Science.gov

Sample records for 2006-2015 plano decenal

  1. Starspots on LO Pegasi, 2006-2015

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Chalmers, Mark; Geda, Robel; Henry, Brandi; Sliupas, Viesulas

    2016-01-01

    LO Pegasi is a rapidly rotating (P = 10.154 hr) young solar analog (spectral class K5-7V) variable star of BY Dra type that exhibits dark starspots on its surface that modulate its brightness as they are carried into and out of view by the star's rotation. Surface maps of the spot distribution were produced based on BVRI photometry obtained at Perkins Observatory from 2006-2015. The maps were generated from the light curves via a non-linear inversion algorithm that uses the differences in the limb darkening through different filter passbands to improve the latitude resolution of the maps. We present an analysis of variations in the size of a polar spot suggested by changes in the average brightness and the amplitude of the rotational modulation from year to year.

  2. 40 CFR 721.10094 - Decene, branched and linear.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Decene, branched and linear. 721.10094... Substances § 721.10094 Decene, branched and linear. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as decene, branched and linear (PMN P-03-272;...

  3. CALIPSO Polar Stratospheric Cloud Observations from 2006-2015

    NASA Technical Reports Server (NTRS)

    Pitts, Michael C.; Poole, Lamont R.

    2015-01-01

    record from 2006- 2015.

  4. CALIPSO Polar Stratospheric Cloud Observations from 2006-2015

    NASA Astrophysics Data System (ADS)

    Pitts, Michael; Poole, Lamont

    2015-04-01

    -year data record from 2006-2015.

  5. Growth characteristic, guest distribution, guest ordering and the stability of urea inclusion compounds with 1-decene, n-decane and mixture of 1-decene and n-decane

    NASA Astrophysics Data System (ADS)

    Wang, Yan; Ge, Xihui; Zhang, Minqing; Zhu, Huaigong; Zhang, Zijian; Wang, Ming

    2014-01-01

    Growth characteristics of urea inclusion compounds with 1-decene, n-decane and mixture of 1-decene and n-decane (relative mass ratio = 1:1) were studied by CCD high-speed Camera. The present studies show that the speed of UICs growth in tunnel direction is faster than in vertical direction and the length of UICs with 1-decene is shorter than UICs with n-decane, and the length of UICs with mixture is between them due to the influence of the vinyl in 1-decene. The value of R = I(CH2)/I(CH3) and M = I(CHCH2)/I(CH3) in FTIR spectrum of UICs increasing with growth time demonstrates that urea prefers to include n-decane than 1-decene. 13C CP/MAS NMR studies of UICs indicate that the arrangement of 1-decene in UICs is CH3⋯CH3 and CHCH2⋯CH2CH. The arrangement of 1-decene in UICs leads to short chain of UICs with 1-decene in tunnel direction. The 13C CP/MAS NMR spectra of UICs with MIX reveal that there are three different types of arrangement: CH3⋯CH3, CHCH2⋯CH3 and CHCH2⋯CH2CH. The methods of FTIR and DSC were used to test the stability of UICs with different guests. The result shows that UICs with n-decane are stable than UICs with 1-decene. And the stability of UICs with mixture is in the middle.

  6. 78 FR 3415 - 3-Decen-2-One; Receipt of Application for Emergency Exemption, Solicitation of Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... pesticide 3-decen-2-one (CAS No. 10519-33-2) to treat up to 500,000 tons of potatoes with 3-decen-2-one to burn-off potato sprouts in storage facilities. The applicant proposes the use of a new chemical which... exemption for the use of 3-decen-2- one on potatoes in storage facilities to burn off already...

  7. 78 FR 11760 - 3-decen-2-one; Exemption from the Requirement of a Tolerance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ...This regulation establishes an exemption from the requirement of a tolerance for residues of the biochemical pesticide, 3-decen-2- one, in or on potatoes when applied as a postharvest potato sprout inhibitor and used in accordance with label directions and good agricultural practices. On behalf of AMVAC Chemical Corporation (AMVAC), Technology Sciences Group, Inc. (TSG) submitted a petition to......

  8. Volcano and Earthquake Monitoring Plan for the Yellowstone Volcano Observatory, 2006-2015

    USGS Publications Warehouse

    Yellowstone Volcano Observatory

    2006-01-01

    To provide Yellowstone National Park (YNP) and its surrounding communities with a modern, comprehensive system for volcano and earthquake monitoring, the Yellowstone Volcano Observatory (YVO) has developed a monitoring plan for the period 2006-2015. Such a plan is needed so that YVO can provide timely information during seismic, volcanic, and hydrothermal crises and can anticipate hazardous events before they occur. The monitoring network will also provide high-quality data for scientific study and interpretation of one of the largest active volcanic systems in the world. Among the needs of the observatory are to upgrade its seismograph network to modern standards and to add five new seismograph stations in areas of the park that currently lack adequate station density. In cooperation with the National Science Foundation (NSF) and its Plate Boundary Observatory Program (PBO), YVO seeks to install five borehole strainmeters and two tiltmeters to measure crustal movements. The boreholes would be located in developed areas close to existing infrastructure and away from sensitive geothermal features. In conjunction with the park's geothermal monitoring program, installation of new stream gages, and gas-measuring instruments will allow YVO to compare geophysical phenomena, such as earthquakes and ground motions, to hydrothermal events, such as anomalous water and gas discharge. In addition, YVO seeks to characterize the behavior of geyser basins, both to detect any precursors to hydrothermal explosions and to monitor earthquakes related to fluid movements that are difficult to detect with the current monitoring system. Finally, a monitoring network consists not solely of instruments, but requires also a secure system for real-time transmission of data. The current telemetry system is vulnerable to failures that could jeopardize data transmission out of Yellowstone. Future advances in monitoring technologies must be accompanied by improvements in the infrastructure for

  9. MOLECULAR SPECIATION OF SECONDARY ORGANIC AEROSOL FROM PHOTOOXIDATION OF THE HIGHER ALKENES: 1-OCTENE AND 1-DECENE. (R824970)

    EPA Science Inventory

    Outdoor smog chamber photooxidations to determine the molecular composition of secondary organic aerosol (SOA) from 1-octene and 1-decene in sunlight-irradiated hydrocarbon-NOx mixtures are reported. The observed products are consistent with the current under...

  10. Nematicidal activity of (E,E)-2,4-decadienal and (E)-2-decenal from Ailanthus altissima against Meloidogyne javanica.

    PubMed

    Caboni, Pierluigi; Ntalli, Nikoletta G; Aissani, Nadhem; Cavoski, Ivana; Angioni, Alberto

    2012-02-01

    Methanol extracts of various plant parts of Ailanthus altissima were tested against the root knot nematode Meloidogyne javanica . Extracts of bark (ABE), wood (AWE), roots (ARE), and leaves (ALE) from A. altissima were investigated against freshly hatched second-stage juveniles (J(2)). AWE was the most active extract, with EC(50/3d) of 58.9 mg/L, while ALE, ARE, and ABE did not show nematicidal activity. The chemical composition of the extracts of A. altissima was determined by gas chromatography-mass spectrometry, and (E,E)-2,4-decadienal, (E)-2-undecenal, (E)-2-decenal, hexanal, nonanal, and furfural were the most prominent constituents. (E,E)-2,4-Decadienal, (E)-2-decenal, and furfural showed the highest nematicidal activity against M. javanica , with EC(50/1d) = 11.7, 20.43, and 21.79 mg/L, respectively, while the other compounds were inactive at the concentrations tested. The results obtained showed that AWE and its constituents (E,E)-2,4-decadienal and (E)-2-decenal could be considered as potent botanical nematicidal agents. PMID:22224661

  11. Environmental Studies. Plano Outdoor Learning Center.

    ERIC Educational Resources Information Center

    Plano Independent School District, TX.

    This curriculum guide for the Plano Intermediate School District (Texas) Outdoor Learning Center is divided into three major sections. Section I provides information on the numbered stations/posts found along the perimeter and inner trails of the center and includes brief comments on the philosophy of environmental education and the history…

  12. Noncatalytic hydrogenation of decene-1 with hydrogen accumulated in a hybrid carbon nanostructure in nanosized membrane reactors

    NASA Astrophysics Data System (ADS)

    Soldatov, A. P.

    2014-08-01

    Studies on the creation of nanosized membrane reactors (NMRs) of a new generation with accumulated hydrogen and a regulated volume of reaction zone were continued at the next stage. Hydrogenation was performed in the pores of ceramic membranes with hydrogen preliminarily adsorbed in mono- and multilayered orientated carbon nanotubes with graphene walls (OCNTGs)—a new hybrid carbon nanostructure formed on the inner pore surface. Quantitative determination of hydrogen adsorption in OCNTGs was performed using TRUMEM ultrafiltration membranes with D av = 50 and 90 nm and showed that hydrogen adsorption was up to ˜1.5% of the mass of OCNTG. The instrumentation and procedure for noncatalytic hydrogenation of decene-1 at 250-350°C using hydrogen accumulated and stored in OCNTG were developed. The conversion of decene-1 into decane was ˜0.2-1.8% at hydrogenation temperatures of 250 and 350°C, respectively. The rate constants and activation energy of hydrogenation were determined. The latter was found to be 94.5 kJ/mol, which is much smaller than the values typical for noncatalytic hydrogenations and very close to the values characteristic for catalytic reactions. The quantitative distribution of the reacting compounds in each pore regarded as a nanosized membrane reactor was determined. The activity of hydrogen adsorbed in a 2D carbon nanostructure was evaluated. Possible mechanisms of noncatalytic hydrogenation were discussed.

  13. Dynamic Modeling of Hydro- Formylation of 1-Decene on Rh/C Catalyst in Bubble Column Slurry Reactor

    NASA Astrophysics Data System (ADS)

    Upkare, Makarand M.; Rajurkar, Kalpendra B.; Das, Samir K.; Jaganathan, R.

    2010-10-01

    A dynamic model has been developed for the bubble column slurry reactor operating under non-isothermal conditions. The model consists of mass and heat balance equations for the gas and liquid phases and the catalyst particle. The model equations consisted of partial differential equations (PDE) which were converted to ordinary differential equations (ODE) by using finite difference relationships for the spatial derivatives and the ordinary differential equations for the time derivatives (Numerical Method of Lines-NMoL). The model was applied to describe the dynamic behaviour of bubble column slurry reactor during the hydroformylation of 1-decene on Rh/C catalyst. Model simulations were performed to obtain a meaningful path to steady state and to reproduce the other characteristics of the dynamic behaviour of the reactor. Under given conditions, the reaction required approximately 3750 seconds to reach the steady state concentrations at various reactor positions. It was observed with increase in the fluid velocities, the dynamics of the system was altered to 2500 seconds to reach the steady state condition. The effect of axial dispersion on the substrate concentration and the temperature rise along the reactor was further studied and discussed.

  14. DDT and pyrethroid resistance status and laboratory evaluation of bio-efficacy of long lasting insecticide treated nets against Culex quinquefasciatus and Culex decens in Ghana.

    PubMed

    Kudom, Andreas A; Mensah, Ben A; Froeschl, Guenter; Rinder, Heinz; Boakye, Daniel

    2015-10-01

    Nuisance from Culex mosquitoes in Ghana has a serious negative impact on the standard of living in many urban communities. In addition, a perceived lack of efficacy of long lasting insecticide treated nets (LLINs) against nuisance mosquitoes contributes to their discontinued use. This again compromises malaria control, even if Anopheles species themselves would still be susceptible to the insecticides used. Control strategies involve pyrethroid insecticides but information on Culex mosquito susceptibility to these insecticides is limited. A nationwide survey was conducted to address this problem. In adults, susceptibility to permethrin, deltamethrin and DDT as well as enzyme activity and kdr mutation were determined. Cone and tunnel bioassay were also carried out to determine the efficacy of LLINs against the mosquitoes. Culex quinquefasciatus and Culex decens were identified in the study area. Higher deltamethrin and DDT resistance and relatively low permethrin resistance were observed in both species. High enzyme activities and kdr mutations were observed in C. quinquefasciatus but not in C. decens. However, reduced efficacy of LLINs was observed in both mosquito species. This adds up to the evidence of the spread of pyrethroid resistance in mosquitoes and its negative impact on control strategies. PMID:26215129

  15. Reinterpretation of the Robein and Plano Silts, northeastern Illinois

    SciTech Connect

    Curry, B.B.; Kempton, J.P.

    1985-01-01

    Reinterpretation of till stratigraphy in northern Illinois and recently obtained radiocarbon dates suggest the Plano Silt is lithologically and stratigraphically indistinguishable from the Robein Silt. These recent data suggest colluvial silt and organic-rich sediment were deposited in most of the northern Illinois between >50,000 and 23,000 RCBP. This age range agrees with radiocarbon dates from the Mid-Wisconsinan Sidney Interstadial Soil of the Huron-Erie Lobe. Altonian (Early to Mid-Wisconsinan)-age till associated with the Lake Michigan Lobe has not yet been identified. Horberg and others recognize in northeastern Illinois a single basal Wisconsinan organic-rich zone; peat, silt and loess of the Farmdalian Substage were interpreted to overlie Sangamon Soil developed in Illinoian drift. They also interpreted a reddish-brown diamicton overlying the Plano Silt at its type section as the Capron Till Member of late Altonian age. The new data support the earlier interpretation of a single organic-rich deposit between Wisconsinan and Illinoian drifts. The Plano Silt should be abandoned as a rock-stratigraphic unit. The Robein Silt includes colluvium and organic-rich sediment not only of Farmdalian age, but also Altonian age in most of northern Illinois, similar to the rest of the upper Mississippi River Valley. The evidence of nearly continuous Robein deposition restricts possible Altonian-age glacial deposits to a narrow band on Capron Ridge in northern Illinois and southern Wisconsin.

  16. Studies on the aroma of five fresh tomato cultivars and the precursors of cis- and trans-4,5-epoxy-(E)-2-decenals and methional.

    PubMed

    Mayer, Florian; Takeoka, Gary R; Buttery, Ron G; Whitehand, Linda C; Naim, Michael; Rabinowitch, Haim D

    2008-05-28

    Three tasty (BR-139, FA-624, and FA-612) and two less tasty (R-144 and R-175) fresh greenhouse tomato cultivars, which significantly differ in their flavor profiles, were screened for potent odorants using aroma extract dilution analysis (AEDA). On the basis of AEDA results, 19 volatiles were selected for quantification in those 5 cultivars using gas chromatography-mass spectrometry (GC-MS). Compounds such as 1-penten-3-one, ( E, E)- and ( E, Z)-2,4-decadienal, and 4-hydroxy-2,5-dimethyl-3(2 H)-furanone (Furaneol) had higher odor units in the more preferred cultivars, whereas methional, phenylacetaldehyde, 2-phenylethanol, or 2-isobutylthiazole had higher odor units in the less preferred cultivars. Simulation of the odor of the selected tomato cultivars by preparation of aroma models and comparison with the corresponding real samples confirmed that all important fresh tomato odorants were identified, that their concentrations were determined correctly in all five cultivars, and that differences in concentration, especially of the compounds mentioned above, make it possible to distinguish between them and are responsible for the differential preference. To help elucidate formation pathways of key odorants, labeled precursors were added to tomatoes. Biogenesis of cis- and trans-4,5-epoxy-( E)-2-decenals from linoleic acid and methional from methionine was confirmed. PMID:18459793

  17. 75 FR 52065 - SharePlus Federal Bank, Plano, TX; Approval of Conversion Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Office of Thrift Supervision SharePlus Federal Bank, Plano, TX; Approval of Conversion Application Notice... SharePlus Federal Bank, Piano, Texas, to convert to the stock form of organization. Copies of...

  18. 75 FR 27119 - ViewPoint Financial Group, Inc., Plano, Texas; Approval of Conversion Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Office of Thrift Supervision ViewPoint Financial Group, Inc., Plano, Texas; Approval of Conversion Application Notice is hereby given that on May 6, 2010, the Office of Thrift Supervision approved the application of ViewPoint MHC and ViewPoint...

  19. Closed laser-beam trajectories in plano-spherical resonators with Gaussian apertures

    SciTech Connect

    Malyutin, A A

    2008-02-28

    The closed trajectories of a Gaussian beam in plano-spherical degenerate and nondegenerate resonators with two Gaussian apertures (with two pump regions with the Gaussian distribution of the gain) are described analytically and the existence conditions are found for such trajectories. It was assumed that Gaussian apertures (gain regions) were located in the plane of a flat mirror at equal distances on both sides of the resonator axis and the size of apertures restricted their action by the corresponding half-plane. (beams, resonators)

  20. Designing null phase screens to test a fast plano-convex aspheric lens

    NASA Astrophysics Data System (ADS)

    DelOlmo-Márquez, Jesús; Castán-Ricaño, Diana; Avendaño-Alejo, Maximino; Díaz-Uribe, Rufino

    2015-08-01

    We have obtained a formula to represent the wavefront produced by a plano-convex aspheric lens with symmetry of revolution considering a plane wavefront propagating parallel to the optical axis and impinging on the refracting surface, it is called a zero-distance phase front, being it the first wavefront to be out of the optical system. Using a concept of differential geometry called parallel curves it is possible to obtain an analytic formula to represent the wavefront propagated at arbitrary distances through the optical axis. In order to evaluate qualitatively a plano-convex aspheric lens, we have modified slightly an interferometer Tywman-Green as follow: In the reference beam we use a plane mirror and the beam of test we have used a spatial light modulator (SLM) to compensate the phase produced by the lens under test. It will be called a null phase interferometer. The main idea is to recombine both wavefronts in order to get a null interferogram, otherwise we will associate the patterns of the interferogram to deformations of the lens under test. The null phase screens are formed with concentric circumferences assuming different gray levels printed on SLM.

  1. Development of a large plano-elliptical neutron-focusing supermirror with metallic substrates.

    PubMed

    Takeda, Shin; Yamagata, Yutaka; Yamada, Norifumi L; Hino, Masahiro; Hosobata, Takuya; Guo, Jiang; Morita, Shin-Ya; Oda, Tatsuro; Furusaka, Michihiro

    2016-06-13

    Results of this study demonstrated that electroless nickel-phosphorus (NiP) plated metal substrate is an excellent material for producing large aspherical neutron-focusing supermirrors. A large plano-elliptical neutron-focusing supermirror comprising two metallic segments was fabricated using single-point diamond cutting, precision polishing and supermirror coating. The average surface roughness of the metallic substrates was approximately 0.3 nm rms. For evaluation, the focusing supermirror was installed at the SOFIA neutron reflectometer, showing high neutron reflectivity and giving minimal beam width of 0.34 mm in FWHM. Because of the large beam divergence accepted by the mirror, the count rate with the focusing mirror was 3.3 times higher than that obtained using conventional two-slit collimation. PMID:27410268

  2. Internal structure of an optical null Ronchi grating test for a plano-parabolic lens.

    PubMed

    Ortega-Vidals, Paula; Juárez-Reyes, Salvador Alejandro; Silva-Ortigoza, Gilberto; Cabrera-Rosas, Omar de J

    2016-01-01

    In this work we use geometrical optics and the caustic touching theorem, introduced by Berry, to describe the internal structure of the null Ronchi grating for a plano-parabolic lens illuminated by a point light source placed on the optical axis. The aim of this work is to explain the role of the caustic region in the process of morphology change between image and object in computing the null Ronchi grating. To this end, we obtain the analytic expression of the null Ronchi grating, and after that we deeply study the change in morphology between a single straight fringe image at the Ronchigram and the multiple curve rulings that can generate it (one open and one closed). We analyze exactly how multiple rulings generate the same straight image fringe, or how an entire ruling collapses into a single point image. For this analysis, we take different observation planes at different positions with respect to the caustic region. Finally, we characterize this topological change as one of two possible kinds depending on the relative position between the observation plane and the caustic region. PMID:26831584

  3. Sub-wavelength focusing of cylindrical vector beams by a 1D metallic photonic crystal plano-concave lens

    NASA Astrophysics Data System (ADS)

    Zhong, Yi; Wang, Jin; Xu, Ji

    2014-10-01

    The fine manipulations of cylindrical vector beams (CVBs) based on metallic microstructures, such as sub-wavelength focusing, have entered many interdisciplinary areas, and the important applications have been found in many fields including optical micromanipulation, super-resolution imaging, micro-machining and so on. But so far, the sub-wavelength focusing of azimuthally polarized beams is encountered, since the manipulation mechanisms rely heavily on the excitation of surface plasmon polaritons, which brings the polarization limitation. We theoretically investigated the focusing behavior of CVBs in 1D metallic photonic crystals (MPCs). The simulation results show that a 1D MPC plano-concave lens can focus cylindrical vector beams into scale of sub-wavelength. The negative refraction at the interface between the air and the 1D MPC is analyzed at the frequencies corresponding to the second photonic band, which makes the 1D MPC has the ability to focus higher Fourier components of light beams. The cylindrical plano-concave structure is constructed to focus the radially and azimuthally polarized beams simultaneously. The behavior is demonstrated by Finite Element Method (FEM). The shape of focusing field can be tailored, by changing the polarization ratio of the incident beams. In addition, the effective sub-wavelength focusing phenomenon can also be realized in variety of wave ranges, by choosing the proper materials and adjusting the parameters. We believe that it's the first time to realize the simultaneous sub-wavelength focusing of radially and azimuthally polarized beams, the application of which is quite promising in broad prospects.

  4. Design of Hartmann type null screens for testing a plano-convex aspheric lens with a CCD sensor inside the caustic.

    PubMed

    Castillo-Santiago, Gabriel; Castán-Ricaño, Diana; Avendaño-Alejo, Maximino; Castañeda, Luis; Díaz-Uribe, Rufino

    2016-08-22

    A new method to design Hartmann type null screens to test either qualitatively or quantitatively fast plano-convex aspherical lenses is presented. We design both radial and square null screens that produce arrays of circular spots uniformly distributed at predefined planes, considering that the CCD sensor is solely placed inside the caustic region. The designs of these null screens are based on knowledge of the caustic by refraction and on exact ray tracing. The null screens also serve to improve the alignment in optical systems. PMID:27557218

  5. Solar Modulation of Galactic Cosmic Rays During 2006-2015 Based on PAMELA and ARINA Data

    NASA Astrophysics Data System (ADS)

    Mayorova, M. A.; Mayorov, A. G.; Adriani, O.; Aleksandrin, S. Y.; Barbarino, G. C.; Bazilevskaya, G. A.; Bellotti, R.; Boezio, M.; Bogomolov, E. A.; Bongi, M.; Bonvicini, V.; Bottai, S.; Bruno, A.; Cafagna, F.; Campana, D.; Carbone, R.; Carlson, P.; Casolino, M.; Castellini, G.; DeDonato, C.; DeSantis, C.; DeSimone, N.; DiFelice, V.; Formato, V.; Galper, A. M.; Karelin, A. V.; Koldashov, S. V.; Koldobskiy, S.; Kvashnin, A. A.; Kvashnin, A. N.; Leonov, A.; Malakhov, V.; Marcelli, L.; Martucci, M.; Menn, W.; Merge', M.; Mikhailov, V. V.; Mocchiutti, E.; Monaco, A.; Mori, N.; Munini, R.; Naumov, P. Yu.; Osteria, G.; Palma, F.; Panico, B.; Papini, P.; Pearce, M.; Picozza, P.; Pizzolotto, C.; Ricci, M.; Ricciarini, S. B.; Sarkar, R.; Scotti, V.; Simon, M.; Sparvoli, R.; Spillantini, P.; Stozhkov, Y. I.; Vacchi, A.; Vannuccini, E.; Voronov, S. A.; Yurkin, Y. T.; Zampa, G.; Zampa, N.; Zverev, V. G.

    Solar modulation of galactic protons with energies from 50 MeV up to dozens of GeV during July 06 - February15 studied based on a data of the magnetic spectrometer PAMELA and scintillation spectrometer ARINA. This period is interesting because it covers the end of 23rdand current 24thcycles of solar activity, including the abnormally long transient period and change of the polarity of solar magnetic field.

  6. Streptococcus pyogenes Pneumonia in Adults: Clinical Presentation and Molecular Characterization of Isolates 2006-2015

    PubMed Central

    Tamayo, Esther; Montes, Milagrosa; Vicente, Diego; Pérez-Trallero, Emilio

    2016-01-01

    Introduction In the preantibiotic era Streptococcus pyogenes was a common cause of severe pneumonia but currently, except for postinfluenza complications, it is not considered a common cause of community-acquired pneumonia in adults. Aim and Material and Methods This study aimed to identify current clinical episodes of S. pyogenes pneumonia, its relationship with influenza virus circulation and the genotypes of the involved isolates during a decade in a Southern European region (Gipuzkoa, northern Spain). Molecular analysis of isolates included emm, multilocus-sequence typing, and superantigen profile determination. Results Forty episodes were detected (annual incidence 1.1 x 100,000 inhabitants, range 0.29–2.29). Thirty-seven episodes were community-acquired, 21 involved an invasive infection and 10 developed STSS. The associated mortality rate was 20%, with half of the patients dying within 24 hours after admission. Influenza coinfection was confirmed in four patients and suspected in another. The 52.5% of episodes occurred outside the influenza seasonal epidemic. The 67.5% of affected persons were elderly individuals and adults with severe comorbidities, although 13 patients had no comorbidities, 2 of them had a fatal outcome. Eleven clones were identified, the most prevalent being emm1/ST28 (43.6%) causing the most severe cases. Conclusions S. pyogenes pneumonia had a continuous presence frequently unrelated to influenza infection, being rapidly fatal even in previously healthy individuals. PMID:27027618

  7. Fabrication and evaluation of variable focus and large deformation plano-convex microlens based on non-ionic poly(vinyl chloride)/dibutyl adipate gels

    NASA Astrophysics Data System (ADS)

    Kim, Sang-Youn; Yeo, Myoung; Shin, Eun-Jae; Park, Won-Hyeong; Jang, Jong-Seok; Nam, Byeong-Uk; Bae, Jin Woo

    2015-11-01

    In this paper, we propose a variable focus microlens module based on a transparent, electroactive, and non-ionic PVC/DBA gel. A non-ionic PVC/DBA (nPVC) gel on an ITO glass was confined beneath a rigid annular electrode, and applied pressure squeezed a bulge of the nPVC gel into the annular electrode, resulting in a hemispherical plano-convex nPVC gel microlens. The proposed nPVC gel microlens was analyzed and optimized. When voltage is applied to the circular perimeter (the annular electrode) of this fabricated microlens, electrically induced creep deformation of the nPVC gel occurs, changing its optical focal length. The focal length remarkably increases from 3.8 mm up to 14.3 mm with increasing applied voltages from 300 V to 800 V. Due to its compact, transparent, and electroactive characteristics, the proposed nPVC gel microlens can be easily inserted into small consumer electronic devices, such as digital cameras, camcorders, cell phones, and other portable optical devices.

  8. Fabrication of long-focal-length plano-convex microlens array by combining the micro-milling and injection molding processes.

    PubMed

    Chen, Lei; Kirchberg, Stefan; Jiang, Bing-Yan; Xie, Lei; Jia, Yun-Long; Sun, Lei-Lei

    2014-11-01

    A uniform plano-convex spherical microlens array with a long focal length was fabricated by combining the micromilling and injection molding processes in this work. This paper presents a quantitative study of the injection molding process parameters on the uniformity of the height of the microlenses. The variation of the injection process parameters, i.e., barrel temperature, mold temperature, injection speed, and packing pressure, was found to have a significant effect on the uniformity of the height of the microlenses, especially the barrel temperature. The filling-to-packing switchover point is also critical to the uniformity of the height of the microlenses. The optimal uniformity was achieved when the polymer melts completely filled the mold cavity, or even a little excessively filled the cavity, during the filling stage. In addition, due to the filling resistance, the practical filling-to-packing switchover point can vary with the change of the filling processing conditions and lead to a non-negligible effect on the uniformity of the height of the microlenses. Furthermore, the effect of injection speed on the uniformity of the height of the microlenses was analyzed in detail. The results indicated that the effect of injection speed on the uniformity of the height of the microlenses is mainly attributed to the two functions of injection speed: transferring the filling-to-packing switchover point and affecting the distribution of residual flow stress in the polymer melt. PMID:25402902

  9. Impact of sustainable feeds on omega-3 long-chain fatty acid levels in farmed Atlantic salmon, 2006-2015.

    PubMed

    Sprague, M; Dick, J R; Tocher, D R

    2016-01-01

    As the global population and its demand for seafood increases more of our fish will come from aquaculture. Farmed Atlantic salmon are a global commodity and, as an oily fish, contain a rich source of the health promoting long-chain omega-3 fatty acids, eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids. Replacing the traditional finite marine ingredients, fishmeal and fish oil, in farmed salmon diets with sustainable alternatives of terrestrial origin, devoid of EPA and DHA, presents a significant challenge for the aquaculture industry. By comparing the fatty acid composition of over 3,000 Scottish Atlantic salmon farmed between 2006 and 2015, we find that terrestrial fatty acids have significantly increased alongside a decrease in EPA and DHA levels. Consequently, the nutritional value of the final product is compromised requiring double portion sizes, as compared to 2006, in order to satisfy recommended EPA + DHA intake levels endorsed by health advisory organisations. Nevertheless, farmed Scottish salmon still delivers more EPA + DHA than most other fish species and all terrestrial livestock. Our findings highlight the global shortfall of EPA and DHA and the implications this has for the human consumer and examines the potential of microalgae and genetically modified crops as future sources of these important fatty acids. PMID:26899924

  10. Transient accretion disc-like envelope in the symbiotic binary BF Cygni during its 2006-2015 optical outburst

    NASA Astrophysics Data System (ADS)

    Tomov, N. A.; Tomova, M. T.; Bisikalo, D. V.

    2015-09-01

    The optical light of the symbiotic binary BF Cyg during its last eruption after 2006 shows orbital variations because of an eclipse of the outbursting compact object. The first orbital minimum is deeper than the following ones. Moreover, the Balmer profiles of this system acquired additional satellite components indicating a bipolar collimated outflow at one time between the first and second orbital minima. This behaviour is interpreted in the framework of the model of a collimated stellar wind from the outbursting object. It is supposed that one extended disc-like envelope covering the accretion disc of the compact object and collimating its stellar wind forms in the period between the first and second minima. The uneclipsed part of this envelope is responsible for the decrease of the depth of the orbital minimum. The calculated U BVR_{ C}I_{ C} fluxes of this uneclipsed part are in agreement with the observed residual of the depths of the first and second orbital minima. The parameters of the envelope require that it is the main emitting region of the line Hα but the Hα profile is less determined from its rotation and mostly from other mechanisms. It is concluded that the envelope is a transient nebular region and its destruction determines the increase of the depth of the orbital minimum with fading of the optical light.

  11. Time Variations of Proton Flux in Earth Inner Radiation Belt for 2006-2015 Years based on the PAMELA and the ARINA Data

    NASA Astrophysics Data System (ADS)

    Malakhov, V. V.; Koldashov, S. V.; Mayorov, A. G.; Mayorova, M. A.; Mikhailov, V. V.; Aleksandrin, S. Yu.

    The PAMELA and the ARINA experiments are carried out aboard satellite RESURS-DK1 since 2006 up to now. Both these instruments have possibility to measure charged particles in the inner radiation belt. Combination of these two devices covers proton energy range from 30 MeV up to trapping limit (E ∽2 GeV). Continuous measurements with PAMELA and ARINA include minimum between 23rd and 24th solar cycles falling and rising phases of 23/24 solar cycles and maximum of 24th one. It is important because existing empirical radiation belt models does not intend to calculate fluxes taking into account solar activity varying, e.g. widely used AP-8 model allows to evaluate proton fluxes just in two cases: for minimum or maximum of a solar activity. In this report we present temporal profiles of proton flux in the lower edge of the inner proton radiation belt (1.12 < L < 1.20, 0.18 < B < 0.22 G) and ratio between solar minimum and maximum fluxes. Dependence of proton fluxes on degree of solar activity were studied for various phases of 23/24 solar cycle. At that it was shown that proton fluxes of energy >80MeV at the solar minimum several times greater than at the solar maximum. Maximum difference is seen on the L-shell 1.15.

  12. Studies on the Aroma of Five Fresh Tomato Cultivars and the Precursors of the cis- and trans-4,5-Epoxy-(E)-2-Decenals and Methional

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Three tasty (BR-139, FA-624 and FA-612) and two less tasty (R 144 and R 175) fresh greenhouse tomato cultivars, which significantly differ in their flavor profiles, were screened for potent odorants using aroma extract dilution analysis (AEDA). Based on AEDA results, 19 volatiles were selected for ...

  13. Biological activities of IC201 ((3S,8E)-1,3-dihydroxy-8-decen-5-one), a low molecular weight immunomodulator produced by Streptomyces.

    PubMed

    Mizutani, S; Odai, H; Masuda, T; Iijima, M; Osono, M; Hamada, M; Naganawa, H; Ishizuka, M; Takeuchi, T

    1989-06-01

    IC201 was found in cultured broth of Streptomyces cirratus as an antitumor antibiotic which was effective in retarding growth of the established solid tumor of Ehrlich carcinoma by treatment starting 8 days after tumor inoculation. It retarded growth of the established solid tumor of IMC carcinoma but had no cytotoxicity at 100 micrograms/ml. IC201 treatment kept NK cell activity of tumor-bearing mice at normal level and stimulated cytostatic activity of peritoneal macrophages. It stimulated phagocytosis of yeast and phorbol myristate acetate-elicited superoxide production by peritoneal macrophages. The addition of IC201 to P388D1 cell cultures enhanced release of interleukin 1 (IL-1) into cultured supernatant but it affected lipopolysaccharide-induced IL-1 production. Although the addition to macrophage-depleted cultures did not show any stimulatory effect, mixed lymphocyte culture reaction was augmented in cultures using spleen cells as stimulator cells taken from mice given IC201. Results indicate that IC201 primarily activates macrophages and the activation may cause modulation of immune responses. PMID:2786863

  14. 21 CFR 172.515 - Synthetic flavoring substances and adjuvants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... dimethyl acetal. 1-Decanol; decylic alcohol. 2-Decenal. 3-Decen-2-one; heptylidene acetone. Decyl actate...; 1,3,3-trimethyl-2-norbornanol. Formic acid (2-Furyl)-2-propanone; furyl acetone. 1-Furyl-2-propanone; furyl acetone. Fusel oil, refined (mixed amyl alcohols). Geranyl acetoacetate; trans-3,7-dimethyl-2,...

  15. 21 CFR 172.515 - Synthetic flavoring substances and adjuvants.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... dimethyl acetal. 1-Decanol; decylic alcohol. 2-Decenal. 3-Decen-2-one; heptylidene acetone. Decyl actate...; 1,3,3-trimethyl-2-norbornanol. Formic acid (2-Furyl)-2-propanone; furyl acetone. 1-Furyl-2-propanone; furyl acetone. Fusel oil, refined (mixed amyl alcohols). Geranyl acetoacetate; trans-3,7-dimethyl-2,...

  16. EVALUATION OF PLANT ESSENTIAL OILS AS NATURAL POSTHARVEST DISEASE CONTROL OF TOMATO (LYCOPERSICON ESCULENTUM)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Essential oils with fungicidal activities were identified in vitro; these were oregano, thyme, lemongrass, and cilantro. Essential oil components in those plants with antimicrobial activity were carvacrol, thymol, citral, and trans-2-decenal, respectively. Vapors of thyme, oregano and lemongrass, ...

  17. Structural Effects of Biodiesel on Soot Volume Fraction in a Laminar Co-Flow Diffusion Flame

    NASA Astrophysics Data System (ADS)

    Weingarten, Jason

    An experimental study was performed to determine the structural effects of biodiesel on soot volume fraction in a laminar co-flow diffusion flame. These include the effects of the ester function group, the inclusion of a double bond, and its positional effect. The soot volume fraction and temperature profiles of a biodiesel surrogate, n-Decane, 1-Decene, and 5-Decene fuels were measured. Improvements were made to existing laser extinction and rapid thermocouple insertion apparatus and were used to measure soot volume fraction and temperature profiles respectively. Flow rates of each fuel were determined in order to keep the temperature effects on soot negligible. Using n-Decane as a baseline, the double bond increased soot production and was further increased with a more centrally located double bond. The ester function group containing oxygen decreased soot production. The order of most to least sooting fuels were as follows 5-Decene > 1-Decene > n-Decane > Biodiesel Surrogate.

  18. Mi Quinto Libro de Maquinas Simples: El Plano Inclinado. Escuela Intermedia Grados 7, 8 y 9 (My Fifth Book of Simple Machines: The Inclined Plane. Intermediate School Grades 7, 8, and 9).

    ERIC Educational Resources Information Center

    Alvarado, Patricio R.; Montalvo, Luis

    This is the fifth book in a five-book physical science series on simple machines. The books are designed for Spanish-speaking junior high school students. This volume explains the principles and some of the uses of inclined planes, as they appear in simple machines, by suggesting experiments and posing questions concerning drawings in the book…

  19. Governance Challenges in the Initiatives for Out-of-School Children in Tajikistan

    ERIC Educational Resources Information Center

    Lo, William Yat Wai; Maclean, Rupert

    2015-01-01

    This article discusses the initiatives for out-of-school children in Tajikistan. The Tajik government has published two blueprint documents, namely, the "National Strategy for Education Development 2006-2015" and the "National Strategy for Education Development until 2020," which outlines a national vision for universal access…

  20. Looking Forward with LIFE: Literacy Initiative for Empowerment. Global LIFE Mid-Term Evaluation Report 2006-2011

    ERIC Educational Resources Information Center

    Hanemann, Ulrike

    2012-01-01

    The United Nations Educational, Scientific and Cultural Organization (UNESCO) launched the Literacy Initiative for Empowerment (2006-2015)--LIFE--to tackle the literacy challenge. This is a collaborative effort to accelerate literacy efforts in thirty five of the world's most challenged countries and thereby to unlock progress to reach all of the…

  1. Advancing Literacy: A Review of LIFE 2006-2009

    ERIC Educational Resources Information Center

    Hanemann, Ulrike

    2009-01-01

    When it became clear that existing literacy efforts would not be enough to enable some countries to reach Education for All (EFA) Goal 4 (a 50 percent improvement in levels of adult literacy), UNESCO launched the Literacy Initiative for Empowerment (LIFE, 2006-2015). 35 countries with literacy rates below 50 percent and/or a population of more…

  2. 76 FR 29797 - Westpoint Home, Inc., New York Corporate Sales Office, New York, NY, Including Employees Working...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ... 7, 2010 (75 FR 39048). At the request of the State of New York, the Department reviewed the... Employment and Training Administration Westpoint Home, Inc., New York Corporate Sales Office, New York, NY... Home, Inc., Plano, TX Sales Office, Plano, TX; Westpoint Home, Inc., Daleville, IN Sales...

  3. 40 CFR 52.378 - Control strategy: PM10.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... maintenance plan (2006-2015). The State of Connecticut has committed to: maintain a PM10 monitoring network in... in the event the PM10 design value in the maintenance area exceeds 98 µgm/m3 for the 24-hour PM10... on maintaining levels of ambient PM10 below a PM10 design value criteria of 98 µgm/m3 for the...

  4. 40 CFR 52.378 - Control strategy: PM10.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... maintenance plan (2006-2015). The State of Connecticut has committed to: maintain a PM10 monitoring network in... in the event the PM10 design value in the maintenance area exceeds 98 µgm/m3 for the 24-hour PM10... on maintaining levels of ambient PM10 below a PM10 design value criteria of 98 µgm/m3 for the...

  5. Behavioral responses to mammalian blood odor and a blood odor component in four species of large carnivores.

    PubMed

    Nilsson, Sara; Sjöberg, Johanna; Amundin, Mats; Hartmann, Constanze; Buettner, Andrea; Laska, Matthias

    2014-01-01

    Only little is known about whether single volatile compounds are as efficient in eliciting behavioral responses in animals as the whole complex mixture of a behaviorally relevant odor. Recent studies analysing the composition of volatiles in mammalian blood, an important prey-associated odor stimulus for predators, found the odorant trans-4,5-epoxy-(E)-2-decenal to evoke a typical "metallic, blood-like" odor quality in humans. We therefore assessed the behavior of captive Asian wild dogs (Cuon alpinus), African wild dogs (Lycaon pictus), South American bush dogs (Speothos venaticus), and Siberian tigers (Panthera tigris altaica) when presented with wooden logs that were impregnated either with mammalian blood or with the blood odor component trans-4,5-epoxy-(E)-2-decenal, and compared it to their behavior towards a fruity odor (iso-pentyl acetate) and a near-odorless solvent (diethyl phthalate) as control. We found that all four species displayed significantly more interactions with the odorized wooden logs such as sniffing, licking, biting, pawing, and toying, when they were impregnated with the two prey-associated odors compared to the two non-prey-associated odors. Most importantly, no significant differences were found in the number of interactions with the wooden logs impregnated with mammalian blood and the blood odor component in any of the four species. Only one of the four species, the South American bush dogs, displayed a significant decrease in the number of interactions with the odorized logs across the five sessions performed per odor stimulus. Taken together, the results demonstrate that a single blood odor component can be as efficient in eliciting behavioral responses in large carnivores as the odor of real blood, suggesting that trans-4,5-epoxy-(E)-2-decenal may be perceived by predators as a "character impact compound" of mammalian blood odor. Further, the results suggest that odorized wooden logs are a suitable manner of environmental enrichment

  6. Investigation of molecular metabolites in expired air of healthy man in condition of long-term isolation in hermetical confined environment

    NASA Astrophysics Data System (ADS)

    Tsarkov, Dmitriy; Mardanov, Robert; Markin, Andrey; Moukhamedieva, Lana

    Investigation of intermediary metabolites, produced in cells, in expired air of healthy man is directed on determination of molecular markers which are reflecting normal physiological pro-cesses in an organism, as well as on determination and validation of biomarkers for objective screening and non-invasive prenosological diagnostics of disorders in metabolic processes caused by negative effect of live environment. Investigation of influence of long-term isolation in her-metical confined environment on composition of healthy human expired air was made during experiment with 105 days isolation in condition of controlled environment and standard food ra-tion. Expired air samples were analyzed on gas chromatograph associated with the quadrupole mass spectrometer. The investigation results show that at rest hydroxy ketones, mostly 1-hydroxy-prorapanone-2 (acetol), aldehydes (decenal, benzaldehyde), acetophenone, phenol and fatty acids were determined. After physical performance (oxidative stress) the content of ke-tones (heptanone-2, heptanone-3), phenol, determined aldehydes (decenal, octadecenal) and acetol in expired air of volunteers decreased. It can be concerned with prevailing of alternative -methylglyoxalic metabolic pathway and caused by oxidative stress. Analysis of expired air samples taken on 30, 60 and 90 day of isolation showed that in conditions of long-term iso-lation concentration of heptanone-2, heptanone-3, 2,3-butadione, acetol, furanones, aldehydes (decenal, benzaldehyde) and acetophenone is increasing while concentration of phenol and fatty acids is decreasing as compared to samples taken before isolation. It was shown that dynamics of concentration of saturated hydrocarbons in expired air can be informative marker for estima-tion of organism response to oxidative stress, while the level of acetol can be used as indicator of man's training status, validity of exercise load and as a marker of hypoxic state.

  7. Pharmacological activities of cilantro's aliphatic aldehydes against Leishmania donovani.

    PubMed

    Donega, Mateus A; Mello, Simone C; Moraes, Rita M; Jain, Surendra K; Tekwani, Babu L; Cantrell, Charles L

    2014-12-01

    Leishmaniasis is a chronic infectious disease caused by different Leishmania species. Global occurrences of this disease are primarily limited to tropical and subtropical regions. Treatments are available; however, patients complain of side effects. Different species of plants have been screened as a potential source of new drugs against leishmaniasis. In this study, we investigated the antileishmanial activity of cilantro (Coriandrum sativum) essential oil and its main components: (E)-2-undecenal, (E)-2-decenal, (E)-2-dodecenal, decanal, dodecanal, and tetradecanal. The essential oil of C. sativum leaves inhibits growth of Leishmani donovani promastigotes in culture with an IC50 of 26.58 ± 6.11 µg/mL. The aliphatic aldehydes (E)-2-decenal (7.85 ± 0.28 µg/mL), (E)-2-undecenal (2.81 ± 0.21 µg/mL), and (E)-2-dodecenal (4.35 ± 0.15 µg/mL), all isolated from C. sativum essential oil, are effective inhibitors of in vitro cultures of L. donovani promastigotes. Aldehydes (E)-2-decenal, (E)-2-undecenal, and (E)-2-dodecenal were also evaluated against axenic amastigotes and IC50 values were determined to be 2.47 ± 0.25 µg/mL, 1.25 ± 0.11 µg/mL, and 4.78 ± 1.12 µg/mL, respectively. (E)-2-Undecenal and (E)-2-dodecenal demonstrated IC50 values of 5.65 ± 0.19 µg/mL and 9.60 ± 0.89 µg/mL, respectively, against macrophage amastigotes. These cilantro compounds showed no cytotoxicity against THP-1 macrophages. PMID:25340465

  8. Behavioral Responses to Mammalian Blood Odor and a Blood Odor Component in Four Species of Large Carnivores

    PubMed Central

    Nilsson, Sara; Sjöberg, Johanna; Amundin, Mats; Hartmann, Constanze; Buettner, Andrea; Laska, Matthias

    2014-01-01

    Only little is known about whether single volatile compounds are as efficient in eliciting behavioral responses in animals as the whole complex mixture of a behaviorally relevant odor. Recent studies analysing the composition of volatiles in mammalian blood, an important prey-associated odor stimulus for predators, found the odorant trans-4,5-epoxy-(E)-2-decenal to evoke a typical “metallic, blood-like” odor quality in humans. We therefore assessed the behavior of captive Asian wild dogs (Cuon alpinus), African wild dogs (Lycaon pictus), South American bush dogs (Speothos venaticus), and Siberian tigers (Panthera tigris altaica) when presented with wooden logs that were impregnated either with mammalian blood or with the blood odor component trans-4,5-epoxy-(E)-2-decenal, and compared it to their behavior towards a fruity odor (iso-pentyl acetate) and a near-odorless solvent (diethyl phthalate) as control. We found that all four species displayed significantly more interactions with the odorized wooden logs such as sniffing, licking, biting, pawing, and toying, when they were impregnated with the two prey-associated odors compared to the two non-prey-associated odors. Most importantly, no significant differences were found in the number of interactions with the wooden logs impregnated with mammalian blood and the blood odor component in any of the four species. Only one of the four species, the South American bush dogs, displayed a significant decrease in the number of interactions with the odorized logs across the five sessions performed per odor stimulus. Taken together, the results demonstrate that a single blood odor component can be as efficient in eliciting behavioral responses in large carnivores as the odor of real blood, suggesting that trans-4,5-epoxy-(E)-2-decenal may be perceived by predators as a “character impact compound” of mammalian blood odor. Further, the results suggest that odorized wooden logs are a suitable manner of environmental

  9. A property-matched water-soluble analogue of the benchmark ligand PPh3.

    PubMed

    Ferreira, Michel; Bricout, Hervé; Hapiot, Frédéric; Sayede, Adlane; Tilloy, Sébastien; Monflier, Eric

    2008-01-01

    A series of sulfonated biphenylphosphanes were readily prepared from commercially available, inexpensive, and air-stable organic compounds. Of these, the trisulfonated trisbiphenylphosphane can be considered as a true water-soluble analogue of PPh(3) as the cone angle and basicity of both phosphanes are very close and result in a similar coordination mode on palladium and rhodium complexes. The catalytic performance of the trisulfonated trisbiphenylphosphane was evaluated in the aqueous hydroformylation of 1-decene and the Tsuji-Trost reaction. PMID:18702165

  10. Optofluidic laser array based on stable high-Q Fabry-Pérot microcavities.

    PubMed

    Wang, Wenjie; Zhou, Chunhua; Zhang, Tingting; Chen, Jingdong; Liu, Shaoding; Fan, Xudong

    2015-10-01

    We report the development of an optofluidic laser array fabricated on a chip using stable plano-concave Fabry-Pérot (FP) microcavities, which are far less susceptible to optical misalignment during device assembly than the commonly used plano-plano FP microcavities. The concave mirrors in our FP microcavities were created by first generating an array of microwells of a few micrometers in depth and a few tens of micrometers in diameter on a fused silica chip using a CO2 laser, followed by coating of distributed Bragg reflection (DBR) layers. The plano-concave FP microcavity had a Q-factor of 5.6 × 10(5) and finesse of 4 × 10(3), over 100 times higher than those for the FP microcavities in existing optofluidic lasers. 1 mM R6G dye in ethanol was used to test the plano-concave FP microcavities, showing an ultralow lasing threshold of only 90 nJ mm(-2), over 10 times lower than that in the corresponding unstable plano-plano FP microcavities formed by the same DBR coatings on the same chip. Simultaneous laser emission from the optofluidic laser array on the chip and single-mode lasing operation were also demonstrated. Our work will lead to the development of optofluidic laser-based biochemical sensors and novel on-chip photonic devices with extremely low lasing thresholds (nJ mm(-2)) and mode volumes (fL). PMID:26304622

  11. Characterization of epoxydecenal isomers as potent odorants in black tea (Dimbula) infusion.

    PubMed

    Kumazawa, Kenji; Wada, Yoshiyuki; Masuda, Hideki

    2006-06-28

    In a black tea (Dimbula) infusion, the potent "sweet and/or juicy" odorants were identified as the cis- and trans-4,5-epoxy-(E)-2-decenals by comparison of their gas chromatography retention indices, mass spectra, and odor quality to those of the actual synthetic compounds. Of the two odorants, cis-4,5-epoxy-(E)-2-decenal has been identified for the first time in the black tea. On the basis of the aroma extract dilution analysis on the flavor distillate obtained using the solvent-assisted flavor evaporation technique from the black tea infusion, these isomers showed higher flavor dilution (FD) factors. The FD factors and concentrations of these odorants in the black tea infusion were observed to be much higher than those from Japanese green tea. In addition, the model studies showed that these odorants were generated from linoleic acid and its hydroperoxides by heating, but the generated amounts of these odorants from linoleic acid were much less than those of its hydroperoxides. It can be assumed from these results that the withering and fermentation, which are characteristic processes during the manufacturing of the black tea, which includes the enzymatic reaction such as lipoxygenase, is one of the most important factors for the formation of the epoxydecenal isomers. PMID:16787030

  12. Identification of the sex pheromone secreted by a nettle moth, Monema flavescens, using gas chromatography/fourier transform infrared spectroscopy.

    PubMed

    Shibasaki, Hiroshi; Yamamoto, Masanobu; Yan, Qi; Naka, Hideshi; Suzuki, Toshiro; Ando, Tetsu

    2013-03-01

    The nettle moth Monema flavescens (Limacodidae) is a defoliator of fruit trees, such as Chinese plum and persimmon. The larvae of this species have spines containing a poison that causes serious irritation and inflammation in humans. Coupled gas chromatography-electroantennogram detection and gas chromatography/mass spectrometry analyses of a crude pheromone extract, combined with derivatization, indicated that female moths produced 8-decen-1-ol and 7,9-decadien-1-ol at a ratio of approximately 9:1. The E configuration of the double bonds was assigned for both components from infrared spectra, recorded on a gas chromatograph/Fourier transform-infrared spectrophotometer equipped with a zinc selenide disk cooled to -30 °C. The monoenyl and dienyl alcohols had absorptions characteristic of E geometry at 966 and 951 cm(-1), respectively. A band chromatogram at 951 cm(-1) was useful for distinguishing geometric isomers, because terminal conjugated diene are difficult to resolve, even on high polarity columns. Furthermore, we identified the Z configuration of the same 7,9-dienyl alcohol secreted by another nettle moth, Parasa lepida lepida, through the absence of this absorption. In field trials, lures baited with a 9:1 mixture of (E)-8-decen-1-ol and (E)-7,9-decadien-1-ol attracted M. flavescens males. Furthermore, the field trials indicated that contamination with the (Z)-diene reduced catches to the pheromone mixture more than did contamination with the (Z)-monoene. PMID:23400496

  13. Aroma-active components of nonfat dry milk.

    PubMed

    Karagül-Yüceer, Y; Drake, M A; Cadwallader, K R

    2001-06-01

    Application of aroma extract dilution analysis (AEDA) on the volatile components of low-, medium-, and high-heat-treated nonfat dry milks (NDM) revealed aroma-active compounds in the log(3) flavor dilution (log(3) FD) factor range of 1 to 6. The following compounds contributed the highest log(3) FD factors to overall NDM flavor: 2,5-dimethyl-4-hydroxy-3(2H)-furanone [(Furaneol), burnt sugar-like]; butanoic acid (rancid); 3-(methylthio)propanal [(methional), boiled potato-like]; o-aminoacetophenone (grape-like); delta-decalactone (sweet); (E)-4,5-epoxy-(E)-2-decenal (metallic); pentanoic acid (sweaty); 4,5-dimethyl-3-hydroxy-2(5H)-furanone [(sotolon), curry]; 3-methoxy-4-hydroxybenzaldehyde [(vanillin), vanilla]; 2-acetyl-1-pyrroline and 2-acetyl-2-thiazoline (popcorn-like); hexanoic acid (vinegar-like); phenylacetic acid (rose-like); octanoic acid (waxy); nonanal (fatty); and 1-octen-3-one (mushroom-like). The odor intensities of Furaneol, butanoic acid, methional, o-aminoacetophenone, sotolon, vanillin, (E)-4,5-epoxy-(E)-2-decenal, and phenylacetic acid were higher in high-heat-treated samples than others. However, the odor intensities of lactones, 2-acetyl-1-pyrroline, and 2-acetyl-2-thiazoline were not affected by heat treatment. Sensory evaluation results also revealed that heat-generated flavors have a major impact on the flavor profile of NDM. PMID:11409991

  14. Metathesis process for preparing an alpha, omega-functionalized olefin

    DOEpatents

    Burdett, Kenneth A.; Mokhtarzadeh, Morteza; Timmers, Francis J.

    2010-10-12

    A cross-metathesis process for preparing an .alpha.,.omega.-functionalized olefin, such as methyl 9-decenoate, and an .alpha.-olefin having three or more carbon atoms, such as 1-decene. The process involves contacting in a first reaction zone an .alpha.-functionalized internal olefin, such as methyl oleate, and an .alpha.-olefinic monomer having three or more carbon atoms, such as 1-decene, with a first metathesis catalyst to prepare an effluent stream containing the .alpha.,.omega.-functionalized olefin, such as methyl 9-decenoate, an unfunctionalized internal olefin, such as 9-octadecene, unconverted reactant olefins, and optionally, an .alpha.,.omega.-difunctionalized internal olefinic dimer, such as dimethyl 9-octadecen-1,18-dioate; separating said effluent streams; then contacting in a second reaction zone the unfunctionalized internal olefin with ethylene in the presence of a second metathesis catalyst to obtain a second product effluent containing the .alpha.-olefinic monomer having three or more carbon atoms; and cycling a portion of the .alpha.-olefinic monomer stream(s) to the first zone.

  15. Hydroconversion of liquid hydrocarbons in a staged autothermal reactor

    SciTech Connect

    Blass, SD; Bhan, A; Schmidt, LD

    2013-01-31

    An autothermal staged reactor was assembled containing a top stage of Rh-Ce/alpha-Al2O3 which generated heat and H-2 by reacting CH4 and air that passed through a downstream stage containing 0.5 wt% Pt/gamma-Al2O3 mixed with either HBEA, HZSM-5, or USY in a heat-integrated non-isothermal reactor. The H-2 produced subsequently reacts in a 20:1 ratio with a co-feed of hexane or decane or 2-decanone fed to the reactor between the stages. The large-sized pores of HBEA and USY allowed deoxygenation of 2-decanone to form decene isomers which can crack or cyclize to form up to a 36% yield of methylated and ethylated monoaromatics. The medium-sized pores of HZSM-5 restricted decene formation from 2-decanone by catalyzing cracking reactions to C2-6 compounds which can cyclize to form aromatics. By contrast, the reactor effluent from non-oxygenated reactants decane and hexane contained less than 5% aromatics. Thus, we extend the scope of staged autothermal reactor functionality to hydrocracking and hydroisomerization of higher saturated and oxygenated hydrocarbons. (C) 2012 Elsevier B.V. All rights reserved.

  16. Characterisation of aroma-active and off-odour compounds in German rainbow trout (Oncorhynchus mykiss). Part I: Case of aquaculture water from earthen-ponds farming.

    PubMed

    Mahmoud, Mohamed Ahmed Abbas; Buettner, Andrea

    2016-11-01

    Comprehensive analyses were accomplished to explore the odorous molecules responsible for off-odour development in earthen-ponds rainbow trout (Oncorhynchus mykiss) aquaculture farming in Germany. In this part of the study, water odorants were extracted using solvent-assisted flavour evaporation (SAFE); then, extracts were analysed by one- and two- dimensional high resolution gas chromatography coupled with olfactometry and mass spectrometry using two columns with different polarity (DB-FFAP and DB-5). Aroma extract dilution analysis (AEDA) of the solvent extract samples revealed 54 odorants, and 47 of them were identified. In this study, a series of compounds is described for the first time in German earthen-ponds rainbow trout aquaculture water including, amongst others, 4-hydroxy-2,5-dimethyl-3(2H)-furanone (furaneol), vanillin, (E)-4,5-epoxy-(E)-2-decenal, 4-ethyloctanoic acid, 3-methylindole (skatole), 5α-androst-16-en-3-one (androstenone), and 2-(2-butoxyethoxy) ethanol. Moreover, the sensory experiment indicated that (E)-4,5-epoxy-(E)-2-decenal, (E,E)-2,4-octadienal, and 1-octen-3-one are the main contributors to the metallic, cucumber, and mushroom notes of the samples. PMID:27211690

  17. Types of Contact Lenses

    MedlinePlus

    ... Consumer Devices Consumer Products Contact Lenses Types of Contact Lenses Share Tweet Linkedin Pin it More sharing ... Orthokeratology (Ortho-K) Decorative (Plano) Contact Lenses Soft Contact Lenses Soft contact lenses are made of soft, ...

  18. 13. Historic American Buildings Survey Photocopy, Plan of 1784 From ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Historic American Buildings Survey Photocopy, Plan of 1784 From Mapas y Planos-Luisiana y Archivo General de Indias, Seville Florida 99 - Bateria de San Antonio, San Carlos & Hovey Roads, Pensacola, Escambia County, FL

  19. Academic Village.

    ERIC Educational Resources Information Center

    Boles, Rebecca

    2001-01-01

    Presents design features of the Renner Middle School (Plano, Texas) where the sprawling suburbs have been kept at bay while creating the atmosphere of an academic village. Photos and a floor plan are provided. (GR)

  20. Refraction test

    MedlinePlus

    ... purpose is to determine whether you have a refractive error (a need for glasses or contact lenses). ... glasses or contact lenses) is normal, then the refractive error is zero (plano) and your vision should ...

  1. Wavefront-guided versus standard laser in situ keratomileusis to correct low to moderate myopia.

    PubMed

    Nuijts, Rudy M M A; Nabar, Vaishaly A; Hament, Willem J; Eggink, Fred A G J

    2002-11-01

    To evaluate the 6-month refractive outcomes of wavefront-guided laser in situ keratomileusis (LASIK) (Zyoptix, Bausch & Lomb) versus standard LASIK (PlanoScan, Bausch & Lomb). Department of Ophthalmology, University Hospital Maastricht, Maastricht, The Netherlands. In a prospective randomized study, 12 patients with myopia had Zyoptix wavefront-guided LASIK in 1 eye and PlanoScan LASIK in the contralateral eye. The safety, efficacy, predictability, stability, optical zone size, and ablation depth were evaluated. The mean preoperative spherical equivalent (SE) of the subjective manifest refraction was -3.88 diopters (D) +/- 1.92 (SD) (Zyoptix) and -4.35 +/- 2.11 D (PlanoScan). Six months postoperatively, 8% of PlanoScan patients and 16% of Zyoptix patients gained at least 2 lines of best corrected visual acuity; the safety index was 1.12 in the Zyoptix group and 1.08 in the PlanoScan group. An SE of +/-1.00 D and +/-0.50 D was achieved by 100% and 92%, respectively, in both groups. There were 2 undercorrections in the Zyoptix group and 1 undercorrection in the PlanoScan group. In the Zyoptix group, 100% had a UCVA of 20/40 and 67% of 20/20 and in the PlanoScan group, 100% and 83%, respectively. The efficacy index was 0.87 and 0.93 in the Zyoptix group and PlanoScan group, respectively. The mean optical zone 6 months postoperatively was 6.16 +/- 0.34 mm in the PlanoScan group and 6.23 +/- 0.41 mm in the Zyoptix group (P =.67). The ablation depth per diopter of defocus equivalent was 13.5 +/- 4.6 microm/D and 8.6 +/- 4.4 microm/D, respectively (P =.01).An excellent safety index was achieved with the Zyoptix and PlanoScan treatments. The efficacy index was marginally lower for Zyoptix treatments as a result of 2 undercorrections. The ablation depth in the Zyoptix group per diopter of defocus equivalent was significantly lower than in the PlanoScan group. Further refinements in defining the ablation algorithms may increase the efficacy index. PMID:12457662

  2. Q-switched Ho:Lu2O3 laser at 2.12 μm.

    PubMed

    Lamrini, Samir; Koopmann, Philipp; Scholle, Karsten; Fuhrberg, Peter

    2013-06-01

    We report on a Q-switched Ho:Lu2O3 laser resonantly pumped by a GaSb-based laser diode stack at 1.9 μm. The maximum output energy extracted from the compact plano-plano acousto-optically Q-switched resonator was 8 mJ at a 100 Hz pulse repetition rate, while the peak power was 40 kW. The laser wavelength was 2.124 μm. PMID:23722799

  3. An intuitive concept for manufacturing and inspecting of aspherical components

    NASA Astrophysics Data System (ADS)

    Chou, Hsiao-Yu; Chang, Keng-Shou

    2011-09-01

    In this paper we propose an intuitive concept for manufacturing and inspecting of aspherical components. Two types, parabolic and cylinder, of plano-convex and plano-concave aspherical lenses were made by LOH 120S form generation machine. Three form error measurement methods were used known as coordinate measuring machine (CMM), interferometer with CGH null lens and inspection with combined pair lenses. Ultra high accuracy CMM from Panasonic Co., CGH cylinder null and CGH aspheric null from Diffraction International and OWI 150 ASPH CGH interferometer from OptoTech GmbH play the roll for measurement. CMM was used as a surface profiler to inspect the surface shape, and the software GRAPHER was also used as analysis tool to exam asphere numerical datum. The difference between theoretical and practical is as a surface polishing revised reference. The finished plano-convex and plano-concave aspherical lenses can be combined to be a plane lens. The individual and combined lenses were inspected on OPTOTECH OWI 150 ASPH CGH interferometer. The compared interference patterns have shown with the Diffration International CGH Aspheric Null "ASPHERIC 1" and CGH Cylinder Null "H80F2C". Through the procedure, the combined plano-convex and plano-concave aspherical lenses should be a perfect match plane lens and the individual lens might be an aspherical test standard element for quick inspection.

  4. Non-Biological Barriers to Referral and the Pre-Kidney Transplant Evaluation Among African Americans in the United States: A Systematic Review.

    PubMed

    Lockwood, Mark B; Bidwell, Julie T; Werner, Debra A; Lee, Christopher S

    2016-01-01

    African Americans face a disproportionate burden related to the incidence of end stage renal disease. A literature search was conducted for research articles published between 2006-2015 to synthesize current literature related to non-biological barriers to early stages of the pre-kidney transplant continuum for African Americans in the United States. Twenty-four articles were included in the final sample. Eleven barriers were identified. Barriers were categorized as socioeconomic-based barriers, culture-based barriers, and knowledge-based barriers. Resources to develop educational interventions for both patients and providers may help reduce existing barriers. PMID:27501630

  5. Critical evaluation of the Global DOTS Expansion Plan.

    PubMed

    Enarson, Donald A; Billo, Nils E

    2007-05-01

    The development of the DOTS Expansion Plan has been a milestone in tuberculosis (TB) control at the global and national levels. Key challenges that remain are overcoming the weakness of a strategy built on case management, sustaining commitment, competing priorities, the threat of HIV, maintaining high quality of care and preventing drug resistance, building human resource capacity, improving diagnosis and fostering operations research. The ability to address these challenges will determine the success or failure of the Global Plan to Stop TB, 2006-2015. PMID:17639227

  6. [PROGNOSTICATION OF "HARD" TRACHEAL INTUBATION IN PATIENTS, SUFFERING PURULENT-INFLAMMATORY DISEASES OF THE JAW-FACIAL REGION].

    PubMed

    Artemenko, V Yu; Budnyuk, O O

    2015-11-01

    Clinical follow-up was conducted in 75 patients, to whom the operation and intensive therapy were performed in 2006-2015 yrs for phlegmon of the neck. Difficulties while providing passability of respiratory ways have occurred in 73.3% patients. It was established, that the predictors of "hard" tracheal intubation in patients, operated on for cervical phlegmon, are follows: the cervical tissues oedema, restriction of the mouth opening lesser than 3 cm, odontogenous phlegmon of oral cavity and the neck, rigid epiglottis, the larynx oedema. Presence of these factors demands application of endoscopic methods for tracheal intubation in such patients. PMID:26939430

  7. Enhanced photolysis in aerosols: evidence for important surface effects.

    PubMed

    Nissenson, Paul; Knox, Christopher J H; Finlayson-Pitts, Barbara J; Phillips, Leon F; Dabdub, Donald

    2006-10-28

    While there is increasing evidence for unique chemical reactions at interfaces, there are fewer data on photochemistry at liquid-vapor junctions. This paper reports a comparison of the photolysis of molybdenum hexacarbonyl, Mo(CO)(6), in 1-decene either as liquid droplets or in bulk-liquid solutions. Mo(CO)(6) photolysis is faster by at least three orders of magnitude in the aerosols than in bulk-liquids. Two possible sources of this enhancement are considered: (1) increased light intensity due to either Morphology-Dependent Resonances (MDRs) in the spherical aerosol particles and/or to increased pathlengths for light inside the droplet due to refraction, which are termed physical effects in this paper; and (2) interface effects such as an incomplete solvent-cage at the gas-liquid boundary and/or enhanced interfacial concentrations of Mo(CO)(6), which are termed chemical effects. Quantitative calculations of the first possibility were carried out in which the light intensity distribution in the droplets averaged over 215-360 nm was obtained for 1-decene droplets. Calculations show that the average increase in light intensity over the entire droplet is 106%, with an average increase of 51% at the interface. These increases are much smaller than the observed increase in the apparent photolysis rate of droplets compared to the bulk. Thus, chemical effects, i.e., a decreased solvent-cage effect at the interface and/or enhancement in the surface concentration of Mo(CO)(6), are most likely responsible for the dramatic increase in the photolysis rate. Similar calculations were also carried out for broadband (290-600 nm) solar irradiation of water droplets, relevant to atmospheric conditions. These calculations show that, in agreement with previous calculations by Mayer and Madronich [B. Mayer and S. Madronich, Atmos. Chem. Phys., 2004, 4, 2241] MDRs produce only a moderate average intensity enhancement relative to the corresponding bulk-liquid slabs when averaged over a

  8. Pharmacologic Plus Optical Penalization Treatment for Amblyopia: Results of a Randomized Trial

    PubMed Central

    2008-01-01

    Objective To compare weekend atropine augmented by a plano lens for the sound eye with weekend atropine alone for moderate amblyopia in children 3 to <7 years old. Methods In a multi-center clinical trial, 180 children with moderate amblyopia (20/40 to 20/100) were randomized to weekend atropine augmented by a plano lens or weekend atropine alone. Main Outcome Measure Masked assessment of amblyopic eye visual acuity using the Amblyopia Treatment Study HOTV testing protocol at 18 weeks. Results At 18 weeks, amblyopic eye improvement averaged 2.8 lines in the atropine plus plano lens group and 2.4 lines in the atropine alone group (mean difference between groups adjusted for baseline acuity 0.3 lines; 95% confidence interval, −0.2 to 0.8). Amblyopic eye acuity was 20/25 or better in 24 (29%) patients in the atropine-only group and 35 (40%) patients in the atropine plus plano lens group (P=0.03). More patients in the atropine plus plano lens group had reduced sound eye acuity at 18 weeks; however, there were no cases of persistent reverse amblyopia. Conclusions As an initial treatment for moderate amblyopia, the augmentation of weekend atropine with a plano lens does not substantially improve amblyopic eye acuity when compared with atropine alone. Application to Clinical Practice Treatment of children with unilateral amblyopia Trial Registry Name Trial Comparing Atropine to Atropine Plus a Plano Lens for the Sound Eye for Amblyopia in Children 3 to <7 Years Old PMID:19139333

  9. Evolved gas analysis of secondary organic aerosols

    SciTech Connect

    Grosjean, D.; Williams, E.L. II; Grosjean, E. ); Novakov, T. )

    1994-11-01

    Secondary organic aerosols have been characterized by evolved gas analysis (EGA). Hydrocarbons selected as aerosol precursors were representative of anthropogenic emissions (cyclohexene, cyclopentene, 1-decene and 1-dodecene, n-dodecane, o-xylene, and 1,3,5-trimethylbenzene) and of biogenic emissions (the terpenes [alpha]-pinene, [beta]-pinene and d-limonene and the sesquiterpene trans-caryophyllene). Also analyzed by EGA were samples of secondary, primary (highway tunnel), and ambient (urban) aerosols before and after exposure to ozone and other photochemical oxidants. The major features of the EGA thermograms (amount of CO[sub 2] evolved as a function of temperature) are described. The usefulness and limitations of EGA data for source apportionment of atmospheric particulate carbon are briefly discussed. 28 refs., 7 figs., 4 tabs.

  10. Process for the synthesis of unsaturated alcohols

    DOEpatents

    Maughon, Bob R.; Burdett, Kenneth A.; Lysenko, Zenon

    2007-02-13

    A process of preparing an unsaturated alcohol (olefin alcohol), such as, a homo-allylic mono-alcohol or homo-allylic polyol, involving protecting a hydroxy-substituted unsaturated fatty acid or fatty acid ester, such as methyl ricinoleate, derived from a seed oil, to form a hydroxy-protected unsaturated fatty acid or fatty acid ester; homo-metathesizing or cross-metathesizing the hydroxy-protected unsaturated fatty acid or fatty acid ester to produce a product mixture containing a hydroxy-protected unsaturated metathesis product; and deprotecting the hydroxy-protected unsaturated metathesis product under conditions sufficient to prepare the unsaturated alcohol. Preferably, methyl ricinoleate is converted by cross-metathesis or homo-metathesis into the homo-allylic mono-alcohol 1-decene-4-ol or the homo-allylic polyol 9-octadecene-7,12-diol, respectively.

  11. Heteropteran chemical repellents identified in the citrus odor of a seabird (crested auklet: Aethia cristatella): evolutionary convergence in chemical ecology

    NASA Astrophysics Data System (ADS)

    Douglas, H. D.; Co, J. E.; Jones, T. H.; Conner, W. E.

    2001-08-01

    The exogenous application of chemical repellents is widespread in birds, but endogenous production is exceedingly rare. We herein report a new class of avian defensive compounds isolated from the feathers and volatile odor of the crested auklet ( Aethia cristatella). Mass spectra indicate that n-hexanal, n-octanal, n-decanal, Z-4-decenal and a 12-carbon unsaturated aldehyde comprise the auklet odorant. Octanal and hexanal are also secreted in the repugnant metasternal gland emissions of heteropteran insects and are known to be potent invertebrate repellents. We suggest that the auklet odorant functions as an ectoparasite repellent and a signal of mate quality. This would represent a rare and direct link between vigor, quality and parasite resistance, one of several putative bases for mate selection. This is the first report of defensive compounds produced by a seabird or colonial bird and one of the few examples of chemical defense in a polar or subpolar marine vertebrate.

  12. Titanium compounds as catalysts of higher alpha-olefin-based super-high-molecular polymers synthesis

    NASA Astrophysics Data System (ADS)

    Konovalov, K. B.; Kazaryan, M. A.; Manzhay, V. N.; Vetrova, O. V.

    2016-01-01

    The synthesis of polymers of 10 million or more molecular weight is a difficult task even in a chemical lab. Higher α-olefin-based polymer agents of such kind have found a narrow but quite important niche, the reduction of drag in the turbulent flow of hydrocarbon fluids such as oil and oil-products. In its turn, searching for a catalytic system capable to produce molecules of such a high length and to synthesize polymers of a low molecular-mass distribution is part of a global task of obtaining a high-quality product. In this paper we had observed a number of industrial catalysts with respect to their suitability for higher poly-α- olefins synthesis. A number samples representing copolymers of 1-hexene with 1-decene obtained on a previous generation catalyst, a microsphere titanium chloride catalytic agent had been compared to samples synthesized using a titanium-magnesium catalyst both in solution and in a polymer medium.

  13. Continuous Flow Metathesis for Direct Valorization of Food Waste: An Example of Cocoa Butter Triglyceride

    PubMed Central

    2015-01-01

    The direct chemical conversion of cocoa butter triglycerides, a material available as a postmanufacture waste stream from the food industry, to 1-decene by way of ethenolysis is reported. The conversion of the raw waste material was made possible by use of 1 mol % of the [RuCl2(iBu-phoban)2(3-phenylindenyl)] catalyst. The process has been investigated in both batch and flow conditions, where the latter approach employs a Teflon AF-2400 tube-in-tube gas–liquid membrane contactor to deliver ethylene to the reaction system. These preliminary studies culminate in a continuous processing system, which maintained a constant output over a 150 min period tested. PMID:26322250

  14. Simultaneous determination of ten taste and odor compounds in drinking water by solid-phase microextraction combined with gas chromatography-mass spectrometry.

    PubMed

    Chen, Xichao; Luo, Qian; Yuan, Shengguang; Wei, Zi; Song, Hanwen; Wang, Donghong; Wang, Zijian

    2013-11-01

    Taste and odor (T&O) problems in drinking water frequently occur because of many compounds present in the water, of which trans-1,10-dimethyl-trans-9-decalol (geosmin) and 2-methylisoborneol (MIB) are well-known. In this study, a fast and effective method was established for simultaneous determination of 10 T&O compounds, including geosmin, MIB, 2,4,6-trichloroanisole (TCA), 2-methylbenzofuran, 2-isopropyl-3-methoxypyrazine (IPMP), 2-isobutyl-3-methoxypyrazine (IBMP), cis-3-hexenyl acetate, trans,trans-2,4-heptadienal, trans, cis-2,6-nonadienal, and trans-2-decenal in water samples by headspace solid-phase microextraction (SPME) coupled with gas chromatography-mass spectrometry. An orthogonal array experimental design was used to optimize the effects of SPME fiber, extraction temperature, stirring rate, NaCI content, extraction time, and desorption time. The limits of detection ranged from 0.1 to 73 ng/L were lower than or close to the odor threshold concentrations (OTCs). All the 10 T&O compounds were detected in the 14 water samples including surface water, treatment process water and tap water, taken from a waterworks in Lianyungang City, China. MB and geosmin were detected in most samples at low concentration. Six T&O compounds (IPMP, IBMP, trans,cis-2,6-nonadienal, 2-methylbenzofuran, trans-2-decenal, and TCA) were effectively decreased in water treatment process (sedimentation and filtration) that is different from cis-3-hexenyl acetate, MIB and geosmin. It is noted that the TCA concentrations at 15.9-122.3 ng/L and the trans,cis-2,6-nonadienal concentrations at 79.9-190.1 ng/L were over 10 times higher than their OTCs in tap water. The variation of the analytes in the all water samples, especially distribution system indicated that distribution system cannot be ignored as a T&O compounds source. PMID:24552061

  15. Estudio de los Efectos Gravitomagnéticos en Cuerpos Masivos Rotantes

    NASA Astrophysics Data System (ADS)

    Velandia Heredia, N.; Tejeiro, J. M.

    2008-03-01

    A partir del estudio de los Efectos Gravitomagnéticos en cuerpos masivos rotantes, planteamos la expresión para medir el desfase en el tiempo, para diferentes observadores, que se dan cuando viajan dos rayos de luz por una guía de onda o de manera libre (geodésicas), en el plano azimutal y en el plano polar. Con lo anterior queremos abordar el experimento tipo Michelson y Morley, de forma que podamos involucrar el valor de la densidad del momento angular (a) en el retraso temporal para los dos haces de luz que viajan por los brazos del interferómetro, cuando este último es ubicado en el plano ecuatorial.

  16. Ca3La2(BO3)4 crystal: a new candidate host material for the ytterbium ion

    NASA Astrophysics Data System (ADS)

    Wang, Yeqing; You, Zhenyu; Zhu, Zhaojie; Xu, Jinlong; Li, Jianfu; Wang, Yan; Wang, Hongyan; Tu, Chaoyang

    2013-10-01

    A disordered laser crystal Yb3+-doped Ca3La2(BO3)4 crystal was grown by the Czochralski technique. The characterized room temperature polarized spectra, re-absorption possibility and laser performance showed that this crystal should be a promising gain material, not only suitable for diode pumping, but also a good candidate for the generation of tunable and short pulse lasers. End pumped by a diode laser at 976 nm in plano-concave and plano-plano cavity, a 3.65 W output power with a slope efficiency of 65% was achieved by using a c-cut Yb3+:Ca3La2(BO3)4 crystal. The output laser wavelength shifted from 1042 to 1062 nm.

  17. Optomechanical characterization of acoustic modes in a mirror

    SciTech Connect

    Briant, T.; Cohadon, P.-F.; Heidmann, A.; Pinard, M.

    2003-09-01

    We present an experimental study of the internal mechanical vibration modes of a mirror. We determine the frequency repartition of acoustic resonances via a spectral analysis of the Brownian motion of the mirror, and the spatial profile of the acoustic modes by monitoring their mechanical response to a resonant radiation pressure force swept across the mirror surface. We have applied this technique to mirrors with cylindrical and plano-convex geometries, and compared the experimental results to theoretical predictions. We have in particular observed the Gaussian modes predicted for plano-convex mirrors.

  18. 219.3 W CW diode-side-pumped 1123 nm Nd:YAG laser

    NASA Astrophysics Data System (ADS)

    Li, C. Y.; Bo, Y.; Xu, Y. T.; Yang, F.; Wang, Z. C.; Wang, B. S.; Xu, J. L.; Gao, H. W.; Peng, Q. J.; Cui, D. F.; Xu, Z. Y.

    2010-07-01

    We demonstrate a high power continuous wave (CW) diode-side-pumped Nd:YAG laser operating at 1123 nm with a plano-plano configuration. By means of precise coating, a single 1123 nm wavelength is achieved. Under the pump power of 1080 W, an output power of 219.3 W is obtained, which corresponds to an optical-optical conversion efficiency of 20.3%. To the best of our knowledge, this is the highest output power for CW 1123 nm laser based on Nd:YAG crystal.

  19. 93.7 W 1112 nm diode-side-pumped CW Nd:YAG laser

    NASA Astrophysics Data System (ADS)

    Li, C. Y.; Wang, Z. C.; Xu, Y. T.; Yang, F.; Wang, B. S.; Gao, H. W.; Bo, Y.; Peng, Q. J.; Cui, D. F.; Xu, Z. Y.

    2010-07-01

    We demonstrate a high power continuous wave (CW) infrared laser operated at 1112 nm from a diode side-pumped Nd:YAG crystal with a plano-plano symmetrical resonator. By inserting an etalon, an output power of as high as 93.7 W at 1112 nm was obtained at the pump power of 570 W with conversion efficiency of 16.4%. The beam quality factor of M2 was measured to be about 17. The wavelength tunable performance of the etalon was also analyzed. To the best of our knowledge, it is the highest output power at 1112 nm CW laser based on Nd:YAG crystal.

  20. Design optical antenna and fiber coupling system based on the vector theory of reflection and refraction.

    PubMed

    Jiang, Ping; Yang, Huajun; Mao, Shengqian

    2015-10-01

    A Cassegrain antenna system and an optical fiber coupling system which consists of a plano-concave lens and a plano-convex lens are designed based on the vector theory of reflection and refraction, so as to improve the transmission performance of the optical antenna and fiber coupling system. Three-dimensional ray tracing simulation are performed and results of the optical aberrations calculation and the experimental test show that the aberrations caused by on-axial defocusing, off-axial defocusing and deflection of receiving antenna can be well corrected by the optical fiber coupling system. PMID:26480125

  1. A Mixed Methods Portrait of Urban Instrumental Music Teaching

    ERIC Educational Resources Information Center

    Fitzpatrick, Kate R.

    2011-01-01

    The purpose of this mixed methods study was to learn about the ways that instrumental music teachers in Chicago navigated the urban landscape. The design of the study most closely resembles Creswell and Plano Clark's (2007) two-part Triangulation Convergence Mixed Methods Design, with the addition of an initial exploratory focus group component.…

  2. Educational Multimedia Implementation in Schools: Producer-Teacher-Student Links.

    ERIC Educational Resources Information Center

    Henderson, Lyn; Eshet, Yoram; Klemes, Joel

    This paper presents findings demonstrating benefits of cooperation between Edunetics, a commercial multimedia production company, and the Plano Independent School District (Texas) that resulted in a unique curriculum integration project. The "Message in a Fossil" (MIF) simulation software was used with three pairs of second grade students; data…

  3. Implementation of an Education Technology Policy in Namibia's High Schools: Through the Eyes of the Teacher

    ERIC Educational Resources Information Center

    Boer, Perien Joniell

    2012-01-01

    The purpose of this study was to explore how Namibian high school teachers experienced the ICT policy for education in their schools. This mixed methods sequential explanatory design consists of two distinct phases: quantitative followed by qualitative (Creswell & Plano Clark, 2011). Quantitative data collection involved the distribution and…

  4. A multiplex real-time polymerase chain reaction assay differentiates between Bolbphorus damnificus and Bolbophorus type II sp

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A duplex quantitative real-time polymerase chain reaction (qPCR) assay was developed to differentiate between Bolbophorus damnificus and Bolbophorus type II species cercariae. Both trematode species are prevalent throughout the commercial catfish industry,.as both infect the ram’s horn snail, Plano...

  5. Building the Foundation

    ERIC Educational Resources Information Center

    Brooks, Marilyn

    2006-01-01

    In this column, the author shares some of the processes involved with the restructuring of the elementary curriculum and the role of technology in the classroom. When Plano ISD committed time, talent, and technology to a new educational vision, the Elementary Integrated Curriculum project was born. The goal: to integrate subject matter and…

  6. From the Pinhole Camera to the Shape of a Lens: The Camera-Obscura Reloaded

    ERIC Educational Resources Information Center

    Ziegler, Max; Priemer, Burkhard

    2015-01-01

    We demonstrate how the form of a plano-convex lens and a derivation of the thin lens equation can be understood through simple physical considerations. The basic principle is the extension of the pinhole camera using additional holes. The resulting images are brought into coincidence through the deflection of light with an arrangement of prisms.…

  7. 78 FR 72865 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    .... (``AIA'') original Certificate was issued on September 8, 1992 (57 FR 41920, September 14, 1992). A... Corporation, Toronto, Canada CERTON Software, Inc., Melbourne, FL Chromalloy, San Antonio, TX Click Bond, Inc... Siemens PLM Software, Plano, TX Sierra Nevada Corporation, Space Systems, Littleton, CO SIFCO...

  8. RFID Student Educational Experiences at the UNT College of Engineering: A Sequential Approach to Creating a Project-Based RFID Course

    ERIC Educational Resources Information Center

    Vaidyanathan, V. V.; Varanasi, M. R.; Kougianos, E.; Wang, Shuping; Raman, H.

    2009-01-01

    This paper describes radio frequency identification (RFID) projects, designed and implemented by students in the College of Engineering at the University of North Texas, as part of their senior-design project requirement. The paper also describes an RFID-based project implemented at Rice Middle School in Plano, TX, which went on to win multiple…

  9. On a Different "Plane": Cross-Language Effects on the Conceptual Representations of Within-Language Homonyms

    ERIC Educational Resources Information Center

    Areas Da Luz Fontes, Ana B.; Schwartz, Ana I.

    2010-01-01

    We examined whether bilinguals' conceptual representation of homonyms in one language are influenced by meanings in the other. One hundred and seventeen Spanish-English bilinguals generated sentences for 62 English homonyms that were also cognates with Spanish and which shared at least one meaning with Spanish (e.g., plane/"plano"). Production…

  10. Data-Driven Decision-Making: Mission Accomplished

    ERIC Educational Resources Information Center

    Weinstock, Jeff

    2009-01-01

    When the author and his colleagues last left Chicago Public Schools (CPS) and Texas' Plano Independent School District in April 2008, both school districts were immersed in the long and labored advance toward becoming a fully matured data-driven operation, one that uses sophisticated technologies to gather data, sort and interpret it, and…

  11. On the Road to DDDM

    ERIC Educational Resources Information Center

    Schaffhauser, Dian

    2008-01-01

    Two school districts--Chicago Public Schools (CPS) and Plano Independent School District in Texas--have undertaken ambitious initiatives in recent years to introduce data-driven decision-making into their operations. Although each has struggled with different obstacles, both have progressed beyond the initial two stages on the DDDM continuum,…

  12. Compare and Contrast Inductive and Deductive Research Approaches

    ERIC Educational Resources Information Center

    Soiferman, L. Karen

    2010-01-01

    This discussion paper compares and contrasts "inductive" and "deductive" research approaches as described by Trochim (2006) and Plano Clark and Creswell (2007). It also examines the "exploratory" and "confirmatory" approaches by Onwueghuzie and Leech (2005) with respect to the assumption each holds about the nature of knowledge. The paper starts…

  13. Microbiological water examination during laboratory courses generates new knowledge for students, scientists and the government.

    PubMed

    Svanevik, Cecilie Smith; Lunestad, Bjørn Tore

    2015-10-01

    Contaminated water is globally the main vehicle for microbial pathogens in most regions. Teaching future microbiologist and employees in the food industry on the importance of hygienically satisfactory water, microbiological analyses and how to ensure good water quality and safety is highly relevant. This paper presents a complete experimental design for water analyses as a tool to teach students the methods and other key elements in microbiology, including food safety, environmental dissemination and survival of microorganisms, laboratory practices, water legislation and critical evaluation of results. All results from the last 10 classes (2006-2015) in a university course on seafood microbiology have been compiled and are presented here. Questionnaires used with former students reveal that the laboratory course is highly appreciated, and that many students remember important aspects of the water analyses, even after several years. The questionnaire results were consistent with our perception that some students find calculation of dilutions difficult to comprehend. PMID:26337153

  14. Evolutionary features of influenza A/H5N1 virus populations in Egypt: poultry and human health implications.

    PubMed

    Naguib, Mahmoud M; Abdelwhab, E M; Harder, Timm C

    2016-07-01

    Since 2006, in Egypt, highly pathogenic avian influenza virus (HPAIV) H5N1 has established endemic status in poultry. Bayesian evolutionary analysis sampling trees suggested an introduction date in the third quarter of 2005. Evolutionary dynamics using Bayesian analysis showed that H5N1 viruses of clade 2.2.1.1 evolved at higher rates than those of clade 2.2.1.2. Bayesian skyline plot analysis of the HA gene of 840 and NA gene of 401 Egyptian H5N1 viruses from 2006-2015 identified two waves of viral population expansion correlating with the stepwise emergence of the 2.2.1.1 variant lineage in 2008 and with the newly emerging 2.2.1.2 cluster in late 2014. H5N1 infections in human hosts in 2014-2015 were statistically linked to a contemporary poultry outbreak. PMID:27068161

  15. Multidimensional Analysis and Location Intelligence Application for Spatial Data Warehouse Hotspot in Indonesia using SpagoBI

    NASA Astrophysics Data System (ADS)

    Uswatun Hasanah, Gamma; Trisminingsih, Rina

    2016-01-01

    Spatial data warehouse refers to data warehouse which has a spatial component that represents the geographic location of the position or an object on the Earth's surface. Spatial data warehouse can be visualized in the form of a crosstab tables, graphs, and maps. Spatial data warehouse of hotspot in Indonesia has been constructed by researchers from FIRM NASA 2006-2015. This research develops multidimensional analysis module and location intelligence module using SpagoBI. The multidimensional analysis module is able to visualize online analytical processing (OLAP). The location intelligence module creates dynamic map visualization in map zone and map point. Map zone can display the different colors based on the number of hotspot in each region and map point can display different sizes of the point to represent the number of hotspots in each region. This research is expected to facilitate users in the presentation of hotspot data as needed.

  16. Regeneration, relocation and health behaviours in deprived communities.

    PubMed

    Kearns, Ade; Mason, Phil

    2015-03-01

    In the UK, recent regeneration programmes have aimed to improve the health of those who remain in their neighbourhood (Remainers) and those who are relocated (Outmovers); thus, as part of the 10-year GoWell study (2006-2015) of the effects of demolition, rebuilding and housing improvements on residents and communities, we examined associations of health behaviours with residential conditions and location status in deprived neighbourhoods of Glasgow. Better internal dwelling conditions were associated with several better health behaviours; in relation to neighbourhood conditions, the results were more mixed. Outmovers often exhibited worse health behaviours than Remainers, perhaps because environmental and social conditions were little altered by relocation, and because personal support mechanisms were missing. Health behaviours were relatively good among Remainers, indicating that in situ changes might stimulate life-changing improvements, but relocation less so. PMID:25618564

  17. Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry.

    PubMed

    De Pinho, P Guedes; Gonçalves, Rui F; Valentão, Patrícia; Pereira, David M; Seabra, Rosa M; Andrade, Paula B; Sottomayor, Mariana

    2009-04-01

    A total of 88 volatile and semi-volatile components were formally or tentatively identified in flowers, leaves and stems of Catharanthus roseus (L.) G. Don (cv. Little Bright Eye), by headspace solid-phase microextraction (HS-SPME) and by dichloromethane extraction, combined with gas chromatography-mass spectrometry (GC-MS). These include some diterpenic compounds (manool and manoyl oxides), a sesquiterpen (alpha-bisabolol), and some pyridine, pyrazine, indol and carotenoid derivatives. Applying multivariate analysis (principal component analysis and agglomerative hierarchic cluster analysis) to the HS-SPME-GC-MS data, it was possible to characterize each part of the vegetal material using a relative small number of compounds. Hence, flowers were richer in terpenic molecules (including limonene), alpha-bisabolol, methyljasmonate, cis-jasmone, 2-phenylethanol, phenylacetaldehyde, trans-2-octenal, benzylic alcohol and 2-isobutyl-3-methoxypyrazine. Leaves can be characterized by the methyl and propyl esters of fatty acids, mono- and disaturated, trans-phytol, carotenoid derivative compounds, hydrofarnesylacetone, methylanthranilate, manool and epi-manool oxide, while stems have high levels of volatile aldehydes, such as hexanal, octanal, cis-2-nonenal, cis-2-decenal, cis, trans-2,6-nonadienal, trans, trans-2,4-decadienal and cis, trans-2,4-decadienal. Dichloromethane extraction allowed also the identification of some alkaloid-like compounds that were not detected by HS-SPME. PMID:19186019

  18. Modulation of flat-band voltage on H-terminated silicon-on-insulator pseudo-metal-oxide-semiconductor field effect transistors by adsorption and reaction events

    NASA Astrophysics Data System (ADS)

    Dubey, Girjesh; Rosei, Federico; Lopinski, Gregory P.

    2011-05-01

    Accumulation mode pseudo-MOSFETs formed on hydrogen terminated silicon-on-insulator (SOI-H) were used to probe molecular adsorption and reaction events. Current-voltage characteristics of such n-channel devices are found to be sensitive to the environment, with the accumulation threshold voltage, or flat-band voltage, exhibiting large reversible changes upon cycling between ambient atmosphere, high vacuum (<10-5 Torr), and exposure to water and pyridine vapor at pressures in the Torr range. The field-effect mobility is found to be comparatively less affected through these transitions. Oxidation of the H-terminated surface in ambient conditions leads to irreversible shifts in both the flat-band voltage and the field-effect mobility. A photochemical gas phase reaction with decene is used to form a decyl monolayer on the SOI(100)-H surface. Formation of this monolayer is found to result in a relatively small shift of the threshold voltage and only a slight degradation of the field effect mobility, suggesting that alkyl monolayer dielectrics formed in this way could function as good passivating dielectrics in field effect sensing applications.

  19. Identification and biotransformation of aliphatic hydrocarbons during co-composting of sewage sludge-Date Palm waste using Pyrolysis-GC/MS technique.

    PubMed

    El Fels, Loubna; Lemee, Laurent; Ambles, André; Hafidi, Mohamed

    2016-08-01

    The behavior of aliphatic hydrocarbons during co-composting of sewage sludge activated with palm tree waste was studied for 6 months using Py-GC/MS. The main aliphatic compounds represented as doublet alkenes/alkanes can be classified into three groups. The first group consists of 11 alkenes (undecene, tridecene, pentadecene, hexadecene, heptadecene, octadecene, nonadecene, eicosene, uncosene, docosene, tricosene) and 15 alkanes (heptane, octane, nonane, decane, undecane, dodecane, tetradecane, pentadecane, heptadecane, octadecane, nonadecane, eicosane, uncosane, docosane, and tricosane), which remain stable during the co-composting process. The stability of these compounds is related to their recalcitrance behavior. The second group consists of five alkenes (heptene, octene, nonene, decene, dodecene) and tridecane as a single alkane that decreases during co-composting. The decrease in these compounds is the combined result of their metabolism and their conversion into other compounds. The third group is constituted with tetradecene and hexadecane that increase during composting, which could be explained by accumulation of these compounds, which are released by the partial breakdown of the substrate. As a result, these molecules are incorporated or adsorbed in the structure of humic substances. PMID:27197656

  20. Epidemiology of tree-hole breeding mosquitoes in the tropical rainforest of Imo State, south-east Nigeria.

    PubMed

    Anosike, Jude C; Nwoke, Bertram E B; Okere, Anthony N; Oku, Ene E; Asor, Joe E; Emmy-Egbe, Ifeyinwa O; Adimike, Desmond A

    2007-01-01

    The study of tree-hole breeding mosquitoes was carried out in the tropical rainforest of Imo State Nigeria (two rural areas and two forest reserves in some parts of Orlu Senatorial Zone) between May-October 2002. Using standard entomological procedures, two macrohabitats (natural tree-holes and bamboo traps) and two microhabitats (leaf axils of cocoyams/pineapples and leaf axils of plantain/banana) were sampled for various mosquito species. Mosquitoes were recovered from all the various biotypes sampled. Types of mosquitoes species encountered, their relative abundance, as well as genera varied significantly during the study (p<0.05). Four genera of mosquitoes: Aedes, Culex, Anopheles and Toxorhynchites were recovered while 16 species of mosquitoes encountered include: Aedes aegypti, Ae. africanus, Ae. simpsoni, Ae. albopictus, Ae. stokesi, Ae. taylori, Ae. apicoargenteus, Culex quinquefasciatus, Cx. nebulosus, Cx. trigripes, Cx. decens, Anopheles gambiae, An. funiestus, An. coustani and Toxorhynchites viridibasis. Most of the mosquitoes showed oviposition preferences for one or more habitats. The presence of Ae. africanus, Ae. simpsoni and Ae. aegypti indicate that the study areas were at risk of yellow fever epidemic. The presence of Anopheles and Culex species ensured endemicity of malaria and filariasis, while the recovery of Ae. albopictus in this region suggests a possible outbreak of dengue fever in future if not properly controlled. PMID:17655174

  1. Aroma components of American country ham.

    PubMed

    Song, H; Cadwallader, K R

    2008-01-01

    The aroma-active compounds of American country ham were investigated by using direct solvent extraction-solvent assisted flavor evaporation (DSE-SAFE), dynamic headspace dilution analysis (DHDA), gas chromatography-olfactometry (GCO), aroma extract dilution analysis (AEDA), and gas chromatography-mass spectrometry (GC-MS). The results indicated the involvement of numerous volatile constituents in the aroma of country ham. For DHDA, 38 compounds were identified as major odorants, among them, 1-octen-3-one, 2-acetyl-1-pyrroline, 1-nonen-3-one, decanal, and (E)-2-nonenal were the most predominant, having FD-factors >or= 125 in all 3 hams examined, followed by 3-methylbutanal, 1-hexen-3-one, octanal, acetic acid, phenylacetaldehyde, and Furaneol. For the DSE-SAFE method, the neutral/basic fraction was dominated by 1-octen-3-one, methional, guaiacol, (E)-4,5-epoxy-(E)-decenal, p-cresol as well as 3-methylbutanal, hexanal, 2-acetyl-1-pyrroline, phenylacetaldehyde, and gamma-nonalactone. The acidic fraction contained mainly short-chain volatile acids (3-methylbutanoic acid, butanoic acid, hexanoic acid, and acetic acid) and Maillard reaction products (for example, 4-hydroxy-2,5-dimethyl-3(2H)-furanone). The above compounds identified were derived from lipid oxidation, amino acid degradation, and Maillard/Strecker and associated reactions. Both methods revealed the same nature of the aroma components of American country ham. PMID:18211346

  2. Common gas phase molecules from fungi affect seed germination and plant health in Arabidopsis thaliana

    PubMed Central

    2014-01-01

    Fungal volatile organic compounds (VOCs) play important ecophysiological roles in mediating inter-kingdom signaling with arthropods but less is known about their interactions with plants. In this study, Arabidopsis thaliana was used as a model in order to test the physiological effects of 23 common vapor-phase fungal VOCs that included alcohols, aldehydes, ketones, and other chemical classes. After exposure to a shared atmosphere with the 23 individual VOCs for 72 hrs, seeds were assayed for rate of germination and seedling formation; vegetative plants were assayed for fresh weight and chlorophyll concentration. All but five of the VOCs tested (1-decene, 2-n-heptylfuran, nonanal, geosmin and -limonene) had a significant effect in inhibiting either germination, seedling formation or both. Seedling formation was entirely inhibited by exposure to 1-octen-3-one, 2-ethylhexanal, 3-methylbutanal, and butanal. As assayed by a combination of fresh weight and chlorophyll concentration, 2-ethylhexanal had a negative impact on two-week-old vegetative plants. Three other compounds (1-octen-3-ol, 2-ethylhexanal, and 2-heptylfuran) decreased fresh weight alone. Most of the VOCs tested did not change the fresh weight or chlorophyll concentration of vegetative plants. In summary, when tested as single compounds, fungal VOCs affected A. thaliana in positive, negative or neutral ways. PMID:25045602

  3. Headspace solid-phase microextraction with on-fiber derivatization for the determination of aldehydes in algae by gas chromatography-mass spectrometry.

    PubMed

    Ma, Jiping; Xiao, Ronghui; Li, Jinhua; Li, Jie; Shi, Benzhang; Liang, Yanjuan; Lu, Wenhui; Chen, Lingxin

    2011-06-01

    A simple, fast, sensitive and cost-effective method based on headspace solid-phase microextraction (HS-SPME) with on-fiber derivatization coupled with gas chromatography-mass spectrometry was developed for the determination of six typical aldehydes, 2E-hexenal, heptanal, 2E-heptenal, 2E,4E-heptadienal, 2E-decenal and 2E,4E-decadienal in laboratory algae cultures. As derivatization reagent, O-2,3,4,5,6-(pentafluorobenzyl) hydroxylamine hydrochloride, was loaded onto the poly(dimethylsiloxane)/divinylbenzene fiber for aldehydes on-fiber derivatization prior to HS-SPME. Various influence factors of extraction efficiency were systematically investigated. Under optimized extraction conditions, excellent method performances for all the six aldehydes were attained, such as satisfactory extraction recoveries ranging from 67.1 to 117%, with the precision (relative standard deviation) within 5.3-11.1%, and low detection limits in the range of 0.026-0.044 μg/L. The validated method was successfully applied for the analysis of the aldehydes in two diatoms (Skeletonema costatum and Chaetoceros muelleri), two pyrrophytas (Prorocentrum micans and Scrippsiella trochoidea) and Calanus sinicus eggs (feeding on the two diatoms above). PMID:21567947

  4. Unveiling chemical defense in the rice stalk stink bug against the entomopathogenic fungus Metarhizium anisopliae.

    PubMed

    da Silva, Rodrigo Alves; Quintela, Eliane Dias; Mascarin, Gabriel Moura; Pedrini, Nicolás; Lião, Luciano Moraes; Ferri, Pedro Henrique

    2015-05-01

    Eggs, nymphs (1st-5th instar) and adults of Tibraca limbativentris were challenged by conidial suspensions of its major fungal pathogen Metarhizium anisopliae in order to assess their susceptibility. The role of chemical defensive compounds from exocrine secretions produced by both nymphs and adults were examined for their participation on M. anisopliae infection. Although insect susceptibility to M. anisopliae followed a dose-dependent manner, adults followed by older nymphs displayed the highest resistance. Eggs were highly susceptible showing >96% fungal infection. Crude extracts isolated from metathoracic scent gland and dorsal abdominal glands of adults and nymphs, respectively, showed fungistatic effects by impairing spore germination, vegetative growth and sporulation. Gas chromatography-mass spectrometry analysis of these extracts revealed that the major components were short-chain hydrocarbons (C10-13) and unsaturated aldehydes. In vitro tests with the corresponding synthetic standards indicated compounds with greater antifungal activity including (E)-2-hexenal, (E)-2-octenal, and (E)-2-decenal, with the latter being the most deleterious to fungal fitness. We demonstrated that differential susceptibility of the rice stalk stink bug to M. anisopliae infection is age-specific and partly mediated by fungistatic properties of aldehydes, which are produced by scent glands of both nymphs and adults. PMID:25805519

  5. Volatile profile of cashew apple juice fibers from different production steps.

    PubMed

    Nobre, Ana Carolina de Oliveira; de Almeida, Áfia Suely Santos da Silva; Lemos, Ana Paula Dajtenko; Magalhães, Hilton César Rodrigues; Garruti, Deborah dos Santos

    2015-01-01

    This study aimed to determine the volatile profile of cashew apple fibers to verify which compounds are still present after successive washings and thus might be responsible for the undesirable remaining cashew-like aroma present in this co-product, which is used to formulate food products like vegetarian burgers and cereal bars. Fibers were obtained from cashew apple juice processing and washed five times in an expeller press. Compounds were analyzed by the headspace solid-phase micro extraction technique (HS-SPME) and gas chromatography-mass spectrometry (GC-MS), using a DB-5 column. Sensory analysis was also performed to compare the intensity of the cashew-like aroma of the fibers with the original juice. Altogether, 80 compounds were detected, being esters and terpenes the major chemical classes. Among the identified substances, 14 were classified as odoriferous in the literature, constituting the matrix used in the Principal Component Analysis (PCA). Odoriferous esters were substantially reduced, but many compounds were extracted by the strength used in the expeller press and remained until the last wash. Among them are the odoriferous compounds ethyl octanoate, γ-dodecalactone, (E)-2-decenal, copaene, and caryophyllene that may contribute for the mild but still perceptible cashew apple aroma in the fibers that have been pressed and washed five times. Development of a deodorization process should include reduction of pressing force and stop at the second wash, to save water and energy, thus reducing operational costs and contributing to process sustainability. PMID:26023940

  6. Synthesis, structural characterization and catalytic activity of a multifunctional enzyme mimetic oxoperoxovanadium(V) complex.

    PubMed

    Si, Tapan K; Paul, Shiv S; Drew, Michael G B; Mukherjea, Kalyan K

    2012-05-21

    The synthesis and structural characterization of a novel oxoperoxovanadium(V) complex [VO(O(2))(PAH)(phen)] containing the ligands 2-phenylacetohydroxamic acid (PAHH) and 1,10-phenanthroline (phen) has been accomplished. The oxoperoxovanadium(V) complex was found to mimic both vanadate-dependent haloperoxidase (VHPO) activity as well as nuclease activity through effective interaction with DNA. The complex is the first example of a structurally characterized stable oxoperoxovanadium(V) complex with a coordinated bi-dentate hydroximate moiety (-CONHO(-)) from 2-phenylacetohydroximate (PAH). The oxoperoxovanadium(V) complex has been used as catalyst for the peroxidative bromination reaction of some unsaturated alcohols (e.g. 4-pentene-1-ol, 1-octene-3-ol and 9-decene-1-ol) in the presence of H(2)O(2) and KBr. The catalytic products have been characterized by GC-MS analysis and spectrophotometric methods. The DNA binding of this complex has been established with CT DNA whereas the DNA cleavage was demonstrated with plasmid DNA. The interactions of the complex with DNA have been monitored by electronic absorption and fluorescence emission spectroscopy. Viscometric measurements suggest that the compound is a DNA intercalator. The nuclease activity of this complex was confirmed by gel electrophoresis studies. PMID:22441646

  7. Anti-biofilm and anti-adherence activities of sub fraction 18 of Melastoma malabathricum towards Streptococcus mutans

    NASA Astrophysics Data System (ADS)

    Rohazila M., H.; Nazlina, I.; Yaacob W., A.

    2014-09-01

    A study was carried out to isolate and identify the active compounds from Melastoma malabathricum stem bark that exhibit anti-biofilm and anti-adherence activities against Streptococcus mutans. Purification of the active compounds from the stem bark extract was performed via silica gel chromatography to produce 12 fractions. Further fractionation of fraction 9 by high performance liquid chromatography (HPLC) produced 21 sub fractions. All the sub fractions were subjected to thin layer chromatography (TLC) bioautography as preliminary screening to determine anti bacterial activity. TLC-bioautography showed that sub fraction 18 (SF18) demonstrated large inhibited zone against S. mutans. Gas chromatography mass spectrometry (GCMS) was used to identify the active compounds in SF18. Fraction SF18 revealed 27 compounds such as hexanoic acid, 8-methyl-1-undecene, propanenitrile, and 1-decene. Anti-biofilm and anti-adherence activities were determined using crystal violet and glass surface assays respectively. The concentrations that produced 50% reduction in anti-biofilm and anti-adherence activities were 1.88 mg/ml and 3.75 mg/ml respectively.

  8. Biodiversity of volatile organic compounds from five French ferns.

    PubMed

    Fons, Françoise; Froissard, Didier; Bessière, Jean-Marie; Buatois, Bruno; Rapior, Sylvie

    2010-10-01

    Five French ferns belonging to different families were investigated for volatile organic compounds (VOC) by GC-MS using organic solvent extraction. Fifty-five VOC biosynthesized from the shikimic, lipidic and terpenic pathways including monoterpenes, sesquiterpenes and carotenoid-type compounds were identified. The main volatile compound of Adiantum capillus-veneris L. (Pteridaceae) was (E)-2-decenal with a plastic or "stink bug" odor. The volatile profiles of Athyrium filix-femina (L.) Roth (Woodsiaceae) and Blechnum spicant (L.) Roth (Blechnaceae) showed similarities, with small amounts of isoprenoids and the same main volatile compounds, i.e., 2-phenylethanal (odor of lilac and hyacinth) and 1-octen-3-ol (mushroom-like odor). The main volatile compound of Dryopteris filix-mas (L.) Schott (Dryopteridaceae) was (E)-nerolidol with a woody or fresh bark note. Polyketides, as acylfilicinic acids, were mainly identified in this fern. Oreopteris limbosperma (Bellardi ex. All.) J. Holub (Thelypteridaceae), well-known for its lemon smell, contained the highest biodiversity of VOC. Eighty percent of the volatiles was issued from the terpenic pathway. The main volatiles were (E)-nerolidol, alpha-terpineol, beta-caryophyllene and other minor monoterpenes (for example, linalool, pinenes, limonene, and gamma-terpinen-7-al). It was also the fern with the highest number of carotenoid-type derivatives, which were identified in large amounts. Our results were of great interest underlying new industrial valorisation for ferns based on their broad spectrum of volatiles. PMID:21121267

  9. Substrate range and enantioselectivity of epoxidation reactions mediated by the ethene-oxidising Mycobacterium strain NBB4.

    PubMed

    Cheung, Samantha; McCarl, Victoria; Holmes, Andrew J; Coleman, Nicholas V; Rutledge, Peter J

    2013-02-01

    Mycobacterium strain NBB4 is an ethene-oxidising micro-organism isolated from estuarine sediments. In pursuit of new systems for biocatalytic epoxidation, we report the capacity of strain NBB4 to convert a diverse range of alkene substrates to epoxides. A colorimetric assay based on 4-(4-nitrobenzyl)pyridine) has been developed to allow the rapid characterisation and quantification of biocatalytic epoxide synthesis. Using this assay, we have demonstrated that ethene-grown NBB4 cells epoxidise a wide range of alkenes, including terminal (propene, 1-butene, 1-hexene, 1-octene and 1-decene), cyclic (cyclopentene, cyclohexene), aromatic (styrene, indene) and functionalised substrates (allyl alcohol, dihydropyran and isoprene). Apparent specific activities have been determined and range from 2.5 to 12.0 nmol min(-1) per milligram of cell protein. The enantioselectivity of epoxidation by Mycobacterium strain NBB4 has been established using styrene as a test substrate; (R)-styrene oxide is produced in enantiomeric excesses greater than 95%. Thus, the ethene monooxygenase of Mycobacterium NBB4 has a broad substrate range and promising enantioselectivity, confirming its potential as a biocatalyst for alkene epoxidation. PMID:22410742

  10. Characterization of Key Aroma Compounds in Raw and Thermally Processed Prawns and Thermally Processed Lobsters by Application of Aroma Extract Dilution Analysis.

    PubMed

    Mall, Veronika; Schieberle, Peter

    2016-08-24

    Application of aroma extract dilution analysis (AEDA) to an aroma distillate of blanched prawn meat (Litopenaeus vannamei) (BPM) revealed 40 odorants in the flavor dilution (FD) factor range from 4 to 1024. The highest FD factors were assigned to 2-acetyl-1-pyrroline, 3-(methylthio)propanal, (Z)-1,5-octadien-3-one, trans-4,5-epoxy-(E)-2-decenal, (E)-3-heptenoic acid, and 2-aminoacetophenone. To understand the influence of different processing conditions on odorant formation, fried prawn meat was investigated by means of AEDA in the same way, revealing 31 odorants with FD factors between 4 and 2048. Also, the highest FD factors were determined for 2-acetyl-1-pyrroline, 3-(methylthio)propanal, and (Z)-1,5-octadien-3-one, followed by 4-hydroxy-2,5-dimethyl-3(2H)-furanone, (E)-3-heptenoic acid, and 2-aminoacetophenone. As a source of the typical marine, sea breeze-like odor attribute of the seafood, 2,4,6-tribromoanisole was identified in raw prawn meat as one of the contributors. Additionally, the aroma of blanched prawn meat was compared to that of blanched Norway and American lobster meat, respectively (Nephrops norvegicus and Homarus americanus). Identification experiments revealed the same set of odorants, however, with differing FD factors. In particular, 3-hydroxy-4,5-dimethyl-2(5H)-furanone was found as the key aroma compound in blanched Norway lobster, whereas American lobster contained 3-methylindole with a high FD factor. PMID:27486834

  11. In depth study of acrylamide formation in coffee during roasting: role of sucrose decomposition and lipid oxidation.

    PubMed

    Kocadağlı, Tolgahan; Göncüoğlu, Neslihan; Hamzalıoğlu, Aytül; Gökmen, Vural

    2012-09-01

    Coffee, as a source of acrylamide, needs to be investigated in depth to understand the contribution of different precursors. This study aimed to investigate the contributions of sucrose decomposition and lipid oxidation on acrylamide formation in coffee during roasting. Coffee beans and model systems were used to monitor the accumulation of neo-formed carbonyls during heating through sucrose decomposition and lipid oxidation. High resolution mass spectrometry analyses confirmed the formation of 5-hydroxymethylfurfural (HMF) and 3,4-dideoxyosone, which were identified as the major sugar decomposition products in both roasted coffee and model systems. Among others, 2-octenal, 2,4-decadienal, 2,4-heptadienal, 4-hydroxynonenal, and 4,5-epoxy-2-decenal were identified in relatively high quantities in roasted coffee. Formation and elimination of HMF in coffee during roasting had a kinetic pattern similar to those of acrylamide. Its concentration rapidly increased within 10 min followed by an exponential decrease afterward. The amount of lipid oxidation products tended to increase linearly during roasting. It was concluded from the results that roasting formed a pool of neo-formed carbonyls from sucrose decomposition and lipid oxidation, and they play certain role on acrylamide formation in coffee. PMID:22796869

  12. New Anthraquinone Derivatives from Geosmithia lavendula

    PubMed Central

    Malak, Lourin G.; Bishay, Daoud W.; Abdel-Baky, Afaf M.; Moharram, Ahmed M.; Cutler, Stephen J.; Ross, Samir A.

    2016-01-01

    A phytochemical study of Geosmithia lavendula Pitt led to the isolation of three new anthraquinones: 1-acetyl-2,4,6,8-tetrahydroxy-9,10-anthraquinone (1), 2-acetyl-1,4,5,7-tetrahydroxy-9,10-anthraquinone (2), and 1-acetyl-2,4,5,6,7-pentahydroxy-9,10-anthraquinone (3), as well as another new compound named didodecyl thiodipropionate (propionic acid, 3,3-sulfinyl di-1,1′-didodecyl ester) (4), along with ten known compounds: 1-acetyl-2,4,5,7-tetrahydroxy-9,10-anthraquinone (rhodolamprometrin) (5), 1-acetyl-2,4,5,7,8-pentahydroxy-9,10-anthraquinone (6), (22E)-ergosta-6,22-diene-3β,5α,8α-triol, p-hydroxybenzyl alcohol, oleic acid, D-mannitol, palmitic acid, stearic acid, cis-vaccenic acid and 2-decenal. The structures of the isolated metabolites were elucidated based on NMR spectroscopic and mass spectrometric data. Compound 1 exhibited moderate activity against methicillin resistant Staphylococcus aureus with an IC50 value of 16.1 μg/mL. PMID:23513726

  13. Preparation of ansa-metallocenes for production of poly(α-olefin) lubricants.

    PubMed

    Park, Ji Hae; Jang, Young Eun; Jeon, Jong Yeob; Go, Min Jeong; Lee, Junseong; Kim, Sung Kwan; Lee, Sang-Ick; Lee, Bun Yeoul

    2014-07-14

    An ansa-zirconocene bearing methyl substituents at all positions adjacent to the bridgehead [(-C(Ph)HC(Ph)H-)(η(5)-2,5-Me2C5H2)2ZrCl2] (4) was prepared in high yields (78%) through the reductive dimerization of 1,4-dimethyl-6-phenylfulvene utilizing ZrCl2·DME generated in situ. The structure of 4 was subsequently confirmed using X-ray crystallography. 4 exhibited excellent catalytic performance with regard to 1-decene oligomerization, which was carried out with the intention of preparing lubricant base stocks. High activities (21 × 10(6) g mol(-1) Zr h(-1) activity; TON = 150 000; TOF = 42 s(-1)) were observed at temperatures as high as 120 °C and the oligomer distribution was appropriate for lubricant application. The simulated distillation (SIMDIS) data confirmed that a wide range of oligomers were formed, ranging from the dimer (2-mer) to 20-mer. A minimal amount of the dimer and oligomers larger than the 10-mer was formed (13 and 25 wt%, respectively). Alternatively, a typical unbridged complex such as (η(5)-nBuC5H4)2ZrCl2 primarily produced dimers (54 wt%), whereas the ansa-zirconocene (EBI)ZrCl2 primarily produced oligomers larger than 10-mer (62 wt%). The methyl substituents at the positions adjacent to the bridgehead in 4 played a significant role in the catalytic performance. PMID:24875269

  14. Evaluation of certain food additives and contaminants.

    PubMed

    2002-01-01

    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives and contaminants, with a view to recommending Acceptable Daily Intakes (ADIs) and tolerable intakes, respectively, and to prepare specifications for the identity and purity of food additives. The first part of the report contains a general discussion of the principles governing the toxicological evaluation of food additives (including flavouring agents) and contaminants, assessments of intake, and the establishment and revision of specifications for food additives. A summary follows of the Committee's evaluations of toxicological and intake data on various specific food additives (diacetyltartaric and fatty acid esters of glycerol, quillaia extracts, invertase from Saccharomyces cerevisiae, beta-carotene from Blakeslea trispora, curcumin, phosphates, diphosphates and polyphosphates, hydrogenated poly-1-decene, natamycin, D-tagatose, carrageenan, processed Eucheuma seaweed, curdlan, acetylated oxidized starch, alpha-cyclodextrin and sodium sulfate), flavouring agents and contaminants (3-chloro-1,2-propanediol, 1,3-dichloro-2-propanol, and a large number of polychlorinated dibenzodioxins, polychlorinated dibenzofurans and coplanar polychlorinated biphenyls). Annexed to the report are tables summarizing the Committee's recommendations for ADIs of the food additives and tolerable intakes of the contaminants considered, changes in the status of specifications of these food additives and specific flavouring agents, and further information required or desired. PMID:12564044

  15. Arbuscular mycorrhizal fungi associated with Artemisia umbelliformis Lam, an endangered aromatic species in Southern French Alps, influence plant P and essential oil contents.

    PubMed

    Binet, Marie-Noëlle; van Tuinen, Diederik; Deprêtre, Nicolas; Koszela, Nathalie; Chambon, Catherine; Gianinazzi, Silvio

    2011-08-01

    Root colonization by arbuscular mycorrhizal (AM) fungi of Artemisia umbelliformis, investigated in natural and cultivated sites in the Southern Alps of France, showed typical structures (arbuscules, vesicles, hyphae) as well as spores and mycelia in its rhizosphere. Several native AM fungi belonging to different Glomeromycota genera were identified as colonizers of A. umbelliformis roots, including Glomus tenue, Glomus intraradices, G. claroideum/etunicatum and a new Acaulospora species. The use of the highly mycorrhizal species Trifolium pratense as a companion plant impacted positively on mycorrhizal colonization of A. umbelliformis under greenhouse conditions. The symbiotic performance of an alpine microbial community including native AM fungi used as inoculum on A. umbelliformis was evaluated in greenhouse conditions by comparison with mycorrhizal responses of two other alpine Artemisia species, Artemisia glacialis and Artemisia genipi Weber. Contrary to A. genipi Weber, both A. umbelliformis and A. glacialis showed a significant increase of P concentration in shoots. Volatile components were analyzed by GC-MS in shoots of A. umbelliformis 6 months after inoculation. The alpine microbial inoculum increased significantly the percentage of E-β-ocimene and reduced those of E-2-decenal and (E,E)-2-4-decadienal indicating an influence of alpine microbial inoculum on essential oil production. This work provides practical indications for the use of native AM fungi for A. umbelliformis field culture. PMID:21243378

  16. Local Light-Induced Modification of the Inside of Microfluidic Glass Chips.

    PubMed

    Carvalho, Rui Rijo; Pujari, Sidharam P; Lange, Stefanie C; Sen, Rickdeb; Vrouwe, Elwin Xander; Zuilhof, Han

    2016-03-15

    The ability to locally functionalize the surface of glass allows for myriad biomedical and chemical applications. This would be the case if the surface functionalization can be induced using light with wavelengths for which standard glass is almost transparent. To this aim, we present the first example of a photochemical modification of hydrogen-terminated glass (H-glass) with terminal alkenes. Both flat glass surfaces and the inside of glass microchannels were modified with a well-defined, covalently attached organic monolayer using a range of wavelengths, including sub-band-gap 302 nm ultraviolet light. A detailed characterization thereof was conducted by measurements of the static water contact angle, X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and scanning Auger microscopy (SAM). Germanium attenuated total reflection Fourier transform infrared (GATR-FTIR) indicates that the mechanism of the surface modification proceeds via an anti-Markovnikov substitution. Reacting H-glass with 10-trifluoro-acetamide-1-decene (TFAAD) followed by basic hydrolysis affords the corresponding primary amine-terminated monolayer, enabling additional functionalization of the substrate. Furthermore, we show the successful formation of a photopatterned amine layer by the specific attachment of fluorescent nanoparticles in very discrete regions. Finally, a microchannel was photochemically patterned with a functional linker allowing for surface-directed liquid flow. These results demonstrate that H-glass can be modified with a functional tailor-made organic monolayer, has highly tunable wetting properties, and displays significant potential for further applications. PMID:26976049

  17. Effect of addition of commercial rosemary extracts on potent odorants in cooked beef.

    PubMed

    Kim, Hun; Cadwallader, Keith R; Kido, Hirotsugu; Watanabe, Yuko

    2013-06-01

    Solid-phase microextraction-gas chromatography-olfactometry (SPME-GCO) and aroma extract dilution analysis (AEDA) were applied to measure the effects of the addition of two commercial rosemary extracts (RE) on the potent odorants in cooked beef extracts (BE). On the basis of the results of SPME-GCO and AEDA, the addition of RE imparted sweet and floral notes to BE as a result of the addition of esters and terpenes of RE. In addition, RE suppressed the formation of odorants derived via lipid oxidation and Maillard reactions. The most potent lipid oxidation volatiles consisted of 1-octen-3-one (mushroom-like), (E)-2,4-epoxy-(E)-2-decenal (metallic), and eight different aldehydes (fatty). The Maillard reaction volatiles, necessary for typical cooked beef flavor, included compounds with meaty [2-methyl-3-furanthiol, 2-methyl-3-(methylthio)furan, 2-methyl-3-(methyldithio)furan], roasty (2-furanmethanethiol), caramel-like [4-hydroxy-2,5-dimethyl-3(2H)-furanone], baked potato-like [3-(methylthio)propanal], and spicy [3-hydroxy-4,5-dimethyl-2(5H)-furanone] attributes. The suppressive effects of RE may be caused by the action of antioxidative substances in RE alone or in combination with the pH increase in BE induced by the matrix components of RE. PMID:23501248

  18. Semiochemical Production and Laboratory Behavior Response of the Brown Marmorated Stink Bug, Halyomorpha Halys

    PubMed Central

    Harris, Christina; Abubeker, Sitra; Yu, Mengmeng; Leskey, Tracy; Zhang, Aijun

    2015-01-01

    Background The brown marmorated stink bug (BMSB) is an exotic insect pest that was first recognized in the United States in 2001. As of today, it has been found in more than 42 states. BMSB has a very broad host plant range and damage to crops in mid-Atlantic States has reached a critical level. A reliable and accurate tool for infestation detection and population monitoring is urgently needed to provide better and more timely interventions. Pheromones produced by male BMSB have been previously identified and are currently used in BMSB infestation detection. However, the conditions affecting BMSB production of these pheromones were unknown. Methodology/Principal Findings In this study, we collected headspace volatiles from male BMSB under laboratory conditions, measured the temporal patterns of release of these pheromones, and assayed the attractiveness to conspecifics. In addition to the pheromone components, tridecane (C13) and E-2-decenal (an alarm compound) were observed in headspace collections of males, as well as in females and nymphs. Exposure of pheromone-emitting adult males to synthetic C13 greatly reduced pheromone emission. Conclusions/Significance This information should lead to a better understanding of the biology, physiology, and chemical ecology of BMSB, which will help scientists and growers develop more efficient strategies based on natural products to manage BMSB population, therefore, reducing pesticide usage and protecting the crops from BMSB damage. PMID:26528717

  19. Potential chemosignals in the anogenital gland secretion of giant pandas, Ailuropoda melanoleuca, associated with sex and individual identity.

    PubMed

    Zhang, Jian-Xu; Liu, Dingzhen; Sun, Lixing; Wei, Rongping; Zhang, Guiquan; Wu, Honglin; Zhang, Hemin; Zhao, Chenghua

    2008-03-01

    With a combination of dichloromethane extraction and analysis by gas chromatography-mass spectrometry (GC-MS), we found 39 compounds (corresponding to 38 GC peaks) in the anogenital gland secretion (AGS) of captive adult giant pandas, Ailuropoda melanoleuca, during the non-mating season. In addition to indole, squalene, and some of the straight-chain fatty acids that had been characterized previously from the AGS of giant pandas, we identified several new compounds such as decenal, two isomers of decadienal, phenylacetic acid, 5-methylhydantoin, hydroquinone, phenylpropanoic acid, and erucic acid. Quantitative comparison of the relative abundances of the 20 main GC peaks revealed that 5-methylhydantoin, indole, and erucic acid are putative female pheromones, whereas squalene and hydroquinone are putative male pheromones. In addition to the presence of a few individual-specific compounds, the relative abundances of most of the 21 constituents varied more among individuals than within individuals. This suggests that individual identity might be coded in both digital and analog form. The chemical composition of different AGS samples from the same pandas consistently displayed a minimum cluster distance, much smaller than that between samples from different individuals in a hierarchical linkage cluster (average linkage) dendrogram. Our results indicate that the AGS might contain an "odor fingerprint." Although putative sex pheromones such as squalene and erucic acid should be assessed further by bioassay, our study suggests that synthetic chemosignals might be useful in modulating the behavior and physiology of giant pandas. PMID:18293041

  20. Focus modulation of cylindrical vector beams through negative-index grating lenses

    NASA Astrophysics Data System (ADS)

    Wang, Shengming; Xu, Ji; Zhong, Yi; Ren, Rong; Lu, Yunqing; Wan, Hongdan; Wang, Jin; Ding, Jianping

    2016-08-01

    A cylindrically symmetric negative-index grating lens composed of unitary material is proposed as an effective method to modulate the focusing of cylindrical vector beams (CVBs). The grating parameters are designed to obtain an appropriate negative index, and the lens profile is tailored to realize the constructive interference. The plano-concave lens is parameterized to achieve desired focal length and the plano-cone lens is proposed to obtain large depth of focus. An optical needle is generated with radially polarized incidence, and an optical tube is achieved with incidence of azimuthal polarization. Moreover, the presented modulation methods can be applied for any arbitrary polarized CVBs. This work offers a more flexible and effective approach to design negative-index lenses for subwavelength focusing of CVBs, which has potential application value in related areas, such as optical trapping, and other nano-optics fields.

  1. Vibration Analysis of Original Shape Quartz Resonator for High Quality Factor Realization

    NASA Astrophysics Data System (ADS)

    Oigawa, Hiroshi; Sakano, Yuuya; Ji, Jing; Yamazaki, Daisuke; Ueda, Toshitsugu

    2012-06-01

    AT-cut quartz resonators are widely used as timing devices in computers, mobile information, and communication tools, etc. Recently, quartz resonators have been applied to highly sensitive devices. To improve frequency stability, AT-cut quartz resonators must have an excellent temperature characteristic and high quality (Q) factor. Energy trapping and spurious mode coupling strongly affect the performance of resonators, and both parameters are determined by the shape of the resonator. As for achieving a higher Q, the most effective technique is to process the quartz cross-sectional shape into a plano-convex or bi-convex shape. However, it is difficult to manufacture a convex shape on the surface of a quartz wafer. For this reason, we propose an equivalent plano-convex shape, which was realized by arranging fine protrusions on the surface of quartz. In addition, the optimization of the original resonator shape has been discussed.

  2. Spectra and broad-spectral laser operation of a disordered Nd:LiLa(MoO4)2 crystal

    NASA Astrophysics Data System (ADS)

    Xu, Shan; Huang, Xinyang; Li, Bingxuan; Wei, Yong; Huang, Chenghui; Zhuang, Fengjiang; Chen, Weidong; Zhai, Suya; Zhang, Ge

    2013-06-01

    The crystal characteristics of a disordered Nd:LiLa(MoO4)2 laser crystal were investigated in detail, including its structure, absorption, emission and Raman scattering spectra. Laser operation, end-pumped by an 808 nm diode laser, has been demonstrated in both a concave-plano and plane-parallel resonator cavity. A broad-spectral dual-peak laser emission at 1061 nm and 1060 nm with a full width at half maximum of 2 nm was obtained in the experiment. A maximum output power of 267 mW was obtained in the concave-plano cavity. However, in the plane-parallel cavity, laser output of 381 mW was obtained, giving a slope efficiency of 14.5%. The results lay the groundwork for Raman, mode-locked and tunable laser applications generated by a Nd:LiLa(MoO4)2 laser crystal.

  3. Spherical aberration standards and measurement system stability over time

    NASA Astrophysics Data System (ADS)

    Compertore, David; Ignatovich, Filipp; Marcus, Michael

    2015-10-01

    A Shack-Hartmann wave-front sensor system has been used to measure a set of plano-convex lenses at two different times, separated by almost 2 years. The plano-convex lenses were selected to cover a range of powers and apertures relevant to intraocular lenses, and were measured at two different orientations. The results demonstrate the high temporal stability of the measurement system, as well as of the glass standard. In addition, both times the effective focal lengths of the standards were measured using a NIST traceable nodal slide bench, and the center thicknesses were measured using low-coherence interferometer. The spherical aberration and the effective focal length results are analyzed for statistically significant changes. The results are also compared to the Zemax models of the standards.

  4. Passive Q-switching of Yb bulk lasers by a graphene saturable absorber

    NASA Astrophysics Data System (ADS)

    Loiko, P. A.; Serres, J. M.; Mateos, X.; Liu, J.; Zhang, H.; Yasukevich, A. S.; Yumashev, K. V.; Petrov, V.; Griebner, U.; Aguiló, M.; Díaz, F.

    2016-04-01

    Compact Yb:KLu(WO4)2 and Yb:LuVO4 lasers diode-pumped at 978 nm are passively Q-switched by a single-layer graphene saturable absorber. The Yb:KLu(WO4)2 laser generated 165 ns/0.49 μJ pulses at 1030 nm with 170 mW average output power and 12 % slope efficiency. With the Yb:LuVO4 laser, 152 ns/0.83 μJ pulses were achieved. The output power reached 300 mW at 1024 nm, and the slope efficiency was 10 %. Laser operation in a plano-plano cavity is achieved with both crystals with thermal lensing playing a key role in their performance. A model describing graphene Q-switched Yb lasers is developed. Our results indicate the potential of graphene for passive Q-switching of ~1 μm bulk lasers.

  5. Scattering effect and laser performance for the Nd:YAG transparent ceramics

    NASA Astrophysics Data System (ADS)

    Li, C.; Liu, W.; Gao, H.; Jiang, B.; Wang, Y.; Kou, H.; Shen, Y.; Pan, Y.; Bo, Y.; Peng, Q.; Cui, D.; Jiang, D.; Xu, Z.

    2011-09-01

    The scattering is the critical loss mechanism in transparent laser ceramic materials. We present a method to determine the scattering coefficient and absorption coefficient of laser material based on an integrating sphere technique. Here, the neodymium ceramic Nd:YAG samples with Nd3+ ions doping concentration of 1.0 at% are used. For a comparison, a Nd:YAG single crystal with identical concentration is also employed. The measured scattering coefficient and absorption coefficient at 1064 nm for high quality ceramic Nd:YAG were 0.004 cm-1 and 0.001 cm-1, which were very close to that of single crystal. The optical uniformity and wave-front distortion properties were also investigated by means of a Hartmann wavefront analyzer. The following laser performance tests demonstrate a maximum output power of 425 W in a short plano-plano configuration for the high quality Nd:YAG ceramic, which was nearly same with that of single crystal.

  6. High Speed Surface Micro-Polishing for Spurious Reduction of Small Quartz Crystal Blanks

    NASA Astrophysics Data System (ADS)

    Hatsuzawa, Takeshi; Hamano, Hisashi; Saito, Masashi; Yanagida, Yasuko

    Surface polishing is required for small crystal blanks to eliminate frequency spurious generated by the infinite rectangular shape. From the productivity viewpoint, bi-convex or plano-cylindrical surface are generally used to realize the energy trapping at the central part of the blanks. So far barrel polishing is the common fabrication technology to obtain bi-convex surface, however, the surface is finished insufficiently and fabrication process takes longer time as the blank size becomes small. To solve this difficulty, two types of new surface micro-polishing mechanisms with fixed abrasive and arrayed blank arrangement are experimentally examined to obtain plano-cylindrical surface. The fastest finishing time of 10 s for a blank is achieved together with the spurious elimination.

  7. Sistema Planeta-Satélite. Simulación orbital y potenciales gravitatorios

    NASA Astrophysics Data System (ADS)

    Medina, C.; Carrillo, M.

    Se presenta un programa (desarrollado en Quick Basic 4.5) que simula, en tres dimensiones, el movimiento orbital de un satélite (o luna) alrededor de un planeta, al tiempo que calcula y grafica, en un plano, el potencial gravitatorio del sistema en función de la distancia al planeta. Para la simulación orbital, se emplea la matriz de transformación entre el sistema del planeta y el plano orbital. Para el cálculo y graficación del potencial se aplica un desarrollo en serie hasta el segundo orden, que da cuenta del efecto de achatamiento de los polos, en caso de que éste exista. Las longitudes de los ejes del planeta, la masa de éste y del satélite, sus tamaños aparentes, y los parámetros orbitales son introducidos por el usuario.

  8. Highly efficient TEM00 mode LD-pumping 1063nm Nd:GdVO4 laser with short cavity

    NASA Astrophysics Data System (ADS)

    Liu, Xiaojuan; Fu, Shenggui; Ge, Xiaolu; Yuan, Changkun

    2011-11-01

    A highly efficient TEM00 mode 1063 nm Nd:GdVO4 laser is accomplished with a simple plano-plano resonator. The laser threshold pump power is 856 mW. The maximum laser power of 2.05W is achieved when the pump power is 3.76 W, corresponding to a slope-efficiency of 70% to absorbed pump power. The quality of the output beam is analyzed with a laser beam quality analyzer. The perfect laser beam quality is partially attributed to the short cavity length of 11 mm and the precise temperature control to the Nd:GdVO4 crystal. The output laser central wavelength is 1063.1 nm with a laser linewidth of 0.06 nm.

  9. Investigation of the neutral-solution etch process for refractive SOE antireflective surfaces

    SciTech Connect

    Maish, A.B.

    1991-01-01

    Antireflection of optically clear glass used in photovoltaic concentrator refractive secondary optical elements (SOE's) was investigated using the neutral-solution etch process developed by Schott Glass. Test coupons and SOE's made from barium zinc glass, which does not solarize under ultraviolet exposure, were successfully etched at the center point process variable conditions of 87{degrees}C and 24 hours. Reflectance of the plano-plano dropped from 7.7% to 0.8%, with a corresponding increase in transmission from 91.7% to 98.5%. The etching process uses non-hydrofluoric, relatively non-toxic chemicals in a low-cost process well suited for use by photovoltaic system manufacturers during production. 10 refs., 4 figs., 1 tab.

  10. Ion-Etching As A Means Of Blazing And Optimizing Holographic Diffraction Gratings

    NASA Astrophysics Data System (ADS)

    Lerner, J. M.; Flamand, J.; Thevenon, A.

    1983-07-01

    Holographic diffraction gratings, when used in a spectroscopic application, produce excellent image quality and stray-light rejection, but sometimes lack optimum efficiency. Ionetching through a sinusoidal photoresist groove into a glass substrate can produce triangular profiles comparable with the groove shape produced by classical diamond burnishing. This can be accomplished in both plano, spherical and aspheric substrates to produce gratings comparable in efficiency to classically ruled gratings.

  11. Interferometric study on Gouy phase anomaly of microlens array

    NASA Astrophysics Data System (ADS)

    Kim, Myun-Sik; Scharf, Toralf; Noell, Wilfried; Herzig, Hans Peter; Voelkel, Reinhard

    2015-03-01

    We investigate the Gouy phase anomaly of light in the focus of refractive plano-convex microlens arrays by using longitudinal-differential (LD) interferometry and a finite-difference time-domain (FDTD) simulation. We put emphasis on determining the amount of the Gouy phase shift for the line focus of the cylindrical lens and the point focus of the spherical lens. We discuss additional phase structures caused by diffraction, which lead to the discrepancy from the conventional Gouy phase shift.

  12. Photonic spin filter with dielectric metasurfaces.

    PubMed

    Ke, Yougang; Liu, Yachao; Zhou, Junxiao; Liu, Yuanyuan; Luo, Hailu; Wen, Shuangchun

    2015-12-28

    We propose a photonic spin filter whose structure is similar to that of conventional spatial filter, but the two plano-convex lenses are replaced by Pancharatnam-Berry phase ones. The dielectric metasurface with high transmission and conversion efficiency is designed to work as Pancharatnam-Berry phase lens. The photonic spin filter can sort desired spin photons from the input beam with mixed spin states, and thereby facilitate possible applications in spin-based photonics. PMID:26831976

  13. Innovative optics for shaping and focusing industrial CO2 lasers

    NASA Astrophysics Data System (ADS)

    Danielewicz, Edward J.; Sherman, Glenn H.

    1989-03-01

    Applications of diamond-turned axicons for high power CO2 lasers are reviewed. The use of transmissive and reflective axicons in laser applications and the use of faceted optics for shaping and directing laser light are discussed. Diamond-turned ZnSe lenses are compared with conventional plano-convex and meniscus lenses. Results are presented from cutting and welding plastics and metals, noting the advantages of diamond-turned focusing elements.

  14. [In Process Citation].

    PubMed

    López-Fuenzalida, Antonio; Rodríguez Canales, Carolina; Reyes Ponce, Álvaro; Contreras Molina, Ángela; Fernández Quezada, Javiera; Aguirre Polanco, Carolina

    2016-01-01

    Introducción: dado el incremento del sobrepeso y obesidad infantil, es relevante estudiar no solo las consecuencias metabólicas, sino también aquellas de índole musculoesqueléticas que pueden afectar la funcionalidad motriz, como es el pie plano, en esta población. Objetivo: identificar la asociación entre el estado nutricional y la prevalencia de pie plano en niños y niñas chilenos de 6 a 10 años. Métodos: el z-score del índice de masa corporal (IMC) y el registro y análisis de las huellas plantares según la metodología de Hernández-Corvo fue llevado a cabo en 388 escolares (52,3% niñas). Un test de diferencia para dos proporciones fue utilizado para evaluar las diferencias entre los grupos. Se considera una significancia estadística con p ≤ 0,05. Resultados: la prevalencia del exceso de peso fue de más del 40%. Esta prevalencia fue más alta en las niñas (47,8%) que en los niños (42,7%). La prevalencia de pie plano en todos los niños fue del 17%, presentando valores más elevados el pie derecho (18,3%) que el izquierdo (15,7%). Hay un incremento significativo de la prevalencia de pie plano en los niños obesos en relación con los niños con sobrepeso y normopeso. Conclusión: el estado nutricional está asociado con incrementos en la prevalencia de pie plano en niños. En la población infantil de 6 a 10 años de edad, la obesidad está asociada con la alteración morfológica del pie. PMID:27238781

  15. Metaphoric Reference: An Eye Movement Analysis of Spanish–English and English–Spanish Bilingual Readers

    PubMed Central

    Heredia, Roberto R.; Cieślicka, Anna B.

    2016-01-01

    This study examines the processing of metaphoric reference by bilingual speakers. English dominant, Spanish dominant, and balanced bilinguals read passages in English biasing either a figurative (e.g., describing a weak and soft fighter that always lost and everyone hated) or a literal (e.g., describing a donut and bakery shop that made delicious pastries) meaning of a critical metaphoric referential description (e.g., “creampuff”). We recorded the eye movements (first fixation, gaze duration, go-past duration, and total reading time) for the critical region, which was a metaphoric referential description in each passage. The results revealed that literal vs. figurative meaning activation was modulated by language dominance, where Spanish dominant bilinguals were more likely to access the literal meaning, and English dominant and balanced bilinguals had access to both the literal and figurative meanings of the metaphoric referential description. Overall, there was a general tendency for the literal interpretation to be more active, as revealed by shorter reading times for the metaphoric reference used literally, in comparison to when it was used figuratively. Results are interpreted in terms of the Graded Salience Hypothesis (Giora, 2002, 2003) and the Literal Salience Model (Cieślicka, 2006, 2015). PMID:27065911

  16. Metaphoric Reference: An Eye Movement Analysis of Spanish-English and English-Spanish Bilingual Readers.

    PubMed

    Heredia, Roberto R; Cieślicka, Anna B

    2016-01-01

    This study examines the processing of metaphoric reference by bilingual speakers. English dominant, Spanish dominant, and balanced bilinguals read passages in English biasing either a figurative (e.g., describing a weak and soft fighter that always lost and everyone hated) or a literal (e.g., describing a donut and bakery shop that made delicious pastries) meaning of a critical metaphoric referential description (e.g., "creampuff"). We recorded the eye movements (first fixation, gaze duration, go-past duration, and total reading time) for the critical region, which was a metaphoric referential description in each passage. The results revealed that literal vs. figurative meaning activation was modulated by language dominance, where Spanish dominant bilinguals were more likely to access the literal meaning, and English dominant and balanced bilinguals had access to both the literal and figurative meanings of the metaphoric referential description. Overall, there was a general tendency for the literal interpretation to be more active, as revealed by shorter reading times for the metaphoric reference used literally, in comparison to when it was used figuratively. Results are interpreted in terms of the Graded Salience Hypothesis (Giora, 2002, 2003) and the Literal Salience Model (Cieślicka, 2006, 2015). PMID:27065911

  17. 12th Annual Conference on Vaccine Research.

    PubMed

    O'Brien, Jennifer

    2009-09-01

    The 12th Annual Conference on Vaccine Research, hosted by the National Foundation for Infectious Disease, attracted approximately 450 leaders in the fields of epidemiology, health economics, immunology and vaccinology, making it the largest scientific meeting devoted exclusively to vaccine research and technology. The conference highlighted recent issues in vaccine safety, including the history and design of a vaccine for rotavirus. Other topics included discussions of the synergies between veterinary and human vaccine development, updates on the development of vaccines for tuberculosis and malaria, and a comprehensive overview of immunization initiatives and goals for extending coverage of new and underused vaccines. Keynote remarks were provided by David Salisbury (Department of Health, London, UK) who outlined the aims and objectives of the Global Immunization Vision and Strategy (GIVS), an agenda created by the WHO and UNICEF. Salisbury highlighted the four primary aims of GIVS: immunize more people against more diseases, introduce a range of newly available vaccines and technologies, integrate other critical health interventions with immunization, and manage vaccination programs within the context of global interdependence. The GIVS initiative spans the time period of 2006-2015. PMID:19722886

  18. Morphological characteristics of Mesocestoides canislagopodis (Krabbe 1865) tetrathyridia found in rock ptarmigan (Lagopus muta) in Iceland.

    PubMed

    Skirnisson, Karl; Sigurðardóttir, Ólöf G; Nielsen, Ólafur K

    2016-08-01

    Necropsies of 1010 rock ptarmigans (Lagopus muta) sampled in autumn 2006-2015 in northeast Iceland revealed Mesocestoides canislagopodis tetrathyridia infections in six birds (0.6 %), two juvenile birds (3 month old), and four adult birds (15 months or older). Four birds had tetrathyridia in the body cavity, one bird in the liver, and one bird both in the body cavity and the liver. There were more tetrathyridia in the body cavity of the two juveniles (c. 50 in each) than in three adults (10-40), possibly indicating a host-age-related tetrathyridia mortality. Approximately, half of tetrathyridia in the body cavity were free or loosely attached to the serosa, the other half were encapsulated in a thin, loose connective tissue stroma, frequently attached to the lungs and the liver. Tetrathyridia in the liver parenchyma incited variably intense inflammation. Tetrathyridia from the juvenile hosts were whitish, heart-shaped, and flattened, with unsegmented bodies with a slightly pointed posterior end. In the adult hosts, tetrathyridia were sometimes almost rectangular-shaped, slightly wider compared to those in the juveniles, but more than twice as long as the younger-aged tetrathyridia. Tetrathyridia infections are most likely acquired during the brief insectivorous feeding phase of ptarmigan chicks, and the tetrathyridia persist throughout the lifespan of the birds. PMID:27117162

  19. Technology development for long-lived Venus landers.

    NASA Astrophysics Data System (ADS)

    Ekonomov, 1.; Korablev, O.; Zasova, L.

    2007-08-01

    Simultaneously with many successful lander missions on Venus in 1972-1985 Soviet Union began develop long-lived lander on surface of Venus. The basic problem were extreme conditions on a surface: P=10MPa, T=500 C . Then operations have been stopped and have renewed in 2006 already in new Russia. Mission "VENERA (VENUS) - D" is included into the Federal space program of Russia on 2006 - 2015 with launch in 2016. To this date Russia alone can't create a reliable electronics for 500 C, but we have got examples GaN electronics for 350 C. Cooling technology with boiling water is offered for interior devices of lander at pressure 10 MPa and temperature 310 C. As the power source of an electronics we use high-temperature galvanic cells on the base of Li4Si [LiCl, KCl, LiF] FeS2 which are released in Russia as reserve power sources. They are capable to work directly on a surface of Venus without any thermal protection. At lander two kinds of vacuum technology can be used: 1) in multilayer (MLI ) thermal blanket for lander, 2) in electro-vacuum devices, for example transmitter . For creation and maintenance of vacuum at temperature 400-500 C: chemical gas absorbers ( getter materials ) are used, they actively absorb both carbon dioxide and nitrogen .

  20. Reprint of "Acquisition of choice in concurrent chains: Assessing the cumulative decision model".

    PubMed

    Grace, Randolph C

    2016-06-01

    Concurrent chains is widely used to study pigeons' choice between terminal links that can vary in delay, magnitude, or probability of reinforcement. We review research on the acquisition of choice in this procedure. Acquisition has been studied with a variety of research designs, and some studies have incorporated no-food trials to allow for timing and choice to be observed concurrently. Results show that: Choice can be acquired rapidly within sessions when terminal links change unpredictably; under steady-state conditions, acquisition depends on both initial- and terminal-link schedules; and initial-link responding is mediated by learning about the terminal-link stimulus-reinforcer relations. The cumulative decision model (CDM) proposed by Christensen and Grace (2010) and Grace and McLean (2006, 2015) provides a good description of within-session acquisition, and correctly predicts the effects of initial and terminal-link schedules in steady-state designs (Grace, 2002a). Questions for future research include how abrupt shifts in preference within individual sessions and temporal control of terminal-link responding can be modeled. PMID:27150444

  1. Acquisition of choice in concurrent chains: Assessing the cumulative decision model.

    PubMed

    Grace, Randolph C

    2016-05-01

    Concurrent chains is widely used to study pigeons' choice between terminal links that can vary in delay, magnitude, or probability of reinforcement. We review research on the acquisition of choice in this procedure. Acquisition has been studied with a variety of research designs, and some studies have incorporated no-food trials to allow for timing and choice to be observed concurrently. Results show that: Choice can be acquired rapidly within sessions when terminal links change unpredictably; under steady-state conditions, acquisition depends on both initial- and terminal-link schedules; and initial-link responding is mediated by learning about the terminal-link stimulus-reinforcer relations. The cumulative decision model (CDM) proposed by Christensen and Grace (2010) and Grace and McLean (2006, 2015) provides a good description of within-session acquisition, and correctly predicts the effects of initial and terminal-link schedules in steady-state designs (Grace, 2002a). Questions for future research include how abrupt shifts in preference within individual sessions and temporal control of terminal-link responding can be modeled. PMID:27005579

  2. DNA and dispersal models highlight constrained connectivity in a migratory marine megavertebrate

    USGS Publications Warehouse

    Naro-Maciel, Eugenia; Hart, Kristen M.; Cruciata, Rossana; Putman, Nathan F.

    2016-01-01

    Population structure and spatial distribution are fundamentally important fields within ecology, evolution, and conservation biology. To investigate pan-Atlantic connectivity of globally endangered green turtles (Chelonia mydas) from two National Parks in Florida, USA, we applied a multidisciplinary approach comparing genetic analysis and ocean circulation modeling. The Everglades (EP) is a juvenile feeding ground, whereas the Dry Tortugas (DT) is used for courtship, breeding, and feeding by adults and juveniles. We sequenced two mitochondrial segments from 138 turtles sampled there from 2006-2015, and simulated oceanic transport to estimate their origins. Genetic and ocean connectivity data revealed northwestern Atlantic rookeries as the major natal sources, while southern and eastern Atlantic contributions were negligible. However, specific rookery estimates differed between genetic and ocean transport models. The combined analyses suggest that post-hatchling drift via ocean currents poorly explains the distribution of neritic juveniles and adults, but juvenile natal homing and population history likely play important roles. DT and EP were genetically similar to feeding grounds along the southern US coast, but highly differentiated from most other Atlantic groups. Despite expanded mitogenomic analysis and correspondingly increased ability to detect genetic variation, no significant differentiation between DT and EP, or among years, sexes or stages was observed. This first genetic analysis of a North Atlantic green turtle courtship area provides rare data supporting local movements and male philopatry. The study highlights the applications of multidisciplinary approaches for ecological research and conservation.

  3. Temporal variations and trends in loads of commonly used pharmaceuticals to large wastewater treatment plants in Sweden, a case study (Ryaverket).

    PubMed

    Paxéus, N; Bester, K; El-taliawy, Haitham

    2016-01-01

    Loads of individual commonly used analgesics (ibuprofen, diclofenac), antibiotics (sulfamethoxazole, trimethoprim), β-blockers (atenolol, metoprolol, sotalol, propranolol) and neuroleptics (carbamazepine, citalopram) to a large-scale operating wastewater treatment plant (WWTP) in Sweden (Ryaverket) were studied by monitoring concentrations and flows during a 9-year period (2006-2015). Variations in loads due to sampling and possible errors in chemical analyses were estimated to be below 40%. The variations in loads were analyzed and discussed in terms of the design of collecting wastewater system as an integrated part of the water treatment at the WWTP as well as the prescription and use of individual pharmaceuticals. Trend analysis in daily loads of individual pharmaceuticals indicated an increase for diclofenac, no significant changes for ibuprofen and metoprolol and a decrease for the other pharmaceuticals. The latter was ascribed to a decrease in their prescription and use. The increase in loads of diclofenac was ascribed to its growing topical use not requiring prescription. In view of future regulations by the EU, growing loads of diclofenac to WWTPs and its low removal rates in WWTPs may require an upgrade of WWTPs to achieve quality standards for diclofenac in receiving waters. PMID:27332852

  4. Urinary cadmium concentration and risk of breast cancer: a systematic review and dose-response meta-analysis.

    PubMed

    Larsson, Susanna C; Orsini, Nicola; Wolk, Alicja

    2015-09-01

    Cadmium is a toxic and persistent heavy metal with estrogenic activities. We conducted a systematic review and meta-analysis of cohort, case-control, and cross-sectional studies of the association between urinary cadmium concentration, a biomarker of cadmium exposure, and breast cancer risk. Studies were identified by searching PubMed and Embase (to March 15, 2015) and by reviewing the reference lists of pertinent articles. Study-specific risk estimates were combined by using a random-effects model. We identified 2 cohort studies (with 67 breast cancer deaths) and 5 case-control studies and 1 cross-sectional study (with 1,416 cases and 5,083 controls) on urinary cadmium concentration in relation to breast cancer risk. The studies were published during the past 10 years (2006-2015). There was no consistent association between urinary cadmium and breast cancer mortality in the cohort studies. In case-control and cross-sectional studies, the pooled odds ratios were 2.24 (95% confidence interval: 1.50, 3.34; I(2) = 63.4%) for the highest versus lowest category of cadmium concentration and 1.66 (95% confidence interval: 1.23, 2.25) for each 0.5-µg/g creatinine increase of cadmium concentration. This meta-analysis suggests that a high cadmium exposure may be a risk factor for breast cancer, but large prospective studies are needed to confirm this finding. PMID:26254432

  5. NOx and NOy in the Tropical Marine Boundary Layer

    NASA Astrophysics Data System (ADS)

    Reed, Chris; Evans, Mathew J.; Lee, James D.; Carpenter, Lucy J.; Read, Katie A.; Mendes, Luis N.

    2016-04-01

    Nitrogen oxides (NOx=NO+NO2) and their reservoir species (NOy) play a central role in determining the chemistry of the troposphere. Although their concentrations are low (1-100 ppt) in regions such as the remote marine boundary layer, they have a profound impact on ozone production and the oxidizing capacity. There are very few observations of NOx and NOy in remote oceanic regions due to the technical challenges of measuring such low concentrations, and thus our understanding of this background chemistry is incomplete. Here we present long term measurements of NOx (2006-2015) and more recent measurements of speciated NOy (total peroxyacetyl nitrates, PANs; alkyl nitrates, ANs; nitric acid; and aerosol analogues) made at the Cape Verde Atmospheric Observatory (CVAO; 16° 51' N, 24° 52' W) located in the tropical Atlantic Ocean. We identify potential interferences in the NO2 and NOy measurements and methods to eliminate them. Diurnal and seasonal cycles are interpreted using a box model. We find a complex chemistry with interactions between organic and inorganic chemistry, between the aerosol and gas phase, and between the very local and large scales.

  6. The contribution of ozone to future stratospheric temperature trends

    NASA Astrophysics Data System (ADS)

    Maycock, A. C.

    2016-05-01

    The projected recovery of ozone from the effects of ozone depleting substances this century will modulate the stratospheric cooling due to CO2, thereby affecting the detection and attribution of stratospheric temperature trends. Here the impact of future ozone changes on stratospheric temperatures is quantified for three representative concentration pathways (RCPs) using simulations from the Fifth Coupled Model Intercomparison Project (CMIP5). For models with interactive chemistry, ozone trends offset ~50% of the global annual mean upper stratospheric cooling due to CO2 for RCP4.5 and 20% for RCP8.5 between 2006-2015 and 2090-2099. For RCP2.6, ozone trends cause a net warming of the upper and lower stratosphere. The misspecification of ozone trends for RCP2.6/RCP4.5 in models that used the International Global Atmospheric Chemistry (IGAC)/Stratosphere-troposphere Processes and their Role in Climate (SPARC) Ozone Database causes anomalous warming (cooling) of the upper (lower) stratosphere compared to chemistry-climate models. The dependence of ozone chemistry on greenhouse gas concentrations should therefore be better represented in CMIP6.

  7. Future Projections of Trans-Arctic Shipping Potential and Variability

    NASA Astrophysics Data System (ADS)

    Stephenson, S. R.; Smith, L. C.

    2014-12-01

    As the Arctic Ocean transitions towards a seasonally ice-free state, efforts to predict new connections between the Arctic and the global economy are underway. In particular, record lows in September sea ice extent from 2007-2013 have recast Arctic shipping routes as emerging international seaways for export of resources and as potential alternative pathways for global trade. While ensemble-averaged output from sea ice models suggest significant increases in vessel accessibility in September by midcentury (Smith & Stephenson, 2013), the seasonal length and variability of trans-Arctic shipping is not well understood. In addition, differences in ice extent due to inter-model variability reveal significant uncertainties in the magnitude and location of future vessel access. Here we present several scenarios of 21st-century trans-Arctic shipping as driven by sea ice output from CMIP5 models. Optimal vessel transits from North America and Europe to the Bering Strait are estimated for two periods representing present-day (2006-2015) and midcentury (2040-2059) conditions under two forcing scenarios (RCP 4.5/8.5), assuming Polar Class 6 (PC6) and open-water vessels (OW) with medium and no ice-breaking capability, respectively. Results illustrate a range of potential futures for shipping in the Arctic owing to differences in model choice, vessel capability, and climate forcing. Inter-model differences reveal the importance of model choice in devising projections for strategic planning by governments, environmental agencies, and the global maritime industry.

  8. Potato wound-healing tissues: A rich source of natural antioxidant molecules with potential for food preservation.

    PubMed

    Dastmalchi, Keyvan; Wang, Isabel; Stark, Ruth E

    2016-11-01

    The need for safe, effective preservatives is a prominent issue in the food and drug industries, reflecting demand for natural alternatives to synthetic chemicals viewed as harmful to consumers and the environment. Thus, this study determined the identities and scavenging capacities of antioxidant metabolites produced as a response to potato tuber wounding, using activity-guided fractionation of polar extracts from a Yukon Gold cultivar that had previously exhibited exceptionally high radical-scavenging activity. Activity-guided fractionation using the ABTS(+) radical scavenging assay and LC-MS with TOF-MS for compositional analysis of the most potent antioxidant fractions yielded identification of nine constituents: coumaroylputrescine; feruloylquinic acid; isoferuloylputrescine; ferulic acid; 22,25-dimethoxy-3-[[2,3,4-tri-O-methyl-6-O-(2,3,4,6-tetra-O-methyl-β-d-glucopyranosyl)-β-d-glucopyranosyl]oxy]-(3β)-lanost-9(11)-en-24-one; 4-(2Z)-2-decen-1-yl-5-[1-(4-hydroxyphenyl)decyl]-1,2-benzenediol; 8-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-5-hydroxy-2,8-dimethyl-6-(3-methyl-2-buten-1-yl)-2H-1-benzopyran-4,7(3H,8H)-dione; 3-[(2-O-β-d-glucopyranosyl-β-d-glucopyranosyl)oxy]-20-[(6-O-β-d-xylopyranosyl-β-d-glucopyranosyl)oxy]-dammar-24-en-19-al; (3β)-28-oxo-28-(phenylmethoxy)oleanan-3-yl 2-O-β-d-galactopyranosyl-3-O-(phenylmethyl)-, butyl ester β-d-glucopyranosiduronic acid. A positive correlation was observed between the scavenging activities and the polarities of the active fractions. The antioxidant capacities of the fractions were also characterised by monitoring the activity throughout a 45-minute assay period. PMID:27211673

  9. Behavioral responses of the leafhopper, Cicadulina storeyi China, a major vector of maize streak virus, to volatile cues from intact and leafhopper-damaged maize.

    PubMed

    Oluwafemi, Sunday; Bruce, Toby J A; Pickett, John A; Ton, Jurriaan; Birkett, Michael A

    2011-01-01

    The chemical ecology of the leafhopper, Cicadulina storeyi China (Homoptera: Cicadellidae), an important vector of Maize Streak Virus (MSV), was studied with a view to developing novel leafhopper control strategies in sub-Saharan Africa. Choice tests using a Y-tube olfactometer revealed that odors from uninfested maize seedlings (Zea mays cv. Delprim) were significantly more attractive to C. storeyi than odors from C. storeyi-infested seedlings. Headspace samples of volatile organic compounds (VOCs) collected from 10 to 12 day-old uninfested seedlings were more attractive than those collected from infested seedlings. While VOCs collected from uninfested maize seedlings were attractive, VOCs collected from C. storeyi-infested seedlings were significantly repellent. Analysis of the collected VOCs by gas chromatography (GC) and coupled GC-mass spectrometry (GC-MS) led to the identification of myrcene, linalool, (E)-2-decen-1-ol, and decanal from uninfested seedlings, and (Z)-3-hexenyl acetate, (E)-4,8-dimethyl-1,3,7-nonatriene (DMNT), methyl salicylate, benzyl acetate, indole, geranyl acetate, (E)-caryophyllene, α-bergamotene, (E)-β-farnesene, β-sesquiphellandrene, and (E,E)-4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) from infested seedlings. Of these, methyl salicylate, (E)-caryophyllene, (E)-β-farnesene, and TMTT were identified previously as volatile semiochemicals involved in plant defense against other sucking insect pests. When tested individually for behavioral activity, all compounds were repellent for C. storeyi. Moreover, when these induced VOCs were added to the blend of VOCs from uninfested maize seedlings, a shift from attraction to repellency was observed. Addition of methyl salicylate, (E)-β-farnesene, or TMTT resulted in a choice for the solvent control (i.e., repulsion), whereas addition of (E)-caryophyllene resulted in no reduction in host VOC attractiveness. These results show that VOCs induced in maize have the potential to be exploited

  10. Breath Analysis in Pulmonary Arterial Hypertension

    PubMed Central

    Cikach, Frank S.; Tonelli, Adriano R.; Barnes, Jarrod; Paschke, Kelly; Newman, Jennie; Grove, David; Dababneh, Luma; Wang, Sihe

    2014-01-01

    Background: Pulmonary arterial hypertension (PAH) is a progressive and devastating condition characterized by vascular cell proliferation and is associated with several metabolic derangements. We hypothesized that metabolic derangements in PAH can be detected by measuring metabolic by-products in exhaled breath. Methods: We collected breath and blood samples from patients with PAH at the time of right-sided heart catheterization (n = 31) and from healthy control subjects (n = 34). Breath was analyzed by selected ion flow tube-mass spectrometry in predetermined training and validation cohorts. Results: Patients with PAH were 51.5 ± 14 years old, and 27 were women (85%). Control subjects were 38 ± 13 years old, and 22 were women (65%). Discriminant analysis in the training set identified three ion peaks (H3O+29+, NO+56+, and O2+98+) and the variable age that correctly classified 88.9% of the individuals. In an independent validation cohort, 82.8% of the individuals were classified correctly. The concentrations of the volatile organic compounds 2-propanol, acetaldehyde, ammonia, ethanol, pentane, 1-decene, 1-octene, and 2-nonene were different in patients with PAH compared with control subjects. Exhaled ammonia was higher in patients with PAH (median [interquartile range]: 94.7 parts per billion (ppb) [70-129 ppb] vs 60.9 ppb [46-77 ppb], P < .001) and was associated with right atrial pressure (ρ = 0.57, P < .001), mean pulmonary artery pressure (ρ = 0.43, P = .015), cardiac index by thermodilution (ρ = −0.39, P = .03), pulmonary vascular resistance (ρ = 0.40, P = .04), mixed venous oxygen (ρ = −0.59, P < .001), and right ventricular dilation (ρ = 0.42, P = .03). Conclusions: Breathprint is different between patients with PAH and healthy control subjects. Several specific compounds, including ammonia, were elevated in the breath of patients with PAH. Exhaled ammonia levels correlated with severity of disease. PMID:24091389

  11. Use of an in vitro digestion model to study the bioaccessibility of 4-hydroxy-2-nonenal and related aldehydes present in oxidized oils rich in omega-6 acyl groups.

    PubMed

    Goicoechea, Encarnación; Van Twillert, Klaas; Duits, Menno; Brandon, Esther D F A; Kootstra, Peter R; Blokland, Marco H; Guillén, María D

    2008-09-24

    Mixtures of either sunflower oil or thermodegraded sunflower oil and a standard meal were submitted to an in vitro digestion model. The same experiment was carried out with fluid deep-frying fat and thermodegraded fluid deep-frying fat. The thermodegradation of the oil and fat was provoked by submitting them to 190 degrees C with aeration in a convection oven, and the presence in the headspace of the thermodegraded oil and fat of oxygenated alpha,beta-unsaturated aldehydes (OalphabetaUAs), such as 4-hydroxy-2-nonenal (HNE), 4-oxo-2-nonenal (ONE), and 4,5-epoxy-2-decenal (EDE), was monitored by solid phase microextraction (SPME) followed by gas chromatography-mass spectrometry (GC-MS). The digestion products were separated by centrifugation in a lipidic phase, an aqueous phase, and a pellet phase. The headspace of these three phases was also studied by SPME/GC-MS to check if the toxic and very reactive OalphabetaUAs above-mentioned remained unaltered after the in vitro digestion process or if they had reacted with the various compounds present in the digestion products, so disappearing from the samples. With the same aim the extract in ethyl acetate of the aqueous and pellet phases, and of the lipidic phase after dilution, were studied by GC-MS. All results obtained showed that a certain proportion of the toxic OalphabetaUAs remains unaltered after digestion, dispersed in the three phases above-mentioned, and thus are bioaccessible in the gastrointestinal tract and so could reach the systemic circulation. Compounds that may originate in Maillard type reactions (2-pentylpyridine) are found among digestion products, proving that these reactions are possible in this process if adequate substrates are present. In addition, it has been shown that toxic metabolites from the synthetic antioxidant BHT, present in fat before digestion, remain unaltered after this process and could reach the systemic circulation. PMID:18729379

  12. Asplenioideae Species as a Reservoir of Volatile Organic Compounds with Potential Therapeutic Properties.

    PubMed

    Froissard, Didier; Rapior, Sylvie; Bessière, Jean-Marie; Buatois, Bruno; Fruchier, Alain; Sol, Vincent; Fons, Françoise

    2015-06-01

    Twelve French Asplenioideae ferns (genera Asplenium and subgenera Ceterach and Phyllitis) were investigated for the first time for volatile organic compounds (VOC) using GC-MS. Sixty-two VOC biosynthesized from the lipidic, shikimic, terpenic and carotenoid pathways were identified. Several VOC profiles can be highlighted from Asplenium jahandiezii and A. xalternifolium with exclusively lipidic derivatives to A. onopteris with an equal ratio of lipidic/shikimic compounds. Very few terpenes as caryophyllene derivatives were identified, but only in A. obovatum subsp. bilotii. The main odorous lipidic derivatives were (E)-2-decenal (waxy and fatty odor), nonanal (aldehydic and waxy odor with a fresh green nuance), (E)-2-heptenal (green odor with a fatty note) and 1-octen-3-ol (mushroom-like odor), reported for all species. A few VOC are present in several species in high content, i.e., 9-oxononanoic acid used as a precursor for biopolymers (19% in A. jahandiezii), 4-hydroxyacetophenone with a sweet and heavy floral odor (17.1% in A. onopteris), and 4-hydroxybenzoic acid used as a precursor in the synthesis of parabens (11.3% in A. foreziense). Most of the identified compounds have pharmacological activities, i.e., octanoic acid as antimicrobial, in particular against Salmonellas, with fatty and waxy odor (41.1% in A. petrarchae), tetradecanoic acid with trypanocidal activity (13.3% in A. obovatum subsp. bilotii), 4-hydroxybenzoic acid (8.7% in A. onopteris) with antimicrobial and anti-aging effects, 3,4-dihydroxybenzaldehyde as an inhibitor of growth of human cancer cells (6.7% in Ceterach officinarum), and phenylacetic acid with antifungal and antibacterial activities (5.8% in A. onopteris). Propionylfilicinic acid was identified in the twelve species. The broad spectrum of odorous and bioactive VOC identified from the Asplenium, Ceterach and Phyllitis species are indeed of great interest to the cosmetic and food industries. PMID:26197556

  13. Influence of storage on volatile profiles in roasted almonds (Prunus dulcis).

    PubMed

    Lee, Jihyun; Xiao, Lu; Zhang, Gong; Ebeler, Susan E; Mitchell, Alyson E

    2014-11-19

    Hexanal, peroxide value, and lipid hydroperoxides are common indicators of lipid oxidation in food products. However, these markers are not always reliable as levels are dynamic and often can be detected only after significant oxidation has occurred. Changes in the volatile composition of light- and dark-roast almonds were evaluated during storage over 24 weeks at 25 or 35 °C using headspace solid phase microextraction (HS-SPME) gas chromatography-mass spectrometry (GC-MS). Several volatile changes were identified in association with early oxidation events in roasted almonds. Hexenal decreased significantly during the first 6 weeks of storage and did not increase above initial levels until 20-24 weeks of storage depending upon the degree of roast. In contrast, levels of 1-heptanol and 1-octanol increased at 16-20 weeks, depending upon the degree of roast, and no initial losses were observed. Seventeen new compounds, absent in raw and freshly roasted almonds but detectable after 6 weeks of storage, were identified. Of these, 2-octanone, 2-nonanone, 3-octen-2-one, 2-decanone, (E)-2-decenal, 2,4-nonadienal, pentyl oxirane, and especially acetic acid increased significantly (that is, >10 ng/g). The degree of roasting did not correlate with the levels of these compounds. Significant decreases in roasting-related aroma volatiles such as 2-methylbutanal, 3-methylbutanal, furfural, 2-phenylacetaldehyde, 2,3-butanedione, 2-methylpyrazine, and 1-methylthio-2-propanol were observed by 4 weeks of storage independent of the degree of roast or storage conditions. PMID:25347382

  14. Effect of the inclusion of chestnut in the finishing diet on volatile compounds during the manufacture of dry-cured "Lacón" from Celta pig breed.

    PubMed

    Lorenzo, José M; Franco, Daniel; Carballo, Javier

    2014-01-01

    The effect of the finishing diet on the volatile compounds throughout the manufacture of dry-cured "lacón" (a Spanish traditional meat product), from the Celta pig breed was studied. Thirty-six pigs were separated into three groups according to the type of feeding during the finish-fattening period of three months (concentrate, mixed diet and chestnut). From the pigs of each diet, four batches of dry-cured "lacón" were manufactured. From each batch, samples of fresh meat, meat after salting, after post-salting, and after 14, 28, 56 and 84 days of drying-ripening were taken. Volatiles were extracted by a purge-and-trap method and analyzed by gas chromatographic/mass spectrometry (GC/MS). Seventy-six volatile compounds were identified and quantified from dry-cured "lacón" samples in pigs finished with chestnut, eighty-two for concentrate fed pigs and eighty in pigs fed with the mixed diet. The number of identified volatile compounds increased during the manufacturing process; at 84 days of drying-ripening, in the dry-cured "lacón" samples from pigs finished with concentrate, mixed diet and chestnut, 54, 58 and 62 volatile compounds were detected, respectively. The most abundant group of flavour compounds at the end of the manufacturing process was hydrocarbons in the three feeding systems, followed by aldehydes, ketones and alcohols. Discriminant analysis selected six variables (dodecane, butadienol, pentenol, 2-pentenal, decen-3-ona and pyridine-2-methyl) and calculated two discriminating functions which allowed verification of chestnut in the finishing diet. PMID:23911930

  15. Synthesis and Size-Separation of Colloidally-Stable Silicon Nanocrystals for the Investigation of their Size-Dependent Optical Properties

    NASA Astrophysics Data System (ADS)

    Mastronardi, Melanie

    Silicon nanocrystals (ncSi) possess unique optical properties that vary predictably with crystal size, which means they can be tailored to suit specific requirements for use in optoelectronic devices and biological applications. The work presented in this thesis outlines contributions made in developing size-separation methods to obtain uniform-sized samples of colloidally-stable ncSi from non-uniform ensembles, which result from most common syntheses that produce colloidally-stable particles. Non-uniform samples of ncSi were prepared using the straightforward thermal processing of sol-gel glasses, followed by HF etching to liberate hydride-capped ncSi from an encapsulating matrix. Thermal hydrosilylation was employed to passivate the ncSi surface with both allylbenzene and 1-decene. Density gradient ultracentrifugation and size-selective precipitation methods were used to isolate size-separated ncSi, which enabled definitive characterization of size-dependent optical properties including photoluminescence (PL), PL absolute quantum yields, and PL lifetimes. A detailed investigation of the chemical reactivity of allylbenzene-capped ncSi with different gaseous atmospheres as probed by in situ luminescence spectroscopy, conducted under both continuous and intermittent illumination, helped elucidate the roles of O2, H2O and mixtures of O2/H 2O, with respect to oxidation of ncSi as a function of size. The results presented in this thesis have played a crucial role towards obtaining a complete understanding of ncSi, a most promising material, and providing vital information that will aid in developing and tailoring perceived applications in advanced materials and biomedical devices.

  16. Metabolomic analysis of breath volatile organic compounds reveals unique breathprints in children with inflammatory bowel disease: A pilot study

    PubMed Central

    Patel, Nisha; Alkhouri, Naim; Eng, Katharine; Cikach, Frank; Mahajan, Lori; Yan, Chen; Grove, David; Rome, Ellen S.; Lopez, Rocio; Dweik, Raed A.

    2014-01-01

    Background Breath testing is becoming an important diagnostic method to evaluate many disease states. In light of rising healthcare costs, is important to develop a simple non-invasive tool to potentially identify pediatric patients who need endoscopy for suspected inflammatory bowel disease (IBD). Aim The primary aim of this study was to analyze exhaled volatile organic compounds (VOCs) to evaluate for the presence of a unique breath pattern to differentiate pediatric patients with (IBD) from healthy controls. Methods A cross-sectional, single-center study included pediatric IBD patients and healthy controls (age range, 5-21 years). The diagnosis of IBD was confirmed by endoscopic, histologic, and radiographic data. Exhaled breath was collected and analyzed using a selective ion flow tube mass spectroscopy (SIFT-MS) to identify new markers or patterns of IBD. Results 117 patients (62 with IBD and 55 healthy controls) were included in the study. Linear discriminant analysis and principle component analysis of mass scanning ion peak data demonstrated 21 pre-selected VOCs correctly classify patients with IBD or as healthy controls; p < 0.0001. Multivariable logistic regression analysis further showed 3 specific VOCs (1-octene, 1-decene, (E)-2-nonene) had excellent accuracy for predicting the presence of IBD with an area under the curve (AUC) of 0.96 (95% CI: 0.93, 0.99). No significant difference in VOCs was found between patients with Crohn's disease or ulcerative colitis and no significant correlation was seen with disease activity. Conclusion This pilot data supports the hypothesis that a unique breathprint potentially exists for pediatric IBD in the exhaled metabolome. PMID:25041596

  17. Development of Methodologies For The Analysis of The Efficiency of Flood Reduction Measures In The Rhine Basin On The Basis of Reference Floods (deflood)

    NASA Astrophysics Data System (ADS)

    Krahe, P.; Herpertz, D.; Buiteveld, H.; Busch, N.; Engel, H.; Helbig, A.; Naef, F.; Wilke, K.

    After some years of extreme flooding in the 1990s extended efforts were made to im- prove flood protection by means of an integrated river basin management. Part of this strategy is the implementation of decentralised flood reduction measures (FRM). With this in mind, the CHR/IRMA-SPONGE Project DEFLOOD was initiated. By estab- lishing a set of methodological tools this project aims at making a step further towards a quantitative hydrological evaluation of the effects of local FRM on flood generation in large river basins. The basin of the River Mosel and in particular, the basin of its tributary Saar served as case study area for testing the methodological approach. A framework for an integrated river basin modelling approach (FIRM U Flood Reduc- tion) based on generation of hydrometeorological reference conditions, precipitation- runoff modelling and flood routing procedures was set up. In this approach interfaces to incorporate the results of scenario calculations by meso-scale hydrological mod- elling are defined in order to study the downstream propagation of the effect of decen- tralised flood reduction measures including the potential retention along minor rivers in large rivers. Examples for scenario calculations are given. Based on the experience gained the strategy for the use of the methodological framework within the context of river basin management practice are identified. The application of the methodol- ogy requires a set of actions which has to be installed in the Rhine/Meuse basins. The recommendations suggest that - beside progress in hydrological modelling - a base of knowledge needs to be built up and administered which encompasses hydrologically relevant information on the actual state and prospected developments in the River Rhine basin. Furthermore, problem-oriented hydrological process studies in selected small-scale river basins ought to be carried out. Based on these studies conceptual meso-scale modelling approaches can be improved and

  18. Covalent adducts arising from the decomposition products of lipid hydroperoxides in the presence of cytochrome C

    PubMed Central

    Williams, Michelle V.; Wishnok, John S.; Tannenbaum, Steven R.

    2008-01-01

    Polyunsaturated fatty acids can be converted to lipid hydroperoxides through non-enzymatic and enzymatic pathways. The prototypic ω-6 lipid hydroperoxide 13-hydroperoxy-octadecadienoic acid (13-HPODE) decomposes homolytically to form highly reactiveα,β-unsaturated aldehydes, such as 9,12-dioxo-10(E)-dodecenoic acid (DODE), 4-oxo-2(E)-nonenal (ONE), 4,5-epoxy-2(E)-decenal (EDE), and 4-hydroxy-2(E)-nonenal (HNE), that can form covalent adducts with DNA. Both 4-oxo-2(E)-nonenal and 4-hydroxy-2(E)-nonenal can also modify proteins to form products that can potentially serve as biomarkers of lipid hydroperoxide-mediated macromolecule damage. In this study cytochrome C was used to identify and characterize the modification sites individually for each of these aldehydes and also to determine the most abundant adduct formed following decomposition of 13-HPODE. The adducts were characterized by ESI-TOF/MS analysis of the intact proteins and by a combination of ESI-ion-trap/MSn and quadrupole-TOF/MS/MS analysis of the tryptic and chymotryptic peptides. The major adducts included an HNE-His Michael adduct on H33, EDE-Lys adducts on K7 and K8, ONE-Lys ketoamide adducts on K5, K7, and K8, an apparent ONE-Lys Michael adduct on K5, and DODE-Lys carboxyl ketoamide adducts on K86 and K87. DODE was the most reactive aldehyde toward cytochrome C. The major adduct from this reaction was analogous to the most abundant adduct resulting from the decomposition of 13-HPODE in the presence of cytochrome C. PMID:17407328

  19. Characterization of Halyomorpha halys (brown marmorated stink bug) biogenic volatile organic compound emissions and their role in secondary organic aerosol formation.

    PubMed

    Solomon, Danielle; Dutcher, Dabrina; Raymond, Timothy

    2013-11-01

    The formation of aerosols is a key component in understanding cloud formation in the context of radiative forcings and global climate modeling. Biogenic volatile organic compounds (BVOCs) are a significant source of aerosols, yet there is still much to be learned about their structures, sources, and interactions. The aims of this project were to identify the BVOCs found in the defense chemicals of the brown marmorated stink bug Halymorpha halys and quantify them using gas chromatography-mass spectrometry (GC/MS) and test whether oxidation of these compounds by ozone-promoted aerosol and cloud seed formation. The bugs were tested under two conditions: agitation by asphyxiation and direct glandular exposure. Tridecane, 2(5H)-furanone 5-ethyl, and (E)-2-decenal were identified as the three most abundant compounds. H. halys were also tested in the agitated condition in a smog chamber. It was found that in the presence of 100-180 ppm ozone, secondary aerosols do form. A scanning mobility particle sizer (SMPS) and a cloud condensation nuclei counter (CCNC) were used to characterize the secondary aerosols that formed. This reaction resulted in 0.23 microg/ bug of particulate mass. It was also found that these secondary organic aerosol particles could act as cloud condensation nuclei. At a supersaturation of 1%, we found a kappa value of 0.09. Once regional populations of these stink bugs stablilize and the populations estimates can be made, the additional impacts of their contribution to regional air quality can be calculated. PMID:24344570

  20. Talbot conditions, Talbot resonators, and first-order systems.

    PubMed

    Fernández-Pousa, Carlos R; Flores-Arias, María Teresa; Bao, Carmen; Pérez, María Victoria; Gómez-Reino, Carlos

    2003-04-01

    A study of first-order Talbot resonators is presented. The general conditions for Talbot effect in ABCD systems are determined. These conditions are applied to the computation of the diffraction overlapping coefficients between array Gaussian emitters in a general first-order Talbot resonator. Relations on the ray-transfer matrix to generate the symmetric and the totally antisymmetric supermodes of the array are derived. These relations generalize the free-space, round-trip lengths of 1/2 and 1/4 of the Talbot distance. A new type of resonator based on a plano-convex gradient-index rod is proposed. PMID:12683489

  1. Orientational order of some liquid crystal/dye mixtures obtained from optical birefringence

    NASA Astrophysics Data System (ADS)

    Bielejewska, Natalia

    2016-04-01

    This study presents optical birefringence measurements as a function of temperature for the liquid crystal/dye mixtures. The optical birefringence of the liquid crystals used in liquid crystal displays technology is related to the order parameter , which is crucial from the development point of view. The properties of the dyes (4-dimethylamino-4‧-nitrostilbene and N,N‧-bis(2,5-di-tert-buthylphenyl)-3,4,9,10-perylenedicarboximide) as a guest molecule are tested over the whole region of nematic phase occurrence by three different methods: measurement with use of the plano-convex lens, Berek's compensator and photoelastic modulator.

  2. Fabrication of microlens arrays in photosensitive glass by femtosecond laser direct writing

    NASA Astrophysics Data System (ADS)

    Lin, C. H.; Jiang, L.; Chai, Y. H.; Xiao, H.; Chen, S. J.; Tsai, H. L.

    2009-12-01

    This article reports the fabrication of high-fill-factor plano-convex cylindrical and spherical microlens arrays horizontally and vertically embedded in a photosensitive Foturan glass chip by femtosecond (fs) laser micromachining. The microlens arrays were fabricated by modifying the microstructure of Foturan glass using fs laser direct writing followed by thermal treatment, wet etching, and additional annealing. The focusing ability and image quality of the microlens arrays were examined, showing that the lens arrays not only can focus light well but also provide an imaging capability that holds great potential for lab-on-a-chip applications.

  3. Horizontally staggered lightguide solar concentrator with lateral displacement tracking for high concentration applications.

    PubMed

    Ma, Hongcai; Wu, Lin

    2015-07-10

    We present the design of a horizontally staggered lightguide solar concentrator with lateral displacement tracking for high concentration applications. This solar concentrator consists of an array of telecentric primary concentrators, a horizontally staggered lightguide layer, and a vertically tapered lightguide layer. The primary concentrator is realized by two plano-aspheric lenses with lateral movement and maintains a high F-number over an angle range of ±23.5°. The results of the simulations show that the solar concentrator achieves a high concentration ratio of 500× with ±0.5° of acceptance angle by a single-axis tracker and dual lateral translation stages. PMID:26193396

  4. Brief history of electronic stereoscopic displays

    NASA Astrophysics Data System (ADS)

    Lipton, Lenny

    2012-02-01

    A brief history of recent developments in electronic stereoscopic displays is given concentrating on products that have succeeded in the market place and hence have had a significant influence on future implementations. The concentration is on plano-stereoscopic (two-view) technology because it is now the dominant display modality in the marketplace. Stereoscopic displays were created for the motion picture industry a century ago, and this technology influenced the development of products for science and industry, which in turn influenced product development for entertainment.

  5. Como Lo Hago Yo: Tratamiento Quirurgico Del Mielomeningocele

    PubMed Central

    Portillo, Santiago

    2014-01-01

    En Argentina hay plan de fortificación con ácido fólico. Diagnostico prenatal no siempre es correcto. Cierre según técnica. Cerramos músculo. No favorecemos corpectomía temprana en casos de cifosis. Suturamos la plaqueta. Cerramos el plano muscular. Hidrocefalia: Válvula de derivación, generalmente dentro de los dos primeros meses. Ventriculostomía no está indicada. Chiari II. Laminectomia cervical alta. Siringomielia: Derivación desde la cavidad al peritoneo. PMID:24791219

  6. [Cancer of the larynx in patients under 40 years of age].

    PubMed

    Kozuch-Gdak, W; Peszyński, J; Boguszewska, D

    1990-01-01

    440 patients with the plano-epithelial laryngeal cancer were radically treated by radiotherapy in Oncologic Department ZOZ in Lublin during the years 1976-1985. Among them were 23 (5.2%) "young" patients, aged below 40. In this group 10 patients (43%) revealed the first grade of clinical stage of the disease, whereas in remaining material there were 25% of cases in the first grade. The therapeutic effects in "young" group were the same as in the rest of cases. The percentage of "young" cancer patients became greater during the time: in 1976-80-4.1%, in 1981-85-6.1%. PMID:2255555

  7. Longest follow-up of in situ working Bjork Shiley valve: 42-year follow-up.

    PubMed

    Soofi, Muhammad A; Ignaszewski, Maya T; Ashton, Thomas H; Miyagishima, Robert T

    2016-03-01

    The Bjork Shiley valve (BSV) is considered as the pioneer among modern disc valves, and eventually evolved into a reliable prosthesis after considerable research and multiple modifications. Various case reports have been published with follow-up of different types of BSV. We are reporting the longest follow-up ever published of a plano-convex type of BSV. Our patient's valve was implanted in 1973 due to a congenital bicuspid aortic valve with concomitant severe, symptomatic aortic stenosis, discovered at the age of 27. She presented with exertional dyspnoea, syncope and chest pain; however, her cardiovascular status remained stable and these symptoms abated after successful valve replacement at the age of 34. She is now 77 years old with no limitations in her activities and is able to walk a few miles most days of the week. Her echocardiograms throughout the decades have shown acceptable gradients across the aortic prosthesis without evidence of haemolysis. Our case report includes a summary of the patient with a discussion of the evidence that supports the durability of the original plano-convex BSV. PMID:26686528

  8. Poly(dimethylsiloxane) microlens array integrated with microfluidic channel for fluorescence spectroscopy detection

    NASA Astrophysics Data System (ADS)

    Rujihan, Suparat; Damrongsak, Badin; Kittidachachan, Pattareeya

    2013-06-01

    Fluorescence spectroscopy detection has been commonly used in chemical and biochemical applications as it provides a good reliability and high sensitivity. Commercially available fluorescence spectroscopy system is typically bulky and expensive, hence making it inconvenience for on-site measurement which requires portable systems. However, the drawback of small devices is that it has a low detection volume, resulting in low fluorescence signal. In this paper, we report a microfluidic channel implemented with a microlens array for enhancing the performance of fluorescence spectroscopy detection. The microlens array was used to focus an excitation light onto the microchannel, thus expecting the increase in fluorescence detection signal. Both microchannels and microlens arrays were individually fabricated from poly-dimethylsiloxane (PDMS) using low-cost printed-circuit-board master molds. The fabrication and characterization of PDMS-based microlens arrays are discussed. In short, the microlens in plano-convex shape was designed with diameters of 700, 800 and 900 microns. The fabricated microlens arrays were characterized for radius of curvatures, SAGs and focal lengths. The plano-convex microlens array was then integrated into a microfluidic system in order to investigate the overall performance of fluorescence spectroscopy detection. Experiments were conducted with two fluorescence dyes, i.e. Rhodamine 6G and Coumarin 153. The preliminary results revealed that the PDMS microlens array implemented on the designed system shows potential for improving excitation and emission light intensity and, as a consequence, signal to background ratio of the fluorescence spectroscopy detection.

  9. Characteristics of optimized fibre-optic ultrasound receivers for minimally invasive photoacoustic detection

    NASA Astrophysics Data System (ADS)

    Zhang, Edward Z.; Beard, Paul C.

    2015-03-01

    A range of miniature (125μm o.d.) fibre optic ultrasound sensors based on the use of interferometric polymer optical cavities has been developed for minimally invasive photoacoustic imaging and sensing applications. It was observed that by careful selection of both the fibre tip and cavity geometry it is possible to achieve exceptional acoustic performance. Specifically, rounding the tip of the fibre to remove the presence of sharp diffractive boundaries enables a well behaved frequency response along with a near omnidirectional response at frequencies in the tens of MHz range to be achieved. The use of a plano-convex rather than a planar cavity provides high finesse and therefore detection sensitivity. Thus, by using a plano-convex cavity formed at the tip of radiused single mode fibre it was possible to realise a miniature ultrasound detector with a bandwidth of 80MHz, a noise-equivalent pressure of 40Pa (over a 20MHz measurement bandwidth) and a near omnidirectional response at frequencies as high as 30MHz. These characteristics suggest this type of sensor could find applications in interventional medicine for guiding needles or catheters, as mechanically scanned photoacoustic imaging probes or in laser scanning OR-PAM.

  10. Microchip laser operation of Tm,Ho:KLu(WO₄)₂ crystal.

    PubMed

    Loiko, Pavel; Serres, Josep Maria; Mateos, Xavier; Yumashev, Konstantin; Kuleshov, Nikolai; Petrov, Valentin; Griebner, Uwe; Aguiló, Magdalena; Díaz, Francesc

    2014-11-17

    A microchip laser is realized on the basis of a monoclinic Tm,Ho-codoped KLu(WO₄)₂crystal cut for light propagation along the Ng optical indicatrix axis. This crystal cut provides positive thermal lens with extremely weak astigmatism, S/M = 4%. High sensitivity factors, M = dD/dP(abs), of 24.9 and 24.1 m(-1)/W for the mg- and pg- tangential planes are calculated with respect to the absorbed pump power. Such thermo-optic behavior is responsible for mode stabilization in the plano-plano microchip laser cavity, as well as the demonstrated perfect circular beam profile (M(2) < 1.1). Maximum continuous-wave output power of 450 mW is obtained with a slope efficiency of 31%. A set of output couplers is employed to achieve lasing in the spectral range of 2060-2096 nm. The increase of output coupler transmission results in deterioration of the laser performance attributed to the increased up-conversion losses. PMID:25402038

  11. Variable-focal lens using electroactive polymer actuator

    NASA Astrophysics Data System (ADS)

    Vunder, V.; Punning, A.; Aabloo, A.

    2011-03-01

    The paper describes a simple and cost-effective design and fabrication process of a liquid-filled variable-focal lens. The lens was made of soft polymer material, its shape and curvature can be controlled by hydraulic pressure. An electroactive polymer is used as an actuator. A carbon-polymer composite (CPC) was used. The device is composed of elastic membrane upon a circular lens chamber, a reservoir of liquid, and a channel between them. It was made of three layers of polydimethylsiloxane (PDMS), bonded using the partial curing technique. The channels and reservoir were filled with incompressible liquid after curing process. A CPC actuator was mechanically attached to reservoir to compress or decompress the liquid. Squeezing the liquid between the reservoir and the lens chamber will push the membrane inward or outward resulting in the change of the shape of the lens and alteration of its focal length. Depending on the pressure the lens can be plano-convex or plano-concave or even switch between the two configurations. With only a few minor modifications it is possible to fabricate bi-convex and bi-concave lenses. The lens with a 1 mm diameter and the focal length from infinity to 17 mm is reported. The 5x15mm CPC actuator with the working voltage of only up to +/-2.5 V was capable to alter the focal length within the full range of the focal length in 10 seconds.

  12. Spectral performance of monolithic holmium and thulium lasers

    NASA Technical Reports Server (NTRS)

    Storm, Mark E.

    1991-01-01

    Fabry-Perot resonators have been used to demonstrate single-mode lasing of holmium and neodymium YAG. The previous demonstration in the holmium laser required TE cooling the crystal to -15 C in order to achieve threshold. The present study extends that result, demonstrating +25 C operation in a 1-mm thick plano/plano resonator. The experimental configuration of lasing both the holmium and thulium lasers used a 500-mW diode laser which was collimated, circularized, and focused into a beam radius of 60 microns. The single-frequency lasing spectrum of the holmium laser is shown. By adjusting the mirror reflectivity, the ability to control the laser's wavelength is demonstrated. This laser operated with 11 mW of optical power, a 57-percent slope efficiency, and 120-mW threshold vs absorbed diode power laser for the 60-micron beam radius. The thulium laser operated very efficiently at room temperature, but on seven longitudinal modes. The Tm:TAG laser exhibits typical characteristics of spatial hole burning not seen in the Ho:Tm:YAG for flat/flat resonators.

  13. Practice Trends in the Use of Extracorporeal Treatments for Poisoning in Four Countries.

    PubMed

    Ghannoum, Marc; Lavergne, Valery; Gosselin, Sophie; Mowry, James B; Hoegberg, Lotte C G; Yarema, Mark; Thompson, Margaret; Murphy, Nancy; Thompson, John; Purssell, Roy; Hoffman, Robert S

    2016-01-01

    Extracorporeal treatments (ECTRs) such as hemodialysis (HD), enhance the elimination of a small number of toxins. Changes in overdose trends, prescribing practices, antidotes, and dialysis techniques may alter the indications and rates of ECTR use over time. This study analyzed trends in ECTR for poisonings in four countries. A retrospective study of national poison center databases from the United States, Denmark, United Kingdom, and five regional databases within Canada was performed. All cases of patients receiving an ECTR were included. ECTR cases were totalled annually and reported as annual rates per 100,000 exposures with stratification per types of ECTR and toxins. The data collection varied by countries. United States, 1985-2014; United Kingdom, 2011-2013; Denmark, 2005-2014, and regions of Canada as follows: Alberta, 1991-2015; Saskatchewan, 2001-2015; Nova Scotia-PEI, 2006-2015; Quebec, 2008-2014; Ontario-Manitoba, 2009-2015; British Columbia, 2012-2015. During the study period, the total number of ECTRs and rates per 100,000 exposures, respectively, were: United States, 40,258 and 65.7; United Kingdom, 343 and 232.6; Denmark, 616 and 305.5; Canada, 2709 and 177.5; case rates increased over time for the United States, Denmark, and Canada, but decreased in the United Kingdom. Across the United States and Denmark, HD was the preferred modality used. Toxins for which ECTR was most often used were: United States, ethylene glycol; Canada, methanol; United Kingdom, ethylene glycol; Denmark, salicylates. A high number of ECTRs were performed for atypical toxins such as acetaminophen and benzodiazepines. These data demonstrate a growing use of HD for poisoning with significant regional variations in the overall rates and indications. PMID:26551956

  14. Global reductions in seafloor biomass in response to climate change.

    PubMed

    Jones, Daniel O B; Yool, Andrew; Wei, Chih-Lin; Henson, Stephanie A; Ruhl, Henry A; Watson, Reg A; Gehlen, Marion

    2014-06-01

    Seafloor organisms are vital for healthy marine ecosystems, contributing to elemental cycling, benthic remineralization, and ultimately sequestration of carbon. Deep-sea life is primarily reliant on the export flux of particulate organic carbon from the surface ocean for food, but most ocean biogeochemistry models predict global decreases in export flux resulting from 21st century anthropogenically induced warming. Here we show that decadal-to-century scale changes in carbon export associated with climate change lead to an estimated 5.2% decrease in future (2091-2100) global open ocean benthic biomass under RCP8.5 (reduction of 5.2 Mt C) compared with contemporary conditions (2006-2015). Our projections use multi-model mean export flux estimates from eight fully coupled earth system models, which contributed to the Coupled Model Intercomparison Project Phase 5, that have been forced by high and low representative concentration pathways (RCP8.5 and 4.5, respectively). These export flux estimates are used in conjunction with published empirical relationships to predict changes in benthic biomass. The polar oceans and some upwelling areas may experience increases in benthic biomass, but most other regions show decreases, with up to 38% reductions in parts of the northeast Atlantic. Our analysis projects a future ocean with smaller sized infaunal benthos, potentially reducing energy transfer rates though benthic multicellular food webs. More than 80% of potential deep-water biodiversity hotspots known around the world, including canyons, seamounts, and cold-water coral reefs, are projected to experience negative changes in biomass. These major reductions in biomass may lead to widespread change in benthic ecosystems and the functions and services they provide. PMID:24382828

  15. [Fight against tuberculosis in the world].

    PubMed

    El Kamel, A; Joobeur, S; Skhiri, N; Cheikh Mhamed, S; Mribah, H; Rouatbi, N

    2015-01-01

    Tuberculosis (TB) in a major health problem in the world. WHO and its partners especially, the stop TB partnership launched numerous strategies against TB especially in the 1990. Strategy DOTS (directly observed therapy short course) was launched in 1995. One main key was the direct supervision of drug intake by patients. Progress was achieved but it was insufficient. A new strategy called "Stop TB Strategy 2006-2015" was launched in 2006 in the context of Millennium Development Goals (MDG) elaborated by United Nations. The common goals were to halt and start to reverse the incidence of TB, reduce the prevalence and death rate by 50% compared to their level in 1990 by 2015 to eliminate TB as a public health problem by 2050. The end of 2010 marks the mid-point of the Global Plan and is an obvious time to update it and take into account actual progress with a focus on the 2015 to reach goals. So an updated Global Plan to stop TB 2011-2015, was launched. Expected progress and targets were defined for 2015, in diagnosis and treatment, in co-infection TB/HIV, in drug-resistant TB and achievements expected in new tests for diagnosis, new medications, new vaccines and new regimens with shorter duration of treatment. WHO and partners have started discussions to define the new post 2015 strategy to TB control and elimination. Risk factors (diabetes, malnutrition, tobacco smoke…) and socioeconomic factors, which are associated with TB, should be included in the new strategy to eliminate TB in 2050. PMID:24878188

  16. Back-trajectory modelling and DNA-based species-specific detection methods allow tracking of fungal spore transport in air masses.

    PubMed

    Grinn-Gofroń, Agnieszka; Sadyś, Magdalena; Kaczmarek, Joanna; Bednarz, Aleksandra; Pawłowska, Sylwia; Jedryczka, Malgorzata

    2016-11-15

    Recent advances in molecular detection of living organisms facilitate the introduction of novel methods to studies of the transport of fungal spores over large distances. Monitoring the migration of airborne fungi using microscope based spore identification is limited when different species produce very similar spores. In our study, DNA-based monitoring with the use of species-specific probes allowed us to track the aerial movements of two important fungal pathogens of oilseed rape (Brassica napus L.), i.e., Leptosphaeria maculans and Leptosphaeria biglobosa, which have identical spore shape and size. The fungi were identified using dual-labelled fluorescent probes that were targeted to a β-tubulin gene fragment of either Leptosphaeria species. Spore identification by Real-Time PCR techniques capable of detecting minute amounts of DNA of selected fungal species was combined with back-trajectory analysis, allowing the tracking of past movements of air masses using the Hybrid Single Particle Lagrangian Integrated Trajectory model. Over a study period spanning the previous decade (2006-2015) we investigated two specific events relating to the long distance transport of Leptosphaeria spp. spores to Szczecin in North-West Poland. Based on the above mentioned methods and the results obtained with the additional spore sampler located in nearby Szczecin, and operating at the ground level in an oilseed rape field, we have demonstrated that on both occasions the L. biglobosa spores originated from the Jutland Peninsula. This is the first successful attempt to combine analysis of back-trajectories of air masses with DNA-based identification of economically important pathogens of oilseed rape in Europe. In our studies, the timing of L. biglobosa ascospore dispersal in the air was unlikely to result in the infection of winter oilseed rape grown as a crop plant. However, the fungus could infect other host plants, such as vegetable brassicas, cruciferous weeds, spring rapeseed

  17. Extreme rainfall analysis based on precipitation events classification in Northern Italy

    NASA Astrophysics Data System (ADS)

    Campo, Lorenzo; Fiori, Elisabetta; Molini, Luca

    2016-04-01

    the raingauges observation in northern Italy for the period 2006-2015.

  18. Did we reach the 2005 targets for tuberculosis control?

    PubMed

    Dye, Christopher; Hosseini, Mehran; Watt, Catherine

    2007-05-01

    The World Health Assembly set targets to detect by 2005 at least 70% of all new sputum smear-positive cases arising each year and to cure at least 85% of these cases. The national tuberculosis (TB) control programmes of 199 countries reported that in 2005, 2.3 million new smear-positive cases were diagnosed under WHOs DOTS strategy, out of an estimated 3.9 million (95% confidence limit (CL) 3.4 million to 4.4 million) new smear-positive cases arising in that year, a global case detection rate of 60% (95% CL 52% to 69%). Of 2.1 million new smear-positive patients registered for treatment in 2004, 84% had successful outcomes. Of the regions, only the WHO Western Pacific Region reached both targets, with case detection and treatment success rates of 76% and 91%, respectively; South-East Asia reached the treatment success target with a rate of 87%. In relation to countries, WHO estimates that 67 achieved the target detection rates and 57 achieved the target for treatment success, with 26 - including high-burden countries China, the Philippines and Viet Nam - achieving both targets. DOTS programmes diagnosed more than 26 million patients (all forms of TB) in 1995-2005. Building on this success, the Global Plan to Stop TB 2006-2015, describes the actions needed to implement WHOs new Stop TB Strategy over the coming decade to reduce TB incidence, prevalence and deaths in line with the Millennium Development Goals. PMID:17639221

  19. Nearly a Decade of CALIPSO Observations of Asian and Saharan Dust Properties Near Source and Transport Regions

    NASA Technical Reports Server (NTRS)

    Omar, Ali H.; Liu, Z.; Tackett, J.; Vaughan, M.; Trepte, C.; Winker, D.; H. Yu,

    2015-01-01

    The lidar on the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) mission, makes robust measurements of dust and has generated a length of record that is significant both seasonally and inter-annually. We exploit this record to determine a multi-year climatology of the properties of Asian and Saharan dust, in particular seasonal optical depths, layer frequencies, and layer heights of dust gridded in accordance with the Level 3 data products protocol, between 2006-2015. The data are screened using standard CALIPSO quality assurance flags, cloud aerosol discrimination (CAD) scores, overlying features and layer properties. To evaluate the effects of transport on the morphology, vertical extent and size of the dust layers, we compare probability distribution functions of the layer integrated volume depolarization ratios, geometric depths and integrated attenuated color ratios near the source to the same distributions in the far field or transport region. CALIPSO is collaboration between NASA and Centre National D'études Spatiales (CNES), was launched in April 2006 to provide vertically resolved measurements of cloud and aerosol distributions. The primary instrument on the CALIPSO satellite is the Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP), a near-nadir viewing two-wavelength polarization-sensitive instrument. The unique nature of CALIOP measurements make it quite challenging to validate backscatter profiles, aerosol type, and cloud phase, all of which are used to retrieve extinction and optical depth. To evaluate the uncertainty in the lidar ratios, we compare the values computed from dust layers overlying opaque water clouds, considered nominal, with the constant lidar ratio value used in the CALIOP algorithms for dust. We also explore the effects of noise on the CALIOP retrievals at daytime by comparing the distributions of the properties at daytime to the nighttime distributions.

  20. 9+ Years of CALIPSO PSC Observations: An Evolving Climatology

    NASA Technical Reports Server (NTRS)

    Pitts, Michael C.; Poole, Lamont R.

    2015-01-01

    record from 2006- 2015.

  1. On the Seasonal Occurrence and Abundance of the Zika Virus Vector Mosquito Aedes Aegypti in the Contiguous United States

    PubMed Central

    Monaghan, Andrew J.; Morin, Cory W.; Steinhoff, Daniel F.; Wilhelmi, Olga; Hayden, Mary; Quattrochi, Dale A.; Reiskind, Michael; Lloyd, Alun L.; Smith, Kirk; Schmidt, Chris A.; Scalf, Paige E.; Ernst, Kacey

    2016-01-01

    Introduction: An ongoing Zika virus pandemic in Latin America and the Caribbean has raised concerns that travel-related introduction of Zika virus could initiate local transmission in the United States (U.S.) by its primary vector, the mosquito Aedes aegypti. Methods: We employed meteorologically driven models for 2006-2015 to simulate the potential seasonal abundance of adult Aedes aegypti for fifty cities within or near the margins of its known U.S. range. Mosquito abundance results were analyzed alongside travel and socioeconomic factors that are proxies of viral introduction and vulnerability to human-vector contact.     Results: Meteorological conditions are largely unsuitable for Aedes aegypti over the U.S. during winter months (December-March), except in southern Florida and south Texas where comparatively warm conditions can sustain low-to-moderate potential mosquito abundance. Meteorological conditions are suitable for Aedes aegypti across all fifty cities during peak summer months (July-September), though the mosquito has not been documented in all cities. Simulations indicate the highest mosquito abundance occurs in the Southeast and south Texas where locally acquired cases of Aedes-transmitted viruses have been reported previously. Cities in southern Florida and south Texas are at the nexus of high seasonal suitability for Aedes aegypti and strong potential for travel-related virus introduction. Higher poverty rates in cities along the U.S.-Mexico border may correlate with factors that increase human exposure to Aedes aegypti.     Discussion: Our results can inform baseline risk for local Zika virus transmission in the U.S. and the optimal timing of vector control activities, and underscore the need for enhanced surveillance for Aedes mosquitoes and Aedes-transmitted viruses. PMID:27066299

  2. Global Immunization Vision and Strategy (GIVS): a mid-term analysis of progress in 50 countries.

    PubMed

    Kamara, Lidija; Lydon, Patrick; Bilous, Julian; Vandelaer, Jos; Eggers, Rudi; Gacic-Dobo, Marta; Meaney, William; Okwo-Bele, Jean-Marie

    2013-01-01

    Within the overall framework set out in the Global Immunization Vision and Strategy (GIVS) for the period 2006-2015, over 70 countries had developed comprehensive Multi-Year Plans (cMYPs) by 2008, outlining their plans for implementing the GIVS strategies and for attaining the GIVS Goals at the midpoint in 2010 or earlier. These goals are to: (1) reach ≥90% and ≥80% vaccination coverage at national and district level, respectively; and (2) reduce measles-related mortality by 90% compared with the 2000 level. Fifty cMYPs were analysed along the four strategic areas of the GIVS: (1) protecting more people in a changing world; (2) introducing new vaccines and technologies; (3) integrating immunization, other health interventions and surveillance in the health system context; and (4) immunizing in the context of global interdependence. By 2010, all 50 countries planned to have introduced hepatitis B (HepB) vaccine, 48 the Haemophilus influenzae type B (Hib) vaccine and only a few countries had firm plans to introduce pneumococcal or rotavirus vaccines. Countries seem to be inadequately prepared in terms of cold-chain requirements to deal with the expected increases in storage that will be required for vaccines, and in making provisions to establish a corresponding surveillance system for planned new vaccine introductions. Immunization contacts are used to deliver other health interventions, especially in the countries in the World Health Organization (WHO) Africa Region. The cost for the planned immunization activities will double to U$27 per infant, of which U$5 per infant is the expected shortfall. Global Alliance for Vaccines and Immunization (GAVI) funding is becoming the largest contributor to immunization programmes. PMID:22411879

  3. Anabolic and Catabolic Signaling Pathways in mouse Longissimus Dorsi after 30-day BION-M1 Spaceflight and Subsequent Recovery

    NASA Astrophysics Data System (ADS)

    Mirzoev, Timur; Blottner, Dieter; Shenkman, Boris; Lomonosova, Yulia; Vilchinskaya, Natalia; Nemirovskaya, Tatiana; Salanova, Michele

    The aim of the study was to analyze some of the key markers regulating anabolic and catabolic processes in mouse m. longissimus dorsi, an important back muscle system for trunk stabilization, following 30-day spaceflight and 8-day recovery period. C57/black mice were divided into 3 groups: 1) Vivarium Control (n=7), 2) Flight (n=5), 3) Recovery (n=5). The experiment was carried out in accordance with the rules of biomedical ethics certified by the Russian Academy of Sciences Committee on Bioethics. Using Western-blotting analysis we determined the content of IRS-1, p-AMPK, MURF-1 and eEF2 in m. longissimus dorsi. The content of IRS-1 in mice m. longissimus dorsi after the 30-day flight did not differ from the control group, however, in the Recovery group IRS-1 level was 80% higher (p<0.05) as compared to Control. Phospho-AMPK content remained unchanged. In the Recovery group there was an increase of eEF2 by 75% compared to the Control (p<0.05). After spaceflight MuRF-1 content was increased more than 2 times compared to the control animals. Thus, our findings showed that the work of the IRS-1 - dependent signaling pathway is only active in the recovery period. The content of the ubiquitin-ligase MURF-1 that takes parts in degrading myosin heavy chain was increased after the spaceflight, however, after 8-day recovery period MURF-1 level did not exceed the control indicating normalization of protein degradation in m. longissimus dorsi. The work was supported by the program of basic research of RAS and Federal Space Program of Russia for the period of 2006-2015.

  4. Angiotensin II modification by decomposition products of linoleic acid-derived lipid hydroperoxide.

    PubMed

    Takahashi, Ryo; Goto, Takaaki; Oe, Tomoyuki; Lee, Seon Hwa

    2015-09-01

    Polyunsaturated fatty acids are highly susceptible to oxidation induced by reactive oxygen species and enzymes, leading to the formation of lipid hydroperoxides. The linoleic acid (LA)-derived hydroperoxide, 13-hydroperoxyoctadecadienoic acid (HPODE) undergoes homolytic decomposition to reactive aldehydes, 4-oxo-2(E)-nonenal (ONE), 4-hydroxy-2(E)-nonenal, trans-4,5-epoxy-2(E)-decenal (EDE), and 4-hydroperoxy-2(E)-nonenal (HPNE), which can covalently modify peptides and proteins. ONE and HNE have been shown to react with angiotensin (Ang) II (DRVYIHPF) and modify the N-terminus, Arg(2), and His(6). ONE-derived pyruvamide-Ang II (Ang P) alters the biological activities of Ang II considerably. The present study revealed that EDE and HPNE preferentially modified the N-terminus and His(6) of Ang II. In addition to the N-substituted pyrrole of [N-C4H2]-Ang II and Michael addition products of [His(6)(EDE)]-Ang II, hydrated forms were detected as major products, suggesting considerable involvement of the vicinal dihydrodiol (formed by epoxide hydration) in EDE-derived protein modification in vivo. Substantial amounts of [N-(EDE-H2O)]-Ang II isomers were also formed and their synthetic pathway might involve the tautomerization of a carbinolamine intermediate, followed by intramolecular cyclization and dehydration. The main HPNE-derived products were [His(6)(HPNE)]-Ang II and [N-(HPNE-H2O)]-Ang II. However, ONE, HNE, and malondialdehyde-derived modifications were dominant, because HPNE is a precursor of these aldehydes. A mixture of 13-HPODE and [(13)C18]-13-HPODE (1:1) was then used to determine the major modifications derived from LA peroxidation. The characteristic doublet (1:1) observed in the mass spectrum and the mass difference of the [M+H](+) doublet aided the identification of Ang P (N-terminal α-ketoamide), [N-ONE]-Ang II (4-ketoamide), [Arg(2)(ONE-H2O)]-Ang II, [His(6)(HNE)]-Ang II (Michael addition product), [N-C4H2]-Ang II (EDE-derived N-substituted pyrrole

  5. Co-formation of hydroperoxides and ultra-fine particles during the reactions of ozone with a complex VOC mixture under simulated indoor conditions

    NASA Astrophysics Data System (ADS)

    Fan, Zhihua; Weschler, Charles J.; Han, In-Kyu; Zhang, Junfeng (Jim)

    In this study we examined the co-formation of hydrogen peroxide and other hydroperoxides (collectively presented as H 2O 2*) as well as submicron particles, including ultra-fine particles (UFP), resulting from the reactions of ozone (O 3) with a complex mixture of volatile organic compounds (VOCs) under simulated indoor conditions. The VOC mixture contained 23 compounds, including two terpenes ( d-limonene and α-pinene), two unsaturated alkenes (1-decene and 1-octene), and 19 other saturated organic compounds. These compounds are commonly found in indoor air but their concentrations were higher than typical indoor levels. When O 3 was added to a 25-m 3 controlled environmental facility (CEF) containing the 23 VOC mixture, both H 2O 2* and submicron particles were formed. The 2-h average concentration of H 2O 2* was 1.89±0.30 ppb, and the average total particle number concentration was 46,000±12,000 particles cm -3. A small increase of UFP (0.02-0.1 μm) occurred 5 min after the O 3 addition (17 min after the VOC addition) and a sharp increase of UFP occurred 13 min after the O 3 addition, suggesting homogeneous nucleation. The delayed onset of this event might reflect the time required to achieve saturated concentrations of the condensable organics. When the 2 terpenes were removed from the O 3/23 VOCs mixture, no H 2O 2* or particles were formed, indicating that the reactions of O 3 with the two terpenes were the key processes contributing to the formation of H 2O 2* and submicron particles in the O 3/23 VOCs system. The present study confirmed the findings of a previous study carried out in a real-world office and generated new findings regarding co-formation of UFP. Through a comparative analysis of H 2O 2* yields under different reaction conditions, this study demonstrates that VOCs co-present with the terpenes and O 3 may play a role in producing H 2O 2*.

  6. Ecology of larval mosquitoes, with special reference to Anopheles arabiensis (Diptera: Culcidae) in market-garden wells in urban Dakar, Senegal.

    PubMed

    Robert, V; Awono-Ambene, H P; Thioulouse, J

    1998-11-01

    The urban area of Dakar, Senegal, contains > 5,000 market-garden wells that provide permanent sites for mosquito larvae, in particular Anopheles arabiensis Patton, the major vector of malaria. A study of the bioecology of mosquito larvae was conducted over 1 yr with a monthly visit to 48 of these wells. Overall, 9,589 larvae were collected of which 80.1% were Culicinae and 11.9% Anophelinae. Larvae from stages III and IV (n = 853) were identified to 10 species. An. arabiensis represented 86% of the anophelines collected and An. ziemanni Grunberg 14%. The most common Culicinae species included Aedeomyia africana Neveu-Lemaire, Culex quinquefasciatus Say, and Mimomyia splendens Theobald. Maximum anopheline abundance was observed at the end of the dry season in June, whereas maximum Culicinae abundance was observed at the end of the rainy season in September. Most wells (67%) did not harbor any An. arabiensis larvae and in the remaining 33% the larval abundance was low, averaging 0.54 larvae in stages III-IV per tray sample. To identify factors that determine the abundance of larvae in these wells, a co-inertia (multivariate) analysis was carried out to account for physicochemical variables (depth, turbidity, temperature, pH, conductivity, Na+, Cl-, HCO3-, CO3--, and NO3- concentrations) and biological variables (abundance of mosquito species, predators [e.g., fish, Dytiscidae, Notonectidae, odonates], molluscs [Bulinus and Biomphalaria], and surface plants [water lettuce, Lemna, and filamentous algae]). The co-inertia analysis indicated that the abundance of An. arabiensis was associated with Cx. quinquefasciatus and Cx. decens for the physiochemical data but was not associated with other mosquito species for floro-faunistic data. The conditions associated with abundant An. arabiensis were warm temperature (28-30 degrees C), clear and not too deep water (< 0.5 m), elevated concentrations of HCO3- and CO3--, low concentrations of NO3- and NaCl, low populations of

  7. Metathetical reactions of Re(VII) alkylidene-alkylidyne complexes of the type Re(CR[prime])(CHR[prime])[OCMe(CF[sub 3])[sub 2

    SciTech Connect

    Toreki, R.; Vaughan, G.A.; Schrock, R.R.; Davis, W.M. )

    1993-01-13

    1-Decene and methyl 9-decenoate react with syn- and anti-Re(C-t-Bu)(CH-t-Bu)(OR[sub F6]) to give syn- and anti-Re(C-t-Bu)[CH(CH[sub 2])[sub 7]Me](OR[sub F6])[sub 2] and syn- and anti-Re(C-t-Bu)[CH(CH[sub 2])[sub 7]CO[sub 2]Me](OR[sub F6])[sub 2], respectively (OR[sub F6] = OCMe(CF[sub 3])[sub 2]). The new alkylidene complexes are unstable in the presence of excess terminal olefin and decompose upon attempted isolation. However, vinylferrocene reacts relatively smoothly and reversibly with syn-Re(C-t-Bu)(CH-t-Bu)(OR[sub F6])[sub 2] in a noncoordinating solvent to yield tert-butylethylene and primarily anti-Re(C-t-Bu)(CHFc)(OR[sub F6])[sub 2] (Fe = ferrocenyl). anti-Re(C-t-Bu)(CHFc)(OR[sub F6])[sub 2]. In the presence of THF or dimethoxyethane, complexes of the type syn- or anti-Re(C-t-Bu)(CHR)(OR[sub F6])S[sub 2] (R = Me, Et, Ph; S = THF or 0.5DME) could be prepared in high yield from Re(C-t-Bu)(CH-t-Bu)(OR[sub F6])[sub 2] and CH[sub 2][double bond]CHR. Heteroatom-substituted (O, S, or N) terminal olefins react more rapidly than ordinary olefins with Re(C-t-Bu)(CH-t-Bu)(OR[sub F6])[sub 2] in the presence of THF to yield complexes of the type syn- or anti-Re(C-t-Bu)(CHX)(OR[sub F6])[sub 2](THF)[sub 2] (X = OR, SR, NR[sub 2], or p-dimethylaminophenyl). 2-Pentene or methyl oleate is metathesized in the presence of Re(C-t-Bu)(CH-t-Bu)(OR[sub F6])[sub 2], and intermediate alkylidene complexes can be observed in each case. Addition of 3-hexene to Re(C-t-Bu)(CH-t-Bu)(OR[sub F6])[sub 2] followed by TMEDA yields Re(C-t-Bu)(CHEt)(OR[sub F6])[sub 2](TMEDA). Internal olefins are metathesized only very slowly by Re(C-t-Bu)(CH-t-Bu)(OR[sub F6])[sub 2] in the presence of several equivalents of THF or DME or especially in neat THF or DME. 58 refs., 4 figs., 4 tabs.

  8. Flavour Chemistry of Chicken Meat: A Review

    PubMed Central

    Jayasena, Dinesh D.; Ahn, Dong Uk; Nam, Ki Chang; Jo, Cheorun

    2013-01-01

    Flavour comprises mainly of taste and aroma and is involved in consumers’ meat-buying behavior and preferences. Chicken meat flavour is supposed to be affected by a number of ante- and post-mortem factors, including breed, diet, post-mortem ageing, method of cooking, etc. Additionally, chicken meat is more susceptible to quality deterioration mainly due to lipid oxidation with resulting off-flavours. Therefore, the intent of this paper is to highlight the mechanisms and chemical compounds responsible for chicken meat flavour and off-flavour development to help producers in producing the most flavourful and consistent product possible. Chicken meat flavour is thermally derived and the Maillard reaction, thermal degradation of lipids, and interaction between these 2 reactions are mainly responsible for the generation of flavour and aroma compounds. The reaction of cysteine and sugar can lead to characteristic meat flavour specially for chicken and pork. Volatile compounds including 2-methyl-3-furanthiol, 2-furfurylthiol, methionol, 2,4,5-trimethyl-thiazole, nonanol, 2-trans-nonenal, and other compounds have been identified as important for the flavour of chicken. However 2-methyl-3-furanthiol is considered as the most vital chemical compound for chicken flavour development. In addition, a large number of heterocyclic compounds are formed when higher temperature and low moisture conditions are used during certain cooking methods of chicken meat such as roasting, grilling, frying or pressure cooking compared to boiled chicken meat. Major volatile compounds responsible for fried chicken are 3,5-dimethyl-1,2,4-trithiolanes, 2,4,6-trimethylperhydro-1,3,5-dithiazines, 3,5-diisobutyl-1,2,4-trithiolane, 3-methyl-5-butyl-1,2,4-trithiolane, 3-methyl-5-pentyl-1,2,4-trithiolane, 2,4-decadienal and trans-4,5-epoxy-trans-2-decenal. Alkylpyrazines were reported in the flavours of fried chicken and roasted chicken but not in chicken broth. The main reason for flavour deterioration

  9. Optimization of H3O+/O2+ Dual-mode Ionization in PTR-MS for Simultaneous Detection of Alkanes, Olefins and Aromatic Compounds

    NASA Astrophysics Data System (ADS)

    Amador-Muñoz, O.; Misztal, P. K.; Weber, R.; Drozd, G.; Worton, D. R.; Goldstein, A. H.

    2014-12-01

    Measurements of VOC composition from fossil fuels are analytically challenging because of the complex mixture of hydrocarbons (saturated, unsaturated, aromatics, etc). Speciated chemical measurements typically rely on relatively slow GC separation. Proton transfer reaction mass spectrometry (PTR-MS) is advantageous due to its fast response and high sensitivity. The most common ionization mechanism applied to VOC detection by PTR-MS is proton transfer from hydronium ion (H3O+). However, alkanes cannot be detected using H3O+ ionization chemistry because their proton affinities are too low. Ionization of alkanes is possible via electron transfer and/or hydride abstraction using O2+ or NO+. We used PTR-MS to analyze aromatic, alkene and alkane (linear, branched and cyclic) compounds simultaneously not by switching the ionization agents, but by adjusting the drift tube voltage and optimizing the ratio of H3O+/O2+ produced in the instrument's ion source. The highest detection sensitivity for aromatic and alkene compounds was produced by proton transfer from H3O+, while hydride abstraction by O2+ allowed detection of alkanes. For alkanes, sensitivities ranged from 1.1±0.01 cps/ppbv for n-decane to 74.7±0.25 cps/ppbv for decalin. Sensitivities in O2+ mode were from 6 (Adamantane) to 146 (4-Methyl nonane) times higher than those obtained in H3O+ mode under the same ion source and drift tube voltage conditions. Sensitivities for butyl benzene and 1-decene were 157±0.57 and 66.8±0.21 cps/ppbv, respectively. Sensitivity differences among C10 hydrocarbons are related to their structure, which affects their ionization energies (IE) and hence ease of hydride abstraction. Sensitivities at the parent ion mass were inversely correlated with IE (142 cps/ppbv/eV). This suggests higher electronic stability for cyclic non substituted compounds, followed by cyclic substituted, branch linear and linear C10 hydrocarbons. Although selectivity is a known shortcoming of quadrupole

  10. Desenvolvimento das câmeras de raios-X duros do satélite MIRAX

    NASA Astrophysics Data System (ADS)

    Braga, J.; Rothschild, R.; Staubert, R.; Heise, J.; Remillard, R.; D'Amico, F.; Jablonski, F.; Mejía, J.; Carvalho, H.; Heindl, B.; Matteson, J.; Kendziorra, E.; Wilms, J.; in't Zand, J.; Kuulkers, E.

    2003-08-01

    O MIRAX (Monitor e Imageador de RAios-X) é um projeto de desenvolvimento de um pequeno satélite astronômico de raios-X (~200 kg, ~240 W). A estratégia básica da missão será observar continuamente (~9 meses por ano) a região central (~1000 graus2) do plano Galáctico e realizar estudos espectroscópicos de banda larga (2-200 keV) e alta sensibilidade de um grande conjunto de fontes através de imagens com resolução de ~6'. Isso proporcionará uma cobertura inédita do "espaço de descobertas" através da detecção, localização, identificação e estudo detalhado de fenômenos imprevisíveis, tais como transientes fracos de raios-X, novas rápidas de raios-X e bursts de raios gama, assim como o estudo de fontes com emissão persistente. Neste trabalho apresentamos o projeto das duas câmeras de raios-X duros (CXDs) do MIRAX, que irão operar na faixa de 10 a 200 keV. Cada CXD consistirá de um plano de detectores CZT (Cd0,9Zn0,1Te) de 0,5 mm de resolução espacial e 370 cm2 de área total, e de uma máscara codificada com elementos quadrados de 1,3 mm de lado e 0,5 cm de espessura. A máscara terá dimensões de 315 cm ´ 275 cm e será montada a 700 cm de distância dos detectores. Com essa configuração as CXDs terão 6' de resolução angular e, quando colocadas a um ângulo de 29° entre si, as duas câmeras propiciam um campo totalmente codificado de 39° ´ 6°12' e um campo total de 76° ´ 44°. Serão apresentadas simulações de observações da região do plano Galáctico com o conjunto formado pelas duas CXDs.

  11. Microwave Cavity for Anapole Moment Measurement in Francium

    NASA Astrophysics Data System (ADS)

    Zhang, Jiehang; Sheng, Dong; Orozco, Luis

    2011-05-01

    We present a study of the Polka-Dot microwave plano-spherical mirror for a Fabry-Perot resonator. The microwave resonator is an essential element of the apparatus to measure the anapole moment in francium. A crucial requirement for the cavity is the mode-matching into the fundamental Gaussian TEM00 mode. We investigate new coupling mechanisms of the radiation into the cavity to suppress unwanted higher order modes. We are exploring the method of printing two dimensional array of holes and feeding in through horn antennas. According to a HFSS simulation, this method should improve significantly the mode purity in contrast to conventional antenna. We fabricate the mirrors on standard optical blank using standard film deposition techniques with lithographic method to print the pattern. Preliminary tests show resonances, with potential improvements of the Q factors. Work supported by DOE and NSF

  12. Integral window hermetic fiber optic components

    SciTech Connect

    Dalton, R.D.; Kramer, D.P.; Massey, R.T.; Waker, D.A.

    1994-12-31

    In the fabrication of igniters, actuators, detonators, and other pyrotechnic devices to be activated by a laser beam, an integral optical glass window is formed by placing a preform in the structural member of the device and then melting the glass and sealing it in place by heating at a temperature between the ceramming temperature of the glass and the melting point of the metal, followed by rapid furnace cooling to avoid devitrification. No other sealing material is needed to achieve hermeticity. A preferred embodiment of this type of device is fabricated by allowing the molten glass to flow further and form a plano-convex lens integral with and at the bottom of the window. The lens functions to decrease the beam divergence caused by refraction of the laser light passing through the window when the device is fired by means of a laser beam.

  13. Optical integration of Pancharatnam-Berry phase lens and dynamical phase lens

    NASA Astrophysics Data System (ADS)

    Ke, Yougang; Liu, Yachao; Zhou, Junxiao; Liu, Yuanyuan; Luo, Hailu; Wen, Shuangchun

    2016-03-01

    In the optical system, most elements such as lens, prism, and optical fiber are made of silica glass. Therefore, integrating Pancharatnam-Berry phase elements into silica glass has potential applications in the optical system. In this paper, we take a lens, for example, which integrates a Pancharatnam-Berry phase lens into a conventional plano-convex lens. The spin states and positions of focal points can be modulated by controlling the polarization states of the incident beam. The proposed lens has a high transmission efficiency, and thereby acts as a simple and powerful tool to manipulate spin photons. Furthermore, the method can be conveniently extended to the optical fiber and laser cavity, and may provide a route to the design of the spin-photonic devices.

  14. The construction of a highly transportable laser ranging station

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The technology of the transportable Laser Ranging Station (TLRS) used in crustal dynamics studies was examined. The TLRS used a single photoelectron beam of limited energy density returned from the Laser Geodynamic Satellite (LAGEOS). Calibration was accomplished by the diversion of a small portion of the outgoing beam attenuated to the same level as the satellite return. Timing for the system was based on a self calibrating Ortec TD811, 100 picosec time interval device. The system was contained in a modified, single chassis recreational vehicle that allowed rapid deployment. The TLRS system was only airmobile on the largest transport aircraft. A 30 cm simple plano/concave transfer lens telescope aided in beam direction. The TLRS system fulfills the need for an accurate method of obtaining range measurements to the LAGEOS satellite incorporated in a mobile, air transportable, and economical configuration.

  15. Geomagnetic anomaly detected at hydromagnetic wave frequencies

    NASA Astrophysics Data System (ADS)

    Meloni, A.; Medford, L. V.; Lanzerotti, L. J.

    1985-04-01

    We report the discovery, in northwestern Illinois, of a geomagnetic anomaly, using hydromagnetic wave frequencies as the source spectrum. Three portable magnetometer stations with computer-compatible digital data acquisition systems were operated in a longitude array at Piano and Ashton, Illinois, and Cascade, Iowa (total separation ˜200 km), in 1981-1982. Analysis of the natural geomagnetic field fluctuations in the hydromagnetic wave regime reveals that the vertical components of the detected fluctuations are essentially 180° out of phase between Plano/Ashton and Cascade for variations with periods ˜30-120 s. The observations can be modeled in terms of a shallow (˜10-20 km) north-south oriented geomagnetic anomaly of enhanced conductivity located between Ashton and Cascade, approximately parallel to the Mississippi River valley.

  16. Design and performance of a F/#-conversion microlens for prime focus spectrograph at Subaru Telescope

    NASA Astrophysics Data System (ADS)

    Takato, Naruhisa; Tanaka, Yoko; Gunn, James E.; Tamura, Naoyuki; Shimono, Atsushi; Sugai, Hajime; Karoji, Hiroshi; Ueda, Akitoshi; Waseda, Kouichi; Kimura, Masahiko; Ohyama, Youichi

    2014-07-01

    The PFS is a multi-object spectrograph fed by 2394 fibers at the prime focus of Subaru telescope. Since the F/# at the prime focus is too fast for the spectrograph, we designed a small concave-plano negative lens to be attached to the tip of each fiber that converts the telescope beam (F/2.2) to F/2.8. We optimized the lens to maximize the number of rays that can be confined inside F/2.8 while maintaining a 1.28 magnification. The microlenses are manufactured by glass molding, and an ultra-broadband AR coating (<1.5% for λ = 0.38 - 1.26μm) will be applied to the front surface.

  17. Analysis of laser beam quality degradation caused by quartic phase aberrations.

    PubMed

    Siegman, A E

    1993-10-20

    Simple formulas are derived for the degradation in the beam-quality factor, M(2), of an arbitrary laser beam caused by quartic phase distortions such as those that might occur in a spherically aberrated optical component, a thermally aberrated laser output window, or a divergent beam emerging from a high-index dielectric medium as in a wide-stripe, unstable-resonator diode laser. A new formula for the defocus correction that is needed to collimate optimally a beam with quartic phase aberration is also derived. Analytical results and numerical examples are given for both radially aberrated and one-dimensionaltransversely aberrated cases, and a simple experimental measurement of the beam-quality degradation produced by a thin plano-convex lens is shown to be in good agreement with the theory. PMID:20856411

  18. Generation of Aspherical Optical Lenses via Arrested Spreading and Pinching of a Cross-Linkable Liquid.

    PubMed

    Roy, Abhijit Chandra; Yadav, Mridul; Arul, Edward Peter; Khanna, Anubhav; Ghatak, Animangsu

    2016-05-31

    Aspherical optical lenses with spatially varying curvature are desired for capturing high quality, aberration free images in numerous optical applications. Conventionally such lenses are prepared by multistep top-down processes which are expensive, time-consuming, and prone to high failure rate. In this context, an alternate method is presented here based on arrested spreading of a sessile drop of a transparent, cross-linkable polymeric liquid on a solid substrate heated to an elevated temperature. Whereas surface tension driven flow tends to render it spherical, rapid cross-linking arrests such flow so that nonequilibrium aspherical shapes are attained. It is possible to tune also the initial state of the drop via delayed pinching of a liquid cylinder which precedes its release on the substrate. This method has led to the generation of a wide variety of optical lenses, ranging from spherical plano convex to superspherical solid immersion to exotic lenses not achieved via conventional methods. PMID:27200461

  19. High transmission Ni compound refractive lens for high energy X-rays

    NASA Astrophysics Data System (ADS)

    Brancewicz, M.; Itou, M.; Sakurai, Y.; Andrejczuk, A.; Chiba, S.; Kayahara, Y.; Inoue, T.; Nagamine, M.

    2016-08-01

    We present a new planar Ni compound refractive lens for high energy X-rays (116 keV). The lens is composed of identical plano-concave elements with longitudinal parabolic grooves manufactured by a punch technique. In order to increase the lens transmission, the thickness of the single lens at the parabolic groove vertex was reduced to less than 5 μm and the radius of curvature was reduced to about 20 μm. The small radius of curvature allowed us to reduce the number of single elements needed to get the focal length of 3 m to 54 single lenses. The gain parameter has been significantly improved compared to the previous lenses due to higher transmission, but the focused beam size and its gain are not as good as expected, mostly due to the aberrations caused by the lens shape imperfections.

  20. Directly diode-pumped high-energy Ho:YAG oscillator.

    PubMed

    Lamrini, Samir; Koopmann, Philipp; Schäfer, Michael; Scholle, Karsten; Fuhrberg, Peter

    2012-02-15

    We report on the high-energy laser operation of an Ho:YAG oscillator resonantly pumped by a GaSb-based laser diode stack at 1.9 μm. The output energy was extracted from a compact plano-concave acousto-optically Q-switched resonator optimized for low repetition rates. Operating at 100 Hz, pulse energies exceeding 30 mJ at a wavelength of 2.09 μm were obtained. The corresponding pulse duration at the highest pump power was 100 ns, leading to a maximum peak power above 300 kW. Different pulse repetition rates and output coupling transmissions of the Ho:YAG resonator were studied. In addition, intracavity laser-induced damage threshold measurements are discussed. PMID:22344091

  1. High transmission Ni compound refractive lens for high energy X-rays.

    PubMed

    Brancewicz, M; Itou, M; Sakurai, Y; Andrejczuk, A; Chiba, S; Kayahara, Y; Inoue, T; Nagamine, M

    2016-08-01

    We present a new planar Ni compound refractive lens for high energy X-rays (116 keV). The lens is composed of identical plano-concave elements with longitudinal parabolic grooves manufactured by a punch technique. In order to increase the lens transmission, the thickness of the single lens at the parabolic groove vertex was reduced to less than 5 μm and the radius of curvature was reduced to about 20 μm. The small radius of curvature allowed us to reduce the number of single elements needed to get the focal length of 3 m to 54 single lenses. The gain parameter has been significantly improved compared to the previous lenses due to higher transmission, but the focused beam size and its gain are not as good as expected, mostly due to the aberrations caused by the lens shape imperfections. PMID:27587159

  2. Point Diffraction Interferometry to Measure Local Curvatures and Caustics of Noisy Wave Fronts: Application for Determining Optical Properties of Fish Lenses

    NASA Astrophysics Data System (ADS)

    Vallmitjana, S.; Ricart, I.; Bosch, S.; Gargallo, A.; Acosta, E.

    2015-02-01

    The study of caustics is important because they contain information about the image formation properties of optical systems. In this work we use the concept of caustic as a set of focal points, and we have developed a second order approach theory to determine local slopes and curvatures of a wavefront emerging from an optical system. The method is based on the use of a point diffraction interferometer, and the analysis of the interferograms allows us to compute the focal region. Experimental results obtained with a plano-convex lens demonstrate the accuracy of the combined theoretical-experimental method here developed. Application to noisy wavefronts such as those produced by biological samples, specifically in crystalline lenses of fish eyes, are also exposed.

  3. Foil assisted replica molding for fabrication of microfluidic devices and their application in vitro.

    PubMed

    Micheal, Issac J; Vidyasagar, Aditya J; Bokara, Kiran Kumar; Mekala, Naveen Kumar; Asthana, Amit; Rao, Ch Mohan

    2014-10-01

    We present a simple, rapid, benchtop, Foil Assisted Rapid Molding (FARM) method for the fabrication of microfluidic devices. This novel technique involves the use of aluminium foil, pen and an X-Y plotter to create semi-circular or plano-concave, shallow microchannels. It is an easy do-it-yourself (DIY) technique for creating a microfluidic device in three simple steps: (1) create a channel design using the CAD software, (2) plot the patterns on aluminium foil and (3) use the reverse of the engraved foil as a mold to create microfluidic devices. In this report, we present a detailed study of the proposed method by varying a range of parameters such as foil thickness, tip material, and tip sizes and by investigating their effect on the creation of channels with varying geometry. Furthermore, we demonstrated the cytocompatibility of these devices in vitro. PMID:25102283

  4. [INVITED] Epsilon-near-zero metalenses operating in the visible. Invited paper for the section : Hot topics in Metamaterials and Structures

    NASA Astrophysics Data System (ADS)

    Pacheco-Peña, V.; Navarro-Cía, M.; Beruete, M.

    2016-06-01

    Several converging lenses working in the permittivity near to zero (ENZ) regime at optical frequencies are designed using an array of metal-dielectric-metal plasmonic waveguides. These plasmonic waveguides show a dispersive nature that enable to mimic an effective ENZ medium when using the fast wave transverse electric (TE1) mode near its cut-off wavelength. By arranging multiple plasmonic waveguides with the correct engineered dimensions, several metalenses, including graded index (GRIN) ones, and diffractive optical elements (i.e., zoned metalenses) are proposed. The metalenses are designed at λ0=474.9 nm (f=631.67 THz) with a focal length of 10.75λ0. Numerical results demonstrate that the best performance is obtained for the case of the GRIN metalens in terms of the focal position, transversal resolution and thickness, reducing its volume up to ∼52.3% with respect to the smooth-profiled plano-concave metalens.

  5. Nondestructive millimeter wave imaging and spectroscopy using dielectric focusing probes

    NASA Astrophysics Data System (ADS)

    Hejase, Jose A.; Shane, Steven S.; Park, Kyoung Y.; Chahal, Premjeet

    2014-02-01

    A tool for interrogating objects over a wide band of frequencies with subwavelength resolution at small standoff distances (near field region) in the transmission mode using a single source and detector measurement setup in the millimeter wave band is presented. The design utilizes optics like principles for guiding electromagnetic millimeter waves from large cross-sectional areas to considerably smaller sub-wavelength areas. While plano-convex lenses can be used to focus waves to a fine resolution, they usually require a large stand-off distance thus resulting in alignment and spacing issues. The design procedure and simulation analysis of the focusing probes are presented in this study along with experimental verification of performance and imaging and spectroscopy examples. Nondestructive evaluation will find benefit from such an apparatus including biological tissue imaging, electronic package integrity testing, composite dielectric structure evaluation for defects and microfluidic sensing.

  6. Nondestructive millimeter wave imaging and spectroscopy using dielectric focusing probes

    SciTech Connect

    Hejase, Jose A.; Shane, Steven S.; Park, Kyoung Y.; Chahal, Premjeet

    2014-02-18

    A tool for interrogating objects over a wide band of frequencies with subwavelength resolution at small standoff distances (near field region) in the transmission mode using a single source and detector measurement setup in the millimeter wave band is presented. The design utilizes optics like principles for guiding electromagnetic millimeter waves from large cross-sectional areas to considerably smaller sub-wavelength areas. While plano-convex lenses can be used to focus waves to a fine resolution, they usually require a large stand-off distance thus resulting in alignment and spacing issues. The design procedure and simulation analysis of the focusing probes are presented in this study along with experimental verification of performance and imaging and spectroscopy examples. Nondestructive evaluation will find benefit from such an apparatus including biological tissue imaging, electronic package integrity testing, composite dielectric structure evaluation for defects and microfluidic sensing.

  7. TECHNICAL NOTE: Micro projection lithography using microlens on a mask

    NASA Astrophysics Data System (ADS)

    Ji, Chang-Hyeon; Herrault, Florian; Allen, Mark G.

    2009-12-01

    A micro projection lithography process has been implemented using a photomask having arrays of cylindrical or spherical plano-convex microlenses formed by thermal reflow in proximity exposure mode. This approach provides a practical means to generate patterns inside deep cavities without proximity-based pattern size increases. The generated pattern size can be controlled by controlling the focal depth of the microlens. A maximum pattern size reduction of 62% has been achieved at the bottom of a 216 µm deep trench with a cylindrical microlens having a focal length of 254 µm for a 60 µm square pattern. The effect of the microlens on the lithography process, including the relationship between the focal depth, exposure dose and pattern size, has been analyzed.

  8. Dielectric Optical-Controllable Magnifying Lens by Nonlinear Negative Refraction.

    PubMed

    Cao, Jianjun; Shang, Ce; Zheng, Yuanlin; Feng, Yaming; Chen, Xianfeng; Liang, Xiaogan; Wan, Wenjie

    2015-01-01

    A simple optical lens plays an important role for exploring the microscopic world in science and technology by refracting light with tailored spatially varying refractive indices. Recent advancements in nanotechnology enable novel lenses, such as, superlens and hyperlens, with sub-wavelength resolution capabilities by specially designed materials' refractive indices with meta-materials and transformation optics. However, these artificially nano- or micro-engineered lenses usually suffer high losses from metals and are highly demanding in fabrication. Here, we experimentally demonstrate, for the first time, a nonlinear dielectric magnifying lens using negative refraction by degenerate four-wave mixing in a plano-concave glass slide, obtaining magnified images. Moreover, we transform a nonlinear flat lens into a magnifying lens by introducing transformation optics into the nonlinear regime, achieving an all-optical controllable lensing effect through nonlinear wave mixing, which may have many potential applications in microscopy and imaging science. PMID:26149952

  9. Dielectric Optical-Controllable Magnifying Lens by Nonlinear Negative Refraction

    NASA Astrophysics Data System (ADS)

    Cao, Jianjun; Shang, Ce; Zheng, Yuanlin; Feng, Yaming; Chen, Xianfeng; Liang, Xiaogan; Wan, Wenjie

    2015-07-01

    A simple optical lens plays an important role for exploring the microscopic world in science and technology by refracting light with tailored spatially varying refractive indices. Recent advancements in nanotechnology enable novel lenses, such as, superlens and hyperlens, with sub-wavelength resolution capabilities by specially designed materials’ refractive indices with meta-materials and transformation optics. However, these artificially nano- or micro-engineered lenses usually suffer high losses from metals and are highly demanding in fabrication. Here, we experimentally demonstrate, for the first time, a nonlinear dielectric magnifying lens using negative refraction by degenerate four-wave mixing in a plano-concave glass slide, obtaining magnified images. Moreover, we transform a nonlinear flat lens into a magnifying lens by introducing transformation optics into the nonlinear regime, achieving an all-optical controllable lensing effect through nonlinear wave mixing, which may have many potential applications in microscopy and imaging science.

  10. Spectroscopic and laser characteristics of new YSGG, GSGG, GSAG mixtures doped with Nd 3+

    NASA Astrophysics Data System (ADS)

    Pfistner, C.; Albers, P.; Weber, H. P.; Ostroumov, V. G.; Zharikov, E. V.; Shcherbakov, I. A.; Lutts, G. B.; Zagumenny, A. I.

    1992-04-01

    New mixtures of YSGG, GSGG and GSAG doped with Nd 3+ have been investigated for their spectral and laser properties. Theses hosts allow a higher concentration of Nd 3+ ions than YAG without suffering from concentration queching. The absorption lines for diode pumping in the region of 800 nm are broader than in Nd:YAG. All mixtures have been operated in a quasi plano-concentric resonator end-pumped by a Ti:sapphire laser at 809 nm. With a Nd 3+:YSGG 0.67/GSAG 0.33 crystal we achieved an output power of 580 mW at 1062 nm. With an absorbed pump power of 1.2 W and a threshold of 12 mW this corresponds to a slope efficiency of 48%.

  11. Method of making an integral window hermetic fiber optic component

    DOEpatents

    Dalton, Rick D.; Kramer, Daniel P.; Massey, Richard T.; Waker, Damon A.

    1996-11-12

    In the fabrication of igniters, actuators, detonators, and other pyrotechnic devices to be activated by a laser beam, an integral optical glass window is formed by placing a preform in the structural member of the device and then melting the glass and sealing it in place by heating at a temperature between the ceramming temperature of the glass and the melting point of the metal, followed by rapid furnace cooling to avoid devitrification. No other sealing material is needed to achieve hermeticity. A preferred embodiment of this type of device is fabricated by allowing the molten glass to flow further and form a plano-convex lens integral with and at the bottom of the window. The lens functions to decrease the beam divergence caused by refraction of the laser light passing through the window when the device is fired by means of a laser beam.

  12. Dielectric Optical-Controllable Magnifying Lens by Nonlinear Negative Refraction

    PubMed Central

    Cao, Jianjun; Shang, Ce; Zheng, Yuanlin; Feng, Yaming; Chen, Xianfeng; Liang, Xiaogan; Wan, Wenjie

    2015-01-01

    A simple optical lens plays an important role for exploring the microscopic world in science and technology by refracting light with tailored spatially varying refractive indices. Recent advancements in nanotechnology enable novel lenses, such as, superlens and hyperlens, with sub-wavelength resolution capabilities by specially designed materials’ refractive indices with meta-materials and transformation optics. However, these artificially nano- or micro-engineered lenses usually suffer high losses from metals and are highly demanding in fabrication. Here, we experimentally demonstrate, for the first time, a nonlinear dielectric magnifying lens using negative refraction by degenerate four-wave mixing in a plano-concave glass slide, obtaining magnified images. Moreover, we transform a nonlinear flat lens into a magnifying lens by introducing transformation optics into the nonlinear regime, achieving an all-optical controllable lensing effect through nonlinear wave mixing, which may have many potential applications in microscopy and imaging science. PMID:26149952

  13. Acousto-optic Q-switching laser performance of Yb:GdCa(4)O(BO(3))(3)crystal.

    PubMed

    Chen, Xiaowen; Xu, Honghao; Guo, Yunfeng; Han, Wenjuan; Yu, Haohai; Zhang, Huaijin; Liu, Junhai

    2015-08-20

    We report on the active Q-switching laser performance of Yb:GdCa4O(BO3)3 crystal, demonstrated by employing an acousto-optic Q-switch in a compact plano-concave resonator. Stable repetitively Q-switched operation is achieved with pulse repetition rates varying from 30 to 0.2 kHz, producing an average output power of 10.2 W at 1027.5 nm at 30 kHz of repetition rate, with an optical-to-optical efficiency of 30%. The maximum pulse energy generated at the lowest repetition rate of 0.2 kHz is 4.75 mJ, with a pulse width being 11 ns, gives rise to a peak power that amounts to 432 kW. PMID:26368745

  14. Development of a calibration standard for spherical aberration

    NASA Astrophysics Data System (ADS)

    Compertore, David C.; Ignatovich, Filipp V.; Herbrand, Matthew E.; Marcus, Michael A.

    2013-09-01

    There are no calibration standards currently available for metrology equipment used to measure spherical aberration. We have selected a set of plano-convex lenses that can be used as spherical aberration calibration standards. The key parameters of the lenses were measured using a nodal optical bench and a low coherence interferometer. Spherical aberrations of the lenses were measured using a commercially available aberrometer the CrystalWave™, based on a Shack-Hartmann wavefront sensor. The lenses were then modeled in optical modeling software, where the spherical curvatures of the lenses were adjusted to match the key parameters. The measured spherical aberrations were then compared to the values provided by the modeling software.

  15. Method of making an integral window hermetic fiber optic component

    SciTech Connect

    Dalton, R.D.; Kramer, D.P.; Massey, R.T.; Waker, D.A.

    1996-11-12

    In the fabrication of igniters, actuators, detonators, and other pyrotechnic devices to be activated by a laser beam, an integral optical glass window is formed by placing a preform in the structural member of the device and then melting the glass and sealing it in place by heating at a temperature between the ceramming temperature of the glass and the melting point of the metal, followed by rapid furnace cooling to avoid devitrification. No other sealing material is needed to achieve hermeticity. A preferred embodiment of this type of device is fabricated by allowing the molten glass to flow further and form a plano-convex lens integral with and at the bottom of the window. The lens functions to decrease the beam divergence caused by refraction of the laser light passing through the window when the device is fired by means of a laser beam. 9 figs.

  16. Steps toward 8m honeycomb mirror blanks. III - 1.8m honeycomb sandwich blanks cast from borosilicate glass

    NASA Technical Reports Server (NTRS)

    Angel, J. R. P.; Hill, J. M.

    1984-01-01

    The design, fabrication techniques, and equipment used for producing two 1.8-m honeycomb sandwich blanks, eventually leading to production of 8-m blanks, are reported. The procedure employed 85 cast hexagonal tiles at the bottom section, affixed against flotation by SiC bolts. The two plano concave mirrors are 1.83 m thick, weight 500 kg, and are each designed for 19 supports of astatic-lever type. Both blanks are of high quality and with an adequately low bubble content; one is to be figured to high-precision 0.25-arcsecond images, and is to be tested on the Multiple Mirror Telescope. Construction of a spin-casting facility based on the same principle is being planned for test-fabricating spin-cast mirrors on a smaller scale.

  17. Rapid fabrication of cylindrical microlens array by shaped femtosecond laser direct writing

    NASA Astrophysics Data System (ADS)

    Luo, Zhi; Wang, Cong; Yin, Kai; Dong, Xinran; Chu, Dongkai; Duan, Ji'an

    2016-07-01

    In this study, a remarkable spatial shaping approach is proposed to transform Gaussian femtosecond laser into quasi-Bessel optical field with compressed central lobe and amplified side lobes of the spatial intensity profile. Based on this technique, inward bulge trench (IBT) structures are fabricated with high efficiency on the surface of PMMA by a single illumination step, whose cross-sectional profile is opposite to the results fabricated by Gaussian beam. And plano-convex cylindrical microlens array, which is consistent in size and shape throughout a large sample area, is formed through simply piecing together the IBT structures during fabricating process. Furthermore, numerical simulations of optical field in radial direction and on-axial direction are exploited to rationalize the dependence of the patterned microstructures on the spatial intensity distribution of femtosecond laser.

  18. Reproducible and deterministic production of aspheres

    NASA Astrophysics Data System (ADS)

    Leitz, Ernst Michael; Stroh, Carsten; Schwalb, Fabian

    2015-10-01

    Aspheric lenses are ground in a single point cutting mode. Subsequently different iterative polishing methods are applied followed by aberration measurements on external metrology instruments. For an economical production, metrology and correction steps need to be reduced. More deterministic grinding and polishing is mandatory. Single point grinding is a path-controlled process. The quality of a ground asphere is mainly influenced by the accuracy of the machine. Machine improvements must focus on path accuracy and thermal expansion. Optimized design, materials and thermal management reduce thermal expansion. The path accuracy can be improved using ISO 230-2 standardized measurements. Repeated interferometric measurements over the total travel of all CNC axes in both directions are recorded. Position deviations evaluated in correction tables improve the path accuracy and that of the ground surface. Aspheric polishing using a sub-aperture flexible polishing tool is a dwell time controlled process. For plano and spherical polishing the amount of material removal during polishing is proportional to pressure, relative velocity and time (Preston). For the use of flexible tools on aspheres or freeform surfaces additional non-linear components are necessary. Satisloh ADAPT calculates a predicted removal function from lens geometry, tool geometry and process parameters with FEM. Additionally the tooĺs local removal characteristics is determined in a simple test. By oscillating the tool on a plano or spherical sample of the same lens material, a trench is created. Its 3-D profile is measured to calibrate the removal simulation. Remaining aberrations of the desired lens shape can be predicted, reducing iteration and metrology steps.

  19. Anatomical and functional graft survival, 10 years after epikeratoplasty in keratoconus

    PubMed Central

    Panda, Anita; Gupta, Anoop K; Sharma, Namrata; Nindrakrishna, Sasikala; Vajpayee, Rasik

    2013-01-01

    Purpose: To report outcomes of epikeratoplasty in keratoconus (KC), utilizing manually-prepared plano donor lenticules in terms of flattening of the cone, reduction in astigmatism and improvement in the visual acuity. Materials and Methods: Patients with KC, having visual acuity <20/200, astigmatism >12 diopters (D) but without corneal opacity underwent epikeratoplasty, using manually prepared plano donor lenticules from fresh or M.K preserved corneas, between 1990 - 2000 and followed for 10 years, were included in this report. Visual acuity slit-lamp-biomicroscopy, keratometry, and refraction were performed at 8 weeks, 12 weeks, and 6 months for all 59 patients. The same were carried out at 1 year, 5 years, and 10 years depending upon the availability of the patient for that period. Results: Of the 59 patients, only 26 were available for follow-up after 10 years. At 3 months, 1 year and 5 years, best corrected visual acuity of (BCVA) ≥20/60 were achieved in 84.7%, 84.4% and 80.3% of eyes, respectively. BCVA was 73% at 10-year follow- up, which was due to the presence of posterior subcapsular cataract (PSC). The average keratometric astigmatism and average flattening in diopters stabilized at the end of 3 months, which remained constant at 1, 5, and 10-year follow-up. The average diopter of myopia was stabilized by 1 year, which was almost same at 10 year. Graft was clear in all but 1 eye at 10 year follow-up. Conclusion: Epikeratoplasty is a useful technique for keratoconic eyes without apical scarring who fail or unable to use contact lenses. PMID:23275216

  20. Building achromatic refractive beam shapers

    NASA Astrophysics Data System (ADS)

    Laskin, Alexander; Shealy, David

    2014-10-01

    Achromatic beam shapers can provide beam shaping in a certain spectral band and are very important for various laser techniques, such as, applications based on ultra-short pulse lasers with pulse width <100 fs, confocal microscopy, multicolour holography, life sciences fluorescence techniques, where several lasers in spectrum 405-650 nm are used simultaneously, for example 405-650 nm. Conditions of energy re-distribution and zero wave aberration are strictly fulfilled in ordinary plano-aspheric lens pair beam shapers for a definite wavelength only. Hence, these beam shapers work efficiently in relatively narrow, few nm spectrum. To provide acceptable beam quality for refractive beam shaping over a wide spectrum, an achromatizing design condition should be added. Consequently, the typical beam shaper design contains more than two-lenses, to avoid any damaging and other undesirable effects the lenses of beam shaper should be air-spaced. We suggest a two-step method of designing the beam shaper: 1) achromatizing of each plano-aspheric lens using a buried achromatizing surface ("chromatic radius"), then each beam shaper component presents a cemented doublet lens, 2) "splitting" the cemented lenses and realizing air-spaced lens design using optical systems design software. This method allows for using an achromatic design principle during the first step of the design, and then, refining the design by using optimization software. We shall present examples of this design procedure for an achromatic Keplerian beam shaper and for the design of an achromatic Galilean type of beam shaper. Experimental results of operation of refractive beam shapers will be presented as well.

  1. Estudio fotométrico y espectroscópico de dos cúmulos abiertos jóvenes del disco con apariencia globular

    NASA Astrophysics Data System (ADS)

    Piatti, A. E.; Clariá, J. J.; Bica, E.

    Se presentan y discuten resultados obtenidos en el CASLEO y en el Observatorio de Las Campanas de dos cúmulos abiertos compactos con apariencia globular: Westerlund1 (BH197), ubicado en dirección hacia el centro galáctico, y Westerlund2. A partir de espectroscopía CCD integrada de ambos e imágenes CCD en las bandas VI obtenidas para el primero de ellos, se derivan sus parámetros fundamentales y se examinan sus apariencias estructurales. Se encuentra que Westerlund1 es un cúmulo joven (7 ± 3 millones de años), ubicado sobre el plano galáctico a 1.0 ± 0.4 kpc del sol, en una región caracterizada por una absorción excepcionalmente elevada (Av~=13.0 mag), en tanto que Westerlund2 es también un cúmulo joven (4-6 millones de años) ubicado sobre el plano, en una región afectada por una absorción menor (Av~=5.7 mag). Desde el punto de vista estructural, Westerlund 1 se presenta como uno de los pocos cúmulos abiertos jóvenes de la Galaxia con apariencia tipicamente globular, en contraste con los cúmulos azules de las Nubes de Magallanes en los cuales la apariencia globular constituye un fenómeno común. Westerlund2, aunque menos rico en estrellas, puede también ser incluído dentro de esta interesante clase de objetos.

  2. Managing Fine Sediment in Regulated Rivers

    NASA Astrophysics Data System (ADS)

    Schmidt, J. C.

    2015-12-01

    A paradigm useful in managing dams and diversions is that the combined effects of changing flow regime and sediment supply perturb regulated rivers into sediment deficit or sediment surplus. In the U.S. Southwest, large dams constructed on interregional rivers typically create sediment deficit segments >100 km long. Further downstream, sediment surplus may occur if desert tributaries deliver sufficient amounts of fine sediment, such as parts of the Rio Grande, lower Green River, and Colorado River delta. Sediment surplus also occurs on most smaller regional rivers. The protocols for managing rivers perturbed into sediment deficit have been refined for the Colorado River downstream from Glen Canyon Dam but are nonetheless challenged by externally determined water-supply agreements that require annual water deliveries that sometimes occur when there has been little tributary resupply. Virtually all of the naturally supplied sand to the depleted, 100-km long Marble Canyon comes from the Paria River. The sand delivery rate since 2012 was sufficiently large to trigger short-duration controlled floods under the High Flow Experiment (HFE) Protocol. The sand mass balance of Marble Canyon since 2012 when the HFE Protocol was adopted was positive due to the combination of relatively large sand delivery from the Paria River and average total annual flows. Large total annual flows have the potential to export large amounts of sand and create a negative sand mass balance. Despite the challenge of managing a scarce and highly variable sand supply and occasional years of large reservoir releases, the long-term (2006-2015) sand mass balance for the upstream half of Marble Canyon is indeterminant and is positive for the downstream half of Marble Canyon. The apparent success of managing sand in Grand Canyon under deficit conditions suggests that fine sediment management protocols might be developed for other regulated rivers. Implementation would require establishment of networks of

  3. New vaccine introduction in the East and Southern African sub-region of the WHO African region in the context of GIVS and MDGs.

    PubMed

    Chauke-Moagi, Bafedile E; Mumba, Mutale

    2012-09-01

    Immunization programmes have over the years proven to be effective and useful in infectious disease control. However, based on current trends that show that many developing countries will not reach the Millennium Development Goals (MDG) targets, there is an urgent need to accelerate efforts to control the most common conditions still responsible for the largest morbidity and mortality in children under 5 years of age, like diarrhoea and pneumonia, for which safe and effective vaccines are now available. Through World Health Organization (WHO) and United Nations Children's Fund (UNICEF) strategies and initiatives like the Global Immunization Vision and Strategy (GIVS), Accelerated Disease Control and Reach Every District (RED), major positive achievements like the increasing number of children reached with Diphtheria-Tetanus-Pertussis (DTP) vaccines, significant measles mortality reduction, and the almost complete eradication of polio, have been realised. Many children in developing countries have access to life saving vaccines through the Global Alliance for Vaccines and Immunization (GAVI) support. Supplementary immunization activities against measles and polio continue to offer opportunities to deliver measles and polio vaccines, and other life-saving interventions. The Global Immunization Vision and Strategy 2006-2015 (GIVS framework) can effectively be used to guide countries in addressing some of the remaining challenges to reach the unreached and increase coverage of traditional vaccines, immunize more people against more diseases, support decision making to introduce new vaccines, as well as recognize the opportunity to invest in community health through cost-effective immunization programmes. Introduction of new vaccines should be strengthened and used as vehicles for health systems strengthening as well as for delivery of comprehensive primary health interventions to impact positively on the spiralling disease burden and reduce overall child mortality. A

  4. Quantitative risk assessment of the introduction of rabies into Japan through the illegal landing of dogs from Russian fishing boats in the ports of Hokkaido, Japan.

    PubMed

    Kwan, Nigel C L; Ogawa, Hidehito; Yamada, Akio; Sugiura, Katsuaki

    2016-06-01

    Japan has been free from rabies since 1958 and various preventive measures are in place protecting the country from the introduction of the disease. Historical reviews indicate that the illegal landing of dogs from Russian fishing boats in the ports of Hokkaido occurred frequently especially in the early 2000s and this could potentially be a source of introduction of rabies into Japan. The method of scenario tree modelling was used and the following entry and exposure pathway was considered the most likely route of rabies entry: a rabies-infected dog arriving on a Russian fishing boat lands in a port of Hokkaido in Japan, it becomes infectious, contacts and infects a susceptible domestic animal (companion dog, stray dog or wildlife). Input parameter values were based on surveys of Russian fishermen, expert opinion and scientific data from the literature. At present (2006-2015), the probability of the introduction of rabies as a result of one Russian fishing boat arriving at a port of Hokkaido is 8.33×10(-10) (90% Prediction Interval (PI): 7.15×10(-11)-5.34×10(-9)), while this probability would have been 7.70×10(-9) (90% PI: 6.40×10(-10)-4.81×10(-8)) in the past (1998-2005). Under the current situation (average annual number of boat arrivals is 1106), rabies would enter Japan every 1,084,849 (90% PI: 169,215-20,188,348) years, while the disease would have been introduced every 18,309 (90% PI: 2929-220,048) years in the past (average annual number of boat arrivals is 7092). The risk of rabies introduction has decreased 59 fold due to both the effective control of the issue of illegal landing of dogs and the decline in the number of Russian boat arrivals. Control efforts include education of Russian fishermen, establishment of warning signs, daily patrols and regular port surveillance of potential dog landing activity. Furthermore, scenario analysis revealed that the policy of mandatory domestic dog vaccination does not contribute effectively to Japan's rabies

  5. Polish up on past pestilence and present pathogens.

    PubMed

    Schofield, Cynthia B

    2008-06-01

    The cases presented here illustrate potential epidemic or pandemic events that once-silent pathogens portend. Developing countries, where defenses are limited, are primary targets. Of future concern are the developed countries that fail to use rigorous control measures established by the CDC, the WHO, and others to prevent the spread of infectious diseases. International travel has brought changes in demographics and a greater need for surveillance programs to control selective antibiotic resistance. In our first case, the patient's death would likely have been avoided if he had adhered to the CDC-recommended vaccine program. The fact remains that 20% to 60% of U.S. adults, including travelers to endemic areas, have not followed the diphtheria booster-vaccine schedule. Our second case demonstrates the ease of transmission through food and water that contribute to illness from cholera. The success of intravenous therapy or ORS treatment has reduced the number of deaths by approximately 3 million per year in Asia and Africa. Though development of oral vaccines may be promising, without water and sewage control, waterborne transmission of cholera is a continuing threat. The panic following our third case was a sample of the pandemonium an outbreak of XDR-TB would create. Lack of access to medical care and lack of funding in developing countries made selection of resistance from MDR- to XDR-TB a predictable event. The Global Plan to Stop TB 2006-2015, initiated to improve on the DOTS strategy to control TB/HIV and MDR-TB cases, targets 2015 for reducing overall prevalence and mortality from TB. Based on the principle that community healthcare is the best prevention, organizations that are dedicated to the control of emerging and re-emerging infection include the CDC, NIH, IDSA, ATS, and the National Academy of Science's Institute of Medicine, to mention a few. Recently, they have established plans and programs to address problems of communication among scientists and

  6. On the reduced sensitivity of the Atlantic overturning to Greenland ice sheet melting in projections: a multi-model assessment

    NASA Astrophysics Data System (ADS)

    Swingedouw, Didier; Rodehacke, Christian B.; Olsen, Steffen M.; Menary, Matthew; Gao, Yongqi; Mikolajewicz, Uwe; Mignot, Juliette

    2014-08-01

    Large uncertainties exist concerning the impact of Greenland ice sheet melting on the Atlantic meridional overturning circulation (AMOC) in the future, partly due to different sensitivity of the AMOC to freshwater input in the North Atlantic among climate models. Here we analyse five projections from different coupled ocean-atmosphere models with an additional 0.1 Sv (1 Sv = 106 m3/s) of freshwater released around Greenland between 2050 and 2089. We find on average a further weakening of the AMOC at 26°N of 1.1 ± 0.6 Sv representing a 27 ± 14 % supplementary weakening in 2080-2089, as compared to the weakening relative to 2006-2015 due to the effect of the external forcing only. This weakening is lower than what has been found with the same ensemble of models in an identical experimental set-up but under recent historical climate conditions. This lower sensitivity in a warmer world is explained by two main factors. First, a tendency of decoupling is detected between the surface and the deep ocean caused by an increased thermal stratification in the North Atlantic under the effect of global warming. This induces a shoaling of ocean deep ventilation through convection hence ventilating only intermediate levels. The second important effect concerns the so-called Canary Current freshwater leakage; a process by which additionally released freshwater in the North Atlantic leaks along the Canary Current and escapes the convection zones towards the subtropical area. This leakage is increasing in a warming climate, which is a consequence of decreasing gyres asymmetry due to changes in Ekman pumping. We suggest that these modifications are related with the northward shift of the jet stream in a warmer world. For these two reasons the AMOC is less susceptible to freshwater perturbations (near the deep water formation sides) in the North Atlantic as compared to the recent historical climate conditions. Finally, we propose a bilinear model that accounts for the two former

  7. The role of turbulence in the cycling of persistent organic pollutants in the North Sea

    NASA Astrophysics Data System (ADS)

    O'Driscoll, Kieran

    2014-05-01

    and distributions in sediment. Pre-storm sediment POP concentrations may or may not be recovered in the time period following the storm, which depends on a number of factors including the hydrophobicity of the substance, the amount already contained in the system and the amount of it entering the system. Results from a ten year present day run (1996-2005) and three ten year scenario runs (2006-2015, 2046-2055, 2090-2099) are presented. Distributions of near-bottom turbulent diffusivity coefficients and POP distributions are presented and discussed, as are the effects of the turbulence on the different POP model processes.

  8. Climate variabilty in Northeast Brazil lakes since the LGM

    NASA Astrophysics Data System (ADS)

    Turcq, B.; Albuquerque, A.; Cordeiro, R. C.; Costa, R. L.; Sifeddine, A.; Zocatelli, R.

    2012-12-01

    The Late Glacial and Holocene climate evolution in Northeast Brazil is from different the rest of South America. We present here the results from two Northeast lakes: Caço and Boqueirão, both situated some tens of kilometers from the Atlantic coast. Although there is some indications of wetness during the LGM from stalagmite formation, the Caço lake, which is the only one where late glacial sediments have been sampled, was dry until 17 kyrs when sandy layers were deposited by flash floods. The lake developed during H1 and lake-level peaked from 16 to 12 kyrs. It has been shown that Heinrich events provoked a southward shift of ITCZ which should have enhanced rainfalls in Northeast Brazil. During the Holocene, what dominated the millenary climate trend is the change in insolation, due to the precession of equinoxes, which was increased (decreased) from January to February (June to August) from 12 to 9 kyrs. This forcing difference has been reduced progressively until now with a faster decrease around 5-4 kyrs. The insolation diminution in Austral summer provoked a drop of South American Monsoon, and associated rainfalls, which is marked in Southeast Brazil and Amazonia by savannah development and lake drying. In Northeast Brazil, on the contrary, Early to Middle Holocene climate (12 to 4 kyrs) is markedly wetter. Climate simulations by AOGCM indicate that it is due to a more southern position of ITCZ during austral summers. Analysis with IPSL AOGCM show that this situation lasted until at least 4 kyrs. The two lakes have almost completely dried around 3 kyrs for lake Caço and 1550 AD for Boqueirão. This is in agreement with what we know of Holocene paleoclimate and the diminishing presence of ITCZ in the region. What is surprising is the reappearance of both lakes, very recently, probably during the last 100 yrs. Another striking feature is the great decenal to centennial variability of lake-level observed between 3 and 2 kyrs at lake Boqueirão. Lake Caço was

  9. Solution rheology of polyelectrolytes and polyelectrolyte-surfactant systems

    NASA Astrophysics Data System (ADS)

    Plucktaveesak, Nopparat

    (styrene-alt-sodium maleate) and poly(diisobutylene- alt-sodium maleate) show the polyelectrolyte behavior as predicted. However, the viscosity as a function of concentration of sodium maleate based copolymers with 1-alkenes; 1-octene (C8), 1-decene (C10), 1-dodecene (C12) and 1-hexene (C14) exhibit an abnormal scaling power, which might be caused by aggregation of the alkene tails to form micelles. In the last chapter, we report the rheological properties of aqueous solutions of poly(acrylic acid) and oppositely charged surfactant, dodecyl trimethylammonium bromide (C12TAB). The solution viscosity decreases as surfactant is added, partly because the polyelectrolyte wraps around the surface of the spherical surfactant micelles, shortening the effective chain length. The effects of polymer molecular weight, polymer concentration, and polymer charge have been studied with no added salt. The results are compared with the predictions of a simple model based on the scaling theory for the viscosity of dilute and unentangled semidilute polyelectrolyte solutions in good solvent. This model takes into account two effects of added surfactant. The effective chain length of the polyelectrolyte is shortened when a significant fraction of the chain wraps around micelles. Another effect is the change of solution ionic strength resulting from surfactant addition that further lowers the viscosity. The parameters used in this model are independently determined, allowing the model to make a quantitative prediction of solution viscosity with no adjustable parameters. The model is also applied to predict the decrease in viscosity of various polyelectrolyte/oppositely charged surfactant systems reported in literature. The results are in good agreement with experimental data, proving that our model applies to all polyelectrolytes mixed with oppositely charged surfactants that form spherical micelles.

  10. Orthographic Projection Capillary Array Fluorescent Sensor for mHealth

    PubMed Central

    Balsam, Joshua; Bruck, Hugh Alan; Rasooly, Avraham

    2013-01-01

    To overcome the limited sensitivity of phone cameras for mobile health (mHealth) fluorescent detection, we have previously developed a capillary array which enables a ~100× increase in detection sensitivity. However, for an effective detection platform, the optical configuration must allow for uniform measurement sensitivity between channels when using such a capillary array sensor. This is a challenge due to the parallax inherent in imaging long parallel capillary tubes with typical lens configurations. To enable effective detection, we have developed an orthographic projection system in this work which forms parallel light projection images from the capillaries using an object-space telecentric lens configuration. This optical configuration results in a significantly higher degree of uniformity in measurement between channels, as well as a significantly reduced focal distance, which enables a more compact sensor. A plano-convex lens (f = 150 mm) was shown to produce a uniform orthographic projection when properly combined with the phone camera’s built in lens (f = 4 mm), enabling measurements of long capillaries (125 mm) to be made from a distance of 160 mm. The number of parallel measurements which can be made is determined by the size of the secondary lens. Based on these results, a more compact configuration with shorter 32 mm capillaries and a plano-convex lens with a shorter focal length (f = 10 mm) was constructed. This optical system was used to measure serial dilutions of fluorescein with a limit of detection (LOD) of 10 nM, similar to the LOD of a commercial plate reader. However, many plate readers based on standard 96 well plate requires sample volumes of 100 ul for measurement, while the capillary array requires a sample volume of less than 10 ul. This optical configuration allows for a device to make use of the ~100× increase in fluorescent detection sensitivity produced by capillary amplification while maintaining a compact size and capability

  11. Controle orbital de satélites artificiais com propulsão e uso de gravidade lunar

    NASA Astrophysics Data System (ADS)

    Torres, K. S.; de Almeida Prado, A. F. B.

    2003-08-01

    A redução do custo de combustível de uma manobra é atualmente a grande prioridade de todos os programas espaciais existentes no mundo. As manobras assistidas pela gravidade são uma ótima forma de se contornar o problema pois proporcionam economias com vasto impacto no custo final da missão. Neste trabalho é feito um estudo particular do controle orbital de um satélite artificial da Terra usando a gravidade da Lua. O objetivo é estudar uma técnica econômica para uma mudança de plano de um satélite que está em órbita em volta da Terra. A idéia principal desta abordagem é enviar primeiramente o veículo espacial em direção à Lua usando uma manobra mono-impulsiva para que assim o campo gravitacional da Lua possa fazer a mudança de plano desejada (sem custo de combustível) e só então retornar o veículo aos valores iniciais de semi-eixo e excentricidade usando uma manobra bi-impulsiva tipo Hohmann. Para tanto, é assumido que a espaçonave inicia em uma órbita circular coplanar à órbita da lua em torno da Terra e a meta é colocá-la em uma órbita similar que difere da órbita inicial somente pela inclinação. São usadas equações analíticas baseadas na abordagem Patched Conics para se calcular a variação na velocidade, momento angular, energia e inclinação do veículo espacial que realiza esta manobra. Várias simulações são feitas para se avaliar as economias de combustível envolvidas.

  12. Comparison of nanoparticle-mediated transfection methods for DNA expression plasmids: efficiency and cytotoxicity

    PubMed Central

    2011-01-01

    Background Reproducibly high transfection rates with low methodology-induced cytotoxic side effects are essential to attain the required effect on targeted cells when exogenous DNA is transfected. Different approaches and modifications such as the use of nanoparticles (NPs) are being evaluated to increase transfection efficiencies. Several studies have focused on the attained transfection efficiency after NP-mediated approaches. However, data comparing toxicity of these novel approaches with conventional methods is still rare. Transfection efficiency and methodology-induced cytotoxicity were analysed after transfection with different NP-mediated and conventional approaches. Two eukaryotic DNA-expression-plasmids were used to transfect the mammalian cell line MTH53A applying six different transfection protocols: conventional transfection reagent (FuGENE HD, FHD), FHD in combination with two different sizes of stabilizer-free laser-generated AuNPs (PLAL-AuNPs_S1,_S2), FHD and commercially available AuNPs (Plano-AuNP), and two magnetic transfection protocols. 24 h post transfection efficiency of each protocol was analysed using fluorescence microscopy and GFP-based flow cytometry. Toxicity was assessed measuring cell proliferation and percentage of propidium iodide (PI%) positive cells. Expression of the respective recombinant proteins was evaluated by immunofluorescence. Results The addition of AuNPs to the transfection protocols significantly increased transfection efficiency in the pIRES-hrGFPII-eIL-12 transfections (FHD: 16%; AuNPs mean: 28%), whereas the magnet-assisted protocols did not increase efficiency. Ligand-free PLAL-AuNPs had no significant cytotoxic effect, while the ligand-stabilized Plano-AuNPs induced a significant increase in the PI% and lower cell proliferation. For pIRES-hrGFPII-rHMGB1 transfections significantly higher transfection efficiency was observed with PLAL-AuNPs (FHD: 31%; PLAL-AuNPs_S1: 46%; PLAL-AuNPs_S2: 50%), while the magnet

  13. Ancient lenses in art and sculpture and the objects viewed through them, dating back 4500 years

    NASA Astrophysics Data System (ADS)

    Enoch, Jay M.

    1998-07-01

    The early history of lenses is controversial. The author has sought to address the problem by identifying lens elements (mainly convex/plano) which remain associated with objects intended to be viewed through them (i.e., in their original context). These are found in museums in sculptures, rings, pendants, etc. A number of outstanding examples will be illustrated in the talk; these sophisticated pieces of art are certainly not first constructs. Most are of rock crystal, rose quartz, or glass. Lenses have origin among artisans rather than scientists. Clearly, skills were often lost and rediscovered. Early lens-like objects have been found broadly in the eastern Mediterranean area/Middle East, in France, in Italy (Rome), and possibly in Peru and Scandinavia, etc. To date, the earliest lenses identified in context are from the IV/V Dynasties of Egypt, dating back to about 4500 years ago (e.g., the superb `Le Scribe Accroupi' and `the Kai' in the Louvre; added fine examples are located in the Cairo Museum). Latter examples have been found in Knossos (Minoan [Herakleion Museum]; ca. 3500 years ago); others had origin in Greece (examples in the Athens National Archeological Museum and the British Museum equals BM), in Rome (Metropolitan Museum, NY; BM; Vatican Museums; Bologna Archeological Museum), etc. Also. of great interest is the study of possible lens applications. This is a fascinating scientific, artistic and intellectual project.

  14. Tunable, diode side-pumped Er:YAG laser

    DOEpatents

    Hamilton, C.E.; Furu, L.H.

    1997-04-22

    A discrete-element Er:YAG laser, side pumped by a 220 Watt peak-power InGaAs diode array, generates >500 mWatts at 2.94 {micro}m, and is tunable over a 6 nm range near about 2.936 {micro}m. The oscillator is a plano-concave resonator consisting of a concave high reflector, a flat output coupler, a Er:YAG crystal and a YAG intracavity etalon, which serves as the tuning element. The cavity length is variable from 3 cm to 4 cm. The oscillator uses total internal reflection in the Er:YAG crystal to allow efficient coupling of the diode emission into the resonating modes of the oscillator. With the tuning element removed, the oscillator produces up to 1.3 Watts of average power at 2.94 {micro}m. The duty factor of the laser is 6.5% and the repetition rate is variable up to 1 kHz. This laser is useful for tuning to an atmospheric transmission window at 2.935 {micro}m (air wavelength). The laser is also useful as a spectroscopic tool because it can access several infrared water vapor transitions, as well as transitions in organic compounds. Other uses include medical applications (e.g., for tissue ablation and uses with fiber optic laser scalpels) and as part of industrial effluent monitoring systems. 4 figs.

  15. Calculation of coherent emissions and gain from a prebunched Free Electron Laser

    SciTech Connect

    Treadwell, E.A. |

    1995-08-01

    This report advances a theoretical model for the single pass growth of coherent radiation in a prebunched FEL system. The FEL system includes a radio frequency linear accelerator (fr linac) as the injector, a resonator cavity with a wiggler magnet, and two highly reflective plano-concave mirrors, typically 99{percent} of the radiation is reflected inside the resonator. The model is based upon the following assumptions: a) the electron beam is cold, b) a super- electron is a particle with {approximately} 10{sup 8} elementary charges inside a bunch; the bunch length is much smaller than the radiation wavelength and the super-electron scatters with the rf wave in a single pass through the resonator, c) a smooth phase space transition must exist between the rf linac and the resonator, d) the energy gain is low per pass and consequently in the linear gain regime, and e) if condition (b) is satisfied and the bunch is resonant with the FEL beat wave, all electrons lose energy to the wave, in the lowest order approximation. A simple scaling technique is used to calculate the output power given the number of particles in a bunch and the efficiency for retrieving coherent radiation from the resonator. 4 refs., 8 figs., 2 tabs.

  16. Timing performance of the Thorn EMI 9127 and 9128 photomultipliers

    NASA Astrophysics Data System (ADS)

    Hobson, P.; Price, T.

    1992-06-01

    Three recently designed Thorn EMI photomultipliers (9127, 9128 and D192) have been evaluated in this work. They are all 28 mm in diameter, 11-stage devices. The 9127 has a flat photocathode and the 9128 and D192 have plano-concave windows to minimise the variation in distance between any point on the photocathode and the first dynode. In addition the D192 has a RbTe photocathode which makes it sensitive only to UV wavelengths in the range from 190 to 280 nm. The best single counter timing resolutions, uncorrected for pulse height effects, obtained were 150, 160 and 220 ps for the 9127, 9128 and D192 respectively for detection of coincident 511 keV photons. Correcting for the time walk of the constant fraction discriminators, we achieved a counter resolution of 120 ps with the 9128. The electron transit time variation across the photocathode was measured and used to explain the relative timing performance of the tubes with different dynode chains and scintillator geometries. The leading edge jitter of the output pulse has been measured in an independent way using a mode locked picosecond-pulse dye laser to be 125 ps.

  17. The role of affordances in children's learning performance and efficiency when using virtual manipulative mathematics touch-screen apps

    NASA Astrophysics Data System (ADS)

    Moyer-Packenham, Patricia S.; Bullock, Emma K.; Shumway, Jessica F.; Tucker, Stephen I.; Watts, Christina M.; Westenskow, Arla; Anderson-Pence, Katie L.; Maahs-Fladung, Cathy; Boyer-Thurgood, Jennifer; Gulkilik, Hilal; Jordan, Kerry

    2016-03-01

    This paper focuses on understanding the role that affordances played in children's learning performance and efficiency during clinical interviews of their interactions with mathematics apps on touch-screen devices. One hundred children, ages 3 to 8, each used six different virtual manipulative mathematics apps during 30-40-min interviews. The study used a convergent mixed methods design, in which quantitative and qualitative data were collected concurrently to answer the research questions (Creswell and Plano Clark 2011). Videos were used to capture each child's interactions with the virtual manipulative mathematics apps, document learning performance and efficiency, and record children's interactions with the affordances within the apps. Quantitized video data answered the research question on differences in children's learning performance and efficiency between pre- and post-assessments. A Wilcoxon matched pairs signed-rank test was used to explore these data. Qualitative video data was used to identify affordance access by children when using each app, identifying 95 potential helping and hindering affordances among the 18 apps. The results showed that there were changes in children's learning performance and efficiency when children accessed a helping or a hindering affordance. Helping affordances were more likely to be accessed by children who progressed between the pre- and post-assessments, and the same affordances had helping and hindering effects for different children. These results have important implications for the design of virtual manipulative mathematics learning apps.

  18. Ion beam figuring system in NUDT

    NASA Astrophysics Data System (ADS)

    Zhou, Lin; Xie, Xuhui; Dai, Yifan; Jiao, Changjun; Li, Shengyi

    2007-12-01

    Ion beam figuring (IBF) is an optical fabrication technique that provides highly deterministic process to correct surface figure error of previously polished surfaces by using a directed, inert and neutralized ion beam to physically sputter material from the optic surface. Recently, an ion beam figuring system KDIFS-500 has been designed and built in National University of Defense Technology (NUDT) of the P.R. China. KDIFS-500 is capable of processing workpiece up to Φ500mm. Line scanning process was discussed in detail for estimating the parameters of the beam removal function (BRF) in process. Experiments were conducted to demonstrate that the BRF increases gradually in process and by employing a stability control, the BRF can be kept stable in process. Finally, a Φ95 mm plano optical sample of CVD coated SiC substrate has been figured in two process iterations for demonstrating the correction capability of the KDIFS-500. Their figure convergence ratios reached 5.8 and 2.1 respectively. The actual figure residual errors were basically consistent with the predicted error. These consistencies indicated that the IBF processes on KDIFS-500 are predictable deterministic processes.

  19. Optical cavity integrated surface ion trap for enhanced light collection

    NASA Astrophysics Data System (ADS)

    Benito, Francisco M.

    Ion trap systems allow the faithful storage and manipulation of qubits encoded in the energy levels of the ions, and can be interfaced with photonic qubits that can be transmitted to connect remote quantum systems. Single photons transmitted from two remote sites, each entangled with one quantum memory, can be used to entangle distant quantum memories by interfering on a beam splitter. Efficient remote entanglement generation relies upon efficient light collection from single ions into a single mode fiber. This can be realized by integrating an ion trap with an optical cavity and employing the Purcell effect for enhancing the light collection. Remote entanglement can be used as a resource for a quantum repeater for provably secure long-distance communication or as a method for communicating within a distributed quantum information processor. We present the integration of a 1 mm optical cavity with a micro-fabricated surface ion trap. The plano-concave cavity is oriented normal to the chip surface where the planar mirror is attached underneath the trap chip. The cavity is locked using a 780 nm laser which is stabilized to Rubidium and shifted to match the 369 nm Doppler transition in Ytterbium. The linear ion trap allows ions to be shuttled in and out of the cavity mode. The Purcell enhancement of spontaneous emission into the cavity mode would then allow efficient collection of the emitted photons, enabling faster remote entanglement generation.

  20. Measurement of xenon plasma properties in an ion thruster using laser Thomson scattering technique

    SciTech Connect

    Yamamoto, N.; Tomita, K.; Sugita, K.; Kurita, T.; Nakashima, H.; Uchino, K.

    2012-07-15

    This paper reports on the development of a method for measuring xenon plasma properties using the laser Thomson scattering technique, for application to ion engine system design. The thresholds of photo-ionization of xenon plasma were investigated and the number density of metastable atoms, which are photo-ionized by a probe laser, was measured using laser absorption spectroscopy, for several conditions. The measured threshold energy of the probe laser using a plano-convex lens with a focal length of 200 mm was 150 mJ for a xenon mass flow rate of 20 {mu}g/s and incident microwave power of 6 W; the probe laser energy was therefore set as 80 mJ. Electron number density was found to be (6.2 {+-} 0.4) Multiplication-Sign 10{sup 17} m{sup -3} and electron temperature was found to be 2.2 {+-} 0.4 eV at a xenon mass flow rate of 20 {mu}g/s and incident microwave power of 6 W. The threshold of the probe laser intensity against photo-ionization in a miniature xenon ion thruster is almost constant for various mass flow rates, since the ratio of population of the metastable atoms to the electron number density is little changed.

  1. The oceanic segment of the southern Brazilian margin: Morpho-structural domains and their tectonic significance

    NASA Astrophysics Data System (ADS)

    Bassetto, Marcelo; Alkmim, Fernando F.; Szatmari, Peter; Mohriak, Webster U.

    A descriptive and evolutionary analysis of the main morpho-structural features of the oceanic domain of the southern portion of the Brazilian Continental Margin is supported by regional seismic profiles and potential field data from the Brazilian governmental LEPLAC (Plano de Levantamento da Plataforma Continental Brasileira) Project. The several morpho-structural elements can be differentiated, as for example: the dominant structural pattern of the acoustic basement, including extensional faulting and long-wavelength folding, crustal thickness changes, fracture zones location, distribution of volcanic centers, and development of wedges of seaward-dipping reflectors. Four broad distinct morpho-structural domains, separated by fracture zones and oceanic lineaments. Domain I is located south of the Porto Alegre Lineament; Domain II corresponds to the area between the Porto Alegre Lineament and the Rio Grande Fracture Zone; Domain III spans the area of the São Paulo Plateau; and Domain IV is located to the east of this plateau, towards the abyssal portions of the oceanic crust. These domains are defined by their distinct regional morphologic and structural characteristics. Sometimes these elements are well imaged in the seismic profiles, corroborated by gravity and magnetic anomalies, and eventually identified as prominent features at the sea bottom physiography. Using a multidisciplinary approach based on bathymetric maps, regional seismic interpretation, magnetic data analysis, and gravity models, this work attempts to characterize these elements in a descriptive and evolutionary view, identifying their role in the tectonic development of this portion of the South Atlantic.

  2. Measurement of xenon plasma properties in an ion thruster using laser Thomson scattering technique.

    PubMed

    Yamamoto, N; Tomita, K; Sugita, K; Kurita, T; Nakashima, H; Uchino, K

    2012-07-01

    This paper reports on the development of a method for measuring xenon plasma properties using the laser Thomson scattering technique, for application to ion engine system design. The thresholds of photo-ionization of xenon plasma were investigated and the number density of metastable atoms, which are photo-ionized by a probe laser, was measured using laser absorption spectroscopy, for several conditions. The measured threshold energy of the probe laser using a plano-convex lens with a focal length of 200 mm was 150 mJ for a xenon mass flow rate of 20 μg/s and incident microwave power of 6 W; the probe laser energy was therefore set as 80 mJ. Electron number density was found to be (6.2 ± 0.4) × 10(17) m(-3) and electron temperature was found to be 2.2 ± 0.4 eV at a xenon mass flow rate of 20 μg/s and incident microwave power of 6 W. The threshold of the probe laser intensity against photo-ionization in a miniature xenon ion thruster is almost constant for various mass flow rates, since the ratio of population of the metastable atoms to the electron number density is little changed. PMID:22852670

  3. Efficient passive Q-switching operation of a diode-pumped Nd:GdVO4 laser with a Cr4+:YAG saturable absorber

    NASA Astrophysics Data System (ADS)

    Liu, Junhai; Ozygus, Bernd; Yang, Suhui; Erhard, Jürgen; Seelig, Ute; Ding, Adalbert; Weber, Horst; Meng, Xianlin; Zhu, Li; Qin, Lianjie; Du, Chenlin; Xu, Xinguang; Shao, Zongshu

    2003-04-01

    A diode-pumped highly efficient Cr4+:YAG passively Q-switched Nd:GdVO4 laser formed by a plano-concave resonator has been demonstrated. At the highest attainable absorbed pump power of 11.4 W, 4.05 W of average output power, which was two thirds of the maximum corresponding cw output, was achieved with an optical conversion efficiency of 35.5%, and the slope efficiency was determined to be 46.8%, reaching 85% of the magnitude of its cw counterpart. The resulting shortest pulse duration, single-pulse energy, and peak power were found to be 13 ns, 90 μJ, and 7 kW, respectively, with a pulse repetition frequency (PRF) of 45 kHz. Two particularly modified resonator configurations were employed; the largest pulse energy and the highest peak power reached were, respectively, 154 μJ and 11.2 kW at 8.5 W of absorbed pump power. An analytical relation between the PRF and the absorbed pump power is given for a passively Q-switched laser, showing good consistency with experiment with a Nd:GdVO4 laser. The dependence of the operational parameters on the pump power and on the output coupling was also investigated experimentally. Issues involving the criterion for passive Q switching are discussed in some detail for Cr4+:YAG passively Q-switched neodymium-doped vanadate lasers.

  4. Design and fabrication of a 3m class light weighted mirror blank for the E-ELT M5

    NASA Astrophysics Data System (ADS)

    Jedamzik, Ralf; Seibert, Volker; Thomas, Armin; Westerhoff, Thomas; Müller, Michael; Cayrel, Marc

    2011-09-01

    In the recent past, SCHOTT has demonstrated its ability to manufacture large light weighted ZERODUR® mirror blanks for telescope projects like the GREGOR solar-telescope, for example. In 2010, SCHOTT was commissioned with a study aimed at developing a design for the M5 mirror blank of the ESO E-ELT. The tip and tilt M5 mirror of the European Extremely Large Telescope (E-ELT) requires a demanding approach in light weighting. The approximately 3.1 m x 2.5 m elliptical plano mirror is specified to a weight of less than 500 kg with high Eigenfrequencies and low deformation under different inclination angles. The study was divided into two parts. The first part focused on coming up with an optimized light weighted design with respect to performance and processability with finite element modeling. In the second part of the study, a concept for the processing sequence including melting, cold-processing, acid etching and handling of the M5 blank was developed. By producing a prototype section, SCHOTT demonstrated its ability to manufacture the demanding features, including pockets 350 mm in depth, thin walls and sloped pocket bottoms. This paper outlines the results of the design work, processing concept and demonstrator fabrication.

  5. Development of ion beam figuring system with electrostatic deflection for ultraprecise X-ray reflective optics

    SciTech Connect

    Yamada, Jumpei; Matsuyama, Satoshi Sano, Yasuhisa; Yamauchi, Kazuto

    2015-09-15

    We developed an ion beam figuring system that utilizes electrostatic deflection. The system can produce an arbitrary shape by deterministically scanning the ion beam. The scan of the ion beam, which can be precisely controlled using only an electrical signal, enables us to avoid degradation of the mirror shape caused by imperfect acceleration or deceleration of a mechanically scanning stage. Additionally, this surface figuring method can easily be combined with X-ray metrology because the workpiece remains fixed during the figuring. We evaluated the figuring accuracy of the system by fabricating a plano-elliptical mirror for X-ray focusing. A mirror with a shape error of 1.4 nm root mean square (RMS) with a maximum removal depth of 992 nm, which corresponds to figuring accuracy of 0.14% RMS, was achieved. After the second shape corrections, an elliptical shape with a shape error of approximately 1 nm peak-to-valley, 0.48 nm RMS could be fabricated. Then, the mirror surface was smoothed by a low-energy ion beam. Consequently, a micro-roughness of 0.117 nm RMS, measured by atomic force microscopy, was achieved over an area of 1 × 1 μm{sup 2}.

  6. Cognitive fusion analysis based on context

    NASA Astrophysics Data System (ADS)

    Blasch, Erik P.; Plano, Susan

    2004-04-01

    The standard fusion model includes active and passive user interaction in level 5 - "User Refinement". User refinement is more than just details of passive automation partitioning - it is the active management of information. While a fusion system can explore many operational conditions over myopic changes, the user has the ability to reason about the hyperopic "big picture." Blasch and Plano developed cognitive-fusion models that address user constraints including: intent, attention, trust, workload, and throughput to facilitate hyperopic analysis. To enhance user-fusion performance modeling (i.e. confidence, timeliness, and accuracy); we seek to explore the nature of context. Context, the interrelated conditions of which something exists, can be modeled in many ways including geographic, sensor, object, and environmental conditioning. This paper highlights user refinement actions based on context to constrain the fusion analysis for accurately representing the trade space in the real world. As an example, we explore a target identification task in which contextual information from the user"s cognitive model is imparted to a fusion belief filter.

  7. Intricate Plasma-Scattered Images and Spectra of Focused Femtosecond Laser Pulses.

    PubMed

    Ooi, C H Raymond; Talib, Md Ridzuan

    2016-01-01

    We report on some interesting phenomena in the focusing and scattering of femtosecond laser pulses in free space that provide insights on intense laser plasma interactions. The scattered image in the far field is analyzed and the connection with the observed structure of the plasma at the focus is discussed. We explain the physical mechanisms behind the changes in the colorful and intricate image formed by scattering from the plasma for different compressions, as well as orientations of plano-convex lens. The laser power does not show significant effect on the images. The pulse repetition rate above 500 Hz can affect the image through slow dynamics The spectrum of each color in the image shows oscillatory peaks due to interference of delayed pulse that correlate with the plasma length. Spectral lines of atomic species are identified and new peaks are observed through the white light emitted by the plasma spot. We find that an Ar gas jet can brighten the white light of the plasma spot and produce high resolution spectral peaks. The intricate image is found to be extremely sensitive and this is useful for applications in sensing microscale objects. PMID:27571644

  8. Design and analysis of range finder for medium distance

    NASA Astrophysics Data System (ADS)

    Wang, Hongjun; Hui, Lei

    2015-02-01

    This paper introduces the research and design of laser triangulation measurement system based on linear array CCD, and the correctness of the theoretical analysis and the feasibility of the design will be verified by the experiments. The principle of optical system of direct-incident laser triangulation measurement is analyzed theoretically from laser triangulation measurement principle and practical measurement requirement. A measurement system, which consists of a semiconductor laser source, an imaging Plano-convex lens, and a high-speed linear CCD, is designed. In these experiments, the high-speed linear array CCD optoelectronic data are obtained by acquisition and transmission system of USB interface. Through the corresponding relation between displacement variation of measured object and the pixel position of laser spot imaging on linear CCD, the measurement system uses the different fitting equations to be calibrated. Comparing displacement variation of the calibration results calculating with the actual one, the results shows that the measurement precision of using the four fitting can reach 0.47mm, the range of measuring is 200mm. The results show that the measurement system is correct and valid for medium displacement measurement.

  9. Fiber optic probes for tissue illumination in photodynamic diagnosis and therapy

    NASA Astrophysics Data System (ADS)

    Baumgartner, Reinhold; Beyer, Wolfgang; Friedsam, G.; Jocham, Dieter; Noack, Axel; Sroka, Ronald; Stepp, Herbert G.; Unsoeld, Eberhard

    1992-08-01

    Photodynamic diagnosis (PDD) and therapy (PDT) require light application devices which enable homogeneous illumination of tissue in hollow organs. Three techniques based on modification of the aperture of single fibers are presented mainly for use in urology and pneumology in combination with rigid and flexible endoscopes. All illumination systems allow for nearly entire illumination of the endoscope's viewing field. A microlens system is used for fluorescence diagnostic purposes in the lung. The system, consisting of two plano convex lenses in a condenser configuration, is attached directly to the fiber. The beam profile is optimized by ray tracing calculations. For fluorescence excitation of the tumormarker Photofrin II in the urinary bladder a 500 micrometers plastic fiber is used. The tip of the fiber is polished to a double cone with angles of 12 degree(s) and 7 degree(s). With this modification the aperture is increased by a factor of two. Photodynamic treatment of confined superficial tumors in the lung was successfully performed with a fused silica fiber coupled to the endoscope in a special adaptive device. In this procedure laserlight at 630 nm is guided through the optics channel of rigid endoscopes. A homogeneous circular illumination pattern is obtained following exactly the deflection angle of the endoscope.

  10. Ultraviolet and short wavelength visible light exposure: why ultraviolet protection alone is not adequate.

    PubMed

    Reichow, Alan W; Citek, Karl; Edlich, Richard F

    2006-01-01

    The danger of exposure to ultraviolet (UV) radiation in both the natural environment and artificial occupational settings has long been recognized by national and international standards committees and worker safety agencies. There is an increasing body of literature that suggests that protection from UV exposure is not enough. Unprotected exposure to the short wavelengths of the visible spectrum, termed the "blue light hazard", is gaining acceptance as a true risk to long-term visual health. Global standards and experts in the field are now warning that those individuals who spend considerable time outdoors should seek sun filter eyewear with high impact resistant lenses that provide 100% UV filtration, high levels of blue light filtration, and full visual field lens/frame coverage as provided by high wrap eyewear. The Skin Cancer Foundation has endorsed certain sunglasses as "product[s]...effective [as] UV filter[s] for the eyes and surrounding skin". However, such endorsement does not necessarily mean that the eyewear meets all the protective needs for outdoor use. There are several brands that offer products with such protective characteristics. Performance sun eyewear by Nike Vision, available in both corrective and plano (nonprescription) forms, is one such brand incorporating these protective features. PMID:17073573