Saliva samples are useful for noninvasive diagnosis of oral and systemic diseases. The water channel protein aquaporin-5 (AQP5) is released into human saliva. Salivary AQP5 levels show a diurnal variation with the secretion of high levels during the waking hours. An age-related decrease in salivary AQP5 levels parallels a decrease in ...
PubMed
... RHYTHMS, USSR, DISEASES, METABOLISM ... NERVOUS SYSTEM, ELECTROCARDIOGRAPHY ... SALIVARY GLANDS, DIGESTIVE SYSTEM. ...
DTIC Science & Technology
Rabbit and goat antisera to human parotid saliva were examined for the presence of antibodies to human salivary histidine-rich polypeptides (HRP). Antibodies to HRP were present in goat serum but were not detectable in serum from rabbits. (Author)
National Technical Information Service (NTIS)
Page 1. AD-A253 532 ~D-A253 532 DEPARTMENT OF THE NAVY(7 OFFICE OF THE CHIEF OF NAVAL OPERATIONS WASHINGTON. ...
... Salivary amylase, a troublesome factor in the starch-gel electrophoresis of saliva proteins, does not attack acrylamide gel. ...
... for the decrease in gland function found during the summer months. (Author). Descriptors : *SALIVARY GLANDS, SECRETION, PERIODIC ...
... gland in children is an alimentary gland; with an ... Descriptors : (*SALIVA, ANALYSIS), (*SALIVARY GLANDS, CHILDRENS), HUMANS, CHILDREN ...
... as possible, the unstimulated secretion of the parotid gland. ... Descriptors : (*SALIVA, SECRETION), SALIVARY GLANDS, COLLECTING METHODS ...
An irreversible loss of salivary gland function often occurs in humans after removal of salivary tumors, after therapeutic radiation of head and neck tumors, as a result of Sj�gren's syndrome and in genetic syndromes affecting gland development. The permanent loss of gland function impairs the oral health of these patients and ...
The formation of salivary glands entails the proliferation of epithelial cells from the stomatodeum into the underlying ectomesenchyme, culminating in a complex network of ducts and acinar bulbs. The extent to which mucins regulate this process is unknown, but they appear to mediate luminal space formation and maturation. Our aim was to examine mucin expression patterns during ...
In order to assess the physiological significance of human salivary BDNF, we have optimized a sensitive and specific enzyme-linked immunosorbent assay (ELISA). We determined the range of salivary BDNF concentrations, the impact of saliva collection method, and the association of salivary BDNF with several ...
PubMed Central
... TSAACO]2.0.CO;2 The Salivary Adenosine/AMP Content of Phlebotomus argentipes Annandale and Brunetti, the ... MSC 0425, Bethesda...
NBII National Biological Information Infrastructure
Platelet activating factor (PAF), a potent phospholipid inflammatory mediator is found in normal human saliva. This study sought to evaluate possible relationships between salivary PAF levels and periodontal disease. One ml of mixed saliva was collected f...
The distribution of rabies virus antigen (RVAg) in human tongue and salivary glands from three cases was studied with ABC immunohistochemical method. Of the 5 tissue blocks from 2 tongues, large amounts of RVAg were found in 4 tissue blocks, located in the serous glands, terminal nerves, some striated muscle fibers and some covering epithelium including ...
Saliva secreted by right and left parotid glands was collected using Leshley-Krasnogosky's capsules. Salivary secretion and aminolytic activity were found to be higher on the chewing side than on the contralateral. Bilateral differences in salivary gland secretion of alkaline and acid phosphatases and pepsinogen were less expressed. ...
Secretory immunoglobulin A is the predominant immunoglobulin in labial minor salivary gland secretions. Its mean concentration is four times higher in these secretions than in parotid gland secretion. The minor salivary glands can produce 30 to 35 percent of the immunoglobulin A that enters the oral cavity. This, together with the potential accessibility ...
Salivary DNA is encountered in many crimes, such as sexual assaults and murders. In this study, saliva from three male donors was deposited on the skin of three female recipients. The amount of male salivary DNA remaining on the female skin was measured over a 96-h period using the Quantifiler� Y Human Male DNA Quantification Kit. In ...
In order to increase current knowledge regarding statherin secretion into the oral cavity, ultrastructural localization of this peptide was investigated in human salivary glands by using a post-embedding immunogold staining technique. Statherin reactivity was found inside the granules of serous cells of parotid and submandibular glands. In parotid granules ...
ObjectivesTumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a multifunctional cytokine that has pro-apoptotic, pro-angiogenic and pro-inflammatory effects. In liver, TWEAK leads to proliferation of progenitor oval cells, but not of mature hepatocytes. This study evaluated the hypothesis that TWEAK overexpression in salivary glands would lead to the proliferation ...
BackgroundThe digestion of dietary starch in humans is initiated by salivary ?-amylase, an endo-enzyme that hydrolyzes starch into maltose, maltotriose and larger oligosaccharides. Salivary amylase accounts for 40 to 50% of protein in human saliva and rapidly alters the physical properties of starch. Importantly, ...
... high number of infected reservoir as well as human cases, may be associated ... of the environment on vectorial capacity of disease vectors. P. papatasi ... ...
... from right and left parotid salivary glands in human ... functional states of both glands were equal ... unstimulated, but more active, gland was generally ...
The salivary proteome is a complex protein mixture resulting from the activity of salivary glands with the contribution of other components that form the oral environment such as oral tissues and micro-organisms. For diagnosis purposes, saliva collection has the great advantage of being an easy and non-invasive technique. Human saliva ...
SummaryThe salivary proteome is a complex protein mixture resulting from the activity of salivary glands with the contribution of other components that form the oral environment such as oral tissues and micro-organisms. For diagnosis purposes, saliva collection has the great advantage of being an easy and non-invasive technique. Human ...
Monitoring of cytomegalovirus markers was carried out in the blood of humans and in the blood, lavage fluid specimens from the throat, and salivary gland tissues of monkeys of different species. Correlation between the percentage of cytomegalovirus infection and age was detected in humans. The virus was most often detected in ...
Tight junctions (TJs) are an essential structure of fluid-secreting cells, such as those in salivary glands. Three major families of integral membrane proteins have been identified as components of the TJ: claudins, occludin, and junctional adhesion molecules (JAMs), plus the cytosolic protein zonula occludens (ZO). We have been working to develop an orally implantable ...
To clarify the production of human epidermal growth factor (EGF) by different salivary glands, the authors measured its concentration by radioimmunoassay separately in whole saliva, in parotid gland (PG) saliva and in mixed submandibular (SMG) and sublingual gland (SLG) saliva. Also, they studied the presence of EGF in PG and SMG by immunohistochemistry. ...
Energy Citations Database
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Dengue virus (DENV), the etiological agent of dengue fever, is transmitted to the human host during blood uptake by an infective mosquito. Infection of vector salivary glands and further injection of infectious saliva into the ...
E-print Network
Usually no distinction is made between female and male salivary glands although cyclic changes of and ? or differences in serum and salivary sex steroid concentrations characterize women and men. Moreover, sexual dimorphism is well recognized in salivary glands of rodents.Salivary glands contain estrogen and ...
The involvement of reactive oxygen species (ROS) in the pathophysiology of Sj�gren�s syndrome (SS), an autoimmune disorder, and irradiation-induced impairments in salivary secretion has been reported. Meanwhile, the strong antioxidant astaxanthin (Ast) has been suggested to have therapeutic effects on various diseases. In the present study, we examined the ROS scavenging ...
Anopheles gambiae is the primary vector of human malaria in sub-Saharan Africa. Invasion of Anopheles salivary glands by Plasmodium sporozoites is a necessary step in the transmission of malaria and is likely to be mediated by specific receptor�ligand interactions. We are interested in identifying putative an A. gambiae salivary ...
P-30 Protein is a novel protein, of molecular weight approximately 15 KD, obtained from the extract of a vertebrate tissue showing in vivo antitumour activity. Cytostatic and cytotoxic effects of this product in its purified form (P-30 Protein) or in partially purified extracts (Pannon) were studied in vitro on human leukaemic HL-60, human submaxillary ...
Treatment of a human salivary epithelial cell line, HSG- PA, with the calmodulin antagonist N-(6-aminohexyl) -5-chloro-1-naphthalen esulfonamideincreased RB (K+) influx and efflux in a manner similar to that resulting from muscarinic (carbachol; Cch) or c...
This article descibes an ethical experimental module of human biological parameters. The enzyme immunoassay (EIA) kit measures human salivary cortisol levels, which can rise due to circadian and environmental changes. This easy to use sampling kit is described as an ideal procedure for students in behavioral neurobiology or ...
NSDL National Science Digital Library
was closely linked to the immunogenicity of specific proteins observed only in G. mor- sitans morsitans saliva species (Figure 1) showed higher immunogenic characteristics only in G. morsitans mor- sitans. In addition- sitans morsitans salivary gland is currently being carried out and should confirm the effectiveness
Reduction in total salivary gland protein from four anopheline vectors of human malaria, Anopheles stephensi Liston, An. albimanus Wiedmann, An. gambiae Giles, and An. freeborni Aitken, was quantified after mosquitoes blood-fed to repletion on human volun...
Heat shock protein 72 (Hsp72) has been detected within saliva, and its presence may contribute to oral defence. It is currently unknown how physiological stress affects salivary Hsp72 or if salivary Hsp72 concentrations reflect plasma Hsp72 concentrations. We studied the effect of exercise upon salivary Hsp72 expression, and using ...
The susceptibility of human salivary proteins to degradation by Candida albicans was studied. The organism was cultivated in either whole-salivary supernatant or parotid fluid, both of which were supplemented with glucose (0.1%). The culture pH's were at, or above, neutrality. After growth, the culture supernatant solutions were ...
Salivary duct carcinoma (SDC) is a rare subtype of salivary gland carcinoma and is considered to be a high-grade aggressive tumor with morphological resemblance to ductal carcinoma of the breast. We present a case of a patient who suffered from metastatic SDC that was positive for human epidermal growth factor receptor-2 (HER-2) and ...
Propagation of ultrashort pulses of intense, infrared light through transparent medium gives rise to a visually spectacular phenomenon known as supercontinuum (white light) generation wherein the spectrum of transmitted light is very considerably broader than that of the incident light. We have studied the propagation of ultrafast (<45 fs) pulses of intense infrared light through biological ...
NASA Astrophysics Data System (ADS)
This report presents results of a study to determine the removal efficiencies of three common home-use pesticides from the skin with human saliva and artificial saliva substitutes. Three popular residential pesticides (chlorpyrifos, pyrethrin I, and piper...
Changes in parotide salivary function, as determined by flow rate and protein secretion, were measured in 31 cancer patients given radiotherapy to the head and neck. After the first week of treatment, a 50% decrease in salivary flow rate and a 60% decrease in protein secretion rate were observed. Salivary function remained at or below ...
Although very attractive for noninvasive specimen collection, saliva has not yet been considered a relevant bodily fluid for the diagnosis and prognosis of diseases. The functional roles of specific salivary peptides and proteins have also not yet been studied in detail. Recent proteomic analysis of human whole saliva has shown that ...
The reaction of 3-methoxyphenylacetic acid, 4-methoxyphenylacetic acid, mesitylthioacetic acid, 2,5-dimethyl-3-furoic acid and 1,4-benzodioxane-6-carboxylic acid with trimethylgallium (1:1) yielded the dimeric complexes [Me(2)Ga(micro-O(2)CCH(2)C(6)H(4)-3-OMe)](2) (1), [Me(2)Ga(micro-O(2)CCH(2)C(6)H(4)-4-OMe)](2) (2), [Me(2)Ga(micro-O(2)CCH(2)SMes)](2) (3) (Mes=2,4,6-Me(3)C(6)H(2)), ...
Apyrases are enzymes that hydrolyze nucleotide di- and triphosphates to orthophosphate and mononucleotides. At least two families of enzymes, belonging to the 5'-nucleotidase and to the actin/heat shock 70/sugar kinase superfamily, have evolved independently to serve the apyrase reaction. Both families require either Ca(2+) or Mg(2+) for their action. A novel apyrase enzyme sequence, with no ...
The role of salivary cortisol and DHEA-S in response to sexual, humorous, and anxiety xxxx Keywords: Cortisol Dehydroepiandrosterone-sulfate Human sexuality Stress Anxiety Arousal Humor Stress and anxiety are commonly thought to be detrimental to sexual function. Several studies in both
We report for the first time a masticatory-lubrication assay system to assess the lubricating properties of salivary constituents. The lubricating ability of the proline-rich glycoprotein (PRG) of parotid saliva was enhanced by human serum albumin. The interactive effect of albumin was abolished by chemically deglycosylating the glycoprotein. Fluorescence ...
-specific expression of a human salivary amylase gene. Genes Dev 1992, 6:1457-1465. 4. Cachon-Gonzalez MB, Fenner SMany human endogenous retrovirus K (HERV-K) proviruses are unique to humans Madalina Barbulescu. Human endogenous retrovirus K (HERV-K) is related to the mouse mammary tumor virus ...
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Page 1. AD-A253 006 " .' I' ; il I "~q I ( ].�. Proceedings PS.YC"HOL,:OGyk in the DEPARTMENT OF DEFENSE DTIC MAY12 1992 ...
Page 1. AD-A253 0000 t/ PROCEEDINGS 3rd International Symposium on Integrated Ferroelectrics Ap; ~ i9 9.-13566 Colorado Springs ...
Page 1. AD-A253 576 Ik 111R111111,1l1 ON WATSON's ANOVA FOR DIRECTIONS BY ... Page 2. ON WATSON'S ANOVA FOR DIRECTIONS BY ...
Page 1. AD-A253 419 ELETCE W WCpJULJ. 6 1992 WdmWRmesa NATIONAL ECONOMIC DEVELOPMENT PROCEDURES MANUAL ...
Page 1. AD-A253 967 __lflllllllE'Illllllilll MECHANISMS AND MODELLING OF ENVIRONMENT-DEPENDENT FATIGUE CRACK ...
Page 1. AD-A253 002 US Army Corps of Engineers Water Resources Support Center Management of Bottom Sediments ...
Page 1. AD-A253 359 INTEGRATED VISION SYSTEM FOR A TARGET SEEKER A FINAL REPORT Submitted to the DTIC Armament Directorate ...
Page 1. AD-A253 331 Semiannual Report Growth, Nitrogen Vacancy Reduction and Solid Solution Formation in Cubic ...
Page 1. AD-A253 108 -. ý ý AGARD-CP-512 C- <� ADVISORY GROUP FOR AEROSPACE RESEARCH & DEVELOPMENT ...
... Procedures such as litigation, administrative hearings and binding arbitration, rely on third party decision makers to break deadlocks and render a ...
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... AD-A253 677 ACCIDENTAL OIL SPILI"4-N,-- ... I and the remaining oil levels in the tank were measured and oil loss was calculated. ...
Thymosin beta 10 (T?10) is a member of beta-thymosins (T?s), a family of low molecular mass peptides abundant in many cell types. In previous studies, T?s have been shown to play essential roles in many cellular functions, including cytokinesis, migration and endocytosis. Recently, T?10 has been found in high quantities in the saliva of human newborns, while it disappeared in ...
Human salivary mucin, a primary mucous membrane coating glycoprotein forms the first line of defense against adverse environments, attributed to the complex formation between mucin subunits and non mucin species. Aim of the study was to emphasize the effect of pH, denaturants (guanidinum hydrochloride, urea) and detergents (CHAPS, TRITON X -100, SDS on ...
The human cytomegalovirus (CMV) proteins US28 and UL33 are homologous to chemokine receptors (CKRs). Knockout of the mouse CMV M33 protein (UL33 homologue) results in substantial attenuation of salivary gland infection/replication and reduced efficiency of reactivation from tissue explants. M33-mediated G protein-coupled signaling is critical for the ...
Opisthorchis viverrini (O. viverrini; known as human liver fluke) is a major health problem in the northeastern region of Thailand. Infection with O. viverrini is the cause of hepatobiliary disease and cholangiocarcinoma (CCA). Previous studies demonstrated specific antibodies to crude O. viverrini antigens in serum from O. viverrini-infected patients. However, no studies have ...
The adsorption of proteins from human whole saliva (HWS) onto silica and hydroxyapatite surfaces (HA) was followed by quartz crystal microbalance with dissipation (QCM-D) and ellipsometry. The influence of different surface properties and adsorption media (water and PBS) on the adsorption from saliva was studied. The viscoelastic properties of the salivary ...
Vanilloid receptor-1 (VR1) was originally found in the nervous system. Recent evidence indicates that VR1 is also expressed in various cell types. We hypothesized that VR1 exists in the human submandibular gland (SMG) and is involved in regulating salivary secretion. VR1 mRNA and protein were expressed in human SMGs and a ...
The proteome of human salivary fluid has the potential to open new doors for disease biomarker discovery. A recent study to comprehensively identify and catalog the human ductal salivary proteome led to the compilation of 1166 proteins. The protein complexity of both saliva and plasma is large, suggesting that a ...
A 190-kDa surface protein antigen (PAc) of Streptococcus mutans binds to human salivary components. For detection of specific binding of the PAc protein to human salivary components, a simple sandwich assay was used. Microtiter plates precoated with recombinant PAc (rPAc), PAc fragments, or S. mutans whole cells ...
Sj�gren's syndrome (SS) is an autoimmune disease affecting exocrine glands, especially the salivary and lacrimal glands. Although most of the SS patients' sera have autoantibodies that can target a variety of antigens, it is not clear what determines which proteins will become autoantigens. The muscarinic receptor M3, an integral plasma membrane protein, has been proposed as ...
This report summarizes studies on 55 immune deficient subjects (including selective IgA deficiency, Agammaglobulinemia, Variable immunodeficiency and Hypergammaglobulinemia). An equal number of sex- and age-matched controls were compared for oral disease ...
Mathematical representations of humans one year, five years, and twenty years (adult) of age have been modified and are discussed in detail in the following sections. These modifications include the addition of a mandible and salivary glands in the head s...
... organs have been extensively studied for use in xenotransplantation to humans because they have similar sizes and ... endogenous retroviruses (Takeuchi et al., 2005). To achieve xenotransplantation from p...
Task, Immune dysregulation and clinical risk: >6 month mission duration ... 3D Tissue Analogs for the Study of Varicella-Zoster Virulence and Infectivity ... Validating The Use Of Salivary Samples For Pharmacokinetic Measures Of Sleep ...
NASA Website
Validating The Use Of Salivary Samples For Pharmacokinetic Measures Of Sleep Medications, ... Samples are being collected from the subjects in their ongoing study, ... Gap, PH2: What drug interactions may adversely affect clinical care? ...
Lactoferrin (Lf), an iron-binding salivary glycoprotein, plays an important role in human innate defense against local mucosal infection. We hypothesized that Lf interferes with initial oral bacterial attachment to surfaces by iron sequestration, so inhib...
Past studies have indicated that human whole saliva contains several amylolytic components. The possible existence of such components in parotid saliva was investigated. Crystalline amylase was isolated from parotid saliva and was found by several criteri...
Detection of human parotid salivary proteins by dansylation and UV-transillumination after sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) has been compared with Coomassie Blue R-250 and silver staining procedures. Dansylation gives superior results in terms of both resolution and sensitivity, especially with basic proline-rich ...
Monitoring concentrations of stress hormones is an important tool for behavioral research and conservation for animals both in the wild and captivity. Glucocorticoids can be measured in mammals as an indicator of stress by analyzing blood, feces, urine, hair, feathers, or saliva. The advantages of using saliva for measuring cortisol concentrations are three-fold: it is minimally invasive, multiple ...
The value of serial salivary progesterone (P) determinations for evaluation of corpus luteum function compared with sporadic serum samplings is recognized. Salivary P concentrations have previously been determined by a relatively difficult assay which utilizes a tritiated radioligand. The present study was designed to compare this conventional method with ...
