#### Sample records for 4pm topics covered

1. Topics

ERIC Educational Resources Information Center

Mathematics Teaching, 1972

1972-01-01

Topics discussed in this column include patterns of inverse multipliers in modular arithmetic; diagrams for product sets, set intersection, and set union; function notation; patterns in the number of partitions of positive integers; and tessellations. (DT)

2. A Comparative Analysis of Questions in American, Singaporean, and Turkish Mathematics Textbooks Based on the Topics Covered in 8th Grade in Turkey

ERIC Educational Resources Information Center

Ozer, Eren; Sezer, Renan

2014-01-01

This study offers a comparative analysis of questions found in Turkish, Singaporean, and American mathematics textbooks and workbooks based on topics covered in the 8th grade mathematics curriculum in Turkey. To this end, the study utilizes the 3-dimensional framework developed by Li. When the questions in the textbooks and workbooks…

3. Pharmacokinetics and pharmacodynamics of methylprednisolone when administered at 8 am versus 4 pm

PubMed Central

Fisher, Lynn E.; Ludwig, Elizabeth A.; Wald, Jeffrey A.; Sloan, Rita R.; Middleton, Elliott; Jusko, William J.

2014-01-01

The temporal variations in the pharmacokinetics and pharmacodynamics of methylprednisolone at 8 am versus 4 pm were investigated in six healthy male volunteers. Subjects completed three phases: no drug administration, 20 mg intravenous methylprednisolone at 8 am, and the same dose at 4 pm. Methylprednisolone clearance was 28% greater in the afternoon. The suppressive effects of methylprednisolone on basophils (measured as whole blood histamine), helper T lymphocytes, and cortisol concentrations, assessed by the ratio of the area under the curve (AUC) after methylprednisolone to the baseline AUC, were not different between the phases. The 50% inhibitory concentration values for methylprednisolone derived from pharmacodynamic models were also similar, indicating no difference in intrinsic responsiveness. However, cortisol concentrations returned to baseline about 4 hours earlier after the 4 pm compared with the 8 AM dose because of the enhanced afternoon methylprednisolonc clearance. These findings are in agreement with other studies that suggest adequate clinical effects and less disturbance of cortisol circadian behavior when methylprednisolone is administered as a single dose in the morning. PMID:1535301

4. Simple, Scalable, Script-based, Science Processor for Measurements - Data Mining Edition (S4PM-DME)

Pham, L. B.; Eng, E. K.; Lynnes, C. S.; Berrick, S. W.; Vollmer, B. E.

2005-12-01

The S4PM-DME is the Goddard Earth Sciences Distributed Active Archive Center's (GES DAAC) web-based data mining environment. The S4PM-DME replaces the Near-line Archive Data Mining (NADM) system with a better web environment and a richer set of production rules. S4PM-DME enables registered users to submit and execute custom data mining algorithms. The S4PM-DME system uses the GES DAAC developed Simple Scalable Script-based Science Processor for Measurements (S4PM) to automate tasks and perform the actual data processing. A web interface allows the user to access the S4PM-DME system. The user first develops personalized data mining algorithm on his/her home platform and then uploads them to the S4PM-DME system. Algorithms in C and FORTRAN languages are currently supported. The user developed algorithm is automatically audited for any potential security problems before it is installed within the S4PM-DME system and made available to the user. Once the algorithm has been installed the user can promote the algorithm to the "operational" environment. From here the user can search and order the data available in the GES DAAC archive for his/her science algorithm. The user can also set up a processing subscription. The subscription will automatically process new data as it becomes available in the GES DAAC archive. The generated mined data products are then made available for FTP pickup. The benefits of using S4PM-DME are 1) to decrease the downloading time it typically takes a user to transfer the GES DAAC data to his/her system thus off-load the heavy network traffic, 2) to free-up the load on their system, and last 3) to utilize the rich and abundance ocean, atmosphere data from the MODIS and AIRS instruments available from the GES DAAC.

5. Riparian Land Use/Land Cover Data for Five Study Units in the Nutrient Enrichment Effects Topical Study of the National Water-Quality Assessment Program

USGS Publications Warehouse

Johnson, Michaela R.; Buell, Gary R.; Kim, Moon H.; Nardi, Mark R.

2007-01-01

This dataset was developed as part of the National Water-Quality Assessment (NAWQA) Program, Nutrient Enrichment Effects Topical (NEET) study for five study units distributed across the United States: Apalachicola-Chattahoochee-Flint River Basin, Central Columbia Plateau-Yakima River Basin, Central Nebraska Basins, Potomac River Basin and Delmarva Peninsula, and White, Great and Little Miami River Basins. One hundred forty-three stream reaches were examined as part of the NEET study conducted 2003-04. Stream segments, with lengths equal to the logarithm of the basin area, were delineated upstream from the downstream ends of the stream reaches with the use of digital orthophoto quarter quadrangles (DOQQ) or selected from the high-resolution National Hydrography Dataset (NHD). Use of the NHD was necessary when the stream was not distinguishable in the DOQQ because of dense tree canopy. The analysis area for each stream segment was defined by a buffer beginning at the segment extending to 250 meters lateral to the stream segment. Delineation of land use/land cover (LULC) map units within stream segment buffers was conducted using on-screen digitizing of riparian LULC classes interpreted from the DOQQ. LULC units were mapped using a classification strategy consisting of nine classes. National Wetlands Inventory (NWI) data were used to aid in wetland classification. Longitudinal transect sampling lines offset from the stream segments were generated and partitioned into the underlying LULC types. These longitudinal samples yielded the relative linear extent and sequence of each LULC type within the riparian zone at the segment scale. The resulting areal and linear LULC data filled in the spatial-scale gap between the 30-meter resolution of the National Land Cover Dataset and the reach-level habitat assessment data collected onsite routinely for NAWQA ecological sampling. The final data consisted of 12 geospatial datasets: LULC within 25 meters of the stream reach

6. Literature Review on Topics of Urgent RSA Needs and Concerns. (Covers Research Performed from October 1976 to June 1978.) Final Report.

ERIC Educational Resources Information Center

Pan, Elizabeth

Four state-of-the-art reports were prepared and disseminated in both printed and audio cassette forms to summarize the available knowledge in four areas of concern in the field of rehabilitation. Based on the recommendations of a consumer panel composed mainly of representatives from the intended audience, the topics of the reports and the authors…

7. Ciclopirox Topical

MedlinePlus

... ciclopirox topical solution.Ciclopirox topical solution may catch fire. Do not use this medication near heat or ... have ever had any disease that affects your immune system, such as human immunodeficiency virus (HIV) or ...

8. Testosterone Topical

MedlinePlus

... in which the body does not produce enough natural testosterone). Testosterone is used only for men with ... topical may control your symptoms but will not cure your condition. Continue to use testosterone topical even ...

9. Desonide Topical

MedlinePlus

... cover the area with tight fitting diapers or plastic pants.Do not wrap or bandage the treated ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap® or Handi-Wrap®). ...

10. Desoximetasone Topical

MedlinePlus

... cover the area with tight fitting diapers or plastic pants.Do not wrap or bandage the treated ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap® or Handi-Wrap®). ...

11. Topics for Mathematics Clubs.

ERIC Educational Resources Information Center

Dalton, LeRoy C., Ed.; Snyder, Henry D., Ed.

The ten chapters in this booklet cover topics not ordinarily discussed in the classroom: Fibonacci sequences, projective geometry, groups, infinity and transfinite numbers, Pascal's Triangle, topology, experiments with natural numbers, non-Euclidean geometries, Boolean algebras, and the imaginary and the infinite in geometry. Each chapter is…

MedlinePlus

... a medication that is applied topically to the vagina. Estradiol is in a class of medications called ... swelling, redness, burning, irritation, or itching of the vagina vaginal discharge Some side effects can be serious. ...

13. Mometasone Topical

MedlinePlus

Mometasone comes as a topical cream, ointment, and lotion. It usually is applied externally once a day. ... affected skin areas once daily.To apply the lotion, place a few drops on the affected areas ...

14. Fluorouracil Topical

MedlinePlus

... caused by years of too much exposure to sunlight). Fluorouracil cream and topical solution are also used ... plan to avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and ...

15. Bexarotene Topical

MedlinePlus

... talking to your doctor.Bexarotene gel may catch fire. Do not use this medication near a source ... sunlamps and to wear protective clothing, sunglasses, and sunscreen. Topical bexarotene may make your skin sensitive to ...

16. Fluorouracil Topical

MedlinePlus

... topical solution are used to treat actinic or solar keratoses (scaly or crusted lesions [skin areas] caused ... you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the ...

17. Spotlight Topics

A Spotlight Topic consists of a set of two or more review articles focused on a specific subject in surface science. The topics are recommended by the Board of Editors. A topic may be chosen because it is particularly new or fast-breaking, thus deserving introduction to the general readership. Or, it may be because a topic is especially controversial or confusing, requiring clarification by experts. Each review will give a critical assessment rather than an encyclopedic report. While our editors always will insist on fairness and accuracy, any review which forwards an opinion is bound to be somewhat subjective. Therefore, it is the editors' wish that the set of reviews written by different authors on the same subject matter will provide a broad and balanced viewpoint. It is often the case that an author who is an expert in a technique or method may be especially enthusiastic or critical about this technique or method. A companion review in the set may provide a different viewpoint. We are hopeful that the reader, after studying these reviews and checking some of the key references, will obtain an informed opinion of the subject. We think the set of reviews in a spotlight area will considerably shorten the ``learning time'' that a nonexpert would otherwise need to become knowledgeable about a subject. In this issue, we feature a spotlight topic on oxide surfaces. The set contains an overview article by Jacques Jupille, and four articles written by G. Pacchioni, F. Cosandey and T. E. Madey, B. G. Daniels, R. Lindsay and G. Thornton, and C. Noguera respectively. Of these, the article by Pacchioni has already appeared in SRL 7, 277 (2000). The other three articles appear in this issue. A reader who wishes to suggest a spotlight topic or recommend authors to write such reviews should contact the Editor-in-Chief. We would like to hear from you.

18. Diflorasone Topical

MedlinePlus

... area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.Do ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap). ...

19. Fluocinonide Topical

MedlinePlus

... area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.Do ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap). ...

20. Triamcinolone Topical

MedlinePlus

... area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.If ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap). ...

1. Hydrocortisone Topical

MedlinePlus

... area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.Do ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap). ...

2. Halcinonide Topical

MedlinePlus

... area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.Do ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap). ...

3. Betamethasone Topical

MedlinePlus

... area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.Do ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap.) ...

4. Fluocinolone Topical

MedlinePlus

... area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.Do ... into the affected areas. Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap). ...

5. Topical anesthesia.

PubMed

Kumar, Mritunjay; Chawla, Rajiv; Goyal, Manish

2015-01-01

Topical anesthetics are being widely used in numerous medical and surgical sub-specialties such as anesthesia, ophthalmology, otorhinolaryngology, dentistry, urology, and aesthetic surgery. They cause superficial loss of pain sensation after direct application. Their delivery and effectiveness can be enhanced by using free bases; by increasing the drug concentration, lowering the melting point; by using physical and chemical permeation enhancers and lipid delivery vesicles. Various topical anesthetic agents available for use are eutectic mixture of local anesthetics, ELA-max, lidocaine, epinephrine, tetracaine, bupivanor, 4% tetracaine, benzocaine, proparacaine, Betacaine-LA, topicaine, lidoderm, S-caine patch™ and local anesthetic peel. While using them, careful attention must be paid to their pharmacology, area and duration of application, age and weight of the patients and possible side-effects. PMID:26702198

6. Topical anesthesia

PubMed Central

Kumar, Mritunjay; Chawla, Rajiv; Goyal, Manish

2015-01-01

Topical anesthetics are being widely used in numerous medical and surgical sub-specialties such as anesthesia, ophthalmology, otorhinolaryngology, dentistry, urology, and aesthetic surgery. They cause superficial loss of pain sensation after direct application. Their delivery and effectiveness can be enhanced by using free bases; by increasing the drug concentration, lowering the melting point; by using physical and chemical permeation enhancers and lipid delivery vesicles. Various topical anesthetic agents available for use are eutectic mixture of local anesthetics, ELA-max, lidocaine, epinephrine, tetracaine, bupivanor, 4% tetracaine, benzocaine, proparacaine, Betacaine-LA, topicaine, lidoderm, S-caine patch™ and local anesthetic peel. While using them, careful attention must be paid to their pharmacology, area and duration of application, age and weight of the patients and possible side-effects. PMID:26702198

MedlinePlus

... of the hair to cover all of the hair on your head. Keep the suspension on your hair and scalp ... share combs, brushes, towels, pillows, hats, scarves, or hair accessories. Be sure to check everyone in your immediate family for head lice if another family member is being treated ...

8. Topical Steroids.

PubMed

Oakley, Gretchen M; Harvey, Richard J

2016-01-01

Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory condition with heterogeneous pathophysiology. A cornerstone of the management of this condition is the use of anti-inflammatory agents. Corticosteroids are very effective and the most commonly used, but other drugs with immunodulatory activity such as anti-IL5, doxycycline (Th2), and macrolides (anti-neutrophilic/IL8) have been shown to have efficacy. Although systemic corticosteroids have shown benefit in managing this condition, the frequency of use often required in this condition is associated with significant adverse effects. Topical corticosteroids, particularly when utilized after endoscopic sinus surgery and delivered in a high volume, high pressure manner, provide the desired anti-inflammatory effects with nearly negligible systemic absorption. Studies assessing the long-term use of second generation topical corticosteroids have demonstrated no significant effects on cortisol levels, growth rate, intraocular pressures or lens opacification, or local mucosal atrophy. Patients who often respond most favorably to corticosteroid treatment are those with a Th2-mediated, highly eosinophilic CRSwNP. However, there is a subset of patients who are steroid resistant. In the case of a predominantly neutrophilic CRSwNP, it is important to be aware that patients may respond well to the use of macrolide therapy. Additionally, the use of verapamil has shown promise in increasing steroid responsiveness in a difficult to treat group of patients with steroid resistance. Topical corticosteroids play a key role in the long term management of this complicated inflammatory condition by providing the much needed pharmacologic local control with minimal systemic adverse effects. PMID:27466854

9. [Topical contraceptives].

PubMed

Alipov, V I; Korkhov, V V

1982-02-01

Recently there has been little interest in topical contraceptives. The most popular are the cervical cap and the diaphragm. Other types of mechanical contraceptive devices are being investigated. Standley and Kessler have developed a device for introduction into the cervical canal with a reservoir of spermatocide, it does not block the flow of blood during menstruation. New models of vaginal rings are also being developed which are simple enough for self-insertion and also contain a reservoir of spermatocide. Work is being done on spermatocide-containing sponges in many countries. Another project being investigated is the possibility of using natural proteins, collagens, and other substances which absorb spermatozoids. The ancients used various vaginal suppositories to kill spermatozoids; in the late 19th century quinine sulfate was used for this, and a variety of substances have been used recently. These spermicidal creams also have the advantage of acting as anti-infectious agents in many cases. But they do have some negative effects. They are about 85% effective, are local irritants, and some cause discomfort during intercourse. And it is possible that some are resorbed by the body and act on the liver and other organs. Vaginal globules and suppositories are also popular. The "Kontraceptin-T" brand contains quinosol, boric acid, and tannin. There are also foaming tablets which are mixed with water and then introduced. New locally-active chemical substances are being developed in Japan, West Germany, and the USSR. Kontraceptin-E contains paranonyl-phenoxypolyethylene glycol and sodium dioctylsulfosuccinate. The "Norforks" and other preparations contain mercurial compounds which may turn out to be harmful. The future promises the development of products which will act to prevent fertilization by acting on the hyaluronidase and the acrosine of the spermatozoid, thus preventing it from penetrating the ovum. It would be best to find enzyme inhibitors which are

10. Covering Politics.

ERIC Educational Resources Information Center

Gruber, Ryan; Wind, Andrew; Trevidi, Neema

2000-01-01

Presents four articles considering: (1) the media's role in the coverage of politics; (2) the influence of photography particularly in terms of the president; (3) an event where an Iowa student had a chance to work with professionals while covering politics; and (4) considering scholastic reporters covering national candidates as they learn and…

11. Sky cover

Gerth, Jordan J.

Of all of the standard meteorological parameters collected and observed daily, sky cover is not only one of the most complex, but the one that is fairly ambiguously defined and difficult to quantify. Despite that, the implications of how cloud fraction and sky cover are understood not only impact daily weather forecasts, but also present challenges to assessing the state of the earth's climate system. Part of the reason for this is the lack of observational methods for verifying the skill of clouds represented and parameterized in numerical models. While human observers record sky cover as part of routine duties, the spatial coverage of such observations in the United States is relatively sparse. There is greater spatial coverage of automated observations, and essentially complete coverage from geostationary weather satellites that observe the Americas. A good analysis of sky cover reconciles differences between manual observations, automated observations, and satellite observations, through an algorithm that accounts for the strengths and weaknesses of each dataset. This work describes the decision structure for trusting and weighting these similar observations. Some of the issues addressed include: human and instrument error resulting from approximations and estimations, a deficiency in high cloud detectability using surface-based ceilometers, poorly resolved low cloud using infrared channels on space-based radiometers during overnight hours, and decreased confidence in satellite-detected cloud during stray light periods. Using the blended sky cover analysis as the best representation of cloudiness, it is possible to compare the analysis to numerical model fields in order to assess the performance of the model and the parameterizations therein, as well as confirm or uncover additional relationships between sky cover and pertinent fields using an optimization methodology. The optimizer minimizes an affine expression of adjusted fields to the "truth" sky cover

12. Cover Crops

Technology Transfer Automated Retrieval System (TEKTRAN)

Cover crops are great tools to improve soil quality and health, and great tools to increase carbon sequestration. They are nutrient management tools that can help scavenge nitrate, cycle nitrogen to the following crop, mine NO3 from groundwater, and increase nitrogen use efficiency of cropping syste...

13. Wall Covering

NASA Technical Reports Server (NTRS)

1978-01-01

The attractive wall covering shown below is one of 132 styles in the Mirror Magic II line offered by The General Tire & Rubber Company, Akron, Ohio. The material is metallized plastic fabric, a spinoff from space programs. Wall coverings are one of many consumer applications of aluminized plastic film technology developed for NASA by a firm later bought by King-Seeley Thermos Company, Winchester, Massachusetts, which now produces the material. The original NASA use was in the Echo 1 passive communications satellite, a "space baloon" made of aluminized mylar; the high reflectivity of the metallized coating enabled relay of communications signals from one Earth station to another by "bouncing" them off the satellite. The reflectivity feature also made the material an extremely efficient insulator and it was subsequently widely used in the Apollo program for such purposes as temperature control of spacecraft components and insulation of tanks for fuels that must be maintained at very low temperatures. I Used as a wall covering, the aluminized material offers extra insulation, reflects light and I resists cracking. In addition to General Tire, King-Seeley also supplies wall covering material to Columbus Coated Fabrics Division of Borden, Incorporated, Columbus, Ohio, among others.

14. Hot topics from the Tevatron

SciTech Connect

Glenzinski, D.; /Fermilab

2008-01-01

The Tevatron Run-II began in March 2001. To date, both the CDF and D0 experiments have collected 1 fb{sup -1} of data each. The results obtained from this data set were summarized at this conference in 39 parallel session presentations covering a wide range of topics. The author summarizes the most important of those results here and comments on some of the prospects for the future.

15. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

Bozic, Mirjana; Man'ko, Margarita

2009-09-01

Sascha Wallentowitz), 2004 (Trieste, Italy, by Naseem Rahman and Sascha Wallentowitz), 2005 (Bilkent, Ankara, by Alexander Shumovsky), 2006 (Vienna, by Helmut Rauch), 2007 (Palermo, Italy, by Antonino Messina) and 2008 (Belgrade, by Mirjana Bozic). The CEWQO series developed in two directions following the rapid development of quantum optics and the transitional development of the scientific collaboration of Central European researchers with researchers from old and new emerging Central European countries, and from all over the world. The topics discussed at CEWQO 08 were divided into ten groups that aimed to cover the broad scope of modern quantum optics: Fundamental aspects of quantum optics and quantum mechanics Single photons and photon pairs Cavity and circuit QED Atoms in intense fields Neutron, atom and molecular quantum optics Quantum gases and fluids Coherence, entanglement and decoherence Optical properties of condensed matter and nanostructures Open quantum systems and chaos Quantum information processing Central European Workshops on Quantum Optics realize and are consistent with a wider idea, and a social, economical, cultural and political program promoted since 1989 by the Central European Initiative (CEI), the main goal of which was to help transition countries in Central Europe to become closer to the EU. The resulting support of the CEI, first obtained thanks to the scientific reputation, organizing activities, and efforts of Helmut Rauch, has been very important for the organization of the CEWQO in recent years, particularly in 2008. The support of the Sixth and Seventh Framework Programs of the European Commission was also very important. A short review of papers in this topical issue A principal role in this topical issue is played by the photon. Vuletic et al describe the mapping of the photon-polarization state onto a single collective-spin excitation (magnon) shared between two atomic ensembles. A heralded quantum memory based on this mapping is

16. Evapotranspiration (ET) covers.

PubMed

Rock, Steve; Myers, Bill; Fiedler, Linda

2012-01-01

about specific projects using ET covers. There are three general approaches for non-conventional cover systems to achieve approval for installation; the first is when equivalent performance to conventional final cover systems can be demonstrated directly on site. This is the approach used by the Sandia study, by most ACAP sites, and the Rocky Mountain Arsenal. A second approach is used when there are data from a site specific study such as an ACAP installation at a site that has analogous soil and climate conditions. Several sites in Colorado and Southern California have achieved approval based on data from similar sites. The third most common approach for regulatory approval is by installation of data collection systems with the agreement that the permanence of the ET cover installation is contingent on success of the cover in meeting certain performance goals. This article is intended as an introduction to the topic and is not intended to serve as guidance for design or construction, nor indicate the appropriateness of using an ET cover systems at a particular site. PMID:22574378

17. Cover Picture.

PubMed

Krömer; Rios-Carreras; Fuhrmann; Musch; Wunderlin; Debaerdemaeker; Mena-Osteritz; Bäuerle

2000-10-01

The cover picture shows the synthesis of novel conjugated macrocycles assembled from oligothiophenes bearing terminal acetylene groups. Under pseudo-high-dilution conditions the oxidative cyclooligomerization first gives the oligothiophenediynes, the precursors to the new class of alpha-cyclo[n]thiophenes. The detailed structure of macrocycles with up to 76 ring members and cavities of up to 3 nm could be investigated by means of X-ray structure analysis, scanning tunneling microscopy, and quantum chemical calculations (see the molecular model top right). The novel rings combine the excellent electronic properties of the corresponding linearly conjugated oligomers with the possibility of complexing large organic guest molecules or other objects (the tower of the Cathedral at Ulm represents a nanometer-sized, rodlike entity), which should have new fundamental properties and applications. The background shows the image obtained by scanning electron microscopy of a self-assembled and perfectly ordered monolayer of macrocycles on a graphite surface. More on these fascinating nanometer-sized rings can be found in the communication by P. Bäuerle et al. on p. 3481 ff. PMID:11091367

18. Freshman Health Topics

ERIC Educational Resources Information Center

Hovde, Karen

2011-01-01

This article examines a cluster of health topics that are frequently selected by students in lower division classes. Topics address issues relating to addictive substances, including alcohol and tobacco, eating disorders, obesity, and dieting. Analysis of the topics examines their interrelationships and organization in the reference literature.…

19. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

Bozic, Mirjana; Man'ko, Margarita

2009-09-01

Sascha Wallentowitz), 2004 (Trieste, Italy, by Naseem Rahman and Sascha Wallentowitz), 2005 (Bilkent, Ankara, by Alexander Shumovsky), 2006 (Vienna, by Helmut Rauch), 2007 (Palermo, Italy, by Antonino Messina) and 2008 (Belgrade, by Mirjana Bozic). The CEWQO series developed in two directions following the rapid development of quantum optics and the transitional development of the scientific collaboration of Central European researchers with researchers from old and new emerging Central European countries, and from all over the world. The topics discussed at CEWQO 08 were divided into ten groups that aimed to cover the broad scope of modern quantum optics: Fundamental aspects of quantum optics and quantum mechanics Single photons and photon pairs Cavity and circuit QED Atoms in intense fields Neutron, atom and molecular quantum optics Quantum gases and fluids Coherence, entanglement and decoherence Optical properties of condensed matter and nanostructures Open quantum systems and chaos Quantum information processing Central European Workshops on Quantum Optics realize and are consistent with a wider idea, and a social, economical, cultural and political program promoted since 1989 by the Central European Initiative (CEI), the main goal of which was to help transition countries in Central Europe to become closer to the EU. The resulting support of the CEI, first obtained thanks to the scientific reputation, organizing activities, and efforts of Helmut Rauch, has been very important for the organization of the CEWQO in recent years, particularly in 2008. The support of the Sixth and Seventh Framework Programs of the European Commission was also very important. A short review of papers in this topical issue A principal role in this topical issue is played by the photon. Vuletic et al describe the mapping of the photon-polarization state onto a single collective-spin excitation (magnon) shared between two atomic ensembles. A heralded quantum memory based on this mapping is

20. Salicylic Acid Topical

MedlinePlus

Propa pH® Peel-Off Acne Mask ... pimples and skin blemishes in people who have acne. Topical salicylic acid is also used to treat ... medications called keratolytic agents. Topical salicylic acid treats acne by reducing swelling and redness and unplugging blocked ...

1. Health Topic XML File Description

MedlinePlus

... has its own topic> element. This topic title is the value of the element. The attributes ... topic pages and other pages. Example: topic title="Abdominal Pain" url="https://www.nlm.nih.gov/ ...

2. Finding scientific topics

PubMed Central

Griffiths, Thomas L.; Steyvers, Mark

2004-01-01

A first step in identifying the content of a document is determining which topics that document addresses. We describe a generative model for documents, introduced by Blei, Ng, and Jordan [Blei, D. M., Ng, A. Y. & Jordan, M. I. (2003) J. Machine Learn. Res. 3, 993-1022], in which each document is generated by choosing a distribution over topics and then choosing each word in the document from a topic selected according to this distribution. We then present a Markov chain Monte Carlo algorithm for inference in this model. We use this algorithm to analyze abstracts from PNAS by using Bayesian model selection to establish the number of topics. We show that the extracted topics capture meaningful structure in the data, consistent with the class designations provided by the authors of the articles, and outline further applications of this analysis, including identifying “hot topics” by examining temporal dynamics and tagging abstracts to illustrate semantic content. PMID:14872004

3. Topical diclofenac solution.

PubMed

Moen, Marit D

2009-01-01

Topical diclofenac solution (Pennsaid) is a liquid formulation containing the NSAID diclofenac sodium (1.5% w/w). The solution base contains 45% w/w dimethyl sulfoxide (DMSO) to enhance the absorption of diclofenac through the skin. Topical diclofenac solution is applied directly to the knee for treatment of symptoms associated with osteoarthritis of the knee. In well designed 4- to 12-week trials in patients with primary osteoarthritis of the knee, topical diclofenac solution (40 drops four times daily) was significantly more effective than placebo or vehicle control (carrier solution without diclofenac) for improving Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index pain and physical function, and improving patient global assessment (PGA) and/or patient overall health assessment scores from baseline to the final assessments. Topical diclofenac solution (50 drops three times daily) was as effective as oral diclofenac 150 mg/day for improving WOMAC pain and physical function and PGA scores in a 12-week double-blind study in patients with osteoarthritis of the knee. Topical diclofenac solution was generally well tolerated. The most common treatment-emergent adverse event experienced by topical diclofenac solution recipients was dry skin at the application site. Gastrointestinal adverse events and abnormal laboratory parameters were less common with topical diclofenac solution than with oral diclofenac. PMID:19943711

4. SETI: A good introductory physics topic

Hobson, Art

1997-04-01

If America is to achieve the science literacy that is essential to industrialized democracy, all students must study such topics as scientific methodology, pseudoscience, ozone depletion, and global warming. My large-enrollment liberal-arts physics course covers the great principles of physics along with several such philosophical and societal topics. It is easy to include the interdisciplinary context of physics in courses for non-scientists, because these courses are flexible, conceptual, and taught to students whose interests span a broad range. Students find these topics relevant and fascinating, leading to large enrollments by non-scientists even in courses labeled ''physics.'' I will discuss my approach to teaching the search for extra-terrestrial intelligence (SETI), a topic with lots of good physics and with connections to scientific methodology and pseudoscience. A textbook for this kind of course has been published, Physics: Concepts and Connections (Prentice-Hall, 1995).

5. Women's Health Topics

MedlinePlus

... Women's Health 10903 New Hampshire Avenue WO32-2333 Silver Spring, MD 20993 More in Women's Health Topics ... Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20993 1-888-INFO-FDA (1- ...

6. Diclofenac Topical (osteoarthritis pain)

MedlinePlus

... growths on the skin caused by too much sun exposure). This monograph only gives information about diclofenac gel ( ... you should know that you should not apply sunscreens, cosmetics, lotions, moisturizers, insect repellents, or other topical ...

7. TOPICAL TREATMENT OF MELASMA

PubMed Central

2009-01-01

Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. The management of melasma is challenging and requires a long-term treatment plan. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. Multiple options for topical treatment are available, of which hydroquinone (HQ) is the most commonly prescribed agent. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma. PMID:20101327

8. IP Internal Movement and Topicalization

ERIC Educational Resources Information Center

Kuo, Pei-Jung

2009-01-01

In this dissertation, I investigate the phenomenon of internal topicalization cross-linguistically, using Chinese as a starting point. Internal topicalization refers to constructions in which a topic phrase is placed between the subject and the verb (in contrast to external topicalization, which involves a topic in the CP domain). I argue that…

9. Topical antibiotics in dermatology.

PubMed

Hirschmann, J V

1988-11-01

Topical antibiotics are safe and effective in certain conditions, primarily acne, rosacea, and nasal carriage of Staphylococcus aureus. They are useful in impetigo only when it is of limited extent. Their efficacy in other pyodermas is unclear, although mupirocin is probably effective in many cases. In "infected eczema" that does not require systemic therapy they seem to add little to what topical corticosteroids alone achieve. They are ineffective in reducing the incidence of significant infection with indwelling intravenous catheters. They are safe preparations, but extensive use, especially in closed populations, may encourage the emergence of resistant bacteria. PMID:2972259

10. Topical Therapies for Pruritus

PubMed Central

Elmariah, Sarina B.; Lerner, Ethan A.

2011-01-01

Itch, or pruritus, is the predominant symptom associated with acute and chronic cutaneous disease and in some cases, may be debilitating. To date, there is no single universally effective anti-itch treatment. As the pathophysiology of itch in most cutaneous or systemic disorders remains unclear, anti-pruritic therapy is often directed against a variety of targets, including the epidermal barrier, immune system, or the nervous system. Topical therapy is the mainstay of dermatologic management of acute or localized itch or in patients with contraindications to systemic therapies. This review will summarize current topical therapies to treat pruritus and discuss potential future therapies. PMID:21767774

11. Historical Topics in Algebra.

ERIC Educational Resources Information Center

National Council of Teachers of Mathematics, Inc., Reston, VA.

This is a reprint of the historical capsules dealing with algebra from the 31st Yearbook of NCTM,"Historical Topics for the Mathematics Classroom." Included are such themes as the change from a geometric to an algebraic solution of problems, the development of algebraic symbolism, the algebraic contributions of different countries, the origin and…

12. Housing: Topic Paper F.

ERIC Educational Resources Information Center

National Council on the Handicapped, Washington, DC.

This paper, one of a series of topic papers assessing federal laws and programs affecting persons with disabilities, addresses the issue of housing. Major federal responsibilities are to develop additional housing opportunities for persons with disabilities and to assure that currently available housing is equally open to individuals with…

13. Topic: Mastery Learning.

ERIC Educational Resources Information Center

Killoran, James, Ed.

1983-01-01

This journal issue addresses the topic of mastery learning at both the elementary and secondary school levels. The first article, "The Theory and Practice of Mastery Learning" (Guskey), gives a definition of and information about the development, operation, and application of mastery learning, based on the theories of Benjamin Bloom. In addition,…

14. Differential Topic Models.

PubMed

Chen, Changyou; Buntine, Wray; Ding, Nan; Xie, Lexing; Du, Lan

2015-02-01

In applications we may want to compare different document collections: they could have shared content but also different and unique aspects in particular collections. This task has been called comparative text mining or cross-collection modeling. We present a differential topic model for this application that models both topic differences and similarities. For this we use hierarchical Bayesian nonparametric models. Moreover, we found it was important to properly model power-law phenomena in topic-word distributions and thus we used the full Pitman-Yor process rather than just a Dirichlet process. Furthermore, we propose the transformed Pitman-Yor process (TPYP) to incorporate prior knowledge such as vocabulary variations in different collections into the model. To deal with the non-conjugate issue between model prior and likelihood in the TPYP, we thus propose an efficient sampling algorithm using a data augmentation technique based on the multinomial theorem. Experimental results show the model discovers interesting aspects of different collections. We also show the proposed MCMC based algorithm achieves a dramatically reduced test perplexity compared to some existing topic models. Finally, we show our model outperforms the state-of-the-art for document classification/ideology prediction on a number of text collections. PMID:26353238

15. Topical Research: Africa.

ERIC Educational Resources Information Center

Lynn, Karen

This lesson plan can be used in social studies, language arts, or library research. The instructional objective is for students to select a topic of study relating to Africa, write a thesis statement, collect information from media sources, and develop a conclusion. The teacher may assign the lesson for written or oral evaluation. The teacher…

16. Topical delivery of hexamidine.

PubMed

Parisi, Nicola; Paz-Alvarez, Miguel; Matts, Paul J; Lever, Rebecca; Hadgraft, Jonathan; Lane, Majella E

2016-06-15

Hexamidine diisethionate (HEX D) has been used for its biocidal actions in topical preparations since the 1950s. Recent data also suggest that it plays a beneficial role in skin homeostasis. To date, the extent to which this compound penetrates the epidermis has not been reported nor how its topical delivery may be modulated. In the present work we set out to characterise the interaction of HEX D with the skin and to develop a range of simple formulations for topical targeting of the active. A further objective was to compare the skin penetration of HEX D with its corresponding dihydrochloride salt (HEX H) as the latter has more favourable physicochemical properties for skin uptake. Candidate vehicles were evaluated by in vitro Franz cell permeation studies using porcine skin. Initially, neat solvents were investigated and subsequently binary systems were examined. The solvents and chemical penetration enhancers investigated included glycerol, dimethyl isosorbide (DMI), isopropyl alcohol (IPA), 1,2-pentanol (1,2-PENT), polyethylene glycol (PEG) 200, propylene glycol (PG), propylene glycol monolaurate (PGML) and Transcutol(®)P (TC). Of a total of 30 binary solvent systems evaluated only 10 delivered higher amounts of active into the skin compared with the neat solvents. In terms of topical efficacy, formulations containing PGML far surpassed all other solvents or binary combinations. More than 70% of HEX H was extracted from the skin following application in PG:PGML (50:50). Interestingly, the same vehicle effectively promoted skin penetration of HEX D but demonstrated significantly lower uptake into and through the skin (30%). The findings confirm the unpredictable nature of excipients on delivery of actives with reference to skin even where there are minor differences in molecular structures. We also believe that they underline the ongoing necessity for fundamental studies on the interaction of topical excipients with the skin. PMID:27130367

17. Estimating Cloud Cover

ERIC Educational Resources Information Center

Moseley, Christine

2007-01-01

The purpose of this activity was to help students understand the percentage of cloud cover and make more accurate cloud cover observations. Students estimated the percentage of cloud cover represented by simulated clouds and assigned a cloud cover classification to those simulations. (Contains 2 notes and 3 tables.)

18. Topical retinoids for acne.

PubMed

Yeh, Lindsey; Bonati, Lauren Meshkov; Silverberg, Nanette B

2016-06-01

Topical retinoids are currently approved by the US Food and Drug Administration for the treatment of acne vulgaris in nonpregnant, nonlactating patients 12 years of age and older. Their efficacy, safety, and tolerability are well documented for inflammatory and noninflammatory acne with studies repeatedly demonstrating a decrease in the number of lesions, significant improvement in acne severity, improvement in the cosmetic appearance of acne, and the prevention of acne lesions through microcomedone formation. There is some variability between prescription retinoid products regarding efficacy, safety, and tolerability; with erythema, peeling, and dryness being common, potential side effects. Due to their efficacious and safe profile, topical retinoids remain the first-line treatment for acne vulgaris. PMID:27416308

19. Multiple layer insulation cover

DOEpatents

Farrell, James J.; Donohoe, Anthony J.

1981-11-03

A multiple layer insulation cover for preventing heat loss in, for example, a greenhouse, is disclosed. The cover is comprised of spaced layers of thin foil covered fabric separated from each other by air spaces. The spacing is accomplished by the inflation of spaced air bladders which are integrally formed in the cover and to which the layers of the cover are secured. The bladders are inflated after the cover has been deployed in its intended use to separate the layers of the foil material. The sizes of the material layers are selected to compensate for sagging across the width of the cover so that the desired spacing is uniformly maintained when the cover has been deployed. The bladders are deflated as the cover is stored thereby expediting the storage process and reducing the amount of storage space required.

MedlinePlus

... What's this? Submit Button Past Newsletters Cover Your Cough Language: English EspaÃ±ol Recommend on Facebook Tweet ... Posters only available as PDF files. Cover Your Cough, Flyer for Health Care Settings English [324 KB] ...

1. Cover crops for Alabama

Technology Transfer Automated Retrieval System (TEKTRAN)

Cover crops are grown to benefit the following crop as well as to improve the soil, but they are normally not intended for harvest. Selecting the right cover crops for farming operations can improve yields, soil and water conservation and quality, and economic productivity. Properly managed cover ...

2. Cover Crop Management

Technology Transfer Automated Retrieval System (TEKTRAN)

The potential benefits of cover crops in vegetable production systems depend on the type of cover crop that is used and how it is managed from planting to termination date. This chapter focuses on management practices that are applicable to a broad range cover crops and vegetable production systems ...

3. Topics in theoretical surface science

SciTech Connect

Todd, R.

1991-10-25

The energetics and structures of clean and adsorbate covered surfaces are investigated in this dissertation. First, the formalism, within the Corrected Effective Medium (CEM) method, for calculating the surface energy of a clean surface is derived. The surface energies for many different metals and their low index surfaces are presented. The minimization of the surface energy is then used to predict the multilayer relaxation of the Al(111), (100), Ni(100), (110) and Fe(100) surfaces. Extensions of the surface CEM formalism to calculate the binding energies of ordered adsorbates on metals surfaces are also derived. The minimization of the binding energy allowed determination of the binding heights, sites and the extent of induced multilayer relaxation for H and N atoms on the Fe(110), (100) and W(110) surfaces. The last topic deals with the dynamics of the epitaxial growth of metals on metal surfaces. The CEM method was first modified by making approximations to enable faster evaluations of the potential and its corresponding forces for molecular dynamics simulations. The goal of these simulations was to identify the important steps in the formation of equilibrium epitaxial structures. 180 refs., 31 figs., 18 tabs.

4. Symbiosis: Rich, Exciting, Neglected Topic

ERIC Educational Resources Information Center

Rowland, Jane Thomas

1974-01-01

Argues that the topic of symbiosis has been greatly neglected and underemphasized in general-biology textbooks. Discusses many types and examples of symbiosis, and provides an extensive bibliography of the literature related to this topic. (JR)

5. Incorporating Women and Crime Topics into Criminology Classes: Assignments, Exercises, and Projects.

ERIC Educational Resources Information Center

Wright, Richard A.

1987-01-01

Recommends a variety of books, assignments, exercises, and projects which can be incorporated into introductory criminology classes to compensate for the omission of topics on women and crime in textbooks and curricula. Includes a list of potential topics for writing assignments and a selection of films covering such topics as sexual harassment,…

6. Tamper resistant choke cover

SciTech Connect

Kneipkamp, L.E.

1981-12-29

A carburetor improvement is described for inhibiting tampering with a thermostatic choke coil after carburetor manufacture. A cover (3) fits over a choke coil housing (H) to enclose a choke lever, the thermostatic coil being mounted inside the cover. The cover has a circumferential flange (5) which abuts the outer surface of the housing, the flange having a notch (9) formed therein and the cover being rotatable about the outer surface of the housing to position one end of the coil relative to the choke lever. A retainer (7) locks the cover in a fixed position once the one end of the coil is located with respect to the choke lever. The retainer has a tab (11) insertable in the notch to prevent further rotation of the cover. A screw (15) having a detachable head (17) unremovably secures the retainer to the carburetor whereby once the retainer is secured, further movement of the cover is prevented.

7. Hypersensitivity to topical corticosteroids.

PubMed

Wilkinson, S M

1994-01-01

Contact hypersensitivity from topical corticosteroids is becoming increasingly recognized; it is present in 2-5% of the patients attending contact dermatitis clinics. The use of a corticosteroid series containing tixocortal pivalate 1% (petrolatum), to detect hypersensitivity to hydrocortisone, and other steroids 1% (ethanol), depending on local corticosteroid usage, detects the majority of cases of corticosteroid hypersensitivity. In selected cases, the use of intradermal tests further improves the diagnosis of corticosteroid hypersensitivity. Corticosteroid hypersensitivity occurs most frequently among patients with stasis dermatitis. However, corticosteroid hypersensitivity is also common in other types of dermatitis, occurring as frequently as hypersensitivity to several allergens (e.g. wool alcohols and colophony) in the European standard battery. Although hypersensitivity has mainly been reported with corticosteroids applied to the skin, reactions may also occur on mucosal surfaces, following systemic administration and with sex steroids. PMID:8313630

8. Current topics on sonoelectrochemistry.

PubMed

González-García, José; Esclapez, María Deseada; Bonete, Pedro; Hernández, Yolanda Vargas; Garretón, Luís Gaete; Sáez, Verónica

2010-02-01

Sonoelectrochemistry is undergoing a reemerging activity in the last years with an increasing number of papers appearing in a wide range of peer review journals. Applied studies which cover environmental treatments, synthesis or characterization of nanostructures, polymeric materials synthesis, analytical procedures, films preparations, membrane preparations among other interesting applications have been reviewed. The revised fundamental analyses trying to elucidate the mechanism of the interactions between the ultrasound and electrical fields, are focused on test electrochemical processes, on the use of unconventional solvents and combination with other techniques. After the review of the achievements and faults of sonoelectrochemistry, future research lines are suggested. PMID:19853270

9. Topical antimicrobials for burn wound infections.

PubMed

Dai, T; Huang, Y Y; Sharma, S K; Hashmi, J T; Kurup, D B; Hamblin, M R

2010-06-01

Throughout most of history, serious burns occupying a large percentage of body surface area were an almost certain death sentence because of subsequent infection. A number of factors such as disruption of the skin barrier, ready availability of bacterial nutrients in the burn milieu, destruction of the vascular supply to the burned skin, and systemic disturbances lead to immunosuppression combined together to make burns particularly susceptible to infection. In the 20th century the introduction of antibiotic and antifungal drugs, the use of topical antimicrobials that could be applied to burns, and widespread adoption of early excision and grafting all helped to dramatically increase survival. However the relentless increase in microbial resistance to antibiotics and other antimicrobials has led to a renewed search for alternative approaches to prevent and combat burn infections. This review will cover patented strategies that have been issued or filed with regard to new topical agents, preparations, and methods of combating burn infections. Animal models that are used in preclinical studies are discussed. Various silver preparations (nanocrystalline and slow release) are the mainstay of many approaches but antimicrobial peptides, topical photodynamic therapy, chitosan preparations, new iodine delivery formulations, phage therapy and natural products such as honey and essential oils have all been tested. This active area of research will continue to provide new topical antimicrobials for burns that will battle against growing multidrug resistance. PMID:20429870

10. Topical Antimicrobials for Burn Wound Infections

PubMed Central

Dai, Tianhong; Huang, Ying-Ying; Sharma, Sulbha K.; Hashmi, Javad T.; Kurup, Divya B.; Hamblin, Michael R.

2010-01-01

Throughout most of history, serious burns occupying a large percentage of body surface area were an almost certain death sentence because of subsequent infection. A number of factors such as disruption of the skin barrier, ready availability of bacterial nutrients in the burn milieu, destruction of the vascular supply to the burned skin, and systemic disturbances lead to immunosuppression combined together to make burns particularly susceptible to infection. In the 20th century the introduction of antibiotic and antifungal drugs, the use of topical antimicrobials that could be applied to burns, and widespread adoption of early excision and grafting all helped to dramatically increase survival. However the relentless increase in microbial resistance to antibiotics and other antimicrobials has led to a renewed search for alternative approaches to prevent and combat burn infections. This review will cover patented strategies that have been issued or filed with regard to new topical agents, preparations, and methods of combating burn infections. Animal models that are used in preclinical studies are discussed. Various silver preparations (nanocrystalline and slow release) are the mainstay of many approaches but antimicrobial peptides, topical photodynamic therapy, chitosan preparations, new iodine delivery formulations, phage therapy and natural products such as honey and essential oils have all been tested. This active area of research will continue to provide new topical antimicrobials for burns that will battle against growing multi-drug resistance. PMID:20429870

11. [Classical topical therapy of psoriasis].

PubMed

Gerdes, S; Mrowietz, U

2006-08-01

In most cases mild to moderate forms of psoriasis can be treated with topical therapy. In addition, topical agents are also routinely combined with UV or systemic therapy to treat severe forms of psoriasis. A variety of standard products are available. The oldest topical treatment is anthralin. Since 1952 the development of topical corticosteroids has revolutionized not only dermatological treatment in general but the treatment of psoriasis in particular. Through the continuous development of these compounds, a better risk-benefit profile has been achieved. Corticosteroids are the most frequently employed topical agent for psoriasis treatment worldwide. PMID:16841204

12. Armored Geomembrane Cover Engineering

PubMed Central

Foye, Kevin

2011-01-01

Geomembranes are an important component of modern engineered barriers to prevent the infiltration of stormwater and runoff into contaminated soil and rock as well as waste containment facilities—a function generally described as a geomembrane cover. This paper presents a case history involving a novel implementation of a geomembrane cover system. Due to this novelty, the design engineers needed to assemble from disparate sources the design criteria for the engineering of the cover. This paper discusses the design methodologies assembled by the engineering team. This information will aid engineers designing similar cover systems as well as environmental and public health professionals selecting site improvements that involve infiltration barriers. PMID:21776229

13. Current Topics In STEM Education Policy

Glembo, Tyler

2015-04-01

The role of the federal government in education is a hotly debated topic in Congress, causing education to become deeply embedded in politics. Federal funding of education, although covering only about ten percent of total cost, has large impact in the classroom, from testing standards to low interest student loans. This talk will examine the current landscape in physics education including issues facing the community at a national/federal level and also legislation such as the Elementary and Secondary Education Act. We will also examine how stakeholders can develop effective messages and participate in discussions with policy makers.

14. Preface to Special Topic: Marine Renewable Energy

SciTech Connect

Pinto, F. T.; Iglesias, G.; Santos, P. R.; Deng, Zhiqun

2015-12-30

Marine renewable energy (MRE) is generates from waves, currents, tides, and thermal resources in the ocean. MRE has been identified as a potential commercial-scale source of renewable energy. This special topic presents a compilation of works selected from the 3rd IAHR Europe Congress, held in Porto, Portugal, in 2014. It covers different subjects relevant to MRE, including resource assessment, marine energy sector policies, energy source comparisons based on levelized cost, proof-of-concept and new-technology development for wave and tidal energy exploitation, and assessment of possible inference between wave energy converters (WEC).

15. Topics in statistical mechanics

SciTech Connect

Elser, V.

1984-05-01

This thesis deals with four independent topics in statistical mechanics: (1) the dimer problem is solved exactly for a hexagonal lattice with general boundary using a known generating function from the theory of partitions. It is shown that the leading term in the entropy depends on the shape of the boundary; (2) continuum models of percolation and self-avoiding walks are introduced with the property that their series expansions are sums over linear graphs with intrinsic combinatorial weights and explicit dimension dependence; (3) a constrained SOS model is used to describe the edge of a simple cubic crystal. Low and high temperature results are derived as well as the detailed behavior near the crystal facet; (4) the microscopic model of the lambda-transition involving atomic permutation cycles is reexamined. In particular, a new derivation of the two-component field theory model of the critical behavior is presented. Results for a lattice model originally proposed by Kikuchi are extended with a high temperature series expansion and Monte Carlo simulation. 30 references.

16. Discovering Health Topics in Social Media Using Topic Models

PubMed Central

Paul, Michael J.; Dredze, Mark

2014-01-01

By aggregating self-reported health statuses across millions of users, we seek to characterize the variety of health information discussed in Twitter. We describe a topic modeling framework for discovering health topics in Twitter, a social media website. This is an exploratory approach with the goal of understanding what health topics are commonly discussed in social media. This paper describes in detail a statistical topic model created for this purpose, the Ailment Topic Aspect Model (ATAM), as well as our system for filtering general Twitter data based on health keywords and supervised classification. We show how ATAM and other topic models can automatically infer health topics in 144 million Twitter messages from 2011 to 2013. ATAM discovered 13 coherent clusters of Twitter messages, some of which correlate with seasonal influenza (r = 0.689) and allergies (r = 0.810) temporal surveillance data, as well as exercise (r = .534) and obesity (r = −.631) related geographic survey data in the United States. These results demonstrate that it is possible to automatically discover topics that attain statistically significant correlations with ground truth data, despite using minimal human supervision and no historical data to train the model, in contrast to prior work. Additionally, these results demonstrate that a single general-purpose model can identify many different health topics in social media. PMID:25084530

17. ENGINEERING BULLETIN: LANDFILL COVERS

EPA Science Inventory

Landfill covers are used at Superfund sites to minimize surface water infiltration and control gas migration. In many cases covers are used in conjunction with other waste treatment technologies, such as slurry walls, ground water pump-and-treat systems, and gas collection. This ...

18. Silostop Bunker Covers

Technology Transfer Automated Retrieval System (TEKTRAN)

The quality of the seal provided by the plastic cover is a key issue for minimizing losses in bunker and pile silos. Most bunker covers are 6 to 8 mil polyethylene sheets held in place by tires or tire sidewalls. Frequently there are problems with spoilage at the shoulders (i.e., against the walls),...

19. On the Cover

ERIC Educational Resources Information Center

Hays, Kate F.

2006-01-01

This is a discussion with Judith Warren regarding her painting on the cover of the present issue of American Psychologist. To Warren, the painting on the cover of this issue, Pentimento, speaks to the interplay of spontaneity and intentionality in psychotherapy.

20. Land Cover Trends Project

USGS Publications Warehouse

Acevedo, William

2006-01-01

The Land Cover Trends Project is designed to document the types, rates, causes, and consequences of land cover change from 1973 to 2000 within each of the 84 U.S. Environmental Protection Agency (EPA) Level III ecoregions that span the conterminous United States. The project's objectives are to: * Develop a comprehensive methodology using probability sampling and change analysis techniques and Landsat Multispectral Scanner (MSS), Thematic Mapper (TM), and Enhanced Thematic Mapper (ETM) data for estimating regional land cover change. * Characterize the spatial and temporal characteristics of conterminous U.S. land cover change for five periods from 1973 to 2000 (nominally 1973, 1980, 1986, 1992, and 2000). * Document the regional driving forces and consequences of change. * Prepare a national synthesis of land cover change.

1. Topicality 1 and Topicality 2: A Quest for True Meaning.

ERIC Educational Resources Information Center

Olson, Clark D.; Vasilius, Janet M.

The actual nature of topicality as it is presented in intercollegiate debate rounds has become so split that there are two different types of topicality. The first type (T1) is a "real" argument that is subjective, intentional, absolute, jurisdictional, pragmatic, and focuses on content and product. The second type (T2) is strategic, objective,…

2. Topical Knowledge and Topical Interest Predictors of Listening Comprehension.

ERIC Educational Resources Information Center

Hare, Victoria Chou; Devine, Denise A.

A study was designed to determine whether scores for general knowledge, specific knowledge, and general interest on a topic could be used as predictors of children's listening comprehension. Baseball and dolls were chosen as the topics because their stereotypic nature would allow the data to be generalized across the subject population. Data were…

3. Land Cover Characterization Program

USGS Publications Warehouse

U.S. Geological Survey

1997-01-01

(2) identify sources, develop procedures, and organize partners to deliver data and information to meet user requirements. The LCCP builds on the heritage and success of previous USGS land use and land cover programs and projects. It will be compatible with current concepts of government operations, the changing needs of the land use and land cover data users, and the technological tools with which the data are applied.

4. WATER COOLED RETORT COVER

DOEpatents

Ash, W.J.; Pozzi, J.F.

1962-05-01

A retort cover is designed for use in the production of magnesium metal by the condensation of vaporized metal on a collecting surface. The cover includes a condensing surface, insulating means adjacent to the condensing surface, ind a water-cooled means for the insulating means. The irrangement of insulation and the cooling means permits the magnesium to be condensed at a high temperature and in massive nonpyrophoric form. (AEC)

5. Linguistic Extensions of Topic Models

ERIC Educational Resources Information Center

Boyd-Graber, Jordan

2010-01-01

Topic models like latent Dirichlet allocation (LDA) provide a framework for analyzing large datasets where observations are collected into groups. Although topic modeling has been fruitfully applied to problems social science, biology, and computer vision, it has been most widely used to model datasets where documents are modeled as exchangeable…

6. Hot topics for leadership development.

PubMed

Bleich, Michael R

2015-02-01

Three areas stand out from a health systems perspective that should be on the development agenda for all leaders. These topics include population health, predictive analytics, and supply chain management. Together, these topics address access, quality, and cost management. PMID:25633301

7. CounselorQuest: Concise Analyses of Critical Counseling Topics.

ERIC Educational Resources Information Center

Walz, Garry R., Comp.

This document contains 167 Educational Resources and Information Center (ERIC) digests from eight ERIC Clearinghouses covering topics of interest to counselors who work with clients from preschool age through adults. Digests are organized alphabetically by title; three indices help users locate digests alphabetically, by educational level, and by…

8. Single photon emission computed tomography and other selected computer topics

SciTech Connect

Price, R.R.; Gilday, D.L.; Croft, B.Y.

1980-01-01

This volume includes an overview of single photon emission computed tomography and numerous papers that describe and evaluate specific systems and techniques. Papers cover such topics as Auger cameras; seven-pinhole and slant-hole collimators; brain; cardiac; and gated blood-pool studies; and the BICLET and SPECT systems.

9. Accelerators, Beams And Physical Review Special Topics - Accelerators And Beams

SciTech Connect

Siemann, R.H.; /SLAC

2011-10-24

Accelerator science and technology have evolved as accelerators became larger and important to a broad range of science. Physical Review Special Topics - Accelerators and Beams was established to serve the accelerator community as a timely, widely circulated, international journal covering the full breadth of accelerators and beams. The history of the journal and the innovations associated with it are reviewed.

10. Advancements in Topical Antifungal Vehicles.

PubMed

Kircik, Leon H

2016-02-01

The primary treatment for superficial fungal infections is antifungal topical formulations, and allylamines and azoles represent the two major classes of topical formulations that are used to treat these infections. The stratum corneum (SC) is composed of keratinocytes that are surrounded by a matrix of lipids. The efficacy of topically applied formulations depends on their ability to penetrate this lipid matrix, and the vehicle plays an integral role in the penetration of active molecule into skin. There are several challenges to formulating topical drugs, which include the biotransformation of the active molecules as they pass through the SC and the physical changes that occur to the vehicle itself when it is applied to the skin. This article will review current and emerging topical antifungal vehicles. PMID:26885798

11. Topic Model for Graph Mining.

PubMed

Xuan, Junyu; Lu, Jie; Zhang, Guangquan; Luo, Xiangfeng

2015-12-01

Graph mining has been a popular research area because of its numerous application scenarios. Many unstructured and structured data can be represented as graphs, such as, documents, chemical molecular structures, and images. However, an issue in relation to current research on graphs is that they cannot adequately discover the topics hidden in graph-structured data which can be beneficial for both the unsupervised learning and supervised learning of the graphs. Although topic models have proved to be very successful in discovering latent topics, the standard topic models cannot be directly applied to graph-structured data due to the "bag-of-word" assumption. In this paper, an innovative graph topic model (GTM) is proposed to address this issue, which uses Bernoulli distributions to model the edges between nodes in a graph. It can, therefore, make the edges in a graph contribute to latent topic discovery and further improve the accuracy of the supervised and unsupervised learning of graphs. The experimental results on two different types of graph datasets show that the proposed GTM outperforms the latent Dirichlet allocation on classification by using the unveiled topics of these two models to represent graphs. PMID:25616091

12. Mental Mechanisms for Topics Identification

PubMed Central

2014-01-01

Topics identification (TI) is the process that consists in determining the main themes present in natural language documents. The current TI modeling paradigm aims at acquiring semantic information from statistic properties of large text datasets. We investigate the mental mechanisms responsible for the identification of topics in a single document given existing knowledge. Our main hypothesis is that topics are the result of accumulated neural activation of loosely organized information stored in long-term memory (LTM). We experimentally tested our hypothesis with a computational model that simulates LTM activation. The model assumes activation decay as an unavoidable phenomenon originating from the bioelectric nature of neural systems. Since decay should negatively affect the quality of topics, the model predicts the presence of short-term memory (STM) to keep the focus of attention on a few words, with the expected outcome of restoring quality to a baseline level. Our experiments measured topics quality of over 300 documents with various decay rates and STM capacity. Our results showed that accumulated activation of loosely organized information was an effective mental computational commodity to identify topics. It was furthermore confirmed that rapid decay is detrimental to topics quality but that limited capacity STM restores quality to a baseline level, even exceeding it slightly. PMID:24744775

13. How a Standardized Achievement Test Adapts to the Times: A Topical Comparison of Mathematics and Reading Tests on the 1973 and 1981 Forms of the Comprehensive Tests of Basic Skills.

ERIC Educational Resources Information Center

Mattson, Ann; And Others

This document contains a detailed listing of topics covered in the mathematics and reading portions of the 1973 Form S and the 1981 Form U of the Comprehensive Tests of Basic Skills (CTBS). Chages in the overall structure of the CTBS, new topics included in Form U and old topics not covered, and changes in the arrangement of topics across the…

14. The future of topical analgesics.

PubMed

Arnstein, Paul M

2013-07-01

Topically applied analgesic therapies have been used throughout history to treat a variety of patient conditions that present with pain. Before modem pharmaceuticals became readily available, mud-based emollients, salves, cold therapies, and other natural remedies were often used. Now we have effective therapies and are developing advanced topical analgesics as we learn more about the physiology and pathophysiology of pain. The use of topical analgesics may be associated with fewer patient systemic side effects than are seen with oral, parenteral, or transdermally administered agents, making the topical route of administration attractive to prescribers and patients. With further refinement of existing drugs and the development of novel agents, topical analgesics may offer relief for treating patient pain conditions that are currently challenging to treat, such as pain resulting from burns, wound debridement, and pressure ulcers. Recognizing the value of a multimodal approach, topical analgesics may offer a therapeutic option that can become part of a comprehensive treatment plan for the patient. With continued advancements in targeted drug-delivery systems, topical analgesics may be able to provide a method to prevent or reverse the phenomena of peripheral and central sensitization, or the neuroplastic changes believed to be responsible for the transition from acute to chronic pain states in patients. For those patients at risk for developing chronic pain states, such as complex regional pain syndrome, the combination of cutaneous stimulation (achieved through rubbing during application) and analgesic effects produced by the drug itself may prevent the disabling pain that often emerges during the subacute phase of disease. In summary, better utilization of currently available topical analgesics and continued research promise to ensure that topical analgesics are, and will continue to be, important tools in the treatment of patients with resistant pain. PMID

15. Topical Steroid-Damaged Skin

PubMed Central

Abraham, Anil; Roga, Gillian

2014-01-01

Topical steroids, commonly used for a wide range of skin disorders, are associated with side effects both systemic and cutaneous. This article aims at bringing awareness among practitioners, about the cutaneous side effects of easily available, over the counter, topical steroids. This makes it important for us as dermatologists to weigh the usefulness of topical steroids versus their side effects, and to make an informed decision regarding their use in each individual based on other factors such as age, site involved and type of skin disorder. PMID:25284849

16. Automatic cloud cover mapping.

NASA Technical Reports Server (NTRS)

Strong, J. P., III; Rosenfeld, A.

1971-01-01

A method of converting a picture into a 'cartoon' or 'map' whose regions correspond to differently textured regions is described. Texture edges in the picture are detected, and solid regions surrounded by these (usually broken) edges are 'colored in' using a propagation process. The resulting map is cleaned by comparing the region colors with the textures of the corresponding regions in the picture, and also by merging some regions with others according to criteria based on topology and size. The method has been applied to the construction of cloud cover maps from cloud cover pictures obtained by satellites.

17. Reusable pipe flange covers

DOEpatents

Holden, James Elliott; Perez, Julieta

2001-01-01

A molded, flexible pipe flange cover for temporarily covering a pipe flange and a pipe opening includes a substantially round center portion having a peripheral skirt portion depending from the center portion, the center portion adapted to engage a front side of the pipe flange and to seal the pipe opening. The peripheral skirt portion is formed to include a plurality of circumferentially spaced tabs, wherein free ends of the flexible tabs are formed with respective through passages adapted to receive a drawstring for pulling the tabs together on a back side of the pipe flange.

18. Health Topics: MedlinePlus

MedlinePlus

... https://www.nlm.nih.gov/medlineplus/healthtopics.html Health Topics To use the sharing features on this ... Children and Teenagers Men Population Groups Seniors Women Health and Wellness Disasters Fitness and Exercise Food and ...

19. Higher Education in the News: A Look into the Topics, Sources, and Views of the Print Media.

ERIC Educational Resources Information Center

Devitt, James

This study examined how higher education is represented in the press by analyzing how four leading newspapers, "The New York Times,""USA Today,""The Washington Post," and "The Wall Street Journal," covered higher education in 1997. The study analyzed a total of 610 higher education stories covering 21 topics. The 10 topics on which articles were…

20. Topical treatment of hyperpigmentation disorders.

PubMed

Rendon, M; Horwitz, S

2012-12-01

Hyperpigmentation has traditionally been a relatively difficult condition to treat, especially in darker racial ethnic groups. Multiple topical agents available act upon different steps of the pigmentation pathway. We review these topical agents, their mechanisms of action, and their effectiveness as monotherapy and in combination with other compounds. Ultimately, combination therapy is the most efficacious when considering overall depigmentation as well as treatment time required to achieve clinical improvement. PMID:23522631

1. Issue Cover (June 2016).

PubMed

2016-06-01

Cover legend: Yeast cells were labeled with the fluorescent viability dyes propidium iodide (Red) and DiBAC4(3) (green) and the nucleus was stained with DAPI (blue). Cells were visualized using wide-field fluorescent microscopy. See Chadwick et al. Traffic 2016; 17(6):689-703. Read the full article on doi:10.1111/tra.12391. PMID:27174376

2. Instrument measures cloud cover

NASA Technical Reports Server (NTRS)

Laue, E. G.

1981-01-01

Eight solar sensing cells comprise inexpensive monitoring instrument. Four cells always track Sun while other four face sky and clouds. On overcast day, cloud-irradiance sensors generate as much short-circuit current as Sun sensor cells. As clouds disappear, output of cloud sensors decreases. Ratio of two sensor type outputs determines fractional cloud cover.

3. Success with cover crops

Technology Transfer Automated Retrieval System (TEKTRAN)

Cover crops are an important tool for producers interested in improving soil and crop productivity. They help control erosion, improve soil quality, improve soil properties that impact water infiltration and conservation, provide habitat and food for beneficial insects, and provide food for wildlif...

4. Issue Cover (September 2016).

PubMed

2016-09-01

Cover legend: Macrophages phagocytosing RFP-labeled E.coli. GFP-APPL2 labels the phagosomal membrane. Image produced by N. Condon. See Yeo et al. Traffic 2016; 17(9):1014-1026. Read the full article on doi:10.1111/tra.12415. PMID:27510703

5. Covering All Options

ERIC Educational Resources Information Center

Kennedy, Mike

2011-01-01

The day a school opens its doors for the first time, the flooring will be new and untarnished. When the flooring is in such pristine condition, many flooring materials--carpeting, vinyl, terrazzo, wood or some other surface--will look good. But school and university planners who decide what kind of material covers the floors of their facilities…

6. I.P.P.E.S. Master Objectives Bank, Mathematics Instructional Topic Catalog.

ERIC Educational Resources Information Center

Jackson Union School District, MI.

The coding system used to classify items in the Instructional Program Planning and Evaluation System (IPPES) Master Objectives Bank is explained. Sixty-seven topics in mathematics to be covered in grades kindergarten through six are specified; objectives are listed under these topics along with their code numbers. (For a listing by grade level,…

7. "The Strawberry Caper": Using Scenario-Based Problem Solving to Integrate Middle School Science Topics

ERIC Educational Resources Information Center

Gonda, Rebecca L.; DeHart, Kyle; Ashman, Tia-Lynn; Legg, Alison Slinskey

2015-01-01

Achieving a deep understanding of the many topics covered in middle school biology classes is difficult for many students. One way to help students learn these topics is through scenario-based learning, which enhances students' performance. The scenario-based problem-solving module presented here, "The Strawberry Caper," not only…

8. Issue Cover (July 2016).

PubMed

2016-07-01

Cover legend: N-cadherin clusters colocalize with Rab5 at the macropinosomes. Confocal microscopy image of an Ncad-GFP (green) transfected COS7 cell fed with fluorescent-dextran to label macropinosomes (blue) followed by immunofluorescence staining of Rab5 (red) and the nucleus (cyan). See Wen et al. Traffic 2016; 17(7):769-785. Read the full article on doi: 10.1111/tra.12402. PMID:27297702

9. Peregrinations through topics in light scattering and radiative transfer

Kattawar, George W.

2016-07-01

In this van de Hulst essay, I have taken the liberty to present a journey through some topics in light scattering and radiative transfer which I feel were major contributions to the field but the number of topics I would like to cover is far more numerous than I have the time or the space to present. I also wanted to share with the reader some heartwarming memories I have of my wonderful friend and truly distinguished colleague Hendrik Christoffel van de Hulst (affectionately known to his colleagues as "Henk") whom I consider to be one of the preeminent scientists of his era.

10. Topical antimicrobials for burn infections - an update.

PubMed

Sevgi, Mert; Toklu, Ani; Vecchio, Daniela; Hamblin, Michael R

2013-12-01

The relentless rise in antibiotic resistance among pathogenic bacteria and fungi, coupled with the high susceptibility of burn wounds to infection, and the difficulty of systemically administered antibiotics to reach damaged tissue, taken together have made the development of novel topical antimicrobials for burn infections a fertile area of innovation for researchers and companies. We previously covered the existing patent literature in this area in 2010, but the notable progress made since then, has highlighted the need for an update to bring the reader up to date on recent developments. New patents in the areas of topically applied antibiotics and agents that can potentiate the action of existing antibiotics may extend their useful lifetime. Developments have also been made in biofilm-disrupting agents. Antimicrobial peptides are nature's way for many life forms to defend themselves against attack by pathogens. Silver has long been known to be a highly active antimicrobial but new inorganic metal derivatives based on bismuth, copper and gallium have emerged. Halogens such as chlorine and iodine can be delivered by novel technologies. A variety of topically applied antimicrobials include chitosan preparations, usnic acid, ceragenins and XF porphyrins. Natural product derived antimicrobials such as tannins and essential oils have also been studied. Novel techniques to deliver reactive oxygen species and nitric oxide in situ have been developed. Light-mediated techniques include photodynamic therapy, ultraviolet irradiation, blue light, low-level laser therapy and titania photocatalysis. Passive immunotherapy employs antibodies against pathogens and their virulence factors. Finally an interesting new area uses therapeutic microorganisms such as phages, probiotic bacteria and protozoa to combat infections. PMID:24215506

11. Topics

ERIC Educational Resources Information Center

Mathematics Teaching, 1972

1972-01-01

This column discusses problems involving a paper folding game for bicimals, the sum of exterior angles of polygons and polyhedra, solving quadratic equations in finite arithmetics, nomograms, and cube folding patterns. (DT)

12. Topics

ERIC Educational Resources Information Center

Mathematics Teaching, 1971

1971-01-01

Problems involving divisibility, the ten coin triangle, five times a week with 4 D, a nomogram for the lens formula, the box and ladder problem, chains of circles, tessellating hexagons, topological woggles, and numbers of triangles are discussed. (CT)

13. Topics

ERIC Educational Resources Information Center

Mathematics Teaching, 1971

1971-01-01

Notes on divisibility using manipulative materials, cyclic groups of functions, Horner's method of synthetic division, arc lengths of cycloids and cardioids, number squares, and students' concepts of mathematics. (MM)

14. Topics

ERIC Educational Resources Information Center

Mathematics Teaching, 1971

1971-01-01

Notes on De Morgan's rules; a perpetual calendar; the use of coloured rods; a balance problem; a graphical approach to natural logarithms; a problem in geometric probability; and the parallelogram law of forces. (MM)

15. Topical corticosteroid addiction and phobia.

PubMed

Ghosh, Aparajita; Sengupta, Sujata; Coondoo, Arijit; Jana, Amlan Kusum

2014-09-01

Corticosteroids, one of the most widely prescribed topical drugs, have been used for about six decades till date. However, rampant misuse and abuse down the years has given the drug a bad name. Topical steroid abuse may lead to two major problems which lie at the opposing ends of the psychosomatic spectrum. Topical steroid addiction, a phenomenon that came to be recognized about a decade after the introduction of the molecule is manifested as psychological distress and rebound phenomenon on stoppage of the drug. The rebound phenomenon, which can affect various parts of the body particularly the face and the genitalia has been reported by various names in the literature. TC phobia which lies at the opposite end of the psychiatric spectrum of steroid abuse has been reported particularly among parents of atopic children. Management of both conditions is difficult and frustrating. Psychological counseling and support can be of immense help in both the conditions. PMID:25284851

16. Topical Corticosteroid Addiction and Phobia

PubMed Central

Ghosh, Aparajita; Sengupta, Sujata; Coondoo, Arijit; Jana, Amlan Kusum

2014-01-01

Corticosteroids, one of the most widely prescribed topical drugs, have been used for about six decades till date. However, rampant misuse and abuse down the years has given the drug a bad name. Topical steroid abuse may lead to two major problems which lie at the opposing ends of the psychosomatic spectrum. Topical steroid addiction, a phenomenon that came to be recognized about a decade after the introduction of the molecule is manifested as psychological distress and rebound phenomenon on stoppage of the drug. The rebound phenomenon, which can affect various parts of the body particularly the face and the genitalia has been reported by various names in the literature. TC phobia which lies at the opposite end of the psychiatric spectrum of steroid abuse has been reported particularly among parents of atopic children. Management of both conditions is difficult and frustrating. Psychological counseling and support can be of immense help in both the conditions. PMID:25284851

17. Haloprogin: a Topical Antifungal Agent

PubMed Central

Harrison, E. F.; Zwadyk, P.; Bequette, R. J.; Hamlow, E. E.; Tavormina, P. A.; Zygmunt, W. A.

1970-01-01

Haloprogin was shown to be a highly effective agent for the treatment of experimentally induced topical mycotic infections in guinea pigs. Its in vitro spectrum of activity also includes yeasts, yeastlike fungi (Candida species), and certain gram-positive bacteria. The in vitro and in vivo antifungal activity of haloprogin against dermatophytes was equal to that observed with tolnaftate. The striking differences between the two agents were the marked antimonilial and selective antibacterial activities shown by haloprogin, contrasted with the negligible activities found with tolnaftate. Addition of serum decreased the in vitro antifungal activity of haloprogin to a greater extent than that of tolnaftate; however, diminished antifungal activity was not observed when haloprogin was applied topically to experimental dermatophytic infections. Based on its broad spectrum of antimicrobial activity, haloprogin may prove to be a superior topical agent in the treatment of dermatophytic and monilial infections in man. PMID:5422306

18. Topical treatments for hypertrophic scars.

PubMed

Zurada, Joanna M; Kriegel, David; Davis, Ira C

2006-12-01

Hypertrophic scars represent an abnormal, exaggerated healing response after skin injury. In addition to cosmetic concern, scars may cause pain, pruritus, contractures, and other functional impairments. Therapeutic modalities include topical medications, intralesional corticosteroids, laser therapy, and cryosurgery. Topical therapies, in particular, have become increasingly popular because of their ease of use, comfort, noninvasiveness, and relatively low cost. This review will discuss the properties and effectiveness of these agents, including pressure therapy, silicone gel sheeting and ointment, polyurethane dressing, onion extract, imiquimod 5% cream, and vitamins A and E in the prevention and treatment of hypertrophic scars. PMID:17097399

19. Issue Cover (May 2016).

PubMed

2016-05-01

Cover legend: Distribution of organelles that bound TYRP1-FKBP-mCherry (red) and mitochondria revealed with MitoTracker Deep Red dye (green) in the cytoplasm of a Xenopus melanophore. Rezaul et al. show TYRP1-FKBP-mCherry specifically binds to pigment granules and in the presence of rapalog recruits exogenous microtubule motor protein kinesin-1-EGFP-FRB, which changes net direction of granule movement. See Rezaul et al Traffic 2016; 17(5):475-486. Read the full article on doi:10.1111/tra.12385. PMID:27093334

20. Issue Cover (August 2016).

PubMed

2016-08-01

Cover legend: Absence of the novel endolysosomal trafficking regulator WDR81 (green) induces the accumulation of tetherin (red) in enlarged early endosomes. WDR81 knock-out HeLa cells were genetically complemented with an HA-tagged WDR81 construct and imaged by confocal immunofluorescence microscopy. The original image was processed with photo editing software and overlaid with artistic effects. See Rapiteanu et al. Traffic 2016; 17(8):940-958. Read the full article on doi: 10.1111/tra.12409. PMID:27412792

1. Vital Topics in School Finance.

ERIC Educational Resources Information Center

Garber, Darrell H.

A study to determine the topics considered vital by principals and members of the American Education Finance Association (AEFA) is described in this paper. Questionnaires mailed to two random samples of 61 AEFA members and 181 elementary/secondary principals respectively, yielded 35 returns, a 57 percent response rate, and 113 returns, a 62…

2. Resources for Topics in Nursing.

ERIC Educational Resources Information Center

Riordan, Dale B.

This guide is intended to help the user become familiar with a selected group of reference tools and resources which are useful in nursing education and practice. It is important for students to use the correct medical or scientific terminology, understand the scope of a topic, and then utilize the tools necessary to research subjects of interest.…

3. Topics in optics and music

Sparks, Andrew W.

2012-10-01

While the use of optics in the playback of music has been a tremendously successful technology and laser light shows are a common occurrence, other intersections of optics and music tend to be less well known. Topics such as optics-based instruments, performance tools and effects, instrument characterization and manufacturing, recording, playback, and signal processing are explored.

4. Topical Knowledge and ESL Writing

ERIC Educational Resources Information Center

He, Ling; Shi, Ling

2012-01-01

This study investigates the effects of topical knowledge on ESL (English as a Second Language) writing performance in the English Language Proficiency Index (LPI), a standardized English proficiency test used by many post-secondary institutions in western Canada. The participants were 50 students with different levels of English proficiency…

5. Topic Development in USENET Newsgroups.

ERIC Educational Resources Information Center

Osborne, Larry N.

1998-01-01

USENET newsgroup topics are created, and they evolve, mutate, and become extinct in ways fundamentally different from spoken dialog. These differences can be explained partially by the asynchronous nature of electronic communication, as well as by other factors unique to such wide-scale multi-user media. (Author)

6. The Health Curriculum: 500 Topics.

ERIC Educational Resources Information Center

Byrd, Oliver E.

2001-01-01

This 1958 paper divides 500 health topics into 20 categories: health as a social accomplishment/social problem; nutrition; physical fitness; mental health and disease; heredity/eugenics; infection/immunity; chronic and degenerative disease; substance abuse; skin care; vision, hearing, and speech; dental health; safety; physical environment; health…

7. Seven topics in perturbative QCD

SciTech Connect

Buras, A.J.

1980-09-01

The following topics of perturbative QCD are discussed: (1) deep inelastic scattering; (2) higher order corrections to e/sup +/e/sup -/ annihilation, to photon structure functions and to quarkonia decays; (3) higher order corrections to fragmentation functions and to various semi-inclusive processes; (4) higher twist contributions; (5) exclusive processes; (6) transverse momentum effects; (7) jet and photon physics.

8. Helping Kids Choose a Topic.

ERIC Educational Resources Information Center

Bunce-Crim, Marna

1991-01-01

Thinking about how published authors get their ideas for stories is one way for children to generate their own story ideas. The article discusses how elementary teachers can use storytelling, reading, examining picture books, and learning writing techniques to help their students select a topic. (SM)

9. Conducting Surveys on Sensitive Topics

ERIC Educational Resources Information Center

Pryor, John H.

2004-01-01

Many institutions are surveying students about sensitive topics such as alcohol and drug use, sexual behavior, and academic dishonesty. Yet these can be some of the most difficult surveys to administer successfully, given reluctance on the part of respondents both to participate and to provide truthful answers. (Contains 1 table.)

10. Vocational Education Today: Topical Issues.

ERIC Educational Resources Information Center

Kenway, Jane, Ed.; Tregenza, Karen, Ed.; Watkins, Peter, Ed.

This book contains 13 papers examining topical issues in vocational education and training (VET) in Victoria, Australia. The following papers are included: "Vocational Education and Schooling: The Changing Scene" (Jane Kenway, Sue Willis, Peter Watkins, Karen Tregenza); "The Enterprise Approach" (James Mulraney); "VET Programs at James Harrison…

11. Topics in Biomedical Optics: Introduction

Hebden, Jeremy C.; Boas, David A.; George, John S.; Durkin, Anthony J.

2003-06-01

The field of biomedical optics is experiencing tremendous growth. Biomedical technologies contribute in the creation of devices used in healthcare of various specialties (ophthalmology, cardiology, anesthesiology, and immunology, etc.). Recent research in biomedical optics is discussed. Overviews of meetings held at the 2002 Optical Society of America Biomedical Topical Meetings are presented.

12. Topics in Bioethics: A Development of Student Perspectives†

PubMed Central

Johnson, Keith A.

2014-01-01

Exposing students to current biotechnological and medical issues is eye-opening for many students in a way that is not always achieved through lecture-based learning. Lecture or investigative teaching styles provide a tremendous knowledge base for the students, but sometimes these teaching styles do not allow the student to fully develop, especially personal attitudes to issues in bioethics. Through online videos, Hollywood movies, guided readings and classroom discussions, students in this course are informed of some bioethical topics, encouraged to learn about other topics, and use this gained knowledge to develop personal positions regarding the value and/or risk of the issues. This course has been well-received by previous students as a favorite in terms of both topics covered and style. PMID:25574290

13. THE TOPIC OF RESEARCH INTEGRITY IN LATINAMERICA1

PubMed Central

Rodríguez, Eduardo; Lolas, Fernando

2012-01-01

Present article narrates the experience of trainees of the ethics of biomedical and psychosocial research program of the Interdisciplinary Center for studies on bioethics (CIEB) of the University of Chile on the topic of research integrity in Latin America. The following problems are covered: integrity of publications, reporting of scientific research misconduct, definitions of research integrity, scientific ethical review committees functioning, international multi-centric clinical trials monitoring and norms for scientific integrity and ethical oversight. PMID:22679532

14. Do scientists trace hot topics?

PubMed Central

Wei, Tian; Li, Menghui; Wu, Chensheng; Yan, Xiao-Yong; Fan, Ying; Di, Zengru; Wu, Jinshan

2013-01-01

Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of papers belonging to the field. This indicates that scientists generally do follow hot topics. However, there are qualitative differences among scientists from various countries, among research works regarding different number of authors, different number of affiliations and different number of references. These observations could be valuable for policy makers when deciding research funding and also for individual researchers when searching for scientific projects. PMID:23856680

15. Retapamulin: a newer topical antibiotic.

PubMed

Dhingra, D; Parakh, A; Ramachandran, S

2013-01-01

Impetigo is a common childhood skin infection. There are reports of increasing drug resistance to the currently used topical antibiotics including fusidic acid and mupirocin. Retapamulin is a newer topical agent of pleuromutilin class approved by the Food and Drug Administration for treatment of impetigo in children and has been recently made available in the Indian market. It has been demonstrated to have low potential for the development of antibacterial resistance and a high degree of potency against poly drug resistant Gram-positive bacteria found in skin infections including Staphylococcus aureus strains. The drug is safe owing to low systemic absorption and has only minimal side-effect of local irritation at the site of application. PMID:23793314

16. Major research topics in combustion

SciTech Connect

Hussaini, M.Y.; Kumar, A.; Voigt, R.G.

1992-01-01

The Institute for Computer Applications in Science and Engineering (ICASE) and NASA Langley Research Center (LaRC) hosted a workshop on October 2--4, 1989 to discuss some combustion problems of technological interest to LaRC and to foster interaction with the academic community in these research areas. The topics chosen for this purpose were flame structure, flame holding/extinction, chemical kinetics, turbulence-kinetics interaction, transition to detonation, and reacting free shear layers. This document contains the papers and edited versions of general discussions on these topics. The lead paper set the stage for the meeting by discussing the status and issues of supersonic combustion relevant to the scramjet engine. Experts were then called upon to review the current knowledge in the aforementioned areas, to focus on how this knowledge can be extended and applied to high-speed combustion, and to suggest future directions of research in these areas.

17. Topical fluoride for caries prevention

PubMed Central

Weyant, Robert J.; Tracy, Sharon L.; Anselmo, Theresa (Tracy); Beltrán-Aguilar, Eugenio D.; Donly, Kevin J.; Frese, William A.; Hujoel, Philippe P.; Iafolla, Timothy; Kohn, William; Kumar, Jayanth; Levy, Steven M.; Tinanoff, Norman; Wright, J. Timothy; Zero, Domenick; Aravamudhan, Krishna; Frantsve-Hawley, Julie; Meyer, Daniel M.

2015-01-01

Background A panel of experts convened by the American Dental Association (ADA) Council on Scientific Affairs presents evidence-based clinical recommendations regarding professionally applied and prescription-strength, home-use topical fluoride agents for caries prevention. These recommendations are an update of the 2006 ADA recommendations regarding professionally applied topical fluoride and were developed by using a new process that includes conducting a systematic review of primary studies. Types of Studies Reviewed The authors conducted a search of MEDLINE and the Cochrane Library for clinical trials of professionally applied and prescription-strength topical fluoride agents—including mouthrinses, varnishes, gels, foams and pastes—with caries increment outcomes published in English through October 2012. Results The panel included 71 trials from 82 articles in its review and assessed the efficacy of various topical fluoride caries-preventive agents. The panel makes recommendations for further research. Practical Implications The panel recommends the following for people at risk of developing dental caries: 2.26 percent fluoride varnish or 1.23 percent fluoride (acidulated phosphate fluoride) gel, or a prescription-strength, home-use 0.5 percent fluoride gel or paste or 0.09 percent fluoride mouthrinse for patients 6 years or older. Only 2.26 percent fluoride varnish is recommended for children younger than 6 years. The strengths of the recommendations for the recommended products varied from “in favor” to “expert opinion for.” As part of the evidence-based approach to care, these clinical recommendations should be integrated with the practitioner's professional judgment and the patient's needs and preferences. PMID:24177407

18. Cushing's syndrome from topical glucocorticoids.

PubMed

Teelucksingh, S; Bahall, M; Coomansingh, D; Suite, M; Bartholomew, C

1993-06-01

A case of Cushing's syndrome is described in a woman who self-treated psoriasis with a variety of potent topical glucocorticoids over 15 years. She was successfully weaned off corticosteroids and was treated with alternative anti-psoriatic drugs. The disappearance, nine months later, of most features of Cushing's syndrome, and the normal suppression of cortisol in response to dexamethasone, excluded endogenous hypercorticolism. The apparent widespread availability across the counter of potent corticosteroids is a cause for concern. PMID:8367969

19. TOPTRAC: Topical Trajectory Pattern Mining

PubMed Central

Kim, Younghoon; Han, Jiawei; Yuan, Cangzhou

2015-01-01

With the increasing use of GPS-enabled mobile phones, geo-tagging, which refers to adding GPS information to media such as micro-blogging messages or photos, has seen a surge in popularity recently. This enables us to not only browse information based on locations, but also discover patterns in the location-based behaviors of users. Many techniques have been developed to find the patterns of people's movements using GPS data, but latent topics in text messages posted with local contexts have not been utilized effectively. In this paper, we present a latent topic-based clustering algorithm to discover patterns in the trajectories of geo-tagged text messages. We propose a novel probabilistic model to capture the semantic regions where people post messages with a coherent topic as well as the patterns of movement between the semantic regions. Based on the model, we develop an efficient inference algorithm to calculate model parameters. By exploiting the estimated model, we next devise a clustering algorithm to find the significant movement patterns that appear frequently in data. Our experiments on real-life data sets show that the proposed algorithm finds diverse and interesting trajectory patterns and identifies the semantic regions in a finer granularity than the traditional geographical clustering methods. PMID:26709365

20. VEGETATIVE COVERS FOR WASTE CONTAINMENT

EPA Science Inventory

Disposal of municipal ahd hazardous waste in the United States is primarily accomplished by containment in lined and capped landfills. Evapotranspiration cover systems offer an alternative to conventional landfill cap systems. These covers work on completely different principles ...

1. Cover crops and N credits

Technology Transfer Automated Retrieval System (TEKTRAN)

Cover crops often provide many short- and long-term benefits to cropping systems. Legume cover crops can significantly reduce the N fertilizer requirement of non-legume cash crops that follow. The objectives of this presentation were to: I) educate stakeholders about the potential benefits of cover ...

2. Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch

PubMed Central

Lionberger, David R; Brennan, Michael J

2010-01-01

The objective of this article is to review published clinical data on diclofenac epolamine topical patch 1.3% (DETP) in the treatment of acute soft tissue injuries, such as strains, sprains, and contusions. Review of published literature on topical nonsteroidal anti-inflammatory drugs (NSAIDs), diclofenac, and DETP in patients with acute soft tissue injuries was included. Relevant literature was identified on MEDLINE using the search terms topical NSAIDs, diclofenac, diclofenac epolamine, acute pain, sports injury, soft tissue injury, strain, sprain, and contusion, and from citations in retrieved articles covering the years 1978–2008. Review of published, randomized clinical trials and meta-analyses shows that topical NSAIDs are significantly more effective than placebo in relieving acute pain; the pooled average relative benefit was 1.7 (95% confidence interval, 1.5–1.9). In a limited number of comparisons, topical and oral NSAIDs provided comparable pain relief, but the use of topical agents produced lower plasma drug concentrations and fewer systemic adverse events (AEs). The physical–chemical properties of diclofenac epolamine make it well suited for topical use. In patients with acute soft tissue injuries treated with DETP, clinical data report an analgesic benefit within hours of the first application, and significant pain relief relative to placebo within 3 days. Moreover, DETP displayed tolerability comparable with placebo; the most common AEs were pruritus and other application site reactions. Review of published literature suggests that DETP is generally safe and well tolerated, clinically efficacious, and a rational treatment option for patients experiencing acute pain associated with strains, sprains, and contusions, and other localized painful conditions. PMID:21197326

3. Theoretical Topics in Particle Physics.

Roberts, Lee Alan

This dissertation contains three parts, each with a distinct topic. The three topics are (1) Higgs-boson decays at the superconducting super collider, (2) radiative corrections to the decay (pi)('o) (--->) (gamma)e('+)e(' -) and (3) generalised random paths in three and four dimensions. In Part I, distributions in cos(theta)(,lab), rapidity, energy, and p(,T) for the intermediate vector bosons resulting from p + p (--->) (H('o) (--->) W('+)W(' -), Z('o)Z('o)) + X and p + p (--->) (W('+)W('-),W('+)Z('o) + W('-)Z('o),Z('o)Z('o)) + X at SQRT.(s) = 40 TeV are compared for Higgs-boson masses of 5m(,w) and 7m(,w). The Higgs -boson-decay signal should be visible in the energy and p(,T) distributions of the vector bosons. In Part II, the radiative corrections to both the decay rate for (pi)('o) (--->) (gamma)e('+)e('-) and the differential spectrum in the invariant mass of the Dalitz pain for experiments with limited geometrical acceptance are calculated. In Part III, we introduce a generalised model for random paths (in arbitrary dimension) which smoothly interpolates between the standard paths (fermionic or bosonic) and the self-avoiding paths. An efficient Monte Carlo algorithm to simulate the model is presented along with some preliminary results for average length, intersection, overlap and mean square size of paths in three and four dimensions.

4. Symmetries and fundamental interactions—selected topics

Jungmann, Klaus P.

2014-06-01

High precision experiments at low energies on discrete and continuous symmetries offer the possibility to search for New Physics beyond the Standard Model. Examples are dedicated searches for violations of the C, P, CP and CPT as well as of Lorentz Invariance using matter and anti-matter. Atomic parity violation was not only essential in the past to verify the Standard Model, still today it has a potential to find Z' bosons, leptoquarks or dark matter. Electric Dipole Moments (EDMs) may provide clues to explain the matter-antimatter asymmetry in the universe. There is at present a some 4 standard deviations discrepancy between theory and experiment for the muon magnetic anomaly. At the same time while providing important information on physics beyond the Standard Model, new technology such as precise clocks is developed along with the experiments motivated by fundamental physics questions. This article summarizes an overview talk that was concerned primarily with a selection of topics from a very rich field, in particular such that were not covered otherwise at this conference.

5. [Topical treatments for psoriasis in 2009].

PubMed

Thielen, Anne-Marie; Laffitte, Emmanuel

2009-04-22

Psoriasis is a chronic inflammatory disease causing important physical and psychological morbidity. Topical treatments are the first choice therapeutic alternatives for mild and moderate psoriasis. We review the different topical treatment options for this common skin disease. PMID:19438087

6. Workplace Safety and Health Topics: Safety & Prevention

MedlinePlus

... message, please visit this page: About CDC.gov . Workplace Safety and Health Topics Industries & Occupations Hazards & Exposures Diseases & ... Pinterest Twitter YouTube NIOSH Homepage NIOSH A-Z Workplace Safety & Health Topics Publications and Products Programs Contact NIOSH ...

7. Topical Pain Relievers May Cause Burns

MedlinePlus

... For Consumers Home For Consumers Consumer Updates Topical Pain Relievers May Cause Burns Share Tweet Linkedin Pin it ... ts If you've ever rubbed a topical pain reliever—a cream, gel or other product applied to ...

8. True Color of Mars - Pathfinder Sol 24 at 4 PM

NASA Technical Reports Server (NTRS)

1999-01-01

The brownish gray sky as it would be seen by an observer on Mars in this four-frame, true color mosaic taken on sol 24 (at approximately 1610 LST). The twin peaks can be seen on the horizon. The sky near the sun is a pale blue color. Azimuth extent is 60o and elevation extent is approximately 12odegrees. A description of the techniques used to generate this color image from IMP data can be found in Maki et al., 1999 (see full reference in Image Note). Note: a calibrated output device is required accurately reproduce the correct colors.

Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The IMP was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal investigator.

9. Topical therapy for fungal infections.

PubMed

Kyle, Amber A; Dahl, Mark V

2004-01-01

Fungi often infect the skin surface and subsequently invade the stratum corneum to avoid being shed from the skin surface by desquamation. Pharmacologic agents applied to the surface of the skin in the form of creams, lotions, or sprays, readily penetrate into the stratum corneum to kill the fungi (fungicidal agents), or at least render them unable to grow or divide (fungistatic agents). Thus, topical therapies work well to rid the skin of topical fungi and yeasts. Azole drugs such as miconazole, clotrimazole, and ketoconazole are fungistatic, limiting fungal growth but depending on epidermal turnover to shed the still-living fungus from the skin surface. Allylamines and benzylamines such as terbinafine, naftifine, and butenafine are fungicidal, actually killing the fungal organisms. Fungicidal drugs are often preferred over fungistatic drugs for treatment of dermatophytic fungal infections, since treatment times as short as one application daily for 1 week are associated with high cure rates. Furthermore, patients often stop treatments when the skin appears healed, usually after about a week of treatment. If this short-term treatment is stopped, fungi recur more often when fungistatic, rather than fungicidal, drugs have been used. Yeast infections such as those caused by Candida albicans respond less well to allylamine drugs. The azole drugs are often preferred for these types of infections. Nail infections are difficult to cure with topical therapies because the infections usually occur under the nail instead of on top of it and products penetrate poorly, if at all, through the nail plate. Infections of hair follicles, nails, and widespread infections often require systemic treatments. Antifungal agents are compounded into many different types of vehicles. Patients often prefer to treat weeping infections with spray formulations. Most physicians prescribe branded products in cream or lotion bases. Cost is a factor dictating prescription choice, especially since

10. Toxicity and safety of topical sodium hypochlorite.

PubMed

Bruch, Mary K

2007-01-01

The safety and toxicity of sodium hypochlorite is reviewed with particular correlation to topical use. Since sodium hypochlorite is one of the most widely used chemicals in the environment, its safety has been established by long use and toxicity profile. This chapter reviews recent toxicology testing including routine systemic LD50, topical LD50, topical toxicology, irritation and sensitization. The resulting toxicity or safety profile clarifies the safe topical use of electrolytically produced sodium hypochlorite solution (ExSept, Amuchina 10%). PMID:17099299

11. Good and Bad Topics for Moral Education.

ERIC Educational Resources Information Center

Davidman, Patricia; And Others

This paper reports the opinions about moral topics expressed by 140 elementary and secondary student teachers, 49 in Indiana and 91 in California. Teachers' judgments of the suitability of topics were collected via a questionnaire containing 20 topics in two versions. The presentation consists of: (1) a description of the opinionnaire teachers…

12. Topics and Terms in Environmental Problems.

ERIC Educational Resources Information Center

Holum, John R.

This reference is an expanded glossary of topics and terms currently related to environmental problems. These topics and terms are associated with energy, air pollution, water pollution, wastes, and pesticides. Included are 239 main entries ranging from acaricide to weathering. Each entry briefly describes the topic or term and often presents a…

13. TOPICAL REVIEW: Highly charged ions

Gillaspy, J. D.

2001-10-01

This paper reviews some of the fundamental properties of highly charged ions, the methods of producing them (with particular emphasis on table-top devices), and their use as a tool for both basic science and applied technology. Topics discussed include: charge dependence and scaling laws along isoelectronic or isonuclear sequences (for wavefunction size or Bohr radius, ionization energy, dipole transition energy, relativistic fine structure, hyperfine structure, Zeeman effect, Stark effect, line intensities, linewidths, strength of parity violation, etc), changes in angular momentum coupling schemes, selection rules, interactions with surfaces, electron-impact ionization, the electron beam ion trap (EBIT), ion accelerators, atomic reference data, cosmic chronometers, laboratory x-ray astrophysics, vacuum polarization, solar flares, ion implantation, ion lithography, ion microprobes (SIMS and x-ray microscope), nuclear fusion diagnostics, nanotechnology, quantum computing, cancer therapy and biotechnology.

14. [Regulatory requirements for topical preparations].

PubMed

Wohlrab, J; Klauck, D; Savtcheva, E

2014-03-01

Professional use of topical treatment in dermatological practice requires not only knowledge about the pharmacological properties, efficacy, safety and pharmaceutical quality of a preparation, but also about its regulatory classification. The latter essentially determines the physician's prescription practice and therapeutic freedom. The regulatory framework with which one is confronted unfortunately lacks transparency. It regulates not only the prescribability and reimbursability of proprietary medicinal products and extemporaneous preparations, but also the obligation to give information as well as the details of liability of both the prescriber (physician) and the manufacturer (pharmaceutical company or pharmacist). The prescriber needs to be aware of to what extent the pharmacist has the possibility and even obligation to change the prescribed preparation. In some cases this can directly affect the therapeutic concept of the physician and even impair the effectiveness and safety of the chosen therapy. PMID:24622851

15. [Topical therapy in erectile dysfunction].

PubMed

Floth, A

2000-01-01

All forms of pharmacological therapy result in a relaxation of the corporeal smooth muscle. Intracorporeal injection of vasoactive drugs was introduced around 15 years ago and still is the most effective therapy in erectile dysfunction. Resulting in a consistent success rate of 70-80% this form of therapy will find numerous applications, even after the introduction of effective oral agents such as sildenafil. Prostaglandin E1 and--less frequently used--the combination of papaverine and phentolamine are the mainstay of intracorporeal injection therapy. Intraurethral prostaglandin (MUSE) has recently become available and is somewhat less effective than injection therapy. Externally applied drugs (nitroglycerin paste on the penile shaft and minoxidil solution on the glans penis) have not succeeded in the long run. Vacuum erection devices represent a form of physical topical therapy that is very versatile and also effective but rather infrequently applied. PMID:10746290

16. Topical Immunotherapy in Alopecia Areata

PubMed Central

Singh, Gurcharan; Lavanya, MS

2010-01-01

Alopecia Areata (AA) is a common non-scarring alopecia directed against the anagenic hair follicle. Various treatment modalities have been used for the treatment of severe AA. Topical immunotherapy is the best documented treatment so far for severe and refractory AA. Dinitrochlorobenzene (DNCB), squaric acid dibutylester (SADBE), and diphencyprone (DPCP) are the contact allergens used for this purpose. DNCB has been found to be mutagenic by the Ames test and is largely replaced by DPCP and SADBE. DPCP and SADBE are both known to be non-mutagenic compounds and have comparable efficacy results and relapse rates. SADBE requires special solvents and additives to maintain its potency and is more expensive than the rest. DPCP has a response rate varying from 60% in severe Alopecia Areata to 17% in patients with alopecia totalis or universalis, and shows about 88 to 100% high response rate in patients with patchy Alopecia Areata. PMID:21188022

17. Judging Books by Their Covers: A Cover Art Experiment.

ERIC Educational Resources Information Center

Sullivan, Edward T.

1998-01-01

A group of 21 young adults (11-17) were asked to rate books by their cover art only and write explanations for their ratings. Discusses ratings and their rationales and concludes that the participants expected a cover to give them an idea of what a story was about. Includes a list of the books evaluated. (PEN)

18. Current Topics in Epilepsy Surgery.

PubMed

Usui, Naotaka

2016-05-15

This article reviews the current topics in the field of epilepsy surgery. Each type of epilepsy is associated with a different set of questions and goals. In mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS), postoperative seizure outcome is satisfactory. A recent meta-analysis revealed superior seizure outcome after anterior temporal lobectomy compared with selective amygdalohippocampectomy; in terms of cognitive outcome; however, amygdalohippocampectomy may be beneficial. In temporal lobe epilepsy with normal magnetic resonance imaging (MRI), postoperative seizure outcome is not as favorable as it is in MTLE with HS; further improvement of seizure outcome in these cases is necessary. Focal cortical dysplasia is the most common substrate in intractable neocortical epilepsy, especially in children, as well as in MRI-invisible neocortical epilepsy. Postoperative seizure-free outcome is approximately 60-70%; further diagnostic and therapeutic improvement is required. Regarding diagnostic methodology, an important topic currently under discussion is wideband electroencephalogram (EEG) analysis. Although high-frequency oscillations and ictal direct current shifts are considered important markers of epileptogenic zones, the clinical significance of these findings should be clarified further. Regarding alternatives to surgery, neuromodulation therapy can be an option for patients who are not amenable to resective surgery. In addition to vagus nerve stimulation, intracranial stimulation such as responsive neurostimulation or anterior thalamic stimulation is reported to have a modest seizure suppression effect. Postoperative management such as rehabilitation and antiepileptic drug (AED) management is important. It has been reported that postoperative rehabilitation improves postoperative employment status. Pre- and post-operative comprehensive care is mandatory for postoperative improvement of quality of life. PMID:26984452

19. Current Topics in Epilepsy Surgery

PubMed Central

USUI, Naotaka

2016-01-01

This article reviews the current topics in the field of epilepsy surgery. Each type of epilepsy is associated with a different set of questions and goals. In mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS), postoperative seizure outcome is satisfactory. A recent meta-analysis revealed superior seizure outcome after anterior temporal lobectomy compared with selective amygdalohippocampectomy; in terms of cognitive outcome; however, amygdalohippocampectomy may be beneficial. In temporal lobe epilepsy with normal magnetic resonance imaging (MRI), postoperative seizure outcome is not as favorable as it is in MTLE with HS; further improvement of seizure outcome in these cases is necessary. Focal cortical dysplasia is the most common substrate in intractable neocortical epilepsy, especially in children, as well as in MRI-invisible neocortical epilepsy. Postoperative seizure-free outcome is approximately 60–70%; further diagnostic and therapeutic improvement is required. Regarding diagnostic methodology, an important topic currently under discussion is wideband electroencephalogram (EEG) analysis. Although high-frequency oscillations and ictal direct current shifts are considered important markers of epileptogenic zones, the clinical significance of these findings should be clarified further. Regarding alternatives to surgery, neuromodulation therapy can be an option for patients who are not amenable to resective surgery. In addition to vagus nerve stimulation, intracranial stimulation such as responsive neurostimulation or anterior thalamic stimulation is reported to have a modest seizure suppression effect. Postoperative management such as rehabilitation and antiepileptic drug (AED) management is important. It has been reported that postoperative rehabilitation improves postoperative employment status. Pre- and post-operative comprehensive care is mandatory for postoperative improvement of quality of life. PMID:26984452

20. Statistical analysis of multivariate atmospheric variables. [cloud cover

NASA Technical Reports Server (NTRS)

Tubbs, J. D.

1979-01-01

Topics covered include: (1) estimation in discrete multivariate distributions; (2) a procedure to predict cloud cover frequencies in the bivariate case; (3) a program to compute conditional bivariate normal parameters; (4) the transformation of nonnormal multivariate to near-normal; (5) test of fit for the extreme value distribution based upon the generalized minimum chi-square; (6) test of fit for continuous distributions based upon the generalized minimum chi-square; (7) effect of correlated observations on confidence sets based upon chi-square statistics; and (8) generation of random variates from specified distributions.

1. Design, Development, and Psychometric Analysis of a General, Organic, and Biological Chemistry Topic Inventory Based on the Identified Main Chemistry Topics Relevant to Nursing Clinical Practice

ERIC Educational Resources Information Center

Brown, Corina E.

2013-01-01

This two-stage study focused on the undergraduate nursing course that covers topics in general, organic, and biological (GOB) chemistry. In the first stage, the central objective was to identify the main concepts of GOB chemistry relevant to the clinical practice of nursing. The collection of data was based on open-ended interviews of both nursing…

2. Conference report: hot topics in antibody-drug conjugate development.

PubMed

Thudium, Karen; Bilic, Sanela

2013-12-01

3. Advances in drilling covered at conference in Southeast Asia

SciTech Connect

Not Available

1993-02-01

Recent advances in drilling technology include new applications for various polymer-based drilling fluids, an analytical evaluation of certain gas control additives for light cement slurries, the use of a new wellhead connector, and the development of a unique completion tool for slim hole wells. This paper reports on these topics which were covered in several papers prepared for the Offshore South East Asia 9th Conference and Exhibition held Dec. 1-4, 1992, in Singapore. Drilling fluids formulated with partially hydrolyzed polyacrylamide were used successfully and economically to control well bore problems in a development drilling program in southeast Asia. Another paper presented results on the use of various cationic and anionic materials to control shale stability problems common to areas offshore western Australia. Another paper presented results of an evaluation of five common additives used to control gas migration problems in light-weight cements. In addition to these fluid topics, recent mechanical developments were covered.

4. Midwest Cover Crops Field Guide

Technology Transfer Automated Retrieval System (TEKTRAN)

Producers who want to prevent soil erosion, improve nutrient cycling, sustain their soils, and protect/maintain the environment have been returning to a very old practice: planting cover crops. Cover crops are effective tools for reducing soil erosion and increasing nutrient recycling on farmlands, ...

5. Cover crops and vegetable rotations

Technology Transfer Automated Retrieval System (TEKTRAN)

Farmers have long known that winter cover crops can decrease soil erosion, increase soil organic matter and fertility, and provide a beneficial impact on the following crop, but it is not always known which cover crop will provide the best results for a specific region and cropping system. Research...

6. High plains cover crop research

Technology Transfer Automated Retrieval System (TEKTRAN)

Some recent statements have been made about the benefits of growing cover crops in mixtures as compared with single-species plantings of cover crops. Those stated benefits have included greatly reduced water use, enhanced soil microbiological activity, increased biomass productivity, and enhanced wa...

7. Set covering, partition and packing

SciTech Connect

Hulme, B.L.; Baca, L.S.

1984-03-01

Set covering problems are known to be solvable by Boolean algebraic methods. This report shows that set partition and set packing problems can be solved by the same algebraic methods because these problems can be converted into covering problems. Many applications are possible including security patrol assignment which is used as an example.

8. Identifying Topics in Microblogs Using Wikipedia.

PubMed

Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

2016-01-01

Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail. PMID:26991442

9. Identifying Topics in Microblogs Using Wikipedia

PubMed Central

Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

2016-01-01

Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail. PMID:26991442

10. Automatic design of magazine covers

Jahanian, Ali; Liu, Jerry; Tretter, Daniel R.; Lin, Qian; Damera-Venkata, Niranjan; O'Brien-Strain, Eamonn; Lee, Seungyon; Fan, Jian; Allebach, Jan P.

2012-03-01

In this paper, we propose a system for automatic design of magazine covers that quantifies a number of concepts from art and aesthetics. Our solution to automatic design of this type of media has been shaped by input from professional designers, magazine art directors and editorial boards, and journalists. Consequently, a number of principles in design and rules in designing magazine covers are delineated. Several techniques are derived and employed in order to quantify and implement these principles and rules in the format of a software framework. At this stage, our framework divides the task of design into three main modules: layout of magazine cover elements, choice of color for masthead and cover lines, and typography of cover lines. Feedback from professional designers on our designs suggests that our results are congruent with their intuition.

11. Public understanding of geoscientific topics

Münch, Ute; Lauterjung, Jörn

2014-05-01

Geoscientific topics and their consequences for the society are becoming more and more important for our daily life. Natural hazards such as flood and storm or the consequences of the climate change are urgent tasks and great challenges we have to tackle. Cascading natural hazards or environmental risks, can't be evaluated as single events by one scientific discipline, they rather need the expertise of different experts. The same applies for slowly progressive processes such as the climate change and its different aftereffects. More than ever politicians, decision makers, but also the public are asking for comprehensive background information and data to discuss activity options and to develop sustainable solutions. The improvement of public knowledge about science, their assets and drawbacks, chances and risks is getting crucial. To paint a comprehensive picture of different factors, correlations and dependencies the pooling of expertise is required. Thus eight research centres of the research field "Earth and Environment" of the Helmholtz-Association, Germany's largest scientific research organisation are currently building up a knowledge platform. Scientists of different disciplines will provide background information and explain their latest findings in an understandable way. Infographics, maps and animations will be applied to simplify and interpret complicated facts and findings. In addition to the web presence target group-specific products and activities will be organized. To meet the expectations of the different stakeholders an intensive dialog is aspired: round table discussions, exhibitions in museums and public places, tweeds are envisaged. In the beginning the partners will concentrate on the topics "consequences of the climate change", "pollutant dispersion" and "natural hazards/meteorological extreme events". The project is called Earth System Knowledge Platform (ESKP) coordinated by the German Research Centre for Geosciences (GFZ) and the Helmholtz

12. Calabi-Yau orbifolds and torus coverings

Hanany, Amihay; Jejjala, Vishnu; Ramgoolam, Sanjaye; Seong, Rak-Kyeong

2011-09-01

The theory of coverings of the two-dimensional torus is a standard part of algebraic topology and has applications in several topics in string theory, for example, in topological strings. This paper initiates applications of this theory to the counting of orbifolds of toric Calabi-Yau singularities, with particular attention to Abelian orbifolds of {mathbb{C}^D} . By doing so, the work introduces a novel analytical method for counting Abelian orbifolds, verifying previous algorithm results. One identifies a p-fold cover of the torus {mathbb{T}^{D - 1}} with an Abelian orbifold of the form {{{{mathbb{C}^D}}} left/ {{{mathbb{Z}_p}}} right.} , for any dimension D and a prime number p. The counting problem leads to polynomial equations modulo p for a given Abelian subgroup of S D , the group of discrete symmetries of the toric diagram for {mathbb{C}^D} . The roots of the polynomial equations correspond to orbifolds of the form {{{{mathbb{C}^D}}} left/ {{{mathbb{Z}_p}}} right.} , which are invariant under the corresponding subgroup of S D . In turn, invariance under this subgroup implies a discrete symmetry for the corresponding quiver gauge theory, as is clearly seen by its brane tiling formulation.

13. Topics in cancer risk assessment.

PubMed Central

Olin, S S; Neumann, D A; Foran, J A; Scarano, G J

1997-01-01

The estimation of carcinogenic risks from exposure to chemicals has become an integral part of the regulatory process in the United States within the past decade. With it have come considerable controversy and debate over the scientific merits and shortcomings of the methods and their impact on risk management decisions. In this paper we highlight selected topics of current interest in the debate. As an indication of the level of public concern, we note the major recent reports on risk assessment from the National Academy of Sciences and the U.S Environmental Protection Agency's proposed substantial revisions to its Guidelines for Carcinogen Risk Assessment. We identify and briefly frame several key scientific issues in cancer risk assessment, including the growing recognition of the importance of understanding the mode of action of carcinogenesis in experimental animals and in humans, the methodologies and challenges in quantitative extrapolation of cancer risks, and the question of how to assess and account for human variability in susceptibility to carcinogens. In addition, we discuss initiatives in progress that may fundamentally alter the carcinogenesis testing paradigm. PMID:9114281

14. Decision Point 1 Topical Report

SciTech Connect

Yablonsky, Al; Barsoumian, Shant; Legere, David

2013-05-01

This Topical Report addresses accomplishments achieved during Phase 2a of the SkyMine® Carbon Mineralization Pilot Project. The primary objectives of this project are to design, construct, and operate a system to capture CO2 from a slipstream of flue gas from a commercial coal-fired cement kiln, convert that CO2 to products having commercial value (i.e., beneficial use), show the economic viability of the CO2 capture and conversion process, and thereby advance the technology to the point of readiness for commercial scale demonstration and proliferation. The overall process is carbon negative, resulting in mineralization of CO2 that would otherwise be released into the atmosphere. The project will also substantiate market opportunities for the technology by sales of chemicals into existing markets, and identify opportunities to improve technology performance and reduce costs at the commercial scale. The project is being conducted in two phases. The primary objectives of Phase 1 were to elaborate proven SkyMine® process chemistry to commercial pilot-scale operation and complete the preliminary design for the pilot plant to be built and operated in Phase 2, complete a NEPA evaluation, and develop a comprehensive carbon life cycle analysis. The objective of the current Phase (2a) is to complete the detailed design of the pilot plant to be built in Phase 2b.

15. Editors' preface for the topical issue on Seven papers on Noncommutative Geometry and Operator Algebras

Guido, Daniele; Landi, Giovanni; Vassout, Stéphane

2016-07-01

This topical issue grew out of the International Conference "Noncommutative Geometry and Applications" held 16-21 June 2014 at Villa Mondragone, Frascati (Roma). The main purpose of the conference was to have a unified view of different incarnations of noncommutative geometry and its applications. The seven papers collected in the present topical issue represent a good sample of the topics covered at the workshop. The conference itself was one of the climaxes of the Franco-Italian project GREFI-GENCO, which was initiated in 2007 by CNRS and INDAM to promote and enhance collaboration and exchanges between French and Italian researchers in the area of noncommutative geometry.

16. Selected topics of fluid mechanics

USGS Publications Warehouse

Kindsvater, Carl E.

1958-01-01

the Euler, Froude, Reynolds, Weber, and Cauchy numbers are defined as essential tools for interpreting and using experimental data. The derivations of the energy and momentum equations are treated in detail. One-dimensional equations for steady nonuniform flow are developed, and the restrictions applicable to the equations are emphasized. Conditions of uniform and gradually varied flow are discussed, and the origin of the Chezy equation is examined in relation to both the energy and the momentum equations. The inadequacy of all uniform-flow equations as a means of describing gradually varied flow is explained. Thus, one of the definitive problems of river hydraulics is analyzed in the light of present knowledge. This report is the outgrowth of a series of short schools conducted during the spring and summer of 1953 for engineers of the Surface Water Branch, Water Resources Division, U. S. Geological Survey. The topics considered are essentially the same as the topics selected for inclusion in the schools. However, in order that they might serve better as a guide and outline for informal study, the arrangement of the writer's original lecture notes has been considerably altered. The purpose of the report, like the purpose of the schools which inspired it, is to build a simple but strong framework of the fundamentals of fluid mechanics. It is believed that this framework is capable of supporting a detailed analysis of most of the practical problems met by the engineers of the Geological Survey. It is hoped that the least accomplishment of this work will be to inspire the reader with the confidence and desire to read more of the recent and current technical literature of modern fluid mechanics.

17. Microcirculatory effect of topical vapocoolants

PubMed Central

Galdyn, Izabela; Swanson, Edward; Gordon, Chad; Kwiecien, Grzegorz; Bena, James; Siemionow, Maria; Zins, James

2015-01-01

BACKGROUND: Vapocoolant sprays are commonly used to minimize pain following minor interventions such as venipuncture, shave biopsy or needle insertion. Although these sprays have been widely used in clinical practice, little is known about their effect on microcirculation or cutaneous blood flow. OBJECTIVE: To evaluate the real-time effect of a topical vapocoolant using a well-established, rat cremaster muscle microcirculatory model, allowing direct measurement of changes in vessel diameter, capillary density and leukocyte behaviour. METHODS: Fifty rats were divided into a control and four experimental groups: group 1: 4 s spray with vapocoolant at 18 cm distance; group 2: 10 s spray at 18 cm distance; group 3: 4 s spray at 8 cm distance; and group 4: 10 s spray at 8 cm distance. Vessel diameters, capillary density and leukocyte behaviour were monitored for 1 h thereafter. Muscle was harvested for immunohistochemistry analysis of proangiogenic markers (vascular endothelial growth factor and von Willebrand factor), leukocyte behaviour markers (E-selectin, vascular cell adhesion molecule, intercellular adhesion molecule), pimonidazole-hypoxia staining and ApopTag (Millipore, USA) staining for apoptosis. Gene expression for inflammatory markers (interleukin [IL]-1β, IL-2, IL-4, IL-6, IL-10, tumour necrosis factor-alpha and interferon-gamma) was evaluated using polymerase chain reaction and myeloperoxidase assay for inflammation was performed. RESULTS: The use of refrigerant spray decreased vessel diameter and capillary density initially, although none of these decreases were statistically significant. Polymerase chain reaction showed no significant changes. The myeloperoxidase assay showed statistically significant increase in myeloperoxidase activity in groups 2, 3 and 4. Immunohistochemistry was negative for angiogenic and proinflammatory markers. CONCLUSIONS: The lack of statistically significant changes in vessel diameter and inflammatory markers corroborated the

18. Topics in topological band systems

Huang, Zhoushen

The discovery of integer quantum Hall effect and its subsequent theoretical formulation heralded a new paradigm of thinking in condensed matter physics, which has by now blossomed into the rapidly growing field of topological phases. In this work we investigate several mutually related topics in the framework of topological band theory. In Chapter 2, we study solutions to boundary states on a lattice and see how they are related to the bulk topology. To elicit a real space manifestation of the non-trivial topology, the presence of a physical edge is not strictly necessary. We study two other possibilities, namely the entanglement spectrum associated with an imaginary spatial boundary, and the localization centers of Wannier functions, in Chapters 3,4, and 5. Topological classification through discrete indices is so far possible only for systems described by pure quantum states---in the existing scheme, quantization is lost for systems in mixed states. In Chapter 6, we present a program through which discrete topological indices can be defined for topological band systems at finite temperature, based on Uhlmann's parallel transport of density matrices. The potential of topologocal insulators in realistic applications lies in the existence of Dirac nodes on its surface spectrum. Dirac physics, however, is not exclusive to TI surfaces. In a recently discovered class of materials known as Weyl semimetals, energy nodes which emit linear dispersions also occur in the bulk material. In Chapter 7, we study the possibility of resonance states induced by localized impurities near the nodal energy in Weyl semimetals, which will help us in understanding the stability of density-of-state suppression at the energy nodes. Finally, in Chapter 8, we apply the topological characterization developed for noninteracting particles to a class of interacting spin models in 3D, which are generalizations of Kitaev's honeycomb model, and identify several exotic quantum phases such as spin

19. Usage-Oriented Topic Maps Building Approach

Ellouze, Nebrasse; Lammari, Nadira; Métais, Elisabeth; Ben Ahmed, Mohamed

In this paper, we present a collaborative and incremental construction approach of multilingual Topic Maps based on enrichment and merging techniques. In recent years, several Topic Map building approaches have been proposed endowed with different characteristics. Generally, they are dedicated to particular data types like text, semi-structured data, relational data, etc. We note also that most of these approaches take as input monolingual documents to build the Topic Map. The problem is that the large majority of resources available today are written in various languages, and these resources could be relevant even to non-native speakers. Thus, our work is driven towards a collaborative and incremental method for Topic Map construction from textual documents available in different languages. To enrich the Topic Map, we take as input a domain thesaurus and we propose also to explore the Topic Map usage which means available potential questions related to the source documents.

20. LANDFILL CONTAINMENT AND COVER SYSTEMS

EPA Science Inventory

The U.S. Environmental Protection Agency through its research and field experiences has developed control strategies for hazardous and municipal solid waste landfills and surface impoundments. hese control strategies include liner and cover systems. he liner systems include doubl...

1. Tracking topic birth and death in LDA.

SciTech Connect

Wilson, Andrew T.; Robinson, David Gerald

2011-09-01

Most topic modeling algorithms that address the evolution of documents over time use the same number of topics at all times. This obscures the common occurrence in the data where new subjects arise and old ones diminish or disappear entirely. We propose an algorithm to model the birth and death of topics within an LDA-like framework. The user selects an initial number of topics, after which new topics are created and retired without further supervision. Our approach also accommodates many of the acceleration and parallelization schemes developed in recent years for standard LDA. In recent years, topic modeling algorithms such as latent semantic analysis (LSA)[17], latent Dirichlet allocation (LDA)[10] and their descendants have offered a powerful way to explore and interrogate corpora far too large for any human to grasp without assistance. Using such algorithms we are able to search for similar documents, model and track the volume of topics over time, search for correlated topics or model them with a hierarchy. Most of these algorithms are intended for use with static corpora where the number of documents and the size of the vocabulary are known in advance. Moreover, almost all current topic modeling algorithms fix the number of topics as one of the input parameters and keep it fixed across the entire corpus. While this is appropriate for static corpora, it becomes a serious handicap when analyzing time-varying data sets where topics come and go as a matter of course. This is doubly true for online algorithms that may not have the option of revising earlier results in light of new data. To be sure, these algorithms will account for changing data one way or another, but without the ability to adapt to structural changes such as entirely new topics they may do so in counterintuitive ways.

2. Flammable gas project topical report

SciTech Connect

Johnson, G.D.

1997-01-29

The flammable gas safety issue was recognized in 1990 with the declaration of an unreviewed safety question (USQ) by the U. S. Department of Energy as a result of the behavior of the Hanford Site high-level waste tank 241-SY-101. This tank exhibited episodic releases of flammable gas that on a couple of occasions exceeded the lower flammability limit of hydrogen in air. Over the past six years there has been a considerable amount of knowledge gained about the chemical and physical processes that govern the behavior of tank 241-SY-1 01 and other tanks associated with the flammable gas safety issue. This report was prepared to provide an overview of that knowledge and to provide a description of the key information still needed to resolve the issue. Items covered by this report include summaries of the understanding of gas generation, retention and release mechanisms, the composition and flammability behavior of the gas mixture, the amounts of stored gas, and estimated gas release fractions for spontaneous releases. `Me report also discusses methods being developed for evaluating the 177 tanks at the Hanford Site and the problems associated with these methods. Means for measuring the gases emitted from the waste are described along with laboratory experiments designed to gain more information regarding rates of generation, species of gases emitted and modes of gas storage and release. Finally, the process for closing the USQ is outlined as are the information requirements to understand and resolve the flammable gas issue.

3. Topical Products for the Aging Face.

PubMed

McCook, John P

2016-07-01

This article focuses on nonprescription home-use topical treatment technologies for the aging face and is intended to serve as a guide for the core cosmeceutical technologies currently used and to help educate and assist the selection of topical antiaging products by the professional staff and their patients. Antiaging topical treatments for patient home use should be nonirritating, compatible with the patient skin type, effective, and complementary to surgical and minimally invasive office procedures, and aesthetically elegant. New topical antiaging technologies, formulated as monotherapy or as combinations with well-known cosmeceuticals, should present adequate clinical studies to support their selection for use. PMID:27363774

4. Updates of Topical and Local Anesthesia Agents.

PubMed

Boyce, Ricardo A; Kirpalani, Tarun; Mohan, Naveen

2016-04-01

As described in this article, there are many advances in topical and local anesthesia. Topical and local anesthetics have played a great role in dentistry in alleviating the fears of patients, eliminating pain, and providing pain control. Many invasive procedures would not be performed without the use and advances of topical/local anesthetics. The modern-day dentist has the responsibility of knowing the variety of products on the market and should have at least references to access before, during, and after treatment. This practice ensures proper care with topical and local anesthetics for the masses of patients entering dental offices worldwide. PMID:27040295

5. The treatment of rosacea with topical ivermectin.

PubMed

Ali, S T; Alinia, H; Feldman, S R

2015-04-01

The treatment of rosacea is challenging because several pathophysiologic processes may be involved, including neurovascular dysregulation and alterations in innate immune status. Demodex mites may play a role in the latter mechanism. Topical ivermectin is a new therapeutic modality which demonstrates antiparasitic and anti-inflammatory properties. This article reviews published evidence related to the efficacy and safety of topical ivermectin. PubMed was utilized to search for key words "topical ivermectin", "ivermectin cream" and "rosacea". Three clinical trials were found that studied topical ivermectin as a treatment option for rosacea. Ivermectin was effective, safe and well tolerated. PMID:26020066

6. Extensive visual loss with topical facial steroids.

PubMed

Aggarwal, R K; Potamitis, T; Chong, N H; Guarro, M; Shah, P; Kheterpal, S

1993-01-01

Steroid creams applied topically to the skin are routinely used in the treatment of many dermatoses. Their use on the face in severe atopic eczema is relatively common. We report a series of three patients who whilst using topical facial steroids developed advanced glaucoma. A further two cases of ocular hypertension secondary to topical facial steroids are also described. This is the first series of cases to be reported demonstrating the potentially blinding complications of topical facial steroids. Recommendations are made with regard to screening such patients for glaucoma. PMID:8287990

7. Land-cover change detection

USGS Publications Warehouse

Chen, Xuexia; Giri, Chandra; Vogelmann, James

2012-01-01

Land cover is the biophysical material on the surface of the earth. Land-cover types include grass, shrubs, trees, barren, water, and man-made features. Land cover changes continuously.  The rate of change can be either dramatic and abrupt, such as the changes caused by logging, hurricanes and fire, or subtle and gradual, such as regeneration of forests and damage caused by insects (Verbesselt et al., 2001).  Previous studies have shown that land cover has changed dramatically during the past sevearal centuries and that these changes have severely affected our ecosystems (Foody, 2010; Lambin et al., 2001). Lambin and Strahlers (1994b) summarized five types of cause for land-cover changes: (1) long-term natural changes in climate conditions, (2) geomorphological and ecological processes, (3) human-induced alterations of vegetation cover and landscapes, (4) interannual climate variability, and (5) human-induced greenhouse effect.  Tools and techniques are needed to detect, describe, and predict these changes to facilitate sustainable management of natural resources.

8. Topical issues in venous thromboembolism.

PubMed

Abad Rico, José Ignacio; Llau Pitarch, Juan Vicente; Páramo Fernández, José Antonio

2010-12-14

Despite clear guidelines and the availability of effective treatments, venous thromboembolism (VTE) remains relatively common, particularly in the hospital setting. This paper reviews topical issues in VTE, in terms of treatments, data and guidelines. Existing anticoagulants have several limitations. Bleeding risk is a concern with all anticoagulants. Vitamin K antagonists are the mainstay of oral anticoagulant therapy, but they are limited by the need for frequent monitoring. Unfractionated heparin (UFH) is limited by an inconvenient route of administration (continuous intravenous infusion) and a higher risk of heparin-induced thrombocytopenia and bleeding compared with low molecular weight heparins (LMWH). LMWH have a more predictable pharmacokinetic profile and greater bioavailability than UFH, which permits weight-adjusted LMWH dosing without the need for monitoring in most patients. LMWH also have a more convenient dosing strategy than UFH (once-daily subcutaneous injection). Fondaparinux is a selective inhibitor of factor Xa and, like LMWH, does not require monitoring. The efficacy of fondaparinux in long-term VTE treatment remains to be established. The optimal time to initiate thromboprophylaxis in patients undergoing orthopaedic surgery remains controversial. Initiating thromboprophylaxis just before or soon after surgery (the 'just-in-time' strategy) achieves better thromboprophylaxis but could increase the risk of bleeding complications. Balancing the need for extended thromboprophylaxis after major surgery with the need to minimize bleeding remains an important consideration. Despite clear guidelines, thromboprophylaxis is widely underused, particularly in medical patients, in whom rates as low as 28% have been reported. Electronic alert systems may be of value for increasing the use of adequate thromboprophylaxis. The use of different definitions of VTE and bleeding in clinical trials, together with missing venography data, conflicting guidelines in

9. Topics in elementary particle physics

Jin, Xiang

The author of this thesis discusses two topics in elementary particle physics: n-ary algebras and their applications to M-theory (Part I), and functional evolution and Renormalization Group flows (Part II). In part I, Lie algebra is extended to four different n-ary algebraic structure: generalized Lie algebra, Filippov algebra, Nambu algebra and Nambu-Poisson tensor; though there are still many other n-ary algebras. A natural property of Generalized Lie algebras — the Bremner identity, is studied, and proved with a totally different method from its original version. We extend Bremner identity to n-bracket cases, where n is an arbitrary odd integer. Filippov algebras do not focus on associativity, and are defined by the Fundamental identity. We add associativity to Filippov algebras, and give examples of how to construct Filippov algebras from su(2), bosonic oscillator, Virasoro algebra. We try to include fermionic charges into the ternary Virasoro-Witt algebra, but the attempt fails because fermionic charges keep generating new charges that make the algebra not closed. We also study the Bremner identity restriction on Nambu algebras and Nambu-Poisson tensors. So far, the only example 3-algebra being used in physics is the BLG model with 3-algebra A4, describing two M2-branes interactions. Its extension with Nambu algebra, BLG-NB model, is believed to describe infinite M2-branes condensation. Also, there is another propose for M2-brane interactions, the ABJM model, which is constructed by ordinary Lie algebra. We compare the symmetry properties between them, and discuss the possible approaches to include these three models into a grand unification theory. In Part II, we give an approximate solution for Schroeder's equations, based on series and conjugation methods. We use the logistic map as an example, and demonstrate that this approximate

10. Topical antifungals for seborrhoeic dermatitis

PubMed Central

Okokon, Enembe O; Verbeek, Jos H; Ruotsalainen, Jani H; Ojo, Olumuyiwa A; Bakhoya, Victor Nyange

2015-01-01

Background Seborrhoeic dermatitis is a chronic inflammatory skin condition that is distributed worldwide. It commonly affects the scalp, face and flexures of the body. Treatment options include antifungal drugs, steroids, calcineurin inhibitors, keratolytic agents and phototherapy. Objectives To assess the effects of antifungal agents for seborrhoeic dermatitis of the face and scalp in adolescents and adults. A secondary objective is to assess whether the same interventions are effective in the management of seborrhoeic dermatitis in patients with HIV/AIDS. Search methods We searched the following databases up to December 2014: the Cochrane Skin Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (2014, Issue 11), MEDLINE (from 1946), EMBASE (from 1974) and Latin American Caribbean Health Sciences Literature (LILACS) (from 1982). We also searched trials registries and checked the bibliographies of published studies for further trials. Selection criteria Randomised controlled trials of topical antifungals used for treatment of seborrhoeic dermatitis in adolescents and adults, with primary outcome measures of complete clearance of symptoms and improved quality of life. Data collection and analysis Review author pairs independently assessed eligibility for inclusion, extracted study data and assessed risk of bias of included studies. We performed fixed-effect meta-analysis for studies with low statistical heterogeneity and used a random-effects model when heterogeneity was high. Main results We included 51 studies with 9052 participants. Of these, 45 trials assessed treatment outcomes at five weeks or less after commencement of treatment, and six trials assessed outcomes over a longer time frame. We believe that 24 trials had some form of conflict of interest, such as funding by pharmaceutical companies. Among the included studies were 12 ketoconazole trials (N = 3253), 11 ciclopirox trials (N = 3029), two lithium trials (N = 141

11. [Current topics on infectious diseases].

PubMed

Miyara, Takayuki

2013-02-01

In April 2012, the Japanese Health authority recommended the establishment of an inter-hospital connection and cooperation system for infection control in each local area. This system is aimed at improving the risk of hospital-related infection in each local area units. An important role of the system is monitoring the trend of drug-resistant bacteria and detecting outbreaks; therefore, development of a bacterial laboratory system is a major subject for participating hospitals. Increasingly drug-resistant bacteria, such as extended-spectrum beta-lactamase-producing bacteria, MRSA, especially relatively high MIC strains against vancomycin (2 microg/ml), multi-drug resistant Gram-negative bacteria including Pseudomonas aeruginosa are serious issues for public health. The isolating ratio of these drug-resistant bacteria is different among hospitals even in the same local area. This is the point of organizing an inter-hospital infection control system. Last year, The Japanese Society for Respiratology developed management guidelines for Nursing Home and Health Care facility-associated pneumonia(NHCAP). This Japanese guideline and USA guidelines for similar situations state almost the same position. Namely, such pneumonia patients should be treated empirically with combination antibiotics covering drug-resistant bacteria, especially for MRSA and P. aeruginosa; however, in spite of this strengthened antibiotic coverage policy, one multicenter cohort study showed that guideline-based strengthened therapy increased the mortality of patients. The author drew the conclusion that too strong combination antibiotic therapy may be harmful to elderly patients. From these results, it should be considered that the causative agents of pneumonia cannot be determined from respiratory specimens so exactly, because the specimens include merely colonized bacteria and also anaerobic causative agents. PMID:23672088

12. Thermal properties for vegetation cover

Aleksyutina, D.; Motenko, R.

2011-12-01

Different samples of undisturbed vegetation cover were studied under laboratory conditions. Samples were collected from New Chara city, north of the Chita region. Vegetation cover in this area is represented by moss, lichen and tussock growth. Thermal properties were investigated by the I-st type regular mode method (a-calorimeter), the freezing temperature was studied by cryoscopic methods. The dry density of sampled specimens varies from 0.04 to 0.24 g/cm3, and humidity varies from 250 to 375 percent. The freezing temperature depends on moisture content and varies from -0.2 to 0 degrees centigrade. The vegetation cover had low thermal conductivities which varies from 0.05 to 0.46 W/(m*K) in unfrozen conditions, and from 0.07 to 1.14 W/(m*K) in frozen conditions, according to density and moisture content. Diffusivity of samples varies from 0.073*10-6 to 0.114*10-6 m2/s in thawed conditions, and from 0.174*10-6 to 0.584*10-6 m2/s in frozen conditions. The sod (bottom of vegetation cover) had relatively high thermal properties. Thermal properties of vegetation cover and peat (turf) were compared. The thermal conductivity of peat was much higher than thermal conductivity of vegetation cover. This data may be used for modeling of the thickness of the seasonally thawed layer and ground temperature variation. The knowledge of thermal properties of these samples allows us to view vegetation cover as a separate layer of geological section.

13. A Thousand Topics for Composition: Revised.

ERIC Educational Resources Information Center

Illinois English Bulletin, 1971

1971-01-01

For use by junior and senior high school English teachers and students in search of appropriate subjects for written compositions, this publication contains 1,237 topics compiled from a questionnaire sent to about 250 teachers. The topics are divided into categories: personal reminiscences, personal reactions, the familiar essay, description,…

14. Fostering Topic Knowledge: Essential for Academic Writing

ERIC Educational Resources Information Center

Proske, Antje; Kapp, Felix

2013-01-01

Several researchers emphasize the role of the writer's topic knowledge for writing. In academic writing topic knowledge is often constructed by studying source texts. One possibility to support that essential phase of the writing process is to provide interactive learning questions which facilitate the construction of an adequate situation…

15. Topics in Culture Learning, Volume 4, 1976.

ERIC Educational Resources Information Center

Brislin, Richard W., Ed.

Volume 4 of an annual series, this issue focuses chiefly on a variety of perspectives relating to cross-cultural research. The major article is comprised of 15 topics encompassing cognitive and affective aspects of culture contact, language and communication, and culture exchange. The topics address Japanese perceptions of foreigners, learning of…

16. Some Teaching Topics from Space Science

ERIC Educational Resources Information Center

Balding, G. M.

1972-01-01

Short notes on a variety of science topics provide information derived from space sciences that can be used to add interest and up-to-date data to science lessons. Topics are arranged alphabetically from Alpha particles to X-rays, and include some from each of the physical, earth, and biological sciences. (AL)

17. Anesthesia: A Topic for Interdisciplinary Study.

ERIC Educational Resources Information Center

Labianca, Dominick A.; Reeves, William J.

1977-01-01

Describes an interdisciplinary approach for teaching the topic of anesthesia as one aspect of a chemistry-oriented course for nonscience majors which focuses on timely topics such as the energy crisis and drugs. Historical treatment with the examination of literature is emphasized in teaching. (HM)

18. Common Topics and Commonplaces of Environmental Rhetoric

ERIC Educational Resources Information Center

Ross, Derek G.

2013-01-01

Common topics are words or phrases used to develop argument, and commonplaces aid memory or catalyze frames of understanding. When used in argumentation, each may help interested parties more effectively communicate valuable scientific and environment-related information. This article describes 12 modern topics of environmental rhetoric,…

19. Torpedo: topic periodicity discovery from text data

Wang, Jingjing; Deng, Hongbo; Han, Jiawei

2015-05-01

Although history may not repeat itself, many human activities are inherently periodic, recurring daily, weekly, monthly, yearly or following some other periods. Such recurring activities may not repeat the same set of keywords, but they do share similar topics. Thus it is interesting to mine topic periodicity from text data instead of just looking at the temporal behavior of a single keyword/phrase. Some previous preliminary studies in this direction prespecify a periodic temporal template for each topic. In this paper, we remove this restriction and propose a simple yet effective framework Torpedo to mine periodic/recurrent patterns from text, such as news articles, search query logs, research papers, and web blogs. We first transform text data into topic-specific time series by a time dependent topic modeling module, where each of the time series characterizes the temporal behavior of a topic. Then we use time series techniques to detect periodicity. Hence we both obtain a clear view of how topics distribute over time and enable the automatic discovery of periods that are inherent in each topic. Theoretical and experimental analyses demonstrate the advantage of Torpedo over existing work.

20. Infantile generalized hypertrichosis caused by topical minoxidil.

PubMed

Rampon, Greice; Henkin, Caroline; de Souza, Paulo Ricardo Martins; Almeida, Hiram Larangeira de

2016-01-01

Rare cases of hypertrichosis have been associated with topically applied minoxidil. We present the first reported case in the Brazilian literature of generalized hypertrichosis affecting a 5-year-old child, following use of minoxidil 5%, 20 drops a day, for hair loss. The laboratory investigation excluded hyperandrogenism and thyroid dysfunction. Topical minoxidil should be used with caution in children. PMID:26982785

1. Infantile generalized hypertrichosis caused by topical minoxidil*

PubMed Central

Rampon, Greice; Henkin, Caroline; de Souza, Paulo Ricardo Martins; de Almeida Jr, Hiram Larangeira

2016-01-01

Rare cases of hypertrichosis have been associated with topically applied minoxidil. We present the first reported case in the Brazilian literature of generalized hypertrichosis affecting a 5-year-old child, following use of minoxidil 5%, 20 drops a day, for hair loss. The laboratory investigation excluded hyperandrogenism and thyroid dysfunction. Topical minoxidil should be used with caution in children. PMID:26982785

2. Topic Maps e-Learning Portal Development

ERIC Educational Resources Information Center

Olsevicova, Kamila

2006-01-01

Topic Maps, ISO/IEC 13250 standard, are designed to facilitate the organization and navigation of large collections of information objects by creating meta-level perspectives of their underlying concepts and relationships. The underlying structure of concepts and relations is expressed by domain ontologies. The Topics Maps technology can become…

3. MODIS Snow-Cover Products

NASA Technical Reports Server (NTRS)

Hall, Dorothy K.; Riggs, George A.; Salomonson, Vinvent V.; DiGirolamo, Nicolo; Bayr, Klaus J.; Houser, Paul (Technical Monitor)

2001-01-01

On December 18, 1999, the Terra satellite was launched with a complement of five instruments including the Moderate Resolution Imaging Spectroradiometer (MODIS). Many geophysical products are derived from MODIS data including global snow-cover products. These products have been available through the National Snow and Ice Data Center (NSIDC) Distributed Active Archive Center (DAAC) since September 13, 2000. MODIS snow-cover products represent potential improvement to the currently available operation products mainly because the MODIS products are global and 500-m resolution, and have the capability to separate most snow and clouds. Also the snow-mapping algorithms are automated which means that a consistent data set is generated for long-term climates studies that require snow-cover information. Extensive quality assurance (QA) information is stored with the product. The snow product suite starts with a 500-m resolution swath snow-cover map which is gridded to the Integerized Sinusoidal Grid to produce daily and eight-day composite tile products. The sequence then proceeds to a climate-modeling grid product at 5-km spatial resolution, with both daily and eight-day composite products. A case study from March 6, 2000, involving MODIS data and field and aircraft measurements, is presented. Near-term enhancements include daily snow albedo and fractional snow cover.

4. Topics in Hawaii's History: Resources and Lesson Plans for Secondary School Teachers.

ERIC Educational Resources Information Center

Odo, Franklin, Ed.; Kawamoto, Kevin, Ed.; McGregor, Davianna, Ed.

Twenty-nine teachers participated in a 4-week National Endowment for the Humanities institute which covered topics from pre-contact Hawaiian population estimates to formation of plantation workforces to contemporary sovereignty issues. The lessons the participants developed are divided into nine sections. Section 1, "Geography," contains articles…

5. Source Book on Air Pollution Topics for Grade and High School Teachers.

ERIC Educational Resources Information Center

Brennan, Eileen G., Ed.; McGovern, John J., Ed.

This publication provides background information and activity suggestions on air pollution and related environmental topics. Student projects and experiments which can be adapted at both elementary and secondary levels are also provided. Information is organized in three parts. Part I covers basic facts about air pollutants including the types,…

6. Topics in Finance Part I--Introduction and Stockholder Wealth Maximization

ERIC Educational Resources Information Center

Laux, Judy

2010-01-01

The following article represents the first in a series dedicated to presenting students the opportunity to better understand the key theoretical constructs in the introductory financial management course. The current essay offers an introduction to the series and covers the topics of stockholder wealth maximization and its close cousin, agency…

7. Essay: Accelerators, Beams and Physical Review Special Topics - Accelerators and Beams

Siemann, Robert H.

2008-05-01

Accelerator science and technology have evolved as accelerators became larger and important to a broad range of science. Physical Review Special Topics - Accelerators and Beams was established to serve the accelerator community as a timely, widely circulated, international journal covering the full breadth of accelerators and beams. The history of the journal and the innovations associated with it are reviewed.

8. Using Contemporary Topics and Internet Resources to Stimulate Student-Centred Learning

ERIC Educational Resources Information Center

Lee, Susan E.; Woods, Kyra J.

2010-01-01

In this paper we describe how we fostered learning by modifying an existing course which covered topics relevant to biosciences. This course was offered predominantly to first year undergraduate science, biomedical science and environment students. The students were trained to find reliable scientific information via computer searches, and shown…

9. Academicians' and Practitioners' Views on the Importance of the Topical Content in the First Auditing Course

ERIC Educational Resources Information Center

Armitage, Jack; Poyzer, Jillian K.

2010-01-01

The research question addressed in this study is to compare and identify differences between academics teaching auditing classes and practicing accountants regarding the importance of topics covered in the first university auditing course. This is accomplished by surveying academics and practitioners regarding their perceptions of the importance…

10. Topical steroid addiction in atopic dermatitis

PubMed Central

Fukaya, Mototsugu; Sato, Kenji; Sato, Mitsuko; Kimata, Hajime; Fujisawa, Shigeki; Dozono, Haruhiko; Yoshizawa, Jun; Minaguchi, Satoko

2014-01-01

The American Academy of Dermatology published a new guideline regarding topical therapy in atopic dermatitis in May 2014. Although topical steroid addiction or red burning skin syndrome had been mentioned as possible side effects of topical steroids in a 2006 review article in the Journal of the American Academy of Dermatology, no statement was made regarding this illness in the new guidelines. This suggests that there are still controversies regarding this illness. Here, we describe the clinical features of topical steroid addiction or red burning skin syndrome, based on the treatment of many cases of the illness. Because there have been few articles in the medical literature regarding this illness, the description in this article will be of some benefit to better understand the illness and to spur discussion regarding topical steroid addiction or red burning skin syndrome. PMID:25378953

11. Topical antioxidants in radiodermatitis: a clinical review.

PubMed

Kodiyan, Joyson; Amber, Kyle T

2015-09-01

Radiation-induced skin toxicity is the most prevalent side effect of radiation therapy. Not only does it have a significant effect on patients' quality of life, but it also results in poor follow-up and early termination of radiotherapy treatment. Several skin care practices and topical applications have been studied in the field of radiodermatitis, including skin washing, topical steroids, and mechanical skin barriers. Aside from these methods, many patients turn to complementary and alternative medicine for the prevention and treatment of radiodermatitis. Many of these alternative therapies are topically applied antioxidants. While the rationale behind the use of antioxidants in treating radiodermatitis is strong, clinical studies have been far less consistent. Even in large scale randomised controlled trials, findings have been limited by the inconsistent use of topical vehicles and placebos. In this article, the authors review the role of topical antioxidants to better help the practitioner navigate through different available skin directed antioxidants. PMID:26412275

12. Physics of climate change, taught as a topics a course for undergraduate physics majors

2012-10-01

While anthropogenic (human-caused) climate change is generally accepted in the scientific community, there is considerable skepticism among the general population. Science students are often asked by their peers, family members, and others, whether they ``believe'' climate change is occurring and what should be done about it (if anything). While the pertinent material is covered in undergraduate physics courses, it helps to review the basics in order to develop an educated perspective on this topic that is very volatile (socially and politically). The basic topics are introductory quantum mechanics (discrete energy levels of atomic systems), molecular spectroscopy, blackbody radiation, and appreciation for the scientific method (particularly peer-reviewed research). These topics are usually covered in undergraduate modern physics and thermodynamics courses, but a separate course on climate change (taught in Spring 2012) helped ``put things together'' for both the students and their professor.

13. The National Land Cover Database

USGS Publications Warehouse

Homer, Collin H.; Fry, Joyce A.; Barnes, Christopher A.

2012-01-01

The National Land Cover Database (NLCD) serves as the definitive Landsat-based, 30-meter resolution, land cover database for the Nation. NLCD provides spatial reference and descriptive data for characteristics of the land surface such as thematic class (for example, urban, agriculture, and forest), percent impervious surface, and percent tree canopy cover. NLCD supports a wide variety of Federal, State, local, and nongovernmental applications that seek to assess ecosystem status and health, understand the spatial patterns of biodiversity, predict effects of climate change, and develop land management policy. NLCD products are created by the Multi-Resolution Land Characteristics (MRLC) Consortium, a partnership of Federal agencies led by the U.S. Geological Survey. All NLCD data products are available for download at no charge to the public from the MRLC Web site: http://www.mrlc.gov.

14. MODIS Snow-Cover Products

NASA Technical Reports Server (NTRS)

Hall, Dorothy K.; Riggs, George A.; Salomonson, Vincent V.; DiGirolamo, Nicole E.; Bayr, Klaus J.; Houser, Paul R. (Technical Monitor)

2002-01-01

On December 18, 1999, the Terra satellite was launched with a complement of five instruments including the Moderate Resolution Imaging Spectroradiometer (MODIS). Many geophysical products are derived from MODIS data including global snow-cover products. MODIS snow and ice products have been available through the National Snow and Ice Data Center (NSIDC) Distributed Active Archive Center (DAAC) since September 13, 2000. MODIS snow-cover products represent potential improvement to or enhancement of the currently-available operational products mainly because the MODIS products are global and 500-m resolution, and have the capability to separate most snow and clouds. Also the snow-mapping algorithms are automated which means that a consistent data set may be generated for long-term climate studies that require snow-cover information. Extensive quality assurance (QA) information is stored with the products. The MODIS snow product suite begins with a 500-m resolution, 2330-km swath snow-cover map which is then gridded to an integerized sinusoidal grid to produce daily and 8-day composite tile products. The sequence proceeds to a climate-modeling grid (CMG) product at about 5.6-km spatial resolution, with both daily and 8-day composite products. Each pixel of the CMG contains fraction of snow cover from 40 - 100%. Measured errors of commission in the CMG are low, for example, on the continent of Australia in the spring, they vary from 0.02 - 0.10%. Near-term enhancements include daily snow albedo and fractional snow cover. A case study from March 6, 2000, involving MODIS data and field and aircraft measurements, is presented to show some early validation work.

15. Topic maps for archiving space plant experiments

Brinckmann, Enno; Karoliussen, Irene; Hauan, Tore Martin; Fossum, Knut R.

The increasing amount of data collected during Space flight experiments, especially on the ISS, requires a new approach for data archiving. The "ULISSE" project, funded by the European Commission, combines the knowledge of the User Support Operation Centers (USOCs) of the ISS and their industrial partners to build up a database for the integration and dissemination of Space experiments. For plant experiments in Space, the N-USOC in Trondheim (Norway) is responsible to collect and implement the needs of scientists working in the field of plant biology for this bio-informatics tool. Each experiment can be found in a topic map providing interfaces to other experiments or other topics. Topic maps describe among others the ex-periment environment in orbit or on ground, experimental methods, hardware and software, biological processes, and experimental results. Each of these topics needs to be identified by an unambiguous definition, usually a link to a database like a thesaurus or an ontology. A survey was done to see in which of the common ontology databases suitable definitions of the topic names of the N-USOC Topic Map could be found. Thus, the draft N-USOC Topic Map could be linked almost completely to Web based definitions. This will allow embedding Space plant biology experiments into public data management systems. Credits: European Commission (FP7/2007-2013, grant agreement n218815).

16. Cover times of random searches

Chupeau, Marie; Bénichou, Olivier; Voituriez, Raphaël

2015-10-01

How long must one undertake a random search to visit all sites of a given domain? This time, known as the cover time, is a key observable to quantify the efficiency of exhaustive searches, which require a complete exploration of an area and not only the discovery of a single target. Examples range from immune-system cells chasing pathogens to animals harvesting resources, from robotic exploration for cleaning or demining to the task of improving search algorithms. Despite its broad relevance, the cover time has remained elusive and so far explicit results have been scarce and mostly limited to regular random walks. Here we determine the full distribution of the cover time for a broad range of random search processes, including Lévy strategies, intermittent strategies, persistent random walks and random walks on complex networks, and reveal its universal features. We show that for all these examples the mean cover time can be minimized, and that the corresponding optimal strategies also minimize the mean search time for a single target, unambiguously pointing towards their robustness.

17. ESTIMATING AND PROJECTING IMPERVIOUS COVER

EPA Science Inventory

Effective methods to estimate and project impervious cover can help identify areas where a watershed is at risk of changing rapidly from one with relatively pristine streams to one with streams with significant symptoms of degradation. In collaboration with the USEPA, Region 4, ...

18. COVERING A CORE BY EXTRUSION

DOEpatents

Karnie, A.J.

1963-07-16

A method of covering a cylindrical fuel core with a cladding metal ms described. The metal is forced between dies around the core from both ends in two opposing skirts, and as these meet the ends turn outward into an annular recess in the dics. By cutting off the raised portion formed by the recess, oxide impurities are eliminated. (AEC)

19. Digital Social Network Mining for Topic Discovery

Networked computers are expanding more and more around the world, and digital social networks becoming of great importance for many people's work and leisure. This paper mainly focused on discovering the topic of exchanging information in digital social network. In brief, our method is to use a hierarchical dictionary of related topics and words that mapped to a graph. Then, with comparing the extracted keywords from the context of social network with graph nodes, probability of relation between context and desired topics will be computed. This model can be used in many applications such as advertising, viral marketing and high-risk group detection.

20. Topics in Social Psychology: Further Classroom Demonstrations.

ERIC Educational Resources Information Center

Singleton, Royce, Jr.; Kerber, Kenneth W.

1980-01-01

Presents ideas for stimulating students' interest in college level sociology courses by involving students in individual v group decision making, nonverbal communication, romantic love, and ethnic stereotypes. Tips for organizing classroom demonstrations around these topics are presented. (Author/DB)

1. Treatment of alopecia areata with topical sensitizers.

PubMed

Sutherland, Lesley; Laschinger, Mary; Syed, Zain U; Gaspari, Anthony

2015-01-01

For those with severe alopecia areata, with greater than 50% scalp involvement, topical immunotherapy with diphenylcyclopropenone or squaric acid dibutylester is considered the treatment of choice. This article not only reviews the safety and efficacy of topical sensitizers for the treatment of alopecia areata but also highlights strides that have been made in the literature concerning their use in pediatric populations, molecular mechanisms of efficacy, and improved safety through targeted delivery methods. PMID:25581667

2. Topical and oral therapeutic approach to rosacea.

PubMed

Helfrich, Yolanda R; Maier, Lisa M

2016-06-01

Rosacea is an inflammatory condition of the skin, primarily affecting the central convexities of the face. Various topical and oral therapeutic approaches exist. Most have been developed to treat the papulopustular subtype of rosacea; however, other approaches can be used to treat the erythematotelangiectatic, ocular, and phymatous subtypes. This review provides a summary of available topical and oral approaches for the treatment of rosacea. PMID:27416312

3. Stripline dipole with dielectric covering

Wang, J.; Hansen, V.

The use of stripline antennas has greatly increased during the last ten years. In connection with an employment of the antennas, it is often necessary to provide an additional dielectric covering layer to protect the antenna against atmospheric conditions. Water or ice layers can also be described as dielectric layers. The present investigation is concerned with the effect of such additional layers on the radiation characteristics of stripline dipoles. A description is presented of a procedure for the calculation of all important antenna characteristics, taking into account current distribution, input impedance, radiation characteristics, the excitation of surface waves, and aspects of coupling. With the aid of a number of examples it is shown that even a thin covering layer can have a pronounced effect. Such layers can, therefore, also be employed to modify the antenna radiation characteristics to improve their suitability for a given application.

4. Sky Cover from MFRSR Observations

SciTech Connect

Kassianov, Evgueni I.; Barnard, James C.; Berg, Larry K.; Flynn, Connor J.; Long, Charles N.

2011-07-01

The diffuse all-sky surface irradiances measured at two nearby wavelengths in the visible spectral range and their model clear-sky counterparts are two main components of a new method for estimating the fractional sky cover of different cloud types, including cumulus clouds. The performance of this method is illustrated using 1-min resolution data from ground-based Multi-Filter Rotating Shadowband Radiometer (MFRSR). The MFRSR data are collected at the U.S. Department of Energy Atmospheric Radiation Measurement (ARM) Climate Research Facility (ACRF) Southern Great Plains (SGP) site during the summer of 2007 and represent 13 days with cumulus clouds. Good agreement is obtained between estimated values of the fractional sky cover and those provided by a well-established independent method based on broadband observations.

5. Sky cover from MFRSR observations

Kassianov, E.; Barnard, J. C.; Berg, L. K.; Flynn, C.; Long, C. N.

2011-07-01

The diffuse all-sky surface irradiances measured at two nearby wavelengths in the visible spectral range and their modeled clear-sky counterparts are the main components of a new method for estimating the fractional sky cover of different cloud types, including cumuli. The performance of this method is illustrated using 1-min resolution data from a ground-based Multi-Filter Rotating Shadowband Radiometer (MFRSR). The MFRSR data are collected at the US Department of Energy Atmospheric Radiation Measurement (ARM) Climate Research Facility (ACRF) Southern Great Plains (SGP) site during the summer of 2007 and represent 13 days with cumuli. Good agreement is obtained between estimated values of the fractional sky cover and those provided by a well-established independent method based on broadband observations.

6. Covering Climate Change in Wikipedia

Arritt, R. W.; Connolley, W.; Ramjohn, I.; Schulz, S.; Wickert, A. D.

2010-12-01

The first hit in an internet search for "global warming" using any of the three leading search engines (Google, Bing, or Yahoo) is the article "Global warming" in the online encyclopedia Wikipedia. The article garners about half a million page views per month. In addition to the site's visibility with the public, Wikipedia's articles on climate-related topics are widely referenced by policymakers, media outlets, and academia. Despite the site's strong influence on public understanding of science, few geoscientists actively participate in Wikipedia, with the result that the community that edits these articles is mostly composed of individuals with little or no expertise in the topic at hand. In this presentation we discuss how geoscientists can help shape public understanding of science by contributing to Wikipedia. Although Wikipedia prides itself on being "the encyclopedia that anyone can edit," the site has policies regarding contributions and behavior that can be pitfalls for newcomers. This presentation is intended as a guide for the geoscience community in contributing to information about climate change in this widely-used reference.

7. Covers by polars of arrangements

SciTech Connect

Eaves, B.C. . Systems Optimization Lab.); Hoffman, A.J. )

1990-08-01

For a collection of hyperplanes passing through the origin in euclidean space let S be the induced subdivision. Let T be the collection of polars of the full cells of S. If only the origin lies in all hyperplanes, T forms a {kappa} {approximately} fold cover of euclidean space. If, in addition, the collection of hyperplanes is of size m and is regular, then {kappa} is m {minus} 1 choose n {minus} 1. Other similar results relate to spheres, hemispheres, and linear programming.

8. Covering and Reimbursing Telehealth Services.

PubMed

Blackman, Kate

2016-01-01

Policymakers who are striving to achieve better health care, improved health outcomes and lower costs are considering new strategies and technologies. Telehealth is a tool that uses technology to provide health services remotely, and state leaders are looking to it now more than ever as a way to address workforce gaps and reach underserved patients. Among the challenges facing state lawmakers who are working to introduce or expand telehealth is how to handle covering patients and reimbursing providers. PMID:27032126

9. Techniques Deriving Land Cover and Earth Surface Deformation Information from Polarimetric SAR Interferometry- Final Report

Pottier, E.; Chen, E.; Li, Z.; Hong, W.; Xiang, M.; Li, Y.; Cloude, S. R.; Papathanassiou, K.; Zhang, L.; Li, X.

2013-01-01

In this paper we provide a summary of activities carried out under the DRAGON collaborative program in a project concerned with the application of Pol-InSAR to deriving land cover and Earth Surface deformation information. This project (ID. 5344) is based around four main scientific topics: Land Cover Analysis, Earth Surface Deformation Monitoring and DEM Extraction, Forest Vertical Structure Parameters Extraction and PolSARpro Software Development.

10. Hot topics in the prevention of respiratory syncytial virus disease.

PubMed

Habibi, Maximillian S; Patel, Sanjay; Openshaw, Peter

2011-03-01

The 7th International Respiratory Syncytial Virus Symposium took place in Hotel Blijdorp, Rotterdam, The Netherlands. The series has been running since 1996; this meeting took place after a 3-year gap, and was attended by approximately 200 clinicians, scientists and industry representatives from all over the world. The conference covered all aspects of respiratory syncytial virus disease, including virology, cell biology, pathogenesis, clinical presentation, diagnosis, immunology, vaccines, antivirals and other therapeutic approaches. Reviews by invited keynote speakers were accompanied by oral and poster presentations, with ample opportunity for discussion of unpublished work. This article summarizes a small selection of hot topics from the meeting, focused on pathogenesis, therapeutics and vaccine development. PMID:21434796

11. A Legal Odyssey, 2001. Papers [of the] Education Law Association Conference (47th, Albuquerque, New Mexico, November 15-17, 2001). Topic Outlines.

ERIC Educational Resources Information Center

Education Law Association, Dayton, OH.

This document is a collection of 53 topic outlines and conference papers whose topics cover a multitude of aspects of educational law. Subjects include the impacts of the Individuals with Disabilities Education Act (IDEA) on "normal" students, rights of nontenured teachers, sexual discrimination and harassment, school disciplinary issues,…

12. Topical Drug Delivery for Chronic Rhinosinusitis

PubMed Central

Liang, Jonathan; Lane, Andrew P.

2013-01-01

Chronic rhinosinusitis is a multifactorial disorder that may be heterogeneous in presentation and clinical course. While the introduction of endoscopic sinus surgery revolutionized surgical management and has led to significantly improved patient outcomes, medical therapy remains the foundation of long-term care of chronic rhinosinusitis, particularly in surgically recalcitrant cases. A variety of devices and pharmaceutical agents have been developed to apply topical medical therapy to the sinuses, taking advantage of the access provided by endoscopic surgery. The goal of topical therapy is to address the inflammation, infection, and mucociliary dysfunction that underlies the disease. Major factors that impact success include the patient’s sinus anatomy and the dynamics of the delivery device. Despite a growing number of topical treatment options, the evidence-based literature to support their use is limited. In this article, we comprehensively review current delivery methods and the available topical agents. We also discuss biotechnological advances that promise enhanced delivery in the future, and evolving pharmacotherapeutical compounds that may be added to rhinologist’s armamentarium. A complete understand of topical drug delivery is increasingly essential to the management of chronic rhinosinusitis when traditional forms of medical therapy and surgery have failed. PMID:23525506

13. Topical Antimicrobials for Burn Infections – An Update

PubMed Central

Sevgi, Mert; Toklu, Ani; Vecchio, Daniela; Hamblin, Michael R

2014-01-01

The relentless rise in antibiotic resistance among pathogenic bacteria and fungi, coupled with the high susceptibility of burn wounds to infection, and the difficulty of systemically administered antibiotics to reach damaged tissue, taken together have made the development of novel topical antimicrobials for burn infections a fertile area of innovation for researchers and companies. We previously covered the existing patent literature in this area in 2010, but the notable progress made since then, has highlighted the need for an update to bring the reader up to date on recent developments. New patents in the areas of topically applied antibiotics and agents that can potentiate the action of existing antibiotics may extend their useful lifetime. Developments have also been made in biofilm-disrupting agents. Antimicrobial peptides are nature’s way for many life forms to defend themselves against attack by pathogens. Silver has long been known to be a highly active antimicrobial but new inorganic metal derivatives based on bismuth, copper and gallium have emerged. Halogens such as chlorine and iodine can be delivered by novel technologies. A variety of topically applied antimicrobials include chitosan preparations, usnic acid, ceragenins and XF porphyrins. Natural product derived antimicrobials such as tannins and essential oils have also been studied. Novel techniques to deliver reactive oxygen species and nitric oxide in situ have been developed. Light-mediated techniques include photodynamic therapy, ultraviolet irradiation, blue light, low-level laser therapy and titania photocatalysis. Passive immunotherapy employs antibodies against pathogens and their virulence factors. Finally an interesting new area uses therapeutic microorganisms such as phages, probiotic bacteria and protozoa to combat infections. PMID:24215506

14. 46 CFR 171.117 - Dead covers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Dead covers. 171.117 Section 171.117 Shipping COAST... Dead covers. (a) Except as provided in paragraph (b) of this section, each port light with the sill located below the margin line must have a hinged, inside dead cover. (b) The dead cover on a port...

15. 7 CFR 319.8-10 - Covers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 5 2012-01-01 2012-01-01 false Covers. 319.8-10 Section 319.8-10 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Foreign Cotton and Covers Conditions of Importation and Entry of Cotton and Covers § 319.8-10 Covers....

16. [Topical felbinac in therapy of athletic injuries].

PubMed

Leeb, B

1994-02-28

In the treatment of acute soft tissue injuries, topical nonsteroidal anti-inflammatory drugs are both highly effective and well tolerated. Target is a monopreparation that meets the demands made on a modern topical agent. The active substance, felbinac, readily, penetrates into the tissue affected and accumulates locally, selectively inhibiting inflammation and alleviating pain. This synoptic report on the clinical trials confirm the significant clinical superiority of felbinac over placebo. As compared with piroxicam, felbinac, is more successful in eliminating symptoms. The rapid alleviation of pain by the topical felbinac results in an improvement in the restriction of mobility and rapid restitution of function. The cooling, nongreasy gel base further favors the high level of acceptance of this well-tolerated preparation. PMID:8163257

17. Topical minoxidil: cardiac effects in bald man.

PubMed Central

Leenen, F H; Smith, D L; Unger, W P

1988-01-01

Systemic cardiovascular effects during chronic treatment with topical minoxidil vs placebo were evaluated using a double-blind, randomized design for two parallel groups (n = 20 for minoxidil, n = 15 for placebo). During 6 months of follow-up, blood pressure did not change, whereas minoxidil increased heart rate by 3-5 beats min-1. Compared with placebo, topical minoxidil caused significant increases in LV end-diastolic volume, in cardiac output (by 0.751 min-1) and in LV mass (by 5 g m-2). We conclude that in healthy subjects short-term use of topical minoxidil is likely not to be detrimental. However, safety needs to be established regarding ischaemic symptoms in patients with coronary artery disease as well as for the possible development of LV hypertrophy in healthy subjects during years of therapy. PMID:3191000

18. Topical Nitroglycerine in Perniosis/Chilblains.

PubMed

Verma, Prashant

2015-01-01

The treatment of perniosis is largely inadequate. The success rate of 0.2% nitroglycerine ointment is demonstrated in the present series. Twenty-two patients clinically diagnosed with severe perniosis were prescribed the topical vasodilator nitroglycerine. Digital photography and patient self-report of the clinical appearance, degree of irritation, and pain and soreness of the lesions were assessed on a 3-point scale to assess therapeutic response. A total of 18 of the 22 patients had regression of the lesions within the first week of treatment and complete regression in 2 weeks. Of these patients, 2 who experienced a relapse were successfully treated with another course of topical nitroglycerine. Two of 22 patients had regression of the lesions during the second week and complete regression in another week. Response was delayed in patients with a longer duration of disease. Topical 0.2% nitroglycerine ointment may be a promising alternative treatment option in perniosis. PMID:26380502

19. Effects of Cover Stories on Problem Solving in a Statistics Course

ERIC Educational Resources Information Center

Ricks, Travis Rex; Wiley, Jennifer

2014-01-01

Does having more knowledge or interest in the topics used in example problems facilitate or hinder learning in statistics? Undergraduates enrolled in Introductory Psychology received a lesson on central tendency. Following the lesson, half of the students completed a worksheet with a baseball cover story while the other half received a weather…

20. Systemic and topical drugs for aging skin.

PubMed

Kockaert, Michael; Neumann, Martino

2003-08-01

The rejuvenation of aging skin is a common desire for our patients, and several options are available. Although there are some systemic methods, the most commonly used treatments for rejuvenation of the skin are applied topically. The most frequently used topical drugs include retinoids, alpha hydroxy acids (AHAs), vitamin C, beta hydroxy acids, anti-oxidants, and tocopherol. Combination therapy is frequently used; particularly common is the combination of retinoids and AHAs. Systemic therapies available include oral retinoids and vitamin C. Other available therapies such as chemical peels, face-lifts, collagen, and botulinum toxin injections are not discussed in this article. PMID:12884471

1. Erythema Dyschromicum Perstans: Response to Topical Tacrolimus

PubMed Central

Mahajan, Vikram K; Chauhan, Pushpinder S; Mehta, Karaninder S; Sharma, Anju Lath

2015-01-01

Background: Erythema dyschromicum perstans, a rare dermatosis of obscure etiopathogenesis and significant cosmetic morbidity, have no satisfactory treatment. Observations: Two patients with having characteristic asymptomatic and slowly progressive, slate-grey macular lesions with distinct red borders involving the face, neck, upper trunk and limbs were diagnosed clinicopathologically as erythema dyschromicum perstans. Both were treated successfully with topical tacrolimus 0.1% ointment. Conclusions: Overall, response to several therapeutic modalities including clofazimine and dapsone therapy is said to vary from complete failure to variable or inconsistent. Topical tarolimus provides an effective and safe alternative therapeutic option in erythema dyschromicum perstans. PMID:26538750

2. Vulvar Skin Atrophy Induced by Topical Glucocorticoids

PubMed Central

Johnson, Elisabeth; Groben, Pamela; Eanes, Alisa; Iyer, Priya; Ugoeke, Joseph; Zolnoun, Denniz

2011-01-01

Steroid induced skin atrophy is the most frequent and perhaps most important cutaneous side effect of topical glucocorticoid therapy. To date, it has not been described in vulvar skin. We describe a patient with significant vulvar skin atrophy following prolonged steroid application to treat vulvar dermatitis. The extensive atrophy in the perineum resulted in secondary ‘webbing’ and partial obstruction of genital hiatus and superimposed dyspareunia. Prolonged topical steroids may result in atrophic changes in vulvar skin. Therefore, further research in clinical correlates of steroid-induced atrophy in the vulvar region is warranted. PMID:22594868

3. Safety of Topical Dermatologic Medications in Pregnancy.

PubMed

Patel, Viral M; Schwartz, Robert A; Lambert, W Clark

2016-07-01

Dermatologic drugs should be employed with caution in women of childbearing age who are pregnant or considering pregnancy. Topical drugs have little systemic absorption. Therefore, they are deemed safer than oral or parenteral agents and less likely to harm the fetus. However, their safety profile must be assessed cautiously, as there is limited available data. In this article, we aggregate human and animal studies and provide recommendations on using topical dermatologic medications in pregnancy.

J Drugs Dermatol. 2016;15(7):830-834. PMID:27391632

4. Topical diclofenac therapy for osteoarthritis: a meta-analysis of randomized controlled trials.

PubMed

Deng, Zhen-Han; Zeng, Chao; Yang, Ye; Li, Yu-Sheng; Wei, Jie; Yang, Tuo; Li, Hui; Lei, Guang-Hua

2016-05-01

The objective of this study was to evaluate the efficacy and safety of topical diclofenac therapy for osteoarthritis (OA). A meta-analysis of randomized controlled trials was conducted. A comprehensive literature search, covering the databases of Medline, the Cochrane Central Register of Controlled Trials, and EMBASE, was conducted in September 2014 to identify the randomized controlled trials which adopted the topical diclofenac therapy for OA. A total of nine papers were included in this meta-analysis. Topical diclofenac appears to be effective in both pain relief (standard mean differences (SMD) = 0.40; 95 % confidence interval (CI) 0.19 to 0.62; P = 0.0003) and function improvement (SMD = 0.23; 95 % CI 0.03 to 0.43; P = 0.03) when compared with the control group. The sensitivity analysis and subgroup analysis showed that the result of pain intensity was stable and reliable, while the result of physical function improvement was vague. With respect to safety, topical diclofenac demonstrated a higher incidence of adverse events such as dry skin, rash, dermatitis, neck pain, and withdrawal. Topical diclofenac is effective in pain relief as a treatment of OA. It may also have a potential effect in function improvement, which needs further studies to be explored. Although, some adverse effects were observed in the application of topical diclofenac, none of them was serious. PMID:26242469

5. Conference Report: Bioanalysis-related topics presented at the International Conference and Exhibition on Biowaivers and Biosimilars.

PubMed

Colletti, Kelly S

2013-03-01

This conference of approximately 30 professionals attracted a diverse group of attendees, whose expertise spanned the broad topics of development, production, testing and regulation of biosimilars. The topics covered during this meeting were varied in scope due to the breadth of knowledge of the attendees. Topics of discussion included: biowaivers for small molecules; patent law and interpretation of the Biologics Price Competition and Innovation Act; analytical tools for the characterization of a biosimilar; novel production methods; bioanalytical methods; immunogenicity considerations; formulation techniques; and the characterization of the glycosylation of biosimilars. PMID:23425268

6. Optimizing the use of topical agents in psoriasis.

PubMed

Stein Gold, Linda F

2014-03-01

The vast majority of patients with psoriasis have localized disease that is manageable by topical therapy alone, and patients with more severe disease still require topical treatment for plaques that persist despite effective systemic treatment or phototherapy. Nevertheless, little attention today is paid to topical therapy, including new topical treatments.This article briefly addresses key issues that can adversely affect the use of and compliance with currently available topical treatments, as well as new and emerging topical agents for psoriasis. PMID:24979541

7. Topic Congruence and Topic Interest: How Do They Affect Second Language Reading Comprehension?

ERIC Educational Resources Information Center

Lee, Sang-Ki

2009-01-01

Because human memory is largely reconstructive, people tend to reorganize and reevaluate an event in a way that is coherent to the truth values held in their belief system. This study investigated the role of topic congruence (defined as whether the reading content corresponds with readers' prior beliefs towards a contentious topic) in second…

8. Methods for Cloud Cover Estimation

NASA Technical Reports Server (NTRS)

Glackin, D. L.; Huning, J. R.; Smith, J. H.; Logan, T. L.

1984-01-01

Several methods for cloud cover estimation are described relevant to assessing the performance of a ground-based network of solar observatories. The methods rely on ground and satellite data sources and provide meteorological or climatological information. One means of acquiring long-term observations of solar oscillations is the establishment of a ground-based network of solar observatories. Criteria for station site selection are: gross cloudiness, accurate transparency information, and seeing. Alternative methods for computing this duty cycle are discussed. The cycle, or alternatively a time history of solar visibility from the network, can then be input to a model to determine the effect of duty cycle on derived solar seismology parameters. Cloudiness from space is studied to examine various means by which the duty cycle might be computed. Cloudiness, and to some extent transparency, can potentially be estimated from satellite data.

9. Appalachian basin bibliography. Topical report, March 1994

SciTech Connect

Picciano, L.; Armstrong, T.S.

1994-03-01

More than 120 Gas Research Institute reports on gas exploration and production in the Appalachian Basin are listed. They cover geology and reservoir engineering in three gas producing formations: shales, tight gas sands, and coal seams.

10. Sea Changes. Topics in Marine Earth Science.

ERIC Educational Resources Information Center

Awkerman, Gary L.

This publication is designed for use in standard science curricula to develop oceanologic manifestations of certain science topics. Included are teacher guides, student activities, and demonstrations designed to impart ocean science understanding to high school students. The principal theme of Changes in the Sea is presented in this particular…