Science.gov

Sample records for 4232-dcc hints briefs

  1. Hints.

    PubMed

    Abu-Mostafa, Y S

    1995-07-01

    The systematic use of hints in the learning-from-examples paradigm is the subject of this review. Hints are the properties of the target function that are known to use independently of the training examples. The use of hints is tantamount to combining rules and data in learning, and is compatible with different learning models, optimization techniques, and regularization techniques. The hints are represented to the learning process by virtual examples, and the training examples of the target function are treated on equal footing with the rest of the hints. A balance is achieved between the information provided by the different hints through the choice of objective functions and learning schedules. The Adaptive Minimization algorithm achieves this balance by relating the performance on each hint to the overall performance. The application of hints in forecasting the very noisy foreign-exchange markets is illustrated. On the theoretical side, the information value of hints is contrasted to the complexity value and related to the VC dimension. PMID:7584883

  2. Errors in Crystal structure of HINT from Helicobacter pylori

    PubMed Central

    Maize, Kimberly M.

    2016-01-01

    Inaccuracies in the article, Crystal structure of HINT from Helicobacter pylori by Tarique et al. [(2016) Acta Cryst. F72, 42–48] are presented, and a brief history of HINT nomenclature is discussed. PMID:27050269

  3. HINTS Puerto Rico: Final Report

    Cancer.gov

    This final report describes HINTS implementation in Puerto Rico. The report addresses sampling; staffing, training and management of data collection; calling protocol; findings from the CATI Operations, and sample weights.

  4. Hint, hint: theory of mind performance in schizotypal individuals.

    PubMed

    Pflum, Madeline Johnson; Gooding, Diane Carol; White, Hannah Jean

    2013-05-01

    Studying Theory of Mind (ToM) performance in nonclinical populations may assist our understanding of underlying cognitive processes and contributing factors. ToM was assessed in three groups of psychometrically identified schizotypes, namely, individuals elevated on scales assessing positive schizotypy, those elevated on scales assessing negative schizotypy, and those elevated on both positive and negative schizotypy scales, using two hinting tasks. Individuals characterized by positive schizotypy showed poorer ToM performance compared with controls. The results suggest that individuals with elevated positive schizotypy scores experience more difficulty inferring the meaning of others' mental states (i.e., intentions) via indirect speech, such as hints. The negative schizotypy group did not differ from the nonschizotypy group in ToM performance. These findings are considered in terms of cognitive processing styles and implications for possible intervention. They also provide support for the inclusion of multiple groups of schizotypal individuals when assessing social cognition. PMID:23588225

  5. Cosmological hints of modified gravity?

    NASA Astrophysics Data System (ADS)

    Di Valentino, Eleonora; Melchiorri, Alessandro; Silk, Joseph

    2016-01-01

    The recent measurements of cosmic microwave background (CMB) temperature and polarization anisotropies made by the Planck satellite have provided impressive confirmation of the Λ CDM cosmological model. However interesting hints of slight deviations from Λ CDM have been found, including a 95% C.L. preference for a "modified gravity" (MG) structure formation scenario. In this paper we confirm the preference for a modified gravity scenario from Planck 2015 data, find that modified gravity solves the so-called Alens anomaly in the CMB angular spectrum, and constrains the amplitude of matter density fluctuations to σ8=0.81 5-0.048+0.032 , in better agreement with weak lensing constraints. Moreover, we find a lower value for the reionization optical depth of τ =0.059 ±0.020 (to be compared with the value of τ =0.079 ±0.017 obtained in the standard scenario), more consistent with recent optical and UV data. We check the stability of this result by considering possible degeneracies with other parameters, including the neutrino effective number, the running of the spectral index and the amount of primordial helium. The indication for modified gravity is still present at about 95% C.L., and could become more significant if lower values of τ were to be further confirmed by future cosmological and astrophysical data. When the CMB lensing likelihood is included in the analysis the statistical significance for MG simply vanishes, indicating also the possibility of a systematic effect for this MG signal.

  6. Enhancing the Automatic Generation of Hints with Expert Seeding

    ERIC Educational Resources Information Center

    Stamper, John; Barnes, Tiffany; Croy, Marvin

    2011-01-01

    The Hint Factory is an implementation of our novel method to automatically generate hints using past student data for a logic tutor. One disadvantage of the Hint Factory is the time needed to gather enough data on new problems in order to provide hints. In this paper we describe the use of expert sample solutions to "seed" the hint generation…

  7. Health Hints: Use Caution with Pain Relievers

    MedlinePlus

    ... Resources for You Health Hints: Use Caution with Pain Relievers. Share Tweet Linkedin Pin it More sharing options ... Pin it Email Print PDF version (447KB) (NAPS) -- Pain relievers, when used correctly, are safe and effective. Millions ...

  8. Crystal structure of HINT from Helicobacter pylori.

    PubMed

    Tarique, K F; Devi, S; Abdul Rehman, S A; Gourinath, S

    2016-01-01

    Proteins belonging to the histidine triad (HIT) superfamily bind nucleotides and use the histidine triad motif to carry out dinucleotidyl hydrolase, nucleotidyltransferase and phosphoramidite hydrolase activities. Five different branches of this superfamily are known to exist. Defects in these proteins in humans are linked to many diseases such as ataxia, diseases of RNA metabolism and cell-cycle regulation, and various types of cancer. The histidine triad nucleotide protein (HINT) is nearly identical to proteins that have been classified as protein kinase C-interacting proteins (PKCIs), which also have the ability to bind and inhibit protein kinase C. The structure of HINT, which exists as a homodimer, is highly conserved from humans to bacteria and shares homology with the product of fragile histidine triad protein (FHit), a tumour suppressor gene of this superfamily. Here, the structure of HINT from Helicobacter pylori (HpHINT) in complex with AMP is reported at a resolution of 3 Å. The final model has R and Rfree values of 26 and 28%, respectively, with good electron density. Structural comparison with previously reported homologues and phylogenetic analysis shows H. pylori HINT to be the smallest among them, and suggests that it branched out separately during the course of evolution. Overall, this structure has contributed to a better understanding of this protein across the animal kingdom. PMID:26750483

  9. Astrophysical hints of axion-like particles

    NASA Astrophysics Data System (ADS)

    Roncadelli, M.; Galanti, G.; Tavecchio, F.; Bonnoli, G.

    2015-01-01

    After reviewing three astrophysical hints of the existence of axion-like particles (ALPs), we describe in more detail a new similar hint involving flat spectrum radio quasars (FSRQs). Detection of FSRQs above about 20GeV pose a challenge to very-high-energy (VHE) astrophysics, because at those energies the ultraviolet emission from their broad line region should prevent photons produced by the central engine to leave the source. Although a few astrophysical explanations have been put forward, they are totally ad hoc. We show that a natural explanation instead arises within the conventional models of FSRQs provided that photon-ALP oscillations occur inside the source. Our analysis takes the FSRQ PKR 1222+206 as an example, and it looks tantalizing that basically the same choice of the free model parameters adopted in this case is consistent with those that provide the other three hints of the existence of ALPs.

  10. Study Surfaces Helpful Hints for Teachers.

    ERIC Educational Resources Information Center

    Educational R&D Report, 1979

    1979-01-01

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT Far West Laboratory researchers involved in the Beginning Teacher Evaluation Study contend that increasing Academic Learning Time promotes basic skills achievement among elementary school children. During the course of the six-year study, researchers identified numerous "helpful hints" for producing…

  11. Data-Driven Hint Generation from Peer Debugging Solutions

    ERIC Educational Resources Information Center

    Liu, Zhongxiu

    2015-01-01

    Data-driven methods have been a successful approach to generating hints for programming problems. However, the majority of previous studies are focused on procedural hints that aim at moving students to the next closest state to the solution. In this paper, I propose a data-driven method to generate remedy hints for BOTS, a game that teaches…

  12. Quantum speed problem: Theoretical hints for control

    NASA Astrophysics Data System (ADS)

    Lisboa, Alexandre Coutinho; Piqueira, José Roberto Castilho

    2016-06-01

    The transition time between states plays an important role in designing quantum devices as they are very sensitive to environmental influences. Decoherence phenomenon is responsible for possible destructions of the entanglement that is a fundamental requirement to implement quantum information processing systems. If the time between states is minimized, the decoherence effects can be reduced, thus, it is advantageous to the designer to develop expressions for time performance measures. Quantum speed limit (QSL) problem has been studied from the theoretical point of view, providing general results. Considering the implementation of quantum control systems, as the decoherence phenomenon is unavoidable, it is important to apply these general results to particular cases, developing expressions and performance measures, to assist control engineering designers. Here, a minimum time performance measure is defined for quantum control problems, for time-independent or time-dependent Hamiltonians, and applied to some practical examples, providing hints that may be useful for researchers pursuing optimization strategies for quantum control systems.

  13. Structured hints : extracting and abstracting domain expertise.

    SciTech Connect

    Hereld, M.; Stevens, R.; Sterling, T.; Gao, G. R.; Mathematics and Computer Science; California Inst. of Tech.; Louisiana State Univ.; Univ. of Delaware

    2009-03-16

    We propose a new framework for providing information to help optimize domain-specific application codes. Its design addresses problems that derive from the widening gap between the domain problem statement by domain experts and the architectural details of new and future high-end computing systems. The design is particularly well suited to program execution models that incorporate dynamic adaptive methodologies for live tuning of program performance and resource utilization. This new framework, which we call 'structured hints', couples a vocabulary of annotations to a suite of performance metrics. The immediate target is development of a process by which a domain expert describes characteristics of objects and methods in the application code that would not be readily apparent to the compiler; the domain expert provides further information about what quantities might provide the best indications of desirable effect; and the interactive preprocessor identifies potential opportunities for the domain expert to evaluate. Our development of these ideas is progressing in stages from case study, through manual implementation, to automatic or semi-automatic implementation. In this paper we discuss results from our case study, an examination of a large simulation of a neural network modeled after the neocortex.

  14. Altered specificity of Hint-W123Q supports a role for Hint inhibition by ASW in avian sex determination.

    PubMed

    Parks, Kristen P; Seidle, Heather; Wright, Nathan; Sperry, Jeffrey B; Bieganowski, Pawel; Howitz, Konrad; Wright, Dennis L; Brenner, Charles

    2004-12-15

    Hint is a universally conserved, dimeric AMP-lysine hydrolase encoded on the avian Z chromosome. Tandemly repeated on the female-specific W chromosome, Asw encodes a potentially sex-determining, dominant-negative Hint dimerization partner whose substrate-interacting residues were specifically altered in evolution. To test the hypothesis that Gln127 of Asw is responsible for depression and/or alteration of Hint enzyme activity, a corresponding mutant was created in the chicken Hint homodimer, and a novel substrate was developed that links reversal of AMP-lysine modification to aminomethylcoumarin release. Strikingly, the Hint-W123Q substitution reduced k(cat)/K(m) for AMP-lysine hydrolysis 17-fold, while it increased specificity for AMP-para-nitroaniline hydrolysis by 160-fold. The resulting 2,700-fold switch in enzyme specificity suggests that Gln127 could be the dominant component of Asw dominant negativity in avian feminization. PMID:15507519

  15. Flexible synthesis of video frames based on motion hints.

    PubMed

    Naman, Aous Thabit; Taubman, David

    2014-09-01

    In this paper, we propose the use of "motion hints" to produce interframe predictions. A motion hint is a loose and global description of motion that can be communicated using metadata; it describes a continuous and invertible motion model over multiple frames, spatially overlapping other motion hints. A motion hint provides a reasonably accurate description of motion but only a loose description of where it is applicable; it is the task of the client to identify the exact locations where this motion model is applicable. The focus of this paper is a probabilistic multiscale approach to identifying these locations of applicability; the method is robust to noise, quantization, and contrast changes. The proposed approach employs the Laplacian pyramid; it generates motion hint probabilities from observations at each scale of the pyramid. These probabilities are then combined across the scales of the pyramid starting from the coarsest scale. The computational cost of the approach is reasonable, and only the neighborhood of a pixel is employed to determine a motion hint probability, which makes parallel implementation feasible. This paper also elaborates on how motion hint probabilities are exploited in generating interframe predictions. The scheme of this paper is applicable to closed-loop prediction, but it is more useful in open-loop prediction scenarios, such as using prediction in conjunction with remote browsing of surveillance footage, communicated by a JPEG2000 Interactive Protocol (JPIP) server. We show that the interframe predictions obtained using the proposed approach are good both visually and in terms of PSNR. PMID:24968173

  16. Study Hints At HPV Vaccine's Cancer Prevention Promise

    MedlinePlus

    ... gov/news/fullstory_159696.html Study Hints at HPV Vaccine's Cancer Prevention Promise Fewer vaccinated young women ... July 4, 2016 (HealthDay News) -- The human papillomavirus (HPV) vaccine appears to prevent abnormalities that can lead ...

  17. Study Hints At HPV Vaccine's Cancer Prevention Promise

    MedlinePlus

    ... news/fullstory_159696.html Study Hints at HPV Vaccine's Cancer Prevention Promise Fewer vaccinated young women had ... 4, 2016 (HealthDay News) -- The human papillomavirus (HPV) vaccine appears to prevent abnormalities that can lead to ...

  18. Report Hints Zika Can Spread Through Oral Sex

    MedlinePlus

    ... html Report Hints Zika Can Spread Through Oral Sex French finding adds to growing evidence that sexual ... the Zika virus can be transmitted through oral sex. Zika is typically spread through the bite of ...

  19. 110. Photocopy of plate opposite page 19 in Owen, Hints. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    110. Photocopy of plate opposite page 19 in Owen, Hints. CAMPANILE, SMITHSONIAN INSTITUTION, FROM THE NORTH-EAST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  20. 108. Photocopy of frontispiece in Owen, Hints. MAIN ENTRANCE, NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    108. Photocopy of frontispiece in Owen, Hints. MAIN ENTRANCE, NORTH FRONT, SMITHSONIAN INSTITUTION - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  1. 107. Photocopy of plate opposite page 104 in Owen, Hints. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    107. Photocopy of plate opposite page 104 in Owen, Hints. SMITHSONIAN INSTITUTION, FROM THE NORTH-EAST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  2. 112. Photocopy of plate opposite page 43 in Owen, Hints. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    112. Photocopy of plate opposite page 43 in Owen, Hints. CENTRAL SOUTHERN TOWER, SMITHSONIAN INSTITUTION; FROM THE SOUTH-WEST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  3. 113. Photocopy of illustration on page 109 in Owen, Hints. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    113. Photocopy of illustration on page 109 in Owen, Hints. SOUTHERN GATEWAY, SMITHSONIAN INSTITUTION - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  4. 109. Photocopy of plate opposite page 75 in Owen, Hints. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    109. Photocopy of plate opposite page 75 in Owen, Hints. WEST WING, SMITHSONIAN INSTITUTION: FROM THE NORTH-EAST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  5. 106. Photocopy of plate opposite pge 99 in Owen, Hints. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    106. Photocopy of plate opposite pge 99 in Owen, Hints. GOTHIC DESIGN FOR SMITHSONIAN INSTITUTION - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  6. 111. Photocopy of plate opposite page 108 in Owen, Hints. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    111. Photocopy of plate opposite page 108 in Owen, Hints. SMITHSONIAN INSTITUTION FROM THE SOUTH WEST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  7. Report Hints Zika Can Spread Through Oral Sex

    MedlinePlus

    ... medlineplus.gov/news/fullstory_159189.html Report Hints Zika Can Spread Through Oral Sex French finding adds ... A new report from France suggests that the Zika virus can be transmitted through oral sex. Zika ...

  8. Eating Hints: Before, During, and After Cancer Treatment

    MedlinePlus

    ... Therapies Fact Sheets NCI Dictionaries NCI Dictionary of Cancer Terms NCI Drug Dictionary NCI Dictionary of Genetics Terms Blogs and Newsletters Health Communications Publications Reports Eating Hints: Before, During, and After ...

  9. Hints from Run 1 and prospects from Run 2 at ATLAS

    NASA Astrophysics Data System (ADS)

    Bernius, Catrin

    2016-06-01

    The Large Hadron Collider at CERN has allowed the ATLAS experiment to collect a large amount of proton-proton collision data at 7 TeV and 8 TeV centre-of-mass energies throughout Run 1. This dataset was used to discover a Higgs boson with Standard Model-like properties at a mass of about 125 GeV. Furthermore, an impressive number of searches for deviations from the Standard Model expectations have been carried out. To date, no evidence for new physics beyond the SM has been found. However, a few hints in form of 2-3 σ deviations have been observed. After an 18-month shutdown, in which the ATLAS detector has undergone various upgrades, the LHC has again started to deliver collision data at an increased centre-of-mass energy of 13 TeV, providing a much improved sensitivity for various searches, in particular for high mass particles. Some representative hints at the LHC Run 1 are presented, a brief overview of ATLAS upgrades and prospects for SUSY searches with early Run 2 data are given.

  10. An analytical model of the HINT performance metric

    SciTech Connect

    Snell, Q.O.; Gustafson, J.L.

    1996-10-01

    The HINT benchmark was developed to provide a broad-spectrum metric for computers and to measure performance over the full range of memory sizes and time scales. We have extended our understanding of why HINT performance curves look the way they do and can now predict the curves using an analytical model based on simple hardware specifications as input parameters. Conversely, by fitting the experimental curves with the analytical model, hardware specifications such as memory performance can be inferred to provide insight into the nature of a given computer system.

  11. Helpful Hints for School Emergency Management: Emergency "Go-Kits"

    ERIC Educational Resources Information Center

    Hill, Tara

    2006-01-01

    "Helpful Hints" offers a quick overview of school emergency preparedness topics that are frequently the subject of inquiries. The Office of Safe and Drug-Free Schools (OSDFS) encourages schools to consider emergency management in the context of its four phases: mitigation and prevention, preparedness, response, and recovery. The preparedness phase…

  12. Hints on the use of the PCMDI Visualization and Computation System (VCS)

    SciTech Connect

    Williams, Dean N.; Drach, R. S.; Mobley, R. L.; Phillips, T. J.

    1995-04-01

    This report documents the Hints interactive displays that assist a user of the PCMDI Visualization and Computation System (VCS). These Hints describe the purpose of the VCS panels and provide basic instructions on their use.

  13. Issue Brief #2: Metrics for Improving Cost Accountability (Hint: Not More Detailed Cost Accounting...)

    ERIC Educational Resources Information Center

    Delta Project on Postsecondary Education Costs, Productivity and Accountability, 2009

    2009-01-01

    Most fiscal reporting focuses on revenues (whether or not they go to core purposes), tuition and fees, and financial aid. "How" the money is spent is something that remains shrouded in too much mystery. Several national efforts to address this problem have largely come to naught--probably because those common methodologies are simultaneously not…

  14. A two-Higgs-doublet model facing experimental hints

    NASA Astrophysics Data System (ADS)

    Crivellin, Andreas; Heeck, Julian; Stoffer, Peter

    2016-04-01

    Physics beyond the Standard Model has so far eluded our experimental probes. Nevertheless, a number of interesting anomalies have accumulated that can be taken as hints towards new physics: BaBar, Belle, and LHCb have found deviations of approximately 3:8σ in B → Dτν and B → D*τν; the anomalous magnetic moment of the muon differs by about 3σ from the theoretic prediction; the branching ratio for τ → μνν is about 2σ above the Standard Model expectation; and CMS and ATLAS found hints for a non-zero decay rate of h → μτ at 2.6σ. Here we consider these processes within a lepton-specific two-Higgs doublet model with additional non-standard Yukawa couplings and show how (and which of) these excesses can be accommodated.

  15. Hint1 knockout results in a compromised activation of protein kinase C gamma in the brain.

    PubMed

    Zhang, Fan; Fang, Zhenfei; Wang, Jia Bei

    2015-10-01

    Previous studies have implicated a role of the histidine triad nucleotide-binding protein 1 (Hint1) in the pathogenesis of schizophrenia. Protein kinase C gamma (PKCγ) could be potentially involved in the Hint1-implicated pathogenesis since PKCγ was identified as a Hint1 interacting protein. Recently, a debate was brought forward from the understanding how Hint1 affects the expression and activity of PKCγ in the brain. In the present study, we use Hint1 knockout mice and biochemical analysis to define the effect of Hint1 on protein PKCγ. Our data reveal that Hint1-deficiency in mouse brains led to increased protein levels of PKCγ in the cortex and hippocampus, the striatum and thalamus and amygdala. Without stimulation, PKCγ protein in Hint1-deficient brain displayed a basal activity that was reflected by control-leveled phosphorylations of PKCγ T514 and T674 at its kinase domain. Upon psycho-stimulation, both sites of PKCγ T514 and T674 were activated in these brain structures via phosphorylation; however, the phosphorylation level at the site of PKCγ T674 apparently attenuated in Hint1-deficient mice compared to wild-type control. Thus, we conclude that Hint1 deficiency leads to an increased protein level of PKCγ in the brain and a compromised activation response of PKCγ upon stimulation. These findings suggest an inhibitory role of Hint1 on the protein PKCγ in the brain and an impaired PKCγ-mediated phosphorylation signal in Hint1-deficient neuron. PMID:26133792

  16. Industry briefs

    SciTech Connect

    1990-11-01

    Recent nuclear industry briefs are presented. These briefs include: President Bush signs Radiation Victim Compensation Act; Japan Nuclear Fuel Completes construction of Rokkasho Enrichment Plant; Japanese vapor laser achieves 5% enrichment; US to cooperate with Hungary and Czechoslovakia on nuclear power; Soviet Union may reopen nuclear station in Armenia; despite earthquake concerns; and Japan`s Kashiwazak; Kaviwa - 2 begins commercial operation.

  17. Legacy limits and hints of New Physics at the Tevatron

    SciTech Connect

    Duperrin, Arnaud; /Marseille, CPPM

    2011-12-01

    This paper reviews results of beyond-the-standard model searches at the Tevatron presented in a plenary talk at the Europhysics Conference on High Energy Physics (EPS-HEP) in Grenoble. Here I present a selection of results from the CDF and D0 experiments that were shown at the conference during the parallel sessions. Much more is available and can be found at the experiment's web pages. This proceeding essentially focuses on searches in the dilepton, diboson, and t{bar t} final states. Throughout the paper, hints of new physics observed at the Tevatron are also briefly discussed.

  18. Understanding Attention to Adaptive Hints in Educational Games: An Eye-Tracking Study

    ERIC Educational Resources Information Center

    Conati, Cristina; Jaques, Natasha; Muir, Mary

    2013-01-01

    This paper presents a user study that investigates the factors affecting student attention to user-adaptive hints during interaction with an educational computer game. The study focuses on Prime Climb, an educational game designed to provide individualized support for learning number factorization skills in the form of textual hints based on a…

  19. Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1.

    PubMed

    Shah, Rachit; Strom, Alexander; Zhou, Andrew; Maize, Kimberly M; Finzel, Barry C; Wagner, Carston R

    2016-08-11

    Hint1 has recently emerged to be an important target of interest due to its involvement in the regulation of a broad range of CNS functions including opioid signaling, tolerance, neuropathic pain, and nicotine dependence. A series of inhibitors were rationally designed, synthesized, and tested for their inhibitory activity against hHint1 using isothermal titration calorimetry (ITC). The studies resulted in the development of the first small-molecule inhibitors of hHint1 with submicromolar binding affinities. A combination of thermodynamic and high-resolution X-ray crystallographic studies provides an insight into the biomolecular recognition of ligands by hHint1. These novel inhibitors have potential utility as molecular probes to better understand the role and function of hHint1 in the CNS. PMID:27563403

  20. Hints for Enhanced b -> sg From Charm and Kaon Counting

    SciTech Connect

    Rathsman, Johan

    2003-05-09

    Previously, motivation for enhanced b {yields} sg from new flavor physics has centered on discrepancies between theory and experiment. Here two experimental hints are considered: (1) updated measurements of the charm multiplicity and {Beta}({bar B} {yields} X{sub c{bar c}s}) at the {Upsilon}(4S) imply {Beta}(B {yields} X{sub no charm}) {approx} 12.4 {+-} 5.6%, (2) the {bar B} {yields} K{sup -}X and {bar B} {yields} K{sup +}/K{sup -}X branching fractions are in excess of conventional {bar B} {yields} X{sub c} {yields} KX yields by about 16.9 {+-} 5.6% and 18 {+-} 5.3%, respectively. JETSET 7.4 was used to estimate kaon yields from s{bar s} popping in {bar B} {yields} X{sub c{bar u}d} decays. JETSET 7.4 Monte Carlos for {Beta}({bar B} {yields} X{sub sg}) {approx} 15% imply that the additional kaon production would lead to 1{sigma} agreement with observed charged and neutral kaon yields. The K{sub s} momentum spectrum would be consistent with recent CLEO bounds in the end point region. Search strategies for enhanced b {yields} sg are discussed in light of large theoretical uncertainty in the standard model fast kaon background from b {yields} s penguin operators.

  1. Acute behavioral effects of nicotine in male and female HINT1 knockout mice.

    PubMed

    Jackson, K J; Wang, J B; Barbier, E; Chen, X; Damaj, M I

    2012-11-01

    Human genetic association and brain expression studies, and mouse behavioral and molecular studies implicate a role for the histidine triad nucleotide-binding protein 1 (HINT1) in schizophrenia, bipolar disorder, depression and anxiety. The high comorbidity between smoking and psychiatric disorders, schizophrenia in particular, is well established. Associations with schizophrenia and HINT1 are also sex specific, with effects more predominant in males; however, it is unknown if sex differences associated with the gene extend to other phenotypes. Thus, in this study, using a battery of behavioral tests, we elucidated the role of HINT1 in acute nicotine-mediated behaviors using male and female HINT1 wild-type (+/+) and knockout (-/-) mice. The results show that male HINT1 -/- mice were less sensitive to acute nicotine-induced antinociception in the tail-flick, but not hot-plate test. At low nicotine doses, male and female HINT1 -/- mice were less sensitive to nicotine-induced hypomotility, although the effect was more pronounced in females. Baseline differences in locomotor activity observed in male HINT1 +/+ and -/- mice were absent in females. Nicotine did not produce an anxiolytic effect in male HINT1 -/- mice, but rather an anxiogenic response. Diazepam also failed to induce an anxiolytic response in these mice, suggesting a general anxiety phenotype not specific to nicotine. Differences in anxiety-like behavior were not observed in female mice. These results further support a role for HINT1 in nicotine-mediated behaviors and suggest that alterations in the gene may have differential effects on phenotype in males and females. PMID:22827509

  2. Hints of Period Change for OGLE-TR-113b

    NASA Astrophysics Data System (ADS)

    Adams, Elisabeth R.; Lopez-Morales, M.; Elliot, J. L.; Seager, S.; Osip, D. J.

    2010-10-01

    We present six new transits of the hot Jupiter OGLE-TR-113b observed with MagIC on the Magellan Telescopes between January 2007 and May 2009. We update the system parameters and revise the planetary radius, where the error is dominated by stellar radius uncertainties. The new transit midtimes reveal no transit timing variations from a constant ephemeris over two years, which places an upper limit of 1-2 Earth masses on any perturber in a 1:2 or 2:1 mean-motion resonance with OGLE-TR-113b. Combining the new transit epochs with five epochs published between 2002 and 2006, we find hints that the orbital period of the planet may not be constant, with the best fit indicating the period is decreasing by 60±15 milliseconds per year. If real, this change in period could result from either a long-period (more than 8 years) timing variation due to an external perturber, or more intriguingly from the orbital decay of the planet. The detection of a changing period is still tentative and must be checked with additional observations. If a period decay is confirmed, OGLE-TR-113b will be the first planet observed to be falling onto its star. This would enable direct tests of tidal stability and dynamical models of close-in planets and place observational constraints on the value of stellar tidal energy dissipation factors. This work was supported in part by NASA Origins grant NNX07AN63G and Hubble Fellowship grant HF-01210.01-A/HF-51233.01 awarded by the STScI, which is operated by the AURA, Inc. for NASA, under contract NAS5-26555.

  3. HINT1 is involved in the behavioral abnormalities induced by social isolation rearing.

    PubMed

    Dang, Yong-hui; Liu, Peng; Ma, Rui; Chu, Zheng; Liu, You-ping; Wang, Jia-bei; Ma, Xian-cang; Gao, Cheng-ge

    2015-10-21

    Social isolation (SI) rearing has been demonstrated to induce behavioral abnormalities like anxiety, impulsivity, aggression, and learning and memory deficits which are relevant to core symptoms in patients with some certain neuropsychiatric disorders. But the underlying pathophysiological mechanisms remain unclear. Recent studies have revealed HINT1 has close relation with diverse neuropsychiatric diseases. In this present study, the SI rearing mice exhibited depression-like and aggressive behavior. Besides, HINT1 protein levels decreased in PFC but increased in HIP. Based on the data obtained, we concluded that HINT1 is involved in the behavioral abnormalities induced by social isolation and exerts distinct roles in different encephalic regions. PMID:26300541

  4. HinT proteins and their putative interaction partners in Mollicutes and Chlamydiaceae

    PubMed Central

    Hopfe, Miriam; Hegemann, Johannes H; Henrich, Birgit

    2005-01-01

    Background HinT proteins are found in prokaryotes and eukaryotes and belong to the superfamily of HIT proteins, which are characterized by an histidine-triad sequence motif. While the eukaryotic variants hydrolyze AMP derivates and modulate transcription, the function of prokaryotic HinT proteins is less clearly defined. In Mycoplasma hominis, HinT is concomitantly expressed with the proteins P60 and P80, two domains of a surface exposed membrane complex, and in addition interacts with the P80 moiety. Results An cluster of hitABL genes, similar to that of M. hominis was found in M. pulmonis, M. mycoides subspecies mycoides SC, M. mobile and Mesoplasma florum. RT-PCR analyses provided evidence that the P80, P60 and HinT homologues of M. pulmonis were polycistronically organized, suggesting a genetic and physical interaction between the proteins encoded by these genes in these species. While the hit loci of M. pneumoniae and M. genitalium encoded, in addition to HinT, a protein with several transmembrane segments, the hit locus of Ureaplasma parvum encoded a pore-forming protein, UU270, a P60 homologue, UU271, HinT, UU272, and a membrane protein of unknown function, UU273. Although a full-length mRNA spanning the four genes was not detected, amplification of all intergenic regions from the center of UU270 to the end of UU273 by RT-PCR may be indicative of a common, but unstable mRNA. In Chlamydiaceae the hit gene is flanked upstream by a gene predicted to encode a metal dependent hydrolase and downstream by a gene putatively encoding a protein with ARM-repeats, which are known to be involved in protein-protein interactions. In RT-PCR analyses of C. pneumoniae, regions comprising only two genes, Cp265/Cp266 and Cp266/Cp267 were able to be amplified. In contrast to this in vivo interaction analysis using the yeast two-hybrid system and in vitro immune co-precipitation revealed an interaction between Cp267, which contains the ARM repeats, Cp265, the predicted hydrolase

  5. Inflammatory Stress and Idiosyncratic Hepatotoxicity: Hints from Animal Models

    PubMed Central

    Deng, Xiaomin; Luyendyk, James P.; Ganey, Patricia E.

    2009-01-01

    Adverse drug reactions (ADRs) present a serious human health problem. They are major contributors to hospitalization and mortality throughout the world (Lazarou et al., 1998; Pirmohamed et al., 2004). A small fraction (less than 5%) of ADRs can be classified as “idiosyncratic.” Idiosyncratic ADRs (IADRs) are caused by drugs with diverse pharmacological effects and occur at various times during drug therapy. Although IADRs affect a number of organs, liver toxicity occurs frequently and is the primary focus of this review. Because of the inconsistency of clinical data and the lack of experimental animal models, how IADRs arise is largely undefined. Generation of toxic drug metabolites and induction of specific immunity are frequently cited as causes of IADRs, but definitive evidence supporting either mechanism is lacking for most drugs. Among the more recent hypotheses for causation of IADRs is that inflammatory stress induced by exogenous or endogenous inflammagens is a susceptibility factor. In this review, we give a brief overview of idiosyncratic hepatotoxicity and the inflammatory response induced by bacterial lipopolysaccharide. We discuss the inflammatory stress hypothesis and use as examples two drugs that have caused IADRs in human patients: ranitidine and diclofenac. The review focuses on experimental animal models that support the inflammatory stress hypothesis and on the mechanisms of hepatotoxic response in these models. The need for design of epidemiological studies and the potential for implementation of inflammation interaction studies in preclinical toxicity screening are also discussed briefly. PMID:19805476

  6. Inflammatory stress and idiosyncratic hepatotoxicity: hints from animal models.

    PubMed

    Deng, Xiaomin; Luyendyk, James P; Ganey, Patricia E; Roth, Robert A

    2009-09-01

    Adverse drug reactions (ADRs) present a serious human health problem. They are major contributors to hospitalization and mortality throughout the world (Lazarou et al., 1998; Pirmohamed et al., 2004). A small fraction (less than 5%) of ADRs can be classified as "idiosyncratic." Idiosyncratic ADRs (IADRs) are caused by drugs with diverse pharmacological effects and occur at various times during drug therapy. Although IADRs affect a number of organs, liver toxicity occurs frequently and is the primary focus of this review. Because of the inconsistency of clinical data and the lack of experimental animal models, how IADRs arise is largely undefined. Generation of toxic drug metabolites and induction of specific immunity are frequently cited as causes of IADRs, but definitive evidence supporting either mechanism is lacking for most drugs. Among the more recent hypotheses for causation of IADRs is that inflammatory stress induced by exogenous or endogenous inflammagens is a susceptibility factor. In this review, we give a brief overview of idiosyncratic hepatotoxicity and the inflammatory response induced by bacterial lipopolysaccharide. We discuss the inflammatory stress hypothesis and use as examples two drugs that have caused IADRs in human patients: ranitidine and diclofenac. The review focuses on experimental animal models that support the inflammatory stress hypothesis and on the mechanisms of hepatotoxic response in these models. The need for design of epidemiological studies and the potential for implementation of inflammation interaction studies in preclinical toxicity screening are also discussed briefly. PMID:19805476

  7. Hints at diapirism in Arabia Terra craters, Mars

    NASA Astrophysics Data System (ADS)

    Pozzobon, Riccardo; Pio Rossi, Angelo; Massironi, Matteo; Mazzarini, Francesco; Pondrelli, Monica; Marinangeli, Lucia; Unnithan, Vikram

    2014-05-01

    during bulge sequences deposition. One or - more likely - multiple layers of sulfates below the shallower levels of Arabia Terra surface need, in our opinion, to be hypothesized in order to explain all these contrasting observations. Indeed impact cratering on such an evaporate bearing layered target might have provided the ideal conditions of faulting, interconnectivity of evaporatic beds and lithostatic load release to allow diapirs ascent, In turn diapirism could have been responsible for central bulging as testified by outward dipping strata on stratified bulges, broad un-stratified bulges and folding (see Jackson and Vendeville, 1994 for typical salt tectonics). The depth of the fluid source calculated with a fractal method (Pozzobon et al., 2013) using the position of the small widespread mounds within Firsoff and Crommelin craters can give a hint of the average depth of the evaportic horizons (~4 km). As further developments we plan to test and quantify our model to take into account geological evidences, possible kinematics, rheology and stratigraphic constrains. References: Andrews-Hanna, J.C., and Lewis, K.W., 2011, Early Mars hydrology: 2. Hydrological evolution in the Noachian and Hesperian epochs: Journal of Geophysical Research, v. 116, p. E02007, doi: 10.1029/2010JE003709. Franchi, F., Rossi, A. P., Pondrelli, M., Cavalazzi, B. (2014) Geometry, stratigraphy and evidences for fluid expulsion within Crommelin crater deposits, Arabia Terra, Mars. Planet Space Sci., in press. DOI: 10.1016/j.pss.2013.12.013, Jackson M.P.A. & Vendeville B.C. (1994) - Regional extension as a geologic trigger for diapirism, GSA Bulletin, 106: 57-73, Pondrelli, M., Rossi, A. P., Ori, G.G., van Gasselt, S., Praeg, D., and Ceramicola, S., 2011, Mud volcanoes in the geologic record of Mars: The case of Firsoff crater: Earth and Planetary Science Letters, v. 304, p. 511-519, doi: 10.1016/j.epsl.2011.02.027., Pozzobon R. et al. (2013), AGU Fall Meeting, Abstract #1797270.

  8. Characterization of the Effect of the Mitochondrial Protein Hint2 on Intracellular Ca2+ dynamics

    PubMed Central

    Ndiaye, Dieynaba; Collado-Hilly, Mauricette; Martin, Juliette; Prigent, Sylvie; Dufour, Jean-François; Combettes, Laurent; Dupont, Geneviève

    2013-01-01

    Hint2, one of the five members of the superfamily of the histidine triad AMP-lysine hydrolase proteins, is expressed in mitochondria of various cell types. In human adrenocarcinoma cells, Hint2 modulates Ca2+ handling by mitochondria. As Hint2 is highly expressed in hepatocytes, we investigated if this protein affects Ca2+ dynamics in this cell type. We found that in hepatocytes isolated from Hint2−/− mice, the frequency of Ca2+ oscillations induced by 1 μM noradrenaline was 150% higher than in the wild-type. Using spectrophotometry, we analyzed the rates of Ca2+ pumping in suspensions of mitochondria prepared from hepatocytes of either wild-type or Hint2−/− mice; we found that Hint2 accelerates Ca2+ pumping into mitochondria. We then resorted to computational modeling to elucidate the possible molecular target of Hint2 that could explain both observations. On the basis of a detailed model for mitochondrial metabolism proposed in another study, we identified the respiratory chain as the most probable target of Hint2. We then used the model to predict that the absence of Hint2 leads to a premature opening of the mitochondrial permeability transition pore in response to repetitive additions of Ca2+ in suspensions of mitochondria. This prediction was then confirmed experimentally. PMID:24010670

  9. The Problem with Briefs, in Brief

    ERIC Educational Resources Information Center

    Conaway, Carrie L.

    2013-01-01

    Policy briefs written by academics--the kind typically published in "Education Finance and Policy"--should be a crucial source of information for policy makers. Yet too frequently these briefs fail to garner the consideration they deserve. Their authors are too focused on the potential objections of their fellow academics, who are…

  10. Adult Participation in Children's Word Searches: On the Use of Prompting, Hinting, and Supplying a Model

    ERIC Educational Resources Information Center

    Radford, Julie

    2010-01-01

    Although word searching in children is very common, very little is known about how adults support children in the turns following the child's search behaviours, an important topic because of the social, educational, and clinical implications. This study characterizes, in detail, teachers' use of prompting, hinting, and supplying a model. From a…

  11. Clinical-HINTS: integrated intelligent ICU patient monitoring and information management system.

    PubMed

    Kalogeropoulos, D; Carson, E R; Collinson, P O

    1997-01-01

    Clinical-HINTS (Health Intelligence System) is a horizontally integrated decision support system (DSS) designed to meet the requirements for intelligent real-time clinical information management in critical care medical environments and to lay the foundation for the development of the next generation of intelligent medical instrumentation. The system presented was developed to refine and complement the information yielded by clinical laboratory investigations, thereby benefiting the management of the intensive care unit (ICU) patient. More specifically, Clinical-HINTS was developed to provide computer-based assistance with the acquisition, organisation and display, storage and retrieval, communication and generation of real-time patient-specific clinical information in an ICU. Clinical-HINTS is an object-oriented system developed in C+2 to run under Microsoft Windows as an embryo intelligent agent. Current generic reasoning skills include perception and reactive cognition of patient status but exclude therapeutic action. The system monitors the patient by communicating with the available sources of data and uses generic reasoning skills to generate intelligent alarms, or HINTS, on various levels of interpretation of an observed dysfunction, even in the presence of complex disorders. The system's communication and information management capabilities are used to acquire physiological data, and to store them along with their interpretations and any interventions for the dynamic recognition of interrelated pathophysiological states or clinical events. PMID:10179800

  12. Interaction Networks: Generating High Level Hints Based on Network Community Clustering

    ERIC Educational Resources Information Center

    Eagle, Michael; Johnson, Matthew; Barnes, Tiffany

    2012-01-01

    We introduce a novel data structure, the Interaction Network, for representing interaction-data from open problem solving environment tutors. We show how using network community detecting techniques are used to identify sub-goals in problems in a logic tutor. We then use those community structures to generate high level hints between sub-goals.…

  13. Helpful Hints for School Emergency Management: Steps for Developing a School Emergency Management Plan

    ERIC Educational Resources Information Center

    US Department of Education, 2007

    2007-01-01

    "Helpful Hints" offers a quick overview of school emergency preparedness topics that are frequently the subject of inquiries. The U.S. Department of Education's Office of Safe and Drug-Free Schools strongly encourages schools and school districts to develop emergency management plans within the context of the four phases of emergency management:…

  14. Semantic Elaboration through Integration: Hints Both Facilitate and Inform the Process

    ERIC Educational Resources Information Center

    Bauer, Patricia J.; Varga, Nicole L.; King, Jessica E.; Nolen, Ayla M.; White, Elizabeth A.

    2015-01-01

    Semantic knowledge can be extended in a variety of ways, including self-generation of new facts through integration of separate yet related episodes. We sought to promote integration and self-generation by providing "hints" to help 6-year-olds (Experiment 1) and 4-year-olds (Experiment 2) see the relevance of separate episodes to one…

  15. Enhancement of Student Learning through the Use of a Hinting Computer E-Learning System and Comparison with Human Teachers

    ERIC Educational Resources Information Center

    Munoz-Merino, P. J.; Kloos, C. D.; Munoz-Organero, M.

    2011-01-01

    This paper reports the results of an experiment in a Computer Architecture Laboratory course classroom session, in which students were divided into two groups for interaction both with a hinting e-learning system and with human teachers generating hints. The results show that there were high learning gains for both groups, demonstrating the…

  16. Stoic Behavior Hypothesis in Hint Seeking and Development of Reversi Learning Environment as Work Bench for Investigation

    ERIC Educational Resources Information Center

    Miwa, Kazuhisa; Kojima, Kazuaki; Terai, Hitoshi

    2014-01-01

    Tutoring systems provide students with various types of on-demand and context-sensitive hints. Students are required to consciously adapt their help-seeking behavior, proactively seek help in some situations, and solve problems independently without supports in other situations. We define the latter behavior as stoic behavior in hint seeking. In…

  17. A Time Series Analysis of Cancer-Related Information Seeking: Hints From the Health Information National Trends Survey (HINTS) 2003-2014.

    PubMed

    Huerta, Timothy R; Walker, Daniel M; Johnson, Tyler; Ford, Eric W

    2016-09-01

    Recent technological changes, such as the growth of the Internet, have made cancer information widely available. However, it remains unknown whether changes in access have resulted in concomitant changes in information seeking behavior. Previous work explored the cancer information seeking behaviors of the general population using the 2003 Health Information National Trends Survey (HINTS). This article aims to reproduce, replicate, and extend that existing analysis using the original dataset and five additional iterations of HINTS (2007, 2011, 2012, 2013, 2014). This approach builds on the earlier work by quantifying the magnitude of change in information seeking behaviors. Bivariate comparison of the 2003 and 2014 data revealed very similar results; however, the multivariate model including all years of data indicated differences between the original and extended models: individuals age 65 and older were no longer less likely to seek cancer information than the 18-35 reference population, and Hispanics were also no longer less likely to be cancer information seekers. The results of our analysis indicate an overall shift in cancer information seeking behaviors and also illuminate the impact of increased Internet usage over the past decade, suggesting specific demographic groups that may benefit from cancer information seeking encouragement. PMID:27565190

  18. The Diagnostic Accuracy of Truncal Ataxia and HINTS as Cardinal Signs for Acute Vestibular Syndrome

    PubMed Central

    Carmona, Sergio; Martínez, Carlos; Zalazar, Guillermo; Moro, Marcela; Batuecas-Caletrio, Angel; Luis, Leonel; Gordon, Carlos

    2016-01-01

    The head impulse, nystagmus type, test of skew (HINTS) protocol set a new paradigm to differentiate peripheral vestibular disease from stroke in patients with acute vestibular syndrome (AVS). The relationship between degree of truncal ataxia and stroke has not been systematically studied in patients with AVS. We studied a group of 114 patients who were admitted to a General Hospital due to AVS, 72 of them with vestibular neuritis (based on positive head impulse, abnormal caloric tests, and negative MRI) and the rest with stroke: 32 in the posterior inferior cerebellar artery (PICA) territory (positive HINTS findings, positive MRI) and 10 in the anterior inferior cerebellar artery (AICA) territory (variable findings and grade 3 ataxia, positive MRI). Truncal ataxia was measured by independent observers as grade 1, mild to moderate imbalance with walking independently; grade 2, severe imbalance with standing, but cannot walk without support; and grade 3, falling at upright posture. When we applied the HINTS protocol to our sample, we obtained 100% sensitivity and 94.4% specificity, similar to previously published findings. Only those patients with stroke presented with grade 3 ataxia. Of those with grade 2 ataxia (n = 38), 11 had cerebellar stroke and 28 had vestibular neuritis, not related to the patient’s age. Grade 2–3 ataxia was 92.9% sensitive and 61.1% specific to detect AICA/PICA stroke in patients with AVS, with 100% sensitivity to detect AICA stroke. In turn, two signs (nystagmus of central origin and grade 2–3 Ataxia) had 100% sensitivity and 61.1% specificity. Ataxia is less sensitive than HINTS but much easier to evaluate. PMID:27551274

  19. The Diagnostic Accuracy of Truncal Ataxia and HINTS as Cardinal Signs for Acute Vestibular Syndrome.

    PubMed

    Carmona, Sergio; Martínez, Carlos; Zalazar, Guillermo; Moro, Marcela; Batuecas-Caletrio, Angel; Luis, Leonel; Gordon, Carlos

    2016-01-01

    The head impulse, nystagmus type, test of skew (HINTS) protocol set a new paradigm to differentiate peripheral vestibular disease from stroke in patients with acute vestibular syndrome (AVS). The relationship between degree of truncal ataxia and stroke has not been systematically studied in patients with AVS. We studied a group of 114 patients who were admitted to a General Hospital due to AVS, 72 of them with vestibular neuritis (based on positive head impulse, abnormal caloric tests, and negative MRI) and the rest with stroke: 32 in the posterior inferior cerebellar artery (PICA) territory (positive HINTS findings, positive MRI) and 10 in the anterior inferior cerebellar artery (AICA) territory (variable findings and grade 3 ataxia, positive MRI). Truncal ataxia was measured by independent observers as grade 1, mild to moderate imbalance with walking independently; grade 2, severe imbalance with standing, but cannot walk without support; and grade 3, falling at upright posture. When we applied the HINTS protocol to our sample, we obtained 100% sensitivity and 94.4% specificity, similar to previously published findings. Only those patients with stroke presented with grade 3 ataxia. Of those with grade 2 ataxia (n = 38), 11 had cerebellar stroke and 28 had vestibular neuritis, not related to the patient's age. Grade 2-3 ataxia was 92.9% sensitive and 61.1% specific to detect AICA/PICA stroke in patients with AVS, with 100% sensitivity to detect AICA stroke. In turn, two signs (nystagmus of central origin and grade 2-3 Ataxia) had 100% sensitivity and 61.1% specificity. Ataxia is less sensitive than HINTS but much easier to evaluate. PMID:27551274

  20. Hospital Hints

    MedlinePlus

    ... Division of Geriatrics and Clinical Gerontology Division of Neuroscience FAQs Funding Opportunities Intramural Research Program Office of ... have to spend the night in the hospital. Learning more about what to expect and about people ...

  1. Crystallographic studies of the complex of human HINT1 protein with a non-hydrolyzable analog of Ap4A.

    PubMed

    Dolot, Rafał; Kaczmarek, Renata; Sęda, Aleksandra; Krakowiak, Agnieszka; Baraniak, Janina; Nawrot, Barbara

    2016-06-01

    Histidine triad nucleotide-binding protein 1 (HINT1) represents the most ancient and widespread branch in the histidine triad proteins superfamily. HINT1 plays an important role in various biological processes, and it has been found in many species. Here, we report the first structure (at a 2.34Å resolution) of a complex of human HINT1 with a non-hydrolyzable analog of an Ap4A dinucleotide, containing bis-phosphorothioated glycerol mimicking a polyphosphate chain, obtained from a primitive monoclinic space group P21 crystal. In addition, the apo form of hHINT1 at the space group P21 refined to 1.92Å is reported for comparative studies. PMID:26905466

  2. Mississippi: State Policy Brief

    ERIC Educational Resources Information Center

    Corbett, Julie

    2014-01-01

    This brief is one in a series highlighting state policies, regulations, practices, laws, or other tools intended to create the necessary conditions for school and/or district turnaround. Each brief includes an overview of the relevant turnaround tool, its development process, its impact, and lessons learned that could assist other education…

  3. Florida: State Policy Brief

    ERIC Educational Resources Information Center

    Corbett, Julie

    2015-01-01

    This brief is one in a series highlighting state policies, regulations, practices, laws, or other tools intended to create the necessary conditions for school and/or district turnaround. Each brief includes an overview of the relevant turnaround tool, its development process, its impact, and lessons learned that could assist other education…

  4. Brief Interventions for Adolescents

    PubMed Central

    Winters, Ken C

    2016-01-01

    Public health concerns regarding adolescent alcohol and other drug involvement emphasize the need for continuing research to develop and evaluate preventive interventions for use in a variety of settings. This focus includes research on brief interventions. This short commentary piece provides an overview of the brief intervention literature and highlights future directions PMID:27182561

  5. The boy who would be queen: hints and closets on children's television.

    PubMed

    Dennis, Jeffery P

    2009-01-01

    Although American television programs targeted at children and adolescents posit universal heterosexuality and never openly allude to LGBT persons, a content analysis of 102 episodes of 25 contemporary children's programs revealed many examples of resistance to the heteronormative ideology: intimate same-sex friendships; inclusive statements or stage business; scenes that hint at the existence of same-sex desire; gender-transgressive or otherwise gay-stereotyped characters; and jokes and references that require a knowledge of gay culture. The impact of this resistance on viewers is analyzed through fan fiction and artwork, and potential explanations are examined. PMID:19657933

  6. Energy: Conservation, Energy Briefs

    ERIC Educational Resources Information Center

    Nation's Schools and Colleges, 1975

    1975-01-01

    A comprehensive energy conservation program at College of the Holy Cross has saved nearly one-third of the fuel oil and one-fifth of the electricity used at the college; briefs on boilers, lights, design. (Author/MLF)

  7. Performance of bilingual speakers on the English and Spanish versions of the Hearing in Noise Test (HINT).

    PubMed

    Weiss, Deborah; Dempsey, James J

    2008-01-01

    This study compared the performance of bilingual participants on the English and Spanish versions of the Hearing in Noise Test (HINT). The participants were divided into an early bilingual (EB) group and a late bilingual (LB) group based on age of second-language acquisition. All participants acquired Spanish as their first language (L1) and English as a second language (L2). Care was taken to ensure that all participants demonstrated at least a "good competence level" for self-rated speaking, understanding, reading, and writing skills in both English and Spanish. Results revealed superior performance on the Spanish HINT versus the English HINT in both quiet and in noise for both groups of participants. Significant differences in performance were noted for the EB versus the LB participants. A number of possible explanations for superior performance in L1 are provided, and implications for educating students in their L2 are discussed. PMID:18637406

  8. Brief Psychotherapy: Current Status

    PubMed Central

    Castelnuovo-Tedesco, Pietro

    1967-01-01

    In the past decade, stimulated by public concern with issues of mental health, there has been a new spurt of interest in techniques of brief treatment with circumscribed goals. These are applicable to groups as well as to the single patient. There are still differences of opinion about the effectiveness of brief psychotherapy, particularly the lastingness and depth of the results obtained, yet it is often highly beneficial, especially to previously well-functioning individuals who are involved in a situational crisis. Although probably the best results of brief psychotherapy are with disturbances of moderate severity and recent onset, in practice, it is often tried with a wide spectrum of patients. Brief psychotherapy aims at relief of the patient's major current conflicts rather than at change of his personality structure, which generally requires long-term treatment. Brief psychotherapy is of special relevance for the general physician because the patients whom he sees in large numbers are precisely those best suited for this form of treatment. PMID:6075465

  9. HINT1 peptide/Hsp70 complex induces NK-cell-dependent immunoregulation in a model of autoimmune demyelination.

    PubMed

    Galazka, Grazyna; Jurewicz, Anna; Domowicz, Malgorzata; Cannella, Barbara; Raine, Cedric S; Selmaj, Krzysztof

    2014-10-01

    Heat shock proteins (Hsps) interact with the immune system and have been shown to contribute to immunoregulation. As efficient chaperones, Hsps bind many peptides and these complexes have many yet-to-be-clarified functions. We have shown that Hsp70 is complexed within the mouse CNS with peptide CLAFHDISPQAPTHFLVIPK derived from histidine triad nucleotide-binding protein-1 (HINT1₃₈₋₅₇/Hsp70). Only this complex, in contrast to other peptides complexed with Hsp70, was able to prevent experimental autoimmune encephalomyelitis (EAE) by induction of immunoregulatory mechanisms dependent on NK cells. Pretreatment of proteolipid protein peptide ₁₃₉₋₁₅₁(PLP₁₃₉₋₁₅₁) sensitized SJL/J mice with HINT1₃₈₋₅₇/Hsp70 prevented the development of EAE, suppressed PLP₁₃₉₋₁₅₁-induced T-cell proliferation, and blocked secretion of IL-17. HINT1₃₈₋₅₇ /Hsp70 stimulation of NK cells depended on synergistic activation of two NK-cell receptors, CD94 and NKG2D. NK cells with depleted CD94 or with blocked NKG2D did not inhibit PLP₁₃₉₋₁₅₁-induced spleen cell (SC) proliferation. The HINT1₃₈₋₅₇/Hsp70 complex enhanced surface expression of the NKG2D ligand-H60. Downstream signaling of CD94 and NKG2D converged at the adaptor proteins DAP10 and DAP12, and in response to HINT1₃₈₋₅₇ /Hsp70 stimulation, expression of DAP10 and DAP12 was significantly increased in NK cells. Thus, we have shown that the HINT1₃₈₋₅₇ /Hsp70 complex affects NK-cell function by enhancing NK-cell-dependent immunoregulation in the EAE model of autoimmune demyelination. PMID:25092109

  10. A megaxion at 750 GeV as a first hint of low scale string theory

    NASA Astrophysics Data System (ADS)

    Ibáñez, Luis E.; Martín-Lozano, Víctor

    2016-07-01

    Low scale string models naturally have axion-like pseudoscalars which couple directly to gluons and photons (but not W 's) at tree level. We show how they typically get tree level masses in the presence of closed string fluxes , consistent with the axion discrete gauge symmetry, in a way akin of the axion monodromy of string inflation and relaxion models. We discuss the possibility that the hints for a resonance at 750 GeV recently reported at ATLAS and CMS could correspond to such a heavy axion state ( megaxion). Adjusting the production rate and branching ratios suggest the string scale to be of order M s ≃ 7-104 TeV, depending on the compactification geometry. If this interpretation was correct, one extra Z' gauge boson could be produced before reaching the string threshold at LHC and future colliders.

  11. Technical hints and potential pitfalls in modified radical neck dissection for thyroid cancer

    PubMed Central

    Lorente, Leyre; Sancho, Juan J.

    2013-01-01

    Modified radical neck dissection (MRND) is often performed in conjunction with total thyroidectomy for the management of thyroid cancer. Prevention of postoperative sequelae after MRND is closely dependent on the avoidance of technical mistakes that may lead to significant complications and long-term morbidity. A thorough technical discussion with emphasis on potential pitfalls is made of the most relevant steps of MRND using the extrafascial approach: fascial dissection, approach to the accessory nerve, posterior limits, upper internal jugular vein (IJV), transverse cervical vessels, thoracic duct and compartment V dissection. Some anatomical hints are emphasized to help the novice surgeon to develop a refined surgical technique, the key to an uneventful postoperative course. PMID:25083480

  12. Phase transitions in hydrophobe/phospholipid mixtures: hints at connections between pheromones and anaesthetic activity.

    PubMed

    Borsacchi, Silvia; Geppi, Marco; Macchi, Sara; Ninham, Barry W; Fratini, Emiliano; Ambrosi, Moira; Baglioni, Piero; Lo Nostro, Pierandrea

    2016-06-01

    The phase behavior of a mixture of a typical insect pheromone (olean) and a phospholipid (DOPC)/water dispersion is extensively explored through SAXS, NMR and DSC experiments. The results mimic those obtained with anaesthetics in phospholipid/water systems. They also mimic the behavior and microstructure of ternary mixtures of a membrane mimetic, bilayer-forming double chained surfactants, oils and water. Taken together with recent models for conduction of the nervous impulse, all hint at lipid involvement and the underlying unity in mechanisms of pheromone, anaesthetic and hydrophobic drugs, where a local phase change in the lipid membrane architecture may be at least partly involved in the transmission of the signal. PMID:27210443

  13. NASA educational briefs

    NASA Technical Reports Server (NTRS)

    Vogt, G. L.

    1982-01-01

    In response to a large public demand for information, the Educational Services Branch of NASA has undertaken a series of publications designed for use by teachers, titled 'Educational Briefs for the Classroom', which has resulted in six to eight issues each year for the last three years. Typical of the topics to which the series is dedicated have been space suits, manned spaceflight mission summaries, solar cells, planetary encounter data, orbits, and rocketry. The planning committee for Educational Briefs is aided in its selection of topics by the many letters received by NASA. Following the Voyager Saturn flybys, NASA received more than 175,000 letters from both children and adults.

  14. Brief inpatient psychotherapeutic technique.

    PubMed

    Stein, Michelle B; Jacobo, Michelle C

    2013-09-01

    Trainees rotate onto the medical psychiatric inpatient unit at Massachusetts General Hospital every 6 weeks to learn how to conduct brief inpatient psychotherapy from two staff psychologists and one staff psychiatrist. This article focuses on four key therapeutic principles/techniques used when teaching these trainees about brief inpatient psychotherapy. These include support, affective experience and expression, chain analysis, and identification of relational styles/maladaptive relational patterns. We also briefly discuss our approach to training. Theoretical rationale, numerous clinical examples, and empirical support (of inpatient psychotherapy) are provided. PMID:24000872

  15. A Brief Demographic Portrait

    ERIC Educational Resources Information Center

    Nieto, Sonia

    2012-01-01

    This article presents a brief demographic portrait, with particular emphasis on school-related issues, that points to the dire situation of Latino/a education. According to the 2010 Census, the number of Hispanics (the term used in government data) currently was 50,477,594 million, an increase of 43 percent since 2000, making this group the…

  16. Classroom Management. Brief

    ERIC Educational Resources Information Center

    National Education Association Research Department, 2006

    2006-01-01

    In learning-centered classrooms, the emphasis of classroom management shifts from maintaining behavioral control to fostering student engagement and self-regulation as well as community responsibility. This brief describes classroom management in "learning centered" classrooms, where practices are consistent with recent research knowledge about…

  17. The 2009 Legislative Briefing

    ERIC Educational Resources Information Center

    Gaines, Gale F., Comp.

    2009-01-01

    "The 2009 Legislative Briefing" is a topical summary of actions during the 2009 legislative sessions that affect education in the 16 SREB states. Topics include: state budgets and the economy; tax and revenue; teacher and faculty pay raises; retirement systems; issues affecting teachers and education leaders; health and safety; standards,…

  18. Superintendent's Briefing Book, 2010

    ERIC Educational Resources Information Center

    Educational Research Service, 2009

    2009-01-01

    The "2010 Superintendent's Briefing Book" provides comprehensive yet concise overviews of the best thinking available on a wide range of top-priority PreK-12 education concerns. This resource will prove invaluable in making research-based decisions with confidence, and in identifying programs and practices that will improve student achievement.…

  19. Superintendent's Briefing Book, 2011

    ERIC Educational Resources Information Center

    Educational Research Service, 2010

    2010-01-01

    The "2011 Superintendent's Briefing Book" provides comprehensive yet concise overviews of the best thinking available on a wide range of top-priority PreK-12 education concerns. This resource will prove invaluable in making research-based decisions with confidence, and in identifying programs and practices that will improve student achievement.…

  20. Research in Brief.

    ERIC Educational Resources Information Center

    Journalism Quarterly, 1980

    1980-01-01

    Eight brief research reports concerning a newspaper's conversion to VDTs, media evaluation by police chiefs, defending and indemnifying reporters in tort actions, newsmagazine coverage of the Supreme Court, pricing of advertising in weekly newspapers, the importance of writing, "yeasaying" in readership surveys, and public service utilization by…

  1. 2011 SREB Legislative Briefing

    ERIC Educational Resources Information Center

    Gaines, Gale F., Comp.

    2011-01-01

    The "2011 Legislative Briefing" is a topical summary of state budget and legislative actions that affect elementary, secondary and higher education across the Southern Regional Education Board (SREB) region. It outlines actions in areas such as tax and spending legislation, assistance to local districts, tuition and fees, student financial…

  2. Research in Brief.

    ERIC Educational Resources Information Center

    Journalism Quarterly, 1982

    1982-01-01

    Offers brief descriptions of research concerning (1) media bias toward business, (2) foreign affairs coverage in elite and mass periodicals, (3) how emphasis on people affects coverage of crime, (4) antisocial and prosocial behavior on prime-time television, (5) network news coverage of Iran, and (6) magazines' reporting on insects. (FL)

  3. A Brief History.

    ERIC Educational Resources Information Center

    Yalouris, Nicolaos

    1996-01-01

    Provides a brief but concise overview of the historical development of the Olympic Games in ancient Greece. Originally conceived as a one day, single-race event, the Games grew to the point where they represented an apotheosis of Greek culture. Discusses the role played by conflict within the city-states. (MJP)

  4. Issue Brief on Diversity

    ERIC Educational Resources Information Center

    Division on Developmental Disabilities, Council for Exceptional Children (NJ1), 2013

    2013-01-01

    During the past year, the Diversity Committee of the Division of Developmental Disabilities (DDD) Board worked with the Board and the Issues Committee Chair to develop an issue brief addressing diversity, its impact on the membership and the wider community that is served by the work of DDD, resulting in recommendations that will influence policy…

  5. The 2007 Legislative Briefing

    ERIC Educational Resources Information Center

    Grove, Jeffrey; Gaines, Gale F., Comp.

    2007-01-01

    "The 2007 Legislative Briefing" is a topical summary of actions during the 2006 legislative sessions that affect education in the 16 SREB states. Topics include state budgets and the economy, tax and revenue, school finance, teacher compensation, licensure, certification and evaluation of teachers, strengthening elementary and secondary education,…

  6. Informatics: A Brief Survey.

    ERIC Educational Resources Information Center

    He, Shaoyi

    2003-01-01

    Provides a brief survey of informatics, defined as the application of information technology to various fields, with respect to its historical background, disciplinary identity, fundamental aspects, applications, and challenges. Highlights include biological, clinical, dental, environmental, geomatics, health, legal, management, medical, museum,…

  7. Academic Bankruptcy. Policy Brief.

    ERIC Educational Resources Information Center

    Anderson, Amy Berk; Lewis, Anne C.

    In an effort to improve student achievement in low-performing districts, 22 states have developed academic bankruptcy laws, allowing them to intervene in districts that consistently fail to satisfy state education performance standards. This policy brief presents an overview of these statutes. The text offers a comparative summary of state…

  8. Research in Brief.

    ERIC Educational Resources Information Center

    Journalism Quarterly, 1983

    1983-01-01

    Brief research reports discuss (1) the Greek mass media, (2) media use and student knowledge of current events, (3) brand credibility in advertising, (4) the accuracy in news magazines' forecasts, (5) camera bans in court rooms, (6) education reporting in the Los Angeles "Times," and (7) loneliness, depression, and the uses of television. (FL)

  9. What Does the Public Know about Preventing Cancer? Results from the Health Information National Trends Survey (HINTS)

    ERIC Educational Resources Information Center

    Hawkins, Nikki A.; Berkowitz, Zahava; Peipins, Lucy A.

    2010-01-01

    This study provides information about the public's familiarity with cancer prevention strategies and examines the association between this familiarity and actual prevention behavior. Data from interviews with 5,589 adults included in the 2003 Health Information National Trends Survey (HINTS) were analyzed. Most respondents were able to cite one or…

  10. Updating and Maintaining School Emergency Management Plans. Helpful Hints for School Emergency Management. Volume 2, Issue 3, 2007

    ERIC Educational Resources Information Center

    US Department of Education, 2007

    2007-01-01

    "Helpful Hints" offers a quick overview of school emergency preparedness topics that are frequently the subject of inquiries. Developing and implementing comprehensive, multi-hazard emergency management plans is an ongoing process that must be consistently reinforced and strengthened. Opportunities for reviewing, strengthening and updating…

  11. Cybernetics of Brief Family Therapy.

    ERIC Educational Resources Information Center

    Keeney, Bradford P.; Ross, Jeffrey M.

    1983-01-01

    Presents a cybernetic view of brief family therapy. Includes a historical discussion of the key ideas underlying brief family therapy, a cybernetic model of therapeutic change, and a clinical case for exemplification. (Author/JAC)

  12. Generic School Grounds Design Brief.

    ERIC Educational Resources Information Center

    Dorset County Council, Dorchester (England).

    This document was produced to provide architects, planners, and builders with an educational design brief for Dorset, England school grounds. The County Education Planning and Development Department will use it as an educational and curriculum statement to complement their more detailed and specific building briefs. The brief uses many of the…

  13. The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: Implications in neurological disorders

    PubMed Central

    Rodríguez-Muñoz, María; Cortés-Montero, Elsa; Pozo-Rodrigálvarez, Andrea; Sánchez-Blázquez, Pilar; Garzón-Niño, Javier

    2015-01-01

    In the brain, the histidine triad nucleotide-binding protein 1 (HINT1) and sigma 1 receptors (σ1Rs) coordinate the activity of certain G-protein coupled receptors (GPCRs) with that of glutamate N-methyl-D-aspartate receptors (NMDARs). To determine the role of HINT1-σ1R in the plasticity of GPCR-NMDAR interactions, substances acting at MOR, cannabinoid CB1 receptor, NMDAR and σ1R were injected into mice, and their effects were evaluated through in vivo, ex vivo, and in vitro assays. It was observed that HINT1 protein binds to GPCRs and NMDAR NR1 subunits in a calcium-independent manner, whereas σ1R binding to these proteins increases in the presence of calcium. In this scenario, σ1R agonists keep HINT1 at the GPCR and stimulate GPCR-NMDAR interaction, whereas σ1R antagonists transfer HINT1 to NR1 subunits and disengage both receptors. This regulation is lost in σ1R−/− mice, where HINT1 proteins mostly associate with NMDARs, and GPCRs are physically and functionally disconnected from NMDARs. In HINT1−/− mice, ischemia produces low NMDAR-mediated brain damage, suggesting that several different GPCRs enhance glutamate excitotoxicity via HINT1-σ1R. Thus, several GPCRs associate with NMDARs by a dynamic process under the physiological control of HINT1 proteins and σ1Rs. The NMDAR-HINT1-σ1R complex deserves attention because it offers new therapeutic opportunities. PMID:26461475

  14. Alcohol brief interventions.

    PubMed

    Finfgeld-Connett, Deborah

    2005-01-01

    A large proportion of Americans report binge or heavy drinking. The human and economic costs of alcohol misuse are extensive, with hundreds of thousands of lives lost or disrupted and billions of dollars spent due to impaired productivity, crime, and adverse health consequences. In an effort to reduce costs such as these, scientists and clinicians have developed brief interventions, characterized by their low intensity and short (5-60 minutes) duration, as well as by their intent to provide early intervention before drinkers develop alcohol abuse or dependence. The purpose of this review, therefore, is to analyze research studies related to brief intervention and critically analyze and critique their findings. In addition, both prospective randomized controlled trials and meta-analyses will be used to discuss the implications for clinical practice and make recommendations for future research. PMID:16350770

  15. NASA tech brief evaluations

    NASA Technical Reports Server (NTRS)

    Workman, Gary L.

    1994-01-01

    A major step in transferring technology is to disseminate information about new developments to the appropriate sector(s). A useful vehicle for transferring technology from the government sector to industry has been demonstrated with the use of periodical and journal announcements to highlight technological achievements which may meet the needs of industries other than the one who developed the innovation. To meet this end, NASA has very successfully pursued the goal of identifying technical innovations through the national circulation publication; NASA Tech Briefs. At one time the Technology Utilization Offices of the various centers coordinated the selection of appropriate technologies through a common channel. In recent years, each NASA field center has undertaken the task of evaluating submittals for Tech Brief publication independently of the others. The University of Alabama in Huntsville was selected to assist MSFC in evaluating technology developed under the various programs managed by the NASA center for publication in the NASA Tech Briefs journal. The primary motivation for the NASA Tech Briefs publication is to bring to the attention of industry the various NASA technologies which, in general, have been developed for a specific aerospace requirement, but has application in other areas. Since there are a number of applications outside of NASA that can benefit from innovative concepts developed within the MSPC programs, the ability to transfer technology to other sectors is very high. In most cases, the innovator(s) are not always knowledgeable about other industries which might potentially benefit from their innovation. The evaluation process can therefore contribute to the list of potential users through a knowledgeable evaluator.

  16. Strategic forces briefing

    SciTech Connect

    Bing, G.; Chrzanowski, P.; May, M.; Nordyke, M.

    1989-04-06

    The Strategic Forces Briefing'' is our attempt, accomplished over the past several months, to outline and highlight the more significant strategic force issues that must be addressed in the near future. Some issues are recurrent: the need for an effective modernized Triad and a constant concern for force survivability. Some issues derive from arms control: the Strategic Arms Reduction Talks (SALT) are sufficiently advanced to set broad numerical limits on forces, but not so constraining as to preclude choices among weapon systems and deployment modes. Finally, a new administration faced with serious budgetary problems must strive for the most effective strategic forces limited dollars can buy and support. A review of strategic forces logically begins with consideration of the missions the forces are charged with. We begin the briefing with a short review of targeting policy and implementation within the constraints of available unclassified information. We then review each element of the Triad with sections on SLBMs, ICBMs, and Air-Breathing (bomber and cruise missile) systems. A short section at the end deals with the potential impact of strategic defense on offensive force planning. We consider ABM, ASAT, and air defense; but we do not attempt to address the technical issues of strategic defense per se. The final section gives a brief overview of the tritium supply problem. We conclude with a summary of recommendations that emerge from our review. The results of calculation on the effectiveness of various weapon systems as a function of cost that are presented in the briefing are by Paul Chrzanowski.

  17. 4 CFR 28.60 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 4 Accounts 1 2011-01-01 2011-01-01 false Briefs. 28.60 Section 28.60 Accounts GOVERNMENT... Hearings § 28.60 Briefs. (a) Length. Principal briefs shall not exceed 60 pages and reply briefs 30 pages... extended briefs shall be granted only for good cause shown. Briefs in excess of 10 pages shall include...

  18. 12 CFR 622.14 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Briefs. 622.14 Section 622.14 Banks and Banking... Formal Hearings § 622.14 Briefs. (a) Contents. Any brief filed in a proceeding shall be confined to the... briefs. Reply briefs may be filed within 10 days after service of original briefs of opposing...

  19. 4 CFR 28.60 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Briefs. 28.60 Section 28.60 Accounts GOVERNMENT... Hearings § 28.60 Briefs. (a) Length. Principal briefs shall not exceed 60 pages and reply briefs 30 pages... extended briefs shall be granted only for good cause shown. Briefs in excess of 10 pages shall include...

  20. 12 CFR 622.14 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Briefs. 622.14 Section 622.14 Banks and Banking... Formal Hearings § 622.14 Briefs. (a) Contents. Any brief filed in a proceeding shall be confined to the... briefs. Reply briefs may be filed within 10 days after service of original briefs of opposing...

  1. Diagnosing Stroke in Acute Vertigo: The HINTS Family of Eye Movement Tests and the Future of the "Eye ECG".

    PubMed

    Newman-Toker, David E; Curthoys, Ian S; Halmagyi, G Michael

    2015-10-01

    Patients who present to the emergency department with symptoms of acute vertigo or dizziness are frequently misdiagnosed. Missed opportunities to promptly treat dangerous strokes can result in poor clinical outcomes. Inappropriate testing and incorrect treatments for those with benign peripheral vestibular disorders leads to patient harm and unnecessary costs. Over the past decade, novel bedside approaches to diagnose patients with the acute vestibular syndrome have been developed and refined. A battery of three bedside tests of ocular motor physiology known as "HINTS" (head impulse, nystagmus, test of skew) has been shown to identify acute strokes more accurately than even magnetic resonance imaging with diffusion-weighted imaging (MRI-DWI) when applied in the early acute period by eye-movement specialists. Recent advances in lightweight, high-speed video-oculography (VOG) technology have made possible a future in which HINTS might be applied by nonspecialists in frontline care settings using portable VOG. Use of technology to measure eye movements (VOG-HINTS) to diagnose stroke in the acute vestibular syndrome is analogous to the use of electrocardiography (ECG) to diagnose myocardial infarction in acute chest pain. This "eye ECG" approach could transform care for patients with acute vertigo and dizziness around the world. In the United States alone, successful implementation would likely result in improved quality of emergency care for hundreds of thousands of peripheral vestibular patients and tens of thousands of stroke patients, as well as an estimated national health care savings of roughly $1 billion per year. In this article, the authors review the origins of the HINTS approach, empiric evidence and pathophysiologic principles supporting its use, and possible uses for the eye ECG in teleconsultation, teaching, and triage. PMID:26444396

  2. NASA Agency Overview Briefing

    NASA Technical Reports Server (NTRS)

    2006-01-01

    The briefing opened with Dean Acosta (NASA Press Secretary) introducing Michael Griffin (NASA Administrator) and Bill Gerstenmaier (Associate Administrator for Space Operations). Bill Griffin stated that they would resume the Shuttle Fight to Return process, that the vehicle was remarkably clean and if the weather was good, the Shuttle would be ready to launch as scheduled. Bill Gerstenmaier stated that the preparations and processing of the vehicle went extremely well and they are looking forward to increasing the crew size to three. Then the floor was open to questions from the press.

  3. Hurricane Gilbert briefing

    NASA Astrophysics Data System (ADS)

    Bush, Susan M.

    Hurricane Gilbert has been called one of the most monstrous hurricanes of the 20th century, cutting a nearly 2000-mile swath across Jamaica, Mexico's Yucatan Peninsula, and along the border of Texas and Mexico September 10-17. Death toll was about 200, and damage estimates were above $8 billion.A briefing on the effects of Gilbert was held in Washington, D.C., on October 24. It was sponsored by the Committee on Natural Disasters of the National Academy of Sciences, with the Office of U.S. Foreign Disaster Assistance and the National Oceanic and Atmospheric Administration.

  4. Recent developments: Industry briefs

    SciTech Connect

    1992-04-01

    This article is the `Industry Briefs` portion of Nuexco`s April 1992 `Recent Developments` section. Items covered in this article include: (1) France`s SILVA enrichment process, (2) 1993 US enrichment prices, (3) relicensing plans for Monticello, (4) a reactor incident at Sosnovy Bor 3, (5) Canadian agreements on Uranium mining, (6) China`s ascession to the Nuclear Non-proliferation Treaty, (7) settlement of the lawsuit between Westinghouse and the Philipines, (8) political reforms on South Africa, and (9) establishment of an international agreement on dual-use export control policy.

  5. Neurolaw: A brief introduction

    PubMed Central

    Petoft, Arian

    2015-01-01

    Neurolaw, as an interdisciplinary field which links the brain to law, facilitates the pathway to better understanding of human behavior in order to regulate it accurately through incorporating neuroscience achievements in legal studies. Since 1990’s, this emerging field, by study on human nervous system as a new dimension of legal phenomena, leads to a more precise explanation for human behavior to revise legal rules and decision-makings. This paper strives to bring about significantly a brief introduction to neurolaw so as to take effective steps toward exploring and expanding the scope of law and more thorough understanding of legal issues in the field at hand. PMID:25874060

  6. ALMA HINTS AT THE PRESENCE OF TWO COMPANIONS IN THE DISK AROUND HD 100546

    SciTech Connect

    Walsh, Catherine; Juhász, Attila; Pinilla, Paola; Harsono, Daniel; Mathews, Geoffrey S.; Hogerheijde, Michiel R.; Dent, William R. F.; Birnstiel, T.; Meeus, Gwendolyn; Nomura, Hideko; Aikawa, Yuri; Millar, T. J.; Sandell, Göran

    2014-08-10

    HD 100546 is a well-studied Herbig Be star-disk system that likely hosts a close-in companion with compelling observational evidence for an embedded protoplanet at 68 AU. We present Atacama Large Millimeter/Submillimeter Array observations of the HD 100546 disk which resolve the gas and dust structure at (sub)millimeter wavelengths. The CO emission (at 345.795 GHz) originates from an extensive molecular disk (390 ± 20 AU in radius) whereas the continuum emission is more compact (230 ± 20 AU in radius), suggesting radial drift of the millimeter-sized grains. The CO emission is similar in extent to scattered light images indicating well-mixed gas and micrometer-sized grains in the disk atmosphere. Assuming azimuthal symmetry, a single-component power-law model cannot reproduce the continuum visibilities. The visibilities and images are better reproduced by a double-component model: a compact ring with a width of 21 AU centered at 26 AU and an outer ring with a width of 75 ± 3 AU centered at 190 ± 3 AU. The influence of a companion and protoplanet on the dust evolution is investigated. The companion at 10 AU facilitates the accumulation of millimeter-sized grains within a compact ring, ≈20-30 AU, by ≈10 Myr. The injection of a protoplanet at 1 Myr hastens the ring formation (≈1.2 Myr) and also triggers the development of an outer ring (≈100-200 AU). These observations provide additional evidence for the presence of a close-in companion and hint at dynamical clearing by a protoplanet in the outer disk.

  7. Discovery at Young Star Hints Magnetism Common to All Cosmic Jets

    NASA Astrophysics Data System (ADS)

    2010-11-01

    Astronomers have found the first evidence of a magnetic field in a jet of material ejected from a young star, a discovery that points toward future breakthroughs in understanding the nature of all types of cosmic jets and of the role of magnetic fields in star formation. Throughout the Universe, jets of subatomic particles are ejected by three phenomena: the supermassive black holes at the cores of galaxies, smaller black holes or neutron stars consuming material from companion stars, and young stars still in the process of gathering mass from their surroundings. Previously, magnetic fields were detected in the jets of the first two, but until now, magnetic fields had not been confirmed in the jets from young stars. "Our discovery gives a strong hint that all three types of jets originate through a common process," said Carlos Carrasco-Gonzalez, of the Astrophysical Institute of Andalucia Spanish National Research Council (IAA-CSIC) and the National Autonomous University of Mexico (UNAM). The astronomers used the National Science Foundation's Very Large Array (VLA) radio telescope to study a young star some 5,500 light-years from Earth, called IRAS 18162-2048. This star, possibly as massive as 10 Suns, is ejecting a jet 17 light-years long. Observing this object for 12 hours with the VLA, the scientists found that radio waves from the jet have a characteristic indicating they arose when fast-moving electrons interacted with magnetic fields. This characteristic, called polarization, gives a preferential alignment to the electric and magnetic fields of the radio waves. "We see for the first time that a jet from a young star shares this common characteristic with the other types of cosmic jets," said Luis Rodriguez, of UNAM. The discovery, the astronomers say, may allow them to gain an improved understanding of the physics of the jets as well as of the role magnetic fields play in forming new stars. The jets from young stars, unlike the other types, emit radiation

  8. SOHO Mission Science Briefing

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Footage shows the SOHO Mission Pre-Launch Science Briefing. The moderator of the conference is Fred Brown, NASA/GSFC Public Affairs, introduces the panel members. Included are Professor Roger Bonnet, Director ESA Science Program, Dr. Wesley Huntress, Jr., NASA Associate Administrator for Space Science and Dr. Vicente Domingo, ESA SOHO Project Scientist. Also present are several members from the SOHO Team: Dr. Richard Harrison, Art Poland, and Phillip Scherrer. The discussions include understanding the phenomena of the sun, eruption of gas clouds into the atmosphere, the polishing of the mirrors for the SOHO satellite, artificial intelligence in the telescopes, and the launch and operating costs. The panel members are also seen answering questions from various NASA Centers and Paris.

  9. A Brief Taxometrics Primer

    PubMed Central

    Beauchaine, Theodore P.

    2009-01-01

    Taxometric procedures provide an empirical means of determining which psychiatric disorders are typologically distinct from normal behavioral functioning. Although most disorders reflect extremes along continuously distributed behavioral traits, identifying those that are discrete has important implications for accurate diagnosis, effective treatment, early identification of risk, and improved understanding of etiology. This article provides (a) brief descriptions of the conceptual bases of several taxometric procedures, (b) example analyses using simulated data, and (c) strategies for avoiding common pitfalls that are often observed in taxometrics research. To date, most taxometrics studies have appeared in the adult psychopathology literature. It is hoped that this primer will encourage interested readers to extend taxometrics research to child and adolescent populations. PMID:18088222

  10. Galileo Mission Science Briefing

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The first of two tapes of the Galileo Mission Science press briefing is presented. The panel is moderated by George Diller from the Kennedy Space Center (KSC) Public Affairs Office. The participants are John Conway, the director of Payload and operations at Kennedy; Donald E. Williams, Commander of STS-43, the shuttle mission which will launch the Galileo mission; John Casani, the Deputy Assistant Director of Flight Projects at the Jet Propulsion Lab (JPL); Dick Spehalski, Galileo Project Manager at JPL; and Terrence Johnson, Galileo Project Scientist at JPL. The briefing begins with an announcement of the arrival of the Galileo Orbiter at KSC. The required steps prior to the launch are discussed. The mission trajectory and gravity assists from planetary and solar flybys are reviewed. Detailed designs of the orbiter are shown. The distance that Galileo will travel from the sun precludes the use of solar energy for heat. Therefore Radioisotope heater units are used to keep the equipment at operational temperature. A video of the arrival of the spacecraft at KSC and final tests and preparations is shown. Some of the many science goals of the mission are reviewed. Another video showing an overview of the Galileo mission is presented. During the question and answer period, the issue of the use of plutonium on the mission is broached, which engenders a review of the testing methods used to ensure the safety of the capsules containing the hazardous substance. This video has actual shots of the orbiter, as it is undergoing the final preparations and tests for the mission.

  11. 17 CFR 9.23 - Answering brief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Answering brief. 9.23 Section... Appeals § 9.23 Answering brief. (a) Time for filing answering brief. Within thirty days after service of the appeal brief, the exchange must file with the Commission an answering brief. (b) Contents...

  12. 7 CFR 15.135 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Posthearing briefs. 15.135 Section 15.135 Agriculture... Posthearing briefs. The hearing officer shall fix a reasonable time for filing posthearing briefs, which may contain proposed findings of fact and conclusions of law, and, if permitted, reply briefs. Briefs...

  13. 24 CFR 1720.615 - Reply brief.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Reply brief. 1720.615 Section 1720... Proceedings Appeals § 1720.615 Reply brief. A brief in reply to an answering brief, limited to rebuttal of matters in the answering brief, may be filed and served by a party within 7 days after receipt of...

  14. 17 CFR 9.23 - Answering brief.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Answering brief. 9.23 Section... Appeals § 9.23 Answering brief. (a) Time for filing answering brief. Within thirty days after service of the appeal brief, the exchange must file with the Commission an answering brief. (b) Contents...

  15. 24 CFR 1720.615 - Reply brief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Reply brief. 1720.615 Section 1720... Proceedings Appeals § 1720.615 Reply brief. A brief in reply to an answering brief, limited to rebuttal of matters in the answering brief, may be filed and served by a party within 7 days after receipt of...

  16. 7 CFR 15.135 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Posthearing briefs. 15.135 Section 15.135 Agriculture... Posthearing briefs. The hearing officer shall fix a reasonable time for filing posthearing briefs, which may contain proposed findings of fact and conclusions of law, and, if permitted, reply briefs. Briefs...

  17. New Mexico: State Policy Brief

    ERIC Educational Resources Information Center

    Corbett, Julie

    2015-01-01

    This brief is one in a series highlighting state policies, regulations, practices, laws, or other tools intended to create the necessary conditions for school and/or district turnaround. Each brief includes an overview of the relevant turnaround tool, its development process, its impact, and lessons learned that could assist other education…

  18. Performance-Based Funding Brief

    ERIC Educational Resources Information Center

    Washington Higher Education Coordinating Board, 2011

    2011-01-01

    A number of states have made progress in implementing performance-based funding (PFB) and accountability. This policy brief summarizes main features of performance-based funding systems in three states: Tennessee, Ohio, and Indiana. The brief also identifies key issues that states considering performance-based funding must address, as well as…

  19. Believing and Achieving. Issue Brief

    ERIC Educational Resources Information Center

    Jerald, Craig D.

    2007-01-01

    This research brief takes a look at the role of teacher efficacy-how teachers' beliefs in their own abilities affect student achievement. The brief examines the influence of perceived efficacy and building teacher confidence (social persuasion, collegiality, and shared decision making). It concludes by asserting that more positive steps must be…

  20. PsHint1, associated with the G-protein α subunit PsGPA1, is required for the chemotaxis and pathogenicity of Phytophthora sojae.

    PubMed

    Zhang, Xin; Zhai, Chunhua; Hua, Chenlei; Qiu, Min; Hao, Yujuan; Nie, Pingping; Ye, Wenwu; Wang, Yuanchao

    2016-02-01

    Zoospore chemotaxis to soybean isoflavones is essential in the early stages of infection by the oomycete pathogen Phytophthora sojae. Previously, we have identified a G-protein α subunit encoded by PsGPA1 which regulates the chemotaxis and pathogenicity of P. sojae. In the present study, we used affinity purification to identify PsGPA1-interacting proteins, including PsHint1, a histidine triad (HIT) domain-containing protein orthologous to human HIT nucleotide-binding protein 1 (HINT1). PsHint1 interacted with both the guanosine triphosphate (GTP)- and guanosine diphosphate (GDP)-bound forms of PsGPA1. An analysis of the gene-silenced transformants revealed that PsHint1 was involved in the chemotropic response of zoospores to the isoflavone daidzein. During interaction with a susceptible soybean cultivar, PsHint1-silenced transformants displayed significantly reduced infectious hyphal extension and caused a strong cell death in plants. In addition, the transformants displayed defective cyst germination, forming abnormal germ tubes that were highly branched and exhibited apical swelling. These results suggest that PsHint1 not only regulates chemotaxis by interacting with PsGPA1, but also participates in a Gα-independent pathway involved in the pathogenicity of P. sojae. PMID:25976113

  1. STS-1: Columbia Briefings

    NASA Technical Reports Server (NTRS)

    2006-01-01

    A video presentation on an update of the STS-1 Columbia Shuttle is shown. Hugh Harris is the moderator. He introduces Don Phillips, Chief STS Test OPS, who presents the status of the vehicle. Terry William, Chief of Mechanical Systems, discusses the debonding of the panels. A question and answer period from the news media is shown. The various topics of discussion from the news media include: 1) Repair of thermal tiles; 2) Launch dates; and 3) Landing and launch sites and 4) Low pressure/high pressure tanking tests. An audio presentation is given of questions from NASA Marshall Space Flight Center and NASA Washington. On March 12, 1981, another STS-1 Columbia update is shown. Bob Schick, Shuttle Test Director, and Bob Sieck, Flight Project Engineer answers questions about the actual repair time of the panels and a very detailed description of the three areas of debonding is presented. A brief launch date statement from Dr. Allen Lovelace, Acting NASA Administrator is given and John Lardley, Shuttle Associate Director, discusses the flight readiness review.

  2. 17 CFR 171.26 - Answering brief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Answering brief. 171.26... Denial and Registration Actions § 171.26 Answering brief. (a) Time for filing answering brief. Within thirty days after service of the apeal brief, the National Futures Association shall file with...

  3. 37 CFR 41.67 - Appellant's brief.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Appellant's brief. 41.67... Appellant's brief. (a)(1) Appellant(s) may once, within time limits for filing set forth in § 41.66, file a brief and serve the brief on all other parties to the proceeding in accordance with § 1.903 of...

  4. 43 CFR 4.1273 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Briefs. 4.1273 Section 4.1273 Public Lands... Administrative Law Judges § 4.1273 Briefs. (a) Unless the Board orders otherwise, an appellant's brief is due on... appellant fails to file a timely brief, an appeal under this part may be subject to summary dismissal....

  5. 37 CFR 41.71 - Rebuttal brief.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Rebuttal brief. 41.71 Section... Rebuttal brief. (a) Within one month of the examiner's answer, any appellant may once file a rebuttal brief. (b)(1) The rebuttal brief of the owner may be directed to the examiner's answer and/or any...

  6. 37 CFR 41.68 - Respondent's brief.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Respondent's brief. 41.68... Respondent's brief. (a)(1) Respondent(s) in an appeal may once, within the time limit for filing set forth in § 41.66, file a respondent brief and serve the brief on all parties in accordance with § 1.903 of...

  7. 45 CFR 150.451 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Posthearing briefs. 150.451 Section 150.451 Public... ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS Administrative Hearings § 150.451 Posthearing briefs... posthearing brief. The ALJ will establish the schedule by which such briefs must be filed. The ALJ may...

  8. 21 CFR 17.43 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Posthearing briefs. 17.43 Section 17.43 Food and... PENALTIES HEARINGS § 17.43 Posthearing briefs. Any party may file a posthearing brief. The presiding officer shall fix the time for filing such briefs (which shall be filed simultaneously), which shall not...

  9. 37 CFR 41.71 - Rebuttal brief.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Rebuttal brief. 41.71 Section... Rebuttal brief. (a) Within one month of the examiner's answer, any appellant may once file a rebuttal brief. (b)(1) The rebuttal brief of the owner may be directed to the examiner's answer and/or any...

  10. 43 CFR 4.1273 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Briefs. 4.1273 Section 4.1273 Public Lands... Administrative Law Judges § 4.1273 Briefs. (a) Unless the Board orders otherwise, an appellant's brief is due on... appellant fails to file a timely brief, an appeal under this part may be subject to summary dismissal....

  11. 29 CFR 2700.75 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Briefs. 2700.75 Section 2700.75 Labor Regulations Relating... Commission § 2700.75 Briefs. (a) Time to file—(1) Opening and response briefs. Within 30 days after the Commission grants a petition for discretionary review, the petitioner shall file his opening brief. If...

  12. 20 CFR 802.213 - Reply briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Reply briefs. 802.213 Section 802.213... Procedures Initial Processing § 802.213 Reply briefs. (a) Within 20 days after the receipt of a brief... upon whom it was served may file a brief, memorandum, or other statement in reply to it. (b)...

  13. 24 CFR 1720.610 - Answering brief.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Answering brief. 1720.610 Section... Proceedings Appeals § 1720.610 Answering brief. Within 20 days after service of an appeal brief upon a party, such party may file an answering brief conforming to the requirements of § 1720.620....

  14. 24 CFR 1720.610 - Answering brief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Answering brief. 1720.610 Section... Proceedings Appeals § 1720.610 Answering brief. Within 20 days after service of an appeal brief upon a party, such party may file an answering brief conforming to the requirements of § 1720.620....

  15. 45 CFR 150.451 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Posthearing briefs. 150.451 Section 150.451 Public... ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS Administrative Hearings § 150.451 Posthearing briefs... posthearing brief. The ALJ will establish the schedule by which such briefs must be filed. The ALJ may...

  16. 29 CFR 2700.75 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Briefs. 2700.75 Section 2700.75 Labor Regulations Relating... Commission § 2700.75 Briefs. (a) Time to file—(1) Opening and response briefs. Within 30 days after the Commission grants a petition for discretionary review, the petitioner shall file his opening brief. If...

  17. 21 CFR 17.43 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Posthearing briefs. 17.43 Section 17.43 Food and... PENALTIES HEARINGS § 17.43 Posthearing briefs. Any party may file a posthearing brief. The presiding officer shall fix the time for filing such briefs (which shall be filed simultaneously), which shall not...

  18. 17 CFR 171.26 - Answering brief.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Answering brief. 171.26... Denial and Registration Actions § 171.26 Answering brief. (a) Time for filing answering brief. Within thirty days after service of the apeal brief, the National Futures Association shall file with...

  19. Brief Articles for Latino Parents, 1999 Edition.

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Rural Education and Small Schools, Charleston, WV.

    This packet contains six briefs developed specifically for Spanish-speaking Latino parents, and English translations of the briefs. These briefs state what researchers and practitioners have learned about various ways parents can help their children do well in school. Earlier editions of brief articles for parents have been used in various ways by…

  20. Spanish Language Briefs for Parents, 1995.

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Rural Education and Small Schools, Charleston, WV.

    This packet contains six briefs developed specifically for Spanish-speaking parents of Mexican origin, and English translations of the briefs. In plain language, these briefs state what researchers and practitioners have learned about various ways parents can help their children do well in school. Titles of the briefs are (1) "Apoyando el…

  1. The σ1 Receptor Engages the Redox-Regulated HINT1 Protein to Bring Opioid Analgesia Under NMDA Receptor Negative Control

    PubMed Central

    Rodríguez-Muñoz, María; Sánchez-Blázquez, Pilar; Herrero-Labrador, Raquel; Martínez-Murillo, Ricardo; Merlos, Manuel; Vela, José Miguel

    2015-01-01

    Abstract Aims: The in vivo pharmacology of the sigma 1 receptor (σ1R) is certainly complex; however, σ1R antagonists are of therapeutic interest, because they enhance mu-opioid receptor (MOR)-mediated antinociception and reduce neuropathic pain. Thus, we investigated whether the σ1R is involved in the negative control that glutamate N-methyl-d-aspartate acid receptors (NMDARs) exert on opioid antinociception. Results: The MOR C terminus carries the histidine triad nucleotide-binding protein 1 (HINT1) coupled to the regulator of G-protein signaling RGSZ2-neural nitric oxide synthase assembly. Activated MORs stimulate the production of nitric oxide (NO), and the redox zinc switch RGSZ2 converts this signal into free zinc ions that are required to recruit the redox sensor PKCγ to HINT1 proteins. Then, PKCγ impairs HINT1-RGSZ2 association and enables σ1R-NR1 interaction with MOR-HINT1 complexes to restrain opioid signaling. The inhibition of NOS or the absence of σ1Rs prevents HINT1-PKCγ interaction, and MOR-NMDAR cross-regulation fails. The σ1R antagonists transitorily remove the binding of σ1Rs to NR1 subunits, facilitate the entrance of negative regulators of NMDARs, likely Ca2+-CaM, and prevent NR1 interaction with HINT1, thereby impairing the negative feedback of glutamate on opioid analgesia. Innovation: A redox-regulated process situates MOR signaling under NMDAR control, and in this context, the σ1R binds to the cytosolic C terminal region of the NMDAR NR1 subunit. Conclusion: The σ1R antagonists enhance opioid analgesia in naïve mice by releasing MORs from the negative influence of NMDARs, and they also reset antinociception in morphine tolerant animals. Moreover, σ1R antagonists alleviate neuropathic pain, probably by driving the inhibition of up-regulated NMDARs. Antioxid. Redox Signal. 22, 799–818. PMID:25557043

  2. Brief Psychotherapy in Family Practice

    PubMed Central

    MacDonald, Peter J.; Brown, Alan

    1986-01-01

    A large number of patients with psychosocial or psychiatric disorders present to family physicians, and the family physician needs a model of psychotherapy with which to cope with their problems. A model of brief psychotherapy is presented which is time limited, goal directed and easy to learn. It consists of four facets drawn from established areas of psychotherapy: characteristics of the therapist; characteristics of the patient; Eriksonian developmental stages; and the process of therapy as described by Carkhuff. These facets fit together in a way which is useful to the family physician in managing those patient problems for which brief psychotherapy is indicated. PMID:21267176

  3. Beacons In Brief. P/PV In Brief. Issue 2

    ERIC Educational Resources Information Center

    Blank, Susan; Farley, Chelsea

    2004-01-01

    This second issue in P/PV's "In Brief" series focuses on the San Francisco Beacon Initiative and P/PV's recently released evaluation results. The Beacon Initiative established after-school programs in eight public schools in low-income San Francisco neighborhoods. P/PV's 36-month evaluation examined key developmental and academic outcomes.…

  4. CDC 2004 Programs in Brief.

    ERIC Educational Resources Information Center

    US Department of Health and Human Services, 2004

    2004-01-01

    Grouped in 16 categories, the 2004 Programs in Brief illustrates the scope of Centers for Disease Control and Prevention (CDC) and the Agency for Toxic Substances and Disease Registry (ATSDR) activities, as well as their shared goals of safer, healthier people here and around the world. Each description includes a statement of the public health…

  5. BRIEFING ABOUT SIMCORB BUSINESS PLAN

    EPA Science Inventory

    The SIMCorB Business Plan was discussed at the ORD Infrastructure Meeting held on July 17, 2000 in Washington, D.C.The briefing explained the purpose of the Plan as a vehicle to provide a road map to attain the ORD science IM vision. The road map includes defined milestones, bu...

  6. "Love" and Math. Issue Brief

    ERIC Educational Resources Information Center

    Jerald, Craig D.

    2006-01-01

    This is the first in a series of issue briefs to be written for The Center for Comprehensive School Reform and Improvement during 2006. A longstanding tenet of American education--one built into the very fabric of teacher training and licensure--is that elementary teachers need only general teaching skills and that having a caring personality is…

  7. Zero Tolerance Policies. Research Brief

    ERIC Educational Resources Information Center

    Muir, Mike

    2004-01-01

    Much of this brief comes from the ERIC Digest on Zero Tolerance Policies (ERIC #: ED451579). State legislatures and school boards are adopting a growing number of zero-tolerance polices toward weapons, guns, and violence. Zero-tolerance polices are rules intended to address specific school-safety issues. Despite the controversies that it has…

  8. Brief Note: Response to Benatar.

    PubMed

    Kelland, Lindsay-Ann

    2015-11-01

    In his response to my article entitled 'The Harm of Male-on-Female Rape: A Response to David Benatar', Benatar argues that I take his claims out of context, misrepresent them, and set up a straw man, which means, he claims, that I fail to respond to anything he has actually said. In this brief note, I respond to these allegations. PMID:25592400

  9. KIDS COUNT Data Brief, 2009

    ERIC Educational Resources Information Center

    Annie E. Casey Foundation, 2009

    2009-01-01

    This 2009 KIDS COUNT Data Brief features highlights of the enhanced, mobile-friendly Data Center; data on the 10 key indicators of child well-being for all U.S. states, the District of Columbia, and many cities, counties, and school districts; and a summary of this year's essay, which calls for improvements to the nation's ability to design and…

  10. Phase II Study Proposal Briefs.

    ERIC Educational Resources Information Center

    National Center for the Study of Postsecondary Educational Supports, Honolulu, HI.

    This document collects 23 study proposal briefs presented to the National Center for the Study of Postsecondary Educational Supports. The proposals address the following topics concerned with postsecondary services for students with disabilities: cultural empowerment, longitudinal analysis of postsecondary students' experience, effective models of…

  11. Brief Psychotherapy: The Multimodal Model.

    ERIC Educational Resources Information Center

    Lazarus, Arnold A.

    1989-01-01

    Outlines tenets of multimodal therapy (MMT) and argues for its cost-effective yet comprehensive value as a brief psychotherapy model. Describes MMT as an integrated, seven-modality model of personality and provides clinical examples of its use. Argues that MMT approach will be an important future alternative to more expensive, time-consuming, and…

  12. Summer Bridge Programs. Policy Brief

    ERIC Educational Resources Information Center

    Center for Comprehensive School Reform and Improvement, 2009

    2009-01-01

    Across the nation, school policymakers are grappling with what to do about the increasing numbers of students who do not advance beyond ninth grade. National estimates put the student attrition rate before tenth grade at between 11 and 33 percent, and only about 70 percent of ninth graders make it to graduation. This policy brief focuses on one…

  13. Humans and Robots. Educational Brief.

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration, Washington, DC.

    This brief discusses human movement and robotic human movement simulators. The activity for students in grades 5-12 provides a history of robotic movement and includes making an End Effector for the robotic arms used on the Space Shuttle and the International Space Station (ISS). (MVL)

  14. Mt. SAC Research Briefs, 2000.

    ERIC Educational Resources Information Center

    Mt. SAC Research Briefs, 2000

    2000-01-01

    These Research Briefs examine Mt. San Antonio College District's (MSAC's) (California) enrollment trends. Over the last few years, the district has drawn a large number of students from surrounding areas; however, there are concerns as to whether this fact will remain the same as new forms of educational techniques such as distance education and…

  15. The Latino Workforce. Statistical Brief.

    ERIC Educational Resources Information Center

    Thomas-Breitfeld, Sean

    This brief analyzes the employment patterns and socioeconomic characteristics of Latinos. Nationally, Hispanics constitute 11.1 percent of the U.S. workforce. The number of Latino workers is expected to grow by 36.3 percent this decade. Working Latinos have persistently had high poverty and unemployment rates due to such factors as insufficient…

  16. Policy Brief: The Four Horsemen

    ERIC Educational Resources Information Center

    Hickrod, G. Alan

    2006-01-01

    In this policy brief, the author contends that there are four other principal causes of the collective poor showing on reaching state equity goals in the United States. These are the Four Horsemen of the Apocalypse in the school finance world. The first horseman rides an economic horse, the second a sociological horse, the third a political horse,…

  17. A brief history of error.

    PubMed

    Murray, Andrew W

    2011-10-01

    The spindle checkpoint monitors chromosome alignment on the mitotic and meiotic spindle. When the checkpoint detects errors, it arrests progress of the cell cycle while it attempts to correct the mistakes. This perspective will present a brief history summarizing what we know about the checkpoint, and a list of questions we must answer before we understand it. PMID:21968991

  18. The Intracellular Domain of Teneurin-1 Induces the Activity of Microphthalmia-associated Transcription Factor (MITF) by Binding to Transcriptional Repressor HINT1

    PubMed Central

    Schöler, Jonas; Ferralli, Jacqueline; Thiry, Stéphane; Chiquet-Ehrismann, Ruth

    2015-01-01

    Teneurins are large type II transmembrane proteins that are necessary for the normal development of the CNS. Although many studies highlight the significance of teneurins, especially during development, there is only limited information known about the molecular mechanisms of function. Previous studies have shown that the N-terminal intracellular domain (ICD) of teneurins can be cleaved at the membrane and subsequently translocates to the nucleus, where it can influence gene transcription. Because teneurin ICDs do not contain any intrinsic DNA binding sequences, interaction partners are required to affect transcription. Here, we identified histidine triad nucleotide binding protein 1 (HINT1) as a human teneurin-1 ICD interaction partner in a yeast two-hybrid screen. This interaction was confirmed in human cells, where HINT1 is known to inhibit the transcription of target genes by directly binding to transcription factors at the promoter. In a whole transcriptome analysis of BS149 glioblastoma cells overexpressing the teneurin-1 ICD, several microphthalmia-associated transcription factor (MITF) target genes were found to be up-regulated. Directly comparing the transcriptomes of MITF versus TEN1-ICD-overexpressing BS149 cells revealed 42 co-regulated genes, including glycoprotein non-metastatic b (GPNMB). Using real-time quantitative PCR to detect endogenous GPNMB expression upon overexpression of MITF and HINT1 as well as promoter reporter assays using GPNMB promoter constructs, we could demonstrate that the teneurin-1 ICD binds HINT1, thus switching on MITF-dependent transcription of GPNMB. PMID:25648896

  19. Helpful Hints for School Emergency Management: The National Incident Management System (NIMS) and Schools. Frequently Asked Questions and FY 2006 NIMS Compliance Activities for Schools

    ERIC Educational Resources Information Center

    US Department of Education, 2006

    2006-01-01

    "Helpful Hints" offers a quick overview of school emergency preparedness topics that are frequently the subject of inquiries. The National Incident Management System (NIMS) is a comprehensive system that improves tribal and local emergency response operations through the use of the Incident Command System (ICS) and the application of standardized…

  20. The intracellular domain of teneurin-1 induces the activity of microphthalmia-associated transcription factor (MITF) by binding to transcriptional repressor HINT1.

    PubMed

    Schöler, Jonas; Ferralli, Jacqueline; Thiry, Stéphane; Chiquet-Ehrismann, Ruth

    2015-03-27

    Teneurins are large type II transmembrane proteins that are necessary for the normal development of the CNS. Although many studies highlight the significance of teneurins, especially during development, there is only limited information known about the molecular mechanisms of function. Previous studies have shown that the N-terminal intracellular domain (ICD) of teneurins can be cleaved at the membrane and subsequently translocates to the nucleus, where it can influence gene transcription. Because teneurin ICDs do not contain any intrinsic DNA binding sequences, interaction partners are required to affect transcription. Here, we identified histidine triad nucleotide binding protein 1 (HINT1) as a human teneurin-1 ICD interaction partner in a yeast two-hybrid screen. This interaction was confirmed in human cells, where HINT1 is known to inhibit the transcription of target genes by directly binding to transcription factors at the promoter. In a whole transcriptome analysis of BS149 glioblastoma cells overexpressing the teneurin-1 ICD, several microphthalmia-associated transcription factor (MITF) target genes were found to be up-regulated. Directly comparing the transcriptomes of MITF versus TEN1-ICD-overexpressing BS149 cells revealed 42 co-regulated genes, including glycoprotein non-metastatic b (GPNMB). Using real-time quantitative PCR to detect endogenous GPNMB expression upon overexpression of MITF and HINT1 as well as promoter reporter assays using GPNMB promoter constructs, we could demonstrate that the teneurin-1 ICD binds HINT1, thus switching on MITF-dependent transcription of GPNMB. PMID:25648896

  1. Hint, Fhit and GalT: Function, Structure, Evolution and Mechanism of Three Branches of the Histidine Triad Superfamily of Nucleotide Hydrolases and Transferases

    PubMed Central

    Brenner, Charles

    2008-01-01

    HIT (histidine triad)1 proteins, named for a motif related to the sequence HφHφHφφ, (φ a hydrophobic amino acid) are a superfamily of nucleotide hydrolases and transferases, which act on the α-phosphate of ribonucleotides, and contain a ∼30 kDa domain that is typically either a homodimer of ∼15 kDa polypeptides with two active-sites or an internally, imperfectly repeated polypeptide that retains a single HIT active site. On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins can be classified into the Hint branch, which consists of adenosine 5′-monophosphoramide hydrolases, the Fhit branch, which consists of diadenosine polyphosphate hydrolases, and the GalT branch, which consists of specific nucleoside monophosphate transferases including galactose-1-phosphate uridylyltransferase, diadenosine tetraphosphate phosphorylase, and adenylylsulfate:phosphate adenylytransferase. At least one human representative of each branch is lost in human diseases. Aprataxin, a Hint branch hydrolase, is mutated in ataxia-oculomotor apraxia syndrome. Fhit is lost early in development of many epithelially derived tumors. GalT is deficient in galactosemia. Additionally, ASW is an avian Hint family member that has evolved to have unusual gene expression properties and the complete loss of its nucleotide binding-site. The potential roles of ASW and Hint in avian sexual development are discussed in an accompanying manuscript. Here we review what is known about biological activities of HIT proteins, the structural and biochemical bases for their functions, and propose a new enzyme mechanism for Hint and Fhit that may account for the differences between HIT hydrolases and transferases. PMID:12119013

  2. 37 CFR 41.68 - Respondent's brief.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., file a respondent brief and serve the brief on all parties in accordance with § 1.903 of this title. (2... (b)(1)(ii) of this section. (x) Certificate of service. A certification that a copy of the respondent... non-compliance and given a non-extendable time period within which to file an amended brief....

  3. 45 CFR 1386.110 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Posthearing briefs. 1386.110 Section 1386.110... Posthearing Procedures, Decisions § 1386.110 Posthearing briefs. The presiding officer must fix the time for filing posthearing briefs. This time may not exceed 30 days after termination of the hearing and...

  4. 16 CFR 1025.22 - Prehearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Prehearing briefs. 1025.22 Section 1025.22... Prehearing briefs. Not later than ten (10) days prior to the hearing, unless otherwise ordered by the Presiding Officer, the parties may simultaneously serve and file prehearing briefs which should set...

  5. 39 CFR 955.10 - Prehearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Prehearing briefs. 955.10 Section 955.10 Postal... CONTRACT APPEALS § 955.10 Prehearing briefs. Link to an amendment published at 76 FR 37660, June 28, 2011... may, in its discretion, require the parties to submit prehearing briefs in any case in which a...

  6. 39 CFR 955.24 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Posthearing briefs. 955.24 Section 955.24 Postal... CONTRACT APPEALS § 955.24 Posthearing briefs. Posthearing briefs may be submitted upon such terms as may be ordered by the Board at the conclusion of the hearing. Ordinarily, they will be simultaneous...

  7. 45 CFR 213.31 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Posthearing briefs. 213.31 Section 213.31 Public..., Decisions § 213.31 Posthearing briefs. The presiding officer shall fix the time for filing posthearings briefs, which may contain proposed findings of fact and conclusions of law, and, if permitted,...

  8. 46 CFR 202.7 - Supplemental briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Supplemental briefs. 202.7 Section 202.7 Shipping... REVIEW BY SECRETARY OF TRANSPORTATION OF ACTIONS BY MARITIME SUBSIDY BOARD § 202.7 Supplemental briefs. If an order taking review is entered by the Secretary, further briefs supplementing the arguments...

  9. 16 CFR 1025.22 - Prehearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Prehearing briefs. 1025.22 Section 1025.22... Prehearing briefs. Not later than ten (10) days prior to the hearing, unless otherwise ordered by the Presiding Officer, the parties may simultaneously serve and file prehearing briefs which should set...

  10. 19 CFR 207.25 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Posthearing briefs. 207.25 Section 207.25 Customs... EXPORTS TO THE UNITED STATES Final Determinations, Short Life Cycle Products § 207.25 Posthearing briefs. Any party may file a posthearing brief concerning the information adduced at or after the hearing...

  11. 39 CFR 955.24 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Posthearing briefs. 955.24 Section 955.24 Postal... CONTRACT APPEALS § 955.24 Posthearing briefs. Posthearing briefs may be submitted upon such terms as may be ordered by the Board at the conclusion of the hearing. Ordinarily, they will be simultaneous...

  12. 5 CFR 2423.33 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Posthearing briefs. 2423.33 Section 2423....33 Posthearing briefs. Except when bench decisions are issued pursuant to § 2423.31(d), posthearing briefs may be filed with the Administrative Law Judge within a time period set by the Judge, not...

  13. 24 CFR 26.48 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Posthearing briefs. 26.48 Section 26.48 Housing and Urban Development Office of the Secretary, Department of Housing and Urban... Posthearing briefs. Posthearing briefs shall be filed only upon order by the ALJ....

  14. 20 CFR 802.215 - Additional briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Additional briefs. 802.215 Section 802.215 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR RULES OF PRACTICE AND PROCEDURE Prereview Procedures Initial Processing § 802.215 Additional briefs. Additional briefs may be filed or ordered in...

  15. 25 CFR 17.9 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Briefs. 17.9 Section 17.9 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROBATE ACTION ON WILLS OF OSAGE INDIANS § 17.9 Briefs. When there are... to file a brief or other statement of his contentions, showing service on opposing counsel...

  16. 37 CFR 41.41 - Reply brief.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Reply brief. 41.41 Section 41... COMMERCE PRACTICE BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES Ex Parte Appeals § 41.41 Reply brief... file a reply brief to an examiner's answer within two months from the date of the examiner's answer....

  17. 19 CFR 207.65 - Prehearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Prehearing briefs. 207.65 Section 207.65 Customs... EXPORTS TO THE UNITED STATES Five-Year Reviews § 207.65 Prehearing briefs. Each party to a five-year review may submit a prehearing brief to the Commission on the date specified in the scheduling notice....

  18. 39 CFR 3001.34 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Briefs. 3001.34 Section 3001.34 Postal Service... § 3001.34 Briefs. (a) When filed. At the close of the taking of testimony in any proceeding, the Commission or the presiding officer shall fix the time for the filing and service of briefs, giving...

  19. 45 CFR 99.31 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Posthearing briefs. 99.31 Section 99.31 Public... CHILD CARE AND DEVELOPMENT FUND Posthearing Procedures, Decisions § 99.31 Posthearing briefs. The presiding officer shall fix the time for filing posthearing briefs, which may contain proposed findings...

  20. 41 CFR 50-203.9 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Briefs. 50-203.9 Section...-Healey Public Contracts Act § 50-203.9 Briefs. (a) Any interested person or organization shall be entitled to file with the administrative law judge, Department of Labor, Washington, D.C., briefs,...

  1. 49 CFR 511.22 - Prehearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Prehearing briefs. 511.22 Section 511.22...; Interlocutory Appeals; Summary Judgment; Settlement § 511.22 Prehearing briefs. Not later ten (10) days prior to... circumstances, simultaneously serve and file prehearing briefs, which shall set forth (a) a statement of...

  2. 46 CFR 202.7 - Supplemental briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Supplemental briefs. 202.7 Section 202.7 Shipping... REVIEW BY SECRETARY OF TRANSPORTATION OF ACTIONS BY MARITIME SUBSIDY BOARD § 202.7 Supplemental briefs. If an order taking review is entered by the Secretary, further briefs supplementing the arguments...

  3. 45 CFR 1386.110 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Posthearing briefs. 1386.110 Section 1386.110... Posthearing Procedures, Decisions § 1386.110 Posthearing briefs. The presiding officer must fix the time for filing posthearing briefs. This time may not exceed 30 days after termination of the hearing and...

  4. 19 CFR 207.65 - Prehearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Prehearing briefs. 207.65 Section 207.65 Customs... EXPORTS TO THE UNITED STATES Five-Year Reviews § 207.65 Prehearing briefs. Each party to a five-year review may submit a prehearing brief to the Commission on the date specified in the scheduling notice....

  5. 36 CFR 1150.71 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Briefs. 1150.71 Section 1150... PRACTICE AND PROCEDURES FOR COMPLIANCE HEARINGS Hearing Procedures § 1150.71 Briefs. The judge may require... also require the parties to submit trial briefs....

  6. 49 CFR 1113.18 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 8 2011-10-01 2011-10-01 false Briefs. 1113.18 Section 1113.18 Transportation... TRANSPORTATION RULES OF PRACTICE ORAL HEARING § 1113.18 Briefs. (a) When filed. In a proceeding which has been the subject of oral hearing, and in which briefs are to be filed, that fact will be stated by...

  7. 37 CFR 41.41 - Reply brief.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Reply brief. 41.41 Section 41... COMMERCE PRACTICE BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES Ex Parte Appeals § 41.41 Reply brief... file a reply brief to an examiner's answer within two months from the date of the examiner's answer....

  8. 42 CFR 430.100 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Posthearing briefs. 430.100 Section 430.100 Public... State Medicaid Plans and Practice to Federal Requirements § 430.100 Posthearing briefs. The presiding officer fixes the time for filing posthearing briefs, which may contain proposed findings of fact...

  9. 45 CFR 213.31 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Posthearing briefs. 213.31 Section 213.31 Public..., Decisions § 213.31 Posthearing briefs. The presiding officer shall fix the time for filing posthearings briefs, which may contain proposed findings of fact and conclusions of law, and, if permitted,...

  10. 42 CFR 430.100 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Posthearing briefs. 430.100 Section 430.100 Public... State Medicaid Plans and Practice to Federal Requirements § 430.100 Posthearing briefs. The presiding officer fixes the time for filing posthearing briefs, which may contain proposed findings of fact...

  11. 5 CFR 2423.33 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Posthearing briefs. 2423.33 Section 2423....33 Posthearing briefs. Except when bench decisions are issued pursuant to § 2423.31(d), posthearing briefs may be filed with the Administrative Law Judge within a time period set by the Judge, not...

  12. 24 CFR 26.48 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Posthearing briefs. 26.48 Section 26.48 Housing and Urban Development Office of the Secretary, Department of Housing and Urban... Posthearing briefs. Posthearing briefs shall be filed only upon order by the ALJ....

  13. 19 CFR 207.25 - Posthearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Posthearing briefs. 207.25 Section 207.25 Customs... EXPORTS TO THE UNITED STATES Final Determinations, Short Life Cycle Products § 207.25 Posthearing briefs. Any party may file a posthearing brief concerning the information adduced at or after the hearing...

  14. 36 CFR 1150.71 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Briefs. 1150.71 Section 1150... PRACTICE AND PROCEDURES FOR COMPLIANCE HEARINGS Hearing Procedures § 1150.71 Briefs. The judge may require... also require the parties to submit trial briefs....

  15. 25 CFR 17.9 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Briefs. 17.9 Section 17.9 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROBATE ACTION ON WILLS OF OSAGE INDIANS § 17.9 Briefs. When there are... to file a brief or other statement of his contentions, showing service on opposing counsel...

  16. 41 CFR 50-203.9 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Briefs. 50-203.9 Section...-Healey Public Contracts Act § 50-203.9 Briefs. (a) Any interested person or organization shall be entitled to file with the administrative law judge, Department of Labor, Washington, D.C., briefs,...

  17. 39 CFR 3001.34 - Briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Briefs. 3001.34 Section 3001.34 Postal Service... § 3001.34 Briefs. (a) When filed. At the close of the taking of testimony in any proceeding, the Commission or the presiding officer shall fix the time for the filing and service of briefs, giving...

  18. 43 CFR 4.110 - Prehearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Prehearing briefs. 4.110 Section 4.110... Prehearing briefs. Based on an examination of the appeal file, the pleadings, and a determination of whether..., in its discretion, require the parties to submit prehearing briefs in any case in which a hearing...

  19. 45 CFR 99.31 - Posthearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Posthearing briefs. 99.31 Section 99.31 Public... CHILD CARE AND DEVELOPMENT FUND Posthearing Procedures, Decisions § 99.31 Posthearing briefs. The presiding officer shall fix the time for filing posthearing briefs, which may contain proposed findings...

  20. 39 CFR 955.10 - Prehearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Prehearing briefs. 955.10 Section 955.10 Postal... CONTRACT APPEALS § 955.10 Prehearing briefs. Based on an examination of the documentation described in... prehearing briefs in any case in which a hearing has been elected pursuant to § 955.9. In the absence of...

  1. 20 CFR 802.215 - Additional briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Additional briefs. 802.215 Section 802.215 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR RULES OF PRACTICE AND PROCEDURE Prereview Procedures Initial Processing § 802.215 Additional briefs. Additional briefs may be filed or ordered in...

  2. 37 CFR 41.67 - Appellant's brief.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Appellant's brief. 41.67... Appellant's brief. (a)(1) Appellant(s) may once, within time limits for filing set forth in § 41.66, file a... title. (2) The brief must be signed by the appellant, or the appellant's duly authorized attorney...

  3. 37 CFR 41.68 - Respondent's brief.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Respondent's brief. 41.68... Respondent's brief. (a)(1) Respondent(s) in an appeal may once, within the time limit for filing set forth in... title. (2) The brief must be signed by the party, or the party's duly authorized attorney or agent,...

  4. 37 CFR 41.37 - Appeal brief.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Appeal brief. 41.37 Section 41.37 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex Parte Appeals § 41.37 Appeal brief. (a) Timing. Appellant must file a brief under...

  5. 17 CFR 9.22 - Appeal brief.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Appeal brief. 9.22 Section 9... Appeals § 9.22 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 9.20 must perfect the appeal by filing an appeal brief with the...

  6. 17 CFR 9.22 - Appeal brief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Appeal brief. 9.22 Section 9... Appeals § 9.22 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 9.20 must perfect the appeal by filing an appeal brief with the...

  7. 17 CFR 9.22 - Appeal brief.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Appeal brief. 9.22 Section 9... Appeals § 9.22 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 9.20 must perfect the appeal by filing an appeal brief with the...

  8. 17 CFR 9.22 - Appeal brief.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Appeal brief. 9.22 Section 9... Appeals § 9.22 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 9.20 must perfect the appeal by filing an appeal brief with the...

  9. 17 CFR 9.22 - Appeal brief.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Appeal brief. 9.22 Section 9... Appeals § 9.22 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 9.20 must perfect the appeal by filing an appeal brief with the...

  10. Brief Counseling with Hispanic American College Students.

    ERIC Educational Resources Information Center

    Littrell, John M.; Cruz, Jeannette

    1998-01-01

    Hispanic-American college students (N=16) met with a Puerto-Rican counselor for two brief counseling sessions. Brief counseling was a viable and effective approach in helping the students reach their goals. Examined types of student concerns about, and student perceptions of, brief counseling. (Author)

  11. STS-93/ Chandra Science Briefing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    This video shows a press briefing, reviewing the type of information which scientist hope to get from the Chandra X-ray Telescope. The telescope is scheduled to be launched during the STS-93 flight. The participants in the briefing are: Don Savage, of NASA Headquarters; Ed Weiler, Associate Administrator for Space Sciences; Alan Bunner, Chandra Project Scientist and Michael Turner, an astrophysicist at the University of Chicago. After the introduction by Mr. Savage, the broad scientific goals of the Chandra mission are reviewed by Dr. Weiler. This is followed by an acknowledgement of many of the people who participated in the development of the Chandra Telescope. This is followed by a discussion of the astrophysics and the information which the telescope should provide. Mrs. Chandrasekhar, the widow of Subrahmanyan Chandrasekhar, was in the audience. She was introduced and spoke briefly about the late Nobel Laureate astrophysicist.

  12. Government Program Briefing: Smart Metering

    SciTech Connect

    Doris, E.; Peterson, K.

    2011-09-01

    This document is adapted and updated from a memo delivered to the City Council of New Orleans, the office of the Mayor of New Orleans, the Chairperson of the Citizen Stakeholders Group (New Orleans Energy Task Force) and the U.S. Department of Energy (DOE) Project Officer in March 2008. This briefing piece provides an overview of the benefits, costs, and challenges of smart metering.

  13. STS-34: Mission Overview Briefing

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Live footage shows Milt Heflin, the Lead Flight Director participating in the STS-34 Mission Briefing. He addresses the primary objective, and answered questions from the audience and other NASA Centers. Heflin also mentions the Shuttle Solar Backscatter Ultraviolet secondary payload, and several experiments. These experiments include Growth Hormone Crystal Distribution (Plants), Polymer Morphology, Sensor Technology Experiment, Mesoscale Lightning Experiment, Shuttle Student Involvement Program "Ice Crystals", and the Air Force Maui Optical Site.

  14. Earnings in e-learning: knowledge, CME credits or both? Hints from analysis of attendance dynamics and users' behaviour.

    PubMed

    Mazzoleni, M Cristina; Rognoni, Carla; Finozzi, Enrico; Landro, Mauro; Capodaglio, Edda; Imbriani, Marcello; Giorgi, Ines

    2010-01-01

    Many papers report and convey positive opinion about the use of e-learning in the healthcare sector. The issue is how to exploit at best such a powerful instrument. Starting from data regarding the usage of a CME e-learning course, attendance dynamics and users' behaviour have been inspected with the aim of getting some hints about how to improve the development and the delivery of e-learning courses for CME, and to promote knowledge acquisition at best. The different paths followed by 7811 users have been modeled, from enrolment to conclusion/drop-out, then the behaviour in terms of effort, elapsed time, achieved result have been analyzed. The obtained results point out: good acceptance (retention rate 83%) of a not basic educational model and effectiveness (success rate 79%). At the same time the inspection of behaviour has shown that there is a good margin of possible improvement in terms of knowledge acquisition. Conclusions provide a list of issues to keep in mind during system development, in order to provide CME e-learning meeting both credit and knowledge acquisition goals. PMID:20841752

  15. NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

    PubMed Central

    Huergo-Zapico, Leticia; Parodi, Monica; Pedrazzi, Marco; Mingari, Maria Cristina; Sparatore, Bianca; Gonzalez, Segundo; Olive, Daniel; Bottino, Cristina

    2016-01-01

    Several evidences suggest that NK cells can patrol the body and eliminate tumors in their initial phases but may hardly control established solid tumors. Multiple factors, including the transition of tumor cells towards a proinvasive/prometastatic phenotype, the immunosuppressive effect of the tumor microenvironment, and the tumor structure complexity, may account for limited NK cell efficacy. Several putative mechanisms of NK cell suppression have been defined in these last years; conversely, the cross talk between NK cells and tumor cells undergoing different transitional phases remains poorly explored. Nevertheless, recent in vitro studies and immunohistochemical analyses on tumor biopsies suggest that NK cells could not only kill tumor cells but also influence their evolution. Indeed, NK cells may induce tumor cells to change the expression of HLA-I, PD-L1, or NKG2D-L and modulate their susceptibility to the immune response. Moreover, NK cells may be preferentially located in the borders of tumor masses, where, indeed, tumor cells can undergo Epithelial-to-Mesenchymal Transition (EMT) acquiring prometastatic phenotype. Finally, the recently highlighted role of HMGB1 both in EMT and in amplifying the recruitment of NK cells provides further hints on a possible effect of NK cells on tumor progression and fosters new studies on this issue. PMID:27294158

  16. Modulation masking release using the Brazilian-Portuguese HINT: Psychometric functions and the effect of speech time compression

    PubMed Central

    Grose, John H.; Griz, Silvana; Pacífico, Fernando A.; Advíncula, Karina P.; Menezes, Denise C.

    2015-01-01

    Objective The Brazilian-Portuguese Hearing In Noise Test (HINT) was used to investigate the benefit to speech recognition of listening in a fluctuating background. The goal was to determine whether modulation masking release varied as a function of the speech-to-masker ratio at threshold. Speech-to-masker ratio at threshold was manipulated using the novel approach of adjusting the time-compression of the speech. Design Experiment 1 measured performance-intensity functions in both a steady speech-shaped noise masker and a 10-Hz square-wave modulated masker. Experiment 2 measured speech-to-masker ratios at threshold as a function of time-compression of the speech (0, 33, and 50%) in both maskers. Study Sample Participants were normal-hearing adults who were native speakers of Brazilian Portuguese (Experiment 1: N = 10; Experiment 2: N = 30). Results The slope of the performance-intensity function was shallower in the modulated masker than in the steady masker for both words and sentences. Thresholds increased with increasing time-compression in both maskers, but more markedly in the modulated masker, resulting in reduced modulation masking release with increasing time-compression. Conclusions Speech-to-masker ratio at threshold varies with time-compression of speech. The results are relevant to the issue of whether degree of masker modulation benefit depends on speech-to-masker ratio at threshold. PMID:25630394

  17. Evolution of hedgehog and hedgehog-related genes, their origin from Hog proteins in ancestral eukaryotes and discovery of a novel Hint motif

    PubMed Central

    Bürglin, Thomas R

    2008-01-01

    Background The Hedgehog (Hh) signaling pathway plays important roles in human and animal development as well as in carcinogenesis. Hh molecules have been found in both protostomes and deuterostomes, but curiously the nematode Caenorhabditis elegans lacks a bona-fide Hh. Instead a series of Hh-related proteins are found, which share the Hint/Hog domain with Hh, but have distinct N-termini. Results We performed extensive genome searches such as the cnidarian Nematostella vectensis and several nematodes to gain further insights into Hh evolution. We found six genes in N. vectensis with a relationship to Hh: two Hh genes, one gene with a Hh N-terminal domain fused to a Willebrand factor type A domain (VWA), and three genes containing Hint/Hog domains with distinct novel N-termini. In the nematode Brugia malayi we find the same types of hh-related genes as in C. elegans. In the more distantly related Enoplea nematodes Xiphinema and Trichinella spiralis we find a bona-fide Hh. In addition, T. spiralis also has a quahog gene like C. elegans, and there are several additional hh-related genes, some of which have secreted N-terminal domains of only 15 to 25 residues. Examination of other Hh pathway components revealed that T. spiralis - like C. elegans - lacks some of these components. Extending our search to all eukaryotes, we recovered genes containing a Hog domain similar to Hh from many different groups of protists. In addition, we identified a novel Hint gene family present in many eukaryote groups that encodes a VWA domain fused to a distinct Hint domain we call Vint. Further members of a poorly characterized Hint family were also retrieved from bacteria. Conclusion In Cnidaria and nematodes the evolution of hh genes occurred in parallel to the evolution of other genes that contain a Hog domain but have different N-termini. The fact that Hog genes comprising a secreted N-terminus and a Hog domain are found in many protists indicates that this gene family must have

  18. Overcoming students' misconceptions concerning thermal physics with the aid of hints and peer interaction during a lecture course

    NASA Astrophysics Data System (ADS)

    Leinonen, Risto; Asikainen, Mervi A.; Hirvonen, Pekka E.

    2013-12-01

    As has been shown by previous research, students may possess various misconceptions in the area of thermal physics. In order to help them overcome misconceptions observed prior to instruction, we implemented a one-hour lecture-based intervention in their introductory thermal physics course. The intervention was held after the conventional lectures and homework sessions, and it consisted of three phases: individual working, hinting, and peer discussion. To probe students’ conceptual understanding before, during, and after the intervention, use was made of a diagnostic test related to the multiphased process of an ideal gas [D. E. Meltzer, Am. J. Phys. 72, 1432 (2004)AJPIAS0002-950510.1119/1.1789161]. The students’ conceptions were monitored by analyzing the explanations they provided and by recording the peer discussions of five voluntary pairs. The intervention helped students to realize the flaws in their explanations and increased the proportion of their scientific explanations, the increase being statistically significant in five tasks out of seven. When the same themes were addressed in a post-test, it was shown that the level of accurate explanations remained almost constant after the intervention, and hence it could be deduced that the impact had not been short-lived. In comparison with earlier studies conducted with the same material, our intervention produced a better learning outcome, the difference being 15-20 percentage points. In addition, the number of misconceptions on the part of the students was smaller in our study, although with individual exceptions. Hence, we conclude that the intervention was successful and that similar interventions could also be designed and implemented in other areas of physics.

  19. Perturbed Lepton-Specific Two-Higgs-Doublet Model Facing Experimental Hints for Physics beyond the Standard Model.

    PubMed

    Crivellin, Andreas; Heeck, Julian; Stoffer, Peter

    2016-02-26

    BABAR, Belle, and LHCb Collaborations report evidence for new physics in B→Dτν and B→D^{*}τν of approximately 3.8σ. There is also the long lasting discrepancy of about 3σ in the anomalous magnetic moment of the muon, and the branching ratio for τ→μνν is 1.8σ (2.4σ) above the standard model expectation using the HFAG (PDG) values. Furthermore, CMS Collaboration finds hints for a nonzero decay rate of h→μτ. Interestingly, all these observations can be explained by introducing new scalars. In this Letter we consider these processes within a lepton-specific two-Higgs doublet model (i.e., of type X) with additional nonstandard Yukawa couplings. It is found that one can accommodate τ→μνν with modified Higgs-τ couplings. The anomalous magnetic moment of the muon can be explained if the additional neutral CP-even Higgs boson H is light (below 100 GeV). Also R(D) and R(D^{*}) can be easily explained by additional t-c-Higgs couplings. Combining these t-c couplings with a light H the decay rate for t→Hc can be in a testable range for the LHC. Effects in h→μτ are also possible, but in this case a simultaneous explanation of the anomalous magnetic moment of the muon is difficult due to the unavoidable τ→μγ decay. PMID:26967409

  20. Perturbed Lepton-Specific Two-Higgs-Doublet Model Facing Experimental Hints for Physics beyond the Standard Model

    NASA Astrophysics Data System (ADS)

    Crivellin, Andreas; Heeck, Julian; Stoffer, Peter

    2016-02-01

    BABAR, Belle, and LHCb Collaborations report evidence for new physics in B →D τ ν and B →D*τ ν of approximately 3.8 σ . There is also the long lasting discrepancy of about 3 σ in the anomalous magnetic moment of the muon, and the branching ratio for τ →μ ν ν is 1.8 σ (2.4 σ ) above the standard model expectation using the HFAG (PDG) values. Furthermore, CMS Collaboration finds hints for a nonzero decay rate of h →μ τ . Interestingly, all these observations can be explained by introducing new scalars. In this Letter we consider these processes within a lepton-specific two-Higgs doublet model (i.e., of type X) with additional nonstandard Yukawa couplings. It is found that one can accommodate τ →μ ν ν with modified Higgs-τ couplings. The anomalous magnetic moment of the muon can be explained if the additional neutral C P -even Higgs boson H is light (below 100 GeV). Also R (D ) and R (D*) can be easily explained by additional t -c -Higgs couplings. Combining these t -c couplings with a light H the decay rate for t →H c can be in a testable range for the LHC. Effects in h →μ τ are also possible, but in this case a simultaneous explanation of the anomalous magnetic moment of the muon is difficult due to the unavoidable τ →μ γ decay.

  1. Could structural similarity of specific domains between animal globins and plant antenna proteins provide hints important for the photoprotection mechanism?

    PubMed

    Ioannidis, Nikolaos E; Kotzabasis, Kiriakos

    2015-01-01

    Non photochemical quenching is a fundamental mechanism in photosynthesis, which protects plants against excess excitation energy and is of crucial importance for their survival and fitness. In the last decades hundreds of papers have appeared that describe the role of antenna regulation in protection or the so called qE response. However, the exact quenching site is still obscure. Previously overlooked features of the antenna may provide hints towards the elucidation of its functionality and of the quenching mechanism. Recently it was demonstrated that the catalytic domain of human myoglobin that binds the pigment (i.e. heme) is similar in structure to the domain of the light harvesting complex II of pea that binds Chl a 614 (former known as b3). In addition, it is well accepted that conformational changes of the chlorophyll macrocycle result in reversible changes of fluorescence (the lowest fluorescence corresponds to non planar macrocycle). Here we put forward a hypothesis regarding the molecular mechanism that leads to the formation of a quenching center inside the antenna proteins. Our main suggestion is that a conformational change of helix H5 (known also as helix D) forces conformational changes in the macrocycle of Chl a 614 is implicated in the ΔA535 absorbance change and quenching during photoprotective qE. The specific features (some of them similar to those of heme domain of globins) of the b3 domain account for these traits. The model predicts that antenna proteins having b3 pigments (i.e. LHCII, CP29, CP26) can act as potential quenchers. PMID:25218499

  2. Enhanced models for stellar Doppler noise reveal hints of a 13-year activity cycle of 55 Cancri

    NASA Astrophysics Data System (ADS)

    Baluev, Roman V.

    2015-01-01

    We consider the impact of Doppler noise models on the statistical robustness of the exoplanetary radial velocity fits. We show that the traditional model of the Doppler noise with an additive jitter can generate large non-linearity effects, decreasing the reliability of the fit, especially in the cases when a correlated Doppler noise is involved. We introduce a regularization of the additive noise model that can gracefully eliminate its singularities together with the associated non-linearity effects. We apply this approach to Doppler time series data of several exoplanetary systems. It demonstrates that our new regularized noise model yields orbital fits that have either increased or at least the same statistical robustness, in comparison with the simple additive jitter. Various statistical uncertainties in the parametric estimations are often reduced, while planet detection significance is often increased. Concerning the 55 Cnc five-planet system, we show that its Doppler data contain significant correlated (`red') noise. Its correlation time-scale is in the range from days to months, and its magnitude is much larger than the effect of the planetary N-body perturbations in the radial velocity (these perturbations thus appear undetectable). Characteristics of the red noise depend on the spectrograph/observatory, and also show a cyclic time variation in phase with the public Ca II H&K and photometry measurements. We interpret this modulation as a hint of the long-term activity cycle of 55 Cnc, similar to the solar 11-yr cycle. We estimate the 55 Cnc activity period by 12.6± ^{2.5}_{1.0} yr, with the nearest minimum presumably expected in 2014 or 2015.

  3. Healthy household hints.

    PubMed

    Taylor, P

    1999-01-01

    Ten commonly found items that can help keep your home clean are listed. Baking soda and vinegar are effective in cleaning drains. Certain plants, including English ivy and the spider plant, filter carbon dioxide and carbon monoxide out of the air. In addition, specific brand-name products, such as Bon Ami and "Simple Green", are also good alternative cleansers. Contact information is provided. PMID:11366863

  4. Hints on Sharing Books.

    ERIC Educational Resources Information Center

    Dorsey, Mary E., Comp.; Horne, Ulysses G., Comp.

    Based on the realization that each child must be given the opportunity to develop as a unique individual and that exposure to books expands a child's world, stimulating his creative thinking and his desire for new experiences, this booklet presents in outline form a variety of suggestions for encouraging children to share the books they have read.…

  5. Magnesium metabolism: a brief review.

    PubMed Central

    Paymaster, N. J.

    1976-01-01

    The important role played by the magnesium ion in the body is not generally recognized. The action of numerous enzyme systems critical to cellular metabolism is regulated by it and it contributes importantly to macromolecular structure. Magnesium defiency occurs more often than is generally suspected; magnesium excess, though uncommon, is of special interest to the anaesthetist because it produces a curare-like effect on neuromuscular transmission. It is hoped that this brief review of magnesium metabolism will draw attention to its importance and relevance in everyday practice. PMID:942168

  6. Infantile Hemangioma: A Brief Review

    PubMed Central

    BOTA, MADALINA; POPA, GHEORGHE; BLAG, CRISTINA; TATARU, ALEXANDRU

    2015-01-01

    Infantile hemangiomas as frequent infancy tumors have been a controversial issue of medical scientists worldwide. Their clinical aspects are various and their physiopathology is yet to be fully understood. Numerous publications outline the characteristics, causes, evolution possibilities and therapeutic approaches. Deciding whether to treat or not is the main question of this kind of pathology. Hemangiomas that have complications or can cause irreversible damage need therapy. This is a brief review of up-to-date information regarding the presentation of infantile hemangiomas and target-therapies. PMID:26528043

  7. Quantitative Analysis of BTF3, HINT1, NDRG1 and ODC1 Protein Over-Expression in Human Prostate Cancer Tissue

    PubMed Central

    Symes, Andrew J.; Eilertsen, Marte; Millar, Michael; Nariculam, Joseph; Freeman, Alex; Notara, Maria; Feneley, Mark R.; Patel, Hitenedra R. H.; Masters, John R. W.; Ahmed, Aamir

    2013-01-01

    Prostate carcinoma is the most common cancer in men with few, quantifiable, biomarkers. Prostate cancer biomarker discovery has been hampered due to subjective analysis of protein expression in tissue sections. An unbiased, quantitative immunohistochemical approach provided here, for the diagnosis and stratification of prostate cancer could overcome this problem. Antibodies against four proteins BTF3, HINT1, NDRG1 and ODC1 were used in a prostate tissue array (> 500 individual tissue cores from 82 patients, 41 case pairs matched with one patient in each pair had biochemical recurrence). Protein expression, quantified in an unbiased manner using an automated analysis protocol in ImageJ software, was increased in malignant vs non-malignant prostate (by 2-2.5 fold, p<0.0001). Operating characteristics indicate sensitivity in the range of 0.68 to 0.74; combination of markers in a logistic regression model demonstrates further improvement in diagnostic power. Triple-labeled immunofluorescence (BTF3, HINT1 and NDRG1) in tissue array showed a significant (p<0.02) change in co-localization coefficients for BTF3 and NDRG1 co-expression in biochemical relapse vs non-relapse cancer epithelium. BTF3, HINT1, NDRG1 and ODC1 could be developed as epithelial specific biomarkers for tissue based diagnosis and stratification of prostate cancer. PMID:24386364

  8. Using the Internet to Help With Diet, Weight, and Physical Activity: Results From the Health Information National Trends Survey (HINTS)

    PubMed Central

    McCully, Scout N; Don, Brian P

    2013-01-01

    Background The Internet offers a viable platform for cost-effective and wide-reaching health interventions. However, little is known about use of the Internet to help with diet, weight, and physical activity (DWPA) using a nationally representative sample from the United States. Objective To (1) assess the demographic characteristics of people who use the Internet to help with DWPA, (2) assess whether usage trends changed over time, and (3) investigate the associations between using the Internet for DWPA and health behaviors. Methods Data on Internet users from the 2007 and 2011 iterations of the Health Information National Trends Survey (HINTS), N=4827 were analyzed using multiple logistic regression to determine the demographic correlates of using the Internet for help with DWPA. Multiple linear regression was used to test the associations between Internet use for DWPA and three health behaviors: fruit intake, vegetable intake, and physical activity. Results A larger percentage of Internet users used the Internet for DWPA in 2011 (42.83%) than in 2007 (40.43%). In general, Internet users who were younger (OR 0.98, P<.001), more educated (OR 1.40, P<.001), married (OR 1.06, P=.03), of a minority race (non-Hispanic blacks: OR 1.14, P=.02; Hispanics: OR 1.42, P=.01), and who had a higher Body Mass Index (BMI) (OR 1.04, P<.001) were more likely to use the Internet for DWPA. Across survey years, gender was not associated with using the Internet for DWPA (OR 1.03, P=.12), but there was a significant interaction between survey year and gender (OR 1.95, P=.002); in 2007, men were more likely to use the Internet for DWPA, but women were more likely to do so in 2011. Using the Internet for DWPA was associated with more vegetable intake (B=.22, P=.002), more fruit intake (B=.19, P=.001), and more moderate exercise (B=.25, P=.001), although the strength of the associations between using the Internet for DWPA and fruit intake and exercise was weaker in 2011 than in 2007

  9. TEAC Exercise Workbook: Writing the "Inquiry Brief" and "Inquiry Brief Proposal"

    ERIC Educational Resources Information Center

    Teacher Education Accreditation Council, 2010

    2010-01-01

    This workbook is about producing the "Inquiry Brief" or "Inquiry Brief Proposal" for TEAC (Teacher Education Accreditation Council) accreditation. It is designed as a companion to the TEAC "Guide to Accreditation." The exercises in this workbook are selected by the writing workshop presenters to help program faculty get started on their "Brief."…

  10. Elective brief psychotherapy with children.

    PubMed

    Turecki, S

    1982-10-01

    There does not as yet exist a clearly unifying concept of brief psychotherapy with children. Various forms of shortened treatment have been reported as successful. The technique described in this paper is a form of individual therapy based on psychoanalytic principles, especially those of ego psychology. It is primarily recommended for children who have suffered a real of symbolic object loss. Distinctive features include the early definition of a focus, a predetermined time limit, and careful attention to termination issues. The goals are relatively ambitious. When successful the therapy results in persistent psychodynamic changes. Case examples are used to illustrate how these positive results may occur through the medium of identification with the therapist, which permits a resolution or lessening of ambivalent dependence. This in turn allows the treatment experience to act as a model for future relationships with limited givers. PMID:7158671

  11. STS-114: Discovery Impromptu Briefing

    NASA Technical Reports Server (NTRS)

    2005-01-01

    Dr. Griffin, NASA Administrator, is accompanied by members of The U.S. House of Representatives in this STS-114 Discovery Impromptu briefing. The U.S. House of Representatives present include: Sherwood Boehlert, House Science Committee Chairman, Senator Hutchinson, Sheila Jackson, 18th Congressional District Texas, Al Green, 9th Congressional District, Representative Jim Davis, Florida, and Gene Green, 29th District, Texas. Griffin talks about the problem that occurred with the external fuel tank sensor of the Space Shuttle Discovery and the effort NASA is pursuing to track the problem, and identify the root cause. He answers questions from the news media about the next steps for the Space Shuttle Discovery, time frame for the launch, and activities for the astronauts for the next few days.

  12. XTE Science Briefing from KSCNF

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The X-ray Timing Explorer (XTE), launched on Dec. 30, 1995, is a Satellite that observes the fast-moving, high-energy worlds of black holes, neutron stars, x-ray pulsars and bursts of X-rays that light up the sky and then disappear forever. This videotape presents a pre-launch science briefing to the press by a few of the scientist and managers associated with the XTE satellite. The moderator for the press briefing is Jim Sahli, from the Public Affairs Office at Goddard Space Flight Center (GSFC). He introduces Alan Bunner, of the High Energy Astrophysics at NASA Headquarters; Fred Lamb, from the University of Illinois; Richard Mashotzky, X Ray Scientist at GSFC; Rick Rothschild, Principal Investigator from the University of California at San Diego; and Dale Schultz, the XTE project manager at GSFC. Dr. Bunner explains the electromagnetic spectrum, the placement of x-rays and the importance of the XTE observations to a better understanding of the Universe. Dr. Lamb, explains the difference between white dwarfs, neutron stars and black holes, and the type of observations that the XTE will give to a further understanding of these phenomena. Dr. Mashotzky expands the viewpoint to beyond the galaxy, and explains the interests of scientists who hope to use XTE to further study Quasars and Active Galactic Nuclei. Dr. Rothschild reviews some of the features of XTE, using a diagram to show the features of interest, such as the X ray Telescopes, and the collecting Proportional Counter Array (PCA.) Mr. Schultz presents a videotape tour of the XTE, in which he shows the scientific instruments and the other features of the satellite. In this tour, the source of each of the instruments is noted. Questions from the members of the press are then fielded. Many of the questions are about the cost of the XTE and any problems that are anticipated in regards to the launch.

  13. Delta WIND Mission Science Briefing

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The science objectives of the WIND mission are to: 1) provide complete plasma, energetic particle, and magnetic field input for magnetospheric and ionospheric studies; 2) Determine the magnetospheric output to interplanetary space in the up-stream region; 3) Investigate basic plasma processes occurring in the near-Earth solar wind; and 4) Provide baseline ecliptic plane observations to be used in heliospheric latitudes from ULYSSES. The WIND science briefing is presented by George Diller, NASA public affairs; Dr. Robert L. Carovillano, Project Scientist for the Global Geospace Science Initiative, NASA Headquarters; Dr. Mario H. Acuna, Project Scientist for the WIND Project, Goddard Space Flight Center (GSFC); Dr. Keith W. Ogilvie, Principle Investigator, Solar Wind Experiment at GSFC; Dr. Jean Louis Bougeret, Principle Investigator, Radio/Plasma Wave Experiment, Paris; and Dr. Eugeny Mazets, Co-Principle Investigator, Russian Gamma Ray Spectrometer Instrument, St. Pertersburg, Russia. Dr. Carovillano presents a cartoon slide of the Solar Terrestrial System and describes the Sun and the Magnetic field of the Earth. Dr. Acuna also presents a cartoon slide describing GEOTAIL, POLAR, WIND, SOHO, ULYSSES and Cluster which are the various tools used to study the complex solar terrestrial system. Dr. Ogilvie explains four particle and wave instruments on WIND. These instruments will be used to study the contributions and characteristics of plasma and plasma waves that occur in the solar wind. Dr. Bougeret explains the European participation in the WIND mission. He also shows a slide presentation of SOHO and the CLUSTER spacecraft. Dr. Mazets explains the main objective of the Transient Gamma Ray Spectrometer (TGRS) aboard the WIND spacecraft, which is to perform high resolution measurements of Gamma Ray Burst spectra and time histories, with emphasis on the search for line features in the energy spectra. The briefing ends with a question and answer period. See NONP

  14. 37 CFR 41.66 - Time for filing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Time for filing briefs. 41.66... for filing briefs. (a) An appellant's brief must be filed no later than two months from the latest.... The time for filing an appellant's brief or an amended appellant's brief may not be extended. (b)...

  15. 37 CFR 41.66 - Time for filing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Time for filing briefs. 41.66... for filing briefs. (a) An appellant's brief must be filed no later than two months from the latest.... The time for filing an appellant's brief or an amended appellant's brief may not be extended. (b)...

  16. 29 CFR 2200.93 - Briefs before the Commission.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Briefs before the Commission. 2200.93 Section 2200.93 Labor... Posthearing Procedures § 2200.93 Briefs before the Commission. (a) Requests for briefs. The Commission ordinarily will request the parties to file briefs on issues before the Commission. After briefs...

  17. 29 CFR 2200.93 - Briefs before the Commission.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Briefs before the Commission. 2200.93 Section 2200.93 Labor... Posthearing Procedures § 2200.93 Briefs before the Commission. (a) Requests for briefs. The Commission ordinarily will request the parties to file briefs on issues before the Commission. After briefs...

  18. 28 CFR 71.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....36 Post-hearing briefs. ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not to exceed 60... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Post-hearing briefs. 71.36 Section...

  19. 28 CFR 71.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....36 Post-hearing briefs. ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not to exceed 60... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Post-hearing briefs. 71.36 Section...

  20. 15 CFR 25.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not to... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Post-hearing briefs. 25.36 Section...

  1. Kaufman Brief Intelligence Test (K-BIT).

    ERIC Educational Resources Information Center

    Smith, Douglas K.

    1999-01-01

    This article describes the Kaufman Brief Intelligence Test, an assessment of intelligence for individuals ages 4 to 90. The test is designed for those circumstances in which a brief measure of intelligence will suffice and trained professionals may be unavailable for the assessments. Its administration, reliability, and validity are discussed.…

  2. UNESCO Policy Briefs on Early Childhood, 2002.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Early Childhood and Family Education Unit.

    This document consists of eight double-sided briefs addressing aspects of the field of early childhood education. Titles of the briefs are as follows: (1) "Early Childhood Care? Development? Education?," outlining the distinctions between these terms; (2) "Planning for Access: Develop a Data System First," highlighting Brazil's census to collect…

  3. Internship or Indenture? Research Brief. Edition 2

    ERIC Educational Resources Information Center

    Sutton Trust, 2014

    2014-01-01

    This brief analyzes the latest higher education data and government wage statistics to examine the number of unpaid graduate interns in the United Kingdom and the cost to an individual of doing an unpaid internship. It also includes newly published Ipsos Mori polling on attitudes to unpaid internships. Key findings in this brief include: (1) 31%…

  4. 50 CFR 37.33 - Environmental briefing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 9 2014-10-01 2014-10-01 false Environmental briefing. 37.33 Section 37..., ARCTIC NATIONAL WILDLIFE REFUGE, ALASKA Environmental Protection § 37.33 Environmental briefing. The permittee shall provide opportunities for the Regional Director to conduct environmental and other...

  5. 50 CFR 37.33 - Environmental briefing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false Environmental briefing. 37.33 Section 37..., ARCTIC NATIONAL WILDLIFE REFUGE, ALASKA Environmental Protection § 37.33 Environmental briefing. The permittee shall provide opportunities for the Regional Director to conduct environmental and other...

  6. 50 CFR 37.33 - Environmental briefing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false Environmental briefing. 37.33 Section 37..., ARCTIC NATIONAL WILDLIFE REFUGE, ALASKA Environmental Protection § 37.33 Environmental briefing. The permittee shall provide opportunities for the Regional Director to conduct environmental and other...

  7. 37 CFR 41.67 - Appellant's brief.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... (a)(1) Appellant(s) may once, within time limits for filing set forth in § 41.66, file a brief and... upon failure of that appellant to file an appellant's brief, accompanied by the requisite fee, within.... (x) Related proceedings appendix. An appendix containing copies of decisions rendered by a court...

  8. 19 CFR 207.23 - Prehearing brief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Prehearing brief. 207.23 Section 207.23 Customs... EXPORTS TO THE UNITED STATES Final Determinations, Short Life Cycle Products § 207.23 Prehearing brief... days prior to the date of the hearing specified in the notice of scheduling, a prehearing...

  9. 19 CFR 207.23 - Prehearing brief.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Prehearing brief. 207.23 Section 207.23 Customs... EXPORTS TO THE UNITED STATES Final Determinations, Short Life Cycle Products § 207.23 Prehearing brief... days prior to the date of the hearing specified in the notice of scheduling, a prehearing...

  10. 14 CFR 136.7 - Passenger briefings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Passenger briefings. 136.7 Section 136.7... PARKS AIR TOUR MANAGEMENT National Air Tour Safety Standards § 136.7 Passenger briefings. (a) Before... opening exits and exiting the aircraft. (b) For flight segments over water beyond the shoreline,...

  11. Microgravity: Fall into Mathematics. Educational Brief.

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration, Washington, DC.

    Each year the National Aeronautics and Space Administration (NASA) produces new educational products that are used by NASA educational staff at NASA-sponsored workshops and events. Part of the series, "The Great Minds of Microgravity", Galileo, Newton, and Einstein, are the subjects of this brief. The materials include a brief introduction to each…

  12. The GO4KIDDS Brief Adaptive Scale

    ERIC Educational Resources Information Center

    Perry, Adrienne; Taheri, Azin; Ting, Victoria; Weiss, Jonathan

    2015-01-01

    Background: Accurate measurement of adaptive behaviour is important in both clinical and research contexts. While several good clinical measures exist, as well as brief research measures for adults with intellectual disability, there is need for a brief and efficient measure for research with children and youth. We present preliminary psychometric…

  13. 17 CFR 171.25 - Appeal brief.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Appeal brief. 171.25 Section... Denial and Registration Actions § 171.25 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 171.23, shall perfect the appeal by filing...

  14. 17 CFR 171.25 - Appeal brief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Appeal brief. 171.25 Section... Denial and Registration Actions § 171.25 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 171.23, shall perfect the appeal by filing...

  15. 17 CFR 171.25 - Appeal brief.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Appeal brief. 171.25 Section... Denial and Registration Actions § 171.25 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 171.23, shall perfect the appeal by filing...

  16. 17 CFR 171.25 - Appeal brief.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Appeal brief. 171.25 Section... Denial and Registration Actions § 171.25 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 171.23, shall perfect the appeal by filing...

  17. 37 CFR 41.37 - Appeal brief.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... purely legal in nature, when responding to a point made in the examiner's rejection, the appeal brief... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Appeal brief. 41.37 Section... COMMERCE PRACTICE BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES Ex Parte Appeals § 41.37...

  18. 17 CFR 171.25 - Appeal brief.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Appeal brief. 171.25 Section..., Membership Denial and Registration Actions § 171.25 Appeal brief. (a) Time to file. Any person who has filed a notice of appeal in accordance with the provisions of § 171.23, shall perfect the appeal by...

  19. 49 CFR 1113.18 - Briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Briefs. 1113.18 Section 1113.18 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE ORAL HEARING § 1113.18 Briefs. (a) When filed. In a proceeding which has been the subject of oral hearing, and in...

  20. 50 CFR 37.33 - Environmental briefing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Environmental briefing. 37.33 Section 37..., ARCTIC NATIONAL WILDLIFE REFUGE, ALASKA Environmental Protection § 37.33 Environmental briefing. The permittee shall provide opportunities for the Regional Director to conduct environmental and other...

  1. 50 CFR 37.33 - Environmental briefing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false Environmental briefing. 37.33 Section 37..., ARCTIC NATIONAL WILDLIFE REFUGE, ALASKA Environmental Protection § 37.33 Environmental briefing. The permittee shall provide opportunities for the Regional Director to conduct environmental and other...

  2. 14 CFR 91.519 - Passenger briefing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... briefed on— (1) Smoking. Each passenger shall be briefed on when, where, and under what conditions smoking... Regulations require passenger compliance with lighted passenger information signs and no smoking placards, prohibit smoking in lavatories, and require compliance with crewmember instructions with regard to...

  3. Brief Psychotherapy Methods in Clinical Research.

    ERIC Educational Resources Information Center

    Koss, Mary P.; And Others

    1986-01-01

    After a concise overview of the technical characteristics that define brief psychotherapy, the current use and misuse of these methods in clinical research on the outcome and process of treatment is examined. Suggests that brief psychotherapy methods possess unique technical advantages to the researcher. (Author/BL)

  4. 14 CFR 91.519 - Passenger briefing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... briefed on— (1) Smoking. Each passenger shall be briefed on when, where, and under what conditions smoking... Regulations require passenger compliance with lighted passenger information signs and no smoking placards, prohibit smoking in lavatories, and require compliance with crewmember instructions with regard to...

  5. 14 CFR 91.519 - Passenger briefing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... briefed on— (1) Smoking. Each passenger shall be briefed on when, where, and under what conditions smoking... Regulations require passenger compliance with lighted passenger information signs and no smoking placards, prohibit smoking in lavatories, and require compliance with crewmember instructions with regard to...

  6. 14 CFR 91.519 - Passenger briefing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... briefed on— (1) Smoking. Each passenger shall be briefed on when, where, and under what conditions smoking... Regulations require passenger compliance with lighted passenger information signs and no smoking placards, prohibit smoking in lavatories, and require compliance with crewmember instructions with regard to...

  7. School Culture: "The Hidden Curriculum." Issue Brief

    ERIC Educational Resources Information Center

    Jerald, Craig D.

    2006-01-01

    This is the sixth in a series of issue briefs to be written for The Center for Comprehensive School Reform and Improvement during 2006. The impact of organizational culture on student achievement is discussed in this issue brief. Gaining a deep understanding of what a strong, positive organizational culture looks like and how it works can help…

  8. 76 FR 50715 - Briefing on Partner Vetting System Pilot Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ...; ] DEPARTMENT OF STATE Agency for International Development Briefing on Partner Vetting System Pilot Program... briefing. SUMMARY: Notice is hereby given of a briefing on the Partner Vetting System (PVS) pilot...

  9. 6 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ will fix the time for filing such briefs. Such briefs... 6 Domestic Security 1 2013-01-01 2013-01-01 false Post-hearing briefs. 13.36 Section...

  10. NASA Tech Briefs, February 2009

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Tech Briefs are short announcements of innovations originating from research and development activities of the National Aeronautics and Space Administration. They emphasize information considered likely to be transferable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. Topics covered include: Measuring Low Concentrations of Liquid Water in Soil; The Mars Science Laboratory Touchdown Test Facility; Non-Contact Measurement of Density and Thickness Variation in Dielectric Materials; Compact Microwave Fourier Spectrum Analyzer; InP Heterojunction Bipolar Transistor Amplifiers to 255 GHz; Combinatorial Generation of Test Suites; In-Phase Power-Combined Frequency Tripler at 300 GHz; Electronic System for Preventing Airport Runway Incursions; Smaller but Fully Functional Backshell for Cable Connector; Glove-Box or Desktop Virtual-Reality System; Composite Layer Manufacturing with Fewer Interruptions; Improved Photoresist Coating for Making CNT Field Emitters; A Simplified Diagnostic Method for Elastomer Bond Durability; Complex Multifunctional Polymer/Carbon-Nanotube Composites; Very High Output Thermoelectric Devices Based on ITO Nanocomposites; Reducing Unsteady Loads on a Piggyback Miniature Submarine; Ultrasonic/Sonic Anchor; Grooved Fuel Rings for Nuclear Thermal Rocket Engines; Pulsed Operation of an Ion Accelerator; Autonomous Instrument Placement for Mars Exploration Rovers; Mission and Assets Database; TCP/IP Interface for the Satellite Orbit Analysis Program (SOAP); Trajectory Calculator for Finite-Radius Cutter on a Lathe; Integrated System Health Management Development Toolkit.

  11. Mars Observer Orbit Insertion Briefing

    NASA Technical Reports Server (NTRS)

    1993-01-01

    For the first part of this briefing, see NONP-NASA-VT-2000081556. Marvin Traxler continues his discussion on signal tracking from the Mars Observer. Julie Webster, Lead Engineer, Telecommunications Subsystem, is introduced. She explains how signals coming back from Mars are detected. Dr. Pasquale Esposito talks about flyby orbits and capture orbits. He says that frequencies coming from the spacecraft can determine if the spacecraft has flown by Mars, or if a capture orbit has occurred. Charles Whetsel, System Engineer Spacecraft Team, presents a computer program. He shows where the signal will appear on the computer from the Spacecraft. Suzanne Dodd presents orbit insertion geometry. Dr. Arden Albee, Project Scientist Mars Observer Project, Cal Tech tech, says that Mars is studied to get more data to confirm their hypotheses derived from previous Mars Missions such as the Viking Mars Program and the Mariner Program. Dr. Albee also describes instrumentation on the Mars Observer such as the Ultra Stable Oscillator, Mars Orbiter Laser Altimeter, and Magnetometer. The camera on the spacecraft is similar to a fax machine because it scans one line at a time as the spacecraft orbits Mars. Dr. Michael Malin, Principle Investigator Mars Observer Camera, Malin Space Science Systems, Inc., describe this process.

  12. Engineering Technical Review Planning Briefing

    NASA Technical Reports Server (NTRS)

    Gardner, Terrie

    2012-01-01

    The general topics covered in the engineering technical planning briefing are 1) overviews of NASA, Marshall Space Flight Center (MSFC), and Engineering, 2) the NASA Systems Engineering(SE) Engine and its implementation , 3) the NASA Project Life Cycle, 4) MSFC Technical Management Branch Services in relation to the SE Engine and the Project Life Cycle , 5) Technical Reviews, 6) NASA Human Factor Design Guidance , and 7) the MSFC Human Factors Team. The engineering technical review portion of the presentation is the primary focus of the overall presentation and will address the definition of a design review, execution guidance, the essential stages of a technical review, and the overall review planning life cycle. Examples of a technical review plan content, review approaches, review schedules, and the review process will be provided and discussed. The human factors portion of the presentation will focus on the NASA guidance for human factors. Human factors definition, categories, design guidance, and human factor specialist roles will be addressed. In addition, the NASA Systems Engineering Engine description, definition, and application will be reviewed as background leading into the NASA Project Life Cycle Overview and technical review planning discussion.

  13. Elliptic flow: a brief review

    NASA Astrophysics Data System (ADS)

    Snellings, Raimond

    2011-05-01

    One of the fundamental questions in the field of subatomic physics is the question of what happens to matter at extreme densities and temperatures as may have existed in the first microseconds after the Big Bang and exists, perhaps, in the core of dense neutron stars. The aim of heavy-ion physics is to collide nuclei at very high energies and thereby create such a state of matter in the laboratory. The experimental program began in the 1990s with collisions made available at the Brookhaven Alternating Gradient Synchrotron (AGS) and the CERN Super Proton Synchrotron (SPS), and continued at the Brookhaven Relativistic Heavy-Ion Collider (RHIC) with the maximum center-of-mass energies of \\sqrt{s_{NN}} = 4.75 , 17.2 and 200 GeV, respectively. Collisions of heavy ions at the unprecedented energy of 2.76 TeV recently became available at the LHC collider at CERN. In this review, I give a brief introduction to the physics of ultrarelativistic heavy-ion collisions and discuss the current status of elliptic flow measurements.

  14. NASA Tech Briefs, February 2012

    NASA Technical Reports Server (NTRS)

    2012-01-01

    This issue contains the following briefs: (1) Optical Comb from a Whispering Gallery Mode Resonator for Spectroscopy and Astronomy Instruments Calibration (2) Real-Time Flight Envelope Monitoring System (3) Nemesis Autonomous Test System (4) Mirror Metrology Using Nano-Probe Supports (5) Automated Lab-on-a-Chip Electrophoresis System (6) Techniques for Down-Sampling a Measured Surface Height Map for Model Validation (7) Multi-Component, Multi-Point Interferometric Rayleigh/Mie Doppler Velocimeter (8) Frequency to Voltage Converter Analog Front-End Prototype (9) Dust-Tolerant Intelligent Electrical Connection System (10) Gigabit Ethernet Asynchronous Clock Compensation FIFO (11) High-Speed, Multi-Channel Serial ADC LVDS Interface for Xilinx Virtex-5 FPGA (12) Glovebox for GeoLab Subsystem in HDU1-PEM (13) Modified Process Reduces Porosity when Soldering in Reduced Gravity Environments (14) Use of Functionalized Carbon Nanotubes for Covalent Attachment of Nanotubes to Silicon (15) Flexible Plug Repair for Shuttle Wing Leading Edge (16) Three Dimensionally Interlinked, Dense, Solid Form of Single-Walled CNT Ropes (17) Axel Robotic Platform for Crater and Extreme Terrain Exploration (18) Site Tamper and Material Plow Tool - STAMP (19) Magnetic Interface for Segmented Mirror Assembly (20) Transpiration-Cooled Spacecraft-Insulation-Repair Fasteners (21) Fluorescence-Based Sensor for Monitoring Activation of Lunar Dust (22) Aperture Ion Source (23) Virtual Ultrasound Guidance for Inexperienced Operators (24) Model-Based Fault Diagnosis: Performing Root Cause and Impact Analyses in Real Time (25) Interactive Schematic Integration Within the Propellant System Modeling Environment (26) Magnetic and Electric Field Polarizations of Oblique Magnetospheric Chorus Waves (27) Variable Sampling Mapping.

  15. NASA Tech Briefs, January 2009

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Tech Briefs are short announcements of innovations originating from research and development activities of the National Aeronautics and Space Administration. They emphasize information considered likely to be transferable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. Topics covered include: The Radio Frequency Health Node Wireless Sensor System; Effects of Temperature on Polymer/Carbon Chemical Sensors; Small CO2 Sensors Operate at Lower Temperature; Tele-Supervised Adaptive Ocean Sensor Fleet; Synthesis of Submillimeter Radiation for Spectroscopy; 100-GHz Phase Switch/Mixer Containing a Slot-Line Transition; Generating Ka-Band Signals Using an X-Band Vector Modulator; SiC Optically Modulated Field-Effect Transistor; Submillimeter-Wave Amplifier Module with Integrated Waveguide Transitions; Metrology System for a Large, Somewhat Flexible Telescope; Economical Implementation of a Filter Engine in an FPGA; Improved Joining of Metal Components to Composite Structures; Machined Titanium Heat-Pipe Wick Structure; Gadolinia-Doped Ceria Cathodes for Electrolysis of CO2; Utilizing Ocean Thermal Energy in a Submarine Robot; Fuel-Cell Power Systems Incorporating Mg-Based H2 Generators; Alternative OTEC Scheme for a Submarine Robot; Sensitive, Rapid Detection of Bacterial Spores; Adenosine Monophosphate-Based Detection of Bacterial Spores; Silicon Microleaks for Inlets of Mass Spectrometers; CGH Figure Testing of Aspherical Mirrors in Cold Vacuums; Series-Coupled Pairs of Silica Microresonators; Precise Stabilization of the Optical Frequency of WGMRs; Formation Flying of Components of a Large Space Telescope; Laser Metrology Heterodyne Phase-Locked Loop; Spatial Modulation Improves Performance in CTIS; High-Performance Algorithm for Solving the Diagnosis Problem; Truncation Depth Rule-of-Thumb for Convolutional Codes; Efficient Method for Optimizing Placement of Sensors.

  16. CONVENTIONAL COMBUSTION ENVIRONMENTAL ASSESSMENT PROGRAM, EXECUTIVE BRIEFING

    EPA Science Inventory

    The brochure gives an executive briefing of EPA's Conventional Combustion Environmental Assessment (CCEA) Program. The CCEA Program was established recently to coordinate and integrate EPA's research and development efforts for assessing the environmental effects of pollutants fr...

  17. A Brief History of CME Science

    NASA Technical Reports Server (NTRS)

    Alexander, David; Richardson, Ian G.; Zurbuchen, Thomas H.

    2006-01-01

    We present here a brief summary of the rich heritage of observational and theoretical research leading to the development of our current understanding of the initiation, structure, and evolution of Coronal Mass Ejections.

  18. 17 CFR 171.26 - Answering brief.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... of the Commission, the answering brief may not exceed thirty five pages, exclusive of any table of contents, table of cases, index and appendix containing transcripts of testimony, exhibits, statutes,...

  19. 17 CFR 171.26 - Answering brief.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... of the Commission, the answering brief may not exceed thirty five pages, exclusive of any table of contents, table of cases, index and appendix containing transcripts of testimony, exhibits, statutes,...

  20. Cumulative Index to NASA Tech Briefs

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Tech Briefs are short announcements of new technology derived from the R&D activities of the National Aeronautics and Space Administration. This Index to NASA Tech Briefs lists the technological innovations derived from the U.S. space program and published during the period January through December 1968. A new five year cycle of cumulative indexes begins with this index. The main section is arranged in six categories: Electrical (Electronic); Physical Sciences (Energy Sources); Materials (Chemistry); Life Sciences; Mechanical; and Computer Programs.

  1. 46 CFR 201.155 - Briefs; request for findings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Briefs; request for findings. 201.155 Section 201.155... PRACTICE AND PROCEDURE Briefs, Requests for Findings, Decisions, Exceptions (Rule 16) § 201.155 Briefs; request for findings. The time for filing briefs to the presiding officer, and extensions thereof,...

  2. 16 CFR 1502.34 - Briefs and arguments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Briefs and arguments. 1502.34 Section 1502... REGULATIONS PROCEDURES FOR FORMAL EVIDENTIARY PUBLIC HEARING Hearing Procedures § 1502.34 Briefs and arguments... schedule for the filing of briefs. Briefs are to be filed ordinarily within 45 days of the close of...

  3. 29 CFR 458.86 - Filing of brief.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Filing of brief. 458.86 Section 458.86 Labor Regulations... OF CONDUCT Hearing and Related Matters § 458.86 Filing of brief. Any party desiring to submit a brief... Law Judge may grant a reasonable extension of time. Copies of such brief shall be served on all of...

  4. 46 CFR 502.221 - Briefs; requests for findings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Briefs; requests for findings. 502.221 Section 502.221... Briefs; Requests for Findings; Decisions; Exceptions § 502.221 Briefs; requests for findings. (a) The presiding officer shall fix the time and manner of filing briefs and any enlargement of time. The period...

  5. 29 CFR 458.86 - Filing of brief.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false Filing of brief. 458.86 Section 458.86 Labor Regulations... OF CONDUCT Hearing and Related Matters § 458.86 Filing of brief. Any party desiring to submit a brief... Law Judge may grant a reasonable extension of time. Copies of such brief shall be served on all of...

  6. 18 CFR 1308.39 - Briefs and motions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Briefs and motions... DISPUTES Prehearing and Hearing Procedures § 1308.39 Briefs and motions. (a) All motions shall be accompanied by a brief or memorandum setting forth supporting authorities. Briefs in opposition to a...

  7. 22 CFR 1422.14 - Filing of briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Filing of briefs. 1422.14 Section 1422.14... PROCEEDINGS § 1422.14 Filing of briefs. A party desiring to file a brief with the Board shall file the... brief under authority of this section shall be made to the Regional Director, in writing, and...

  8. 16 CFR 1502.34 - Briefs and arguments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Briefs and arguments. 1502.34 Section 1502... REGULATIONS PROCEDURES FOR FORMAL EVIDENTIARY PUBLIC HEARING Hearing Procedures § 1502.34 Briefs and arguments... schedule for the filing of briefs. Briefs are to be filed ordinarily within 45 days of the close of...

  9. 18 CFR 1308.39 - Briefs and motions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Briefs and motions... DISPUTES Prehearing and Hearing Procedures § 1308.39 Briefs and motions. (a) All motions shall be accompanied by a brief or memorandum setting forth supporting authorities. Briefs in opposition to a...

  10. 40 CFR 179.98 - Briefs and arguments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Briefs and arguments. 179.98 Section... EVIDENTIARY PUBLIC HEARING Hearing Procedures § 179.98 Briefs and arguments. (a) Promptly after the taking of evidence is completed, the presiding officer will announce a schedule for the filing of briefs. Briefs...

  11. 22 CFR 1423.25 - Filing of brief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Filing of brief. 1423.25 Section 1423.25 Foreign... PROCEEDINGS § 1423.25 Filing of brief. Any party desiring to submit a brief to the Administrative Law Judge... Judge, but not in excess of thirty (30) days from the close of the hearing. Copies of any brief shall...

  12. 46 CFR 201.155 - Briefs; request for findings.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Briefs; request for findings. 201.155 Section 201.155... PRACTICE AND PROCEDURE Briefs, Requests for Findings, Decisions, Exceptions (Rule 16) § 201.155 Briefs; request for findings. The time for filing briefs to the presiding officer, and extensions thereof,...

  13. 40 CFR 179.98 - Briefs and arguments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Briefs and arguments. 179.98 Section... EVIDENTIARY PUBLIC HEARING Hearing Procedures § 179.98 Briefs and arguments. (a) Promptly after the taking of evidence is completed, the presiding officer will announce a schedule for the filing of briefs. Briefs...

  14. 22 CFR 1422.14 - Filing of briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Filing of briefs. 1422.14 Section 1422.14... PROCEEDINGS § 1422.14 Filing of briefs. A party desiring to file a brief with the Board shall file the... brief under authority of this section shall be made to the Regional Director, in writing, and...

  15. 21 CFR 12.96 - Briefs and arguments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Briefs and arguments. 12.96 Section 12.96 Food and... PUBLIC HEARING Hearing Procedures § 12.96 Briefs and arguments. (a) Promptly after the taking of evidence is completed, the presiding officer will announce a schedule for the filing of briefs. Briefs are...

  16. 22 CFR 1423.25 - Filing of brief.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Filing of brief. 1423.25 Section 1423.25 Foreign... PROCEEDINGS § 1423.25 Filing of brief. Any party desiring to submit a brief to the Administrative Law Judge... Judge, but not in excess of thirty (30) days from the close of the hearing. Copies of any brief shall...

  17. 39 CFR 958.15 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Post-hearing briefs. 958.15 Section 958.15 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PRACTICE IN PROCEEDINGS RELATIVE TO CIVIL... briefs. Post-hearing briefs and reply briefs may be submitted upon such terms as established by...

  18. 21 CFR 12.96 - Briefs and arguments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Briefs and arguments. 12.96 Section 12.96 Food and... PUBLIC HEARING Hearing Procedures § 12.96 Briefs and arguments. (a) Promptly after the taking of evidence is completed, the presiding officer will announce a schedule for the filing of briefs. Briefs are...

  19. 39 CFR 962.18 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Post-hearing briefs. 962.18 Section 962.18 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PRACTICE IN PROCEEDINGS RELATIVE TO THE PROGRAM FRAUD CIVIL REMEDIES ACT § 962.18 Post-hearing briefs. Post-hearing briefs and reply briefs may...

  20. 46 CFR 502.221 - Briefs; requests for findings.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 9 2011-10-01 2011-10-01 false Briefs; requests for findings. 502.221 Section 502.221... Briefs; Requests for Findings; Decisions; Exceptions § 502.221 Briefs; requests for findings. (a) The presiding officer shall fix the time and manner of filing briefs and any enlargement of time. The period...

  1. 17 CFR 201.450 - Briefs filed with the Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... filed with the Commission. (a) Briefing schedule order. Other than review ordered pursuant to § 201.431... determines to grant review as a matter of discretion, the Commission shall issue a briefing schedule order... briefing should be limited or directed. Unless otherwise provided, opening briefs shall be filed within...

  2. 20 CFR 355.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... REGULATIONS UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Post-hearing briefs. 355.36 Section...

  3. 42 CFR 3.544 - Post hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.544 Post hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 42 Public Health 1 2013-10-01 2013-10-01 false Post hearing briefs. 3.544 Section 3.544...

  4. 42 CFR 3.544 - Post hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.544 Post hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 42 Public Health 1 2012-10-01 2012-10-01 false Post hearing briefs. 3.544 Section 3.544...

  5. 42 CFR 3.544 - Post hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.544 Post hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 42 Public Health 1 2014-10-01 2014-10-01 false Post hearing briefs. 3.544 Section 3.544...

  6. 20 CFR 355.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... REGULATIONS UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Post-hearing briefs. 355.36 Section...

  7. 38 CFR 42.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) STANDARDS IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Post-hearing briefs....

  8. 42 CFR 1005.19 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... APPEALS OF EXCLUSIONS, CIVIL MONEY PENALTIES AND ASSESSMENTS § 1005.19 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 42 Public Health 5 2012-10-01 2012-10-01 false Post-hearing briefs. 1005.19 Section 1005.19...

  9. 40 CFR 27.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... § 27.36 Post-hearing briefs. The presiding officer may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The presiding officer shall fix the time for... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Post-hearing briefs. 27.36 Section...

  10. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Post-hearing briefs. 185.136 Section...

  11. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Post-hearing briefs. 185.136 Section 185... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  12. 38 CFR 42.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Post-hearing briefs. 42...) STANDARDS IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief....

  13. 39 CFR 958.15 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Post-hearing briefs. 958.15 Section 958.15 Postal... PENALTIES, CLEAN-UP COSTS AND DAMAGES FOR VIOLATION OF HAZARDOUS MATERIAL REGULATIONS § 958.15 Post-hearing briefs. Post-hearing briefs and reply briefs may be submitted upon such terms as established by...

  14. 40 CFR 27.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Post-hearing briefs. 27.36 Section 27... § 27.36 Post-hearing briefs. The presiding officer may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The presiding officer shall fix the time...

  15. 38 CFR 42.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Post-hearing briefs. 42...) STANDARDS IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief....

  16. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Post-hearing briefs. 185.136 Section 185... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  17. 38 CFR 42.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Post-hearing briefs. 42...) STANDARDS IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief....

  18. 39 CFR 962.18 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Post-hearing briefs. 962.18 Section 962.18 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PRACTICE IN PROCEEDINGS RELATIVE TO THE PROGRAM FRAUD CIVIL REMEDIES ACT § 962.18 Post-hearing briefs. Post-hearing briefs and reply briefs may...

  19. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Post-hearing briefs. 185.136 Section 185... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  20. 39 CFR 962.18 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Post-hearing briefs. 962.18 Section 962.18 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PRACTICE IN PROCEEDINGS RELATIVE TO THE PROGRAM FRAUD CIVIL REMEDIES ACT § 962.18 Post-hearing briefs. Post-hearing briefs and reply briefs may...

  1. 5 CFR 185.136 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Post-hearing briefs. 185.136 Section 185... CIVIL REMEDIES § 185.136 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  2. 40 CFR 27.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Post-hearing briefs. 27.36 Section 27... § 27.36 Post-hearing briefs. The presiding officer may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The presiding officer shall fix the time...

  3. 38 CFR 42.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Post-hearing briefs. 42...) STANDARDS IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief....

  4. 39 CFR 958.15 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Post-hearing briefs. 958.15 Section 958.15 Postal... PENALTIES, CLEAN-UP COSTS AND DAMAGES FOR VIOLATION OF HAZARDOUS MATERIAL REGULATIONS § 958.15 Post-hearing briefs. Post-hearing briefs and reply briefs may be submitted upon such terms as established by...

  5. 40 CFR 27.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Post-hearing briefs. 27.36 Section 27... § 27.36 Post-hearing briefs. The presiding officer may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The presiding officer shall fix the time...

  6. 40 CFR 27.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Post-hearing briefs. 27.36 Section 27... § 27.36 Post-hearing briefs. The presiding officer may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The presiding officer shall fix the time...

  7. 20 CFR 498.219 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Post-hearing briefs. 498.219 Section 498.219... EXCLUSIONS § 498.219 Post-hearing briefs. (a) Any party may file a post-hearing brief. (b) The ALJ may require the parties to file post-hearing briefs and may permit the parties to file reply briefs. (c)...

  8. 22 CFR 521.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... § 521.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time not... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Post-hearing briefs. 521.36 Section...

  9. 22 CFR 521.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... § 521.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time not... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Post-hearing briefs. 521.36 Section...

  10. 22 CFR 521.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... § 521.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time not... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Post-hearing briefs. 521.36 Section...

  11. 45 CFR 79.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not to... 45 Public Welfare 1 2012-10-01 2012-10-01 false Post-hearing briefs. 79.36 Section 79.36...

  12. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Post-hearing briefs. 224.36 Section...

  13. 45 CFR 79.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Post-hearing briefs. 79.36 Section 79.36 Public....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not...

  14. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Post-hearing briefs. 224.36 Section 224.36... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a...

  15. 22 CFR 521.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Post-hearing briefs. 521.36 Section 521.36... § 521.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time...

  16. 20 CFR 498.219 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Post-hearing briefs. 498.219 Section 498.219... EXCLUSIONS § 498.219 Post-hearing briefs. (a) Any party may file a post-hearing brief. (b) The ALJ may require the parties to file post-hearing briefs and may permit the parties to file reply briefs. (c)...

  17. 6 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Post-hearing briefs. 13.36 Section 13.36... § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ will fix the time for filing such briefs. Such...

  18. 45 CFR 79.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Post-hearing briefs. 79.36 Section 79.36 Public....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not...

  19. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Post-hearing briefs. 224.36 Section 224.36... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a...

  20. 6 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Post-hearing briefs. 13.36 Section 13.36... § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ will fix the time for filing such briefs. Such...

  1. 15 CFR 25.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Post-hearing briefs. 25.36 Section 25....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not...

  2. 20 CFR 498.219 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Post-hearing briefs. 498.219 Section 498.219... EXCLUSIONS § 498.219 Post-hearing briefs. (a) Any party may file a post-hearing brief. (b) The ALJ may require the parties to file post-hearing briefs and may permit the parties to file reply briefs. (c)...

  3. 28 CFR 71.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Post-hearing briefs. 71.36 Section 71.36....36 Post-hearing briefs. ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not to exceed...

  4. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Post-hearing briefs. 224.36 Section 224.36... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a...

  5. 20 CFR 498.219 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Post-hearing briefs. 498.219 Section 498.219... EXCLUSIONS § 498.219 Post-hearing briefs. (a) Any party may file a post-hearing brief. (b) The ALJ may require the parties to file post-hearing briefs and may permit the parties to file reply briefs. (c)...

  6. 6 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Post-hearing briefs. 13.36 Section 13.36... § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ will fix the time for filing such briefs. Such...

  7. 15 CFR 25.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Post-hearing briefs. 25.36 Section 25....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not...

  8. 45 CFR 79.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Post-hearing briefs. 79.36 Section 79.36 Public....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not...

  9. 28 CFR 71.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Post-hearing briefs. 71.36 Section 71.36....36 Post-hearing briefs. ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not to exceed...

  10. 22 CFR 224.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Post-hearing briefs. 224.36 Section 224.36... ACT § 224.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a...

  11. 6 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Post-hearing briefs. 13.36 Section 13.36... § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ will fix the time for filing such briefs. Such...

  12. 28 CFR 71.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Post-hearing briefs. 71.36 Section 71.36....36 Post-hearing briefs. ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not to exceed...

  13. 15 CFR 25.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Post-hearing briefs. 25.36 Section 25....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not...

  14. 45 CFR 79.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Post-hearing briefs. 79.36 Section 79.36 Public....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not...

  15. 15 CFR 25.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Post-hearing briefs. 25.36 Section 25....36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such briefs, not...

  16. 22 CFR 521.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Post-hearing briefs. 521.36 Section 521.36... § 521.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing briefs, at a time...

  17. Kawasaki disease: A brief history.

    PubMed

    Burns, J C; Kushner, H I; Bastian, J F; Shike, H; Shimizu, C; Matsubara, T; Turner, C L

    2000-08-01

    Tomisaku Kawasaki published the first English-language report of 50 patients with Kawasaki disease (KD) in 1974. Since that time, KD has become the leading cause of acquired heart disease among children in North America and Japan. Although an infectious agent is suspected, the cause remains unknown. However, significant progress has been made toward understanding the natural history of the disease and therapeutic interventions have been developed that halt the immune-mediated destruction of the arterial wall. We present a brief history of KD, review progress in research on the disease, and suggest avenues for future study. Kawasaki saw his first case of KD in January 1961 and published his first report in Japanese in 1967. Whether cases existed in Japan before that time is currently under study. The most significant controversy in the 1960s in Japan was whether the rash and fever sign/symptom complex described by Kawasaki was connected to subsequent cardiac complications in a number of cases. Pathologist Noboru Tanaka and pediatrician Takajiro Yamamoto disputed the early assertion of Kawasaki that KD was a self-limited illness with no sequelae. This controversy was resolved in 1970 when the first Japanese nationwide survey of KD documented 10 autopsy cases of sudden cardiac death after KD. By the time of the first English-language publication by Kawasaki in 1974, the link between KD and coronary artery vasculitis was well-established. KD was independently recognized as a new and distinct condition in the early 1970s by pediatricians Marian Melish and Raquel Hicks at the University of Hawaii. In 1973, at the same Hawaiian hospital, pathologist Eunice Larson, in consultation with Benjamin Landing at Los Angeles Children's Hospital, retrospectively diagnosed a 1971 autopsy case as KD. The similarity between KD and infantile periarteritis nodosa (IPN) was apparent to these pathologists, as it had been to Tanaka earlier. What remains unknown is the reason for the

  18. 45 CFR 156.951 - Posthearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Posthearing briefs. 156.951 Section 156.951 Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE ISSUER STANDARDS UNDER THE AFFORDABLE CARE ACT, INCLUDING STANDARDS RELATED TO...

  19. Bertrand Price Undercutting: A Brief Classroom Demonstration.

    ERIC Educational Resources Information Center

    Ortmann, Andreas

    2003-01-01

    Presents a brief classroom demonstration illustrating Bertrand price undercutting by outlining the experiment, discussing the game theory solution and experiences, and presenting related literatures. States that students remember the lesson because of the significant amounts of money each could have earned. (JEH)

  20. Partnerships: Sharing Responsibility for Children. Policy Briefs.

    ERIC Educational Resources Information Center

    Gregg, Soleil

    Because increasing numbers of children come to school with problems caused by poverty, divorce, drug use, and teenage pregnancy, schools may no longer be able to limit themselves solely to academic roles. This brief argues that schools, families, and communities need to work together to help children overcome the challenges that they face. It also…

  1. Characteristics of Improved School Districts. Research Brief

    ERIC Educational Resources Information Center

    Center for Comprehensive School Reform and Improvement, 2006

    2006-01-01

    This research brief presents an overview of a 2004 study by G.S. Shannon and P. Bylsma entitled "Characteristics of Improved School Districts: Themes from Research" (Olympia, WA: Office of Superintendent of Public Instruction). The authors reviewed more than 80 research articles that investigated the attributes of schools and districts that have…

  2. Valentine's Day: a Brief History and Game

    ERIC Educational Resources Information Center

    Maxwell, D. Jackson

    2009-01-01

    Valentine's Day presents an opportunity to show loved ones they are appreciated. Sweethearts, spouses, and families exchange gifts to express affection. Beyond traditional celebrations, new customs such as a romantic dinner, attending movies, and exchanging jewelry have been added. This article presents a brief history of Valentine's Day and a…

  3. A BRIEF ORAL OVERVIEW OF ENVIRONMENTAL ECONOMICS

    EPA Science Inventory

    A brief 1 hour oral presentation to professional staff of Cincinnati Nature Center is intended to provide a lay audience with a general understanding of how market-based approaches to environmental protection can meet (or exceed) regulatory efforts at enforcing pollution standard...

  4. 20 CFR 802.213 - Reply briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Reply briefs. 802.213 Section 802.213 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR RULES OF PRACTICE AND PROCEDURE Prereview..., memorandum, or statement submitted in response to the petition for review pursuant to § 802.212, any...

  5. Quality Physical Education. NASPE Resource Brief

    ERIC Educational Resources Information Center

    National Association for Sport and Physical Education, 2013

    2013-01-01

    A quality physical education program provides learning opportunities, appropriate instruction, meaningful and challenging content, and student and program assessment. In addition, a quality physical education improves mental alertness, academic performance, and readiness and enthusiasm for learning in the nation's youth. This brief provides a list…

  6. Decentralization and Policy Design. CPRE Policy Briefs.

    ERIC Educational Resources Information Center

    Consortium for Policy Research in Education, New Brunswick, NJ.

    This policy brief focuses on design issues surrounding decentralization policies, drawing from the following three reports: "Working Models of Choice in Public Education," by Richard F. Elmore; "Diversity Amidst Standardization: State Differential Treatment of Districts," by Susan H. Fuhrman; and "School District Restructuring in Santa Fe, New…

  7. Educational Access in Bangladesh. Country Policy Brief

    ERIC Educational Resources Information Center

    Ahmed, Manzoor

    2008-01-01

    This Policy Brief describes and explains patterns of access to schooling in Bangladesh. It outlines types of educational provision and provides some basic statistics on access, vulnerability and exclusion, as well as insights into the characteristics of those denied access. It is based on findings from the "Country Analytic Review on Access to…

  8. Greenhouse Gas Monitoring Technologies Technology Brief

    EPA Science Inventory

    This is a Technology Brief for the ETV Program. The EPA Environmental Technology Verification Program (ETV) develops test protocols and verifies the performance of innovative technologies that have the potential to improve protection of human health and the environment. The progr...

  9. Optical Disk Formats: A Briefing. ERIC Digest.

    ERIC Educational Resources Information Center

    Schamber, Linda

    This digest begins with a brief description and review of the development of optical disks. Optical disk formats are then described by capability: Read Only Memory (ROM), Write Once, Read Many (WORM), Interactive (I), and Erasable (E); forms of information (audio, text or data, video or graphics, or a combination); and disk size (most often 12 or…

  10. A brief history of astronomy: 1905 2005

    NASA Astrophysics Data System (ADS)

    Martin, Paula

    2005-03-01

    Einstein published his seminal papers in 1905. This article begins by introducing the impact of the theory of relativity on astronomy in the early 20th century. It goes on to discuss some of the major developments in astronomy over the past 100 years, and concludes with a brief look at what we still donÂ't know.

  11. Trouble Brewing in San Francisco. Policy Brief

    ERIC Educational Resources Information Center

    Buck, Stuart

    2010-01-01

    The city of San Francisco will face enormous budgetary pressures from the growing deficits in public pensions, both at a state and local level. In this policy brief, the author estimates that San Francisco faces an aggregate $22.4 billion liability for pensions and retiree health benefits that are underfunded--including $14.1 billion for the city…

  12. Trouble Brewing in Los Angeles. Policy Brief

    ERIC Educational Resources Information Center

    Buck, Stuart

    2010-01-01

    The city of Los Angeles will face enormous budgetary pressures from the growing deficits in public pensions, both at a state and local level. In this policy brief, the author estimates that Los Angeles faces a total $152.6 billion liability for pensions that are underfunded--including $49.1 billion for the city pension systems, $2.4 billion for…

  13. CTE's Role in Worker Retraining. Issue Brief

    ERIC Educational Resources Information Center

    Association for Career and Technical Education (NJ1), 2010

    2010-01-01

    This Issue Brief will explore the essential role that career and technical education programs play in addressing many of the issues faced by unemployed and underemployed workers. These programs target the adult learner through short-term and accelerated courses; utilize flexible learning approaches to account for students' other responsibilities;…

  14. Universities and Development: Global Cooperation. Policy Briefing

    ERIC Educational Resources Information Center

    Universities UK, 2010

    2010-01-01

    This policy briefing aims to demonstrate that universities are key organisations in international development. Universities are involved in a wide range of international development activities, including collaborative research projects, developing entrepreneurial and employability skills and the evaluation of non-governmental organisation (NGO)…

  15. A brief genomic history of tomato breeding

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Here we report a brief genomic history of tomato breeding by analyzing the genomes of 360 diverse accessions collected all over the world. These included 333 accessions from the red fruited clade (S. pimpinellifolium, S. l. var. cerasiforme, and S. lycopersicum) that represent various geographical o...

  16. LONGSCAN Research Briefs, Volume 1, Summer 1998.

    ERIC Educational Resources Information Center

    Hunter, Wanda, Comp.; Knight, Elizabeth, Comp.

    The Consortium of Longitudinal Studies in Child Abuse and Neglect (LONGSCAN) brings together five long-term studies of child maltreatment that utilize common procedures and instrumentation. Although each site is a separate project, collaboration permits exploration of additional issues and replication of findings. This paper provides brief reports…

  17. Trouble Brewing in Orange County. Policy Brief

    ERIC Educational Resources Information Center

    Buck, Stuart

    2010-01-01

    Orange County will soon face enormous budgetary pressures from the growing deficits in public pensions, both at a state and local level. In this policy brief, the author estimates that Orange County faces a total $41.2 billion liability for retiree benefits that are underfunded--including $9.4 billion for the county pension system and an estimated…

  18. Counseling Services and Student Success. Research Brief

    ERIC Educational Resources Information Center

    Francis, Perry C.; Horn, Aaron S.

    2016-01-01

    The purpose of this research brief is to provide an overview of mental health issues and counseling services on college campuses. The findings from several national surveys are reviewed to estimate the prevalence of anxiety and depression, suicide and suicidal ideation, and violence among college students. Common prevention and treatment programs…

  19. Genre Identification of Very Brief Musical Excerpts

    ERIC Educational Resources Information Center

    Mace, Sandra T.; Wagoner, Cynthia L.; Teachout, David J.; Hodges, Donald A.

    2012-01-01

    The purpose of this study was to examine how well individuals were able to identify different music genres from very brief excerpts and whether musical training, gender and preference played a role in genre identification. Listeners were asked to identify genre from classical, jazz, country, metal, and rap/hip hop excerpts that were 125, 250, 500,…

  20. Competency-Based Business Degree. Issue Brief

    ERIC Educational Resources Information Center

    Washington State Board for Community and Technical Colleges, 2014

    2014-01-01

    In January 2015, thirteen Washington community colleges launched an online, competency-based business transfer degree--the first in the state's community and technical college system. This issue brief provides answers to commonly asked questions about the new competency-based degree.

  1. Rhode Island KIDS COUNT Issue Brief, 1996.

    ERIC Educational Resources Information Center

    Bryant, Elizabeth Burke, Ed.; Walsh, Catherine Boisvert, Ed.

    1996-01-01

    These two Kids Count brief reports discuss issues related to the well-being of Rhode Island children. The first report identifies ways to measure the impact of state and federal welfare reform proposals on children who receive benefits through Aid to Families with Dependent Children (AFDC). Potential measures of success for welfare reform include…

  2. NASA Ames Fluid Mechanics Laboratory research briefs

    NASA Technical Reports Server (NTRS)

    Davis, Sanford (Editor)

    1994-01-01

    The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

  3. 37 CFR 41.37 - Appeal brief.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... named inventor or inventors are themselves the real party in interest. If an appeal brief does not contain a statement of the real party in interest, the Office may assume that the named inventor or inventors are the real party in interest. (ii) Related appeals and interferences. A statement identifying...

  4. Attention Deficit Disorder. NICHCY Briefing Paper.

    ERIC Educational Resources Information Center

    Fowler, Mary

    This briefing paper uses a question-and-answer format to provide basic information about children with attention deficit disorder (ADD). Questions address the following concerns: nature and incidence of ADD; causes of ADD; signs of ADD (impulsivity, hyperactivity, disorganization, social skill deficits); the diagnostic ADD assessment; how to get…

  5. Promoting Effective Preschool Programs. Policy Brief

    ERIC Educational Resources Information Center

    Karoly, Lynn; Zellman, Gail; Li, Jennifer

    2009-01-01

    This is one in a series of policy briefs on key education issues prepared by the RAND Corporation for the Obama administration. Preschool education plays an important role in increasing school readiness and closing achievement gaps for children at risk. However, access to high-quality preschool programs varies greatly. Therefore, policymakers…

  6. A Brief History of the Flathead Tribes.

    ERIC Educational Resources Information Center

    Woodcock, Clarence; And Others

    A source document, illustrated with many black and white photographs of tribe members and activities, provides a brief history of the American Indian tribes, now called the Flatheads, living on the Flathead Indian Reservation in Montana and describes some of their cultural traditions, particularly their ceremonial dances. The booklet traces the…

  7. Brief Introductory Psychology Textbooks: A Current Analysis.

    ERIC Educational Resources Information Center

    Griggs, Richard A.; Koenig, Cynthia S.

    2001-01-01

    Presents a comparative analysis of 15 brief introductory psychology textbooks for teachers who want a leaner introductory text. Focuses on length, pedagogical aids, and topic coverage. States that there is enough variability among the texts to accommodate teachers' preferences and needs. Includes a bibliography of the textbooks. (CMK)

  8. Supporting Adolescent Literacy Achievement. Issue Brief

    ERIC Educational Resources Information Center

    Berman, Ilene

    2009-01-01

    This brief enhances recommendations and policy strategies from the National Governors Association Center for Best Practices (NGA Center) publication "Reading to Achieve: A Governor's Guide to Adolescent Literacy". It reflects lessons from recent research and best practices from states selected to receive NGA Center support to develop statewide…

  9. A Brief Response to Gorard and Fitz

    ERIC Educational Resources Information Center

    Noden, Philip; Goldstein, Harvey

    2007-01-01

    This is a brief response to some of the issues raised by Gorard and Fitz in their paper, "What counts as evidence in the school choice debate?" published in the "British Educational Research Journal" v32, n6, 2006. Gorard and Fitz claim a "basic arithmetic error" (p. 807) in giving equal weighting to all LEAs (Noden, 2000). The authors would not…

  10. Reinventing Teacher Compensation Systems. CPRE Finance Briefs.

    ERIC Educational Resources Information Center

    Kelley, Carolyn; Odden, Allan

    Other organizations in the United States have successfully implemented new compensation structures. This publication argues that it is time for education to join these successful efforts and revise teacher-pay systems. The brief provides a short history of changes in teacher compensation over the last century and a discussion of key organizational…

  11. The Internet and Careers Work. NICEC Briefing.

    ERIC Educational Resources Information Center

    Offer, Marcus; Watts, Tony

    This briefing reviews the state of the art in the application of the Internet in career guidance and counseling. It describes how the Internet works and the main services offered: electronic mail, newsgroups, the World Wide Web, file transfer, and intranets. A glossary is provided. The following current and potential uses are discussed: access to…

  12. Pseudoangiomatous stromal hyperplasia (PASH): a brief review.

    PubMed

    Jaunoo, S S; Thrush, S; Dunn, P

    2011-01-01

    Pseudoangiomatous stromal hyperplasia (PASH) is a benign entity of the breast and typically found incidentally. It warrants thorough investigation in order to exclude more sinister pathology masquerading as this form of benign breast disease and can often be managed expectantly without the need for surgical intervention. We provide a brief review of the literature on PASH, discussing its clinicopathological features and management. PMID:20887819

  13. Family Incomes in Trouble. Briefing Paper.

    ERIC Educational Resources Information Center

    Economic Policy Inst., Washington, DC.

    This briefing paper presents statistical evidence from a variety of data sources that the real income of the average U.S. household has been stagnant for a decade; primary causes are also examined. The major reasons identified for income stagnation are (1) declining real wages; (2) a less productive economy (economic growth has slowed down)…

  14. Grammar Schools: Brief Flowering of Social Mobility?

    ERIC Educational Resources Information Center

    Barker, Bernard

    2012-01-01

    Grammar schools are increasingly remembered, especially by right-wing ideologues, as the agents of a "brief flowering" of post-war social mobility. This article presents statistical, documentary and interview evidence of secondary education in the eleven plus era, and finds nothing to justify the claim that selective schools produced a general…

  15. The Neighboring Field of Brief Individual Psychotherapy.

    ERIC Educational Resources Information Center

    Gustafson, Jim

    1987-01-01

    Presents field of brief individual psychotherapy as coherent set of conventions, despite its diverse origins in schools of dynamic, behavioral, interpersonal or cognitive, and strategic psychotherapy. Proposes advantages and drawbacks of shared conventions and discusses how neighboring field could help field of family therapy reduce its errors.…

  16. A BRIEF HINDI REFERENCE GRAMMAR. PRELIMINARY VERSION.

    ERIC Educational Resources Information Center

    GUMPERZ, JOHN J.; MISRA, VIDYA NIWAS

    THIS BRIEF OUTLINE OF HINDI PHONOLOGY AND GRAMMAR IS INTENDED FOR FIRST AND SECOND YEAR STUDENTS OF HINDI WHO HAVE SOME PREVIOUS KNOWLEDGE OF THE ORAL AND WRITTEN LANGUAGE BUT WHO MAY HAVE HAD NO PREVIOUS TRAINING IN LINGUISTIC TERMINOLOGY. THE AUTHORS HAVE THEREFORE EMPHASIZED SIMPLICITY AND READABILITY RATHER THAN EXHAUSTIVENESS OR ORIGINALITY…

  17. Teacher Retirement Systems: Research Findings. Research Brief

    ERIC Educational Resources Information Center

    Hansen, Janet S.; Podgursky, Michael J.; Costrell, Robert M.

    2009-01-01

    This policy brief summarizes findings presented at a February 2009 research conference on teacher retirement systems hosted by the National Center on Performance Incentives (NCPI) at Vanderbilt University's Peabody College. The 2009 conference was the second in a series of NCPI events focusing on findings from recent research on issues related to…

  18. A Brief History of the Armenian Genocide

    ERIC Educational Resources Information Center

    Cohan, Sara

    2005-01-01

    This article features a brief history of the Armenian genocide. The Armenians are an ancient people who have existed since before the first century C.E. Armenia has gained and lost a tremendous amount of territory throughout its long and turbulent history. Boundaries of the past have extended from that of the present-day Republic of Armenia and…

  19. Safe and Participatory Public Schools. Research Brief

    ERIC Educational Resources Information Center

    Rogers, John

    2010-01-01

    The California State Assembly is presently considering AB 2034 which would prohibit school districts, county offices of education (COEs), or charter schools that elect to fingerprint volunteers from allowing individuals who have been convicted of specific sex, drug or violent offenses to volunteer in schools. This policy brief aims to inform…

  20. District Awards for Teacher Excellence: Research Brief

    ERIC Educational Resources Information Center

    National Center on Performance Incentives, 2010

    2010-01-01

    Since 2008 Texas's District Awards for Teacher Excellence (D.A.T.E.) program has provided grants to districts for the implementation of locally designed incentive pay plans. The 2010-11 school year is the third year of the D.A.T.E. incentive pay plans with approximately $197 million in annual state funding. This research brief summarizes the key…

  1. Briefs for English-Speaking Parents, 1996.

    ERIC Educational Resources Information Center

    Howley, Craig

    In plain language, these six ready-to-copy briefs state what researchers and practitioners have learned about various ways parents can help their children do well in school. "Calculating the Risks: When Should Parents Add or Subtract?" discusses the normal risks of life, the intensification of risk by poverty, and how parents can keep children…

  2. 14 CFR 91.519 - Passenger briefing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Passenger briefing. 91.519 Section 91.519 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC... be supplemented by printed cards for the use of each passenger containing— (1) A diagram of,...

  3. 49 CFR 511.22 - Prehearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 6 2011-10-01 2011-10-01 false Prehearing briefs. 511.22 Section 511.22 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ADJUDICATIVE PROCEDURES Prehearing Procedures; Motions; Interlocutory Appeals; Summary Judgment; Settlement...

  4. The Wage Gap: Briefing Paper #1.

    ERIC Educational Resources Information Center

    National Committee on Pay Equity, Washington, DC.

    Women have made slow, steady progress in the labor market since 1979, but the wage gap has not narrowed significantly. This briefing paper updates a September 1987 paper based on "Male-Female Differences in Work Experience, Occupations, and Earnings: 1984" (Current Population Reports, Household Economic Studies, Series P-70, No. 10, issued in…

  5. Brief Experimental Analysis of Early Reading Interventions

    ERIC Educational Resources Information Center

    Petursdottir, Anna-Lind; McMaster, Kristen; McComas, Jennifer J.; Bradfield, Tracy; Braganza, Viveca; Koch-McDonald, Julie; Rodriguez, Roxana; Scharf, Haley

    2009-01-01

    The purpose of this study was to investigate how brief experimental analyses (BEAs) could be used to identify effective interventions for Kindergartners (2 girls and 2 boys, 5 years and 7-10 months old) with low performance and/or growth slope in letter sound fluency (LSF). Interventions were tested within a multielement design with brief…

  6. NASA Tech Briefs, October 2001. Volume 25, No. 10

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Topics include: special coverage section on composites and plastics, electronic components and systems, software, mechanics, physical sciences, information sciences, book and reports, and a special sections of Photonics Tech Briefs and Motion Control Tech Briefs.

  7. NASA Tech Briefs, December 2000. Volume 24, No. 12

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Topics include: special coverage sections on Imaging/Video/Display Technology, and sections on electronic components and systems, test and measurement, software, information sciences, and special sections of Electronics Tech Briefs and Motion Control Tech Briefs.

  8. 49 CFR 821.48 - Briefs and oral argument.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... party who has filed a notice of appeal fails to perfect the appeal by filing a timely appeal brief. (b.... The appeal brief shall set forth the name, address and telephone number of the party, or the...

  9. 49 CFR 821.48 - Briefs and oral argument.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... party who has filed a notice of appeal fails to perfect the appeal by filing a timely appeal brief. (b.... The appeal brief shall set forth the name, address and telephone number of the party, or the...

  10. 49 CFR 821.48 - Briefs and oral argument.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... party who has filed a notice of appeal fails to perfect the appeal by filing a timely appeal brief. (b.... The appeal brief shall set forth the name, address and telephone number of the party, or the...

  11. 49 CFR 821.48 - Briefs and oral argument.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... party who has filed a notice of appeal fails to perfect the appeal by filing a timely appeal brief. (b.... The appeal brief shall set forth the name, address and telephone number of the party, or the...

  12. NASA Tech Briefs, February 2002. Volume 26, No. 2

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include:a technology focus on computers, electronic components and systems, software, materials, mechanics,physical sciences machinery, manufacturing/fabrication, mathematics, book and reports, motion control tech briefs and a special section on Photonics Tech Briefs.

  13. NASA Tech Briefs, April 1999. Volume 23, No. 4

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Topics include: special coverage sections on automotive technology, and CAM and sections on electronic components and systems, software, materials, machinery/automation, physical sciences, and a special section of Electronic Tech Briefs and Motion Control Tech Briefs.

  14. ETV Tech Brief: Rapid Fungi and Bacteria Detection Technologies

    EPA Science Inventory

    Technical brief that summarizes the results for Mycometer, Inc. Mycometer®-test and Bactiquant®-test, which are rapid detection technologies for fungi and bacteria. The brief summarizes the results of the verification report and statement.

  15. 12 CFR 1081.403 - Briefs filed with the Director.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ADJUDICATION PROCEEDINGS Decision and Appeals § 1081.403 Briefs filed with the Director. (a) Contents of briefs... shall not exceed 15 pages, exclusive of pages containing the table of contents, table of...

  16. 12 CFR 1081.403 - Briefs filed with the Director.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ADJUDICATION PROCEEDINGS Decision and Appeals § 1081.403 Briefs filed with the Director. (a) Contents of briefs... shall not exceed 15 pages, exclusive of pages containing the table of contents, table of...

  17. 12 CFR 1081.403 - Briefs filed with the Director.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ADJUDICATION PROCEEDINGS Decision and Appeals § 1081.403 Briefs filed with the Director. (a) Contents of briefs... shall not exceed 15 pages, exclusive of pages containing the table of contents, table of...

  18. NASA Tech Briefs, September 1998. Volume 22, No. 9

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage on data acquisition, also, electronic components and circuits, electronic systems, software, materials, mechanics, machinery/automation, physical sciences, information sciences, This issue contains a special sections of Electronics Tech Briefs and Motion Control Tech Briefs.

  19. 31 CFR 16.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Post-hearing briefs. 16.36 Section 16... PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 16.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. The ALJ shall fix the time for filing such briefs, not to exceed 60 days...

  20. 7 CFR 1.334 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Hearings Under the Program Fraud Civil Remedies Act of 1986 § 1.334 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 7 Agriculture 1 2013-01-01 2013-01-01 false Post-hearing briefs. 1.334 Section 1.334...

  1. 10 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Post-hearing briefs. 13.36 Section 13.36 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ...

  2. 7 CFR 1.334 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Hearings Under the Program Fraud Civil Remedies Act of 1986 § 1.334 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 7 Agriculture 1 2012-01-01 2012-01-01 false Post-hearing briefs. 1.334 Section 1.334...

  3. 29 CFR 22.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Post-hearing briefs. 22.36 Section 22.36 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief....

  4. 29 CFR 22.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Post-hearing briefs. 22.36 Section 22.36 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief....

  5. 7 CFR 1.334 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Hearings Under the Program Fraud Civil Remedies Act of 1986 § 1.334 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief... 7 Agriculture 1 2011-01-01 2011-01-01 false Post-hearing briefs. 1.334 Section 1.334...

  6. 43 CFR 35.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CLAIMS AND STATEMENTS § 35.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing such... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Post-hearing briefs. 35.36 Section...

  7. 43 CFR 35.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Post-hearing briefs. 35.36 Section 35.36... CLAIMS AND STATEMENTS § 35.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  8. 10 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Post-hearing briefs. 13.36 Section 13.36 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ...

  9. 10 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Post-hearing briefs. 13.36 Section 13.36 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ...

  10. 31 CFR 16.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Post-hearing briefs. 16.36 Section 16... PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 16.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. The ALJ shall fix the time for filing such briefs, not to exceed 60 days...

  11. 43 CFR 35.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Post-hearing briefs. 35.36 Section 35.36... CLAIMS AND STATEMENTS § 35.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  12. 31 CFR 16.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Post-hearing briefs. 16.36 Section 16... PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 16.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. The ALJ shall fix the time for filing such briefs, not to exceed 60 days...

  13. 43 CFR 35.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Post-hearing briefs. 35.36 Section 35.36... CLAIMS AND STATEMENTS § 35.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  14. 10 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Post-hearing briefs. 13.36 Section 13.36 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ...

  15. 10 CFR 13.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Post-hearing briefs. 13.36 Section 13.36 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ...

  16. 43 CFR 35.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Post-hearing briefs. 35.36 Section 35.36... CLAIMS AND STATEMENTS § 35.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing brief. The ALJ shall fix the time for filing...

  17. OBSERVATIONS OF INFALLING AND ROTATIONAL MOTIONS ON A 1000 AU SCALE AROUND 17 CLASS 0 AND 0/I PROTOSTARS: HINTS OF DISK GROWTH AND MAGNETIC BRAKING?

    SciTech Connect

    Yen, Hsi-Wei; Koch, Patrick M.; Takakuwa, Shigehisa; Ho, Paul T. P.; Ohashi, Nagayoshi; Tang, Ya-Wen

    2015-02-01

    We perform imaging and analyses of SMA 1.3 mm continuum, C{sup 18}O (2-1) and {sup 12}CO (2-1) line data of 17 Class 0 and 0/I protostars to study their gas kinematics on a 1000 AU scale. Continuum and C{sup 18}O (2-1) emission are detected toward all the sample sources and show central primary components with sizes of ∼600-1500 AU associated with protostars. The velocity gradients in C{sup 18}O (2-1) have wide ranges of orientations from parallel to perpendicular to the outflows, with magnitudes from ∼1 to ∼530 km s{sup –1} pc{sup –1}. We construct a simple kinematic model to reproduce the observed velocity gradients, estimate the infalling and rotational velocities, and infer the disk radii and the protostellar masses. The inferred disk radii range from <5 AU to >500 AU with estimated protostellar masses from <0.1 M {sub ☉} to >1 M {sub ☉}. Our results hint that both large and small disks are possibly present around Class 0 protostars, which could be a sign of disk growth at the Class 0 stage. In addition, the directions of the overall velocity gradients in 7 out of the 17 sources are close to perpendicular to their outflow axes (Δθ > 65°), which is a signature of significant rotational motions. From our model fitting, the specific angular momenta in these sources are estimated to be >2 × 10{sup –4} km s{sup –1} pc, suggesting that magnetic braking is unlikely efficient on a 1000 AU scale in these Class 0 and 0/I sources. In a sub-sample with observed magnetic field orientations, we find no source with large specific angular momenta together with closely aligned magnetic field and outflow axes. This possibly hints that the magnetic field, if originally aligned with the rotational axis, can play a role in removing angular momentum from infalling material at the Class 0 stage. We discuss our results in comparison with theoretical models of collapsing dense cores with and without magnetic fields in the context of disk

  18. Observations of Infalling and Rotational Motions on a 1000 AU Scale around 17 Class 0 and 0/I Protostars: Hints of Disk Growth and Magnetic Braking?

    NASA Astrophysics Data System (ADS)

    Yen, Hsi-Wei; Koch, Patrick M.; Takakuwa, Shigehisa; Ho, Paul T. P.; Ohashi, Nagayoshi; Tang, Ya-Wen

    2015-02-01

    We perform imaging and analyses of SMA 1.3 mm continuum, C18O (2-1) and 12CO (2-1) line data of 17 Class 0 and 0/I protostars to study their gas kinematics on a 1000 AU scale. Continuum and C18O (2-1) emission are detected toward all the sample sources and show central primary components with sizes of ~600-1500 AU associated with protostars. The velocity gradients in C18O (2-1) have wide ranges of orientations from parallel to perpendicular to the outflows, with magnitudes from ~1 to ~530 km s-1 pc-1. We construct a simple kinematic model to reproduce the observed velocity gradients, estimate the infalling and rotational velocities, and infer the disk radii and the protostellar masses. The inferred disk radii range from <5 AU to >500 AU with estimated protostellar masses from <0.1 M ⊙ to >1 M ⊙. Our results hint that both large and small disks are possibly present around Class 0 protostars, which could be a sign of disk growth at the Class 0 stage. In addition, the directions of the overall velocity gradients in 7 out of the 17 sources are close to perpendicular to their outflow axes (Δθ > 65°), which is a signature of significant rotational motions. From our model fitting, the specific angular momenta in these sources are estimated to be >2 × 10-4 km s-1 pc, suggesting that magnetic braking is unlikely efficient on a 1000 AU scale in these Class 0 and 0/I sources. In a sub-sample with observed magnetic field orientations, we find no source with large specific angular momenta together with closely aligned magnetic field and outflow axes. This possibly hints that the magnetic field, if originally aligned with the rotational axis, can play a role in removing angular momentum from infalling material at the Class 0 stage. We discuss our results in comparison with theoretical models of collapsing dense cores with and without magnetic fields in the context of disk formation.

  19. 29 CFR 1603.303 - Briefs on appeal.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Briefs on appeal. 1603.303 Section 1603.303 Labor... THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Appeals § 1603.303 Briefs on appeal. (a) The appellant shall file a brief or other written statement within 30 days after the appeal is filed, unless...

  20. 48 CFR 6302.15 - Prehearing briefs (Rule 15).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Prehearing briefs (Rule 15... CONTRACT APPEALS RULES OF PROCEDURE 6302.15 Prehearing briefs (Rule 15). The Board may, in its discretion, require the parties to submit prehearing briefs in any case in which a hearing has been elected under...

  1. 39 CFR 3001.115 - Participant statement or brief.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Participant statement or brief. 3001.115 Section... Participant statement or brief. (a) Participant statement. Upon the filing of the petition for review of a... or she may file a brief as described in paragraph (b) of this section presenting the arguments,...

  2. 36 CFR 1150.101 - Posthearing briefs; proposed findings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Posthearing briefs; proposed... § 1150.101 Posthearing briefs; proposed findings. The judge shall fix the terms, including time, for filing post-hearing statements of position or briefs, which may contain proposed findings of fact...

  3. 39 CFR 3001.115 - Participant statement or brief.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Participant statement or brief. 3001.115 Section... Participant statement or brief. (a) Participant statement. Upon the filing of the petition for review of a... or she may file a brief as described in paragraph (b) of this section presenting the arguments,...

  4. 29 CFR 1603.303 - Briefs on appeal.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Briefs on appeal. 1603.303 Section 1603.303 Labor... THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Appeals § 1603.303 Briefs on appeal. (a) The appellant shall file a brief or other written statement within 30 days after the appeal is filed, unless...

  5. 19 CFR 207.15 - Written briefs and conference.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Written briefs and conference. 207.15 Section 207... SUBSIDIZED EXPORTS TO THE UNITED STATES Preliminary Determinations § 207.15 Written briefs and conference... issued pursuant to § 207.12 a written brief containing information and arguments pertinent to the...

  6. 36 CFR 1150.103 - Posthearing briefs, decision.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Posthearing briefs, decision. 1150.103 Section 1150.103 Parks, Forests, and Public Property ARCHITECTURAL AND TRANSPORTATION BARRIERS... Posthearing briefs, decision. (a) No briefs or posthearing statements of position shall be required...

  7. 25 CFR 11.804 - Briefs and memoranda.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Briefs and memoranda. 11.804 Section 11.804 Indians... ORDER CODE Appellate Proceedings § 11.804 Briefs and memoranda. (a) Within 30 days after the notice of appeal is filed, the appellant may file a written brief in support of his or her appeal. An original...

  8. 19 CFR 207.67 - Posthearing briefs and statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Posthearing briefs and statements. 207.67 Section... SUBSIDIZED EXPORTS TO THE UNITED STATES Five-Year Reviews § 207.67 Posthearing briefs and statements. (a) Briefs from parties. Any party to a five-year review may file with the Secretary a posthearing...

  9. 36 CFR 1150.103 - Posthearing briefs, decision.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Posthearing briefs, decision. 1150.103 Section 1150.103 Parks, Forests, and Public Property ARCHITECTURAL AND TRANSPORTATION BARRIERS... Posthearing briefs, decision. (a) No briefs or posthearing statements of position shall be required...

  10. 43 CFR 4.311 - Briefs on appeal.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Briefs on appeal. 4.311 Section 4.311... Appeal Before the Interior Board of Indian Appeals § 4.311 Briefs on appeal. (a) The appellant may file an opening brief within 30 days after receiving the notice of docketing. The appellant must...

  11. 19 CFR 207.15 - Written briefs and conference.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Written briefs and conference. 207.15 Section 207... SUBSIDIZED EXPORTS TO THE UNITED STATES Preliminary Determinations § 207.15 Written briefs and conference... issued pursuant to § 207.12 a written brief containing information and arguments pertinent to the...

  12. 24 CFR 180.665 - Arguments and briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Arguments and briefs. 180.665... Hearing § 180.665 Arguments and briefs. (a) Following the submission of evidence at an oral hearing, the parties may file a brief, proposed findings of fact and conclusions of law, or both, or, in the...

  13. 48 CFR 6302.15 - Prehearing briefs (Rule 15).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Prehearing briefs (Rule 15... CONTRACT APPEALS RULES OF PROCEDURE 6302.15 Prehearing briefs (Rule 15). The Board may, in its discretion, require the parties to submit prehearing briefs in any case in which a hearing has been elected under...

  14. 25 CFR 11.804 - Briefs and memoranda.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Briefs and memoranda. 11.804 Section 11.804 Indians... ORDER CODE Appellate Proceedings § 11.804 Briefs and memoranda. (a) Within 30 days after the notice of appeal is filed, the appellant may file a written brief in support of his or her appeal. An original...

  15. 36 CFR 1150.101 - Posthearing briefs; proposed findings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Posthearing briefs; proposed... § 1150.101 Posthearing briefs; proposed findings. The judge shall fix the terms, including time, for filing post-hearing statements of position or briefs, which may contain proposed findings of fact...

  16. 76 FR 44373 - Notice of Opportunity To File Amicus Briefs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ... BOARD Notice of Opportunity To File Amicus Briefs AGENCY: Merit Systems Protection Board (MSPB or Board). ACTION: Notice. SUMMARY: The Board announces the opportunity to file amicus briefs in the matters of... partially recovered employee as limited duty work? Interested parties may submit amicus briefs or...

  17. 43 CFR 4.311 - Briefs on appeal.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Briefs on appeal. 4.311 Section 4.311... Appeal Before the Interior Board of Indian Appeals § 4.311 Briefs on appeal. (a) The appellant may file an opening brief within 30 days after receiving the notice of docketing. The appellant must...

  18. 15 CFR 904.261 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Post-hearing briefs. 904.261 Section... PROCEDURES Hearing and Appeal Procedures Post-Hearing § 904.261 Post-hearing briefs. (a) The parties may file post-hearing briefs that include proposed findings of fact and conclusions of law within 30 days...

  19. 42 CFR 423.2120 - Filing briefs with the MAC.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Filing briefs with the MAC. 423.2120 Section 423..., and Judicial Review § 423.2120 Filing briefs with the MAC. Upon request, the MAC will give the enrollee requesting review a reasonable opportunity to file a brief or other written statement about...

  20. 15 CFR 930.127 - Briefs and supporting materials.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Briefs and supporting materials. 930... for Review Related to the Objectives of the Act and National Security Interests § 930.127 Briefs and... appellant shall submit to the Secretary its principal brief accompanied by the appendix described...

  1. 43 CFR 4.124 - Submission of briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Submission of briefs. 4.124 Section 4.124 Public Lands: Interior Office of the Secretary of the Interior DEPARTMENT HEARINGS AND APPEALS PROCEDURES... Submission of briefs. Posthearing briefs may be submitted upon such terms as may be agreed upon by...

  2. 75 FR 15689 - Streamlined Procedure for Appeal Brief Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... United States Patent and Trademark Office Streamlined Procedure for Appeal Brief Review AGENCY: United... Trademark Office (USPTO) is streamlining the procedure for the review of appeal briefs to increase the... responsibility for determining whether appeal briefs filed in patent applications comply with the...

  3. 14 CFR 125.327 - Briefing of passengers before flight.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Briefing of passengers before flight. 125... § 125.327 Briefing of passengers before flight. (a) Before each takeoff, each pilot in command of an... briefing shall include a statement that the Federal Aviation Regulations require passenger compliance...

  4. 14 CFR 121.573 - Briefing passengers: Extended overwater operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Briefing passengers: Extended overwater... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations § 121.573 Briefing passengers: Extended overwater operations. (a) In addition to the oral briefing required by §...

  5. 45 CFR 160.544 - Post hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Procedures for Hearings § 160.544 Post hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post-hearing... 45 Public Welfare 1 2012-10-01 2012-10-01 false Post hearing briefs. 160.544 Section...

  6. 49 CFR 31.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Post-hearing briefs. 31.36 Section 31.36 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a...

  7. 49 CFR 31.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Post-hearing briefs. 31.36 Section 31.36 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a...

  8. 41 CFR 105-70.036 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administration 70-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.036 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Post-hearing briefs....

  9. 14 CFR 1264.135 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FRAUD CIVIL PENALTIES ACT OF 1986 § 1264.135 Post-hearing briefs. The presiding officer may require the parties to file post-hearing briefs. In any event, upon approval of the presiding officer, any party may... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Post-hearing briefs. 1264.135 Section...

  10. 25 CFR 700.315 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false Post-hearing briefs. 700.315 Section 700.315 Indians THE... of Eligibility, Hearing and Administrative Review (Appeals) § 700.315 Post-hearing briefs. Applicants may submit post-hearing briefs or written comments to the Presiding Officer within fourteen days...

  11. 41 CFR 105-70.036 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Administration 70-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.036 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a post... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Post-hearing briefs....

  12. 22 CFR 35.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Post-hearing briefs. 35.36 Section 35.36 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party...

  13. 10 CFR 1013.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Post-hearing briefs. 1013.36 Section 1013.36 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file...

  14. 10 CFR 1013.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Post-hearing briefs. 1013.36 Section 1013.36 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file...

  15. 10 CFR 1013.36 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Post-hearing briefs. 1013.36 Section 1013.36 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file...

  16. 34 CFR 33.36 - Post-hearing briefs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Post-hearing briefs. 33.36 Section 33.36 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file...

  17. 25 CFR 700.315 - Post-hearing briefs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false Post-hearing briefs. 700.315 Section 700.315 Indians THE... of Eligibility, Hearing and Administrative Review (Appeals) § 700.315 Post-hearing briefs. Applicants may submit post-hearing briefs or written comments to the Presiding Officer within fourteen days...

  18. 10 CFR 1013.36 - Post-hearing briefs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Post-hearing briefs. 1013.36 Section 1013.36 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file...

  19. 49 CFR 31.36 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Post-hearing briefs. 31.36 Section 31.36 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a...

  20. 25 CFR 700.315 - Post-hearing briefs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Post-hearing briefs. 700.315 Section 700.315 Indians THE... of Eligibility, Hearing and Administrative Review (Appeals) § 700.315 Post-hearing briefs. Applicants may submit post-hearing briefs or written comments to the Presiding Officer within fourteen days...

  1. Georgia Health Policy Center Child Policy Briefs, 2002.

    ERIC Educational Resources Information Center

    2002

    This set of briefs discuss state public policy and implications as they pertain to children in Georgia. The three briefs each address a single topic. The first, on benefits of child care for low-income children in Georgia, advocates implementation of the Georgia Early Learning Initiative (GELI) and details the program. The second brief, on the…

  2. The Impact of Ultrasound on Developing Brain Neurons. Science Briefs

    ERIC Educational Resources Information Center

    National Scientific Council on the Developing Child, 2007

    2007-01-01

    "Science Briefs" summarize the findings and implications of a recent study in basic science or clinical research. This brief reports on the study. This Brief summarizes the findings and implications of "Prenatal Exposure to Ultrasound Waves Impacts Neuronal Migration in Mice" (E. S. B. C. Ang, Jr.; V. Gluncic; A. Duque; M. E. Schafer; and P.…

  3. 49 CFR 821.48 - Briefs and oral argument.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 7 2013-10-01 2013-10-01 false Briefs and oral argument. 821.48 Section 821.48 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL TRANSPORTATION SAFETY BOARD RULES OF PRACTICE IN AIR SAFETY PROCEEDINGS Appeal From Initial Decision § 821.48 Briefs and oral argument. (a) Appeal brief. Except...

  4. Toward Science-Practice Integration in Brief Counseling and Therapy.

    ERIC Educational Resources Information Center

    Steenbarger, Brett N.

    1992-01-01

    Outlines major approaches to brief counseling practice, including psychodynamic, cognitive-behavioral, and strategic; summarizes recent research on brief therapeutic outcomes and processes; and identifies overlapping themes in science and practice literatures. Offers integrative model of brief intervention, capable of being flexibly modified for…

  5. The Texas Public Education Challenge. Policy Brief No. 1

    ERIC Educational Resources Information Center

    Center for Public Policy Priorities, 2006

    2006-01-01

    This is the first in a trilogy of policy briefs discussing public education and taxes. This brief discusses the challenge facing Texas in funding public education. This brief also explains why the Texas Supreme Court's recent decision in "West Orange-Cove II" requires increased state appropriations for public education.

  6. 14 CFR 91.1013 - Operational control briefing and acknowledgment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Operational control briefing and... Ownership Operations Operational Control § 91.1013 Operational control briefing and acknowledgment. (a) Upon... management services contract, the program manager must brief the fractional owner on the owner's...

  7. 40 CFR 104.11 - Briefs and findings of fact.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Briefs and findings of fact. 104.11... HEARINGS ON EFFLUENT STANDARDS FOR TOXIC POLLUTANTS § 104.11 Briefs and findings of fact. At the conclusion... briefs and proposed findings of fact and conclusions. In establishing the aforesaid time schedule,...

  8. 40 CFR 104.11 - Briefs and findings of fact.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Briefs and findings of fact. 104.11... HEARINGS ON EFFLUENT STANDARDS FOR TOXIC POLLUTANTS § 104.11 Briefs and findings of fact. At the conclusion... briefs and proposed findings of fact and conclusions. In establishing the aforesaid time schedule,...

  9. 40 CFR 104.11 - Briefs and findings of fact.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Briefs and findings of fact. 104.11... HEARINGS ON EFFLUENT STANDARDS FOR TOXIC POLLUTANTS § 104.11 Briefs and findings of fact. At the conclusion... briefs and proposed findings of fact and conclusions. In establishing the aforesaid time schedule,...

  10. 40 CFR 104.11 - Briefs and findings of fact.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 23 2013-07-01 2013-07-01 false Briefs and findings of fact. 104.11... HEARINGS ON EFFLUENT STANDARDS FOR TOXIC POLLUTANTS § 104.11 Briefs and findings of fact. At the conclusion... briefs and proposed findings of fact and conclusions. In establishing the aforesaid time schedule,...

  11. 40 CFR 104.11 - Briefs and findings of fact.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Briefs and findings of fact. 104.11... HEARINGS ON EFFLUENT STANDARDS FOR TOXIC POLLUTANTS § 104.11 Briefs and findings of fact. At the conclusion... briefs and proposed findings of fact and conclusions. In establishing the aforesaid time schedule,...

  12. On the Integration of Science and Practice in Brief Psychotherapy.

    ERIC Educational Resources Information Center

    May, Robert

    1992-01-01

    Responds to previous article by Steenbarger on science-practice integration in brief counseling and therapy. Focuses specifically on the integration of science and practice in brief psychotherapy. Elaborates on agreements and disagreements concerning Steenbarger's analysis of brief psychotherapy. Muses over what is lost as well as gained in brief…

  13. 47 CFR 1.50 - Specifications as to briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Specifications as to briefs. 1.50 Section 1.50 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure Pleadings, Briefs, and Other Papers § 1.50 Specifications as to briefs. The...

  14. 47 CFR 1.50 - Specifications as to briefs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Specifications as to briefs. 1.50 Section 1.50 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure Pleadings, Briefs, and Other Papers § 1.50 Specifications as to briefs. The...

  15. 47 CFR 1.50 - Specifications as to briefs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Specifications as to briefs. 1.50 Section 1.50 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure Pleadings, Briefs, and Other Papers § 1.50 Specifications as to briefs. The...

  16. 47 CFR 1.50 - Specifications as to briefs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Specifications as to briefs. 1.50 Section 1.50 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure Pleadings, Briefs, and Other Papers § 1.50 Specifications as to briefs. The...

  17. 47 CFR 1.50 - Specifications as to briefs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Specifications as to briefs. 1.50 Section 1.50 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure Pleadings, Briefs, and Other Papers § 1.50 Specifications as to briefs. The...

  18. Cumulative index to NASA Tech Briefs, 1970-1975. [bibliographies

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Tech briefs of technology derived from the research and development activities of the National Aeronautics and Space Administration are presented. Abstracts and indexes of subject, personal author, originating center, and tech brief number for the 1970-1975 tech briefs are presented.

  19. 41 CFR 105-70.036 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Post-hearing briefs. 105... Administration 70-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.036 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a...

  20. 49 CFR 31.36 - Post-hearing briefs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Post-hearing briefs. 31.36 Section 31.36 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.36 Post-hearing briefs. The ALJ may require the parties to file post-hearing briefs. In any event, any party may file a...