Science.gov

Sample records for 345-kv transmission tie

  1. Venue-Mediated Weak Ties in Multiplex HIV Transmission Risk Networks Among Drug-Using Male Sex Workers and Associates

    PubMed Central

    Wang, Peng; Ross, Michael W.; Williams, Mark L.

    2015-01-01

    Objectives. We investigated the structural characteristics of a multiplex HIV transmission risk network of drug-using male sex workers and their associates. Methods. Using a sample of 387 drug-using male sex workers and their male and female associates in Houston, Texas, we estimated an exponential random graph model to examine the venue-mediated relationships between individuals, the structural characteristics of relationships not linked to social venues, and homophily. We collected data in 2003 to 2004. The network comprised social, sexual, and drug-using relationships and affiliations with social venues. Results. Individuals affiliated with the same social venues, bars, or street intersections were more likely to have nonreciprocated (weak) ties with others. Sex workers were less likely than were other associates to have reciprocated (strong) ties to other sex workers with the same venues. Individuals tended to have reciprocated ties not linked to venues. Partner choice tended to be predicated on homophily. Conclusions. Social venues may provide a milieu for forming weak ties in HIV transmission risk networks centered on male sex workers, which may foster the efficient diffusion of prevention messages as diverse information is obtained and information redundancy is avoided. PMID:25880956

  2. Tied Up

    USGS Multimedia Gallery

    The Canadian Coast Guard Ship Louis S. St-Laurent ties up to the Coast Guard Cutter Healy in the Arctic Ocean Sept. 5, 2009. The two ships are taking part in a multi-year, multi-agency Arctic survey that will help define the Arctic continental shelf....

  3. Environmental Assessment for Central Power and Light Company`s proposed Military Highway-CFE tie 138/69-kV transmission line project Brownsville, Cameron County, Texas

    SciTech Connect

    Not Available

    1992-04-01

    Central Power and Light Company (CPL) intends to upgrade its existing transmission line ties with the Commision Federal de Electricidad (CFE) system in Mexico. CPL currently has a single 69-kilovolt (kV) transmission line in the Brownsville area which connects CPL`s system with the system of CFE. This existing line runs between the Brownsville Switching Station, located on Laredo Road in Brownsville, Cameron County, Texas, and an existing CFE 69-kV line at the Rusteberg Bend of the Rio Grande in Cameron County. Under current conditions of need, the existing 69-kV line does not possess sufficient capability to engage in appropriate power exchanges. Therefore, CPL is proposing to build a new line to link up with CFE. This proposed line would be a double-circuit line, which would (1) continue (on a slightly relocated route) the existing 69-kV tie from CPL`s Brownsville Switching Station to CFE`s facilities, and (2) add a 138-kV tie from the Military Highway Substation, located on Military Highway (US Highway 281), to CFE`s facilities. The proposed 138/69-kV line, which will be constructed and operated by CPL, will be built primarily on steel single-pole structures within an average 60-foot (ft) wide right-of-way (ROW). It will be approximately 6900--9200 ft (1.3--1.7 miles) in length, depending on the alternative route constructed.

  4. Networks of strong ties

    NASA Astrophysics Data System (ADS)

    Shi, Xiaolin; Adamic, Lada A.; Strauss, Martin J.

    2007-05-01

    Social networks transmitting covert or sensitive information cannot use all ties for this purpose. Rather, they can only use a subset of ties that are strong enough to be “trusted”. This paper addresses whether it is still possible, under this restriction, for information to be transmitted widely and rapidly in social networks. We use transitivity as evidence of strong ties, requiring one or more shared contacts in order to count an edge as strong. We examine the effect of removing all non-transitive ties in two real social network data sets, imposing varying thresholds in the number of shared contacts. We observe that transitive ties occupy a large portion of the network and that removing all other ties, while causing some individuals to become disconnected, preserves the majority of the giant connected component. Furthermore, the average shortest path, important for the rapid diffusion of information, increases only slightly relative to the original network. We also evaluate the cost of forming transitive ties by modeling a random graph composed entirely of closed triads and comparing its connectivity and average shortest path with the equivalent Erdös-Renyi random graph. Both the empirical study and random model point to a robustness of strong ties with respect to the connectivity and small world property of social networks.

  5. The Strength of Varying Tie Strength

    E-print Network

    Bruggeman, Jeroen

    2012-01-01

    "The Strength of Weak Ties" argument (Granovetter 1973) says that the most valuable information is best collected through bridging ties with other social circles than one's own, and that those ties tend to be weak. Aral and Van Alstyne (2011) added that to access complex information, actors need strong ties ("high bandwidth") instead. These insights I generalize by pointing at actors' interest to avoid spending large resources on low value information. Weak ties are well-suited for relatively simple information at low transmission and tie maintenance costs, whereas for complex information, the best outcomes are expected for those actors who vary their bandwidths along with the value of information accessed. To support my claim I use all patents in the USA (two million) over the period 1975-1999. I also show that in rationalized fields, such as technology, bandwidth correlates highly with the value of information, which provides support for using this proxy if value can't be measured directly. Finally, I show ...

  6. Tree-Ties.

    ERIC Educational Resources Information Center

    Gresczyk, Rick

    Created to help students understand how plants were used for food, for medicine, and for arts and crafts among the Ojibwe (Chippewa) Indians, the game Tree-Ties combines earth and social sciences within a specific culture. The game requires mutual respect, understanding, and agreement to succeed. Sounding like the word "treaties", the title is a…

  7. Transmission

    SciTech Connect

    Sugano, K.

    1988-12-27

    A transmission is described which consists of: an input shaft; an output shaft; a first planetary gear set including a first sun gear selectively connectable by a first clutch to the input shaft, a first carrier selectively connectable by a second clutch to the input shaft and a first ring gear connected to the output shaft. The first sun gear selectively held stationary by a first brake, the first carrier is allowed to rotate in the same forward direction as the input shaft when the second clutch is engaged, but prevented from rotating in a reverse direction opposite to the forward direction by a first one-way clutch, the first carrier being selectively held stationary by a second brake; a second planetary gear set including a second sun gear connected to the input shaft, a second carrier connected to the first ring gear and also the the output shaft, and a second ring gear.

  8. Drum tie-down apparatus

    DOEpatents

    Morse, Harvey E. (Albuquerque, NM)

    1984-01-01

    A drum tie-down apparatus for securing drum-like containers in an upright position to a floor or platform of a transportation vehicle having spaced apart cargo tie-down points. The apparatus comprises a pair of cylindrical, hollow tube segments horizontally oriented and engageable with a drum lid adjacent opposite rim edges, flexible strap segments for connecting upper and lower central portions of the tube segments together across the drum lid and a pair of elongated flexible tie-down segments, one extending horizontally through each of the tube segments, the ends thereof being attached to said spaced apart tie-down points such that end portions of the pair of tie-down segments extend downwardly and radially outwardly from the tube segments to the tie-down points.

  9. Draft environmental impact statement for construction and operation of the proposed Bangor Hydro-Electric Company`s second 345-kV transmission tie line to New Brunswick

    SciTech Connect

    1993-10-01

    This Draft Environmental Impact Statement (DEIS) was prepared by the US Department of Energy (US DOE). The proposed action is the issuance of Presidential Permit PP-89 by DOE to Bangor Hydro-Electric Company to construct and operate a new international transmission line interconnection to New Brunswick, Canada that would consist of an 83.8 mile (US portion), 345-kilovolt (kV) alternating current transmission line from the US-Canadian border at Baileyville, Maine to an existing substation at Orrington, Maine. The principal environmental impacts of the construction and operation of the transmission line would be incremental in nature and would include the conversion of forested uplands (mostly commercial timberlands) and wetlands to right-of-way (small trees, shrubs, and herbaceous vegetation). The proposed line would also result in localized minor to moderate visual impacts and would contribute a minor incremental increase in the exposure of some individuals to electromagnetic fields. This DEIS documents the purpose and need for the proposed action, describes the proposed action and alternatives considered and provides a comparison of the proposed and alternatives routes, and provides detailed information on analyses of the environmental consequences of the proposed action and alternatives, as well as mitigative measures to minimize impacts.

  10. Roles of Ties in Spreading

    E-print Network

    Cui, Ai-Xiang; Zhou, Tao

    2012-01-01

    Background: Controlling global epidemics in the real world and accelerating information propagation in the artificial world are of great significance, which have activated an upsurge in the studies on networked spreading dynamics. Lots of efforts have been made to understand the impacts of macroscopic statistics (e.g., degree distribution and average distance) and mesoscopic structures (e.g., communities and rich clubs) on spreading processes while the microscopic elements are less concerned. In particular, roles of ties are not yet clear to the academic community. Methodology/Principle Findings: Every edges is stamped by its strength that is defined solely based on the local topology. According to a weighted susceptible-infected-susceptible model, the steady-state infected density and spreading speed are respectively optimized by adjusting the relationship between edge's strength and spreading ability. Experiments on six real networks show that the infected density is increased when strong ties are favored i...

  11. InGaAs-based bow-tie diode for spectroscopic terahertz imaging

    NASA Astrophysics Data System (ADS)

    Kašalynas, I.; Venckevi?ius, R.; Seliuta, D.; Grigelionis, I.; Valušis, G.

    2011-12-01

    Suitability of InGaAs-based bow-tie diodes for a spectroscopic terahertz imaging is demonstrated by inspecting explosive simulators packed in a thick plastic container. The transmission images were obtained within the frequency range of 0.58-2.52 THz at room temperature using optimized bow-tie diode connection scheme. Content of sucrose and tartaric acid in the test samples was discriminated. Measured absorbance was found to be in a good correlation with Fourier spectroscopy data. Performance of room temperature THz imaging using the bow-tie diode was compared versus a commercial pyro-electric sensor.

  12. Changing Views on Intergenerational Ties

    PubMed Central

    Fingerman, Karen L.; Sechrist, Jori; Birditt, Kira

    2015-01-01

    Ties to parents or grown children may be the most important social relationships in an adult’s life. Research examining intergenerational relationships has focused on three broader topics: (a) the strength of emotional bonds, (b) exchanges of social support, and (c) the effects of the relationship on individual well-being. This review considers some of the major theoretical developments in the field including solidarity and intergenerational ambivalence theory as well as the newly developed multidimensional model of support. We also consider weaknesses in the research and theories to date and provide suggestions for future research. PMID:23037718

  13. Peru turnaround tied to privatization

    SciTech Connect

    Not Available

    1993-04-19

    Petroleos del Peru predicts a 10% increase in Peru's oil production this year and a further increase in 1994. Petroperu also forecasts a sharp increase in drilling in Peru this year. After several years of declining oil production, a gradual turnaround in the cash strapped country's petroleum industry is largely tied to its progress in privatization. The government last year began a campaign to privatize all state owned companies by the end of July 1995. The paper discusses forecasts by Petroperu; the contract of Occidental del Amazonas Inc.; the Petromar privatization; Great Western's contract; development of the Aguaytia gas field; and refinery contracts.

  14. The relationship between discrimination and high-risk social ties by race/ethnicity: examining social pathways of HIV risk.

    PubMed

    Crawford, Natalie D; Galea, Sandro; Ford, Chandra L; Latkin, Carl; Link, Bruce G; Fuller, Crystal

    2014-02-01

    High-risk social ties portend differences in opportunity for HIV exposures and may contribute to racial/ethnic disparities in HIV transmission. Discrimination may affect the formation of high-risk social ties and has not been explored as a possible explanation for these persistent disparities. Using data from injection and non-injection drug users, we examined the association between the number of high-risk sex and drug ties with discrimination due to race, drug use, and incarceration stratified by race/ethnicity. Negative binomial regression models were used. While blacks had significantly fewer injecting ties than Latinos and whites, blacks who reported racial discrimination compared to blacks who did not, had more sex and injecting ties. Latinos who reported drug use discrimination compared to Latinos who did not also had more sex ties. Latinos and whites who reported drug use discrimination had more injecting ties than Latinos and whites who did not. Discrimination is associated with high-risk social ties among all racial/ethnic groups. But, these data highlight different forms of discrimination within racial/ethnic group are associated with risky social ties. More research is needed to confirm these findings and further explore the association between various forms of discrimination and social ties that may help explain racial/ethnic disparities in HIV. PMID:23749458

  15. Biomechanical assessment of three rebar tying techniques.

    PubMed

    Albers, James T; Hudock, Stephen D

    2007-01-01

    The National Institute for Occupational Safety and Health (NIOSH) conducted a study of ironworkers to evaluate their risk for developing back and hand injuries from hand-tying reinforcing steel bar and to investigate whether power tying tools can be an effective intervention for the prevention of work-related musculoskeletal disorders. A field investigation of biomechanical loading when using 3 techniques to tie together rebar was conducted. Researchers measured employees' wrist and forearm movement with goniometers and videotaped and analyzed trunk postures. Manually tying rebar at ground level involved sustained deep trunk bending and rapid, repetitive, and forceful hand-wrist and forearm movements. Using a power tier significantly reduced the hand-wrist and forearm movements and allowed the ironworkers to use one free hand to support their trunk posture while tying. Adding an extension handle to the power tier allowed the ironworkers to tie rebar while standing erect, minimizing sustained trunk flexion. PMID:17888237

  16. The Lincoln Tied-Mixture HMM

    E-print Network

    The Lincoln Continuous Tied-Mixture HMM Speech Recognizer* Douglas B. Paul Lincoln Laboratory, MIT or Gaussian mixture pdf per state to tied mixtures in which a single set of Gaus- sians is shared between all states. There were some initial difficulties caused by the use of mixture pruning [12] but these were

  17. Software With Strong Ties to Space

    NASA Technical Reports Server (NTRS)

    2003-01-01

    TieFlow is a simple but powerful business process improvement solution. It can automate and simplify any generic or industry-specific work process, helping organizations to transform work inefficiencies and internal operations involving people, paper, and procedures into a streamlined, well-organized, electronicbased process. TieFlow increases business productivity by improving process cycle times. The software can expedite generic processes in the areas of product design and development, purchase orders, expense reports, benefits enrollment, budgeting, hiring, and sales. It can also shore up vertical market processes such as claims processing, loan application and processing, health care administration, contract management, and advertising agency traffic. The processes can be easily and rapidly captured in a graphical manner and enforced together with rules pertaining to assignments that need to be performed. Aside from boosting productivity, TieFlow also reduces organizational costs and errors. TieFlow was developed with Small Business Innovation Research (SBIR) assistance from Johnson. The SBIR support entitles all Federal Government agencies to utilize the TieFlow software technology free of charge. Tietronix emphasizes that TieFlow is an outstanding workflow resource that could produce dramatic productivity and cost improvements for all agencies, just as it has done and continues to do for NASA. The Space Agency is currently using the software throughout several mission-critical offices, including the Mission Operations Directorate and the Flight Director s Office, for worldwide participation of authorized users in NASA processes. At the Flight Director s Office, TieFlow allows personnel to electronically submit and review changes to the flight rules carried out during missions.

  18. The Navigability of Strong Ties: Small Worlds, Tie Strength, and Network Topology

    E-print Network

    White, Douglas R.

    The Navigability of Strong Ties: Small Worlds, Tie Strength, and Network Topology Self requires navigability. This was the property investigated in the first small world experiment by Travers closer, geographically or occupation- ally, to the target. The problem of navigability is whether

  19. CONFIDENCE INTERVALS FOR POPULATION RANKS IN THE PRESENCE OF TIES AND NEAR TIES

    E-print Network

    Xie, Minge

    of unknown parameter values 1, . . . , k. The conventional frequentist definition of the population rankCONFIDENCE INTERVALS FOR POPULATION RANKS IN THE PRESENCE OF TIES AND NEAR TIES Minge Xie, Kesar Singh and Cun-Hui Zhang Abstract Frequentist confidence intervals for population ranks

  20. A matched Bow-tie antenna at 433MHz for use in underwater wireless sensor networks

    NASA Astrophysics Data System (ADS)

    Abdou, A. A.; Shaw, A.; Mason, A.; Al-Shamma'a, A.; Cullen, J.; Wylie, S.; Diallo, M.

    2013-06-01

    Electromagnetic (EM) wave propagation underwater is been disregarded because of attenuation at high frequencies, however the theory predicts that propagation is possible at some useful distance in the lower Industrial, Scientific and Medical (ISM) band. Common transceivers rely on narrowband antennas and matching circuit. The aim of this paper is to design a broadband 433MHz bow-tie antenna and experiment it in air and water without a matching circuit. This antenna could be attached to wireless transceivers and form a Wireless Sensor Network for deployment in various underwater applications. The bow-tie antennas were designed, simulated and constructed in laboratory. Experiments were setup carefully by using a completely isolated transmitter from electronics to avoid airborne transmission. The 433MHz. bow-tie proved its suitability for use in Underwater.

  1. 78 FR 75545 - Prestressed Concrete Steel Rail Tie Wire From the People's Republic of China: Preliminary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ...Administration [A-570-990] Prestressed Concrete Steel Rail Tie Wire From the People's...preliminarily determines that prestressed concrete steel rail tie wire (``PC tie wire...suitable for use as prestressed tendons in concrete railroad ties (``PC tie...

  2. Inferring Tie Strength from Online Directed Behavior

    PubMed Central

    Jones, Jason J.; Settle, Jaime E.; Bond, Robert M.; Fariss, Christopher J.; Marlow, Cameron; Fowler, James H.

    2013-01-01

    Some social connections are stronger than others. People have not only friends, but also best friends. Social scientists have long recognized this characteristic of social connections and researchers frequently use the term tie strength to refer to this concept. We used online interaction data (specifically, Facebook interactions) to successfully identify real-world strong ties. Ground truth was established by asking users themselves to name their closest friends in real life. We found the frequency of online interaction was diagnostic of strong ties, and interaction frequency was much more useful diagnostically than were attributes of the user or the user’s friends. More private communications (messages) were not necessarily more informative than public communications (comments, wall posts, and other interactions). PMID:23300964

  3. TIE: An Ability Test of Emotional Intelligence

    PubMed Central

    ?mieja, Magdalena; Orzechowski, Jaros?aw; Stolarski, Maciej S.

    2014-01-01

    The Test of Emotional Intelligence (TIE) is a new ability scale based on a theoretical model that defines emotional intelligence as a set of skills responsible for the processing of emotion-relevant information. Participants are provided with descriptions of emotional problems, and asked to indicate which emotion is most probable in a given situation, or to suggest the most appropriate action. Scoring is based on the judgments of experts: professional psychotherapists, trainers, and HR specialists. The validation study showed that the TIE is a reliable and valid test, suitable for both scientific research and individual assessment. Its internal consistency measures were as high as .88. In line with theoretical model of emotional intelligence, the results of the TIE shared about 10% of common variance with a general intelligence test, and were independent of major personality dimensions. PMID:25072656

  4. Astrophysics of Reference Frame Tie Objects

    NASA Technical Reports Server (NTRS)

    Johnston, Kenneth J.; Boboltz, David; Fey, Alan Lee; Gaume, Ralph A.; Zacharias, Norbert

    2004-01-01

    The Astrophysics of Reference Frame Tie Objects Key Science program will investigate the underlying physics of SIM grid objects. Extragalactic objects in the SIM grid will be used to tie the SIM reference frame to the quasi-inertial reference frame defined by extragalactic objects and to remove any residual frame rotation with respect to the extragalactic frame. The current realization of the extragalactic frame is the International Celestial Reference Frame (ICRF). The ICRF is defined by the radio positions of 212 extragalactic objects and is the IAU sanctioned fundamental astronomical reference frame. This key project will advance our knowledge of the physics of the objects which will make up the SIM grid, such as quasars and chromospherically active stars, and relates directly to the stability of the SIM reference frame. The following questions concerning the physics of reference frame tie objects will be investigated.

  5. Chemical topology: Tying up some loose ends

    NASA Astrophysics Data System (ADS)

    Fenlon, Edward E.

    2010-03-01

    A linear molecule containing three bipyridine ligands can be wrapped around a single metal-ion template to form an open-knot complex. The loose ends of the knot can be 'tied' together through esterification or olefin-metathesis reactions to form closed knots that do not unravel when the metal template is removed.

  6. Laser Vibrometer For Tie Bar Vibration Studies

    NASA Astrophysics Data System (ADS)

    Forsey, R. C.; Watson, A. G.

    1989-07-01

    An optical displacement transducer using pulsed laser light and a triangulation principle has been developed to measure the lateral vibration of Advanced Gas-cooled Reactor (AGR) fuel stringer tie bars in a laboratory pressurised flow rig. Three pairs of orthogonally mounted units provide positional data to a resolution of < lO?m in the frequency range 0-600Hz.

  7. TIES Project Extranet Kick-off Meeting

    E-print Network

    MEETING Extranet objectives · To know the status of project activities & deliverables · To share documents · To share opinions · To have partners contact details · To update the website · All in one place #12;TIES · Latest Documents in download area · Latest messages ­ System messages ­ Forum messages ­ User to user

  8. Real Time Pricing Tie Line Control: A Case Study 

    E-print Network

    Childress, R.

    1999-01-01

    A Tie Line Control System maintains the purchase quantity of electrical energy an industrial facility buys from a utility company. Implementing an advanced Tie Line Control system automates the buy versus make decision process for an industrial...

  9. 4. VIEW OF SOUTHEAST CORNER OF LITTLE FALLS TIE LINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW OF SOUTHEAST CORNER OF LITTLE FALLS TIE LINE TOWER NO. 41, OSPREY NEST ON TOWER TOP. LOOKING NORTHWEST. - Little Falls Tie Line Towers, Near Little Dam Falls on Spokane River, Wellpinit, Stevens County, WA

  10. 2. VIEW OF WEST ELEVATION OF LITTLE FALLS TIE LINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW OF WEST ELEVATION OF LITTLE FALLS TIE LINE TOWER NO. 23, OSPREY NEST ON TOWER TOP. LOOKING EAST - Little Falls Tie Line Towers, Near Little Dam Falls on Spokane River, Wellpinit, Stevens County, WA

  11. Coupling Human Mobility and Social Ties

    E-print Network

    Toole, Jameson L; Schneider, Christian M; Gonzalez, Marta C

    2015-01-01

    Studies using massive, passively data collected from communication technologies have revealed many ubiquitous aspects of social networks, helping us understand and model social media, information diffusion, and organizational dynamics. More recently, these data have come tagged with geographic information, enabling studies of human mobility patterns and the science of cities. We combine these two pursuits and uncover reproducible mobility patterns amongst social contacts. First, we introduce measures of mobility similarity and predictability and measure them for populations of users in three large urban areas. We find individuals' visitations patterns are far more similar to and predictable by social contacts than strangers and that these measures are positively correlated with tie strength. Unsupervised clustering of hourly variations in mobility similarity identifies three categories of social ties and suggests geography is an important feature to contextualize social relationships. We find that the composi...

  12. Chord, Tie Bar & Crossbracing Joint Detail in Plan; Crossbracing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Chord, Tie Bar & Crossbracing Joint Detail in Plan; Crossbracing Center Joint Detail in Plan; Chord Joining Detail in Plan & Elevation; Chord, Panel Post, Tie Bar, & Diagonal Brace Joint Detail; Crossbracing Center Joint Detail in Section; Chord, Panel Post, Tie Bar & Horizontal Brace Joint Detail - Narrows Bridge, Spanning Sugar Creek at Old County Road 280 East, Marshall, Parke County, IN

  13. Bioabsorbable thread for tight tying of bones.

    PubMed

    Hattori, K; Tomita, N; Tamai, S; Ikada, Y

    2000-01-01

    The purpose of this research was to develop a bioabsorbable thread for tight fixation of fractured bones and to examine its mechanical performance in an in-vitro simulation study. The thread is a blend of bioabsorbable poly(L-lactic acid); (PLLA) and poly(epsilon-caprolactone); (PCL) fibers and can be tightly connected by fusion welding of the PCL fibers. The tying strength of the PLLA-PCL blend thread was 39.7 N, which was comparable to that of stainless steel wire. A testing machine was fabricated to measure the fatigue strength of the tying by simulating bone fixation. The results showed that metal wires always failed because of breakage within 25,000 loading cycles, whereas the blend threads did not fail until 50,000 loading cycles. The looseness of tying for simulated bone fixation by the blend thread was within 1mm even after 50 000 loading cycles. In-vivo testing using rats revealed that the blend thread did not cause any severe inflammatory reaction. PMID:10664440

  14. Modeling Social Ties and Household Mobility.

    PubMed

    Metcalf, Sara S

    2014-01-01

    Underlying the aggregate phenomena of persistent problems such as urban sprawl and spatial socio-economic disparity is the individual choice of where to live. This study develops an agent-based model to simulate social and economic influences on neighborhood choice. With Danville, Illinois as an empirical context, a pattern-oriented approach is employed to examine the role of social ties in shaping intra-urban household mobility. In the model, household agents decide whether and where to relocate within the community based upon factors such as neighborhood attractiveness, affordability, and the density of a household's social network in the prospective block group. Social network and neighborhood choices are encoded with logit utility functions. The relative influence of factors affecting the formation of social ties in the simulated social network, such as geographic proximity, similarity of income, race, and presence of children, are adjusted using parameter variation to create alternative model settings. Simulated migration patterns resulting from different network and neighborhood choice coefficients are compared with observed migration patterns over a two-year period. Based upon 1000 simulation experiments, a regression of homeowner migration error (the difference between simulated and observed migration) relative to the parameter settings revealed components of social network choice such as income, race, and probability of local ties to be significant in matching observed migration patterns. A non-linear effect of simulated social networks on household mobility and thus migration error was exhibited in this study. PMID:25035520

  15. Grid-Tied Photovoltaic Power System

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2011-01-01

    A grid-tied photovoltaic (PV) power system is connected directly to the utility distribution grid. Facility power can be obtained from the utility system as normal. The PV system is synchronized with the utility system to provide power for the facility, and excess power is provided to the utility. Operating costs of a PV power system are low compared to conventional power technologies. This method can displace the highest-cost electricity during times of peak demand in most climatic regions, and thus reduce grid loading. Net metering is often used, in which independent power producers such as PV power systems are connected to the utility grid via the customers main service panels and meters. When the PV power system is generating more power than required at that location, the excess power is provided to the utility grid. The customer pays the net of the power purchased when the on-site power demand is greater than the onsite power production, and the excess power is returned to the utility grid. Power generated by the PV system reduces utility demand, and the surplus power aids the community. Modern PV panels are readily available, reliable, efficient, and economical, with a life expectancy of at least 25 years. Modern electronics have been the enabling technology behind grid-tied power systems, making them safe, reliable, efficient, and economical with a life expectancy equal to the modern PV panels. The grid-tied PV power system was successfully designed and developed, and this served to validate the basic principles developed, and the theoretical work that was performed. Grid-tied PV power systems are reliable, maintenance- free, long-life power systems, and are of significant value to NASA and the community. Of particular value are the analytical tools and capabilities that have been successfully developed. Performance predictions can be made confidently for grid-tied PV systems of various scales. The work was done under the NASA Hybrid Power Management (HPM) Program, which is the integration of diverse power devices in an optimal configuration for space and terrestrial applications.

  16. Coupling human mobility and social ties.

    PubMed

    Toole, Jameson L; Herrera-Yaqüe, Carlos; Schneider, Christian M; González, Marta C

    2015-04-01

    Studies using massive, passively collected data from communication technologies have revealed many ubiquitous aspects of social networks, helping us understand and model social media, information diffusion and organizational dynamics. More recently, these data have come tagged with geographical information, enabling studies of human mobility patterns and the science of cities. We combine these two pursuits and uncover reproducible mobility patterns among social contacts. First, we introduce measures of mobility similarity and predictability and measure them for populations of users in three large urban areas. We find individuals' visitations patterns are far more similar to and predictable by social contacts than strangers and that these measures are positively correlated with tie strength. Unsupervised clustering of hourly variations in mobility similarity identifies three categories of social ties and suggests geography is an important feature to contextualize social relationships. We find that the composition of a user's ego network in terms of the type of contacts they keep is correlated with mobility behaviour. Finally, we extend a popular mobility model to include movement choices based on social contacts and compare its ability to reproduce empirical measurements with two additional models of mobility. PMID:25716185

  17. Strong Ties, Weak Ties, and Human Capital: Latino Immigrant Employment outside the Enclave

    ERIC Educational Resources Information Center

    Pfeffer, Max J.; Parra, Pilar A.

    2009-01-01

    This study focuses on the role of social ties and human capital in the integration of Latino immigrants into the local economy. This analysis extends earlier research by focusing on more rural contexts with limited labor-market opportunities and less access to social resources provided by coethnics. We reconsider conclusions of previous studies by…

  18. Failure of expansion joint tie rods -- Impact on bellows integrity

    SciTech Connect

    Daugherty, W.L.; Miller, R.F.

    1992-01-01

    Expansion joints are used in piping systems to accomodate pipe deflections during service and to facilitate fitup. Often, tie rods are employed to limit the range of axial deflection. Additional restraint against excessive displacement can be provided by the surrounding pipe and associated supports. This paper presents a methodology that was employed to estimate the consequences of tie rod failure. Of particular interest is whether tie rod failure can lead to sufficient displacement as to cause bellows rupture.

  19. Failure of expansion joint tie rods -- Impact on bellows integrity

    SciTech Connect

    Daugherty, W.L.; Miller, R.F.

    1992-12-31

    Expansion joints are used in piping systems to accomodate pipe deflections during service and to facilitate fitup. Often, tie rods are employed to limit the range of axial deflection. Additional restraint against excessive displacement can be provided by the surrounding pipe and associated supports. This paper presents a methodology that was employed to estimate the consequences of tie rod failure. Of particular interest is whether tie rod failure can lead to sufficient displacement as to cause bellows rupture.

  20. 27 CFR 6.72 - “Tie-in” sales.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false âTie-inâ sales. 6.72 Section 6.72 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS âTIED-HOUSEâ Unlawful Inducements Quota Sales § 6.72 “Tie-in” sales. The act by an industry member of requiring that...

  1. 27 CFR 6.72 - “Tie-in” sales.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false âTie-inâ sales. 6.72 Section 6.72 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS âTIED-HOUSEâ Unlawful Inducements Quota Sales § 6.72 “Tie-in” sales. The act by an industry member of requiring that...

  2. 78 FR 75544 - Prestressed Concrete Steel Rail Tie Wire From Mexico: Preliminary Determination of Sales at Less...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ...Administration [A-201-843] Prestressed Concrete Steel Rail Tie Wire From Mexico: Preliminary...preliminarily determines that prestressed concrete steel rail tie wire (``PC tie wire...suitable for use as prestressed tendons in concrete railroad ties (``PC tie...

  3. ConnecTied Documentation www.connectied.com

    E-print Network

    Hamblen, James

    ConnecTied Documentation www.connectied.com Physical WorldComputing World #12;ECE 4180 Project............................................................................................................................... 2 3. Development........................................................................................................................ 3 3.1 Marker Detection

  4. Evaluation of Specialized Laparoscopic Suturing and Tying Devices

    PubMed Central

    Madan, Atul K.; Tebbit, Christopher L.; Park, William C.; Kumari, Nakka V. Aruna; Shervin, Nina

    2004-01-01

    Background: Laparoscopic suturing and tying constitute advanced minimally invasive surgery skills. Developing proficiency in the standard methods with needle drivers is often an arduous process. Recent advances in laparoscopic instrumentations has allowed for easier methods of suturing and tying. This study investigated the hypothesis that the use of a specialized suturing device and a specialized tying device allows inexperienced medical students to suture and tie laparoscopically. Methods: Preclinical medical students who had not received any training in open or laparoscopic surgery were included in this investigation. Each student was given a 5-minute demonstration of a specialized suturing device and a specialized tying device. The medical students were not allowed to deploy either device before actual use. After the demonstration, each student was given the device to use in a porcine model. Times were recorded and a subjective grade was given for each student. Results: Twenty medical students were involved in this study. All medical students were able to complete the task of suturing and tying. The average time to suture was 104.6 seconds and the average time to tying was 31.2 seconds. The average subjective performance grade was 90 (out of 100). Conclusion: Specialized devices are easy to learn and use for laparoscopic suturing and tying with minimal instruction even for inexperienced medical students. Even surgeons who are not well versed in laparoscopic surgery should be able to suture and tie with certain laparoscopic instruments. PMID:15119669

  5. BSE Rap: intergenerational ties to save lives.

    PubMed

    Ehmann, J L

    1993-09-01

    This article presents an innovative public-education strategy that was created to promote breast health awareness and early breast cancer detection among minority and low-income adolescent females. Given the importance of teaching breast self-examination (BSE), program development focused on creation of the BSE Rap, a lively music-video presentation. Increasing adolescents' knowledge and awareness of BSE is viewed as a springboard for disseminating information to their mothers and grandmothers. Funding was obtained for production of a video and a breast health diary, which are the program's key components. Marketing strategies included contacts with community organizations and healthcare professionals. Program evaluations reveal that the BSE Rap serves as a positive motivator for participants to discuss BSE and mammography with their mothers and grandmothers. The BSE Rap offers oncology nurses the opportunity to save lives using a unique and creative tool that focuses on intergenerational ties. PMID:8415152

  6. Evolution of Bow-Tie Architectures in Biology

    PubMed Central

    Friedlander, Tamar; Mayo, Avraham E.; Tlusty, Tsvi; Alon, Uri

    2015-01-01

    Bow-tie or hourglass structure is a common architectural feature found in many biological systems. A bow-tie in a multi-layered structure occurs when intermediate layers have much fewer components than the input and output layers. Examples include metabolism where a handful of building blocks mediate between multiple input nutrients and multiple output biomass components, and signaling networks where information from numerous receptor types passes through a small set of signaling pathways to regulate multiple output genes. Little is known, however, about how bow-tie architectures evolve. Here, we address the evolution of bow-tie architectures using simulations of multi-layered systems evolving to fulfill a given input-output goal. We find that bow-ties spontaneously evolve when the information in the evolutionary goal can be compressed. Mathematically speaking, bow-ties evolve when the rank of the input-output matrix describing the evolutionary goal is deficient. The maximal compression possible (the rank of the goal) determines the size of the narrowest part of the network—that is the bow-tie. A further requirement is that a process is active to reduce the number of links in the network, such as product-rule mutations, otherwise a non-bow-tie solution is found in the evolutionary simulations. This offers a mechanism to understand a common architectural principle of biological systems, and a way to quantitate the effective rank of the goals under which they evolved. PMID:25798588

  7. Urban Kinship Ties in South India: A Case Study

    ERIC Educational Resources Information Center

    Ramu, G. N.

    1974-01-01

    This article is a sociological analysis of the South Indian Family organization in an urban setting; in particular, it describes the nature of urban kinship ties and attempts to find differences in kinship ties across class and caste lines. (Author/HMV)

  8. 12 CFR 563.36 - Tying restriction exception.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Tying restriction exception. 563.36 Section 563.36 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS ASSOCIATIONS-OPERATIONS Operation and Structure § 563.36 Tying restriction exception. (a) Safe harbor for...

  9. 12 CFR 563.36 - Tying restriction exception.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true Tying restriction exception. 563.36 Section 563.36 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS ASSOCIATIONS-OPERATIONS Operation and Structure § 563.36 Tying restriction exception. (a) Safe harbor for...

  10. Chord Panel Post, Vertical X Bracing & Horizontal Tie Joint ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Chord Panel Post, Vertical X Bracing & Horizontal Tie Joint Detail; Chord Joining Block & Spacer Block Detail; Cross Bracing Joint Detail; Chord Panel Post Diagonal & Horizontal Tie Joint Detail - Jackson Covered Bridge, Spanning Sugar Creek, CR 775N (Changed from Spanning Sugar Creek), Bloomingdale, Parke County, IN

  11. 12 CFR 225.7 - Exceptions to tying restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Exceptions to tying restrictions. 225.7 Section... SYSTEM BANK HOLDING COMPANIES AND CHANGE IN BANK CONTROL (REGULATION Y) Regulations General Provisions...-tying restrictions of section 106 of the Bank Holding Company Act Amendments of 1970 (12 U.S.C....

  12. A simple and rapid method of repeated tie over dressing

    PubMed Central

    Singh, Hardeep; Aggarwal, Aditya; Khazanchi, Rakesh Kumar; Mahendru, Sanjay; Brajesh, Vimalendu; Singh, Sukhdeep; Krishnan, S.

    2015-01-01

    Tie overdressing is commonly used to secure the graft against the raw surface and prevent loss due to of hematoma or seroma. A conventional tie over dressing with silk sutures, is a useful method of securing the graft to raw area. Refixation is difficult when repeated tie over dressings are needed. We assessed a low cost repeated tie over dressing method using sterile sample collection containers and silk suture threads in eight patients. After the graft is applied on the bed, tie-over stitches are taken, and paraffin gauze is applied over with adequate padding; the tie over sutures are passed through the container and the lid is tightened over it to complete the dressing. The lid can be unscrewed easily at any time to inspect the graft and can be easily reapplied in the outpatient department. The skin graft take in all the patients was complete without any seroma or hematoma. A novel and low-cost tie over dressing that enables simple fixation of the dressing, to maintain proper position of grafts that require repeated fixation is reported here. PMID:25991891

  13. 77 FR 21620 - Notice of the Buy America Waiver Request for Vossloh 101-LV Concrete Ties

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ...America Waiver Request for Vossloh 101-LV Concrete Ties AGENCY: Federal Railroad Administration...for the purchase of Vossloh 101-LV concrete ties, which contain certain components...the installation of Vossloh 101-LV concrete ties. FRA has received this...

  14. 75 FR 34941 - Review of the Commission's Program Access Rules and Examination of Programming Tying Arrangements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ...Program Access Rules and Examination of Programming Tying Arrangements AGENCY: Federal...Program Access Rules and Examination of Programming Tying Arrangements, MB Docket No...Program Access Rules and Examination of Programming Tying Arrangements, MB Docket...

  15. Location Prediction in Social Media Based on Tie Strength 

    E-print Network

    McGee, Jeffrey A

    2013-04-29

    We propose a novel network-based approach for location estimation in social media that integrates evidence of the social tie strength between users for improved location estimation. Concretely, we propose a location estimator – Friendly...

  16. Surgeon's Experience Tied to Success of Thyroid Removal

    MedlinePLUS

    ... 155060.html Surgeon's Experience Tied to Success of Thyroid Removal: Study Patients should ask how many of ... Oct. 8, 2015 (HealthDay News) -- Patients who undergo thyroid removal may be less likely to suffer complications ...

  17. Older Adults' Hearing Loss May Be Tied to Earlier Death

    MedlinePLUS

    ... Adults' Hearing Loss May Be Tied to Earlier Death Findings don't prove that impaired hearing is ... loss could have directly contributed to the higher death rates seen in this study. Still, Kim pointed ...

  18. Chronic Heartburn Drugs Tied to Higher Risk of Kidney Disease

    MedlinePLUS

    ... Chronic Heartburn Drugs Tied to Higher Risk of Kidney Disease But studies weren't designed to prove ... to be linked with increased risk of chronic kidney disease, two new studies suggest. Prilosec, Nexium and ...

  19. Kidney Woes Tied to Raised Cancer Risk, Study Finds

    MedlinePLUS

    ... nlm.nih.gov/medlineplus/news/fullstory_155691.html Kidney Woes Tied to Raised Cancer Risk, Study Finds ... 12, 2015 THURSDAY, Nov. 12, 2015 (HealthDay News) -- Kidney failure and having a kidney transplant may increase ...

  20. Quality versus quantity of social ties in experimental cooperative networks.

    PubMed

    Shirado, Hirokazu; Fu, Feng; Fowler, James H; Christakis, Nicholas A

    2013-01-01

    Recent studies suggest that allowing individuals to choose their partners can help to maintain cooperation in human social networks; this behaviour can supplement behavioural reciprocity, whereby humans are influenced to cooperate by peer pressure. However, it is unknown how the rate of forming and breaking social ties affects our capacity to cooperate. Here we use a series of online experiments involving 1,529 unique participants embedded in 90 experimental networks, to show that there is a 'Goldilocks' effect of network dynamism on cooperation. When the rate of change in social ties is too low, subjects choose to have many ties, even if they attach to defectors. When the rate is too high, cooperators cannot detach from defectors as much as defectors re-attach and, hence, subjects resort to behavioural reciprocity and switch their behaviour to defection. Optimal levels of cooperation are achieved at intermediate levels of change in social ties. PMID:24226079

  1. Job Stress Tied to Stroke Risk, Study Suggests

    MedlinePLUS

    ... nih.gov/medlineplus/news/fullstory_155147.html Job Stress Tied to Stroke Risk, Study Suggests Those with ... Oct. 14, 2015 (HealthDay News) -- Having a high-stress job, particularly one that is demanding but offers ...

  2. Military Deployment Tied to Greater Odds of Child Abuse, Neglect

    MedlinePLUS

    ... html Military Deployment Tied to Greater Odds of Child Abuse, Neglect Periods during and just after deployment ... said Dr. Bob Sege, a pediatrician specializing in child abuse and vice president of Health Resources in ...

  3. Chord, Horizontal Tie Bar & Crossbracing Joint Details; Crossbracing Center ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Chord, Horizontal Tie Bar & Crossbracing Joint Details; Crossbracing Center Joint Detail; Chord, Panel Posts, Braces & Counterbrace Joint Detail - Brownsville Covered Bridge, Spanning East Fork Whitewater River (moved to Eagle Creek Park, Indianapolis), Brownsville, Union County, IN

  4. DO TIE LABORATORY BASED ASSESSMENT METHODS REALLY PREDICT FIELD EFFECTS?

    EPA Science Inventory

    Sediment Toxicity Identification and Evaluation (TIE) methods have been developed for both porewaters and whole sediments. These relatively simple laboratory methods are designed to identify specific toxicants or classes of toxicants in sediments; however, the question of whethe...

  5. DO TIE LABORATORY BASED METHODS REALLY REFLECT FIELD CONDITIONS

    EPA Science Inventory

    Sediment Toxicity Identification and Evaluation (TIE) methods have been developed for both interstitial waters and whole sediments. These relatively simple laboratory methods are designed to identify specific toxicants or classes of toxicants in sediments; however, the question ...

  6. Home Pesticide Use Tied to Child Cancer Risk

    MedlinePLUS

    ... nih.gov/medlineplus/news/fullstory_154613.html Home Pesticide Use Tied to Child Cancer Risk Indoor insecticides ... issue of Pediatrics , do not prove that chemical pesticides directly contribute to the cancers. And if they ...

  7. 18. Windlass capstan, looking aft. Windlass used for tying up ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Windlass capstan, looking aft. Windlass used for tying up as well as raising and lowering boat on starboard side. - U.S. Coast Guard Cutter BRAMBLE, Waterfront at Lincoln Avenue, Port Huron, St. Clair County, MI

  8. 9. DETAIL OF EAST PIER OF BRIDGE, SHOWING STEEL TIE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. DETAIL OF EAST PIER OF BRIDGE, SHOWING STEEL TIE BARS INSERTED TO STABILIZE CRACKS. - Pennsylvania Railroad, 52nd Street Bridge, North Fifty-second Street at Lancaster Avenue, Philadelphia, Philadelphia County, PA

  9. Flute stabilization by a cold line-tied blanket

    SciTech Connect

    Segal, D.; Wickham, M.; Rynn, N.

    1982-09-01

    The curvature-driven flute instability in an axisymmetric mirror was stabilized by an annular line-tied plasma blanket. A significant temperature difference was maintained between core and blanket. Theoretical calculations support the experimental observations.

  10. Too Much Weight in Midlife Tied to Earlier Alzheimer's

    MedlinePLUS

    Too Much Weight in Midlife Tied to Earlier Alzheimer's Slimming down might delay dementia, research suggests To ... Researchers found that among 142 elderly adults with Alzheimer's disease, those who were overweight at age 50 ...

  11. Childhood Whooping Cough Tied to Small Rise in Epilepsy Risk

    MedlinePLUS

    ... Childhood Whooping Cough Tied to Small Rise in Epilepsy Risk But chances of any one child getting ... increased risk for a young child to develop epilepsy, a new study finds. Whooping cough (pertussis) is ...

  12. The Imagery Exchange (TIE): Open Source Imagery Management System

    NASA Astrophysics Data System (ADS)

    Alarcon, C.; Huang, T.; Thompson, C. K.; Roberts, J. T.; Hall, J. R.; Cechini, M.; Schmaltz, J. E.; McGann, J. M.; Boller, R. A.; Murphy, K. J.; Bingham, A. W.

    2013-12-01

    The NASA's Global Imagery Browse Service (GIBS) is the Earth Observation System (EOS) imagery solution for delivering global, full-resolution satellite imagery in a highly responsive manner. GIBS consists of two major subsystems, OnEarth and The Imagery Exchange (TIE). TIE is the GIBS horizontally scaled imagery workflow manager component, an Open Archival Information System (OAIS) responsible for orchestrating the acquisition, preparation, generation, and archiving of imagery to be served by OnEarth. TIE is an extension of the Data Management and Archive System (DMAS), a high performance data management system developed at the Jet Propulsion Laboratory by leveraging open source tools and frameworks, which includes Groovy/Grails, Restlet, Apache ZooKeeper, Apache Solr, and other open source solutions. This presentation focuses on the application of Open Source technologies in developing a horizontally scaled data system like DMAS and TIE. As part of our commitment in contributing back to the open source community, TIE is in the process of being open sourced. This presentation will also cover our current effort in getting TIE in to the hands of the community from which we benefited from.

  13. 78 FR 75547 - Prestressed Concrete Steel Rail Tie Wire From Thailand: Preliminary Determination of Sales at Not...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ...Administration [A-549-829] Prestressed Concrete Steel Rail Tie Wire From Thailand: Preliminary...preliminarily determines that prestressed concrete steel rail tire wire (``PC tie wire...suitable for use as prestressed tendons in concrete railroad ties (``PC tie...

  14. The architecture of support: The activation of preexisting ties and formation of new ties for tailored support.

    PubMed

    Gage-Bouchard, Elizabeth A; LaValley, Susan; Panagakis, Christina; Shelton, Rachel C

    2015-06-01

    This study examines differences in the resources, information, and support parents coping with pediatric cancer accessed from different types of network contacts. Using interviews with parents of childhood cancer patients (N = 80 parents), we examine (1) if parents rely on different types of network ties to access tailored information, resources or support; (2) differences in the nature or utility of information, resources, and support offered by different types of network contacts; and (3) the role of health-related professionals in brokering new network ties. Findings show that after a child's cancer diagnosis, parents received support from a broad portfolio of network members, which included preexisting network ties to friends and families as well as the formation of new ties to other cancer families and health-related professionals. Family, friends, and neighbors offered logistical support that aided balancing preexisting work and household responsibilities with new obligations. Parents formed new ties to other families coping with cancer for tailored health-related emotional and informational support. Health-related professionals served as network brokers, who fostered the development of new network ties and connected parents with supportive resources. PMID:25888807

  15. Assessing Call and SMS Logs as an Indication of Tie Strength

    E-print Network

    their pattern of communication. When a relationship has stronger tie strength, there is generally more communication and when a relationship has weaker tie strength there is generally less communication [18 in modeling tie strength? Frequency and duration of communication has long been cited as a major aspect of tie

  16. Tie Tube Heat Transfer Modeling for Bimodal Nuclear Thermal Rockets

    SciTech Connect

    Clough, Joshua A.; Starkey, Ryan P.; Lewis, Mark J.; Lavelle, Thomas M.

    2007-01-30

    Bimodal nuclear thermal rocket systems have been shown to reduce the weight and cost of space vehicles to Mars and beyond by utilizing the reactor for power generation in the relatively long duration between burns in an interplanetary trajectory. No information, however, is available regarding engine and reactor-level operation of such bimodal systems. The purpose of this project is to generate engine and reactor models with sufficient fidelity and flexibility to accurately study the component-level effects of operating a propulsion-designed reactor at power generation levels. Previous development of a 1-D reactor and tie tube model found that ignoring heat generation inside of the tie tube leads to under-prediction of the temperature change and over-prediction of pressure change across the tie tube. This paper will present the development and results of a tie tube model that has been extended to account for heat generation, specifically in the moderator layer. This model is based on a 1-D distribution of power in the fuel elements and tie tubes, as a precursor to an eventual neutron-driven reactor model.

  17. Mechanistic modelling of the links between environment, mosquitoes and malaria transmission in the current and future climates of West Africa

    E-print Network

    Yamana, Teresa K. (Teresa Keiko)

    2015-01-01

    Malaria transmission in West Africa is closely tied to climate, as rain fed water pools provide breeding habitat for the anopheles mosquito vector, and temperature affects the mosquito's ability to spread disease. This ...

  18. Structure and tie strengths in mobile communication networks.

    PubMed

    Onnela, J-P; Saramäki, J; Hyvönen, J; Szabó, G; Lazer, D; Kaski, K; Kertész, J; Barabási, A-L

    2007-05-01

    Electronic databases, from phone to e-mails logs, currently provide detailed records of human communication patterns, offering novel avenues to map and explore the structure of social and communication networks. Here we examine the communication patterns of millions of mobile phone users, allowing us to simultaneously study the local and the global structure of a society-wide communication network. We observe a coupling between interaction strengths and the network's local structure, with the counterintuitive consequence that social networks are robust to the removal of the strong ties but fall apart after a phase transition if the weak ties are removed. We show that this coupling significantly slows the diffusion process, resulting in dynamic trapping of information in communities and find that, when it comes to information diffusion, weak and strong ties are both simultaneously ineffective. PMID:17456605

  19. What are the molecular ties that maintain genomic loops?

    PubMed

    Marenduzzo, Davide; Faro-Trindade, Inês; Cook, Peter R

    2007-03-01

    The formation of genomic loops by proteins bound at sites scattered along a chromosome has a central role in many cellular processes, such as transcription, recombination and replication. Until recently, few such loops had been analyzed in any detail, and there was little agreement about the nature of the molecular ties maintaining these loops. Recent evidence suggests that loops are found in both prokaryotes and eukaryotes, and that the transcription machinery is a molecular tie. In addition, results obtained using site-specific recombination in bacteria and chromosome conformation capture in eukaryotes support the idea that active transcription units are in close contact. These data are consistent with a model for genome organization in which active polymerases cluster into transcription 'factories', which, inevitably, loops the intervening DNA. They are also consistent with the ties functioning as barriers, silencers, enhancers or locus control regions, depending on their positions relative to other genes. PMID:17280735

  20. Time varying networks and the weakness of strong ties.

    PubMed

    Karsai, Márton; Perra, Nicola; Vespignani, Alessandro

    2014-01-01

    In most social and information systems the activity of agents generates rapidly evolving time-varying networks. The temporal variation in networks' connectivity patterns and the ongoing dynamic processes are usually coupled in ways that still challenge our mathematical or computational modelling. Here we analyse a mobile call dataset and find a simple statistical law that characterize the temporal evolution of users' egocentric networks. We encode this observation in a reinforcement process defining a time-varying network model that exhibits the emergence of strong and weak ties. We study the effect of time-varying and heterogeneous interactions on the classic rumour spreading model in both synthetic, and real-world networks. We observe that strong ties severely inhibit information diffusion by confining the spreading process among agents with recurrent communication patterns. This provides the counterintuitive evidence that strong ties may have a negative role in the spreading of information across networks. PMID:24510159

  1. Structure and tie strengths in mobile communication networks

    PubMed Central

    Onnela, J.-P.; Saramäki, J.; Hyvönen, J.; Szabó, G.; Lazer, D.; Kaski, K.; Kertész, J.; Barabási, A.-L.

    2007-01-01

    Electronic databases, from phone to e-mails logs, currently provide detailed records of human communication patterns, offering novel avenues to map and explore the structure of social and communication networks. Here we examine the communication patterns of millions of mobile phone users, allowing us to simultaneously study the local and the global structure of a society-wide communication network. We observe a coupling between interaction strengths and the network's local structure, with the counterintuitive consequence that social networks are robust to the removal of the strong ties but fall apart after a phase transition if the weak ties are removed. We show that this coupling significantly slows the diffusion process, resulting in dynamic trapping of information in communities and find that, when it comes to information diffusion, weak and strong ties are both simultaneously ineffective. PMID:17456605

  2. Role of the angiopoietin/Tie system in pregnancy (Review)

    PubMed Central

    KAPPOU, D.; SIFAKIS, S.; KONSTANTINIDOU, A.; PAPANTONIOU, N.; SPANDIDOS, D.A.

    2015-01-01

    Angiopoietin-1 and -2 are endogenous ligands for the vascular endothelium-specific receptor tyrosine kinase Tie-2. The angiopoietin/Tie system plays a critical role in the regulation of endothelial cell survival and vascular maturation and stability. Apart from its well-established role in vascular morphogenesis, emerging data support the involvement of angiopoietins in inflammation and various malignancies. Previous studies have underlined the significance of several angiogenic factors in normal placental development. In addition, angiogenic imbalance is observed in pregnancy complications related to impaired placentation, such as preeclampsia (PE) and intrauterine growth restriction (IUGR). However, there is only limited information available on the role of the angiopoietin/Tie system in the establishment of a competent feto-maternal vascular system. In this review, we present the current knowledge regarding the role of angiopoietins in normal pregnancy and pregnancy complications. PMID:25780392

  3. Automatic Tie Pointer for In-Situ Pointing Correction

    NASA Technical Reports Server (NTRS)

    Deen, Robert G/

    2011-01-01

    The MARSAUTOTIE program generates tie points for use with the Mars pointing correction software "In-Situ Pointing Correction and Rover Microlocalization," (NPO-46696) Soft ware Tech Briefs, Vol. 34, No. 9 (September 2010), page 18, in a completely automated manner, with no operator intervention. It takes the place of MARSTIE, although MARSTIE can be used to interactively edit the tie points afterwards. These tie points are used to create a mosaic whose seams (boundaries of input images) have been geometrically corrected to reduce or eliminate errors and mis-registrations. The methods used to find appropriate tie points for use in creating a mosaic are unique, having been designed to work in concert with the "MARSNAV" program to be most effective in reducing or eliminating geometric seams in a mosaic. The program takes the input images and finds overlaps according to the nominal pointing. It then finds the most interesting areas using a scene activity metric. Points with higher scene activity are more likely to correlate successfully in the next step. It then uses correlation techniques to find matching points in the overlapped image. Finally, it performs a series of steps to reduce the number of tie points to a manageable level. These steps incorporate a number of heuristics that have been devised using experience gathered by tie pointing mosaics manually during MER operations. The software makes use of the PIG library as described in "Planetary Image Geometry Library" (NPO-46658), NASA Tech Briefs, Vol. 34, No. 12 (December 2010), page 30, so it is multi-mission, applicable without change to any in-situ mission supported by PIG. The MARSAUTOTIE algorithm is automated, so it requires no user intervention. Although at the time of this reporting it has not been done, this program should be suitable for integration into a fully automated mosaic production pipeline.

  4. Social ties and health: A social neuroscience perspective

    PubMed Central

    Eisenberger, Naomi I.

    2013-01-01

    Research over the last several decades has shown that the health of the body is intimately tied to the strength of our social connections, but why? This article reviews evidence from affective and social neuroscience suggesting that, because of the importance of social ties for mammalian survival, threats to social connection are processed by some of the same neural regions that process basic threats to survival and consequently trigger physiological threat responses that have negative health implications. Likewise, social support is processed by some of the same neural regions that process safety or protection from basic threats and inhibit these same health-relevant physiological threat responses. PMID:23395461

  5. Welded tie plate feasibility study for ITER central solenoid structure

    NASA Astrophysics Data System (ADS)

    Walsh, R.; McRae, D.; Dalder, E.; Litherland, S.; Goddard, R.; Han, K.; Trosen, M.; Kuhlmann, D. D.

    2014-01-01

    The result of a Nitronic 50 (N50) weld-screening program conducted in support of CS-Tie Plate Structure Design and Development is reported here. The goal of this program is to evaluate four different weld practices and to select the best weld practice for thick section welding of the N50 tie plate structure. The structure design specifies both the weld and base metals have the same minimum mechanical properties requirements. The criteria for selecting the best weld practice are based on the combination of the 295 K tensile properties and the 4 K-tensile, fatigue, and fracture-toughness properties.

  6. Terahertz heterodyne imaging with InGaAs-based bow-tie diodes

    NASA Astrophysics Data System (ADS)

    Minkevi?ius, Linas; Tamošiunas, Vincas; Kašalynas, Irmantas; Seliuta, Dalius; Valušis, Gintaras; Lisauskas, Alvydas; Boppel, Sebastian; Roskos, Hartmut G.; Köhler, Klaus

    2011-09-01

    Room-temperature detection and imaging in transmission and reflection geometries at 0.591 THz with planar asymmetrically shaped InGaAs diodes (also called bow-tie diodes) are demonstrated in direct and heterodyne mode. The sensitivity of the diodes is found to be 6 V/W in direct mode, and the noise-equivalent power (NEP) in direct and heterodyne mode is estimated to be about 4 nW/?H z and 230 fW/Hz for a local-oscillator power of 11 ?W, respectively. The improvement of the dynamic range by heterodyning over direct power detection amounts to about 20 dB using pixel read-out times relevant to real-time imaging conditions.

  7. The Strength of the Strongest Ties in Collaborative Problem Solving

    NASA Astrophysics Data System (ADS)

    de Montjoye, Yves-Alexandre; Stopczynski, Arkadiusz; Shmueli, Erez; Pentland, Alex; Lehmann, Sune

    2014-06-01

    Complex problem solving in science, engineering, and business has become a highly collaborative endeavor. Teams of scientists or engineers collaborate on projects using their social networks to gather new ideas and feedback. Here we bridge the literature on team performance and information networks by studying teams' problem solving abilities as a function of both their within-team networks and their members' extended networks. We show that, while an assigned team's performance is strongly correlated with its networks of expressive and instrumental ties, only the strongest ties in both networks have an effect on performance. Both networks of strong ties explain more of the variance than other factors, such as measured or self-evaluated technical competencies, or the personalities of the team members. In fact, the inclusion of the network of strong ties renders these factors non-significant in the statistical analysis. Our results have consequences for the organization of teams of scientists, engineers, and other knowledge workers tackling today's most complex problems.

  8. 4. Photocopy of photograph, JANE MOSELEY (VESSEL 53) TIED UP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopy of photograph, JANE MOSELEY (VESSEL 53) TIED UP AT DOCK IN UNKNOWN LOCATION. Date and photographer unknown. (Original in Mariners Museum, Newport News, Virginia, negative #625) - Shooters Island, Ships Graveyard, Vessel No. 53, Newark Bay, Staten Island (subdivision), Richmond County, NY

  9. EELE408 Photovoltaics Lecture 22: Grid Tied Systems

    E-print Network

    Kaiser, Todd J.

    @ece.montana.edu Department of Electrical and Computer Engineering Montana State University - Bozeman Grid Tied System anchors Installed Anchor System Fl hi dd d h f i hi l d 4 Flashing added as the roof is shingled Solar 14 Inverter Electrical Panel Monitoring Exterior Labeled PV Disconnect Required 15 Inverter 16

  10. International Project Management TIES Observation Session at UA

    E-print Network

    International Project Management Office TIES Observation Session at UA May 4th 2010 Roberto Escarré Director, International Project Management Office, University of Alicante, Spain #12;- About the OGPI staff members, in 4 different areas: - Financial and administrative - IT - Project management - Legal

  11. People Interview: Black-tie science gets modern

    NASA Astrophysics Data System (ADS)

    2009-03-01

    INTERVIEW Black-tie science gets modern Baroness Susan Greenfield CBE is director of the Royal Institution and professor of pharmacology at Oxford where she heads a multidisciplinary group studying neurodegenerative disorders. David Smith speaks to her about specialities, keeping busy and how science is changing.

  12. The Strength of the Strongest Ties in Collaborative Problem Solving

    PubMed Central

    de Montjoye, Yves-Alexandre; Stopczynski, Arkadiusz; Shmueli, Erez; Pentland, Alex; Lehmann, Sune

    2014-01-01

    Complex problem solving in science, engineering, and business has become a highly collaborative endeavor. Teams of scientists or engineers collaborate on projects using their social networks to gather new ideas and feedback. Here we bridge the literature on team performance and information networks by studying teams' problem solving abilities as a function of both their within-team networks and their members' extended networks. We show that, while an assigned team's performance is strongly correlated with its networks of expressive and instrumental ties, only the strongest ties in both networks have an effect on performance. Both networks of strong ties explain more of the variance than other factors, such as measured or self-evaluated technical competencies, or the personalities of the team members. In fact, the inclusion of the network of strong ties renders these factors non-significant in the statistical analysis. Our results have consequences for the organization of teams of scientists, engineers, and other knowledge workers tackling today's most complex problems. PMID:24946798

  13. Preventing Cauliflower Ear with a Modified Tie-Through Technique.

    ERIC Educational Resources Information Center

    Dimeff, Robert J.; Hough, David O.

    1989-01-01

    Describes a quick, simple tie-through suture technique (in which a collodion packing is secured to the auricle with two buttons) for preventing cauliflower ear following external ear trauma in wrestlers and boxers. The technique ensures constant compression; multiple treatments for fluid reaccumulation are rarely necessary. (SM)

  14. Teaching Tongue-Tied Students: Ankyloglossia in the Instrumental Classroom

    ERIC Educational Resources Information Center

    Dovel, Jason

    2010-01-01

    Ankyloglossia is a significant medical condition that has not been adequately addressed in music education literature. While practically every instructor will have students who struggle with ankyloglossia, many teachers are entirely unaware of this condition's various symptoms and treatments. Ankyloglossia, more commonly known as tongue-tie, is a…

  15. 26. ROOM 210, VIEW TO THE SOUTHEAST. EXPOSED TIE BEAMS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. ROOM 210, VIEW TO THE SOUTHEAST. EXPOSED TIE BEAMS AT CEILING ARE BOXED IN PLYWOOD. WAINSCOTING IS PLYWOOD PANELING. CEILING AND UPPER WALL TREATMENT IS GYPSUM BOARD. CLERESTORY WINDOWS LINE BOTH LONG SIDES OF ROOM. - Presidio of San Francisco, Cavalry Stables, Cowles Street, between Lincoln Boulevard & McDowell Street, San Francisco, San Francisco County, CA

  16. Maintaining Family Ties: Inclusive Practice in Foster Care.

    ERIC Educational Resources Information Center

    Palmer, Sally E.

    Loss and uprootedness are core problems of enforced separation, and are especially hard on children. Children in out-of-home care need help in dealing with separation, particularly in maintaining ties with family. This report details a study of how 36 social workers in 2 Canadian child protection agencies have managed separation issues with the…

  17. Automatic transmission

    SciTech Connect

    Miura, M.; Aoki, H.

    1988-02-02

    An automatic transmission is described comprising: an automatic transmission mechanism portion comprising a single planetary gear unit and a dual planetary gear unit; carriers of both of the planetary gear units that are integral with one another; an input means for inputting torque to the automatic transmission mechanism, clutches for operatively connecting predetermined ones of planetary gear elements of both of the planetary gear units to the input means and braking means for restricting the rotation of predetermined ones of planetary gear elements of both of the planetary gear units. The clutches are disposed adjacent one another at an end portion of the transmission for defining a clutch portion of the transmission; a first clutch portion which is attachable to the automatic transmission mechanism portion for comprising the clutch portion when attached thereto; a second clutch portion that is attachable to the automatic transmission mechanism portion in place of the first clutch portion for comprising the clutch portion when so attached. The first clutch portion comprising first clutch for operatively connecting the input means to a ring gear of the single planetary gear unit and a second clutch for operatively connecting the input means to a single gear of the automatic transmission mechanism portion. The second clutch portion comprising a the first clutch, the second clutch, and a third clutch for operatively connecting the input member to a ring gear of the dual planetary gear unit.

  18. AQUIFER TRANSMISSIVITY

    EPA Science Inventory

    Evaluation of groundwater resources requires the knowledge of the capacity of aquifers to store and transmit ground water. This requires estimates of key hydraulic parameters, such as the transmissivity, among others. The transmissivity T (m2/sec) is a hydrauli...

  19. 78 FR 25303 - Prestressed Concrete Steel Rail Tie Wire From China, Mexico, and Thailand

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ...Nos. 731-TA-1207-1209 (Preliminary)] Prestressed Concrete Steel Rail Tie Wire From China, Mexico, and Thailand Institution...materially retarded, by reason of imports from prestressed concrete steel rail tie wire from China, Mexico, and Thailand,...

  20. Linkage of genomic biomarkers to whole organism endpoints in a Toxicity Identification Evaluation (TIE).

    EPA Science Inventory

    Aquatic organisms are exposed to many toxic chemicals and interpreting the cause and effect relationships between occurrence and impairment is difficult. Toxicity Identification Evaluation (TIE) provides a systematic approach for identifying responsible toxicants. TIE relies on ...

  1. Shingles Transmission

    MedlinePLUS

    ... Search The CDC Cancel Submit Search The CDC Shingles (Herpes Zoster) Note: Javascript is disabled or is not supported ... message, please visit this page: About CDC.gov . Shingles Home About Shingles Overview Signs & Symptoms Transmission Complications ...

  2. Bipartite Network Model for Inferring Hidden Ties in Crime Data

    E-print Network

    Isah, Haruna; Trundle, Paul

    2015-01-01

    Certain crimes are hardly committed by individuals but carefully organised by group of associates and affiliates loosely connected to each other with a single or small group of individuals coordinating the overall actions. A common starting point in understanding the structural organisation of criminal groups is to identify the criminals and their associates. Situations arise in many criminal datasets where there is no direct connection among the criminals. In this paper, we investigate ties and community structure in crime data in order to understand the operations of both traditional and cyber criminals, as well as to predict the existence of organised criminal networks. Our contributions are twofold: we propose a bipartite network model for inferring hidden ties between actors who initiated an illegal interaction and objects affected by the interaction, we then validate the method in two case studies on pharmaceutical crime and underground forum data using standard network algorithms for structural and com...

  3. Ties that Blind: Perpetuation of Racial Comfort and Discomfort at a Community College

    ERIC Educational Resources Information Center

    Price, Douglas B.; Hyle, Adrienne E.; Jordan, Kitty V.

    2009-01-01

    Interviews with 17 African American students and 19 White students were employed to examine interracial relations at a predominantly White community college campus. Seen through the lens of Granovetter's strength of ties theory, the interview findings revealed that strong intraracial ties and the absence of weak interracial ties inhibited…

  4. Estimation of the Force on the Syringe Tie-rods from Fringing

    E-print Network

    McDonald, Kirk

    SS304L or SS316L. · However Stainless Steel 17-4 PH was used. ­ This stainless steel is martensiticEstimation of the Force on the Syringe Tie-rods from Fringing Magnetic Fields Steve Kahn 5 April 2006 #12;Tie-rod location #12;#12;Tie-rod Specifications Indicate that They Should Be Non-Magnetic · 1

  5. 78 FR 37236 - Prestressed Concrete Steel Rail Tie Wire From China, Mexico, and Thailand

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ...731-TA-1207-1209 (Preliminary)] Prestressed Concrete Steel Rail Tie Wire From China, Mexico...Mexico, and Thailand of prestressed concrete steel rail tie wire, provided for in...reason of LTFV imports of prestressed concrete steel rail tie wire from China,...

  6. ON THE USE OF TIED-MIXTURE DISTRIBUTIONS Owen Kimball, Mari Ostendorf

    E-print Network

    ON THE USE OF TIED-MIXTURE DISTRIBUTIONS Owen Kimball, Mari Ostendorf Electrical, Computer and Systems Engineering Boston University, Boston, MA 02215 ABSTRACT Tied-mixture (or semi available for tied mixture modeling, intro- ducing algorithms for reducing training time, and provid- ing

  7. Stepfamily Formation: Implications for Adolescent Ties to Mothers, Nonresident Fathers, and Stepfathers

    ERIC Educational Resources Information Center

    King, Valarie

    2009-01-01

    This study examines how the entrance of a stepfather influences adolescent ties to mothers and nonresident fathers and how prior ties to each biological parent influence the development of stepfather-stepchild ties. Data come from 1,753 adolescents in the National Longitudinal Study of Adolescent Health who lived with a single mother in Wave 1 who…

  8. 46 CFR 112.05-3 - Main-emergency bus-tie.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...2010-10-01 2010-10-01 false Main-emergency bus-tie. 112.05-3 Section 112.05-3 Shipping...SYSTEMS General § 112.05-3 Main-emergency bus-tie. Each bus-tie between a main switchboard and an emergency...

  9. Breaking Ties with Secondary Fitness in a Genetic Algorithm for the Bin Packing Problem

    E-print Network

    Julstrom, Bryant A.

    Breaking Ties with Secondary Fitness in a Genetic Algorithm for the Bin Packing Problem Justin 56301 USA julstrom@stcloudstate.edu ABSTRACT In a genetic algorithm with integer fitnesses, ties such ties to the algorithm's advantage. Such a secondary fitness for the Bin Packing Problem is based

  10. Bloch lines, cross ties, and taffy in permalloy (invited)

    NASA Astrophysics Data System (ADS)

    Herman, D. A., Jr.; Argyle, B. E.; Petek, B.

    1987-04-01

    Cross ties and their attendant Bloch lines have been imaged optically for the first time in permalloy films. Kerr effect images, recorded with our laser magneto-optic microscope (LAMOM), on 50-?m square films (300, 800, and 5800 Å thick), are consistent with wall types seen in large sheet films by other methods. In the 300- and 800-Å samples 180° domain walls are cross-tie type; ties do not occur in the 5800-Å sample. We observe several effects of film-edge proximity on the 180° walls not previously reported. In the thinner films, the density of ties (and Bloch lines) increases as a wall is driven closer to an edge. Magnetization sectoring occurs about the edge side of a wall when it is forced sufficiently close. For all three thicknesses, the 180° walls bow toward the nearest edge, the bow increasing with proximity. The 180° walls arise from the lowest-energy demagnetized state (Kittel configuration for a square) by applying a bias field which displaces the cluster knot formed by two intersecting 90° walls on the square's diagonals. At a threshold on the order of 10 Oe, the cluster splits, forming two triplet knots connected by the 180° wall. Following bifurcation, all walls bisect the angles between adjacent domain magnetizations. This indicates that the energies of formation for the 180° wall and the extra knot stem from magnetic charge accumulated near the walls and film edges prior to the transformation. Knot displacement and bifurcation can be reversed provided no wall makes contact with an edge. Edge contact (followed by bias reduction) nucleates complex domain structures which are not simply returned to the Kittel state. When the drive is cycled, the process is reminiscent of pulling taffy.

  11. Suicide: the key role of short range ties

    E-print Network

    Röhner, B M

    2005-01-01

    The paper explores the connection between short-range social ties (i.e. links with close relatives) and the occurrence of suicide. The objective is to discriminate between a model based on social ties and a model based on psychological traumas. Our methodological strategy is to focus on instances characterized by the severance of some social ties. We consider several situations of this kind. (i) Prisoners in the first days after their incarceration. (ii) Prisoners in solitary confinement. (iii) Prisoners who are transferred from one prison to another. (iv) Prisoners in closed versus open prisons. (v) Prisoners in the weeks following their release. (vi) Immigrants in the years following their relocation. (vii) Unmarried versus married people. Furthermore, in order to test the impact of major shocks we consider the responses in terms of suicides to the following shocks. (i) The attack of September 11, 2001 in Manhattan. (ii) The Korean War. (iii) The two world wars. (iv) The Great Depression in the United State...

  12. Laptop image transmission equipment

    NASA Astrophysics Data System (ADS)

    Mocenter, Michael M.

    1991-12-01

    Imagery and other visual information have become a critical element in planning and performing modern military operations. The effectiveness of this imagery information is often directly tied to the time it takes to get from the collector of this imagery to the user of the imagery. Hard copy distribution of annotated imagery to the tactical commander is hampered by the lack of effective communications paths, and the tactical use of hand held imagery is restricted by the lack of film processing facilities. The military has begun to rely on electronic imagery and digital communications technology for answers, with some success. The new obstacles created by applied electronic imagery are interoperability standards and effective use of communications bandwidth in a tactical environment. New technological developments in computer hardware/software have changed this situation by allowing for the gathering, dissemination, and transfer of near-real-time information to various intelligence audiences at any location. The Naval Air Development Center (NAVAIRDEVCEN) has coupled commercial-off-the-shelf (COTS) technology with National Image Transmission Formats (NITF) Standards to develop a Secondary Imagery Dissemination System (SIDS) package that is designed to meet the flexibility challenge of the tactical military environment. This tailorable SIDS package is called Laptop Image Transmission Equipment (LITE). The LITE system is an extension of the Navy's existing Fleet Imagery Support Terminal (FIST) into the man-portable tactical environment. As such, LITE development is focused on developing flexible imagery input (from sources such as filmless cameras) and connectivity to tactical communications paths and ruggedization/miniaturization issues. The LITE system, in prototype form, has already found application through operational use in special operations, counter narcotics operations, and classic air/ground/sea military operations. This paper provides an overview of the LITE components, specifications, operations, and future developments for the system.

  13. Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE)

    PubMed Central

    Paull, Evan O.; Carlin, Daniel E.; Niepel, Mario; Sorger, Peter K.; Haussler, David; Stuart, Joshua M.

    2013-01-01

    Motivation: Identifying the cellular wiring that connects genomic perturbations to transcriptional changes in cancer is essential to gain a mechanistic understanding of disease initiation, progression and ultimately to predict drug response. We have developed a method called Tied Diffusion Through Interacting Events (TieDIE) that uses a network diffusion approach to connect genomic perturbations to gene expression changes characteristic of cancer subtypes. The method computes a subnetwork of protein–protein interactions, predicted transcription factor-to-target connections and curated interactions from literature that connects genomic and transcriptomic perturbations. Results: Application of TieDIE to The Cancer Genome Atlas and a breast cancer cell line dataset identified key signaling pathways, with examples impinging on MYC activity. Interlinking genes are predicted to correspond to essential components of cancer signaling and may provide a mechanistic explanation of tumor character and suggest subtype-specific drug targets. Availability: Software is available from the Stuart lab’s wiki: https://sysbiowiki.soe.ucsc.edu/tiedie. Contact: jstuart@ucsc.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:23986566

  14. TIES for Dummies 3rd Edition (Technology Identification, Evaluation, and Selection) Basic how to's to implement the TIES method

    NASA Technical Reports Server (NTRS)

    Kirby, Michelle R.

    2002-01-01

    The TIES method is a forecasting environment whereby the decision-maker has the ability to easily assess and trade-off the impact of various technologies without sophisticated and time-consuming mathematical formulations. TIES provides a methodical approach where technically feasible alternatives can be identified with accuracy and speed to reduce design cycle time, and subsequently, life cycle costs, and was achieved through the use of various probabilistic methods, such as Response Surface Methodology and Monte Carlo Simulations. Furthermore, structured and systematic techniques are utilized from other fields to identify possible concepts and evaluation criteria by which comparisons can be made. This objective is achieved by employing the use of Morphological Matrices and Multi-Attribute Decision Making techniques. Through the execution of each step, a family of design alternatives for a given set of customer requirements can be identified and assessed subjectively or objectively. This methodology allows for more information (knowledge) to be brought into the earlier phases of the design process and will have direct implications on the affordability of the system. The increased knowledge allows for optimum allocation of company resources and quantitative justification for program decisions. Finally, the TIES method provided novel results and quantitative justification to facilitate decision making in the early stages of design so as to produce affordable and quality products.

  15. Prion transmission

    PubMed Central

    Maddison, Ben C

    2010-01-01

    Prion diseases range from being highly infectious, for example scrapie and CWD, which show facile transmission between susceptible individuals, to showing negligible horizontal transmission, such as BSE and CJD, which are spread via food or iatrogenically, respectively. Scrapie and CWD display considerable in vivo dissemination, with PrPSc and infectivity being found in a range of peripheral tissues. This in vivo dissemination appears to facilitate the recently reported excretion of prion through multiple routes such as from skin, feces, urine, milk, nasal secretions, saliva and placenta. Furthermore, excreted scrapie and CWD agent is detected within environmental samples such as water and on the surfaces of inanimate objects. The cycle of “uptake of prion from the environment—widespread in vivo prion dissemination—prion excretion—prion persistence in the environment” is likely to explain the facile transmission and maintenance of these diseases within wild and farmed populations over many years. PMID:20948292

  16. Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects.

    PubMed

    Boscolo, Elisa; Limaye, Nisha; Huang, Lan; Kang, Kyu-Tae; Soblet, Julie; Uebelhoer, Melanie; Mendola, Antonella; Natynki, Marjut; Seront, Emmanuel; Dupont, Sophie; Hammer, Jennifer; Legrand, Catherine; Brugnara, Carlo; Eklund, Lauri; Vikkula, Miikka; Bischoff, Joyce; Boon, Laurence M

    2015-09-01

    Venous malformations (VMs) are composed of ectatic veins with scarce smooth muscle cell coverage. Activating mutations in the endothelial cell tyrosine kinase receptor TIE2 are a common cause of these lesions. VMs cause deformity, pain, and local intravascular coagulopathy, and they expand with time. Targeted pharmacological therapies are not available for this condition. Here, we generated a model of VMs by injecting HUVECs expressing the most frequent VM-causing TIE2 mutation, TIE2-L914F, into immune-deficient mice. TIE2-L914F-expressing HUVECs formed VMs with ectatic blood-filled channels that enlarged over time. We tested both rapamycin and a TIE2 tyrosine kinase inhibitor (TIE2-TKI) for their effects on murine VM expansion and for their ability to inhibit mutant TIE2 signaling. Rapamycin prevented VM growth, while TIE2-TKI had no effect. In cultured TIE2-L914F-expressing HUVECs, rapamycin effectively reduced mutant TIE2-induced AKT signaling and, though TIE2-TKI did target the WT receptor, it only weakly suppressed mutant-induced AKT signaling. In a prospective clinical pilot study, we analyzed the effects of rapamycin in 6 patients with difficult-to-treat venous anomalies. Rapamycin reduced pain, bleeding, lesion size, functional and esthetic impairment, and intravascular coagulopathy. This study provides a VM model that allows evaluation of potential therapeutic strategies and demonstrates that rapamycin provides clinical improvement in patients with venous malformation. PMID:26258417

  17. Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects

    PubMed Central

    Boscolo, Elisa; Limaye, Nisha; Huang, Lan; Kang, Kyu-Tae; Soblet, Julie; Uebelhoer, Melanie; Mendola, Antonella; Natynki, Marjut; Seront, Emmanuel; Dupont, Sophie; Hammer, Jennifer; Legrand, Catherine; Brugnara, Carlo; Eklund, Lauri; Vikkula, Miikka; Bischoff, Joyce; Boon, Laurence M.

    2015-01-01

    Venous malformations (VMs) are composed of ectatic veins with scarce smooth muscle cell coverage. Activating mutations in the endothelial cell tyrosine kinase receptor TIE2 are a common cause of these lesions. VMs cause deformity, pain, and local intravascular coagulopathy, and they expand with time. Targeted pharmacological therapies are not available for this condition. Here, we generated a model of VMs by injecting HUVECs expressing the most frequent VM-causing TIE2 mutation, TIE2-L914F, into immune-deficient mice. TIE2-L914F–expressing HUVECs formed VMs with ectatic blood-filled channels that enlarged over time. We tested both rapamycin and a TIE2 tyrosine kinase inhibitor (TIE2-TKI) for their effects on murine VM expansion and for their ability to inhibit mutant TIE2 signaling. Rapamycin prevented VM growth, while TIE2-TKI had no effect. In cultured TIE2-L914F–expressing HUVECs, rapamycin effectively reduced mutant TIE2-induced AKT signaling and, though TIE2-TKI did target the WT receptor, it only weakly suppressed mutant-induced AKT signaling. In a prospective clinical pilot study, we analyzed the effects of rapamycin in 6 patients with difficult–to-treat venous anomalies. Rapamycin reduced pain, bleeding, lesion size, functional and esthetic impairment, and intravascular coagulopathy. This study provides a VM model that allows evaluation of potential therapeutic strategies and demonstrates that rapamycin provides clinical improvement in patients with venous malformation. PMID:26258417

  18. [Spiritual ties of the Military Medical (Medical and Surgical) Academy].

    PubMed

    Gordienko, A V; Shamre?, V K

    2015-01-01

    Before the revolution in its educational, research and clinical potential of Military Medicine (medical and surgical) Academy was on the head position among European institutions. Not less outstanding position among all secular institutions Russian Academy held by the number and wealth of churches, chapels and baptisteries. In the temples of the academy was concentrated a significant number of miracle-working icons and of the particles holy relics, there served some of faith and piety devotees and some of them were canonized. The article presents a brief historical overview of the major Academy shrines--spiritual ties of the different generations. PMID:25916040

  19. Dynamical strength of social ties in information spreading

    NASA Astrophysics Data System (ADS)

    Miritello, Giovanna; Moro, Esteban; Lara, Rubén

    2011-04-01

    We investigate the temporal patterns of human communication and its influence on the spreading of information in social networks. The analysis of mobile phone calls of 20 million people in one country shows that human communication is bursty and happens in group conversations. These features have the opposite effects on the reach of the information: while bursts hinder propagation at large scales, conversations favor local rapid cascades. To explain these phenomena we define the dynamical strength of social ties, a quantity that encompasses both the topological and the temporal patterns of human communication.

  20. Dynamical strength of social ties in information spreading.

    PubMed

    Miritello, Giovanna; Moro, Esteban; Lara, Rubén

    2011-04-01

    We investigate the temporal patterns of human communication and its influence on the spreading of information in social networks. The analysis of mobile phone calls of 20 million people in one country shows that human communication is bursty and happens in group conversations. These features have the opposite effects on the reach of the information: while bursts hinder propagation at large scales, conversations favor local rapid cascades. To explain these phenomena we define the dynamical strength of social ties, a quantity that encompasses both the topological and the temporal patterns of human communication. PMID:21599228

  1. Review of two 1998 Mathematical Appendices Primary to Continuum Theory: Deflection Scattering and Redshift by a Particle-tied Aether

    NASA Astrophysics Data System (ADS)

    Osmaston, Miles F.

    My development of Continuum Theory rests importantly on two mathematical treatments and calculations which I wrote in 1994 and were published in 1998 as Appendices A and B to my PIRT V paper presented in London in 1996. In view of their continuing scientific relevance, this contribution to the V9 conference proceedings is a republication of those Appendices, subject to minimal re-editing. Appendix B, presented first, tackles our 1959 finding that the daylight sky brightness distribution at high altitude shows the presence of an additional contribution whose intensity and distribution which, on careful analysis, I identified as having come from a deflection scattering mechanism due to transmission by an (atmospheric) `particle-tied aether'. Appendix A shows that redshift is one of the consequences of such transmission. The parameters involved are then used to analyse the 1968 radio ground-wave caesium clock redshift observations of Sadeh et al and to extrapolate them to the intergalactic transmission paths pertinent to the cosmic redshift as a transmission effect, not a velocity. It finds this to be a reasonable evaluation within observational uncertainties, notably those of density and degree of ionization. In that case, there being no Big Bang, the temperature is precisely known from the CMBR, identified as synchrotron-type radiation from the randomly moving aether along the path, but slightly elevated where the path has traversed a heat-generating cluster.

  2. Vulnerability to changes in malaria transmission due to climate change in West Africa

    NASA Astrophysics Data System (ADS)

    Yamana, T. K.; Eltahir, E. A.

    2012-12-01

    Malaria transmission in West Africa is strongly tied to climate; temperature affects the development rate of the malaria parasite, as well as the survival of the mosquitoes that transmit the disease, and rainfall is tied to mosquito abundance, as the vector lays its eggs in rain-fed water pools. As a result, the environmental suitability for malaria transmission in this region is expected to change as temperatures rise and rainfall patterns are altered. The vulnerability to changes in transmission varies throughout West Africa. Areas where malaria prevalence is already very high will be less sensitive to changes in transmission. Increases in environmental suitability for malaria transmission in the most arid regions may still be insufficient to allow sustained transmission. However, areas were malaria transmission currently occurs at low levels are expected to be the most sensitive to changes in environmental suitability for transmission. Here, we use data on current environment and malaria transmission rates to highlight areas in West Africa that we expect to be most vulnerable to an increase in malaria under certain climate conditions. We then analyze climate predictions from global climate models in vulnerable areas, and make predictions for the expected change in environmental suitability for malaria transmission using the Hydrology, Entomology and Malaria Transmission Simulator (HYDREMATS), a mechanistic model developed to simulate village-scale response of malaria transmission to environmental variables in West Africa.

  3. 78 FR 29325 - Prestressed Concrete Steel Rail Tie Wire From Mexico, the People's Republic of China, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ...A-570-990, A-549-829] Prestressed Concrete Steel Rail Tie Wire From Mexico, the...petitions concerning imports of prestressed concrete steel rail tie wire (``PC tie wire...Antidumping Duty Petitions on Prestressed Concrete Steel Rail Tie Wire from the PRC,...

  4. 78 FR 75547 - Prestressed Concrete Steel Rail Tie Wire From Thailand: Preliminary Determination of Sales at Not...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ... International Trade Administration Prestressed Concrete Steel Rail Tie Wire From Thailand: Preliminary... concrete steel rail tire wire (``PC tie wire'') from Thailand is not being, or likely to be, sold in the... prestressed tendons in concrete railroad ties (``PC tie wire''). High carbon steel is defined as steel...

  5. Sample size calculation for the Wilcoxon-Mann-Whitney test adjusting for ties.

    PubMed

    Zhao, Yan D; Rahardja, Dewi; Qu, Yongming

    2008-02-10

    In this paper we study sample size calculation methods for the asymptotic Wilcoxon-Mann-Whitney test for data with or without ties. The existing methods are applicable either to data with ties or to data without ties but not to both cases. While the existing methods developed for data without ties perform well, the methods developed for data with ties have limitations in that they are either applicable to proportional odds alternatives or have computational difficulties. We propose a new method which has a closed-form formula and therefore is very easy to calculate. In addition, the new method can be applied to both data with or without ties. Simulations have demonstrated that the new sample size formula performs very well as the corresponding actual powers are close to the nominal powers. PMID:17487941

  6. A determination of the radio-planetary frame tie from comparison of Earth orientation parameters

    NASA Technical Reports Server (NTRS)

    Finger, M. H.; Folkner, W. M.

    1992-01-01

    The orientation of the reference frame of radio source catalogs relative to that of planetary ephemerides, or 'frame tie,' can be a major systematic error source for interplanetary spacecraft orbit determination. This work presents a method of determining the radio-planetary frame tie from a comparison of very long baseline interferometry (VLBI) and lunar laser ranging (LLR) station coordinate and earth orientation parameter estimates. A frame tie result is presented with an accuracy of 25 nrad.

  7. A determination of the radio-planetary frame tie from comparison of Earth orientation parameters

    NASA Technical Reports Server (NTRS)

    Finger, Mark Harold; Folkner, William M.

    1992-01-01

    The orientation of the reference frame of radio source catalogs relative to that of planetary ephemerides, or 'frame tie,' can be a major systematic error source for interplanetary spacecraft orbit determination. This work presents a method of determining the radio-planetary frame tie from a comparison of very long baseline interferometry (VLBI) and lunar laser ranging (LLR) station coordinate and Earth orientation parameter estimates. A frame tie result is presented with an accuracy of 25 nrad.

  8. Temperature Profile in Fuel and Tie-Tubes for Nuclear Thermal Propulsion Systems

    SciTech Connect

    Vishal Patel

    2015-02-01

    A finite element method to calculate temperature profiles in heterogeneous geometries of tie-tube moderated LEU nuclear thermal propulsion systems and HEU designs with tie-tubes is developed and implemented in MATLAB. This new method is compared to previous methods to demonstrate shortcomings in those methods. Typical methods to analyze peak fuel centerline temperature in hexagonal geometries rely on spatial homogenization to derive an analytical expression. These methods are not applicable to cores with tie-tube elements because conduction to tie-tubes cannot be accurately modeled with the homogenized models. The fuel centerline temperature directly impacts safety and performance so it must be predicted carefully. The temperature profile in tie-tubes is also important when high temperatures are expected in the fuel because conduction to the tie-tubes may cause melting in tie-tubes, which may set maximum allowable performance. Estimations of maximum tie-tube temperature can be found from equivalent tube methods, however this method tends to be approximate and overly conservative. A finite element model of heat conduction on a unit cell can model spatial dependence and non-linear conductivity for fuel and tie-tube systems allowing for higher design fidelity of Nuclear Thermal Propulsion.

  9. Automatic transmission

    SciTech Connect

    Ohkubo, M.

    1988-02-16

    An automatic transmission is described combining a stator reversing type torque converter and speed changer having first and second sun gears comprising: (a) a planetary gear train composed of first and second planetary gears sharing one planetary carrier in common; (b) a clutch and requisite brakes to control the planetary gear train; and (c) a speed-increasing or speed-decreasing mechanism is installed both in between a turbine shaft coupled to a turbine of the stator reversing type torque converter and the first sun gear of the speed changer, and in between a stator shaft coupled to a reversing stator and the second sun gear of the speed changer.

  10. Automatic transmission

    SciTech Connect

    Miki, N.

    1988-10-11

    This patent describes an automatic transmission including a fluid torque converter, a first gear unit having three forward-speed gears and a single reverse gear, a second gear unit having a low-speed gear and a high-speed gear, and a hydraulic control system, the hydraulic control system comprising: a source of pressurized fluid; a first shift valve for controlling the shifting between the first-speed gear and the second-speed gear of the first gear unit; a second shift valve for controlling the shifting between the second-speed gear and the third-speed gear of the first gear unit; a third shift valve equipped with a spool having two positions for controlling the shifting between the low-speed gear and the high-speed gear of the second gear unit; a manual selector valve having a plurality of shift positions for distributing the pressurized fluid supply from the source of pressurized fluid to the first, second and third shift valves respectively; first, second and third solenoid valves corresponding to the first, second and third shift valves, respectively for independently controlling the operation of the respective shift valves, thereby establishing a six forward-speed automatic transmission by combining the low-speed gear and the high-speed gear of the second gear unit with each of the first-speed gear, the second speed gear and the third-speed gear of the first gear unit; and means to fixedly position the spool of the third shift valve at one of the two positions by supplying the pressurized fluid to the third shift valve when the manual selector valve is shifted to a particular shift position, thereby locking the second gear unit in one of low-speed gear and the high-speed gear, whereby the six forward-speed automatic transmission is converted to a three forward-speed automatic transmission when the manual selector valve is shifted to the particular shift position.

  11. Social Ties and Emotions: Evidence from Social Media

    E-print Network

    Lerman, Kristina; Gallegos, Luciano; Kumaraguru, Ponnurangam; Garcia, David

    2015-01-01

    The social connections, or ties, individuals create affect their life outcomes, for example, by providing novel information that leads to new jobs or career opportunities. A host of socioeconomic and cognitive factors are believed to affect social interactions, but few of these factors have been empirically validated. In this research work, we extracted a large corpus of data from a popular social media platform that consists of geo-referenced messages, or tweets, posted from a major US metropolitan area. We linked these tweets to US Census data through their locations. This allowed us to measure emotions expressed in tweets posted from a specific area, and also use that area's socioeconomic and demographic characteristics in the analysis. We extracted the structure of social interactions from the people mentioned in tweets from that area. We find that at an aggregate level, areas where social media users engage in stronger, less diverse online social interactions are those where they express more negative em...

  12. Radio-planetary from tie from Phobos-2 VLBI data

    NASA Technical Reports Server (NTRS)

    Hildebrand, C. E.; Iijima, B. A.; Kroger, P. M.; Folkner, W. M.; Edwards, C. D.

    1994-01-01

    In an ongoing effort to improve the knowledge of the relative orientation (the 'frame tie') of the planetary ephemeris reference frame used in deep navigation and a second reference frame that is defined by the coordinates of a set of extragalactic radio sources, VLBI observations of the Soviet Phobos-2 spacecraft and nearby (in angle) radio sources were obtained at two epochs in 1989, shortly after the spacecraft entered orbit about Mars. The frame tie is an important systematic error source affecting both interplanetary navigation and the process of improving the theory of the Earth's orientation. The data from a single Phobos-2 VLBI session measure one component of the direction vector from Earth to Mars in the frame of the extragalactic radio sources (the 'radio frame'). The radio frame has been shown to be stable and internally consistent with an accuracy of 5 nrad. The planetary ephemeris reference frame has an internal consistency of approximately 15 nrad. The planetary and radio source reference frames were aligned prior to 1989 and measurements of occulations of the radio source 3C273 by the Moon. The Phobos-2 VLBI measurements provide improvement in the accuracy of two of the three angles describing a general rotation between the planetary and radio reference frames. A complete set of measurements is not available because data acquisition was terminated prematurely by loss of spacecraft. The analysis of the two Phobos-2 VLBI data sets indicates that, in the directions of the two rotation components determined by these data, the JPL planetary ephemeris DE200 is aligned with the radio frame as adopted by the International Earth Rotation Service within an accuracy of 20-40 nrad, depending on direction. The limiting errors in the solutions for these offsets are spacecraft trajectory (20 nrad), instrumental biases (19 nrad), and dependence of quasar coordinates on observing frequency (24 nrad).

  13. Software for Verifying Image-Correlation Tie Points

    NASA Technical Reports Server (NTRS)

    Klimeck, Gerhard; Yagi, Gary

    2008-01-01

    A computer program enables assessment of the quality of tie points in the image-correlation processes of the software described in the immediately preceding article. Tie points are computed in mappings between corresponding pixels in the left and right images of a stereoscopic pair. The mappings are sometimes not perfect because image data can be noisy and parallax can cause some points to appear in one image but not the other. The present computer program relies on the availability of a left- right correlation map in addition to the usual right left correlation map. The additional map must be generated, which doubles the processing time. Such increased time can now be afforded in the data-processing pipeline, since the time for map generation is now reduced from about 60 to 3 minutes by the parallelization discussed in the previous article. Parallel cluster processing time, therefore, enabled this better science result. The first mapping is typically from a point (denoted by coordinates x,y) in the left image to a point (x',y') in the right image. The second mapping is from (x',y') in the right image to some point (x",y") in the left image. If (x,y) and(x",y") are identical, then the mapping is considered perfect. The perfect-match criterion can be relaxed by introducing an error window that admits of round-off error and a small amount of noise. The mapping procedure can be repeated until all points in each image not connected to points in the other image are eliminated, so that what remains are verified correlation data.

  14. Automatic transmission

    SciTech Connect

    Aoki, H.

    1989-03-21

    An automatic transmission is described, comprising: a torque converter including an impeller having a connected member, a turbine having an input member and a reactor; and an automatic transmission mechanism having first to third clutches and plural gear units including a single planetary gear unit with a ring gear and a dual planetary gear unit with a ring gear. The single and dual planetary gear units have respective carriers integrally coupled with each other and respective sun gears integrally coupled with each other, the input member of the turbine being coupled with the ring gear of the single planetary gear unit through the first clutch, and being coupled with the sun gear through the second clutch. The connected member of the impeller is coupled with the ring gear of the dual planetary gear of the dual planetary gear unit is made to be and ring gear of the dual planetary gear unit is made to be restrained as required, and the carrier is coupled with an output member.

  15. Vented transmission

    SciTech Connect

    Nguyen, T.H.

    1990-01-29

    This patent describes a vented transmission. It comprises: a housing; a rotary input to the housing; a rotary output from the housing; transmission means within the housing interconnecting the input and the output and including a hollow, rotary shaft journaled within the housing; a vent tube having a first end extending into one end of the hollow shaft and a second end in fluid communication with the exterior of the housing; a shoulder within the hollow shaft and intermediate the ends of the vent tube and defining of relatively smaller diameter section near the first end of the vent tube that is within the hollow shaft and a relatively large diameter section nearer the second end of the vent tube; at least one aperture extending through the hollow shaft from the large diameter section immediately adjacent the shoulder; and a labyrinth seal at the interface of the vent tube and the large diameter section at a location between the aperture (s) and the second end of the vent tube.

  16. Overdrive transmission

    SciTech Connect

    Miller, G.F.

    1986-02-04

    This patent describes an overdrive transmission device for use with a motor vehicle. It consists of: a housing; a driving shaft rotatably mounted within the housing; a planetary gear-train; a driven shaft rotatably mounted in the housing and driven by the planetary gear train; and, a device for selectively connecting the planetary gear carrier to the housing or to the driven shaft for rotation; a hydraulically actuated piston adapted to forcibly contact the clutch friction members of the second clutch; a source of working fluid; a pump in fluid flow communication with the source of working fluid; a first valve downstream of the pump and in fluid flow communication with the pump and the hydraulically activated piston.

  17. Automatic transmission

    SciTech Connect

    Hamane, M.; Ohri, H.

    1989-03-21

    This patent describes an automatic transmission connected between a drive shaft and a driven shaft and comprising: a planetary gear mechanism including a first gear driven by the drive shaft, a second gear operatively engaged with the first gear to transmit speed change output to the driven shaft, and a third gear operatively engaged with the second gear to control the operation thereof; centrifugally operated clutch means for driving the first gear and the second gear. It also includes a ratchet type one-way clutch for permitting rotation of the third gear in the same direction as that of the drive shaft but preventing rotation in the reverse direction; the clutch means comprising a ratchet pawl supporting plate coaxially disposed relative to the drive shaft and integrally connected to the third gear, the ratchet pawl supporting plate including outwardly projection radial projections united with one another at base portions thereof.

  18. Planetary transmission

    SciTech Connect

    Nerstad, K.A.; Windish, W.E.

    1987-04-21

    A planetary transmission is described comprising: an input shaft; a first planetary gear set having a first sun gear driven by the input shaft, a first planet carrier serving as the output, a first ring gear, and first brake means for selectively holding the fist ring gear stationary; a second planetary gear set having a second sun gear driven by the input shaft, a second planet carrier connected for joint rotation to the first ring gear, a second ring gear, and second brake means for selectively holding the second ring gear stationary; a third planetary gear set having a third sun gear connected for joint rotation to the second planet carrier, a third planet carrier connected for joint rotation to the second ring gear, a third ring gear, and third brake means for selectively holding the third ring gear stationary; and clutch means for connecting the third sun gear to the input shaft and providing a direct drive mode of operation.

  19. Aalborg Universitet A Synchronization Method for Single-Phase Grid-Tied Inverters

    E-print Network

    Schwefel, Hans-Peter

    Aalborg Universitet A Synchronization Method for Single-Phase Grid-Tied Inverters Hadjidemetriou). A Synchronization Method for Single-Phase Grid-Tied Inverters. IEEE Transactions on Power Electronics, 31(3), 2139 generation systems to meet the grid codes/standards with respect to power quality and the fault ride through

  20. Genones: Generalized Mixture Tying in Continuous Hidden Markov ModelBased Speech Recognizers

    E-print Network

    Digalakis, Vassilis

    Genones: Generalized Mixture Tying in Continuous Hidden Markov Model­Based Speech Recognizers V modeling resolution and robustness by using a new, general scheme for tying of mixture components in contin­ uous mixture­density hidden Markov model (HMM)­based speech recognizers. The sets of HMM states

  1. Non-Equilibrium and Current Sheet Formation in Line-Tied

    E-print Network

    Ng, Chung-Sang

    Non-Equilibrium and Current Sheet Formation in Line-Tied Magnetic Fields C. S. Ng and A years Require sharp gradient (current sheets) Line-tying in photosphere Quasi-equilibrium --- most equations #12;Magnetostatic equilibrium J z +[A, J] = 0 ,or B J = 0 with = = 0. c.f. 2D Euler equation

  2. Social Features of Online Networks: The Strength of Intermediary Ties in Online Social Media

    E-print Network

    Moro, Esteban

    Social Features of Online Networks: The Strength of Intermediary Ties in Online Social Media Abstract An increasing fraction of today's social interactions occur using online social media) Social Features of Online Networks: The Strength of Intermediary Ties in Online Social Media. PLoS ONE 7

  3. Neural dynamics of social tie formation in economic decision-making.

    PubMed

    Bault, Nadège; Pelloux, Benjamin; Fahrenfort, Johannes J; Ridderinkhof, K Richard; van Winden, Frans

    2015-06-01

    The disposition for prosocial conduct, which contributes to cooperation as arising during social interaction, requires cortical network dynamics responsive to the development of social ties, or care about the interests of specific interaction partners. Here, we formulate a dynamic computational model that accurately predicted how tie formation, driven by the interaction history, influences decisions to contribute in a public good game. We used model-driven functional MRI to test the hypothesis that brain regions key to social interactions keep track of dynamics in tie strength. Activation in the medial prefrontal cortex (mPFC) and posterior cingulate cortex tracked the individual's public good contributions. Activation in the bilateral posterior superior temporal sulcus (pSTS), and temporo-parietal junction was modulated parametrically by the dynamically developing social tie-as estimated by our model-supporting a role of these regions in social tie formation. Activity in these two regions further reflected inter-individual differences in tie persistence and sensitivity to behavior of the interaction partner. Functional connectivity between pSTS and mPFC activations indicated that the representation of social ties is integrated in the decision process. These data reveal the brain mechanisms underlying the integration of interaction dynamics into a social tie representation which in turn influenced the individual's prosocial decisions. PMID:25338630

  4. Engineering for Humanity Global TIES is UC San Diego's innovative humanitarian engineering

    E-print Network

    Gleeson, Joseph G.

    Engineering for Humanity Global TIES is UC San Diego's innovative humanitarian engineering program, 2011, 2012, and 2013. Established in 2004 as TIES ­ Teams in Engineering Service by the renowned Jacobs School of Engineering, the program has designed engineering and technology solutions for Habitat

  5. 78 FR 25303 - Prestressed Concrete Steel Rail Tie Wire From China, Mexico, and Thailand

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Prestressed Concrete Steel Rail Tie Wire From China, Mexico, and Thailand Institution of... materially retarded, by reason of imports from prestressed concrete steel rail tie wire from China,...

  6. 77 FR 21620 - Notice of the Buy America Waiver Request for Vossloh 101-LV Concrete Ties

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... Register published on April 11, 2000 (65 FR 19477), or you may visit http://www.dot.gov/privacy.html... Federal Railroad Administration Notice of the Buy America Waiver Request for Vossloh 101-LV Concrete Ties... requirements for the purchase of Vossloh 101-LV concrete ties, which contain certain components...

  7. 78 FR 37236 - Prestressed Concrete Steel Rail Tie Wire From China, Mexico, and Thailand

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... Commission, Washington, DC, and by publishing the notice in the Federal Register of April 30, 2013 (78 FR... COMMISSION Prestressed Concrete Steel Rail Tie Wire From China, Mexico, and Thailand Determinations On the... injured by reason of imports from China, Mexico, and Thailand of prestressed concrete steel rail tie...

  8. Experimentally Validated Compatibility Strut and Tie Modeling of Reinforced Concrete Bridge Piers 

    E-print Network

    Scott, Reece Melby

    2010-10-12

    A compatibility-based strut-and-tie model C-STM is proposed for analyzing deep beams and disturbed regions with particular emphasis on reinforced concrete bridge piers. In addition to the normal strut-and-tie force equilibrium requirements the model...

  9. 11-level Cascaded H-bridge Grid-tied Inverter Interface with Solar Panels

    E-print Network

    Tolbert, Leon M.

    11-level Cascaded H-bridge Grid-tied Inverter Interface with Solar Panels Faete Filho, Yue Cao multilevel DC-AC grid-tied inverter. Each inverter bridge is connected to a 200 W solar panel. OPAL-RT lab match. A novel SPWM scheme is proposed in this paper to be used with the solar panels that can account

  10. Social Identity, Social Ties and Social Capital: A Study in Gaming Context

    ERIC Educational Resources Information Center

    Jiang, Hao

    2012-01-01

    This work will focus on how different social relationships, namely shared identity and personal tie, will impact cooperative behavior, a form of social capital. I designed and conducted an economic game study to show that shared identity and personal ties work differently on cooperation among people and resource flow in social groups. Many factors…

  11. The use of nylon cable ties to repair rib fractures in neonatal foals.

    PubMed

    Downs, Chris; Rodgerson, Dwayne

    2011-03-01

    Commercially available nylon cable ties were used as a method of internal fixation for displaced rib fractures in 8 equine neonates. The procedure was effective, well-tolerated, rapid, and inexpensive. The use of nylon cable ties as internal fixation for displaced rib fractures in foals is an effective surgical procedure. PMID:21629427

  12. Effects of a Group Intervention on the Career Network Ties of Finnish Adolescents

    ERIC Educational Resources Information Center

    Jokisaari, Markku; Vuori, Jukka

    2011-01-01

    The authors evaluated how a group-based career intervention affected career network ties among Finnish adolescents as they made educational choices and prepared for their transition to secondary education. They examined the career-related network ties of 868 students during their last year in comprehensive school (junior high school) in a…

  13. 46 CFR 112.05-3 - Main-emergency bus-tie.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... other source of electric power, except for interlock systems for momentary transfer of loads; and (c) If... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS General § 112.05-3 Main-emergency bus-tie. Each bus-tie between a main...

  14. 46 CFR 112.05-3 - Main-emergency bus-tie.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... other source of electric power, except for interlock systems for momentary transfer of loads; and (c) If... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS General § 112.05-3 Main-emergency bus-tie. Each bus-tie between a main...

  15. 46 CFR 112.05-3 - Main-emergency bus-tie.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... other source of electric power, except for interlock systems for momentary transfer of loads; and (c) If... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS General § 112.05-3 Main-emergency bus-tie. Each bus-tie between a main...

  16. 46 CFR 112.05-3 - Main-emergency bus-tie.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... other source of electric power, except for interlock systems for momentary transfer of loads; and (c) If... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS General § 112.05-3 Main-emergency bus-tie. Each bus-tie between a main...

  17. 46 CFR 112.05-3 - Main-emergency bus-tie.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... other source of electric power, except for interlock systems for momentary transfer of loads; and (c) If... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS General § 112.05-3 Main-emergency bus-tie. Each bus-tie between a main...

  18. Social support and social interaction ties on internet addiction: integrating online and offline contexts.

    PubMed

    Wang, Edward Shih-Tse; Wang, Michael Chih-Hung

    2013-11-01

    This study explores the relationship between social support and social interaction ties on Internet addiction by integrating both online and offline social encounters. A total of 1,642 members of online social communities participated in this research, for which structural equation modeling was used for analysis. The findings show that social support is positively associated with social interaction ties in both online and offline contexts. In addition, online social support and online social interaction ties are positively associated with Internet addiction, whereas offline social support and social interaction ties on Internet addiction are negatively associated. This finding has important implications not only for understanding the cause of Internet addiction but also for understanding the diminishing Internet addiction due to social support and social interaction ties. PMID:23848959

  19. Tie-In Orbits for the Focal Plane Stability Test

    NASA Astrophysics Data System (ADS)

    Abramowicz-Reed, Linda

    1991-07-01

    This proposal is part of the TTSC request entitled, "Distortion Calibration in FGS 1 and FGS 2, FGS-to-FGS Alignment Calibration". This portion is listed separately due to the time critical nature of one of the orbits. OFAD in FGS 3 which will be performed in December 1992 together with the Mini OFAD's in FGS's 1 and 2 which will be performed in January 1993 will provide a new set of FGS calibration parameters. One of the objectives of the STScI Focal Plane Stability test is to monitor changes to these parameters by repeatedly observing targets in the cluster M35. Since the cluster is near the ecliptic, only two vehicle orientations are needed, the "fall" and the "spring" pointings (see attached pickles plots). Since the Mini OFAD targets are not necessarily the same targets used in the Focal Plane Stability Test, tie in orbits using the Focal Plane Stability targets are needed shortly before and after the Mini OFAD activities. In addition, the Focal Plane Stability Test may not be

  20. Tying dark matter to baryons with self-interactions.

    PubMed

    Kaplinghat, Manoj; Keeley, Ryan E; Linden, Tim; Yu, Hai-Bo

    2014-07-11

    Self-interacting dark matter (SIDM) models have been proposed to solve the small-scale issues with the collisionless cold dark matter paradigm. We derive equilibrium solutions in these SIDM models for the dark matter halo density profile including the gravitational potential of both baryons and dark matter. Self-interactions drive dark matter to be isothermal and this ties the core sizes and shapes of dark matter halos to the spatial distribution of the stars, a radical departure from previous expectations and from cold dark matter predictions. Compared to predictions of SIDM-only simulations, the core sizes are smaller and the core densities are higher, with the largest effects in baryon-dominated galaxies. As an example, we find a core size around 0.3 kpc for dark matter in the Milky Way, more than an order of magnitude smaller than the core size from SIDM-only simulations, which has important implications for indirect searches of SIDM candidates. PMID:25062162

  1. Primary monocytes regulate endothelial cell survival through secretion of Angiopoietin-1 and activation of endothelial Tie2

    E-print Network

    Schubert, Shai Y.

    Objective—Monocyte recruitment and interaction with the endothelium is imperative to vascular recovery. Tie2 plays a key role in endothelial health and vascular remodeling. We studied monocyte-mediated Tie2/angiopoietin ...

  2. Automatic transmission

    SciTech Connect

    Miura, M.; Inuzuka, T.

    1986-08-26

    1. An automatic transmission with four forward speeds and one reverse position, is described which consists of: an input shaft; an output member; first and second planetary gear sets each having a sun gear, a ring gear and a carrier supporting a pinion in mesh with the sun gear and ring gear; the carrier of the first gear set, the ring gear of the second gear set and the output member all being connected; the ring gear of the first gear set connected to the carrier of the second gear set; a first clutch means for selectively connecting the input shaft to the sun gear of the first gear set, including friction elements, a piston selectively engaging the friction elements and a fluid servo in which hydraulic fluid is selectively supplied to the piston; a second clutch means for selectively connecting the input shaft to the sun gear of the second gear set a third clutch means for selectively connecting the input shaft to the carrier of the second gear set including friction elements, a piston selectively engaging the friction elements and a fluid servo in which hydraulic fluid is selectively supplied to the piston; a first drive-establishing means for selectively preventing rotation of the ring gear of the first gear set and the carrier of the second gear set in only one direction and, alternatively, in any direction; a second drive-establishing means for selectively preventing rotation of the sun gear of the second gear set; and a drum being open to the first planetary gear set, with a cylindrical intermediate wall, an inner peripheral wall and outer peripheral wall and forming the hydraulic servos of the first and third clutch means between the intermediate wall and the inner peripheral wall and between the intermediate wall and the outer peripheral wall respectively.

  3. Power transmission

    SciTech Connect

    Ordo, J.P.; Raszkowski, J.A.; Klemen, D.

    1991-04-23

    This patent describes a transmission. It comprises a housing having first and second end covers; an input shaft rotatably mounted in the first end cover; an output shaft rotatably supported on the input shaft and in the second end cover; first and second countershafts rotatably supported in the end covers for rotation on respective axis parallel with the input shaft and the output shaft; a first head gear continuously rotatable with the input shaft; second and third head gears meshing with the first head gear and continuously rotatable with the first and second countershafts respectively; ratio gears rotatably supported on each of the countershafts including a first ratio gear on the first countershaft and a second ratio gear on the second countershaft; reverse gear means including a first ratio gear on the first countershaft and a second ratio gear on the second countershaft; reverse gear means including a first member rotatable with the first ratio gear means including a first member rotatable with the first ratio gear and a second member rotatably supported on the second countershaft; synchronizer clutch means selectively and alternatively connectible with the second ratio gear and the second member of the reverse gear means; output gear means drivingly connected with the output shaft and including a first ratio output gear meshing with the second ratio gear; first selectively engageable friction clutch means for connecting the first ratio gear with the first countershaft for completing a low forward drive ratio between the input and output shafts; and second selectively engageable friction clutch means for selectively connecting the synchronizer clutch means to the second countershaft and cooperating therewith to selectively alternatively complete a reverse drive ratio between the input shaft and the output shaft and another forward drive ratio between the input and output shafts.

  4. Survey of Transmission Cost Allocation Methodologies for Regional Transmission Organizations

    SciTech Connect

    Fink, S.; Porter, K.; Mudd, C.; Rogers, J.

    2011-02-01

    The report presents transmission cost allocation methodologies for reliability transmission projects, generation interconnection, and economic transmission projects for all Regional Transmission Organizations.

  5. Laparoscopic Suturing and Knot Tying: A Comparison of Standard Techniques to a Mechanical Assist Device

    PubMed Central

    Bermas, Honnie; Fenoglio, Michael; Haun, William; Moore, John T.

    2004-01-01

    Background: Suturing and knot tying are basic skills for surgeons. Performing these tasks laparoscopically can be a tedious, time-consuming endeavor associated with much frustration. We evaluated a mechanically assisted suture and pretied knot device (Quik-Stitch) for performing the basic tasks of suturing and knot tying. Methods: We performed a time study using 1) intracorporeal suturing and knot tying, 2) intracorporeal suturing and extracorporeal knot tying, and 3) a mechanically assisted suture and pretied knot device (Quik-Stitch). From September 2000 through March 2001, time trials were conducted using each of the different techniques. Three attending surgeons, one with much experience and 2 with less experience, and 2 chief residents, with the least experience, participated in the study. Results: For the experienced surgeon, the average times for intracorporeal knot tying, extracorporeal knot tying, and knot tying with Quik-Stitch were 97.3, 103.9, and 67.7 seconds, respectively. For the less experienced surgeons, the times were 237.2, 224.3, and 92.5 seconds, respectively. For the least experienced group, the times were 265.3, 263.0, and 128.7 seconds, respectively. Conclusions: The mechanically assisted suture device and pretied knot (Quik-Stitch by PARE Surgical, Inc, Englewood, CO, USA) provides significant time-saving to surgeons regardless of experience and thus reduces operating room costs. Less experienced surgeons and surgeons in training benefited the most by the use of this device. PMID:15119668

  6. Correcting amplitude, time, and phase mis-ties in seismic data

    SciTech Connect

    Bishop, T.N. ); Nunns, A.G. )

    1994-06-01

    Seismic lines from different vintages frequently mis-tie where they intersect. The mis-ties may stem from different amplitudes, a shift in time, or different wave-let character. The authors can correct these mis-ties to a great extent by applying a scale factor, a static time shift, and a phase rotation to one of the lines. The authors describe algorithms to compute the amplitude, time, and phase differences at each intersection among a series of 2-D seismic lines. They can then use an iterative least-squares technique to derive optimal mis-tie corrections for each line. They include a necessary modification of the least-squares technique for the nonlinear phase data. The various algorithms are stable, fast, and accurate. They have used them in conjunction with an interactive workstation seismic interpretation program for five years. The scalar mis-tie corrections greatly enhance the consistency of the seismic data. The authors show the results of the mis-tie package applied to a 20-line survey consisting of five vintages of seismic data. The resulting mis-tie corrections significantly improve the fit between the 20 lines.

  7. Recovery From Radiation-induced Bone Marrow Damage by HSP25 Through Tie2 Signaling

    SciTech Connect

    Lee, Hae-June; Kwon, Hee-Chung; Chung, Hee-Yong; Lee, Yoon-Jin; Lee, Yun-Sil

    2012-09-01

    Purpose: Whole-body radiation therapy can cause severe injury to the hematopoietic system, and therefore it is necessary to identify a novel strategy for overcoming this injury. Methods and Materials: Mice were irradiated with 4.5 Gy after heat shock protein 25 (HSP25) gene transfer using an adenoviral vector. Then, peripheral blood cell counts, histopathological analysis, and Western blotting on bone marrow (BM) cells were performed. The interaction of HSP25 with Tie2 was investigated with mouse OP9 and human BM-derived mesenchymal stem cells to determine the mechanism of HSP25 in the hematopoietic system. Results: HSP25 transfer increased BM regeneration and reduced apoptosis following whole-body exposure to ionizing radiation (IR). The decrease in Tie2 protein expression that followed irradiation of the BM was blocked by HSP25 transfer, and Tie2-positive cells were more abundant among the BM cells of HSP25-transferred mice, even after IR exposure. Following systemic RNA interference of Tie2 before IR, HSP25-mediated radioprotective effects were partially blocked in both mice and cell line systems. Stability of Tie2 was increased by HSP25, a response mediated by the interaction of HSP25 with Tie2. IR-induced tyrosine phosphorylation of Tie2 was augmented by HSP25 overexpression; downstream events in the Tie2 signaling pathway, including phosphorylation of AKT and EKR1/2, were also activated. Conclusions: HSP25 protects against radiation-induced BM damage by interacting with and stabilizing Tie2. This may be a novel strategy for HSP25-mediated radioprotection in BM.

  8. 78 FR 57619 - Prestressed Concrete Steel Rail Tie Wire From Mexico, Thailand, and the People's Republic of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ...A-549-829, A-570-990] Prestressed Concrete Steel Rail Tie Wire From Mexico, Thailand...investigations of imports of prestressed concrete steel rail tie wire from Mexico, Thailand...People's Republic of China. See Prestressed Concrete Steel Rail Tie Wire From Mexico,...

  9. Performance effects of tie-truss modifications for a 70-meter centerline beam waveguide antenna

    NASA Technical Reports Server (NTRS)

    Cucchissi, J. J.

    1989-01-01

    The elevation-axis tie truss of the 70-m antennas would have to be modified to accommodate a centerline beam waveguide. To accomplish this, the center section of the tie truss has to be altered, causing a change in the tie-truss compliance and affecting structural performance. Even with the center section completely removed, the worst-case rms pathlength error due to gravity load is increased from 0.025 to only 0.030 inches. Using a simple postprocessor technique, the effects of modifying the compliance can be predicted without resorting to multiple and costly re-analyses of large finite-element models on a mainframe computer.

  10. Experimental investigation of line-tying effects on the spheromak tilt mode

    SciTech Connect

    Wysocki, F.J.

    1986-02-01

    A variety of passive stabilization techniques compatible with S-1 inductive spheromak formation has been evaluated for effectiveness against the MHD tilting instability. A line-tying stabilization effect has been previously identified theoretically. In the present work, the effects have been experimentally identified and investigated. The perturbed current patterns within passive stabilizing structures have been measured, and line-tying currents have been identified. The simple ring model of tilting has been expanded to include line-tying, and has provided estimates for growth rates which agree well with the measured values. 51 refs., 18 figs., 1 tab.

  11. FDA Warns of Joint Pain Tied to Common Type 2 Diabetes Drugs

    MedlinePLUS

    ... nlm.nih.gov/medlineplus/news/fullstory_154365.html FDA Warns of Joint Pain Tied to Common Type ... are typically high. However, in a statement, the FDA said the medications "may cause joint pain that ...

  12. High 'Resting' Heart Rate Tied to Higher Odds of Early Death

    MedlinePLUS

    ... Heart Rate Tied to Higher Odds of Early Death But more research is needed before this can ... an independent predictor of all-cause and cardiovascular death," said lead researcher Dr. Dongfeng Zhang, of the ...

  13. Comparison of Methods for Evaluating Nuclear Thermal Propulsion Tie-Tube Designs

    SciTech Connect

    Kapernick, Richard J.; Dixon, David D.

    2008-01-21

    One of the fundamental structural components in a nuclear thermal rocket design is the tie tube. Proper cooling and flow modeling is important both for the structural integrity of the reactor core and for proper design of downstream components that operate on the hydrogen exiting the tie tube. Two models have been developed. The first is a spreadsheet-based tool designed for sizing tie-tube components, considering mechanical stress and strain limits, deposited moderator power, thermal expansion along the flow path, and conduction from adjacent fuel blocks. The second is a three-dimensional SINDA/FLUINT model used as a benchmark, containing a complete finite-element fuel block and a 1/6th tie-tube model. This paper discusses the performance of both models, as well as the advantages and limitations of each.

  14. Exposure to BPA in Pregnancy Tied to Low Birth Weight in Girls

    MedlinePLUS

    ... in Pregnancy Tied to Low Birth Weight in Girls: Study But research doesn't prove the chemical ... be linked with low birth weight among baby girls, a new study reports. Mothers with high blood ...

  15. Newborn Probiotic Use Tied to Lower Risk of Type 1 Diabetes

    MedlinePLUS

    ... nih.gov/medlineplus/news/fullstory_155662.html Newborn Probiotic Use Tied to Lower Risk of Type 1 ... 2015 WEDNESDAY, Nov. 11, 2015 (HealthDay News) -- Adding probiotics -- good bacteria -- to an infant's feedings in the ...

  16. Romantic Partnerships and the Dispersion of Social Ties: A Network Analysis of Relationship Status on Facebook

    E-print Network

    Backstrom, Lars

    2013-01-01

    A crucial task in the analysis of on-line social-networking systems is to identify important people --- those linked by strong social ties --- within an individual's network neighborhood. Here we investigate this question for a particular category of strong ties, those involving spouses or romantic partners. We organize our analysis around a basic question: given all the connections among a person's friends, can you recognize his or her romantic partner from the network structure alone? Using data from a large sample of Facebook users, we find that this task can be accomplished with high accuracy, but doing so requires the development of a new measure of tie strength that we term `dispersion' --- the extent to which two people's mutual friends are not themselves well-connected. The results offer methods for identifying types of structurally significant people in on-line applications, and suggest a potential expansion of existing theories of tie strength.

  17. Loads on Tie-Down Systems for Floating Drilling Rigs during Hurricane Conditions 

    E-print Network

    Bae, Yoon Hyeok

    2010-01-16

    Tie-down systems are used to fasten drilling rigs to the deck of offshore structures during harsh environmental conditions such as hurricanes. During Hurricane Ivan (2004) and Katrina (2005), a number of offshore structures were moved and several...

  18. Study Ties Essure Birth Control Implant to Greater Need for Reoperation

    MedlinePLUS

    ... gov/medlineplus/news/fullstory_155119.html Study Ties Essure Birth Control Implant to Greater Need for Reoperation ... 2015 (HealthDay News) -- New research raises concerns about Essure, an implanted long-term birth control device that's ...

  19. CHARACTERIZATION AND ISOLATION OF ORGANIC TOXICANTS IN WHOLE SEDIMENT TOXICITY INDENTIFICATION EVALUATIONS (TIES)

    EPA Science Inventory

    Development of whole sediment toxicity identification and evaluation (TIEs) methods has been under way for approximately four years. These methods are necessary to define cause and effect relationships in toxic sediments during ecological risk assessments, remediation and disposa...

  20. In Rare Cases, Hepatitis C Drug Tied to Slowed Heart Rate

    MedlinePLUS

    ... news/fullstory_155519.html In Rare Cases, Hepatitis C Drug Tied to Slowed Heart Rate: Study But ... the new, highly effective drugs for treating hepatitis C can cause a very slow and erratic heart ...

  1. EFFECTS OF BRINE ADDITION ON EFFLUENT TOXICITY AND MARINE TOXICITY IDENTIFICATION EVALUATION (TIE) MANIPULATIONS

    EPA Science Inventory

    Little information is available concerning the effect of salinity adjustment on effluent storage and toxicity identification evaluation (TIE) performance. hese factors are important for accurate assessments of potential toxicity to marine organisms. he objective of this study was...

  2. Rope and the art of knot-tying in the seafaring of the ancient Eastern Mediterranean 

    E-print Network

    Charlton, William Harrison

    1996-01-01

    Fibers woven into cords or ropes and tied together with knots form one of mankind's earliest tools. When he first went out onto the water on anything more sophisticated than a simple paddle-driven dugout canoe he had to ...

  3. Family ties: representing the relationships between parents and children in contemporary Irish political poetry 

    E-print Network

    Lee, Lori L

    2013-02-22

    In partial fulfillment of the requirements of the UNIVERSITY UNDERGRADUATE RESEARCH FELLOWS April 2000 Group: Humanities FAMILY TIES: REPRESENTING THE RELATIONSHIPS BETWEEN PARENTS AND CHILDREN IN CONTEMPORARY IRISH POLITICAL POETRY A Senior Honors... and content by: Marian Eide (Fellows Advisor) Edward A. Funkhouser (ExecutiveDirector) April 2000 Group: Humanities ABSTRACT Family Ties: Representing the Relationships Between Parents and Children in Contemporary Irish Political Poetry. (April 2000...

  4. Critical considerations for utility/cogeneration inter-tie protection scheme configuration

    SciTech Connect

    Rifaat, R.M.

    1995-09-01

    For inter-ties between cogeneration plants and existing host utility power systems, special considerations must be given to protection systems. The considerations are reviewed in light of contemporary experience with midsize cogenerating plants. Typical inter-tie configurations are deliberated. Implications on the design of protection systems are emphasized. Relevant protection schemes are presented, and their advantages and disadvantages are evaluated. The importance of examining the protection scheme requirements during the conceptual design stage of a cogenerating plant is demonstrated.

  5. Growth rate reduction of the curvature-driven flute instability by plasma blanket line tying

    SciTech Connect

    Segal, D.

    1983-09-01

    The effect of an annular, line-tied blanket, on the curvature-driven flute in a magnetic mirror is considered. The blanket is assumed to be line tied to a thermoionically emitting annular end plate. Reduction of the flute growth rate is computed as function of Larmor radius, blanket radius, and axial plasma conductance through either an external plasma or mirror sheath. It is found that significant reduction in growth rate can be achieved.

  6. Classification and Tie2 mutations in spinal and soft tissue vascular anomalies.

    PubMed

    Zhou, Mei; Jiang, Renbing; Zhao, Gang; Wang, Lisha; Wang, Hua; Li, Wenting; Li, Yiqun; Du, Xiang; Bai, Jingping

    2015-10-15

    Vascular anomalies included hemangiomas and vascular malformations (VMs). VMs are mediated by mutations in the endothelial cell-specific receptor tyrosine kinase Tie2 (TEK),which is essential for angiogenesis and vascular stabilization. We identified five types of Tie2 mutations in 80 patients with soft tissue or spinal VMs by PCR including the previously detected missense mutations 2690A>G (Y897C), 2740C>T (L914F), 2743C>T (R915C), and two nonsense mutations 2763G>A, 2688C>T, we identified Tie2 mutation in primary spinal VMs for the first time. Tie2 mutations were found to be absent in 33 patients with hemangiomas and DNA samples of VMs. In addition, we showed that Tie2 mRNA expression in spinal VMs was similar to soft tissue VMs, but obviously lower than infant hemangiomas (P<0.01). This study provides new insights into spinal VMs, the association of Tie2 and vascular anomalies needs to be further discussed. PMID:26115772

  7. Multi-purpose grid-tied inverter with smart grid capabilities

    NASA Astrophysics Data System (ADS)

    Liyanagedera, Chamika Mihiranga

    Distributed energy storages play an important role in increasing the reliability and efficiency of the grid through means of peak load shaving, grid voltage support, and grid frequency support. It is important to have distributed energy storages that can utilize the functionalities of the modern smart grid to operate more effectively. The grid-tied inverter is one of the major components in a distributed energy storage that controls the power transfer between the grid and an energy storage device. In this research, a grid-tied inverter that can be used in distributed energy storage applications was designed, developed, and tested. This grid-tied inverter was designed with the capability to control both reactive and active power flow in either direction. The grid-tied inverter is equipped with communication capabilities so it can be remotely controlled by commands sent through a smart grid network. For demonstrative purposes, a user interface was developed to control and monitor the operation of the grid-tied inverter. Finally the operation of the grid-tied inverter was evaluated in accordance to IEEE 1547, the Standard for Interconnecting Distributed Resources with Electric Power Systems.

  8. Current Singularities in Line-tied Three-dimensional Magnetic Fields

    NASA Astrophysics Data System (ADS)

    Craig, I. J. D.; Pontin, D. I.

    2014-06-01

    This paper considers the current distributions that derive from finite amplitude perturbations of line-tied magnetic fields comprising hyperbolic field structures. The initial equilibrium on which we principally focus is a planar magnetic X-point threaded by a uniform axial field. This field is line-tied on all surfaces but subject to three-dimensional (3D) disturbances that alter the initial topology. Results of ideal relaxation simulations are presented which illustrate how intense current structures form that can be related, through the influence of line-tying, to the quasi-separatrix layers (QSLs) of the initial configuration. It is demonstrated that the location within the QSL that attracts the current, and its scaling properties, are strongly dependent on the relative dimensions of the QSL with respect to the line-tied boundaries. These results are contrasted with the behavior of a line-tied 3D field containing an isolated null point. In this case, it is found that the dominant current always forms at the null, but that the collapse is inhibited when the null is closer to a line-tied boundary.

  9. $m=1$ Ideal Internal Kink Modes in a Line-tied Screw Pinch

    E-print Network

    Yi-Min Huang; Ellen G. Zweibel; Carl R. Sovinec

    2006-07-17

    It is well known that the radial displacement of the $m=1$ internal kink mode in a periodic screw pinch has a steep jump at the resonant surface where $\\mathbf{k}\\cdot\\mathbf{B}=0$. In a line-tied system, relevant to solar and astrophysical plasmas, the resonant surface is no longer a valid concept. It is then of interest to see how line-tying alters the aforementioned result for a periodic system. If the line-tied kink also produces a steep gradient, corresponding to a thin current layer, it may lead to strong resistive effects even with weak dissipation. Numerical solution of the eigenmode equations shows that the fastest growing kink mode in a line-tied system still possesses a jump in the radial displacement at the location coincident with the resonant surface of the fastest growing mode in the periodic counterpart. However, line-tying thickens the inner layer and slows down the growth rate. As the system length $L$ approaches infinity, both the inner layer thickness and the growth rate approach the periodic values. In the limit of small $\\epsilon\\sim B_{\\phi}/B_{z}$, the critical length for instability $L_{c}\\sim\\epsilon^{-3}$. The relative increase in the inner layer thickness due to line-tying scales as $\\epsilon^{-1}(L_{c}/L)^{2.5}$.

  10. Hydraulic reinforcement of channel at lower tie-plate in BWR fuel bundle

    SciTech Connect

    Johansson, E.B.

    1989-12-26

    This patent describes an apparatus in a fuel bundle for confining fuel rods for the generation of steam in a steam water mixture passing interior of the fuel bundle. The fuel bundle includes: a lower tie-plate for supporting the fuel rods and permitting flow from the lower exterior portion of the fuel bundle into the interior portion of the fuel bundle; a plurality of fuel rods. The fuel rods supported on the lower tie-plate extending upwardly to and towards the upper portion of the fuel bundle for the generation of steam in a passing steam and water mixture interior of the fuel bundle; an upper tie-plate for maintaining the fuel rods in side-by-side relation and permitting a threaded connection between a plurality of the fuel rods with the threaded connection being at the upper and lower tie-plate. The upper tie-plate permitting escape of a steam water mixture from the top of the fuel bundle; a fuel bundle channel; and a labyrinth seal configured in the lower tie-plate.

  11. Ties Matter: Complexity of Manipulation when Tie-breaking with a Random Vote Haris Aziz, Serge Gaspers, Nicholas Mattei, Nina Narodytska, and Toby Walsh

    E-print Network

    Walsh, Toby

    polynomial to NP-hard. We also discuss the relationship with the computational complexity of com- puting than RC. For in- stance, several common scoring rules become NP-hard to manipulate when we tie-break with a random vote. Formal Background A profile is a set of n total orders (votes) over m candi- dates. A voting

  12. Modeling “unilateral” response in the cross-ties of a cable network: Deterministic vibration

    NASA Astrophysics Data System (ADS)

    Giaccu, Gian Felice; Caracoglia, Luca; Barbiellini, Bernardo

    2014-09-01

    Cross-ties are employed as passive devices for the mitigation of stay-cable vibrations, exhibited on cable-stayed bridges under wind and wind-rain excitation. Large-amplitude oscillation can result in damage to the cables or perceived discomfort to bridge users. The “cable-cross-ties system” derived by connecting two or more stays by transverse cross-ties is often referred to as an “in-plane cable network”. Linear modeling of network dynamics has been available for some time. This framework, however, cannot be used to detect incipient failure in the restrainers due to slackening or snapping. A new model is proposed in this paper to analyze the effects of a complete loss in the pre-tensioning force imparted to the cross-ties, which leads to the “unilateral” free-vibration response of the network (i.e., a cross-tie with linear-elastic internal force in tension and partially inactive in compression). Deterministic free vibrations of a three-cable network are investigated by using the “equivalent linearization method”. A performance coefficient is introduced to monitor the relative reduction in the average (apparent) stiffness of the connector during free vibration response (“mode by mode”), exhibiting unilateral behavior. A reduction of fifty percent in the apparent stiffness was observed in the cross-tie when the pre-tensioning force is small in comparison with the tension force in the stay. This coefficient may be used as a damage indicator for the selection of the initial pre-tensioning force in the cross-ties needed to avoid slackening.

  13. Results of Toxicity Identification Evaluations (TIE`S) conducted on the A-01 outfall and its contributory waste streams, July 1996--February 1997

    SciTech Connect

    Specht, W.L.

    1997-03-01

    Toxicity tests were conducted at nine locations during the summer of 1996. The results indicated that A-01B, A-01C, A-03, A-04, A-05 and A-01 were toxic to the test species, Ceriodaphnia dubia, while A-01A, A-06, and WE-01 were not toxic. Beginning in August 1996, Toxicity Identification Evaluations (TIE`s) were initiated on all toxic outfalls in order to identify the toxicants responsible for the observed toxicity. A complete TIE was performed on A-01 because it is the regulatory compliance point for all of the combined waste streams that were tested. Only the portions of a TIE that are related to metal and chlorine toxicity were performed on the remaining locations because existing data indicated that metals and chlorine were present in potentially toxic quantities at these locations, and there was no evidence that other toxicants would be expected to be present in toxic amounts. The results of the TIE`s indicate that metals are responsible for most of the toxicity at all of the outfalls that were toxic and that chlorine contributed to the toxicity at two of the outfalls. Specifically, the toxicity at A-01B, A-01C, and A-01 was due to copper; the toxicity at A-03 was due to primarily to copper, although zinc also contributed to the toxicity; the toxicity at A-04 was due primarily to copper, with residual chlorine and zinc contributing to the toxicity; and the toxicity at A-05 was due primarily to copper, with residual chlorine contributing to the toxicity. A-03 was the most toxic outfall, with 100% mortality occurring at concentrations as low as 12.5% effluent. A-03 was found to have concentrations of copper, lead, and zinc that exceeded EPA water quality criteria by approximately two orders of magnitude. The metal concentrations at A-01 and WE-01, which is located approximately 0.5 miles downstream from A-01 were similar. However, A-01 was toxic, while WE-01 was not.

  14. Variable Somatic TIE2 Mutations in Half of Sporadic Venous Malformations

    PubMed Central

    Soblet, J.; Limaye, N.; Uebelhoer, M.; Boon, L.M.; Vikkula, M.

    2013-01-01

    Venous malformations (VMs) are the most frequent vascular malformations referred to specialized vascular anomaly centers. A rare (1-2%) familial form, termed cutaneomucosal venous malformation (VMCM), is caused by gain-of-function mutations in TIE2. More recently, sporadic VMs, characterized by the presence of large unifocal lesions, were shown to be caused by somatic mutations in TIE2. These include a frequent L914F change, and a series of double mutations in cis. All of which cause ligand-independent receptor hyperphosphorylation in vitro. Here, we expanded our study to assess the range of mutations that cause sporadic VM. To test for somatic changes, we screened the entire coding region of TIE2 in cDNA from resected VMs by direct sequencing. We detected TIE2 mutations in 17/30 (56.7%) of the samples. In addition to previously detected mutations, we identified 7 novel somatic intracellular TIE2 mutations in sporadic VMs, including 3 that cause premature protein truncation. PMID:23801934

  15. Vibration Testing of Electrical Cables to Quantify Loads at Tie-Down Locations

    NASA Technical Reports Server (NTRS)

    Dutson, Joseph D.

    2013-01-01

    The standard method for defining static equivalent structural load factors for components is based on Mile s equation. Unless test data is available, 5% critical damping is assumed for all components when calculating loads. Application of this method to electrical cable tie-down hardware often results in high loads, which often exceed the capability of typical tie-down options such as cable ties and P-clamps. Random vibration testing of electrical cables was used to better understand the factors that influence component loads: natural frequency, damping, and mass participation. An initial round of vibration testing successfully identified variables of interest, checked out the test fixture and instrumentation, and provided justification for removing some conservatism in the standard method. Additional testing is planned that will include a larger range of cable sizes for the most significant contributors to load as variables to further refine loads at cable tie-down points. Completed testing has provided justification to reduce loads at cable tie-downs by 45% with additional refinement based on measured cable natural frequencies.

  16. Community Detection in Signed Networks: the Role of Negative ties in Different Scales.

    PubMed

    Esmailian, Pouya; Jalili, Mahdi

    2015-01-01

    Extracting community structure of complex network systems has many applications from engineering to biology and social sciences. There exist many algorithms to discover community structure of networks. However, it has been significantly under-explored for networks with positive and negative links as compared to unsigned ones. Trying to fill this gap, we measured the quality of partitions by introducing a Map Equation for signed networks. It is based on the assumption that negative relations weaken positive flow from a node towards a community, and thus, external (internal) negative ties increase the probability of staying inside (escaping from) a community. We further extended the Constant Potts Model, providing a map spectrum for signed networks. Accordingly, a partition is selected through balancing between abridgment and expatiation of a signed network. Most importantly, multi-scale spectrum of signed networks revealed how informative are negative ties in different scales, and quantified the topological placement of negative ties between dense positive ones. Moreover, an inconsistency was found in the signed Modularity: as the number of negative ties increases, the density of positive ties is neglected more. These results shed lights on the community structure of signed networks. PMID:26395815

  17. Tie2-Dependent Neovascularization of the Ischemic Hindlimb Is Mediated by Angiopoietin-2

    PubMed Central

    Lekas, Michael; Lekas, Poli; Mei, Shirley H. J.; Deng, Yupu; Dumont, Daniel J.; Stewart, Duncan J.

    2012-01-01

    The angiopoietins (ANGPT) are ligands for the endothelial cell (EC) receptor tyrosine kinase, Tie2. Angpt-1 is a Tie2 agonist that promotes vascular maturation and stabilization, whereas Angpt-2 is a partial agonist/antagonist involved in the initiation of postnatal angiogenesis. Therefore, we hypothesized that overexpression of Angpt-2 would be more effective than Angpt-1 for enhancing the perfusion recovery in the ischemic hindlimb. Perfusion recovery was markedly impaired in Tie2-deficient animals at day 35 in a model of chronic hindlimb ischemia. Injections of Angpt-2 or VEGFA plasmid at 7 days post femoral artery resection enhanced recovery and improved arteriogenesis as assessed by angiographic scores, whereas Angpt-1 or null plasmid had no effect. In addition, Angpt-2 together with VEGF resulted in greater improvement in perfusion and collateral vessel formation than VEGF alone. Similarly, conditional overexpression of Angpt-2 in mice improved ischemic limb blood flow recovery, while Angpt-1 overexpression was ineffective. These data from Tie2 heterozygote deficient mice demonstrate, for the first time, the importance of the Tie2 pathway in spontaneous neovascularization in response to chronic hindlimb ischemia. Moreover, they show that overexpression of the partial agonist, Angpt-2, but not Angpt-1, enhanced ischemic hind limb perfusion recovery and collateralization, suggesting that a coordinated sequence antagonist and agonist activity is required for effective therapeutic revascularization. PMID:23049737

  18. Community Detection in Signed Networks: the Role of Negative ties in Different Scales

    NASA Astrophysics Data System (ADS)

    Esmailian, Pouya; Jalili, Mahdi

    2015-09-01

    Extracting community structure of complex network systems has many applications from engineering to biology and social sciences. There exist many algorithms to discover community structure of networks. However, it has been significantly under-explored for networks with positive and negative links as compared to unsigned ones. Trying to fill this gap, we measured the quality of partitions by introducing a Map Equation for signed networks. It is based on the assumption that negative relations weaken positive flow from a node towards a community, and thus, external (internal) negative ties increase the probability of staying inside (escaping from) a community. We further extended the Constant Potts Model, providing a map spectrum for signed networks. Accordingly, a partition is selected through balancing between abridgment and expatiation of a signed network. Most importantly, multi-scale spectrum of signed networks revealed how informative are negative ties in different scales, and quantified the topological placement of negative ties between dense positive ones. Moreover, an inconsistency was found in the signed Modularity: as the number of negative ties increases, the density of positive ties is neglected more. These results shed lights on the community structure of signed networks.

  19. Community Detection in Signed Networks: the Role of Negative ties in Different Scales

    PubMed Central

    Esmailian, Pouya; Jalili, Mahdi

    2015-01-01

    Extracting community structure of complex network systems has many applications from engineering to biology and social sciences. There exist many algorithms to discover community structure of networks. However, it has been significantly under-explored for networks with positive and negative links as compared to unsigned ones. Trying to fill this gap, we measured the quality of partitions by introducing a Map Equation for signed networks. It is based on the assumption that negative relations weaken positive flow from a node towards a community, and thus, external (internal) negative ties increase the probability of staying inside (escaping from) a community. We further extended the Constant Potts Model, providing a map spectrum for signed networks. Accordingly, a partition is selected through balancing between abridgment and expatiation of a signed network. Most importantly, multi-scale spectrum of signed networks revealed how informative are negative ties in different scales, and quantified the topological placement of negative ties between dense positive ones. Moreover, an inconsistency was found in the signed Modularity: as the number of negative ties increases, the density of positive ties is neglected more. These results shed lights on the community structure of signed networks. PMID:26395815

  20. Transmission control device

    SciTech Connect

    Harada, Y.; Taga, Y.; Nishikawa, S.; Hayakawa, Y.; Kawai, M.

    1987-08-25

    A transmission control device is described having a speed change prohibition time setting function for setting a time wherein speed changing operation is prohibited in accordance with a running state of a vehicle and wherein the control device is used for controlling a transmission system having speed changing ratios and comprises a main transmission and a sub transmission connected to the output shaft of the main transmission. The device consists of: (a) electronic control means for receiving outputs from sensor means for sensing running state of a vehicle; (b) speed changing mechanism driving means controlled by the output from the electronic control means for driving and controlling the speed changing mechanisms in the main transmission and sub transmission; (c) speed change operation detecting means for detecting commencement of the speed change operation of the main transmission and the sub transmission; and (d) speed change prohibition time setting means for prohibiting, after detection of the commencement of the speed changing operation with one of the main and sub transmissions, the speed changing operation of the other of the main and sub transmissions over a predetermined prohibition time which corresponds to a level of a torque input of one of the main and sub transmissions.

  1. The angiopoietin-Tie2 signaling axis in the vascular leakage of systemic inflammation

    PubMed Central

    Milam, Katelyn E; Parikh, Samir M

    2014-01-01

    The ability of small blood vessels to undergo rapid, reversible morphological changes is essential for the adaptive response to tissue injury or local infection. A canonical feature of this response is transient hyperpermeability. However, when leakiness is profound or persistent, adverse consequences accrue to the host, including organ dysfunction and shock. A growing body of literature identifies the Tie2 receptor, a transmembrane tyrosine kinase highly enriched in the endothelium, as an important regulator of vascular barrier function in health and in disease. The principal ligands of Tie2, Angiopoietins 1 and 2, exert opposite effects on this receptor in the context of inflammation. This review will focus on recent studies that have illuminated novel aspects of the exquisitely controlled Tie2 signaling axis while proposing unanswered questions and future directions for this field of study. PMID:25838975

  2. Exploring the Academic Benefits of Friendship Ties for Latino Boys and Girls*

    PubMed Central

    Riegle-Crumb, Catherine; Callahan, Rebecca M.

    2010-01-01

    Objectives We examine how the racial/ethnic and generational status composition of Latino students' friendship groups is related to their academic achievement and whether there are differential effects by gender. Methods We use multivariate regression analyses to examine the effects of friends' characteristics on Latino students' end of high school grades, utilizing data from the Adolescent Health and Academic Achievement Study (AHAA), and its parent survey, the National Longitudinal Study of Adolescent Health (Add Health). Results For Latina girls, there are positive effects of having more friendship ties to third-plus-generation Latino peers in contrast to dominant culture peers; yet Latino boys benefit academically from ties to all co-ethnic peers. Having friends with higher parental education promotes achievement of both genders. Conclusion Our results counter notions of a pervasive negative peer influence of minority youth and suggest that co-ethnic ties are an important source of social capital for Latino students' achievement. PMID:20333266

  3. Quantifying the impact of weak, strong, and super ties in scientific careers

    E-print Network

    Petersen, Alexander Michael

    2015-01-01

    Scientists are frequently faced with the important decision to start or terminate a creative partnership. This process can be influenced by strategic motivations, as early career researchers are pursuers, whereas senior researchers are typically attractors, of new collaborative opportunities. Focusing on the longitudinal aspects of scientific collaboration, we analyzed 473 collaboration profiles using an ego-centric perspective which accounts for researcher-specific characteristics and provides insight into a range of topics, from career achievement and sustainability to team dynamics and efficiency. From more than 166,000 collaboration records, we quantify the frequency distributions of collaboration duration and tie-strength, showing that collaboration networks are dominated by weak ties characterized by high turnover rates. We use analytic extreme-value thresholds to identify a new class of indispensable `super ties', the strongest of which commonly exhibit >50% publication overlap with the central scienti...

  4. Influence of social ties to environmentalists on public climate change perceptions

    NASA Astrophysics Data System (ADS)

    Tindall, D. B.; Piggot, Georgia

    2015-06-01

    An emerging body of research proposes that climate change concern is shaped by one's social ties and cultural milieu. This work aligns with findings in the well-established field of social network analysis, whereby individuals are understood as being embedded in social networks, and network position can be used to predict attitudes. Here we examine whether having ties to environmental movement organization members is correlated with climate change attitudes amongst the general public. We use data from a nationwide survey of the Canadian public to demonstrate that having social ties to environmental organization members increases the likelihood that an individual member of the public has a plan to deal with climate change. These findings reinforce the value of focusing on social context when examining climate change attitudes, and highlight the role that environmental organization members play in mobilizing climate change responses.

  5. A determination of the radio-planetary frame tie and the DSN tracking station locations

    NASA Technical Reports Server (NTRS)

    Finger, Mark H.; Folkner, William M.

    1990-01-01

    The orientation of the reference frame of radio source catalogs relative to that of planetary ephemerides is uncertain by 30 mas (150 nrad). At this level of uncertainty this orientation offset, or 'frame tie', can be a major systematic error source for interplanetary spacecraft orbit determination. This work presents a method of determining the radio-planetary frame tie from a comparison of Very Long Baseline Interferometry (VLBI) and Lunar Laser Ranging (LLR) station coordinate and earth orientation parameter estimates. Preliminary results are presented which indicate that accuracies of 5 mas or better may be achieved with this method. An important by-product of this method of frame tie determination is a set of Deep Space Network (DSN) station locations with 10 cm per component accuracy. This station set is in a geocentric coordinate system with known orientation relative to the radio and planetary frames.

  6. A Community of Strangers: The Dis-Embedding of Social Ties

    PubMed Central

    Parigi, Paolo; State, Bogdan; Dakhlallah, Diana; Corten, Rense; Cook, Karen

    2013-01-01

    In this paper we explore two contrasting perspectives on individuals' participation in associations. On the one hand, some have considered participation the byproduct of pre-existing friendship ties — the more friends one already has in the association, the more likely he or she is to participate. On the other hand, some have considered participation to be driven by the association's capacity to form new identities — the more new friends one meets in the association, the more likely he or she is to participate. We use detailed temporal data from an online association to adjudicate between these two mechanisms and explore their interplay. Our results show a significant impact of new friendship ties on participation, compared to a negligible impact of pre-existing friends, defined here as ties to other members formed outside of the organization's context. We relate this finding to the sociological literature on participation and we explore its implications in the discussion. PMID:23861761

  7. Continuity and Change in Grandchildren’s Closeness to Grandparents: Consequences of Changing Intergenerational Ties

    PubMed Central

    Monserud, Maria A.

    2010-01-01

    Drawing on data from Waves 2 and 3 of the National Survey of Families and Households, this study examines whether grandchildren’s (N = 496) previous patterns of closeness to grandparents is associated with their current closeness to grandparents and whether changes in parents’ intergenerational ties make a difference in the development of grandchildren’s closeness to grandparents when grandchildren experience young adulthood. The findings suggest that there is a possibility for both continuity and change in grandchildren’s bond to grandparents. Grandchildren’s closeness to grandparents was associated not only with their earlier patterns of closeness to grandparents and with parents’ concurrent relations with the grandchild and grandparent generations, but also with changes in parents’ intergenerational ties over time. Also, the grandchild gender moderated linkages between certain intergenerational ties in the family. PMID:21344061

  8. Discovery of Novel Benzimidazoles as Potent Inhibitors of TIE-2 and VEGFR-2 Tyrosine Kinase Receptors

    SciTech Connect

    Hasegawa, Masaichi; Nishigaki, Naohiko; Washio, Yoshiaki; Kano, Kazuya; Harris, Philip A.; Sato, Hideyuki; Mori, Ichiro; West, Rob I.; Shibahara, Megumi; Toyoda, Hiroko; Wang, Liping; Nolte, Robert T.; Veal, James M.; Cheung, Mui

    2008-09-12

    We herein disclose a novel chemical series of benzimidazole-ureas as inhibitors of VEGFR-2 and TIE-2 kinase receptors, both of which are implicated in angiogenesis. Structure-activity relationship (SAR) studies elucidated a critical role for the N1 nitrogen of both the benzimidazole (segment E) and urea (segment B) moieties. The SAR results were also supported by the X-ray crystallographic elucidation of the role of the N1 nitrogen and the urea moiety when the benzimidazole-urea compounds were bound to the VEGFR-2 enzyme. The left side phenyl ring (segment A) occupies the backpocket where a 3-hydrophobic substituent was favored for TIE-2 activity.

  9. Knot-tying with visual and force feedback for VR laparoscopic training.

    PubMed

    Wang, F; Burdet, E; Vuillemin, R; Bleuler, H

    2005-01-01

    Real-time simulation of thread and knot-tying with visual and force feedback is an essential part of virtual reality laparoscopic training. This paper presents a physics-based thread simulator that enables realistic knot tying at haptic rendering rate. The virtual thread follows Newton's law and behaves naturally. The model considers main mechanical properties of the real thread such as stretching, compressing, bending and twisting, as well as contact forces due to self-collision and interaction with the environment, and the effect of gravity. The structure of the system has essential advantages over geometrically based approaches, as was illustrated in an implementation on the Xitact simulator. PMID:17281571

  10. Equation-of-State Based Tie-Simplex Parameterization for Multiphase Thermal-Compositional Simulation

    NASA Astrophysics Data System (ADS)

    Iranshahr, A.; Voskov, D.; Tchelepi, H. A.

    2011-12-01

    Enhanced Oil Recovery (EOR) processes usually involve complex phase behaviors between the injected fluid (e.g., steam, hydrocarbon, CO2, sour) and the in-situ rock-fluid system. Several fundamental questions remain regarding equation-of-state computations for mixtures than can form three, or more, phases at equilibrium. In addition, numerical and computational issues related to proper coupling of the thermodynamic phase-behavior with multiphase flow multi-component transport must be resolved in order to model the behaviors of large-scale EOR processes accurately and efficiently. We describe a general negative-flash method for multi-component, thermal systems that can form three, or more, fluid phases. We prove that the new method is convergent to the unique solution. Based on our multiphase negative-flash technique, we have developed an adaptive tie-simplex parameterization framework for thermal-compositional simulation. We also prove that the tie-simplexes change continuously as a function of pressure, temperature, and composition. The continuity of the parameterized compositional space allows for interpolation in pressure and temperature using a limited number of tie-simplexes. We show that the tie-simplex framework constrains thermodynamic computations, and converges to the global minimum of the Gibbs free energy. The extended negative-flash approach accounts rigorously for tie-simplex degeneration (critical behavior) across phase boundaries. We study the behaviors of thermal-compositional reservoir displacement processes across a wide range of fluid mixtures, pressures, and temperatures. The focus is on the complex behaviors of the tie-triangles and tie-lines associated with three-phase, thermal steam-injection problems in heterogeneous formations. The algorithms that capture the complex combinations of the appearance and disappearance of multiple phases are described in detail. This tie-simplex based parameterization framework is integrated with a general-purpose reservoir simulator, and its accuracy and computational efficiency is demonstrated for several challenging compositional (CO2, four phase sour-gas) and thermal-compositional (steam) models. The nonlinear behaviors are analyzed in terms of the particular displacement process, miscible/immiscible dynamics, number of components, and sensitivity to time step size.

  11. Automated manual transmission controller

    DOEpatents

    Lawrie, Robert E. (Whitmore Lake, MI); Reed, Jr., Richard G. (Royal Oak, MI); Bernier, David R. (Rochester Hills, MI)

    1999-12-28

    A powertrain system for a hybrid vehicle. The hybrid vehicle includes a heat engine, such as a diesel engine, and an electric machine, which operates as both an electric motor and an alternator, to power the vehicle. The hybrid vehicle also includes a manual-style transmission configured to operate as an automatic transmission from the perspective of the driver. The engine and the electric machine drive an input shaft which in turn drives an output shaft of the transmission. In addition to driving the transmission, the electric machine regulates the speed of the input shaft in order to synchronize the input shaft during either an upshift or downshift of the transmission by either decreasing or increasing the speed of the input shaft. When decreasing the speed of the input shaft, the electric motor functions as an alternator to produce electrical energy which may be stored by a storage device. Operation of the transmission is controlled by a transmission controller which receives input signals and generates output signals to control shift and clutch motors to effect smooth launch, upshift shifts, and downshifts of the transmission, so that the transmission functions substantially as an automatic transmission from the perspective of the driver, while internally substantially functioning as a manual transmission.

  12. Bordetella pertussis transmission.

    PubMed

    Trainor, Elizabeth A; Nicholson, Tracy L; Merkel, Tod J

    2015-11-01

    Bordetella pertussis and B. bronchiseptica are Gram-negative bacterial respiratory pathogens. Bordetella pertussis is the causative agent of whooping cough and is considered a human-adapted variant of B. bronchiseptica. Bordetella pertussis and B. bronchiseptica share mechanisms of pathogenesis and are genetically closely related. However, despite the close genetic relatedness, these Bordetella species differ in several classic fundamental aspects of bacterial pathogens such as host range, pathologies and persistence. The development of the baboon model for the study of B. pertussis transmission, along with the development of the swine and mouse model for the study of B. bronchiseptica, has enabled the investigation of different aspects of transmission including the route, attack rate, role of bacterial and host factors, and the impact of vaccination on transmission. This review will focus on B. pertussis transmission and how animal models of B. pertussis transmission and transmission models using the closely related B. bronchiseptica have increased our understanding of B. pertussis transmission. PMID:26374235

  13. Between-group behaviour in health care: gaps, edges, boundaries, disconnections, weak ties, spaces and holes. A systematic review

    PubMed Central

    2010-01-01

    Background Gaps are typically regarded as a problem to be solved. People are stimulated to close or plug them. Researchers are moved to fill deficits in the literature in order to realise a more complete knowledge base, health authorities want to bridge policy-practice disconnections, managers to secure resources to remedy shortfalls between poor and idealised care, and clinicians to provide services to patients across the divides of organisational silos. Despite practical and policy work in many health systems to bridge gaps, it is valuable to study research examining them for the insights provided. Structural holes, spaces between social clusters and weak or absent ties represent fissures in networks, located in less densely populated parts of otherwise closely connected social structures. Such gaps are useful as they illustrate how communication potentially breaks down or interactivity fails. This paper discusses empirical and theoretical work on this phenomenon with the aim of analysing a specific exemplar, the structures of silos within health care organisations. Methods The research literature on social spaces, holes, gaps, boundaries and edges was searched systematically, and separated into health [n = 13] and non-health [n = 55] samples. The health literature was reviewed and synthesised in order to understand the circumstances between stakeholders and stakeholder groups that both provide threats to networked interactions and opportunities to strengthen the fabric of organisational and institutional inter-relationships. Results The research examples illuminate various network structure characteristics and group interactions. They explicate a range of opportunities for improved social and professional relations that understanding structural holes, social spaces and absent ties affords. A principal finding is that these kinds of gaps illustrate the conditions under which connections are strained or have been severed, where the limits of integration between groups occurs, the circumstances in which social spaces are or need to be negotiated and the way divides are bridged. The study's limitations are that it is bounded by the focus of attention and the search terms used and there is yet to be developed a probabilistic, predictive model for gaps and how to connect them. Conclusions Gaps offer insights into social structures, and how real world behaviours of participants in workplaces, organisations and institutions are fragile. The paper highlights the circumstances in which network disjunctures and group divides manifest. Knowledge of these phenomenon provides opportunities for working out ways to improve health sector organisational communications, knowledge transmission and relationships. PMID:21134295

  14. Growing Closer on Facebook: Changes in Tie Strength Through Social Network Site Use

    E-print Network

    Growing Closer on Facebook: Changes in Tie Strength Through Social Network Site Use Moira Burke Facebook mburke@fb.com Robert Kraut Human-Computer Interaction Institute Carnegie Mellon University robert Facebook, whether those sites displace more meaningful interaction, or whether they simply reflect existing

  15. The role of strong and weak ties in Facebook: a community structure perspective

    E-print Network

    Ferrara, Emilio

    The role of strong and weak ties in Facebook: a community structure perspective Emilio Ferrara of the well-known Facebook network. In particular, we discuss the quantitative assessment of the strength-scale online social network such as Facebook. Complex networks, Social network analysis, Community structure

  16. On Facebook, Most Ties are Weak The emergence of pervasive socio-technical networks brings new

    E-print Network

    Ferrara, Emilio

    On Facebook, Most Ties are Weak Abstract The emergence of pervasive socio-technical networks brings's theory can be extended to online social networks like Facebook, suggesting to use interaction data requires knowledge of the topology of the social network, e.g., who is friend with whom on Facebook. Our

  17. The ties that bind: genetic relatedness predicts the fission and fusion of social groups in

    E-print Network

    Alberts, Susan C

    . Here, we test the hypothesis that genetic relatedness predicts patterns of group fission and fusion found that genetic relatedness predicted group fission; adult females remained with their first orderThe ties that bind: genetic relatedness predicts the fission and fusion of social groups in wild

  18. SEAL --Tying Up Information Integration and Web Site Management by Ontologies

    E-print Network

    Staab, Steffen

    SEAL -- Tying Up Information Integration and Web Site Management by Ontologies ¾ Alexander Maedche in- formation sources and they require an adequate web site management system. SEAL (SEmantic port as for web site management. We describe the SEAL conceptual architecture as well as its current

  19. The social nature of the mother's tie to her child: John Bowlby's theory of attachment in

    E-print Network

    Vicedo, Marga

    The social nature of the mother's tie to her child: John Bowlby's theory of attachment in post. In a 1951 report for the World Health Organization Bowlby contended that the mother is the child's psychic organizer, as observational studies of children worldwide showed that absence of mother love had disastrous

  20. Positive Cross-Regulatory Loop Ties GATA-3 to Estrogen Receptor A Expression in Breast Cancer

    E-print Network

    Brown, Myles

    Positive Cross-Regulatory Loop Ties GATA-3 to Estrogen Receptor A Expression in Breast Cancer Je, the functional role of GATA-3 in ERA- positive breast cancers is yet to be established. Here, we show that GATA-3 is required for estradiol stimulation of cell cycle progression in breast cancer cells. The role of GATA-3

  1. Tying the Yellow Ribbon: How School Psychologists and Educators Can Support Military Families

    ERIC Educational Resources Information Center

    Anweiler, Justin

    2008-01-01

    Tying a yellow ribbon around the tree in one's front yard or placing a magnet on one's car is more than just a show of support. It is a promise to American military around the world that one is ready and able to support them in their time of need just as they have supported the country. Educators, including school psychologists, are especially…

  2. Project TIES: Towards Inclusion in Early Settings Model Demonstration Project. Final Report.

    ERIC Educational Resources Information Center

    Willis, Clarissa A.

    This final report describes the activities and outcomes of Project TIES (Towards Inclusion in Early Education), a federally funded demonstration model training program designed to enhance the abilities of child care providers and trainers to include young children, birth to five, with disabilities in developmentally appropriate child care…

  3. TOXICITY REDUCTION AND TOXICITY IDENTIFICATION EVALUATIONS (TIE) FOR EFFLUENTS, AMBIENT WATERS AND OTHER AQUEOUS MEDIA

    EPA Science Inventory

    This publication is the result of a workshop and it is intended for publication through the SETAC Special Publication Series based on the proceedings from the SETAC sponsored workshop that was titles "Toxicity Identification Evaluation (TIE) Forum: What Works, What Doesn't, ...

  4. Design and Calibration of Chambers for Measuring Ammonia Emissions from Tie-stall Dairy Barns

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Dairy barns are thought to emit large amounts of ammonia, which can have detrimental effects on human health and natural ecosystems. In the U.S., relatively little is known about the processes that affect the rate and magnitude of ammonia emissions from dairy barns. The end of a conventional tie-sta...

  5. o blind people develop superior abili-ties in auditory perception to compen-

    E-print Network

    D o blind people develop superior abili- ties in auditory perception to compen- sate for their lack or to voices. Here we show that blind people are better than sighted con- trols at judging the direction by the controls -- but only if they became blind at an early age. The younger the onset of blindness, the better

  6. Heart Defects in Gulf Tuna Seen Tied to 2010 BP Oil Spill

    E-print Network

    Grosell, Martin

    Heart Defects in Gulf Tuna Seen Tied to 2010 BP Oil Spill By Jim Efstathiou Jr. Mar 25, 2014 12 exposed tuna larvae raised in land-based hatcheries to oil collected at the time of the spill:00 AM ET Photographer: Gerard Soury Atlantic Bluefin Tuna. Crude oil from BP Plc (BP/)'s 2010 Gulf

  7. Exploring relationship between human mobility and social ties: Physical distance is not dead

    NASA Astrophysics Data System (ADS)

    Jin, Bo; Liao, Binbing; Yuan, Ning; Wang, Wenjun

    2015-06-01

    Partly due to the difficulty of the access to a worldwide dataset that simultaneously captures the location history and social networks, our understanding of the relationship between human mobility and the social ties has been limited. However, this topic is essential for a deeper study from human dynamics and social networks aspects. In this paper, we examine the location history data and social networks data of 712 email users and 399 offline events users from a map-editing based social network website. Based on these data, we expand all our experiment both from individual aspect and community aspect. We find that the physical distance is still the most influential factor to social ties among the nine representative human mobility features extracted from our GPS trajectory dataset, although Internet revolution has made long-distance communication dramatically faster, easier and cheaper than ever before, and in turn, partly expand the physical scope of social networks. Furthermore, we find that to a certain extent, the proximity of South-North direction is more influential than East-West direction to social ties. To the our best of our knowledge, this difference between South-North and East-West is the first time to be raised and quantitatively supported by a large dataset. We believe our findings on the interplay of human mobility and social ties offer a new perspective to this field of study.

  8. 10 CFR 71.45 - Lifting and tie-down standards for all packages.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., or must be designed with strength equivalent to that required for lifting attachments. (b) Tie-down... component of 2 times the weight of the package with its contents, a horizontal component along the direction in which the vehicle travels of 10 times the weight of the package with its contents, and...

  9. Treatment of Complex Fistula in Ano with Cable-Tie Seton: A Prospective Case Series

    PubMed Central

    Memon, Ayaz Ahmad; Murtaza, Ghulam; Azami, Rizwan; Zafar, Hasnain; Chawla, Tabish; Laghari, Altaf Ali

    2011-01-01

    Objective. To determine the fecal incontinence and recurrence rate in patients with complex fistula in ano managed with cable tie seton at a tertiary care teaching hospital. Methods. This is a prospective case series of patients with complex anal fistula i.e. recurrent fistula or encircling >30% of external anal sphincter, managed with cable tie seton from March 2003 to March 2009. Patients were seen in the clinic after 72 hours of seton insertion under anesthesia and then every other week. Each time the cable-tie was tightened if found loose without anesthesia and incontinence was inquired according to wexner's score. Results. Seventy nine patients were treated during the study period with the age (mean ± standard deviation) of 41 ± 10.6 years and. The seton was tightened with a median of six times (3–15 times range). Complete healing was achieved in 11.2 ± 5.7 weeks. All the patients were followed for a minimum period of one year and none of the patients had any incontinence. Recurrence was found in 4 (5%) patients. Conclusion. The cable tie seton is safe, cost effective and low morbidity option for the treatment of complex fistulae-in-ano. It can, therefore, be recommended as the standard of treatment for complex fistulae-in-ano requiring the placement of a seton. PMID:22084768

  10. Vol 437|8 September 2005 No hormonal response in tied fights

    E-print Network

    Vol 437|8 September 2005 207 No hormonal response in tied fights Fish androgens may start to surge increased in cichlid fish (Oreochromis mossambicus) that are fighting their own image in a mirror, despite triggered in male contests is not induced under these circumstances by the act of fighting itself

  11. Place of Origin, Types of Ties, and Support Networks in Mexico-U.S. Migration

    ERIC Educational Resources Information Center

    Flores-Yeffal, Nadia Y.; Aysa-Lastra, Maria

    2011-01-01

    Previous studies explored how urban or rural place of origin influences the source of social capital. There remains a need to consider how the place of origin affects the type of ties--family, friends, or "paisanos" (countrymen)--with those who provide support to migrants. We use data from the Mexican Migration Project (MMP128) and perform…

  12. An Agent Model for a Human's Social Support Network Tie Preference during Depression

    E-print Network

    Treur, Jan

    An Agent Model for a Human's Social Support Network Tie Preference during Depression Azizi A. Aziz}@few.vu.nl Abstract Seeking support from their environment is important for people suffering from a depression. People. Keywords: depression, social support networks preference, simulation model 1. INTRODUCTION Depression

  13. The Attributional Responses of Young Female Athletes after Winning, Tying, and Losing.

    ERIC Educational Resources Information Center

    Scanlan, Tara K.; Passer, Michael W.

    1980-01-01

    This study examined the attributions of female athletes for their personal and their team's performance after winning, tying, and losing a competitive soccer game. Players' attributions were made to the internal factors of ability and effort and to the external factors of opponent difficulty and luck. (Authors/CJ)

  14. A Smart Machine Vision System for PCB Inspection Tie Qi Chen1

    E-print Network

    Lu, Yi

    A Smart Machine Vision System for PCB Inspection Tie Qi Chen1 , JianXin Zhang1 , YouNing Zhou2 board (PCB) inspection. It has advantages over the traditional manual inspection by its higher of a PCB board. The OLI module runs on-line to inspect PCB boards using a high-resolution 2-D sensor

  15. Non-Equilibrium and Current Sheet Formation in Line-Tied

    E-print Network

    Ng, Chung-Sang

    Non-Equilibrium and Current Sheet Formation in Line-Tied Magnetic Fields: Heating of the Solar in a magnetic non-equilibrium Parker's model (1972): Non-equilibrium driven by complex photospheric motions. i.e. surfaces of tangential discontinuities separating regions of quasi-equilibrium · Photospheric motion has

  16. Tongue-Tied: The Lives of Multilingual Children in Public Education

    ERIC Educational Resources Information Center

    Santa Ana, Otto

    2004-01-01

    Tongue-Tied is an anthology that gives voice to millions of people who, on a daily basis, are denied the opportunity to speak in their own language. First-person accounts by Amy Tan, Sherman Alexie, Bell Hooks, Richard Rodriguez, Maxine Hong Kingston, and many other authors open windows into the lives of linguistic minority students and their…

  17. Social Tie Characteristics and Psychiatric Rehabilitation Outcomes among Adults with Serious Mental Illness

    ERIC Educational Resources Information Center

    Chou, Chih-Chin; Chronister, Julie Ann

    2012-01-01

    Social support has achieved national attention as a key component of the mental health recovery paradigm for persons with serious mental illness (SMI). The aim of this study was to investigate the amount of variance accounted for by four social tie characteristics (social network orientation, emotional support, tangible support, and negative…

  18. A Fuzzy Intelligent System for End-of-Line Test , Tie-Qi Chen1

    E-print Network

    Lu, Yi

    The success of the U.S. motor vehicle industry very much depends on the quality of the products it produces to imprecision in system data. Collected data is often unreliable due to inconsistencies in manufacturingA Fuzzy Intelligent System for End-of-Line Test Yi Lu1 , Tie-Qi Chen1 , Jianxin Zhang1 , Jacob

  19. Department Bent Grant Rules, GAO Finds. Award Tied to Bennett's Former Firm Questioned

    ERIC Educational Resources Information Center

    Davis, Michelle R.

    2006-01-01

    The U.S. Department of Education (DOE) bypassed its own policies when officials awarded a grant early in President Bush's first term that benefited a company founded by former Secretary of Education William J. Bennett, as well as others to groups with close ties to the administration, federal auditors have concluded. The Government Accountability…

  20. Children in Residential Group Care with No Family Ties: Facing Existential Aloneness

    ERIC Educational Resources Information Center

    Dvir, Orly; Weiner, Anita; Kupermintz, Hagai

    2012-01-01

    The issue of children living in residential group care in Israel completely without family ties is studied in order to explore the feelings of staff and uncover possible characteristics of these children. Data were collected through focus groups, questionnaires, and life stories of children who left group care at 18 years of age. Results reveal…

  1. CONTEXT DEPENDENT STATE TYING FOR SPEECH RECOGNITION USING DEEP NEURAL NETWORK ACOUSTIC MODELS

    E-print Network

    Cortes, Corinna

    or as a feature extrac- tor, there is a clear determination in the field to keep using neural network the neural network is used as a feature extrac- tor alone. Hence there is an interest in removingCONTEXT DEPENDENT STATE TYING FOR SPEECH RECOGNITION USING DEEP NEURAL NETWORK ACOUSTIC MODELS

  2. Fabrication and Characterization of Porous Sintered TieAg Compacts for Biomedical Application Purpose

    E-print Network

    Zheng, Yufeng

    , raw powders and stainless steel balls (6 mm in diameter) in a weight ratio of 1:10 were put (purity, 99.4%) and Ag powder (purity, 99.9%) were the raw materials for preparing TieAg compacts. First into stainless steel containers with the protection of Ar atmosphere. And then the containers were milled

  3. 78 FR 75545 - Prestressed Concrete Steel Rail Tie Wire From the People's Republic of China: Preliminary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ... China, and Thailand: Initiation of Antidumping Duty Investigations, 78 FR 29325, 29330 (May 20, 2013... Countervailing Duty Investigations, 76 FR 61042 (October 3, 2011). International Trade Commission (``ITC... International Trade Administration Prestressed Concrete Steel Rail Tie Wire From the People's Republic of...

  4. FUTURE FORCE AND FIRST RESPONDERS: BUILDING TIES FOR COLLABORATION AND LEVERAGED RESEARCH AND DEVELOPMENT

    E-print Network

    Hammer, Joachim

    and training. A white paper states Future Force will "see first, understand first, act first, and finish1 FUTURE FORCE AND FIRST RESPONDERS: BUILDING TIES FOR COLLABORATION AND LEVERAGED RESEARCH are similar to those for First Responders who comprise the backbone of Homeland Security personnel

  5. Newspaper Readership and Community Ties; Precision Journalism: Coming of Age. ANPA News Research Report No. 18.

    ERIC Educational Resources Information Center

    Stevenson, Robert L.; Ismach, Arnold H.

    The first of two articles in this report offers a survey of how community ties lead to various psychological needs that are the motivation for newspaper reading. It identifies three distinct audience segments: the traditional audience, with permanent bonds to the community, whose need for information, guidance, and community surveillance leads to…

  6. Local search for stable marriage problems with ties and incomplete lists

    E-print Network

    Rossi, Francesca

    Local search for stable marriage problems with ties and incomplete lists M. Gelain1 , M. S. Pini1, Australia, Email: Toby.Walsh@nicta.com.au Abstract. The stable marriage problem has a wide variety, or more generally to any two-sided market. We consider a useful variation of the stable marriage problem

  7. Social stress, locality of social ties and mental well-being: the case of rural migrant adolescents in urban China.

    PubMed

    Cheung, Nicole W T

    2014-05-01

    By comparing rural migrant and urban native adolescents in Guangzhou, the largest city in south China, this study investigated the relationships between social stress, social ties that link migrants to their host cities (local ties) and to their rural home communities (trans-local ties), and the migrants? mental well-being. Non-migration social stress was more strongly related to poor psychological health than to weak self-efficacy in both migrant and urban native adolescents. This pattern also applied to the effect of migration-specific assimilation stress on psychological health and self-efficacy in migrants. Social ties directly enhanced these two well-being outcomes in both samples, with the effects of trans-local and local ties proving equally potent among migrants. Trans-local ties were somewhat more useful for migrants in moderating the effects of non-migration social stress and assimilation stress, whereas the stress moderation function of social ties was less pronounced in urban natives. These findings extend the migration, network and social stress literature by identifying how local and trans-local ties protect mental health and mitigate stress in migrants. PMID:24607873

  8. Finite element analyses of continuous filament ties for masonry applications:final report for the Arquin Corporation.

    SciTech Connect

    Quinones, Armando; Bibeau, Tiffany A.; Ho, Clifford Kuofei

    2006-06-01

    Finite-element analyses were performed to simulate the response of a hypothetical masonry shear wall with and without continuous filament ties to various lateral loads. The loads represented three different scenarios: (1) 100 mph wind, (2) explosive attack, and (3) an earthquake. In addition, a static loading analysis and cost comparison were performed to evaluate optimal materials and designs for the spacers affixed to the filaments. Results showed that polypropylene, ABS, and polyethylene (high density) were suitable materials for the spacers based on performance and cost, and the short T-spacer design was optimal based on its performance and functionality. Results of the shear-wall loading simulations revealed that simulated walls with the continuous filament ties yielded factors of safety that were at least ten times greater than those without the ties. In the explosive attack simulation (100 psi), the simulated wall without the ties failed (minimum factor of safety was less than one), but the simulated wall with the ties yielded a minimum factor of safety greater than one. Simulations of the walls subject to lateral loads caused by 100 mph winds (0.2 psi) and seismic events with a peak ground acceleration of 1 ''g'' (0.66 psi) yielded no failures with or without the ties. Simulations of wall displacement during the seismic scenarios showed that the wall with the ties resulted in a maximum displacement that was 20% less than the wall without the ties.

  9. 78 FR 57619 - Prestressed Concrete Steel Rail Tie Wire From Mexico, Thailand, and the People's Republic of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ... People's Republic of China, and Thailand: Initiation of Antidumping Duty Investigations, 78 FR 29325 (May... International Trade Administration Prestressed Concrete Steel Rail Tie Wire From Mexico, Thailand, and the... antidumping duty investigations of imports of prestressed concrete steel rail tie wire from Mexico,...

  10. What’s Causing Toxicity in Sediments? Results of Twenty Years of Toxicity Identification and Evaluations (TIEs)

    EPA Science Inventory

    Sediment Toxicity Identification and Evaluation (TIEs) methods have been used for twenty years to identify the causes of toxicity in sediments around the world. We summarized and categorized results of more than 80 peer-reviewed TIE studies into non-ionic organic, cationic, ammo...

  11. Understanding Ebola Virus Transmission

    PubMed Central

    Judson, Seth; Prescott, Joseph; Munster, Vincent

    2015-01-01

    An unprecedented number of Ebola virus infections among healthcare workers and patients have raised questions about our understanding of Ebola virus transmission. Here, we explore different routes of Ebola virus transmission between people, summarizing the known epidemiological and experimental data. From this data, we expose important gaps in Ebola virus research pertinent to outbreak situations. We further propose experiments and methods of data collection that will enable scientists to fill these voids in our knowledge about the transmission of Ebola virus. PMID:25654239

  12. Series Transmission Line Transformer

    DOEpatents

    Buckles, Robert A. (Livermore, CA); Booth, Rex (Livermore, CA); Yen, Boris T. (El Cerrito, CA)

    2004-06-29

    A series transmission line transformer is set forth which includes two or more of impedance matched sets of at least two transmissions lines such as shielded cables, connected in parallel at one end ans series at the other in a cascading fashion. The cables are wound about a magnetic core. The series transmission line transformer (STLT) which can provide for higher impedance ratios and bandwidths, which is scalable, and which is of simpler design and construction.

  13. Development and Testing of a Prototype Grid-Tied Photovoltaic Power System

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2009-01-01

    The NASA Glenn Research Center (GRC) has developed and tested a prototype 2 kW DC grid-tied photovoltaic (PV) power system at the Center. The PV system has generated in excess of 6700 kWh since operation commenced in July 2006. The PV system is providing power to the GRC grid for use by all. Operation of the prototype PV system has been completely trouble free. A grid-tied PV power system is connected directly to the utility distribution grid. Facility power can be obtained from the utility system as normal. The PV system is synchronized with the utility system to provide power for the facility, and excess power is provided to the utility. The project transfers space technology to terrestrial use via nontraditional partners. GRC personnel glean valuable experience with PV power systems that are directly applicable to various space power systems, and provide valuable space program test data. PV power systems help to reduce harmful emissions and reduce the Nation s dependence on fossil fuels. Power generated by the PV system reduces the GRC utility demand, and the surplus power aids the community. Present global energy concerns reinforce the need for the development of alternative energy systems. Modern PV panels are readily available, reliable, efficient, and economical with a life expectancy of at least 25 years. Modern electronics has been the enabling technology behind grid-tied power systems, making them safe, reliable, efficient, and economical with a life expectancy of at least 25 years. Based upon the success of the prototype PV system, additional PV power system expansion at GRC is under consideration. The prototype grid-tied PV power system was successfully designed and developed which served to validate the basic principles described, and the theoretical work that was performed. The report concludes that grid-tied photovoltaic power systems are reliable, maintenance free, long life power systems, and are of significant value to NASA and the community.

  14. Tie2+ Bone Marrow Endothelial Cells Regulate Hematopoietic Stem Cell Regeneration Following Radiation Injury

    PubMed Central

    Doan, Phuong L.; Russell, J. Lauren; Himburg, Heather A.; Helms, Katherine; Harris, Jeffrey; Lucas, Joseph; Holshausen, Kirsten; Meadows, Sarah K.; Daher, Pamela; Jeffords, Laura B.; Chao, Nelson J.; Kirsch, David G.; Chute, John P.

    2013-01-01

    Hematopoietic stem cells (HSCs) reside in proximity to bone marrow endothelial cells (BM ECs) and maintenance of the HSC pool is dependent upon EC-mediated c-kit signaling. Here, we utilized genetic models to determine if radioprotection of BM ECs could facilitate hematopoietic regeneration following radiation-induced myelosuppression. We developed mice bearing deletion of the pro-apoptotic proteins, BAK and BAX, in Tie2+ endothelial cells (ECs) and HSCs (Tie2Bak/BaxFl/? mice) and compared their hematopoietic recovery following total body irradiation (TBI) with mice which retained Bax in Tie2+ cells. Mice bearing deletion of Bak and Bax in Tie2+ cells demonstrated protection of BM HSCs, preserved BM vasculature and 100% survival following lethal dose TBI. In contrast, mice that retained Bax expression in Tie2+ cells demonstrated depletion of BM HSCs, disrupted BM vasculature and 10% survival post-TBI. In a complementary study, VEcadherinBak/BaxFl/? mice, which lack Bak and Bax in VEcadherin+ ECs, also demonstrated increased recovery of BM stem/progenitor cells following TBI compared to mice which retained Bax in VEcadherin+ ECs. Importantly, chimeric mice which lacked Bak and Bax in HSCs but retained Bak and Bax in BM ECs displayed significantly decreased HSC content and survival following TBI compared to mice lacking Bak and Bax in both HSCs and BM ECs. These data suggest that the hematopoietic response to ionizing radiation is dependent upon HSC-autonomous responses but is regulated by BM EC-mediated mechanisms. Therefore, BM ECs may be therapeutically targeted as a means to augment hematopoietic reconstitution following myelosuppression. PMID:23132593

  15. Patterns of transmission investment

    E-print Network

    Joskow, Paul L.

    2005-01-01

    This paper examines a number of issues associated with alternative analytical approaches for evaluating investments in electricity transmission infrastructure and alternative institutional arrangements to govern network ...

  16. Transmission Line Security Monitor

    ScienceCinema

    None

    2013-05-28

    The Transmission Line Security Monitor is a multi-sensor monitor that mounts directly on high-voltage transmission lines to detect, characterize and communicate terrorist activity, human tampering and threatening conditions around support towers. For more information about INL's critical infrastructure protection research, visit http://www.facebook.com/idahonationallaboratory.

  17. Traction-drive transmission

    SciTech Connect

    Lindsley, E.F.

    1980-03-01

    A discussion is given of the Vadetec traction-drive transmission. It is claimed that when this traction-drive transmission is combined with an inertial drive line (energy storage system) and microprocessor control, fuel economy can be improved by 30 to 50 percent. (SC)

  18. Transmission Line Security Monitor

    SciTech Connect

    2011-01-01

    The Transmission Line Security Monitor is a multi-sensor monitor that mounts directly on high-voltage transmission lines to detect, characterize and communicate terrorist activity, human tampering and threatening conditions around support towers. For more information about INL's critical infrastructure protection research, visit http://www.facebook.com/idahonationallaboratory.

  19. Automatic transmission control method

    SciTech Connect

    Hasegawa, H.; Ishiguro, T.

    1989-07-04

    This patent describes a method of controlling an automatic transmission of an automotive vehicle. The transmission has a gear train which includes a brake for establishing a first lowest speed of the transmission, the brake acting directly on a ring gear which meshes with a pinion, the pinion meshing with a sun gear in a planetary gear train, the ring gear connected with an output member, the sun gear being engageable and disengageable with an input member of the transmission by means of a clutch. The method comprises the steps of: detecting that a shift position of the automatic transmission has been shifted to a neutral range; thereafter introducing hydraulic pressure to the brake if present vehicle velocity is below a predetermined value, whereby the brake is engaged to establish the first lowest speed; and exhausting hydraulic pressure from the brake if present vehicle velocity is higher than a predetermined value, whereby the brake is disengaged.

  20. Global TIE Observatories: Real Time Observational Astronomy Through a Robotic Telescope Network

    NASA Astrophysics Data System (ADS)

    Clark, G.; Mayo, L. A.

    2001-12-01

    Astronomy in grades K-12 is traditionally taught (if at all) using textbooks and a few simple hands-on activities. Teachers are generally not trained in observational astronomy techniques and are unfamiliar with the most basic astronomical concepts. In addition, most students, by High School graduation, will never have even looked through the eyepiece of a telescope. The problem becomes even more challenging in inner cities, remote rural areas and low socioeconomic communities where educational emphasis on topics in astronomy as well as access to observing facilities is limited or non existent. Access to most optical telescope facilities is limited to monthly observing nights that cater to a small percentage of the general public living near the observatory. Even here, the observing experience is a one-time event detached from the process of scientific enquiry and sustained educational application. Additionally, a number of large, "research grade" observatory facilities are largely unused, partially due to the slow creep of light pollution around the facilities as well as the development of newer, more capable telescopes. Though cutting edge science is often no longer possible at these sights, real research opportunities in astronomy remain numerous for these facilities as educational tools. The possibility now exists to establish a network of research grade telescopes, no longer useful to the professional astronomical community, that can be made accessible through classrooms, after school, and community based programs all across the country through existing IT technologies and applications. These telescopes could provide unparalleled research and educational opportunities for a broad spectrum of students and turns underutilized observatory facilities into valuable, state-of-the-art teaching centers. The NASA sponsored Telescopes In Education project has been wildly successful in engaging the K-12 education community in real-time, hands-on, interactive astronomy activities. Hundreds of schools in the US, Australia, Canada, England, and Japan have participated in the TIE program, remotely controlling the 24-inch telescope at the Mount Wilson Observatory from their classrooms. In recent years, several (approximately 20 to date) other telescopes have been, or are in the process of being, outfitted for remote use as TIE affiliates. Global TIE integrates these telescopes seamlessly into one virtual observatory and provides the services required to operate this facility, including a scheduling service, tools for data manipulation, an online proposal review environment, an online "Virtual TIE Student Ap J" for publication of results, and access to related educational materials provided by the TIE community. This presentation describes the Global TIE Observatory data and organizational systems and details the technology, partnerships, operational capabilities, science applications, and learning opportunities that this powerful virtual observatory network will provide.

  1. Local effects of redundant terrestrial and GPS-based tie vectors in ITRF-like combinations

    NASA Astrophysics Data System (ADS)

    Abbondanza, Claudio; Altamimi, Zuheir; Sarti, Pierguido; Negusini, Monia; Vittuari, Luca

    2009-11-01

    Tie vectors (TVs) between co-located space geodetic instruments are essential for combining terrestrial reference frames (TRFs) realised using different techniques. They provide relative positioning between instrumental reference points (RPs) which are part of a global geodetic network such as the international terrestrial reference frame (ITRF). This paper gathers the set of very long baseline interferometry (VLBI)-global positioning system (GPS) local ties performed at the observatory of Medicina (Northern Italy) during the years 2001-2006 and discusses some important aspects related to the usage of co-location ties in the combinations of TRFs. Two measurement approaches of local survey are considered here: a GPS-based approach and a classical approach based on terrestrial observations (i.e. angles, distances and height differences). The behaviour of terrestrial local ties, which routinely join combinations of space geodetic solutions, is compared to that of GPS-based local ties. In particular, we have performed and analysed different combinations of satellite laser ranging (SLR), VLBI and GPS long term solutions in order to (i) evaluate the local effects of the insertion of the series of TVs computed at Medicina, (ii) investigate the consistency of GPS-based TVs with respect to space geodetic solutions, (iii) discuss the effects of an imprecise alignment of TVs from a local to a global reference frame. Results of ITRF-like combinations show that terrestrial TVs originate the smallest residuals in all the three components. In most cases, GPS-based TVs fit space geodetic solutions very well, especially in the horizontal components (N, E). On the contrary, the estimation of the VLBI RP Up component through GPS technique appears to be awkward, since the corresponding post fit residuals are considerably larger. Besides, combination tests including multi-temporal TVs display local effects of residual redistribution, when compared to those solutions where Medicina TVs are added one at a time. Finally, the combination of TRFs turns out to be sensitive to the orientation of the local tie into the global frame.

  2. Tractor Transmissions. A Teaching Reference.

    ERIC Educational Resources Information Center

    American Association for Agricultural Engineering and Vocational Agriculture, Athens, GA.

    The manual was developed as a reference for teaching students about transmissions in farm tractors. The manual is divided into five sections: (1) transmission history, (2) gears and bearings in transmission, (3) sliding-gear transmissions, (4) planetary gearing, and (5) glossary. The working principles of the sliding-gear transmission, the most…

  3. Use of marine TIE methods in determining causes of toxicity to fish in a public marine aquarium

    SciTech Connect

    Ho, K.T.; Kuhn, A.; Burgess, R.M.; Pelletier, M.; Charles, J.

    1995-12-31

    Aquarium personnel observed that a number of organisms in the coral reef tank were succumbing to fungal and other diseases. It was suspected that organisms were compromised due to a common environmental stressor because many types of fish were affected. One possible stressor was the home-made painted coral decor in the tank. The coral reef decor was crumbling in several sections of the display and release of toxic agents was suspected. A water sample containing broken pieces of the decor was shipped to the lab and a TIE performed. Phase 1 TIE results indicated that toxicity to Mysidopsis bahia (mysid shrimp) was removed after EDTA addition and to some extent after cation exchange column treatment.None of the other TIE manipulations affected toxicity. Metal analyses indicated high concentrations of Zn, Cu, Ni, and Cd. To rule out the possibility of pathogens, irradiation was conducted as a novel TIE method. Results of further identification and confirmation methods using differing cation exchange column treatment. None of the other TIE manipulations affected toxicity. Metal analyses indicated high concentrations of Zn, Cu, Ni, and Cd. To rule out the possibility of pathogens, irradiation was conducted as a novel TIE method. Results of further identification and confirmation methods using differing cation exchange columns will be presented. This study demonstrates a unique application of TIE methods.

  4. Impact of Cross-Tie Properties on the Modal Behavior of Cable Networks on Cable-Stayed Bridges

    PubMed Central

    Ahmad, Javaid; Cheng, Shaohong; Ghrib, Faouzi

    2015-01-01

    Dynamic behaviour of cable networks is highly dependent on the installation location, stiffness, and damping of cross-ties. Thus, these are the important design parameters for a cable network. While the effects of the former two on the network response have been investigated to some extent in the past, the impact of cross-tie damping has rarely been addressed. To comprehend our knowledge of mechanics associated with cable networks, in the current study, an analytical model of a cable network will be proposed by taking into account both cross-tie stiffness and damping. In addition, the damping property of main cables in the network will also be considered in the formulation. This would allow exploring not only the effectiveness of a cross-tie design on enhancing the in-plane stiffness of a constituted cable network, but also its energy dissipation capacity. The proposed analytical model will be applied to networks with different configurations. The influence of cross-tie stiffness and damping on the modal response of various types of networks will be investigated by using the corresponding undamped rigid cross-tie network as a reference base. Results will provide valuable information on the selection of cross-tie properties to achieve more effective cable vibration control. PMID:26167539

  5. Rural-to-urban migrant adolescents in Guangzhou, China: psychological health, victimization, and local and trans-local ties.

    PubMed

    Cheung, Nicole W T

    2013-09-01

    Despite the emerging literature on the health of rural-to-urban migrant children in China, few studies have addressed victimization stressors and stress-buffering mechanisms related to the social relationships that link migrants to their host cities (local ties) and home communities (trans-local ties). This study compared rural-to-urban migrant adolescents and urban native adolescents to examine the relationships between victimization, local and trans-local ties, and mental well-being that might be unique to migrants. Participants were 482 migrant students and 838 urban native students in the eighth grade in Guangzhou who completed a school-based survey in spring 2011. Victimization was associated with suboptimal psychological health in both the migrant and urban native samples. Social ties directly boosted psychological health in both samples, with the effects of trans-local and local ties proving equally important among migrant adolescents. While both local and trans-local ties moderated the effect of victimization on migrant adolescents, that moderation mattered less for urban native youth. These results highlight that a better understanding of victimization stress and how it is affected by the locality of social ties as a coping resource could help to protect the health of young migrants in urban China. PMID:23906129

  6. Native leaf-tying caterpillars influence host plant use by the invasive Asiatic oak weevil through ecosystem engineering.

    PubMed

    Baer, Christina S; Marquis, Robert J

    2014-06-01

    We tested the effect of leaf-tying caterpillars, native ecosystem engineers, on the abundance and host feeding of an invasive insect, the Asiatic oak weevil, Cyrtepistomus castaneus (Roelofs). Leaf quality was previously thought to be the sole factor determining host use by C. castaneus, but adult weevils congregate in leaf ties made by lepidopteran larvae (caterpillars). Adult weevil abundance was naturally higher on Quercus alba and Q. velutina compared to four other tree species tested (Acer rubrum, Carya ovata, Cornus florida, and Sassafras albidum). These differences were associated with more natural leaf ties on the two Quercus species. In the laboratory, weevils fed on all six species but again preferred Q. alba and Q. velutina. When artificial ties were added to all six tree species, controlling for differences in leaf-tie density, adult weevil density increased on all six tree species, damage increased on all species but A. rubrum, and host ranking changed based on both abundance and damage. We conclude that leaf ties increase the local abundance of C. castaneus adults and their feeding. Thus, these native leaf-tying caterpillars engender the success of an invasive species via structural modification of potential host plants, the first described example of this phenomenon. PMID:25039212

  7. Selection based on the size of the black tie of the great tit may be reversed in urban habitats.

    PubMed

    Senar, Juan Carlos; Conroy, Michael J; Quesada, Javier; Mateos-Gonzalez, Fernando

    2014-07-01

    A standard approach to model how selection shapes phenotypic traits is the analysis of capture-recapture data relating trait variation to survival. Divergent selection, however, has never been analyzed by the capture-recapture approach. Most reported examples of differences between urban and nonurban animals reflect behavioral plasticity rather than divergent selection. The aim of this paper was to use a capture-recapture approach to test the hypothesis that divergent selection can also drive local adaptation in urban habitats. We focused on the size of the black breast stripe (i.e., tie width) of the great tit (Parus major), a sexual ornament used in mate choice. Urban great tits display smaller tie sizes than forest birds. Because tie size is mostly genetically determined, it could potentially respond to selection. We analyzed capture/recapture data of male great tits in Barcelona city (N = 171) and in a nearby (7 km) forest (N = 324) from 1992 to 2008 using MARK. When modelling recapture rate, we found it to be strongly influenced by tie width, so that both for urban and forest habitats, birds with smaller ties were more trap-shy and more cautious than their larger tied counterparts. When modelling survival, we found that survival prospects in forest great tits increased the larger their tie width (i.e., directional positive selection), but the reverse was found for urban birds, with individuals displaying smaller ties showing higher survival (i.e., directional negative selection). As melanin-based tie size seems to be related to personality, and both are heritable, results may be explained by cautious personalities being favored in urban environments. More importantly, our results show that divergent selection can be an important mechanism in local adaptation to urban habitats and that capture-recapture is a powerful tool to test it. PMID:25077014

  8. Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway

    PubMed Central

    Reinardy, Jessica L.; Corey, Daniel M.; Golzio, Christelle; Mueller, Sarah B.; Katsanis, Nicholas; Kontos, Christopher D.

    2015-01-01

    The endothelial receptor tyrosine kinase (RTK) Tie1 was discovered over 20 years ago, yet its precise function and mode of action remain enigmatic. To shed light on Tie1’s role in endothelial cell biology, we investigated a potential threonine phosphorylation site within the juxtamembrane domain of Tie1. Expression of a non-phosphorylatable mutant of this site (T794A) in zebrafish (Danio rerio) significantly disrupted vascular development, resulting in fish with stunted and poorly branched intersomitic vessels. Similarly, T794A-expressing human umbilical vein endothelial cells formed significantly shorter tubes with fewer branches in three-dimensional Matrigel cultures. However, mutation of T794 did not alter Tie1 or Tie2 tyrosine phosphorylation or downstream signaling in any detectable way, suggesting that T794 phosphorylation may regulate a Tie1 function independent of its RTK properties. Although T794 is within a consensus Akt phosphorylation site, we were unable to identify a physiological activator of Akt that could induce T794 phosphorylation, suggesting that Akt is not the physiological Tie1-T794 kinase. However, the small GTPase Ras-related C3 botulinum toxin substrate 1 (Rac1), which is required for angiogenesis and capillary morphogenesis, was found to associate with phospho-T794 but not the non-phosphorylatable T794A mutant. Pharmacological activation of Rac1 induced downstream activation of p21-activated kinase (PAK1) and T794 phosphorylation in vitro, and inhibition of PAK1 abrogated T794 phosphorylation. Our results provide the first demonstration of a signaling pathway mediated by Tie1 in endothelial cells, and they suggest that a novel feedback loop involving Rac1/PAK1 mediated phosphorylation of Tie1 on T794 is required for proper angiogenesis. PMID:26436659

  9. CHILD WELFARE AGENCY TIES TO PROVIDERS AND SCHOOLS AND SUBSTANCE ABUSE TREATMENT USE BY ADOLESCENTS

    PubMed Central

    Wells, Rebecca; Chuang, Emmeline; Haynes, Lindsey E.; Lee, I-Heng; Bai, Yu

    2010-01-01

    Policy makers and advocates are increasingly encouraging child-serving organizations to work together. The current study examined how child welfare agency ties with substance abuse treatment providers and schools correlated with substance abuse treatment for adolescents receiving child protective services. A sample of adolescents with substance use risk was extracted from a national survey of families engaged with child welfare. Logistic regressions with adjustments for complex survey design used child welfare agency ties to substance abuse treatment providers and schools to predict treatment. As expected, adolescents were more likely to report treatment when child protective services and substance abuse treatment were in the same agency and when child welfare agency directors reported joint planning with schools. However, child welfare agency agreements with substance abuse treatment providers were negatively associated with treatment. This unexpected finding implies that agencies may sometimes cooperate to address problems as well as to improve service utilization. PMID:20870374

  10. Employing static excitation control and tie line reactance to stabilize wind turbine generators

    NASA Technical Reports Server (NTRS)

    Hwang, H. H.; Mozeico, H. V.; Guo, T.

    1978-01-01

    An analytical representation of a wind turbine generator is presented which employs blade pitch angle feedback control. A mathematical model was formulated. With the functioning MOD-0 wind turbine serving as a practical case study, results of computer simulations of the model as applied to the problem of dynamic stability at rated load are also presented. The effect of the tower shadow was included in the input to the system. Different configurations of the drive train, and optimal values of the tie line reactance were used in the simulations. Computer results revealed that a static excitation control system coupled with optimal values of the tie line reactance would effectively reduce oscillations of the power output, without the use of a slip clutch.

  11. Utility-scale grid-tied PV inverter reliability workshop summary report.

    SciTech Connect

    Granata, Jennifer E.; Quintana, Michael A.; Tasca, Coryne Adelle; Atcitty, Stanley

    2011-07-01

    A key to the long-term success of the photovoltaic (PV) industry is confidence in the reliability of PV systems. Inverters are the most commonly noted cause of PV system incidents triggered in the field. While not all of these incidents are reliability-related or even necessarily failures, they still result in a loss of generated power. With support from the U.S. Department of Energy's Solar Energy Technologies Program, Sandia National Laboratories organized a Utility-Scale Grid-Tied Inverter Reliability Workshop in Albuquerque, New Mexico, January 27-28, 2011. The workshop addressed the reliability of large (100-kilowatt+) grid-tied inverters and the implications when such inverters fail, evaluated inverter codes and standards, and provided discussion about opportunities to enhance inverter reliability. This report summarizes discussions and presentations from the workshop and identifies opportunities for future efforts.

  12. Silicon-on-insulator field effect transistor with improved body ties for rad-hard applications

    DOEpatents

    Schwank, James R. (Albuquerque, NM); Shaneyfelt, Marty R. (Albuquerque, NM); Draper, Bruce L. (Albuquerque, NM); Dodd, Paul E. (Tijeras, NM)

    2001-01-01

    A silicon-on-insulator (SOI) field-effect transistor (FET) and a method for making the same are disclosed. The SOI FET is characterized by a source which extends only partially (e.g. about half-way) through the active layer wherein the transistor is formed. Additionally, a minimal-area body tie contact is provided with a short-circuit electrical connection to the source for reducing floating body effects. The body tie contact improves the electrical characteristics of the transistor and also provides an improved single-event-upset (SEU) radiation hardness of the device for terrestrial and space applications. The SOI FET also provides an improvement in total-dose radiation hardness as compared to conventional SOI transistors fabricated without a specially prepared hardened buried oxide layer. Complementary n-channel and p-channel SOI FETs can be fabricated according to the present invention to form integrated circuits (ICs) for commercial and military applications.

  13. Dendrometer bands made easy: using modified cable ties to measure incremental growth of trees

    USGS Publications Warehouse

    Anemaet, Evelyn R.; Middleton, Beth A.

    2013-01-01

    Dendrometer bands are a useful way to make sequential repeated measurements of tree growth, but traditional dendrometer bands can be expensive, time consuming, and difficult to construct in the field. An alternative to the traditional method of band construction is to adapt commercially available materials. This paper describes how to construct and install dendrometer bands using smooth-edged, stainless steel, cable tie banding and attachable rollerball heads. As a performance comparison, both traditional and cable tie dendrometer bands were installed on baldcypress trees at the National Wetlands Research Center in Lafayette, Louisiana, by both an experienced and a novice worker. Band installation times were recorded, and growth of the trees as estimated by the two band types was measured after approximately one year, demonstrating equivalence of the two methods. This efficient approach to dendrometer band construction can help advance the knowledge of long-term tree growth in ecological studies.

  14. Skin closure after arthroscopy utilizing a pull-out bow-tie subcuticular suture

    PubMed Central

    Nacius, Lori Ann; Pascual-Garrido, Cecilia; Sagiv, Paul; Mei-Dan, Omer

    2014-01-01

    Summary Background: suturing techniques employed to close subcuticular surgical incisions are varied. Purpose: we present the “bow-tie” stitch, which is removed by pulling one side of the stitch with no need for sharp object stitch cutting. The stitch results in good approximation and scarring while enabling proper oozing. Methods: we have used this suture repeatedly for wound closure after hip and knee arthroscopy; its application to other superficial skin closures is easily appreciated. Results: this method of skin closure allows for ease of tying for the surgeon, aesthetically pleasing results for the patient, pain-free suture removal, no risk of suture knots becoming embedded in healing tissue, and decreased risk of infection and damage to skin, as instruments are not required for suture removal. PMID:25767775

  15. GNSS-SLR satellite co-location for the estimate of local ties

    NASA Astrophysics Data System (ADS)

    Bruni, Sara; Zerbini, Susanna; Errico, Maddalena; Santi, Efisio

    2013-04-01

    The current realization of the International Terrestrial Reference Frame (ITRF) is based on four different space-geodetic techniques, so that the benefits brought by each observing system to the definition of the frame can compensate for the drawbacks of the others and technique-specific systematic errors might be identified. The strategy used to combine the observations from the different techniques is then of prominent importance for the realization of a precise and stable reference frame. This study concentrates, in particular, on the combination of Satellite Laser Ranging (SLR) and Global Navigation Satellite System (GNSS) observations by exploiting satellite co-locations. This innovative approach is based on the fact that laser tracking of GNSS satellites, carrying on board laser reflector arrays, allows for the combination of optical and microwave signals in the determination of the spacecraft orbit. Besides, the use of satellite co-locations differs quite significantly from the traditional combination method in which each single technique solution is carried out autonomously and is interrelated in a second step. One of the benefits of the approach adopted in this study is that it allows for an independent validation of the local tie, i.e. of the vector connecting the SLR and GNSS reference points in a multi-techniques station. Typically, local ties are expressed by a single value, measured with ground-based geodetic techniques and taken as constant. In principle, however, local ties might show time variations likely caused by the different monumentation characteristics of the GNSS antennas with respect to those of a SLR system. This study evaluates the possibility of using the satellite co-location approach to generate local-ties time series by means of observations available for a selected network of ILRS stations. The data analyzed in this study were acquired as part of the NASA's Earth Science Data Systems and are archived and distributed by the Crustal Dynamics Data Information System (CDDIS).

  16. Tie-mediated signal from apoptotic cells protects stem cells in Drosophila melanogaster

    PubMed Central

    Xing, Yalan; Su, Tin Tin; Ruohola-Baker, Hannele

    2015-01-01

    Many types of normal and cancer stem cells are resistant to killing by genotoxins, but the mechanism for this resistance is poorly understood. Here we show that adult stem cells in Drosophila melanogaster germline and midgut are resistant to ionizing radiation (IR) or chemically induced apoptosis and dissect the mechanism for this protection. We find that upon IR the receptor tyrosine kinase Tie/Tie-2 is activated, leading to the upregulation of microRNA bantam that represses FOXO-mediated transcription of pro-apoptotic Smac/DIA-BLO orthologue, Hid in germline stem cells. Knockdown of the IR-induced putative Tie ligand, Pvf1, a functional homologue of human Angiopoietin, in differentiating daughter cells renders germline stem cells sensitive to IR, suggesting that the dying daughters send a survival signal to protect their stem cells for future repopulation of the tissue. If conserved in cancer stem cells, this mechanism may provide therapeutic options for the eradication of cancer. PMID:25959206

  17. Plasma Fibronectin Promotes Tumor Cell Survival and Invasion through Regulation of Tie2

    PubMed Central

    Knowles, Lynn M.; Malik, Gunjan; Pilch, Jan

    2013-01-01

    Our previous research has shown that plasma fibronectin promotes lung metastasis by facilitating tumor cell invasion in clotted plasma. To evaluate the role of clotted plasma for tumor cell survival, we treated B16F1 cells embedded in a 3-dimensional matrix of fibrin with tumor necrosis factor ? (TNF?), a cytokine with anti-tumor activity. Under these conditions, TNF? caused significant cytotoxicity, which was prevented when we added plasma fibronectin to the fibrin clot. Fibronectin-mediated TNF? resistance was dependent on PI3-kinase, which also mediated the pro-adhesive and pro-invasive effects of plasma fibronectin on tumor cells. To further investigate the role of plasma fibronectin in tumor cell signaling, we performed a gene array that showed specific upregulation of Tie2 in B16F1 cells embedded in fibrin-fibronectin compared to fibrin. Importantly, inhibition of Tie2 resulted in decreased tumor cell invasion, reduced colony formation and increased tumor cell death in response to TNF?. Together, our findings indicate that plasma fibronectin induces tumor cell invasion and protects tumor cells from the cytotoxic effects of inflammatory mediators through up-regulation of Tie2. PMID:23833683

  18. Finite element analyses of continuous filament ties for masonry applications : final report for the Arquin Corporation.

    SciTech Connect

    Quinones, Armando, Sr.; Bibeau, Tiffany A.; Ho, Clifford Kuofei

    2008-08-01

    Finite-element analyses were performed to simulate the response of a hypothetical vertical masonry wall subject to different lateral loads with and without continuous horizontal filament ties laid between rows of concrete blocks. A static loading analysis and cost comparison were also performed to evaluate optimal materials and designs for the spacers affixed to the filaments. Results showed that polypropylene, ABS, and polyethylene (high density) were suitable materials for the spacers based on performance and cost, and the short T-spacer design was optimal based on its performance and functionality. Simulations of vertical walls subject to static loads representing 100 mph winds (0.2 psi) and a seismic event (0.66 psi) showed that the simulated walls performed similarly and adequately when subject to these loads with and without the ties. Additional simulations and tests are required to assess the performance of actual walls with and without the ties under greater loads and more realistic conditions (e.g., cracks, non-linear response).

  19. The Tie2-agonist Vasculotide rescues mice from influenza virus infection

    PubMed Central

    Sugiyama, Michael G.; Armstrong, Susan M.; Wang, Changsen; Hwang, David; Leong-Poi, Howard; Advani, Andrew; Advani, Suzanne; Zhang, Haibo; Szaszi, Katalin; Tabuchi, Arata; Kuebler, Wolfgang M.; Van Slyke, Paul; Dumont, Dan J.; Lee, Warren L.

    2015-01-01

    Seasonal influenza virus infections cause hundreds of thousands of deaths annually while viral mutation raises the threat of a novel pandemic strain. Antiviral drugs exhibit limited efficacy unless administered early and may induce viral resistance. Thus, targeting the host response directly has been proposed as a novel therapeutic strategy with the added potential benefit of not eliciting viral resistance. Severe influenza virus infections are complicated by respiratory failure due to the development of lung microvascular leak and acute lung injury. We hypothesized that enhancing lung endothelial barrier integrity could improve the outcome. Here we demonstrate that the Tie2-agonist tetrameric peptide Vasculotide improves survival in murine models of severe influenza, even if administered as late as 72?hours after infection; the benefit was observed using three strains of the virus and two strains of mice. The effect required Tie2, was independent of viral replication and did not impair lung neutrophil recruitment. Administration of the drug decreased lung edema, arterial hypoxemia and lung endothelial apoptosis; importantly, Vasculotide is inexpensive to produce, is chemically stable and is unrelated to any Tie2 ligands. Thus, Vasculotide may represent a novel and practical therapy for severe infections with influenza. PMID:26046800

  20. Comparison of Two-Fluid and Kinetic Simulations of Magnetic Reconnection in Line-Tied Systems

    NASA Astrophysics Data System (ADS)

    Akcay, C.; Daughton, W. S.; Stanier, A.; Lukin, V. S.

    2014-12-01

    The evolution of plasmas in magnetically dominated low-? regimes often leads to the formation of nearly force-free current sheets where magnetic reconnection may be triggered by the tearing instability. In three-dimensional systems, the tearing of a current sheet and ensuing magnetic reconnection can result in the formation and interaction of magnetic flux ropes. In addition, many space and laboratory plasmas feature current sheets of finite extent that are embedded in larger systems with line-tied field boundary conditions. Motivated by these properties, we examine the influence of line-tied boundary conditions on the onset and development of three-dimensional magnetic reconnection in kinetic-scale force-free layers. To better understand the physics, we perform cross-comparisons between fully kinetic VPIC simulations and two-fluid HiFi simulations. We focus on a range of guide fields Bg=(1-10)B0 relevant to both space and laboratory plasmas, and compare the evolution between systems with line-tied and periodic boundary conditions.

  1. Social features of online networks: the strength of intermediary ties in online social media.

    PubMed

    Grabowicz, Przemyslaw A; Ramasco, José J; Moro, Esteban; Pujol, Josep M; Eguiluz, Victor M

    2012-01-01

    An increasing fraction of today's social interactions occur using online social media as communication channels. Recent worldwide events, such as social movements in Spain or revolts in the Middle East, highlight their capacity to boost people's coordination. Online networks display in general a rich internal structure where users can choose among different types and intensity of interactions. Despite this, there are still open questions regarding the social value of online interactions. For example, the existence of users with millions of online friends sheds doubts on the relevance of these relations. In this work, we focus on Twitter, one of the most popular online social networks, and find that the network formed by the basic type of connections is organized in groups. The activity of the users conforms to the landscape determined by such groups. Furthermore, Twitter's distinction between different types of interactions allows us to establish a parallelism between online and offline social networks: personal interactions are more likely to occur on internal links to the groups (the weakness of strong ties); events transmitting new information go preferentially through links connecting different groups (the strength of weak ties) or even more through links connecting to users belonging to several groups that act as brokers (the strength of intermediary ties). PMID:22247773

  2. Stories of Change: TieVie - The Support Service for Finnish Universities Toward the Information Society

    NASA Astrophysics Data System (ADS)

    Kairamo, Anna-Kaarina; Sinko, Matti

    In this article, the authors discuss and evaluate the TieVie capacity building project for Finnish universities in a larger historical context of strategic developments in the use of information and communications technology (ICT) in learning. The TieVie project was a support service project for the Finnish Virtual University (FVU) which offered training in the educational use of ICT to the staff of Finnish universities in 2001-2008. It was financed by the Ministry of Education as part of the Virtual University project funding till the end of 2006. During 2007-2008, the program was fee-funded. The project was designed and implemented by the educational development support service units of five universities: Universities of Oulu, Turku, Jyväskylä, and Helsinki, and Helsinki University of Technology. The TieVie project was launched on the basis of the need to strengthen the e-Learning skills and expertise among Finnish university staff. This need was recognized in the national strategy for education, training, and research in the information society outlined by the Ministry of Education in 2000.

  3. Fast-shock formation in line-tied magnetic reconnection models of solar flares

    NASA Technical Reports Server (NTRS)

    Forbes, T. G.

    1986-01-01

    In a previous study by the author, an approximately stationary fast shock was tentatively identified in a numerical experiment designed to study line-tied magnetic reconnection. Here the evidence for the occurrence of a stationary fast shock is reexamined, and the previous identification is confirmed. In the numerical experiment, line-tied reconnection is modeled by a configuration which produces two supermagnetosonic outflow jets - one directed upward, away from the photosphere, and one directed downward, toward an arcade of closed magnetic loops tied to the photosphere. The fast shock occurs when the downward-directed jet encounters the obstacle formed by the closed loops. Although the existence of a stationary, or nearly stationary, fast shock is confirmed, the transition from the supermagnetosonic flow region upstream of the shock to the nearly static region downstream of the shock is more complicated than was previously thought. Immediately downstream of the shock, there exists a deflection sheath in which the submagnetosonic flow coming out of the shock is diverted around the region of static closed loops. The MHD jump conditions are used to investigate the characteristics of the fast shock and to show that a stationary shock cannot exist unless accompanied by a deflection sheath. Analysis of the shock's location and dimensions suggests that such fast shocks may contribute to particle acceleration and to thermal condensation in flares.

  4. Onset and Evolution of Magnetic Reconnection in Line-Tied Systems

    NASA Astrophysics Data System (ADS)

    Daughton, W. S.; Akcay, C.; Billey, Z.; Finn, J.; Zweibel, E.; Gekelman, W. N.

    2014-12-01

    In space and astrophysical plasmas, current sheets arise spontaneously from the interaction of large-scale flows or magnetic structures. As these current layers approach kinetic scales, they may become unstable to the collisionless tearing instability, resulting in the formation and interaction of magnetic flux ropes. While theoretical treatments of the tearing instability have largely focused on 1D equilibria with periodic boundary conditions, current sheets in nature have a finite spatial extent and are embedded within larger open systems. In many applications, the field boundary conditions are line-tied as in the case of flux ropes on the dayside magnetopause where the ionosphere acts as a conducting surface. To assess the applicability of existing tearing theory to these more realistic configurations, we consider a series of 3D kinetic simulations of initially force-free current layers with line-tied boundary conditions for the fields, and open boundaries for the particles. The geometry and plasma parameters are motivated by a new laboratory experiment on the Large Plasma Device at UCLA. For sufficiently long systems, we demonstrate that key aspects of the theory remain valid, and a threshold condition is derived for the onset of reconnection in line-tied systems. To gain additional insight into the nonlinear evolution, field-line mapping diagnostics are employed to characterize the 3D structure of the magnetic field, the nonlinear reconnection rate and the dominant non-ideal terms in the generalized Ohm's law.

  5. The development of a tongue assessment tool to assist with tongue-tie identification

    PubMed Central

    Ingram, Jenny; Johnson, Debbie; Copeland, Marion; Churchill, Cathy; Taylor, Hazel; Emond, Alan

    2015-01-01

    Aim To produce a simple tool with good transferability to provide a consistent assessment of tongue appearance and function in infants with tongue-tie. Methods The Bristol Tongue Assessment Tool (BTAT) was developed based on clinical practice and with reference to the Hazelbaker Assessment Tool for Lingual Frenulum Function (ATLFF). This paper documents 224 tongue assessments using the BTAT. There were 126 tongue assessments recorded using the BTAT and ATLFF tools to facilitate comparisons between them. Paired BTAT assessments were obtained from eight midwives who were using the new assessment tool. Results There was acceptable internal reliability for the four-item BTAT (Cronbach's ?=0.708) and the eight midwives who used it showed good correlation in the consistency of its use (ICC=0.760). The BTAT showed a strong and significant correlation (0.89) with the ATLFF, indicating that the simpler BTAT could be used in place of the more detailed assessment tool to score the extent of a tongue-tie. Midwives found it quick and easy to use and felt that it would be easy to teach to others. Conclusions The BTAT provides an objective, clear and simple measure of the severity of a tongue-tie, to inform selection of infants for frenotomy and to monitor the effect of the procedure. PMID:25877288

  6. Hybrid geared traction transmissions

    NASA Technical Reports Server (NTRS)

    Nasvytis, A. L.; White, G.

    1983-01-01

    The basic configuration of geared traction drives, geometric and structural factors to be considered in their construction, and current work on hybrid helicopter transmissions rated at 500 and 3000 hp are discussed.

  7. Transmission of Mumps

    MedlinePLUS

    ... IgM Serology Publications and Resources MMWR Articles Outbreak Articles Related Links World Health Organization Medline Plus Transmission of Mumps Language: English Español (Spanish) Recommend on Facebook Tweet Share Compartir ...

  8. Transmission of bilharziasis

    PubMed Central

    Webbe, G.

    1965-01-01

    Accurate quantitative assessment is essential to any study of disease transmission; in relation to the transmission of bilharziasis the most important characteristics that have to be determined include density, reproduction and mortality rates, the age and sex structure of the population, dispersion and the intrinsic rate of natural increase (the biotic potential). The author discusses techniques that have been developed to yield this and other information and stresses the need to evaluate such techniques objectively. Some basic principles of population ecology are defined and discussed in relation to the control of transmission. It is considered that laboratory studies can be usefully carried on in conjunction with field work but that they cannot be substituted for field investigations in determining the parameters of bilharziasis transmission for a given area. PMID:5294586

  9. Down hole transmission system

    DOEpatents

    Hall, David R. (Provo, UT); Hall, Jr., H. Tracy (Provo, UT)

    2007-07-24

    A transmission system in a downhole component comprises a data transmission element in both ends of the downhole component. Each data transmission element houses an electrically conducting coil in a MCEI circular trough. The electrically conducting coil comprises at least two generally fractional loops. In the preferred embodiment, the transmission elements are connected by an electrical conductor. Preferably, the electrical conductor is a coaxial cable. Preferably, the MCEI trough comprises ferrite. In the preferred embodiment, the fractional loops are connected by a connecting cable. In one aspect of the present invention, the connecting cable is a pair of twisted wires. In one embodiment the connecting cable is a shielded pair of twisted wires. In another aspect of the present invention, the connecting cable is a coaxial cable. The connecting cable may be disposed outside of the MCEI circular trough.

  10. Transmission of Flu (Influenza)

    MedlinePLUS

    ... Skip Content Marketing Share this: Main Content Area Flu (Influenza) Transmission How Flu Spreads Coughing and Sneezing People with flu can ... not be shared without washing thoroughly first. The Flu Is Contagious You may be able to pass ...

  11. Production and Transmission Measurement

    E-print Network

    Wilkinson, Gerald S.

    , interference, scattering, bioluminescence · Transmission through the environment · Optimal hue, contrast of color: bioluminescence Bioluminescence is common among marine organisms, especially deep-sea fishes. #12;Bioluminescence in squid · Created by symbiotic Vibrio bacteria · Used for counter- illumination to downwelling

  12. Design of a Glenn Research Center Solar Field Grid-Tied Photovoltaic Power System

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2009-01-01

    The NASA Glenn Research Center (GRC) designed, developed, and installed, a 37.5 kW DC photovoltaic (PV) Solar Field in the GRC West Area in the 1970s for the purpose of testing PV panels for various space and terrestrial applications. The PV panels are arranged to provide a nominal 120 VDC. The GRC Solar Field has been extremely successful in meeting its mission. The PV panels and the supporting electrical systems are all near their end of life. GRC has designed a 72 kW DC grid-tied PV power system to replace the existing GRC West Area Solar Field. The 72 kW DC grid-tied PV power system will provide DC solar power for GRC PV testing applications, and provide AC facility power for all times that research power is not required. A grid-tied system is connected directly to the utility distribution grid. Facility power can be obtained from the utility system as normal. The PV system is synchronized with the utility system to provide power for the facility, and excess power is provided to the utility for use by all. The project transfers space technology to terrestrial use via nontraditional partners. GRC personnel glean valuable experience with PV power systems that are directly applicable to various space power systems, and provide valuable space program test data. PV power systems help to reduce harmful emissions and reduce the Nation s dependence on fossil fuels. Power generated by the PV system reduces the GRC utility demand, and the surplus power aids the community. Present global energy concerns reinforce the need for the development of alternative energy systems. Modern PV panels are readily available, reliable, efficient, and economical with a life expectancy of at least 25 years. Modern electronics has been the enabling technology behind grid-tied power systems, making them safe, reliable, efficient, and economical with a life expectancy of at least 25 years. The report concludes that the GRC West Area grid-tied PV power system design is viable for a reliable, maintenance free, long life power system that is of significant value to NASA and the community.

  13. Development and Testing of the Glenn Research Center Visitor's Center Grid-Tied Photovoltaic Power System

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2009-01-01

    The NASA Glenn Research Center (GRC) has developed, installed, and tested a 12 kW DC grid-tied photovoltaic (PV) power system at the GRC Visitor s Center. This system utilizes a unique ballast type roof mount for installing the photovoltaic panels on the roof of the Visitor s Center with no alterations or penetrations to the roof. The PV system has generated in excess of 15000 kWh since operation commenced in August 2008. The PV system is providing power to the GRC grid for use by all. Operation of the GRC Visitor s Center PV system has been completely trouble free. A grid-tied PV power system is connected directly to the utility distribution grid. Facility power can be obtained from the utility system as normal. The PV system is synchronized with the utility system to provide power for the facility, and excess power is provided to the utility. The project transfers space technology to terrestrial use via nontraditional partners. GRC personnel glean valuable experience with PV power systems that are directly applicable to various space power systems, and provides valuable space program test data. PV power systems help to reduce harmful emissions and reduce the Nation s dependence on fossil fuels. Power generated by the PV system reduces the GRC utility demand, and the surplus power aids the community. Present global energy concerns reinforce the need for the development of alternative energy systems. Modern PV panels are readily available, reliable, efficient, and economical with a life expectancy of at least 25 years. Modern electronics has been the enabling technology behind grid-tied power systems, making them safe, reliable, efficient, and economical with a life expectancy of at least 25 years. Based upon the success of the GRC Visitor s Center PV system, additional PV power system expansion at GRC is under consideration. The GRC Visitor s Center grid-tied PV power system was successfully designed and developed which served to validate the basic principles described, and the theoretical work that was performed. The report concludes that grid-tied photovoltaic power systems are reliable, maintenance free, long life power systems, and are of significant value to NASA and the community.

  14. On inferring liquid-liquid phase boundaries and tie lines from ternary mixture light scattering.

    PubMed

    Wahle, Chris W; Ross, David S; Thurston, George M

    2012-07-21

    We investigate the possibility of using light scattering data in the single-phase regions of a ternary liquid mixture phase diagram to infer ternary mixture coexistence curves, and to infer tie lines joining the compositions of isotropic liquid phases in thermodynamic equilibrium. Previous analyses of a nonlinear light scattering partial differential equation (LSPDE) show that it provides for reconstruction of ternary [D. Ross, G. Thurston, and C. Lutzer, J. Chem. Phys. 129, 064106 (2008); C. Wahle, D. Ross, and G. Thurston, J. Chem. Phys. 137, 034201 (2012)] and quaternary [C. Wahle, D. Ross, and G. Thurston, J. Chem. Phys. 137, 034202 (2012)] mixing free energies from light scattering data, and that if the coexistence curves are already known, it can also yield ternary tie lines and triangles [D. Ross, G. Thurston, and C. Lutzer, J. Chem. Phys. 129, 064106 (2008)]. Here, we show that the LSPDE can be used more generally, to infer phase boundaries and tie lines from light scattering data in the single-phase region, without prior knowledge of the coexistence curve, if the single-phase region is connected. The method extends the fact that the reciprocal light scattering intensity approaches zero at the thermodynamic spinodal. Expressing the free energy as the sum of ideal and excess parts leads to a natural family of Pade? approximants for the reciprocal Rayleigh ratio. To test the method, we evaluate the single-phase reciprocal Rayleigh ratio resulting from the mean-field, regular solution model on a fine grid. We then use a low-order approximant to extrapolate the reciprocal Rayleigh ratio into metastable and unstable regions. In the metastable zone, the extrapolation estimates light scattering prior to nucleation and growth of a new phase. In the unstable zone, the extrapolation produces a negative function that in the present context is a computational convenience. The original and extrapolated reciprocal light scattering are jointly used as input to solving the LSPDE to deduce the mixing free energy and its convex hull. When projected onto the composition triangle, the boundary of the convexified part of the free energy is the phase boundary, and lines on the convexified region along which the second directional derivative is zero are the tie lines. We find that the tie lines and phase boundaries so deduced agree well with their exact values. This work is a step toward developing methods for inferring phase boundaries from real light scattering intensities measured with noise, from mixtures having compositions on a coarser grid. PMID:22830695

  15. Measurement of bow tie profiles in CT scanners using a real-time dosimeter

    PubMed Central

    Whiting, Bruce R.; Evans, Joshua D.; Dohatcu, Andreea C.; Williamson, Jeffrey F.; Politte, David G.

    2014-01-01

    Purpose: Several areas of computed tomography (CT) research require knowledge about the intensity profile of the x-ray fan beam that is introduced by a bow tie filter. This information is considered proprietary by CT manufacturers, so noninvasive measurement methods are required. One method using real-time dosimeters has been proposed in the literature. A commercially available dosimeter was used to apply that method, and analysis techniques were developed to extract fan beam profiles from measurements. Methods: A real-time ion chamber was placed near the periphery of an empty CT gantry and the dose rate versus time waveform was recorded as the x-ray source rotated about the isocenter. In contrast to previously proposed analysis methods that assumed a pointlike detector, the finite-size ion chamber received varying amounts of coverage by the collimated x-ray beam during rotation, precluding a simple relationship between the source intensity as a function of fan beam angle and measured intensity. A two-parameter model for measurement intensity was developed that included both effective collimation width and source-to-detector distance, which then was iteratively solved to minimize the error between duplicate measurements at corresponding fan beam angles, allowing determination of the fan beam profile from measured dose-rate waveforms. Measurements were performed on five different scanner systems while varying parameters such as collimation, kVp, and bow tie filters. On one system, direct measurements of the bow tie profile were collected for comparison with the real-time dosimeter technique. Results: The data analysis method for a finite-size detector was found to produce a fan beam profile estimate with a relative error between duplicate measurement intensities of <5%. It was robust over a wide range of collimation widths (e.g., 1–40 mm), producing fan beam profiles that agreed with a relative error of 1%–5%. Comparison with a direct measurement technique on one system produced agreement with a relative error of 2%–6%. Fan beam profiles were found to differ for different filter types on a given system and between different vendors. Conclusions: A commercially available real-time dosimeter probe was found to be a convenient and accurate instrument for measuring fan beam profiles. An analysis method was developed that could handle a wide range of collimation widths by explicitly considering the finite width of the ion chamber. Relative errors in the profiles were found to be less than 5%. Measurements of five different clinical scanners demonstrate the variation in bow tie designs, indicating that generic bow tie models will not be adequate for CT system research. PMID:25281967

  16. Measurement of bow tie profiles in CT scanners using a real-time dosimeter

    SciTech Connect

    Whiting, Bruce R.; Evans, Joshua D.; Williamson, Jeffrey F.; Dohatcu, Andreea C.; Politte, David G.

    2014-10-15

    Purpose: Several areas of computed tomography (CT) research require knowledge about the intensity profile of the x-ray fan beam that is introduced by a bow tie filter. This information is considered proprietary by CT manufacturers, so noninvasive measurement methods are required. One method using real-time dosimeters has been proposed in the literature. A commercially available dosimeter was used to apply that method, and analysis techniques were developed to extract fan beam profiles from measurements. Methods: A real-time ion chamber was placed near the periphery of an empty CT gantry and the dose rate versus time waveform was recorded as the x-ray source rotated about the isocenter. In contrast to previously proposed analysis methods that assumed a pointlike detector, the finite-size ion chamber received varying amounts of coverage by the collimated x-ray beam during rotation, precluding a simple relationship between the source intensity as a function of fan beam angle and measured intensity. A two-parameter model for measurement intensity was developed that included both effective collimation width and source-to-detector distance, which then was iteratively solved to minimize the error between duplicate measurements at corresponding fan beam angles, allowing determination of the fan beam profile from measured dose-rate waveforms. Measurements were performed on five different scanner systems while varying parameters such as collimation, kVp, and bow tie filters. On one system, direct measurements of the bow tie profile were collected for comparison with the real-time dosimeter technique. Results: The data analysis method for a finite-size detector was found to produce a fan beam profile estimate with a relative error between duplicate measurement intensities of <5%. It was robust over a wide range of collimation widths (e.g., 1–40 mm), producing fan beam profiles that agreed with a relative error of 1%–5%. Comparison with a direct measurement technique on one system produced agreement with a relative error of 2%–6%. Fan beam profiles were found to differ for different filter types on a given system and between different vendors. Conclusions: A commercially available real-time dosimeter probe was found to be a convenient and accurate instrument for measuring fan beam profiles. An analysis method was developed that could handle a wide range of collimation widths by explicitly considering the finite width of the ion chamber. Relative errors in the profiles were found to be less than 5%. Measurements of five different clinical scanners demonstrate the variation in bow tie designs, indicating that generic bow tie models will not be adequate for CT system research.

  17. Multistate differential transmission

    SciTech Connect

    Whalen, B.

    1987-09-01

    A multistate transmission is described having an input shaft and an output shaft comprising: a. planetary gear train means having a ring gear, planetary gears with planetary gear carrier, and a sun gear, the planetary gear train means connected to the output shaft; b. first bypass means connecting the input shaft to the planetary gear train means; c. differential transmission means for receiving its input from the input shaft and having means to adjust the torque and speed output infinitely variable over its range of operation for each state of the transmission; d. power return means for receiving the output of the differential transmission means; e. means including clutch operated speed reversing means for interconnecting the sun gear in the planetary gear train means with the power return means; f. the power return means including a first gear to receive the output of the differential transmission means; g. first multispeed transmission means connecting the means for supporting the carrier shaft to the first bypass means.

  18. National transmission grid study

    SciTech Connect

    Abraham, Spencer

    2003-05-31

    The National Energy Policy Plan directed the U.S. Department of Energy (DOE) to conduct a study to examine the benefits of establishing a national electricity transmission grid and to identify transmission bottlenecks and measures to address them. DOE began by conducting an independent analysis of U.S. electricity markets and identifying transmission system bottlenecks using DOE’s Policy Office Electricity Modeling System (POEMS). DOE’s analysis, presented in Section 2, confirms the central role of the nation’s transmission system in lowering costs to consumers through increased trade. More importantly, DOE’s analysis also confirms the results of previous studies, which show that transmission bottlenecks and related transmission system market practices are adding hundreds of millions of dollars to consumers’ electricity bills each year. A more detailed technical overview of the use of POEMS is provided in Appendix A. DOE led an extensive, open, public input process and heard a wide range of comments and recommendations that have all been considered.1 More than 150 participants registered for three public workshops held in Detroit, MI (September 24, 2001); Atlanta, GA (September 26, 2001); and Phoenix, AZ (September 28, 2001).

  19. 50 CFR 86.31 - How much money may I charge the public to use tie-up facilities?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...THE INTERIOR (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Public Use of the Facility § 86.31 How much money may I charge the public to use tie-up facilities?...

  20. 50 CFR 86.31 - How much money may I charge the public to use tie-up facilities?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...THE INTERIOR (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Public Use of the Facility § 86.31 How much money may I charge the public to use tie-up facilities?...

  1. 50 CFR 86.31 - How much money may I charge the public to use tie-up facilities?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...INTERIOR (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE AND SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Public Use of the Facility § 86.31 How much money may I charge the public to use tie-up facilities?...

  2. 50 CFR 86.31 - How much money may I charge the public to use tie-up facilities?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...INTERIOR (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE AND SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Public Use of the Facility § 86.31 How much money may I charge the public to use tie-up facilities?...

  3. 50 CFR 86.31 - How much money may I charge the public to use tie-up facilities?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...THE INTERIOR (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM BOATING INFRASTRUCTURE GRANT (BIG) PROGRAM Public Use of the Facility § 86.31 How much money may I charge the public to use tie-up facilities?...

  4. Evaluation of the Polyethylene Reverse Sampler as a Dosing System in Marine Phase II Whole Sediment Toxicity Identification Evaluations (TIEs)

    EPA Science Inventory

    Contaminated marine sediments can cause acute and chronic impairments to benthic organisms. Nonionic organic contaminants (NOCs) are often a primary cause of impairment. Toxicity Identification Evaluations (TIEs) are used to identify chemicals causing toxicity in sediments. Ph...

  5. USE OF ZEOLITE FOR REMOVING AMMONIA AND AMMONIA-CAUSED TOXCITY IN MARINE TOXICITY IDENTIFCATION EVALUATIONS (TIES)

    EPA Science Inventory

    Ammonia occurs in marine waters including effluents, receiving waters, and sediment interstitial waters. At sufficiently high concentrations, ammonia can be toxic to aquatic species. Toxicity identification evaluation (TIE) methods provide researchers with tools for identifyi...

  6. 77 FR 52352 - Notice of Intent To Prepare an Environmental Impact Statement for the Rio Mesa Gen-Tie Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-29

    ...Mesa Gen-Tie Project and Possible Land Use Plan Amendment, Riverside County...resources, special management areas, land use, noise, paleontological resources...on the findings in the EIS. If a land use plan amendment is necessary,...

  7. 78 FR 75544 - Prestressed Concrete Steel Rail Tie Wire From Mexico: Preliminary Determination of Sales at Less...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ... Countervailing Duty Investigations, 76 FR 61042 (October 3, 2011). International Trade Commission (``ITC... International Trade Administration Prestressed Concrete Steel Rail Tie Wire From Mexico: Preliminary.... SUMMARY: The Department of Commerce (``Department'') preliminarily determines that prestressed...

  8. Small passenger car transmission test: Mercury Lynx ATX transmission

    NASA Technical Reports Server (NTRS)

    Bujold, M. P.

    1981-01-01

    The testing of a Mercury Lynx automatic transmission is reported. The transmission was tested in accordance with a passenger car automatic transmission test code (SAE J65lb) which required drive performance, coast performance, and no load test conditions. Under these conditions, the transmission attained maximum efficiencies in the mid-ninety percent range both for drive performance test and coast performance tests. The torque, speed, and efficiency curves are presented, which provide the complete performance characteristics for the Mercury Lynx automatic transmission.

  9. Small passenger car transmission test: Dodge Omni A-404 transmission

    NASA Technical Reports Server (NTRS)

    Bujold, M. P.

    1980-01-01

    The small passenger car transmission test was initiated to supply electric vehicle manufacturers with technical information regarding the performance of commercially available transmissions. This transmission was tested in accordance with a passenger car automatic transmission test code (SAE J65lb) which required drive performance, coast performance, and no load test conditions. Under these test conditions, the transmission attained maximum efficiencies in the mid eighty percent range for both drive performance test and coast performance tests.

  10. Infinitely variable steering transmission

    SciTech Connect

    Reed, B.O.

    1989-04-04

    A steering transmission is described comprising: first and second drive units each driven at a substantially constant speed for producing respective first and second unidirectional, continuous outputs infinitely variable between a minimum speed and a maximum speed; a first output planetary gear drivingly connected to a first transmission output; a second output planetary gear set drivingly connected to a second transmission output; an input gear set; means interconnecting the first and second output planetary gear sets; means connecting the first drive unit to the first output planetary gear set; means applying the second drive unit output to the second output planetary gear set; means applying a substantially constant speed input to the input gear set; means for selectively conditioning the input gear set to drive the one output planetary gear set at a speed having a first predetermined fixed ratio to the constant speed input, whereby to operate the transmission in one speed range; and means for selectively applying the first drive unit output to second output planetary gear set, whereby to operate the transmission in another speed range different from the one speed range.

  11. Torque feedback transmission

    SciTech Connect

    Whalen, B.L.

    1987-01-20

    This patent describes an infinitely variable transmission of inline configuration for interconnecting a primer mover with a load for clutch free operation in a range of speed including hydraulic neutral comprising: a. planetary gear train means having a ring gear, planetary gears supported by a planetary gear carrier, and a sun gear, the sun gear being connected mechanically to the load, output shaft means for joining the sun gear to the load; b. variable torque feedback means comprising (i) a variable displacement hydraulic motor whose rotor shaft is in line with the output shaft means and drivingly connected to the prime mover and the planetary gear carrier during the full range of operation of the transmission, and (ii) a fixed displacement hydraulic pump connected hydraulically to the motor, the rotor shaft of the pump being connected mechanically to the ring gear and being axially displaced from the output shaft means; c. means for adjusting the displacement volume within the hydraulic motor for controlling the torque feedback in the transmission to provide infinitely variable coupling between the prime mover and the load over the full range of the transmission including hydraulic neutral; d. a speed reducer between the primer mover and the motor rotor shaft and a speed multiplier between the sun gear and the load; and e. mechanical transmission assembly means between the speed multiplier and the load in line with the motor rotor shaft and the output shaft means for providing selection of drive, reverse, park, and neutral.

  12. Ultrahigh Transmission Optical Nanofibers

    E-print Network

    Hoffman, J E; Grover, J A; Solano, P; Kordell, P R; Wong-Campos, J D; Orozco, L A; Rolston, S L

    2014-01-01

    We present a procedure for reproducibly fabricating ultrahigh transmission optical nanofibers (530 nm diameter and 84 mm stretch) with single-mode transmissions of 99.95 $ \\pm$ 0.02%, which represents a loss from tapering of 2.6 $\\,\\times \\,$ 10$^{-5}$ dB/mm when normalized to the entire stretch. When controllably launching the next family of higher-order modes on a fiber with 195 mm stretch, we achieve a transmission of 97.8 $\\pm$ 2.8%, which has a loss from tapering of 5.0 $\\,\\times \\,$ 10$^{-4}$ dB/mm when normalized to the entire stretch. Our pulling and transfer procedures allow us to fabricate optical nanofibers that transmit more than 400 mW in high vacuum conditions. These results, published as parameters in our previous work, present an improvement of two orders of magnitude less loss for the fundamental mode and an increase in transmission of more than 300% for higher-order modes, when following the protocols detailed in this paper. We extract from the transmission during the pull, the only reported...

  13. 2006 Final Transmission Proposal.

    SciTech Connect

    United States. Bonneville Power Administration.

    2005-06-01

    This Record of Decision (ROD) contains the decisions of the Administrator of the Bonneville Power Administration BPABPA with respect to the adoption of transmission and ancillary services rates for the two-year rate period beginning October 1, 2005, and ending September 30, 2007 (fiscal years (FY) 2006-2007)(2006 Final Transmission and Ancillary Services Rate Proposal). These decisions are based on the record compiled in this rate proceeding. The transmission and ancillary services rates adopted in this ROD are the rates proposed as a result of a comprehensive settlement agreement between BPA's Transmission Business Line (BPA-TBL) and a diverse group of transmission customers, including BPA's Power Business Line (BPA-PBL), regional investor-owned utilities, partial and full requirements customers of the BPA-PBL, Direct Services Industrial (DSI) customers, and merchant generators. The decisions in this ROD to adopt the rates and charges proposed by the settlement agreement are not intended to create or imply any factual , legal, procedural or substantive precedent, or to create agreement to any underlying principle or methodology.

  14. Printed circuit dispersive transmission line

    DOEpatents

    Ikezi, H.; Lin-Liu, Y.R.; DeGrassie, J.S.

    1991-08-27

    A printed circuit dispersive transmission line structure is disclosed comprising an insulator, a ground plane formed on one surface of the insulator, a first transmission line formed on a second surface of the insulator, and a second transmission line also formed on the second surface of the insulator and of longer length than the first transmission line and periodically intersecting the first transmission line. In a preferred embodiment, the transmission line structure exhibits highly dispersive characteristics by designing the length of one of the transmission line between two adjacent periodic intersections to be longer than the other. 5 figures.

  15. Automotive transmission linkage system

    SciTech Connect

    Yen, F.Y.; Ardayfio, D.D.

    1990-10-02

    This patent describes a system for converting a manual multi-speed transmission to operate as an automatic-manual transmission, the system being disposed within a vehicle, the transmission having a conventional gearshift lever and a clutch pedal. It comprises: a gearshift position selection panel, the panel being located apart from the gearshift lever, the panel enabling a driver to select the desired gear position of the gearshift lever by manipulating the panel without the necessity of the driver handling the gearshift lever; a controller which transforms the gearshift selection of the driver to an output signal, the signal corresponding to the gearshift position selected by the driver; and actuating means for mechanically repositioning the gearshift lever automatically in accordance with the output signal.

  16. Transmission line capital costs

    SciTech Connect

    Hughes, K.R.; Brown, D.R.

    1995-05-01

    The displacement or deferral of conventional AC transmission line installation is a key benefit associated with several technologies being developed with the support of the U.S. Department of Energy`s Office of Energy Management (OEM). Previous benefits assessments conducted within OEM have been based on significantly different assumptions for the average cost per mile of AC transmission line. In response to this uncertainty, an investigation of transmission line capital cost data was initiated. The objective of this study was to develop a database for preparing preliminary estimates of transmission line costs. An extensive search of potential data sources identified databases maintained by the Bonneville Power Administration (BPA) and the Western Area Power Administration (WAPA) as superior sources of transmission line cost data. The BPA and WAPA data were adjusted to a common basis and combined together. The composite database covers voltage levels from 13.8 to 765 W, with cost estimates for a given voltage level varying depending on conductor size, tower material type, tower frame type, and number of circuits. Reported transmission line costs vary significantly, even for a given voltage level. This can usually be explained by variation in the design factors noted above and variation in environmental and land (right-of-way) costs, which are extremely site-specific. Cost estimates prepared from the composite database were compared to cost data collected by the Federal Energy Regulatory Commission (FERC) for investor-owned utilities from across the United States. The comparison was hampered because the only design specifications included with the FERC data were voltage level and line length. Working within this limitation, the FERC data were not found to differ significantly from the composite database. Therefore, the composite database was judged to be a reasonable proxy for estimating national average costs.

  17. Advanced rotorcraft transmission program

    NASA Technical Reports Server (NTRS)

    Bill, Robert C.

    1990-01-01

    The Advanced Rotorcraft Transmission (ART) program is an Army-funded, joint Army/NASA program to develop and demonstrate lightweight, quiet, durable drivetrain systems for next generation rotorcraft. ART addresses the drivetrain requirements of two distinct next generation aircraft classes: Future Air Attack Vehicle, a 10,000 to 20,000 lb. aircraft capable of undertaking tactical support and air-to-air missions; and Advanced Cargo Aircraft, a 60,000 to 80,000 lb. aircraft capable of heavy life field support operations. Both tiltrotor and more conventional helicopter configurations are included in the ART program. Specific objectives of ART include reduction of drivetrain weight by 25 percent compared to baseline state-of-the-art drive systems configured and sized for the next generation aircraft, reduction of noise level at the transmission source by 10 dB relative to a suitably sized and configured baseline, and attainment of at least a 5000 hr mean-time-between-removal. The technical approach for achieving the ART goals includes application of the latest available component, material, and lubrication technology to advanced concept drivetrains that utilize new ideas in gear configuration, transmission layout, and airframe/drivetrain integration. To date, candidate drivetrain systems were carried to a conceptual design stage, and tradeoff studies were conducted resulting in selection of an ART transmission configuration for each of the four contractors. The final selection was based on comparative weight, noise, and reliability studies. A description of each of the selected ART designs is included. Preliminary design of each of the four selected ART transmission was completed, as have mission impact studies wherein comparisons of aircraft mission performance and life cycle costs are undertaken for the next generation aircraft with ART and with the baseline transmission.

  18. Transmissivity variations in mudstones.

    PubMed

    MacDonald, Alan M; Kemp, Simon J; Davies, Jeff

    2005-01-01

    Many people in sub-Saharan Africa have to rely on meager water resources within mudstones for their only water supply. Although mudstones have been extensively researched for their low permeability behavior, little research has been undertaken to examine their ability to provide sustainable water supplies. To investigate the factors controlling the occurrence of usable ground water in mudstone environments, an area of Cretaceous mudstones in southeastern Nigeria was studied over a 3 yr period. Transmissivity (T) variations in a range of mudstone environments were studied. The investigations demonstrate that within the top 40 m of mudstones, transmissivity can be sufficient to develop village water supplies (T > 1 m2/d). Transmissivity is controlled by two factors: low-grade metamorphism and the presence of other, subordinate, lithologies within the mudstones. Largely unaltered mudstones (early diagenetic zone), comprising mainly smectite clays, are mostly unfractured and have a low T of < 0.1 m2/d. Mudstones that have undergone limited metamorphism (late diagenetic zone) comprise mixed layered illite/smectite clays, and ground water is found in widely spaced fracture zones (T > 1 m2/d in large fracture zones; T < 0.1 m2/d away from fracture zones). Mudstones that have been further altered and approach the anchizone comprise illite clays, are pervasively fractured, and have the highest transmissivity values (T > 4 m2/d). Dolerite intrusions in unaltered, smectitic mudstones are highly fractured with transmissivity in the range of 1 < T < 60 m2/d. Thin limestone and sandstone layers can also enhance transmissivity sufficiently to provide community water supplies. PMID:15819947

  19. Static Dissipative Cable Ties, Such as for Radiation Belt Storm Probes

    NASA Technical Reports Server (NTRS)

    Langley, Patrick T. (Inventor); Siddique, Fazle E. (Inventor)

    2013-01-01

    Methods of cyclically heating and cooling an article formed of a static dissipative ETFE resin, such as to reduce an electrical resistivity and/or to increase a tensile strength of the article, and methods of irradiating an article formed of a static dissipative ETFE resin, such as to increase a tensile strength of the article. Also disclosed herein are articles formed of a static dissipative ETFE resin, and processed in accordance with methods disclosed herein. Such an article may include, for example and without limitation, a cable strap to wrap, support, and/or secure one or more wires or cables, such as a cable tie.

  20. Licklider Transmission Protocol Implementation

    NASA Technical Reports Server (NTRS)

    Burleigh, Scott C.; Krupiarz, Chris

    2011-01-01

    This software is an implementation of the Licklider Transmission Protocol (LTP), a communications protocol intended to support the Bundle Protocol in Delay-Tolerant Network (DTN) operations. LTP is designed to provide retransmission-based reliability over links characterized by extremely long message round-trip times and/or frequent interruptions in connectivity. Communication in interplanetary space is the most prominent example of this sort of environment, and LTP is principally aimed at supporting long-haul reliable transmission over deep-space RF links. Like any reliable transport service employing ARQ (Automatic Repeat re-Quests), LTP is stateful. In order to assure the reception of a block of data it has sent, LTP must retain for possible retransmission all portions of that block which might not have been received yet. In order to do so, it must keep track of which portions of the block are known to have been received so far, and which are not, together with any additional information needed for purposes of retransmitting part, or all, of the block. Long round-trip times mean substantial delay between the transmission of a block of data and the reception of an acknowledgement from the block s destination, signaling arrival of the block. If LTP postponed transmission of additional blocks of data until it received acknowledgement of the arrival of all prior blocks, valuable opportunities to use what little deep space transmission bandwidth is available would be forever lost. For this reason, LTP is based in part on a notion of massive state retention. Any number of requested transmission conversations (sessions) may be concurrently in flight at various displacements along the link between two LTP engines, and the LTP engines must necessarily retain transmission status and retransmission resources for all of them. Moreover, if any of the data of a given block are lost en route, it will be necessary to retain the state of that transmission during an additional round trip while the lost data are retransmitted; even multiple retransmission cycles may be necessary. LTP's possible multiplicity of sessions per association makes it necessary for each segment of application data to include an additional demultiplexing token: a session ID that uniquely identifies the session in which the segment was issued and, implicitly, the block of data being conveyed by this session. This software comprises a prototype implementation developed by Johns Hopkins University APL in cooperation with JPL, together with adaptations that improve the robustness, correctness, and operability of that implementation.

  1. Quantum Anonymous Transmissions

    E-print Network

    Matthias Christandl; Stephanie Wehner

    2005-08-15

    We consider the problem of hiding sender and receiver of classical and quantum bits (qubits), even if all physical transmissions can be monitored. We present a quantum protocol for sending and receiving classical bits anonymously, which is completely traceless: it successfully prevents later reconstruction of the sender. We show that this is not possible classically. It appears that entangled quantum states are uniquely suited for traceless anonymous transmissions. We then extend this protocol to send and receive qubits anonymously. In the process we introduce a new primitive called anonymous entanglement, which may be useful in other contexts as well.

  2. 1/13/11 12:12 PMProstate cancer risk tied to DNA changes; Discovery may spur research Page 1 of 3https://secure.pqarchiver.com/boston/access/1248324341.html?FMT=F...e+cancer+risk+tied+to+DNA+changes%3B+Discovery+may+spur+research

    E-print Network

    Reich, David

    1/13/11 12:12 PMProstate cancer risk tied to DNA changes; Discovery may spur research Page 1 of 3https://secure.pqarchiver.com/boston/access/1248324341.html?FMT=F...e+cancer+risk+tied+to+DNA+changes%3B+Discovery Prostate cancer risk tied to DNA changes; Discovery may spur research [1 Edition] Boston Globe - Boston

  3. The Response of Environmental Capacity for Malaria Transmission in West Africa to Climate Change

    NASA Astrophysics Data System (ADS)

    Yamana, T. K.; Eltahir, E. A.

    2011-12-01

    The climate of West Africa is characterized by north-south gradients in temperature and rainfall. Environmental capacity for malaria transmission (e.g. as measured by vectorial capacity) is strongly tied to these two variables; temperature affects the development rate of the malaria parasite, as well as the lifespan of the mosquitoes that transmit the disease, and rainfall is tied to mosquito abundance, as the vector lays its eggs in rain-fed water pools. A change in climate is therefore expected to lead to changes in the distribution of malaria transmission. Current general circulation models agree that the temperature in West Africa is expected to increase by several degrees in the next century. However they predict a wide range of possible rainfall scenarios in the future, from intense drying to significant increases in rainfall (Christensen et al., 2007). The effects these changes will have on environmental capacity for malaria transmission depend on the magnitude and direction of the changes, and on current conditions. For example, malaria transmission will be more sensitive to positive changes in rainfall in dry areas where mosquito populations are currently limited by water availability than in relatively wet areas. Here, we analyze combinations of changes in rainfall and temperature within the ranges predicted by GCMs, and assess the impact these combinations will have on the environmental capacity for malaria transmission. In particular, we identify climate change scenarios that are likely to have the greatest impact on environmental capacity for malaria transmission, as well as geographic "hot spots" where the greatest changes are to be expected. Christensen, J. H., Busuioc, A., & et al. (2007). Regional climate projections. In S. Solomon (Ed.), Climate change 2007: The physical science basis. Contribution of Working Group I to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change.

  4. Laser power transmission

    NASA Technical Reports Server (NTRS)

    Conway, Edmund J.

    1992-01-01

    An overview of previous studies related to laser power transmission is presented. Particular attention is given to the use of solar pumped lasers for space power applications. Three general laser mechanisms are addressed: photodissociation lasing driven by sunlight, photoexcitation lasing driven directly by sunlight, and photoexcitation lasing driven by thermal radiation.

  5. Autonomous data transmission apparatus

    DOEpatents

    Kotlyar, Oleg M. (4675 W. 3825 S, Salt Lake City, UT 84120)

    1997-01-01

    A autonomous borehole data transmission apparatus for transmitting measurement data from measuring instruments at the downhole end of a drill string by generating pressure pulses utilizing a transducer longitudinally responsive to magnetic field pulses caused by electrical pulses corresponding to the measured downhole parameters.

  6. Continuously variable transmission

    SciTech Connect

    Itoh, H.; Okada, M.

    1986-11-25

    This patent describes a continuously variable transmission for transmitting a torque from an engine to a final reduction gear, comprising: an input shaft connected with the engine at one end thereof; a continuously variable transmission means having a driving pulley with a fixed member and a movable member, the movable member being actuated by an hydraulic cylinder to form a V-shaped opening between the fixed member and movable member, a driven pulley with another fixed member and another movable member. The other movable member is similarly actuated by another hydraulic cylinder to form another V-shaped opening between the other fixed member and the other movable member, and a belt member spanning the pulleys provides for a continuously variable transmission ratio; a planetary gear unit including a sun gear, a plurality of pinion gears which mesh with the sun gear and are connected with the driven pulley and a ring gear which meshes with the plurality of pinion gears; and a rotation transmitting means for transmitting rotation of the input shaft to the planetary gear unit. The rotation transmitting means is provided between the input shaft and the planetary gear unit and includes a shaft connected with the sun gear of the planetary gear unit and a first gear connected with the input shaft. The first gear is located between the engine and the continuously variable transmission means.

  7. Categories and Music Transmission

    ERIC Educational Resources Information Center

    Gatien, Greg

    2009-01-01

    Lucy Green's (2008) "Music, Informal Learning, and the School: A New Classroom Pedagogy" gives rise to an interesting corollary. Does the manner of music's transmission inform one's understanding of a musical category? While categories of music can be difficult to define according to strict musical characteristics, a better understanding of…

  8. Borehole data transmission apparatus

    DOEpatents

    Kotlyar, Oleg M. (1739 Grandview #2, Idaho Falls, ID 83402)

    1993-01-01

    A borehole data transmission apparatus whereby a centrifugal pump impeller(s) is used to provide a turbine stage having substantial pressure characteristics in response to changing rotational speed of a shaft for the pressure pulsing of data from the borehole through the drilling mud to the surface of the earth.

  9. Borehole data transmission apparatus

    DOEpatents

    Kotlyar, O.M.

    1993-03-23

    A borehole data transmission apparatus is described whereby a centrifugal pump impeller(s) is used to provide a turbine stage having substantial pressure characteristics in response to changing rotational speed of a shaft for the pressure pulsing of data from the borehole through the drilling mud to the surface of the earth.

  10. Autonomous data transmission apparatus

    DOEpatents

    Kotlyar, O.M.

    1997-03-25

    A autonomous borehole data transmission apparatus is described for transmitting measurement data from measuring instruments at the downhole end of a drill string by generating pressure pulses utilizing a transducer longitudinally responsive to magnetic field pulses caused by electrical pulses corresponding to the measured downhole parameters. 4 figs.

  11. Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB

    PubMed Central

    Uebelhoer, Melanie; Nätynki, Marjut; Kangas, Jaakko; Mendola, Antonella; Nguyen, Ha-Long; Soblet, Julie; Godfraind, Catherine; Boon, Laurence M.; Eklund, Lauri; Limaye, Nisha; Vikkula, Miikka

    2013-01-01

    Mutations in the endothelial cell (EC) tyrosine kinase receptor TIE2 cause inherited and sporadic forms of venous malformation. The recurrent somatic mutation L914F and common germline mutation R849W differ in terms of phosphorylation level, as well as sub-cellular localization and trafficking of the receptor. Previous studies have shed light on certain pathogenic properties of R849W, but the mechanisms of action of L914F are unknown. We used global gene expression profiling to study the effects of L914F on ECs. We found that L914F strongly dysregulates genes involved in vascular development, cell migration and extracellular matrix processing, while R849W has weak effects. We also demonstrate, for the first time, that TIE2-mutant ECs are deficient in the production of PDGFB, both in vitro and ex vivo in patient tissues. This defect is mediated by the chronic, ligand-independent activation of AKT by the mutant receptors. Inadequate secretion of the major mural cell attractant likely plays an important role in the development of abnormal vascular channels, contributing to the characteristic paucity of surrounding vascular smooth muscle cells. PMID:23633549

  12. Ground-state magnetic phase diagram of bow-tie graphene nanoflakes in external magnetic field

    SciTech Connect

    Sza?owski, Karol E-mail: kszalowski@wp.pl

    2013-12-28

    The magnetic phase diagram of a ground state is studied theoretically for graphene nanoflakes of bow-tie shape and various sizes in external in-plane magnetic field. The tight-binding Hamiltonian supplemented with Hubbard term is used to model the electronic structure of the systems in question. The existence of the antiferromagnetic phase with magnetic moments localized at the sides of the bow-tie is found for low field and a field-induced spin-flip transition to ferromagnetic state is predicted to occur in charge-undoped structures. For small nanoflake doped with a single charge carrier, the low-field phase is ferrimagnetic and a metamagnetic transition to ferromagnetic ordering can be forced by the field. The critical field is found to decrease with increasing size of the nanoflake. The influence of diagonal and off-diagonal disorder on the mentioned magnetic properties is studied. The effect of off-diagonal disorder is found to be more important than that of diagonal disorder, leading to significantly widened distribution of critical fields for disordered population of nanoflakes.

  13. Conductivities consistent with Birkeland currents in the AMPERE-driven TIE-GCM

    NASA Astrophysics Data System (ADS)

    Marsal, S.

    2015-09-01

    The Active Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE) satellite mission has offered for the first time global snapshots of the geomagnetic field-aligned currents with unprecedented space and time resolution, thus providing an opportunity to feed an acknowledged first-principles model of the Earth's upper atmosphere such as the National Center for Atmospheric Research Thermosphere-Ionosphere-Electrodynamics General Circulation Model (NCAR TIE-GCM). In the first step, Marsal et al. (2012) used AMPERE data in the current continuity equation between the magnetosphere and the ionosphere to drive the TIE-GCM electrodynamics. In the present work, ionospheric conductivities have been made consistent with enhanced upward field-aligned currents, which are assumed to correspond to electrons plunging as a result of downward acceleration by electric fields built up along the geomagnetic field lines. The resulting conductance distribution is reasonably commensurate with an independent model that has tried to quantify the ionizing effect of precipitating particles onto the auroral ionosphere. On the other hand, comparison of geomagnetic observatory data with the ground magnetic variations output by the model only shows a modest improvement with respect to our previous approach.

  14. Use of a Barbed Suture Tie-Over Technique for Skin Graft Dressings: A Case Series

    PubMed Central

    Joyce, Cormac W; Mahon, Nicola; Kelly, Jack L

    2015-01-01

    Background A tie-over dressing is the accepted method to secure skin grafts in order to prevent haematoma or seroma formation. We describe the novel application of a barbed suture tie-over for skin graft dressing. The barbs act as anchors in the skin so constant tensioning of the suture is not required. Methods From January 2014 to August 2014 we used the technique in 30 patients with skin defects requiring split-thickness or full-thickness grafts. Patient demographics, clinicopathological details and graft outcome were collected prospectively. Results The majority of cases were carried out for split-thickness skin grafts (n=19) used on the lower limb (n=20). The results of this novel technique were excellent with complete (100%) graft take in all patients. Conclusions Our results demonstrate the clinical application of a barbed device for securing skin grafts with excellent results. We find the technique quick to perform and the barbed device easy to handle, which can be applied without the need for an assistant. PMID:26015891

  15. Quasi-separatrix layers and three-dimensional reconnection diagnostics for line-tied tearing modes

    E-print Network

    Richardson, A S

    2011-01-01

    In three-dimensional magnetic configurations for a plasma in which no closed field line or magnetic null exists, no magnetic reconnection can occur, by the strictest definition of reconnection. A finitely long pinch with line-tied boundary conditions, in which all the magnetic field lines start at one end of the system and proceed to the opposite end, is an example of such a system. Nevertheless, for a long system of this type, the physical behavior in resistive magnetohydrodynamics (MHD) essentially involves reconnection. This has been explained in terms comparing the geometric and tearing widths [1, 2]. The concept of a quasi-separatrix layer[3, 4] was developed for such systems. In this paper we study a model for a line-tied system in which the corresponding periodic system has an unstable tearing mode. We analyze this system in terms of two magnetic field line diagnostics, the squashing factor[3-5] and the electrostatic potential difference used in kinematic reconnection studies[6, 7]. We discuss the phys...

  16. Small passenger car transmission test; Ford C4 transmission

    NASA Technical Reports Server (NTRS)

    Bujold, M. P.

    1980-01-01

    A 1979 Ford C4 automatic transmission was tested per a passenger car automatic transmission test code (SAE J651b) which required drive performance, coast performance, and no load test conditions. Under these test conditions, the transmission attained maximum efficiencies in the mid-eighty percent range for both drive performance tests and coast performance tests. The major results of this test (torque, speed, and efficiency curves) are presented. Graphs map the complete performance characteristics for the Ford C4 transmission.

  17. Small passenger car transmission test; Chevrolet LUV transmission

    NASA Technical Reports Server (NTRS)

    Bujold, M. P.

    1980-01-01

    A 1978 Chevrolet LUV manual transmission tested per the applicable portions of a passenger car automatic transmission test code (SAE J65lb) which required drive performance, coast performance, and no load test conditions. Under these test conditions, the transmission attained maximum efficiencies in the upper ninety percent range for both drive performance tests and coast performance tests. The major results of this test (torque, speed, and efficiency curves) are presented. Graphs map the complete performance characteristics for the Chevrolet LUV transmission.

  18. Stereo sequence transmission via conventional transmission channel

    NASA Astrophysics Data System (ADS)

    Lee, Ho-Keun; Kim, Chul-Hwan; Han, Kyu-Phil; Ha, Yeong-Ho

    2003-05-01

    This paper proposes a new stereo sequence transmission technique using digital watermarking for compatibility with conventional 2D digital TV. We, generally, compress and transmit image sequence using temporal-spatial redundancy between stereo images. It is difficult for users with conventional digital TV to watch the transmitted 3D image sequence because many 3D image compression methods are different. To solve such a problem, in this paper, we perceive the concealment of new information of digital watermarking and conceal information of the other stereo image into three channels of the reference image. The main target of the technique presented is to let the people who have conventional DTV watch stereo movies at the same time. This goal is reached by considering the response of human eyes to color information and by using digital watermarking. To hide right images into left images effectively, bit-change in 3 color channels and disparity estimation according to the value of estimated disparity are performed. The proposed method assigns the displacement information of right image to each channel of YCbCr on DCT domain. Each LSB bit on YCbCr channels is changed according to the bits of disparity information. The performance of the presented methods is confirmed by several computer experiments.

  19. Towards a better knot: Using mechanics methods to evaluate three knot-tying techniques in laparo-endoscopic single-site surgery

    PubMed Central

    Xu, An An; Zhu, Jiang Fan; Su, Yuantao

    2015-01-01

    INTRODUCTION: Knot tying is difficult but important for laparo-endoscopic single-site surgery (LESS). There are several techniques for LESS knot-tying. However, objective assessment of these skills has not yet been established. The aim of this study was to assess three different knot-tying techniques in LESS using mechanical methods. MATERIALS AND METHODS: The subject tied 24 knots, eight knots with each of the three techniques in an inanimate box laparoscopic trainer while the movements of their instruments were evaluated using a LESS mechanical evaluation platform. The operations were assessed on the basis of the time, average load of the dominant hand. Then, forces caused the knots to rupture were measured using a material testing system and used to compare the knots's strength. RESULTS: The intracorporeal one-hand knot-tying technique presented significantly better time and average load scores than the extracorporeal knot-tying technique (P < 0.01), and the intracorporeal side winding technique was more time and average load consuming in comparison to other techniques during the performance of knot-tying (P < 0.01). The intracorporeal one-handed knot-tying knots can tolerate better distraction forces compared with the intracorporeal side winding knot-tying knots and the extracorporeal knot-tying knots (P < 0.05). CONCLUSIONS: The intracorporeal one-hand knot-tying technique and knots showed better results than the intracorporeal “side winding” technique and the extracorporeal knot-tying technique in terms of the time, average load taken and the force caused the knot to rupture. PMID:26622113

  20. Tie-dyed2 Encodes a Callose Synthase That Functions in Vein Development and Affects Symplastic Trafficking within the Phloem of Maize Leaves12[C][W][OA

    PubMed Central

    Slewinski, Thomas L.; Baker, R. Frank; Stubert, Adam; Braun, David M.

    2012-01-01

    The tie-dyed2 (tdy2) mutant of maize (Zea mays) displays variegated green and yellow leaves. Intriguingly, the yellow leaf tissues hyperaccumulate starch and sucrose, the soluble sugar transported long distance through the phloem of veins. To determine the molecular basis for Tdy2 function, we cloned the gene and found that Tdy2 encodes a callose synthase. RNA in situ hybridizations revealed that in developing leaves, Tdy2 was most highly expressed in the vascular tissue. Comparative expression analysis with the vascular marker maize PINFORMED1a-yellow fluorescent protein confirmed that Tdy2 was expressed in developing vein tissues. To ascertain whether the defect in tdy2 leaves affected the movement of sucrose into the phloem or its long-distance transport, we performed radiolabeled and fluorescent dye tracer assays. The results showed that tdy2 yellow leaf regions were defective in phloem export but competent in long-distance transport. Furthermore, transmission electron microscopy of tdy2 yellow leaf regions showed incomplete vascular differentiation and implicated a defect in cell-to-cell solute movement between phloem companion cells and sieve elements. The disruption of sucrose movement in the phloem in tdy2 mutants provides evidence that the Tdy2 callose synthase functions in vascular maturation and that the vascular defects result in impaired symplastic trafficking into the phloem translocation stream. PMID:22932757

  1. Drill string transmission line

    DOEpatents

    Hall, David R. (Provo, UT); Hall, Jr., H. Tracy (Provo, UT); Pixton, David S. (Lehi, UT); Bradford, Kline (Orem, UT); Fox, Joe (Spanish Fork, UT)

    2006-03-28

    A transmission line assembly for transmitting information along a downhole tool comprising a pin end, a box end, and a central bore traveling between the pin end and the box end, is disclosed in one embodiment of the invention as including a protective conduit. A transmission line is routed through the protective conduit. The protective conduit is routed through the central bore and the ends of the protective conduit are routed through channels formed in the pin end and box end of the downhole tool. The protective conduit is elastically forced into a spiral or other non-linear path along the interior surface of the central bore by compressing the protective conduit to a length within the downhole tool shorter than the protective conduit.

  2. Transmission eigenvalues for elliptic operators

    E-print Network

    Michael Hitrik; Katsiaryna Krupchyk; Petri Ola; Lassi Päivärinta

    2010-07-03

    A reduction of the transmission eigenvalue problem for multiplicative sign-definite perturbations of elliptic operators with constant coefficients to an eigenvalue problem for a non-selfadjoint compact operator is given. Sufficient conditions for the existence of transmission eigenvalues and completeness of generalized eigenstates for the transmission eigenvalue problem are derived. In the trace class case, the generic existence of transmission eigenvalues is established.

  3. Compact change speed transmission

    SciTech Connect

    Iwanaga, K.; Yamaguchi, T.

    1989-06-06

    A change speed transmission is described comprising: a stationary part; an input member; an output member; first and second planetary gear sets; clutch and brake means for selectively controlling the first and second planetary gear sets to provide a plurality of forward speed rations and a reverse speed ratio between the input and output member; the clutch and brake means including a first clutch, a first one-way clutch, and a second one-way clutch which, when the first clutch is engaged, provide a path of transmission of reaction to the stationary part thereby establishing a path of transmission of torque through at least a part of the first and second planetary gear sets to achieve a predetermined one speed ratio of the forward speed ratios; the clutch and brake means including also a brake and a second slutch which, when both of the brake and the second clutch are engaged, hinder the action of the second one-way clutch and that of the first one-way clutch, respectively, thereby providing engine braking during running with the predetermined one speed ratio; the first clutch including means forming a drum-shaped member disposed radially outwardly of and receiving at least one of the first and second planetary gear sets, and an actuating piston of the first clutch; and the second clutch including an actuating piston slidably disposed within the actuating piston of the first clutch.

  4. Intrasperm vertical symbiont transmission

    PubMed Central

    Watanabe, Kenji; Yukuhiro, Fumiko; Matsuura, Yu; Fukatsu, Takema; Noda, Hiroaki

    2014-01-01

    Symbiotic bacteria are commonly associated with cells and tissues of diverse animals and other organisms, which affect hosts’ biology in a variety of ways. Most of these symbionts are present in the cytoplasm of host cells and maternally transmitted through host generations. The paucity of paternal symbiont transmission is likely relevant to the extremely streamlined sperm structure: the head consisting of condensed nucleus and the tail made of microtubule bundles, without the symbiont-harboring cytoplasm that is discarded in the process of spermatogenesis. Here, we report a previously unknown mechanism of paternal symbiont transmission via an intrasperm passage. In the leafhopper Nephotettix cincticeps, a facultative Rickettsia symbiont was found not only in the cytoplasm but also in the nucleus of host cells. In male insects, strikingly, most sperm heads contained multiple intranuclear Rickettsia cells. The Rickettsia infection scarcely affected the host fitness including normal sperm functioning. Mating experiments revealed both maternal and paternal transmission of the Rickettsia symbiont through host generations. When cultured with mosquito and silkworm cell lines, the Rickettsia symbiont was preferentially localized within the insect cell nuclei, indicating that the Rickettsia symbiont itself must have a mechanism for targeting nucleus. The mechanisms underlying the sperm head infection without disturbing sperm functioning are, although currently unknown, of both basic and applied interest. PMID:24799707

  5. Disturbance legacies of historic tie-drives persistently alter geomorphology and large wood characteristics in headwater streams, southeast Wyoming

    NASA Astrophysics Data System (ADS)

    Ruffing, Claire M.; Daniels, Melinda D.; Dwire, Kathleen A.

    2015-02-01

    Instream wood is recognized as an integral component of stream morphology in forested areas. However, few studies have evaluated the legacy effects of historic wood removal activities and associated impacts on channel morphology, contemporary wood loading, and recruitment. This study investigates the role of historic tie-driving, a widespread channel disturbance legacy, in shaping present-day stream channel conditions in southern Wyoming. Geomorphic and riparian surveys were used to assess the extent of disturbance and degree of recovery within three sets of paired tie-driven and non-driven study reaches. Tie-driven streams were narrower, shallower, and had low cross-sectional roughness and higher width-to-depth ratios when compared to non-driven streams. Study reaches in first-order tie-driven streams were characterized by predominantly plane-bed morphologies and an extremely low abundance of wood compared to paired, non-driven reaches. Wood loads in second-order tie-driven reaches were similar to non-driven reaches, but overall wood distribution varied and was more likely to accumulate in jams. Existing wood loads in tie-driven reaches exhibited a narrower range of geomorphic functions and were less stable overall, although the relative state of decay was similar across all reaches. Basal area, stream power, and reach slope were identified as key mechanisms driving wood retention in the study reaches. The results of this study suggest that contemporary channel morphology and wood loads continue to reflect disturbance histories but have not yet been affected by other contemporary disturbances expected to influence wood loads such as bark beetle infestations.

  6. Digital Transmission System Signaling Protocol

    E-print Network

    Groppi, Christopher

    Digital Transmission System Signaling Protocol EVLA Memorandum No. 33 Version 3 A modified version of "Digital Transmission System Signaling Protocol", Written by Robert W. Freund, September 25, 2000. Prepared by Steven Durand November, 2001 #12;EVLA Digital Transmission System Signaling Protocol EVLA Memorandum 33

  7. Molecular ties between the cell cycle and differentiation in embryonic stem cells.

    PubMed

    Li, Victor C; Kirschner, Marc W

    2014-07-01

    Attainment of the differentiated state during the final stages of somatic cell differentiation is closely tied to cell cycle progression. Much less is known about the role of the cell cycle at very early stages of embryonic development. Here, we show that molecular pathways involving the cell cycle can be engineered to strongly affect embryonic stem cell differentiation at early stages in vitro. Strategies based on perturbing these pathways can shorten the rate and simplify the lineage path of ES differentiation. These results make it likely that pathways involving cell proliferation intersect at various points with pathways that regulate cell lineages in embryos and demonstrate that this knowledge can be used profitably to guide the path and effectiveness of cell differentiation of pluripotent cells. PMID:24979803

  8. The design and development of a spacecraft appendage tie down mechanism

    NASA Technical Reports Server (NTRS)

    Nygren, W. D.; Head, R.

    1985-01-01

    The design and evolution is described of a spacecraft Appendage Tie Down Mechanism (ATDM). Particular emphasis is paid to the mechanical aspects of using dry lubricants to increase the efficiency of acme threads and worm gearing. The ATDM consists of five major components. These are a dc torque motor, a worm gear speed reducer, the tension bolt (or T-bolt), nut capture and centering jaws and the capture nut. In addition, there are several minor components such as limit switch assemblies and an antibackdrive mechanism which couples the drive motor to the worm shaft. A development model of the ATDM in various configurations was under test for some time. In its latest version, it has successfully completed thermal vacuum testing, vibration testing, and extended life testing.

  9. Molecular ties between the cell cycle and differentiation in embryonic stem cells

    PubMed Central

    Li, Victor C.; Kirschner, Marc W.

    2014-01-01

    Attainment of the differentiated state during the final stages of somatic cell differentiation is closely tied to cell cycle progression. Much less is known about the role of the cell cycle at very early stages of embryonic development. Here, we show that molecular pathways involving the cell cycle can be engineered to strongly affect embryonic stem cell differentiation at early stages in vitro. Strategies based on perturbing these pathways can shorten the rate and simplify the lineage path of ES differentiation. These results make it likely that pathways involving cell proliferation intersect at various points with pathways that regulate cell lineages in embryos and demonstrate that this knowledge can be used profitably to guide the path and effectiveness of cell differentiation of pluripotent cells. PMID:24979803

  10. Source and event selection for radio-planetary frame-tie measurements using the Phobos Landers

    NASA Technical Reports Server (NTRS)

    Linfield, R.; Ulvestad, J.

    1988-01-01

    The Soviet Phobos Lander mission will place two spacecraft on the Martian moon Phobos in 1989. Measurements of the range from Earth-based stations to the landers will allow an accurate determination of the ephemerides of Phobos and Mars. Delta Very Long Base Interferometry (VLBI) between the landers and compact radio sources nearby on the sky will be used to obtain precise estimates of the angular offset between the radio and planetary reference frames. The accuracy of this frame-tie estimate is expected to be in the vicinity of 10 mrad, depending on how well several error sources can be controlled (calibrated or reduced). Many candidate radio sources for VLBI measurements were identified, but additional work is necessary to select those sources which have characteristics appropriate to the present application. Strategies for performing the source selection are described.

  11. Public Response to Residential Grid-Tied PV Systems in Colorado: A Qualitative Market Assessment

    SciTech Connect

    Farhar, B. C.; Buhrmann, J.

    1998-07-01

    The early adopters of residential grid-tied photovoltaics (PV) have complex motivations to pay today's costs, including altruistic, environmental, and financial reasons. Focused interviews were conducted with a self-selected purposive sample interested in purchasing 2-kW or 3-kW PV systems with an installed cost of $8,000 to $12,000. The sample tended to be men or married couples ranging in age from their early thirties to their mid-eighties; professionals, managers, or small business owners; relatively financially secure, with experience with energy efficiency and renewable energy. Product attributes they preferred were net metering, warranties, guarantees, utility financing, maintenance, an option to own or lease, a battery option, and an aesthetically pleasing system. Potential PV customers needed more information before making a purchase decision.

  12. Impact of Inter-technique Vector Tie Errors at Future GGOS Core Sites on the ITRF

    NASA Astrophysics Data System (ADS)

    Pavlis, Erricos C.; Kuzmicz-Cieslak, Magdalena

    2013-04-01

    The Global Geodetic Observing System—GGOS, has identified as its main task the establishment, maintenance and wide distribution of the International Terrestrial Reference Frame (ITRF), requiring a high accuracy and stability goal set at 1 mm and 0.1 mm/y. The four "geometric" Services of the International Association of Geodesy (IAG), IDS, IGS, ILRS and IVS are responsible for the provision of the required analysis products that form the input in the ITRF development step. The network of sites that will host all four techniques with an optimal global distribution comprises the so-called "GGOS Core Sites Network—GCSN". Simulation studies over the past few years determined the size and distribution of the sites in order to meet the goals of GGOS. Assuming that all techniques are present with their state-of-the-art equipment, it has been determined that a network of about thirty sites is sufficient to achieve our goal. This result presupposes the ability of the techniques to relate their reference points, those to which their results refer, to a common one representing the site, with an accuracy that is better than 1 mm at any time. These "survey ties" between the invariant reference points between techniques are the subject of extensive research, theoretical as well as practical, in order to develop a modus operandi that realizes with certainty the required accuracy ties at all sites. One can separate the problem for each of the techniques into two distinct components: the survey that determines the offset of the common marker to a physical point of reference on the antenna or telescope used by the technique, and a second much more difficult to determine offset, of the physical point from the actual electronic or optical invariant point to which the observations of each technique refer. The first part is rather easily controlled with precision surveying, most likely through automated procedures using modern technology. The second part is the most difficult to determine and depends on several factors, from the type of the technique in question, to environmental changes, to tracking geometry and local conditions specific to each site. So far, the assumption is that the combined error from the two parts remains ~1 mm. This is a topic of separate studies for each of the contributing techniques. A question that requires an answer before the final design of the survey system is the actual level of total error that one can tolerate at each site, before the GGOS network accuracy goal is compromised. Our presentation focuses on this question using simulations of survey errors at the core sites of a 32-site GCSN, with varying distribution of the site-tie errors in terms of the level of the errors as well as a function of the contributing techniques. These simulations will provide some guidelines on the level of effort that each of the techniques should devote in determining the technique-specific error component and the improvement (if any) required for the common survey tie component at each site.

  13. Impact of Survey Tie Errors in the GGOS Core Site Network on the ITRF

    NASA Astrophysics Data System (ADS)

    Pavlis, E. C.; Kuzmicz-Cieslak, M.

    2012-04-01

    The Global Geodetic Observing System—GGOS, has identified as its main task the establishment, maintenance and wide distribution of the International Terrestrial Reference Frame (ITRF), requiring a high accuracy and stability goal set at 1 mm and 0.1 mm/y. The four "geometric" Services of the International Association of Geodesy (IAG), IDS, IGS, ILRS and IVS are responsible for the provision of the required analysis products that form the input in the ITRF development step. The network of sites that will host all four techniques with an optimal global distribution comprises the so-called "GGOS Core Sites Network—GCSN". Simulation studies over the past few years determined the size and distribution of the sites in order to meet the goals of GGOS. Assuming that all techniques are present with their state-of-the-art equipment, it has been determined that a network of about thirty sites is sufficient to achieve our goal. This result presupposes the ability of the techniques to relate their reference points, those to which their results refer, to a common one representing the site, with an accuracy that is better than 1 mm at any time. These "survey ties" between the invariant reference points between techniques are the subject of extensive research, theoretical as well as practical, in order to develop a modus operandi that realizes with certainty the required accuracy ties at all sites. One can separate the problem for each of the techniques into two distinct components: the survey that determines the offset of the common marker to a physical point of reference on the antenna or telescope used by the technique, and a second much more difficult to determine offset, of the physical point from the actual electronic or optical invariant point to which the observations of each technique refer. The first part is rather easily controlled with precision surveying, most likely through automated procedures using modern technology. The second part is the most difficult to determine and depends on several factors, from the type of the technique in question, to environmental changes, to tracking geometry and local conditions specific to each site. So far, the assumption is that the combined error from the two parts remains 1 mm. This is a topic of separate studies for each of the contributing techniques. A question that requires an answer before the final design of the survey system is the actual level of total error that one can tolerate at each site, before the GGOS network accuracy goal is compromised. Our presentation focuses on this question using simulations of survey errors at the core sites of a 32-site GCSN, with varying distribution of the site-tie errors in terms of the level of the errors as well as a function of the contributing techniques. These simulations will provide some guidelines on the level of effort that each of the techniques should devote in determining the technique-specific error component and the improvement (if any) required for the common survey tie component at each site.

  14. Transnational ties and past-year major depressive episodes among Latino immigrants.

    PubMed

    Alcántara, Carmela; Chen, Chih-Nan; Alegría, Margarita

    2015-07-01

    Latino immigrants live in an increasingly global world in which maintaining contact with kin in the home country is easier than ever. We examined (a) the annual distribution of remittances burden (percentage of remittances/household income) and visits to the home country, (b) the association of these transnational ties with a past-year major depressive episode (MDE), and (c) moderation by Latino subethnicity or gender. We conducted weighted logistic regression analyses with the Latino immigrant subsample (N = 1,614) of the National Latino and Asian American Study. Mexican and Other Latino immigrants had greater remittances burden than Puerto Rican migrants. Cuban immigrants made the fewest visits back home. After adjustment for sociodemographics and premigration psychiatric history, remittances burden decreased odds of MDE (odds ratio [OR] = 0.80, 95% confidence interval [CI] [0.67, .0.98]), whereas visits back home increased odds of MDE (OR = 1.04, 95% CI [1.01, 1.06]). Latino subethnicity was not a significant moderator. Visits back home were more strongly linked to depression among women than men. The distribution of transnational ties differs by Latino subgroup, although its association with depression is similar across groups. Monetary giving through remittances might promote a greater sense of self-efficacy, and caregiving for relatives back home that positively affect mental health. Visits back home, especially for women, might signal social stress from strained relationships with kin, spouses, or children left behind, or increased caregiving demands that negatively affect mental health. Clinical practice with immigrants should routinely assess the social resources and strains that fall outside national borders. PMID:25090146

  15. LOFAR tied-array imaging and spectroscopy of solar S bursts

    NASA Astrophysics Data System (ADS)

    Morosan, D. E.; Gallagher, P. T.; Zucca, P.; O'Flannagain, A.; Fallows, R.; Reid, H.; Magdaleni?, J.; Mann, G.; Bisi, M. M.; Kerdraon, A.; Konovalenko, A. A.; MacKinnon, A. L.; Rucker, H. O.; Thidé, B.; Vocks, C.; Alexov, A.; Anderson, J.; Asgekar, A.; Avruch, I. M.; Bentum, M. J.; Bernardi, G.; Bonafede, A.; Breitling, F.; Broderick, J. W.; Brouw, W. N.; Butcher, H. R.; Ciardi, B.; de Geus, E.; Eislöffel, J.; Falcke, H.; Frieswijk, W.; Garrett, M. A.; Grießmeier, J.; Gunst, A. W.; Hessels, J. W. T.; Hoeft, M.; Karastergiou, A.; Kondratiev, V. I.; Kuper, G.; van Leeuwen, J.; McKay-Bukowski, D.; McKean, J. P.; Munk, H.; Orru, E.; Paas, H.; Pizzo, R.; Polatidis, A. G.; Scaife, A. M. M.; Sluman, J.; Tasse, C.; Toribio, M. C.; Vermeulen, R.; Zarka, P.

    2015-08-01

    Context. The Sun is an active source of radio emission that is often associated with energetic phenomena ranging from nanoflares to coronal mass ejections (CMEs). At low radio frequencies (<100 MHz), numerous millisecond duration radio bursts have been reported, such as radio spikes or solar S bursts (where S stands for short). To date, these have neither been studied extensively nor imaged because of the instrumental limitations of previous radio telescopes. Aims: Here, LOw Frequency ARray (LOFAR) observations were used to study the spectral and spatial characteristics of a multitude of S bursts, as well as their origin and possible emission mechanisms. Methods: We used 170 simultaneous tied-array beams for spectroscopy and imaging of S bursts. Since S bursts have short timescales and fine frequency structures, high cadence (~50 ms) tied-array images were used instead of standard interferometric imaging, that is currently limited to one image per second. Results: On 9 July 2013, over 3000 S bursts were observed over a time period of ~8 h. S bursts were found to appear as groups of short-lived (<1 s) and narrow-bandwidth (~2.5 MHz) features, the majority drifting at ~3.5 MHz s-1 and a wide range of circular polarisation degrees (2-8 times more polarised than the accompanying Type III bursts). Extrapolation of the photospheric magnetic field using the potential field source surface (PFSS) model suggests that S bursts are associated with a trans-equatorial loop system that connects an active region in the southern hemisphere to a bipolar region of plage in the northern hemisphere. Conclusions: We have identified polarised, short-lived solar radio bursts that have never been imaged before. They are observed at a height and frequency range where plasma emission is the dominant emission mechanism, however, they possess some of the characteristics of electron-cyclotron maser emission. A movie associated to Fig. 3 is available in electronic form at http://www.aanda.org

  16. Gender Differences in Physicians’ Financial Ties to Industry: A Study of National Disclosure Data

    PubMed Central

    Rose, Susannah L.; Sanghani, Ruchi M.; Schmidt, Cory; Karafa, Matthew T.; Kodish, Eric; Chisolm, Guy M.

    2015-01-01

    Background Academic literature extensively documents gender disparities in the medical profession with regard to salary, promotion, and government funded research. However, gender differences in the value of financial ties to industry have not been adequately studied despite industry’s increasing contribution to income and research funding to physicians in the U.S. Methods & Findings We analyzed publicly reported financial relationships among 747,603 physicians and 432 pharmaceutical, device and biomaterials companies. Demographic and payment information were analyzed using hierarchical regression models to determine if statistically significant gender differences exist in physician-industry interactions regarding financial ties, controlling for key covariates. In 2011, 432 biomedical companies made an excess of $17,991,000 in payments to 220,908 physicians. Of these physicians, 75.1% were male. Female physicians, on average, received fewer total dollars (-$3,598.63, p<0.001) per person than men. Additionally, female physicians received significantly lower amounts for meals (-$41.80, p<0.001), education (-$1,893.14, p<0.001), speaker fees (-$2,898.44, p<0.001), and sponsored research (-$15,049.62, p=0.05). For total dollars, an interaction between gender and institutional reputation was statistically significant, implying that the differences between women and men differed based on industry’s preference for an institution, with larger differences at higher reputation institutions. Conclusions Female physicians receive significantly lower compensation for similarly described activities than their male counterparts after controlling for key covariates. As regulations lead to increased transparency regarding these relationships, efforts to standardize compensation should be considered to promote equitable opportunities for all physicians. PMID:26067810

  17. Cow comfort in tie-stalls: increased depth of shavings or straw bedding increases lying time.

    PubMed

    Tucker, C B; Weary, D M; von Keyserlingk, M A G; Beauchemin, K A

    2009-06-01

    Over half of US dairy operations use tie-stalls, but these farming systems have received relatively little research attention in terms of stall design and management. The current study tested the effects of the amount of 2 bedding materials, straw and shavings, on dairy cattle lying behavior. The effects of 4 levels of shavings, 3, 9, 15, and 24 kg/stall (experiment 1, n = 12), and high and low levels of straw in 2 separate experiments: 1, 3, 5, and 7 kg/stall (experiment 2, n = 12) and 0.5, 1, 2, and 3 kg/stall (experiment 3, n = 12) were assessed. Treatments were compared using a crossover design with lactating cows housed in tie-stalls fitted with mattresses. Treatments were applied for 1 wk. Total lying time, number of lying bouts, and the length of each lying bout was recorded with data loggers. In experiment 1, cows spent 3 min more lying down for each additional kilogram of shavings (11.0, 11.7, 11.6, and 12.1 +/- 0.24 h/d for 3, 9, 15, and 24 kg/stall shavings, respectively). In experiment 2, cows increased lying time by 12 min for every additional kilogram of straw (11.2, 12.0, 11.8, and 12.4 +/- 0.24 h/d for 1, 3, 5, and 7 kg/stall of straw, respectively). There were no differences in lying behavior among the lower levels of straw tested in experiment 3 (11.7 +/- 0.32 h/d). These results indicated that additional bedding above a scant amount improves cow comfort, as measured by lying time, likely because a well-bedded surface is more compressible. PMID:19448001

  18. Automated manual transmission clutch controller

    DOEpatents

    Lawrie, Robert E. (9375 Kearney Rd., Whitmore Lake, MI 48189); Reed, Jr., Richard G. (3003 Bembridge, Royal Oak, MI 48073); Rausen, David J. (519 S. Gaylord St., Denver, CO 80209)

    1999-11-30

    A powertrain system for a hybrid vehicle. The hybrid vehicle includes a heat engine, such as a diesel engine, and an electric machine, which operates as both an electric motor and an alternator, to power the vehicle. The hybrid vehicle also includes a manual-style transmission configured to operate as an automatic transmission from the perspective of the driver. The engine and the electric machine drive an input shaft which in turn drives an output shaft of the transmission. In addition to driving the transmission, the electric machine regulates the speed of the input shaft in order to synchronize the input shaft during either an upshift or downshift of the transmission by either decreasing or increasing the speed of the input shaft. When decreasing the speed of the input shaft, the electric motor functions as an alternator to produce electrical energy which may be stored by a storage device. Operation of the transmission is controlled by a transmission controller which receives input signals and generates output signals to control shift and clutch motors to effect smooth launch, upshift shifts, and downshifts of the transmission, so that the transmission functions substantially as an automatic transmission from the perspective of the driver, while internally substantially functioning as a manual transmission.

  19. Transmission speed sensor arrangement

    SciTech Connect

    Nogle, T.D.

    1986-05-06

    In an engine driven vehicle having an engine extending transversely with respect to the vehicle at one end thereof, a pair of wheels at the same end of the vehicle, and automatic drive transmission means connecting the engine to the wheels, the automatic drive transmission means includes a housing attached to the vehicle. The housing has a torque converter section, a speed change section adjacent the torque converter section, and a differential and transfer section; the engine having a crankshaft, a torque converter in the torque converter section of the housing rotatable on the same axis as the crankshaft and adapted to be driven by the engine crankshaft, the torque converter drivingly connected to one outer end of a transmission input shaft, the input shaft having its other inner end located about midway through the speed change section, a speed change section output shaft mounted coaxial with the input shaft in the speed change section with its inner end adjacent the input shaft inner end and its outer free end extending beyond the speed change section, an output gear having peripheral teeth formed thereon, the output gear connected on the output shaft outer free end such that the output shaft and the output gear rotate on the input shaft axis, a transfer shaft having a transfer gear engaged with the output gear, the output shaft having a bore extending axially therethrough, the improvement wherein; a speed sensor shaft having a speed sensor wheel with peripheral teeth formed thereon fixed on the free outer end thereof, means journally supporting the speed shaft concentrically within the output shaft bore such that the speed wheel is axially spaced closely adjacent to the output gear.

  20. Planetary Transmission Diagnostics

    NASA Technical Reports Server (NTRS)

    Lewicki, David G. (Technical Monitor); Samuel, Paul D.; Conroy, Joseph K.; Pines, Darryll J.

    2004-01-01

    This report presents a methodology for detecting and diagnosing gear faults in the planetary stage of a helicopter transmission. This diagnostic technique is based on the constrained adaptive lifting algorithm. The lifting scheme, developed by Wim Sweldens of Bell Labs, is a time domain, prediction-error realization of the wavelet transform that allows for greater flexibility in the construction of wavelet bases. Classic lifting analyzes a given signal using wavelets derived from a single fundamental basis function. A number of researchers have proposed techniques for adding adaptivity to the lifting scheme, allowing the transform to choose from a set of fundamental bases the basis that best fits the signal. This characteristic is desirable for gear diagnostics as it allows the technique to tailor itself to a specific transmission by selecting a set of wavelets that best represent vibration signals obtained while the gearbox is operating under healthy-state conditions. However, constraints on certain basis characteristics are necessary to enhance the detection of local wave-form changes caused by certain types of gear damage. The proposed methodology analyzes individual tooth-mesh waveforms from a healthy-state gearbox vibration signal that was generated using the vibration separation (synchronous signal-averaging) algorithm. Each waveform is separated into analysis domains using zeros of its slope and curvature. The bases selected in each analysis domain are chosen to minimize the prediction error, and constrained to have the same-sign local slope and curvature as the original signal. The resulting set of bases is used to analyze future-state vibration signals and the lifting prediction error is inspected. The constraints allow the transform to effectively adapt to global amplitude changes, yielding small prediction errors. However, local wave-form changes associated with certain types of gear damage are poorly adapted, causing a significant change in the prediction error. The constrained adaptive lifting diagnostic algorithm is validated using data collected from the University of Maryland Transmission Test Rig and the results are discussed.

  1. Dynamically prioritized progressive transmission

    NASA Astrophysics Data System (ADS)

    Blanford, Ronald

    1992-04-01

    Retrieval of image data from a centralized database may be subject to bandwidth limitations, whether due to a low-bandwidth communications link or to contention from simultaneous accesses over a high-bandwidth link. Progressive transmission can alleviate this problem by encoding image data so that any prefix of the data stream approximates the complete image at a coarse level of resolution. The longer the prefix, the finer the resolution. In many cases, as little at 1 percent of the image data may be sufficient to decide whether to discard the image, to permit the retrieval to continue, or to restrict retrieval to a subsection of the image. Our approach treats resolution not as a fixed attribute of the image, but rather as a resource which may be allocated to portions of the image at the direction of a user-specified priority function. The default priority function minimizes error by allocating more resolution to regions of high variance. The user may also point to regions of interest requesting priority transmission. More advanced target recognition strategies may be incorporated at the user's discretion. Multispectral imagery is supported. The user engineering implications are profounded. There is immediate response to a query that might otherwise take minutes to complete. The data is transmitted in small increments so that no single user dominates the communications bandwidth. The user-directed improvement means that bandwidth is focused on interesting information. The user may continue working with the first coarse approximations while further image data is still arriving. The algorithm has been implemented in C on Sun, Silicon Graphics, and NeXT workstations, and in Lisp on a Symbolics. Transmission speeds reach as high as 60,000 baud using a Sparc or 68040 processor when storing data to memory; somewhat less if also updating a graphical display. The memory requirements are roughly five bytes per image pixel. Both computational and memory costs may be reduced by increasing the time between priority computations. Progressive transmission improves the performance of lossless LZW or Huffman compression. If exact reconstruction of the image is not needed, the transmitted values may be quantized to achieve further compression. Our experience shows the technique to be flexible enough to support a variety of situations.

  2. Block-based Bitrate Control for Wireless Networks Xiaozheng Tie, Anand Seetharam, Arun Venkataramani, Deepak Ganesan, Dennis L. Goeckel

    E-print Network

    Venkataramani, Arun

    Block-based Bitrate Control for Wireless Networks Xiaozheng Tie, Anand Seetharam, Arun present BlockRate, a wireless bitrate adaptation algorithm designed for blocks, or large con- tiguous that can either have the amortization benefits of blocks or high responsiveness to underlying channel

  3. EFL Doctoral Students' Conceptions of Authorial Stance in Academic Knowledge Claims and the Tie to Epistemic Beliefs

    ERIC Educational Resources Information Center

    Chang, Peichin; Tsai, Chin-Chung

    2014-01-01

    Taking an effective authorial stance in research argumentation has been designated as both vitally important and challenging. The study investigated English as a foreign language (EFL) doctoral students' conceptions of authorial stance, the role of domains in affecting their conceptions, and the ties of the conceptions to the…

  4. Will Economic Crises in Africa Weaken Rural-Urban Ties? Insights from Child Fosterage Trends in Cameroon.

    ERIC Educational Resources Information Center

    Eloundou-Enyegue, Parfait M.; Stokes, C. Shannon

    2002-01-01

    In many African countries, rural-urban kinship ties support the education and economic mobility of rural children through fosterage into urban families. Demographic survey data from central Cameroon indicate major rural-urban differences in child fosterage relative to family characteristics and child's school performance, and show lower rural…

  5. Social networks of experientially similar others: formation, activation, and consequences of network ties on the health care experience.

    PubMed

    Gage, Elizabeth A

    2013-10-01

    Research documents that interactions among experientially similar others (individuals facing a common stressor) shape health care behavior and ultimately health outcomes. However, we have little understanding of how ties among experientially similar others are formed, what resources and information flows through these networks, and how network embeddedness shapes health care behavior. This paper uses in-depth interviews with 76 parents of pediatric cancer patients to examine network ties among experientially similar others after a serious medical diagnosis. Interviews were conducted between August 2009 and May 2011. Findings demonstrate that many parents formed ties with other families experiencing pediatric cancer, and that information and resources were exchanged during the everyday activities associated with their child's care. Network flows contained emotional support, caregiving strategies, information about second opinions, health-related knowledge, and strategies for navigating the health care system. Diffusion of information, resources, and support occurred through explicit processes (direct information and support exchanges) and implicit processes (parents learning through observing other families). Network flows among parents shaped parents' perceptions of the health care experience and their role in their child's care. These findings contribute to the social networks and social support literatures by elucidating the mechanisms through which network ties among experientially similar others influence health care behavior and experiences. PMID:22999229

  6. Nonequilibrium and current sheet formation in line-tied magnetic fields C. S. Ng and A. Bhattacharjee

    E-print Network

    Ng, Chung-Sang

    Nonequilibrium and current sheet formation in line-tied magnetic fields C. S. Ng and A to, and the system tends to a nonequilibrium state containing singular currents ``current sheets possibly in infinite time . Numerical simulations that begin from smooth initial conditions containing

  7. Activated Protein C Enhances Human Keratinocyte Barrier Integrity via Sequential Activation of Epidermal Growth Factor Receptor and Tie2*

    PubMed Central

    Xue, Meilang; Chow, Shu-Oi; Dervish, Suat; Chan, Yee-Ka Agnes; Julovi, Sohel M.; Jackson, Christopher J.

    2011-01-01

    Keratinocytes play a critical role in maintaining epidermal barrier function. Activated protein C (APC), a natural anticoagulant with anti-inflammatory and endothelial barrier protective properties, significantly increased the barrier impedance of keratinocyte monolayers, measured by electric cell substrate impedance sensing and FITC-dextran flux. In response to APC, Tie2, a tyrosine kinase receptor, was rapidly activated within 30 min, and relocated to cell-cell contacts. APC also increased junction proteins zona occludens, claudin-1 and VE-cadherin. Inhibition of Tie2 by its peptide inhibitor or small interfering RNA abolished the barrier protective effect of APC. Interestingly, APC did not activate Tie2 through its major ligand, angiopoietin-1, but instead acted by binding to endothelial protein C receptor, cleaving protease-activated receptor-1 and transactivating EGF receptor. Furthermore, when activation of Akt, but not ERK, was inhibited, the barrier protective effect of APC on keratinocytes was abolished. Thus, APC activates Tie2, via a mechanism requiring, in sequential order, the receptors, endothelial protein C receptor, protease-activated receptor-1, and EGF receptor, which selectively enhances the PI3K/Akt signaling to enhance junctional complexes and reduce keratinocyte permeability. PMID:21173154

  8. Keratinocyte but Not Endothelial Cell-Specific Overexpression of Tie2 Leads to the Development of Psoriasis

    PubMed Central

    Wolfram, Julie A.; Diaconu, Doina; Hatala, Denise A.; Rastegar, Jessica; Knutsen, Dorothy A.; Lowther, Abigail; Askew, David; Gilliam, Anita C.; McCormick, Thomas S.; Ward, Nicole L.

    2009-01-01

    Psoriasis is initiated and maintained through a multifaceted interplay between keratinocytes, blood vessels, gene expression, and the immune system. One previous psoriasis model demonstrated that overexpression of the angiopoietin receptor Tie2 in endothelial cells and keratinocytes led to the development of a psoriasiform phenotype; however, the etiological significance of overexpression in each cell type alone was unclear. We have now engineered two new mouse models whereby Tie2 expression is confined to either endothelial cells or keratinocytes. Both lines of mice have significant increases in dermal vasculature but only the KC-Tie2-overexpressing mice developed a cutaneous psoriasiform phenotype. These mice spontaneously developed characteristic hallmarks of human psoriasis, including extensive acanthosis, increases in dermal CD4+ T cells, infiltrating epidermal CD8+ T cells, dermal dendritic cells and macrophages, and increased expression of cytokines and chemokines associated with psoriasis, including interferon-?, tumor necrosis factor-?, and interleukins 1?, 6, 12, 22, 23, and 17. Host-defense molecules, cathelicidin, ?-defensin, and S100A8/A9, were also up-regulated in the hyperproliferative skin. All of the phenotypic traits were completely reversed without any scarring following repression of the transgene and were significantly improved following treatment with the anti-psoriasis systemic therapeutic, cyclosporin A. Therefore, confining Tie2 overexpression solely to keratinocytes results in a mouse model that meets the clinical, histological, immunophenotypic, biochemical, and pharmacological criteria required for an animal model of human psoriasis. PMID:19342373

  9. From the Cotton Fields to the Ties That Bind: Jim Pusack's Enduring Impact on Today's CALL Development

    ERIC Educational Resources Information Center

    Jones, Linda C.

    2010-01-01

    From 1981 to today, the encouragement Jim Pusack and his colleague Sue Otto gave faculty to develop and/or implement CALL into the curriculum has been vital to our L2 teaching evolution. This article describes how their efforts evolved over the last two and a half decades and the ties that bind their efforts with today's CALL development.

  10. GISS 2007 Temperature Analysis The year 2007 tied for second warmest in the period of instrumental data, behind the

    E-print Network

    Hansen, James E.

    . 2007 tied 1998, which had leapt a remarkable 0.2°C above the prior record with the help of the "El Nino is at a minimum and the equatorial Pacific Ocean is in the cool phase of its natural El Nino ­ La Nina cycle low Arctic sea ice cover in September 2007. El Nino-La Nina Cycle. The cooler than normal equatorial

  11. Family Ties and Health Cross-Nationally: The Contextualizing Role of Familistic Culture and Public Pension Spending in Europe

    PubMed Central

    2013-01-01

    Objectives. Although previous research theorizes that cross-national variation in the relationship between family ties and health is due to nation-level differences in culture and policy/economics, no study has examined this theorization empirically. Method. Using data from the Survey of Health, Ageing, and Retirement in Europe (SHARE) and the Organization for Economic Co-operation and Development (OECD), this study uses multilevel modeling to analyze individual-, nation-, and cross-level effects for 30,291 older adults in 14 nations. Results. Family ties to spouses/partners and parents are associated with better health, but ties to coresident children are associated with poorer health in certain contexts. Familistic culture and public pension spending have a weak but statistically significant moderating effect on the relationship between intergenerational family ties and health. Discussion. This article underscores the complexity of family and highlights the need for continued theorization and measurement at the nation level to promote older adults’ health in diverse contexts. PMID:24043356

  12. 49 CFR 1242.15 - Roadway, tunnels and subways, bridges and culverts, ties, rails, other track material, ballast...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Roadway, tunnels and subways, bridges and culverts, ties, rails, other track material, ballast, track laying and surfacing, and road property damaged... RAILROADS 1 Operating Expenses-Way and Structures § 1242.15 Roadway, tunnels and subways, bridges...

  13. Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2

    PubMed Central

    Wu, Florence TH; Lee, Christina R; Bogdanovic, Elena; Prodeus, Aaron; Gariépy, Jean; Kerbel, Robert S

    2015-01-01

    Angiopoietin-1 (Ang1) activation of Tie2 receptors on endothelial cells (ECs) reduces adhesion by tumor cells (TCs) and limits junctional permeability to TC diapedesis. We hypothesized that systemic therapy with Vasculotide (VT)—a purported Ang1 mimetic, Tie2 agonist—can reduce the extravasation of potentially metastatic circulating TCs by similarly stabilizing the host vasculature. In vitro, VT and Ang1 treatments impeded endothelial hypermeability and the transendothelial migration of MDA-MB-231•LM2-4 (breast), HT29 (colon), or SN12 (renal) cancer cells to varying degrees. In mice, VT treatment inhibited the transit of TCs through the pulmonary endothelium, but not the hepatic or lymphatic endothelium. In the in vivo LM2-4 model, VT monotherapy had no effect on primary tumors, but significantly delayed distant metastatic dissemination to the lungs. In the post-surgical adjuvant treatment setting, VT therapeutically complemented sunitinib therapy, an anti-angiogenic tyrosine kinase inhibitor which limited the local growth of residual disease. Unexpectedly, detailed investigations into the putative mechanism of action of VT revealed no evidence of Tie2 agonism or Tie2 binding; alternative mechanisms have yet to be determined. PMID:25851538

  14. 30 CFR 585.223 - What does BOEM do if there is a tie for the highest bid?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What does BOEM do if there is a tie for the highest bid? 585.223 Section 585.223 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable...

  15. 77 FR 52352 - Notice of Intent To Prepare an Environmental Impact Statement for the Rio Mesa Gen-Tie Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-29

    ... Gen-Tie Project and Possible Land Use Plan Amendment, Riverside County, CA AGENCY: Bureau of Land..., special management areas, land use, noise, paleontological resources, public health, socioeconomic, soils.... If a land use plan amendment is necessary, the BLM will integrate the land use planning process...

  16. UConn Extension App Challenge The UConn Extension App Challenge is a contest to develop innovative apps that tie

    E-print Network

    Demurjian, Steven A.

    UConn Extension App Challenge The UConn Extension App Challenge is a contest to develop innovative apps that tie UConn's research to real life. Students are invited to work with a UConn Extension innovative and effective apps Student Prizes: 1st Place: $1500 2nd Place: $1000 3rd Place: $500 Winners

  17. Ranking Websites, a Probabilistic View Ying Bao, Gang Feng, Tie-Yan Liu, Zhi-Ming Ma, and Ying Wang

    E-print Network

    Ma, Zhi-Ming

    Ranking Websites, a Probabilistic View Ying Bao, Gang Feng, Tie-Yan Liu, Zhi-Ming Ma, and Ying Wang Abstract In this paper we suggest evaluating the importance of a website with the mean fre- quency of visiting the website for the Markov chain on the Internet Graph describing random surfing. We show

  18. Wildfire risk transmission in the Colorado Front Range, USA.

    PubMed

    Haas, Jessica R; Calkin, David E; Thompson, Matthew P

    2015-02-01

    Wildfires are a global phenomenon that in some circumstances can result in human casualties, economic loss, and ecosystem service degradation. In this article we spatially identify wildfire risk transmission pathways and locate the areas of highest exposure of human populations to wildland fires under severe, but not uncommon, weather events. We quantify varying levels of exposure in terms of population potentially affected and tie the exposure back to the spatial source of the risk for the Front Range of Colorado, USA. We use probabilistic fire simulation modeling to address where fire ignitions are most likely to cause the highest impact to human communities, and to explore the role that various landowners play in that transmission of risk. Our results indicated that, given an ignition and the right fire weather conditions, large areas along the Front Range in Colorado could be exposed to wildfires with high potential to impact human populations, and that overall private ignitions have the potential to impact more people than federal ignitions. These results can be used to identify high-priority areas for wildfire risk mitigation using various mitigation tools. PMID:25156542

  19. Small passenger car transmission test-Chevrolet 200 transmission

    NASA Technical Reports Server (NTRS)

    Bujold, M. P.

    1980-01-01

    The small passenger car transmission was tested to supply electric vehicle manufacturers with technical information regarding the performance of commerically available transmissions which would enable them to design a more energy efficient vehicle. With this information the manufacturers could estimate vehicle driving range as well as speed and torque requirements for specific road load performance characteristics. A 1979 Chevrolet Model 200 automatic transmission was tested per a passenger car automatic transmission test code (SAE J651b) which required drive performance, coast performance, and no load test conditions. The transmission attained maximum efficiencies in the mid-eighty percent range for both drive performance tests and coast performance tests. Torque, speed and efficiency curves map the complete performance characteristics for Chevrolet Model 200 transmission.

  20. Small passenger car transmission test: Mercury Lynx ATX transmission

    SciTech Connect

    Bujold, M P

    1981-09-01

    The small passenger car transmission test was initiated to supply electric vehicle manufacturers with technical information regarding the performance of commercially available transmissions. This information would enable EV manufacturers to design a more energy efficient vehicle. With this information the manufacturers would be able to estimate vehicle driving range as well as speed and torque requirements for specific road load performance characteristics. This report covers the 1981 Mercury Lynx ATX transaxle. This transmission was tested per a passenger car automatic transmission test code (SAE J65lb) which required drive performance, coast performance, and no load test conditions. Under these test conditions the transmission attained maximum efficiencies in the 93% range for drive performance tests. The major results of this test are the torque, speed and efficiency curves which are located in the data section of this report. These graphs map performance characteristics for the Mercury Lynx ATX transmission.

  1. Simplified power shift transmission

    SciTech Connect

    Michael, R.A.

    1987-04-21

    A multi-speed transmission is described for transferring power between a first shaft and a second shaft, the transmission comprising: a compound planetary assembly including a sun gear, a ring gear concentric with the sun gear, a reaction gear concentric with the ring gear, a planetary gear carrier rotatably supporting first and second sets of planet gears, the first planet gear set intermeshing with the ring gear. The sun gear and the second planet gear set intermesh with the first planet gear set and the reaction gear, means for selectively coupling the first shaft with the sun gear and the reaction gear, and means for selectively preventing rotation of the ring gear, and reaction gear and the planetary carrier; a simple planetary assembly comprising a sun gear component concentric with the sun gear of the compound planetary assembly, a ring gear component concentric with both of the sun gears, and a planetary gear carrier component rotatably supporting a set of planet gears, the planet gear set meshing with the sun gear and the ring gear of the simple planetary.

  2. Transmission shift mechanism

    SciTech Connect

    Smith, R.R.

    1989-06-20

    This patent describes a mechanism for selecting the gear of an automatic transmission in a vehicle. The mechanism consists of: a pressure source; a gear selection valve having an inlet means for receiving fluid from the pressure source, first outlet ports, and second outlet ports; a manual override means for opening and blocking communication between the pressure source and the first ports and for simultaneously opening and blocking communication between the pressure source and the second outlet ports; a port selector means within the valve for controlling flow through the second ports, the port selector means being movable to a plurality of positions, each position permitting a selected second outlet port to open; a selector control mans for moving the port selector means from one position to another, the selector control means including a planetary gear set connected by an input shaft to the transmission and connected to a vehicle load by an output shaft, the planetary gear set having a ring gear whose angular position is a function of reaction torque imposed by the load on the output shaft, the selector control means further including an arm assembly connected between the ring gear and the port selector means so that the position of the port selector means is a function of the reaction torque on the output shaft.

  3. Colorado Electrical Transmission Grid

    SciTech Connect

    Zehner, Richard E.

    2012-02-01

    Citation Information: Originator: Earth Science &Observation Center (ESOC), CIRES, University of Colorado at Boulder Originator: Xcel Energy Publication Date: 2012 Title: Colorado XcelEnergy NonXcel Transmission Network Edition: First Publication Information: Publication Place: Earth Science & Observation Center, Cooperative Institute for Research in Environmental Science (CIRES), University of Colorado, Boulder Publisher: Earth Science &Observation Center (ESOC), CIRES, University of Colorado at Boulder Description: This layer contains transmission network of Colorado Spatial Domain: Extent: Top: 4540689.017558 m Left: 160606.141934 m Right: 758715.946645 m Bottom: 4098910.893397m Contact Information: Contact Organization: Earth Science &Observation Center (ESOC), CIRES, University of Colorado at Boulder Contact Person: Khalid Hussein Address: CIRES, Ekeley Building Earth Science & Observation Center (ESOC) 216 UCB City: Boulder State: CO Postal Code: 80309-0216 Country: USA Contact Telephone: 303-492-6782 Spatial Reference Information: Coordinate System: Universal Transverse Mercator (UTM) WGS’1984 Zone 13N False Easting: 500000.00000000 False Northing: 0.00000000 Central Meridian: -105.00000000 Scale Factor: 0.99960000 Latitude of Origin: 0.00000000 Linear Unit: Meter Datum: World Geodetic System ’1984 (WGS ’1984) Prime Meridian: Greenwich Angular Unit: Degree Digital Form: Format Name: Shapefile

  4. Transmission shift control assembly

    SciTech Connect

    Dzioba, D.L.

    1989-04-18

    This patent describes a transmission shift control assembly mounted on a steering column having a longitudinal axis comprising: bracket means secured to the steering column; transmission shift cable means having a portion secured to the bracket means and a portion linearly movable relative to the secured portion; mounting means on the bracket cable drive arm means having an axis and being rotatably mounted on the rotary axis on the mounting means oblique to the longitudinal axis and including a cable connecting portion secured to the movable portion of the cable means and lever mounting means adjacent the mounting means; operator control means including lever means, pin means for pivotally mounting the lever means on the lever mounting means on an axis substantially perpendicular to the rotary axis and positioning arm means formed on the lever means and extending from the pin means; and detent gate means disposed on the bracket means in position to abut the positioning arm means for limiting the extent of pivotal movement of the lever means.

  5. Laboratory study of the equilibrium and eruption of line-tied magnetic flux ropes in the solar corona

    NASA Astrophysics Data System (ADS)

    Myers, Clayton Edward

    2015-03-01

    Ideal magnetohydrodynamic (MHD) instabilities such as the kink instability and the torus instability are leading candidates to explain the sudden onset of eruptive events in the solar corona. These instabilities act on line-tied magnetic flux ropes--long-lived arched structures anchored to the solar surface. In spite of substantial observational and numerical research, however, the role of these instabilities in the corona remains a subject of intense debate. For this thesis, we have constructed and operated a new line-tied flux rope experiment that permits for the first time the study of both the kink and torus instabilities in the laboratory. This experiment has the following key features: (1) the arched flux rope is line-tied to two conducting footpoints; (2) the system is magnetically dominated (low-beta) with significant stored energy; (3) the system is driven quasi-statically, producing a long-lived equilibrium; and (4) the flux rope is generated within a potential (vacuum) magnetic field arcade whose decay index---the predicted torus instability control parameter---can be externally controlled. The flux ropes are diagnosed using a two-dimensional in situ magnetic probe array whose cross-section covers a substantial portion of the plasma. The central result of this thesis is that toroidal field forces, which are traditionally neglected in the analysis of coronal flux ropes, are identified for the first time as an essential contributor to both the equilibrium and the stability of line-tied flux ropes. Most importantly, experimental measurements show that a tension force derived from a self-generated paramagnetic toroidal field exerts a restoring force on the line-tied plasma and suppresses eruptive behavior in a significant portion of the parameter space. This suppression extends to regimes that are both kink and torus unstable. We find that, in order to explain the measured tension force, low aspect ratio and line-tying effects must be considered. Finally, flux rope eruptions are observed in these experiments, but only in regimes with sufficiently low external toroidal field where the tension force is reduced. These results constitute a new condition for the prediction of line-tied magnetic flux rope eruptions: that of low external toroidal field.

  6. The Strength of Strong Ties for Older Rural Adults: Regional Distinctions in the Relationship between Social Interaction and Subjective Well-Being

    ERIC Educational Resources Information Center

    Mair, Christine A.; Thivierge-Rikard, R. V.

    2010-01-01

    Classic and contemporary sociological theories suggest that social interaction differs in rural and urban areas. Intimate, informal interactions (strong ties) are theorized to characterize rural areas while urban areas may possess more formal and rationalized interactions (weak ties). Aging and social support literature stresses social interaction…

  7. Multi-Omics Classification of Head and Neck Cancer Ties TP53 Mutation To 3p Loss - Andrew M. Gross, TCGA Scientific Symposium 2014

    Cancer.gov

    Home News and Events Multimedia Library Videos Multi-Omics Classification of Head and Neck Cancer Ties TP53 Mutation To 3p Loss - Andrew M. Gross Multi-Omics Classification of Head and Neck Cancer Ties TP53 Mutation To 3p Loss - Andrew M. Gross,

  8. Depletion of antigen presenting cells by clodronate liposomes reverses the psoriatic skin phenotype in KC-Tie2 mice

    PubMed Central

    Ward, N. L.; Loyd, C. M.; Wolfram, J.A.; Diaconu, D.; Michaels, C. M.; McCormick, T. S.

    2010-01-01

    Summary Background There is ongoing debate regarding the initiation of psoriatic plaque as primarily arising from an anomaly in epidermal keratinocytes (KCs) or from abnormalities in immunocytes that secondarily activate otherwise normal KCs. In mice engineered to overexpress the angiopoietin receptor Tie2 in KCs, skin spontaneously develops the characteristic clinical, histological and immune cell phenotypes of psoriasis which can be reversed with either transgene repression or cyclosporin A administration, suggesting key roles for both KCs and T cells in mediating the skin disease in this murine model. Objectives To determine if antigen presenting cells and macrophages alone are sufficient to sustain psoriasiform inflammation in the KC-Tie2 murine model of psoriasis. Methods Clodronate liposomes were intradermally injected into involved dorsal skin of KC-Tie2 or control animals once a week for 6 weeks and acanthosis, angiogenesis, immune cell infiltration and cytokine production was quantitated using immunohistochemistry and interactive image analyses, enzyme linked immunosorbant assay (ELISAs) and quantitative real-time polymerase chain reaction (qRT-PCR). Results Clodronate liposome injection eliminated CD11c+, F4/80+, and CD11b+ cells in the skin and returned CD8+ T cell numbers to control mouse levels. Antigen presenting cell depletion in KC-Tie2 mouse skin resulted in resolution of the acanthotic skin phenotype, decreased dermal angiogenesis, and a return to control mouse levels for IL-1?, IL-6, IL-23 and TNF? expression and modest reductions in IFN? and IL-17. Conclusions These findings suggest a critical role for APCs and myeloid cell derived IL-23 and TNF? and underscore the importance of Th1 and Th17 T cells in maintaining the psoriasiform skin phenotype in the KC-Tie2 mouse model. PMID:21070202

  9. Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass

    PubMed Central

    Jongman, Rianne M.; van Klarenbosch, Jan; Molema, Grietje; Zijlstra, Jan G.

    2015-01-01

    Introduction The pathophysiology of acute kidney injury (AKI) after cardiac surgery is not completely understood. Recent evidence suggests a pivotal role for the endothelium in AKI. In experimental models of AKI, the endothelial specific receptor Tie2 with its ligands Angiopoietin (Ang) 1 and Ang2 are deranged. This study investigates their status after cardiac surgery, and a possible relation between angiopoietins and AKI. Methods From a cohort of 541 patients that underwent cardiac surgery, blood and urine was collected at 5 predefined time points. From this cohort we identified 21 patients who had at least 50% post-operative serum creatinine increase (AKI). We constructed a control group (n = 21) using propensity matching. Systemic levels of Ang1, Ang2, and sTie2 were measured in plasma and the AKI markers albumin, kidney injury molecule-1 (KIM-1) and N-acetyl-beta-D-glucosaminidase (NAG) were measured in the urine. Results Ang2 plasma levels increased over time in AKI (from 4.2 to 11.6 ng/ml) and control patients (from 3.0 to 6.7 ng/ml). Ang2 levels increased 1.7-fold more in patients who developed AKI after cardiac surgery compared to matched control patients. Plasma levels of sTie2 decreased 1.6-fold and Ang1 decreased 3-fold over time in both groups, but were not different between AKI and controls (Ang1 P = 0.583 and sTie2 P = 0.679). Moreover, we found a positive correlation between plasma levels of Ang2 and urinary levels of NAG. Conclusions The endothelial Ang/Tie2 system is in dysbalance in patients that develop AKI after cardiac surgery compared to matched control patients. PMID:26309217

  10. Development of circumferential seal for helicopter transmissions: Results of bench and flight tests

    NASA Technical Reports Server (NTRS)

    Strom, T. N.; Ludwig, L. P.

    1975-01-01

    A modified circumferential segmented ring seal was designed for direct replacement of a helicopter transmission elastomeric lip seal operating on a shaft diameter of 13.91 centimeters (5.481 in.) at sliding velocities to 52.48 m/sec (10 330 ft/min). The modifications involved the garter spring tension, shaft roundness, seal housing flatness, and pumping grooves to inhibit leakage. Operation of the seals in bench tests under simulated helicopter transmission conditions revealed that the seal leakage rate was within acceptable limits and that the wear rate was negligible. The low leakage and wear rates were confirmed in flight tests of 600 and 175 hours (sliding speed, 48.11 m/sec (9470 ft/min)). An additional 200 hours of air worthiness qualification testing (aircraft tie down) demonstrated that the seal can operate at the advanced sliding conditions of 52.48 m/sec (10 330 ft/min).

  11. Regional Seismic Architecture Tied to Cores: Results from IODP Exp313

    NASA Astrophysics Data System (ADS)

    Mountain, G.; Proust, J.; Monteverde, D.; Scienceparty, E.

    2010-12-01

    Siliciclastic sediments at passive margins contain stratal discontinuities at many scales; most can be imaged in seismic profiles. Regional unconformities associated with lowering of baselevel (‘sequence boundaries’) are of special importance because they provide the means to objectively divide the stratigraphic record, and intervening sequences provide the basis for evaluating controls on facies successions and overall sedimentary architecture. Furthermore, sequences of similar age and shape at margins of contrasting tectonic and sedimentary histories suggest eustatic control, though this needs to be tested. IODP Exp313 was designed to contribute to such a test by determining the age and facies of sediments cored at several locations within mid-Tertiary sequences ~45-65 km offshore New Jersey. The reliability of seismic-core correlations essential to this effort required high core recovery, high resolution seismic data, and techniques for matching the two; here we report progress in this effort. Three holes were drilled and logged in ~35 m of water in May-July 2009. Roughly 9500 km of profiles were examined and correlated to these and 6 additional sites drilled previously on the outer shelf and upper slope. 13 additional holes drilled into correlative sediments on the adjacent coastal plain provided up-dip facies and age control, though onshore seismic data are lacking. Prior studies identified seismic sequence boundaries at the NJ margin on the basis of seismic onlap/offlap and ties to drill cores on the continental slope. 15 regionally mapped reflectors intersect the Exp313 sites, and as a first step in tying each to a feature in a core, stacking velocities from the processing of seismic data passing through Exp313 sites were used to derive an acoustic travel time to depth-below-seafloor conversion. This relationship provided expectations of depths at which surfaces and/or facies changes would be found. Typically these occur within 5-10 m of a probable match to features in the cores or to various properties measured by wireline logs and/or the Multi-Sensor Core Logger. Within clinoform top-set beds these reflectors often match transgressive or regressive facies and an accompanying change in density over a depth of 10 cm or less. Finer toe-set strata seaward of clinoform slopes contain beds of gravity-transported sediment where again abrupt changes in bulk density is a typical cause of acoustic reflections. A previously mapped 500 km2 seismic surface ties to the deeply eroded core of a clinoform buildup that failed locally and was redeposited in mass-flow deposits 10's of km seaward of its original location; that it can be traced elsewhere to an intact deposit underscores the importance of along-strike mapping that guards against hasty conclusions of eustatic influence. Facies changes separated by less than 5 m are difficult to link to one in a group of closely-spaced reflectors. Physical properties measured in core material or derived from wireline logs will be used in the future to develop synthetic seismograms and refine core-log-seismic correlations further.

  12. Technology of optical azimuth transmission

    NASA Astrophysics Data System (ADS)

    Lu, Honggang; Hu, Chunsheng; Wang, Xingshu; Gao, Yang

    2012-11-01

    It often needs transfer a reference from one place to another place in aerospace and guided missile launching. At first, principles of several typical optical azimuth transmission methods are presented. Several typical methods are introduced, such as Theodolite (including gyro-theodolite) collimation method, Camera series method, Optical apparatus for azimuth method and polarization modulated light transmission method. For these typical azimuth transmission methods, their essential theories are elaborated. Then the devices, the application fields and limitations of these typical methods' are presented. Theodolite (including gyro-theodolite) collimation method is used in the ground assembly of spacecraft. Camera series method and optical apparatus for azimuth method are used in azimuth transmission between different decks of ship. Polarization modulated light transmission method is used in azimuth transmission of rocket and guided missile. At the last, the further developments of these methods are discussed.

  13. Quality resource networks for young women in science: The role of Internet-facilitated ties

    NASA Astrophysics Data System (ADS)

    Gillette, Shana Cecile

    In communications, a new approach to the study of online interaction has been suggested by social network analysts. Garton, Haythornthwaite, and Wellman (1997) have outlined the importance of using network analysis to study how media are interconnected with other social aspects of a media user's world. As applied here, this approach to communication when combined with recent network studies from the fields of education and rural development, provides a method for looking at the role of Internet-facilitated ties in the development of resource networks in the learning communities of young women from seven rural schools across the state of Washington. Twenty-six young women (ages 14-16) from diverse cultural and ethnic backgrounds (approximately half of the participants are Hispanic or Native American, the other half are White) participated in the research. Participants were selected because they shared a common educational orientation through Rural Girls in Science, a NSF-funded program at the Northwest Center for Research on Women at the University of Washington. As part of the school-based component of the Rural Girls in Science program, all 26 participants designed and conducted year-long, community-based research projects in science. Each school in the program was provided an Internet workstation for communication and research. Through the Internet, students could conceivably maintain distant ties with mentors and research scientists whom they met at summer camp as well as seek additional information resources. Toward the conclusion of the long-term research projects, each student participant was interviewed using a participatory form of network analysis that included a combined qualitative and quantitative approach. Given the small number of participants and schools in the sample, the results from the analysis can not be generalized to a larger population. However the study of the structure and composition of networks among individuals and school groups provided insight into how media are implicated in the development of resource networks, in particular for a subset of students who have been underrepresented in science--young ethnic minority women.

  14. Transmission for a tractor

    SciTech Connect

    Takagi, M.; Watashi, M.

    1986-09-09

    A transmission for a tractor having front and rear wheels is described which consists of: an input shaft operatively connected to an engine; running-travel shaft means operatively connected between the input shaft and a rear wheel drive shaft for driving the rear wheels of the tractor, the running-travel shaft means including a main change speed means; PTO shaft means operatively connected to the input shaft and including a PTO counter shaft; a first gear rotatably mounted on the PTO counter shaft and operatively connected to the rear wheel drive shaft; front wheel drive shaft means disposed below the PTO counter shaft and including a second gear rotatably mounted thereon, the front wheel drive shaft means being adapted to be operatively connectable to the rear wheel drive shaft through the first gear; a mid-PTO shaft disposed below the front wheel drive shaft means and operatively connected to the PTO counter shaft through the second gear.

  15. Fiber optic data transmission

    NASA Technical Reports Server (NTRS)

    Shreve, Steven T.

    1987-01-01

    The Ohio University Avionics Engineering Center is currently developing a fiber optic data bus transmission and reception system that could eventually replace copper cable connections in airplanes. The original form of the system will transmit information from an encoder to a transponder via a fiber optic cable. An altimeter and an altitude display are connected to a fiber optic transmitter by copper cable. The transmitter converts the altimetry data from nine bit parallel to serial form and send these data through a fiber optic cable to a receiver. The receiver converts the data using a cable similar to that used between the altimeter and display. The transmitting and receiving ends also include a display readout. After completion and ground testing of the data bus, the system will be tested in an airborne environment.

  16. Dynamic Transmission Electron Microscopy

    SciTech Connect

    Evans, James E.; Jungjohann, K. L.; Browning, Nigel D.

    2012-10-12

    Dynamic transmission electron microscopy (DTEM) combines the benefits of high spatial resolution electron microscopy with the high temporal resolution of ultrafast lasers. The incorporation of these two components into a single instrument provides a perfect platform for in situ observations of material processes. However, previous DTEM applications have focused on observing structural changes occurring in samples exposed to high vacuum. Therefore, in order to expand the pump-probe experimental regime to more natural environmental conditions, in situ gas and liquid chambers must be coupled with Dynamic TEM. This chapter describes the current and future applications of in situ liquid DTEM to permit time-resolved atomic scale observations in an aqueous environment, Although this chapter focuses mostly on in situ liquid imaging, the same research potential exists for in situ gas experiments and the successful integration of these techniques promises new insights for understanding nanoparticle, catalyst and biological protein dynamics with unprecedented spatiotemporal resolution.

  17. Transmission seal development

    NASA Technical Reports Server (NTRS)

    Brien, M.

    1977-01-01

    An experimental evaluation was performed on a high-speed (72.9 m/s, 14,349 ft/min) transmission seal of the synergistic type. During testing of the seal, oil leakage occurred at positive bearing cavity pressures. Modifications were made in an attempt to eliminate the leakage but none were completely successful. Leakage appears to be the result of questionable positioning of the sealing elements resulting in inadequate shaft contact by the oil side sealing element. This condition may be related to the nonsymmetrical shape of the elastomeric retainer and to dimensional changes caused by swelling of the elastomeric retainer from exposure to the sealed fluid. Indications of a speed dependent leakage characteristic were also observed.

  18. Thrips transmission of tospoviruses.

    PubMed

    Rotenberg, Dorith; Jacobson, Alana L; Schneweis, Derek J; Whitfield, Anna E

    2015-12-01

    One hundred years ago, the disease tomato spotted wilt was first described in Australia. Since that time, knowledge of this disease caused by Tomato spotted wilt virus (TSWV) and transmitted by thrips (insects in the order Thysanoptera) has revealed a complex relationship between the virus, vector, plant host, and environment. Numerous tospoviruses and thrips vectors have been described, revealing diversity in plant host range and geographical distributions. Advances in characterization of the tripartite interaction between the virus, vector, and plant host have provided insight into molecular and ecological relationships. Comparison to animal-infecting viruses in the family Bunyaviridae has enabled the identification of commonalities between tospoviruses and other bunyaviruses in transmission by arthropod vectors and molecular interactions with hosts. This review provides a special emphasis on TSWV and Frankliniella occidentalis, the model tospovirus-thrips pathosystem. However, other virus-vector combinations are also of importance and where possible, comparisons are made between different viruses and thrips vectors. PMID:26340723

  19. Broadband Transmission EPR Spectroscopy

    PubMed Central

    Hagen, Wilfred R.

    2013-01-01

    EPR spectroscopy employs a resonator operating at a single microwave frequency and phase-sensitive detection using modulation of the magnetic field. The X-band spectrometer is the general standard with a frequency in the 9–10 GHz range. Most (bio)molecular EPR spectra are determined by a combination of the frequency-dependent electronic Zeeman interaction and a number of frequency-independent interactions, notably, electron spin – nuclear spin interactions and electron spin – electron spin interactions, and unambiguous analysis requires data collection at different frequencies. Extant and long-standing practice is to use a different spectrometer for each frequency. We explore the alternative of replacing the narrow-band source plus single-mode resonator with a continuously tunable microwave source plus a non-resonant coaxial transmission cell in an unmodulated external field. Our source is an arbitrary wave digital signal generator producing an amplitude-modulated sinusoidal microwave in combination with a broadband amplifier for 0.8–2.7 GHz. Theory is developed for coaxial transmission with EPR detection as a function of cell dimensions and materials. We explore examples of a doublet system, a high-spin system, and an integer-spin system. Long, straigth, helical, and helico-toroidal cells are developed and tested with dilute aqueous solutions of spin label hydroxy-tempo. A detection limit of circa 5 µM HO-tempo in water at 800 MHz is obtained for the present setup, and possibilities for future improvement are discussed. PMID:23555819

  20. TRANSMISSION MEDIA 4.1 Guided Transmission Media

    E-print Network

    Scarano, Vittorio

    microphones Microwave Radar Microwave antennas Magnetrons Infrared Lasers Guided missiles Rangefinders RadioCHAPTER 4 TRANSMISSION MEDIA 4.1 Guided Transmission Media Twisted Pair Coaxial Cable Optical Fiber information can be classi- fied as guided or unguided. Guided media provide a physical path along which

  1. The interior transmission problem and bounds on transmission eigenvalues

    E-print Network

    Michael Hitrik; Katsiaryna Krupchyk; Petri Ola; Lassi Päivärinta

    2010-09-28

    We study the interior transmission eigenvalue problem for sign-definite multiplicative perturbations of the Laplacian in a bounded domain. We show that all but finitely many complex transmission eigenvalues are confined to a parabolic neighborhood of the positive real axis.

  2. A Novel Design of Circular Edge Bow-Tie Nano Antenna for Energy Harvesting

    NASA Astrophysics Data System (ADS)

    Haque, Ahasanul; Reza, Ahmed Wasif; Kumar, Narendra

    2015-11-01

    In this study, a novel nano antenna is designed in order to convert the high frequency solar energy, thermal energy or earth re-emitted sun's energy into electricity. The proposed antenna is gold printed on a SiO2 layer, designed as a circular edge bow-tie with a ground plane at the bottom of the substrate. The Lorentz-Drude model is used to analyze the behavior of gold at the infrared band of frequencies. The proposed antenna is designed by 3D-electromagnetic solver, and analyzed for optimization of metal thickness, gap size, and antenna's geometrical length. Simulations are conducted in order to investigate the behavior of the antenna illuminated by the circularly polarized plane wave. The numerical simulations are studied for improving the harvesting E-field of the antenna within 5 THz-40 THz frequency range. The proposed antenna offers multiple resonance frequency and better return loss within the frequency bands of 23.2 THz to 27 THz (bandwidth 3.8 THz) and 31 THz to 35.9 THz (bandwidth 4.9 THz). An output electric field of 0.656 V/µm is simulated at 25.3 THz. The best fitted gap size at the feed point is achieved as 50 nm with the substrate thickness of 1.2 µm.

  3. Performance degradation of grid-tied photovoltaic modules in a hot-dry climatic condition

    NASA Astrophysics Data System (ADS)

    Suleske, Adam; Singh, Jaspreet; Kuitche, Joseph; Tamizh-Mani, Govindasamy

    2011-09-01

    The crystalline silicon photovoltaic (PV) modules under open circuit conditions typically degrade at a rate of about 0.5% per year. However, it is suspected that the modules in an array level may degrade, depending on equipment/frame grounding and array grounding, at higher rates because of higher string voltage and increased module mismatch over the years of operation in the field. This paper compares and analyzes the degradation rates of grid-tied photovoltaic modules operating over 10-17 years in a desert climatic condition of Arizona. The nameplate open-circuit voltages of the arrays ranged between 400 and 450 V. Six different types/models of crystalline silicon modules with glass/glass and glass/polymer constructions were evaluated. About 1865 modules were inspected using an extended visual inspection checklist and infrared (IR) scanning. The visual inspection checklist included encapsulant discoloration, cell/interconnect cracks, delamination and corrosion. Based on the visual inspection and IR studies, a large fraction of these modules were identified as allegedly healthy and unhealthy modules and they were electrically isolated from the system for currentvoltage (I-V) measurements of individual modules. The annual degradation rate for each module type is determined based on the I-V measurements.

  4. Refinement of Strut-and-Tie Model for Reinforced Concrete Deep Beams

    PubMed Central

    Panjehpour, Mohammad; Chai, Hwa Kian; Voo, Yen Lei

    2015-01-01

    Deep beams are commonly used in tall buildings, offshore structures, and foundations. According to many codes and standards, strut-and-tie model (STM) is recommended as a rational approach for deep beam analyses. This research focuses on the STM recommended by ACI 318-11 and AASHTO LRFD and uses experimental results to modify the strut effectiveness factor in STM for reinforced concrete (RC) deep beams. This study aims to refine STM through the strut effectiveness factor and increase result accuracy. Six RC deep beams with different shear span to effective-depth ratios (a/d) of 0.75, 1.00, 1.25, 1.50, 1.75, and 2.00 were experimentally tested under a four-point bending set-up. The ultimate shear strength of deep beams obtained from non-linear finite element modeling and STM recommended by ACI 318-11 as well as AASHTO LRFD (2012) were compared with the experimental results. An empirical equation was proposed to modify the principal tensile strain value in the bottle-shaped strut of deep beams. The equation of the strut effectiveness factor from AASHTTO LRFD was then modified through the aforementioned empirical equation. An investigation on the failure mode and crack propagation in RC deep beams subjected to load was also conducted. PMID:26110268

  5. Physiology and Mechanism of Phototrophic Fe(II) Oxidation by Rhodopseudomonas palustris TIE-1

    NASA Astrophysics Data System (ADS)

    Jiao, Y.; Newman, D.

    2007-12-01

    Phototrophic Fe(II)-oxidizing bacteria use electrons from ferrous iron [Fe(II)] and energy from light to drive reductive CO2 fixation. This metabolism is thought to be ancient in origin, and plays an important role in environmental iron cycling. It has been implicated in the deposition of Banded Iron Formations, a class of ancient sedimentary iron deposits. Consistent with this hypothesis, we discovered that hydrogen gas, a thermodynamically favorable electron donor to Fe(II), in an Archean atmosphere would not have inhibited phototrophic Fe(II) oxidation. To understand this physiology and the connection to BIF formation at the molecular level, the mechanisms of phototrophic Fe(II) oxidation were examined in a model organism Rhodopseudomonas palustris TIE-1. Increased expression of a putative decaheme c-type cytochrome, encoded by pioA, was observed when cells were grown under Fe(II)-oxidizing conditions. Two genes located immediately downstream of pioA in the same operon, pioB and pioC, encode a putative outer membrane beta-barrel protein and a putative high potential iron-sulfur protein, respectively. Deletion studies demonstrated that all three genes are involved in phototrophic Fe(II) oxidation. This study provides our first insight into the molecular mechanisms of this metabolism, which will be further characterized by in vitro biochemical studies.

  6. Recent global-warming hiatus tied to equatorial Pacific surface cooling.

    PubMed

    Kosaka, Yu; Xie, Shang-Ping

    2013-09-19

    Despite the continued increase in atmospheric greenhouse gas concentrations, the annual-mean global temperature has not risen in the twenty-first century, challenging the prevailing view that anthropogenic forcing causes climate warming. Various mechanisms have been proposed for this hiatus in global warming, but their relative importance has not been quantified, hampering observational estimates of climate sensitivity. Here we show that accounting for recent cooling in the eastern equatorial Pacific reconciles climate simulations and observations. We present a novel method of uncovering mechanisms for global temperature change by prescribing, in addition to radiative forcing, the observed history of sea surface temperature over the central to eastern tropical Pacific in a climate model. Although the surface temperature prescription is limited to only 8.2% of the global surface, our model reproduces the annual-mean global temperature remarkably well with correlation coefficient r = 0.97 for 1970-2012 (which includes the current hiatus and a period of accelerated global warming). Moreover, our simulation captures major seasonal and regional characteristics of the hiatus, including the intensified Walker circulation, the winter cooling in northwestern North America and the prolonged drought in the southern USA. Our results show that the current hiatus is part of natural climate variability, tied specifically to a La-Niña-like decadal cooling. Although similar decadal hiatus events may occur in the future, the multi-decadal warming trend is very likely to continue with greenhouse gas increase. PMID:23995690

  7. Tie-In Orbits for the Focal Plane Stability Test - Part 2

    NASA Astrophysics Data System (ADS)

    Abramowicz-Reed, Linda

    1991-07-01

    This proposal is part of the TTSC request entitled, "Distortion Calibration in FGS 1 and FGS 2, FGS-to-FGS Alignment Calibration". This portion is listed separately due to the time critical nature of one of the orbits. OFAD in FGS 3 which will be performed in December 1992 together with the Mini OFAD's in FGS's 1 and 2 which will be performed in January 1993 will provide a new set of FGS calibration parameters. One of the objectives of the STScI Focal Plane Stability test is to monitor changes to these parameters by repeatedly observing targets in the cluster M35. Since the cluster is near the ecliptic, only two vehicle orientations are needed, the "fall" and the "spring" pointings (see attached pickles plots). Since the Mini OFAD targets are not necessarily the same targets used in the Focal Plane Stability Test, tie in orbits using the Focal Plane Stability targets are needed shortly before and after the Mini OFAD activities. In addition, the Focal Plane Stability Test may not be

  8. Impact of Magnetic Draping, Convection, and Field Line Tying on Magnetopause Reconnection Under Northward IMF

    NASA Technical Reports Server (NTRS)

    Wendel, Deirdre E.; Reiff, Patricia H.; Goldstein, Melvyn L.

    2010-01-01

    We simulate a northward IMF cusp reconnection event at the magnetopause using the OpenGGCM resistive MHD code. The ACE input data, solar wind parameters, and dipole tilt belong to a 2002 reconnection event observed by IMAGE and Cluster. Based on a fully three-dimensional skeleton separators, nulls, and parallel electric fields, we show magnetic draping, convection, ionospheric field line tying play a role in producing a series of locally reconnecting nulls with flux ropes. The flux ropes in the cusp along the global separator line of symmetry. In 2D projection, the flux ropes the appearance of a tearing mode with a series of 'x's' and 'o's' but bearing a kind of 'guide field' that exists only within the magnetopause. The reconnecting field lines in the string of ropes involve IMF and both open and closed Earth magnetic field lines. The observed magnetic geometry reproduces the findings of a superposed epoch impact parameter study derived from the Cluster magnetometer data for the same event. The observed geometry has repercussions for spacecraft observations of cusp reconnection and for the imposed boundary conditions reconnection simulations.

  9. Lipid remodeling in Rhodopseudomonas palustris TIE-1 upon loss of hopanoids and hopanoid methylation.

    PubMed

    Neubauer, C; Dalleska, N F; Cowley, E S; Shikuma, N J; Wu, C-H; Sessions, A L; Newman, D K

    2015-09-01

    The sedimentary record of molecular fossils (biomarkers) can potentially provide important insights into the composition of ancient organisms; however, it only captures a small portion of their original lipid content. To interpret what remains, it is important to consider the potential for functional overlap between different lipids in living cells, and how the presence of one type might impact the abundance of another. Hopanoids are a diverse class of steroid analogs made by bacteria and found in soils, sediments, and sedimentary rocks. Here, we examine the trade-off between hopanoid production and that of other membrane lipids. We compare lipidomes of the metabolically versatile ?-proteobacterium Rhodopseudomonas palustris TIE-1 and two hopanoid mutants, detecting native hopanoids simultaneously with other types of polar lipids by electrospray ionization mass spectrometry. In all strains, the phospholipids contain high levels of unsaturated fatty acids (often >80%). The degree to which unsaturated fatty acids are modified to cyclopropyl fatty acids varies by phospholipid class. Deletion of the capacity for hopanoid production is accompanied by substantive changes to the lipidome, including a several-fold rise of cardiolipins. Deletion of the ability to make methylated hopanoids has a more subtle effect; however, under photoautotrophic growth conditions, tetrahymanols are upregulated twofold. Together, these results illustrate that the 'lipid fingerprint' produced by a micro-organism can vary depending on the growth condition or loss of single genes, reminding us that the absence of a biomarker does not necessarily imply the absence of a particular source organism. PMID:25923996

  10. Hot Carrier Reliability Study in Body-Tied Fin-Type Field Effect Transistors

    NASA Astrophysics Data System (ADS)

    Han, Jin?Woo; Lee, Choong?Ho; Park, Donggun; Choi, Yang?Kyu

    2006-04-01

    Hot-carrier effects in body-tied fin-type field effect transistors (FinFETs) are investigated. As the gate bias increases, coupling effects of two gates facing each other suppress the lateral channel electric field more effectively at double gate metal oxide FETs (MOSFETs) than at single gate MOSFETs. In double gate FinFETs, this effect is even further enhanced when the fin width is narrowed. The substrate current produced by an impact ionization process becomes large as fin width increases. In the generalized substrate current model, the maximum substrate current bias condition is approximately VG/VD˜ 0.5. However, in the double-gate FinFETs, it was (VG-VT)/VD˜ 0.3. There are two competing stress conditions: the maximum substrate current condition, and the maximum gate current condition. Device degradation is compared for various fin widths after both type of stress. It was found that the maximum substrate current stress condition degraded the device more significantly. The narrow fin is more immune to both stress biases than the wide fin. Thus, the narrow fin is appropriate for further device scaling and reliability. The supply voltage which corresponds to a 10-years lifetime was 1.31 V for the worst hot-carrier stress case.

  11. Experiment on the stability of zero net current, line tied screw pinch

    NASA Astrophysics Data System (ADS)

    Stambler, Sam; Bergerson, W.; Fiksel, G.; Forest, C. B.; Grierson, B.; Hannum, D.; Hegna, C.; Kendrick, R.; Oliva, S.; Sarff, J.

    2004-11-01

    Coronal loops emerging from the solar surface without current are expected to be twisted by convective motion of the footpoints. The resulting equilibrium has zero net current, with current of one sign in the center of the loop and of the opposite sign in the periphery of the loop [Lionello 98]. While the stability of line tied pinch plasmas with net current have been studied, both experimentally and theoretically, relatively little has been done to study the zero net current case. This geometry is investigated in a 1 m long plasma column produced by an array of plasma guns in the Rotating Wall Machine. For this experiment a circle of six cathode guns inject current from one end, while a seventh gun injects current of the opposite sign from the opposite end in the center of the plasma column, forming a coaxial current distribution with no net current. MHD stability is monitored by a two dimensional array of flux loops, mounted outside the first wall. Internal magnetic probes are used to measure the axial, poloidal and radial fields for the study of the internal kink structure.

  12. A New Approach to Design of an optimized Grid Tied Smart Solar Photovoltaic (PV) System

    NASA Astrophysics Data System (ADS)

    Farhad, M. Mehedi; Ali, M. Mohammad; Iqbal, M. Asif; Islam, N. Nahar; Ashraf, N.

    2012-11-01

    Energy is the key element for the economical development of a country. With the increasing concern about the global demand for Renewable Energy (RE) energy, it is very much important to reduce the cost of the whole solar photovoltaic (PV) system. Still now most of the solar photovoltaic (PV) system is highly expensive. In this paper we have shown that grid tied solar system can be developed by omitting the energy storage device like large capacity battery bank. It will not only reduce the internallosses for charging and discharging of battery bank but also at the same time a large amount of cost of the battery will be reduced. So, the system maintenance cost will be reduced also. We have proposed a new approach to design a photovoltaic (PV) solar power system which can be operated by feeding the solar power to the national grid along with the residential load. Again if there is an extra power demand for residential load along with the solar power then this system can also provide an opportunity to consume the power from the national grid. The total system is controlled with the help of some the sensors and a microcontroller. As a whole a significant reduction in the system costs and efficient system performance can be realized.

  13. From Dyadic Ties to Information Infrastructures: Care-Coordination between Patients, Providers, Students and Researchers

    PubMed Central

    Purkayastha, S.; Biswas, R.; Jai Ganesh, A.U.; Otero, P.

    2015-01-01

    Summary Objective To share how an effectual merging of local and online networks in low resource regions can supplement and strengthen the local practice of patient centered care through the use of an online digital infrastructure powered by all stakeholders in healthcare. User Driven Health Care offers the dynamic integration of patient values and evidence based solutions for improved medical communication in medical care. Introduction This paper conceptualizes patient care-coordination through the lens of engaged stakeholders using digital infrastructures tools to integrate information technology. We distinguish this lens from the prevalent conceptualization of dyadic ties between clinician-patient, patient-nurse, clinician-nurse, and offer the holistic integration of all stakeholder inputs, in the clinic and augmented by online communication in a multi-national setting. Methods We analyze an instance of the user-driven health care (UDHC), a network of providers, patients, students and researchers working together to help manage patient care. The network currently focuses on patients from LMICs, but the provider network is global in reach. We describe UDHC and its opportunities and challenges in care-coordination to reduce costs, bring equity, and improve care quality and share evidence. Conclusion UDHC has resulted in coordinated global based local care, affecting multiple facets of medical practice. Shared information resources between providers with disparate knowledge, results in better understanding by patients, unique and challenging cases for students, innovative community based research and discovery learning for all. PMID:26123908

  14. TIE of a PAH-contaminated sediment using reproductive responses and EROD induction in rainbow trout

    SciTech Connect

    Brumley, C.M.; Kraak, G. van der; Munkittrick, K.R.

    1995-12-31

    PAH-contaminated sediments have been shown to cause a range of effects in fish. However, identifying the effective compounds can be time consuming and expensive. A toxicity identification evaluation (TIE) involves the analysis of mixtures by initially separating the mixture into toxic and non-toxic constituents. In this study, sediment was collected from Hamilton Harbor, Lake Ontario, and either extracted wet using methanol (MeOH) and dichloromethane (DCM), or freeze-dried and soxhlet extracted with MeOH and DCM. DCM extracts were solvent exchanged with dimethylsulfoxide (DMSO). Juvenile rainbow trout (Oncorhynchus mykiss) were exposed through the water to wet, freeze-dried, or extracted sediment, or to the MeOH or DMSO extracts for 4 days. Fish were analyzed for hepatic EROD activity, and plasma DMSO extracts, but was unaffected in fish exposed to extracted sediment. Estradiol levels were increased in fish exposed to the wet sediment, but not in fish exposed to the freeze-dried or extracted sediment, nor either of the solvent extracts. The response of testosterone to wet, freeze-dried and extracted sediment was inconsistent. Results indicate that both of the extraction methods efficiently removed from the sediment the compounds responsible for the effects on EROD activity and estradiol levels. However, neither method retained in the solvent extracts the compounds causing the increases in estradiol levels. Work continues to refine the freeze-drying and extraction methods; extracts will then be further fractionated using HPLC to identify the compounds of concern.

  15. A numerical simulation of magnetic reconnection and radiative cooling in line-tied current sheets

    NASA Technical Reports Server (NTRS)

    Forbes, T. G.; Malherbe, J. M.

    1991-01-01

    Radiative MHD equations are used for an optically thin plasma to carry out a numerical experiment related to the formation of 'postflare' loops. The numerical experiment starts with a current sheet that is in mechanical and thermal equilibrium but is unstable to both tearing-mode and thermal-condensation instabilities. The current sheet is line-tied at one end to a photospheric-like boundary and evolves asymmetrically. The effects of thermal conduction, resistivity variation, and gravity are ignored. In general, reconnection in the nonlinear stage of the tearing-mode instability can strongly affect the onset of condensations unless the radiative-cooling time scale is much smaller than the tearing-mode time scale. When the ambient plasma is less than 0.2, the reconnection enters a regime where the outflow from the reconnection region is supermagnetosonic with respect to the fast-mode wave speed. In the supermagnetosonic regime the most rapidly condensing regions occur downstream of a fast-mode shock that forms where the outflow impinges on closed loops attached to the photospheric-like boundary. A similar shock-induced condensation might occur during the formation of 'postflare' loops.

  16. High strength-of-ties and low mobility enable the evolution of third-party punishment.

    PubMed

    Roos, Patrick; Gelfand, Michele; Nau, Dana; Carr, Ryan

    2014-02-01

    As punishment can be essential to cooperation and norm maintenance but costly to the punisher, many evolutionary game-theoretic studies have explored how direct punishment can evolve in populations. Compared to direct punishment, in which an agent acts to punish another for an interaction in which both parties were involved, the evolution of third-party punishment (3PP) is even more puzzling, because the punishing agent itself was not involved in the original interaction. Despite significant empirical studies of 3PP, little is known about the conditions under which it can evolve. We find that punishment reputation is not, by itself, sufficient for the evolution of 3PP. Drawing on research streams in sociology and psychology, we implement a structured population model and show that high strength-of-ties and low mobility are critical for the evolution of responsible 3PP. Only in such settings of high social-structural constraint are punishers able to induce self-interested agents toward cooperation, making responsible 3PP ultimately beneficial to individuals as well as the collective. Our results illuminate the conditions under which 3PP is evolutionarily adaptive in populations. Responsible 3PP can evolve and induce cooperation in cases where other mechanisms alone fail to do so. PMID:24335985

  17. Plasma vascular endothelial growth factor, angiopoietin-2, and soluble angiopoietin receptor tie-2 in diabetic retinopathy: effects of laser photocoagulation and angiotensin receptor blockade

    PubMed Central

    Lip, P L; Chatterjee, S; Caine, G J; Hope-Ross, M; Gibson, J; Blann, A D; Lip, G Y H

    2004-01-01

    Background: Proliferative diabetic retinopathy (PDR) may be a response to abnormal angiogenic growth factors such as vascular endothelial growth factor (VEGF), angiopoietin-2 (Ang-2), and the soluble angiopoietin receptor tie-2. The authors hypothesised the following: (a) there are differences in plasma levels of these growth factors in different grades of diabetic retinopathy; and (b) that the effects of intervention with panretinal laser photocoagulation (PRP) for PDR, and angiotensin receptor blockade (using eprosartan) for patients with other grades of diabetic retinopathy will be to reduce levels of the growth factors. Methods: Cross sectional and interventional study (using PRP and eprosartan) in diabetic patients. VEGF, Ang-2, and tie-2 were measured by ELISA. Results: VEGF (p<0.001) and Ang-2 levels (p<0.001) were significantly higher in 93 diabetic patients compared to 20 healthy controls, with the highest levels in grade 2 and grade 3 diabetic retinopathy (p<0.05). Tie-2 was lower in diabetics compared to controls (p?=?0.008), with no significant differences between the diabetic subgroups. Overall, VEGF significantly correlated with Ang-2 (p<0.001) and tie-2 (p?=?0.004) but the correlation between Ang-2 and tie-2 levels was not significant (p?=?0.065). Among diabetic patients only, VEGF levels were significantly correlated with Ang-2 (p<0.001) and tie-2 (p<0.001); the correlation between Ang-2 and tie-2 levels was also significant (p<0.001). There were no statistically significant effects of laser photocoagulation on plasma VEGF, Ang-2, and tie-2 in the 19 patients with PDR, or any effects of eprosartan in the 28 patients with non-proliferative diabetic retinopathy. Conclusion: Increased plasma levels of VEGF and Ang-2, as well as lower soluble tie-2, were found in diabetic patients. The highest VEGF and Ang-2 levels were seen among patients with pre-proliferative and proliferative retinopathy, but there was no relation of tie-2 to the severity of retinopathy. As the majority of previous research into Ang-2 and tie-2 has been in relation to angiogenesis and malignancy, the present study would suggest that Ang-2 and tie-2 may be used as potential indices of angiogenesis in diabetes mellitus (in addition to VEGF) and may help elucidate the role of the angiopoietin/tie-2 system in this condition. PMID:15548809

  18. Automatic transmission for motor vehicles

    SciTech Connect

    Miura, M.; Sakakibara, S.

    1989-06-27

    An automatic transmission for a motor vehicle is described, comprising: a transmission housing; a hydraulic torque converter having rotational axes, an input shaft, an output shaft and a direct coupling clutch for directly coupling the input shaft to the output shaft; an auxiliary transmission mechanism provided coaxially with the hydraulic torque converter and having an input shaft, an output shaft with an input end and an output end and an overdrive mechanism of planetary gear type having a reduction ratio smaller than 1, the input shaft and the output shaft of the auxiliary transmission being located close to and on the side of the hydraulic torque converter with respect to the auxiliary transmission, respectively, and being coupled with a planetary gear carrier and a ring gear of the overdrive mechanism, respectively, a one-way clutch being provided between the planetary gear carrier and a sun gear of the overdrive mechanism, a clutch being provided between the planetary gear carrier and a position radially and outwardly of the one-way clutch for engaging the disengaging the planetary carrier and the sun gear, a brake being provided between the transmission housing and the sun gear and positioned radially and outwardly of the clutch for controlling engagement of the sun gear with a stationary portion of the transmission housing, and the output end of the output shaft being disposed between the auxiliary transmission mechanism and the hydraulic torque converter.

  19. A Quantitative Transmission Line Experiment

    ERIC Educational Resources Information Center

    Johnston, D. C.; Silbernagel, B. G.

    1969-01-01

    Describes modifications of a commercially available strip-type transmission line, which makes possible reproducible measurements of standing waves on the line. Experimental data yield values for the characteristic impedance, phase velocity and line wavelength of radiation in the transmission line, and the dielectric constant of material in the…

  20. Transmission Line Circuit Alexander Glasser

    E-print Network

    Anlage, Steven

    Chaos in a Transmission Line Circuit Alexander Glasser Marshal Miller With... Prof. Edward Ott Prof times become shorter, circuit connections behave more and more like transmission lines. Theoretical in a computer chip #12;Picture of Circuit g Rg Vref Vinc nonlinear capacitor resistor Diode Vg(t) Model + V

  1. Amphibian ranavirus transmission and persistence

    E-print Network

    Gray, Matthew

    undergoing die-offs to kiddie pools with wood frog tadpoles Routes of transmission: via water #12;Are. 2011 " RUK Cunningham et al. 2007 " LMBV Grant et al. 2003 " Small particles (filtered water) and chunky bits (filtrate) are both very infectious (Brunner et al. 2007) Routes of transmission: via water

  2. HVDC power transmission technology assessment

    SciTech Connect

    Hauth, R.L.; Tatro, P.J.; Railing, B.D.; Johnson, B.K.; Stewart, J.R.; Fink, J.L.

    1997-04-01

    The purpose of this study was to develop an assessment of the national utility system`s needs for electric transmission during the period 1995-2020 that could be met by future reduced-cost HVDC systems. The assessment was to include an economic evaluation of HVDC as a means for meeting those needs as well as a comparison with competing technologies such as ac transmission with and without Flexible AC Transmission System (FACTS) controllers. The role of force commutated dc converters was to be assumed where appropriate. The assessment begins by identifying the general needs for transmission in the U.S. in the context of a future deregulated power industry. The possible roles for direct current transmission are then postulated in terms of representative scenarios. A few of the scenarios are illustrated with the help of actual U.S. system examples. non-traditional applications as well as traditional applications such as long lines and asynchronous interconnections are discussed. The classical ``break-even distance`` concept for comparing HVDC and ac lines is used to assess the selected scenarios. The impact of reduced-cost converters is reflected in terms of the break-even distance. This report presents a comprehensive review of the functional benefits of HVDC transmission and updated cost data for both ac and dc system components. It also provides some provocative thoughts on how direct current transmission might be applied to better utilize and expand our nation`s increasingly stressed transmission assets.

  3. Identification and Preliminary SAR Analysis of Novel Type-I Inhibitors of TIE-2 via Structure-Based Virtual Screening and Biological Evaluation in in vitro Models.

    PubMed

    Pan, Peichen; Tian, Sheng; Sun, Huiyong; Kong, Xiaotian; Zhou, Wenfang; Li, Dan; Li, Youyong; Hou, Tingjun

    2015-12-28

    Angiopoietin (ANG) ligands and their downstream TIE receptors have been validated as the second vascular signaling system involving vessel remodeling and maturation. Among them, the ANG/TIE-2 signaling pathway is involved in numerous life-threatening diseases and has become an attractive potential therapeutic target. Several large-molecule inhibitors targeting the ANG/TIE-2 axis have recently entered clinical phase for the therapy of various solid tumors, but selective small-molecule inhibitors of TIE-2 are still quite limited. In the present work, structure-based virtual screening was performed to search for type-I inhibitors of TIE-2. Of the only 41 compounds selected by our strategy, 8 molecules with the concentration of 25 ?g/mL exhibit over 50% inhibitory rate against TIE-2 in in vitro enzymatic activity assay, and the IC50 values of 2 hits are lower than 1 ?M. Further optimization and SAR analysis based on compound TP-S1-30 and 31 were carried out by using substructure searching strategy, leading to the discovery of several sub-100 nM inhibitors. Among them, the most potent compound, TP-S1-68, showed an inhibitory IC50 of 0.149 ?M. These novel inhibitors of TIE-2 discovered in this study and the analogs of the active core scaffolds can serve as the starting points for further drug development. PMID:26618892

  4. Regional Transmission Projects: Finding Solutions

    SciTech Connect

    The Keystone Center

    2005-06-15

    The Keystone Center convened and facilitated a year-long Dialogue on "Regional Transmission Projects: Finding Solutions" to develop recommendations that will help address the difficult and contentious issues related to expansions of regional electric transmission systems that are needed for reliable and economic transmission of power within and across regions. This effort brought together a cross-section of affected stakeholders and thought leaders to address the problem with the collective wisdom of their experience and interests. Transmission owners sat at the table with consumer advocates and environmental organizations. Representatives from regional transmission organizations exchanged ideas with state and federal regulators. Generation developers explored common interests with public power suppliers. Together, the Dialogue participants developed consensus solutions about how to begin unraveling some of the more intractable issues surrounding identification of need, allocation of costs, and reaching consensus on siting issues that can frustrate the development of regional transmission infrastructure. The recommendations fall into three broad categories: 1. Recommendations on appropriate institutional arrangements and processes for achieving regional consensus on the need for new or expanded transmission infrastructure 2. Recommendations on the process for siting of transmission lines 3. Recommendations on the tools needed to support regional planning, cost allocation, and siting efforts. List of Dialogue participants: List of Dialogue Participants: American Electric Power American Transmission Company American Wind Energy Association California ISO Calpine Corporation Cinergy Edison Electric Institute Environmental Defense Federal Energy Regulatory Commission Great River Energy International Transmission Company ISO-New England Iowa Public Utility Board Kanner & Associates Midwest ISO National Association of Regulatory Utility Commissioners National Association of State Utility Consumer Advocates National Grid Northeast Utilities PA Office of Consumer Advocates Pacific Gas & Electric Corporation Pennsylvania Public Utility Commission PJM Interconnection The Electricity Consumers Resource Council U.S. Department of Energy US Department of the Interior Van Ness Feldman Western Interstate Energy Board Wind on the Wires Wisconsin Public Service Commission Xcel Energy

  5. Automatic transmission system

    SciTech Connect

    Ha, J.S.

    1989-04-25

    An automatic transmission system is described for use in vehicles, which comprises: a clutch wheel containing a plurality of concentric rings of decreasing diameter, the clutch wheel being attached to an engine of the vehicle; a plurality of clutch gears corresponding in size to the concentric rings, the clutch gears being adapted to selectively and frictionally engage with the concentric rings of the clutch wheel; an accelerator pedal and a gear selector, the accelerator pedals being connected to one end of a substantially U-shaped frame member, the other end of the substantially U-shaped frame member selectively engaging with one end of one of wires received in a pair of apertures of the gear selector; a plurality of drive gear controllers and a reverse gear controller; means operatively connected with the gear selector and the plurality of drive gear controllers and reverse gear controller for selectively engaging one of the drive and reverse gear controllers depending upon the position of the gear selector; and means for individually connecting the drive and reverse gear controllers with the corresponding clutch gears whereby upon the selection of the gear selector, friction engagement is achieved between the clutch gear and the clutch wheels for rotating the wheel in the forward or reverse direction.

  6. Countershaft automatic transmission

    SciTech Connect

    Pierce, S.L.

    1987-09-15

    This patent describes a multiple speed ratio transmission for use in delivering torque from an engine comprising: an output shaft; an input pinion continuously driven by the engine; first clutch means for selectively connecting the engine to the output shaft; a countershaft mounted for rotation parallel to the output shaft; gearing defining multiple pairs of meshing gears and pinions including a first group of such pairs having the gears rotatably mounted on the output shaft and the pinions formed integrally with a gear wheel. The pinions are rotatably mounted on the countershaft and driven from the input pinion. The gearing further includes a second gear-pinion pair having the gear of the second gear-pinion pair rotatably mounted on the output shaft and the pinion of the second gear-pinion pair non-rotatably connected to the countershaft; second clutch means for selectively driveably connecting the input pinion to the countershaft; first coupler means for selectively driveably connecting the gear of a gear-pinion pair of the first group to the output shaft; and second coupler means for selectively driveably connecting the gear of the second gear-pinion pair to the output shaft.

  7. EC Transmission Line Materials

    SciTech Connect

    Bigelow, Tim S

    2012-05-01

    The purpose of this document is to identify materials acceptable for use in the US ITER Project Office (USIPO)-supplied components for the ITER Electron cyclotron Heating and Current Drive (ECH&CD) transmission lines (TL), PBS-52. The source of material property information for design analysis shall be either the applicable structural code or the ITER Material Properties Handbook. In the case of conflict, the ITER Material Properties Handbook shall take precedence. Materials selection, and use, shall follow the guidelines established in the Materials Assessment Report (MAR). Materials exposed to vacuum shall conform to the ITER Vacuum Handbook. [Ref. 2] Commercial materials shall conform to the applicable standard (e.g., ASTM, JIS, DIN) for the definition of their grade, physical, chemical and electrical properties and related testing. All materials for which a suitable certification from the supplier is not available shall be tested to determine the relevant properties, as part of the procurement. A complete traceability of all the materials including welding materials shall be provided. Halogenated materials (example: insulating materials) shall be forbidden in areas served by the detritiation systems. Exceptions must be approved by the Tritium System and Safety Section Responsible Officers.

  8. Transmissive Microshutter Arrays

    NASA Astrophysics Data System (ADS)

    Kutyrev, A. S.; Moseley, H. S.; Fettig, R. K.; Kuhn, J. L.; Woodgate, B. E.; Kimble, R. A.; Orloff, J. H.

    1999-12-01

    We report further progress on the development of a two-dimensional array of microshutters, which can be used as a high efficiency, high contrast field selection device for a multi-object spectrometer for the Next Generation Space Telescope (NGST). The device is a close packed array of shutters, with a typical size of 100 microns square and an area filling factor of up to 80%. Each shutter, made of single crystal silicon or silicon nitride with an appropriate optical coating, pivots on a torsion flexure along one edge. Each of the shutters is individually selectable. Although these devices can be used as reflection devices, their primary mode of operation is in transmission, which provides the minimum possible level of scattered light. An original double-shutter mechanism is employed for actuation. Small shutter arrays have been built using a Focus Ion Beam milling machine is a 3 x 3 double shutter actuation with a micro-manipulator under electron microscope observation has been demonstrated. An important aspect of this study has been to demonstrate the reliability of the structures over its expected lifetime. We analyzed stiffness, strength and fatigue issues of two good candidate materials, single crystal silicon and silicon nitride. Both appear to be suitable from the mechanical point of view. This project is supported by NASA grants.

  9. Electronically controlled automatic transmission

    SciTech Connect

    Ohkubo, M.; Shiba, H.; Nakamura, K.

    1989-03-28

    This patent describes an electronically controlled automatic transmission having a manual valve working in connection with a manual shift lever, shift valves operated by solenoid valves which are driven by an electronic control circuit previously memorizing shift patterns, and a hydraulic circuit controlled by these manual valve and shift valves for driving brakes and a clutch in order to change speed. Shift patterns of 2-range and L-range, in addition to a shift pattern of D-range, are memorized previously in the electronic control circuit, an operation switch is provided which changes the shift pattern of the electronic control circuit to any shift pattern among those of D-range, 2-range and L-range at time of the manual shift lever being in a D-range position, a releasable lock mechanism is provided which prevents the manual shift lever from entering 2-range and L-range positions, and the hydraulic circuit is set to a third speed mode when the manual shift lever is in the D-range position. The circuit is set to a second speed mode when it is in the 2-range position, and the circuit is set to a first speed mode when it is in the L-range position, respectively, in case where the shift valves are not working.

  10. Influence of Line-Tied Boundary Conditions on the Development of Magnetic Reconnection in Force-Free Current Layers

    NASA Astrophysics Data System (ADS)

    Akcay, Cihan; Daughton, William; Stanier, Adam; Lukin, Vyacheslav

    2014-10-01

    The evolution of plasmas in magnetically dominated low- ? regimes often leads to the formation of nearly force-free current sheets where magnetic reconnection may be triggered by the tearing instability. In this study, we examine the influence of line-tied boundary conditions on the onset and development of three-dimensional magnetic reconnection in kinetic-scale force-free layers. To better understand the physics, we perform cross-comparisons between fully kinetic VPIC simulations and two-fluid HiFi simulations. We focus on a range of guide fields Bg = (1 - 10) B0 relevant to both space and laboratory plasmas, and compare the evolution between systems with line-tied and periodic boundary conditions.

  11. Morphologies of emulsions of conjugate phase pairs of amphiphile/oil/water {open_quotes}microemulsion{close_quotes} tie triangles

    SciTech Connect

    Smith, D.H.; Nwosu, S.N.; Johnson, G.K.

    1992-04-01

    Electrical conductivity measurements were made on emulsions formed, respectively, from the conjugate top-middle, top-bottom, and middle-bottom phase pairs that define the three sides of various nonionic amphiphile/oil/water {open_quotes}microemulsion{close_quotes} tie triangles. Effective-medium conductivity models and observations of creaming behavior were used to substantiate assignments of steady-state emulsion morphologies. The phase volume fractions at which morphology changes occurred were measured for both directions along each tie line, and the hysteresis was obtained as the difference between the volume fractions for the two directions. The results support the dispersion morphology diagram previously postulated, including the formation of mixtures of emulsions whose morphologies are the inverse of each other. 31 refs., 8 figs., 3 tabs.

  12. Pattern Switchable Antenna System Using Inkjet-Printed Directional Bow-Tie for Bi-Direction Sensing Applications.

    PubMed

    Eom, Seung-Hyun; Seo, Yunsik; Lim, Sungjoon

    2015-01-01

    In this paper, we propose a paper-based pattern switchable antenna system using inkjet-printing technology for bi-direction sensor applications. The proposed antenna system is composed of two directional bow-tie antennas and a switching network. The switching network consists of a single-pole-double-throw (SPDT) switch and a balun element. A double-sided parallel-strip line (DSPSL) is employed to convert the unbalanced microstrip mode to the balanced strip mode. Two directional bow-tie antennas have different radiation patterns because of the different orientation of the reflectors and antennas. It is demonstrated from electromagnetic (EM) simulation and measurement that the radiation patterns of the proposed antenna are successfully switched by the SPDT switch. PMID:26690443

  13. Long lifetime current driven rotating kink modes in a non line-tied plasma column with a free end

    NASA Astrophysics Data System (ADS)

    Furno, I.; Intrator, T. P.; Ryutov, D. D.; Abbate, S.; Madziwa-Nussinov, T.; Light, A.; Dorf, L.; Lapenta, G.

    2006-10-01

    We show the first experimental evidence [1] for a magnetohydrodynamic kink instability in a current rope with one end that is free to move. This free end is insulated by sheath resistivity, which breaks MHD, and is thus not line tied to the axial boundary. We find instability threshold well below the classical Kruskal-Shafranov threshold. The presence of an axial flow gives rise to a doppler shifted frequency and rotation of the kink where the eigenfunction is axially pushed in the flow direction. This oscillating and rotating state persists indefinitely without disruptions for a long lifetime. Striking agreement with a theoretical analysis is demonstrated. [1] I. Furno, T. P. Intrator, D.D. Ryutov et al. ``Current-Driven Rotating-Kink Mode in a Plasma Column with a Non-Line-Tied Free End.'' Physical Review Letters, 97: 015002 (2006).

  14. Inner Workings of Gene Tied to Breast Ovarian Cancer Revealed -Print -MSN Health & Fitness http://health.msn.com/print.aspx?cp-documentid=100262630&page=0[8/24/2010 3:20:16 PM

    E-print Network

    Kowalczykowski, Stephen C.

    Inner Workings of Gene Tied to Breast Ovarian Cancer Revealed - Print - MSN Health & Fitness http://health.msn.com/print.aspx?cp-documentid=100262630&page=0[8/24/2010 3:20:16 PM] Inner Workings of Gene Tied to Breast, Ovarian Cancer Revealed In 3 of Gene Tied to Breast Ovarian Cancer Revealed - Print - MSN Health & Fitness http

  15. Formation and maintenance of single-thread tie channels entering floodplain lakes: Observations from three diverse river systems

    NASA Astrophysics Data System (ADS)

    Rowland, J. C.; Dietrich, W. E.; Day, G.; Parker, G.

    2009-06-01

    Tie channels connect rivers to floodplain lakes on many lowland rivers and thereby play a central role in floodplain sedimentology and ecology; yet they are generally unrecognized and little studied. Here we report the results of field studies focused on tie channel origin and morphodynamics in the following three contrasting systems: the Middle Fly River (Papua New Guinea), the Lower Mississippi River, and Birch Creek in Alaska. Across these river systems, tie channels vary by an order of magnitude in size but exhibit the same characteristic morphology and appear to develop and evolve by a similar set of processes. In all three systems, the channels are characterized by a narrow, leveed, single-thread morphology with maximum width approximately one tenth the width of the mainstem river. The channels typically have a V-shaped cross section, unlike most fluvial channels. These channels develop as lakes become isolated from the river by sedimentation. Narrowing of the connection between river and lake causes a sediment-laden jet to develop. Levees develop along the margins of the jet leading to channel emergence and eventual levee aggradation to the height of the mainstem levees. Bidirectional flow in these channels is common. Outflows from the lake scour sediment and prevent channel blockage. We propose that channel geometry and size are then controlled by a dynamic balance between channel narrowing by suspended sediment deposition and incision and widening by mass failure of banks during outflows. Tie channels are laterally stable and may convey flow for hundreds to a few thousand of years.

  16. MALARIA I N NIGERIA: CDNSTRAINED CaYTINUXIS-TIE MARKDV MmLS A3R DISCRETE-TIME

    E-print Network

    Cohen, Joel E.

    MALARIA I N NIGERIA: CDNSTRAINED CaYTINUXIS-TIE MARKDV MmLS A3R DISCRETE-TIME ~ I T U D I N of the endemicity of malaria will be essential i n a population which is t o receive an acceptable malaria vaccine another." V. Nabokov (1972, p. 8) Abstract A research project on malaria i n the Garki d i s t r i c

  17. Determination of the local tie vector between the VLBI and GNSS reference points at Onsala using GPS measurements

    NASA Astrophysics Data System (ADS)

    Ning, T.; Haas, R.; Elgered, G.

    2015-07-01

    Two gimbal-mounted GNSS antennas were installed on each side of the radome-enclosed 20 m VLBI radio telescope at the Onsala Space Observatory. GPS data with a 1 Hz sampling rate were recorded for five semi-kinematic and four kinematic observing campaigns. These GPS data were analysed together with data from the IGS station ONSA with an in-house Matlab-based GPS software package, using the double-difference analysis strategy. The coordinates of the GNSS antennas on the telescope were estimated for different observation angles of the telescope, at specific epochs, and used to calculate the geodetic reference point of the telescope. The local tie vector between the VLBI and the ONSA GNSS reference points in a geocentric reference frame was hence obtained. The two different types of observing campaigns gave consistent results of the estimated local tie vector and the axis offset of the telescope. The estimated local tie vector obtained from all nine campaigns gave standard deviations of 1.5, 1.0, and 2.9 mm for the geocentric X, Y, and Z components, respectively. The result of the estimated axis offset of the VLBI telescope shows a difference of 0.3 mm, with a standard deviation of 1.9 mm, with respect to a reference value obtained by two local surveys carried out in 2002 and 2008. Our results show that the presented method can be used as a complement to the more accurate but more labour intensive classical geodetic surveys to continuously monitor the local tie at co-location stations with an accuracy of a few millimetres.

  18. The synthetic Tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis

    PubMed Central

    2011-01-01

    Introduction Angiopoietin-1 (Angpt1), the natural agonist ligand for the endothelial Tie2 receptor, is a non-redundant endothelial survival and vascular stabilization factor that reduces endothelial permeability and inhibits leukocyte-endothelium interactions. Here we evaluate the efficacy of a novel polyethylene glycol (PEG)-clustered Tie2 agonist peptide, vasculotide (VT), to protect against vascular leakage and mortality in a murine model of polymicrobial abdominal sepsis. Methods Polymicrobial abdominal sepsis in C57BL6 mice was induced by cecal-ligation-and-puncture (CLP). Mice were treated with different dosages of VT or equal volume of phosphate-buffered saline (PBS). Sham-operated animals served as time-matched controls. Results Systemic administration of VT induced long-lasting Tie2 activation in vivo. VT protected against sepsis-induced endothelial barrier dysfunction, as evidenced by attenuation of vascular leakage and leukocyte transmigration into the peritoneal cavity. Histological analysis revealed that VT treatment ameliorated leukocyte infiltration in kidneys of septic mice, probably due to reduced endothelial adhesion molecule expression. VT-driven effects were associated with significantly improved organ function and reduced circulating cytokine levels. The endothelial-specific action of VT was supported by additional in vitro studies showing no effect of VT on either cytokine release from isolated peritoneal macrophages, or migratory capacity of isolated neutrophils. Finally, administration of VT pre-CLP (hazard ratio 0.39 [95% confidence interval 0.19-0.81] P < 0.001) and post-CLP reduced mortality in septic mice (HR 0.22 [95% CI 0.06-0.83] P < 0.05). Conclusions We provide proof of principle in support of the efficacious use of PEGylated VT, a drug-like Tie2 receptor agonist, to counteract microvascular endothelial barrier dysfunction and reduce mortality in a clinically relevant murine sepsis model. Further studies are needed to pave the road for clinical application of this therapeutic concept. PMID:22040774

  19. The availability of community ties predicts likelihood of peer referral for mammography: geographic constraints on viral marketing.

    PubMed

    Southwell, Brian G; Slater, Jonathan S; Rothman, Alexander J; Friedenberg, Laura M; Allison, Tiffany R; Nelson, Christina L

    2010-11-01

    Engaging social networks to encourage preventive health behavior offers a supplement to conventional mass media campaigns and yet we do not fully understand the conditions that facilitate or hamper such interpersonal diffusion. One set of factors that should affect the diffusion of health campaign information involves a person's community. Variables describing geographic communities should predict the likelihood of residents accepting campaign invitations to pass along information to friends, family, and others. We investigate two aspects of a community--the availability of community ties and residential stability--as potential influences on diffusion of publicly-funded breast cancer screening in the United States in 2008-2009. In a survey study of 1515 participants living in 91 zip codes across the State of Minnesota, USA, we focus on the extent to which women refer others when given the opportunity to nominate family, friends, and peers to receive free mammograms. We predicted nomination tendency for a particular zip code would be a function of available community ties, measured as religious congregation density in that zip code, and also expected the predictive power of available ties would be greatest in communities with relatively high residential stability (meaning lower turnover in home residence). Results support our hypotheses. Congregation density positively predicted nomination tendency both in bivariate analysis and in Tobit regression models, and was most predictive in zip codes above the median in residential stability. We conclude that having a local infrastructure of social ties available in a community predicts the diffusion of available health care services in that community. PMID:20864236

  20. The formation and maintenance of single-thread tie channels entering floodplain lakes: observations from three diverse river systems

    SciTech Connect

    Rowland, Joel C; Dietrich, William E; Day, Geoff; Parker, Gary

    2009-01-01

    Tie channels connect rivers to floodplain lakes on many lowland rivers and thereby play a central role in floodplain sedimentology and ecology, yet they are generally unrecognized and little studied. here we report the results of field studies focused on tie channel origin and morphodynamics in three contrasting systems: the Middle Fly River, Papua New Guinea, the Lower Mississippi River, and Birch Creek in Alaska. Across these river systems, tie channels vary by an order of magnitude in size but exhibit the same characteristic morphology and appear to develop and evolve by a similar set of processes. In all three systems, the channels are characterized by a narrow, leveed single-thread morphology with maximum width approximately one tenth the width of the mainstem river. The channels typically have a V shaped cross-section, unlike most fluvial channels. These channels develop as lakes become isolated from the river by sedimentation. Narrowing of the connection between river and lake causes a sediment-laden jet to develop. Levees develop along the margins of the jet leading to channel emergence and eventual levee aggradation to the height of the mainstem levees. Bi-directional flow in these channels is common. Outflows from the lake scour sediment and prevent channel blockage. We propose that channel geometry and size are then controlled by a dynamic balance between channel narrowing by suspended sediment deposition and incision and widening by mass failure of banks during outflows. Tie channels are laterally stable and may convey flow for hundreds to a few thousand of years.

  1. Applications of carboxylesterase activity in environmental monitoring and toxicity identification evaluations (TIEs).

    PubMed

    Wheelock, Craig E; Phillips, Bryn M; Anderson, Brian S; Miller, Jeff L; Miller, Mike J; Hammock, Bruce D

    2008-01-01

    This review has examined a number of issues surrounding the use of carboxylesterase activity in environmental monitoring. It is clear that carboxylesterases are important enzymes that deserve increased study. This class of enzymes appears to have promise for employment in environmental monitoring with a number of organisms and testing scenarios, and it is appropriate for inclusion in standard monitoring assays. Given the ease of most activity assays, it is logical to report carboxylesterase activity levels as well as other esterases (e.g., acetylcholinesterase). Although it is still unclear as to whether acetylcholinesterase or carboxylesterase is the most "appropriate" biomarker, there are sufficient data to suggest that at the very least further studies should be performed with carboxylesterases. Most likely, data will show that it is optimal to measure activity for both enzymes whenever possible. Acetylcholinesterase has the distinct advantage of a clear biological function, whereas the endogenous role of carboxylesterases is still unclear. However, a combination of activity measurements for the two enzyme systems will provide a much more detailed picture of organism health and insecticide exposure. The main outstanding issues are the choice of substrate for activity assays and which tissues/organisms are most appropriate for monitoring studies. Substrate choice is very important, because carboxylesterase activity consists of multiple isozymes that most likely fluctuate on an organism- and tissue-specific basis. It is therefore difficult to compare work in one organism with a specific substrate with work performed in a different organism with a different substrate. An attempt should therefore be made to standardize the method. The most logical choice is PNPA (p-nitrophenyl acetate), as this substrate is commercially available, requires inexpensive optics for assay measurements, and has been used extensively in the literature. However, none of these beneficial properties indicates that the substrate is an appropriate surrogate for a specific compound, e.g., pyrethroid-hydrolyzing activity. It will most likely be necessary to have more specific surrogate substrates for use in assays that require information on the ability to detoxify/hydrolyze specific environmental contaminants. The use of carboxylesterase activity in TIE protocols appears to have excellent promise, but there are further technical issues that should be addressed to increase the utility of the method. The main concerns include the large amount of nonspecific protein added to the testing system, which can lead to undesirable side effects including nonspecific reductions in observed toxicity, decrease in dissolved oxygen content, and organism growth. It is probable that these issues can be resolved with further assay development. The ideal solution would be to have a commercial recombinant carboxylesterase that possessed elevated pyrethroid-hydrolysis activity and which was readily available, homogeneous, and inexpensive. The availability of such an enzyme would address nearly all the current method shortcomings. Such a preparation would be extremely useful for the aquatic toxicology community. Further work should focus on screening available esterases for stability, cost, and activity on pyrethroids, with specific focus on esterases capable of distinguishing type I from type II pyrethroids. It would also be beneficial to identify esterases that are not sensitive to OP insecticides. Many esterases and lipases are available as sets to test chemical reactions for green chemistry, enabling large-scale screening. Other potential approaches to increase the utility of the enzyme include derivatization with polyethylene glycol (PEG) or cyanuric acid chloride to increase stability and reduce microbial degradation. It is also possible that the enzyme could be formulated in a sol gel preparation to increase stability. It is likely that the use of carboxylesterase addition will increase for applications in sediment TIEs. Carboxylesterases are an interestin

  2. Amigos and Amistades: The role of men’s social network ties in shaping HIV vulnerability in the Dominican Republic

    PubMed Central

    Fleming, Paul J.; Barrington, Clare; Perez, Martha; Donastorg, Yeycy; Kerrigan, Deanna

    2014-01-01

    While men’s social networks have been identified as a source of influence on sexual behaviour, less is known about the different types of friendship ties within men’s networks. We analysed data from qualitative in-depth interviews with 36 men in Santo Domingo, Dominican Republic who were current or former sexual partners of female sex workers to understand how a) men describe trust and communication with different types of friendship ties, b) characteristics of trust and communication reflect norms of masculinity, and c) these friendship ties influence HIV-related behaviours. We identified a distinction between amistades, social drinking buddies who are not trusted, and amigos, trusted friends. The majority of men lacked any amigos and some had neither amigos nor amistades. In general, men reflected traditional norms of masculinity and said they did not feel they could discuss their relationships or emotional topics with other men. Trust and communication dynamics, and how norms of masculinity shape those dynamics, should be understood and addressed in the design of HIV prevention efforts with men’s social networks as they have implications for the potential effectiveness of such efforts. PMID:24939001

  3. Improvement of the Accuracy of InSAR Image Co-Registration Based On Tie Points – A Review

    PubMed Central

    Zou, Weibao; Li, Yan; Li, Zhilin; Ding, Xiaoli

    2009-01-01

    Interferometric Synthetic Aperture Radar (InSAR) is a new measurement technology, making use of the phase information contained in the Synthetic Aperture Radar (SAR) images. InSAR has been recognized as a potential tool for the generation of digital elevation models (DEMs) and the measurement of ground surface deformations. However, many critical factors affect the quality of InSAR data and limit its applications. One of the factors is InSAR data processing, which consists of image co-registration, interferogram generation, phase unwrapping and geocoding. The co-registration of InSAR images is the first step and dramatically influences the accuracy of InSAR products. In this paper, the principle and processing procedures of InSAR techniques are reviewed. One of important factors, tie points, to be considered in the improvement of the accuracy of InSAR image co-registration are emphatically reviewed, such as interval of tie points, extraction of feature points, window size for tie point matching and the measurement for the quality of an interferogram. PMID:22399966

  4. Pharmacophore modeling studies of type I and type II kinase inhibitors of Tie2.

    PubMed

    Xie, Qing-Qing; Xie, Huan-Zhang; Ren, Ji-Xia; Li, Lin-Li; Yang, Sheng-Yong

    2009-02-01

    In this study, chemical feature based pharmacophore models of type I and type II kinase inhibitors of Tie2 have been developed with the aid of HipHop and HypoRefine modules within Catalyst program package. The best HipHop pharmacophore model Hypo1_I for type I kinase inhibitors contains one hydrogen-bond acceptor, one hydrogen-bond donor, one general hydrophobic, one hydrophobic aromatic, and one ring aromatic feature. And the best HypoRefine model Hypo1_II for type II kinase inhibitors, which was characterized by the best correlation coefficient (0.976032) and the lowest RMSD (0.74204), consists of two hydrogen-bond donors, one hydrophobic aromatic, and two general hydrophobic features, as well as two excluded volumes. These pharmacophore models have been validated by using either or both test set and cross validation methods, which shows that both the Hypo1_I and Hypo1_II have a good predictive ability. The space arrangements of the pharmacophore features in Hypo1_II are consistent with the locations of the three portions making up a typical type II kinase inhibitor, namely, the portion occupying the ATP binding region (ATP-binding-region portion, AP), that occupying the hydrophobic region (hydrophobic-region portion, HP), and that linking AP and HP (bridge portion, BP). Our study also reveals that the ATP-binding-region portion of the type II kinase inhibitors plays an important role to the bioactivity of the type II kinase inhibitors. Structural modifications on this portion should be helpful to further improve the inhibitory potency of type II kinase inhibitors. PMID:19138543

  5. System identification of a tied arch bridge using reference-based wireless sensor networks

    NASA Astrophysics Data System (ADS)

    Hietbrink, Colby; Whelan, Matthew J.

    2012-04-01

    Vibration-based methods of structural health monitoring are generally founded on the principle that localized damage to a structure would exhibit changes within the global dynamic response. Upon this basis, accelerometers provide a unique health monitoring strategy in that a distributed network of sensors provides the technical feasibility to isolate the onset of damage without requiring that any sensor be located exactly on or in close proximity to the damage. While in theory this may be sufficient, practical experience has shown significant improvement in the application of damage diagnostic routines when mode shapes characterized by strongly localized behavior of specific elements are captured by the instrumentation array. In traditional applications, this presents a challenge since the cost and complexity of cable-based systems often effectively limits the number of instrumented locations thereby constraining the modal parameter extraction to only global modal responses. The advent of the low-cost RF chip transceiver with wireless networking capabilities has afforded a means by which a substantial number of output locations can be measured through referencebased testing using large-scale wireless sensor networks. In the current study, this approach was applied to the Prairie du Chien Bridge over the Mississippi River to extract operational mode shapes with high spatial reconstruction, including strongly localized modes. The tied arch bridge was instrumented at over 230 locations with single-axis accelerometers conditioned and acquired over a high-rate lossless wireless sensor network with simultaneous sampling capabilities. Acquisition of the dynamic response of the web plates of the arch rib was specifically targeted within the instrumentation array for diagnostic purposes. Reference-based operational modal analysis of the full structure through data-driven stochastic subspace identification is presented alongside finite element analysis results for confirmation of modal parameter plausibility. Particular emphasis is placed on the identification and reconstruction of modal response with large contribution from the arch rib web plates.

  6. Energy Transmission and Infrastructure

    SciTech Connect

    Mathison, Jane

    2012-12-31

    The objective of Energy Transmission and Infrastructure Northern Ohio (OH) was to lay the conceptual and analytical foundation for an energy economy in northern Ohio that will: • improve the efficiency with which energy is used in the residential, commercial, industrial, agricultural, and transportation sectors for Oberlin, Ohio as a district-wide model for Congressional District OH-09; • identify the potential to deploy wind and solar technologies and the most effective configuration for the regional energy system (i.e., the ratio of distributed or centralized power generation); • analyze the potential within the district to utilize farm wastes to produce biofuels; • enhance long-term energy security by identifying ways to deploy local resources and building Ohio-based enterprises; • identify the policy, regulatory, and financial barriers impeding development of a new energy system; and • improve energy infrastructure within Congressional District OH-09. This objective of laying the foundation for a renewable energy system in Ohio was achieved through four primary areas of activity: 1. district-wide energy infrastructure assessments and alternative-energy transmission studies; 2. energy infrastructure improvement projects undertaken by American Municipal Power (AMP) affiliates in the northern Ohio communities of Elmore, Oak Harbor, and Wellington; 3. Oberlin, OH-area energy assessment initiatives; and 4. a district-wide conference held in September 2011 to disseminate year-one findings. The grant supported 17 research studies by leading energy, policy, and financial specialists, including studies on: current energy use in the district and the Oberlin area; regional potential for energy generation from renewable sources such as solar power, wind, and farm-waste; energy and transportation strategies for transitioning the City of Oberlin entirely to renewable resources and considering pedestrians, bicyclists, and public transportation as well as drivers in developing transportation policies; energy audits and efficiency studies for Oberlin-area businesses and Oberlin College; identification of barriers to residential energy efficiency and development of programming to remove these barriers; mapping of the solar-photovoltaic and wind-energy supply chains in northwest Ohio; and opportunities for vehicle sharing and collaboration among the ten organizations in Lorain County from the private, government, non-profit, and educational sectors. With non-grant funds, organizations have begun or completed projects that drew on the findings of the studies, including: creation of a residential energy-efficiency program for the Oberlin community; installation of energy-efficient lighting in Oberlin College facilities; and development by the City of Oberlin and Oberlin College of a 2.27 megawatt solar photovoltaic facility that is expected to produce 3,000 megawatt-hours of renewable energy annually, 12% of the College’s yearly power needs. Implementation of these and other projects is evidence of the economic feasibility and technical effectiveness of grant-supported studies, and additional projects are expected to advance to implementation in the coming years. The public has benefited through improved energydelivery systems and reduced energy use for street lighting in Elmore, Oak Harbor, and Wellington; new opportunities for assistance and incentives for residential energy efficiency in the Oberlin community; new opportunities for financial and energy savings through vehicle collaboration within Lorain County; and decreased reliance on fossil fuels and expanded production of renewable energy in the region. The dissemination conference and the summary report developed for the conference also benefited the public, but making the findings and recommendations of the regional studies broadly available to elected officials, city managers, educators, representatives of the private sector, and the general public.

  7. [Recent advances in transmissible tumors].

    PubMed

    Tingting, Yin; Lu, Wang; Guodong, Wang

    2015-11-01

    Transmissible tumors are a class of tumor that can be transmitted between individuals through living cells. So far, four types of transmissible tumors including canine transmissible venereal tumor (CTVT),Tasmanian devil facial tumor disease (DFTD), soft-shell clams leukemia (SSCL), and hamsters reticulum cell sarcoma (HRCS)have been discovered and identified. In the last decades, these transmissible tumors have been proved to be transmitted through living cells by cytological, histological and genetic studies. CTVT, the oldest mammalian somatic cell line, and DFTD originated from Schwann cell have been reported to avoid immunological recognition by down-regulating MHC expression, while a high copy number of Steamer retrotransposon is commonly exist in SSCL. In recent years, the whole-genome sequencing of CTVT and DFTD have been completed which facilitates studies on the mechanisms of tumorigenesis, transmission and evolution of transmissible tumors at the whole-genome level. In this review, we summarize the recent advances in transmissible tumors and discuss the research focus in next decade. PMID:26582522

  8. Transmission gearing arrangement

    SciTech Connect

    Klemen, D.

    1987-08-04

    A gearing arrangement is described for an automotive power transmission comprising: an input shaft and an output shaft; first, second, and third simple planetary gear sets. Each has a sun gear, a ring gear, and a planet gears meshing with the sun and the ring gears and rotatably supported on a planet carrier; means rigidly interconnecting the ring gear of the third gear set and the carrier of the second gear set; means rigidly interconnecting the ring gear of the second gear set and the carrier of the first gear set; means rigidly connecting the output shaft and the carrier of the third gear set; a first intermediate shaft rigidly interconnecting the sun gears of the second and the third gear sets for unitary rotation; a second intermediate shaft rigidly connected to the carrier of the second gear set; a third intermediate shaft continuously connected to the input shaft and to the sun gear of the first gear set; first, second, and third brake means operative to selectively brake rotation of the ring gears of the first, the second, and the third gear sets, respectively; a first rotating clutch selectively operable to connect the input shaft and the first intermediate shaft for unitary rotation; a second rotating clutch selectively operable to connect the input shaft and the second intermediate shaft for unitary rotation; a fourth simple planetary gear set including a sun gear and a ring gear and planet gears meshing with the sun and the ring gears and rotatably supported on a planet carrier; means rigidly connecting the sun gear of the fourth gear set to the third intermediate shaft; means rigidly connecting the ring gear of the fourth gear set to the carrier of the first gear set; and a fourth brake means selectively operable to brake the carrier of the fourth gear set. The nine forward ratios are obtainable while preserving a single transition shifting over the entire nine forward ratios.

  9. Multistate differential transmission

    SciTech Connect

    Whalen, B.L.

    1989-05-30

    This patent describes a multistate transmission suitable for a colinear configuration having a stationary housing and an input shaft and an output shaft comprising: a first pair of planetary gear trains comprising a first common ring gear having a torque reducing gear train consisting of a sun gear and a planetary gears connected by way of a carrier to the output shaft and a reversing planetary gear train consisting of a sun gear and planetary gears; a second pair of planetary a trains comprising a second common ring gear having a torque reducing gear train consisting of a sun gear and planetary gears connected by way of a carrier to the sun gear in the reversing planetary gear train in the first pair of planetary gear trains and a reversing planetary gear train consisting of a sun gear and planetary gears; carrier means connecting the sun gears in the first pair of planetary gear trains to the housing through a free wheeling clutch to provide for rotation in one direction only and to one side of a first operational clutch. The other side of the clutch is connected to the sun gear in the reversing planetary gear train in the first pair of planetary gear trains; means connecting the planetary gears in the reversing mechanism of the second pair of planetary gear trains to the housing through a second operational clutch and to one side of a third operational clutch. The other side of the third operational clutch is connected to the sun gear in the reversing planetary gear grain in the second pair of planetary gear trains.

  10. 76 FR 49841 - Transmission Planning and Cost Allocation by Transmission Owning and Operating Public Utilities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ...Independent Transmission Group points to the Trans Bay Cable, Neptune, and Cross Sound Cable transmission projects, which were...Transmission Group, had significant cost overruns, and that the Neptune and Cross Sound Cable transmission projects were merchant...

  11. Transmission Line Series Compensation for Wind Energy Transmission

    NASA Astrophysics Data System (ADS)

    Palanichamy, Dr C., Prof; Wong, Y. C.

    2015-04-01

    Wind energy has demonstrated to be a clean, copious and absolutely renewable source of energy, and the large penetration of it into the power grid indicates that wind energy is considered an effective means of power generation, Transmission of wind energy from remote locations to load centers necessitates long transmission lines. Series compensation is a proven and economical transmission solution to address system power transfer strength, grid stability, and voltage profile issues of long transmission lines. In this paper, a programmable approach to determine the capacitive reactance of series capacitor and optimum location for its placement to achieve maximum power transfer gas been presented. The respective program with sample solutions has been provided for real-time applications.

  12. Electrical transmission line diametrical retainer

    DOEpatents

    Hall, David R. (Provo, UT); Hall, Jr., H. Tracy (Provo, UT); Pixton, David (Lehi, UT); Dahlgren, Scott (Provo, UT); Sneddon, Cameron (Provo, UT); Briscoe, Michael (Lehi, UT); Fox, Joe (Spanish Fork, UT)

    2004-12-14

    The invention is a mechanism for retaining an electrical transmission line. In one embodiment of the invention it is a system for retaining an electrical transmission line within down hole components. In accordance with one aspect of the invention, the system includes a plurality of downhole components, such as sections of pipe in a drill string. The system also includes a coaxial cable running between the first and second end of a drill pipe, the coaxial cable having a conductive tube and a conductive core within it. The invention allows the electrical transmission line to with stand the tension and compression of drill pipe during routine drilling cycles.

  13. Midwest Transmission Workshop I Summary

    SciTech Connect

    Kevin Bryan

    2001-05-01

    OAK-B135 The meeting was opened with a review of the purposes of the workshop: (1) Present and discuss key studies and assessments of transmission upgrades, additions and related issues for the upper Midwest, including work that addresses the full range of views on these topics; (2) Understand the various transmission issues in the upper Midwest and discuss options for addressing the issues; and (3) Identify the decision makers and entities that need to play an active role if transmission issues are to be resolved, and agree on next steps for engaging these individuals and organizations through education, outreach, and information dissemination.

  14. Intertwined arbovirus transmission activity: reassessing the transmission cycle paradigm

    PubMed Central

    Diaz, Luis A.; Flores, Fernando S.; Quaglia, Agustín; Contigiani, Marta S.

    2013-01-01

    Arboviruses are emerging/reemerging infectious agents worldwide. The factors within this scenario include vector and host population fluctuations, climatic changes, anthropogenic activities that disturb ecosystems, an increase in international flights, human mobility, and genetic mutations that allow spill-over phenomenon. Arboviruses are maintained by biologic transmission among vectors and hosts. Sometimes this biological transmission is specific and includes one vector and host species such as Chikungunya (CHIKV), Dengue (DENV), and urban Yellow Fever (YFV). However, most of the arboviruses are generalist and they use many vectors and hosts species. From this perspective, arboviruses are maintained through a transmission network rather than a transmission cycle. This allows us to understand the complexity and dynamics of the transmission and maintenance of arboviruses in the ecosystems. The old perspective that arboviruses are maintained in close and stable transmission cycles should be modified by a new more integrative and dynamic idea, representing the real scenario where biological interactions have a much broader representation, indicating the constant adaptability of the biological entities. PMID:23335900

  15. Characterization of Cracking and Crack Growth Properties of the C5A Aircraft Tie-Box Forging

    NASA Technical Reports Server (NTRS)

    Piascik, Robert S.; Smith, Stephen W.; Newman, John A.; Willard, Scott A.

    2003-01-01

    Detailed destructive examinations were conducted to characterize the integrity and material properties of two aluminum alloy (7075-T6) horizontal stabilizer tie box forgings removed.from US. Air Force C5A and C5B transport aircraft. The C5B tie box forging was,found to contain no evidence of cracking. Thirteen cracks were found in the CSA,forging. All but one of the cracks observed in the C5A component were located along the top cap region (one crack was located in the bottom cap region). The cracks in the C5A component initiated at fastener holes and propagated along a highly tunneled intergranular crack path. The tunneled crack growth configuration is a likelv result of surface compressive stress produced during peening of the .forging suijace. The tie box forging ,fatigue crack growth, fracture and stress corrosion cracking (SCC) properties were characterized. Reported herein are the results of laboratory air ,fatigue crack growth tests and 95% relative humidity SCC tests conducted using specimens machined from the C5A ,forging. SCC test results revealed that the C5A ,forging material was susceptible to intergranular environmental assisted cracking: the C5A forging material exhibited a SCC crack-tip stress-intensity factor threshold of less than 6 MPadn. Fracture toughness tests revealed that the C5A forging material exhibited a fracture toughness that was 25% less than the C5B forging. The C5A forging exhibited rapid laboratory air fatigue crack growth rates having a threshold crack-tip stress-intensity factor range of less than 0.8 MPa sup m. Detailed fractographic examinations revealed that the ,fatigue crack intergranular growth crack path was similar to the cracking observed in the C5A tie box forging. Because both fatigue crack propagation and SCC exhibit similar intergranular crack path behavior, the damage mechanism resulting in multi-site cracking of tie box forgings cannot be determined unless local cyclic stresses can be quantified.

  16. 78 FR 30804 - Transmission Planning Reliability Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ...the currently-effective Transmission Planning Reliability Standards...footnote 12 ``allow[s] for transmission planners to plan for non...assessment of backup or redundant protection systems, and...12 within the Near-Term Transmission Planning Horizon to...

  17. Keep Your Friends Close and Your Facebook Friends Closer: A Multiplex Network Approach to the Analysis of Offline and Online Social Ties

    E-print Network

    Hristova, Desislava; Mascolo, Cecilia

    2014-01-01

    Social media allow for an unprecedented amount of interaction between people online. A fundamental aspect of human social behavior, however, is the tendency of people to associate themselves with like-minded individuals, forming homogeneous social circles both online and offline. In this work, we apply a new model that allows us to distinguish between social ties of varying strength, and to observe evidence of homophily with regards to politics, music, health, residential sector & year in college, within the online and offline social network of 74 college students. We present a multiplex network approach to social tie strength, here applied to mobile communication data - calls, text messages, and co-location, allowing us to dimensionally identify relationships by considering the number of communication channels utilized between students. We find that strong social ties are characterized by maximal use of communication channels, while weak ties by minimal use. We are able to identify 75% of close friendshi...

  18. Video transmission over wireless networks 

    E-print Network

    Zhao, Shengjie

    2005-08-29

    Compressed video bitstream transmissions over wireless networks are addressed in this work. We first consider error control and power allocation for transmitting wireless video over CDMA networks in conjunction with multiuser detection. We map a...

  19. RICE UNIVERSITY BEAMSWITCH: DIRECTIONAL TRANSMISSION

    E-print Network

    Zhong, Lin

    RICE UNIVERSITY BEAMSWITCH: DIRECTIONAL TRANSMISSION FOR ENERGY-EFFICIENT WIRELESS COMMUNICATION guidance and support throughout my research and study at Rice. This work would not be possible without his

  20. Automatic transmission for electric wheelchairs.

    PubMed

    Reswick, J B

    1985-07-01

    A new infinitely variable automatic transmission called the RESATRAN that automatically changes its speed ratio in response to load torque being transmitted is presented. A prototype has been built and tested on a conventional three-wheeled electric motor propelled wheelchair. It is shown theoretically that more than 50 percent reduction in power during hill climbing may be expected when a transmission-equipped wheelchair is compared to a direct-drive vehicle operating at the same voltage. It is suggested that with such a transmission, wheelchairs can use much smaller motors and associated electronic controls, while at the same time gaining in efficiency that results in longer operating distances for the same battery charge. Design details of the transmission and test results are presented. These results show a substantial reduction in operating current and increased distance of operation over a test course. PMID:3835264

  1. Data routing and transmission protocols

    E-print Network

    Wood, Lloyd

    1 Data routing and transmission protocols Dr Lloyd Wood Global Defense, Space and Security, Cisco Systems http://www.cisco.com/go/space DARPA Fractionated Spacecraft Workshop, Colorado Springs, 3 August

  2. Hybrid-Vehicle Transmission System

    NASA Technical Reports Server (NTRS)

    Lupo, G.; Dotti, G.

    1985-01-01

    Continuously-variable transmission system for hybrid vehicles couples internal-combustion engine and electric motor section, either individually or in parallel, to power vehicle wheels during steering and braking.

  3. Transmission systems undergo major changes

    SciTech Connect

    Beaty, W.

    1995-03-01

    Siting and construction of new transmission facilities has become very complex and difficult because of concerns about property values, visual impacts, electric and magnetic fields, open access and a host of other problems. Despite the difficulties, new facilities will need to be built to supply new loads and the increasing demand from customers for reliable electric service. A research project to determine and understand public perception of transmission lines and substations is underway which could be extremely valuable for utilities. The ultimate goal of the research project is to develop an empirically based understanding of the public`s perceptions of transmission and substations that can be used to develop guidelines for improved transmission project planning, siting, design, and impact assessment. These findings will be translated into guidelines for: substation planning, siting and design; public involvement program development; and, tolls for pre-project assessments of potential human impacts.

  4. Wavelength multiplexing for information transmission

    NASA Astrophysics Data System (ADS)

    Bartelt, H. O.

    1978-12-01

    Optical information depends normally on one or two dimensions. A parallel transmission through a zero-dimentional fiber therefore needs a suitable coding. For an achromatric grey level object this can be achieved by the use of wavelength multiplexing. The information of each position in the original object is carried by a different wavelength. Simple dispersive elements perform the encoding and decoding process. Application examples are shown for the transmission of bar codes and paper tape data.

  5. Diversified transmission multichannel detection system

    SciTech Connect

    Tournois, P.; Engelhard, P.

    1984-07-03

    A detection system for imaging by sonar or radar signals. The system associates diversified transmissions with an interferometric base. This base provides an angular channel formation means and each signal formed in this way is processed by matched filtering in a circuit containing copy signals characterizing the space coloring obtained by the diversified transmission means. The invention is particularly applicable to side or front looking detection sonars.

  6. Free-Space Power Transmission

    NASA Technical Reports Server (NTRS)

    1989-01-01

    NASA Lewis Research Center organized a workshop on technology availability for free-space power transmission (beam power). This document contains a collection of viewgraph presentations that describes the effort by academia, industry, and the national laboratories in the area of high-frequency, high-power technology applicable to free-space power transmission systems. The areas covered were rectenna technology, high-frequency, high-power generation (gyrotrons, solar pumped lasers, and free electron lasers), and antenna technology.

  7. Advanced Rotorcraft Transmission (ART) program

    NASA Technical Reports Server (NTRS)

    Heath, Gregory F.; Bossler, Robert B., Jr.

    1993-01-01

    Work performed by the McDonnell Douglas Helicopter Company and Lucas Western, Inc. within the U.S. Army/NASA Advanced Rotorcraft Transmission (ART) Program is summarized. The design of a 5000 horsepower transmission for a next generation advanced attack helicopter is described. Government goals for the program were to define technology and detail design the ART to meet, as a minimum, a weight reduction of 25 percent, an internal noise reduction of 10 dB plus a mean-time-between-removal (MTBR) of 5000 hours compared to a state-of-the-art baseline transmission. The split-torque transmission developed using face gears achieved a 40 percent weight reduction, a 9.6 dB noise reduction and a 5270 hour MTBR in meeting or exceeding the above goals. Aircraft mission performance and cost improvements resulting from installation of the ART would include a 17 to 22 percent improvement in loss-exchange ratio during combat, a 22 percent improvement in mean-time-between-failure, a transmission acquisition cost savings of 23 percent of $165K, per unit, and an average transmission direct operating cost savings of 33 percent, or $24K per flight hour. Face gear tests performed successfully at NASA Lewis are summarized. Also, program results of advanced material tooth scoring tests, single tooth bending tests, Charpy impact energy tests, compact tension fracture toughness tests and tensile strength tests are summarized.

  8. Essays on electricity transmission investment and financial transmission rights

    NASA Astrophysics Data System (ADS)

    Shang, Wenzhuo

    The U.S. electric power industry has been going through fundamental restructuring and realignment since the 1990's. Many issues and problems have emerged during the transition, and both economists and engineers have been looking for the solutions fervently. In this dissertation, which consists primarily of three essays, we apply economics theory and techniques to the power industry and address two related issues, transmission investment and financial transmission rights (FTRs). The first essay takes the decentralized perspective and investigates the efficiency attribute of market-based transmission investment under perfect competition. We clarify, for the first time, the nature of the externality created by loop flows that causes transmission investment to be inefficient. Our findings have important implications for better understanding of transmission market design and creating incentives for efficient transmission investment. In the second essay, we define several rules for allocating transmission investment cost within the framework of cooperative game theory. These rules provide fair, stable or efficient cost allocations in theory and are good benchmarks against which the allocation mechanism in practice can be compared and improved upon. In the last essay, we make exploratory efforts in analyzing and assessing empirically the performance of the Midwest independent system operator (MISO) FTR auction market. We reveal some stylized facts about this young market and find that it is not efficient under the risk-neutrality assumption. We also point out and correct the drawbacks in previous related work and suggest about more complete empirical work in future. In all, this dissertation makes both theoretic and empirical analysis of the two hot issues related to the power industry and comes up with findings that have important implications for the development of this industry.

  9. 2001 GPS and Classical Survey at Medicina Observatory: Local Tie and VLBI Antenna's Reference Point Determination

    NASA Astrophysics Data System (ADS)

    Vittuari, Luca; Sarti, Pierguido; Tomasi, Paolo

    2001-12-01

    During a 6 days campaign in June 2001, we have performed a local survey at Medicina Observatory using classical geodesy and GPS techniques in order to determine the effects of an undergone track repair. We have determined the position of the reference point P within a local and ITRF2000 (epoch 1997.0) reference frames using trilateration and triangulation: Pclas_{loc}^{2001}=(21.580pm0.001,45.536pm0.001,17.699pm0.001) Pclas_{loc}^{2001}=(21.580pm0.001,45.536pm0.001,17.699pm0.001) Pclas_{ITRF2000}^{1997.0}=(4461369.982pm0.001,919596.818pm0.001,4449559.207pm0.001) Kinematic GPS has also given interesting results:tie between the 3-D forced centered local ground control network (materialised in May 2000) and the widely used older network (which is now experiencing some problems due to the disgregation of the concrete where bolts are situated) has also been realised. This will allow inter-comparison of results obtained by the different campaigns that have been carried out in the last decade. Finally, the position of the ASI-GPS permanent station has been estimated within the local ground control network. Thus, using classical methodology, a precise determination of the VLBI-GPS ex-centre vector has been possible.

  10. Radioisotopic Tie Points of the Quaternary Geomagnetic Instability Time Scale (GITS): How Accurate and Precise?

    NASA Astrophysics Data System (ADS)

    Singer, B. S.

    2014-12-01

    Reversals and excursions of the geomagnetic field are recorded globally by sedimentary and volcanic rocks. These geodynamo instabilities provide a rich set of chronostratigraphic tie points for the Quaternary period that can provide tests of age models central to paleoclimate studies. Radioisotopic dating of volcanic rocks, mainly 40Ar/39Ar dating of lava flows, coupled with astronomically-dated deep sea sediments, reveals 10 polarity reversals and 27 field excursions during the Quaternary (Singer, 2014). A key question concerns the uncertainties associated with radioisotopic dates of those geodynamo instabilities that have been identified both in terrestrial volcanic rocks and in deep sea sediments. These particular features offer the highest confidence in linking 40Ar/39Ar dates to the global marine climate record. Geological issues aside, for rocks in which the build-up of 40Ar by decay of 40K may be overwhelmed by atmospheric 40Ar at the time of eruption, the uncertainty in 40Ar/39Ar dates derives from three sources: (1) analytical uncertainty associated with measurement of the isotopes; this is straightforward to estimate; (2) systematic uncertainties stemming from the age of standard minerals, such as the Fish Canyon sanidine, and in the 40K decay constant; and (3) systematic uncertainty introduced during analysis, mainly the size and reproducibility of procedural blanks. Whereas 1 and 2 control the precision of an age determination, 2 and 3 also control accuracy. In parallel with an astronomical calibration of 28.201 Ma for the Fish Canyon sanidine standard, awareness of the importance of procedural blanks, and a new generation multi-collector mass spectrometer capable of exceptionally low-blank and isobar-free analysis, are improving both accuracy and precision of 40Ar/39Ar dates. Results from lavas recording the Matuyama-Brunhes reversal, the Santa Rosa excursion, and the reversal at the top of the Cobb Mtn subchron demonstrate these advances. Current best ages for these instabilities are 777 ± 2, 932 ± 3, and 1189 ± 1 ka (±1?), respectively. These ages, likely accurate and precise to better than ±0.3%, are identical to those determined from deep sea sediment cores for which high-resolution magnetostratigraphy and O isotope-based age models have been developed (Channell et al., 2010).

  11. Strengthening the ties between university and school - Bilingual geography is the future for our multifarious subject

    NASA Astrophysics Data System (ADS)

    Barnikel, F.

    2003-04-01

    An incessantly growing interaction between numerous fields of human activity asks for an open-minded approach and interdisciplinarity. No subject matches geography when it comes to bridging the gaps between different aspects of human life. Geography does not only describe, analyse and explain the "natural" state of the world we live in, it does also connect the disciplines within the physical branch of the subject with disciplines in the human or anthropogenic part, which describes the state of the world "as is". Geography is, therefore, in itself multi-disciplinary. Considering the immense importance of geography as the subject dealing with our environment and facing the fact that it is this environment which is already endangered by the multiple forms of human interference, geography and its multi-disciplinary character deserve even increased attention. The growth of the world's population, future climatic change and shortages of natural resources add to the importance of geography as the one subject in school dealing with these problems. In our societies, which are constantly growing together in political and economic issues, the structures of communication additionally mainly rely on an easily accessible and widely spread language like English to serve the needs of modern international contact. In Bavaria, the signs of the times have been recognized quite early. Nearly 8000 pupils at more than 80 high-level secondary schools ("Gymnasien") attend bilingual teaching, a large part of which is performed in geography. The Adolf-Weber-Gymnasium serves as an example, since it has the largest group of pupils instructed in bilingual geography in Munich. Next term, more than 150 boys and girls from five grades will be taught geography in English. Our goal is, in contrast to concepts of bilingual teaching in some other German states, not only to improve the language capability of our pupils. It is more an investment in scientific propaedeutics. It strenghtens the ties between university and school, since it enables future students to comprehend the character of geography and the aspects of its underlying diversity, and it, consequently, improves the students' ability to understand and solve geographical problems of the future.

  12. Infection transmission science and models.

    PubMed

    Koopman, James S

    2005-12-01

    Infection transmission systems circulate infection through complex contact patterns related to both contact patterns and patterns of factors that affect the risk of transmission given contact. The nonlinear dynamics of infection transmission cause these patterns to make big differences in population infection levels. A science of infection transmission system analysis is needed to focus on those details that affect the control of infection transmission. This science must have a strong theoretical base because there is little chance that a dominantly data based approach not using mechanistic models of transmission will have any predictive value. The theoretical base should be built on linked transmission system models that are focused on making needed inferences for both building the theoretical base and making infection control decisions. The linking of different models is needed for a strategy of inference robustness assessment that is designed to find the model that is simple enough to effectively analyze the transmission system but not so simple that realistic violation of simplifying assumptions will change an inference. Types of models that should be used in such linked analyses include deterministic and stochastic compartmental models, discrete individual models with individual event histories but structured mass action mixing, network models that provide more detail as to who has contact with whom, and intermediate model forms such as correlation models that address some aspects of contact details while preserving the flexibility of deterministic compartmental models to structure mixing and analyze the system. While transmission system science is currently weak in regards both to its data base and its theory base, many things are now coming together that could make this science flourish. On the data side these include greater ability to detect infectious agent sequences in the environment and greater ability to sequence and genetically relate agents identified at different sites in the transmission system. On the theory sides, new model construction and model analysis methods are providing new potential to use the new sources of data. Also new parameter estimation methods provide new potential to combine models and data in effective analytic strategies. PMID:16377860

  13. Determination of the extragalactic-planetary frame tie from joint analysis of radio interferometric and lunar laser ranging measurements

    NASA Technical Reports Server (NTRS)

    Folkner, W. M.; Charlot, P.; Finger, M. H.; Williams, J. G.; Sovers, O. J.; Newhall, XX; Standish, E. M., Jr.

    1994-01-01

    Very Long Baseline Interferometry (VLBI) observations of extragalactic radio sources provide the basis for defining an accurate non-rotating reference frame in terms of angular positions of the sources. Measurements of the distance from the Earth to the Moon and to the inner planets provide the basis for defining an inertial planetary ephemeris reference frame. The relative orientation, or frame tie, between these two reference frames is of interest for combining Earth orientation measurements, for comparing Earth orientation results with theories referred to the mean equator and equinox, and for determining the positions of the planets with respect to the extragalactic reference frame. This work presents an indirect determination of the extragalactic-planetary frame tie from a combined reduction of VLBI and Lunar Laser Ranging (LLR) observations. For this determination, data acquired by LLR tracking stations since 1969 have been analyzed and combined with 14 years of VLBI data acquired by NASA's Deep Space Network since 1978. The frame tie derived from this joint analysis, with an accuracy of 0.003 sec, is the most accurate determination obtained so far. This result, combined with a determination of the mean ecliptic (defined in the rotating sense), shows that the mean equinox of epoch J2000 is offset from the x-axis of the extragalactic frame adopted by the International Earth Rotation Service for astrometric and geodetic applications by 0.078 sec +/- 0.010 sec along the y-direction and y 0.019 sec +/- 0.001 sec. along the z-direction.

  14. Climate change and malaria transmission.

    PubMed

    Lindsay, S W; Birley, M H

    1996-12-01

    There is a consensus among climatologists that our planet is experiencing a progressive rise in surface temperature due to the increased production of "greenhouse" gases. Some of the possible consequences of elevated temperature on malaria transmission are examined in the present review. A simple mathematical model is first used to examine the effect of temperature on the ability of Anopheles maculipennis to transmit vivax malaria. This indicates that small increases in temperature at low temperatures may increase the risk of transmission substantially. This is important, since vulnerable communities, poorly protected by health services, in areas of unstable or no malaria are likely to be at increased risk of future outbreaks. In contrast, areas of stable transmission may be little affected by rising temperature. It is thought that global warming will lead to coastal flooding, changes in precipitation and, indirectly, changes in land use. Just how these changes will effect transmission at a regional level requires an understanding of the ecology of local vectors, since environmental changes which favour malaria transmission in one vector species may reduce it in another. Methods for predicting future changes in malaria in different regions are discussed, highlighting the need for further research in this area. Most importantly, there is a need for researchers to validate the accuracy of the models used for predicting malaria and to confirm the assumptions on which the models are based. PMID:9039269

  15. Potential enhanced ability of giant squid to detect sperm whales is an exaptation tied to their large body size.

    PubMed

    Schmitz, Lars; Motani, Ryosuke; Oufiero, Christopher E; Martin, Christopher H; McGee, Matthew D; Wainwright, Peter C

    2013-01-01

    It has been hypothesized that sperm whale predation is the driver of eye size evolution in giant squid. Given that the eyes of giant squid have the size expected for a squid this big, it is likely that any enhanced ability of giant squid to detect whales is an exaptation tied to their body size. Future studies should target the mechanism behind the evolution of large body size, not eye size. Reconstructions of the evolutionary history of selective regime, eye size, optical performance, and body size will improve the understanding of the evolution of large eyes in large ocean animals. PMID:24127991

  16. Single-frequency, injection-seeded Er:YAG laser based on a bow-tie ring slave resonator

    NASA Astrophysics Data System (ADS)

    Yao, B. Q.; Deng, Yu; Dai, T. Y.; Duan, X. M.; You-Lun, Ju; Wang, Y. Z.

    2015-08-01

    A diode pumped, injection-seeded Q-switched Er:YAG laser at 1645.2 nm is demonstrated. A single frequency Er:YAG monolithic nonplanar ring oscillator (NPRO) laser emitting at 1645.24 nm with a maximum output power of 500 mW is used as a seed laser. The seed laser output is injected into a bow-tie slave laser, obtaining stable single-frequency Q-switched operation of the Er:YAG laser. The maximum single-frequency Q-switched Er:YAG laser output energy is 2.9 mJ at 100 Hz with a pulse duration of 160 ns.

  17. Midwest Transmission Workshop III Summary

    SciTech Connect

    Kevin Bryan

    2003-03-12

    OAK-B135 On March 12-13, 2002, the National Wind Coordinating Committee (NWCC), in cooperation with regional stakeholders, held a two-day workshop: Planning for Electrical Transmission Needs in the Upper Midwest. The workshop was the outgrowth of an effort to develop a forum and process for consideration of transmission options that strives for equitable allocation of benefits and impacts among all affected parties. The goal of this workshop was to provide a catalyst for an enhanced, inclusive process for transmission planning with participation of and acceptance by all affected stakeholders. Participants in the meeting included representatives of state and regional regulatory agencies, utilities and power generators, the wind industry, environmental and landowner interests, and other interested parties (see Attachment A for a list of meeting participants).

  18. Clustering, climate and dengue transmission.

    PubMed

    Junxiong, Pang; Yee-Sin, Leo

    2015-06-01

    Dengue is currently the most rapidly spreading vector-borne disease, with an increasing burden over recent decades. Currently, neither a licensed vaccine nor an effective anti-viral therapy is available, and treatment largely remains supportive. Current vector control strategies to prevent and reduce dengue transmission are neither efficient nor sustainable as long-term interventions. Increased globalization and climate change have been reported to influence dengue transmission. In this article, we reviewed the non-climatic and climatic risk factors which facilitate dengue transmission. Sustainable and effective interventions to reduce the increasing threat from dengue would require the integration of these risk factors into current and future prevention strategies, including dengue vaccination, as well as the continuous support and commitment from the political and environmental stakeholders. PMID:25872683

  19. Prudent behaviour accelerates disease transmission

    E-print Network

    Scarpino, Samuel V; Hebert-Dufresne, Laurent

    2015-01-01

    Infectious diseases often spread faster near their peak than would be predicted given early data on transmission. Despite the commonality of this phenomena, there are no known general mechanisms able to cause an exponentially spreading dis- ease to begin spreading faster. Indeed most features of real world social networks, e.g. clustering1,2 and community structure3, and of human behaviour, e.g. social distancing4 and increased hygiene5, will slow disease spread. Here, we consider a model where individuals with essential societal roles-e.g. teachers, first responders, health-care workers, etc.- who fall ill are replaced with healthy individuals. We refer to this process as relational exchange. Relational exchange is also a behavioural process, but one whose effect on disease transmission is less obvious. By incorporating this behaviour into a dynamic network model, we demonstrate that replacing individuals can accelerate disease transmission. Furthermore, we find that the effects of this process are trivial w...

  20. Remote control apparatus for transmission

    SciTech Connect

    Ebina, A.

    1989-01-10

    A remote control apparatus for a transmission is described, comprising: means for sending a signal representing an operation state of a change lever; auxiliary power means, remote-controlled by the change lever, for changing a gear position of the transmission and sending a signal representing the gear position; and control means for controlling an operation of the auxiliary power means in accordance with the change lever operation state signal and gear position signal, the control means being provided with neutral position holding means comprises signal transmission delay means. This comprises means for detecting that the shift path on which the striker presently exists is different from the shift path instructed according to the change lever operating signal, then detecting that the striker has reached the first neutral position according to the neutral position signal and generating a neutral position detection signal.

  1. Plasmodium vivax Transmission in Africa

    PubMed Central

    Howes, Rosalind E.; Reiner Jr., Robert C.; Battle, Katherine E.; Longbottom, Joshua; Mappin, Bonnie; Ordanovich, Dariya; Tatem, Andrew J.; Drakeley, Chris; Gething, Peter W.; Zimmerman, Peter A.; Smith, David L.; Hay, Simon I.

    2015-01-01

    Malaria in sub-Saharan Africa has historically been almost exclusively attributed to Plasmodium falciparum (Pf). Current diagnostic and surveillance systems in much of sub-Saharan Africa are not designed to identify or report non-Pf human malaria infections accurately, resulting in a dearth of routine epidemiological data about their significance. The high prevalence of Duffy negativity provided a rationale for excluding the possibility of Plasmodium vivax (Pv) transmission. However, review of varied evidence sources including traveller infections, community prevalence surveys, local clinical case reports, entomological and serological studies contradicts this viewpoint. Here, these data reports are weighted in a unified framework to reflect the strength of evidence of indigenous Pv transmission in terms of diagnostic specificity, size of individual reports and corroboration between evidence sources. Direct evidence was reported from 21 of the 47 malaria-endemic countries studied, while 42 countries were attributed with infections of visiting travellers. Overall, moderate to conclusive evidence of transmission was available from 18 countries, distributed across all parts of the continent. Approximately 86.6 million Duffy positive hosts were at risk of infection in Africa in 2015. Analysis of the mechanisms sustaining Pv transmission across this continent of low frequency of susceptible hosts found that reports of Pv prevalence were consistent with transmission being potentially limited to Duffy positive populations. Finally, reports of apparent Duffy-independent transmission are discussed. While Pv is evidently not a major malaria parasite across most of sub-Saharan Africa, the evidence presented here highlights its widespread low-level endemicity. An increased awareness of Pv as a potential malaria parasite, coupled with policy shifts towards species-specific diagnostics and reporting, will allow a robust assessment of the public health significance of Pv, as well as the other neglected non-Pf parasites, which are currently invisible to most public health authorities in Africa, but which can cause severe clinical illness and require specific control interventions. PMID:26587988

  2. Electrical Transmission on the Lunar Surface. Part 1; DC Transmission

    NASA Technical Reports Server (NTRS)

    Gordon, Lloyd B.

    2001-01-01

    This report summarizes a portion of the results from a grant at Auburn University to study the electrical and thermal energy management for lunar facilities. Over the past year (June 1989 to May 1990) the following topics have been investigated: June 1989 to November 1989 - Literature survey, assessment of lunar power needs, and overview study of the requirements of a lunar power system; November 1989 to April 1990 - Develop models for the study of dc electrical power transmission lines for the lunar surface; March 1990 to May 1990 - Develop models for the study of ac electrical power transmission lines for the lunar surface. Because of the large amount of information in the model development and application to a wide parameter space this report is being bound separately. This report specifically contains the model development and parameter study for dc electrical power transmission lines. The end of the funding year (May 1990) will conclude with an annual report including the literature survey, the overview of the requirements of a lunar power system, and summaries of the dc and ac models of electrical transmission lines.

  3. Cluster Transmission Time Synchronization for Cooperative Transmission using Software Defined

    E-print Network

    Ingram, Mary Ann

    Institute of Technology Email: mai@gatech.edu R. Scott Frazier US Department of Defense Email: rscottf the packet for a fixed period before firing. The method has been implemented in an indoor non-line the second hop. I. INTRODUCTION Cooperative transmission (CT) is a technique wherein one or more radios

  4. Intercultural Transmission and Intergenerational Transmission in Immigrant Families.

    ERIC Educational Resources Information Center

    Nauck, Bernhard

    2001-01-01

    Examined the impact of intergenerational transmission processes on the intercultural contact and ethnic identification of second generation adolescents from five migrant groups in Germany, distinguishing four possible outcomes of intercultural contact (integration, assimilation, segregation, and marginalization). Data from interviews with same-sex…

  5. Analytic models for beam propagation and far-field patterns in slab and bow-tie x-ray lasers

    SciTech Connect

    Chandler, E.A.

    1994-06-01

    Simplified analytic models for beam propagation in slab and bow-tie x-ray lasers yield convenient expressions that provide both a framework for guidance in computer modeling and useful approximates for experimenters. In unrefracted bow-tie lasers, the laser shape in conjunction with the nearly-exponential weighting of rays according to their length produces a small effective aperture for the signal. We develop an analytic expression for the aperture and the properties of the far-field signal. Similarly, we develop the view that the far-field pattern of refractive slab lasers is the result of effective apertures that are created by the interplay of refraction and exponential amplification. We present expressions for the size of this aperture as a function of laser parameters as well as for the intensity and position of the far-field lineout. This analysis also yields conditions for the refraction limit in slab lasers and an estimate for the signal loss due to refraction.

  6. School context, friendship ties and adolescent mental health: A multilevel analysis of the Korean Youth Panel Survey (KYPS).

    PubMed

    Kim, Harris Hyun-Soo

    2015-11-01

    Research on the social determinants of health suggests that interpersonal networks play a critical role in facilitating individual mental and physical well-being. Prior studies also indicate that ecological or contextual factors contribute to positive health outcomes. This study extends prior research by examining the factors associated with adolescent health in an Asian context. Based on the multilevel analysis of the Korean Youth Panel Survey (2006 & 2007), a longitudinal project funded by the Korean government, it investigates some of the key variables related to the mental health of Korean students. Much of previous research focuses on the functions of social capital. This study contributes to the social epidemiology literature by investigating the possible downside of network ties. Specifically, it asks whether having delinquent friends is associated with negative mental health experiences. In addition, little research has been conducted concerning the associations between adolescent health outcomes and school characteristics. This study moves in that direction by examining the relationship between mental well-being of students and a variety of school related variables (e.g., subjective attitude toward school and quality of relationship with peers and teachers). Hierarchical linear modeling shows that, among the social capital control variables, being properly integrated into the family and frequent peer interaction significantly add to mental health. At the individual (student) level only, ties to delinquent friends are negatively associated with mental health, while at both individual and contextual levels, school characteristics are positively related to adolescent subjective well-being. PMID:25960374

  7. Flux-based classification of reactions reveals a functional bow-tie organization of complex metabolic networks.

    PubMed

    Singh, Shalini; Samal, Areejit; Giri, Varun; Krishna, Sandeep; Raghuram, Nandula; Jain, Sanjay

    2013-05-01

    Unraveling the structure of complex biological networks and relating it to their functional role is an important task in systems biology. Here we attempt to characterize the functional organization of the large-scale metabolic networks of three microorganisms. We apply flux balance analysis to study the optimal growth states of these organisms in different environments. By investigating the differential usage of reactions across flux patterns for different environments, we observe a striking bimodal distribution in the activity of reactions. Motivated by this, we propose a simple algorithm to decompose the metabolic network into three subnetworks. It turns out that our reaction classifier, which is blind to the biochemical role of pathways, leads to three functionally relevant subnetworks that correspond to input, output, and intermediate parts of the metabolic network with distinct structural characteristics. Our decomposition method unveils a functional bow-tie organization of metabolic networks that is different from the bow-tie structure determined by graph-theoretic methods that do not incorporate functionality. PMID:23767567

  8. Challenges for using quantitative PCR test batteries as a TIE-type approach to identify metal exposure in benthic invertebrates.

    PubMed

    Hook, Sharon E; Osborn, Hannah L; Spadaro, David A; Simpson, Stuart L

    2015-11-01

    The epibenthic amphipod Melita plumulosa shows unique gene expression profiles when exposed to different contaminants. We hypothesized that specific changes in transcript abundance could be used in a battery of quantitative polymerase chain reaction (qPCR) assays as a toxicity identification evaluation (TIE)-like approach to identify the most relevant stressor in field-contaminated sediments. To test this hypothesis, seven candidate transcriptomic markers were selected, and their specificity following metal exposure was confirmed. The performance of these markers across different levels of added metals was verified. The ability of these transcripts to act as markers was tested by exposing amphipods to metal-contaminated field-collected sediments and measuring changes in transcript abundance via qPCR. For two of the three sediments tested, at least some of the transcriptomic patterns matched our predictions, suggesting that they would be effective in helping to identify metal exposure in field sediments. However, following exposure to the third sediment, transcriptomic patterns were unlike our predictions. These results suggest that the seven transcripts may be insufficient to discern individual contaminants from complex mixtures and that microarray or RNA-Seq global gene expression profiles may be more effective for TIE. Changes in transcriptomics based on laboratory exposures to single compounds should be carefully validated before the results are used to analyze mixtures. PMID:24994105

  9. Homies with aspirations and positive peer network ties: associations with reduced frequent substance use among gang-affiliated Latino youth.

    PubMed

    van Dommelen-Gonzalez, Evan; Deardorff, Julianna; Herd, Denise; Minnis, Alexandra M

    2015-04-01

    In marginalized urban neighborhoods across the USA, Latino youth are disproportionately represented among the growing number of youth gangs. Substance use among gang-involved youth poses both immediate and long-term health risks and can threaten educational engagement, future socioeconomic stability, and desistance. Conventional assessments of gang-affiliated youth and their peer network overlook the possibility that positive peer ties may exist and can foster health promoting behavior norms. Drawing on a positive deviance framework, in this study, we examine the relationship between positive peer network characteristics tied to post-secondary educational aspirations and frequent alcohol and marijuana use among Latino, gang-affiliated youth from a neighborhood in San Francisco. Using generalized estimating equations regression models across 72 peer network clusters (162 youth), we found that having close friends who plan to go to a 4-year college was associated with a lower odds of frequent marijuana and alcohol use (OR 0.27, p?=?0.02; OR 0.29, p?=?0.14, respectively) and that this association persisted when adjusting for risk characteristics (OR 0.19, p?

  10. Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system.

    PubMed

    Tieri, Paolo; Grignolio, Andrea; Zaikin, Alexey; Mishto, Michele; Remondini, Daniel; Castellani, Gastone C; Franceschi, Claudio

    2010-01-01

    Recently, the network paradigm, an application of graph theory to biology, has proven to be a powerful approach to gaining insights into biological complexity, and has catalyzed the advancement of systems biology. In this perspective and focusing on the immune system, we propose here a more comprehensive view to go beyond the concept of network. We start from the concept of degeneracy, one of the most prominent characteristic of biological complexity, defined as the ability of structurally different elements to perform the same function, and we show that degeneracy is highly intertwined with another recently-proposed organizational principle, i.e. 'bow tie architecture'. The simultaneous consideration of concepts such as degeneracy, bow tie architecture and network results in a powerful new interpretative tool that takes into account the constructive role of noise (stochastic fluctuations) and is able to grasp the major characteristics of biological complexity, i.e. the capacity to turn an apparently chaotic and highly dynamic set of signals into functional information. PMID:20701759

  11. Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system

    PubMed Central

    2010-01-01

    Recently, the network paradigm, an application of graph theory to biology, has proven to be a powerful approach to gaining insights into biological complexity, and has catalyzed the advancement of systems biology. In this perspective and focusing on the immune system, we propose here a more comprehensive view to go beyond the concept of network. We start from the concept of degeneracy, one of the most prominent characteristic of biological complexity, defined as the ability of structurally different elements to perform the same function, and we show that degeneracy is highly intertwined with another recently-proposed organizational principle, i.e. 'bow tie architecture'. The simultaneous consideration of concepts such as degeneracy, bow tie architecture and network results in a powerful new interpretative tool that takes into account the constructive role of noise (stochastic fluctuations) and is able to grasp the major characteristics of biological complexity, i.e. the capacity to turn an apparently chaotic and highly dynamic set of signals into functional information. PMID:20701759

  12. Gear assisted continuously variable transmission

    SciTech Connect

    Wittke, E.C.

    1987-07-28

    A transmission system is described comprising: a plurality of power transmission paths; a continuously variable speed ratio transmission in one of the paths having a first input means adapted to be driven by an external prime mover, and a first output means; a first ratio changing mechanism having a second input means adapted to be driven by the prime mover and having a second output means; a second ratio changing mechanism having a third input means adapted to be driven by the prime mover and having a third output means, at least one of the ratio changing mechanisms having a plurality of selective ratios other than zero selectively engageable in a respective path; a compound planetary mechanism including fourth, fifth and sixth input means, and a fourth output means providing an output from the transmission system. The first output means is coupled to the fourth input means, the second output means is coupled to the fifth input means, and the third output means is coupled to the sixth input means; first coupling means for selectively engaging and disengaging one of the paths between the prime mover and the fifth input means, and second coupling means for selectively engaging and disengaging another of the paths between the prime mover and the sixth input means. The control means disengages one of the first and second coupling means in one of the paths when the other of the coupling means is engaged in the other of the paths.

  13. Time-Reversed Information Transmission

    NASA Astrophysics Data System (ADS)

    Gatlin, Lila L.

    1980-01-01

    Tolman's paradox forbidding time-reversed information transmission is nonexistent and rests only on our ingrained thought processes involving hidden, unnecessary assumptions. When the assumption of a passive channel is removed, the paradox cannot be derived and information can flow intermittently or nondeterministically from the future over a simple computer with at least one independent decision-making component.

  14. Immunology of naturally transmissible tumours

    E-print Network

    Siddle, Hannah V.; Kaufman, Jim

    2014-09-04

    Tasmanian devils. CTVT tumours are generally not fatal as a tumour specific host immune response controls or clears the tumours after transmission and a period of growth. In contrast, the growth of DFTD tumours is not controlled by the devil immune system...

  15. Cultural Transmission (or Social Learning)

    E-print Network

    Brown, Christopher A.

    's behavior We can define 4 types: Local enhancement Social facilitation Copying Imitation #12;2 Local locations Mating aggregations Social Facilitation Observer is drawn to an area by the presence alone1 Cultural Transmission (or Social Learning) An Example in Japanese Macaques One macaque (Imo

  16. Progressive transmission and compression images

    NASA Technical Reports Server (NTRS)

    Kiely, A. B.

    1996-01-01

    We describe an image data compression strategy featuring progressive transmission. The method exploits subband coding and arithmetic coding for compression. We analyze the Laplacian probability density, which closely approximates the statistics of individual subbands, to determine a strategy for ordering the compressed subband data in a way that improves rate-distortion performance. Results are presented for a test image.

  17. Immunology of naturally transmissible tumours

    PubMed Central

    Siddle, Hannah V; Kaufman, Jim

    2015-01-01

    Naturally transmissible tumours can emerge when a tumour cell gains the ability to pass as an infectious allograft between individuals. The ability of these tumours to colonize a new host and to cross histocompatibility barriers contradicts our understanding of the vertebrate immune response to allografts. Two naturally occurring contagious cancers are currently active in the animal kingdom, canine transmissible venereal tumour (CTVT), which spreads among dogs, and devil facial tumour disease (DFTD), among Tasmanian devils. CTVT are generally not fatal as a tumour-specific host immune response controls or clears the tumours after transmission and a period of growth. In contrast, the growth of DFTD tumours is not controlled by the Tasmanian devil's immune system and the disease causes close to 100% mortality, severely impacting the devil population. To avoid the immune response of the host both DFTD and CTVT use a variety of immune escape strategies that have similarities to many single organism tumours, including MHC loss and the expression of immunosuppressive cytokines. However, both tumours appear to have a complex interaction with the immune system of their respective host, which has evolved over the relatively long life of these tumours. The Tasmanian devil is struggling to survive with the burden of this disease and it is only with an understanding of how DFTD passes between individuals that a vaccine might be developed. Further, an understanding of how these tumours achieve natural transmissibility should provide insights into general mechanisms of immune escape that emerge during tumour evolution. PMID:25187312

  18. Immunology of naturally transmissible tumours.

    PubMed

    Siddle, Hannah V; Kaufman, Jim

    2015-01-01

    Naturally transmissible tumours can emerge when a tumour cell gains the ability to pass as an infectious allograft between individuals. The ability of these tumours to colonize a new host and to cross histocompatibility barriers contradicts our understanding of the vertebrate immune response to allografts. Two naturally occurring contagious cancers are currently active in the animal kingdom, canine transmissible venereal tumour (CTVT), which spreads among dogs, and devil facial tumour disease (DFTD), among Tasmanian devils. CTVT are generally not fatal as a tumour-specific host immune response controls or clears the tumours after transmission and a period of growth. In contrast, the growth of DFTD tumours is not controlled by the Tasmanian devil's immune system and the disease causes close to 100% mortality, severely impacting the devil population. To avoid the immune response of the host both DFTD and CTVT use a variety of immune escape strategies that have similarities to many single organism tumours, including MHC loss and the expression of immunosuppressive cytokines. However, both tumours appear to have a complex interaction with the immune system of their respective host, which has evolved over the relatively long life of these tumours. The Tasmanian devil is struggling to survive with the burden of this disease and it is only with an understanding of how DFTD passes between individuals that a vaccine might be developed. Further, an understanding of how these tumours achieve natural transmissibility should provide insights into general mechanisms of immune escape that emerge during tumour evolution. PMID:25187312

  19. Power superconducting power transmission cable

    DOEpatents

    Ashworth, Stephen P.

    2003-06-10

    The present invention is for a compact superconducting power transmission cable operating at distribution level voltages. The superconducting cable is a conductor with a number of tapes assembled into a subconductor. These conductors are then mounted co-planarly in an elongated dielectric to produce a 3-phase cable. The arrangement increases the magnetic field parallel to the tapes thereby reducing ac losses.

  20. Power superconducting power transmission cable

    DOEpatents

    Ashworth, Stephen P. (Cambridge, GB)

    2003-01-01

    The present invention is for a compact superconducting power transmission cable operating at distribution level voltages. The superconducting cable is a conductor with a number of tapes assembled into a subconductor. These conductors are then mounted co-planarly in an elongated dielectric to produce a 3-phase cable. The arrangement increases the magnetic field parallel to the tapes thereby reducing ac losses.