Class I malocclusion. The treatment comprised extractions and rapid canine distraction procedures. Pretreatment, posttreatment, and 2-year follow-up records are shown and demonstrate that dental distraction is a viable alternative of treatment. With this treatment strategy, satisfactory results were obtained without additional anchorage devices, achieving an attractive smile and optimal occlusion. The main considerations about the treatment alternatives and their clinical concerns are discussed. PMID:23561416

Allgayer, Susiane; Rosenbach, Gabriella; Tavares, Carlos Alberto Estevanell; Polido, Waldemar Daudt

2013-04-01

126

Management of skeletal class III malocclusion treated by manifold approach: 5 year follow-up.  

PubMed

The goal of early treatment of Class III malocclusion isfocused on providing a more favourable environment for normal growth and on improving the psychosocial development of the child by improving the facial appearance. Rapid palatal expansion with maxillary protraction and face mask has provided a predictable and effective approach to managing the treatment. We are presenting a case report of a growing Class III treated using maxillary protraction therapy, (Rapid maxillary expansion using bonded RME appliance, to loosen the nasomaxillary sutures and Petit face mask with bonded occlusal splint to unlock the maxilla). With early intervention, patient compliance is much better, most of them achieving overcorrection in less than a year. Close monitoring and follow up was done for 5 years to ensure stability of the treatment, and there was no relapse tendency. PMID:24640076

Tubaki, Roopa; Sharmada, B K; Pai, Sandesh S; Shendre, Shrikanth; Vishwanath, A E

2013-01-01

127

Three-Year Follow Up of Customized Glass Fiber Esthetic Posts  

PubMed Central

Customized glass fiber posts that is well adjusted into the root canal and have mechanical properties similar to those of dentin may be a suitable treatment for severely compromised endodontically treated teeth. This article reports a 3-year follow up of severely damaged endodontically treated teeth restored with unidirectional fiber glass customized post and core system instead of a conventional fiber post. The fabrication of this glass fiber customized post is a simple technique, providing an increased volume of fibers into the root canal, and an adequate polymerization of the post-core system. Over a three-year period, the treatments demonstrated good clinical and radiographic characteristics, with no fracture or loss of the post and/or crown. This technique can be considered effective, less invasive, and suitable for restore endodontically treated teeth.

da Costa, Rogerio Goulart; de Morais, Eduardo Christiano Caregnatto; Leao, Moira Pedroso; Bindo, Marcio Jose Fraxino; Campos, Edson Alves; Correr, Gisele Maria

2011-01-01

128

Predictors of psychosis: a 50-year follow-up of the Lundby population.  

PubMed

Behavioural and neuropsychological vulnerability have been associated with an increased risk of psychosis. We investigated whether certain clusters of premorbid behavioural and personality-related signs and symptoms were predictors of nonaffective and/or affective psychosis and schizophrenia, respectively, in a 50-year follow-up of an unselected general community population. Total population cohorts from the same catchment area in 1947 (n = 2,503) and 1957 (n = 3,215) that had been rated for behavioural items and enduring symptoms were followed up to 1997 regarding first-incidence of DSM-IV nonaffective and/or affective psychosis. Attrition was 1-6%. The influence of the background factors, aggregated in dichotomous variables (predictors), on time to occurrence of nonaffective and/or affective psychosis was assessed by means of Cox regression models. In multivariate models the predictors nervous-tense, blunt-deteriorated, paranoid-schizotypal and tired-distracted were significantly associated with subsequent nonaffective and/or affective psychosis. In simple models, down-semidepressed, sensitive-frail and easily hurt were significantly associated with development of psychosis. When schizophrenia was analysed separately nervous-tense remained significant in the multivariate model, although blunt-deteriorated, paranoid-schizotypal and tired-distracted did not; and abnormal-antisocial reached significance. To conclude, we found some evidence for anxiety-proneness, affective/cognitive blunting, poor concentration, personality cluster-A like traits and interpersonal sensitivity to be associated with general psychosis vulnerability. PMID:19479298

Bogren, Mats; Mattisson, Cecilia; Tambs, Kristian; Horstmann, Vibeke; Munk-Jørgensen, Povl; Nettelbladt, Per

2010-03-01

129

What happens to quality in integrated homecare? A 15-year follow-up study  

PubMed Central

Objectives To explore the impact of structural integration on homecare quality. Methods A case study in an organisation comprising a before–after comparison with baseline and four follow-up measurements during 1994–2009, using interviews with clients (n=66–84) and postal inquiries to relatives (n=73–78) and staff (n=68–136). Results Despite the organisational reform involving extensive mergers of health and social care organisations and cuts in staff and service provision, homecare quality remained at almost the same level throughout the 15-year follow-up. According to the clients, it even slightly improved in some homecare areas. Conclusions The results show that despite the structural integration and cuts in staff and service provision, the quality of homecare remained at a good level. Assuming that the potential confounders did have inhibiting effects, the results suggest that structural integration had a positive impact on homecare quality. To obtain firmer evidence to support this tentative conclusion, further research with a randomised comparison design is needed.

Paljarvi, Soili; Rissanen, Sari; Sinkkonen, Sirkka; Paljarvi, Leo

2011-01-01

130

Multimorbidity and long-term care dependency--a five-year follow-up  

PubMed Central

Background Not only single, but also multiple, chronic conditions are becoming the normal situation rather than the exception in the older generation. While many studies show a correlation between multimorbidity and various health outcomes, the long-term effect on care dependency remains unclear. The objective of this study is to follow up a cohort of older adults for 5 years to estimate the impact of multimorbidity on long-term care dependency. Methods This study is based on claims data from a German health insurance company. We included 115,203 people (mean age: 71.5 years, 41.4% females). To identify chronic diseases and multimorbidity, we used a defined list of 46 chronic conditions based on ICD-10 codes. Multimorbidity was defined as three or more chronic conditions from this list. The main outcome was “time until long-term care dependency”. The follow-up started on January 1st, 2005 and lasted for 5 years until December 31st, 2009. To evaluate differences between those with multimorbidity and those without, we calculated Kaplan–Meier curves and then modeled four distinct Cox proportional hazard regressions including multimorbidity, age and sex, the single chronic conditions, and disease clusters. Results Mean follow-up was 4.5 years. People with multimorbidity had a higher risk of becoming care dependent (HR: 1.85, CI 1.78–1.92). The conditions with the highest risks for long-term care dependency are Parkinson’s disease (HR: 6.40 vs. 2.68) and dementia (HR: 5.70 vs. 2.27). Patients with the multimorbidity pattern “Neuropsychiatric disorders” have a 79% higher risk of care dependency. Conclusions The results should form the basis for future health policy decisions on the treatment of patients with multiple chronic diseases and also show the need to introduce new ways of providing long-term care to this population. A health policy focus on chronic care management as well as the development of guidelines for multimorbidity is crucial to secure health services delivery for the older population.

2014-01-01

131

ALL-EPIPHYSEAL ACL RECONSTRUCTION: A THREE-YEAR FOLLOW-UP  

PubMed Central

Background/Introduction: With an increasing number of pre?adolescents participating in sports, anterior cruciate ligament injuries and resultant reconstruction in the skeletally immature athlete are becoming more common. Many different surgical techniques and rehabilitation protocols have been proposed for the treatment of anterior cruciate ligament (ACL) injuries, but there is a lack of agreement as to which approach results in the best outcome. Rehabilitation protocols have marked variation regarding postoperative weight bearing, immobilization, bracing, and length. Case description: This is a case of a ten year old female who sustained bilateral ACL tears within the period of a year. The purpose of this case report is to describe the early result and subsequent rehabilitation following bilateral physeal?sparing all?epiphyseal ACL reconstructions on a skeletally immature patient with a three?year follow?up. Outcomes: The early post?surgical recovery period on the first injured knee was complicated by knee stiffness requiring manipulation. Following this minor setback, the patient met all physical therapy goals and had no additional complications. The rehabilitation after the second surgery followed a typical course. At three?year follow?up, the patient had grown an additional seven inches, with radiographic evidence of symmetric physeal growth and joint stability. She has returned to playing competitive sports. Discussion and Conclusion: This innovative physeal?sparing technique has huge implications as, historically; the feared complication of growth disturbance and angular deformity from transphyseal ACL reconstruction has complicated the management of ACL injuries in children and pre?adolescents. This case report demonstrates the success of this technique, and the subsequent rehabilitation, as this patient did not experience a reduction in long?term bone growth. Level of Evidence: 5 Case Report

Akinleye, Sheriff D.; Sewick, Amy

2013-01-01

132

6-year follow-up of 84 patients with cartilage defects in the knee  

PubMed Central

Background and purpose The natural history of focal cartilage injury is largely unknown. In this study we investigated 6-year outcomes in patients with arthroscopically verified, focal, full-thickness cartilage injuries of the knee. Methods In a previous report (baseline study) of 993 knee arthroscopies, 98 patients were less than 50 years old at baseline and showed grade 3–4 focal cartilage injury, as assessed with the International Cartilage Repair Society (ICRS) scale. In the present study, 84 of the 98 patients completed follow-ups at median 6.1 (5.3–7.8) years after baseline assessments. At baseline, the patients had undergone different types of cartilage repair (n = 34) or had no treatment or only debridement (n = 64) for their cartilage injury. The follow-up included evaluations with the ICRS knee evaluation form, the Lysholm score, and other knee evaluation tests. 68 patients underwent radiographic assessments with weight bearing. Results Improvements compared to baseline were noted in the average ICRS functional score, visual analog scale (VAS) pain score, and the patients' rating of the function in the affected knee compared to the contra-lateral knee. However, the average ICRS activity level had decreased from baseline. The average Lysholm score was 76 (SD 21). 19 patients had Kellgren-Lawrence grades 2–3 in the affected knee and 6 patients had grades 2–3 in the contralateral knee. There was a statistically significant difference between affected and contralateral knees. Interpretation Patients with arthroscopically diagnosed ICRS grade 3–4 cartilage injuries in the knee may show improvement in knee function over the following 5–8 years, with or without cartilage repair. However, knee function remains substantially affected. Further studies are needed to determine whether cartilage surgery can yield better functional outcomes than non-surgical or less invasive surgical treatments.

2010-01-01

133

A 3-year follow-up study of inpatients with lower limb ulcers: evidence of an obesity paradox?  

PubMed Central

Objectives To determine whether body composition is related to long-term outcomes amongst vascular inpatients with lower limb ulcers. Design Prospective study with 3 years follow-up. Materials and methods Body mass index (BMI), fat, and fat-free mass were measured and associations with readmission to hospital (number, cause, length of stay) and all-cause mortality were explored. Results Thirty patients (22 men, 8 women) participated in the study. Ten patients (33%) had a BMI ? 30 kg/m2. 18/20 (90%) patients with a BMI < 30 kg/m2 and 9/10 (90%) patients with a BMI ? 30 kg/m2 were admitted to hospital in the 3 years of follow-up. Patients with a BMI < 30 kg/m2 were admitted more frequently, earlier and for longer compared to those with BMI ? 30 kg/m2 but these did not reach statistical significance. The 3 year mortality rate for patients with BMI ? 30 kg/m2 was 20% (n = 2/10) compared to 70% (n = 14/20) with a BMI < 30 kg/m2, P = 0.019. Conclusion This preliminary study suggests that higher BMI may have a protective effect against mortality in vascular patients with lower limb ulcers. These findings contradict the universal acceptance that obesity leads to poor health outcomes. Further work is required to confirm these findings and explore some of the potential mechanisms for this effect.

Miller, Michelle; Delaney, Christopher; Penna, Deanna; Liang, Lilian; Thomas, Jolene; Puckridge, Phillip; Spark, James I

2012-01-01

134

Using mortality follow-up of surveys to estimate social inequalities in healthy life years  

PubMed Central

Background The estimation of healthy life years (HLY) by socio-economic status (SES) requires two types of data: the prevalence of activity limitation by SES generally extracted from surveys and mortality rates by SES generally derived from a linkage between the SES information in population databases (census, register) and mortality records. In some situations, no population-wide databases are available to produce mortality rates by SES, and therefore some alternatives must be explored. This paper assesses the validity of calculating HLY by SES using mortality rates derived from a linkage between surveys and mortality records. Methods Two surveys were chosen to explore the validity of the proposed approach: The Belgian Health Interview Survey (HIS) and the Belgian Survey on Income and Living Conditions (SILC). The mortality follow-up of these surveys were used to calculate HLY by educational level at age 25. These HLY were compared with HLY estimates calculated using the mortality follow-up of the 2001 census. The validity of this approach was evaluated against two criteria. First, the HLY calculated using the census and those calculated using the surveys must not be significantly different. Second, survey-based HLY must show significant social inequalities since such inequalities have been consistently reported with census-based HLY. Results Both criteria were met. First, for each educational category, no statistically significant difference was found when comparing census-based and survey-based HLY estimates. For instance, men in the lowest educational category have shown a HLY of 34 years according to the HIS, and while this figure was 35.5 years according to the census, this difference was not statistically significant. Second, the survey-based HLY have shown a significant social gradient. For instance, men in the highest educational category are expected to live 9.5 more HLY than their counterparts in the lowest educational category based on the HIS estimates, compared with 7.3 HLY based on the census estimates. Conclusions This article suggests that using the mortality follow-up of a nationally representative cross-sectional survey is a valid approach to monitor social inequalities in HLY in the absence of population-wide data.

2014-01-01

135

Sodium bicarbonate cotransporter polymorphisms are associated with baseline and 10-year follow-up blood pressures.  

PubMed

The NaHCO3 cotransporter gene (SLC4A5) on chromosome 2 encodes a protein that transports sodium and bicarbonate across the cell membrane and regulates cellular pH. The National Heart, Lung, and Blood Institute Family Blood Pressure Program found linkage of blood pressure-related traits to the chromosomal region containing SLC4A5 and phenotype associations with single nucleotide polymorphisms (SNPs) in this gene. However, the results were inconsistent over various phenotypes and SNPs. Nevertheless, the evidence was strong enough to propose this gene as a blood pressure-related gene. To extend these findings, SLC4A5 SNPs were genotyped in an independent set of 96 Utah pedigrees of 1040 adult subjects at baseline, 760 of whom were followed longitudinally for 10 years. After adjusting for age, gender, body mass index, and polygenic correlations within pedigrees, SNP hcv1137534 was significantly associated with both systolic blood pressure and diastolic blood pressure (DBP) at baseline (unadjusted P=0.009 and P=0.043; respectively) and at 10-year follow-up (P=0.008 and P=0.007; respectively). In secondary tests of association of baseline-stressed blood pressure, hcv1137534 was borderline or significantly associated with DBP change during an isometric handgrip test (P=0.054), DBP change from supine to standing (P=0.020), and DBP change after a 50 degrees tilt (P=0.034). There was no evidence for compensation of abnormal SLC4A5 sodium transport by genotype-specific differences in sodium-lithium countertransport, lithium-potassium cotransport, altered plasma sodium, chloride, or CO2 levels. Therefore, in these Utah pedigrees, the SLC4A5 gene was significantly associated with blood pressure and persisted after 10 years of follow-up. These results additionally confirm the involvement of SLC4A5 with blood pressure control, although the mechanism is still unclear. PMID:16365189

Hunt, Steven C; Xin, Yuanpei; Wu, Lily L; Cawthon, Richard M; Coon, Hilary; Hasstedt, Sandra J; Hopkins, Paul N

2006-03-01

136

Mortality and cancer morbidity of Finnish chlorophenoxy herbicide applicators: an 18-year prospective follow-up.  

PubMed

An 18-year follow-up for mortality and cancer morbidity was conducted in a cohort of 1,909 men who had started spraying chlorophenoxy herbicides (mixture of 2,4-dichlorophenoxyacetic acid [2,4-D] and 2,4,5-trichlorophenoxyacetic acid [2,4,5-T]) in 1955 through 1971. In all, 384 persons had died during the follow-up, and there was a slight deficit in natural deaths (standardized mortality ratio [SMR] 0.84; 95% confidence interval [CI] 0.75-0.94). By contrast, there was a small, nonsignificant increase in accidental and violent deaths. The overall cancer mortality was slightly less than in the general population (SMR 0.83; 95% CI 0.65-1.02), and not a single case of death of non-Hodgkin's lymphomas (NHL) or soft tissue sarcomas (STS) was detected. With regard to cancer morbidity, the incident cases showed a slight deficit compared to the population figure (standardized incidence ratio [SIR] 0.81; 95% CI 0.67-0.97). One case of NHL was found (2.4 expected with 10 years of latency), but not a single case of STS (0.8 expected with 10 years of latency). While our study does not support the contention that spraying of 2,4-D and 2,4,5-T containing herbicides carries any significant risk of cancer, the medium to low statistical power of the study does not allow any far reaching negative conclusions regarding the carcinogenicity of the agents. PMID:7802854

Asp, S; Riihimäki, V; Hernberg, S; Pukkala, E

1994-08-01

137

Longitudinal associations between depressive symptoms and body mass index in a 20-year follow-up.  

PubMed

Objective:Longitudinal studies have rarely investigated changes in depressive symptoms and indicators of obesity simultaneously, although it is often proposed that the positive relationship between depression and obesity is bidirectional. The present study examined the reciprocal nature of the relationship between depressive symptoms and body mass index (BMI) in a 20-year follow-up survey.Methods:Participants of a Finnish cohort study in 1989 at 22 years (N=1656) were followed up at ages 32 (N=1262) and 42 (N=1155) with postal questionnaires. BMI was calculated on the basis of self-reported weight and height, and depressive symptoms were assessed using the short form of the Beck Depression Inventory. Latent growth models (LGM) and cross-lagged autoregressive models were used to determine prospective associations between depressive symptoms and BMI.Results:LGM analyses indicated that men with higher initial levels of depressive symptoms experienced a faster rate of increase in BMI (?=0.20, P<0.01). Among women, change in BMI or depressive symptoms was not predicted by the other construct, but initial levels of BMI and depressive symptoms as well as their rate of change correlated positively with each other (r=0.15 and 0.37, respectively). In cross-lagged models, depressive symptoms at age 32 predicted greater BMI at 42 (?=0.10, P<0.001) among men, whereas women with higher BMI at age 32 were more likely to have more depressive symptoms at 42 (?=0.08, P<0.05).Conclusions:Elevated depressive symptoms predicted weight gain in men, while changes in depressive symptoms and body weight occurred concurrently in women. Tentative evidence showed that women with excess body weight were more likely to have increased symptoms of depression 10 years later. More emphasis should be placed on depressive symptoms in weight control programs as well as on reducing weight-based stigmatization and discrimination in society. PMID:23949617

Konttinen, H; Kiviruusu, O; Huurre, T; Haukkala, A; Aro, H; Marttunen, M

2014-05-01

138

5 Years review of periocular basal cell carcinoma and proposed follow-up protocol  

PubMed Central

Aim (1) To investigate the recurrence of periocular basal cell carcinoma (BCC) reported as completely excised on histology. (2) To identify risks associated with recurrence. (3) To recommend a rational follow-up protocol. Methods This is a cohort study by case note review of consecutive patients undergoing excision of periocular BCC between 2000 and 2006 at University Hospitals of Leicester. All lesions were excised with 3?mm clinical margin and the defect reconstructed only after the excision margin was declared clear. Results A total of 413 episodes of surgical excision were recorded for 270 patients over the 7-year period of 2000–2006. All of them have 5 years follow-up. Mean age 73.7 (±12.5). In all, 67% were nodular BCC and 45.4% located in the lower eyelid. The main outcome measure was the recurrence rate. None of the patients with primary nodular BCC suffered recurrence. The recurrence rate for primary morphoeaform BCC following complete excision is 3.8%. In total, 8.1% of patients had several lesions simultaneously whereas 7.8% patients had BCC in multiple locations subsequently (metachronous). Three patients who had previously recurrent BCC (rBCC) treated elsewhere or not using this method had orbital/lacrimal drainage system involvement requiring exenteration. Conclusion We recommend that patients with a single, completely excised primary solid or nodular BCC can be discharged after one 6-monthly review, although they should be instructed to monitor for the development of further lesions. The incidence of recurrence for primary morphoeaform BCC is 3.8% and for rBCC is 3.6% over 5 years and these patients should stay under review for this period.

Ho, S F; Brown, L; Bamford, M; Sampath, R; Burns, J

2013-01-01

139

New polyethylenes in total hip replacement: A ten- to 12-year follow-up study.  

PubMed

Between 1999 and 2001, 90 patients underwent total hip replacement using the same uncemented acetabular and femoral components with a 28 mm metallic femoral head but with prospective randomisation of the acetabular liner to either Durasul highly cross-linked polyethylene or nitrogen-sterilised Sulene polyethylene. We assessed 83 patients at a minimum follow-up of ten years. Linear penetration of the femoral head was estimated at six weeks, six and 12 months and annually thereafter, using the Dorr method, given the non-spherical shape of the acetabular component. There was no loosening of any component; only one hip in the Sulene group showed proximal femoral osteolysis. The mean penetration of the femoral head at six weeks was 0.08 mm (0.02 to 0.15) for the Durasul group and 0.16 mm (0.05 to 0.28) for the Sulene group (p = 0.001). The mean yearly linear penetration was 64.8% lower for the Durasul group at 0.05 mm/year (sd 0.035) for the Sulene group and 0.02 mm/year (sd 0.016) for the Durasul (p < 0.001). Mean linear femoral head penetration at ten years was 61% less in the Durasul than Sulene group. Highly cross-linked polyethylene gives excellent results at ten years. PMID:23450015

García-Rey, E; García-Cimbrelo, E; Cruz-Pardos, A

2013-03-01

140

Trevor Disease (Hemimelic Epiphyseal Displasia): 12-year Follow-up Case Report and Literature Review  

PubMed Central

Trevor disease or hemimelic epiphyseal dysplasia is a rare skeletal developmental disorder characterized by asymmetric overgrowth of cartilage in the epiphyses. Histologically, it is an epiphysis osteochondroma. The symptom onset occurs primarily during childhood. Males are 3 times more affected than females. The most common symptom is a painless bony mass around the ankle or knee, followed by swelling, restricted range of motion and deformity. Imaging diagnosis is based on plain radiographs, computed tomography scans and magnetic resonance imaging. Treatment depends on the deformities, symptoms, location and amount of epiphysis involvement. Asymptomatic patients require no treatment. When no deformities are identified, simple mass excision is the treatment choice. If the mass causes epiphyses asymmetry, resection must be combined with osteotomies. The present study reports a case of Trevor disease in a female patient with 12-year follow-up. A general review of Trevor disease was also performed.

Baumfeld, DS; Pires, RES; Macedo, BD; Abreu-e-Silva, GMD; Alves, TA; Raduan, FC; Nery, CADS

2014-01-01

141

First year follow-up of extremely low birth weight premature sextuplets: case report.  

PubMed

High order gestation rates have increased in many western countries in the last decades, which is mostly attributable to a contemporaneous increase in maternal age and infertility treatment. Multiple births have been associated with increased maternal and foetal morbidity and mortality during pregnancy and delivery, including the higher risk for spontaneous abortion, preeclampsia, hydramnios, and maternal haemorrhage. A higher frequency of preterm infants and low birth weight infants have also been reported, as well as a higher rate of malformations, abnormal growth, and trauma at delivery, than in singleton pregnancies. We describe herein the case of six ELBW newborns delivered at 27 weeks and their first year follow-up. All the sextuplets survived and did not have extra uterine growth retardation (EUGR) when discharged from hospital. A developmental delay was detected in five infants at 12 months corrected age (CA), but none of them showed cerebral palsy or severe neurosensorial disabilities. PMID:21942612

Orfeo, Luigi; Casani, Anna; Cocca, Francesco; Coletta, Concettina; De Luca, Maria Gabriella; Di Manso, Gaetano; Grappone, Lidia; Pozzi, Nicola; Scoppa, Alessandro

2011-10-01

142

A six year follow-up of three dental alloy restorations with different copper contents.  

PubMed

Class II restorations of three amalgam alloys, with 6%, 12% and 23% copper content, respectively, were evaluated and compared intraindividually during a six year follow-up. In total 10.3% of the restorations were replaced during the test period. The reasons for replacement were bulk fracture (5.6%), tooth fracture (2.4%), marginal ridge fracture (0.8%), and secondary caries (1.6%). The intraindividual ranking of the three alloys, including evaluation of anatomical form, marginal adaptation and secondary caries, showed significantly better results for the two high copper alloys than for the conventional low copper alloy. No difference was seen between the two high copper containing alloys. PMID:1817352

van Dijken, J W

1991-01-01

143

Electroencephalographic features in dravet syndrome: five-year follow-up study in 22 patients.  

PubMed

The aim of the study was to evaluate interictal electroencephalogram features in 22 patients with Dravet syndrome from the onset of the disease through the next 5 years. Electroencephalogram was abnormal in 5 patients (22.7%) at onset, and in 17 (77.3%) at the end of the study. Epileptiform abnormalities (focal, multifocal, or generalized) were seen in 6 patients at the onset and in 14 (27% vs 64%) at the end of the study. Photoparoxysmal response was present in 41% of patients at the end of follow-up. No statistical differences were found between mutated and nonmutated groups regarding evolution of background activity, interictal abnormalities, and presence of photoparoxysmal response. Electroencephalogram findings seemed to be age dependent, variable among different patients, and not influenced by the presence of sodium channel, voltage-gated, type I, alpha subunit (SCN1A) mutation. The lack of specific epileptiform abnormalities contributes to the difficulty of patients' management in Dravet syndrome. PMID:22019839

Specchio, Nicola; Balestri, Martina; Trivisano, Marina; Japaridze, Natia; Striano, Pasquale; Carotenuto, Antonio; Cappelletti, Simona; Specchio, Luigi M; Fusco, Lucia; Vigevano, Federico

2012-04-01

144

Outcomes of a university-based registered nurse refresher course. A 5-year follow-up.  

PubMed

Registered Nurse Refresher Courses are not uncommon in university, community college, and hospital settings. Most are costly to the organization in terms of money and human resources--especially when students choose not to practice once they have completed the course. In this study, the author reports the findings of a survey conducted on graduates of a university-based refresher course during a 5-year period. The issues include a retrospective evaluation of the course, mean age at the time of taking the course, time away from active practice before taking the course, number who returned to the workforce after the course, the number who left the workforce, and identification of respective clinical practice area. Statistical follow-up on the Registered Nurses completing the course and descriptors of personal frustrations, rewards, and overall concerns related to the refresher course are described in this article. PMID:7869136

Purnell, L

1995-01-01

145

Hepatobiliary cystadenoma exhibiting morphologic changes from simple hepatic cyst shown by 11-year follow up imagings  

PubMed Central

Background A long-term follow up case of hepatobiliary cystadenoma originating from simple hepatic cyst is rare. Case presentation We report a case of progressive morphologic changes from simple hepatic cyst to hepatobiliary cystadenoma by 11 – year follow up imaging. A 25-year-old man visited our hospital in 1993 for a simple hepatic cyst. The cyst was located in the left lobe of the liver, was 6 cm in diameter, and did not exhibit calcification, septa or papillary projections. No surgical treatment was performed, although the cyst was observed to gradually enlarge upon subsequent examination. The patient was admitted to our hospital in 2004 due to epigastralgia. Re-examination of the simple hepatic cyst revealed mounting calcification and septa. Abdominal CT on admission revealed a hepatic cyst over 10 cm in diameter and a high-density area within the thickened wall. MRI revealed a mass of low intensity and partly high intensity on a T1-weighted image. Abdominal angiography revealed hypovascular tumor. The serum levels of AST and ALT were elevated slightly, but tumor markers were within normal ranges. Left lobectomy of the liver was performed with diagnosis of hepatobiliary cystadenoma or hepatobiliary cystadenocarcinoma. The resected specimen had a solid component with papillary projections and the cyst was filled with liquid-like muddy bile. Histologically, the inner layer of the cyst was lined with columnar epithelium showing mild grade dysplasia. On the basis of these findings, hepatobiliary cystadenoma was diagnosed. Conclusion We believe this case provides evidence of a simple hepatic cyst gradually changing into hepatobiliary cystadenoma.

Fukunaga, Naoto; Ishikawa, Masashi; Ishikura, Hisashi; Ichimori, Toshihiro; Kimura, Suguru; Sakata, Akihiro; Sato, Koichi; Nagata, Jyunichi; Fujii, Yoshiyuki

2008-01-01

146

Cantilever Transforaminal Lumbar Interbody Fusion for Upper Lumbar Degenerative Diseases (Minimum 2 Years Follow Up)  

PubMed Central

Purpose To evaluate the clinical outcomes of cantilever transforaminal lumbar interbody fusion (c-TLIF) for upper lumbar diseases. Materials and Methods Seventeen patients (11 males, 6 females; mean ± SD age: 62 ± 14 years) who underwent c-TLIF using kidney type spacers between 2002 and 2008 were retrospectively evaluated, at a mean follow-up of 44.1 ± 12.3 months (2 year minimum). The primary diseases studied were disc herniation, ossification of posterior longitudinal ligament (OPLL), degenerative scoliosis, lumbar spinal canal stenosis, spondylolisthesis, and degeneration of adjacent disc after operation. Fusion areas were L1-L2 (5 patients), L2-L3 (9 patients), L1-L3 (1 patient), and L2-L4 (2 patients). Operation time, blood loss, complications, Japanese Orthopaedic Association (JOA) score for back pain, bone union, sagittal alignment change of fusion level, and degeneration of adjacent disc were evaluated. Results JOA score improved significantly after surgery, from 12 ± 2 to 23 ± 3 points (p < 0.01). We also observed significant improvement in sagittal alignment of the fusion levels, from - 1.0 ± 7.4 to 5.2 ± 6.1 degrees (p < 0.01). Bony fusion was obtained in all cases. One patient experienced a subcutaneous infection, which was cured by irrigation. At the final follow-up, three patients showed degenerative changes in adjacent discs, and one showed corrective loss of fusion level. Conclusion c-TLIF is a safe procedure, providing satisfactory results for patients with upper lumbar degenerative diseases.

Hioki, Akira; Hosoe, Hideo; Sugiyama, Seiichi; Suzuki, Naoki; Shimizu, Katsuji

2011-01-01

147

Results of a cemented straight titanium alloy femoral stem after mean follow-up of 13 years  

Microsoft Academic Search

The first consecutive series of 250 implantations of a cemented femoral shaft prosthesis made of titanium alloy (Bicontact®,\\u000a Aesculap, Tuttlingen, Germany) in 239 patients are included in this prospective follow-up study. Average time of follow-up\\u000a evaluation was 12.6 years (range 11.8–13.8 years). At follow-up, 116 patients with 112 hips have died and only two could not\\u000a be located. Follow-up rate was 99.2%

C. Eingartner; S. Piel; K. Weise

2007-01-01

148

Adjuvant radiotherapy and chemotherapy in breast cancer: 30 year follow-up of survival  

PubMed Central

Background The long term outcome (more than 15 years) of adjuvant treatment in patients with primary operable breast cancer has rarely been examined. Methods A randomised clinical trial of radiotherapy, chemotherapy (28 day cycles of cyclophosphamide, methotrexate and 5-fluorouracil) or both on women with primary operable breast cancer (n = 322) was followed-up for a median of 27 years. Results 260 (81%) patients died, 204 (78%) from breast cancer. Cancer specific survival (SE) at 10 years, 20 years and 30 years was 41 (3)%, 34 (3)% and 33 (3)% respectively. Presence of more than 3 involved lymph nodes increased cancer-specific mortality (HR 1.88, 95% CI 1.34-2.63) after adjustment for age, socio-economic deprivation and adjuvant treatment. Both age (HR 1.63, 95% CI 1.19-2.22) and involved lymph nodes (HR 1.59, 95% CI 1.17-2.14) were significant predictors of all-cause mortality after adjustment for other factors. There was no significant difference in all-cause or cancer-specific survival between patients in each of the 3 treatment arms. Conclusions The present study highlights the long term impact of node positive disease but does not indicate that any regimen was associated with significantly better long-term survival.

2010-01-01

149

Long-term deep brain stimulation for essential tremor: 12-year clinicopathologic follow-up.  

PubMed

We describe the clinical course and postmortem pathological findings in a patient with essential tremor (ET) treated with deep brain stimulation (DBS) for 12 years. This 75 year old woman had a 13-year history of progressive ET prior to implantation of bilateral quadripolar DBS electrodes in the region of her ventral intermediate thalamic nuclei in 1996, producing immediate relief of arm tremor. Histopathological examination of the brain, performed 12 years after the initial implantation, demonstrated electrode catheter tracts rimmed by 20-25 micron fibrous sheaths, with multinucleated giant cells and reactive gliosis. Lymphocytic infiltration was seen by L26 immunoreactivity with CD3 (T cells) staining predominating over CD20 (B cells). Cerebellar axonal spheroids and Purkinje cell loss were found. The minimal foreign body reaction and gliosis around the electrodes 12 years after implantation supports the long-term safety of DBS. The case represents the longest reported follow-up with autopsy examination after DBS and confirmed histological changes associated with ET. PMID:20063387

DiLorenzo, Daniel J; Jankovic, Joseph; Simpson, Richard K; Takei, Hidehiro; Powell, Suzanne Z

2010-01-30

150

Early steroid withdrawal in pediatric renal transplant: five years of follow-up.  

PubMed

This prospective, comparative trial investigated the impact on mean change in height standard deviation score (SDS), acute rejection rate, and renal function of early steroid withdrawal in 96 recipients with 5 years of follow-up. Recipients under basiliximab induction and steroid withdrawal (SW: TAC/MMF; n = 55) were compared with a matched steroid control group (SC: TAC/MMF/STEROID, n = 41). SW received steroids until Day 6, SC decreased to 10 mg/m(2) within 2 months post-transplant. Five years after SW, the longitudinal growth (SDS) gain was 1.4 ± 0.4 vs. 1.1 ± 0.3 for SC group (p < 0.02). Height benefits in prepubertal and pubertal status in both groups were demonstrated in the delta growth trends (mixed model; p < 0.01). Biopsy-proven acute rejection in SW was 11% and 17.5%, SC (p: ns). Mean eGFR (ml/min/1.73 m(2)) at 5 years post-transplant was SW 80.6 ± 27.8 vs. 82.6 ± 25.1 for SC (p: ns). The death-censored graft survival rate at 1 and 5 years was 99 and 90% for SW; 98 and 96% for SC (p = ns). PTLD incidence in SW 3.3 vs. 2.5% in SC (p: ns). Five years post-transplant, early steroid withdrawal showed positive impacts on growth, stable renal function without increased acute rejection risk, and PTLD incidence. PMID:21695450

Delucchi, Angela; Valenzuela, Marcela; Lillo, Ana M; Guerrero, Jose Luis; Cano, Francisco; Azocar, Marta; Zambrano, Pedro; Salas, Paulina; Pinto, Viola; Ferrario, Mario; Rodríguez, Jorge; Cavada, Gabriel

2011-12-01

151

Five year follow-up of a prospective cohort of juvenile chronic arthritis with recent onset.  

PubMed

One hundred and fifty children with unsuspected juvenile chronic arthritis (JCA) and a disease duration of 3-6 months entered a prospective study. Diagnosis of JCA could be verified in 107 patients according to the WHO-EULAR criteria. After 5.0 +/- 0.9 years 66 of the 107 patients showed no disease activity, 24 of them for more than 2 years, 23 for less than 2 years without any drug therapy. Nineteen patients were still on NSAIDs and/or long acting drugs, 14 patients with unfavourable morphologic outcome (greater than stage II) and 17 patients with severe functional impairment (greater than or equal to stage III) all belonged to the 41 children with still active disease after 5 years follow-up. The disease course was polyarticular in 10 of the 14 patients with severe radiologic changes and in 14 of the 17 with unfavourable functional results. The wrist joint proved especially vulnerable since 46% of the severe radiologic changes concerned this joint. All 4 children with positive rheumatoid factor followed a polyarticular course with severe radiologic changes (stage greater than II), 3 of them together with unfavourable functional outcome. Risk factors for morphologically and functionally unfavourable course are therefore seen in a still active disease after 5 years, a polyarticular joint involvement and a positive rheumatoid factor. Extra-articular complications concerned chronic iridocyclitis in 7 patients, acute iridocyclitis in 2, amyloidosis in 1 and growth retardation in 2 children. -The prospective study is to be continued. PMID:3690988

Michels, H; Häfner, R; Morhart, R; Schuchmann, L; Truckenbrodt, H

1987-09-01

152

Doping prevalence among preadolescent athletes: a 4-year follow-up  

PubMed Central

Objective To describe the prevalence of doping and its progression in a cohort of preadolescent athletes during a 4?year follow?up. Design and settings Prospective cohort study. Self?questionnaire survey. Participants All of the pupils entering the first year of secondary school (sixth grade) in the Vosges Département (east France) and followed for 4 years. Main outcome measurements Drug use (prohibited substances, tobacco, alcohol, cannabis), intention to use, reported health hazards, perceived drug effectiveness, self?esteem, trait anxiety. Results At the beginning of the study, 1.2% (95% CI 0.8 to 1.6) stated that they had taken doping agents at least once in the preceding 6?months, and this had risen to 3.0% (95% CI 2.3–3.7) 4 years later (p<0.001). Of those who had used doping agents, 4% reported that they had experienced a health problem related to doping, and 44% reported that they had won at least one sports event as a result of using the drug. Use of doping agents is linked to the number of hours of practice per week, intention to use, use of other drugs, self?esteem and trait anxiety. Conclusions The results show that doping does exist in preadolescent athletes who train every day. This fact should to be taken into account in preventive actions.

Laure, P; Binsinger, C

2007-01-01

153

Selective laser trabeculoplasty for primary open angle glaucoma: six-year follow up  

NASA Astrophysics Data System (ADS)

In order to establish the long-term efficacy of selective laser trabeculoplasty for primary open-angle glaucoma [POAG], trabecular meshwork of 34 eyes (21 patients) with POAG was treated with Q-switched frequency doubled Nd-YAG laser with wavelength of 532 nm Coherent Selecta 7000 (SLT). The eyes were divided in two groups: group 1-18 eyes with pigmentation degree in the frontal chamber angle of 1 and 2; group 2-16 eyes with pigmentation degree of 3 and 4. An average of 104 spots on 360 degrees was applied stepwise to the trabecular meshwork of every eye. The treatment and follow up period lasted 6 years. The mean prepoerative intraocular pressure [IOP] in group 1 was 25,5+/-1,5 mmHg, and in group 2-26+/-1 mmHg. During the last visit 6 years after SLT, the mean IOP in group 1 was 18,7+/-1.4 mmHg. Statistically significant decrease of IOP [p<0.001] was observed after SLT by an average of 6,8 mmHg [26.7%]. During the last visit 6 years after SLT in group 2, the mean IOP was 18.8+/-1.2 mmHg. Statistically significant IOP decrase method for POAG treatment and that IOP decrase in treated eyes is preserved for several years.

Koev, Krassimir

2005-04-01

154

Periods of Recovery in Deficit Syndrome Schizophrenia: A 20-Year Multi-follow-up Longitudinal Study  

PubMed Central

Periods of recovery were examined in patients with and without deficit syndrome schizophrenia. Fifty-six patients with schizophrenia were studied, 39 of whom were divided into deficit and nondeficit syndrome schizophrenia subtypes using a proxy method. We also studied 39 nonpsychotic depressive comparison patients. Patients were evaluated as part of the Chicago Follow-up Study, which prospectively examined patients at regular intervals over a 20-year period. Using standardized instruments, patients were evaluated for the deficit syndrome, global recovery, rehospitalization, social dysfunction, occupational disability, and symptom presentation. Recovery was examined at 6 time points measured at 2-, 4.5-, 7.5-, 10-, 15-, and 20-year postindex hospitalization. Cumulatively, over the 20-year period, 13% of patients classified as meeting criteria for the deficit syndrome showed 1 or more 1-year periods of global recovery, in comparison to 63% of nondeficit schizophrenia patients and 77% of depressed patient controls. Results indicate that the deficit syndrome represents a persistently impaired subsample of schizophrenia patients, with continuous social, occupational, and symptom impairment. In contrast, nondeficit syndrome schizophrenia patients showed at least some periods of remission or recovery, with the likelihood of these periods increasing as they became older. Findings provide further support for the validity of the deficit syndrome concept and suggest that deficit status is characterized by a more persistently impaired course of illness and particularly poor long-term prognosis.

Strauss, Gregory P.; Harrow, Martin; Grossman, Linda S.; Rosen, Cherise

2010-01-01

155

Six years follow-up of a penis replantation in a child.  

PubMed

Total amputation of the penis is very rare in a child. This article presents a case of a traumatic penile amputation at the base of the perineum, with scissors, in a 4-year-old child. Six hours after the aggression, the penis was replanted. Three weeks after the intervention, except for skin necrosis, the results were excellent. Six years afterward, this child has done very well from pediatric, psychological, urological, and plastic surgery points of view. Sensibility and erections are present and normal. Longer follow-ups particularly during puberty are necessary. Total amputation of the penis is a very rare accident in a child. Partial lesions are more common, particularly during circumcision. As in adult cases, replantation of the penis in a child needs a clean section by scissors or a knife, a correct conservation of the penis (in ice but without direct contact), and a short period between the lesion and the surgical procedure. All these conditions explain that very few cases are reported in the literature. We present a case of amputation of the penis in a 4-year-old child, with good results 6 years afterward. PMID:18358266

de Lagausie, Pascal; Jehanno, Pascal

2008-03-01

156

Results of revision total hip arthroplasty with Anatomic BR stem: 10-year minimum follow-up.  

PubMed

Twenty cementless total hip revision arthroplasties using Anatomic BR stems were performed in 20 patients. Fourteen patients, with a mean age of 62.6 years (range 41-74 years) at time of revision surgery, were followed retrospectively for a minimum of 10 years (range 11-15 years). Clinical function and radiographic evidence of implant stability were evaluated. Preoperative femoral deficiencies were evaluated radiographically and classified according to Paprosky type as follows: four Type-II, four Type-IIIA, four Type-IIIB, and two Type-IV femurs. Mean preoperative Harris hip score was 46.3 points (range 29-58 points) and improved to 68.8 points (range 45-90 points) at the most recent follow-up examination. Of the 14 patients followed, six had radiographic evidence of subsidence (axial shift of more than 2 mm after revision with long-stem components). Component fixation showed bone ingrowth in three (21%) patients, inconclusive evidence of ingrowth in six (43%) patients, suboptimal but stable fixation in three (21%) patients, and unstable fixation in two (14%) patients. Based on these we results, we conclude that even with circumferential proximal porous coating and improved proximal geometry, nonmodular femoral implant stability remains unpredictable following total hip arthroplasty revision. PMID:21373799

Tsukeoka, Tadashi; Lee, Tae Hyun; Tsuruoka, Hiroaki; Murata, Tadao; Suzuki, Masahiko

2011-10-01

157

Ten-year follow up after laparoscopic Nissen fundoplication for gastroesophageal reflux disease.  

PubMed

Laparoscopic Nissen fundoplication was first undertaken in the early 1990s. Appreciable numbers of patients with 10-year follow up are only now available. This study assesses long-term outcome and durability of outcome after laparoscopic Nissen fundoplication for treatment of gastro-esophageal reflux disease. Since 1991, 829 patients have undergone laparoscopic fundoplications and are prospectively followed. Two hundred thirty-nine patients, 44 per cent male, with a median age of 53 years (+/- 15 standard deviation) underwent laparoscopic Nissen fundoplications at least 10 years ago; 28 (12%) patients were "redo" fundoplications. Before and after fundoplication, among many symptoms, patients scored the frequency and severity of dysphagia, chest pain, vomiting, regurgitation, choking, and heartburn using a Likert scale (0 = never/not bothersome to 10 = always/very bothersome). Symptom scores before versus after fundoplication were compared using a Wilcoxon matched-pairs test. Data are reported as median, mean +/- standard deviation, when appropriate. After fundoplication, length of stay was 2 days, 3 days +/- 4.8. Intra-operative inadvertent events were uncommon and without sequela: 1 esophagotomy, 1 gastrotomy, 3 cardiac dysrhythmias, and 3 CO2 pneumothoraces. Complications after fundoplication included: 1 postpneumonic empyema, 3 urinary retentions, 2 superficial wound infections, 1 urinary tract infection, 1 ileus, and 1 intraabdominal abscess. There were two perioperative deaths; 88 per cent of the patients are still alive. After laparoscopic Nissen fundoplication, frequency and severity scores dramatically improved for all symptoms queried (P < 0.001), especially for heartburn frequency (8, 8 +/- 3.2 versus 2, 3 +/- 2.8, P < 0.001) and severity (10, 8 +/- 2.9 versus 1, 2 +/- 2.5, P < 0.001). Eighty per cent of patients rate their symptoms as almost completely resolved or greatly improved, and 85 per cent note they would again have the laparoscopic fundoplication as a result of analysis of our initial experience, thereby promoting superior outcomes in the future. Nonetheless, follow up at 10 years and beyond of our initial experience documents that laparoscopic fundoplication durably provides high patient satisfaction resulting from long-term amelioration of the frequency and severity of symptoms of gastroesophageal reflux disease. These results promote further application of laparoscopic Nissen fundoplication. PMID:17879678

Cowgill, Sarah M; Gillman, Rachel; Kraemer, Emily; Al-Saadi, Sam; Villadolid, Desiree; Rosemurgy, Alexander

2007-08-01

158

Five-year clinical and angiographic follow-up after intracoronary iridium-192 radiation therapy  

SciTech Connect

Background: Ionizing gamma radiation has been shown to reduce neointimal formation and the incidence of restenosis after balloon angioplasty and stenting in clinical trials. However, the long-term effects of this therapy are unknown. The first cohort of patients to receive intracoronary gamma radiation after balloon angioplasty for the prevention of restenosis have completed a 5-year angiographic and clinical follow-up. The outcome of these patients is presented and discussed. Methods: Twenty-one patients with unstable angina (22 arteries) underwent standard balloon angioplasty. Intracoronary radiation therapy was performed immediately after the intervention using an Iridium-192 source wire hand-delivered to the angioplasty site. All patients were followed clinically and Quantitative Coronary Analysis (QCA) was performed at 6, 24, 36 and 60 months. Results: Target lesion revascularization occurred in six lesions, three of which were total occlusions (two early within 30 days and one occurred at 2 years), and one patient had a myocardial infarction attributable to a nontarget vessel. Serial QCA detected a binary restenosis rate of 28.6% (n=6) at 6 months. The late loss (0.29 mm) and loss index (0.25) remained low at 2, 3 and 5 years. Angiographic complications included four aneurysms (two procedure related and two occurring within 3 months). At 2 years, only one aneurysm increased in size (46 vs. 27 mm{sup 2}); and at 3 and 5 years, all aneurysms remained unchanged. No other angiographic complications were observed. Conclusion: The early clinical and angiographic effects of intracoronary gamma radiation were maintained at 5 years without further increase in the aneurysm formation or apparent new adverse effects related to the radiation therapy between 2 and 5 years.

Condado, Jose A.; Waksman, Ron; Saucedo, Jorge F.; Bhargava, Balram; Lansky, Alexandra J.; Calderas, Carlos; Gurdiel, Orlando; Gonzalez, Juan; Fadoul, Merche; Parra, Bogart; Iturria, Isabel; Amezaga, Bingen

2002-06-01

159

Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI)--5-year follow-up.  

PubMed

Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI) is a new operation procedure using a cell seeded collagen matrix for the treatment of localized full-thickness cartilage defects. A prospective clinical investigation was carried out in order to clarify whether this proves suitable and confirms objective and subjective clinical improvement over a period of up to 5 years after operation. Thirty-eight patients with localised cartilage defects were treated with MACT. Within the context of clinical follow-up, these patients were evaluated for up to 5 years after the intervention. Four different scores (Meyers score, Tegner-Lysholm activity score, Lysholm-Gillquist score, ICRS score) as well as the results of six arthroscopies and biopsies obtained from four patients formed the basis of this study. For 15 patients, 5 or more years had elapsed since the operation at the time this study was completed. It was possible to obtain results 5 years postoperatively from 11 (73.3%) of these 15 patients. Overall, we included 25 patients into the evaluation with a 2-year or longer postoperative period. Five years after transplantation 8 out of 11 patients rated the function of their knee as much better or better than before. Three of the four scores showed significant improvement compared to the preoperative value. One score, the Tegner-Lysholm score showed improvement, which, however, did not prove to be significant. The significantly improved results on three scores after 5 years suggest that MACT represents a suitable but cost-intensive alternative in the treatment of local cartilage defects in the knee. PMID:16632362

Behrens, Peter; Bitter, Thomas; Kurz, Bodo; Russlies, Martin

2006-06-01

160

Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study  

PubMed Central

This is a 12-year follow-up cohort study with 800 people (60–85 years old). The association between lipid disorders and mortality was analysed by Cox proportional hazard adjusted model. All-cause mortality was considered the dependent variable, and lipid disorders as independent variables: total cholesterol (TC) >200 and <170?mg/dl, HDL-c <35 and 40, LDL-c >100 and 130, and triglycerides (TG) >50. An initial analysis of all subjects was performed and a second was carried out after having excluded individuals with a body mass index (BMI) <20?kg/m2 or mortality in ?2 years. The mortality showed a positive association with low TC and a negative association with high TC and high LDL-c. After the exclusion of underweight and premature mortality, there was a positive association only with TC <170?mg/dl (HR = 1.36, CI95%: 1.02–1.82). The data did not show a higher risk with high levels of TC, LDL-c, and TG. However, they showed higher mortality among older adults with low TC.

Cabrera, Marcos Aparecido Sarria; de Andrade, Selma Maffei; Dip, Renata Maciulis

2012-01-01

161

A 15-year follow-up of first unprovoked seizures: a prospective study of 200 children.  

PubMed

Epilepsy is associated with an extended spectrum of behaviour, psychiatric problems, and learning difficulties. The aim of this study was to establish the natural history of children with first unprovoked seizures. We studied prospectively 200 children under the age of 11 years who attended hospital emergency with a first unprovoked seizure. Demographic variables, personal and family history, neurological examination, EEG, psychiatric, and cognitive and educational profiles were analysed. Patients who developed epilepsy were characterised with respect to: time to relapse, remission rate, duration of epilepsy, neuroimaging, aetiology, epileptic syndrome, and therapeutic regimen. These results were compared to data of patients who had a single seizure over a follow-up period of 15 years. Thirty percent of children who had a first unprovoked seizure developed epilepsy. Partial seizure type was a statistically significant variable for the development of epilepsy. An EEG with epileptic abnormalities proved to be the main risk factor for recurrence. Fifteen years later, the group with epilepsy exhibited a 2.6 greater risk of psychiatric and academic comorbidities, compared to the group without epilepsy. PMID:24691297

Pereira, Cristina; Resende, Cristina; Fineza, Isabel; Robalo, Conceição

2014-03-01

162

Pseudoexfoliation and Alzheimer's disease: a population-based 30-year follow-up study.  

PubMed

Purpose:? To determine the effect of pseudoexfoliation (PEX) on the development of Alzheimer's disease (AD) in a population in which PEX is a common finding. The relationship between open-angle glaucoma (OAG) and AD was also studied. Methods:? Predictors of incident AD, including mixed and unspecified dementia, were analysed in a cohort of 679 residents 65-74?years of age, examined in a population survey in the municipality of Tierp, Sweden, 1984-1986. To expand the cohort, participants in other studies in Tierp were enrolled. In this way, the cohort embraced 1123 people, representing more than 15?700 person-years at risk. Medical records were reviewed to identify subjects diagnosed with dementia. Those with a follow-up time shorter than 2?years were excluded from the study. Results:? By the conclusion of the study, in December 2011, 174 new cases of AD, including mixed and unspecified dementia, had been detected, 41 of whom were affected by PEX at baseline. Higher age and female gender were the only predictors identified. No association between PEX and AD was found (hazard ratio 0.98; 95% confidence interval 0.69-1.40). Newly diagnosed OAG at baseline did not increase the risk (hazard ratio 1.09; 95% confidence interval 0.69-1.74). Conclusion:? Pseudoexfoliation is not a predictor of AD. No association was found between OAG and AD. PMID:23879292

Ekström, Curt; Kilander, Lena

2014-06-01

163

Five year follow up of laser in situ keratomileusis for all levels of myopia  

PubMed Central

Aims To assess the long term refractive and visual outcome of patients who have laser in situ keratomileusis (LASIK) surgery. Methods This was a retrospective study of visual and refractive outcome of patients who had LASIK surgery performed in 1998 and 1999. All levels of myopia were included in the study. 49 patients attended for follow up. The main outcome measures were safety, predictability, efficacy, and stability. Postoperative complications and aberrations were also recorded. The mean preoperative spherical equivalent was ?4.85. Results At 2?months postoperatively 67% of eyes were within plus or minus 0.5D of attempted correction with 81% within plus or minus 1.0D. At 5?years postoperatively 60% of eyes were within plus or minus 0.5D of attempted correction with 83% within plus or minus 1.0D. 88% of eyes had a vision of 6/12 or better at 2?months compared to 89% of eyes at 5?years. Best spectacle corrected visual acuity (BSCVA) was unchanged or improved in 51%. No eye lost more than one line of BSCVA. Overall, there was regression towards myopia with a mean change in refraction of ?0.5D over the 5?years. As expected, severely myopic patients regressed more with a mean change of ?1.06D. However, there was a high level of patient satisfaction with the surgery. Conclusion LASIK surgery offers predictable results in terms of refractive and visual outcome with mild regression in refraction over time.

O'Doherty, M; O'Keeffe, M; Kelleher, C

2006-01-01

164

A three-year follow-up of ocular onchocerciasis in an area of vector control*  

PubMed Central

An evaluation of the effects on onchocerciasis of a 3-year period of vector control was undertaken during 1978 in the Onchocerciasis Control Programme area in West Africa. The results revealed that the overall prevalence of ocular onchocerciasis showed only a slight decrease at the follow-up in 1978, but that there was significantly less infection among children in the age group 5-14 years as compared with 1975. There was a total incidence of ocular signs of onchocerciasis of 8.6% over the 3 years, but also a disappearance of those signs in 11.7% of the sample examined. The incidence of severe onchocercal eye manifestations was low, compared with similar areas of uncontrolled transmission. The particularly low incidence of sclerosing keratitis may be associated with the finding of a significantly decreased microfilarial load in the cornea, whereas the number of living microfilariae in the anterior chamber of the eye was apparently unchanged. The incidence of blindness due to onchocerciasis was low and confined to individuals who already presented severe eye manifestations of the disease before the beginning of the vector control campaign.

Thylefors, B.; T?njum, A. M.

1980-01-01

165

Carcinoma in situ of urinary bladder: incidence, treatment and clinical outcomes during ten-year follow-up.  

PubMed

Bladder carcinoma in situ (CIS) is a rare, high-grade intraepithelial neoplasm with a high tendency of progression and unpredictable clinical course. The aim of this study was to evaluate the incidence, treatment and clinical outcome of patients with CIS during a 10-year period. Medical records of 1062 patients with primary bladder cancer and 847 patients with recurrent bladder cancer that underwent tumor resection at Department of Urology, Split University Hospital Center, Split, Croatia, between January 2001 and December 2010, were analyzed. Among all treated patients with primary bladder neoplasms, 51 (4.8%) had CIS. Primary CIS was diagnosed in 18 (1.7%) and concomitant CIS in 33 (3.1%) patients. In the same period, 847 patients with recurrent tumors were treated by transurethral resection (TUR), 12 (1.4%) of them with secondary CIS. Clinical course was followed-up in 15 patients with primary CIS and 21 patients with concomitant (TaT1) CIS. BCG immunotherapy was applied in 12 patients with primary and 17 patients with concomitant CIS. After median follow-up of 50 months, 9 patients with primary CIS had no sign of disease, 4 progressed, 1 had recurrence and 1 died. After median follow-up of 37 months, 13 (62%) patients with concomitant CIS had complete response, 3 progressed (14%), 1 had recurrence (4%) and 4 patients died, however, only 2 (10%) of these due to bladder cancer. Of all patients receiving BCG immunotherapy, 8 (27%) had significant side effects. The incidence and treatment of patients with CIS of urinary bladder in our institution is comparable to other recent literature reports. PMID:23115943

Librenjak, Davor; Novakovi?, Zana Saratlija; Milosti?, Kazimir

2012-06-01

166

Nonsurgical correction of nasal deformity in unilateral complete cleft lip: a 6-year follow-up.  

PubMed

Nasal deformity in unilateral cleft lip and palate patients increases with time, tongue malposition being one of the causes. Some authors have emphasized the role of nasal and adjacent facial musculature as active extrinsic agents. Another cause of alar deformity can be the lack of a proper foundation because of a maxillary hypoplasia in the region of the pyriform foramen. If alar collapse occurs, the septum bends convexly toward the cleft side. Tissues are soft and plastic during the neonatal period. Once the infant is about 3 months of age, it becomes difficult to correct the nasal deformity. Therefore, any resource used from the first day, and mainly during the first 15 days of life, will be useful to prevent the increasing deformity and to avoid the surgical correction. A controlled clinical trial was planned to compare the anthropometric measurements of the nasal region in two series of patients with unilateral complete cleft lip. In the first group, we included 44 patients who came to our clinic during the first 2 days of life and the second group consisted of 47 patients who were more than 15 days of age at the time of the first consultation. To provide control data for the evaluation of the results after 6 years of follow-up in both series of cleft patients, we also included a third group of 48 healthy 6-year-old children. A nasal component added to the occlusal prostheses was only used in the first group up to the time of surgery. The same surgeon performed a Millard II procedure with muscular reposition as described by Delaire in all the patients. Nasal measurements taken with a caliper, obtained directly from plaster models by using surface impressions of the babies, were confirmed by a laser three-dimensional measuring device. The statistical comparison between both series showed a significant increase of the columellar length in the first group. A 6-year follow-up to compare growth and cosmetic results of the nose revealed a better and permanent nasal nostril symmetry and no alar cartilage luxation in the patients who had had the nasal component. These results highlight the importance of the early treatment and allow us to suggest the nasal prostheses as a way to prevent the increasing nasal deformity, to help nasal remodeling, to obtain columellar elongation, and to avoid or decrease the need for primary surgery of the cleft nose. PMID:10456510

Bennun, R D; Perandones, C; Sepliarsky, V A; Chantiri, S N; Aguirre, M I; Dogliotti, P L

1999-09-01

167

Radio-frequency ablation of small renal tumors: minimum follow up of 1 year  

NASA Astrophysics Data System (ADS)

OBJECTIVE: With the increased utility of complex imaging modalities small renal tumors are being diagnosed with rising frequency. We performed radiofrequency ablation to treat tumors less than 4cm in size using a combination of temperature, impedance, ultrasound and laparoscopic guidance. In this article we reviewed the outcome of radiofrequency ablation of renal tumors at one year at our institution. MATERIALS AND METHODS: Over a three-year period 75 patients with a total of 93 renal tumors underwent radiofrequency ablation. Average patient age was 64.5 years with ASA of 2.9. Indications for nephron sparing were imperative in 33 (solitary kidney 21, renal insufficiency 12). Seventeen patients had significant co-morbidities with ASA score of 3 or more and were thought to be poor candidates for nephrectomy or partial nephrectomy. Five were Jehovah's Witness patients. Average tumor size was 3.2 cm (1.5-4.0). 60% of the tumors were exophytic and 40% deep. Radiofrequency ablation was performed via a transperitoneal approach using the single pronged 3cm Cool tip electrode (Radionics Inc). Tumor was isolated laparoscopically. Prior to ablation the lesions were biopsied. Ablation was performed using both laparoscopic and real-time ultrasound imaging of the boarders of the tumor. During ablation impedance and temperature monitoring was performed. For each tumor two separate ablations were performed at perpendicular angles, the first ablation was for 6 minutes and the second for 3 minutes. The center and periphery of the tumor was monitored to insure that the temperature rose above 70 degrees Celsius. Patients were followed at three-month intervals with triple phase CT scan or MRI to evaluate efficacy of the ablation. Our criteria for recurrent tumor were growth or enhancement of the lesion. RESULTS: Average operative time was 109 minutes with and average EBL of <25cc. Mean hospital stay was 1.4 days. At average follow up of 19.2 months (range 2-24), one lesion showed evidence of tumor recurrence which was corrected surgically. Two masses did show some mild enhancement on CT 6 months post operatively, biopsies showed no evidence of tumor with fibrosis. Of the patients with follow up of greater than 12 months 75% had decreasing size of the lesion, 25% had no change in size. No complications were seen. CONCLUSIONS: Radiofrequency ablation of renal tumors is a feasible alternative for patients that have imperative indication for nephron sparing surgery or those that have significant co-morbidities. The procedure is expedient, efficacious and carries minimal morbidity. It is of extreme importance to follow these patients closely with imaging of the lesion on a frequent basis.

Patel, Vipul; Thaly, Rahul; Shah, Ketul

2007-03-01

168

Nucleoplasty in the Treatment of Lumbar Diskogenic Back Pain: One Year Follow-Up  

SciTech Connect

Purpose. The spine is an important source of pain and disability, affecting two thirds of adults at some time in their lives. Treatment in these patients is mainly conservative medical management, based on medication, physical therapy, behavioral management, and psychotherapy, surgery being limited to elective cases with neurologic deficits. This study was carried out to evaluate the efficacy of percutaneous nucleoplasty in patients affected by painful diskal protrusions and contained herniations. Methods. From February 2004 to October 2005, 72 patients (48 men, 24 women; mean age 48 years) affected by lumbar disk herniation were treated with nucleoplasty coblation. All patients were evaluated clinically and with radiography and MRI in order to confirm the presence of lumbalgic and/or sciatalgic pain, in the absence of major neurologic deficit and with lack of response after 6 weeks of conservative management. Results. Average preprocedural pain level for all patients was 8.2 (on a visual analog scale of 1 to 10), while the average pain level at 12 months follow-up was 4.1. At the 1 year evaluation, 79% of patients demonstrated a statistically significant improvement in numeric pain scores (p < 0.01): 17% (12 patients) were completely satisfied with complete resolution of symptoms, and 62% (43 patients) obtained a good result. Conclusion. Our data indicate that nucleoplasty coblation is a promising treatment option for patients with symptomatic disk protrusion and herniation who present with lumbalgic and/or sciatalgic pain, have failed conservative therapies, and are not considered candidates for open surgery.

Masala, Salvatore, E-mail: salva.masala@tiscali.it; Massari, Francesco; Fabiano, Sebastiano; Ursone, Antonio; Fiori, Roberto [University of Rome 'Tor Vergata', Department of Diagnostic Imaging and Interventional Radiology (Italy); Pastore, Francesco [University of Rome 'Tor Vergata', Department of Neurosurgery (Italy); Simonetti, Giovanni [University of Rome 'Tor Vergata', Department of Diagnostic Imaging and Interventional Radiology (Italy)

2007-06-15

169

[Four year follow-up of social adjustment of a cohort of schizophrenic patients].  

PubMed

Sixty-seven first episode schizophrenic patients (PSE-Catego criteria) have been included in this study in order to evaluate their prognosis and the factors predictive of their evolution. Potential predictive factors consisted of anamnestic and demographic data, scores on the Disability Assessment Schedule (DAS-WHO) and relatives' Expressed Emotion index (EE), measured by the Camberwell Family Interview (CFI). The outcome was assessed monthly by the Global Assessment Scale (GAS/DSM III-R). At four years, 39 patients (58%) were still being followed. 33% of the patients presented a good evolution (EGF > or = 51) and 67% of the patients a bad evolution (EGF < 51). Four factors predictive of the psychosocial adaptation were extracted using regression analysis: premorbid psychosocial evolution, EE, sex and psychiatric family history. These 4 factors predicted correctly 85% of cases. Moreover, the monthly follow-up of these patients pointed to three types of evolution: the patients presenting a good and stable evolution (22%), those presenting a bad and stable evolution (33%) and those presenting an oscillating evolution which fluctuated between good and bad periods (44%). However, no predictive factors of the psychosocial adaptation of these oscillating patients could be identified through the statistical analysis. These results take all their importance regarding the treatment of schizophrenic patients, for whom the therapeutic plans which have to be settled should take into account their prognosis in the most precise manner. Moreover, the predictive value of EE on psychosocial adaptation for a 4 years period is confirmed. PMID:7781589

Huguelet, P; Zabala, I; Cruciani, G; Binyet, S; Favre, S; Gonzalez, C; Ferrero, F

1995-01-01

170

Oral Cancer Screening at Workplace in India--One-year Follow-up  

PubMed Central

Background: Oral cancer remains the commonest form of cancer and cancer-related deaths among Indian males due to popularity of avoidable risk factors such as tobacco and alcohol use. A workplace oral cancer screening and tobacco cessation study was commenced on World No Tobacco Day 2007 at a chemical industry in rural Maharashtra. Aims: The objectives were to screen the employees for oral neoplasia and to correlate it with their tobacco consumption pattern. In addition, the objective was to provide tobacco cessation services at the workplace. Materials and Methods: This is an interventional cohort study among 104 employees of a chemical industrial unit in rural Maharashtra. Naked eye examination of the oral cavity was performed for all employees by a doctor irrespective of the tobacco habits at the beginning and at the end of 1 year. In between, the tobacco users were regularly examined during each follow-up. Statistical analysis used: Through personal interviews of the participants, data were manually recorded and were transferred to electronic data base. Data analysis was conducted in STATA™ 8.2 on intention to treat basis. Results and Conclusions: Among the 104 employees, 50 (48.08%) were current tobacco users at the beginning of the program. Oral precancers were seen exclusively among 20 (40%) tobacco users. After 1 year of workplace tobacco cessation intervention, 80% of oral precancers regressed. This shows that screening of the oral cavity at the workplace is effective when combined with tobacco cessation.

Uplap, PA; Mishra, GA; Majumdar, P; Gupta, SD; Rane, PS; Sadalge, PK; Avasare, AM; Goswami, SS; Dhar, VA; Shastri, SS

2011-01-01

171

Severity of coronary atherosclerosis and stroke incidence in 7-year follow-up.  

PubMed

The purpose of this prospective study was to investigate the association between the severity of coronary atherosclerosis in angiography and the risk of stroke in symptomatic coronary artery disease (CAD) patients without atrial fibrillation or atrial flutter. Associations between stroke and coronary artery disease were examined in 1,183 subjects without a history of stroke and who were referred for diagnostic coronary angiography. Association between stoke and coronary artery disease was determined using the COX proportional hazard regression model. During the follow-up period (mean 6.7 years), 50 strokes occurred. In the group with strokes there was a higher prevalence of multi-vessel coronary artery disease (62 vs. 46 %, p < 0.01). In the COX proportional hazard regression model, multi-vessel CAD was significantly associated with the stroke hazard ratio (HR) of 1.8 (CI 1.03-3.43), determined from a 7-year period of observation. Symptomatic patients with multi-vessel CAD are thus at a high risk of stroke development. PMID:23512577

Sobiczewski, Wojciech; Wirtwein, Marcin; Trybala, Ewelina; Gruchala, Marcin

2013-07-01

172

One-year follow-up of Chinese people with spinal cord injury: A preliminary study  

PubMed Central

Background A tertiary spinal cord injury (SCI) center was established in the northern region of Hong Kong, China and a multidisciplinary SCI rehabilitation program was developed to reintegrate patients into the community. Objective To investigate functional outcomes for Chinese people with SCI across a 1-year period. Design Longitudinal prospective design. Methods Thirty community-dwelling participants with traumatic SCI were recruited. Functional status was measured using functional independence measure (FIM) on admission, upon discharge, 1-month, 3-month, 6-month, and 1-year post-discharge. Information on use of assistive devices and life role were also obtained. Results Twenty-three (76.67%) participants were men. Seventeen participants (10 with tetraplegia and 7 with paraplegia) were classified ASIA A, B, or C; 13 (7 with tetraplegia and 6 with paraplegia) were classified as ASIA D. Significant differences in FIM motor scores were only found between the tetraplegia group and three other diagnostic groups using Bonferroni post-hoc tests of repeated measure ANOVA (analysis of variance) (P < 0.05). Longitudinally, contrast tests of repeated measure ANOVA showed significant differences during the hospitalization period for all diagnostic groups. People in the ASIA D group showed significant functional improvement even after 1-year post-discharge (P < 0.05). At 1-year post-discharge, only two participants were engaged in either remunerative employment or academic pursuit. Conclusion Despite functional status improvement, few people with traumatic SCI were re-engaged in productive life role 1 year after discharge. Studies with longer follow-up would be beneficial.

Chan, Sam Chi Chung; Chan, Alice Po Shan

2013-01-01

173

Treatment Outcomes and Mediators of Parent Management Training: A One-Year Follow-Up of Children with Conduct Problems  

ERIC Educational Resources Information Center

This effectiveness study presents the results of a 1-year follow-up of a randomized controlled trial of Parent Management Training. Families of 112 Norwegian girls and boys with clinic-level conduct problems participated, and 75 (67%) families were retained at follow-up. Children ranged in age from 4 to 12 at intake (M = 8.44). Families randomized…

Hagen, Kristine Amlund; Ogden, Terje; Bjornebekk, Gunnar

2011-01-01

174

Asperger Syndrome and Autism: A Comparative Longitudinal Follow-Up Study More than 5 Years after Original Diagnosis  

ERIC Educational Resources Information Center

Prospective follow-up study of 70 males with Asperger syndrome (AS), and 70 males with autism more than 5 years after original diagnosis. Instruments used at follow-up included overall clinical assessment, the Diagnostic Interview for Social and Communication Disorders, Wechsler Intelligence Scales, Vineland Adaptive Behavior Scales, and Global…

Cederlund, Mats; Hagberg, Bibbi; Billstedt, Eva; Gillberg, I. Carina; Gillberg, Christopher

2008-01-01

175

Prognostic significance of transient myocardial ischaemia after first acute myocardial infarction: five year follow up study.  

PubMed Central

OBJECTIVE--To assess the five year prognostic significance of transient myocardial ischaemia on ambulatory monitoring after a first acute myocardial infarction, and to compare the diagnostic and long term prognostic value of ambulatory ST segment monitoring, maximal exercise testing, and echocardiography in patients with documented ischaemic heart disease. DESIGN--Prospective study. SETTING--Cardiology department of a teaching hospital. PATIENTS--123 consecutive men aged under 70 who were able to perform predischarge maximal exercise testing. INTERVENTIONS--Echocardiography two days before discharge (left ventricular ejection fraction), maximal bicycle ergometric testing one day before discharge (ST segment depression, angina, blood pressure, heart rate), and ambulatory ST segment monitoring (transient myocardial ischaemia) started at hospital discharge a mean of 11 (SD 5) days after infarction. MAIN OUTCOME MEASURES--Relation of ambulatory ST segment depression, exercise test variables, and left ventricular ejection fraction to subsequent objective (cardiac death or myocardial infarction) or subjective (need for coronary revascularisation) events. RESULTS--23 of the 123 patients had episodes of transient ST segment depression, of which 98% were silent. Over a mean of 5 (range 4 to 6) years of follow up, patients with ambulatory ischaemia were no more likely to have objective end points than patients without ischaemic episodes. If, however, subjective events were included an association between transient ST segment depression and an adverse long term outcome was found (Kaplan-Meier analysis; P = 0.004). The presence of exercise induced angina identified a similar proportion of patients with a poor prognosis (Kaplan-Meier analysis; P < 0.004). Both exertional angina and ambulatory ST segment depression had high specificity but poor sensitivity. The presence of exercise induced ST segment depression was of no value in predicting combined cardiac events. Indeed, patients without exertional ST segment depression were at increased risk of future objective end points (Kaplan-Meier analysis; P < 0.0045). These findings may be explained in part by a higher prevalence of left ventricular dysfunction in patients without ischaemic changes in the exercise electrocardiogram (P < 0.05). CONCLUSION--There seem to be limited reasons to perform ambulatory ST segment monitoring in survivors of a first myocardial infarction who can perform exercise tests before discharge. Patients at high risk of future myocardial infarction or death from cardiac causes are not identified. Ambulatory monitoring and exertional angina distinguish a small subset of patients who will develop severe angina pectoris demanding coronary revascularisation during follow up. Patients without exercise induced ST segment depression comprise a high risk subgroup in terms of subsequent objective end points. The role of ambulatory ST segment monitoring performed in unselected patients immediately after infarction when risk is maximal remains to be clarified.

Mickley, H.; Nielsen, J. R.; Berning, J.; Junker, A.; M?ller, M.

1995-01-01

176

Long term results of anterior cruciate ligament reconstruction with iliotibial tract: 6-, 13-, and 24-year longitudinal follow-up.  

PubMed

Many studies have reported successful outcomes less than 10 years after anterior cruciate ligament (ACL) reconstruction. However, longer-term outcomes have not been analyzed. We assessd outcomes 24 years after anterior cruciate ligament reconstruction with iliotibial tract and compared them with shorter-term results in the same patients. Between 1979 and 1981, 45 patients underwent combined intra- and extra-articular ACL reconstruction with iliotibial tract. Follow-up evaluations of these patients were performed at 6, 13, and 24 years after surgery, which included manual and instrumental laxity testing, functional assessments, and radiography. Twenty-six (60%) patients of the original ACL reconstruction cohort participated in all three follow-up assessments. Three patients had undergone meniscectomy prior to ACL reconstruction and 18 underwent meniscectomy together with ACL reconstruction. Eleven patients underwent subsequent meniscectomy. The mean Lysholm score was 96.2, 93.8, and 87.8 at 6-, 13-, and 24-year follow-up, respectively. A significant decrease in mean Lysholm score was found between 13- and 24-year follow-up. The mean KT-1000 side-to-side difference was 3.5 mm at 24-year follow-up. Overall knee laxity did not change significantly during the follow-up period. At 24-year follow-up, 17 (71%) patients had moderate or severe degenerative changes on radiographs although about 50% of the patients participated in regular sports activities and no patient required regular clinical intervention. PMID:16845548

Yamaguchi, Satoshi; Sasho, Takahisa; Tsuchiya, Akihiro; Wada, Yuichi; Moriya, Hideshige

2006-11-01

177

To What Extent is Research Utilized? A Ten-Year Follow-Up Study  

ERIC Educational Resources Information Center

Survey procedures in the follow-up study included notes in rehabilitation journals, questionnaires to persons requesting information on the Scale, and a literature search. Most informative results came from the questionnaire responses. (EA)

Bolton, Brian; Soloff, Asher

1973-01-01

178

Clinical implications of alpha-fetoprotein in liver cirrhosis: five-year follow-up study.  

PubMed

The level of alpha-fetoprotein (AFP) was estimated by radioimmunoassay or passive hemagglutination method in a series of 159 patients with liver cirrhosis, and the incidence of serum hepatitis B antigen, histopathologic features of the liver, incidence of development of hepatocellular carcinoma (HCC) and mortality in AFP-positive cases were studied. Approximately 40 per cent of the patients had an AFP level higher than 20 ng/per ml, and all the elevations of AFP over 100 ng per ml were transient. In contrast, patients who developed HCC during the course of the disease always exhibited an increasing value of AFP. The seropositivity for AFP was significantly related to the presence of serum hepatitis B surface antigen and also to liver cell dysplasia as well as to thickening of the liver cell plates. As compared with a group of AFP-negative cases, the AFP-positive group showed a higher incidence of development of HCC and poorer prognosis over a five-year follow-up period. The data obtained suggested that increased AFP-production in patients with liver cirrhosis might reflect, largely an abnormal or altered liver cell regeneration, probably associated with hepatitis B virus, and that patients with transiently elevated AFP values might be at greater risk for the development of HCC. PMID:6161869

Harada, T; Shigeta, K; Noda, K; Fukumoto, Y; Nishimura, H; Mizuta, M; Takemoto, T

1980-06-01

179

Arthroscopic hemitrapeziectomy for first carpometacarpal arthritis: results at 7-year follow-up.  

PubMed

The purpose of this study was to determine the outcome of arthroscopic hemitrapeziectomy combined with thermal capsular plication and temporary K-wire fixation in patients with painful thumb basal joint due to either osteoarthritis or posttraumatic arthritis. There were 18 thumbs that were evaluated in this retrospective study of arthroscopic hemitrapeziectomy of the distal trapezium in addition to a pancapsular thermal shrinkage at an average of 7.6-year follow-up. No patient has required further surgery. A subjective improvement in pain, pinch activities, strength, and range of motion (ROM) was noted in all patients, and no patient had further surgery on their thumb. On exam, no patient had a first carpal-metacarpal grind or laxity. Total ROM of the thumb axis decreased by 20%, but all patients could oppose to the fifth finger. Grip strength remained unchanged, key pinch improved from 8 to 11 lbs, and tip pinch improved from 4 to 5 lbs. Radiographs showed a metacarpal subsidence of 1.8 mm (0-4 mm). Four complications were noted: two cases of dorsal radial nerve neuritis, one rupture of the flexor pollicis longus, and one prolonged hematoma. Results demonstrate that arthroscopic hemitrapeziectomy and capsular shrinkage for first carpometacarpal arthritis is an effective technique that provides high patient satisfaction, a functional pain-free thumb, and a reliable rate of return to activity. PMID:18820976

Hofmeister, Eric P; Leak, Robert S; Culp, Randall W; Osterman, A Lee

2009-03-01

180

Intensive voice treatment (LSVT(R)) for patients with Parkinson's disease: a 2 year follow up  

PubMed Central

OBJECTIVES—To assess long term (24 months) effects of the Lee Silverman voice treatment (LSVT®), a method designed to improve vocal function in patients with Parkinson's disease.?METHODS—Thirty three patients with idiopathic Parkinson's disease were stratified and randomly assigned to two treatment groups. One group received the LSVT®, which emphasises high phonatory-respiratory effort. The other group received respiratory therapy (RET), which emphasises high respiratory effort alone. Patients in both treatment groups sustained vowel phonation, read a passage, and produced a monologue under identical conditions before, immediately after, and 24 months after speech treatment. Change in vocal function was measured by means of acoustic analyses of voice loudness (measured as sound pressure level, or SPL) and inflection in voice fundamental frequency (measured in terms of semitone standard deviation, or STSD).?RESULTS—The LSVT® was significantly more effective than the RET in improving (increasing) SPL and STSD immediately post-treatment and maintaining those improvements at 2 year follow up. ?CONCLUSIONS—The findings provide evidence for the efficacy of the LSVT® as well as the long term maintenance of these effects in the treatment of voice and speech disorders in patients with idiopathic Parkinson's disease.??

Ramig, L; Sapir, S; Countryman, S; Pawlas, A; O'Brien, C; Hoehn, M; Thompson, L

2001-01-01

181

Dual-mobility cup and cemented femoral component: 6 year follow-up results.  

PubMed

Use of a dual-mobility acetabular cup is associated with a lower risk of dislocation compared with conventional hip implants. The seleXys® DS acetabular cup combines the advantages of Charnley low-friction arthroplasty with those of dual mobility. We performed a non-randomised, prospective study of patients receiving primary hip arthroplasty, including an uncemented seleXys® DS dual-mobility acetabular cup with hydroxyapatite coating (Mathys AG, Bettlach, Switzerland) and a cemented femoral component (Stallion femoral stem Groupe Lepine, Lyon, France). The objective of the study was to evaluate longevity of the implant and the risk of dislocation. All operations were performed by a single surgeon using a posterior approach, with patients lying in the lateral decubitus position. The stem had a modular head diameter of 22.2 mm and was cemented in all patients. A total of 53 patients were studied, and the median duration of follow-up was 78.9 months. Implant survival 6 years after surgery was 98.4% (n=47; 95% CI: 89.3-99.8). There was one revision for sepsis 29 months after surgery, and one dislocation. The results of this study appear to demonstrate excellent implant survival and a low rate of dislocation using the chosen implants. PMID:22117262

Prudhon, Jean Louis

2011-01-01

182

Involvement in bullying and suicidal ideation in middle adolescence: a 2-year follow-up study.  

PubMed

The objective of the study was to ascertain whether involvement in bullying increases the risk for subsequent suicidal ideation. A total of 2,070 Finnish girls and boys aged 15 were surveyed in the ninth grade (age 15) in schools, and followed upyears later in the Adolescent Mental Health Cohort Study. Involvement in bullying was elicited at age 15 by two questions focusing on being a bully and being a victim of bullying. Suicidal ideation was elicited by one item of the short Beck Depression Inventory at age 17. Baseline depressive symptoms and externalizing symptoms, age and sex were controlled for. Statistical analyses were carried out using cross-tabulations with Chi-square/Fisher's exact test and logistic regression. Suicidal ideation at age 17 was 3-4 times more prevalent among those who had been involved in bullying at age 15 than among those not involved. Suicidal ideation at age 17 was most prevalent among former victims of bullying. Being a victim of bullying at age 15 continued to predict subsequent suicidal ideation when depressive and externalizing symptoms were controlled for. Being a bully at age 15 also persisted as borderline significantly predictive of suicidal ideation when baseline symptoms were controlled for. Findings indicate adolescent victims and perpetrators of bullying alike are at long-term risk for suicidal ideation. PMID:23053774

Heikkilä, Hanna-Kaisa; Väänänen, Juha; Helminen, Mika; Fröjd, Sari; Marttunen, Mauri; Kaltiala-Heino, Riittakerttu

2013-02-01

183

Two year follow up of pulmonary function values among welders in New Zealand  

PubMed Central

OBJECTIVES: To examine whether welding is a risk factor for an accelerated decline in pulmonary function. METHODS: 2 Year follow up of pulmonary function and respiratory symptoms among 54 welders and 38 non- welders in eight New Zealand welding sites. RESULTS: There were no significant differences in age, height, smoking habits, ethnicity, or total time in industrial work between welders and non-welders. No overall differences were noted in the changes of pulmonary function variables between the two study groups. However, when the comparison was restricted to smokers, welders had a significantly greater (p = 0.02) annual decline (88.8 ml) in FEV1 than non-welders, who had a slight non-significant annual increase (34.2 ml). Also, welders without respiratory protection or local exhaust ventilation while welding had a greater annual decline both in forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) than welders with protection (p = 0.001 and 0.04, respectively). Among welders a significant association was found between the acute across shift change and the annual decline in FEV1. Chronic bronchitis was more common among welders (24%) than non-welders (5%). Only one welder (2%) but eight non- welders (21%) reported having asthma. CONCLUSIONS: Welders who smoked and welders working without local exhaust ventilation or respiratory protection have an increased risk of accelerated decline in FEV1.  

Erkinjuntti-Pekka..., R.; Slater, T.; Cheng, S.; Fishwick, D.; Bradshaw, L.; Kimbell-, D; Dronfield, L.; Pearce, N.

1999-01-01

184

Rheumatic heart disease: 15 years of clinical and immunological follow-up  

PubMed Central

Rheumatic fever (RF) is a sequel of group A streptococcal throat infection and occurs in untreated susceptible children. Rheumatic heart disease (RHD), the major sequel of RF, occurs in 30%–45% of RF patients. RF is still considered endemic in some regions of Brazil and is responsible for approximately 90% of early childhood valvular surgery in the country. In this study, we present a 15-year clinical follow-up of 25 children who underwent surgical valvular repair. Histopathological and immunological features of heart tissue lesions of RHD patients were also evaluated. The patients presented severe forms of RHD with congestive symptoms at a very young age. Many of them had surgery at the acute phase of RF. Histological analysis showed the presence of dense valvular inflammatory infiltrates and Aschoff nodules in the myocardium of 21% of acute RHD patients. Infiltrating T-cells were mainly CD4+ in heart tissue biopsies of patients with rheumatic activity. In addition, CD4+ and CD8+ infiltrating T-cell clones recognized streptococcal M peptides and cardiac tissue proteins. These findings may open the possibilities of new ways of immunotherapy. In addition, we demonstrated that the surgical procedure during acute phase of the disease improved the quality of life of young RHD patients.

Sampaio, Roney O; Fae, Kellen C; Demarchi, Lea MF; Pomerantzeff, Pablo MA; Aiello, Vera D; Spina, Guilherme S; Tanaka, Ana C; Oshiro, Sandra E; Grinberg, Max; Kalil, Jorge; Guilherme, Luiza

2007-01-01

185

Surgical treatment of spondylodiscitis in the cervical spine: a minimum 2-year follow-up.  

PubMed

Cervical spine spondylodiscitis is a rare, but serious manifestation of spinal infection. We present a retrospective study of 20 consecutive patients between 01/1994 and 12/1999 treated because of cervical spondylodiscitis. Mean age at the time of treatment was 59.7 (range 34-81) years, nine of them female. In all cases, diagnosis had been established with a delay. All patients in this series underwent surgery such as radical debridement, decompression if necessary, autologous bone grafting and instrumentation. Surgery was indicated if a neurological deficit, symptoms of sepsis, epidural abscess formation with consecutive stenosis, instability or severe deformity were present. Postoperative antibiotic therapy was carried out for 8-12 weeks. Follow-up examinations were performed a mean of 37 (range 24-63) months after surgery. Healing of the inflammation was confirmed in all cases by laboratory, clinical and radiological parameters. Spondylodesis was controlled radiologically and could be achieved in all cases. One case showed a 15 degrees kyphotic angle in the proximal adjacent segment. Spontaneous bony bridging of the proximal adjacent segment was observed in one patient. In the other cases the adjacent segments radiologically showed neither fusion nor infection related changes. Preoperative neurological deficits improved in all cases. Residual neurological deficits persisted in three of eight cases. The results indicate that spondylodiscitis in cervical spine should be treated early and aggressive to avoid local and systemic complications. PMID:16868782

Heyde, Christoph E; Boehm, Heinrich; El Saghir, Hesham; Tschöke, Sven K; Kayser, Ralph

2006-09-01

186

Fourteen years follow up after Lisfranc fracture-dislocation: functional and radiological results.  

PubMed

Injuries to the Lisfranc joint have a high potential for chronic disability. Posttraumatic arthritis remains the most common complication but not all patients who develop degenerative radiographic changes are symptomatic. A cohort of 32 patients with a Lisfranc fracture dislocation was reviewed. Initial reduction and secondary displacement were measured by the Myerson scale. Radiographic evidence of osteoarthritis (OA) was also investigated. Long-term radiographical data were classified as good, fair or poor results. Functional outcome was measured using several different scales. Mean follow up was 14 years. Seventeen patients with anatomic close reduction but instability were treated with closed reduction and K-wire fixation followed by cast immobilisation. Eight patients with stable anatomic close reduction were treated with closed reduction and cast. Seven patients with unacceptable closed reduction were treated with open reduction and K-wire stabilisation. The analysis of radiological long-term data showed 15 patients with good results, 8 with fair results and 9 with poor results. Final mean AOFAS score was 91.7/100. There was no statistically significant difference between overall PFS scores and different type of treatment, Hardcastle long-term radiological scores or Hardcastle type of fracture (p >0.05). Overall, there was a poor association between the extent of radiological arthritis and clinical scores. We advocate that for the evaluation of long-term outcome of these injuries functional parameters should be the focus of assessment, instead of radiological changes. PMID:23622999

Marín-Peña, Oliver R; Viloria Recio, Fernando; Sanz Gómez, Tomas; Larrainzar Garijo, Ricardo

2012-12-01

187

Five-year follow-up of Micropolyspora faeni antibody in smoking and nonsmoking farmers.  

PubMed

To examine factors that influence changes in Micropolyspora faeni (MF) antibody titer in farmer's lung disease (FLD), we followed for 5 yr the prevalence of serum MF antibody and the epidemiologic factors (years on farm, hours in barn, and hay-handling time) among 92 dairy farmers in Hokkaido, Japan. The prevalence of MF antibody among nonsmokers was significantly higher than that among smokers: 27.1% versus 7.7% in 1979, 31.3% versus 2.9% in 1984. There was no remarkable change in overall prevalences of MF antibody between 1979 and 1984 (18.5 and 19.6%, respectively). However, out of 17 seropositive farmers, six (35%) became seronegative, and out of 75 seronegative farmers, seven (9.3%) became seropositive after 5 yr. The nonsmoking farmers who remained seronegative throughout the follow-up period were older and had worked longer on farms than the farmers with seroconversion. These results suggest that in addition to smoking habits, age and exposure time to MF influence the immune response to MF in dairy farmers. Out of 11 farmers who remained seropositive throughout the 5-yr period, two (18.2%) developed FLD. Therefore, continuously positive MF antibody is one of the risk factors in the development of FLD. PMID:2782740

Kusaka, H; Homma, Y; Ogasawara, H; Munakata, M; Tanimura, K; Ukita, H; Denzumi, N; Kawakami, Y

1989-09-01

188

Performance of short implants in partial restorations: 3-year follow-up of Osseotite implants.  

PubMed

Short-length implants should be at a performance disadvantage because of the more limited surface area with which to resist occlusal forces. Nevertheless, anecdotal observations find many short implants performing well in different restorative conditions. This retrospective, multicenter study seeks to compare formally implant performance based on length. The success of 7 and 8.5-mm Osseotite implants (Implant Innovations, Inc., Palm Beach Gardens, FL) was determined as: absence of mobility; no persistent and/or irreversible signs or symptoms of pain, infection, paresthesia, or violation of the mandibular canal; no evidence of peri-implant radiolucency; and no progressive crestal bone loss. Implant location, restoration type, bone density, and smoking status of the patients were recorded. A total of 188 patients received 311 short Osseotite implants that were placed mostly in soft bone and supported 216 partially edentulous cases in the maxilla or mandible. Most restorations (95.2%) are short-span fixed partial dentures placed in the posterior sextants. During 3 years of follow-up, 13 implants failed, yielding a cumulative success rate of 95.8%. In 9 of these cases, failure occurred before prosthetic loading, and in 4, the patient was a smoker. The overall success rate compares favorably with the available literature for the performance of implants in general, and short implants in particular. PMID:16160574

Goené, Ronnie; Bianchesi, Carlo; Hüerzeler, Markus; Del Lupo, Ricardo; Testori, Tiziano; Davarpanah, Mithriadade; Jalbout, Ziad

2005-09-01

189

Fifteen year follow-up study of VC and FEV1 in dust-exposed workers.  

PubMed

A baseline survey of 3457 male workers exposed to various forms of dust from 11 medical facilities throughout Japan was carried out in 1978 or 1979. We completed the present follow-up study 15 years later on 693 of the men. Vital capacity (VC) and forced expiratory volume in one second (FEV1) were analyzed as indices of lung function. We examined factors that affected both baseline and interval changes in VC and FEV1 by stepwise multiple regression analysis. In the cross-sectional data analysis of baseline, height, profusion rate (PR) and age were selected as predictor variables for VC and FEV1, additionally duration of working for FEV1. It indicated that baseline VC decreased by 84.0 ml with each increase in PR classification. Similarly, baseline FEV1 decreased by 146.6 ml with increasing PR. Baseline VC and FEV1 were both positively influenced by subject height. In the longitudinal analysis, baseline PR, age and smoking habits were selected for predictor variables for decline of VC and FEV1. It indicated a negative influence of baseline PR classification on VC and FEV1 changes (-5.0 and -7.5 ml/y, respectively). Smoking decreased VC and FEV1 by 6.1 and 5.8 ml/y, respectively. PMID:11341555

Taguchi, M; Aizawa, Y; Niitsuya, M; Sugiura, Y; Tonori, H; Tonori, Y

2001-04-01

190

276 A 4-Year Follow-up in Children With Moderate/Severe Asthma after Withdrawal 1 Year Omalizumab Treatment  

PubMed Central

Background Asthma guidelines include omalizumab in the step up management in those patients with severe non-controlled asthma despite the use of the inhaled corticosteroids (ICS) at the highest dose recommended and/or oral corticosteroids (OCS) courses. This communication describes the 4 year follow up of children with moderate/severe allergic asthma treated for 1 year with add-on omalizumab after discontinuation. Methods 7 children (6 to <12 years) with moderate/severe uncontrolled asthma following strict inclusion/exclusion criteria. The patients completed a 1 year treatment with omalizumab according to the DBPC CIGE025 clinical study protocol. Four years follow up after discontinuation of the study medication was performed. It included clinical assessment, different asthma-related outcomes and lung function in outpatient hospital office Results All patients that received xolair during the study period achieved good asthma control and high dose ICS (mean dose fluticasone 500 mcg) were could be discontinued. Surprisingly, the 7 patients that received Xolair for one year were completely free of asthma symptoms during the first 3 years of follow up. They did not use any additional asthma medication. After the third year of follow up, only 2 out of 7 (28%) patients begun with persistent asthma symptoms and exacerbations. These patients have required rescue medication and then regular controller medication (budesonide 400 mcg). We could not identified any risk factor helping in predicting those who had symptoms relapsing. Lung function, number of exacerbation, number of hospitalization, eosinophilia, IgE levels or previous treatments with OCS Conclusions Most of these patients 5 out of 7 still remain asymptomatic 4 years after discontinuation Xolair without regular ICS treatment. They are still not using any controller medication only 2 patients had exacerbations and at present show persistent mild asthma controlled with medium ICS therapy. This follow up would generate the hypothesis that omalizumab could have a potential as a modifier of the natural history of asthma beyond the improvement of symptoms control in children with moderate/severe uncontrolled asthma. Further studies are needed to test this hypothesis.

Teijeiro, Alvaro; Badellino, H. A.; Gomez, R. Maximiliano; Canonica, Giorgio Walter; Baena-Cagnani, Carlos E.

2012-01-01

191

A 2-Year Prospective Follow-Up Study of the Course of Obsessive-Compulsive Disorder  

PubMed Central

Background Surprisingly little is known about the long-term course of obsessive-compulsive disorder (OCD). This prospective study presents 2-year course findings, as well as predictors of course, from the Brown Longitudinal Obsessive Compulsive Study, the first comprehensive prospective investigation of the observational course of OCD in a large clinical sample. Method The sample included 214 treatment-seeking adults with DSM-IV OCD at intake who identified OCD as the most problematic disorder over their lifetime. Subjects were enrolled from 2001–2004. At annual interviews, data on weekly OCD symptom status were obtained using the Longitudinal Interval Follow-Up Evaluation. Probabilities of full remission and partial remission over the first 2 years of collected data and potential predictors of remission were examined. Results The probability of full remission from OCD was 0.06, and the probability of partial remission was 0.24. Of the 48 subjects whose OCD symptoms partially or fully remitted, only 1 relapsed within the first 2 years. Earlier age at onset of OCD, greater severity of symptoms at intake, older age at intake, and being male were associated with a decreased likelihood of remission. Insight, diagnostic comorbidity, and treatment were not found to be associated with the likelihood of achieving full or partial remission. Conclusions Though one-quarter of the sample had periods of subclinical OCD symptoms during the prospective period, full remission was rare, consistent with the view of OCD as a chronic and persistent illness. Age at onset, OCD symptom severity, current age, and sex emerged as potent predictors of course.

Eisen, Jane L.; Pinto, Anthony; Mancebo, Maria C.; Dyck, Ingrid R.; Orlando, Maria E.; Rasmussen, Steven A.

2014-01-01

192

Lung function in adult idiopathic scoliosis: a 20 year follow up.  

PubMed Central

Severe idiopathic scoliosis may lead to respiratory failure, which can be treated by assisted ventilation. Twenty four patients with surgically untreated idiopathic scoliosis who had been examined in 1968 were re-examined in 1988 to assess changes in lung function and risk factors for respiratory failure. The patients were aged 15-67 years in 1968 and had a scoliotic angle of 10-190 degrees and a vital capacity of 1.0-6.0 litres. Spirometric values and scoliotic angles were determined in 1968 and 1988, and arterial blood gas tensions in 1988. The decline in spirometric values over the 20 years was of the same magnitude as the predicted decline due to aging. Arterial blood gas tensions in 1988 were strongly correlated with the scoliotic angles and spirometric indices recorded in 1968. Hypoxaemia and hypercapnia was seen in four patients in 1988 (then aged 43-67 years) and these were the four patients who had a vital capacity below 43% predicted in 1968. The remaining 20 patients had blood gas values within normal limits. Two further patients had died from respiratory failure before 1988, so a total of six patients had developed respiratory failure. In a multiple logistic analysis vital capacity expressed as % predicted in 1968 was the strongest predictor of the development of respiratory failure, followed by the scoliotic angle. Respiratory failure occurred only in patients who had a vital capacity below 45% predicted in 1968 and an angle greater than 110 degrees. Thus respiratory failure develops in adults with scoliosis with a large angle and a low vital capacity when normal aging reduces the ventilatory capacity further. Such individuals merit close follow up.

Pehrsson, K; Bake, B; Larsson, S; Nachemson, A

1991-01-01

193

Exclusive Alternating Chemotherapy and Radiotherapy in Nonmetastatic Inflammatory Breast Cancer: 20 Years of Follow-Up  

SciTech Connect

Background: Locoregional treatment of inflammatory breast cancer (IBC) is crucial because local relapses may be highly symptomatic and are commonly associated with distant metastasis. With a median follow-up of 20 years, we report here the long-term results of a monocentric clinical trial combining primary chemotherapy (CT) with a schedule of anthracycline-based CT and an alternating split-course of radiotherapy (RT Asterisk-Operator CT) without mastectomy. Methods and Materials: From September 1983 to December 1989, 124 women with nonmetastatic IBC (T4d M0) were treated with three cycles of primary AVCMF chemotherapy (anthracycline, vincristine, cyclophosphamide, methotrexate, and 5-fluorouracil) and then an alternating RT Asterisk-Operator CT schedule followed by three cycles of FAC. Hormonal therapy was systematically administered: ovarian irradiation (12 Gy in four fractions) or tamoxifen 20 mg daily. Results: Local control was achieved in 82% of patients. The 10- and 20-year local relapse rates were 26% and 33%, respectively, but only 10% of locally controlled cases were not associated with concurrent distant metastasis. The 10- and 20-year overall survival rates were 39% and 19%, respectively. Severe fibrosis occurred in 54% of patients, grade 3 brachial plexus neuropathy in 4%, grade 2 pneumonitis in 9%. Grade 1, 2 and 3 cardiac toxicity was observed in 3.8%, 3.8% and 1.2% of cases respectively. Conclusions: This combined regimen allowed good long-term local control without surgery. Survival rates were similar to those obtained with conventional regimens (primary chemotherapy, total mastectomy, and adjuvant radiotherapy). Since IBC continues to be an entity with a dismal prognosis, this approach, safely combining preoperative or postoperative radiation therapy and systemic treatments, should be reassessed when suitable targeted agents are available.

Bourgier, Celine, E-mail: bourgier@igr.fr [Department of Radiation Oncology, Breast Unit, Institut Gustave Roussy, Villejuif (France); Pessoa, Eduardo Lima [Department of Radiation Oncology, Breast Unit, Institut Gustave Roussy, Villejuif (France); Dunant, Ariane [Biostatistics and Epidemiology Unit, Institut Gustave Roussy, Villejuif (France); Heymann, Steve [Department of Radiation Oncology, Breast Unit, Institut Gustave Roussy, Villejuif (France); Spielmann, Marc [Department of Medical Oncology, Institut Gustave Roussy, Villejuif (France); Uzan, Catherine [Department of Breast Surgery, Institut Gustave Roussy, Villejuif (France); Mathieu, Marie-Christine [Department of Pathology, Institut Gustave Roussy, Villejuif (France); Arriagada, Rodrigo [Department of Radiation Oncology, Breast Unit, Institut Gustave Roussy, Villejuif (France); Department of Radiation Oncology, Karolinska Institutet, Stockholm (Sweden); Marsiglia, Hugo [Department of Radiation Oncology, Breast Unit, Institut Gustave Roussy, Villejuif (France); Radiation Department University of Florence, Florence (Italy)

2012-02-01

194

Change in quality of life of medically hospitalized patients – A one-year follow-up study  

Microsoft Academic Search

Objectives: To examine changes in quality of life (QOL) among elderly medically hospitalized patients one year after hospitalization, and to explore factors associated with the changes.Methods: A one-year follow-up study included 363 (175 men) medical inpatients with age range 65–98 (mean 80.2, SD 7.5) years. Information was collected at baseline and follow-up using the WHOQOL-BREF questionnaire assessing the physical, psychological,

Anne-Sofie Helvik; Knut Engedal; Geir Selbæk

2012-01-01

195

Wear rates of ceramic-on-ceramic bearing surfaces in total hip implants: A 12-year follow-up study  

Microsoft Academic Search

A retrospective clinical and radiographic analysis was performed on 58 patients (60 hips; mean age at time of surgery, 45.2 years) at a minimum of 10-year follow-up (mean, 12.7 years) after total hip replacement using a ceramic-on-ceramic bearing total hip implant (Autophor, Smith and Nephew, Memphis, TN). Mean wear rate at final follow-up was 0.21 mm, averaging 0.016 mm\\/y. There

Laith M. Jazrawi; Eric Bogner; Craig J. Della Valle; Frank S. Chen; Kevin I. Pak; Steven A. Stuchin; Victor H. Frankel; Paul E. Di Cesare

1999-01-01

196

Long term functioning in early onset psychosis: Two years prospective follow-up study  

PubMed Central

Background There were few studies on the outcome of schizophrenia in developing countries. Whether the outcome is similar to or different from developed world is still a point for research. The main aim of the current study was to know if patients with early onset non affective psychosis can behave and function properly after few years from start of the illness or not. Other aims included investigation of possible predictors and associated factors with remission and outcome. Method The study prospectively investigated a group of 56 patients with onset of psychosis during childhood or adolescence. Diagnosis made according to DSM-IV criteria and included; schizophrenia, psychotic disorder not otherwise specified and acute psychosis. Severity of psychosis was measured by PANSS. Measures of the outcome included; remission criteria of Andreasen et al 2005, the children's global assessment scale and educational level. Results Analysis of data was done for only 37 patients. Thirty patients diagnosed as schizophrenia and 7 with Psychotic disorder not otherwise specified. Mean duration of follow up was 38.4 +/- 16.9 months. At the end of the study, 6 patients (16.2%) had one episode, 23(62.1%) had multiple episodes and 8 (21.6%) continuous course. Nineteen patients (51.4%) achieved full remission, and only 11(29.7%) achieved their average educational level for their age. Twenty seven percent of the sample had good outcome and 24.3% had poor outcome. Factors associated with non remission and poor outcome included gradual onset, low IQ, poor premorbid adjustment, negative symptoms at onset of the illness and poor adherence to drugs. Moreover, there was tendency of negative symptoms at illness start to predict poor outcome. Conclusion Some patients with early onset non affective psychosis can behave and function properly after few years from the start of the illness. Although remission is a difficult target in childhood psychosis, it is still achievable.

2011-01-01

197

Adherence to Antiretroviral Therapy in Jinja, Uganda: A Six-Year Follow-Up Study  

PubMed Central

Introduction We report on the adherence experience of a group of people living with HIV on ART over six years in Uganda. Methods Between 2005 and 2009, we followed up 41 participants who were also part of a clinical trial comparing home and facility based delivery of ART in Jinja, eastern Uganda. We conducted qualitative in-depth interviews at enrolment, 3, 6, 18 and 30 months to capture experiences with adherence over time. In 2011 we returned to these participants to find out how they were fairing with long term adherence. We managed to retrace 24 participants and interviewed them about their experience. We thematically analysed the data and compared findings over time. Results Initially there were few barriers to adherence and many followed the adherence guidance closely. By year six, relaxation of these rules was noticeable although self-reported adherence continued to be high. Alcohol consumption was more common than before. Some relatives of the participants who had died claimed that some deaths were a result of alcohol. While participants reported that ART had allowed them to reclaim independence and return to work the changes in work and social routines created new challenges for adherence. Side effects like lipodystrophy were not only causing some stigma but for some tested their faith in the drugs. Many participants reported resumption of sexual lives but apart from those who selected same status partners, disclosure to new partners was minimal. Conclusion Good adherence practice to ART wanes over the long-term, and people who may have disclosed at initiation find it difficult to do so to new partners once they are healthy. Further adherence interventions and support with disclosure over the course of therapy may need to be considered. (Words: 283)

Mbonye, Martin; Seeley, Janet; Ssembajja, Fatuma; Birungi, Josephine; Jaffar, Shabbar

2013-01-01

198

Gait strategy in genetically obese patients: A 7-year follow up.  

PubMed

The aim of this study was to quantitatively evaluate the change in gait and body weight in the long term in patients with Prader-Willi Syndrome (PWS). Eight adults with PWS were evaluated at baseline and after 7 years. During this period patient participated an in- and out-patient rehabilitation programs including nutritional and adapted physical activity interventions. Two different control groups were included: the first group included 14 non-genetically obese patients (OCG: obese control group) and the second group included 10 age-matched healthy individuals (HCG: healthy control group). All groups were quantitatively assessed during walking with 3D-GA. The results at the 7-year follow-up revealed significant weight loss in the PWS group and spatial-temporal changes in gait parameters (velocity, step length and cadence). With regard to the hip joint, there were significant changes in terms of hip position, which is less flexed. Knee flexion-extension showed a reduction of flexion in swing phase and of its excursion. No changes of the ankle position were evident. As for ankle kinetics, we observed in the second session higher values for the peak of ankle power in terminal stance in comparison to the first session. No changes were found in terms of ankle kinetics. The findings demonstrated improvements associated to long-term weight loss, especially in terms of spatial-temporal parameters and at hip level. Our results back the call for early weight loss interventions during childhood, which would allow the development of motor patterns under normal body weight conditions. PMID:24763375

Cimolin, V; Vismara, L; Galli, M; Grugni, G; Cau, N; Capodaglio, P

2014-07-01

199

Supported local implementation of clinical guidelines in psychiatry: a two-year follow-up  

PubMed Central

Background The gap between evidence-based guidelines for clinical care and their use in medical settings is well recognized and widespread. Only a few implementation studies of psychiatric guidelines have been carried out, and there is a lack of studies on their long-term effects. The aim of this study was to measure compliance to clinical guidelines for treatment of patients with depression and patients with suicidal behaviours, two years after an actively supported implementation. Methods Six psychiatric clinics in Stockholm, Sweden, participated in an implementation of the guidelines. The guidelines were actively implemented at four of them, and the other two only received the guidelines and served as controls. The implementation activities included local implementation teams, seminars, regular feedback, and academic outreach visits. Compliance to guidelines was measured using quality indicators derived from the guidelines. At baseline, measurements of quality indicators, part of the guidelines, were abstracted from medical records in order to analyze the gap between clinical guidelines and current practice. On the basis of this, a series of seminars was conducted to introduce the guidelines according to local needs. Local multidisciplinary teams were established to monitor the process. Data collection took place after 6, 12, and 24 months and a total of 2,165 patient records were included in the study. Results The documentation of the quality indicators improved from baseline in the four clinics with an active implementation, whereas there were no changes, or a decline, in the two control clinics. The increase was recorded at six months, and persisted over 12 and 24 months. Conclusions Compliance to the guidelines increased after active implementation and was sustained over the two-year follow-up. These results indicate that active local implementation of clinical guidelines involving clinicians can change behaviour and maintain compliance.

2010-01-01

200

Follow-Up 89. Minnesota High School Follow-Up. Class of 1988: One Year Later. Trend Data: 1978-1988.  

ERIC Educational Resources Information Center

A study examined the educational and employment activities of members of Minnesota's high school class of 1988. Data regarding 15,232 students (14,151 graduates, 503 dropouts, and 578 students school leavers not classified as dropouts) were collected from 87 high schools participating in the Minnesota Secondary School Follow-up System and from 966…

Sedey, John M.

201

Japanese encephalitis (JE) part II: 14 years' follow-up of survivors.  

PubMed

Japanese encephalitis, the commonest Arbovirus encephalitis, has been endemic in many parts of Asia, the Pacific Islands, and India; also, there have been many epidemics. Most of the post JE cases have been associated with neurological and neuropsychiatric deficits but have not been properly classified and followed. Practically all the previous studies were in children or young adults. The aim of this study, involving only adult cases, the largest ever being reported, has been to follow the 688/1,199 survivors of JE patients out of 1,282 of acute cases admitted during four epidemics for a period of 14 years after properly classifying the sequelae. This prospective study was conducted in B.R.D. Medical College Gorakhpur (India), involving 665/688 post JE cases with neuropsychiatric deficits from four epidemics of 1978, 1980, 1988 and 1989 which were properly classified in nine groups. While the first epidemic of 1978 was being studied, more disastrous episodes flared up and the patients were subsequently added. Hence, the total duration of this prospective study was from November 1978 to December 2003. There were 14 defaulted initially from 688 followed (23/688 without sequelae and 665/688 with neuropsychiatric deficits), and later 130 were lost from time to time at various stages of follow up. Four out of 23/688 discharged without any deficit had to be readmitted for bizarre movements, assaultative behaviour and euphoria without fever and altered sensorium. All of them improved by symptomatic treatment. Progressive improvement occurred in all the parameters consisting of psychological disturbances, higher cerebral dysfunction, speech disorders (dysphonia, dysarthria, dysphasias, apraxia and agnosia), extra pyramidal, pyramidal features, and hypothalamic disturbances, cranial nerves including pupils and fundi and seizures. Maximum cases improved between 6 months (55%) to 1 year (78%). Only some features improved between 5 to 14 years. Four patients of hemiplegia remained bed ridden. Some non disabling features like dysarthria and corticospinal features without paralysis persisted in 5% (95% improved) and 74% (26% improved) respectively. One patient with bizarre movement and nine with marked tremors could not regain normalcy. A large number of patients of JE are left with several minor or gross residual neuropsychiatric and neurological features after the acute phase. In this series also the discharged patients with neurological deficits who were quite disabled initially and needed constant care by family members and also those who required some help intermittently improved with passage of time and eventually returned to normal life. Some of them were left with non-disabling residual neurological signs even after 14 years. Fourteen of 544 (3%) could not return to their livelihood. PMID:21681633

Sarkari, N B S; Thacker, A K; Barthwal, S P; Mishra, V K; Prapann, Shiv; Srivastava, Deepak; Sarkari, M

2012-01-01

202

Serum Adiponectin and Type 2 Diabetes: A 6-Year Follow-Up Cohort Study  

PubMed Central

Background Studies on factors which may predict the risk of diabetes are scarce. This prospective cohort study was conducted to determine the association between adiponectin and type 2 diabetes among Korean men and women. Methods A total of 42,845 participants who visited one of seven health examination centers located in Seoul and Gyeonggi province, Republic of Korea between 2004 and 2008 were included in this study. The incidence rates of diabetes were determined through December 2011. To evaluate the effects of adiponectin on type 2 diabetes, the Cox proportional hazard model was used. Results Of the 40,005 participants, 959 developed type 2 diabetes during a 6-year follow-up. After the adjustment for age, body mass index (BMI), and waist circumference, the risks for type 2 diabetes in participants with normoglycemia had a 1.70-fold (95% confidence interval [CI], 1.21 to 2.38) increase in men and a 1.83-fold (95% CI, 1.17 to 2.86) increase in women with the lowest tertile of adiponectin when compared to the highest tertile of adiponectin. For participants with impaired fasting glucose (IFG), the risk for type 2 diabetes had a 1.46-fold (95% CI, 1.17 to 1.83) increase in men and a 2.52-fold (95% CI, 1.57 to 4.06) increase in women with the lowest tertile of adiponectin. Except for female participants with normoglycemia, all the risks remained significant after the adjustment for fasting glucose and other confounding variables. Surprisingly, BMI and waist circumference were not predictors of type 2 diabetes in men or women with IFG after adjustment for fasting glucose and other confounders. Conclusion A strong association between adiponectin and diabetes was observed. The use of adiponectin as a predictor of type 2 diabetes is considered to be useful.

Ahn, Chul Woo; Park, Jong Suk; Park, Chang Gyu; Kim, Hyon-Suk; Lee, Sang-Hak; Park, Sungha; Lee, Myoungsook; Lee, Chang Beom; Park, Hye Soon; Kimm, Heejin; Choi, Sung Hee; Sung, Jidong; Oh, Seungjoon; Joung, Hyojee; Kim, Sung Rae; Youn, Ho-Joong; Kim, Sun Mi; Lee, Hong Soo; Mok, Yejin; Choi, Eunmi; Yun, Young Duk; Baek, Soo-Jin; Jo, Jaeseong; Huh, Kap Bum

2013-01-01

203

Relocation of ventricular catheter trough ventriculostomy due to congenital unilateral hydrocephalus: Nine year follow-up  

PubMed Central

Background: Congenital unilateral hydrocephalus is an uncommon entity occurring almost exclusively in children. Atresia, stenosis, membranous occlusion and even functional obstruction of the foramen of Monro have been described to be the main cause of this type of hydrocephalus. There are two options available in the surgical management of unilateral hydrocephalus: one is the placement of shunt CSF diversion from the dilated ventricle and the other is fenestration of the occluded foramen of Monro or septum pellucidum by endoscopy or by stereotactic method. Migration of the ventriculoperitoneal (VP) shunt in or out of ventricles is not so uncommon, but the relocation of the ventricular tip of a catheter from the ventricle into the quadrigeminal cisterns and superior vermis in association with ventriculostomy is extremely rare. Spontaneous ventriculostomy is a rare event and results from spontaneous rupture of a ventricle into the subarachnoid space. Case Description: A 5½-month-old baby with a right-sided congenital unilateral hydrocephalus underwent a VP shunt andhad experienced an uneventful outcome. Four years later on an MR imaging examination, the tip of the ventricular catheter passing through the medial wall of the ventricle and the quadrigeminal cistern was found to be situated in the superior vermis. During the follow-up period, there were no neurological difficulties. The cognitive and motor skill development corresponded well with the child's age. It transpired that the hydrocephalic ventricle reduced its size dramatically to normal. Conclusion: We have described the extremely rare site of the relocation of the ventricular catheter after the treatment of the congenital unilateral hydrocephalus by VP shunting. Spontaneous ventriculostomy as a rare phenomenon may be the explanation of the relocation of the ventricular catheter.

Zoran, Milenkovic J.; Biljana, Stevanovic S.; Ivana, Markovic P.

2011-01-01

204

Follow-up study after more than one year including 100 patients treated for superficial mycoses.  

PubMed

A total of 100 patients with dermatomycoses were treated with econazole nitrate 1% or with the same compound combined with triamcinolone acetonide 0.1%. The patients were supposed to undergo clinical and mycological follow-up examinations at an average of 15 months after cure had been obtained. Of the 100 patients, 83 were followed up: 78 (95%) reported neither relapses nor reinfections; 4 (5%) presented with clinical symptoms and positive mycological examination and in 1 patient the mycological examination was positive but no clinical symptoms were present. Generally speaking, the results can be considered excellent. PMID:7351270

Grigoriu, D; Pallarés, J L

1980-01-01

205

Parent-identified problem preschoolers: Mother-child interaction during play at intake and 1-year follow-up  

Microsoft Academic Search

Parent-referred 2- and 3-year-olds and controls, participating in a longitudinal study of hyperactivity and related behavior problems, were observed with their mothers during play at an initial assessment and a 1-year follow-up. Mothers of problem children provided more redirection initially and made more negative control statements at follow-up than mothers of controls; problem youngsters tended to play more aggressively. Sex

Susan B. Campbell; Anna Marie Breaux; Linda J. Ewing; Emily K. Szumowski; Elizabeth W. Pierce

1986-01-01

206

Employment grade differences in cause specific mortality. A 25 year follow up of civil servants from the first Whitehall study  

Microsoft Academic Search

STUDY OBJECTIVETo test the hypothesis that the association between socioeconomic status and mortality rates cuts across the major causes of death for middle aged and elderly men.DESIGN25 year follow up of mortality in relation to employment grade.SETTINGThe first Whitehall study.PARTICIPANTS18 001 male civil servants aged 40–69 years who attended the initial screening between 1967 and 1970 and were followed up

Caroline T M van Rossum; Martin J Shipley; Hendrike van de Mheen; Diederick E Grobbee; Michael G Marmot

2000-01-01

207

Convergence of Self-Report and Archival Crash Involvement Data: A Two-Year Longitudinal Follow-Up  

Microsoft Academic Search

This study constructively extends Arthur et al. (2001) by assessing the convergence of self-report and archival motor vehicle crash involvement and moving violations data in a 2-year longitudinal follow-up. The relationships among these criteria, conscientiousness, and driving speed were also assessed using both predictive and postdictive criterion-related validation designs. Data were collected from a 2-year follow-up sample of 334 participants.

Winfred Arthur; Suzanne T. Bell; Bryan D. Edwards; Eric Anthony Day; Travis C. Tubre; Amber H. Tubre

2005-01-01

208

Sociodemographic and Psychopathological Risk Factors for Repetition of Attempted Suicide: A 5Year Follow-Up Study  

Microsoft Academic Search

The present study examines the association between repetition of suicide attempts and sociodemographic and psychopathological characteristics of patients during a 5-year follow-up period. Participants were 874 suicide attempters referred to the University Hospital of Ghent, among whom 361 (41.3%) patients were available for follow-up analysis. Within 5 years, 29.2% of those admitted for an index suicide attempt repeated non-fatal suicidal

Gerrit Scoliers; Gwendolyn Portzky; Kees van Heeringen; Kurt Audenaert

2009-01-01

209

Mortality attributable to cigarette smoking in Taiwan: a 12-year follow-up study  

PubMed Central

BACKGROUND—Assessment of the impact of cigarette smoking on mortality helps to indicate the importance of tobacco control in a given country.?OBJECTIVES—To examine the relative risk of dying from various diseases for cigarette smoking and to estimate annual mortality attributable to cigarette smoking in Taiwan.?DESIGN—Prospective cohort study.?SUBJECTS AND SETTING—A cohort of 14 397 male and female residents aged 40 years or older recruited from 12 townships and precincts in Taiwan from 1982 to 1986. Information on cigarette smoking was collected from each subject at local health centres through a standardised personal interview based on a structured questionnaire. They were followed up regularly to determine their vital status until 1994.?MAIN OUTCOME MEASURES—Cox's proportional hazards regression models were used to derive relative risks of cause-specific mortality for current cigarette smokers compared with never-smokers, and to examine dose-response relationships between mortality from various causes and several measures of cigarette smoking (daily consumption, duration, age of initiation, and cumulative smoking in pack-years).?RESULTS—A total of 2552 persons died during the study period. Among men, cigarette smoking was significantly associated with an increased risk of dying from all causes combined (relative risk (RR) = 1.3); cancer of all sites combined (RR = 1.5); cancers of the stomach (RR = 1.9), liver (RR = 2.2), and lung (RR = 3.7); ischaemic heart disease (RR = 1.8); other heart diseases (RR = 1.4); and chronic obstructive pulmonary disease (RR = 1.9). Among women, cigarette smoking was significantly associated with an increased risk of dying from all causes combined (RR = 1.8), cancer of the lung (RR = 3.6), and peptic ulcer (RR = 17.8). The estimated number of deaths attributable to cigarette smoking in Taiwan in 1994 was 8161 (13.9% of total deaths) for men and 1216 (3.3% of total deaths) for women. In the same year cigarette smoking caused 21.3% and 2.9% of cancer deaths in men and women, respectively, in Taiwan.?CONCLUSIONS—Cigarette smoking has a striking impact on overall mortality and deaths from various causes in the Taiwanese population. Tobacco control should be established as the top priority in public health programmes in Taiwan.???Keywords: mortality; smoking-attributable diseases; Taiwan

Liaw, K.; Chen, C.

1998-01-01

210

Ewing sarcoma of the first metacarpal with a 9-year follow-up: case report.  

PubMed

Ewing sarcoma is a primary bone tumor that rarely occurs in the hand. We present a case involving the thumb metacarpal with long-term follow-up. Carpometacarpal and metacarpophalangeal arthrodeses with autograft are relatively simple procedures that stabilized the thumb and preserved satisfactory function. PMID:23809471

Ramos-Pascua, Luis R; Fernández-Hernández, Oscar; Sánchez Herráez, Sergio; Santos Sánchez, José Ángel; Flores Corral, Teresa

2013-08-01

211

Effects of Stimulant Medication on Growth Rates across 3 Years in the MTA Follow-up  

ERIC Educational Resources Information Center

Objective: To evaluate the hypothesis of stimulant medication effect on physical growth in the follow-up phase of the Multimodal Treatment Study of Children With ADHD. Method: Naturalistic subgroups were established based on patterns of treatment with stimulant medication at baseline, 14-, 24-, and 36-month assessments: not medicated (n = 65),…

Swanson, James M.; Elliott, Glen R.; Greenhill, Laurence L.; Wigal, Timothy; Arnold, L. Eugene; Vitiello, Benedetto; Hechtman, Lily; Epstein, Jeffery N.; Pelham, William E.; Abikoff, Howard B.; Newcorn, Jeffrey H.; Molina, Brooke S. G.; Hinshaw, Stephen P.; Wells, Karen C.; Hoza, Betsy; Jensen, Peter S.; Gibbons, Robert D.; Hur, Kwan; Stehli, Annamarie; Davies, Mark; March, John S.; Conners, C. Keith; Caron, Mark; Volkow, Nora D.

2007-01-01

212

Meniscal allograft transplantation: A 1- to 5-year follow-up of 22 patients  

Microsoft Academic Search

Between October 1991 and December 1995, a total of 22 patients (23 knees) underwent meniscal transplantation with nonirradiated, cryopreserved allografts. Implantation was arthroscopically assisted using bone plugs to prevent meniscal extrusion and maintain weight-bearing functional position. Patients were evaluated with an average follow-up of 40 months (range, 13 to 69 months) using the International Knee Documentation Committee, Lysholm, and Tegner

George T. Stollsteimer; Walter R. Shelton; Andrea Dukes; Anna Laura Bomboy

2000-01-01

213

Follow-up of invasive pituitary macroadenoma in 56 patients within a duration of 5 years.  

PubMed

From June 1986 to September 1996, 56(30%) patients with invasive pituitary macroadenoma were studied retrospectively. We compared the clinical and endocrinological characteristics, neuroimaging findings, and surgical outcome of these patients in a period of follow up of 5 years. Twenty-one patients (38%) were found to have a prolactinoma, 8 patients (14%) had a GH-producing adenoma, and 27 patients (48%) had non-functional tumors. Pituitary apoplexy was found in 16 cases (29%). Their age ranged from 15 to 72 years and no sex difference (F:M = 27:29) was found. According to Hardy's classification, all the 56 tumors were invasive pituitary macroadenoma, of a tumor size more than 10 mm with sellar floor erosion partially or diffusely or paracarvenous sinus invasion. Those tumors were divided into grade III (tumor causing localized perforation of the sellar floor), and IV (tumor destroying entire sellar floor diffusely); the tumors were further subdivided into stage C (3rd ventricle grossly displaced), D (intracranial intradural extension) and E (tumors invading the cavernous sinus through the lateral dural envelope of the sellar). Eight out of 56 tumors belonged to grade III stage C, 18 tumors were grade III stage D, 8 tumors were grade IV stage D, and the other 22 were grade IV stage E. Fifty-one patients received transsphenoidal craniectomy for tumor removal, one patient took subfrontal craniotomy only and 4 cases received both. Most patients improved significantly in visual field and general quality of life after surgery. In this study, it was concluded that: 1) surgical intervention as quick as possible was proven advantageous, especially in patients with an invasive macroadenoma; 2) in cases with invasive pituitary macroadenomas, the patients, with grade III and IV tumors, had a longer symptom-free interval than those who refused surgical intervention and radiotherapy with the same grade tumor; 3) to achieve satisfactory late results, multidisciplinary treatment was necessary: post-operative radiotherapy ranging from 4500 to 6500 rads was done in 50 patients, endocrine therapy in 52 patients and adjunct bromocriptine treatment was done in 13 patients with prolactinomas; 4) symptomatic recurrence or elevated postoperative hormone levels occurred in 20(35%) cases. There was a high incidence of recurrence in 6(6/20) GH-secreting tumors, and in 8(8/20) prolactinomas with preoperative prolactin levels more than 200 eta g/dl. PMID:11079292

Chang, C Z; Huang, Y H; Howng, S L

2000-07-01

214

Preclinical atherosclerosis and metabolic syndrome increase cardio- and cerebrovascular events rate: a 20-year follow up  

PubMed Central

Background Intima-media thickness (IMT) is a validated marker of preclinical atherosclerosis and a predictor of cardiovascular events. Patients We studied a population of 529 asymptomatic patients (age 62?±?12.8 years), divided into two groups of subjects with and without Metabolic Syndrome (MetS). Methods All patients, at baseline, have had a carotid ultrasound evaluation and classified in two subgroups: the first one without atherosclerotic lesions and the second one with preclinical atherosclerosis (increased IMT or asymptomatic carotid plaque). Cardiovascular endpoints were investigated in a 20-years follow-up. Results There were 242 cardiovascular events: 144 among patients with MetS and 98 among in healthy controls (57.4% vs. 35.2%; P?

2013-01-01

215

Slater revisited: 6 year follow up study of patients with medically unexplained motor symptoms  

PubMed Central

Objective: To investigate psychiatric and neurological morbidity, diagnostic stability, and indicators of prognosis in patients previously identified as having medically unexplained motor symptoms. Design: Follow up study. Setting: National Hospital for Neurology and Neurosurgery, London—a secondary and tertiary referral hospital for neurological disorders. Subjects: 73 patients with medically unexplained motor symptoms admitted consecutively in 1989-91. 35 (48%) patients had absence of motor function (for example, hemiplegia) and 38 (52%) had abnormal motor activity (for example, tremor, dystonia, or ataxia). Main outcome measures: Neurological clinical diagnosis at face to face reassessment by a neurologist and a psychiatric diagnosis after a standardised assessment interview—the schedule for affective disorders and schizophrenia—conducted by a psychiatrist. Results: Good follow up data were available for 64 subjects (88%). Only three subjects had new organic neurological disorders at follow up that fully or partly explained their previous symptoms. 44/59 (75%) subjects had had psychiatric disorders; in 33 (75%) patients, the psychiatric diagnosis coincided with their unexplained motor symptoms. 31/59 (45%) patients had a personality disorder. Three subjects had developed new psychiatric illnesses at follow up, but in only one did the diagnosis account for the previous motor symptoms. Resolution of physical symptoms was associated with short length of symptoms, comorbid psychiatric disorder, and a change in marital status during follow up. Conclusions: Unlike Slater’s study of 1965, a low incidence of physical or psychiatric diagnoses which explained these patients’ symptoms or disability was found. However, a high level of psychiatric comorbidity existed. Key messages Motor symptoms that remain unexplained medically despite thorough investigation are a common clinical problem, but the emergence of a subsequent organic explanation for these symptoms is rare The prevalence of coexistent affective and anxiety disorders is high and many patients also have a personality disorder Patients with a shorter duration of symptoms and coexistent anxiety or depression are likely to do better at follow up Reinvestigation of these patients is both expensive and potentially dangerous and should be avoided where no clear clinical indication exists

Crimlisk, Helen L; Bhatia, Kailash; Cope, Helen; David, Anthony; Marsden, C David; Ron, Maria A

1998-01-01

216

Risk Factors for End-Stage Renal Disease: 25-Year Follow-up  

PubMed Central

Background Few cohort studies have focused on risk factors for end-stage renal disease (ESRD). This investigation evaluated the prognostic value of several potential novel risk factors for ESRD after considering established risk factors. Methods We studied 177 570 individuals from a large integrated health care delivery system in northern California who volunteered for health checkups between June 1, 1964, and August 31, 1973. Initiation of ESRD treatment was ascertained using US Renal Data System registry data through December 31, 2000. Results A total of 842 cases of ESRD were observed during 5 275 957 person-years of follow-up. This comprehensive evaluation confirmed the importance of established risk factors, including the following: male sex, older age, proteinuria, diabetes mellitus, lower educational attainment, and African American race, as well as higher blood pressure, body mass index, and serum creatinine level. The 2 most potent risk factors were proteinuria and excess weight. For proteinuria, the adjusted hazard ratios (HRs) were 7.90 (95% confidence interval [CI], 5.35–11.67) for 3 to 4+ on urine dipstick, 3.59 (2.82–4.57) for 1 to 2+ on urine dipstick, and 2.37 (1.79–3.14) for trace vs negative on urine dipstick. For excess weight, the HRs were 4.39 (95% CI, 3.38–5.70) for class 2 to class 3 obesity, 3.11 (2.51–3.84) for class 1 obesity, and 1.65 (1.39–1.97) for overweight vs normal weight. Furthermore, several independent novel risk factors for ESRD were identified, including lower hemoglobin level (1.33 [1.08–1.63] for lowest vs highest quartile), higher serum uric acid level (2.14 [1.65–2.77] for highest vs lowest quartile), self-reported history of nocturia (1.36 [1.17–1.58]), and family history of kidney disease (HR, 1.40 [95% CI, 1.02–1.90]). Conclusions We confirmed the importance of established ESRD risk factors in this large cohort with broad sex and racial/ethnic representation. Lower hemoglobin level, higher serum uric acid level, self-reported history of nocturia, and family history of kidney disease are independent risk factors for ESRD.

Hsu, Chi-yuan; Iribarren, Carlos; McCulloch, Charles E.; Darbinian, Jeanne; Go, Alan S.

2009-01-01

217

Treatment of vulvar intraepithelial neoplasia with topical imiquimod: Seven years median follow-up of a randomized clinical trial  

Microsoft Academic Search

ObjectiveRecently we reported on the efficacy of imiquimod for treating vulvar intraepithelial neoplasia (VIN) in a placebo-controlled, double-blinded randomized clinical trial (RCT). Four weeks after treatment, a complete response was observed in 35% of patients and a partial response in 46%. All complete responders remained disease-free at 12months follow-up. In the current investigations, we assessed long-term follow-up at least 5years

Annelinde Terlou; Manon van Seters; Patricia C. Ewing; Neil K. Aaronson; Chad M. Gundy; Claudia Heijmans-Antonissen; Wim G. V. Quint; Leen J. Blok; Marc van Beurden; Theo J. M. Helmerhorst

2011-01-01

218

Healing after horizontal root fractures: 3 cases with 2-year follow-up.  

PubMed

Among dental traumas, horizontal root fractures are relatively uncommon injuries. Proper initial management and periodical evaluation is essential for the successful treatment of a root-fractured tooth. If pulpal necrosis develops, endodontic treatment is indicated, exclusively for the coronal fragment. Fragment diastases exert a great influence on healing at the fracture line and on pulpal necrosis. An adequately treated root-fractured tooth has a good prognosis. This case report describes the treatment and 2-yr follow up of 3 maxillary central incisors, first with horizontal root fracture, second with horizontal root fracture and avulsion, and third with horizontal root fracture and lateral luxation. All three cases were treated with mineral trioxide aggregate (ProRoot, Dentsply). During 2 yr of follow-up evaluation, the root-fractured teeth of the present patients were well retained in the arch, showing periodontal healing, even after endodontic treatment. PMID:24790926

Choi, Yoorina; Hong, Sung-Ok; Lee, Seok-Ryun; Min, Kyung-San; Park, Su-Jung

2014-05-01

219

Interferon treatment of uterine cervical carcinoma: 20 years of follow-up.  

PubMed

Twenty-seven randomized patients with biopsy proven carcinoma of the uterine cervix were treated with human natural leucocytic interferon (HNLI) and followed up, while 30 randomized patients were followed up in the control group and were not treated with HNLI. International Federation of Gynecology and Obstetrics (FIGO) classification of HNLI-treated patients was IA: 8, IB: 9, IIA and IIB: 10. FIGO classification of control non-treated patients was IA: 9, IB: 10, IIA and IIB: 12. HNLI was applied locally at 2x10(6) U daily in pessaries for 21 days before surgery. Survival analysis of the HNLI-treated patients after 240 months of observation showed that 20 patients (74.07%) out of 27 survived, and in the control group 14 patients (46.67%) out of 30 survived. Statistical difference between the HNLI-treated group and control group of patients is significant P<0.05. PMID:10940515

Iki?, D; Krusi?, J; Ivankovi?, D

2000-09-29

220

Healing after horizontal root fractures: 3 cases with 2-year follow-up  

PubMed Central

Among dental traumas, horizontal root fractures are relatively uncommon injuries. Proper initial management and periodical evaluation is essential for the successful treatment of a root-fractured tooth. If pulpal necrosis develops, endodontic treatment is indicated, exclusively for the coronal fragment. Fragment diastases exert a great influence on healing at the fracture line and on pulpal necrosis. An adequately treated root-fractured tooth has a good prognosis. This case report describes the treatment and 2-yr follow up of 3 maxillary central incisors, first with horizontal root fracture, second with horizontal root fracture and avulsion, and third with horizontal root fracture and lateral luxation. All three cases were treated with mineral trioxide aggregate (ProRoot, Dentsply). During 2 yr of follow-up evaluation, the root-fractured teeth of the present patients were well retained in the arch, showing periodontal healing, even after endodontic treatment.

Choi, Yoorina; Hong, Sung-Ok; Lee, Seok-Ryun; Min, Kyung-San

2014-01-01

221

Laparoscopic sacrocolpopexy: results of a 100-patient series with 8 years follow-up  

Microsoft Academic Search

ObjectiveAssess the feasibility, safety and results at mean term of laparoscopic promontofixation, and to describe the operative technique.DesignRetrospective study.SettingDepartment of Gynaecology, Obstetrics and Reproductive Medicine, Caen University Hospital, France.SampleOne hundred patients included from June 1993 to June 2001.MethodsPre- and post-operative clinical assessment of pelvic statics problems in accordance with the international POP-Q classification. Annual follow-up of patients and recording of

Peter von Theobald; Angélique Chéret

2004-01-01

222

Carpentier-Edwards pericardial valves in the mitral position: Ten-year follow-up  

Microsoft Academic Search

Objective: The first generation of pericardial valves was withdrawn from the market because of a high rate of premature failure. With an original design, Carpentier-Edwards pericardial valves promised improved results.Methods: One hundred fifty patients who underwent isolated mitral valve replacement, between July 1984 and December 1993, with Carpentier-Edwards pericardial bioprostheses in our institution were followed up. Patient mean age was

M. R. Aupart; P. H. Neville; S. Hammami; A. L. Sirinelli; Y. A. Meurisse; M. A. Marchand

1997-01-01

223

Vagus nerve stimulation in patients with catastrophic childhood epilepsy, a 2-year follow-up study  

Microsoft Academic Search

Purpose: To establish the long-term efficacy and tolerability of vagus nerve stimulation (VNS) in children with a Lennox-like syndrome. Method: This study was a longitudinal observational prospective cohort analysis. Baseline: 6 months. Follow-up: 24 months. Screening (baseline and every 6 months): MRI (baseline only), EEG, neuropsychological evaluation, ECG and blood sampling for antiepileptic drug levels. Nineteen children are included. Results:

H. J. M. Majoie; M. W. Berfelo; A. P. Aldenkamp; W. O. Renier; A. G. H. Kessels

2005-01-01

224

Ten to 14Year Follow-up of the Nirschl Surgical Technique for Lateral Epicondylitis  

Microsoft Academic Search

Background: Good to excellent short-term results have been reported for the surgical treatment of lateral epicondylitis using various surgical techniques.Hypothesis: Surgical treatment for lateral epicondylitis using the mini-open Nirschl surgical technique will lead to durable results at long-term follow-up.Study Design: Case series; Level of evidence, 4.Methods: Records from 139 consecutive surgical procedures (130 patients) for lateral epicondylitis performed by 1

Jonathan H. Dunn; John J. Kim; Lonnie Davis; Robert P. Nirschl

2008-01-01

225

Arthroscopic collagen meniscus implant results at 6 to 8 years follow up  

Microsoft Academic Search

Meniscal substitution is a fundamental procedure to prevent osteoarthritis of the knee after massive meniscectomy. Stone,\\u000a Steadman and Rodkey have developed a bioreadsorbable collagen matrix (CMI) which acts as a scaffold to restore the original\\u000a medial meniscal. The objective of this study was to prospectively evaluate the results of CMI implantation at a follow up\\u000a from a minimum of 6

Stefano Zaffagnini; Giovanni Giordano; Alberto Vascellari; Danilo Bruni; Maria Pia Neri; Francesco Iacono; Elizaveta Kon; Mirco Lo Presti; Maurilio Marcacci

2007-01-01

226

Heroin addicts and methadone treatment in Albuquerque: a 22-year follow-up  

Microsoft Academic Search

All heroin addicts who registered for methadone treatment in Albuquerque in 1969–1971, 1019 in all, were the subjects of this follow-up study, conducted in 1991–1993. The cohort was almost entirely of Hispanic (Chicano) ethnicity, 86% male, with median age 27 at entry. We located 776, dead or alive, and we were able to interview 243 concerning many aspects of their

Avram Goldstein; James Herrera

1995-01-01

227

Symptomatic improvement in uterine myomas after MRgFUS: 4 year follow up  

NASA Astrophysics Data System (ADS)

Objective: To assess the long-term improvement in symptoms after magnetic resonance-guided focused ultrasound surgery (MRgFUS) for uterine myomas. Methods: Japanese women with symptomatic myomas underwent MRgFUS using the ExAblate 2000 system. The symptom severity score (SSS) was examined before and after the treatment at 3, 6, 12, 24, and 48 months. Simultaneously, we asked the patients' satisfaction level regarding the overall change of subjective symptoms: symptom free, improved a great deal, improved to some extent, no change, or worsened. The myoma volumes were measured at 6, 12, 24, 36 and 48 months after MRgFUS. Results: No severe adverse event occurred with any of the patients. The mean SSS value before treatment was 38.3+/-21.5 (n = 106), which diminished significantly during follow-up for 3-48 months after treatment. Patients' satisfaction level was favorable, although the response rate was low. Over 80% of the patients replied that their symptoms were improved to at least some extent, and over 50% of the patients replied that their symptoms were improved a great deal. This trend continued throughout this follow up period. The mean myoma volume was also decreased from the pretreatment volume in this follow up period. Conclusion: MRgFUS is an effective and safe method for treating symptomatic uterine myomas. Long-term symptomatic improvement is promising.

Funaki, Kaoru

2011-09-01

228

Out-of-hospital follow-up after low risk breast cancer within a care network: 14-year results.  

PubMed

The delegation of low-risk breast cancer patients' follow-up to non-hospital practitionners (NHP), including gynaecologists and general practitioners, has been assessed prospectively within a care network in the Paris region. Patients with early stage breast cancer were eligible. The follow-up protocol was built according to international guidelines. By 2012, 289 NHPs were following 2266 patients treated in 11 centres. Median follow-up time was 7.4 years. The mean intervals between two consecutive consultations were 9.5 [9.2-9.8] months for women supposed to be monitored every 6 months and 12.5 [12.2-12.8] for those requiring annual monitoring. The relapse rate was 3.2% [2.1-4.3] at 5 years and 7.8% [5.9-9.7] at 10 years. Seventy one percent of relapses were diagnosed on a scheduled assessment. Only 6% were lost-to-follow-up. Delegating follow-up after low risk breast cancer to NHPs in a care network is feasible, well accepted and provides an alternative to follow-up in specialized centres. PMID:24656635

Houzard, Sophie; Dubot, Coraline; Fridmann, Sylvie; Dagousset, Isabelle; Rousset-Jablonski, Christine; Callet, Nasrine; Nos, Claude; Villet, Richard; Thoury, Anne; Delaloge, Suzette; Breuil Crockett, Flora; Fourquet, Alain

2014-08-01

229

Cementless acetabular fixation in patients 50 years and younger at 10 to 18 years of follow-up.  

PubMed

The purpose of the study was to evaluate the 10- to 18-year follow-up of cementless acetabular fixation in patients 50 years and younger. We retrospectively reviewed a consecutive group of 118 patients (144 hips) in whom primary total hip arthroplasty had been performed by 2 surgeons using a cementless acetabular component. Two (1.4%) cementless acetabular components were revised because of aseptic loosening. Twenty-four hips (16.7%) were revised for any mechanical failure of the acetabular component mostly related to acetabular liner wear and osteolysis. The average linear wear rate was 0.19 mm per year, which was higher than our previous reports with cemented acetabular fixation. The fiber mesh ingrowth surface of the cementless acetabular component in this study was superior to cemented acetabular components in terms of fixation. However, the high rates of wear and osteolysis have led to poor overall acetabular component construct survivorship. PMID:22266047

Teusink, Matthew J; Callaghan, John J; Warth, Lucian C; Goetz, Devon D; Pedersen, Douglas R; Johnston, Richard C

2012-08-01

230

A six year follow up study of the subclinical effects of carbon disulphide exposure on the cardiovascular system  

PubMed Central

Aims: A six year prospective cohort study was conducted to clarify whether the current carbon disulphide (CS2) exposure level is low enough to prevent subclinical health impairment and/or to ameliorate health effects due to previous high exposure. This paper describes the effects on the cardiovascular systems. Methods: The study subjects were 432 male workers exposed to CS2 and 402 non-exposed workers in Japan, all of whom were examined in 1992–93. A total of 251 CS2 exposed, 140 formerly exposed, and 359 non-exposed workers participated in the follow up survey (follow up rate 89.9%) in 1998–99. Mean duration of exposure was 19.3 years at the end the study. Mean CS2 and 2-thiothiazolidine-4-carboxylic acid (TTCA) concentrations were 5.0 ppm and 1.6 mg/g creatinine. Health items examined were serum biochemical indices including lipids and coagulation-fibrinolysis factors, blood pressure, aortic stiffness, ophthalmography, and electrocardiography at rest and after Master's double 2 step test. Potential confounding factors were adjusted for. Results: Incidence of ischaemic findings, defined as Minnesota codes I, IV1–3, V1–3 (at rest and after the load), or receiving treatment for ischaemia, was significantly higher in the exposed workers, especially for the spinning/refining workers (adjusted OR 2.1; 95% CI 1.1 to 4.0) or the highest quartile of six year mean TTCA (adjusted OR 3.9; 95% CI 1.8 to 8.7), although the observed increase in risk was diminished when rigorous ECG criteria were applied. Incidence of retinal microaneurysm was increased with marginal significance. Among cardiovascular risk factors we examined, only blood pressure values were significantly increased in the exposed workers. Conclusions: Increased risk of ischaemic electrocardiogram findings among Japanese viscose rayon workers was observed. Although its clinical significance is to be discussed, the current Japanese occupational exposure limit for CS2, 10 ppm, would be high to prevent subclinical cardiovascular effects in this study population.

Takebayashi, T; Nishiwaki, Y; Uemura, T; Nakashima, H; Nomiyama, T; Sakurai, H; Omae, K

2004-01-01

231

A Screening Instrument for Autism at 18 Months of Age: A 6Year Follow-up Study  

Microsoft Academic Search

ObjectivesA population of 16,235 children aged 18 months was screened using the Checklist for Autism in Toddlers (CHAT) to identify childhood autism (CA). Two further screening procedures were conducted at age 3 and 5 years. The population was followed up at age 7 years in order to establish the sensitivity, specificity, and positive predictive value of the instrument.

GILLIAN BAIRD; TONY CHARMAN; SIMON BARON-COHEN; ANTONY COX; JOHN SWETTENHAM; SALLY WHEELWRIGHT; AURIOL DREW

2000-01-01

232

Changes in lung function of granite crushers exposed to moderately high silica concentrations: a 12 year follow up  

Microsoft Academic Search

45 granite crushers and 45 age and smoking matched referents underwent pulmonary function tests in 1976 and 1988. On average, the granite crushers at follow up had worked for 22 years, were 52 (range 36-78) years old, and had inhaled a cumulated amount of 7 mg of silica in the respirable dust fraction. Between 1976 and 1988 the average concentration

P Malmberg; H Hedenström; B M Sundblad

1993-01-01

233

A Follow-Up Study of One Group of Achievers and Underachievers Four Years after High School Graduation.  

ERIC Educational Resources Information Center

A four-year follow-up study comparing 73 gifted achievers and underachievers found all achievers attended college, were more sure of career directions, completed more years of college, and were more involved in campus activities, but did not report more satisfaction with life development since high school than underachievers. (Contains…

Peterson, Jean Sunde

2000-01-01

234

Skin cancer in patients with psoriasis treated with coal tar. A 25-year follow-up study  

Microsoft Academic Search

For many years, crude coal tar has been used for the treatment of psoriasis. The possible carcinogenic effect of crude coal tar and ultraviolet (UV) radiation (Goeckerman regimen), considered individually or in combination, has been of some concern to physicians. A 25-year follow-up study was completed on 280 patients with psoriasis who were hospitalized and treated with crude coal tar

M. R. Pittelkow; H. O. Perry; S. A. Muller; W. Z. Maughan; P. C. OBrien

1981-01-01

235

One-Year Follow-Up of Combined Parent and Child Intervention for Young Children with ADHD  

ERIC Educational Resources Information Center

Efficacies of the Incredible Years (IY) interventions are well-established in children with oppositional defiant disorder (ODD) but not among those with a primary diagnosis of attention-deficit/hyperactivity disorder (ADHD). We sought to evaluate 1-year follow-up outcomes among young children with ADHD who were treated with the IY interventions.…

Webster-Stratton, Carolyn; Reid, M. Jamila; Beauchaine, Theodore P.

2013-01-01

236

Predictors of Sexual Functioning in a Sample of U. S. Marine Recruits: An 11Year Follow-Up Study  

Microsoft Academic Search

We examined predictors of sexual functioning in male and female U. S. Marines (n = 589) assessed longitudinally for approximately 11 years. Multiple domains of sexual functioning (dysfunctional sexual behaviors, sexual frequency, sexual problems, and sexual satisfaction) were assessed at the 11 year follow-up assessment (T5). T5 depressive symptoms emerged as the most robust predictor of all domains of sexual

Michael K. Suvak; Leah A. Brogan; Jillian C. Shipherd

2012-01-01

237

Childhood leukaemia in Europe after Chernobyl: 5 year follow-up.  

PubMed Central

The European Childhood Leukaemia - Lymphoma Incidence Study (ECLIS) is designed to address concerns about a possible increase in the risk of cancer in Europe following the nuclear accident in Chernobyle in 1986. This paper reports results of surveillance of childhood leukaemia in cancer registry populations from 1980 up to the end of 1991. There was a slight increase in the incidence of childhood leukaemia in Europe during this period, but the overall geographical pattern of change bears no relation to estimated exposure to radiation resulting from the accident. We conclude that at this stage of follow-up any changes in incidence consequent upon the Chernobyl accident remain undetectable against the usual background rates. Our results are consistent with current estimates of the leukaemogenic risk of radiation exposure, which, outside the immediate vicinity of the accident, was small.

Parkin, D. M.; Clayton, D.; Black, R. J.; Masuyer, E.; Friedl, H. P.; Ivanov, E.; Sinnaeve, J.; Tzvetansky, C. G.; Geryk, E.; Storm, H. H.; Rahu, M.; Pukkala, E.; Bernard, J. L.; Carli, P. M.; L'Huilluier, M. C.; Menegoz, F.; Schaffer, P.; Schraub, S.; Kaatsch, P.; Michaelis, J.; Apjok, E.; Schuler, D.; Crosignani, P.; Magnani, C.; Bennett, B. G.

1996-01-01

238

A 6-year follow-up study of Cambodian refugee adolescents traumatized as children.  

PubMed

Seventy-three percent of a sample of 46 Cambodian youth interviewed in 1984 and 1987 were reinterviewed in 1990 as part of a pretest for a multisite study of Cambodian refugee trauma now under way. An additional sample of convenience of 38 youth were also interviewed to determine reliability and validity of the diagnostic instruments chosen for the larger study. The DSM-III-R diagnosis of post-traumatic stress disorder (PTSD) was found to persist, but the symptoms appeared less intense over time. In contrast, the prevalence of depression dropped markedly since 1987. Subjects remained largely free of comorbid conditions. Diagnostic reliability and validity were satisfactory. The follow-up sample appeared to be functioning well despite their PTSD profiles. The findings are discussed in light of several current controversies surrounding the concept and measurement of PTSD. PMID:8444775

Sack, W H; Clarke, G; Him, C; Dickason, D; Goff, B; Lanham, K; Kinzie, J D

1993-03-01

239

Three-year follow-up of Drug Abuse Resistance Education (D.A.R.E.).  

PubMed

The long-term effectiveness of D.A.R.E. was assessed by contrasting 9th-grade students who received the program in the 6th grade with others who did not receive the program. Of 38 elementary schools eligible for D.A.R.E. programs, 21 received the program and 17 did not. A follow-up survey assessed central D.A.R.E. concepts such as self-esteem, resistance to peer pressure, delay of experimentation with drugs, and drug use. Employing latent variables to represent the concepts, no significant differences were found between D.A.R.E. participants and controls. The authors discuss attenuation of effects and the generally antidrug context of schools. PMID:10182199

Dukes, R L; Ullman, J B; Stein, J A

1996-02-01

240

Modular cementless cup for total hip arthroplasty: results at 4-year follow-up.  

PubMed

The aim is to perform the assessment of a modular cementless acetabular cup with a tapered internal design for all bearing couplings. In 190 unselected consecutive patients, 207 total hip arthroplasties were implanted. The implants were clinically and radiographically evaluated. Follow-up was 49.7 ± 8.1 months. The average Harris hip score improved from 55.5 ± 5.7 to 94.7 ± 3.4 (P < 0.05). All cups were well-positioned and stable. The Kaplan-Maier cumulative survivorship was 98.5 ± 0.8%. No significant differences have been noted in dividing patients according to the different liner materials (P < 0.005). The study, whose rationale is the novelty of this kind of implant, suggests the efficacy of the Delta-PF acetabular cup. PMID:22223107

Bistolfi, Alessandro; Massazza, Giuseppe; Rosso, Federica; Ventura, Stefano; Lagalla, Francesco; Crova, Maurizio

2012-08-01

241

Bootes 3: first two years of GRB follow-ups in New Zealand  

NASA Astrophysics Data System (ADS)

BOOTES-3 is the first robotic observatory located in the southern hemisphere of the BOOTES (Burst Observer and Optical Transient Exploring System) network. It was inaugurated in February of 2009, beginning its operations promptly after. It's located nearby Blenheim, New Zealand. The main scientific objective is observation and follow-up of the optical counterparts of GRBs (Gamma Ray Bursts), responding to an alert in a quick and completely autonomous manner. For this it is equipped with a high-speed pointing mount (6-10 seconds), and the whole observatory is controlled by the RTS-2 (Remote Telescope System 2) software. Being at Spain's antipode, this observatory complements the coverage of the Spanish BOOTES telescopes.

Tello, J. C.; de Ugarte Postigo, A.; Sánchez-Ramírez, R.; Jelínek, M.; Gorosabel, J.; Kubánek, P.; Cunniffe, R.; Guziy, S.; Allen, W.; Yock, Ph.; Lin, Kuan-Yu; Castro-Tirado, A. J.; Fernández, R.; Pérez del Pulgar, C.

242

Determinants of Aortic Stiffness: 16-Year Follow-Up of the Whitehall II Study  

PubMed Central

Background Aortic stiffness is a strong predictor of cardiovascular disease endpoints. Cross-sectional studies have shown associations of various cardiovascular risk factors with aortic pulse wave velocity, a measure of aortic stiffness, but the long-term impact of these factors on aortic stiffness is unknown. Methods In 3,769 men and women from the Whitehall II cohort, a wide range of traditional and novel cardiovascular risk factors were determined at baseline (1991–1993) and aortic pulse wave velocity was measured at follow-up (2007–2009). The prospective associations between each baseline risk factor and aortic pulse wave velocity at follow-up were assessed through sex stratified linear regression analysis adjusted for relevant confounders. Missing data on baseline determinants were imputed using the Multivariate Imputation by Chained Equations. Results Among men, the strongest predictors were waist circumference, waist-hip ratio, heart rate and interleukin 1 receptor antagonist, and among women, adiponectin, triglycerides, pulse pressure and waist-hip ratio. The impact of 10 centimeter increase in waist circumference on aortic pulse wave velocity was twice as large for men compared with women (men: 0.40 m/s (95%-CI: 0.24;0.56); women: 0.17 m/s (95%-CI: ?0.01;0.35)), whereas the opposite was true for the impact of a two-fold increase in adiponectin (men: ?0.30 m/s (95%-CI: ?0.51;?0.10); women: 0.61 m/s (95%-CI: ?0.86;?0.35)). Conclusion In this large prospective study, central obesity was a strong predictor of aortic stiffness. Additionally, heart rate in men and adiponectin in women predicted aortic pulse wave velocity suggesting that strategies to prevent aortic stiffening should be focused differently by sex.

Brunner, Eric J.; Tabak, Adam G.; Shipley, Martin J.; Wilkinson, Ian B.; McEniery, Carmel M.; Roden, Michael; Herder, Christian; Kivimaki, Mika; Witte, Daniel R.

2012-01-01

243

Excessively high magnetic resonance signal in preterm infants and neuropsychobehavioural follow-up at 2 years.  

PubMed

The diffuse excessive high-signal intensity (DEHSI) findings in the T2 weighted scans of white matter (WM), besides the corresponding low signal in the T1 weighted images, are usually more evident around the periventricular regions. It is not clear whether the DEHSI should be considered as a diffuse WM injury rather than a sign of delayed maturation of the WM. Eighty nine preterm infants at the full-term equivalent age (FEA) were studied using conventional Magnetic Resonance (MR) imaging of the brain. Based on the MR findings, the infants studied were divided into three groups: the control group presenting normal WM, the DEHSI group and the group with other WM lesions. Ten newborns were not included in the statistical analysis because they presented evidence of precedent germinal matrix hemorrhage (GMH-IVH) which cannot be considered as WM lesions. Seventy nine infants were enrolled in a program of neuropsychobehavioural study follow-up until 24 months of age. Each infant was evaluated for those variables which mostly affect the occurrence of neuropsychomotor disability. In the DEHSI infant group, significantly lower mean pH and mean base excess (BE) values were found in comparison to controls, while the mean birth weight (BW) was significantly higher. No significant difference was observed between the mean 1st minute Apgar Score, mean birth gestational age (GA) and assisted ventilation mean duration of controls and DEHSI groups. Finally, no significant difference between the parameters studied was found by comparing the WM lesion infants group to the DEHSI infants one. Our observations, together with follow-up studies, even up to school age, confirm that DEHSI has a clinical significance and cannot be considered as a simple indicator of delayed WM maturation. PMID:15888258

Domizio, S; Barbante, E; Puglielli, C; Clementini, E; Domizio, R; Sabatino, G M D; Albanese, A; Colosimo, C; Sabatino, G

2005-01-01

244

Surgically treated bladder hemangiopericytoma/solitary fibrous tumor: report of a 12-year asymptomatic follow-up.  

PubMed

Hemangiopericytoma (HPC)/solitary fibrous tumor (SFT) is an uncommon vascular tumor suggested to be originating from pericytes. There are few reports on bladder HPC/SFT. We present a case of huge bladder HPC/SFT measuring 13.9 × 12.2 × 11.1 cm with invasion to right iliac vein in a 54-year-old man. The patient underwent radical surgical tumor excision without chemotherapy or radiotherapy. The patient is symptom-free without recurrence or metastasis during the 12-year follow-up period. This case is the longest follow-up reported to date for bladder HPC/SFT. PMID:24022844

Mozafarpour, Sarah; Khorramirouz, Reza; Tajali, Afshin; Salavati, Alborz; Kajbafzadeh, Abdol-Mohammad

2014-03-01

245

One-Year Follow-Up of Combined Parent and Child Intervention for Young Children with ADHD  

PubMed Central

Objective Efficacies of the Incredible Years (IY) interventions are well established in children with oppositional defiant disorder (ODD), but not among those with a primary diagnosis of attention-deficit/hyperactivity disorder (ADHD). We sought to evaluate one-year follow-up outcomes among young children with ADHD who were treated with the IY interventions. Method Four- to six-year-olds with ADHD (n=49, 73% males) participated in six months of treatment using the IY parent and child interventions. Results Immediate post-treatment results indicated improvements in parenting, children’s externalizing and attention problems, and social contact at school. At one-year follow up, 22 of 27 variables that showed significant post-treatment effects demonstrated maintenance to one-year follow up. Children with higher ODD symptoms at baseline showed more improvement in oppositionality and total behavior problems, and their mothers showed more improvement on harsh discipline scores. Approximately 70–75% of children were reported by their parents and teachers to fall below clinical cut-offs on measures of externalizing symptoms at the one-year follow up (compared to 50% at baseline) and more than 50% fell below clinical cut-offs on measures of hyperactivity and inattentiveness (all were in the clinical range at baseline). Conclusions Children with ADHD who were treated with the IY parent and child treatment programs showed maintenance of treatment effects one year after treatment.

Webster-Stratton, Carolyn; Reid, M. Jamila; Beauchaine, Theodore P.

2012-01-01

246

Realities and Challenges of a Five Year Follow Up of Mother and Child Pairs on a PMTCT Program in Zimbabwe  

PubMed Central

Background: Complete follow up is an essential component of observational cohorts irrespective of the type of disease. Objectives: To describe five years follow up of mother and child pairs on a PMTCT program, highlighting loss to follow up (LTFU) and mortality (attrition). Study Design: A cohort of pregnant women was enrolled from the national PMTCT program at 36 weeks gestational age attending three peri urban clinics around Harare offering maternal and child health services. Mother-infant pairs were followed up from birth and twice yearly for five years. Results: A total of 479 HIV infected and 571 HIV negative pregnant women were enrolled, 445(92.9%) and 495(86.6%) were followed up whereas 14(3.0%) and 3(0.5%) died in the 1st year respectively; RR (95%CI) 5.3(1.5-18.7). At five years 227(56.7%) HIV infected and 239(41.0%) HIV negative mothers turned up, whereas mortality rates were 34 and 7 per 100 person years respectively. Birth information was recorded for 401(83.7%) HIV exposed and 441(77.2%) unexposed infants, 247(51.6%) and 232(40.6) turned up in the first year whilst mortality was 58(12.9%) and 22(4.4%) respectively, RR (95%CI) 3.2(2.0-5.4). At five years 210(57.5%) HIV exposed and 239(44.3%) unexposed infants were seen, whilst mortality rates were 53 per 1000 and 15 per 1 000 person years respectively. Mortality rate for HIV infected children was 112 compared to 21 per 1 000 person years for the exposed but uninfected. Conclusion: HIV infected mothers and their children succumbed to mortality whereas the HIV negatives were LTFU. Mortality rates and LTFU are high within PMTCT program.

Kurewa, E.N; Kandawasvika, G.Q; Mhlanga, F; Munjoma, M; Mapingure, M.P; Chandiwana, P; Chirenje, M.Z; Rusakaniko, S; Stray-Pedersen, B

2011-01-01

247

Four year follow-up of a randomised controlled trial comparing open and laparoscopic Nissen fundoplication in children  

PubMed Central

Objective To evaluate the 4-year results following a randomised controlled trial (RCT) comparing open (ONF) and laparoscopic (LNF) Nissen fundoplication in children. Background It is assumed that long-term results of ONF and LNF are comparable. No randomised studies have been performed in children. Methods A follow-up study was performed in children randomised to ONF or LNF (clinicaltrials.gov identifier NCT00259961). Recurrent gastro-oesophageal reflux (GER) was documented by upper gastrointestinal contrast study and/or 24-h pH study. Nutritional status, retching and other symptoms were investigated. A questionnaire was used to assess the quality of life before and after surgery. Results Thirty-nine children were randomised to ONF (n=20) or LNF (n=19). There were 15 ONF and 16 LNF neurologically impaired children. One patient (ONF group) was lost to follow-up. Follow-up was 4.1?years (3.1–5.3) for ONF group and 4.1?years (2.6–5.1) for LNF group (p=0.9). Seven neurologically impaired children had died by the time of follow-up (3 ONF, 4 LNF). Incidence of recurrent GER was 12.5% in the ONF and 20% in the LNF (p=ns). One patient in each group underwent redo-Nissen fundoplication. Nutritional status improved in both groups, as indicated by a significant increase in weight Z-score (p<0.01). Gas bloat and dumping syndrome were present in both groups (p=ns). Incidence of retching was lower in the laparoscopic group (p=0.01). Quality of life improved in both groups (p=ns). Conclusions Open and laparoscopic Nissen provide similar control of reflux and quality of life at follow-up. LNF is associated with reduced incidence of retching persisting at 4-year follow-up. Trial registration number NCT00259961.

Pacilli, Maurizio; Eaton, Simon; McHoney, Merrill; Kiely, Edward M; Drake, David P; Curry, Joseph I; Lindley, Keith J; Pierro, Agostino

2014-01-01

248

Modern dual-mobility cup implanted with an uncemented stem: about 100 cases with 12-year follow-up.  

PubMed

We report the results of a 12-year follow-up retrospective series of 100 total hip arthroplasties using cementless, press-fit, dual-mobility acetabular cups. The aim of our study was to evaluate the clinical and radiographic results of this acetabular cup at last follow-up. This continuous and homogeneous series included 100 primary total hip arthroplasties performed during the year 2000. The THA combined a Corail® stem (Corail®, Depuy, Warsaw, IN) with a stainless steel Novae Sunfit® (Serf, Decines, France) acetabular cup. Fifteen patients died and 2 were lost to follow-up. Two cases of early dislocation were observed, and 3 cases of aseptic loosening of the acetabular component were reported. The mean stem subsidence was 0.71 mm, the mean craniopodal acetabular migration was 1.37 mm, and the mean medio-lateral acetabular migration was 1.52 mm. The 12-year survivorship is comparable to the data from the literature. The low dislocation rate at 12 years confirms the long-term, high stability of dual mobility, which should be recommended in primary THA for patients at risk for postoperative instability. The absence of true intraprosthetic dislocation events at 12-year follow-up provides evidence of the good quality of the latest generation of polyethylene liners and the necessity of combining thin-mirror, polished femoral necks with dual-mobility cups. PMID:23686801

Philippot, Remi; Meucci, Jean Francois; Boyer, Bertrand; Farizon, Frederic

2013-09-01

249

Thirteen years follow-up of heart myxoma operated patients: what is the appropriate surgical technique?  

PubMed Central

Background Cardiac myxoma is a benign neoplasm that represents the most prevalent primary tumor of the heart. If not treated with the right surgical technique recurrence occurs. Aim of our study is to present our surgical approach and the histology of the tumors resected. Methods All patients, except for one, underwent extracorporeal circulation and mild hypothermia, right atrial or both atrial incision and excision of the fossa ovalis, followed by prosthetic patch suturing. All specimens were submitted for microscopic evaluation (haematoxylin-eosin). We contacted personally each patient and asked them to complete a standardized questionnaire, concerning their peri-operative characteristics. Results Six cases were “active” myxomas, 3 were “mildly active” and 3 were “inactive”. “Normal differentiation” was seen in 6, “medium” in 1 and “poor” in 5 cases. In our series there were no recurrences recorded during the follow-up period. Conclusions The ideal approach, according to our experience is right atrial or both atrial incision as described by Shumacker and King, with excision of the fossa ovalis and the surrounding tissues and closure with a pericardial patch. Such a technique provides an excellent long-term survival in these patients.

Siminelakis, Stavros; Kakourou, Alexandra; Batistatou, Alexandra; Sismanidis, Stelios; Ntoulia, Alexandra; Tsakiridis, Kosmas; Syminelaki, Theodora; Apostolakis, Eleftherios; Tsiouda, Theodora; Katsikogiannis, Nikolaos; Kougioumtzi, Ioanna; Dryllis, Georgios; Machairiotis, Nikolaos; Mpakas, Andreas; Beleveslis, Thomas; Zarogoulidis, Konstantinos

2014-01-01

250

Hypofractionation in post-mastectomy breast cancer patients: seven-year follow-up.  

PubMed

To compare three fractionation schedules in post-mastectomy patients treated with radiotherapy as regard acute and early late effects as well as local recurrence rates. One hundred and seven breast cancer patients treated with modified radical mastectomy and adjuvant radiotherapy±adjuvant systemic treatments between November 2001 and July 2004 were enrolled in this study. Patients were categorized into three groups. Group A (41 patients) received conventional fractionation 50 Gy over 25 fractions. Group B (36 patients) received other fractionation regimen 45 Gy over 17 fractions. Group C (30 patients) received 40 Gy over 15 fractions. The median follow-up period was 23 months. There has been no statistical significant difference in local control (P=0.88), pain (P=0.98), telangectasis (P=0.23), fibrosis (P=0.13), arm oedema (P=0.96) or pigmentation (P=0.80) between the three groups. GII-III Erythema was significantly higher in the two hypofractionation arms compared to the control arm (P=0.001). Although acute skin reactions were higher in the hypofractionated arms, there was no significant difference in the local recurrence rates or late radiation effects. A national randomized multicentre study is recommended to explore this further. PMID:22354766

Eldeeb, Hany; Awad, Iman; Elhanafy, Osman

2012-12-01

251

Inpatient rehabilitation for hip or knee osteoarthritis: 2 year follow up study  

PubMed Central

Objective: To examine the course of pain, physical function, and other health dimensions after a comprehensive inpatient rehabilitation intervention in patients with osteoarthritis (OA) of the hip or knee. Methods: An observational, prospective cohort study with assessments at baseline (entry into clinic), 1 (discharge from inpatient rehabilitation), 3, 6, 9, 12, and 24 months after baseline. Consecutively referred patients to an inpatient rehabilitation centre fulfilling the inclusion criteria were studied. 3–4 week comprehensive rehabilitation intervention, including strengthening exercise, flexibility training, endurance training, relaxation strategies, and consultations for preventive measures, was carried out. Individual home rehabilitation programmes were taught. Generic health status was measured using the SF-36, condition specific health was measured with the WOMAC questionnaire. Effects were analysed with sensitivity statistics (effect size, ES) and non-parametric tests. Results: Data from 128 patients with complete follow up data were analysed. Both pain and physical function improved moderately (WOMAC pain: ES = 0.56, WOMAC function ES = 0.44) until discharge. Although the effect in pain reduction remained significant by month 24 (WOMAC: ES = 0.26), physical function deteriorated close to baseline values after 12 months. Conclusions: Comprehensive inpatient rehabilitation of patients with OA of the hip or knee may improve pain and physical function in the mid-term, and pain in the long term.

Weigl, M; Angst, F; Stucki, G; Lehmann, S; Aeschlimann, A

2004-01-01

252

Natural course of LGI1 encephalitis: 3-5years of follow-up without immunotherapy.  

PubMed

Antibodies against LGI1 (leucin-rich glioma-inactivated 1 protein) are associated with limbic encephalitis (LE), which is characterized by a favorable outcome following immunotherapy. Here, we present two cases, where antibodies against LGI1 were detected in the sera 36 and 53months after acute LE, respectively, and none of the patients received immunotherapy. LE showed characteristics of LGI1 encephalitis in both cases, including low sodium content in the sera; disorientation, hallucination, short-term memory loss; and epileptic seizures. One patient had faciobrachial tonic seizures. MRI indicated bilateral inflammation of the hippocampus in one case. We reviewed longitudinal clinical and MRI data covering 53 and 36months after LE without immunotherapy, respectively. Both patients became seizure-free and spontaneously recovered with mild/moderate cognitive impairment. No relapses have been observed. Follow-up brain MRI indicated early hippocampal sclerosis and global brain atrophy in one case characterized by more pronounced cognitive deficit. Memory and verbal fluency were affected most during the natural course of LGI1 encephalitis. LGI1 encephalitis had a monophasic course and spontaneously improved, suggesting that a relatively benign natural course may contribute to the favorable outcome observed after immunotherapy. Our data also indicate that LGI1 antibodies can be present in the sera without clinical disease activity. PMID:24928080

Szots, Monika; Marton, Annamaria; Kover, Ferenc; Kiss, Tunde; Berki, Timea; Nagy, Ferenc; Illes, Zsolt

2014-08-15

253

Olfactory function following nasal surgery: a 1-year follow-up.  

PubMed

Olfactory dysfunction is a frequent symptom of nasal and sinunasal disease. Many of these patients undergo nasal sinus or nasal septum surgery. In this study, we evaluated the benefit of nasal surgery on olfactory function over a period of 12 months. Patients included in this study underwent either nasal sinus or nasal septum surgery. All patients were tested for olfactory function using the "Sniffin' sticks" 16 item odor identification test. In addition, patients were asked to rate their nasal patency as well as their olfactory function at each visit. 157 patients were tested 3.5 months after surgery and 52 patients were tested again 12 months after surgery. Olfactory function improved significantly 3.5 months after surgery in patients, who received nasal sinus surgery; no significant increase was found in patients treated with nasal septum surgery. At the 12-month follow-up, the increase in olfactory function over all patients just missed statistical significance. Individually, however, 19% of the patients exhibited improvement after 3.5 months and 17% after 12 months. These numbers increased in patients with rhinosinusitis with nasal polyps, who exhibited improvement of 30% after 3.5 months, and 32% after 12 months. Nasal sinus surgery produced an increase in measured olfactory function, but not nasal septum surgery. This increase appeared to be stable over the examined period of 12 months. PMID:22382399

Schriever, V A; Gupta, N; Pade, J; Szewczynska, M; Hummel, T

2013-01-01

254

Five to eight years follow-up for trapeziectomy and Weilby ligament reconstruction for the treatment of trapeziometacarpal osteoarthritis.  

PubMed

Trapeziectomy and Weilby ligament reconstruction is a recognized treatment for osteoarthritis of the trapeziometacarpal joint. Studies published using this procedure have limited follow-up post-surgery. In this series of 24 cases assessed objectively and 36 subjectively with a minimum follow-up of five years, patients continue to have pain relief and function comparable to the opposite non-operated hand. Patient satisfaction is high at 92% and the rate of complications is low. Despite these encouraging results the need for interposition arthroplasty and/or ligament reconstruction in addition to trapeziectomy alone is discussed. PMID:24156580

Bidwai, A S C; Marlow, W J; Khan, Y; Waseem, M

2013-01-01

255

Life Satisfaction, Illness Behaviour, and Rehabilitation Outcome: Results of a One Year Follow-Up Study with Cardiac Patients.  

ERIC Educational Resources Information Center

Follow-up study one year after an inpatient cardiac rehabilitation program of 83 male cardiac patients found reported life satisfaction generally lower with increased physical complaints and emotional lability. Of patients originally identified as having high life satisfaction, 90 percent were back at work compared to 66 percent of patients with…

Myrtek, Michael

1987-01-01

256

1990 Follow-up of Former JCCC Students Currently Enrolled at Four-Year Colleges or Universities: A Transfer Study.  

ERIC Educational Resources Information Center

In 1990, a follow-up study was conducted of former Johnson County Community College (JCCC) students who transferred to four-year colleges and universities during 1989. The study sought to provide information concerning JCCC's role in preparing students for transfer, assess students' perceptions of their educational experiences at JCCC, and gather…

Johnson County Community Coll., Overland Park, KS. Office of Institutional Research.

257

Methods and Measures Used for Follow-up at 15 Years of the English and Romanian Adoptee (ERA) Study  

ERIC Educational Resources Information Center

This chapter covers the methods and measures used in the ERA study, with a special focus on age 15 outcomes. First, the authors outline the sample participation rate for the 15-year follow-up--the percentages in all cases referring to the numbers at the time of initial sample contact. They then describe the measures used in this monograph,…

Monographs of the Society for Research in Child Development, 2010

2010-01-01

258

Trans-Obturator Vaginal Tape (TOT ®) for Female Stress Incontinence: One Year Follow-Up in 120 Patients  

Microsoft Academic Search

Objectives:The aim of this study was to evaluate the effectiveness of a new minimally invasive surgical procedure, the Trans-obturator Vaginal Tape (TOT®) in the treatment of female urodynamic stress incontinence (USI) and to analyse functional results and quality of life after one year of follow up.

Thierry Roumeguère; Th. Quackels; R. Bollens; A. de Groote; A. Zlotta; M. Vanden Bossche; C. Schulman

2005-01-01

259

Do pain problems in young school children persist into early adulthood? A 13-year follow-up  

Microsoft Academic Search

Design. In a longitudinal study, 335 children ages 8, 11 and 14, first studied in 1989 were followed-up on two occasions in 1991 and 2002. The subjects filled in questionnaires on pain, the first two times in school, the last as a postal survey.Purposes. To determine if headache and back pain during the school years were transitory or if they

Gunilla Brattberg

2004-01-01

260

Combined Individual Cognitive Behavior Therapy and Parent Training for Childhood Depression: 2- to 3-Year Follow-up  

ERIC Educational Resources Information Center

Fourteen children with significant depressive symptoms from an open clinical trial of Primary and Secondary Control Enhancement Training augmented with Caregiver-Child Relationship Enhancement Training, participated in a 2- to 3-year follow-up assessment. The results suggested that the significant decreases in depressive symptoms observed at…

Eckshtain, Dikla; Gaynor, Scott T.

2013-01-01

261

Pituitary Stalk Hemangioblastoma in a von Hippel-Lindau Patient : Clinical Course Follow-Up Over a 20-Year Period  

PubMed Central

Supratentorial hemangioblastomas (HBs) are rare, and pituitary stalk HBs are extremely uncommon; therefore, pituitary stalk evaluation is often overlooked. Herein, we report the development of pituitary stalk HB over a 20-year period and the importance of regular long-term follow up for patients with HBs.

Lee, Kyung Mi; Choi, Woo Suk; Kim, Tae Sung

2013-01-01

262

Elderly Handicapped Persons in a Primary Care District: Changes during a 5-8 Year Follow-Up.  

ERIC Educational Resources Information Center

A 1975-76 Swedish study of 643 handicapped persons born in 1918 or earlier and a follow-up study conducted 5-8 years later found a higher mortality rate than the general mortality in the same age group. Population changes are described, focusing on institutionalization, need for services, functional level, hearing, and vision. (Author/JDD)

Samuelsson, Gillis; Dehlin, Ove

1987-01-01

263

Outcomes of minimally 1 year follow-up for the arthroscopic Remplissage technique with Hill-Sachs lesion  

PubMed Central

Purpose We evaluated minimal 1 year follow-up results for the Remplissage technique to fill a Hill–Sachs lesion with anterior instability. Methods The subjects were 12 patients, who could be followed-up for more than 12 months after the ”Remplissage” procedures in our hospital from August 2008 to May 2010. Their mean age was 28.6 years old and the mean follow-up was 19 months. The evaluations included the ROM, the ASES score, the KSSI score, the ROWE score and postoperative MRI. Results On the postoperative functional evaluation after an average 16 months, the ASES score improved 51.4 in preoperative to 86.6 in postoperatively, the KSSI score improved from 46.6 preoperatively to 84.9 postoperatively and the ROWE score improved from 43.6 preoperatively to 91.4 postoperatively. After an average 14 months for all the cases, the range of movement was nearly in the normal range which is 174.3 ± 5.04 (170–180) degrees in foreward flexion, and 56.4 ± 9.60 (50–60) degrees in external rotation. Conclusion For recurrent shoulder instability with a large Hill–Sachs lesion, the Remplissage technique has a good outcome after more than 1 year follow-up in terms of shoulder stability, and the clinical and functional results. Level of evidence Level IV, therapeutic case series

Ko, Sang-Hun; Shin, Seung-Myeong; Jo, Beom-Geon

2013-01-01

264

Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial.  

PubMed

Remission and recovery are major outcome goals in schizophrenia yet their predictors have not been studied in detail. Therefore, 186 patients were examined regarding remission and recovery including their potential sociodemographic and clinical predictors 1 year after discharge. Remission was defined according to the consensus remission criteria and recovery following the definition by Liberman et al. (2002). Of the 186 patients 54% achieved remission and 26% recovery at the 1-year follow-up. The remission status at discharge was found to significantly influence remission and recovery at follow-up. A higher SOFAS score (P = 0.0002) as well as a positive attitude towards treatment at discharge (P = 0.0038) were identified to be significant predictors of remission at 1-year follow-up. Having a job (P = <0.0001) and being without pharmacological treatment at follow-up (P = 0.0113) were found to be significantly predictive of recovery. Our results underline the need to implement more specific treatment strategies to improve long-term outcome. PMID:22038270

Schennach, Rebecca; Riedel, Michael; Obermeier, Michael; Jäger, Markus; Schmauss, Max; Laux, Gerd; Pfeiffer, Herbert; Naber, Dieter; Schmidt, Lutz G; Gaebel, Wolfgang; Klosterkötter, Joachim; Heuser, Isabella; Maier, Wolfgang; Lemke, Matthias R; Rüther, Eckart; Klingberg, Stefan; Gastpar, Markus; Seemüller, Florian; Möller, Hans-Jürgen

2012-06-01

265

Acetabular revision total hip arthroplasty using an impacted morselized allograft and a cementless cup: minimum 10-year follow-up.  

PubMed

This study was undertaken to analyze the clinical and radiologic results of acetabular revision arthroplasty using an impacted morselized allograft and a cementless cup and was performed on 71 hips of 62 patients who were followed up for a minimum of 10 years (10 years to 14 years 8 months; mean, 12 years). The acetabular bone defects were classified using the American Academy of Orthopaedic Surgeons Committee on the Hip and Paprosky classifications. Cementless hemispherical cups were inserted via a press-fit technique, using an impacted morselized allograft. The mean Harris hip score at the last follow-up visit was 92. Only 3 cases were re-revised, and the 12-year survival rate was thus 95.8%. The study shows that acetabular revision arthroplasty using an impacted morselized allograft and a cementless cup is an excellent treatment option. PMID:21592720

Lee, Joong-Myung; Nam, Hee-Tae

2011-10-01

266

Gamma-knife radiosurgery in acromegaly: a 4-year follow-up study.  

PubMed

Stereotactic radiosurgery by gamma-knife (GK) is an attractive therapeutic option after failure of microsurgical removal in patients with pituitary adenoma. In these tumors or remnants of them, it aims to obtain the arrest of cell proliferation and hormone hypersecretion using a single precise high dose of ionizing radiation, sparing surrounding structures. The long-term efficacy and toxicity of GK in acromegaly are only partially known. Thirty acromegalic patients (14 women and 16 men) entered a prospective study of GK treatment. Most were surgical failures, whereas in 3 GK was the primary treatment. Imaging of the adenoma and target coordinates identification were obtained by high resolution magnetic resonance imaging. All patients were treated with multiple isocenters (mean, 8; range, 3-11). The 50% isodose was used in 27 patients (90%). The mean margin dose was 20 Gy (range, 15-35), and the dose to the visual pathways was always less than 8 Gy. After a median follow-up of 46 months (range, 9-96), IGF-I fell from 805 micro g/liter (median; interquartile range, 640-994) to 460 micro g/liter (interquartile range, 217-654; P = 0.0002), and normal age-matched IGF-I levels were reached in 7 patients (23%). Mean GH levels decreased from 10 micro g/liter (interquartile range, 6.4-15) to 2.9 micro g/liter (interquartile range, 2-5.3; P < 0.0001), reaching levels below 2.5 micro g/liter in 11 (37%). The rate of persistently pathological hormonal levels was still 70% at 5 yr by Kaplan-Meier analysis. The median volume was 1.43 ml (range, 0.20-3.7). Tumor shrinkage (at least 25% of basal volume) occurred after 24 months (range, 12-36) in 11 of 19 patients (58% of assessable patients). The rate of shrinkage was 79% at 4 yr. In no case was further growth observed. Only 1 patient complained of side-effects (severe headache and nausea immediately after the procedure, with full recovery in a few days with steroid therapy). Anterior pituitary failures were observed in 2 patients, who already had partial hypopituitarism, after 2 and 6 yr, respectively. No patient developed visual deficits. GK is a valid adjunctive tool in the management of acromegaly that controls GH/IGF-I hypersecretion and tumor growth, with shrinkage of adenoma and no recurrence of the disease in the considered observation period and with low acute and chronic toxicity. PMID:12843150

Attanasio, Roberto; Epaminonda, Paolo; Motti, Enrico; Giugni, Enrico; Ventrella, Laura; Cozzi, Renato; Farabola, Mario; Loli, Paola; Beck-Peccoz, Paolo; Arosio, Maura

2003-07-01

267

Long-term outcome in epilepsy with grand mal on awakening: forty years of follow-up.  

PubMed

Epilepsy with grand mal on awakening (EGMA) is a well-defined subtype of idiopathic generalized epilepsy. Patients with follow-up of at least 20 years were assessed retrospectively regarding 5-year terminal seizure remission. Forty-two patients were included (mean age=60 ± 13 years). After follow-up of 40 ± 13 years, 26 patients (62%) were in remission, 5 without antiepileptic drugs. Age at investigation (odds ratio=0.939, 95% confidence interval=0.887-0.994, p=0.029) independently predicted lacking remission. Nineteen patients (45.2%) had withdrawn from antiepileptic drugs at least once; 12 of those (63.2%) had seizure relapse. EGMA has a favorable long-term prognosis. With increasing age and treatment duration, antiepileptic drug withdrawal may be justified. PMID:24395517

Holtkamp, Martin; Kowski, Alexander B; Merkle, Hannah; Janz, Dieter

2014-02-01

268

Treatment of Visceral Aneurysm Using Multilayer Stent: Two-Year Follow-Up Results in Five Consecutive Patients  

SciTech Connect

Purpose: The present study was performed to analyze the midterm results (five consecutive patients, 2-year follow-up) of the endovascular management of visceral artery aneurysms using the Cardiatis Multilayer Flow Modulator (CMFM) (Cardiatis, Isnes, Belgium), a self-expandable stent. Materials and Methods: From August 2009 to January 2011, we implanted five CMFMs in five patients (all men; mean age 73 years) to treat two common hepatic artery aneurysms, one celiac trunk aneurysm, one splenic artery aneurysm, and one superior mesenteric artery aneurysm (diameter 25-81 mm). The primary end point was technical success. The secondary end point was stent patency, absence of aneurysm rupture or reperfusion, and shrinking of the sac at 6-, 12-, and 24-month follow-up using computed tomography angiography. Follow-up ranged from 24 to 48 months (mean 31.2). Results: Technical success was achieved in all patients. Complete exclusion of the aneurysm with sac shrinking was achieved in two patients. Two stents became occluded at 6- and 24-month follow-up, respectively; both patients were asymptomatic and were not retreated. One patient developed sac reperfusion due to incomplete aneurysm exclusion. Conclusion: Long-term results in a wider population are needed to validate the effectiveness of the CMFM.

Balderi, Alberto, E-mail: balders@libero.it; Antonietti, Alberto, E-mail: antonietti.a@ospedale.cuneo.it; Pedrazzini, Fulvio, E-mail: pedrazzini.f@ospedale.cuneo.it; Sortino, Davide, E-mail: davide.sortino@hotmail.it; Vinay, Claudia, E-mail: claudia.vinay@gmail.com; Grosso, Maurizio, E-mail: grosso.m@ospedale.cuneo.it [AO Santa Croce e Carle Hospital, Department of Radiology (Italy)] [AO Santa Croce e Carle Hospital, Department of Radiology (Italy)

2013-10-15

269

Predictors of attrition among children born in a PMTCT programme in Zimbabwe followed up over 5 years.  

PubMed

Eliminating of paediatric HIV within prevention of mother to child transmission (PMTCT) interventions rests on complete follow-up of all children. We report on predictors of child attrition in the PMTCT cascade over 5 years where 1050 pregnant women were enrolled at 36 gestational weeks. Mother and child pairs were followed up at birth, 6 weeks, 4 months, 9 months, and every 6 months thereafter for 60 months. Higher attrition was observed for children of economically advantaged, socially stable mothers regardless of HIV status, whereas compliance was observed for children whose mothers tested positive for HIV-1, HSV-2 and Syphilis. Low birthweight was associated with attrition regardless of maternal HIV status. Five years predictors of attrition did not differ by maternal HIV status, as HIV-exposed children succumbed to mortality and those not exposed were loss to follow-up (LFU). Child follow-up is influenced more by maternal lifestyle and health risks leading to retention of high-risk children in PMTCT programmes. PMID:22262677

Kurewa, Nyaradzai E; Gumbo, Felicity Z; Mapingure, Paul M; Munjoma, Marshall W; Chirenje, Mike Z; Rusakaniko, Simbarashe; Stray-Pedersen, Babill

2012-10-01

270

Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study  

PubMed Central

Background The purpose of this study was to evaluate the visual outcome of photorefractive keratectomy (PRK) in patients with mild to moderate stable keratoconus and to assess the risk of progression of the disease after the excimer laser procedure. Methods In this prospective study, carried out at the Clemenceau Medical Center, an affiliate of Johns Hopkins International, in Beirut, Lebanon, 119 eyes from 72 patients with grade 1–2 keratoconus (Amsler–Krumeich classification) underwent PRK. Forty-seven patients had both eyes treated and 25 patients had one eye treated. The procedure was done using the Wavelight Eye Q Excimer laser. Uncorrected and best-corrected visual acuity, corneal topography, and pachymetry were assessed before the procedure and 3, 6, 12, 36, and 60 months after the procedure. Results Mean uncorrected visual acuity showed a statistically significant improvement (P < 0.05) at one, 3, and 5 years follow-up. One hundred and seventeen eyes (98.3%) showed no progression while two eyes (1.7%) showed progression of the disease at 5 years follow-up, as documented by corneal topography and pachymetry. These two eyes were treated with corneal collagen crosslinking. Conclusion PRK in mild to moderate keratoconus is a safe and effective procedure for improving uncorrected vision in patients with mild refractive errors. However, close follow-up of patients is needed to detect any progression of the disease. Longer follow-up is needed to assess the overall effect of this procedure on progression of the disease.

Chelala, Elias; Rami, Hala El; Dirani, Ali; Fadlallah, Ali; Fakhoury, Omar; Warrak, Elias

2013-01-01

271

Prosthetic valve replacement in Ebstein's malformation: 30-year follow-up.  

PubMed

This report addresses a 42-year-old asymptomatic patient who underwent prosthetic replacement of his tricuspid valve 31 years previously for Ebstein's malformation. A ball valve prosthesis was implanted to replace the abnormal valve. Furthermore, he had concomitant closure of a large atrial septal defect with a perforated patch together with plication of the atrialized ventricular segment. The patient is asymptomatic, and it remains noteworthy that he has not been on coumadin for about 30 years. PMID:10475428

John, S; Rao, C

1999-08-01

272

Periurethral collagen injection for the treatment of female stress urinary incontinence: 4-year follow-up results  

Microsoft Academic Search

Objectives. To assess the long-term (4-year) follow-up of urethral submucosal collagen injection for the treatment of stress urinary incontinence (SUI). Submucosal collagen injections are an acceptable alternative to surgery in the treatment of selected cases of SUI. Most published studies report 1 to 2-year results, with long-term data still being questioned despite the low morbidity and cost-effectiveness of this relatively

J Corcos; C Fournier

1999-01-01

273

Interspinous Process Decompression With the X-STOP Device for Lumbar Spinal Stenosis A 4Year Follow-Up Study  

Microsoft Academic Search

X-STOP is the first interspinous process decompres- sion device that was shown to be superior to nonoperative therapy in patients with neurogenic intermittent claudication secondary to spinal stenosis in the multicenter randomized study at 1 and 2 years. We present 4-year follow-up data on the X-STOP patients. Patient records were screened to identify potentially eligible subjects who underwent X-STOP implanta-

Dimitriy G. Kondrashov; Matthew Hannibal; Ken Y. Hsu; James F. Zucherman

274

Total hip arthroplasty using an uncemented femoral component with taper design: outcome at 10-year follow-up  

Microsoft Academic Search

The aim of this study was to assess the clinical and radiological outcome of the cementless-system (CLS) femoral component\\u000a designed by Spotorno with a taper design. Ninety-four patients (107 hips) were operated on from January 1987 to December 1988.\\u000a The female\\/male ratio was 2\\/1, the mean age was 51 years (range 20–77 years). Clinical follow-up was obtained in 89 hips

M. Schramm; F. Keck; D. Hohmann; R. P. Pitto

2000-01-01

275

Association of reduction in parental overweight with reduction in children's overweight with a 3-year follow-up  

Microsoft Academic Search

Background. Parental overweight has been reported to be a risk factor predicting obesity of their children. However, the effect of changes in parental overweight on the changes in children's overweight is not yet characterized.Methods. Six hundred five children of 9–10 years underwent physical examinations and a survey concerning parents' body mass index (BMI) with a 3-year follow-up.Results. In families where

Akira Kanda; Yoshiki Kamiyama; Takeshi Kawaguchi

2004-01-01

276

Clinical results of meniscus repair with the meniscus arrow: a 4- to 8-year follow-up study  

Microsoft Academic Search

The short-term clinical results of meniscus repair with the meniscus arrow were promising. Unfavorable outcomes were reported\\u000a in two studies, with longer follow-up, raising concerns about the efficacy of this device. We retrospectively reviewed 62\\u000a patients (mean age 23.7 years; range 14–37 years) that underwent all-inside meniscus repair, using the meniscus arrow. Seventeen\\u000a patients had an isolated meniscus tear (ACL intact group)

Nikolaos Koukoulias; Stergios Papastergiou; Konstantinos Kazakos; Georgios Poulios; Konstantinos Parisis

2007-01-01

277

Predictors of Sexual Functioning in a Sample of U.S. Marines: An 11Year Follow-Up Study  

Microsoft Academic Search

We examined predictors of sexual functioning in male and female U.S. Marines (n = 589) assessed longitudinally for approximately 11 years. Multiple domains of sexual functioning (dysfunctional sexual behaviors, sexual frequency, sexual problems, and sexual satisfaction) were assessed at the 11-year follow-up assessment (T5). T5 depressive symptoms emerged as the most robust predictor of all domains of sexual functioning. Different

Michael K. Suvak; Leah A. Brogan; Jillian C. Shipherd

2012-01-01

278

Children of divorce: report of a ten-year follow-up of early latency-age children.  

PubMed

Findings from a ten-year follow-up of 38 youngsters now 16 to 18 years old, whose parents divorced during the children's early latency, suggest that separation from families and the transition into young adulthood are burdened by fear of disappointment in love relationships, lowered expectations, and a sense of powerlessness. A need for the father, especially among boys, appears to burgeon at middle and late adolescence. PMID:3591906

Wallerstein, J S

1987-04-01

279

Anterior cruciate ligament reconstruction with quadrupled semitendinosus tendon - minimum 6 year clinical and radiological follow-up.  

PubMed

This clinical study evaluates the minimum 6 year follow-up clinical, functional, radiological and isometric results after arthroscopic reconstruction of the anterior cruciate ligament (ACL) with quadrupled semitendinosus tendon autograft (femoral endobutton and tibial suture disc fixation). Seventy out of 85 operated patients (lost to follow-up 17%) with an average age of 34.3 years could be clinically examined at a mean follow-up time of 6 years and 4 months after surgery. Results revealed a high subjective satisfaction rate of 93%. The preoperative activity level could be maintained in 71% of the patients. The Lysholm score showed very good and good results in 85% with a mean of 83.6%. Normal or nearly normal results on the IKDC score were reported in 85% of the patients. The KT-1000 arthrometer stability testing showed a difference of less than 3 mm compared to the contralateral knee in 75% of the patients. Five patients (7%) had a graft failure during follow-up time. There were no or only mild degenerative changes at the radiographic evaluation in 85% of the patients. In 15% of the patients a femoral and in 40% a tibial tunnel widening of more than 50% was observed, however without a relevance for the clinical and functional status. Midterm results obtained in this study after arthroscopic ACL reconstruction with the quadrupled semitendinosus tendon confirm the outcomes in the literature after shorter follow-up periods that provide very good and good subjective, functional and stability results in about 80-85% of the patients. This surgical technique can be recommended for the active patient with ACL deficiency. However, patients must be informed that activity level cannot always be maintained and a failure rate of 5-10% must be taken into account in the longer term when decision for surgery is made. PMID:17512735

Buchner, Matthias; Schmeer, Thorsten; Schmitt, Holger

2007-08-01

280

Nutritional risk and survival in elderly veterans: A five-year follow-up  

Microsoft Academic Search

The purpose of this study was to identify predictors of survival over five years in a sample of 377 elderly (age 55+) chronically ill men. Subjects were selected at baseline from consecutive appointments at a geriatric clinic and given extensive medical and psychosocial assessment. Five years later, subjects who could be located were interviewed by telephone. Interviews were completed with

Rodney M. Coe; James C. Romeis; Douglas K. Miller; Fredric D. Wolinsky; Katherine S. Virgo

1993-01-01

281

Recovery of Functional Impairment after Acute Illness and Mortality: One-Year Follow-Up Study  

Microsoft Academic Search

Background: Functional status in older people is a dynamic situation, which makes it necessary to evaluate functional capacity at different times to determinate their prognostic value. Objective: To examine the association between functional status (baseline and change after acute illness) and mortality and functional changes at 1 year. Methods: Hospital-based prospective longitudinal cohort study of all patients over 65 years

Juan J. Baztán; César P. Gálvez; Alberto Socorro

2009-01-01

282

Substance Use and Abuse among Adolescent Runaways: A Four-Year Follow-Up Study.  

ERIC Educational Resources Information Center

Using National Longitudinal Study Youth Survey data for 1,241 males and 1,143 females, runaway status in early adolescence--ages 14-15 years--was associated with subsequent--4 years later--substance abuse, alcohol problems, and school-dropout status. Gender and number of runaway episodes were considered. Repeat-runaways reported higher substance…

Windle, Michael

1989-01-01

283

Cognitive and Psychiatric Predictors to Psychosis in Velocardiofacial Syndrome: A 3-Year Follow-Up Study  

ERIC Educational Resources Information Center

Objective: To predict prodromal psychosis in adolescents with velocardiofacial syndrome (VCFS). Method: A total of 70 youth with VCFS, 27 siblings of youth with VCFS, and 25 community controls were followed from childhood (mean age = 11.8 years) into mid-adolescence (mean age = 15.0 years). Psychological tests measuring intelligence, academic…

Antshel, Kevin M.; Shprintzen, Robert; Fremont, Wanda; Higgins, Anne Marie; Faraone, Stephen V.; Kates, Wendy R.

2010-01-01

284

Follow-up study of bedwetting from 3 to 5 years of age  

Microsoft Academic Search

Objectives. To evaluate the relationship between bedwetting and development in infancy.Methods. Questionnaires concerning micturition habits and development at 3 and 5 years of age were completed by the parents of 157 children who had had their health checked by pediatricians at a group checkup at 3 years of age.Results. The percentage of bedwetters in whom the frequency of bedwetting was

Akihiro Kawauchi; Yoshiyuki Tanaka; Yutaka Yamao; Mitsuhiko Inaba; Motohiro Kanazawa; Osamu Ukimura; Yoichi Mizutani; Tsuneharu Miki

2001-01-01

285

Brief Report: 25-Year Follow-Up of a High-Functioning Autistic Child  

ERIC Educational Resources Information Center

The following case report based on a 25-year experience with a high-functioning autistic child is offered (1) to provide some historical perspective on our approaches to ASD over the past 25 years, and (2) to illuminate some areas of continuing need for improvement.

Bolman, William M.

2008-01-01

286

A Study of Variables Relating to Women's Vocational Patterns: A Fifteen Year Follow-Up.  

ERIC Educational Resources Information Center

A Vocational Pattern Index, based on Zytowski's (1969) postulates on women's vocational participation, was developed. This index is based on age of first entry into the job market, number of entries, years of work, and degree of participation. Fifteen years after graduation from the University of Minnesota, a Questionnaire requesting detailed…

Kummerow, Jean M.; Hummel, Thomas J.

287

Time Keeping and Working Memory Development in Early Adolescence: A 4-Year Follow-Up  

ERIC Educational Resources Information Center

In this longitudinal study, we examined time keeping in relation to working memory (WM) development. School-aged children completed two tasks of WM updating and a time monitoring task in which they indicated the passing of time every 5 min while watching a film. Children completed these tasks first when they were 8 to 12 years old and then 4 years

Forman, Helen; Mantyla, Timo; Carelli, Maria G.

2011-01-01

288

Family Discord, Parental Depression, and Psychopathology in Offspring: 20-Year Follow-up  

ERIC Educational Resources Information Center

Objective: To determine the independent effects of parental depression and family discord on offspring psychopathology among children at high and low risk of depression. Method: Family discord factors were assessed when subjects were approximately 17 years old, and offspring diagnoses were assessed about 20 years later. Parental and offspring…

Pilowsky, Daniel J.; Wickramaratne, Priya; Nomura, Yoko; Weissman, Myrna M.

2006-01-01

289

Over 10 years follow-up of Coats' disease in adulthood  

PubMed Central

Coats’ disease diagnosed in adulthood is rare; therefore, the treatment options and longer clinical course are not well established. We report on two cases of adult onset Coats’ disease, which have been observed for more than 10 years after conventional treatment. In the first case, a 76-year-old man with 9 years of diabetic retinopathy noticed a visual field defect in his left eye. Yellowish subretinal exudation with serous retinal detachment in his superior peripheral retina, and telangiectatic vessels with fluorescein leakage, numerous microaneurysms, and areas of capillary nonperfusion observed in a fluorescein angiography indicated adult Coats’ disease, and retinal photocoagulation was applied. Within 1 year, subretinal exudation was regressed and visual acuity was improved from 20/50 to 20/20, and was maintained for the next 11 years. In the second case, a 71-year-old man presented with decreased vision in his right eye. The fundus of his right eye showed multiple telangiectasic vessels and subretinal exudates extended to the fovea, which is diagnosed as adult Coats’ disease. Despite retinal photocoagulation, an increase of exudation and an enlargement of retinal detachment was observed within 1 month, and subsequently, additional treatment of cryotherapy was performed. Two months after these therapies, the exudation was regressed without retinal detachment, and visual acuity was improved to 20/200 which was maintained for the next 10 years. Even with adult Coats’ disease, conventional therapies of retinal photocoagulation and cryotherapy are effective and are the initial choice for improving or maintaining visual function.

Otani, Tatsuro; Yasuda, Kanako; Aizawa, Naoko; Sakai, Fumiaki; Nakazawa, Toru; Shimura, Masahiko

2011-01-01

290

Prospective study of treatment outcome of implant retained mandibular overdenture: Two years follow-up  

PubMed Central

Aims: The aim of this study is to evaluate the treatment outcome of immediately loaded Implants in the interforaminal region of anterior mandible. Materials and Methods: A total of 15 completely edentulous patients aged between 50 and 70 years were selected satisfying certain inclusion and exclusion criteria. Two implants were placed in 33 and 43 region (B and D location) and the implants were loaded immediately by mandibular overdenture retained with O-ring attachments. The implants were evaluated for various clinical parameters at 6 months, 1 year, 1.5 years, and 2 years intervals after initial placement. Results: There was increased marginal bone loss around implants during the 1st year after that the bone loss was insignificant. Clinical stability of immediately loaded implants was lower initially for 6 months, but improved by the end of 1st year. Survival rate for immediately loaded implants was 96.6% at the end of the period of study. Conclusion: Immediate loading of interforaminal mandibular implants demonstrated a highly acceptable clinical success at the end of 2 years. However, initially the marginal bone level and clinical stability were significantly lower which showed improvement with time.

Arora, Vimal; Kumar, Dinesh; Legha, V. S.; Arun Kumar, K. V.

2014-01-01

291

Blackfoot disease in Taiwan: a 30-year follow-up study  

SciTech Connect

Blackfoot disease is an endemic peripheral vascular disease found among the inhabitants of a limited area on the southwest coast of Taiwan, where artesian well water with a high concentration of arsenic has been used for more than eighty years. The natural history of blackfoot disease, based on a prospective study of 1,300 patients, is presented. The overall male/female ratio was 1.5:1. Although the clinical onset was usually insidious, it may be quite sudden and almost always begins with numbness or coldness in one or more extremities, usually the feet. Ultimately, rest pain develops and progresses to gangrene. In this series, 68% of the patients underwent spontaneous or operative amputation, and the reamputation rate was 23.3%. Lower extremity involvement in blackfoot disease was observed in 97.7% of the cases. The average annual rate for major amputation was 3.81 per 100 patient-years. The factors influencing the prognosis, such as amputation in relation to age and disease onset, are analyzed. The case fatality rate was 66.5% during thirty years; 44% of these were cardiovascular deaths. The annual death rate was 4.84 per 100 patient-years. Other reported case fatality rates for vascular insufficiency are reviewed. A dose-response relationship between blackfoot disease and the duration of water intake was also noted. The survival rates after the onset of blackfoot disease were: five years, 76.0%; ten years, 59.5%; twenty years, 38.2%; thirty years, 28.6%. The 50% survival point was 13.5 years after onset of the disease.

Tseng, W.P.

1989-06-01

292

Lung function changes in coke oven workers during 12 years of follow up  

PubMed Central

Aims: To investigate the effect of exposure to coke oven emissions on the lung function of coke oven workers. Methods: The study population, followed from 1978 and 1990, was 580 male workers with at least two sets of lung function measurements (FVC, FEV1, FEV1/FVC, and FEF25–75%). An annual rate of change (time slope) for age and height adjusted lung function index was estimated for each subject. This "time slope" was then treated as the response variable in a weighted multiple regression analysis with selected predictors. Results: For all 580 subjects, each year of working in the "operation" group (the most exposed) was found to increase the FVC decline by around 0.7 ml/year (95% CI 0.1 to 1.3 ml/year). After the exclusion of 111 subjects without detailed work history, the above finding was confirmed and each year of exposure in "operation" was also found to increase the FEV1 decline by around 0.8 ml/year (95% CI 0.1 to 1.4 ml/year). Conclusions: These findings are consistent with the results of previous cross-sectional studies. Work duration in the most exposed position in the coke ovens was associated with increased annual decline for FVC and FEV1. The estimated effect of one year of work exposure in "operation" is equivalent, in terms of the reduction in lung function, to an estimated 2.1 pack-years of smoking for FVC and 1.2 pack-years of smoking for FEV1.

Wu, J; Griffiths, D; Kreis, I; Darling, C

2004-01-01

293

Five-year follow-up of a root canal filling material in the maxillary sinus: a case report.  

PubMed

This report describes the 5-year clinical and radiographic follow-up of an accidental extrusion of a root canal filling material into the maxillary sinus and emphasizes the importance of monitoring of similar cases. The most favorable prognosis is achieved by surgically removing the extruded material from the sinus. Excess zinc oxide-eugenol-based materials in the sinus might cause aspergillosis sinusitis, and this entity often needs many years to develop. In this case, endomethasone was the filling material; however, the patient refused to undergo any surgical intervention. After a follow-up period of 5 years, the patient had no symptoms and radiographic examination disclosed no pathologic changes in the antrum. PMID:18718776

Batur, Yusuf Burak; Ersev, Handan

2008-10-01

294

Say Yes First: Follow Up of a Five-Year Rural Drug Prevention Program  

ERIC Educational Resources Information Center

"Say Yes First--To Rural Youth and Family Alcohol/Drug Prevention" (SYF) was a 5-year, federally-funded U.S.D.H.H.S. Center for Substance Abuse Prevention (CSAP) project that involved 859 children in the class of the year 2000. The children in four rural school districts were followed from Grade 4 to Grade 8 from 1991 to 1996. Initial results in a…

Zavela, Kathleen J.; Battistich, Victor; Gosselink, Carol A.; Dean, B. J.

2004-01-01

295

The Effectiveness of Drug Abuse Resistance Education (Project DARE): 5Year Follow-Up Results  

Microsoft Academic Search

Background.This article reports the results of a 5-year, longitudinal evaluation of the effectiveness of Drug Abuse Resistance Education (DARE), a school-based primary drug prevention curriculum designed for introduction during the last year of elementary education. DARE is the most widely disseminated school-based prevention curriculum in the United States.Method.Twenty-three elementary schools were randomly assigned to receive DARE and 8 were designated

Richard R. Clayton; Anne M. Cattarello; Bryan M. Johnstone

1996-01-01

296

Screen detected high blood pressure under 40: a general practice population followed up for 21 years  

Microsoft Academic Search

OBJECTIVE--To assess hypertension detected under 40 in a general practice population. DESIGN--Prospective case-control study. SETTING AND SUBJECTS--Former coal mining community in south Wales. Systematic case finding for hypertension and associated risk factors applied to a mean total population of 1945 from age 20 on a five year cycle through 21 years. Mean population aged 20-39, 227 men and 213 women.

J T Hart; C Edwards; M Hart; J Jones; M Jones; A Haines; G Watt

1993-01-01

297

Psychotic relapse and maintenance therapy in paranoid schizophrenia: a 15 year follow up  

Microsoft Academic Search

In spite of numerous reports on a 1 to 2 year maintenance neuroleptic treatment of schizophrenia, there is little systematic\\u000a information on decade-long maintenance therapy. We conducted a retrospective study in fifty outpatients with paranoid schizophrenia\\u000a who have been seen at our clinic for a duration of 15 years or more since their first psychotic episodes. Relapse rate within\\u000a 2,

Tetsuro Ohmori; Kouichi Ito; Tomohiro Abekawa; Tsukasa Koyama

1999-01-01

298

Fifteen-year follow-up for double internal thoracic artery grafts  

Microsoft Academic Search

The internal mammary artery (IMA) is the conduit of choice for myocardial revascularization. From 1972 to 1989,586 patients received bilateral IMA and supplemental vein grafts. There were 506 men (86%) and 79 women (14%) with a mean age of 55.5 years (range 32-77 years). Unstable angina was present in 138 patients (24%), insulin-requiring diabetes mellitus in 83 (14%) and previous

A. C. Fiore; K. S. Naunheim; L. R. McBride; P. S. Peigh; D. G. Pennington; G. C. Kaiser; V WILLMAN; H BARNER

1991-01-01

299

Repairing the degenerative mitral valve: Ten to fifteen-year follow-up  

Microsoft Academic Search

From January 1969 to December 1992, mitral valve reconstructive operations were performed on 155 patients with degenerative mitral valve disease. There were 102 male and 53 female patients, with a mean age of 60.5 ± 9.2 years, a mean duration of symptoms of 3.8 ± 2.7 years, and 34% were in atrial fibrillation. All patients were in New York Heart

J. M. Alvarez; C. W. Deal; K. Loveridge; P. Brennan; R. Eisenberg; M. Ward; K. Bhattacharya; S. J. Atkinson; C. Choong

1996-01-01

300

The University Experience. Eight-Year Follow-up...1966 and 1967 Freshmen.  

ERIC Educational Resources Information Center

This report is one of a series reporting data from an 11-year longitudinal study of two random samples of 100 students each, selected from the 1966 and 1967 entering freshman classes at the State University of New York at Buffalo. The study spans 10 years for each group. Responses from 60 of the 100 students in the 1966 sample and 54 of the 1967…

Hoelcle, Larene

301

Effect of antiretroviral therapy on patients' economic well being: five-year follow-up  

PubMed Central

Objective: Evaluate the effect of antiretroviral therapy (ART) on South African HIV patients’ economic well being, as indicated by symptoms, normal activities, employment, and external support, during the first 5 years on treatment. Methods: Prospective cohort study of 879 adult patients at public or nongovernmental clinics enrolled before ART initiation or on ART less than 6 months and followed for 5.5 years or less. Patients were interviewed during routine clinic visits. Outcomes were estimated using population-averaged logistic regression and reported as proportions of the cohort experiencing outcomes by duration on ART. Results: For patients remaining in care, outcomes improved continuously and substantially, with all differences between baseline and 5 years statistically significant (P?year 3 and year 5. The probability of reporting pain last week fell from 69% during the three months before starting ART to 17% after 5 years on ART and fatigue from 62 to 7%. The probability of not being able to perform normal activities in the previous week fell from 47 to 5% and of being employed increased from 32 to 44%; difficulty with job performance among those employed fell from 56 to 6%. As health improved, the probability of relying on a caretaker declined from 81 to less than 1%, and receipt of a disability grant, which initially increased, fell slightly over time on ART. Conclusion: Results from one of the longest prospective cohorts tracking economic outcomes of HIV treatment in Africa suggest continuous improvement during the first 5 years on treatment, confirming the sustained economic benefits of providing large-scale treatment.

Rosen, Sydney; Larson, Bruce; Rohr, Julia; Sanne, Ian; Mongwenyana, Constance; Brennan, Alana T.; Galarraga, Omar

2014-01-01

302

[Cubital tunnel syndrome: a retrospective review of 55 subcutaneous transpositions with minimum 3-year follow-up].  

PubMed

The surgical management of the cubital tunnel syndrome has no strict rules to follow. Surgical treatments are various, but none of them has been shown to be superior to the others. This retrospective study presents the clinical results in 73 patients who underwent an anterior subcutaneous transposition of the ulnar nerve, between January 2000 and January 2010, with a minimum 3-year follow-up. Fifty-five patients were assessed with an average follow-up of 65.7 months. McGowan grading system as modified by Goldberg was used to analyse clinical results, preoperatively and at follow-up. The DASH score was used to assess physical function. The average preoperative evolution of symptoms was 16.7 months, and mean period to resolution was 4.7 months. The grade in McGowan grading system as modified by Goldberg significatively improved at follow-up (P=0.0002). Only five patients kept paresthesia. The mean postoperative DASH score was 7.27/100. The satisfaction rate was 96%, and all the patients except one returned back to their occupation. There was neither infection nor complex regional pain syndrome. The anterior subcutaneous transposition leads to very good clinical results, satisfaction and physical function. It is an effective surgical method, without complication in our study, which gives long-term results. PMID:24029141

Guinet, V; Cordier-Fuzeau, C; Auquit-Auckbur, I

2013-10-01

303

Magnetic resonance imaging, radiography, and scintigraphy of the finger joints: one year follow up of patients with early arthritis  

PubMed Central

OBJECTIVES—To evaluate synovial membrane hypertrophy, tenosynovitis, and erosion development of the 2nd to 5th metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints by magnetic resonance imaging in a group of patients with rheumatoid arthritis (RA) or suspected RA followed up for one year. Additionally, to compare the results with radiography, bone scintigraphy, and clinical findings.?PATIENTS AND METHODS—Fifty five patients were examined at baseline, of whom 34 were followed up for one year. Twenty one patients already fulfilled the American College of Rheumatology (ACR) criteria for RA at baseline, five fulfilled the criteria only after one year's follow up, whereas eight maintained the original diagnosis of early unclassified polyarthritis. The following MRI variables were assessed at baseline and one year: synovial membrane hypertrophy score, number of erosions, and tenosynovitis score.?RESULTS—MRI detected progression of erosions earlier and more often than did radiography of the same joints; at baseline the MRI to radiography ratio was 28:4. Erosions were exclusively found in patients with RA at baseline or fulfilling the ACR criteria at one year. At one year follow up, scores of MR synovial membrane hypertrophy, tenosynovitis, and scintigraphic tracer accumulation had not changed significantly from baseline; in contrast, swollen and tender joint counts had declined significantly (p<0.05).?CONCLUSIONS—MRI detected more erosions than radiography. MR synovial membrane hypertrophy and scintigraphy scores did not parallel the changes seen over time in clinically assessed swollen and tender joint counts. Although joint disease activity may be assessed as quiescent by conventional clinical methods, a more detailed evaluation by MRI may show that a pathological condition is still present within the synovium.??

Klarlund, M; Ostergaard, M; Jensen, K; Madsen, J; Skjodt, H; Lorenzen, I; the, T

2000-01-01

304

[The Marburg Parent-Child Spelling Trainer--follow up studies after 2 years].  

PubMed

The results of a two-year parent-child training program are reported. After one year of supervised tutoring by one of their parents, the children had only improved in those spelling areas that had been worked on in the program, otherwise there was no general improvement in their spelling ability. After the second year, not only their spelling ability in the specific areas had continued to increase, but their general spelling ability (spelling test percentile rank) had also improved. Their self-confidence had increased markedly as well. Significant predictors of the specific spelling improvement were the specific spelling ability at the initial measurement and whether or not the mother was working; significant predictors for the general improvement could not be found. Supervised tutoring by the parents was shown to be effective for improving childrens' spelling ability. PMID:9757528

Schulte-Körne, G; Deimel, W; Remschmidt, H

1998-08-01

305

Treatment of EBV driven lymphoproliferation with erythrophagocytosis: 12 year follow up  

PubMed Central

This is a report of a case of Epstein-Barr virus (EBV) associated haemophagocytic syndrome in a 17 year old woman with antibody deficiency. For two years before this presentation, serology showed abnormally high titres to EBV early antigen, suggestive of persistent infection with EBV. She became acutely unwell with clinical features consistent with virus associated haemophagocytic syndrome (VAHS). Histology showed lymphoproliferation with erythrophagocytosis and evidence of EBV encoded RNAs in liver, spleen, and lymph node. VAHS is often fatal, particularly when it occurs in patients with underlying immunodeficiencies. In this case, treatment with intravenous immunoglobulin, aciclovir, and ? interferon was followed by a dramatic recovery. Twelve years later the patient remains relatively well on regular intravenous immunoglobulin. Key Words: Epstein-Barr virus associated haemophagocytic syndrome • antibody deficiency • ? interferon

Bethune, C; Gompels, M; Taylor, C; Angus, B; Spickett, G

2001-01-01

306

Mortality rate after open Roux-in-Y gastric bypass: a 10-year follow-up.  

PubMed

The prevalence of obesity has increased to epidemic status worldwide. Thousands of morbidly obese individuals undergo bariatric surgery for sustained weight loss; however, mid- and long-term outcomes of this surgery are still uncertain. Our objective was to estimate the 10-year mortality rate, and determine risk factors associated with death in young morbidly obese adults who underwent bariatric surgery. All patients who underwent open Roux-in-Y gastric bypass surgery between 2001 and 2010, covered by an insurance company, were analyzed to determine possible associations between risk factors present at the time of surgery and deaths related and unrelated to the surgery. Among the 4344 patients included in the study, 79% were female with a median age of 34.9 years and median body mass index (BMI) of 42 kg/m2. The 30-day and 10-year mortality rates were 0.55 and 3.34%, respectively, and 53.7% of deaths were related to early or late complications following bariatric surgery. Among these, 42.7% of the deaths were due to sepsis and 24.3% to cardiovascular complications. Male gender, age ?50 years, BMI ?50 kg/m2, and hypertension significantly increased the hazard for all deaths (P<0.001). Age ?50 years, BMI ?50 kg/m2, and surgeon inexperience elevated the hazard of death from causes related to surgery. Male gender and age ?50 years were the factors associated with increased mortality from death not related to surgery. The overall risk of death after bariatric surgery was quite low, and half of the deaths were related to the surgery. Older patients and superobese patients were at greater risk of surgery-related deaths, as were patients operated on by less experienced surgeons. PMID:24919174

Bruschi Kelles, S M; Diniz, M F H S; Machado, C J; Barreto, S M

2014-07-01

307

Giant coronary pseudoaneurysm. Five-year follow-up after bypass grafting.  

PubMed

A roentgenogram of the shoulder in a 25-year-old man with an athletic injury revealed a large mass along the left heart border. Evaluation with coronary arteriography established the diagnosis of a massive aneurysm of the left anterior descending coronary artery. The aneurysm was excised and a saphenous vein bypass graft was placed into the distal artery. Histologic examination revealed that the excised segment was a false aneurysm. Five years postoperatively, the patient is asymptomatic and the graft remains widely patent. PMID:6969827

Chun, P K; Davia, J E; Cheitlin, M D; Green, D C; Bowen, T E; Brott, W H

1981-01-01

308

Reestablishment of esthetics with minimum thickness veneers: a one-year follow-up case report.  

PubMed

The evolution of adhesive procedures and ceramic systems has allowed for the placement of minimum thickness laminate veneers on unprepared teeth. A 20-year-old post-orthodontics male patient with multiple diastemas required restorative procedures. A multidisciplinary approach was performed, involving gingivectomy, in-office bleaching, and application of minimum thickness veneers. The immediate and 1-year followup results exceeded expectations; however, long-term clinical trials are necessary to evaluate the performance of this new type of indirect restoration. PMID:24847498

Alencar, Marina Studart; Araújo, Diana Ferreira; Maenosono, Rafael Massunari; Ishikiriama, Bella Luna; Francischone, Carlos Eduardo; Ishikiriama, Sérgio Kiyoshi

2014-01-01

309

The Longitudinal Assessment Study (LAS): Eighteen Year Follow-Up. Final Report.  

ERIC Educational Resources Information Center

Premised on the view that students with more years of Montessori education (MEY) would possess to a higher degree those qualities emphasized in the Montessori environment and that Montessori students would be as successful as students more traditionally educated, this report presents the final assessment for the Longitudinal Assessment Study,…

Glenn, Christopher M.

310

Implications of Japan's Center-Based Night Care: A 1-Year Follow-up  

ERIC Educational Resources Information Center

With increasing numbers of women joining the evening/nighttime workforce, there is a need for quality childcare during these hours. This project, conducted in Japan, sought to compare the effects of expanded childcare on the development and adaptation of 866 young children after one year. Parents completed a survey on the childrearing environment…

Anme, Tokie; Segal, Uma A.

2007-01-01

311

The Stability and Structure of Career Decision-Making Profiles: A 1-Year Follow-Up  

ERIC Educational Resources Information Center

The Career Decision-Making Profile (CDMP) questionnaire is a multidimensional measure of the way individuals make career decisions, developed as an alternative to the single, most-dominant trait approach. Using a sample of freshmen students, the 2-week reliability (N = 273) and 1-year stability (N = 182) of the CDMP was tested for each of the 12…

Gati, Itamar; Levin, Nimrod

2012-01-01

312

Assertive Community Treatment (ACT) in Singapore: A 1-year Follow-up Study  

Microsoft Academic Search

Introduction: Assertive Community Treatment (ACT) provides community-based treatment to patients with severe and persistent psychiatric illnesses, so that they may continue to live and function in the community as they receive psychiatric care. This study aimed to examine the effects of ACT on the outcome of patients over a 1-year period in an Asian population. Materials and Methods: This naturalistic

Johnson Fam; Cheng Lee; Boon-Leng Lim; Kiang-Kim Lee

2007-01-01

313

Suicidal thoughts and attempts among adolescents: a longitudinal 8-year follow-up study  

Microsoft Academic Search

Background: To study the prevalence of and factors associated with suicidal behaviour among 580 adolescents. Methods: An 8-year longitudinal study included questions about suicidal attempts and thoughts at age 16. Children were evaluated with parent and teacher Rutter scales and self-reported Child Depression Inventory at age 8. At age 16, parents filled in the Child Behaviour Check List and adolescents

Andre Sourander; Leila Helstelä; Antti Haavisto; Lasse Bergroth

2001-01-01

314

Fifteen Year Follow-Up Geography Skills Test Administered in Indiana, 1987 and 2002  

ERIC Educational Resources Information Center

After fifteen years of geographic education efforts, a baseline geography skills test was repeated in Indiana. In 2002, 2,278 students in college freshman geography courses were tested with a revision of the National Council for Geographic Education Competency-Based Geography Test, Secondary Level Form II. The test measured geographic ability in…

Bein, F. L.; Hayes, James J.; Jones, Thomas G.

2009-01-01

315

Changing Network Support for Drinking: Network Support Project 2-Year Follow-up  

ERIC Educational Resources Information Center

The Network Support Project was designed to determine whether a treatment could lead patients to change their social network from one that supports drinking to one that supports sobriety. This study reports 2-year posttreatment outcomes. Alcohol-dependent men and women (N = 210) were randomly assigned to 1 of 3 outpatient treatment conditions:…

Litt, Mark D.; Kadden, Ronald M.; Kabela-Cormier, Elise; Petry, Nancy M.

2009-01-01

316

Disability in young adults following major trauma: 5 year follow up of survivors  

Microsoft Academic Search

BACKGROUND: Injuries are a major cause of mortality and morbidity in young people. Despite this, the long-term consequences for young survivors of severe injury are relatively unexplored. METHODS: Population based cohort study involving 5 year post injury structured interview of all cases of major trauma (Injury Severity Score > 15) identified retrospectively for 12 month period (1988 to 1989) within

Sian A Evans; Mark C Airey; Susan M Chell; James B Connelly; Alan S Rigby; Alan Tennant

2003-01-01

317

Substance use and abuse among adolescent runaways: A four-year follow-up study  

Microsoft Academic Search

Using data from the National Longitudinal Study Youth Survey (NLSY), runaway status in early adolescence (ages 14–15) was associated with subsequent (four years later) substance abuse, alcohol problems, and school dropout status. Three runaway categories were formed—never runaway, runaway once, and runaway two or more times. Overall, the repeat runaways reported engaging in higher levels of substance use and abuse

Michael Windle

1988-01-01

318

Vascular Risk Factors and Dementia: 40Year Follow-Up of a Population-Based Cohort  

Microsoft Academic Search

Aims: Our aim was to evaluate the longitudinal associations of individual and multiple vascular risk factors with the subsequent development of dementia and Alzheimer’s disease (AD). Methods: The Uppsala Longitudinal Study of Adult Men started in 1970 when the 2,268 participants were 50 years old. Baseline investigations included determinations of blood pressure, fasting glucose, cholesterol, BMI and smoking status. Over

Elina Rönnemaa; Björn Zethelius; Lars Lannfelt; Lena Kilander

2011-01-01

319

Families' Goals, School Involvement, and Children's Academic Achievement: A Follow-Up Study Thirteen Years Later  

ERIC Educational Resources Information Center

A study conducted from 1996-2000 focused on the academic development of children within a statewide educational reform effort, including changing the organizational structure of the early years of schooling into nongraded primary programs (formerly age-based classrooms for kindergarteners through third grade). The multisite study involved children…

Kyle, Diane W.

2011-01-01

320

A Content Analysis of School Anti-Bullying Policies: A Follow-Up after Six Years  

ERIC Educational Resources Information Center

An analysis was undertaken of 217 English school anti-bullying policies, from 169 primary schools and 48 secondary schools, using a 34-item scoring scheme. Findings were compared with an analysis of 142 schools six years earlier. Overall schools in the current analysis had about 49% of the items in their policies, a modest increase over the…

Smith, Peter K.; Kupferberg, Allison; Mora-Merchan, Joaquin A.; Samara, Muthanna; Bosley, Sue; Osborn, Rob

2012-01-01

321

Clinical evaluation of two packable posterior composites: 2-year follow-up.  

PubMed

The clinical performance of two packable posterior composites, Alert (A)-Jeneric/Pentron and SureFil (S)-Dentsply, was evaluated in 33 patients. Each patient received one A and one S restoration, resulting in a total of 66 restorations. The restorations were placed by one operator according to the manufacturer's specifications and were finished and polished after 1 week. Photographs were taken at baseline and after 2 years. Two independent evaluators conducted the clinical evaluation by using modified United States Public Health Service criteria. After 2 years, 60 restorations (30 A and 30 S), 27 class I (16 A and 11 S) and 33 class II (14 A and 19 S) were evaluated in 30 patients. Criterion A for recurrent caries, vitality, and retention was applicable to all 60 restorations. Criterion B was distributed among 40 restorations as follows: surface texture (15 A; 2 S), color (5 A; 6 S), postoperative sensitivity (1 S), marginal discoloration (8 A), marginal adaptation (3 A), and wear resistance (2 A). Data were analyzed using the Exact Fisher and McNemar tests. After 2 years, S showed a significantly better performance than A with respect to surface texture and marginal discoloration. The clinical performance of both materials was considered acceptable over the 2-year period. Further evaluations are necessary for a more in-depth analysis. PMID:16823554

Fagundes, T C; Barata, T J E; Bresciani, E; Cefaly, D F G; Jorge, M F F; Navarro, M F L

2006-09-01

322

Follow-Up Study of Students Completing Selected Occupational Programs in Fiscal Year 1990.  

ERIC Educational Resources Information Center

In March 1991, 3,081 fiscal year 1990 graduates of selected occupational programs in the Illinois Community College System (ICCS) were surveyed concerning their objectives for attending college, current educational status, present employment status, salary, employment start-up, geographic location of employment, and satisfaction with their…

Illinois Community Coll. Board, Springfield.

323

Treating Sexually Abused Children: 1 Year Follow-Up of a Randomized Controlled Trial  

ERIC Educational Resources Information Center

Objective:: To measure the durability of improvement in response to two alternative treatments for sexually abused children. Method:: Eighty-two sexually abused children ages 8-15 years old and their primary caretakers were randomly assigned to trauma-focused cognitive-behavioral therapy (TF-CBT) or non-directive supportive therapy (NST) delivered…

Cohen, J.A.; Mannarino, A.P.; Knudsen, K.

2005-01-01

324

Paraneoplastic cerebellar degeneration associated with multiple myeloma —3.4 years follow up  

Microsoft Academic Search

A 57 year old female patient demonstrated subacute generalized cerebellar symptoms and the investigations which were done exhibited that the clinical picture was due to the remote effect of multiple myeloma. In this case of paraneoplastic cerebellar degeneration, MRI showed cerebellar vermian atrophy when the brain CT scan was negative.

Sevket Akpinar; Önder Berk; Levent Karaca

1990-01-01

325

Pubertal Timing and Substance Use in Middle Adolescence: A 2-Year Follow-Up Study  

ERIC Educational Resources Information Center

Earlier research has associated early puberty with emotional and behavioral symptoms particularly among girls, while among boys, findings have been contradictory as to whether risks are associated with early or late pubertal timing. We studied the association between pubertal timing and substance use behaviors in middle adolescence in a 2-year

Kaltiala-Heino, Riittakerttu; Koivisto, Anna-Maija; Marttunen, Mauri; Frojd, Sari

2011-01-01

326

Who Leaves and Who Stays in Special Education: A 2-Year Follow-up Study.  

ERIC Educational Resources Information Center

A two-year study assessing the stability of 1,184 elementary special education students found 71 percent stayed in special education with the same classification, 12 percent remained with a different classification, and 17 percent were no longer in special education. The original primary classification was the best predictor of reclassification…

Walker, Deborah K.; And Others

1988-01-01

327

Educational Goal Attainment: A One-Year Follow-Up Study of Nonreturning JCCC Students.  

ERIC Educational Resources Information Center

Each year since 1989, Johnson County Community College (JCCC) (Kansas) has conducted studies on student leavers-- students who have left the community college without graduating, who transferred to other institutions, or who have gained skills through career programs. The most recent study was conducted through mailings to students, of which 699…

Conklin, Karen A.

328

Children of Methadone-Maintained Mothers: Three-Year Follow-Up.  

ERIC Educational Resources Information Center

The physical and neurobehavioral findings at 3 years of age for 39 children born to mothers on methadone- maintenance and 23 children born to drug-free comparison mothers are reported. The methadone children had a higher incidence of head circumferences less than the third percentile, nystagmus/strabismus, and otitis media. No differences were…

Johnson, Helen L.; And Others

329

A 7-Year Longitudinal Follow-Up of Intellectual Development in Children with Congenital Hemiplegia  

ERIC Educational Resources Information Center

Aims: Our aim was to examine intellectual development in children with congenital hemiplegia from early childhood to adolescence. Method: Full-scale IQ (FIQ), Verbal IQ (VIQ), and Performance IQ (PIQ) scores were measured in 32 participants (19 males, 13 females) with congenital hemiplegia at mean ages of 4 years 6 months (SD 7mo; 31…

Gonzalez-Monge, Sibylle; Boudia, Baya; Ritz, Annie; Abbas-Chorfa, Fatima; Rabilloud, Muriel; Iwaz, Jean; Berard, Carole

2009-01-01

330

A Program To Promote Positive Body Image: A 1-Year Follow-Up Evaluation.  

ERIC Educational Resources Information Center

Evaluated the effectiveness of a program designed to promote body image satisfaction and prevent eating problems in young adolescent girls over a 1-year period. Found no program effect. Found instead, significant increases in body image satisfaction and decreases in eating problem scores over time for participants in both the prevention and…

McVey, Gail L.; Davis, Ron

2002-01-01

331

Teachers' Reflections of Cooperative Learning (CL): A Two-Year Follow-Up  

ERIC Educational Resources Information Center

Although teachers often report that they subscribe to cooperative learning (CL) to help students attain social and academic goals, research indicates that they often have difficulties implementing and sustaining their commitment. The purpose of this study is to report on the reflections of seven middle-year teachers who had embedded CL in their…

Gillies, Robyn M.; Boyle, Michael

2011-01-01

332

A Seven-Year Follow-Up of Intelligence Test Scores of Foster Grandparents  

ERIC Educational Resources Information Center

After seven years, a group (N=32) of originally nonemployed poverty-level older people (over 60) now employed as foster grandparents were retested with the WAIS. Three subtest scores showed stability and Digit Span showed a statistically significant drop. Neither age nor initial level of health or WAIS scores was related to test-score changes over…

Troll, Lillian E.; And Others

1976-01-01

333

Three Year Follow-Up Report on Training Standardization and Utilization of Family Planning Nurse Practitioners.  

National Technical Information Service (NTIS)

Training and utilization of family planning nurse practitioners has received a high priority in the eight southeastern States for the past 3 years. Region-wide standards for training have been developed and applied by the five region-based training progra...

R. H. Richardson A. Earles B. Melton P. Fabel

1975-01-01

334

The Five-Year Follow-Up Report: A Survey of 1986-1987 Graduates.  

ERIC Educational Resources Information Center

In 1992, a survey was conducted of students who had graduated from the five colleges of the Arrowhead Community College Region (ACCR) during the 1986-87 academic year. Surveys were mailed to all 785 graduates, requesting information on their educational backgrounds, current employment, and assessment of their educational experience. Responses were…

Arrowhead Community Coll. Region, Grand Rapids, MN.

335

Some Effects of Schooling: A Three Year Follow-Up of a Title III Project.  

ERIC Educational Resources Information Center

This paper presents an evaluation of a 3-year Title III project carried out in the Vigo County School Cooperation, Terre Haute, Indiana. The project involved the evaluation of three differing instructional methodologies utilized in three elementary schools which also differed in the socioeconomic background of the students. The Dixie Bee school,…

Barclay, James R.; And Others

336

Psychopathology in a Large Cohort of Sexually Abused Children Followed up to 43 Years  

ERIC Educational Resources Information Center

Objective: To determine the rate and risk of clinical and personality disorders diagnosed in childhood and adulthood in those known to have been sexually abused during childhood. Methods: Forensic medical records of 2,759 sexually abused children assessed between 1964 and 1995 were linked with a public psychiatric database between 12 and 43 years

Cutajar, Margaret C.; Mullen, Paul E.; Ogloff, James R. P.; Thomas, Stuart D.; Wells, David L.; Spataro, Josie

2010-01-01

337

Development of aerobic and anaerobic power in adolescent rowers: a 5-year follow-up study.  

PubMed

We aimed to determine whether the physical and physiological superiority of early-maturing rowing athletes, observed at ages 12-13 years, over that of their late-maturing counterparts observed at the same ages, still persists at 17-18 years of age, when all adolescent athletes are expected to have completed pubertal development. We hypothesized that this superiority of early maturers would not be observed at reassessment, as late maturers would have likely "caught up" with their early-maturing peers. Twenty-one male rowers were assessed at age 12.8 ± 0.5 years and again at 17.5 ± 0.5 years (mean ± SD). They were divided into groups of early-maturing and late-maturing rowing athletes based on Tanner's sexual maturity ratings. A two-way repeated-measures MANOVA followed by a series of ANOVAs with one within-subject factor (time) and one between-subject factor (group) indicated significant (P?0.003) within-subject and between-subjects main effects for lean body mass (LBM), maximal oxygen uptake (VO2max), and mean power (MP). The group × time interaction effects were significant for LBM (P=0.003), VO2max (P=0.004), but not for MP (P=0.171). Over 5 years, early-maturers' advantage dwindled in terms of LBM (+38% to +9%), VO2max (+47% to +9%), and MP (+76% to +15%); however, these differences may still be considered practically relevant. The proposed hypothesis was not supported. PMID:20807382

Mikulic, P

2011-12-01

338

A mild decrease of renal function is related to increased hemoglobin level during 5-year follow-up period  

PubMed Central

Background/Aims We analyzed chronological changes in hemoglobin according to renal function changes over a 5-year follow-up period. Methods We enrolled 5,266 adults with a glomerular filtration rate (GFR) ? 60 mL/min/1.73 m2 at an initial examination at a routine health check-up; a follow-up examination was conducted 5 years later. We categorized the subjects according to GFR ratio (groups 1, 2, and 3, defined as GFRratio ? 1.00, 0.75 to 0.99, and < 0.75, respectively). Results The mean hemoglobin level in subjects with a GFR of 60 to 74 was higher than in those with a GFR of 75 to 89 or ? 90 mL/min/1.73 m2 at the initial examination (all p < 0.001). Among females and males, the frequencies of increased hemoglobin were 46.8% and 40.6% in the GFRratio group 1, 52.4% and 46.1% in group 2, and 59.6% and 52.5% in group 3 over the 5-year period, respectively (all p < 0.001). With multiple logistic regression, group 3 showed 1.594-fold (95% confidence interval [CI], 1.127 to 2.225) and 1.353-fold (95% CI, 1.000 to 1.830) higher likelihoods of increased hemoglobin over the 5-year follow-up period in females and males, respectively. The estimated difference in hemoglobin level was highest in group 3 in both genders. These findings were more evident in subgroups without metabolic syndrome, diabetes mellitus, hypertension, or GFR less than 90 mL/min/1.73 m2. Conclusions Among a population with GFR ? 60 mL/min/1.73 m2, a mild decrease in GFR over a 5-year follow-up period was associated with an increase in hemoglobin levels.

Shin, Nara; Kim, Hyunsuk; Kim, Hyo Jin; Han, Miyeun; Lee, Sunhwa; Jo, Hyungah; Hyuk, Huh

2014-01-01

339

Patient initiated outpatient follow up in rheumatoid arthritis: six year randomised controlled trial  

PubMed Central

Objectives To determine whether direct access to hospital review initiated by patients with rheumatoid arthritis would result in improved clinical and psychological outcome, reduced overall use of healthcare resources, and greater satisfaction with care than seen in patients receiving regular review initiated by a rheumatologist. Design Two year randomised controlled trial extended to six years. Setting Rheumatology outpatient department in teaching hospital. Participants 209 consecutive patients with rheumatoid arthritis for over two years; 68 (65%) in the direct access group and 52 (50%) in the control group completed the study (P = 0.04). Main outcome measures Clinical outcome: pain, disease activity, early morning stiffness, inflammatory indices, disability, grip strength, range of movement in joints, and bone erosion. Psychological status: anxiety, depression, helplessness, self efficacy, satisfaction, and confidence in the system. Number of visits to hospital physician and general practitioner for arthritis. Results Participants were well matched at baseline. After six years there was only one significant difference between the two groups for the 14 clinical outcomes measured (deterioration in range of movement in elbow was less in direct access patients). There were no significant differences between groups for median change in psychological status. Satisfaction and confidence in the system were significantly higher in the direct access group at two, four, and six years: confidence 9.8 v 8.4, 9.4 v 8.0, 8.7 v 6.9; satisfaction 9.3 v 8.3, 9.3 v 7.7, 8.9 v 7.1 (all P < 0.02). Patients in the direct access group had 38% fewer hospital appointments (median 8 v 13, P < 0.0001). Conclusions Over six years, patients with rheumatoid arthritis who initiated their reviews through direct access were clinically and psychologically at least as well as patients having traditional reviews initiated by a physician. They requested fewer appointments, found direct access more acceptable, and had more than a third fewer medical appointments. This radical responsive management could be tested in other chronic diseases.

Hewlett, Sarah; Kirwan, John; Pollock, Jon; Mitchell, Kathryn; Hehir, Maggie; Blair, Peter S; Memel, David; Perry, Mark G

2005-01-01

340

Five Year Follow-Up Comparing Tension-Free Vaginal Tape and Colposuspension  

PubMed Central

Burch colposuspension has been the procedure of choice for stress urinary incontinence, more recently the tension-free vaginal tape (TVT) has been used. A retrospective study on all TVT's and colposupensions was performed. The present clinical condition was assessed using the Bristol Female Lower Urinary Tract Symptoms and Short-Form 12 questionnaires. The median operating time was 50-59 minutes for TVT and 70-79 minutes for colposupension. The median number of day's hospitalization was 3 and 10 respectively. The overall success rate was 88.5% and 92% respectively. No significant difference in subjective outcome was noted at more than 5 years after surgery between the two procedures for either the BFLUTS or SF-12. The initial surgical success for TVT surgery is maintained over a period greater than five years.

McCracken, Geoff R; Henderson, Nicola A; Ashe, Robin G

2007-01-01

341

Nephropathic cystinosis associated with cardiomyopathy: A 27-year clinical follow-up  

PubMed Central

Background Nephropathic cystinosis is an autosomal recessive disease resulting from intracellular accumulation of cystine leading to multiple organ failure. Case report We describe the clinical course of a patient managed from the age of six until his death at the age of 33 years. He underwent multiple surgery, including two renal transplants, developed transplant renal artery stenosis that was managed medically, and progressive heart failure at the age of 33 years. His death from a ruptured pseudoaneurysm associated with a restrictive cardiomyopathy is noteworthy. A limited cardiac autopsy revealed the presence of cystine crystals in interstitial cardiac histiocytes and one myocardial cell, along with 1000-fold higher tissue cystine content of the left ventricular myocardium compared to patients without cystinosis, suggesting the possibility of direct cystine mediated metabolic injury.

Dixit, Mehul P; Greifer, Ira

2002-01-01

342

Multiple glomuvenous malformations presenting in a child: follow-up over a period of 8 years.  

PubMed

Multiple glomuvenous malformations (GVMs) are a rare condition which usually present in children with only a handful of cases reported in the literature. It is usually congenital and has an autosomal dominant inheritance pattern. They may be distributed throughout the body in either a localised, segmental or disseminated pattern. Pain, which is a characteristic feature of glomus tumours, is less often associated with GVMs. In addition, unlike glomus tumours which most commonly occur over acral skin surfaces, GVMs may occur throughout the body. A number of treatment options are available including surgical excision, laser treatments and sclerotherapy. We present the case of a 14-year-old boy with multiple GVMs which were treated with surgical excision and followed him up over a period of 8 years. PMID:23853196

Jabir, Shehab; Frew, Quentin; Petkar, Mahir; Dziewulski, Peter

2013-01-01

343

Eight year follow-up dental treatment in a patient with Treacher Collins syndrome.  

PubMed

Treacher Collins syndrome (TCS) is an autosomal dominant disorder of craniofacial development characterized by variable involvement of the craniofacial structures derived from the first and second branchial arches. Occurrence of this syndrome is relatively rare with wide variations in the clinical expression. Aspects of speech, appearance, and social well-being along with psychological issues are hampered in these patients. Treating such disabled children poses a great challenge not only in the medical field but also in the dental meadow. We report a case of a 5-year-old boy who presented with this syndrome and the dental treatment was carried out with a noteworthy outcome for a period of 8 years. A brief review of etiology, dental anomalies along with prognosis is documented. PMID:23263431

Ranadheer, E; Nagaraju, K; Suresh, P; Updesh, M

2012-01-01

344

Young adult outcome of attention deficit hyperactivity disorder: a controlled 10-year follow-up study  

Microsoft Academic Search

Background. Our objective was to estimate the lifetime prevalence of psychopathology in a sample of youth with and without attention deficit hyperactivity disorder (ADHD) through young adult- hood using contemporaneous diagnostic and analytic techniques. Method. We conducted a case-control, 10-year prospective study of ADHD youth. At baseline, we assessed consecutively referred male, Caucasian children with (n=140) and without (n=120) DSM-

JOSEPH BIEDERMAN; MICHAEL C. MONUTEAUX; ERIC MICK; THOMAS SPENCER; TIMOTHY E. WILENS; JULIE M. SILVA; LINDSEY E. SNYDER; STEPHEN V. FARAONE

2006-01-01

345

Mortality among US underground coal miners: A 23-year follow-up  

Microsoft Academic Search

The mortality experience over 22-24 years of 8,899 working coal miners initially medically examined in 1969-1971 at 31 U.S. coal mines was evaluated. A cohort life-table analysis was undertaken on underlying causes of death, and proportional hazards models were fitted to both underlying, and underlying and contributing causes of death. Elevated mortality from nonviolent causes, nonmalignant respiratory disease (NMRD), and

M. D. Attfield; E. D. Kuempel

2008-01-01

346

Flow cytometry of colorectal carcinoma with three-year follow-up  

Microsoft Academic Search

Flow cytometry DNA measurements were carried out on colorectal carcinomas from a series of 33 patients who have since been\\u000a followed for three to four years. The tumors could be subclassified by this technique into 15 that had near-diploid DNA and\\u000a 18 that were aneuploid. Prior reports had suggested that the near-diploid tumors carry a better prognosis than aneuploid tumors,

Myron R. Melamed; Warren E. Enker; Perry Banner; Abbe J. Janov; Glen Kessler; Zbigniew Darzynkiewicz

1986-01-01

347

A 12-year follow-up study of treated obese children in Japan  

Microsoft Academic Search

Objective: To assess tracking for body weight from childhood to adulthood in obese Japanese children who were treated for obesity, investigate the relation between the changes in body weight status and morbidity, and identify correlates of the changes in body weight status.Study Design: Twelve-year retrospective cohort study.Subjects: A sample of 276 subjects (age 23.9±4.1, 176 males and 100 females) who

K Togashi; H Masuda; T Rankinen; S Tanaka; C Bouchard; H Kamiya

2002-01-01

348

A Two-Year-Old with Rickets: Diet History, Treatment and Follow-Up  

Microsoft Academic Search

AJ, a 2-year-old African-American male, was referred to a nutrition and gastroenterology clinic with the diagnosis of rickets and iron deficiency anemia, both of which were secondary to poor nutrition. All of the classic signs of rickets were present: frontal bossing, rachitic rosary, enlarged joints, and bowed legs with the latter condition making it impossible for AJ to walk without

K. R. Kramer; S. M. Phillips; J. Radcliffe

1998-01-01

349

Gastric Bypass and Vertical Banded Gastroplasty a Prospective Randomized Comparison and 5Year Follow-up  

Microsoft Academic Search

Background: a prospective randomized study was undertaken to compare the outcome of vertical banded gastroplasty (VBG) and\\u000a gastric bypass (GBP) in patients with clinically severe obesity. Methods: eligibility criteria included Class IV obesity,\\u000a <50 years old and a history of at least one attempt of non-operative weight loss. Patients were managed conservatively for\\u000a 3 months prior to surgery. Patients were

Lyn Howard; Margaret Malone; Ann Michalek; John Carter; Sharon Alger; Joanne Van Woert

1995-01-01

350

Mortality attributable to cigarette smoking in Taiwan: a 12-year follow-up study  

Microsoft Academic Search

BACKGROUNDAssessment of the impact of cigarette smoking on mortality helps to indicate the importance of tobacco control in a given country.OBJECTIVESTo examine the relative risk of dying from various diseases for cigarette smoking and to estimate annual mortality attributable to cigarette smoking in Taiwan.DESIGNProspective cohort study.SUBJECTS AND SETTINGA cohort of 14 397 male and female residents aged 40 years or

Kuo-Meng Liaw; Chien-Jen Chen

1998-01-01

351

Effectiveness of Japan's extended\\/night child care: A five-year follow up  

Microsoft Academic Search

Background: With increasing numbers of women joining the evening\\/nighttime and extended-hour workforce, there is a need for quality childcare during these hours.Methods: This project, conducted in Japan, sought to compare the effects of expanded child-care on the development and adaptation of 185 young children after five years in care. Parents completed a survey on the childrearing environment at home, their

T. Anme; H. Tanaka; R. Shinohara; Y. Sugisawa; E. Tanaka; L. Tong; T. Watanabe; Y. Onda; Y. Kawashima; E. Tomisaki; H. Mochizuki; M. Hirano; K. Morita; A. Gan-Yadam; Uma Segal

2010-01-01

352

Vitrectomy and fluid\\/silicone-oil exchange for giant retinal tears: 5 years follow-up  

Microsoft Academic Search

A series of 64 eyes, in 64 patients with giant retinal tears, treated by vitrectomy and fluid\\/silicone-oil exchange, has been reviewed after 5 years. Anatomical success was achieved in 73% of cases and visual function in successful cases ranged from 6\\/6 to NPL; 66% achieved acuities of 6\\/60 or better and 32% had vision of 6\\/18 or better. These results

Peter K. Leaver; Brenda M. Billington

1989-01-01

353

Allergy from infancy to adolescence. A population-based 18-year follow-up cohort  

PubMed Central

Background Anxious parents have many concerns about the future health of their atopic infants. Paediatricians and primary care practitioners need to seek knowledge on long-term outcomes in order to cope with the increasing caseload of suspected allergy and the concerns of parents. The aim of the study was to assess suspected and diagnosed allergy in infancy as predictors of allergy and asthma in adolescence. Methods Families expecting their first baby and making their first visit to a maternity health care clinic in 1986 were selected as the study population in a random sample. There were 1278 eligible study families. The data were provided of the children at the ages of 9 and 18 months and 3, 5, 12, 15 and 18 years by health care professionals, parents, and adolescents (themselves). Results At the age of 9 months, the prevalence of allergy suspicions was distinctly higher than that of allergy diagnoses. At the age of five years suspected allergy approaches were nil, and the prevalence of diagnosed allergy was about 9%. During the adolescence, the prevalence of self-reported allergy increases steadily up to the age of 18 years, and that of asthma remains at approximately 5%. Suspected allergy at the age of 9 or 18 months and at the 5 years of age does not predict allergy at adolescence. Compared with non-allergic children, children with definite allergy at the age of 5 were over 8 times more likely to have allergy and nearly 7 times more likely to have asthma in adolescence. Conclusion An early ascertained diagnosis of allergy, but not suspicions of allergy, predicts prevailing allergy in adolescence. Efforts need to be focused on accurate diagnosis of early childhood allergies.

Kaila, Minna; Rautava, Paivi; Holmberg-Marttila, Doris; Vahlberg, Tero; Aromaa, Minna; Sillanpaa, Matti

2009-01-01

354

A five-year follow-up on the temporal stability of the Ego Impairment Index.  

PubMed

This study investigated the temporal stability of the Ego Impairment Index (EII) over a 5-year period. The EII is based on the Comprehensive System (Exner, 1993) and has shown promise as a measure of internal disturbance and psychopathology (Perry & Braff, 1994; Perry & Viglione, 1991; Perry, Viglione, & Braff, 1992). This study successfully recalled 17 subjects from an original sample of 46 who initially suffered from Major Depression, Melancholic-Type 5 years earlier and were treated with antidepressant medication. These subjects did not differ significantly from those Subjects who were not successfully recalled. The Rorschach and a variety of other measures were administered to the subjects. The results revealed impressive temporal consistency over 5 years: a rank-order, test-retest correlation of .68. The EII was also correlated with some of the measures of overall adaptation. These results are consistent with the notion that the EII is a stable trait-measure of psychopathology. Limitations because of the small subgroup of subjects, although not unusual in longitudinal research, are noted. PMID:16367734

Perry, W; McDougall, A; Viglione, D

1995-02-01

355

The long-term outcome of delinquent children: a 30-year follow-up study.  

PubMed

This study reports the results of a longitudinal study of unselected samples of German delinquent children, stratified by frequency of offences recorded before and after the age of criminal responsibility (14 years). A total of 256 young adults (mean age, 22 years), juvenile offenders and control non-offenders, were assessed using the following: a standardized interview regarding family, child development and life history; a multidimensional personality inventory (the Freiburg Personality Inventory, FPI); a version of the Wechsler Adult Intelligence Scale; a self-report questionnaire on the delinquency for which the subject was not apprehended during childhood; and a questionnaire concerning parental child-rearing style. The subsequent criminal records of subjects were followed over the next 20 years. It was possible to define three outcome groups (non-offenders, persisters and desisters), which differed in many respects. The outcome was significantly predicted by several variables. Psychosocial risk variables were the most effective predictors, followed by personality variables and childhood delinquency for which the subject had not been apprehended. The distinction between early-onset and late-onset delinquency as a predictor of adult criminality proved valid only if non-apprehended childhood offending was taken into account. The implications of the study for preventive intervention are discussed. PMID:20361216

Remschmidt, Helmut; Walter, Reinhard

2010-05-01

356

Long term prognosis of chronic inflammatory demyelinating polyneuropathy: a five year follow up of 38 cases  

PubMed Central

Background Little is known about long term prognosis and course after immune treatments in chronic inflammatory demyelinating polyneuropathy (CIDP). Objective To study long term outcomes and prognostic factors in patients with CIDP. Methods Clinical and electrophysiological findings, responses to immune modulating treatments, and outcomes five years after the start of treatment were reviewed in 38 CIDP patients. Results Patients were treated with corticosteroids (89%), immunoglobulin infusion (45%), or plasmapheresis (34%), and 58% received combined therapy. Five years after treatment was begun, 10 (26%) of the patients had complete remission (lasting >2 years with normal nerve conduction studies), and 23 (61%) had partial remission (able to walk) with (26%) or without (34%) immune treatments. The remaining five patients (13%) still had severe disability (unable to walk) or treatment dependent relapses. Patients with complete remission more often had subacute onset, symmetrical symptoms, good response to initial corticosteroid treatment, and nerve conduction abnormalities predominant in the distal nerve terminals. In contrast, insidious onset, asymmetrical symptoms, and electrophysiological evidence of demyelination in the intermediate nerve segments were associated with refractoriness to treatment or treatment dependent relapse. Conclusions The long term prognosis of CIDP patients was generally favourable, but 39% of patients still required immune treatments and 13% had severe disabilities. Mode of onset, distribution of symptoms, and electrophysiological characteristics may be prognostic factors for predicting a favourable outcome.

Kuwabara, S; Misawa, S; Mori, M; Tamura, N; Kubota, M; Hattori, T

2006-01-01

357

Resin-bonded bridges by dental undergraduates: three-year follow-up.  

PubMed

This study was conducted to evaluate performance and longevity of resin-bonded bridges in patients treated by undergraduate dental students. A total of 62 bridges had been constructed for 53 patients by the students at the School of Dentistry, Karolinska Institute, between 1989 and 1997. After a mean observation period of 35.3 months retention had been lost in 13.6% of 59 bridges examined (4.6% per year). The debonding rate was greater in the mandible (8.3 %/year) than in the maxilla (2.7 %/year), and greatest in the mandibular anterior region (13.4%). Thirty-nine patients with 46 bridges (27 maxillary and 19 mandibular bridges), underwent more detailed clinical examination. No significant differences in bleeding and pocket depth were found between abutment teeth and controls. Bleeding was more frequent at the approximal than the lingual surfaces of the abutment teeth. A questionnaire revealed high patient satisfaction, the resin-bonded bridges meeting their expectations. The study suggests that resin-bonded bridges are an acceptable alternative to conventional bridges. Successful outcome is dependent on stringent case selection, an abutment preparation designed to establish retention form, and meticulous bonding procedures. PMID:11392603

Aslani, E; Johansson, J; Moberg, L E

2001-01-01

358

A 40 years follow-up of dental arch dimensions and incisor irregularity in adults.  

PubMed

Dentoalveolar changes in adulthood have not been extensively documented. Such changes may have important implications for the long-term stability of orthodontic treatment. To analyse occlusal and dentoalveolar changes in adults from the age of 20 years to the age of 60 years. The material comprised 18 Swedish dentists, 16 men and 2 women, with no missing teeth and no prosthodontic or orthodontic treatment. Measurements were recorded on study casts made between 1949 and 1989 at the Department of Stomatognathic Physiology at the Faculty of Odontology in Malmö, thus documenting changes over an average period of 38.4 years. Malocclusion traits, overbite, overjet, dental arch length and width, and Little's irregularity index were registered. There was a significant increase in Little's irregularity index in the mandible (1.0 mm, P < 0.01) and a decrease in arch length in both jaws (0.5-0.9 mm, P < 0.05). The maxillary and mandibular intercanine widths decreased by 0.8 and 1.0 mm, respectively (P < 0.001). The malocclusion traits, overbite, and overjet remained unchanged during the observation period. The results confirm that dentoalveolar changes occur as a continuous process throughout adult life. The findings of potential clinical importance are decreases in arch length and depth, resulting in a decrease in intercanine width and an increase in anterior crowding. In clinical orthodontic practice, these findings have important implications for treatment planning and long-term stability after orthodontic treatment. PMID:22015823

Tsiopas, Nikolaos; Nilner, Maria; Bondemark, Lars; Bjerklin, Krister

2013-04-01

359

Three-year follow-up of lanthanum carbonate therapy in hemodialysis patients.  

PubMed

For 3 years following the start of lanthanum carbonate therapy, effects on other pharmaceutical treatment with sevelamer hydrochloride (SH), calcium carbonate (CC), and vitamin D, and those on clinical condition were examined. Dialysis patients with hyperphosphatemia (89 cases; average age 55.2 years; dialysis history of 10 years; 50 male and 39 female), who agreed to start lanthanum carbonate (LC) administration, were observed for a mean period of 32.6?±?6.2 months. Mean daily dosages of CC and SH before starting LC were 2.68?g and 0.73?g; mean daily dosage amounts of LC, CC, and SH at the time of final evaluation were 0.87?g, 2.30?g, and 0.99?g, respectively. After the application of LC, serum phosphate as well as serum calcium controls were significantly improved, and the amounts of active vitamin D agents applied was significantly increased. In conclusion, LC is useful in managing serum phosphorus levels (P levels), and little incidence of hypercalcemia suggests favorable concomitant use with active vitamin D agents in LC therapy. PMID:23586508

Takeuchi, Kazuhisa; Matsuda, Etsuko; Sekino, Makoto; Hasegawa, Yukiko; Kamo, Yoshie; Kikuchi, Natsue; Sekino, Hiroshi

2013-04-01

360

Brooding and reflection: Rumination predicts suicidal ideation at one-year follow up in a community sample  

PubMed Central

The cognitive processes underlying suicidal thinking and behavior are not well-understood. The present study examined brooding and reflection, two dimensions of rumination, as predictors of suicidal ideation among a community sample of 1,134 adults. Participants completed self-report measures of rumination and depression, and a semi-structured clinical interview that included an assessment of suicidal ideation, at baseline and one-year follow up. Brooding was more strongly related to degree of ideation at baseline than was reflection. However, both brooding and reflection predicted whether an individual thought about suicide at one-year follow up, even after adjusting for baseline suicidal ideation. Symptoms of depression mediated the relationship between brooding and ideation but not between reflection and ideation. Implications for the nature of thought processes that result in suicidal thinking are discussed.

Nolen-Hoeksema, Susan

2010-01-01

361

Longitudinal pulmonary functional loss in cotton textile workers: A 5-year follow-up study  

PubMed Central

Background Occupational exposure to cotton dust causes several diseases affecting the lungs, but only limited information is available on effects of long-term exposure. In this study, we aimed to evaluate longitudinal changes in selected parameters of pulmonary function in textile workers. Material/Methods This prospective cohort study began with 196 textile workers in 2006 and was completed in 2011 with 49 workers. We used standardized tests for pulmonary function on participants on the first day of the workweek in June of 2006 and 2011. Environmental samples of cotton dust were gathered with a vertical elutriator. Loss of pulmonary function was assessed based on gender and smoking status. Results The mean number of years participants worked in the textile factory was 7.61±1.83 years, and the mean age was 35.3+5.8 years. The annual FEV1 loss of all workers was 53.2 ml, giving a ratio of annual FEV1 loss to baseline FEV1 of 1.4%. Pulmonary function parameters of all participants in 2011 were significantly lower than those in 2006 (for all, p<0.05). In both surveys, pulmonary function in current smokers was lower, but this difference was not significant (p>0.05). Conclusions This study provides the first data on pulmonary functional loss in Turkish textile workers and supports the findings of other cohort studies that workers with long-term exposure to cotton dust may lose some pulmonary function. The ratio of annual FEV1 loss to baseline FEV1 appears to be a more accurate and comparable method than annual FEV1 loss for evaluating pulmonary functional loss.

Kahraman, Hasan; Sucakli, Mustafa Haki; Kilic, Talat; Celik, Mustafa; Koksal, Nurhan; Ekerbicer, Hasan Cetin

2013-01-01

362

Attrition in a 30-year follow-up of a perinatal birth risk cohort: factors change with age  

PubMed Central

Background. Attrition is a major cause of potential bias in longitudinal studies and clinical trials. Attrition rate above 20% raises concern of the reliability of the results. Few studies have looked at the factors behind attrition in follow-ups spanning decades. Methods. We analyzed attrition and associated factors of a 30-year follow-up cohort of subjects who were born with perinatal risks for neurodevelopmental disorders. Attrition rates were calculated at different stages of follow-up and differences between responders and non-responders were tested. To find combinations of variables influencing attrition and investigate their relative importance at birth, 5, 9, 16 and 30 years of follow-up we used the random forest classification. Results. Initial loss of potential participants was 13%. Attrition was 16% at five, 24% at nine, 35% at 16 and 46% at 30 years. The only group difference that emerged between responders and non-responders was in socioeconomic status (SES). The variables identified by random forest classification analysis were classified into Birth related, Development related and SES related. Variables from all these categories contributed to attrition, but SES related variables were less important than birth and development associated variables. Classification accuracy ranged between 0.74 and 0.96 depending on age. Discussion. Lower SES is linked to attrition in many studies. Our results point to the importance of the growth and development related factors in a longitudinal study. Parents’ decisions to participate depend on the characteristics of the child. The same association was also seen when the child, now grown up, decided to participate at 30 years. In addition, birth related medical variables are associated with the attrition still at the age of 30. Our results using a data mining approach suggest that attrition in longitudinal studies is influenced by complex interactions of a multitude of variables, which are not necessarily evident using other multivariate techniques.

Hokkanen, Laura; Laasonen, Marja; Tuulio-Henriksson, Annamari; Virta, Maarit; Lipsanen, Jari; Tienari, Pentti J.; Michelsson, Katarina

2014-01-01

363

Children and adolescents with psychotic disorder not otherwise specified: A 2- to 8-year follow-up study  

Microsoft Academic Search

Although psychotic phenomena in children with disruptive behavior disorders are more common than expected, their prognostic significance is unknown. To examine the outcome of pediatric patients with atypical psychoses, a group of 26 patients with transient psychotic symptoms were evaluated with clinical and structured interviews at the time of initial contact (mean age, 11.6 ± 2.7 years) and at follow-up

Rob Nicolson; Marge Lenane; Frances Brookner; Peter Gochman; Sanjiv Kumra; Lori Spechler; Jay N. Giedd; Gunvant K. Thaker; Marianne Wudarsky; Judith L. Rapoport

2001-01-01

364

Service Utilization and Cost of Community Care for Discharged State Hospital Patients: A 3Year Follow-Up Study  

Microsoft Academic Search

Objective: This study examined the mental health service utilization and costs of 321 discharged state hospital patients during a 3-year follow-up period compared with costs if the patients had remained in the hospital. Method: The study subjects were long-stay pa- tients discharged from Philadelphia State Hospital after 1988. A longitudinal integrated da- tabase on all mental health and medical services

Aileen B. Rothbard; Eri Kuno; Arie P. Schinnar; Trevor R. Hadley; Roland Turk

365

One-Year Follow-Up of Cognitive-Behavioral Therapy for Obese Individuals With Binge Eating Disorder  

Microsoft Academic Search

The results of a 1-year posttreatment follow-up of 93 obese women diagnosed as having binge eating disorder (BED) and treated with group cognitive-behavioral therapy (CBT) followed by weight loss treatment are described. The group as a whole maintained both reductions in binge eating and abstinence rates fairly well. However, they regained the weight lost during treatment. Those who stopped binge

W. Stewart Agras; Christy F. Telch

2000-01-01

366

Depression and Suicidal Ideation After Predictive Testing for Huntington's Disease: A Two-Year Follow-up Study  

Microsoft Academic Search

The present study reports a two-year follow-up of psychological effects of predictive testing for Huntington's disease. Questionnaires assessing depression, general health, well-being, self injurious behavior, life satisfaction, and lifestyle were completed by 35 carriers and 58 non-carriers before the predictive test, and 2, 6, 12, and 24 months afterwards. Both carriers and non-carriers showed high suicidal ideation before the predictive

Maria U. Larsson; Mary A. Luszcz; Tarja-Brita Robins Wahlin

2006-01-01

367

Homeopathic treatment of patients with chronic sinusitis: A prospective observational study with 8 years follow-up  

Microsoft Academic Search

BACKGROUND: An evaluation of homeopathic treatment and the outcomes in patients suffering from sinusitis for ?12 weeks in a usual care situation. METHODS: Subgroup analysis including all patients with chronic sinusitis (ICD-9: 473.9; ?12 weeks duration) of a large prospective multicentre observational study population. Consecutive patients presenting for homeopathic treatment were followed-up for 2 years, and complaint severity, health-related quality

Claudia M Witt; Rainer Lüdtke; Stefan N Willich

2009-01-01

368

Family burden and coping strategies in schizophrenia: 1-year follow-up data from the BIOMED I study  

Microsoft Academic Search

Background: To date, only few data are available on how family burden in schizophrenia changes over time. In addition, no study has\\u000a explored how such factors as coping styles and social support influence burden over time. This paper presents the 1-year follow-up\\u000a data from the BIOMED I study on family burden and coping strategies in schizophrenia. Methods: A sample of

L. Magliano; G. Fadden; M. Economou; T. Held; M. Xavier; M. Guarneri; C. Malangone; C. Marasco; M. Maj

2000-01-01

369

Mortality After Exposure to Polychlorinated Biphenyls and Polychlorinated Dibenzofurans: A 40Year Follow-up Study of Yusho Patients  

Microsoft Academic Search

A 40-year follow-up study was conducted to examine mortality among 1,664 patients in Japan suffering from ''Yusho,'' a disease caused by ingestion of rice oil contaminated with polychlorinated biphenyls and polychlorinated dibenzofurans. To evaluate the effects of exposure on mortality, the authors calculated standardized mortality ratios. National mortality rates for major causes of death were used as reference points. A

Daisuke Onozuka; Takesumi Yoshimura; Satoshi Kaneko; Masutaka Furue

370

Risk factors for myocardial infarction and death in newly detected NIDDM: the Diabetes Intervention Study, 11-year follow-up  

Microsoft Academic Search

Summary   The Diabetes Intervention Study (DIS) is a prospective population-based multicentre trial of newly detected cases of non-insulin-dependent\\u000a diabetes mellitus (NIDDM). This report analyses the risk factors for subsequent coronary heart disease and all-cause death\\u000a during the 11-year follow-up. The prognostic significance of the categories of the NIDDM Policy Group was validated with respect\\u000a to the incidence of coronary heart

M. Hanefeld; S. Fischer; U. Julius; J. Schulze; U. Schwanebeck; H. Schmechel; H. J. Ziegelasch; J. Lindner

1996-01-01

371

Long-Term Survival after Stroke: 30 Years of Follow-Up in a Cohort, the Copenhagen City Heart Study  

Microsoft Academic Search

Background and Purpose: Only few have studied long-term survival after stroke. Such knowledge is essential for the evaluation of the current and future burden of stroke. The present study presents up to 30 years of follow-up of patients after a first-ever stroke. Methods: Participants in the Copenhagen City Heart Study who experienced a first-ever stroke from 1978 to the end

Gudrun Boysen; Jacob Louis Marott; Morten Grønbæk; Houry Hassanpour; Thomas Truelsen

2009-01-01

372

Comparison of early and 1-year follow-up results of conventional hemorrhoidectomy and hemorrhoid artery ligation: a randomized study  

Microsoft Academic Search

Background and aimsDoppler-guided hemorrhoid artery ligation is a new approach for treating hemorrhoids. Early and 1-year follow-up results of the procedure are presented and compared with those of closed scissors hemorrhoidectomy in a prospective randomized study.Patients and methodsSixty consecutively recruited patients were randomized into two groups: group A ( n=30) was treated with standardized closed scissors hemorrhoidectomy and group B

Attila Bursics; Krisztina Morvay; Péter Kupcsulik; Lajos Flautner

2004-01-01

373

Association of Reduced Physical Activity and Quantitative Ultrasound Measurements: A 6Year Follow-up Study of Adolescent Girls  

Microsoft Academic Search

Sonographic parameters of the heel were recorded in order to investigate the effects of changes in physical activities among\\u000a 140 healthy growing peripubertal Caucasian girls. Calcaneal quantitative ultrasound measurements (Hologic Sahara) were recorded\\u000a at baseline and 2- and 6-year follow-up. Broadband ultrasound attenuation, speed of sound (SOS), and T scores were documented.\\u000a Altogether, 30 girls reduced their physical activity by

E. Rautava; M. Lehtonen-Veromaa; T. Möttönen; H. Kautiainen; O. J. Heinonen; J. Viikari

2006-01-01

374

Four-year follow-up of a case of acute multiple sclerosis of the Marburg type  

Microsoft Academic Search

We describe the clinical course, treatment and magnetic resonance findings during a four-year follow-up of a patient with acute multiple sclerosis of the Marburg type, treated with steroid and mannitol therapy, who survived the first bout. Although the course of the disease was clinically indistinguishable from relapsing-remitting multiple sclerosis, our case was characterized by peculiar features. These included the need

F. Giubilei; A. Sarrantonio; P. Tisei; C. Gasperini; M. Salvetti

1997-01-01

375

Piriformis muscle syndrome in 19 patients treated by tenotomy – A 1- to 16-year follow-up study  

Microsoft Academic Search

.   We treated 19 patients with piriformis muscle syndrome. All patients complained of pain in the buttocks and the posterior\\u000a thigh. Clinically the buttock was tender and passive stretching increased the pain. In ten patients skin sensation was reduced\\u000a and three had a limp. All patients were treated with tenotomy. At follow-up after an average of 8 (1–16) years, eight

K. Indrekvam; E. Sudmann

2002-01-01

376

Laparoscopic Sleeve Gastrectomy in Patients over 59 Years: Early Recovery and 12Month Follow-Up  

Microsoft Academic Search

Background  Bariatric surgery has shown to be safe for patients over 60 years with good results especially considering resolving of comorbidities.\\u000a Sleeve gastrectomy is considered to be safer than gastric bypass (GBP) and more effective than gastric banding with less adverse\\u000a symptoms. Weight loss may be more modest than after GBP, but the effect on vitamins may also be milder.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  Since 2007,

Marja Kaarina Leivonen; Anne Juuti; Nabil Jaser; Harri Mustonen

2011-01-01

377

Cardiac Anderson-Fabry disease: Lessons from a 25-year-follow up.  

PubMed

Sarcomeric hypertrophic cardiomyopathy (HCM) is the most common genetic cause of unexplained left ventricular hypertrophy and has no specific treatment. Anderson-Fabry disease (AFD) is rare and usually multisystemic, but occasionally expresses clinically as a predominantly cardiac phenotype mimicking HCM. We describe an illustrative case of a patient followed regularly for 25 years with a diagnosis of familial HCM and no identified sarcomeric mutations. Next-generation sequencing analysis identified a novel pathogenic mutation in the GLA gene, leading to a diagnosis of previously unknown multisystemic AFD, with consequent implications for the patient's treatment and prognosis and familial screening. PMID:24830310

Brito, Dulce; Miltenberger-Miltenyi, Gabriel; Moldovan, Oana; Navarro, Carmen; Madeira, Hugo Costa

2014-04-01

378

Multiple personality. A single case study with a 15 year follow-up.  

PubMed

A review of the literature relating to multiple personality is presented together with a study of a single case of hysterical aetiology that demonstrates the development of multiple personality from a fugue amnesic state. A re-examination of this case after 15 years without significant psychotherapeutic intervention demonstrates a tendency towards remission. The view that multiple personality is a form of fugue, not necessarily hysterical, in which an alternative personality is adopted and that this behaviour is reinforced by the attention that it receives, is discussed. PMID:1118527

Cutler, B; Reed, J

1975-02-01

379

Pregnancies in an 18Year Follow-up after Biliopancreatic Diversion  

Microsoft Academic Search

Background: 239 pregnancies occurred in 1136 women who had undergone biliopancreatic diversion (BPD). Methods: There were\\u000a 73 abortions, and 14 pregnancies are presently in their course. The 152 term pregnancies (six twins) occurred in 129 women\\u000a 2-173 months (mean 42.7) after BPD. Mean age and current excess weight were 31.4 years (20-42) and 29.1% (-6.9-78.2), and\\u000a mean excess weight loss

Daniele Friedman; Sonia Cuneo; Mario Valenzano; Giuseppe Maria Marinari; Gian Franco Adami; Ezio Gianetta; Enrico Traverso; Nicola Scopinaro

1995-01-01

380

Prospective Predictors of Suicidal Behavior in BPD at 6 Year Follow-up  

PubMed Central

Objective Recurrent suicidal behavior is a defining characteristic of BPD. Although most patients achieve remission of suicidal behaviors over time, 3% to 10% die by suicide, raising the question of whether there is a high risk suicidal subtype in BPD. We are conducting the first longitudinal study of suicidal behavior in BPD to identify prospective predictors of suicide attempts, and characterize BPD patients at highest risk for suicide completion. Method Demographic, diagnostic, clinical and psychosocial risk factors assessed at baseline were examined for predictive association with medically significant suicide attempts using Cox proportional hazards models. Prospective predictors were defined for subjects completing 6 or more years in the study and compared to earlier intervals. Results Among 90 subjects, 25 (27.8%) made at least one suicide attempt in the interval, most occurring in the first two years. Risk of attempt was increased by: a.) low socioeconomic status, b.) poor psychosocial adjustment, c.) a family history of suicide d.) prior psychiatric hospitalization; e.) absence of any outpatient treatment prior to the attempt. Higher global functioning at baseline decreased risk. Conclusion Risk factors predictive of suicide attempts change over time. Acute stressors such as MDD were predictive only in the short term (12 mos.), while poor psychosocial functioning had persistent and long term effects on suicide risk. Half of BPD patients have poor psychosocial outcomes despite symptomatic improvement. A social and vocational rehabilitation model of treatment is needed to decrease suicide risk and optimize long term outcomes in BPD.

Soloff, Paul H.; Chiappetta, Laurel

2012-01-01

381

Cytomegalovirus Antibody Levels, Inflammation, and Mortality Among Elderly Latinos Over 9 Years of Follow-up  

PubMed Central

This study examined the relation between immune response to cytomegalovirus (CMV) and all-cause and cardiovascular disease (CVD) mortality, and possible mediating mechanisms. Data were derived from the Sacramento Area Latino Study on Aging, a population-based study of older Latinos (aged 60–101 years) in California followed in 1998–2008. CMV immunoglobulin G (IgG), tumor necrosis factor, and interleukin-6 were assayed from baseline blood draws. Data on all-cause and CVD mortality were abstracted from death certificates. Analyses included 1,468 of 1,789 participants. For individuals with CMV IgG antibody titers in the highest quartile compared with lower quartiles, fully adjusted models showed that all-cause mortality was 1.43 times (95% confidence interval: 1.14, 1.79) higher over 9 years. In fully adjusted models, the hazard of CVD mortality was also elevated (hazard ratio = 1.35, 95% confidence interval: 1.01, 1.80). A composite measure of tumor necrosis factor and interleukin-6 mediated a substantial proportion of the association between CMV and all-cause (18.9%, P < 0.001) and CVD (29.0%, P = 0.02) mortality. This study is the first known to show that high CMV IgG antibody levels are significantly related to mortality and that the relation is largely mediated by interleukin-6 and tumor necrosis factor. Further studies investigating methods for reducing IgG antibody response to CMV are warranted.

Roberts, Eric T.; Haan, Mary N.; Dowd, Jennifer Beam; Aiello, Allison E.

2010-01-01

382

Changing network support for drinking: network support project 2-year follow-up.  

PubMed

The Network Support Project was designed to determine whether a treatment could lead patients to change their social network from one that supports drinking to one that supports sobriety. This study reports 2-year posttreatment outcomes. Alcohol-dependent men and women (N = 210) were randomly assigned to 1 of 3 outpatient treatment conditions: network support (NS), network support + contingency management (NS + CM), or case management (CaseM, a control condition). Analysis of drinking rates indicated that the NS condition yielded up to 20% more days abstinent than the other conditions at 2 years posttreatment. NS treatment also resulted in greater increases at 15 months in social network support for abstinence, as well as in AA attendance and AA involvement than did the other conditions. Latent growth modeling suggested that social network changes were accompanied by increases in self-efficacy and coping that were strongly predictive of long-term drinking outcomes. The findings indicate that a network support treatment can effect long-term adaptive changes in drinkers' social networks and that these changes contribute to improved drinking outcomes in the long term. PMID:19309183

Litt, Mark D; Kadden, Ronald M; Kabela-Cormier, Elise; Petry, Nancy M

2009-04-01

383

Prognostic value of coronary CT angiography on long-term follow-up of 6.9 years.  

PubMed

Long term follow-up of coronary CT angiography (CCTA) is scarce. The aim of the present study was to assess the prognostic value of CCTA over a follow-up period of more than 6 years. 218 Patients were included undergoing 64-slice CCTA. Images were analysed with regard to the presence of nonobstructive (<50 %) or obstructive (50 % stenosis) coronary artery disease (CAD). Major adverse cardiovascular events (MACE) were defined as death, nonfatal myocardial infarction or urgent coronary revascularization. CCTA revealed normal coronaries in 49, nonobstructive lesions in 94, and obstructive CAD in 75 patients. During a median follow-up period of 6.9 years, MACE occurred in 45 patients (21 %). Annual MACE rates were 0.3, 2.7, and 6.0 % (p = 0.001), for patients with normal CCTA, nonobstructive, and obstructive CAD, respectively. Multivariate Cox regression analysis identified the number of segments with plaques [hazard ratio (HR) 1.18, p = 0.002] as well as the presence of obstructive lesions (HR 2.28, p = 0.036) as independent predictors of MACE. The present study extends the predictive value of CCTA over more than 6 years. Patients with normal coronary arteries of CCTA continue to have an excellent cardiac prognosis, while outcome is progressively worse in patients with nonobstructive and obstructive CAD. PMID:24710707

Dougoud, Svetlana; Fuchs, Tobias A; Stehli, Julia; Clerc, Olivier F; Buechel, Ronny R; Herzog, Bernhard A; Leschka, Sebastian; Alkadhi, Hatem; Kaufmann, Philipp A; Gaemperli, Oliver

2014-06-01

384

A 10 year follow-up study after Roux-Elmslie-Trillat treatment for cases of patellar instability  

PubMed Central

Background A retrospective study concerning patients presenting with patella instability, treated using a Roux-Elmslie-Trillat reconstruction operation and followed up for 10 years following surgery, is presented. Methods Pre-operative and follow-up radiographic evaluation included the weight-bearing anteroposterior and merchant views. Evaluation was carried out using the Insall-Salvati index, sulcus and congruence angle. The Roux-Elmslie-Trillat reconstruction operation was performed on 18 patients. The clinical evaluation at follow-up was performed using the Knee-Society-Score (KSS) and Tegner-Score. Results Subjective results of the operation were classed as excellent or good in 16 of the 18 patients ten years after surgery; persistent instability of the patella was recorded in only one of the 18 patients. The majority of patients returned to the same level of sporting activity after surgery as they had participated in before injury. Conclusions The Roux-Elmslie-Trillat procedure could be recommended in cases presenting with an increased q-angle, trochlea dysplasia or failed soft tissue surgery. In the present study the majority of patients report a return to previous sporting activity ten years after surgery.

2011-01-01

385

10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study  

PubMed Central

Summary Background In the 2·8 years of the Diabetes Prevention Program (DPP) randomised clinical trial, diabetes incidence in high-risk adults was reduced by 58% with intensive lifestyle intervention and by 31% with metformin, compared with placebo. We investigated the persistence of these effects in the long term. Methods All active DPP participants were eligible for continued follow-up. 2766 of 3150 (88%) enrolled for a median additional follow-up of 5·7 years (IQR 5·5–5·8). 910 participants were from the lifestyle, 924 from the metformin, and 932 were from the original placebo groups. On the basis of the benefits from the intensive lifestyle intervention in the DPP, all three groups were offered group-implemented lifestyle intervention. Metformin treatment was continued in the original metformin group (850 mg twice daily as tolerated), with participants unmasked to assignment, and the original lifestyle intervention group was offered additional lifestyle support. The primary outcome was development of diabetes according to American Diabetes Association criteria. Analysis was by intention-to-treat. This study is registered with ClinicalTrials.gov, number NCT00038727. Findings During the 10·0-year (IQR 9·0–10·5) follow-up since randomisation to DPP, the original lifestyle group lost, then partly regained weight. The modest weight loss with metformin was maintained. Diabetes incidence rates during the DPP were 4·8 cases per 100 person-years (95% CI 4·1–5·7) in the intensive lifestyle intervention group, 7·8 (6·8–8·8) in the metformin group, and 11·0 (9·8–12·3) in the placebo group. Diabetes incidence rates in this follow-up study were similar between treatment groups: 5·9 per 100 person-years (5·1–6·8) for lifestyle, 4·9 (4·2–5·7) for metformin, and 5·6 (4·8–6·5) for placebo. Diabetes incidence in the 10 years since DPP randomisation was reduced by 34% (24–42) in the lifestyle group and 18% (7–28) in the metformin group compared with placebo. Interpretation During follow-up after DPP, incidences in the former placebo and metformin groups fell to equal those in the former lifestyle group, but the cumulative incidence of diabetes remained lowest in the lifestyle group. Prevention or delay of diabetes with lifestyle intervention or metformin can persist for at least 10 years. Funding National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

2011-01-01

386

One year follow up study of primary and transitional progressive multiple sclerosis  

PubMed Central

OBJECTIVE—To document clinical and magnetic resonance imaging (MRI) characteristics of a large cohort of primary and transitional progressive multiple sclerosis (PP and TP MS) patients over one year.?INTRODUCTION—Patients with PP or TP MS have been shown to have low brain T2 and T1 lesion loads and slow rates of new lesion formation with minimal gadolinium enhancement, despite their accumulating disability. Serial evaluation of these patients is needed to elucidate the pathological processes responsible for disease progression and to identify clinical and MRI measures which can monitor these processes in treatment trials.?METHOD—Patients, recruited from six European centres, underwent two assessments on the expanded disability status scale (EDSS) and MRI of the brain and spinal cord, 1 year apart.?RESULTS—Of the 167 patients studied (137 with PP MS and 30 with TP MS), 41 (25%; 35 PP and six TP) showed a one step increase in the EDSS. The mean number of new brain lesions seen was 0.88 in the PP group and 0.47 in the TP MS group. Both groups demonstrated change in T2 lesion load over the year (p?0.002), with median percentage changes of 7.3% in the PP group and 10.8% in the TP MS group. The PP group also showed a significant change in T1 load (p< 0.001, median change 12.6%). The number of new cord lesions seen was small (mean of 0.14 in the PP group and no new cord lesions in the TP group). Both groups demonstrated a decrease in cord cross sectional area (p< 0.001, median changes; PP 3.8%, TP 4.9%), but only the PP group showed evidence of significant brain atrophy (p< 0.001, 0.95%).?CONCLUSION—Although the monitoring of disease progression in this patient group is difficult, this study demonstrates changes in both lesion load and atrophy, which, if shown to correlate with clinical change over a longer time will facilitate therapeutic trial design.??

Stevenson, V; Miller, D; Leary, S; Rovaris, M; Barkhof, F; Brochet, B; Dousset, V; Dousset, V; Filippi, M; Hintzen, R; Montalban, X; Polman, C; Rovira, A; de Sa, J; Thompson, A

2000-01-01

387

Experience with Silastic prostheses in the rheumatoid hand. A 5-year follow-up.  

PubMed Central

Nine patients with rheumatoid arthritis, who had Silastic prostheses (Swanson's) introduced into 34 metacarpophalangeal joints, were reviewed 5 years after surgery. The most important long-term advantage conferred by the introduction of prostheses was pain relief; functional benefit was marginal. The majority of prostheses eventually fractured but this did not necessarily lead to a functional deterioration. Impairment of function was usually the result of loss of flexion at the metacarpophalangeal joints, but it was sometimes due to excessive instability after fracture of the prostheses. It is suggested that Silastic joint replacement may be a worthwhile procedure in rheumatoid patients with moderate destruction or deformity of the metacarpophalangeal joints when pain is a predominant feature. Significant functional improvement can be anticipated only when secondary to pain relief. Images

Kay, A G; Jeffs, J V; Scott, J T

1978-01-01

388

Use of screws and cement in primary TKA with up to 20 years follow-up.  

PubMed

The purpose of this study was to investigate screws and cement for large tibial bone defects during primary TKA. Of 14,686 consecutive primary TKAs performed between December 1988 and February 2010, 256 received screws and cement for tibial defects. Cox regression was used for the analysis. 20-year survival probability was 0.9897 (screws) and 0.9339 (no screws) (P = .4225 log-rank). Tibial bone condition was significantly worse in knees receiving screws (P < .0001) with 73.0% having defects in the screws group and 3.4% (P < .0001) for non-screws. Radiolucency appeared in 13.7% (screws) and 6.4% (no screws) postoperatively. Screws were $137 each, wedges $910 to $2240. Knees with tibial defects and screws performed similarly if not better than knees without defects at substantially lower cost than alternatives. PMID:24456788

Berend, Michael E; Ritter, Merrill A; Keating, E Michael; Jackson, Michael D; Davis, Kenneth E

2014-06-01

389

Mineral trioxide aggregate as pulp capping agent for primary teeth pulpotomy: 2 year follow up study.  

PubMed

The aim of the present study was to clinically and radiographically evaluate Mineral Trioxide Aggregate (MTA) as an agent for pulpotomy in primary teeth and to compare it with that of formocresol (FC) pulpotomy. Nineteen children between the ages of 6 to 8 years with 40 carious primary molars were treated with pulpotomy using either FC or MTA. All the molars were evaluated clinically and radiographically at regular intervals over a twenty four month period. The observations were tabulated and statistically analyzed. Eighty five percent success was observed with FC pulpotomy whereas MTA showed 95% success. MTA showed a higher clinical and radiographic success rate than FC. MTA may be a favorable material for pulpotomy in primary teeth whose pulps have been compromised by a carious or mechanical pulp exposure. PMID:19725237

Subramaniam, Priya; Konde, Sapna; Mathew, Somy; Sugnani, Sony

2009-01-01

390

[Erythema infectiosum in pregnancy. A follow-up of children after 2 years].  

PubMed

During an epidemic of erythema infectiosum in Norway 1984-86, infection with human parvovirus B19 was diagnosed in 22 pregnant women by detection of specific IgM antibodies. Information about the outcome of pregnancy was obtained in 19 cases. 17 women delivered live babies. In two cases, spontaneous abortion occurred in week 16 of the pregnancy. In 11 cases, cord blood and serum samples were obtained from the children at an age of between six and 15 months. No specific IgM antibodies were found in cord blood. Clinical information on 16 children at two years of age revealed normal growth and development in 15 cases. One child was hyperactive and showed delayed language development. B19 IgG antibodies were detected in three children with normal growth and development. According to our findings, there was no association between infection with human parvovirus B19 in pregnancy and congenital abnormalities. PMID:8191425

Bruu, A L; Flugsrud, L B

1994-01-30

391

Six-year clinical and immunologic follow-up of workers exposed to trimellitic anhydride  

SciTech Connect

We report a 6-year study from 1979 through 1985 of workers exposed to trimellitic anhydride (TMA) in three groups of volunteers. Twenty-nine percent of workers (5/17) originally studied had immunologically induced respiratory disease. Subsequent to this evaluation, increased environmental control of TMA exposure was instituted. Since that time, there have been decreasing clinical symptoms and decreasing levels of antibody against TMA conjugated to human serum albumin. These long-term studies originally used radioimmunoassays, but enzyme-linked immunoassays against TMA-conjugated proteins are now demonstrated to be equally appropriate and are more cost-effective. With appropriate clinical and immunologic studies, immunologic airway reactions to TMA may be identified and then prevented by environmental control to decrease inhalation exposure to TMA. This is likely applicable to certain other chemical antigens that immunize by inhalation.

Boxer, M.B.; Grammer, L.C.; Harris, K.E.; Roach, D.E.; Patterson, R.

1987-08-01

392

Psychosocial and developmental factors in failure to thrive: one- to three- year follow-up.  

PubMed

Fifteen infants and children with a diagnosis of failure to thrive (FTT) were followed at one to three years postdischarge. Data were gathered from in-home interviews, psychosocial questionnaires, measurement of present height and weight, and administration of the Developmental Profile. Nine of the 15 children were still failing to thrive; the other 6 were considered recovered. The nonthriving group consisted of three subgroups: (1) developmentally retarded, (2) organic basis FTT, and (3) psychosocial FTT. The developmentally retarded children were significantly different in that they required more attention, had greater constipation, and engaged in less tantrum behavior. Further, they were significantly more impaired in the physical, self-help, and social areas of development. The difficulties in diagnosis and treatment of FTT children are discussed. Suggestions for the enhancement of medical management of this complex and life-threatening disorder are offered. PMID:6168654

White, J L; Malcolm, R; Roper, K; Westphal, M C; Smith, C

1981-09-01

393

Clinical experience with In-Ceram Spinell crowns: 5-year follow-up.  

PubMed

Prompted by increased patient requests for esthetic treatment, restorative clinicians have evaluated a variety of new materials and procedures. This study reports on 5 years' experience with In-Ceram Spinell all-ceramic crowns. A total of 40 anterior crowns were positioned in 13 patients from October 1995 to December 1998. The clinical examination was made following modified California Dental Association/Ryge criteria. Final evaluation was carried out in October 2000, for an observation period of 22 to 60 months (mean 50 months). Only one failure was recorded, and the fractured crown needed to be replaced; according to Kaplan-Meier analysis, the estimated success rate was 97.5%. A thorough description of the clinical procedures through which anterior teeth can be successfully treated with all-ceramic Spinell crowns is described. PMID:12516824

Fradeani, Mauro; Aquilano, Augusto; Corrado, Marcantonio

2002-12-01

394

p53 Expression in a Malignant Mesothelioma Patient during Seven-Year Follow-up  

PubMed Central

Malignant mesothelioma (MM) is the aggressive tumor of serosal surfaces. There are crude pathogenetic results regarding the biology of MM. Coordinated upregulations of p53 gene expression are shown in malignancies. We believed that there are changes in the p53 expression with transformation from reactive hyperplasia to MM. A 65-year-old male was admitted the hospital because of left pleuritic chest pains in 2004. Chest computed tomography (CT) results showed left pleural effusions with loculation and pleural thickening. Pathologic findings revealed reactive mesothelial hyperplasia. In 2008, the patient again felt left pleuritic chest pains. Chest CT showed progressive thickening of the left pleura. Pathologic diagnosis was atypical mesothelial hyperplasia. In 2011, chest CT showed progressive thickening of his left pleura. He was diagnosed with well-differentiated papillary mesothelioma. Serial change was analyzed by immunohistochemical staining for p53 of pleural tissues. There were no remarkable changes in p53 expressions during the transformation to MM.

Koo, So-My; Kim, Dong Won; Kim, Ki-Up; Kim, Yang-Ki

2014-01-01

395

A retrospective analysis of osseotite NT implants in clinical practice: 1-year follow-up.  

PubMed

This article reports the preliminary results from a clinical study involving the use of implants with a natural taper design in edentulous and partially edentulous patients. Implants were followed for at least 12 months after occlusal loading. Three hundred nine implants were placed by two periodontists (176 maxillary, 133 mandibular; 198 anterior, 111 posterior). Digital radiographs were taken immediately after implant placement and 1 year after occlusal loading. Computerized measurements were made, with distances calculated between the implant restorative platforms and the greatest heights of interproximal bone on both interproximal surfaces at the time of implant placement and 12 months postplacement. At the 12-month recall appointments, it was noted that 8 of the 309 implants had failed. Osseotite NT implants can be used in the treatment of edentulous and partially edentulous patients using two-stage, single-stage, and immediate occlusal loading protocols with survival rates equivalent to those seen for cylindrically shaped implants. PMID:16939015

Drago, Carl J; Del Castillo, Robert A

2006-08-01

396

Obesity in Men With Childhood ADHD: A 33-Year Controlled, Prospective, Follow-up Study  

PubMed Central

OBJECTIVE: To compare BMI and obesity rates in fully grown men with and without childhood attention-deficit/hyperactivity disorder (ADHD). We predicted higher BMI and obesity rates in: (1) men with, versus men without, childhood ADHD; (2) men with persistent, versus men with remitted, ADHD; and (3) men with persistent or remitted ADHD versus those without childhood ADHD. METHODS: Men with childhood ADHD were from a cohort of 207 white boys (referred at a mean age of 8.3 years), interviewed blindly at mean ages 18 (FU18), 25 (FU25), and 41 years (FU41). At FU18, 178 boys without ADHD were recruited. At FU41, 111 men with childhood ADHD and 111 men without childhood ADHD self-reported their weight and height. RESULTS: Men with childhood ADHD had significantly higher BMI (30.1 ± 6.3 vs 27.6 ± 3.9; P = .001) and obesity rates (41.4% vs 21.6%; P = .001) than men without childhood ADHD. Group differences remained significant after adjustment for socioeconomic status and lifetime mental disorders. Men with persistent (n = 24) and remitted (n = 87) ADHD did not differ significantly in BMI or obesity rates. Even after adjustment, men with remitted (but not persistent) ADHD had significantly higher BMI (B: 2.86 [95% CI: 1.22 to 4.50]) and obesity rates (odds ratio: 2.99 [95% CI: 1.55 to 5.77]) than those without childhood ADHD. CONCLUSIONS: Children with ADHD are at increased risk of obesity as adults. Findings of elevated BMI and obesity rates in men with remitted ADHD require replication.

Cortese, Samuele; Ramos Olazagasti, Maria A.; Klein, Rachel G.; Proal, Erika; Mannuzza, Salvatore

2013-01-01

397

Five-Year Follow-Up of Parapapillary Atrophy: The Beijing Eye Study  

PubMed Central

Purpose To assess longitudinal changes in parapapillary atrophy in the adult population of Greater Beijing. Methods The population-based Beijing Eye Study 2006 included 3251 subjects who had participated in the Beijing Eye Study 2001 and returned for re-examination. The mean age was 60.4±10.1 years. Using optic disc photographs, we measured parapapillary atrophy which was divided into alpha zone and beta zone. Results Overall progression rate of alpha zone was seen in 0.6±0.1% (95% confidence interval (CI):0.3,0.9) of the subjects and of beta zone in 8.2±0.5% (95%CI:7.2,9.1) of the subjects. In binary regression analysis, rate of progression of alpha zone was significantly associated higher age (P?=?0.04) and the co-progression of zone Beta (P<0.001). Rate of progression of beta zone was significantly associated with higher age (P<0.001; odds ratio (OR):1.11;95%CI:1.10,1.14), higher intraocular pressure (P<0.001;OR:1.10;95%CI:1.05,1.14), higher myopic refractive error (P<0.001;OR:0.71; 95%CI:0.67,0.75), rural region of habitation (P?=?0.002;OR: 0.58; 95%CI:0.41,0.82), presence of glaucomatous optic nerve damage (P<0.001;OR:2.89; 95%CI:1.62,5.14), co-progression of alpha zone (P<0.001;OR:7.13;95%CI:2.43,20.9), absence of arterial hypertension (P?=?0.03;OR: 0.70; 95%CI:0.51,0.96), and thicker central corneal thickness (P?=?0.02;OR:1.01;95%CI:1.00,1.01). Subjects with a non-glaucomatous optic nerve damage (n?=?22) as compared to the remaining subjects did not vary in the progression rate of alpha zone (0.0% versus 0.6±0.1%; P?=?1.0) and beta zone (8.2±0.5% versus 6.3±0.6%;P?=?1.0). Conclusions In adult Chinese in Greater Beijing, the 5-year progression rate of beta zone of parapapillary atrophy (seen in 8.2±0.5% of subjects) was significantly correlated with higher age, rural region of habitation, absence of arterial hypertension, higher intraocular pressure, higher myopic refractive error, thicker central corneal thickness, and presence of glaucoma. It was not associated with non-glaucomatous optic nerve damage.

Guo, Yin; Wang, Ya Xing; Xu, Liang; Jonas, Jost B.

2012-01-01

398

A 10-year follow up of reproductive function in women treated for childhood cancer.  

PubMed

Previously, this study group found that female childhood cancer survivors could be at risk of early cessation of fertility. The aim of the present study was to evaluate reproductive function in the same group of survivors 10 years after the initial study. Of the original cohort of 100, 71 were re-examined. Thirty-six survivors reported regular menstrual cycles. When they were compared with 210 controls, they differed significantly in antral follicle count (AFC) (median 15 versus 18, P=0.047) but not in anti-Müllerian hormone (AMH) (median 13.0 versus 17.8 pmol/l). Survivors cured with minimal gonadotoxic treatment had significantly higher AMH and AFC compared with survivors cured with either potentially gonadotoxic treatment or treatment including alkylating chemotherapy and ovarian irradiation (20.0, 5.8 and <3 pmol/l, P<0.001; and 15, 9 and 2, P=0.03, respectively). Thirty-eight survivors had achieved at least one live birth. Complicated second-trimester abortions (n=4) were observed primarily in survivors cured with radiotherapy affecting pelvic organs. In conclusion, childhood cancer survivors have signs of diminished ovarian reserve. However, if the ovarian function is preserved in the early to mid-twenties, it is likely to persist until the mid-thirties, giving a good chance of childbearing. PMID:23768622

Nielsen, S N; Andersen, A N; Schmidt, K T; Rechnitzer, C; Schmiegelow, K; Bentzen, J G; Larsen, E C

2013-08-01

399

Health conditions of bus drivers in a 6 year follow up study.  

PubMed

The bus drivers of a public bus company, working in a fast rotating 4 shift system from 05.00 to 24.30, were examined in 1993 (230 persons) and 1999 (266 persons). The comparison between the two years showed no significant differences for all the parameters evaluated by the Standard Shiftwork Index and medical examination. In both surveys work organisation was considered "efficient-fairly good" by most workers, who were mostly satisfied with their job. Work load was rated significantly higher for "afternoon" and "morning" shifts, during which most accidents at work and "in itinere" occurred. Night sleep was reduced by 3 hours on "early" shift and about 2 hours on "morning" shifts. The most prevalent health troubles dealt with low back pain, gastritis, headache and haemorrhoids. Neuroticism was the trait more correlated with poorer health conditions, whereas shiftwork exposure appeared as a significant predictor of risk of critical Effort/Reward Imbalance and minor psychological disorders. Both extrinsic and intrinsic efforts significantly increased with age, but not reward. The comparison of the same cohort of 108 persons examined both in 1993 and in 1999 showed a significant increase of low back pain, gastrointestinal troubles, haemorrhoids and lipids disorders. PMID:14564916

Costa, G; Sartori, S; Facco, P; Apostoli, P

2001-12-01

400

Gastritis cystica profunda recurrence after surgical resection: 2-year follow-up  

PubMed Central

Background Gastritis cystica profunda (GCP) is an uncommon disease characterized by multiple cystic gastric glands within the submucosa of the stomach. Case description Here, we present a case of a 63-year-old man with intermittent epigastric discomfort in whom gastroscopy revealed multiple irregular elevated nodular lesions with smooth surfaces at the anterior of the antrum. Surgical resection of the nodular lesions was performed, and the diagnosis of gastritis cystica profunda (GCP) was confirmed by histological examination. Another elevated nodular lesion approximately 10 mm in diameter with an ulcer was found on the gastric side of the remnant stomach near the resection side from 6 to 24 months after the surgical resection. Endoscopic ultrasonography (EUS) and repeated biopsies of the new elevated lesion were performed. Homogeneous, anechoic masses originating from the submucosa without gastric adenocarcinoma in histological examination showed GCP recurrence may occur. Conclusions We report a case of GCP recurrence within 6 months after surgical resection. GCP should be considered in the differential diagnosis of elevated lesions in the stomach.

2014-01-01

401

First hip arthroplasty register in Italy: 55,000 cases and 7 year follow-up  

PubMed Central

The Register for Orthopaedic Prosthetic Implantation (RIPO) has been prospectively collecting data on hip prostheses performed in all the orthopaedic units in the region Emilia-Romagna since January 2000. The register aims to determine the characteristics of patients, evaluate the effectiveness of prostheses, and allow internal audit. Adherence to the register is compulsory (93% capture). By 31 December 2006 the register contained data on 35,041 primary total hip arthroplasty (THA), 14,613 hemiarthoplasties, and 5,878 revisions. All prosthetic components are registered on an individual basis. Survival analysis is done following the Kaplan Meier method. Cumulative survival rate at 7 years is 96.8% (95% CI: 96.4–97.1%) for THA and 97.6% (97.0–98.3%) for hemiarthroplasties. Multivariate analysis verified that survival of the THA is affected by pathology, where the worst conditions are rheumatoid arthritis, femoral neck fracture, and sequelae of coxitis or Paget’s disease. Results are comparable to other major registers of Northern Europe and Australia.

Bordini, B.; De Clerico, M.; Petropulacos, K.; Toni, A.

2007-01-01

402

A five-year follow-up of patients with borderline pathology of childhood.  

PubMed

Borderline pathology of childhood (BPC) may be a precursor of personality disorders. There is a lack of data concerning outcome in adolescence. A group of 59 adolescents, who had been treated as children in a Child Psychiatry Day Hospital five to seven years earlier, was evaluated. Using the child version of the Retrospective Diagnostic Interview for Borderlines, 28 participants had been diagnosed with BPC while the remaining 31 participants who did not have a history of BPC served as the comparison group. The youth and their parents were given a battery of measures assessing current psychopathology and functional status. The group with a history of BPC was more likely than the comparison group to exhibit a combination of internalizing and externalizing behavior problems. Adolescents with a history of BPC were more impaired than the comparison group on a global measure of functional status. Compared to children with no history of BPC, children diagnosed with BPC are more likely to display poorer functioning as adolescents and continue to be at risk for psychopathology during adolescence. Future directions for research are discussed. PMID:18072867

Zelkowitz, Phyllis; Paris, Joel; Guzder, Jaswant; Feldman, Ronald; Roy, Carmella; Rosval, Lindsay

2007-12-01

403

Surgical management of closed tibiotalar dislocation: a case report and 2-year follow-up.  

PubMed

We report a case of a closed tibiotalar dislocation without an associated malleolar fracture, in the presence of medial malleolar hypoplasia, treated with closed reduction and surgical repair of the deltoid ligament, followed by cast immobilization. Post-reduction radiographs, before open repair of the deltoid ligament, revealed an Elisé test ratio of 0.43. The ruptured superficial and deep portions of the deltoid ligament and the anterior ankle capsule were primarily repaired with suture, after which cast immobilization and non-weight bearing were used before physiotherapy and rehabilitation. Two years after the injury, the patient was pain free with a full range of ankle motion, and there were no signs of residual instability or early osteoarthritis. Subjective clinical testing using a valid health measurement instrument revealed an excellent clinical outcome. Based on our experience in this case, closed ankle dislocation in the presence of a hypoplastic medial malleolus and stress manipulation evidence of medial instability indicates the need for primary repair of the deltoid ligament. Level of Clinical Evidence: 4. PMID:19857828

Fotiadis, Elias; Kenanidis, Eustathios; Hytas, Anastasios; Lyrtzis, Christos; Koimtzis, Miltiadis; Akritopoulou, Kiriaki; Samoladas, Efthimios

2009-01-01

404

Twelve years of follow up of cases with old 241Am internal contamination.  

PubMed

A group of workers internally contaminated with Am have been followed for about 12 years. The source of contamination was AmO2 powder used for production of AmBe neutron sources and other applications. The production of some radionuclide sources included chemical treatment of the original material, which transformed the americium into the nitrate, but mostly powder metallurgy was used for production of sources for smoke detectors. In vivo measurement of the workers was performed with two LEGe detectors placed near the head of the measured person. Calibration was performed with four different physical skull phantoms of different origin and a voxel phantom with Monte Carlo simulation, which was developed to fit the head sizes of individual persons. Samples of urine and feces were analyzed by means of radiochemical separation followed by alpha-spectrometry. Separation of 241Am from mineralized excreta was performed by combined anion exchange and extraction chromatographic techniques. As a tracer, 243Am was used. When the measured data (83 data on skeletal activity, activity in 389 bioassay samples) were compared with International Commission on Radiological Protection's and Leggett's biokinetic models of americium, it was found that in most cases, after more than 15 y since the intake, the excretion rate was lower (or skeletal activity higher) than predicted. On the other hand, the ratio of excreted activity in urine and feces agrees well with model predictions. PMID:20838090

Malátová, Irena; Vrba, Tomás; Becková, Vera; Pospísilová, Helena

2010-10-01

405

Balloon dilatation of unoperated aortic coarctation: immediate results and one year follow up.  

PubMed Central

Fifteen patients aged 1-19 years (mean 10.9) with previously unoperated aortic coarctation underwent percutaneous balloon angioplasty between January 1985 and February 1986. Nine (60%) were hypertensive at presentation. Under general anaesthetic the systolic coarctation gradient was 24-50 mm Hg (mean 29) and the coarctation diameter was 4-9 mm (mean 5.5). Meditech balloon catheters 8-18 mm in diameter were inflated 1-4 times at 410-760 kPa. After dilatation the systolic coarctation gradient decreased to 0-20 mm Hg (mean 6) and the coarctation diameter increased to 7-20 mm (mean 12). One patient developed a fusiform aneurysm of the aorta at the coarctation site immediately after the procedure. At reinvestigation 6-16 months (mean 12.5) after dilatation 14 of the 15 patients were normotensive. In 13 patients the residual coarctation gradient was 0-10 mm Hg (mean 3). Two patients had recoarctation with residual gradients of 20 and 24 mm Hg and underwent successful repeat dilatation. One patient had developed a small discrete aneurysm at the coarctation site. Balloon angioplasty is thus a safe and effective method of relieving unoperated aortic coarctation. The frequency of aortic aneurysm and recoarctation is small and probably related to balloon size. This early experience is encouraging, but long term results and further experience are required before this approach is used to treat coarctation generally. Images Fig 3 Fig 4 Fig 5

Wren, C; Peart, I; Bain, H; Hunter, S

1987-01-01

406

The First Two Years of Electromagnetic Follow-Up with Advanced LIGO and Virgo  

NASA Astrophysics Data System (ADS)

We anticipate the first direct detections of gravitational waves with Advanced LIGO and Virgo later this decade. Though this groundbreaking technical achievement will be its own reward, a still greater prize could be observations of compact binary mergers in both gravitational and electromagnetic channels simultaneously. During Advanced LIGO and Virgo's first two years of operation, 2015 through 2016, we expect the global gravitational-wave detector array to improve in sensitivity and livetime and expand from two to three detectors. We model the detection rate and the sky localization accuracy for binary neutron star mergers across this transition. We have analyzed a large, astrophysically motivated source population using real-time detection and sky localization codes and higher-latency parameter estimation codes that have been expressly built for operation in the Advanced LIGO/Virgo era. We show that for most binary neutron star events the rapid sky localization, available about a minute after a detection, is as accurate as the full parameter estimation. We demonstrate that Advanced Virgo will play an important role in sky localization, even though it is anticipated to come online with only 1/3 as much sensitivity as the Advanced LIGO detectors. We find that the median 90% confidence region shrinks from ~500 square degrees in 2015 to ~200 square degrees in 2016. From hundreds of simulated events unfold some likely detection scenarios.

Farr, Benjamin F.; Singer, Leo; Price, Larry; Urban, Alex; Pankow, Chris; Vitale, Salvatore; Veitch, John; Farr, Will; Hanna, Chad; Cannon, Kipp; Downes, Tom; Graff, Philip; Haster, Carl-Johan; Mandel, Ilya; Sidery, Trevor; Vecchio, Alberto

2014-08-01

407

Emerging pathogens in cystic fibrosis: ten years of follow-up in a cohort of patients.  

PubMed

In patients with cystic fibrosis (CF), there is an increasing incidence of some uncommon respiratory pathogens, such as Burkholderia cepacia complex (Bcc), Stenotrophomonas maltophilia, and Achromobacter xylosoxidans. In order to evaluate the prevalence and the clinical impact of these pathogens, we retrospectively studied a total of 109 patients followed in our center from 1996 to 2006 and reviewed the results of 1,550 sputum samples. The isolation of Pseudomonas aeruginosa slightly decreased over the observed decade, whereas Staphylococcus aureus exhibited an irregular trend. Infection with Bcc reached a peak in 1998 and successively decreased to a stable 4%. S. maltophilia and A. xylosoxidans were the real emerging pathogens, since first isolation occurred in 2004; however, the percentage of infected patients remained low (7% and 3.2%, respectively) through the years. In conclusion, in our center for CF, the reduced prevalence of P. aeruginosa over the last decade has been associated with a concurrent reduction of infections by Bcc and, as compared to other centers in Italy, Europe, and the US, with a low incidence of emerging pathogens such as S. maltophilia and A. xylosoxidans. PMID:18758832

Spicuzza, L; Sciuto, C; Vitaliti, G; Di Dio, G; Leonardi, S; La Rosa, M

2009-02-01

408

Work-related burn injuries in Ontario, Canada: A follow-up 10-year retrospective study.  

PubMed

Work-related burn injuries contribute to a quarter of all burns in the USA. In 2009, the provincial Workplace Safety and Insurance Board reported 64,824 work-related injuries that resulted in time lost, 1188 injuries (2%) were a result of burns. There were two previous studies performed at a regional burn centre (1984-1990 and 1998-2000) that examined incidence and characteristics of work-related burns. There was no significant change between these two groups. The purpose of this study was to identify the recent pattern of work-related burns from 2001 to 2010 and to compare it to the previous studies. During the study period, 1427 patients were admitted for an acute injury to the regional burn centre. Of these, 330 were due to a work-related incident (23%). The mean age of patients was 40.5±11.9 years, 95% were male. The mean total body surface area burn was 11.9±16.2%. The most common mechanism of injury was flame (32.7%) followed by electrical (27%) and scald (19.7%), inhalation injury was present in 4.8% of patients and the mortality was 1.8%. Our study shows a significant decrease in the incidence in work-related burns treated at the regional burn centre (23.1% vs. 28.2% vs. 30.2%, p<0.01), flame burns have now become the leading cause of injury, there was a significant reduction in inhalation injury (4.8% vs. 23% vs. 14.8%, p<0.00001), and mortality over time (1.8% vs. 4% vs. 6.7% p=0.02). These findings strongly suggest a change in the cause of work-related burns, improvement in burn care, and that prevention strategies may have been more effective. PMID:23352030

Clouatre, Elsa; Gomez, Manuel; Banfield, Joanne M; Jeschke, Marc G

2013-09-01

409

Eighteen-year follow-up after rotationplasty for a grade IIIC open fracture of the distal femur.  

PubMed

We report the 18-year follow-up of a patient who underwent rotationplasty for severe bone loss and infection after an grade IIIC open fracture of the distal femur. The patient is now 49 years old and fully satisfied with his life. During the follow-up period, he has never had significant physical or psychological problems directly concerning the rotationplasty. The analysis of quality of life using the SF36 questionnaire revealed even higher scores than the normal healthy population in seven out of eight sub-categories. Clinical examination revealed bland soft tissues without hyperkeratosis or other signs of maladaptation. Articular and cutaneous proprioception was intact all over the left leg. The active extension/flexion of the prosthetic knee was 0°-0°-100° and 10°-0°-70° of the ankle joint. Manual testing of motor strength revealed grade five of five for dorsiflexion and plantar flexion of the ankle. Gait patterns including climbing slopes and stairs were close to normal. Examination in sports physiology showed lower maximum power of hip and knee muscles compared to the healthy side, but better muscular endurance. These findings emphasize that rotationplasty can be a good alternative to arthrodesis or amputation in trauma patients providing high satisfaction and activity levels in the long-term follow-up. PMID:23266823

Petri, M; Omar, M; Horstmann, H; Brand, S; Krettek, C

2013-03-01

410

The course of dysphoric affective and cognitive states in borderline personality disorder: a 10-year follow-up study  

PubMed Central

The current study aimed to assess dysphoric states among 290 patients with borderline personality disorder (BPD) and 72 non-borderline axis II comparison subjects (OPD) over a 10-year course of prospective follow-up. Additionally, we assessed the severity of these states among borderline patients who had and had not recovered both symptomatically and psychosocially. The Dysphoric Affect Scale (DAS) – a 50-item self-report measure of affective and cognitive states thought to be common among borderline patients and specific to the disorder – was administered at five waves of prospective follow-up. Affective and cognitive DAS items were separately analyzed, yielding respective subscores. Borderline patients reported more severe dysphoric states compared to OPD subjects at baseline. However, the severity of affective and cognitive states declined significantly for both groups taken together over 10–years of follow-up. Within the BPD group, recovered subjects reported less severe dysphoric states compared to non-recovered subjects at baseline. Results also showed a significant decline in DAS scores over time, but at a greater rate for recovered subjects. In sum, while the severity of dysphoric states declines significantly over time, inner distress remains an area of vulnerability for borderline subjects. Additionally, the severity and pervasiveness of these states may affect recovery over time.

Reed, Lawrence Ian; Fitzmaurice, Garrett; Zanarini, Mary C.

2011-01-01