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Sample records for 238u-230th-226ra discussions sur

  1. Mid-ocean ridge basalt generation along the slow-spreading, South Mid-Atlantic Ridge (5-11°S): Inferences from 238U-230Th-226Ra disequilibria

    NASA Astrophysics Data System (ADS)

    Turner, Simon; Kokfelt, Thomas; Hauff, Folkmar; Haase, Karsten; Lundstrom, Craig; Hoernle, Kaj; Yeo, Isobel; Devey, Colin

    2015-11-01

    U-series disequilibria have provided important constraints on the physical processes of partial melting that produce basaltic magma beneath mid-ocean ridges. Here we present the first 238U-230Th-226Ra isotope data for a suite of 83 basalts sampled between 5°S and 11°S along the South Mid-Atlantic Ridge. This section of the ridge can be divided into 5 segments (A0-A4) and the depths to the ridge axis span much of the global range, varying from 1429 to 4514 m. Previous work has also demonstrated that strong trace element and radiogenic isotope heterogeneity existed in the source regions of these basalts. Accordingly, this area provides an ideal location in which to investigate the effects of both inferred melt column length and recycled materials. 226Ra-230Th disequilibria indicate that the majority of the basalts are less than a few millennia old such that their 230Th values do not require any age correction. The U-Th isotope data span a significant range from secular equilibrium up to 32% 230Th excess, also similar to the global range, and vary from segment to segment. However, the (230Th/238U) ratios are not negatively correlated with axial depth and the samples with the largest 230Th excesses come from the deepest ridge segment (A1). Two sub-parallel and positively sloped arrays (for segments A0-2 and A3 and A4) between (230Th/238U) and Th/U ratios can be modelled in various ways as mixing between melts from peridotite and recycled mafic lithologies. Despite abundant evidence for source heterogeneity, there is no simple correlation between (230Th/238U) and radiogenic isotope ratios suggesting that at least some of the trace element and radiogenic isotope variability may have been imparted to the source regions >350 kyr prior to partial melting to produce the basalts. In our preferred model, the two (230Th/238U) versus Th/U arrays can be explained by mixing of melts from one or more recycled mafic lithologies with melts derived from chemically heterogeneous

  2. 238U- 230Th- 226Ra disequilibrium in young Mt. Shasta andesites and dacites

    NASA Astrophysics Data System (ADS)

    Volpe, Alan M.

    1992-11-01

    The paper describes 238U-series nuclides and 230Th/ 232Th ratios measured by mass spectrometry in mineral separates of young Mt. Shasta andesites and dacites. The results constrain the timing of recent calc-alkaline magma fractionation at this volcano. Hotlum, Misery Hill and Black Butte rocks show small, < 13% 230Th- 238U and < 6% 226Ra- 230Th, disequilibria. Plagioclase have 7-26% 226Ra excesses, magnetite and groundmass have 4-5% 226Ra deficits, and pyroxenes have equilibrium ( 226Ra/ 230Th) activity ratios. Internal ( 230Th)-( 238U)and Ba-normalized ( 226Ra)-( 230Th) isotope diagrams for Hotlum and Black Butte dacites suggest that closed-system Th-U and Ra-Th fractionation occurred less than 10,000 years ago. Significant 226Ra- 230Th disequilibria in the Black Butte dacite strongly suggests that this rock erupted more recently than 9400 years ago. Results for Hotlum andesites suggest a longer pre-eruption crystal residence time compared to the dacites. There may also have been recent open Ra-Th system changes in the melt composition. Initial Th/U ratios for the rocks are low (2.43-2.57), similar to those in mid-ocean ridge basalts (MORB), and preclude significant assimilation of crust with markedly different Th-U composition.

  3. 238U-230Th-226Ra disequilibria in dacite and plagioclase from the 2004-2005 eruption of Mount St. Helens: Chapter 36 in A volcano rekindled: the renewed eruption of Mount St. Helens, 2004-2006

    USGS Publications Warehouse

    Cooper, Kari M.; Donnelly, Carrie T.

    2008-01-01

    230Th)/(232Th) measured for the 1980s reference suite. However, (230Th)/(232Th) for plagioclase separates for dome samples erupted during October and November 2004 are significantly different from corresponding whole-rock values, which suggests that a large fraction (>30 percent) of crystals in each sample are foreign to the host liquid. Furthermore, plagioclase in the two 2004 samples have U-series characteristics distinct from each other and from plagioclase in dacite erupted in 1982, indicating that (1) the current eruption must include a component of crystals (and potentially associated magma) that were not sampled by the 1980-86 eruption, and (2) dacite magmas erupted only a month apart in 2004 contain different populations of crystals, indicating that this foreign component is highly heterogeneous within the 2004-5 magma reservoir.

  4. DISCUSSION

    EPA Science Inventory

    This is an invited discussion of three invited papers on statistical disclosure limitation from the Second International Conference on Establishment Surveys, Buffalo, NY, June 2000. The three papers in this session deal with computing, estimates, and computing estimates in the c...

  5. Recent volcanic accretion at 9°N-10°N East Pacific Rise as resolved by combined geochemical and geological observations

    NASA Astrophysics Data System (ADS)

    Waters, C. L.; Sims, K. W. W.; Soule, S. A.; Blichert-Toft, J.; Dunbar, N. W.; Plank, T.; Prytulak, J.; Sohn, R. A.; Tivey, M. A.

    2013-08-01

    The ridge crest at 9°N-10°N East Pacific Rise (EPR) is dominated by overlapping lava flows that have overflowed the axial summit trough and flowed off-axis, forming a shingle-patterned terrain up to ˜2-4 km on either side of the axial summit trough. In this study, we employ 230Th-226Ra dating methods, in conjunction with geochemistry and seafloor geological observations, in an effort to discern the stratigraphic relationships between adjacent flows. We measured major and trace elements and 87Sr/86Sr, 143Nd/144Nd, 176Hf/177Hf, and 238U-230Th-226Ra for lava glass samples collected from several flow units up to ˜2 km away from the axial summit trough on the ridge crest at 9°50'N EPR. Statistical analysis of the 238U-230Th-226Ra data indicates that all but one measured sample from these flows cannot be resolved from the zero-age population; thus, we cannot confidently assign model ages to samples for discerning stratigraphic relationships among flows. However, because groups of samples can be distinguished based on similarities in geochemical compositions, particularly incompatible element abundances with high precision-normalized variability such as U and Th, and because the range of compositions is much greater than that represented by samples from the 1991-1992 and 2005-2006 eruptions, we suggest that the dive samples represent 6-10 eruptive units despite indistinguishable model ages. Geochemical variability between individual flows with similar ages requires relatively rapid changes in parental melt composition over the past ˜2 ka, and this likely reflects variations in the relative mixing proportions of depleted and enriched melts derived from a heterogeneous mantle source.

  6. Utilisation de traceurs radioactifs pour l'évaluation du recrutement des leucocytes et des échanges vasculaires au niveau d'organes in~vivo. Description d'une méthode et discussion des problèmes d'interprétation sur quelques exemples

    NASA Astrophysics Data System (ADS)

    Bureau, M. F.

    1997-03-01

    An experimental method using simultaneously different γ emiter tracers was developed to evaluate inflammation in vivo. Experiments were performed on the anaesthetized guinea-pig to test pulmonary effects of inflammatory agents. Red blood cells, albumin and inflammatory cells (platelets or leucocytes) radiolabelled with 99m technetium, 131 iodine and 111 indium respectively were injected i.v. Their radioactivities were measured on a pulmonary region by external detection and on blood samples in a well type counter. From these measurements variations of the lung contents in red blood cells, extravascular albumin and non circulating leucocytes during inflammatory stimulation were evaluated. These parameters axe indexes of blood perfusion, vascular exchanges and leucocyte sequestration respectively. Fiability of the method and meaning of the parameters evaluated are discussed. Une méthode expérimentale utilisant simultanément différents traceurs γ a été développée pour évaluer l'inflammation in vivo. Des expériences ont été réalisées chez le cobaye anesthésié pour tester l'effet pulmonaire d'agents inflammatoires. Des globules rouges, de l'albumine et des cellules inflammatoires (plaquettes ou leucocytes) radiomarqués respectivement au technetium 99m, à l'iode 131 et à l'indium 111 sont injectés i.v. Leurs radioactivités sont mesurées sur une région pulmonaire par détection externe et sur des échantillons sanguins au compteur puit. À partir de ces mesures sont évaluées les variations des contenus pulmonaires en globules rouges, en albumine extravasculaire et en leucocytes non circulants lors d'une stimulation inflammatoire. Ces paramètres sont corrélés aux modifications de la perfusion, des échanges vasculaires et de la séquestration leucocytaire. La fiabilité de la méthode et la signification des paramètres évalués sont discutées.

  7. Scored Discussions.

    ERIC Educational Resources Information Center

    Zola, John

    1992-01-01

    Suggests a classroom strategy to help students learn to analyze and discuss significant issues from history and current policy debates. Describes scored discussions in which small groups of students receive points for participation. Provides an example of a discussion on gold mining. Includes an agenda. Explores uses of scored discussions and…

  8. Rapid time scales of basalt to andesite differentiation at Anatahan volcano, Mariana Islands

    NASA Astrophysics Data System (ADS)

    Reagan, Mark; Tepley, Frank J.; Gill, James B.; Wortel, Matthew; Hartman, Brian

    2005-08-01

    We present comprehensive U-series data ( 238U- 234U- 230Th- 226Ra- 210Pb- 210Po and ( 230Th)/( 232Th)) for an andesite from an oceanic arc. The juvenile Anatahan andesite has U-Th systematics colinear with other historical Mariana volcanic rocks, and is most similar to those of the other volcano in the Mariana arc with a significant proportion of silicic andesite: Uracas. Like Uracas, the parental basalt for the Anatahan andesite was generated by relatively low degrees of flux melting from a source previously enriched in a sediment component from the subducting slab. However, the Anatahan andesite is much more strongly enriched in 226Ra over 230Th than Uracas lavas, and has one of the highest ( 226Ra)/( 232Th) ratios of siliceous andesites globally. The long-lived disequilibria between 238U- 230Th- 226Ra in the Anatahan andesite are inherited from basalt genesis, not created during differentiation or eruption. Thus, the time between genesis of the parental basalt and eruption of andesite at Anatahan is shorter than for Uracas. Moreover, the near-equilibrium ( 210Pb)/( 226Ra) value indicates that the magma body did not persistently lose or gain 222Rn for more than 2 years before eruption. This permits differentiation of the parental basalt to form andesite within this 2-year time period, although a differentiation time period between 100 and a few thousand years also is possible. The relative activities between 210Po and 210Pb suggest erupted scoria degassed Po less than most lavas despite eruption plume heights of ˜10 km, which further suggests an unusually rapid ascent before eruption. These data also show that juvenile material was ejected from the first day of the eruption. Phreatomagmatic ejecta overlying the main Anatahan scoria is strongly enriched in 210Po over 210Pb, indicating that a significant proportion of the Po degassed from rising magmas sublimes in its shallow fumarolic conduit system.

  9. Geochemical hosts of solubilized radionuclides in uranium mill tailings

    USGS Publications Warehouse

    Landa, E.R.; Bush, C.A.

    1990-01-01

    The solubilization and subsequent resorption of radionuclides by ore components or by reaction products during the milling of uranium ores may have both economic and environmental consequences. Particle-size redistribution of radium during milling has been demonstrated by previous investigators; however, the identification of sorbing components in the tailings has received little experimental attention. In this study, uranium-bearing sandstone ore was milled, on a laboratory scale, with sulfuric acid. At regular intervals, filtrate from this suspension was placed in contact with mixtures of quartz sand and various potential sorbents which occur as gangue in uranium ores; the potential sorbents included clay minerals, iron and aluminum oxides, feldspar, fluorspar, barite, jarosite, coal, and volcanic glass. After equilibration, the quartz sand-sorbent mixtures were separated from the filtrate and radioassayed by gamma-spectrometry to determine the quantities of 238U, 230Th, 226Ra, and 210Pb sorbed, and the radon emanation coefficients. Sorption of 238U was low in all cases, with maximal sorptions of 1-2% by the bentonite- and coal-bearing samples. 230Th sorption also was generally less than 1%; maximal sorption here was observed in the fluorspar-bearing sample and appears to be associated with the formation of gypsum during milling. 226Ra and 210 Pb generally showed higher sorption than the other nuclides - more than 60% of the 26Ra solubilized from the ore was sorbed on the barite-bearing sample. The mechanism (s) for this sorption by a wide variety of substrates is not yet understood. Radon emanation coefficients of the samples ranged from about 5 to 30%, with the coal-bearing samples clearly demonstrating an emanating power higher than any of the other materials. ?? 1990.

  10. Timescales of storage and recycling of crystal mush at Krafla Volcano, Iceland

    NASA Astrophysics Data System (ADS)

    Cooper, Kari M.; Sims, Kenneth W. W.; Eiler, John M.; Banerjee, Neil

    2016-06-01

    Processes in upper-crustal magma reservoirs such as recharge, magma mixing, recycling of previously crystallized material, and eruption affect both the physical state and the chemical composition of magmas. A growing body of evidence shows that crystals in intermediate or silicic volcanic rocks preserve records of these processes that may be obscured due to mixing in the liquid fraction of magmas. Fewer studies have focused on crystals in basaltic lavas, but these show evidence for a more subtle, but still rich record of magmatic processes. We present new 238U-230Th-226Ra data for plagioclase, combined with δ18O and trace-element measurements of the same crystal populations, from basalts erupted at Krafla Volcanic Center, Iceland. These data document the presence of multiple crystal populations within each sample, with chemical and oxygen isotope heterogeneity at a variety of scales: within individual crystals, between crystals in a given population, between crystal populations within the same sample, and between crystals in lavas erupted from different vents during the same eruption. Comparison to whole-rock or groundmass data shows that the majority of macroscopic crystals are not in trace-element or oxygen isotope equilibrium with their host liquids. The most likely explanation for these data is that the macroscopic crystals originated within a highly heterogeneous crystal mush in the shallow magma reservoir system. U-series and diffusion data indicate that the crystals (and therefore the mush) formed recently (likely within a few thousand years of eruption, and with a maximum age of 8-9 ka), and that the crystals resided in their host magma prior to eruption for decades to a few centuries at most. These data, in conjunction with other recent studies, suggest a model where erupted Icelandic magmas are the result of diverse magmas entering the crust, followed by complex interactions between melts and previously crystallized material at all crustal levels.

  11. Insights into the Galápagos plume from uranium-series isotopes of recently erupted basalts

    NASA Astrophysics Data System (ADS)

    Handley, Heather K.; Turner, Simon; Berlo, Kim; Beier, Christoph; Saal, Alberto E.

    2011-09-01

    Uranium-series isotopes (238U-230Th-226Ra-210Pb), major element, trace element, and Sr-Nd isotopic data are presented for recent (<60 years old) Galápagos archipelago basalts. Volcanic rocks from all centers studied (Fernandina, Cerro Azul, Sierra Negra, and Wolf Volcano) display 230Th excesses (4%-15%) and steep rare earth element (REE) patterns indicative of residual garnet during partial melting of their mantle source. Rare earth element modeling suggests that only a few percent of garnet is involved. Correlations between (238U/232Th), radiogenic isotopes and Nb/Zr ratio suggest that the U/Th ratio of these Galápagos volcanic rocks is primarily controlled by geochemical source variations and not fractionation during partial melting. The lowest (230Th/238U) ratio is not observed at Fernandina (the supposed center of the plume) but at the more geochemically "depleted" Wolf Volcano, further to the north. Small radium excesses are observed for all samples with (226Ra/230Th) ranging from 1.107 to 1.614. The 226Ra-230Th disequilibria do not correlate with other uranium-series parent-daughter nuclide pairs or geochemical data, suggesting modification at shallow levels on timescales relevant to the half-life of 226Ra (1600 years). The combination of 226Ra and 210Pb excesses is inconsistent with interaction of magma with cumulate material unless decoupling of 210Pb (or an intermediate daughter, such as 222Rn) occurs prior to modification of Ra-Th disequilibria. An intriguing correlation of (210Pb/226Ra)0 with Nb/Zr and radiogenic isotopes requires further investigation but suggests possible control via magmatic degassing and accumulation that may somehow be related to source heterogeneities.

  12. Reframing Discussions

    ERIC Educational Resources Information Center

    Sherry, Michael B.

    2010-01-01

    Recitations and discussions are two types of interactions which have long been of interest to researchers who study classroom discourse in secondary English and Social Studies. According to research, teachers control the discourse during recitations through "inauthentic" questions requiring pre-specified answers. In contrast, discussions involve…

  13. Strengthening Discussions

    ERIC Educational Resources Information Center

    Hintz, Allison B.

    2013-01-01

    "Strategy sharing" is a certain type of discussion that centers on students' ideas and occurs when children present different approaches to problems and provide information about how they solved the problem (Wood, Williams, and McNeal 2004). A teacher may orchestrate a strategy-sharing discussion to achieve one or more of the…

  14. Orchestrating Discussions

    ERIC Educational Resources Information Center

    Smith, Margaret S.; Hughes, Elizabeth K.; Engle, Randi A.; Stein, Mary Kay

    2009-01-01

    The premise underlying this article is that identifying and using the "five practices model" can make discussions of cognitively challenging tasks more manageable for teachers. By giving teachers a roadmap that they can follow before and during whole-class discussions, these practices have the potential for helping teachers more effectively…

  15. Summary discussions

    SciTech Connect

    Ritchie, R.H.

    1982-01-01

    Remarks intended to highlight topics of importance for future research were made by three of the participants at the conclusion of the Seminar. A brief listing is given of topics discussed by each of these rapporteurs.

  16. Developing Discussion

    ERIC Educational Resources Information Center

    Maloch, Beth; Bomer, Randy

    2012-01-01

    Researchers and educators have long argued for the importance of providing time and space for rich conversations around literature. This column draws on research to consider how teachers make room for these discussions inside their classrooms. Particularly, the authors consider different dimensions along which teachers might examine and grow…

  17. Case Discussion

    PubMed Central

    Christmas, Colleen; Mears, Simon C.; Sieber, Frederick E.; Votsis, Julie; Wood, Ronald C.; Friedman, Susan M.

    2011-01-01

    This case presents a discussion of a 92-year-old man with multiple comorbidities, who presents with a subtrochanteric fracture. His course is complicated by large volume blood loss intraoperatively, requiring intensive care unit (ICU) monitoring postoperatively. His course is also complicated by delirium. PMID:23569687

  18. Risky Discussions

    ERIC Educational Resources Information Center

    Cook, Julian; Jacobs, Neil

    2006-01-01

    This article considers a hypothetical decision by a hypothetical learner about whether or not to participate in an online "discussion", viewed through the lens of risk analysis. It begins with the premise that participation online is desirable but that it involves the participant in risk, a fact that needs to be acknowledged and taken into account…

  19. [Discussing abortion].

    PubMed

    1997-01-01

    Discussions with several groups of low-income, middle-aged women in various countries of Latin America showed that most disapproved of abortion. In the course of group discussions about the motives of women who seek abortions and the psychological and sanitary conditions under which abortion occurs, however, their disapproval became less categorical. They began to accept the need to decriminalize abortion in order to protect women. The majority, strongly influenced by the Catholic Church, believed that human life begins at conception. Others disapproved of abortion because they feared it would be used as a birth control method and would encourage promiscuity. Most disapproved of abortion for single women attempting to escape family or social censure of unmarried motherhood. Fear of health effects or death from abortion and fear of divine punishment were also mentioned. Recognition of the anguish and pain suffered by women deciding to seek abortion and the difficulty of providing for the material and other needs of many children were factors that led to reconsideration of the wholesale condemnation of abortion. The women realized that such condemnations never take the woman's circumstances into account. Some of the women felt that aborting an unwanted pregnancy would be preferable to abandoning or neglecting an unwanted child. Many of the women came to feel that abortion should be legalized at least under some circumstances. PMID:12348503

  20. Localization of sulfonylurea receptor subunits, SUR2A and SUR2B, in rat heart.

    PubMed

    Zhou, Ming; He, Hui-Jing; Suzuki, Ryoji; Liu, Ke-Xiang; Tanaka, Osamu; Sekiguchi, Masaki; Itoh, Hideaki; Kawahara, Katsumasa; Abe, Hiroshi

    2007-08-01

    To understand the possible functions and subcellular localizations of sulfonylurea receptors (SURs) in cardiac muscle, polyclonal anti-SUR2A and anti-SUR2B antisera were raised. Immunoblots revealed both SUR2A and SUR2B expression in mitochondrial fractions of rat heart and other cellular fractions such as microsomes and cell membranes. Immunostaining detected ubiquitous expression of both SUR2A and SUR2B in rat heart in the atria, ventricles, interatrial and interventricular septa, and smooth muscles and endothelia of the coronary arteries. Electron microscopy revealed SUR2A immunoreactivity in the cell membrane, endoplasmic reticulum (ER), and mitochondria. SUR2B immunoreactivity was mainly localized in the mitochondria as well as in the ER and cell membrane. Thus, SUR2A and SUR2B are not only the regulatory subunits of sarcolemmal K(ATP) channels but may also function as regulatory subunits in mitochondrial K(ATP) channels and play important roles in cardioprotection. PMID:17438353

  1. AirMSPI PODEX BigSur Terrain Images

    Atmospheric Science Data Center

    2013-12-13

    ... from the PODEX 2013 Campaign   Big Sur target (Big Sur, California) 02/03/2013 Terrain-projected   Select ...   Version number   For more information, see the Data Product Specifications (DPS)   ...

  2. Using short-lived nuclides of the U- and Th-series to probe the kinetics of colloid migration in forested soils

    NASA Astrophysics Data System (ADS)

    Rihs, Sophie; Prunier, Jonathan; Thien, Bruno; Lemarchand, Damien; Pierret, Marie-Claire; Chabaux, François

    2011-12-01

    The recent chemical dynamics of a podzolic forest soil section (from the Strengbach watershed, France) was investigated using U- and Th-series nuclides. Analyses of ( 238U), ( 230Th), ( 226Ra), ( 232Th), ( 228Ra) and ( 228Th) activities in the soil particles, the seepage waters, and the mature leaves of the beech trees growing on this soil were performed by TIMS or gamma spectrometry. The simultaneous analysis of the different soil ( sl) compartments allows to demonstrate that a preferential Th leaching over Ra must be assumed to explain the ( 226Ra/ 230Th), ( 228Ra/ 232Th) and ( 228Th/ 228Ra) disequilibria recorded in the soil particles. The overall Ra- and Th- transfer schemes are entirely consistent with the prevailing acido-complexolysis weathering mechanism in podzols. Using a continuous open-system leaching model, the ( 226Ra/ 230Th) and ( 228Ra/ 232Th) disequilibria measured in the different soil layers enable dating of the contemporary processes occurring in this soil. In this way, we have determined that a preferential Th-leaching from the shallow Ah horizon, due to a strong complexation with organic colloids, began fairly recently (18 years ago at most). The continual increase in pH recorded in precipitations over the last 20 years is assumed to be the cause of this enhanced organic complexation. A lower soil horizon (50-60 cm) is also affected by preferential Th leaching, though lasting over several centuries at least, with a much smaller leaching rate. The migration of Th isotopes through this soil section might hence be used as a tracer for the organic colloids migration and the induced radioactive disequilibria demonstrate to be useful for assessing the colloidal migration kinetics in a forested soil. Ra and Th isotopic ratios also appear to be valuable tracers of some mineral-water-plant interactions occurring in soil. The ( 228Ra/ 226Ra) ratio enables discrimination of the Ra flux originating from leaf degradation from that originating from mineral

  3. 238U-230Th equilibrium in arc magmas and implications for the time scales of mantle metasomatism

    NASA Astrophysics Data System (ADS)

    Reubi, Olivier; Sims, Kenneth W. W.; Bourdon, Bernard

    2014-04-01

    Large excesses of 238U and 226Ra relative to 230Th characterize many arc magmas and are commonly interpreted to represent recent addition of slab-derived fluid to the mantle wedge beneath the arc. A significant proportion of arc magmas are, however, in 238U-230Th radioactive equilibrium. This is generally thought to result from “buffering” of the young slab fluid U-series signal by a sediment component in secular equilibrium. Here we present new 238U-230Th-226Ra and 235U-231Pa measurements for historic andesites from Volcán de Colima, Mexico. In all lavas (230Th/238U) are in equilibrium, whereas (231Pa/235U) and (226Ra/230Th) are significantly greater than one. These data demonstrate that arc magmas with (230Th/238U) equilibrium can have significant 231Pa and 226Ra excesses, precluding ageing of the magmas in the crust as the cause of 230Th/238U equilibrium. Quantitative modeling of metasomatic and melting processes further indicates that addition of sediment melts to a depleted mantle wedge produces significant 230Th excesses and that 238U excesses induced by recent addition of fluids derived from the altered oceanic crust are not sufficient to compensate these 230Th excesses. U-series activity ratios in Colima magmas are best explained by models in which the metasomatised mantle returns to secular equilibrium before melting, implying a time lag ⩾350 kyr, with subsequent production of 231Pa and 226Ra excesses by in-growth during melting rather than by addition of slab fluids. Investigation of a global compilation of U-series data in arc magma indicates that our model proposed for Colima applies to most arc magmas in or near (230Th-238U) equilibrium. The time lag between mantle metasomatism and melting appears to vary between hundreds years to more than 350 kyr in subduction zones. We posit that the absence of U/Th elemental fractionation during melting of arc sources in (230Th/238U) equilibrium reflects a higher fO2 compared to MORB sources that yield

  4. 231Pa systematics in postglacial volcanic rocks from Iceland

    NASA Astrophysics Data System (ADS)

    Turner, Simon; Kokfelt, Thomas; Hoernle, Kaj; Lundstrom, Craig; Hauff, Folkmar

    2016-07-01

    Several recent studies have highlighted the potential of combined 238U-230Th and 235U-231Pa systematics to constrain upwelling rates and the role of recycled mafic lithologies in mantle plume-derived basalts. Accordingly, we present measurements of the 231Pa concentrations from 26 mafic volcanic rocks from Iceland, including off-axis basalts from the Snaefellsnes Peninsula, to complement previously published 238U-230Th-226Ra data. 231Pa concentrations vary from 27 to 624 fg/g and (231Pa/235U) ratios from 1.12 to 2.11 with the exception of one anomalous sample from the Southeast Rift which has a 231Pa deficit with (231Pa/235U) = 0.86. An important new result is that basalts from the Southeast Rift and the Snaefellsnes Peninsula define a trend at relatively low (231Pa/235U) for a given (230Th/238U) ratio. Many of the remaining samples fall in or around the global field for ocean island basalts but those from the Mid-Iceland Belt and the Southwest Rift/Reykjanes Peninsula extend to higher (231Pa/235U) ratios at a given (230Th/238U), similar to mid-ocean ridge basalts. In principle, these lavas could result from melting of peridotite at lower pressures. However, there is no reason to suspect that the Mid-Iceland Belt and the Southwest Rift lavas reflect shallower melting than elsewhere in Iceland. In our preferred model, these lavas reflect melting of garnet peridotite whereas those from the Southeast Rift and the Snaefellsnes Peninsula contain a significant contribution (up to 20%) of melt from garnet pyroxenite. This is consistent with incompatible trace element and radiogenic isotope evidence for recycled oceanic crust in these lavas. There is increasing agreement that the displacement of ocean island basalts to lower (231Pa/235U) ratios at a given (230Th/238U), compared to mid-ocean ridge basalts, reflects the role of recycled mafic lithologies such as garnet pyroxenite as well as higher average pressures of melting. It now seems likely that this interpretation may

  5. Internet Discussion Groups.

    ERIC Educational Resources Information Center

    Bull, Glen; Bull, Gina; Sigmon, Tim

    1997-01-01

    Discusses newsgroups, listservs, and Web-based discussion groups. Highlights include major categories of international USENET discussion groups; newsgroups versus mailing lists; newsreaders; news servers; newsgroup subscriptions; newsgroups versus Web discussion groups; linking newsgroups, mailing lists, and the Web; and setting up a news host. A…

  6. Framing Evolution Discussion Intellectually

    ERIC Educational Resources Information Center

    Oliveira, Alandeom W.; Cook, Kristin; Buck, Gayle A.

    2011-01-01

    This study examines how a first-year biology teacher facilitates a series of whole-class discussions about evolution during the implementation of a problem-based unit. A communicative theoretical perspective is adopted wherein evolution discussions are viewed as social events that the teacher can frame intellectually (i.e., present or organize as…

  7. Curriculum for Discussion Time.

    ERIC Educational Resources Information Center

    Steinhoff, Mary E.

    This curriculum guide consists of materials for use in implementing two 10-meeting series of group discussions designed to enhance the process of the socialialization of students enrolled in an associate degree nursing program. Addressed in the discussion sessions are the following topics: developing an awareness of self-concept and gaining…

  8. Sur8 mediates tumorigenesis and metastasis in colorectal cancer

    PubMed Central

    Lee, Young-Mi; Kaduwal, Saluja; Lee, Kug Hwa; Park, Jong-Chan; Jeong, Woo-Jeong; Choi, Kang-Yell

    2016-01-01

    Sur8, a scaffold protein of the Ras pathway, interacts with Ras and Raf and modulates the Ras-extracellular signal-regulated kinase (ERK) pathway. Here we show that Sur8 is overexpressed in established human colorectal cancer (CRC) cell lines and CRC patient tissues. Moreover, Sur8 expression is increased during liver metastasis in CRC patients. Sur8 knockdown decreases ERK and Akt activities in CRC cell lines, regardless of their K-Ras, B-Raf or PI3K mutation status. Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of CRC cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC cells. Subcutaneous or orthotopic injection of HCT116 cells harboring a doxycycline (Dox)-mediated Sur8 knockdown system in nude mice resulted in decreased tumorigenic potential and inhibited the liver metastatic potential of HCT116 cells. Taken together, our data support the role of Sur8 as a promoter of tumorigenesis and liver metastasis in CRC through its modulation of the Ras-ERK and PI3K-Akt signaling pathways. PMID:27469030

  9. Sur8 mediates tumorigenesis and metastasis in colorectal cancer.

    PubMed

    Lee, Young-Mi; Kaduwal, Saluja; Lee, Kug Hwa; Park, Jong-Chan; Jeong, Woo-Jeong; Choi, Kang-Yell

    2016-01-01

    Sur8, a scaffold protein of the Ras pathway, interacts with Ras and Raf and modulates the Ras-extracellular signal-regulated kinase (ERK) pathway. Here we show that Sur8 is overexpressed in established human colorectal cancer (CRC) cell lines and CRC patient tissues. Moreover, Sur8 expression is increased during liver metastasis in CRC patients. Sur8 knockdown decreases ERK and Akt activities in CRC cell lines, regardless of their K-Ras, B-Raf or PI3K mutation status. Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of CRC cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC cells. Subcutaneous or orthotopic injection of HCT116 cells harboring a doxycycline (Dox)-mediated Sur8 knockdown system in nude mice resulted in decreased tumorigenic potential and inhibited the liver metastatic potential of HCT116 cells. Taken together, our data support the role of Sur8 as a promoter of tumorigenesis and liver metastasis in CRC through its modulation of the Ras-ERK and PI3K-Akt signaling pathways. PMID:27469030

  10. Deliberative Discussion Focus Groups.

    PubMed

    Rothwell, Erin; Anderson, Rebecca; Botkin, Jeffrey R

    2016-05-01

    This article discusses a new approach for the conduct of focus groups in health research. Identifying ways to educate and inform participants about the topic of interest prior to the focus group discussion can promote more quality data from informed opinions. Data on this deliberative discussion approach are provided from research within three federally funded studies. As healthcare continues to improve from scientific and technological advancements, educating the research participants prior to data collection about these complexities is essential to gather quality data. PMID:26078330

  11. Adolescence et pornographie sur la toile

    PubMed Central

    Haza, Marion

    2012-01-01

    Dans cet article, nous abordons la question de l’accès à la pornographie sur Internet par les adolescents. Nous déclinons plusieurs facettes de ces rencontres: la rencontre «fortuite», quand les adolescents sont confrontés à des images intempestives, des publicités ou spams avec des contenus pornographiques; la rencontre «spectatrice», quand les adolescents cherchent activement des vidéos ou photos mettant en scène la sexualité; et enfin la rencontre «actrice», quand les adolescents se mettent en scène eux-mêmes, seuls ou à plusieurs, de façon pornographique sur le Net. A partir d’exemple, nous réfléchissons aux enjeux de ces rencontres virtuelles précoces de la sexualité adulte par rapport au développement adolescent et à la représentation de leur propre sexualité en construction. PMID:22876261

  12. Regard sur les lazarets en terre canadienne

    PubMed Central

    Milot, Jean

    2008-01-01

    Puisant dans les nombreuses références qu’offrent les publications médicales canadiennes du milieu du XIXe siècle à nos jours, l’auteur fait découvrir l’existence de lazarets en terre canadienne, décrit l’impact de la maladie sur les conditions vie des lépreux qui y étaient confinés et en souligne les contrecoups tant sur le plan physique et psychologique que social. Il présente un bref aperçu de la maladie, ses symptômes, ses signes ainsi que ses complications oculaires et rappelle les premiers moyens thérapeutiques à base d’huile de chaulmoogra introduits dans la colonie de Tracadie vers 1901. Il illustre son propos en évoquant la vie dans les lazarets de l’île de Sheldrake (1844–1848) et de Tracadie (1848–1965) au Nouveau-Brunswick, puis dans ceux des îles D’Arcy (1891–1924) et de Bentinck (1924–1957) en Colombie-Britannique. PMID:19352451

  13. Designing "Educationally Effective" Discussion

    ERIC Educational Resources Information Center

    Swann, Joan

    2007-01-01

    This paper analyses data from a curriculum intervention project designed to introduce new forms of discussion, seen as educationally effective, into the primary classroom. While the introduction of talk as an aid to learning is premised on a social approach to learning, such interventions are often evaluated in terms of cognitive benefits and…

  14. Framing Discussions about Teaching

    ERIC Educational Resources Information Center

    Danielson, Charlotte

    2015-01-01

    Danielson's Framework for Teaching has provided a common language for discussions of teaching practice for almost 20 years. Many educators love the Framework's comprehensiveness; they find the specific language to be useful as they strive to improve their practice. For other educators, however, the Framework's 22 components and 76 smaller elements…

  15. Promoting Lively Literature Discussion

    ERIC Educational Resources Information Center

    Gritter, Kristine

    2011-01-01

    When students create personal connections with literature during whole-class discussion, they make sense both of text and of their life experiences. In this article, the author shares tips that help students make text-to-self, text-to-world, and text-to-text connections. She offers classroom examples to illustrate how conversations that encourage…

  16. [Discussion paper participation research].

    PubMed

    Farin, Erik

    2012-12-01

    This contribution introduces the "Diskussionspapier Teilhabeforschung" (discussion paper participation research) of the German Association for Rehabilitation (DVfR) and German Society for Rehabilitation Science (DGRW). The aim of this paper is to more clearly define current scientific research activity on the subject of participation and the significance of interdisciplinary participation research. The authors emphasise the desirability of a stronger scientific basis for instruments designed to improve the participation of disabled individuals. The paper is meant to be understood as an initial basis for the discussion about participation research development, and the authors are open to suggestions and elaboration.Participation research is understood in this discussion paper as an interdisciplinary research field with 7 goals and characteristics: 1. focussing on participation and self-determination; 2. contextual approach (taking environmental and personal factors into consideration that affect participation); 3. the participation of disabled persons in participation research; 4. interdisciplinary cooperation; 5. involving organisations and institutions whose approaches to participation research overlap; 6. referring to social and healthcare policies; 7. national and international orientations.The authors discuss the rationale behind increasing the support for participation research and theoretical models thereof. Fundamental concepts with high relevance to participation research include the biopsychosocial model of the International Classification of Functionality, Disability and Health (ICF), the inclusion concept, empowerment concept, and capabilities concept. The authors conclude their paper with recommendations for strengthening the research funding for participation research, and specify concrete steps toward greater participation research. PMID:23235948

  17. Mini-Discussion Summaries

    ERIC Educational Resources Information Center

    Maston, Robert C.; Hagenbuch, Barbara A.

    1976-01-01

    Mini-discussions were held at the 62nd Annual Meeting of the Association of American Colleges and were intended as continuations of the general sessions. Topics included: educational implications of the limits to growth; changes in our operative social values; dilemmas and strategies for American higher education in the next century. (LBH)

  18. Discussions That Drive Democracy

    ERIC Educational Resources Information Center

    Hess, Diana

    2011-01-01

    Adults in the United States have been migrating to ideologically homogenous communities, a phenomenon that researchers have called "the big sort." Thus, the need for young Americans to engage in civil discussion of controversial issues has never been greater. Public schools are an ideal place to undo the big sort because controversial issues fit…

  19. A Discussion of "Ceremony."

    ERIC Educational Resources Information Center

    Sands, Kathleen M., Ed.; Ruoff, A. Lavonne, Ed.

    1979-01-01

    Seminar participants discuss the novel "Ceremony" as a curing ceremony, the function of memory in the novel, and the distinctly American Indian aspects of the novel (role of animals, circular images, ritual, mythology, Laguna cultural traditions, and use of oral tradition). (CM)

  20. Facilitating Productive Discussions

    ERIC Educational Resources Information Center

    Cengiz, Nesrin

    2013-01-01

    Whole-group classroom discussions about solutions allow teachers to promote reasoning that moves students beyond merely noticing mathematical ideas toward developing a well-connected knowledge of concepts. Creating classroom environments where teachers promote reasoning and engage students in investigating important mathematical phenomena is…

  1. John Cage Discusses Fluxus.

    ERIC Educational Resources Information Center

    Snyder, Ellsworth

    1992-01-01

    Presents an informal discussion with composer John Cage which includes his response to George Maciunas' work, his recollections of Marcel Duchamp, the complex relationship between inelegant material and revealing works of art, neo-Dada and neo-Fluxus, Wittgenstein and the artist's ultimate responsibility to initiate a change in the viewer or…

  2. Lithiase géante sur enterocystoplastie

    PubMed Central

    Elmortaji, Khalid; Elomri, Ghassane; Bennani, Saad; Rabii, Redouane; Aboutaib, Rachid; Meziane, Fethi

    2014-01-01

    La formation des lithiases est une complication fréquente des entérocystoplasties après cystectomie radicale pour tumeur de vessie infiltrante. Le délai d'apparition dépend des facteurs de risque favorisants notamment les infections urinaires. Néanmoins la survenue de lithiase géante sur néovessie reste exceptionnelle, seulement 5 cas ont été rapportés dans la littérature. Nous rapportons dans ce travail, le cas d'une lithiase géante compliquant une entérocystoplastie chez un malade suivi pour tumeur de vessie infiltrante. PMID:25932070

  3. Summaries of group discussions

    NASA Technical Reports Server (NTRS)

    Jensen, L. D.

    1972-01-01

    Group discussions following the presentations of reports on the remote sensing of Chesapeake Bay resources are presented. The parameters to be investigated by the remote sensors and the specifications of the sensors are described. Specific sensors for obtaining data on various aspects of the ecology are identified. Recommendations for establishing a data bank and additional efforts to obtain increased understanding of the ecology are submitted.

  4. DISCUSSION ON MENINGITIS

    PubMed Central

    1929-01-01

    (1) Meningitis: two groups of cases. (2) A method of washing out the subarachnoid space in cases of septic meningitis secondary to infection of the ear. (3) Discussion on the value of maintaining a positive pressure of the cerebrospinal fluid when operating on a septic region communicating with the subarachnoid space. (4) Leaking cerebrospinal fluid from the region of the ear: operative treatment. PMID:19986899

  5. China's satellite communications discussed

    NASA Astrophysics Data System (ADS)

    Ruhou, Z.

    1986-04-01

    In 1972, China began to enter the age of satellite comunications, and it was realized that satellites could play a large role in television transmission in China. The experimental broadcasting of satellite television programs was begun in 1978, and satisfactory results were obtained. The success of the television transmission demonstration has led to important decisions regarding development of a domestic satellite communications system. Before specialized communications satellites are launched, the decision was made to lease an international communications satellite transmitter. The responsibility of the ground stations were discussed.

  6. Empowerment: a conceptual discussion.

    PubMed

    Tengland, Per-Anders

    2008-06-01

    The concept of 'empowerment' is used frequently in a number of professional areas, from psychotherapy to social work. But even if the same term is used, it is not always clear if the concept denotes the same goals or the same practice in these various fields. The purpose of this paper is to clarify the discussion and to find a plausible and useful definition of the concept that is suitable for work in various professions. Several suggestions are discussed in the paper, for example control over life or health, autonomy, ability, self-efficacy, self-esteem, and freedom, and it is concluded that there are two plausible complementary uses, one as a goal and one as a process or approach. Empowerment as a goal is to have control over the determinants of one's quality of life, and empowerment as a process is to create a professional relation where the client or community takes control over the change process, determining both the goals of this process and the means to use. PMID:17985247

  7. AirMSPI PODEX Big Sur Ellipsoid Images

    Atmospheric Science Data Center

    2013-12-11

    ... AirMSPI Browse Images from the PODEX 2013 Campaign   Big Sur target 02/03/2013 Ellipsoid-projected   Select ...   Version number   For more information, see the  Data Product Specifications (DPS) ...

  8. Low temperature benefits discussed.

    PubMed

    2016-03-01

    At a recent educational workshop event hosted by Advanced Sterilization Products, expert speakers including Authorising Engineers, and delegates, discussed some of their experiences of low temperature sterilisation of 'hi-tech' medical devices, and highlighted the benefits of a process which allows decontamination of instruments and, for example, parts of robotic surgery systems, that cannot be decontaminated using standard methods. Also examined,and reported on here in an article that first appeared in HEJ's sister publication, The Clinical Services Journal, were some of the disadvantages of low temperature sterilisation, the key considerations and options when choosing such a system, and a focus on how the technology's use had benefited a major London-based NHS Trust. PMID:27132304

  9. Lignes directrices canadiennes sur la rhinosinusite chronique

    PubMed Central

    Kaplan, Alan

    2013-01-01

    Résumé Objectif Présenter un résumé clinique des lignes directrices canadiennes sur la rhinosinusite chronique (RSC) qui comporte des recommandations pertinentes aux médecins de famille. Qualité des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique dans la littérature médicale et ont rédigé une ébauche de recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en contenu de l’extérieur, ainsi que l’aval des sociétés médicales (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Canadian Society of Otolaryngology—Head and Neck Surgery, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic d’une RSC se fonde sur le type et la durée des symptômes et une constatation objective d’une inflammation de la muqueuse nasale ou des sinus paranasaux. La rhinosinusite chronique est catégorisée en fonction de la présence ou de l’absence de polypes nasaux et cette distinction entraîne des différences dans le traitement. On traite la rhinosinusite chronique avec polypes nasaux au moyen de corticostéroïdes par voie intranasale. Des antibiotiques sont recommandés quand les symptômes indiquent une infection (douleur ou purulence). Pour une RSC sans polypes nasaux, on recommande des corticostéroïdes par voie intranasale et des antibiotiques de deuxième ligne (par ex. combinaisons amoxicilline–acide clavulanique ou fluoroquinolones à activité accrue contre Gram positif). Une irrigation avec une solution saline, des stéroïdes par voie orale et des tests d’allergies pourraient être appropriées. Si le patient ne répond pas au traitement, il faudrait envisager d

  10. Fires Burning near Big Sur, California

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Fires near Big Sur, Calif., continued to burn unchecked when the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument on NASA's Terra satellite captured this image on Sunday, June 29. In Northern California alone, fires have consumed more than 346,000 acres.At least 18,000 people have deployed to attempt to extinguish or control the flames. Air quality as far away as San Francisco has been adversely impacted by the dense clouds of smoke and ash blowing towards the northwest. The satellite image combines a natural color portrayal of the landscape with thermal infrared data showing the active burning areas in red. The dark area in the lower right is a previous forest fire.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

    Size: 35.4 by 57 kilometers (21.9 by 34.2 miles) Location: 36.1 degrees North latitude, 121.6 degrees West longitude Orientation: North at top Image Data: ASTER bands 3, 2, and 1 Original Data Resolution: 15 meters (49 feet) Dates Acquired: June 29

  11. Effets de la formation sur la violence conjugale

    PubMed Central

    Zaher, Eman; Keogh, Kelly; Ratnapalan, Savithiri

    2014-01-01

    interventions éducatives à multiples facettes prenaient la forme d’ateliers interactifs, d’apprentissage sur le web et de formation expérientielle. Une autre étude utilisait des discussions de groupes témoins et de la formation et a permis de constater une amélioration dans le signalement de la violence conjugale par les médecins. Les 2 autres études ont relevé une meilleure perception par les médecins en pratique de leur confiance en eux à l’aide d’apprentissage par problèmes en ligne. Conclusion Il a été difficile de déterminer quelle stratégie pédagogique était la plus efficace étant donné que les interventions éducatives et les mesures des résultats variaient entre les études choisies. De brèves interventions pour les médecins en formation postdoctorale amélioraient les connaissances mais ne semblaient pas influencer les comportements. La formation en ligne sous forme d’apprentissage par problèmes améliorait les perceptions des médecins en pratique, leurs connaissances et leurs habiletés quant à la prise en charge de la violence conjugale. La formation des médecins combinée à des interventions de soutien de la part du système semblait bénéfique aux victimes de violence conjugale et augmentait le nombre de demandes de consultations auprès des ressources de soutien à leur intention.

  12. Kir6.2 activation by sulfonylurea receptors: a different mechanism of action for SUR1 and SUR2A subunits via the same residues

    PubMed Central

    Principalli, Maria A; Dupuis, Julien P; Moreau, Christophe J; Vivaudou, Michel; Revilloud, Jean

    2015-01-01

    ATP-sensitive potassium channels (K-ATP channels) play a key role in adjusting the membrane potential to the metabolic state of cells. They result from the unique combination of two proteins: the sulfonylurea receptor (SUR), an ATP-binding cassette (ABC) protein, and the inward rectifier K+ channel Kir6.2. Both subunits associate to form a heterooctamer (4 SUR/4 Kir6.2). SUR modulates channel gating in response to the binding of nucleotides or drugs and Kir6.2 conducts potassium ions. The activity of K-ATP channels varies with their localization. In pancreatic β-cells, SUR1/Kir6.2 channels are partly active at rest while in cardiomyocytes SUR2A/Kir6.2 channels are mostly closed. This divergence of function could be related to differences in the interaction of SUR1 and SUR2A with Kir6.2. Three residues (E1305, I1310, L1313) located in the linker region between transmembrane domain 2 and nucleotide-binding domain 2 of SUR2A were previously found to be involved in the activation pathway linking binding of openers onto SUR2A and channel opening. To determine the role of the equivalent residues in the SUR1 isoform, we designed chimeras between SUR1 and the ABC transporter multidrug resistance-associated protein 1 (MRP1), and used patch clamp recordings on Xenopus oocytes to assess the functionality of SUR1/MRP1 chimeric K-ATP channels. Our results reveal that the same residues in SUR1 and SUR2A are involved in the functional association with Kir6.2, but they display unexpected side-chain specificities which could account for the contrasted properties of pancreatic and cardiac K-ATP channels. PMID:26416970

  13. Random assembly of SUR subunits in K(ATP) channel complexes.

    PubMed

    Cheng, Wayland W L; Tong, Ailing; Flagg, Thomas P; Nichols, Colin G

    2008-01-01

    Sulfonylurea receptors (SURs) associate with Kir6.x subunits to form tetradimeric K(ATP) channel complexes. SUR1 and SUR2 confer differential channel sensitivities to nucleotides and pharmacological agents, and are expressed in specific, but overlapping, tissues. This raises the question of whether these different SUR subtypes can assemble in the same channel complex and generate channels with hybrid properties. To test this, we engineered dimeric constructs of wild type or N160D mutant Kir6.2 fused to SUR1 or SUR2A. Dimeric fusions formed functional, ATP-sensitive, channels. Coexpression of weakly rectifying SUR1-Kir6.2 (WTF-1) with strongly rectifying SUR1-Kir6.2[N160D] (NDF-1) in COSm6 cells results in mixed subunit complexes that exhibit unique rectification properties. Coexpression of NDF-1 and SUR2A-Kir6.2 (WTF-2) results in similar complex rectification, reflecting the presence of SUR1- and SUR2A-containing dimers in the same channel. The data demonstrate clearly that SUR1 and SUR2A subunits associate randomly, and suggest that heteromeric channels will occur in native tissues. PMID:18690055

  14. Discussion.

    ERIC Educational Resources Information Center

    Davson-Galle, Peter

    2003-01-01

    Explains Philip Higgs' post modern pluralist thought by reaction to the monolithic rigidities of the decreed dogma of his country's (South Africa) past. Author argues that Higgs has overreacted and has become over tolerant of diversity of thought and that intellectual endeavors should be relativised to particular intellectual parochial…

  15. Discussion

    NASA Astrophysics Data System (ADS)

    Crawford, K.

    Presenter, T. P. Grazulis, private consultant [Grazulis et al., this volume, advances in tornado climatology, hazards, and risk assessment since Tornado Symposium II]. (C. Anderson, North Carolina State University.) At one time, I lived in Wisconsin and used to consider tornado climatology there. I noticed some very strange reporting, also. There were a number of counties along the Lake Michigan shore that showed no reported tornadoes from 1915 to 1950. Did you find something like this as well?

  16. Discussion.

    ERIC Educational Resources Information Center

    Higgs, Philip

    2003-01-01

    Author argues that the philosophical movement known as postmodernism seriously undermined the notion that truth can be at all objective and that truth depends entirely on democratic consensus. Addresses Davon-Galle's criticism of the author's assertions and explains that the certainty that Davon-Galle seeks is not to be found in philosophy or any…

  17. Human Cloning: Let's Discuss It.

    ERIC Educational Resources Information Center

    Taras, Loretta; Stavroulakis, Anthea M.; Ortiz, Mary T.

    1999-01-01

    Describes experiences with holding discussions on cloning at a variety of levels in undergraduate biology courses. Discusses teaching methods used and student reactions to the discussions. Contains 12 references. (WRM)

  18. Let's Discuss: Teaching Students about Discussions

    ERIC Educational Resources Information Center

    Brank, Eve; Wylie, Lindsey

    2013-01-01

    Research consistently demonstrates the benefits of employing classroom discussions; however, there has been less attention given to teaching students about discussions. The current research compared 2 advanced social psychology courses: 1 without (control) and 1 with (experimental) a week devoted to learning about and discussing discussions.…

  19. Finding the SurPriSe: A Case Study of a Faculty Learning Community

    ERIC Educational Resources Information Center

    Michel, Roberta M.

    2014-01-01

    This article details a faculty learning community (FLC) that started in 2009 on the campus of a Midwestern University and has evolved into an interdisciplinary research, teaching and social community of practice and learning called SurPriSe. SurPriSe is an acronym that reflects the interest area of the FLC; Sur for surveillance, Pri for privacy,…

  20. Introduction to Small Group Discussion.

    ERIC Educational Resources Information Center

    Millar, Dan Pyle

    To bring educational research into focus with tested classroom practice, this booklet provides an introduction to small group discussion. The theory and research section discusses the importance of small group discussion, characteristics of small group discussions, group attraction based on Maslow's hierarchy of basic human needs, group decision…

  1. The Sur1-Trpm4 Channel in Spinal Cord Injury.

    PubMed

    Simard, J Marc; Woo, Seung Kyoon; Aarabi, Bizhan; Gerzanich, Volodymyr

    2013-08-17

    Spinal cord injury (SCI) is a major unsolved challenge in medicine. Impact trauma to the spinal cord shears blood vessels, causing an immediate 'primary hemorrhage'. During the hours following trauma, the region of hemorrhage enlarges progressively, with delayed or 'secondary hemorrhage' adding to the primary hemorrhage, and effectively doubling its volume. The process responsible for the secondary hemorrhage that results in early expansion of the hemorrhagic lesion is termed 'progressive hemorrhagic necrosis' (PHN). PHN is a dynamic process of auto destruction whose molecular underpinnings are only now beginning to be elucidated. PHN results from the delayed, progressive, catastrophic failure of the structural integrity of capillaries. The resulting 'capillary fragmentation' is a unique, pathognomonic feature of PHN. Recent work has implicated the Sur1-Trpm4 channel that is newly upregulated in penumbral microvessels as being required for the development of PHN. Targeting the Sur1-Trpm4 channel by gene deletion, gene suppression, or pharmacological inhibition of either of the two channel subunits, Sur1 or Trpm4, yields exactly the same effects histologically and functionally, and exactly the same unique, pathognomonic phenotype - the prevention of capillary fragmentation. The potential advantage of inhibiting Sur1-Trpm4 channels using glibenclamide is a highly promising strategy for ameliorating the devastating sequelae of spinal cord trauma in humans. PMID:24834370

  2. A Discussion of Population Invariance

    ERIC Educational Resources Information Center

    Brennan, Robert L.

    2008-01-01

    The discussion here covers five articles that are linked in the sense that they all treat population invariance. This discussion of population invariance is a somewhat broader treatment of the subject than simply a discussion of these five articles. In particular, occasional reference is made to publications other than those in this issue. The…

  3. Round Table Discussion about JIS

    NASA Astrophysics Data System (ADS)

    Wöhl, H.

    After the talks about the CESAR Grid and the Joint Information System (JIS) a round table discussion was scheduled. The author, who was the convener of the discussion was asked to summarize the discussion: The main suggestions are to make access to JIS easier and especially give all users unlimited access to the personal data.

  4. Chemical Kinetics Laboratory Discussion Worksheet

    PubMed Central

    Demoin, Dustin Wayne; Jurisson, Silvia S.

    2013-01-01

    A laboratory discussion worksheet and its answer key provide instructors and students a discussion model to further the students’ understanding of chemical kinetics. This discussion worksheet includes a section for students to augment their previous knowledge about chemical kinetics measurements, an initial check on students’ understanding of basic concepts, a group participation model where students work on solving complex-conceptual problems, and a conclusion to help students connect this discussion to their laboratory or lecture class. Additionally, the worksheet has a detailed solution to a more advanced problem to help students understand how the concepts they have put together relate to problems they will encounter during later formal assessments. PMID:24092948

  5. Etude des effets du martelage repetitif sur les contraintes residuelles

    NASA Astrophysics Data System (ADS)

    Hacini, Lyes

    L'assemblage par soudage peut engendrer des contraintes residuelles. Ces contraintes provoquent des fissurations prematurees et un raccourcissement de la duree de vie des composants. Dans ce contexte, le martelage robotise est utilise pour relaxer ces contraintes residuelles. Trois volets sont presentes: le premier est l'evaluation des effets des impacts unitaires repetes sur le champ de contraintes developpe dans des plaques d'acier inoxydable austenitique 304L vierges ou contenant des contraintes residuelles initiales. Dans la deuxieme partie de ce projet, le martelage est applique grace au robot SCOMPI. Les contraintes residuelles induites et relaxees par martelage sont ensuite mesurees par la methode des contours, qui a ete adaptee a cet effet. Dans la troisieme partie, le martelage est modelise par la methode des elements finis. Un modele axisymetrique developpe grace au logiciel ANSYS permet de simuler des impacts repetes d'un marteau elastique sur une plaque ayant un comportement elastoplastique.

  6. Assessing Natural Radionuclide Migration in the Legacy Tailings of Uranium Production

    NASA Astrophysics Data System (ADS)

    Bondarenko, G.; Koliabina, I.; Marinich, O.

    2011-12-01

    - 230Th - 226Ra - 210Pb decay chain, typical for closed systems, has been disturbed during selective chemical uranium extraction from the parent ore. We calculated the migration of 210Pb, assuming constant 226Ra activity. The results of these calculations show that over 50 years, ~18% of the initial (unknown) 210Pb(0) activity was removed. If we assume removal of 226Ra decay products will continue at the current level, we expect the future annual activity loss of 210Pb to be about 0.36% per year, or 0.072 Bq/g. Assuming the examined core sample is representative of all 12 million tons of tails, the total annual activity loss is estimated to be ~1012 Bq/year. These results allow us to conclude that the loss of activity from the tailing pit by water migration is mainly associated with the 226Ra decay products: 222Rn, 210Pb, 210Po.
    Activity ratios, Dnieper tailings

  7. Measuring 226Ra/228Ra in Oceanic Lavas by MC-ICPMS

    NASA Astrophysics Data System (ADS)

    Standish, J. J.; Sims, K.; Ball, L.; Blusztajn, J.

    2007-12-01

    238U-230Th-226Ra disequilibrium in volcanic rocks provides an important and unique tool to evaluate timescales of recent magmatic processes. Determination of 230Th-226Ra disequilibria requires measurement of U and Th isotopes and concentrations as well as measurement of 226Ra. While measurement of U and Th by ICPMS is now well established, few published studies documenting 226Ra measurement via ICPMS exist. Using 228Ra as an isotope spike we have investigated two ion-counting methods; a 'peak-hopping' routine, where 226Ra and 228Ra are measured in sequence on the central discrete dynode ETP secondary electron multiplier (SEM), and simultaneous measurement of 226Ra and 228Ra on two multiple ion-counter system (MICS) channeltron type detectors mounted on the low end of the collector block. Here we present 226Ra measurement by isotope dilution using the Thermo Fisher NEPTUNE MC-ICPMS. Analysis of external rock standards TML and AThO along with mid-ocean ridge basalt (MORB) and ocean island basalt (OIB) samples show three issues that need to be considered when making precise and accurate Ra measurements: 1) mass bias, 2) background, and 3) relative efficiencies of the detectors when measuring in MICS mode. Due to the absence of an established 226Ra/228Ra standard, we have used U reference material NBL-112A to monitor mass bias. Although Ball et. al., (in press) have shown that U does not serve as an adequate proxy for Th (and thus not likely for Ra either), measurements of rock standards TML and AThO are repeatedly in equilibrium within the uncertainty of the measurements (where total uncertainty includes propagation of the uncertainty in the 226Ra standard used for calibrating the 228Ra spike). For this application, U is an adequate proxy for Ra mass bias at the 1% uncertainly level. The more important issue is the background correction. Because of the extensive chemistry required to separate and purify Ra (typically fg/g level in volcanic rocks), we observe large

  8. Experiential environmental learning: A case study of innovative pedagogy in Baja Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Schneller, Andrew Jon

    This mixed methods case study describes an innovative two-semester middle school environmental learning course that departs from traditional Mexican expository pedagogy through the incorporation of experiential and service learning. This research takes place in a small middle school in Pescadero, Baja California Sur, Mexico. The research approach utilized in the study adds to the handful of studies in this cross-disciplinary field by employing quantitative methodologies to measure course outcomes on student environmental knowledge, perceptions, and actions, while simultaneously qualitatively describing the behavioral, educational, environmental, and social experiences of students. This research employs Dewey's theories of experience---as well as those of more contemporary authenticity theorists---in order to identify the philosophies that advocate incorporating experiential pedagogy within the curriculum. Implications for Mexican educational policy, practical pedagogical applications, and theory are discussed.

  9. Techtalk: Expanding the Online Discussion.

    ERIC Educational Resources Information Center

    MacDonald, Lucy; Caverly, David C.

    2001-01-01

    Examines the use of "type 2 discussion," in which the teacher creates an online conversation with the class. Suggests that, by adding type 2 discussions to a face-to-face developmental education class, faculty help students build their own knowledge base. Adds that the online component gives all students equal access to this knowledge…

  10. Do Rewards Shape Online Discussions?

    ERIC Educational Resources Information Center

    Meyer, Katrina A.

    2008-01-01

    This research attempted to test whether the granting of points for receiving the most votes as the "best post" would affect the quality of subsequent postings to online discussions. Five online discussions were held in a small graduate-level course in leadership theory, and postings were coded into Bloom's taxonomy. Quality was defined…

  11. Promoting Discussions in ESL Students

    ERIC Educational Resources Information Center

    Navarro, Ann

    2010-01-01

    Background: Teachers who work with English as a Second Language (ESL) students, struggle with promoting discussion during guided reading. When ESL students are asked comprehension questions during group discussions and throughout the reading of a book, often teachers receive minimal feedback. Purpose: The purpose of this research is to identify…

  12. Acquiring Knowledge from Asynchronous Discussion

    ERIC Educational Resources Information Center

    Teo, Yiong Hwee; Webster, Len

    2008-01-01

    This article discusses a study which was designed to explore how online scaffolding can be incorporated to support knowledge acquisition in asynchronous discussion. A group of Singapore preservice teachers engaged in collaborative critiquing of videos before they embarked on their video projects to illustrate what constitutes good and bad video…

  13. Teacher Flexibility in Mathematical Discussion

    ERIC Educational Resources Information Center

    Leikin, Roza; Dinur, Sariga

    2007-01-01

    The significance of discussion in mathematics classes has been prominently debated in the research literature. Different studies have stressed the importance of teacher flexibility in orchestrating the discussion. We introduce an operational definition of teacher flexibility. In a case study with one secondary-school mathematics teacher, we…

  14. Summary of Linac Group discussions

    SciTech Connect

    Schaffer, G.

    1989-01-01

    This paper discusses upgrading of the LAMPF I linac. Particular topics discussed are: sources of and cures for linac beam halos, ion source, RFQ, chopper and drift-tube linac, cavity-coupled linac, superconducting linac structure, new rf power sources, EHF linac design, and cost projections. (LSP)

  15. Socrates, discussion and moral education

    NASA Astrophysics Data System (ADS)

    Rembert, Ron B.

    1995-01-01

    For Socrates, as he appears in Plato's dialogues, the process of discussion is essential for preparing human beings to lead a moral life. Only through discussion, Socrates maintains, can we be led to an understanding of such concepts as wisdom, courage and justice. The author of this article believes that the Socratic notion of the moral value of discussion is still valid. In support of this view, he examines two recent works: Dialogues on Moral Education by John Wilson and Barbara Cowell, and Moral Education, Secular and Religious by John L. Elias. Finally, the author suggests how the Socratic concept of dialogue might be used in moral education today.

  16. Effets des electrons secondaires sur l'ADN

    NASA Astrophysics Data System (ADS)

    Boudaiffa, Badia

    Les interactions des electrons de basse energie (EBE) representent un element important en sciences des radiations, particulierement, les sequences se produisant immediatement apres l'interaction de la radiation ionisante avec le milieu biologique. Il est bien connu que lorsque ces radiations deposent leur energie dans la cellule, elles produisent un grand nombre d'electrons secondaires (4 x 104/MeV), qui sont crees le long de la trace avec des energies cinetiques initiales bien inferieures a 20 eV. Cependant, il n'y a jamais eu de mesures directes demontrant l'interaction de ces electrons de tres basse energie avec l'ADN, du principalement aux difficultes experimentales imposees par la complexite du milieu biologique. Dans notre laboratoire, les dernieres annees ont ete consacrees a l'etude des phenomenes fondamentaux induits par impact des EBE sur differentes molecules simples (e.g., N2, CO, O2, H2O, NO, C2H 4, C6H6, C2H12) et quelques molecules complexes dans leur phase solide. D'autres travaux effectues recemment sur des bases de l'ADN et des oligonucleotides ont montre que les EBE produisent des bris moleculaires sur les biomolecules. Ces travaux nous ont permis d'elaborer des techniques pour mettre en evidence et comprendre les interactions fondamentales des EBE avec des molecules d'interet biologique, afin d'atteindre notre objectif majeur d'etudier l'effet direct de ces particules sur la molecule d'ADN. Les techniques de sciences des surfaces developpees et utilisees dans les etudes precitees peuvent etre etendues et combinees avec des methodes classiques de biologie pour etudier les dommages de l'ADN induits par l'impact des EBE. Nos experiences ont montre l'efficacite des electrons de 3--20 eV a induire des coupures simple et double brins dans l'ADN. Pour des energies inferieures a 15 eV, ces coupures sont induites par la localisation temporaire d'un electron sur une unite moleculaire de l'ADN, ce qui engendre la formation d'un ion negatif transitoire

  17. Three-phase Discussion Sessions.

    ERIC Educational Resources Information Center

    Karr, M. C.; And Others

    1988-01-01

    Describes the procedures, organizational pattern and design of basic soils course used by teaching assistants. Cites studies which support small-group discussion for promoting higher levels of intellectual functioning. Presents tables showing survey evaluation results of this method. (RT)

  18. Animating Geometry Discussions with Flexigons.

    ERIC Educational Resources Information Center

    McClintock, Ruth

    1994-01-01

    Presents activities with 10- and 4-straw flexigons, an object created by stringing together lengths of plastic drinking straws with nylon fishing line. Discusses several geometric theorems that can be demonstrated with flexigons. (MKR)

  19. Discussion: Confronting theory and experiment

    SciTech Connect

    Gallagher, Hugh; Hayato, Yoshinari; Sobczyk, Jan

    2015-05-15

    This session focused on the current status of neutrino event generators, in practical terms the tool through which ‘theory confronts experiment’. Comparisons of event generators, both in terms of input physics, and in terms of produced distributions, has been a staple of this conference series, and the activities in this area are summarized. In addition, we discuss the highest priorities for model development, discuss the changing needs of experimental users, and comment on challenges and needs for the road ahead.

  20. LGBT Roundtable Discussion: Meet-up and Mentoring Discussion

    NASA Astrophysics Data System (ADS)

    2014-03-01

    The LGBT+ Physicists group welcomes those who identify as gender sexual minorities, as LGBTQQIAAP+, or as allies to participate in a round-table discussion on mentoring physicists. The session will provide an opportunity to learn and discuss successful mentoring strategies at different career stages for physicists in all environments, including academia, industry, etc. Attendees are encouraged to attend a social event to follow the panel to continue to network. Allies are especially welcome at this event to learn how to support and mentor LGBT+ physicists.

  1. Promoting Colorectal Cancer Screening Discussion

    PubMed Central

    Christy, Shannon M.; Perkins, Susan M.; Tong, Yan; Krier, Connie; Champion, Victoria L.; Skinner, Celette Sugg; Springston, Jeffrey K.; Imperiale, Thomas F.; Rawl, Susan M.

    2013-01-01

    Background Provider recommendation is a predictor of colorectal cancer (CRC) screening. Purpose To compare the effects of two clinic-based interventions on patient–provider discussions about CRC screening. Design Two-group RCT with data collected at baseline and 1 week post-intervention. Participants/setting African-American patients that were non-adherent to CRC screening recommendations (n=693) with a primary care visit between 2008 and 2010 in one of 11 urban primary care clinics. Intervention Participants received either a computer-delivered tailored CRC screening intervention or a nontailored informational brochure about CRC screening immediately prior to their primary care visit. Main outcome measures Between-group differences in odds of having had a CRC screening discussion about a colon test, with and without adjusting for demographic, clinic, health literacy, health belief, and social support variables, were examined as predictors of a CRC screening discussion using logistic regression. Intervention effects on CRC screening test order by PCPs were examined using logistic regression. Analyses were conducted in 2011 and 2012. Results Compared to the brochure group, a greater proportions of those in the computer-delivered tailored intervention group reported having had a discussion with their provider about CRC screening (63% vs 48%, OR=1.81, p<0.001). Predictors of a discussion about CRC screening included computer group participation, younger age, reason for visit, being unmarried, colonoscopy self-efficacy, and family member/friend recommendation (all p-values <0.05). Conclusions The computer-delivered tailored intervention was more effective than a nontailored brochure at stimulating patient–provider discussions about CRC screening. Those who received the computer-delivered intervention also were more likely to have a CRC screening test (fecal occult blood test or colonoscopy) ordered by their PCP. Trial registration This study is registered at www

  2. Experts discuss how benchmarking improves the healthcare industry. Roundtable discussion.

    PubMed

    Capozzalo, G L; Hlywak, J W; Kenny, B; Krivenko, C A

    1994-09-01

    Healthcare Financial Management engaged four benchmarking experts in a discussion about benchmarking and its role in the healthcare industry. The experts agree that benchmarking by itself does not create change unless it is part of a larger continuous quality improvement program; that benchmarking works best when senior management supports it enthusiastically and when the "appropriate" people are involved; and that benchmarking, when implemented correctly, is one of the best tools available to help healthcare organizations improve their internal processes. PMID:10146069

  3. Body Art: A Panel Discussion.

    ERIC Educational Resources Information Center

    Surgenor, Peter; And Others

    1997-01-01

    Three camp directors discuss their policies regarding body art and body piercing. Only one director reported a strict policy prohibiting tattoos or body art based on standards that the camp portrays to families. However, all directors enforced policies prohibiting clothing or body art that mentions alcohol, tobacco, drug use, or inappropriate…

  4. A Philosophical Discussion of Representation.

    ERIC Educational Resources Information Center

    Moriarty, Sandra E.; Kenney, Keith

    One of the most basic theoretical areas in the study of visual communication and visual literacy is the nature of representation. Some of the important research in this area is reviewed in this paper, and a model of representation is developed that satisfies many of the philosophical concerns. The paper begins with a discussion on the relationship…

  5. A Study in Structured Discussion.

    ERIC Educational Resources Information Center

    Gutzmer, Willard Ernest

    This study tested the hypothesis that group interaction skill and useful learning occur in a discussion group which is academically structured. A class procedure involving a cognitive map, member skills and roles, and group etiquette was incorporated into a class ("Education and the Contemporary Scene," Fall Quarter, 1968) at the University of…

  6. What Is Effectiveness? Panel Discussion.

    ERIC Educational Resources Information Center

    Zigmond, Naomi

    Two papers are presented from a panel discussion moderated by Naomi Zigmond, who introduces the papers with a note on definitions and measures of intervention effectiveness. "Some Thoughts on Effective Intervention for Handicapped Preschoolers," by Phillip Strain, notes that special education researchers attempt to be efficient, economical,…

  7. Lively Discussions! Fostering Engaged Reading.

    ERIC Educational Resources Information Center

    Gambrell, Linda B., Ed.; Almasi, Janice F., Ed.

    Offering practical, classroom-based strategies teachers can use to promote literacy development, this book presents many examples of children engaging in discussion activities about narrative and informational text that emphasize collaborating, constructing meaning, and using these different types of texts to arrive at new understandings. Chapters…

  8. Black Psychologists Discuss Behavior Modification.

    ERIC Educational Resources Information Center

    Bardo, Harold R.; And Others

    The primary purpose of this paper is to discuss reasons why blacks should be concerned and actively involved with practices in behavior modification. The concern is that as these techniques are refined it becomes more important to be sure blacks should be involved at all levels of the application of these procedures when other blacks are subjects…

  9. Five Discussions on Postsecondary Education.

    ERIC Educational Resources Information Center

    Jobe, E. R., Ed.

    Topics discussed are: (1) student aid and access to postsecondary education (Jack L. Woodward); (2) values in athletics (Grant Dungee); (3) some considerations in planning for postsecondary education (Paul G. Orr); (4) the open university as a challenge for postsecondary education in Mississippi (Cleopatra D. Thompson); and (5) comprehensive…

  10. Linguistic Indexicality in Algebra Discussions

    ERIC Educational Resources Information Center

    Staats, Susan; Batteen, Chris

    2010-01-01

    In discussion-oriented classrooms, students create mathematical ideas through conversations that reflect growing collective knowledge. Linguistic forms known as indexicals assist in the analysis of this collective, negotiated understanding. Indexical words and phrases create meaning through reference to the physical, verbal and ideational context.…

  11. Another Discussion about Academic Corruption

    ERIC Educational Resources Information Center

    Changgeng, Li

    2007-01-01

    Academic corruption is a commonplace matter about which all people are clearly aware. However, people often overlook many hidden or latent manifestations of academic corruption. This article discusses eight of these manifestations: indiscriminate use of the academic team spirit, the proliferation of "word games," deliberate attacks on others to…

  12. Group discussion improves lie detection.

    PubMed

    Klein, Nadav; Epley, Nicholas

    2015-06-16

    Groups of individuals can sometimes make more accurate judgments than the average individual could make alone. We tested whether this group advantage extends to lie detection, an exceptionally challenging judgment with accuracy rates rarely exceeding chance. In four experiments, we find that groups are consistently more accurate than individuals in distinguishing truths from lies, an effect that comes primarily from an increased ability to correctly identify when a person is lying. These experiments demonstrate that the group advantage in lie detection comes through the process of group discussion, and is not a product of aggregating individual opinions (a "wisdom-of-crowds" effect) or of altering response biases (such as reducing the "truth bias"). Interventions to improve lie detection typically focus on improving individual judgment, a costly and generally ineffective endeavor. Our findings suggest a cheap and simple synergistic approach of enabling group discussion before rendering a judgment. PMID:26015581

  13. Group discussion improves lie detection

    PubMed Central

    Klein, Nadav; Epley, Nicholas

    2015-01-01

    Groups of individuals can sometimes make more accurate judgments than the average individual could make alone. We tested whether this group advantage extends to lie detection, an exceptionally challenging judgment with accuracy rates rarely exceeding chance. In four experiments, we find that groups are consistently more accurate than individuals in distinguishing truths from lies, an effect that comes primarily from an increased ability to correctly identify when a person is lying. These experiments demonstrate that the group advantage in lie detection comes through the process of group discussion, and is not a product of aggregating individual opinions (a “wisdom-of-crowds” effect) or of altering response biases (such as reducing the “truth bias”). Interventions to improve lie detection typically focus on improving individual judgment, a costly and generally ineffective endeavor. Our findings suggest a cheap and simple synergistic approach of enabling group discussion before rendering a judgment. PMID:26015581

  14. From Bretonneau to therapeutic antibodies, from specificity to specific remedies, Saint-Cyr-Sur-Loire, France, November 19, 2012

    PubMed Central

    Marchand, Claire; Nouat, Romaric; Watier, Hervé

    2013-01-01

    Held on November 19, 2012 in Saint-Cyr-sur-Loire, France, the symposium “From Bretonneau to therapeutic antibodies, from specificity to specific remedies” focused on the historical development of antibodies as therapeutics, with an emphasis on the seminal work of the French physician Pierre-Fidèle Bretonneau (1778–1862). The morning session was devoted to discussion of the evolution of the concept of specificity in medicine, which started with an epistemological definition. The contributions of Bretonneau to the emergence of the concept of specificity, notably with his studies on diphtheria, and the subsequent development of antidiphtheric serotherapy in Europe during the period 1894–1898 were then presented in detail. The afternoon session began with a presentation on the role of French physiologists during the years 1860–1890 in establishing the basic concepts of specific immunity and the principles of serotherapy. The history of antivenom serotherapy, particularly its discovery by Césaire Phisalix, and the development of antilymphocyte globulins as successful transplantation drugs were then discussed. The symposium ended with the inauguration of a stele representing Bretonneau, who lived in Saint-Cyr-sur-Loire and died 150 y ago. PMID:23924799

  15. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7... LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the southernmost extremity of Fossil Point at longitude 120°43.5′ W. to the seaward extremity of Whaler...

  16. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7... LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the southernmost extremity of Fossil Point at longitude 120°43.5′ W. to the seaward extremity of Whaler...

  17. Panel Discussion v: Neutrino Physics

    NASA Astrophysics Data System (ADS)

    Obraztsov, Vladimir; Konaka, Akira; Ikeda, Motoyasu; Jediny, Filip; Shirokov, Evgeny; Kalekin, Oleg; Palomares-Ruiz, Sergio

    2015-06-01

    Questions to discuss: * Can sidereal time analysis of the long time neutrino observations give information about the galaxy distribution in the Local Universe? * How well do we need to know the PMNS matrix elements? * Is the existence of MSW effect proved experimentally? * Are there new species of neutrino (e.g. the sterile one)? * What are other most important problems in neutrino physics (CP-violation)? * Can sidereal time analysis of the long time neutrino observations give information about the galaxy distribution in the Local Universe? * Perspectives of existing and future neutrino experiments (LNBF, LAGUNA, ICARUS, SHIP ...)

  18. Lignes directrices simplifiées sur les lipides

    PubMed Central

    Allan, G. Michael; Lindblad, Adrienne J.; Comeau, Ann; Coppola, John; Hudson, Brianne; Mannarino, Marco; McMinis, Cindy; Padwal, Raj; Schelstraete, Christine; Zarnke, Kelly; Garrison, Scott; Cotton, Candra; Korownyk, Christina; McCormack, James; Nickel, Sharon; Kolber, Michael R.

    2015-01-01

    Résumé Objectif Produire un guide de pratique clinique comportant une approche simplifiée à la prévention primaire des maladies cardiovasculaires (MCV), en insistant sur l’estimation du risque de MCV et la prise en charge des profils lipidiques à l’intention des cliniciens de soins primaires et leurs équipes; nous avons recherché la contribution de professionnels des soins primaires qui n’avaient que peu ou pas de conflits d’intérêts et nous nous sommes concentrés sur les données probantes de la plus haute qualité accessibles. Méthodes Neuf professionnels de la santé (4 médecins de famille, 2 internistes, 1 infirmière praticienne, 1 infirmière autorisée et 1 pharmacienne) et 1 membre non votant (pharmacienne gestionnaire de projet) formaient le comité principal appelé le Lipid Pathway Committee (le comité). La sélection des membres s’est fondée sur la profession, le milieu de pratique et son emplacement. Les membres ont divulgué tous leurs conflits d’intérêts potentiels ou réels. Le processus d’élaboration des lignes directrices était itératif et s’appuyait sur des affichages en ligne, une révision détaillée des données probantes, des réunions par téléphone et en ligne. Le comité a cerné 12 questions prioritaires à répondre. Le groupe de révision des données probantes a répondu à ces questions. À la suite d’un examen des réponses, les principales recommandations ont été formulées par consensus du comité. Nous avons produit une ébauche des lignes directrices qui a ensuite été peaufinée, distribuée à un groupe de cliniciens (médecins de famille, autres spécialistes, pharmaciens, infirmières et infirmières praticiennes) et à des patients pour obtenir de la rétroaction, la réviser en conséquence et le comité l’a ensuite finalisée. Recommandations Des recommandations sont présentées concernant le dépistage et les analyses, les évaluations du risque, le suivi, de même que le r

  19. Structure of thermotoga maritima stationary phase survival protein SurE : a novel acid phosphatase.

    SciTech Connect

    Zhang, R.-G; Skarina, T.; Katz, J. E.; Khachatryan, A; Vyas, S.; Arrowsmith, C. H.; Clarke, S.; Edwards, A.; Joachimiak, A.; Savchenko, A.; Biosciences Division; Univ. of Toronto; Univ. of California; Clinical Genomics Centre /Proteomics, Univ. Health Network

    2001-11-01

    Background: The rpoS, nlpD, pcm, and surE genes are among many whose expression is induced during the stationary phase of bacterial growth. rpoS codes for the stationary-phase RNA polymerase {sigma} subunit, and nlpD codes for a lipoprotein. The pcm gene product repairs damaged proteins by converting the atypical isoaspartyl residues back to L-aspartyls. The physiological and biochemical functions of surE are unknown, but its importance in stress is supported by the duplication of the surE gene in E. coli subjected to high-temperature growth. The pcm and surE genes are highly conserved in bacteria, archaea, and plants. Results: The structure of SurE from Thermotoga maritima was determined at 2.0 Angstroms. The SurE monomer is composed of two domains; a conserved N-terminal domain, a Rossman fold, and a C-terminal oligomerization domain, a new fold. Monomers form a dimer that assembles into a tetramer. Biochemical analysis suggests that SurE is an acid phosphatase, with an optimum pH of 5.5-6.2. The active site was identified in the N-terminal domain through analysis of conserved residues. Structure-based site-directed point mutations abolished phosphatase activity. T. maritima SurE intra- and intersubunit salt bridges were identified that may explain the SurE thermostability. Conclusions: The structure of SurE provided information about the protein's fold, oligomeric state, and active site. The protein possessed magnesium-dependent acid phosphatase activity, but the physiologically relevant substrate(s) remains to be identified. The importance of three of the assigned active site residues in catalysis was confirmed by site-directed mutagenesis.

  20. Science leaders discuss budget crunch

    NASA Astrophysics Data System (ADS)

    Although funding for research fared relatively well in the budget proposed by the Reagan Administration for fiscal year (FY) 1987, leaders of the science community should expect lean times ahead for federal funding and should plan accordingly. This was the message delivered February 26-27, 1986, to nearly 400 participants in a conference at the National Academy of Sciences (NAS) in Washington, D.C.Leaders and policymakers from all segments of the research establishment were invited to attend the 2-day conference, which was sponsored by the Government-University-Industry Research Roundtable, an independent group associated with NAS, the National Academy of Engineering, and the Institute of Medicine. Discussions at the conference revolved around the question “What research strategies best serve the national interest in a period of budgetary stress?” After hearing perspectives from representatives from the Administration, industry, federal agencies, universities, and a federal laboratory, participants were divided into seven working groups. Each group was assigned a topic of discussion, such as “Management at the Campus Level,” “The Relative Roles of Federal Laboratories and Outside Research Institutions,” and “Possible Non-Federal Sources of Support: States, Industry, and Foundations.” On the second day of the conference, the working group chairmen reported back to the conference at large.

  1. Lesbians discuss beauty and aging.

    PubMed

    Thompson, K M; Brown, N; Cassidy, J; Gentry, J H

    1999-01-01

    ABSTRACT Two conversations with three aging lesbians are presented to identify and explore different definitions of beauty and how these definitions change and are influenced by age. The three women interviewed believe beauty is more than skin deep, yet they differ regarding specific components of beauty. Two believe that their definition of beauty has changed as they age and one believes that her definition has remained basically unchanged through the years. Topics of discussion include: beauty role models, the impact of the American beauty standard on their self-esteem, and what they look for in potential partners. Through these women's diverse opinions on how beauty is defined and experienced by older lesbians, we see that there is no one perspective representing all older women. PMID:24786423

  2. To discuss illicit nuclear trafficking

    SciTech Connect

    Balatsky, Galya I; Severe, William R; Wallace, Richard K

    2010-01-01

    The Illicit nuclear trafficking panel was conducted at the 4th Annual INMM workshop on Reducing the Risk from Radioactive and Nuclear Materials on February 2-3, 2010 in Washington DC. While the workshop occurred prior to the Nuclear Security Summit, April 12-13 2010 in Washington DC, some of the summit issues were raised during the workshop. The Communique of the Washington Nuclear Security Summit stated that 'Nuclear terrorism is one of the most challenging threats to international security, and strong nuclear security measures are the most effective means to prevent terrorists, criminals, or other unauthorized actors from acquiring nuclear materials.' The Illicit Trafficking panel is one means to strengthen nuclear security and cooperation at bilateral, regional and multilateral levels. Such a panel promotes nuclear security culture through technology development, human resources development, education and training. It is a tool which stresses the importance of international cooperation and coordination of assistance to improve efforts to prevent and respond to incidents of illicit nuclear trafficking. Illicit trafficking panel included representatives from US government, an international organization (IAEA), private industry and a non-governmental organization to discuss illicit nuclear trafficking issues. The focus of discussions was on best practices and challenges for addressing illicit nuclear trafficking. Terrorism connection. Workshop discussions pointed out the identification of terrorist connections with several trafficking incidents. Several trafficking cases involved real buyers (as opposed to undercover law enforcement agents) and there have been reports identifying individuals associated with terrorist organizations as prospective plutonium buyers. Some specific groups have been identified that consistently search for materials to buy on the black market, but no criminal groups were identified that specialize in nuclear materials or isotope smuggling

  3. Discussion on selected symbiotic stars

    NASA Technical Reports Server (NTRS)

    Viotti, Roberto; Hack, Margherita

    1993-01-01

    Because of its large variety of aspects, the symbiotic phenomenon is not very suitable for a statistical treatment. It is also not clear whether symbiotic stars really represent a homogeneous group of astrophysical objects or a collection of objects of different natures but showing similar phenomena. However we are especially interested in the symbiotic phenomenon, i.e., in those physical processes occurring in the atmosphere of each individual object and in their time dependence. Such a research can be performed through the detailed analysis of individual objects. This study should be done for a time long enough to cover all the different phases of their activity, in all the spectral ranges. Since the typical time scale of the symbiotic phenomena is up to several years and decades, this represents a problem since, for instance, making astronomy outside the visual region is a quite new field of research. It was a fortunate case that a few symbiotic stars (Z And, AG Dra, CH Cyg, AX Per, and PU Vul) had undergone remarkable light variations (or 'outbursts') in recent years, which could have been followed in the space ultraviolet with IUE, and simultaneously in the optical and IR with ground-based telescopes. But, in general, the time coverage of most of the symbiotic objects is too short to have a complete picture of their behavior. In this regard, one should recall Mayall's remark about the light curve of Z And: 'Z Andromedae is another variable that shows it will require several hundred years of observations before a good analysis can be made of its variations'. This pessimistic remark should be considered as a note of caution for those involved in the interpretation of the observations. We shall discuss a number of individual symbiotic stars for which the amount of observational data is large enough to draw a rather complete picture of their general behavior and to make consistent models. We shall especially illustrate the necessary steps toward an empirical model

  4. Muscle coordination: the discussion continues

    PubMed

    Prilutsky

    2000-01-01

    In this response, the major criticisms of the target article are addressed. Terminology from the target article that may have caused some confusion is clarified. In particular, the tasks that have the basic features of muscle coordination, as identified in the target article, have been limited in scope. A new metabolic optimization criterion suggested by Alexander (2000) is examined for its ability to predict muscle coordination in walking. Issues concerning the validation of muscle force predictions, the rules of muscle coordination, and the role of directional constraints in coordination of two-joint muscles are discussed. It is shown in particular that even in one-joint systems, the forces predicted by the criterion of Crowninshield and Brand (1981) depend upon the muscle moment arms and the physiological cross-sectional areas in much more complex ways than either previously assumed in the target article, or incorrectly derived by Herzog and Ait-Haddou (2000). It is concluded that the criterion of Crowninshield and Brand qualitatively predicts the basic coordination features of the major one- and two-joint muscles in a number of highly skilled, repetitive motor tasks performed by humans under predictable conditions and little demands on stability and accuracy. A possible functional significance of such muscle coordination may be the minimization of perceived effort, muscle fatigue, and/or energy expenditure. PMID:10675817

  5. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury

    PubMed Central

    Nicholson, James D.; Guo, Yan; Bernstein, Steven L.

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role. PMID:27560494

  6. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury.

    PubMed

    Nicholson, James D; Guo, Yan; Bernstein, Steven L

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role. PMID:27560494

  7. [Marine algae of Baja California Sur, Mexico: nutritional value].

    PubMed

    Carrillo Domínguez, Silvia; Casas Valdez, Margarita; Ramos Ramos, Felipe; Pérez-Gil, Fernando; Sánchez Rodríguez, Ignacio

    2002-12-01

    The Baja California Peninsula is one of the richest regions of seaweed resources in México. The objective of this study was to determine the chemical composition of some marine algae species of Baja California Sur, with an economical potential due to their abundance and distribution, and to promote their use as food for human consumption and animal feeding. The algae studied were Green (Ulva spp., Enteromorpha intestinalis, Caulerpa sertularoides, Bryopsis hypnoides), Red (Laurencia johnstonii, Spyridia filamentosa, Hypnea valentiae) and Brown (Sargassum herporizum, S. sinicola, Padina durvillaei, Hydroclathrus clathrathus, Colpomenia sinuosa). The algae were dried and ground before analysis. In general, the results showed that algae had a protein level less than 11%, except L. johnstonii with 18% and low energy content. The ether extract content was lower than 1%. However, the algae were a good source of carbohydrates and inorganic matter. PMID:12868282

  8. ``Astrophysique sur Mesure'', E-learning in Astronomy and Astrophysics

    NASA Astrophysics Data System (ADS)

    Mosser, Benoît; Delsanti, Audrey; Guillaume, Damien; Balança, Christian; Balkowski, Chantal

    2011-06-01

    ``Astrophysique sur Mesure'' (astrophysics made-to-measure) is a set of e-learning programmes started 4 years ago at the Paris Observatory. In order to deliver attractive and efficient programmes, we have added many multimedia tools to usual lectures: animations, Java applets. The programmes are presented on two different platforms. The first one offers the content of all the lectures in free access. A second platform with restricted access is provided to registered students taking part in the e-learning program and benefiting from the help of tutors. The development of these programs helps to increase the sphere of influence of astronomy taught at the Paris Observatory, hence to increase the presence of astronomy in various degree courses. Instead of teaching classical astronomy lectures to a happy few, we can bring astronomy and astrophysics to a wider audience.

  9. Enquete sur les aspects toxicologiques de la phytotherapie utilisee par un herboriste à Fes, Maroc

    PubMed Central

    Zeggwagh, Ali Amine; Lahlou, Younes; Bousliman, Yassir

    2013-01-01

    Introduction Dans le but d'étudier l'aspect toxicologique des plantes médicinales utilisées en médecine traditionnelle, une étude ethnobotanique a été réalisée à la ville de Fès au centre du Maroc. Méthodes Ont été inclus dans l'étude tous les patients ayant bénéficié d'une prescription par l'herboriste de plantes à visée thérapeutique. La discussion de nos résultats s'est faite sur la base d'une revue de la littérature avec identification des principales plantes toxiques utilisées en phytothérapie au Maroc. L'approche bibliographique a permis de compléter les informations. Résultats L'âge moyen des patients traités par des plantes (38 femmes, 32 hommes) était de 35 ± 18 ans. L'enquête ethnobotanique à révélé que la majorité des plantes médicinales étaient utilisées contre les affections urinaires (21%), suivi des maladies de l'appareil digestif (19.6%) et des maladies rhumatologiques (18.2%). Le nombre de plantes prescrits par l'herboriste a été de 53 dont 5 sont potentiellement toxiques. L'identification taxonomique des plantes prescrites a recensé 30 familles dont les plus représentées sont les Lamiaceae (23.33%), les Apiaceae (13,33%) et les Asteraceae (10%). La prescription des plantes considérées comme toxiques a concerné 7,1% des consultants traités par les plantes médicinales. Aucune complication inhérente aux plantes prescrites n'a été déplorée. Conclusion Malgré les résultats encourageants de notre enquête sur le compte de la phytothérapie, la pratique de la phytothérapie est laissée à la vulgarisation et à l'oubli scientifique, législatif et universitaire. PMID:23734270

  10. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2014-10-01 2014-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  11. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2012-10-01 2012-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  12. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2011-10-01 2011-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  13. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2013-10-01 2013-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  14. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2010-10-01 2010-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  15. Modelisations des effets de surface sur les jets horizontaux subsoniques d'hydrogene et de methane

    NASA Astrophysics Data System (ADS)

    Gomez, Luis Fernando

    Le developpement des codes et de normes bases sur une methodologie scientifique requiert la capacite de predire l'etendue inflammable de deversements gazeux d'hydrogene sous differentes conditions. Des etudes anterieures ont deja etabli des modeles bases sur les lois de conservation de la mecanique des fluides basees sur des correlations experimentales qui permettent de predire la decroissance de la concentration et de la vitesse d'un gaz le long de l'axe d'un jet libre vertical. Cette etude s'interesse aux effets de proximite a une surface horizontale parallele sur un jet turbulent. Nous nous interessons a son impact sur l'etendue du champ de la concentration et sur l'enveloppe inflammable en particulier. Cette etude est comparative : l'hydrogene est compare au methane. Ceci permet de degager l'influence des effets de difference de la densite sur le comportement du jet, et de comparer le comportement de l'hydrogene aux correlations experimentales, qui ont ete essentiellement etablies pour le methane. Un modele decrivant l'evolution spatio-temporelle du champ de concentration du gaz dilue est propose, base sur la mecanique des fluides computationnelle. Cette approche permet de varier systematiquement les conditions aux frontieres (proximite du jet a la surface, par exemple) et de connaitre en detail les proprietes de l'ecoulement. Le modele est implemente dans le code de simulations par volumes finis de FLUENT. Les resultats des simulations sont compares avec les lois de similitudes decoulant de la theorie des jets d'ecoulements turbulents libres ainsi qu'avec les resultats experimentaux disponibles. L'effet de la difference des masses molaires des constituantes du jet et des constituantes du milieu de dispersion est egalement etudie dans le contexte du comportement d'echelle de la region developpee du jet.

  16. Carcinome hépatocellulaire non fibrolamellaire sur foie sain

    PubMed Central

    Bouomrani, Salem; Kilani, Ichrak; Nouma, Hanène; Slama, Alaeddine; Beji, Maher

    2014-01-01

    Le carcinome hépatocellulaire (CHC) survient le plus souvent sur foie de cirrhose. Sa survenue sur un foie sain est exceptionnelle et pose un véritable défit diagnostique pour le clinicien. Nous rapportons l'observation d'un patient de 53 ans, sans antécédents pathologiques notables qui fût admis pour exploration d'une douleur de l'hypochondre droit évoluant depuis quelques mois avec une exacerbation récente, associée à un amaigrissement important et une altération de l’état général. L'examen clinique notait une hépatomégalie ferme et douloureuse. L’échographie abdominale montrait une masse hétérogène du secteur latéral droit du foie faisant 10 cm de grand axe. La TDM abdominale montrait une masse tissulaire, hétérogène, à vascularisation artérielle importante, mesurant 10 cm de diamètre et occupant le secteur latéral droit du foie. Cette tumeur comprime la branche portale droite sans signes d'extension. Il n'y avait pas d'adénopathie ni d’épanchement intra abdominal. La ponction biopsique écho-guidée avait conclu à un CHC non fibrolamellaire. Le bilan biologique, en particulier les transaminases, le taux de prothrombine, l’électrophorèse des protéines sanguine et l'alpha foeto-protéine, était sans anomalies. Les sérologies de l'hépatites virales B et C ainsi que la recherche des auto anticorps spécifiques des hépatites auto immunes et le bilan cuprique étaient aussi négatives. Vue l’âge, le stade avancé de la tumeur et l'altération de l’état général la conduite thérapeutique était de s'abstenir. PMID:25419293

  17. Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

    PubMed Central

    Kaduwal, Saluja; Jeong, Woo-Jeong; Park, Jong-Chan; Lee, Kug Hwa; Lee, Young-Mi; Jeon, Soung-Hoo; Lim, Yong-Beom; Min, Do Sik; Choi, Kang-Yell

    2015-01-01

    Sur8 (also known as Shoc2) is a Ras-Raf scaffold protein that modulates signaling through extracellular signal-regulated kinase (ERK) pathway. Although Sur8 has been shown to be a scaffold protein of the Ras-ERK pathway, its interaction with other signaling pathways and its involvement in tumor malignancy has not been reported. We identified that Sur8 interacts with the p110α subunit of phosphatidylinositol 3-kinase (PI3K), as well as with Ras and Raf, and these interactions are increased in an epidermal growth factor (EGF)- and oncogenic Ras-dependent manner. Sur8 regulates cell migration and invasion via activation of Rac and matrix metalloproteinases (MMPs). Interestingly, using inhibitors of MEK and PI3K we found Sur8 mediates these cellular behaviors predominantly through PI3K pathway. We further found that human metastatic melanoma tissues had higher Sur8 content followed by activations of Akt, ERK, and Rac. Lentivirus-mediated Sur8-knockdown attenuated metastatic potential of highly invasive B16-F10 melanoma cells indicating the role of Sur8 in melanoma metastasis. This is the first report to identify the role of scaffold protein Sur8 in regulating cell motility, invasion, and metastasis through activation of both ERK and PI3K pathways. PMID:26384305

  18. Discussion, Schooling, and the Struggle for Democracy.

    ERIC Educational Resources Information Center

    Preskill, Stephen

    1997-01-01

    Argues that because democracy, education, and discussion are interrelated and seek to promote human growth, ways must be found to involve children and adults in frequent discussions. Focuses on democratic education, including the barriers, functions of discussion, and dispositional ideals for classroom members. Concludes that discussion is an…

  19. Increasing Moral Reasoning Skills through Online Discussions

    ERIC Educational Resources Information Center

    Cain, Jeff; Smith, Doug

    2009-01-01

    This study examined the effects that online asynchronous dilemma discussions have on moral reasoning scores of pharmacy students. In contrast to face-to-face group discussions, asynchronous threaded discussions afford all participants time to reflect and respond during discussions. Anonymity features may lessen inhibitions in responding critically…

  20. Traumatismes Oculaires par Petards: Bilan sur Trois Annees

    PubMed Central

    Zouaoui-Kesraoui, N.; Derdour, A.

    2009-01-01

    Summary Les accidents dus aux pétards sont des accidents graves. Leur recrudescence ces dernières années en Algérie, essentiellement durant les fêtes du Mawlid Ennabaoui (fête de la naissance du prophète), mérite à notre sens d'entreprendre des bilans exhaustifs dont celui-ci dans le but d'une sensibilisation de toutes les compétences concernées. Nous avons réuni sur trois années consécutives (2002, 2003, 2004) 60 dossiers de malades ayant subi des accidents oculaires par pétards. Nos patients sont répartis en 42 consultations pour blessures légères et 18 hospitalisations pour blessures graves. Parmi ces derniers, neuf ont présenté des complications et séquelles graves (cinq cas de cécité par atrophie du globe oculaire, trois cas de cécité cornéenne et un cas de cécité par trou maculaire). Dans tous ces cas l'incapacité permanente partielle est au minimum de 30%. Au vu de ces données nous proposons des mesures d'éducation sanitaire et une sensibilisation du grand public aux traumatismes oculaires, par le biais de mé dias appropriés: radio, télévision, affiches. PMID:21991157

  1. Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen.

    PubMed

    Mohammed Abdul, Khaja Shameem; Jovanović, Sofija; Sukhodub, Andriy; Du, Qingyou; Jovanović, Aleksandar

    2014-11-01

    The effects of hypoxia on gene expression have been vigorously studied, but possible effects of small changes in oxygen tension have never been addressed. SUR2A is an atypical ABC protein serving as a regulatory subunit of sarcolemmal ATP-sensitive K(+) (KATP) channels. Up-regulation of SUR2A is associated with cardioprotection and improved physical endurance. Here, we have found that a 24h-long exposure to slightly decreased ambient fractional concentration of oxygen (20% oxygen), which is an equivalent to oxygen tension at 350m above sea level, significantly increased levels of SUR2A in the heart despite that this drop of oxygen did not affect levels of O2, CO2 and hematocrit in the blood or myocardial levels of ATP, lactate and NAD/NADH/NAD(+). Hearts from mice exposed to 20% oxygen were significantly more resistant to ischaemia-reperfusion when compared to control ones. Decrease in fractional oxygen concentration of just 0.9% was associated with phosphorylation of ERK1/2, but not Akt, which was essential for up-regulation of SUR2A. These findings indicate that a small drop in oxygen tension up-regulates SUR2A in the heart by activating ERK signaling pathway. This is the first report to suggest that a minimal change in oxygen tension could have a profound signaling effect. PMID:25064694

  2. Discussing Diabetes with Your Healthcare Provider

    MedlinePlus

    ... of this page please turn Javascript on. Feature: Diabetes Discussing Diabetes with Your Healthcare Provider Past Issues / Fall 2009 Table of Contents Diabetes Medicines—Always Discuss Them with Your Healthcare Provider ...

  3. Video 7 of 14: Classroom Discussion

    NASA Video Gallery

    This video segment documents the follow-up discussion, in which students discuss the results of their test flights. The session demonstrates how the teacher uses the inquiry method to evaluate stud...

  4. Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH.

    PubMed

    Mohammed Abdul, Khaja Shameem; Jovanović, Sofija; Du, Qingyou; Sukhodub, Andriy; Jovanović, Aleksandar

    2015-05-01

    High-altitude residents have lower mortality rates for ischaemic heart disease and this is ascribed to cardiac gene remodelling by chronic hypoxia. SUR2A is a cardioprotective ABC protein serving as a subunit of sarcolemmal ATP-sensitive K(+) channels. The purpose of this study was to determine whether SUR2A is regulated by mild hypoxia in vivo and to elucidate the underlying mechanism. Mice were exposed to either 21% (control) or 18% (mild hypoxia) oxygen for 24h. Exposure to 18% oxygen did not affect partial pressure of O(2) (PO(2)) and CO(2) (PCO(2)) in the blood, haematocrit or level of ATP in the heart. However, hypoxia increased myocardial lactate dehydrogenase (LDH) and lactate as well as NAD(+) without affecting total NAD. SUR2A levels were significantly increased as well as myocardial resistance to ischaemia-reperfusion. Exposure to 18% oxygen did not phosphorylate extracellular signal regulated kinases (ERK1/2) or AMP activated protein kinase (AMPK), but it phosphorylated protein kinase B (Akt). An inhibitor of phosphoinositide 3-kinases (PI3K), LY294002 (0.2mg/mouse), abolished all observed effects of hypoxia. LDH inhibitors, galloflavin (50 μM) and sodium oxamate (80 mM) significantly decreased levels of SUR2A in heart embryonic H9c2 cells, while inactive mutant LDH form, gly193-M-LDH increased cellular sensitivity towards stress induced by 2,4-dinitrophenol (10mM). Treatment of H9c2 cells with sodium lactate (30 mM) increased intracellular lactate, but did not affect LDH activity or SUR2A levels. We conclude that PI3K/Akt signalling pathway and LDH play a crucial role in increase of cardiac SUR2A induced by in vivo exposure to 18% oxygen. PMID:25576887

  5. USENET Discussion Groups in Political Science Courses.

    ERIC Educational Resources Information Center

    Bailey, Martha

    1995-01-01

    Considers the applications and limitations of supplementing political science instruction with USENET discussion groups. Maintains that the engaging and topical nature of the discussion groups can enhance traditional course materials. Notes, however, that USENET comments often are not indicative of the general public. Briefly discusses reference…

  6. Discussion Technique: The Twice-Around

    ERIC Educational Resources Information Center

    Andersen, Kent

    2013-01-01

    In this article, the author offers a discussion technique: the twice-around. A variant on the circular response discussion, the twice-around engages students by beginning with students' questions, ensuring equal time for all participants and inviting discussants to build on previous contributions. In the twice-around, participants sit in a circle,…

  7. Deliberative discussion as an innovative teaching strategy.

    PubMed

    Goodin, Heather Janiszewski; Stein, David

    2008-06-01

    The discussion method is a teaching strategy commonly used by nurse educators in a variety of educational settings. However, relatively unknown to nursing education is a unique discussion teaching strategy: the deliberative discussion method. The deliberative discussion method was developed by the National Issues Forums Institute for the sole purpose of creating a means to engage people and communities to dialogue with one another. In essence, a deliberative discussion is a shared inquiry that asks participants to talk through and weigh the costs and consequences of a variety of options of solutions to a public problem. At the heart of deliberation is the group's willingness to work through the conflicts, to accept the consequences of their choices, and to establish grounds for action. Deliberative discussion offers an innovative approach to health care or other nursing issues in the classroom. PMID:18557315

  8. A discussion of dynamic stability measurement techniques

    NASA Technical Reports Server (NTRS)

    Johnson, W.

    1975-01-01

    Techniques for the measurement of the dynamic stability of linear systems are discussed. Particular attention is given to an analysis of the errors in the procedures, and to methods for calculating the system damping from the data. The techniques discussed include: transient decay, moving block analysis, spectral analysis, random decrement signatures, transfer function analysis, and parameter identification methods. The special problems of rotorcraft dynamic stability testing are discussed.

  9. 33 CFR 240.5 - Discussion.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Discussion. 240.5 Section 240.5 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE GENERAL CREDIT FOR FLOOD CONTROL § 240.5 Discussion. Discussion of this legislation is contained in the Conference Report, H.R. Rpt. No. 99-1013,...

  10. A Preliminary Study of the Effects of SurAsleep on Relieving Symptoms of Sleep Disorders

    PubMed Central

    Xie, Qingwen; Zhou, Tian; Yen, Lawrence; Song, Andrew; Shariff, Mina; Nguyen, Tuong; Rao, Jianyu; Shi, Rong

    2015-01-01

    Sleep disorder is a common condition in the general population. Conventional sedative-hypnotic drug therapy may not be appropriate for many patients suffering from only mild-to-moderate sleep disorders. SurAsleep, a nutritional supplement that has been used by patients with sleep disorders in the United States, shows promising effects in improving sleep disorders and enhancing sleep quality. However, double-blinded, randomized and controlled studies have not been performed to determine the efficacy of the supplement. We conducted this study on individuals suffering from mild-to-moderate sleep disorders in Shanghai, China. In this study, we randomly assigned 100 participants over the age of 50 years old with symptoms of sleep disorders to a 12-week treatment with either SurAsleep or placebo. The results were measured by a self-administrated questionnaire on changes in symptoms, which covered 3 phases of sleep: the falling-asleep stage, the sleeping stage and the waking-up stage. We also measured the changes after the 12-week intervention using the Pittsburgh Sleep Quality Index (PSQI), including 7 dimensions of sleeping. All symptoms, dimension-specific PSQI scores and total PSQI scores showed significant improvement after using SurAsleep. In this study, SurAsleep has shown potent effects in relieving somnipathy-related symptoms and improving sleep quality in sleep disorder patients. PMID:26199580

  11. Seafloor Rocks and Sediments of the Continental Shelf From Monterey Bay to Point Sur, California

    USGS Publications Warehouse

    Eittreim, Stephen L.; Anima, Roberto J.; Stevenson, Andrew J.; Wong, Florence L.

    2000-01-01

    Introduction Acoustic swath mapping of the greater Monterey Bay area continental shelf from Point Ano Nuevo to Point Sur reveals complex patterns of rock outcrops on the shelf, and coarse sand bodies that occur in distinct depressions on the inner and mid-shelves. This publication portrays the seafloor components in a 36- by 48-inch map sheet at 1:100,000 scale.

  12. The Classroom as Big Sur: Notes on the Liaison Between Evaluation and Professional Growth

    ERIC Educational Resources Information Center

    Sneeden, Ralph

    2013-01-01

    Bill Frisell's new album ("Big Sur") was heralded with a short documentary about its impulse and inception: Frisell's retreat to an isolated coastal ranch in Central California. In the video, he describes the influence of the place, the dramatic and evocative landscape, and how it ultimately became the subject and theme for the…

  13. Reflections on "Petit Battement sur le Cou de Pied": Is It Still Relevant?

    ERIC Educational Resources Information Center

    Paskevska, Anna

    2007-01-01

    This article presents multiple perspectives of "petit battement sur le cou de pied". These perspectives include historical, biomechanical, and pedagogic points of view. The article offers useful information for ballet specialists and applied research studies aimed at ballet pedagogy. (Contains 2 tables and 5 figures.)

  14. Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study.

    PubMed

    Proks, Peter; de Wet, Heidi; Ashcroft, Frances M

    2014-11-01

    Sulfonylureas, which stimulate insulin secretion from pancreatic β-cells, are widely used to treat both type 2 diabetes and neonatal diabetes. These drugs mediate their effects by binding to the sulfonylurea receptor subunit (SUR) of the ATP-sensitive K(+) (KATP) channel and inducing channel closure. The mechanism of channel inhibition is unusually complex. First, sulfonylureas act as partial antagonists of channel activity, and second, their effect is modulated by MgADP. We analyzed the molecular basis of the interactions between the sulfonylurea gliclazide and Mg-nucleotides on β-cell and cardiac types of KATP channel (Kir6.2/SUR1 and Kir6.2/SUR2A, respectively) heterologously expressed in Xenopus laevis oocytes. The SUR2A-Y1206S mutation was used to confer gliclazide sensitivity on SUR2A. We found that both MgATP and MgADP increased gliclazide inhibition of Kir6.2/SUR1 channels and reduced inhibition of Kir6.2/SUR2A-Y1206S. The latter effect can be attributed to stabilization of the cardiac channel open state by Mg-nucleotides. Using a Kir6.2 mutation that renders the KATP channel insensitive to nucleotide inhibition (Kir6.2-G334D), we showed that gliclazide abolishes the stimulatory effects of MgADP and MgATP on β-cell KATP channels. Detailed analysis suggests that the drug both reduces nucleotide binding to SUR1 and impairs the efficacy with which nucleotide binding is translated into pore opening. Mutation of one (or both) of the Walker A lysines in the catalytic site of the nucleotide-binding domains of SUR1 may have a similar effect to gliclazide on MgADP binding and transduction, but it does not appear to impair MgATP binding. Our results have implications for the therapeutic use of sulfonylureas. PMID:25348414

  15. Discussion paper on energy grant alternatives

    SciTech Connect

    Humphrey, B.; Clifford, D.; Gunnison, F.; Tatar, J.

    1981-07-01

    The federal grant-in-aid system now consists of three general types of grants: categorical grants; block grants; and general revenue sharing. These are discussed and compared. The types of complications that may arise from implementation of these grants proposals are discussed. Some proposals for the possible consolidation of programs that the Department of Energy offices now administer are summarized. (MCW)

  16. Informal Discussions in Substance Abuse Treatment Sessions

    PubMed Central

    Martino, Steve; Ball, Samuel A.; Nich, Charla; Frankforter, Tami L.; Carroll, Kathleen M.

    2009-01-01

    This study evaluated the extent to which counselors initiated informal discussions (i.e., general discussions and self-disclosures about matters unrelated to treatment) with their clients during treatment sessions within two National Institute on Drug Abuse Clinical Trial Network protocols involving adaptations of motivational interviewing (MI). Sixty counselors across the two protocols had 736 sessions independently rated for counselor treatment fidelity and the occurrence of informal discussions. The results showed that 88% of the counselors initiated informal discussions in their sessions and that the majority of these discussions involved counselors sharing personal information or experiences they had in common with their clients. The major finding was that counselor training in MI was associated with significantly less informal discussion across sessions. A higher frequency of informal discussion was related to less counselor MI proficiency and less in-session change in client motivation, though unrelated to client program retention and substance use outcomes. The findings suggest that while some informal discussion may help build an alliance between counselors and clients, too much of it may hinder counselors' proficient implementation of MI treatment strategies and the clients' motivational enhancement process. PMID:18835679

  17. The Superiority of Online Discussion: Faculty Perceptions

    ERIC Educational Resources Information Center

    Baglione, Stephen L.; Nastanski, Michael

    2007-01-01

    With online education continuing its meteoric rise, some educators continue to debate the efficacy of the medium--in particular, the ability to discuss complex subjects online. However, the online asynchronous discussion environment seems to offer some advantages over the traditional classroom including increased time for students to research and…

  18. Emergent Leadership in Children's Discussion Groups

    ERIC Educational Resources Information Center

    Li, Yuan; Anderson, Richard C.; Nguyen-Jahiel, Kim; Dong, Ting; Archodidou, Anthi; Kim, Il-Hee; Kuo, Li-Jen; Clark, Ann-Marie; Wu, Xiaoying; Jadallah, May; Miller, Brian

    2007-01-01

    Emergent leadership was examined in 12 discussion groups in 4 fourth-grade classrooms. Children's leadership moves were coded from transcripts of 10 free-flowing, open-format discussions of each of the 12 groups. The transcripts encompassed 26,000 turns for speaking, including 22,000 child turns of which 1,700 were judged to serve one of five…

  19. Involving Preservice Teachers in Discussions of Diversity.

    ERIC Educational Resources Information Center

    Daniel, Patricia L.; Benton, Janet E.

    Creating a safe, open environment for discussion is a critical first step in examining topics of diversity. Because public schools may be the only social arena in the United States where different social classes, ethnicities, and genders come together on a regular basis, it is important to involve preservice teachers in discussions involving…

  20. Clicking Our Way to Class Discussion

    ERIC Educational Resources Information Center

    Morse, Judith; Ruggieri, Margaret; Whelan-Berry, Karen

    2010-01-01

    The goal of this research project is to investigate whether the use of a personal response system ("clickers") in the classroom increases student participation and discussion and its impact on the quality of the discussion in undergraduate accounting courses. While many studies conducted regarding the use of clickers rely on student…

  1. Discussion-Based Instruction in Drug Metabolism.

    ERIC Educational Resources Information Center

    Ruenitz, Peter C.

    1995-01-01

    A flexible strategy for large-group pharmacy instruction in drug metabolism has students prepare and discuss answers to fact-oriented study questions, addressing fundamentals covered in a textbook, with regular evaluation of in-class student responses to higher-order review questions. This discussion-based approach has brought sustained…

  2. White Educators Facilitating Discussions about Racial Realities

    ERIC Educational Resources Information Center

    Quaye, Stephen John

    2012-01-01

    Facilitating democratic discussions about race among students in classroom environments continues to be a problem facing educators. When these discussions occur, they are facilitated mostly by faculty of color. However, given the underrepresentation of faculty of color within higher education institutions and that white students respond…

  3. Global Leadership Competencies: A Review and Discussion

    ERIC Educational Resources Information Center

    Jokinen, Tiina

    2005-01-01

    Purpose: From the competency point of view, this article aims to review and discuss existing global leadership and other related literature, and to combine findings and suggestions provided in previous literature in a more integrative framework of global leadership competencies. Design/methodology/approach: The paper reviews and discusses the…

  4. 33 CFR 240.5 - Discussion.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CREDIT FOR FLOOD CONTROL § 240.5 Discussion. Discussion of this legislation is contained in the... flood control works for projects under study. Both general provisions would enable local interests to... flood damages in the period preceding authorization of a Federal project with assurance that they...

  5. The Discussion Method in Classroom Teaching.

    ERIC Educational Resources Information Center

    Gall, Meredith Damien; Gillett, Maxwell

    1980-01-01

    Remarkably versatile and demonstrated as effective at all grade levels, the discussion method has great potential for classroom teaching. Teachers should use this method more often because it teaches students to speak freely, listen to others, analyze different points of view, and evaluate the effectiveness of a discussion. (CMJ)

  6. Threaded Discussion Instructional Strategies and Student Performance

    ERIC Educational Resources Information Center

    Krull, Rodger Pratt

    2013-01-01

    Educators need insight into what instructional strategies are effective in the online environment, but few researchers have contrasted threaded discussion strategies and measures of student performance using a quantitative approach. Also, the effectiveness of threaded discussion strategies across all student generation groups or between genders is…

  7. Managing the Paradoxes of Discussion Pedagogy

    ERIC Educational Resources Information Center

    Piro, Jody S.; Anderson, Gina

    2015-01-01

    Discussion pedagogy is part of a larger curricular goal that intersects the two aspirations of diversity of perspectives and democratic inquiry in that it challenges stereotypes and assumptions through student discourse. Yet, teaching with discussion is a complex and sometimes ambiguous endeavor that leaves instructors feeling pulled between…

  8. Building Knowledge and Community through Online Discussion

    ERIC Educational Resources Information Center

    Skinner, Elisabeth

    2007-01-01

    A web conference "adds value by generating discussion among a diverse student group" (Skinner, 2004a, p. 12). Or does it? A significant concern is the extent to which learners construct knowledge and develop a learning community through online discussion. Critics argue that genuine knowledge construction is difficult to achieve. This study…

  9. 33 CFR 214.6 - Discussion.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Discussion. 214.6 Section 214.6 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE EMERGENCY SUPPLIES OF DRINKING WATER § 214.6 Discussion. (a) The amendment provides for furnishing emergency supplies of drinking water. The method...

  10. 33 CFR 214.6 - Discussion.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Discussion. 214.6 Section 214.6 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE EMERGENCY SUPPLIES OF DRINKING WATER § 214.6 Discussion. (a) The amendment provides for furnishing emergency supplies of drinking water. The method...

  11. Asynchronous Discussions and Assessment in Online Learning

    ERIC Educational Resources Information Center

    Vonderwell, Selma; Liang, Xin; Alderman, Kay

    2007-01-01

    This case study explored asynchronous online discussions, assessment processes, and the meaning students derived from their experiences in five online graduate courses at the Colleges of Education of two Midwestern higher education institutions. The findings suggest that asynchronous online discussions facilitate a multidimensional process of…

  12. Discourse Patterns during Children's Collaborative Online Discussions

    ERIC Educational Resources Information Center

    Kim, Il-Hee; Anderson, Richard C.; Nguyen-Jahiel, Kim; Archodidou, Anthi

    2007-01-01

    This article examines the discourse of 10 groups of children during text-based online discussions. Analysis of the discourse in the discussions showed that 8 different rhetorical moves, or argument stratagems, were used by most groups of children, whereas 3 other stratagems were used by 1 group. The use of argument stratagems snowballed; that is,…

  13. Online Discussion, Student Engagement, and Critical Thinking

    ERIC Educational Resources Information Center

    Williams, Leonard; Lahman, Mary

    2011-01-01

    Recent research into the merits of online discussion (computer-mediated communication) has shown that it promotes active learning behaviors and enhances learner outcomes. Scholars have also shown that, when instructors employ effective questioning and moderating skills, students can show higher levels of critical thinking in online discussion. In…

  14. Discussion Starters. Technical Note No. 25.

    ERIC Educational Resources Information Center

    Yunus, Ibrahim; Dilts, Russ

    Discussion starters, the result of collaboration between the Indonesian Directorate General of Nonformal Education, Youth, and Sports, and World Education, Inc., are simple learning tools used to generate discussion among community groups involved in nonformal education. Appropriate in and adaptable to a variety of settings, content areas, and…

  15. Encouraging Critical Thinking in Online Threaded Discussions

    ERIC Educational Resources Information Center

    Arend, Bridget

    2009-01-01

    Critical thinking is a highly desirable goal of online higher education courses. This article presents qualitative data from a mixed-method study that explores how asynchronous discussions within online courses influence critical thinking among students. In this study, online discussions were related to higher levels of critical thinking, but…

  16. Integrating Online Discussion: Broadening the Conversation

    ERIC Educational Resources Information Center

    Li, Qing

    2006-01-01

    This article shares an approach to teaching mathematics teacher education courses incorporating asynchronous online discussions. Specifically, this research is guided by the following research questions: (a) How would online discussions contribute or hinder teachers' learning in mathematics methods courses? and (b) What pedagogical strategies need…

  17. The Adventure of the Discussion Board.

    ERIC Educational Resources Information Center

    Davis, Don

    This paper describes the frustration with the lack student involvement in classroom discussions regarding significant issues of the California State History Social Science Standards, specifically on politics and media. The initial use of a discussion board produced disappointing results. Very few students participated and their responses did not…

  18. Learning Reading Strategies with Online Discussion

    ERIC Educational Resources Information Center

    Liu, I-Fang; Ko, Hwa-Wei; Wu, Sheng-Yi

    2014-01-01

    Teachers experience difficulty demonstrating prediction strategies and leading discussions in traditional classrooms. It is also unclear whether online discussion can contribute to reading comprehension. The purpose of this study is to create an online reading system to investigate whether learners can acquire reading strategies and enhance their…

  19. What Is America? Discussions, Volume II.

    ERIC Educational Resources Information Center

    Roeder, Robert E., Ed.; And Others

    Volume II contains 20 discussion units for the final five months of the Calendar for the American Issues Forum Bicentennial program (see SO 008 613 for Vol. I). Discussion topics in this book include Working in America; the Business of America; America in the World; Growing up in America; and Life, Liberty, and the Pursuit of Happiness. Although a…

  20. Preparing Teachers to Lead Mathematics Discussions

    ERIC Educational Resources Information Center

    Boerst, Timothy A.; Sleep, Laurie; Ball, Deborah Loewenberg; Bass, Hyman

    2011-01-01

    Background/Context: Discussion is central to mathematics teaching and learning, as well as to mathematics as an academic discipline. Studies have shown that facilitating discussions is complex work that is not easily done or learned. To make such complex aspects of the work of teaching learnable by beginners, recent research has focused on…

  1. Affordances and Constraints of Electronic Discussions.

    ERIC Educational Resources Information Center

    Hunt, Russell A.

    The most common consequence of setting up an "electronic discussion group" for a university class or a group of faculty is a flurry of initial greetings followed by an enduring silence. Only a small proportion of computer users are active and sophisticated enough to read regularly and feel disposed to participate actively. Written discussion may…

  2. Discussion Forum for Technical Codes Users

    SciTech Connect

    Kaspar, Bryce P.; Dillon, Heather E.

    2006-03-30

    One goal of the Building Energy Codes Program (BECP) is to provide useful, easy to understand information about the national energy codes. A forum where users could ask for, and receive clarification on these codes and software from other users would allow the Energy codes project to reach and instruct a broader audience for a modest resource cost. The forum proposed would be a staff moderated discussion board where staff would post topics, and users would post discussion of those topics, with staff joining in to the discussions. The forum would be moderated by staff members, to remove objectionable and irrelevant postings, and to answer any technical questions that arise. The topics and discussions would be archived and searchable to allow users to answer their own questions, if they pertain to a previously discussed topic.

  3. National GAP Conference 2007-Discussion Groups Report

    USGS Publications Warehouse

    Ratz, Joan M.; Lamb, Berton Lee

    2010-01-01

    We led two discussion groups during the 2007 National GAP Conference. These discussion groups provided information to help develop a survey of National Gap Analysis Program (GAP) data users. One group discussed technical issues, and the second group discussed the use of GAP data for decisionmaking. Themes emerging from the technical issues group included concerns about data quality, need for information on how to use data, and passive data distribution. The decisionmaking discussion included a wide range of topics including the need to understand presentation of information, the need to connect with and understand users of data, the revision of GAP's mission, and the adaptability of products and data. The decisionmaking group also raised concerns regarding technical issues. One conclusion is that a deep commitment to ongoing information transfer and support is a key component of success for the GAP program.

  4. Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans

    PubMed Central

    Wang, Hong X.; Douglas, Lois M.; Veselá, Petra; Rachel, Reinhard; Malinsky, Jan; Konopka, James B.

    2016-01-01

    The plasma membrane of the fungal pathogen Candida albicans forms a protective barrier that also mediates many processes needed for virulence, including cell wall synthesis, invasive hyphal morphogenesis, and nutrient uptake. Because compartmentalization of the plasma membrane is believed to coordinate these diverse activities, we examined plasma membrane microdomains termed eisosomes or membrane compartment of Can1 (MCC), which correspond to ∼200-nm-long furrows in the plasma membrane. A pil1∆ lsp1∆ mutant failed to form eisosomes and displayed strong defects in plasma membrane organization and morphogenesis, including extensive cell wall invaginations. Mutation of eisosome proteins Slm2, Pkh2, and Pkh3 did not cause similar cell wall defects, although pkh2∆ cells formed chains of furrows and pkh3∆ cells formed wider furrows, identifying novel roles for the Pkh protein kinases in regulating furrows. In contrast, the sur7∆ mutant formed cell wall invaginations similar to those for the pil1∆ lsp1∆ mutant even though it could form eisosomes and furrows. A PH-domain probe revealed that the regulatory lipid phosphatidylinositol 4,5-bisphosphate was enriched at sites of cell wall invaginations in both the sur7∆ and pil1∆ lsp1∆ cells, indicating that this contributes to the defects. The sur7∆ and pil1∆ lsp1∆ mutants displayed differential susceptibility to various types of stress, indicating that they affect overlapping but distinct functions. In support of this, many mutant phenotypes of the pil1∆ lsp1∆ cells were rescued by overexpressing SUR7. These results demonstrate that C. albicans eisosomes promote the ability of Sur7 to regulate plasma membrane organization. PMID:27009204

  5. The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman

    PubMed Central

    Akasaka, Takeshi; Klinedinst, Susan; Ocorr, Karen; Bustamante, Erika L.; Kim, Seung K.; Bodmer, Rolf

    2006-01-01

    The homeobox transcription factor Tinman plays an important role in the initiation of heart development. Later functions of Tinman, including the target genes involved in cardiac physiology, are less well studied. We focused on the dSUR gene, which encodes an ATP-binding cassette transmembrane protein that is expressed in the heart. Mammalian SUR genes are associated with KATP (ATP-sensitive potassium) channels, which are involved in metabolic homeostasis. We provide experimental evidence that Tinman directly regulates dSUR expression in the developing heart. We identified a cis-regulatory element in the first intron of dSUR, which contains Tinman consensus binding sites and is sufficient for faithful dSUR expression in the fly’s myocardium. Site-directed mutagenesis of this element shows that these Tinman sites are critical to dSUR expression, and further genetic manipulations suggest that the GATA transcription factor Pannier is synergistically involved in cardiac-restricted dSUR expression in vivo. Physiological analysis of dSUR knock-down flies supports the idea that dSUR plays a protective role against hypoxic stress and pacing-induced heart failure. Because dSUR expression dramatically decreases with age, it is likely to be a factor involved in the cardiac aging phenotype of Drosophila. dSUR provides a model for addressing how embryonic regulators of myocardial cell commitment can contribute to the establishment and maintenance of cardiac performance. PMID:16882722

  6. Chinese women's participation in fertility discussions.

    PubMed

    Li, L

    1993-01-01

    In an attempt to better understand the process through which the family planning (FP) programs and socioeconomic developments in China affect fertility, women's participation in fertility discussions with their husbands are examined as an intermediate factor in a study based on results of a random survey of 6654 ever-married women of reproductive age from 7 cities and 30 counties of Guangdong. First, it must be noted that Chinese couples do have individual choices (albeit quite limited ones) about their fertility; they can choose to follow or ignore government policy or they can choose to remain childless. The present study has 3 major hypotheses: 1) the more a woman is involved in fertility discussions with her husband, the fewer children she will have; 2) urban women with a higher educational status will be more likely to have such discussions; and 3) women who are contacted individually by FP personnel are more likely to be involved in fertility discussions. After a discussion of data collection and variables (number of living children, education of wife and husband, age at marriage, residence, living with parents, contacted by FP personnel, and discussion with husband), the results are presented in terms of zero-order correlation coefficients indicating their relationships. The bivariate analysis supported the hypotheses. Multiple regression analysis showed that age at marriage, education of wives and husbands, FP contacts, and participation in discussions remain significant fertility determinants (but the correlation between fertility and residence becomes trivial). A further regression model indicated that a woman's educational attainment is the most significant positive indication of their participation in fertility discussions. These results imply that as women's status continues to improve in China and the deeply-rooted patriarchal tradition loses hold, increased gender equity and education will influence a fertility decline. FP personnel could also

  7. An Elementary Discussion of Chemical Equilibrium.

    ERIC Educational Resources Information Center

    David, Carl W.

    1988-01-01

    This discussion uses a more difficult reaction as the prototype to derive the standard equation for chemical equilibrium. It can be used by students who can understand and use partial derivatives. (CW)

  8. Exploring the Use of Discussion Strategies and Labels in Asynchronous Online Discussion

    ERIC Educational Resources Information Center

    Gao, Fei

    2014-01-01

    Drawing on research in constrained online discussion environments and strategy instruction, this approach combines explicit instruction on discussion strategies with the use of post type labels. In a trial of this approach in an online course, students actively used the discussion strategies and post type labels in their discussions. Analysis of…

  9. Online Discussions: A Survey of Advantages and Disadvantages Compared to Face-to-Face Discussions.

    ERIC Educational Resources Information Center

    Tiene, Drew

    2000-01-01

    Reports results of surveys of graduate students involved in online class discussions that show a preference for face-to-face experiences in spite of positive reactions to online discussions. Online discussions were perceived as valuable additions to in-class discussions, rather than as an acceptable substitution for them. (Author/LRW)

  10. A Qualitative Case Study Illustrating the Benefits of Discussion Roles in Online Asynchronous Discussion

    ERIC Educational Resources Information Center

    Hancock, Cheryl J.

    2012-01-01

    This research describes a qualitative, naturalistic case study of a situation-specific, in-depth exploration of the use of ten student discussion roles in and adult education, online asynchronous discussions. Discussion roles were designed in order to enable students to respond better and create deeper and more meaning-filled threaded discussions,…

  11. Parier sur le francais fonctionnel (Betting on Functional French).

    ERIC Educational Resources Information Center

    Larramendy, Jean-Louis

    1990-01-01

    A discussion of second-language learning looks at the role of functional French in the acquisition of French as a second or foreign language. The choice and implementation of a Vygotskian approach using the study of electricity is described. (MSE)

  12. The Palaeodiet of the Pericue Indians of the Cape Region of Baja California Sur, Mexico.

    NASA Astrophysics Data System (ADS)

    Beer, N.; Gonzalez, S.; Huddart, D.; Rosales-Lopez, A.; Lamb, A.

    2008-05-01

    The archaeology of the Pericue Indians inhabiting the Cape region of Baja California has long been an area of interest. The dolichocranic traits exhibited by this population have lead to suggestions that these people were a relic population of an early coastal migration into North America. The antiquity of directly dated Pericue human remains only reaches 3,000 B.P. with occupation sites dating back to 9,000 B.P. The site of Babisuri cave in Isla Espiritu Santo may demonstrate a very early human presence in Baja California Sur between 36,000 to 45,000 B.P. although the exact nature of this evidence is unclear. Increasing tourist development within this region threatens many archaeological sites particularly coastal shell middens and rock shelters. Current rescue excavations are yielding important information regarding many aspects of the culture of the Pericue Indians. Geochemical evidence of diet {d13C and d15N} taken from Pericue bone samples, modern and archaeological animals and modern plants is helping us to understand the complicated subsistence strategies of this group. Initial results highlight a complicated and diverse diet including marine and terrestrial resources, most likely exploited seasonally. Similarities between the diet of the Pericue and other nearby coastal Indian groups are clear and will be discussed. Pericue Indian material culture, combined with the exploitation of marine mammals and the construction of enormous shell mounds display parallels with other central and North American groups. The exploitation of marine mammals and the associated stone tools display striking similarities to the Chumash people of the Channel Islands of Coastal Southern California. Some of these cultural similarities will be highlighted in this presentation. Current genetic work is attempting to discover the nature of the similarities between the Chumash and Pericue groups as some cultural elements of each group have parallels with the other. Initial genetic

  13. Évolution des lignes directrices sur le traitement de la dyslipidémie

    PubMed Central

    John Bosomworth, N.

    2014-01-01

    Résumé Objectif Comprendre comment les nouvelles lignes directrices sur la prise en charge du risque cardiovasculaire publiées par l’American Heart Association et l’American College of Cardiology (AHA-ACC) peuvent être interprétées et utilisées dans le contexte canadien. Sources des données Les lignes directrices de l’AHA-ACC ont été examinées, de même que toutes les références. Des recherches indépendantes dans PubMed ont été effectuées pour inclure l’ajout aux statines d’autres antihyperlipidémiants et l’emploi de calculatrices médicales visant à aider le patient à comprendre. Message principal Les nouvelles lignes directrices de l’AHA-ACC s’appuient sur les meilleures données probantes disponibles actuellement en matière de traitement de la dyslipidémie. Cela inclut le risque cardiovasculaire (CV) sur 10 ans comme seuil thérapeutique au lieu du taux de cholestérol des lipoprotéines de faible densité, de même que l’abandon des cibles thérapeutiques de lipoprotéines de faible densité. On met de plus en plus l’accent sur les interventions alimentaires et l’exercice, avec l’amorce d’un effort pour quantifier l’effet de ces interventions. Les statines constituent la principale intervention pharmacologique, et l’ajout d’autres médicaments pour accentuer la baisse lipidique n’est plus recommandé. En ce qui concerne l’application au Canada, les tables de risque de Framingham sont plus appropriées pour évaluer le risque que les équations de cohortes regroupées utilisées aux États-Unis. Les calculatrices du risque de maladie cardiovasculaire (MCV) devraient contenir de l’information sur l’âge cardiovasculaire et devraient pouvoir illustrer le risque et les interventions de rechange afin d’aider le patient à comprendre et de favoriser la prise de décision éclairée. Conclusion L’attention sur les meilleures données probantes concernant le risque CV peut simplifier le traitement de la

  14. [A glossary for discussion about abortion].

    PubMed

    Astete A, Carmen; Beca I, Juan Pablo; Lecaros U, Alberto

    2014-11-01

    Abortion and its diverse possible legal regulations is one of the major and toughest social controversies. This debate is even more problematic due to biases, prejudgments, different ideologies, beliefs, religious doctrines and political pressures. Chile has recently begun a new national discussion with an evident confusion, both in juridical and clinical terminology, which makes very difficult to achieve the necessary plural debate for a social and political consensus. The authors structured an academic collaborative project to create a glossary as a contribution for a discussion based on clearly defined notions about the different terms used in the abortion debate. Twenty-two concepts were selected and their definitions were reviewed and discussed by more than 50 different specialists. The final version of this glossary in Spanish language is presented. PMID:25694291

  15. A Discussion of Knowledge Based Design

    NASA Technical Reports Server (NTRS)

    Wood, Richard M.; Bauer, Steven X. S.

    1999-01-01

    A discussion of knowledge and Knowledge- Based design as related to the design of aircraft is presented. The paper discusses the perceived problem with existing design studies and introduces the concepts of design and knowledge for a Knowledge- Based design system. A review of several Knowledge-Based design activities is provided. A Virtual Reality, Knowledge-Based system is proposed and reviewed. The feasibility of Virtual Reality to improve the efficiency and effectiveness of aerodynamic and multidisciplinary design, evaluation, and analysis of aircraft through the coupling of virtual reality technology and a Knowledge-Based design system is also reviewed. The final section of the paper discusses future directions for design and the role of Knowledge-Based design.

  16. Discussion of difficult assessment cases: psychodynamic perspectives.

    PubMed

    Yalof, Jed

    2015-01-01

    I discuss the papers of Kleiger (this issue), Husain (this issue), and Bram (this issue), each of whom described their personality assessment of a very challenging case. Each case illustrates the way in which experienced personality assessors integrate psychoanalytic theory with clinical reasoning, multi-method assessment, and an understanding of the patient-examiner relationship when evaluating patients with serious psychiatric needs. The discussion elaborates particular aspects of each case and integrates the different estuaries through which personality assessors use psychoanalytic theory to develop diagnostic and treatment inferences. PMID:25746100

  17. Informal Learning of Young Children: Discussion.

    ERIC Educational Resources Information Center

    Sutton-Smith, Brian

    This paper, a discussion of papers by Robert S. Randall, Greta Fein, Richard Bauman and Murray Newman, looks at informal learning from an anthropological viewpoint with an emphasis on inversive theory. It is suggested that the irrational elements of informal learning, the combinations of order and disorder, allow children to relate to reality by…

  18. Theses "Discussion" Sections: A Structural Move Analysis

    ERIC Educational Resources Information Center

    Nodoushan, Mohammad Ali Salmani; Khakbaz, Nafiseh

    2011-01-01

    The current study aimed at finding the probable differences between the move structure of Iranian MA graduates' thesis discussion subgenres and those of their non-Iranian counterparts, on the one hand, and those of journal paper authors, on the other. It also aimed at identifying the moves that are considered obligatory, conventional, or optional…

  19. Measuring Faculty Participation in Asynchronous Discussion Forums.

    ERIC Educational Resources Information Center

    Blignaut, A. Signet; Trollip, Stanley R.

    2003-01-01

    A taxonomy of types of faculty participation in online course discussions was developed and a survey of 18 online business instructors and administrators was used to develop expectations for type and number of feedback messages. Results were used to analyze business courses and develop guidelines for teachers' role. (Contains 13 references.) (SK)

  20. Studying School Leadership Practice: A Methodological Discussion

    ERIC Educational Resources Information Center

    Eacott, Scott

    2010-01-01

    This paper seeks to engage the field of educational leadership in a methodological conversation. It outlines a methodological position taken by the author (a focus on leadership practice using Bourdieu) in a currently funded project and seeks discussion with the wider field. The paper is structured to provide the reader with background to the…

  1. Alice, Greenfoot, and Scratch--A Discussion

    ERIC Educational Resources Information Center

    Utting, Ian; Cooper, Stephen; Kolling, Michael; Maloney, John; Resnick, Mitchel

    2010-01-01

    This article distills a discussion about the goals, mechanisms, and effects of three environments which aim to support the acquisition and development of computing concepts (problem solving and programming) in pre-University and non-technical students: Alice, Greenfoot, and Scratch. The conversation started in a special session on the topic at the…

  2. What Is Formation? A Conceptual Discussion

    ERIC Educational Resources Information Center

    Sutphen, Molly; de Lange, Thomas

    2015-01-01

    This paper addresses the principles and connotations of the term "formation." In our discussion of formation, we draw on different disciplines in order to widen and deepen our understanding of the concept of formation. We also mirror the formation concept against comparable terms and draw on studies in which it has been applied in…

  3. Indians and the Media: A Panel Discussion

    ERIC Educational Resources Information Center

    Civil Rights Digest, 1973

    1973-01-01

    An exploration of communications and the approximately one million Indian people who live in the U.S., by people in film, television, radio, and print news; condensed from the transcript of a panel discussion held July 6, 1973 in conjunction with the Smithsonian Institution's Folklife Festival in Washington, D.C. (Author/JM)

  4. Theory and Distance Education: A New Discussion.

    ERIC Educational Resources Information Center

    Simonson, Michael; Schlosser, Charles; Hanson, Dan

    1999-01-01

    Discusses the need for theory in the field of distance education, reviews several traditional theoretical approaches, and describes a new theory called Equivalency Theory that incorporates telecommunications. Compares theories of independence and autonomy, industrialization of teaching, and interaction and communication. (LRW)

  5. Janet Saltzman Chafetz Plenary: Discussant Comments

    ERIC Educational Resources Information Center

    Allen, Katherine R.

    2004-01-01

    Feminist ideas and practices permeate the consciousness, relationships, and politics of women and men across continents. Certainly, they are central to work in the scientific study of family structures and processes. It is exciting to engage in discussion and debate with other feminist scholars about the relative contributions of feminist theories…

  6. Popular Magazines Discuss Online Information Retrieval.

    ERIC Educational Resources Information Center

    Diodato, Virgil

    1984-01-01

    Examines 55 articles from 25 popular magazines such as "Better Homes and Gardens,""Business Week,""Popular Mechanics," and "Working Woman" and discusses purpose of the articles, consumer oriented online services, libraries and information centers, databases, and publishers and intermediaries. A list of the articles is appended. (EJS)

  7. NEUROTOXICITY OF TETRACHLOROETHYLENE (PERCHLOROETHYLENE): DISCUSSION PAPER

    EPA Science Inventory

    This paper is a background document for a meeting of neurotoxicity experts to discuss the central nervous system effects of exposure to perchloroethylene (perc). The document reviews the literature on neurological testing of people exposed to perc occupationally in dry cleanin...

  8. On psychotherapist-patient sex: discussion paper.

    PubMed Central

    Palermo, G B

    1990-01-01

    The transference phenomenon as central to the problem of sex between psychotherapist and patient is discussed. Socio-semantic factors related to the evolution of psychotherapy from Freud to the present are presented. Contemporary pertinent studies are reported. Societal and legal attitudes towards offending therapists are briefly touched upon. Reflections are made and suggestions are offered for dealing with this serious issue. PMID:2250271

  9. Corruptness in Education: A Tentative Discussion

    ERIC Educational Resources Information Center

    Dongping, Yang

    2004-01-01

    With more and more instances of corruptness coming to light in the field of education, corruptness in education has become an intense "hot point" of concern in society. This article is a tentative exploration into this matter. In this article, the author discusses the categories of the corruptness in education that has found widespread publicity…

  10. Unseen Discussions: Artist@Hotmail.Com.

    ERIC Educational Resources Information Center

    Huberman, Anthony

    For the recent exhibition "Greater New York: New Art in New York Now," the Education Department at P.S.1 Contemporary Art Center, a large museum located in the Long Island City section of Queens, New York, organized a unique email-based discussion. The museum set up an e-mail address for most participating artists using the free Hotmail.com…

  11. Discussion Paper on Digital Copyright Issues.

    ERIC Educational Resources Information Center

    2001

    The Copyright Forum serves as a venue for the discussion of digital copyright issues of interest to Canadian educational institutions, libraries, archives, and museums. The Forum currently comprises 13 national associations. The members of the participating associations are both creators and users of digital intellectual content, and a number of…

  12. 33 CFR 214.6 - Discussion.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... providing emergency supplies of clean drinking water. Sewage treatment and disposal, and other sanitary... SUPPLIES OF DRINKING WATER § 214.6 Discussion. (a) The amendment provides for furnishing emergency supplies of drinking water. The method of furnishing those supplies is not provided for in the amendment,...

  13. 33 CFR 214.6 - Discussion.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... providing emergency supplies of clean drinking water. Sewage treatment and disposal, and other sanitary... SUPPLIES OF DRINKING WATER § 214.6 Discussion. (a) The amendment provides for furnishing emergency supplies of drinking water. The method of furnishing those supplies is not provided for in the amendment,...

  14. 33 CFR 214.6 - Discussion.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... providing emergency supplies of clean drinking water. Sewage treatment and disposal, and other sanitary... SUPPLIES OF DRINKING WATER § 214.6 Discussion. (a) The amendment provides for furnishing emergency supplies of drinking water. The method of furnishing those supplies is not provided for in the amendment,...

  15. Online Discussion about Sexuality Education in Schools

    ERIC Educational Resources Information Center

    Broadbear, James T.; Broadbear, Barbara C.

    2012-01-01

    Sexuality education in schools continues to be a controversial issue although public debate has seemingly calmed in recent years. Dialogue about the value and purpose of sexuality education for adolescents can provide health education specialists a better understanding of public opinion and online discussion may be a potentially ideal way to…

  16. A Discussion Strategy for an Online Class

    ERIC Educational Resources Information Center

    Reese-Durham, Nancy Faith

    2014-01-01

    As a former teacher of face-to-face classes now assigned to teach only online classes, Nancy Reese Durham found herself challenged to change to accommodate online learners. She was determined to provide an environment in the online class where the high level of discussion she had provided in face-to-face classes could flourish as well. Here she…

  17. Workplace Mobbing: A Discussion for Librarians

    ERIC Educational Resources Information Center

    Hecker, Thomas E.

    2007-01-01

    Workplace mobbing occurs in libraries but is usually unrecognized and unchecked because the phenomenon has not been described and given a name. This discussion provides the library profession with an overview but also with specific background details to assist with recognizing mobbing and preventing severe harm to employees and organizations.

  18. Young Scientists Discuss Recent Advances, Future Challenges.

    ERIC Educational Resources Information Center

    Baum, Rudy M.

    1989-01-01

    Discusses a National Academy of Science forum at which a group of outstanding young researchers in astronomy, molecular and developmental biology, physics, chemistry, mathematics, atmospheric science, and materials science met for three days of formal presentations and informal conversations. Provides a short synopsis of major speakers. (MVL)

  19. Functions of Symbolizing Activity: A Discussion

    ERIC Educational Resources Information Center

    Tillema, Erik

    2010-01-01

    I propose that attending how symbolizing activity functions for teachers and students helps to characterize student-teacher communication, and allows for an investigation of how symbolizing activity contributes to learning. I begin this discussion by articulating four ideas-schemes, symbolizing activity, communication, and learning. Then I propose…

  20. Discover Presidential Log Cabins. Teacher's Discussion Guide.

    ERIC Educational Resources Information Center

    National Park Service (Dept. of Interior), Washington, DC.

    Discover Presidential Log Cabins is a set of materials designed to help educate 6-8 grade students about the significance of three log cabin sites occupied by George Washington, Ulysses Grant, Abraham Lincoln, and Theodore Roosevelt. This teacher's discussion guide is intended for use as part of a larger, comprehensive social studies program, and…

  1. Online Discussion Assignments Improve Students' Class Preparation

    ERIC Educational Resources Information Center

    Lineweaver, Tara T.

    2010-01-01

    To increase the number of students who read the text before class and to promote student interaction centering on text material, I developed an online discussion assignment as a required component of a cognitive psychology course. Across 2 studies, this assignment had a limited effect on examination performance, but students completing online…

  2. Discussion: the radiobiological bases of TBI

    SciTech Connect

    Peters, L.

    1980-06-01

    With the use of TBI, dose limiting normal tissues must be considered in treatment planning. The sensitivity of the lungs, gastrointestinal tract, and heart are discussed in view of cell survival curves of proposed target cells with emphasis upon radiation fractionation as a dose-limiting factor. (DLS)

  3. Teaching medical humanities through film discussions.

    PubMed

    Self, Donnie J; Baldwin, DeWitt C

    1990-01-01

    Following a brief consideration of two contrasting purposes for teaching the medical humanities, a description is given of a film discussion elective course. In contrast to the usual teaching of medical ethics which is primarily a cognitive activity emphasizing the development of a code of principles such as justice, autonomy, and beneficence, the film discussion elective was primarily an affective activity emphasizing the development of an ethical ideal of caring, relatedness, and sensitivity to others. The pass/fail elective, offered for one credit each quarter for two quarters, met once a week for one hour for twenty-four weeks. Each week a film was shown followed by a group discussion. A wide variety of social issues were covered. The objective of the course was to increase the ethical sensitivity of the medical students through promotion of introspection and reflection on social issues. A brief discussion is given of the importance and appropriateness of using film to promote the affective focus of medicine on the relief of the suffering. Examples are given of how the course achieved its objective. A detailed description of the resource materials is provided. PMID:11645721

  4. 48 CFR 1.102-1 - Discussion.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... procedures in the FAR. (b) Vision. All participants in the System are responsible for making acquisition... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Discussion. 1.102-1 Section 1.102-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL...

  5. School PE through Internet Discussion Forums

    ERIC Educational Resources Information Center

    Lauritsalo, Kirsti; Sääkslahti, Arja; Rasku-Puttonen, Helena

    2015-01-01

    Background: Physical education is a subject that generates strong feelings and emotions, as can be seen in written accounts of PE experiences. It is also important to listen to students' voices in the research context. Nowadays, students can be listened to in a new way--through the Internet. Various discussion forums on the Internet make it…

  6. Discussing Diabetes with Your Healthcare Provider

    MedlinePlus

    ... Provider Past Issues / Fall 2009 Table of Contents Diabetes Medicines—Always Discuss Them with Your Healthcare Provider If ... NIHSeniorHealth: Diabetes http://nihseniorhealth.gov/diabetes/toc.html Weekly email updates: MEDLINEPLUS-DIABETES: Subscribe from https://list. ...

  7. Principals Discuss Their Roles: An Observational Study.

    ERIC Educational Resources Information Center

    Rogers, Kathryn S.

    What principals are taught about their roles differs markedly from how they actually perceive and experience their roles. To discover the principals' views, comments made in discussion groups by 44 principals in a large urban Midwest school system over a four-month period were analyzed. Their descriptions of their roles and desired role changes…

  8. 5 Practices for Orchestrating Productive Mathematics Discussions

    ERIC Educational Resources Information Center

    Stein, Mary Kay; Smith, Margaret

    2011-01-01

    Learn the 5 practices for facilitating effective inquiry-oriented classrooms: (1) Anticipating what students will do--what strategies they will use--in solving a problem; (2) Monitoring their work as they approach the problem in class; (3) Selecting students whose strategies are worth discussing in class; (4) Sequencing those students'…

  9. Language and Music as Communication: A Discussion.

    ERIC Educational Resources Information Center

    Brown, Roger; And Others

    1979-01-01

    Roger Brown, Diana Deutsch, Warren Benson, and Ruth Day comment on the similarities and differences between verbal language and music as forms of communication. This discussion occurred at the first session of the National Symposium on the Applications of Psychology to the Teaching and Learning of Music, Ann Arbor. (SJL)

  10. Discussed Issues in Preventive Intervention Programs

    ERIC Educational Resources Information Center

    Ocak, Sakire

    2011-01-01

    The growing number of studies in the field of prevention science and related advancements in evidence based programs leads to some discussions about the fundamental issues such as efficacy, effectiveness, dissemination, adaptation, fidelity and continuity in recent years. In this article it is intended to report the common views of early childhood…

  11. Examining the Doctoral Thesis: A Discussion

    ERIC Educational Resources Information Center

    Carter, Susan

    2008-01-01

    The examination of doctoral theses controls an important academic threshold, yet practices are often private, codes non-specific, and individuals isolated. This article adds to recent investigation of the examination culture by reporting informal panel discussion amongst a total of 23 University of Auckland (New Zealand) faculty members as to…

  12. A Discussion of Future Time Perspective

    ERIC Educational Resources Information Center

    McInerney, Dennis M.

    2004-01-01

    A growing area of research in educational psychology is future time perspective and its relationship to desired educational outcomes. This article discusses and critiques five reviews of current research on future time perspective. Key questions addressed are when do individuals begin to articulate a future, how far into the future does this…

  13. Lander Propulsion Overview and Technology Requirements Discussion

    NASA Technical Reports Server (NTRS)

    Brown, Thomas M.

    2007-01-01

    This viewgraph presentation reviews the lunar lander propulsion requirements. It includes discussion on: Lander Project Overview, Project Evolution/Design Cycles, Lunar Architecture & Lander Reference Missions, Lander Concept Configurations, Descent and Ascent propulsion reviews, and a review of the technology requirements.

  14. Promoting Discussion in Peer Instruction: Discussion Partner Assignment and Accountability Scoring Mechanisms

    ERIC Educational Resources Information Center

    Chou, Chih-Yueh; Lin, Pin-Hsun

    2015-01-01

    Peer instruction (PI) involves students answering questions and peer discussion learning activities. PI can enhance student performance and engagement in classroom instruction. However, some students do not engage in the discussions. This study proposes two mechanisms, discussion partner assignment and accountability scoring mechanisms, to form…

  15. Literature Discussion as Positioning: Examining Positions in Dialogic Discussions in a Third-Grade Classroom

    ERIC Educational Resources Information Center

    Wee, Jongsun

    2010-01-01

    The purpose of the study is to examine positions of students and a teacher in dialogic discussion. In this study, dialogic discussion was defined with Bakhtin's (1981) dialogism, Nystrand's (1997) explanation of dialogically organized instruction, and Mercer's (1995) explanation of Exploratory Talk. Studies about literature discussion in…

  16. Dual response of the KATP channels to staurosporine: a novel role of SUR2B, SUR1 and Kir6.2 subunits in the regulation of the atrophy in different skeletal muscle phenotypes.

    PubMed

    Mele, Antonietta; Camerino, Giulia M; Calzolaro, Sara; Cannone, Maria; Conte, Diana; Tricarico, Domenico

    2014-09-15

    We investigated on the role of the genes encoding for the ATP-sensitive K(+)-channel (KATP) subunits (SUR1-2A/B, Kir6.2) in the atrophy induced "in vitro" by staurosporine (STS) in different skeletal muscle phenotypes of mouse. Patch-clamp and gene expression experiments showed that the expression/activity of the sarcolemma KATP channel subunits was higher in the fast-twitch than in the slow-twitch fibers. After 1 to 3h of incubation time, the STS (2.14×10(-6)M) treatment enhanced the expression/activity of the SUR2B, SUR1 and Kir6.2 subunit genes, but not SUR2A, in the slow-twitch muscle fibers, induced the caspase-3-9, Atrogin-1 and Murf-1 gene expression without affecting protein content. After 3 to 6h, the STS-related atrophy markedly down-regulated the SUR2B, SUR1 and Kir6.2 genes reducing the KATP currents and reduced the protein content/muscle weight ratio of the slow-twitch muscle by -36.4±6% (p<0.05). After 6 to 24h, no additional changes of the SUR1-2B and Kir6.2 gene expression and muscle protein were observed. In the fast-twitch muscles, STS mildly affected the atrophic genes and protein content, but potentiated the KATP currents down-regulating the Bnip-3 gene. Diazoxide (250-500×10(-6)M), a SUR1-2B/Kir6.2 channel opener, prevented the protein loss induced by STS in the slow-twitch muscle after 6h showing an EC50 of 1.35×10(-7)M and Emax of 75%, down-regulated the caspase-9 gene and enhanced the KATP currents. The enhanced expression/activity of the SUR2B, SUR1 and Kir6.2 genes are cytoprotective against STS-induced atrophy in the slow-twitch muscle; their reduced expression/activity is associated with proteolysis and atrophy in skeletal muscle. PMID:24998494

  17. Open problems in color constancy: discussion.

    PubMed

    van Trigt, C

    2014-02-01

    This paper discusses a number of open problems in color constancy theory whose correct solution is a prerequisite for the theory of the phenomenon. Solutions employing suitable visually meaningful versus physically meaningful basis functions (principal components) are examined. In the former case the starting point is an estimate of the first derivative of the reflectance (illuminant), essential for defining color, instead of an estimate of the reflectance (illuminant), as in the latter. Conceptual consequences are discussed. Mathematical and physical constraints are identified. We compare the results of theories that do or do not ignore them. The following questions are considered. (1) Do unique solutions of the estimation problem exist everywhere in the object-color solid belonging to the illuminant? (2) Are they physically meaningful, i.e., at least nonnegative? (3) Are they representative for reflectance and spectral distribution functions? (4) What role plays metamerism? PMID:24562033

  18. Quantum clock: A critical discussion on spacetime

    NASA Astrophysics Data System (ADS)

    Burderi, Luciano; Di Salvo, Tiziana; Iaria, Rosario

    2016-03-01

    We critically discuss the measure of very short time intervals. By means of a Gedankenexperiment, we describe an ideal clock based on the occurrence of completely random events. Many previous thought experiments have suggested fundamental Planck-scale limits on measurements of distance and time. Here we present a new type of thought experiment, based on a different type of clock, that provide further support for the existence of such limits. We show that the minimum time interval Δ t that this clock can measure scales as the inverse of its size Δ r . This implies an uncertainty relation between space and time: Δ r Δ t >G ℏ/c4, where G , ℏ, and c are the gravitational constant, the reduced Planck constant, and the speed of light, respectively. We outline and briefly discuss the implications of this uncertainty conjecture.

  19. How to write a discussion section?

    PubMed

    Şanlı, Öner; Erdem, Selçuk; Tefik, Tzevat

    2013-09-01

    Writing manuscripts to describe study outcomes, although not easy, is the main task of an academician. The aim of the present review is to outline the main aspects of writing the discussion section of a manuscript. Additionally, we address various issues regarding manuscripts in general. It is advisable to work on a manuscript regularly to avoid losing familiarity with the article. On principle, simple, clear and effective language should be used throughout the text. In addition, a pre-peer review process is recommended to obtain feedback on the manuscript. The discussion section can be written in 3 parts: an introductory paragraph, intermediate paragraphs and a conclusion paragraph. For intermediate paragraphs, a "divide and conquer" approach, meaning a full paragraph describing each of the study endpoints, can be used. In conclusion, academic writing is similar to other skills, and practice makes perfect. PMID:26328131

  20. Career Opportunities for Physicists: Panel Discussion

    NASA Astrophysics Data System (ADS)

    2016-03-01

    We live in a world full of opportunity for physics graduates. Join us for a unique opportunity to learn about some of these opportunities from our diverse panel of working physicists from industrial, national lab, and academic sectors. Topics of discussion will include panelists' daily experiences, how physics serves them in their career, and advice to students interested in following a similar path. Light refreshments will be served.

  1. Attorney for Cruzans discusses legal 'odyssey'.

    PubMed

    1991-06-01

    On December 11, 1983, 25-year-old Missourian Nancy Cruzan was in a serious car accident, pronounced dead at the scene by police then resuscitated by paramedics. On December 14, 1990, the gastrostomy tube which had kept Nancy alive since the accident was removed and she died 11 days later. The heartbreak, legal maneuvering and impassioned discussions of the 8 years between these events captured the attention of the nation. PMID:1906440

  2. Complications of Poly Implant Prothèse breast implants: the current discussion.

    PubMed

    Kolios, Leila; Hirche, Christoph; Spiethoff, Alexander; Daigeler, Adrien; Lehnhardt, Marcus

    2013-03-01

    Against the background of the current discussion about Poly Implant Prothèse (PIP, Seyne-sur-mer, France) breast implants, we want to present a case demonstrating the complications such as implant rupture, silicone dissemination and level III silicone lymphadenopathy. A 29-year-old woman with cosmetic breast augmentation with PIP implants 5 years previously showed a sensitive swelling in her right axilla and neck region. All tests to detect an infectious or lymphomatous lymphadenopathy were negative. After ultrasound and MRI, rupture of the right implant was assumed and multiple pathologically enlarged lymph nodes up to supraclavicular region were shown. An excision biopsy of one axillary lymph node was performed; the histological examination detected a strong silicone lymphadenopathy. Surgical removal of both implants as well as capsulectomy was performed and 14 axillary lymph nodes up to level II were resected. Histologic evaluation confirmed the previous results. Our case underlines the actual discussion concerning increased rupture rate and massive silicone lymphadenopathy by PIP implants. The Agence Francaise de Sécurité Sanitaire des Produits de Santé (AFSSAPS) recommends clinical and ultrasound examination every 6 months for women with PIP implants. Any rupture, suspected rupture or leakage of prosthesis should lead to its explantation as well as that of the contralateral implant. In cases of unusual signs of inflammation, histological and immunohistochemical samples are to be taken. PMID:23480085

  3. Thrust faulting and hydrocarbon generation: discussion

    SciTech Connect

    Warner, M.A.; Royse, F.

    1987-07-01

    Following the discovery of large volumes of hydrocarbons in the Cordilleran thrust belt of southwestern Wyoming and northern Utah, Angevine and Turcotte (1983), Edman and Surdam (1984), and Furlong and Edman (1984) discussed the role of thrust faulting in hydrocarbon generation. The authors concluded that overthrusting plays an important or even dominant role in the process of hydrocarbon generation in overthrust terrains. These conclusions may be in error because they are based on a mathematical analysis of thermal and geologic models that have little resemblance to actual thrust-belt geology. In this discussion, the authors discuss shortcomings of the thermal model used in the papers referred to above; emphasize the differences between their model and the geologic facts as they exist in thrust belts in general and in western Wyoming in particular; and caution readers about applying the conclusions based on such a model in the search for hydrocarbons. They contend that the temperature effects of thrust faulting were rather insignificant in the process of hydrocarbon generation in the Wyoming thrust belt.

  4. Discussion of long-range weather prediction

    SciTech Connect

    Canavan, G.H.

    1998-09-10

    A group of scientists at Los Alamos have held a series of discussions of the issues in and prospects for improvements in Long-range Weather Predictions Enabled by Proving of the Atmosphere at High Space-Time Resolution. The group contained the requisite skills for a full evaluation, although this report presents only an informal discussion of the main technical issues. The group discussed all aspects of the proposal, which are grouped below into the headings: (1) predictability; (2) sensors and satellites, (3) DIAL and atmospheric sensing; (4) localized transponders; and (5) summary and integration. Briefly, the group agreed that the relative paucity of observations of the state of the atmosphere severely inhibits the accuracy of weather forecasts, and any program that leads to a more dense and uniform observational network is welcome. As shown in Long-range Weather more dense and uniform observational network is welcome. As shown in Long-range Weather Predictions, the pay-back of accurate long-range forecasts should more than justify the expenditure associated with improved observations and forecast models required. The essential step is to show that the needed technologies are available for field test and space qualification.

  5. Panel Discussion With PR/PRL Editors

    NASA Astrophysics Data System (ADS)

    Blume, Martin

    2002-03-01

    Panelists: Peter Adams, Physical Review B Irwin Oppenheim, Physical Review E & Massachsetts Institute of Technology Jack Sandweiss, Physical Review Letters & Yale University Reinhardt Schuhmann, Physical Review Letters The panel will include Editors from Physical Review Letters, Physical Review B, and Physical Review E. They will briefly discuss some current issues facing the journals, such as raising the standards for PRL acceptance and the role of electronic media attachments (e.g., movies) to journal articles. Opinions on these issues from the audience will be solicited. The Editors will also respond to questions and comments from the audience.

  6. ASPRS Digital Imagery Guideline Image Gallery Discussion

    NASA Technical Reports Server (NTRS)

    Ryan, Robert

    2002-01-01

    The objectives of the image gallery are to 1) give users and providers a simple means of identifying appropriate imagery for a given application/feature extraction; and 2) define imagery sufficiently to be described in engineering and acquisition terms. This viewgraph presentation includes a discussion of edge response and aliasing for image processing, and a series of images illustrating the effects of signal to noise ratio (SNR) on images. Another series of images illustrates how images are affected by varying the ground sample distances (GSD).

  7. [Why should LD be discussed now?].

    PubMed

    Futakami, S

    1999-05-01

    The term learning disability was first used in 1962 by Kirk S A in his textbook. In Japan the term was adopted as a substitute term for MBD in the 1970s. At present many professionals, especially on education and psychology, are interested with LD. The role of child neurologist is discussed here from three viewpoint: the term and definition, LD as a brain dysfunction, and LD in the child neurology. For collaboration with education and psychology, child neurologist should know more about LD and make efforts to find the etiology and mechanism of LD. PMID:10355261

  8. PDII- Additional discussion of the dynamic aperture

    SciTech Connect

    Norman M. Gelfand

    2002-07-23

    This note is in the nature of an addition to the dynamic aperture calculations found in the report on the Proton Driver, FERMILAB-TM-2169. A extensive discussion of the Proton Driver lattice, as well as the nomenclature used to describe it can be found in TM-2169. Basically the proposed lattice is a racetrack design with the two arcs joined by two long straight sections. The straight sections are dispersion free. Tracking studies were undertaken with the objective of computing the dynamic aperture for the lattice and some of the results have been incorporated into TM-2169. This note is a more extensive report of those calculations.

  9. Panel discussion - Phases of the interstellar medium

    NASA Technical Reports Server (NTRS)

    Shull, J. Michael

    1987-01-01

    This article summarizes the panel discussion on 'Phases of the Interstellar Medium'. While the 3-phase model has had many successes, several recent observations disagree with its predictions. The major unresolved issue is whether the model can be 'fixed' by tinkering with cloud geometries and supernova rates and by including a galactic fountain. The Milky Way supernova rate may have been overestimated, many supernovae may be less than 10 to the 51st ergs, and modelers have probably neglected important physics in mass transport, cloud formation and halo input.

  10. Just a routine operation: a critical discussion.

    PubMed

    McClelland, G; Smith, M B

    2016-05-01

    This article has summarised a critical discussion of the human factors that contributed to the death of a patient from a failure to respond appropriately to a 'can't intubate, can't ventilate' scenario. The contributory factors included the clinical team's inability to communicate, prioritise tasks and demonstrate effective leadership and assertive followership. The film Just a routine operation has now been in circulation for several years. When a system is designed and introduced with the intention of making a change to clinical practice, it can quickly become just another component of an organisation's architecture and complacency around its use can develop. This article has been written specifically for perioperative practitioners to renew the debate around the human factors that contribute to patient harm. By critically discussing Just a routine operation and attempting to review why the incident occurred, this article has attempted to emphasise that some of the conditions and behaviours that contributed to the death of Elaine Bromiley may be latent within our organisations and teams, and may continue to contribute to failures that affect patient safety. PMID:27400489

  11. Best Friends’ Discussions of Social Dilemmas

    PubMed Central

    McDonald, Kristina L.; Malti, Tina; Killen, Melanie; Rubin, Kenneth H.

    2013-01-01

    Peer relationships, particularly friendships, have been theorized to contribute to how children and adolescents think about social and moral issues. The current study examined how young adolescent best friends (191 dyads; 53.4% female) reason together about multifaceted social dilemmas and how their reasoning is related to friendship quality. Mutually-recognized friendship dyads were videotaped discussing dilemmas entailing moral, social-conventional and prudential/pragmatic issues. Both dyad members completed a self-report measure of friendship quality. Dyadic data analyses guided by the Actor-Partner Interdependence Model indicated that adolescent and friend's reports of friendship qualities were related to the forms of reasoning used during discussion. Friends who both reported that they could resolve conflicts in a constructive way were more likely to use moral reasoning than friends who reported that their conflict resolution was poor or disagreed on the quality of their conflict resolution. The findings provide evidence for the important role that friendship interaction may play in adolescents’ social and moral development. PMID:23666555

  12. Best friends' discussions of social dilemmas.

    PubMed

    McDonald, Kristina L; Malti, Tina; Killen, Melanie; Rubin, Kenneth H

    2014-02-01

    Peer relationships, particularly friendships, have been theorized to contribute to how children and adolescents think about social and moral issues. The current study examined how young adolescent best friends (191 dyads; 53.4% female) reason together about multifaceted social dilemmas and how their reasoning is related to friendship quality. Mutually-recognized friendship dyads were videotaped discussing dilemmas entailing moral, social-conventional and prudential/pragmatic issues. Both dyad members completed a self-report measure of friendship quality. Dyadic data analyses guided by the Actor-Partner Interdependence Model indicated that adolescent and friend reports of friendship qualities were related to the forms of reasoning used during discussion. Friends who both reported that they could resolve conflicts in a constructive way were more likely to use moral reasoning than friends who reported that their conflict resolution was poor or disagreed on the quality of their conflict resolution. The findings provide evidence for the important role that friendship interaction may play in adolescents' social and moral development. PMID:23666555

  13. Panel Discussion on Multi-Disciplinary Analysis

    NASA Technical Reports Server (NTRS)

    Garcia, Robert

    2002-01-01

    The Marshall Space Flight Center (MSFC) is hosting the Thermal and Fluids Analysis Workshop (TFAWS) during the week of September 10, 2001. Included in this year's TFAWS is a panel session on Multidisciplinary Analysis techniques. The intent is to provide an opportunity for the users to gain information as to what product may be best suited for their applications environment and to provide feedback to you, the developers, on future desired developments. Potential users of multidisciplinary analysis (MDA) techniques are often overwhelmed by the number of choices available to them via commercial products and by the pace of new developments in this area. The purpose of this panel session is to provide a forum wherein MDA tools available and under development can be discussed, compared, and contrasted. The intent of this panel is to provide the end-user with the information necessary to make educated decisions on how to proceed with selecting their MDA tool. It is anticipated that the discussions this year will focus on MDA techniques that couple discipline codes or algorithms (as opposed to monolithic, unified MDA approaches). The MDA developers will be asked to prepare a product overview presentation addressing specific questions provided by the panel organizers. The purpose of these questions will be to establish the method employed by the particular MDA technique for communication between the discipline codes, to establish the similarities and differences amongst the various approaches, and to establish the range of experience and applications for each particular MDA approach.

  14. Accelerating Cleanup: Focus on 2006. Discussion draft

    SciTech Connect

    1997-06-01

    This executive summary addresses the activities associated with the National Transuranic (TRU) Program managed by the Carlsbad Area Office (CAO). The CAO programmatically reports to the Assistant Secretary for Environmental Management and receives administrative support through the Albuquerque Operations Office. The mission of the Carlsbad Area Office (CAO) is to protect human health and the environment by opening and operating the Waste Isolation Pilot Plant for site disposal of TRU waste and by establishing an effective system for management of TRU waste from generation to disposal. It includes personnel assigned to the CAO, the Waste Isolation Pilot Plant (WIPP) site operations, and other activities associated with the National TRU Program. The CAO develops and directs implementation of the program, while the DOE Headquarters establishes policy and guidelines. The CAO assesses compliance with the program guidance, as well as the commonality of activities and assumptions among all the sites. Since the development of the February 28, 1997, database used to develop this Discussion Draft, the opening of the WIPP facility for receipt of Contact Handled waste has been delayed from November 1997 to May 1998. This slippage is significant enough to require a change in the milestones and volumes included in the documents to be reviewed by our stakeholders. Changes have been incorporated into this Discussion Draft and its supporting Project Baseline Summaries (PBSs).

  15. Student decision making in large group discussion

    NASA Astrophysics Data System (ADS)

    Kustusch, Mary Bridget; Ptak, Corey; Sayre, Eleanor C.; Franklin, Scott V.

    2015-04-01

    It is increasingly common in physics classes for students to work together to solve problems and perform laboratory experiments. When students work together, they need to negotiate the roles and decision making within the group. We examine how a large group of students negotiates authority as part of their two week summer College Readiness Program at Rochester Institute of Technology. The program is designed to develop metacognitive skills in first generation and Deaf and hard-of-hearing (DHH) STEM undergraduates through cooperative group work, laboratory experimentation, and explicit reflection exercises. On the first full day of the program, the students collaboratively developed a sign for the word ``metacognition'' for which there is not a sign in American Sign Language. This presentation will focus on three aspects of the ensuing discussion: (1) how the instructor communicated expectations about decision making; (2) how the instructor promoted student-driven decision making rather than instructor-driven policy; and (3) one student's shifts in decision making behavior. We conclude by discussing implications of this research for activity-based physics instruction.

  16. Discussing Health Care Costs with Patients

    PubMed Central

    Hardee, James T; Platt, Frederic W; Kasper, Ilene K

    2005-01-01

    Escalating health care costs are affecting patients across the country. As employers and insurance companies face higher expenses, they may move to a cost-sharing strategy, which potentially increases financial burdens on patients. In this situation, physicians may find themselves serving as both medical and financial advisors for their patients. Clinical encounters in which patients experience financial hardship can be awkward and frustrating for both parties. Physicians must learn to discuss issues of affordability in a manner that builds, rather than detracts, from a therapeutic alliance. This article describes our experiences using several communication skills that can help in the discussion of health care costs with patients. The primary skill, empathic communication, which includes “we” statements and “I wish …” statements, serves to create a platform for shared decision-making, negotiation, and a search for alternatives. In addition, it is helpful if physician offices have resource materials available and strategies identified to assist patients facing financial hardship. PMID:16050867

  17. Test versus analysis: A discussion of methods

    NASA Technical Reports Server (NTRS)

    Butler, T. G.

    1986-01-01

    Some techniques for comparing structural vibration data determined from test and analysis are discussed. Orthogonality is a general category of one group, correlation is a second, synthesis is a third and matrix improvement is a fourth. Advantages and short-comings of the methods are explored with suggestions as to how they can complement one another. The purpose for comparing vibration data from test and analysis for a given structure is to find out whether each is representing the dynamic properties of the structure in the same way. Specifically, whether: mode shapes are alike; the frequencies of the modes are alike; modes appear in the same frequency sequence; and if they are not alike, how to judge which to believe.

  18. Modeling household behavior in developing countries: discussion.

    PubMed

    Quisumbing, A R

    1996-12-01

    A large and growing body of literature has examined how agricultural households cope with risk. Much of the work has focused on which types of households are better able to smooth consumption, testing whether households with more resources and greater access to income-smoothing institutions, such as credit markets or well-functioning labor markets exhibit greater consumption smoothing. However, income shocks may have different effects upon different individuals within households, and differences in individual ability to smooth income or consumption may have welfare consequences which go beyond foregone income. The development of collective household models challenges the assumption that individuals within households maximize a single utility function. The assumption of income pooling has also been rejected in a growing body of empirical research on intrahousehold resource allocation. However, research on risk-pooling within households and differences in individual abilities to smooth consumption is relatively new. Selected papers are discussed. PMID:12292622

  19. Changes to key L8 guidance discussed.

    PubMed

    Mount, Steve

    2014-01-01

    The Legionella Approved Code of Practice and guidance (ACoP) has recently undergone a review by the Health and Safety Executive. Steve Mount BSc (hons) CBiol MIBiol MWMSoc, an independent specialist consultant in water hygiene and safety, reports on the first conference (held in Birmingham) to discuss these changes, entitled 'Legionella management: The revised ACoP (L8); what impact will the changes have on you?'. The event was hosted by Immerse Training, and delegates' views on various issues, including the non-definitive terminology, and their general concerns regarding Legionella management and competence, were recorded, along with the impact that the proposed changes will have on people who manage water systems. PMID:24516938

  20. Discussion of medical x ray picture normalization

    NASA Astrophysics Data System (ADS)

    Wang, Dezong; Xiong, Yingen; Cheng, Liping

    1996-01-01

    There is great significance in comparing medical x-ray pictures, which are taken in different periods. For the orthopaedics surgeon comparing the density of bone is one important way of clinical diagnosis. Some persons think that if these orthopaedics pictures are processed by histogram normalization their gray level and pseudo color can be compared directly. But for one picture we know that the gray distribution is different between the original picture and the processed picture. Comparing these pictures is not authentic. In this paper we discuss that subject and describe the basis of histogram normalization. The distribution on original x-ray pictures and processed pictures is provided. The methods to compare different pictures are mentioned.

  1. Middle Ear Adenoma: Case Report and Discussion

    PubMed Central

    Vrugt, B.; Huber, A. M.

    2014-01-01

    Introduction. Despite modern radiological workup, surgeons can still be surprised by intraoperative findings or by the pathologist's report. Materials & Methods. We describe the case of a 52-year-old male who was referred to our clinic with a single sided conductive hearing loss. He ultimately underwent middle ear exploration and excision of a middle ear tumour followed by second look and ossiculoplasty a year later. Results. Though preoperative CT and MRI scanning were suggestive of a congenital cholesteatoma, the pathologist's report diagnosed a middle ear adenoma. Discussion. Middle ear glandular tumors are extremely rare and, despite numerous histological techniques, continue to defy satisfactory classification. Most surgeons advocate surgical excision though evidence of the tumour's natural course and risk of recurrence is lacking. PMID:25045567

  2. Ice and environment: A terminological discussion

    NASA Astrophysics Data System (ADS)

    Dobinski, Wojciech

    2006-12-01

    This article discusses the terminological and disciplinary problems associated with the point of view that ice is a rock, resulting from a dynamic development of earth sciences which have begun the research into other planets as well. Such a position necessitates a revision of the definitions of the hydrosphere, atmosphere and lithosphere. It is the state that determines which particular sphere ice belongs to. Water is understood to be a triphase substance. As a result permafrost should now include the "cold" layer of polythermal glaciers. Rock glaciers are features that integrate glacial and periglacial permafrost. This facilitates the research into the interaction between the glacial and the periglacial environment by recognizing the leading role of the isotherm 0 °C as the physical feature integrating these fields.

  3. Discussion on ``Teaching the Second Law''

    NASA Astrophysics Data System (ADS)

    Silbey, Robert; Beretta, Gian Paolo; Cengel, Yunus; Foley, Andrew; Gyftopoulos, Elias P.; Hatsopoulos, George N.; Keck, James C.; Lewins, Jeffery; Lior, Noam; Nieuwenhuizen, Theodorus M.; Steinfeld, Jeffrey; von Spakovsky, Michael R.; Wang, Lin-Shu; Zanchini, Enzo

    2008-08-01

    This article reports an open discussion that took place during the Keenan Symposium "Meeting the Entropy Challenge" (held in Cambridge, Massachusetts, on October 5, 2007) following the short presentations—each reported as a separate article in the present volume—by Joseph Smith Jr., Howard Butler, Andrew Foley, Kimberly Hamad-Schifferli, Bernhardt Trout, Jeffery Lewins, Enzo Zanchini, and Michael von Spakovsky. All panelists and the audience were asked to address the following questions • Why is the second law taught in so many different ways? Why so many textbooks on thermodynamics? Why so many schools of thought? • Some say that thermodynamics is limited to equilibrium, others that it extends to nonequilibrium. How is entropy defined for nonequilibrium states?

  4. Discussion of Opportunities in Computational Physics

    NASA Astrophysics Data System (ADS)

    Berg, Bernd; Pederson, Mark

    2011-03-01

    A discussion of the points raised in the previous talk by Mark Pederson (DOE) will be encouraged, including: (1) Identifying models and strategies for effectively organizing and availing complex computational simulation capabilities to a broader scientific and technical community. (2) Identifying cross-discipline communication of capabilities to ensure sharing of algorithms. (3) Opinions on evolution of overlap between the basic energy scientific mission and the fields that are typically represented by the March-Meeting participants. (4) Interactions between the domains of computational physics, computer science, and applied mathematics. (5) The proper balance between individual and group achievement. (6) What role could DCOMP have in this? In part supported by the DOE grant DE-FG02-97ER41022.

  5. Folding with thermal-mechanical feedback: Discussion

    NASA Astrophysics Data System (ADS)

    Treagus, Susan H.; Hudleston, Peter J.

    2009-07-01

    A recent paper in this Journal by Bruce Hobbs, Klaus Regenauer-Lieb and Alison Ord [Hobbs, B., Regenauer-Lieb, K., Ord, A., 2008. Folding with thermal-mechanical feedback. Journal of Structural Geology 30, 1572-1592] presents an alternative theory to the traditional Biot-Ramberg theory for folding of viscous rocks that involves non-equilibrium thermodynamics and thermal-mechanical feedback. The authors convey a strong message throughout their paper that the folds produced by this theoretical and numerical modelling are geologically realistic and provide a better explanation for many natural folds than the traditional theory. They promise the same approach for boudinage, and present this folding paper as part of a "unified framework for rock deformation processes". Readers of the Journal of Structural Geology might be led to conclude that this paper provides a good alternative model for folding of rocks. Our discussion will disagree, on four counts.

  6. Comparing Asynchronous Online Discussions and Face-to-Face Discussions in a Classroom Setting

    ERIC Educational Resources Information Center

    Wang, Qiyun; Woo, Huay Lit

    2007-01-01

    The purpose of this study is to investigate the perceived differences between asynchronous online discussions and face-to-face discussions in a classroom setting. The students' reflections were analysed by following a qualitative research approach. The results showed that atmosphere, response, efficiency, interactivity and communication were the…

  7. Does the Discussion Help? The Impact of a Formally Assessed Online Discussion on Final Student Results

    ERIC Educational Resources Information Center

    Palmer, Stuart; Holt, Dale; Bray, Sharyn

    2008-01-01

    While there is agreement that participation in online asynchronous discussions can enhance student learning, it has also been identified that there is a need to investigate the impact of participation in online discussions on student course performance. This paper presents a case study based on an undergraduate engineering management unit…

  8. Designing a Discussion Environment to Enhance Connectivity and Sustainability in Asynchronous Online Discussion

    ERIC Educational Resources Information Center

    Gao, Fei

    2011-01-01

    Lack of connectivity and sustainability are two common problems in asynchronous online discussions. In this paper, the author proposes that the two problems may have to do with the structure of threaded forums, that is, the design of threaded forums may constrain participants from having well-connected and sustained discussions. A new discussion…

  9. Improving Student Discussions in Graduate and Undergraduate Courses: Transforming the Discussion Leader

    ERIC Educational Resources Information Center

    Soranno, Patricia A.

    2010-01-01

    Student discussions are a common teaching approach in graduate and advanced undergraduate courses because of their benefits to student learning, and to future professional development for natural resources professionals. However, traditional student-led discussions often are ineffective at meeting course and learning objectives and suffer from…

  10. Science in Discussions: An Analysis of the Use of Science Content in Socioscientific Discussions

    ERIC Educational Resources Information Center

    Nielsen, Jan Alexis

    2012-01-01

    This paper presents a normative pragmatics analysis of students' use of science content in eight socioscientific group discussions about human gene therapy. The specific focus of the paper is on the argumentative role that invocations of science had in the dialectics of the discussions. The analysis suggests that science content occasionally…