Possible GOM Development/PGI-37L: An elongated trough observed in the Gulf of Mexico yesterday appears to be more organized (2a, 4), in terms of a ...

over foodborne illness risk factors. A.4 Administrative Control. Any procedure that limits noise exposure by restricting access to noise areas or by control ...

... Fort Devens Sudbury Training Annex, Middlesex County Massachusetts, Remedical (Data Gap) Investigations of Area of Contamination A4 and ...

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The research vessel Alaminos departed Galveston on February 16, 1971 on an extended geological-geophysical cruise to investigate the structure and sediments of selected areas in the Caribbean. The areas investigated were: Yucatan-Colombian Basin; Magdelen...

Using PCR, we screened 411 ticks from four genera collected in Russia and Kazakhstan for the presence of rickettsiae and ehrlichiae. In Russia, we detected �Rickettsia heilongjiangensis,� Rickettsia sp. strain RpA4, and Ehrlichia muris. In Kazakhstan, we detected Rickettsia sp. strain RpA4 and a rickettsia ...

We report on the cloning and molecular characterization of the rat carrier Slc10a4 and its cellular localization in the CNS by immunohistochemistry. Slc10a4 is the rat counterpart of the human orphan carrier SLC10A4, which was recently reported to be highly expressed in ...

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are silent about A (given axiom (A4) but not (A5)). Areas of uncertainty or ignorance like that concerning will then abstract from this example, and provide a general method for using explanation closure axioms as \\sentries

... Areas and Classification A.2 Sunspot Numbers A.3 Solar Magnetic Fields A.4 Calcium Plages A.6(1) Combined and Special Optical Observations, ...

A4 - DOE BNL/PNL Grumman G-1 Data The Southern Oxidants Study (SOS) conducted a major field research campaign in Nashville/Middle Tennessee area in June and ...

... Mo Mach number P forie S wing area d incidence ... aircular frequency A4 sweep angle ... range at emgll side slip angles these coefficients changA wign ...

...their proper relationship with other DoD functional areas (e.g., budget, personnel, logistics, acquisition, civil engineering, etc.). (6) Execute statutory and regulatory financial reporting requirements and render financial...

heat or magnetic susceptibility) describing phase transitions. Existing thermodynamic analogies [1], [2 as physically corresponding to the ordinary laws of thermodynamics. The classical laws of black hole mechanics relativistic horizon area, A=4, as playing the mathematical role of entropy. The geometric thermodynamics

...A-2. In North San Diego Bay, the America's Cup Harbor Anchorage, the water area enclosed...beginning. (g) Area A-4. In Central San Diego Bay, the Bay Bridge Roadstead Anchorage...beginning. (h) Area A-5. In Central San Diego Bay, the Glorietta Bay...

Evaluation, recommendation, development, and application of a process to treat approximately 1,800 cubic yards of soil/sediment contaminated with organic solvents and with U in Area 3A and 4A by a technical assistance team.

Cytochrome P4503A4 (CYP3A4) is the principal drug-metabolizing enzyme in human liver. Drug-drug interactions (DDIs) caused by induction of CYP3A4 can result in decreased exposure to coadministered drugs, with potential loss of efficacy. Immortalized hepatocytes (Fa2N-4 cells) have been proposed as a tool to ...

Rifampin and carbamazepine have been recommended in the U.S. Food and Drug Administration draft drug interaction guidance as CYP3A4 inducers for clinical drug-drug interaction (DDI) studies. To optimize the dose regimens of these inducers for use in DDI studies, their effect at various doses and dosing durations on the area under the curve (AUC) of multiple probe substrates ...

Peroxisome proliferators (PP), including clofibrate (CF), are non-genotoxic rodent carcinogens, and oxidative DNA damages are suggested as a causative event for carcinogenesis. Gene expression profiles differ between hepatic lesions induced by PP and genotoxic carcinogens. Our previous study revealed that expression of L-bifunctional enzyme (enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase, BE) ...

The holographic bound asserts that the entropy $S$ of a system is bounded from above by a quarter of the area ${\\cal A}$ of a circumscribing surface measured in Planck areas: $S\\leq {\\cal A}/4{\\ell^2_P}$. This bound is widely regarded a desideratum of any fundamental theory. Moreover, it was argued that the ...

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As authorized by section 6201(a)(4) of the Deficit Reduction Act of 2005, the Centers for Medicare & Medicaid Services (CMS) awarded the Louisiana Department of Health and Hospitals, Bureau of Primary Care and Rural Health (the Bureau), a Professional Wor...

Section 6201(a)(4) of the Deficit Reduction Act of 2005 authorizes the Centers for Medicare & Medicaid Services (CMS) to award the Louisiana Department of Health and Hospitals (DHH), Bureau of Primary Care & Rural Health (the Bureau), a Professional Workf...

As authorized by section 6201(a)(4) of the Deficit Reduction Act of 2005, the Centers for Medicare & Medicaid Services (CMS) awarded the Louisiana Department of Health and Hospitals (DHH), Bureau of Primary Care and Rural Health (the Bureau), a Profession...

This volume contains plots of the aircraft position track in the target area. There are also plots of the aircraft altitude above the terrain, normal accelerations, roll angle, pitch angle & slant range from the navigation check points and the targets.

This volume contains plots of the aircraft position track in the target area. There are also plots of the aircraft altitude above the terrain, normal accelerations, roll angle, pitch angle & slant range from the navigation check points and the targets.

This volume contains plots of the aircraft position track in the target area. There are also plots of the aircraft altitude above the terrain, normal accelerations, roll angle, pitch angle & slant range from the navigation check points and the targets.

This book contains the following data for the A-4B type aircraft: plots of the aircraft position track in the target area and of the aircraft elevations above mean sea level, along with the terrain elevation under the aircraft track.

Responsible HLI Hengyu Li Substitute JB J�r�mie Bettex Solar simulator large area Responsible AL Alo Lo oven Responsible FZ Fernando Zicarelli Substitute PBR Priscille B�le Rothen BRE S.070 Replication setup

Attention is given to codes that can calculate the coupled general relativity/hydrodynamics equations in two spatial dimensions plus time. These codes are compared, and areas needing improvement are reviewed critically. The potential uses of numerical relativity are examined, and it is noted that in some cases the gravitational field can be chosen to be an analytically known ...

It is proposed to adopt a program incorporating (a) 4.4-mile concrete-lined rectangular flood control channel in Simi Valley, together with 106 acres of park and trail development, including hiking and riding trails, picnic and play area, a continuous lin...

Discussed is a program incorporating (a) 4.4-mile concrete-lined rectangular flood control channel in Simi Valley, together with 128 acres of park and trail development, including hiking and riding trails, picnic and play areas, a continuous linear park e...

Microdosing studies are effective in enabling the early identification of the pharmacokinetic properties of compounds administered to humans. However, the nonlinearity of the pharmacokinetics between microdose and therapeutic dose, attributable to the saturation of metabolic enzymes and transporters, is a major concern. Verapamil and quinidine are good substrates of both the multidrug resistance 1 ...

SummaryEph receptors are widely expressed during cerebral cortical development, yet a role for Eph signaling in the generation of cells during corticogenesis has not been shown. Cortical progenitor cells selectively express one receptor, EphA4, and reducing EphA4 signaling in cultured progenitors suppressed ...

...initiating investigations of places of employment. 85a.4 Section 85a.4...HEALTH INVESTIGATIONS OF PLACES OF EMPLOYMENT § 85a.4 Procedures for initiating investigations of places of employment. (a) Except as...

...2009-04-01 false Procedure for requesting approval. 3a.4 Section 3a.4 Foreign Relations DEPARTMENT OF STATE GENERAL...FOREIGN GOVERNMENTS BY MEMBERS OF THE UNIFORMED SERVICES § 3a.4 Procedure for requesting approval....

... 2011-01-01 2011-01-01 false Investigator. 269a.4 Section 269a.4 Banks and...RESERVE SYSTEM DEFINITIONS § 269a.4 Investigator. The term investigator means the officer designated by the...

We investigate whether imagery of voluntary movements of different body parts activates somatotopical sections of the human motor cortices. We used functional magnetic resonance imaging to detect the cortical activity when 7 healthy subjects imagine performing repetitive (0.5-Hz) flexion/extension movements of the right fingers or right toes, or horizontal movements of the tongue. We also ...

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WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT �?Available data suggest that fesoterodine dosage should not exceed 4?mg once daily when taken concomitantly with potent CYP3A4 inhibitors, such as ketoconazole. Currently, no information is available on whether dose adjustment is necessary when fesoterodine is administered with a moderate ...

We have previously shown that motor areas are engaged when subjects experience illusory limb movements elicited by tendon vibration. However, traditionally cytoarchitectonic area 2 is held responsible for kinesthesia. Here we use functional magnetic resonance imaging and cytoarchitectural mapping to examine whether area 2 is engaged in ...

commercial fishing for halibut in Areas 2A, 2B, 2C, 3A, 3B, 4A, 4B, 4C, VerDate Aug2005 17:51 Mar 06 1�25 A 26�30 B 31�35 C 36�40 D 41�45 E 46�50 F 51�55 G 56+ H (7) Fishing period limits in Area 2A Sharing Plan (CSP) for Area 2A (waters off the U.S. West Coast) and implementing ...

AIM: To identify new markers of hepatocellular carcinoma (HCC) using a proteomic analysis.METHODS: Patients with liver cirrhosis of the three most frequent etiologies: hepatitis C virus, hepatitis B virus and alcoholic liver disease, were included in the study. The samples were analysed by 2D-electrophoresis in order to determine the differential protein expression. The proteins were separated ...

Extracts from sea urchin intestine were screened for new anti-tumour drugs. Four glycolipids, 3'-sulphonoquinovosyl-1', 2'-diacylglyceride (A-4), 3'-sulphonoquinovosyl-1'-monoacylglyceride (2'-lyso A-4, A-5), NeuGc(alpha)2-6Glc(beta)1-1ceramide (A-6) and HSO3-8NeuGc(alpha)2-6Glc(beta)1-1ceramide (A-7), were ...

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and the standard deviation of the random variable x. (c) Find P(x 2 or x > 4). 3. Find the z-scores that has (a.4% of the distribution's area between -z and z. a) -1.645 and 1.645 b) -1.28 and 1.28 c) -1.96 and 1.96 d) -2 and 2 e) -2. A pediatrician measured the heights of 35 randomly selected 6-year old girls and constructed a 90% ...

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... Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Appendix A(4) to Part 61 A(4) Appendix A(4) to Part 61 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY,...

...5 2011-04-01 2011-04-01 false Nondiscrimination requirements of section 401(a)(4). 1.401(a)(4)-1 Section 1.401(a)(4)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY...

...Internal Revenue 11 2011-04-01 2011-04-01 false Agreement pursuant to section 1313(a)(4) as a determination. 1.1313(a)-4 Section 1.1313(a)-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF...

A study was made of the cytoarchitecture of the lateral and medial frontal cortex in the hamadryas baboon (Papio hamadryas). The frontal cortico-cortical connections of areas 46, 8, 6, and 4 were investigated by injection of wheat-germ agglutinine conjugated to horseradish peroxiase (WGA-HRP) into different regions of areas 46, 8, and 6. The lateral region ...

Purpose: To evaluate the effect of the vascular targeting agent, combretastatin A4 phosphate, on tumor oxygenation compared with vascular perfusion/permeability. Methods and Materials: {sup 19}F MRI oximetry and dynamic contrast-enhanced (DCE)-MRI were used to monitor tumor oxygenation and perfusion/permeability in syngeneic 13762NF rat breast carcinoma. ...

The important roles played by glycoconjugates in the recognition of gametes and in fertilization are well documented. In the present study, the nature and distribution of carbohydrate residues of the plasma membrane of spermatozoa of Drosophila melanogaster were characterized by use of FITC-conjugated lectins as probes. The plasma membrane bound agglutinins from Concanavalia ensiformis (Con A) and ...

The holographic bound, S?A/4?P2, asserts that the entropy S of a system is bounded from above by a quarter of the area A of a circumscribing surface measured in Planck areas. This bound is widely regarded as part of the elusive fundamental theory of nature. In fact, the bound is known to be valid for generic weakly ...

Navy damage control personnel (especially firefighters) are often required to work in areas of possible or actual oxygen deficiency and areas where the concentration of smoke or other toxic gases is high. In these situations, the investigator or firefighter normally wears an Oxygen Breathing Apparatus (OBA) for respiratory protection. Presently, the Naval ...

The coupling of a Nambu-Goto string to gravity allows for Schwarzschild black holes whose entropy to area relation is S = (A=4)(1 \\Gamma 4�), where � is the string tension. It is well known that to compute thermal correlation functions and partition functions in field theory in flat Minkowski spacetime one can use path integrals ...

Clearance of atorvastatin occurs through hepatic uptake by organic anion transporting polypeptides (OATPs) and subsequent metabolism by cytochrome P450 (CYP) 3A4. To demonstrate the relative importance of OATPs and CYP3A4 in the hepatic elimination of atorvastatin in vivo, a clinical cassette microdose study was performed. A cocktail consisting of a ...

Purpose: In vitro and in vivo studies indicate that docetaxel is primarily eliminated by hepatic cytochrome P450 (CYP) 3A4-mediated metabolism. Concomitant intake of grapefruit juice (GFJ), a potent intestinal and hepatic CYP 3A4 inhibitor, could have implications on the pharmacokinetics of docetaxel in cancer ...

Purpose: To examine the pathophysiologic impact of treatment with combretastatin A4 phosphate (CA4P) in regions of tumors that ultimately either necrose or survive treatment with this agent. Methods and Materials: Proliferation, perfusion, vessel density, and expression of vascular endothelial growth factor (VEGF) were analyzed in the KHT tumor model after ...

Mar 1, 2011 ... Hacking, C. A. (4) [x] : Vanderveen, A. A. (4) [x] : Striepe, Scott A. (4) [x] : Sagan, C. (3) [x] : Pritchard, E. B. (3) [x] ...

... NADC-77287-60 I' A-4F BLUE ANGEL FLIGHT USAGE DATA - 1976 ... "'LE (FRE A-4F Blue Angel Flight Usage Data 197 Final "p~t, 6 UTH ...

...Section 18a.4 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) DELEGATION OF RESPONSIBILITY IN CONNECTION WITH TITLE VI, CIVIL RIGHTS ACT OF 1964 § 18a.4 Duties of the Director, Contract...

...Section 18a.4 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) DELEGATION OF RESPONSIBILITY IN CONNECTION WITH TITLE VI, CIVIL RIGHTS ACT OF 1964 § 18a.4 Duties of the Director, Contract...

Groundwater yield estimates for geologic formations in consolidated rock areas would be of great value to communities which are interested in development density recommendations for those areas without public water and sewer. One method of estimating groundwater yield is to separate the hydrograph into stormflow and baseflow, and then assume the latter ...

... Catalan, Chinese, Chinese-Traditional, Croatian, Czech, Danish, # Dutch, Finnish, ..... Possible values are: a4, a4wide, letter, legal and # executive. ...

... Accession Number : ADA338342. Title : Commissioning (Phases 4, 4A, 4B). Descriptive Note : Final technical rept. Corporate ...

Oct 12, 2005 ... The experiment consisted of a collection of collimated sodium iodide scintillators, two of which the Low Energy detectors (LED, LED-3 and ...

BackgroundEvery year, 30,000 babies are born with congenital hearing impairment in China. The molecular etiology of hearing impairment in the Chinese population has not been investigated thoroughly. To provide appropriate genetic testing and counseling to families, we performed a comprehensive investigation of the molecular etiology of nonsyndromic deafness in two typical ...

The adhesive area is important to modulate cell behaviors on a substrate. This paper aims to semi-quantitatively examine the existence of the characteristic areas of cell adhesion on the level of individual cells. We prepared a series of micropatterned surfaces with adhesive microislands of various sizes on an adhesion-resistant background, and cultured ...

BACKGROUND: Docetaxel is the mainline treatment approved by the FDA for castration-resistant prostate cancer (CRPC) yet its administration only increases median survival by 2-4 months. Docetaxel is metabolized in the liver by hepatic CYP3A4 activity. Piperine, a major plant alkaloid/amide, has been shown to inhibit the CYP3A4 enzymatic activity in a ...

The EphA4 receptor and its ephrin ligands are involved in astrocytic gliosis following CNS injury. Therefore, a strategy aimed at the blockade of EphA4 signaling could have broad therapeutic interest in brain disorders. We have identified novel small molecule inhibitors of EphA4 kinase in specific enzymatic and cell-based assays. In addition, we have demonstrated in two in vitro models of scratch ...

Background:The vascular disrupting agent combretastatin A4 phosphate (CA4P) causes major regression of animal tumours when given as combination therapy.Methods:Patients with advanced cancer refractory to standard therapy were treated with CA4P as a 10-min infusion, 20?h before carboplatin, paclitaxel, or paclitaxel, followed by ...

.......................................................................................... A-4 A.2 Actinium (235 U) Decay Series