Sandi, Giselle; Ingram, Diana; Welch, Mary Jane; Ocampo, Edith V
2015-01-01
Background Hispanic adults in the United States are at particular risk for diabetes and inadequate blood pressure control. Physical activity improves these health problems; however Hispanic adults also have a low rate of recommended aerobic physical activity. To address improving physical inactivity, one area of rapidly growing technology that can be utilized is text messaging (short message service, SMS). A physical activity research team, Text4Walking, had previously developed an initial database of motivational physical activity text messages in English that could be used for physical activity text messaging interventions. However, the team needed to translate these existing English physical activity text messages into Spanish in order to have culturally meaningful and useful text messages for those adults within the Hispanic population who would prefer to receive text messages in Spanish. Objective The aim of this study was to translate a database of English motivational physical activity messages into Spanish and review these text messages with a group of Spanish speaking adults to inform the use of these text messages in an intervention study. Methods The consent form and study documents, including the existing English physical activity text messages, were translated from English into Spanish, and received translation certification as well as Institutional Review Board approval. The translated text messages were placed into PowerPoint, accompanied by a set of culturally appropriate photos depicting barriers to walking, as well as walking scenarios. At the focus group, eligibility criteria for this study included being an adult between 30 to 65 years old who spoke Spanish as their primary language. After a general group introduction, participants were placed into smaller groups of two or three. Each small group was asked to review a segment of the translated text messages for accuracy and meaningfulness. After the break out, the group was brought back together
Mukherjee, Partha; Leroy, Gondy; Kauchak, David; Navarrete, Brianda Armenta; Diaz, Damian Y.; Colina, Sonia
2017-01-01
Simplifying medical texts facilitates readability and comprehension. While most simplification work focuses on English, we investigate whether features important for simplifying English text are similarly helpful for simplifying Spanish text. We conducted a user study on 15 Spanish medical texts using Amazon Mechanical Turk and measured perceived and actual difficulty. Using the median of the difficulty scores, we split the texts into easy and difficult groups and extracted 10 surface, 2 semantic and 4 grammatical features. Using t-tests, we identified those features that significantly distinguish easy text from difficult text in Spanish and compare with prior work in English. We found that easy Spanish texts use more repeated words and adverbs, less negations and more familiar words, similar to English. Also like English, difficult Spanish texts use more nouns and adjectives. However in contrast to English, easier Spanish texts contained longer sentences and used grammatical structures that were more varied. PMID:29854201
Spanish Readability Formulas for Elementary-Level Texts: A Validation Study.
ERIC Educational Resources Information Center
Parker, Richard I.; Hasbrouck, Jan E.; Weaver, Laurie
2001-01-01
Uses two formulas developed for Spanish language text to analyze 9 stories that were read by 36 Spanish-speaking second graders with limited English proficiency. Finds that the Spanish readability formulas only weakly predicted student performance, indicating the need to pursue broader, qualitative indices of difficulty for Spanish text. (SG)
2012-01-01
Background The benzoxazinoids 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) and 2,4-dihydroxy-7- methoxy-1,4-benzoxazin-3-one (DIMBOA), are key defense compounds present in major agricultural crops such as maize and wheat. Their biosynthesis involves nine enzymes thought to form a linear pathway leading to the storage of DI(M)BOA as glucoside conjugates. Seven of the genes (Bx1-Bx6 and Bx8) form a cluster at the tip of the short arm of maize chromosome 4 that includes four P450 genes (Bx2-5) belonging to the same CYP71C subfamily. The origin of this cluster is unknown. Results We show that the pathway appeared following several duplications of the TSA gene (α-subunit of tryptophan synthase) and of a Bx2-like ancestral CYP71C gene and the recruitment of Bx8 before the radiation of Poaceae. The origins of Bx6 and Bx7 remain unclear. We demonstrate that the Bx2-like CYP71C ancestor was not committed to the benzoxazinoid pathway and that after duplications the Bx2-Bx5 genes were under positive selection on a few sites and underwent functional divergence, leading to the current specific biochemical properties of the enzymes. The absence of synteny between available Poaceae genomes involving the Bx gene regions is in contrast with the conserved synteny in the TSA gene region. Conclusions These results demonstrate that rearrangements following duplications of an IGL/TSA gene and of a CYP71C gene probably resulted in the clustering of the new copies (Bx1 and Bx2) at the tip of a chromosome in an ancestor of grasses. Clustering favored cosegregation and tip chromosomal location favored gene rearrangements that allowed the further recruitment of genes to the pathway. These events, a founding event and elongation events, may have been the key to the subsequent evolution of the benzoxazinoid biosynthetic cluster. PMID:22577841
Dutartre, Leslie; Hilliou, Frédérique; Feyereisen, René
2012-05-11
The benzoxazinoids 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) and 2,4-dihydroxy-7- methoxy-1,4-benzoxazin-3-one (DIMBOA), are key defense compounds present in major agricultural crops such as maize and wheat. Their biosynthesis involves nine enzymes thought to form a linear pathway leading to the storage of DI(M)BOA as glucoside conjugates. Seven of the genes (Bx1-Bx6 and Bx8) form a cluster at the tip of the short arm of maize chromosome 4 that includes four P450 genes (Bx2-5) belonging to the same CYP71C subfamily. The origin of this cluster is unknown. We show that the pathway appeared following several duplications of the TSA gene (α-subunit of tryptophan synthase) and of a Bx2-like ancestral CYP71C gene and the recruitment of Bx8 before the radiation of Poaceae. The origins of Bx6 and Bx7 remain unclear. We demonstrate that the Bx2-like CYP71C ancestor was not committed to the benzoxazinoid pathway and that after duplications the Bx2-Bx5 genes were under positive selection on a few sites and underwent functional divergence, leading to the current specific biochemical properties of the enzymes. The absence of synteny between available Poaceae genomes involving the Bx gene regions is in contrast with the conserved synteny in the TSA gene region. These results demonstrate that rearrangements following duplications of an IGL/TSA gene and of a CYP71C gene probably resulted in the clustering of the new copies (Bx1 and Bx2) at the tip of a chromosome in an ancestor of grasses. Clustering favored cosegregation and tip chromosomal location favored gene rearrangements that allowed the further recruitment of genes to the pathway. These events, a founding event and elongation events, may have been the key to the subsequent evolution of the benzoxazinoid biosynthetic cluster.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-10
... Chapter XV, Section 2 entitled ``BX Options Market--Fees and Rebates'' to adopt rebates and fees relating... approval to operate a new options market.\\3\\ The new market, called NASDAQ OMX BX Options, or BX Options... rebates and fees for Customers, BX Options Market Makers \\4\\ and Non-Customers \\5\\ in various options \\6...
The Cultural Content of Business Spanish Texts.
ERIC Educational Resources Information Center
Grosse, Christine Uber; Uber, David
1992-01-01
Eight business Spanish texts were examined to learn about the cultural content of the business Spanish curriculum. Questions of cultural topics and themes, presentation of cultural information, activities and techniques, and use of authentic materials were considered. (16 references) (LB)
"Ficciones," Jorge Luis Borges. Performance Guides to Spanish Texts.
ERIC Educational Resources Information Center
Gies, David Thatcher, Comp.
This performance guide is the result of work conducted at the University of Virginia's National Endowment for the Humanities Summer Institute, 1989, on "Spanish Literature in Performance," in which 25 secondary school Spanish teachers studied Spanish texts from the perspective of classroom performance to deepen knowledge of the texts and…
Li, Yong; Wu, Changqiang; Chen, Tianwu; Zhang, Juanjuan; Liu, Gang; Pu, Yu; Zhu, Jiang; Shen, Chengyi; Zhang, Yang; Zeng, Nanlin; Zhang, Xiaoming
2016-12-01
It was previously demonstrated that mucin 4 (MUC4) is not expressed in normal pancreatic tissues or in chronic pancreatitis tissue but is highly expressed in pancreatic cancer (PC) tissue. Effective MUC4 gene knockdown in PC may contribute to the elucidation of pancreatic tumor development and metastasis, and may be valuable in new therapeutic approaches. Thus to confirm this, in the present study, the BxPC-3 cell line was transfected with eight pairs of shRNA lentiviral vectors for MUC4. The qPCR results showed that expression of MUC4 mRNA in the BxPC-3 cells was significantly decreased at 96 h after transfection. One of these shRNA lentiviral vectors (shRNA‑A141) had showed the strongest suppressive effect on MUC4 mRNA expression and was used for MUC4 knockdown in BxPC-3 cells. After stable transfection, BxPC-3 cells showed a significantly lower expression of MUC4 mRNA and MUC4 protein, and were suppressed on cell growth and migration. In vivo, lower tumor growth rates and tumor volume were observed in the tumors derived from the MUC4-knockdown cells, whereas the transplanted tumors derived from the control group cells, grew rapidly. Thus, inhibition of MUC4 expression may be an effective means for mitigating metastasis and invasion of PC.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-27
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-68268; File No. SR-BX-2012-072] Self-Regulatory... Securities Exchange Act of 1934 (``Act'') \\1\\ and Rule 19b-4 thereunder,\\2\\ notice is hereby given that on November 15, 2012, NASDAQ OMX BX, Inc. (``BX'' or the ``Exchange'') filed with the Securities and Exchange...
Ase, Ariel R; Honson, Nicolette S; Zaghdane, Helmi; Pfeifer, Tom A; Séguéla, Philippe
2015-04-01
P2X4 is an ATP-gated nonselective cation channel highly permeable to calcium. There is increasing evidence that this homomeric purinoceptor, which is expressed in several neuronal and immune cell types, is involved in chronic pain and inflammation. The current paucity of unambiguous pharmacological tools available to interrogate or modulate P2X4 function led us to pursue the search for selective antagonists. In the high-throughput screen of a compound library, we identified the phenylurea BX430 (1-(2,6-dibromo-4-isopropyl-phenyl)-3-(3-pyridyl)urea, molecular weight = 413), with antagonist properties on human P2X4-mediated calcium uptake. Patch-clamp electrophysiology confirmed direct inhibition of P2X4 currents by extracellular BX430, with submicromolar potency (IC50 = 0.54 µM). BX430 is highly selective, having virtually no functional impact on all other P2X subtypes, namely, P2X1-P2X3, P2X5, and P2X7, at 10-100 times its IC50. Unexpected species differences were noticed, as BX430 is a potent antagonist of zebrafish P2X4 but has no effect on rat and mouse P2X4 orthologs. The concentration-response curve for ATP on human P2X4 in the presence of BX430 shows an insurmountable blockade, indicating a noncompetitive allosteric mechanism of action. Using a fluorescent dye uptake assay, we observed that BX430 also effectively suppresses ATP-evoked and ivermectin-potentiated membrane permeabilization induced by P2X4 pore dilation. Finally, in single-cell calcium imaging, we validated its selective inhibitory effects on native P2X4 channels at the surface of human THP-1 cells that were differentiated into macrophages. In summary, this ligand provides a novel molecular probe to assess the specific role of P2X4 in inflammatory and neuropathic conditions, where ATP signaling has been shown to be dysfunctional. Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics.
Formation Process of Non-Neutral Plasmas by Multiple Electron Beams on BX-U
NASA Astrophysics Data System (ADS)
Sanpei, Akio; Himura, Haruhiko; Masamune, Sadao
An imaging diagnostic system, which is composed of a handmade phosphor screen and a high-speed camera, has been applied to identify the dynamics of multiple electron beams on BX-U. The relaxation process of those toward a non-neutral plasma is experimentally identified. Also, the radial density profile of the plasma is measured as a function of time. Assuming that the plasma is a spheroidal shape, the value of electron density ne is in the range between 2.2 × 106 and 4.4 × 108 cm-3 on BX-U.
Bakera, Beata; Makowska, Bogna; Groszyk, Jolanta; Niziołek, Michał; Orczyk, Wacław; Bolibok-Brągoszewska, Hanna; Hromada-Judycka, Aneta; Rakoczy-Trojanowska, Monika
2015-08-01
Benzoxazinoids (BX) are major secondary metabolites of gramineous plants that play an important role in disease resistance and allelopathy. They also have many other unique properties including anti-bacterial and anti-fungal activity, and the ability to reduce alfa-amylase activity. The biosynthesis and modification of BX are controlled by the genes Bx1 ÷ Bx10, GT and glu, and the majority of these Bx genes have been mapped in maize, wheat and rye. However, the genetic basis of BX biosynthesis remains largely uncharacterized apart from some data from maize and wheat. The aim of this study was to isolate, sequence and characterize five genes (ScBx1, ScBx2, ScBx3, ScBx4 and ScBx5) encoding enzymes involved in the synthesis of DIBOA, an important defense compound of rye. Using a modified 3D procedure of BAC library screening, seven BAC clones containing all of the ScBx genes were isolated and sequenced. Bioinformatic analyses of the resulting contigs were used to examine the structure and other features of these genes, including their promoters, introns and 3'UTRs. Comparative analysis showed that the ScBx genes are similar to those of other Poaceae species, especially to the TaBx genes. The polymorphisms present both in the coding sequences and non-coding regions of ScBx in relation to other Bx genes are predicted to have an impact on the expression, structure and properties of the encoded proteins.
Culture Curriculum for Spanish, Level 2.
ERIC Educational Resources Information Center
Cooper, Ina; Palumbo, Marilyn
This curriculum guide is presented as a supplement to the text "Learning Spanish the Modern Way, Book 2" (lessons 15-23). Topics included are designed for the level-2 program by the New York State syllabus and emphasize cultural aspects of life in Spain and Mexico. The importance of Spanish, geography of Mexico and Spain, Spanish influence in the…
The Cultural Content of Business Spanish Texts.
ERIC Educational Resources Information Center
Grosse, Christine Uber; Uber, David
A study examined eight business Spanish textbooks for cultural content by looking at commonly appearing cultural topics and themes, presentation of cultural information, activities and techniques used to promote cultural understanding, and incorporation of authentic materials. The texts were evenly divided among beginning, intermediate, and…
Li, Chunyan; Li, Yue; Cheng, Xiaosong; Feng, Liping; Xi, Chuanwu; Zhang, Ying
2013-03-01
In this study, a unique biofilm consisting of three bacterial strains with high biofilm-forming capability (Bacillus subtilis E2, E3, and N4) and an acetonitrile-degrading bacterium (Rhodococcus rhodochrous BX2) was established for acetonitrile-containing wastewater treatment. The results indicated that this biofilm exhibited strong resistance to acetonitrile loading shock and displayed a typical spatial and structural heterogeneity and completely depleted the initial concentration of acetonitrile (800mgL(-1)) within 24h in a moving-bed-biofilm reactor (MBBR) after operation for 30days. The immobilization of BX2 cells in the biofilm was confirmed by PCR-DGGE. It has been demonstrated that biofilm-forming bacteria can promote the immobilization of contaminant-degrading bacteria in the biofilms and can subsequently improve the degradation of contaminants in wastewater. This approach offers a novel strategy for enhancing biological oxidation of toxic pollutants in wastewater. Copyright © 2012 Elsevier Ltd. All rights reserved.
"Historias de la Artamila," Ana Maria Matute. Performance Guides to Spanish Texts.
ERIC Educational Resources Information Center
Gies, David Thatcher, Comp.
This performance guide is the result of work conducted at the University of Virginia's National Endowment for the Humanities Summer Institute, 1989, on "Spanish Literature in Performance," in which 25 secondary school Spanish teachers studied Spanish texts from the perspective of classroom performance to deepen knowledge of the texts and…
ERIC Educational Resources Information Center
Lazarte, Alejandro A.; Barry, Sue
2008-01-01
In Experiment 1, monolingual native Spanish speakers (NSSs) had better kernel recall and longer end-of-clause (EOC) pauses than native English speakers (NESs) when reading texts that varied in syntactic complexity as a function of the number of nonessential clauses added to the kernel text. NSS familiarity with embedded clauses in Spanish seem to…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-18
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-71055; File No. SR-BX-2013-059] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To... of 1934 (``Act'') \\1\\ and Rule 19b-4 thereunder,\\2\\ notice is hereby given that on November 29, 2013...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-14
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-69071; File No. SR-BX-2013-020] Self-Regulatory... Amend Chapter V, Regulation of Trading on BX Options, Section 6, Obvious Errors March 7, 2013. Pursuant.... 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of Substance...
Guo, Xiao-Hui; Bi, Zhe-Guang; Wu, Bi-Hua; Wang, Zhen-Zhen; Hu, Ji-Liang; Zheng, You-Liang; Liu, Deng-Cai
2013-12-01
High-molecular-weight glutenin subunits (HMW-GSs) are of considerable interest, because they play a crucial role in determining dough viscoelastic properties and end-use quality of wheat flour. In this paper, ChAy/Bx, a novel chimeric HMW-GS gene from Triticum turgidum ssp. dicoccoides (AABB, 2n=4x=28) accession D129, was isolated and characterized. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) analysis revealed that the electrophoretic mobility of the glutenin subunit encoded by ChAy/Bx was slightly faster than that of 1Dy12. The complete ORF of ChAy/Bx contained 1,671 bp encoding a deduced polypeptide of 555 amino acid residues (or 534 amino acid residues for the mature protein), making it the smallest HMW-GS gene known from Triticum species. Sequence analysis showed that ChAy/Bx was neither a conventional x-type nor a conventional y-type subunit gene, but a novel chimeric gene. Its first 1305 nt sequence was highly homologous with the corresponding sequence of 1Ay type genes, while its final 366 nt sequence was highly homologous with the corresponding sequence of 1Bx type genes. The mature ChAy/Bx protein consisted of the N-terminus of 1Ay type subunit (the first 414 amino acid residues) and the C-terminus of 1Bx type subunit (the final 120 amino acid residues). Secondary structure prediction showed that ChAy/Bx contained some domains of 1Ay subunit and some domains of 1Bx subunit. The special structure of this HMW glutenin chimera ChAy/Bx subunit might have unique effects on the end-use quality of wheat flour. Here we propose that homoeologous recombination might be a novel pathway for allelic variation or molecular evolution of HMW-GSs. © 2013.
"Veinte poemas de amor y Canto general," Pablo Neruda. Performance Guides to Spanish Texts.
ERIC Educational Resources Information Center
Gies, David Thatcher, Comp.
This performance guide is the result of work conducted at the University of Virginia's National Endowment for the Humanities Summer Institute, 1989, on "Spanish Literature in Performance," in which 25 secondary school Spanish teachers studied Spanish texts from the perspective of classroom performance to deepen knowledge of the texts and…
ERIC Educational Resources Information Center
Kim, Young-Suk
2012-01-01
We investigated the relations of L2 (i.e., English) oral reading fluency, silent reading fluency, word reading automaticity, oral language skills, and L1 literacy skills (i.e., Spanish) to L2 reading comprehension for Spanish-speaking English language learners in the first grade (N = 150). An analysis was conducted for the entire sample as well as…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-25
... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change... OMX BX, Inc. (``BX'' or ``Exchange'') filed with the Securities and Exchange Commission (``SEC'' or... Act \\6\\ in general, and furthers the objectives of Section 6(b)(4) of the Act,\\7\\ in particular, in...
NASA Astrophysics Data System (ADS)
Sikorska, Celina; Skurski, Piotr
2010-11-01
The explanation of the MgBX 5 (X = F, Cl) systems existence and stability is provided on the basis of theoretical considerations supported by ab initio calculations. The equilibrium structures and most probable fragmentation processes of 26 (including isomers) MgBX 5 molecules and six OBX 5 compounds (for comparison) were examined and discussed. The competition between the ionization potential (IP) of the MgX subunit and the electron binding energy (VDE) of the BX 4 fragment was found to be the key factor determining the ability to form a stable compound of MgBX 5 type.
Ragupathy, Raja; Naeem, Hamid A; Reimer, Elsa; Lukow, Odean M; Sapirstein, Harry D; Cloutier, Sylvie
2008-01-01
Sequencing of a BAC clone encompassing the Glu-B1 locus in Glenlea, revealed a 10.3 Kb segmental duplication including the Bx7 gene and flanking an LTR retroelement. To better understand the evolution of this locus, two collections of wheat were surveyed. The first consisted of 96 diploid and tetraploid species accessions while the second consisted of 316 Triticum aestivum cultivars and landraces from 41 countries. The genotypes were first characterized by SDS-PAGE and a total of 40 of the 316 T. aestivum accessions were found to display the overexpressed Bx7 phenotype (Bx7OE). Three lines from the 96 diploid/tetraploid collection also displayed the stronger intensity staining characteristic of the Bx7(OE) subunit. The relative amounts of the Bx7 subunit to total HMW-GS were quantified by RP-HPLC for all Bx7OE accessions and a number of checks. The entire collection was assessed for the presence of four DNA markers namely an 18 bp indel of the coding region of Bx7 variant alleles, a 43 bp indel of the 5'-region and the left and right junctions of the LTR retrotransposon borders and the duplicated segment. All 43 accessions found to have the Bx7OE subunit by SDS-PAGE and RP-HPLC produced the four diagnostic PCR amplicons. None of the lines without the Bx7OE had the LTR retroelement/duplication genomic structure. However, the 18 and 43 bp indel were found in accessions other than Bx7OE. These results indicate that the overexpression of the Bx7 HMW-GS is likely the result of a single event, i.e., a gene duplication at the Glu-B1 locus mediated by the insertion of a retroelement. Also, the 18 and 43 bp indels pre-date the duplication event. Allelic variants Bx7*, Bx7 with and without 43 bp insert and Bx7OE were found in both tetraploid and hexaploid collections and shared the same genomic organization. Though the possibility of introgression from T. aestivum to T. turgidum cannot be ruled out, the three structural genomic changes of the B-genome taken together support
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-14
... Chapter XV, Section 2 entitled ``BX Options Market--Fees and Rebates'' to amend rebates and fees relating... Chapter XV, Section 2(1) to amend rebates and fees for Customers, BX Options Market Makers \\3\\ and Non... below,\\6\\ as follows: \\3\\ A BX Options Market Makers must be registered as such pursuant to Chapter VII...
Enhanced tumor targeting of cRGD peptide-conjugated albumin nanoparticles in the BxPC-3 cell line.
Yu, Xinzhe; Song, Yunlong; Di, Yang; He, Hang; Fu, Deliang; Jin, Chen
2016-08-12
The emerging albumin nanoparticle brings new hope for the delivery of antitumor drugs. However, a lack of robust tumor targeting greatly limits its application. In this paper, cyclic arginine-glycine-aspartic-conjugated, gemcitabine-loaded human serum albumin nanoparticles (cRGD-Gem-HSA-NPs) were successfully prepared, characterized, and tested in vitro in the BxPC-3 cell line. Initially, 4-N-myristoyl-gemcitabine (Gem-C14) was formed by conjugating myristoyl to the 4-amino group of gemcitabine. Then, cRGD-HSA was synthesized using sulfosuccinimidyl-(4-N-maleimidomethyl)cyclohexane-1-carboxylate (Sulfo-SMCC) cross-linkers. Finally, cRGD-Gem-HSA-NPs were formulated based on the nanoparticle albumin-bound (nab) technology. The resulting NPs were characterized for particle size, zeta potential, morphology, encapsulation efficiency, and drug loading efficiency. In vitro cellular uptake and inhibition studies were conducted to compare Gem-HSA-NPs and cRGD-Gem-HSA-NPs in a human pancreatic cancer cell line (BxPC-3). The cRGD-Gem-HSA-NPs exhibited an average particle size of 160 ± 23 nm. The encapsulation rate and drug loading rate were approximately 83 ± 5.6% and 11 ± 4.2%, respectively. In vitro, the cRGD-anchored NPs exhibited a significantly greater affinity for the BxPC-3 cells compared to non-targeted NPs and free drug. The cRGD-Gem-HSA-NPs also showed the strongest inhibitory effect in the BxPC-3 cells among all the analyzed groups. The improved efficacy of cRGD-Gem-HSA-NPs in the BxPC-3 cell line warrants further in vivo investigations.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-03
... Exchange or NASDAQ Execution Services To Cancel Orders When a Technical or Systems Issue Occurs and To... the authority of BX or NASDAQ Execution Services (``NES'') to cancel orders when a technical or... issue may occur at BX, NES, or a routing destination that causes BX or NES to cancel orders, if BX or...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-02
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-62396; File No. SR-BX-2010-012] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving a Proposed Rule Change To Codify Prices for Co-Location Services June 28, 2010. I. Introduction On January 29, 2010, NASDAQ OMX BX, Inc. (``BX'' or ``Exchange...
Simultaneous CCD Photometry of Two Eclipsing Binary Stars in Pegasus - Part2: BX Peg
NASA Astrophysics Data System (ADS)
Alton, K. B.
2013-05-01
BX Peg is an overcontact W UMa binary system (P = 0.280416 d) which has been rather well studied, but not fully understood due to complex changes in eclipse timings and light curve variations attributed to star spots. Photometric data collected in three bandpasses (B, V, and Ic) produced nineteen new times of minimum for BX Peg. These were used to update the linear ephemeris and further analyze potential changes in orbital periodicity by examining long-term changes in eclipse timings. In addition, synthetic fitting of light curves by Roche modeling was accomplished with the assistance of three different programs, two of which employ the Wilson-Devinney code. Different spotted solutions were necessary to achieve the best Roche model fits for BX Peg light curves collected in 2008 and 2011. Overall, the long-;term decrease (9.66 × 10-3 sec y-1) in orbital period defined by the parabolic fit of eclipse timing data could arise from mass transfer or angular momentum loss. The remaining residuals from observed minus predicted eclipse timings for BX Peg exhibit complex but non-random behavior. These may be related to magnetic activity cycles and/or the presence of an unseen mass influencing the times of minimum, however, additional minima need to be collected over a much longer timescale to resolve the nature of these complex changes.
Passuni, Diego; Dalzotto, Elisa; F Gath, Christian; Buffetti, Eliana; Elizalde, Milagros; Jarmoluk, Verónica; Russo, Maria J; Intruvini, Silvia; Olmos, Lisandro E; Freixes, Orestes
2018-05-03
Cross-sectional. The majority of people with a spinal cord injury (SCI) are dependent on wheelchair for their mobility. Approximately, 36% of wheelchair users reported that obstacles such as curbs, uneven terrain, flooring surfaces and thresholds were barriers to mobility. Several studies have shown that assessment and training of wheelchair skills leads to improvements in those skills. The purpose of our study was to translate the Wheelchair Skill Test (4.2) and its report form into Spanish and then determine the inter-rater reliability of the WST 4.2 for manual wheelchairs operated by their users. Rehabilitation Unit, FLENI Institute, Buenos Aires, Argentina. The translation was performed by a physical therapist with advanced English language skills and specialized in the treatment of SCI subjects. We administrated and video-recorded the WST 4.2 manual Spanish version in 11 SCI subjects. Two physical therapists received specific training for administering the test and scoring the record. The reliability of the total percentage WST score were statistically quantified by intraclass correlation coefficient (ICC). ICC values for Interrater were 0.998 (p < .0001). 17 out of the 32 skills had a 100 percentage of agreement. Percentage of agreement in the three skills that presented less rating agreement was 73%, 81 % and 82 %, respectively. The results show that the Spanish version of WST 4.2 is a reliable assessment tool to evaluate the skills capacity of spinal cord manual wheelchair users. Implications for rehabilitation Wheelchair users require a proficient management of various wheelchair skills to achieve maximum independence in daily life. Determining which wheelchair skills should be addressed during the rehabilitation process is of great importance for their correct training. The WST 4.2 is an appropriate assessment tool to determine the functional capacity of wheelchair users. Making available the WST 4.2 in the Spanish language and demonstrating its
Isolation and divalent-metal activation of a ß-xylosidase, RUM630-BX
USDA-ARS?s Scientific Manuscript database
The gene encoding RUM630-BX, a ß-xylosidase/arabinofuranosidase, was identified from activity-based screening of a cow rumen metagenomic library. The recombinant enzyme is activated as much as 14-fold (kcat) by divalent metals Mg2+, Mn2+ and Co2+ but not by Ca2+, Ni2+, and Zn2+. Activation of RUM6...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-23
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-64090; File No. SR-BX-2011-007] Self-Regulatory Organizations; NASDAQ OMX BX LLC; Order Approving a Proposed Rule Change Relating to Permanent Approval of the BX and NES Inbound Routing Relationship March 17, 2011. I. Introduction On January 28, 2011, NASDAQ...
ERIC Educational Resources Information Center
Thompson, Mary P.; And Others
This is the second volume in a series of texts in a conversational Spanish course for elementary school children. Fourteen basic units present introductory linguistic patterns and cultural insights into the lives of the Spanish people. They include: (1) Review Unit 1, (2) Review Unit 2, (3) Special Unit A--"Cristobal Colon," (4) Review Unit 3, (5)…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-16
... 1934 (``Act''),\\1\\ and Rule 19b-4 thereunder,\\2\\ notice is hereby given that on October 31, 2012... proposed rule change from interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self... proposes to amend Chapter XV, Section 2 entitled ``BX Options Market--Fees and Rebates.'' Specifically, the...
Ulzurrun, Eugenia; Stephens, Camilla; Ruiz-Cabello, Francisco; Robles-Diaz, Mercedes; Saenz-López, Pablo; Hallal, Hacibe; Soriano, German; Roman, Eva; Fernandez, M Carmen; Lucena, M Isabel; Andrade, Raúl J
2014-01-01
Flawed ABC transporter functions may contribute to increased risk of drug-induced liver injury (DILI). We aimed to analyse the influence of genetic variations in ABC transporters on the risk of DILI development and clinical presentations in a large Spanish DILI cohort. A total of ten polymorphisms in ABCB1 (1236T>C, 2677G>T,A, 3435T>C), ABCB4 (1954A>G) and ABCC2 (-1774G>del, -1549A>G, -24C>T, 1249G>A, 3972C>T and 4544G>A) were genotyped using Taqman 5' allelic discrimination assays or sequencing in 141 Spanish DILI patients and 161 controls. The influence of specific genotypes, alleles and haplotypes on the risk of DILI development and clinical presentations was analysed. None of the individual polymorphisms or haplotypes was found to be associated with DILI development. Carriers homozygous for the ABCC2 -1774del allele were however only found in DILI patients. Hence, this genotype could potentially be associated with increased risk, though its low frequency in our Spanish cohort prevented a final conclusion. Furthermore, carriers homozygous for the ABCC2 -1774G/-1549A/-24T/1249G/3972T/4544G haplotype were found to have a higher propensity for total bilirubin elevations when developing DILI. Our findings do not support a role for the analysed polymorphisms in the ABCB1, ABCB4 and ABCC2 transporter genes in DILI development in Spanish patients. The ABCC2 -1774deldel genotype was however restricted to DILI cases and could potentially contribute to enhanced DILI susceptibility.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-08
... attached as Exhibit 2.\\3\\ \\3\\ The Commission notes that the text of the proposed Regulatory Circular is... Exchange Act Release No. 60886 (October 27, 2009), 74 FR 56897 (November 3, 2009) (SR-BX-2009-067). This..., February 1, 2010, May 3, 2010 and August 2, 2010, respectively. For purposes of identifying the classes to...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-08
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-66306; File No. SR-BX-2011-084] Self-Regulatory... the Price Improvement Period (``PIP'') From One Second to One Hundred Milliseconds February 2, 2012. I...\\ and Rule 19b-4 thereunder,\\2\\ a proposed rule change to reduce the duration of the Price Improvement...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-27
... described in the Exchange's option rules at subsection (a)(3)(A) of Chapter VI, Section 1 as a data package... (a)(3)(B) of Chapter VI, Section 1 as a data package that includes the BX Best Bid and Offer (``BX... for options market data known as BX Top of Market Options (``BX Top'') and BX Depth of Market Options...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-18
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-63907; File No. SR-BX-2011-008] Self-Regulatory Organizations; NASDAQ OMX BX; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change To Establish and Adopt Fees for the New Short Sale Monitor Service and BX Data Add-On February 14, 2011. Pursuant to Section 19(b)(1) of the...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-07
... Relating to Permitting Concurrent Listing of $3.50 and $4 Strikes for Classes in the $0.50 Strike and $1... (``Act''),\\1\\ and Rule 19b-4 \\2\\ thereunder, notice is hereby given that on March 30, 2010, NASDAQ OMX BX... interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. \\3\\ 15 U.S.C. 78s(b)(3)(A). \\4\\ 17 CFR 240...
Identification and VIGS-based characterization of Bx1 ortholog in rye (Secale cereale L.)
Groszyk, Jolanta; Kowalczyk, Mariusz; Yanushevska, Yuliya; Stochmal, Anna; Rakoczy-Trojanowska, Monika
2017-01-01
The first step of the benzoxazinoid (BX) synthesis pathway is catalyzed by an enzyme with indole-3-glycerol phosphate lyase activity encoded by 3 genes, Bx1, TSA and Igl. A gene highly homologous to maize and wheat Bx1 has been identified in rye. The goal of the study was to analyze the gene and to experimentally verify its role in the rye BX biosynthesis pathway as a rye ortholog of the Bx1 gene. Expression of the gene showed peak values 3 days after imbibition (dai) and at 21 dai it was undetectable. Changes of the BX content in leaves were highly correlated with the expression pattern until 21 dai. In plants older than 21 dai despite the undetectable expression of the analyzed gene there was still low accumulation of BXs. Function of the gene was verified by correlating its native expression and virus-induced silencing with BX accumulation. Barley stripe mosaic virus (BSMV)-based vectors were used to induce transcriptional (TGS) and posttranscriptional (PTGS) silencing of the analyzed gene. Both strategies (PTGS and TGS) significantly reduced the transcript level of the analyzed gene, and this was highly correlated with lowered BX content. Inoculation with virus-based vectors specifically induced expression of the analyzed gene, indicating up-regulation by biotic stressors. This is the first report of using the BSMV-based system for functional analysis of rye gene. The findings prove that the analyzed gene is a rye ortholog of the Bx1 gene. Its expression is developmentally regulated and is strongly induced by biotic stress. Stable accumulation of BXs in plants older than 21 dai associated with undetectable expression of ScBx1 indicates that the function of the ScBx1 in the BX biosynthesis is redundant with another gene. We anticipate that the unknown gene is a putative ortholog of the Igl, which still remains to be identified in rye. PMID:28234909
Identification and VIGS-based characterization of Bx1 ortholog in rye (Secale cereale L.).
Groszyk, Jolanta; Kowalczyk, Mariusz; Yanushevska, Yuliya; Stochmal, Anna; Rakoczy-Trojanowska, Monika; Orczyk, Waclaw
2017-01-01
The first step of the benzoxazinoid (BX) synthesis pathway is catalyzed by an enzyme with indole-3-glycerol phosphate lyase activity encoded by 3 genes, Bx1, TSA and Igl. A gene highly homologous to maize and wheat Bx1 has been identified in rye. The goal of the study was to analyze the gene and to experimentally verify its role in the rye BX biosynthesis pathway as a rye ortholog of the Bx1 gene. Expression of the gene showed peak values 3 days after imbibition (dai) and at 21 dai it was undetectable. Changes of the BX content in leaves were highly correlated with the expression pattern until 21 dai. In plants older than 21 dai despite the undetectable expression of the analyzed gene there was still low accumulation of BXs. Function of the gene was verified by correlating its native expression and virus-induced silencing with BX accumulation. Barley stripe mosaic virus (BSMV)-based vectors were used to induce transcriptional (TGS) and posttranscriptional (PTGS) silencing of the analyzed gene. Both strategies (PTGS and TGS) significantly reduced the transcript level of the analyzed gene, and this was highly correlated with lowered BX content. Inoculation with virus-based vectors specifically induced expression of the analyzed gene, indicating up-regulation by biotic stressors. This is the first report of using the BSMV-based system for functional analysis of rye gene. The findings prove that the analyzed gene is a rye ortholog of the Bx1 gene. Its expression is developmentally regulated and is strongly induced by biotic stress. Stable accumulation of BXs in plants older than 21 dai associated with undetectable expression of ScBx1 indicates that the function of the ScBx1 in the BX biosynthesis is redundant with another gene. We anticipate that the unknown gene is a putative ortholog of the Igl, which still remains to be identified in rye.
Ulzurrun, Eugenia; Stephens, Camilla; Ruiz-Cabello, Francisco; Robles-Diaz, Mercedes; Saenz-López, Pablo; Hallal, Hacibe; Soriano, German; Roman, Eva; Fernandez, M. Carmen; Lucena, M. Isabel; Andrade, Raúl J.
2014-01-01
Background and Aims Flawed ABC transporter functions may contribute to increased risk of drug-induced liver injury (DILI). We aimed to analyse the influence of genetic variations in ABC transporters on the risk of DILI development and clinical presentations in a large Spanish DILI cohort. Methods A total of ten polymorphisms in ABCB1 (1236T>C, 2677G>T,A, 3435T>C), ABCB4 (1954A>G) and ABCC2 (−1774G>del, −1549A>G, −24C>T, 1249G>A, 3972C>T and 4544G>A) were genotyped using Taqman 5′ allelic discrimination assays or sequencing in 141 Spanish DILI patients and 161 controls. The influence of specific genotypes, alleles and haplotypes on the risk of DILI development and clinical presentations was analysed. Results None of the individual polymorphisms or haplotypes was found to be associated with DILI development. Carriers homozygous for the ABCC2 −1774del allele were however only found in DILI patients. Hence, this genotype could potentially be associated with increased risk, though its low frequency in our Spanish cohort prevented a final conclusion. Furthermore, carriers homozygous for the ABCC2 −1774G/−1549A/−24T/1249G/3972T/4544G haplotype were found to have a higher propensity for total bilirubin elevations when developing DILI. Conclusions Our findings do not support a role for the analysed polymorphisms in the ABCB1, ABCB4 and ABCC2 transporter genes in DILI development in Spanish patients. The ABCC2 −1774deldel genotype was however restricted to DILI cases and could potentially contribute to enhanced DILI susceptibility. PMID:24732756
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-29
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-69232; File No. SR-BX-2013-013] Self-Regulatory.... Introduction On February 6, 2013, NASDAQ OMX BX, Inc. (``Exchange'' or ``BX'') filed with the Securities and Exchange Commission (``Commission''), pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934...
Stress-Induced Acoustic Variation in L2 and L1 Spanish Vowels.
Romanelli, Sofía; Menegotto, Andrea; Smyth, Ron
2018-05-28
We assessed the effect of lexical stress on the duration and quality of Spanish word-final vowels /a, e, o/ produced by American English late intermediate learners of L2 Spanish, as compared to those of native L1 Argentine Spanish speakers. Participants read 54 real words ending in /a, e, o/, with either final or penultimate lexical stress, embedded in a text and a word list. We measured vowel duration and both F1 and F2 frequencies at 3 temporal points. stressed vowels were longer than unstressed vowels, in Spanish L1 and L2. L1 and L2 Spanish stressed /a/ and /e/ had higher F1 values than their unstressed counterparts. Only the L2 speakers showed evidence of rising offglides for /e/ and /o/. The L2 and L1 Spanish vowel space was compressed in the absence of stress. Lexical stress affected the vowel quality of L1 and L2 Spanish vowels. We provide an up-to-date account of the formant trajectories of Argentine River Plate Spanish word-final /a, e, o/ and offer experimental support to the claim that stress affects the quality of Spanish vowels in word-final contexts. © 2018 S. Karger AG, Basel.
El idioma espanol en el mundo (The Spanish Language in the World)
ERIC Educational Resources Information Center
Baron Castro, Rodolfo
1975-01-01
This report to the Office of Ibero-American Education concerns the status of Spanish in five areas: 1) A program on Spanish in the Philippines; 2) Spanish in the United States; 3) Cooperation with the Commission on Spanish of UNESCO; 4) A professorship in Bogota, and 5) Spanish scientific terminology. (Text is in Spanish.) (CHK)
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-03
... making activities at the Exchange which results in tighter markets and order interaction and benefits all... Participant commits himself to various obligations. Transactions of a Market Maker in its market making... The Exchange proposes to amend BX Options Rules, Chapter XV, Section 2 entitled ``BX Options Market...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-02
... expiration months and thus encourage competition without harming investors or the public interest. B. Self... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-65642; File No. SR-BX-2011-072] Self-Regulatory.... 78s(b)(1). \\2\\ 17 CFR 240.19b-4. \\3\\ 17 CFR 240.19b-4(f)(6). I. Self-Regulatory Organization's...
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2012-04-09
... a particular venue to be excessive. In such an environment, BX must continually adjust its fees to... execution and routing services offered by BX, if BX increases its fees to an excessive extent, it will lose customers to its competitors. Accordingly, BX believes that competitive market forces help to ensure that...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-14
... Modify Pricing for BX Members Using the NASDAQ OMX BX Equities System December 8, 2011. Pursuant to... of the Proposed Rule Change The Exchange proposes to modify pricing for BX Members using the NASDAQ... above $1. BX has a pricing model under which members are charged for the execution of quotes/orders...
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2011-08-26
... Establish and Adopt Fees for the New BX Pre-Trade Risk Management Service August 19, 2011. Pursuant to... Change The Exchange proposes to establish and adopt fees for the new BX Pre-Trade Risk Management service.... * * * * * 7016. [Reserved] BX Pre-Trade Risk Management (a) Users of BX Pre-trade Risk Management (``PRM'') will...
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2011-01-25
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-63731; File No. SR-BX-2010-083] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving a Proposed Rule Change Relating to the Price Improvement... (``BOX'') to permit an Options Participant initiating a Price Improvement Period (``PIP'') to designate a...
NASA Astrophysics Data System (ADS)
Slanger, T. G.; Pejaković, D. A.; Kostko, O.; Matsiev, D.; Kalogerakis, K. S.
2017-03-01
The terrestrial dayglow displays prominent emission features from the 0-0 and 1-1 bands of the O2 Atmospheric band system in the 760-780 nm region. We present an analysis of observations in this wavelength region recorded by the Space Shuttle during the Arizona Airglow Experiment. A major conclusion is that the dominant product of O(1D) + O2 energy transfer is O2(b, v = 1), a result that corroborates our previous laboratory studies. Moreover, critical to the interpretation of dayglow is the possible interference by N2 and N2+ bands in the 760-780 nm region, where the single-most important component is the N2 1PG 3-1 band that overlaps with the O2(b-X) 0-0 band. When present, this background must be accounted for to reveal the O2(b-X) 0-0 and 1-1 bands for altitudes at which the O2 and N2/N2+ emissions coincide. Finally, we exploit the very different collisional behavior of the two lowest O2(b) vibrational levels to outline a remote sensing technique that provides information on Atmospheric composition and temperature from space-based observations of the 0-0 and 1-1 O2 atmospheric bands.
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2012-05-18
... operate the BX Options market. BX's history dates back to the 1830s. For many years, the Boston Stock... OMX BX. BX re-launched an equities marketplace utilizing state of the art NASDAQ technology, having...). Consistent with that storied history as a long-time competitor in the U.S. markets, BX now proposes to launch...
Bilingual Text4Walking Food Service Employee Intervention Pilot Study
Ingram, Diana; Wilbur, JoEllen; Fogg, Louis; Sandi, Giselle; Moss, Angela; Ocampo, Edith V
2016-01-01
Background Half of all adults in the United States do not meet the level of recommended aerobic physical activity. Physical activity interventions are now being conducted in the workplace. Accessible technology, in the form of widespread usage of cell phones and text messaging, is available for promoting physical activity. Objective The purposes of this study, which was conducted in the workplace, were to determine (1) the feasibility of implementing a bilingual 12-week Text4Walking intervention and (2) the effect of the Text4Walking intervention on change in physical activity and health status in a food service employee population. Methods Before conducting the study reported here, the Text4Walking research team developed a database of motivational physical activity text messages in English. Because Hispanic or Latino adults compose one-quarter of all adults employed in the food service industry, the Text4Walking team translated the physical activity text messages into Spanish. This pilot study was guided by the Physical Activity Health Promotion Framework and used a 1-group 12-week pre- and posttest design with food service employees who self-reported as being sedentary. The aim of the study was to increase the number of daily steps over the baseline by 3000 steps. Three physical activity text messages were delivered weekly. In addition, participants received 3 motivational calls during the study. Results SPSS version 19.0 and R 3.0 were used to perform the data analysis. There were 33 employees who participated in the study (57.6% female), with a mean age of 43.7 years (SD 8.4). The study included 11 Hispanic or Latino participants, 8 of whom requested that the study be delivered in Spanish. There was a 100% retention rate in the study. At baseline, the participants walked 102 (SD 138) minutes/day (per self-report). This rate increased significantly (P=.008) to 182 (SD 219) minutes/day over the course of the study. The participants had a baseline mean of 10
Bilingual Text4Walking Food Service Employee Intervention Pilot Study.
Buchholz, Susan Weber; Ingram, Diana; Wilbur, JoEllen; Fogg, Louis; Sandi, Giselle; Moss, Angela; Ocampo, Edith V
2016-06-01
Half of all adults in the United States do not meet the level of recommended aerobic physical activity. Physical activity interventions are now being conducted in the workplace. Accessible technology, in the form of widespread usage of cell phones and text messaging, is available for promoting physical activity. The purposes of this study, which was conducted in the workplace, were to determine (1) the feasibility of implementing a bilingual 12-week Text4Walking intervention and (2) the effect of the Text4Walking intervention on change in physical activity and health status in a food service employee population. Before conducting the study reported here, the Text4Walking research team developed a database of motivational physical activity text messages in English. Because Hispanic or Latino adults compose one-quarter of all adults employed in the food service industry, the Text4Walking team translated the physical activity text messages into Spanish. This pilot study was guided by the Physical Activity Health Promotion Framework and used a 1-group 12-week pre- and posttest design with food service employees who self-reported as being sedentary. The aim of the study was to increase the number of daily steps over the baseline by 3000 steps. Three physical activity text messages were delivered weekly. In addition, participants received 3 motivational calls during the study. SPSS version 19.0 and R 3.0 were used to perform the data analysis. There were 33 employees who participated in the study (57.6% female), with a mean age of 43.7 years (SD 8.4). The study included 11 Hispanic or Latino participants, 8 of whom requested that the study be delivered in Spanish. There was a 100% retention rate in the study. At baseline, the participants walked 102 (SD 138) minutes/day (per self-report). This rate increased significantly (P=.008) to 182 (SD 219) minutes/day over the course of the study. The participants had a baseline mean of 10,416 (SD 5097) steps, which also increased
Study of Historical 4B/X17 Mega Flare on 28 October 2003 (P58)
NASA Astrophysics Data System (ADS)
Uddin, W.; Chandra, R.; Ali, S. S.
2006-11-01
wuddin_99@yahoo.com We analysed multi-wavelength data of 28 October 2003 4B/X17.2 class extremely energetic parallel ribbon solar flare, which occurred in NOAA 10486. The flare was well observed in H-alpha at ARIES, Nainital and various space (SOHO, TRACE, RHESSI, WIND etc.) and ground based Observatories. The H-alpha observations show the stretching/detwisting and eruption of helically twisted S shaped (sigmoid) filament in the South-West direction of the active region with bright shock front followed by rapid increase in intensity and area of the gigantic flare. The flare is associated with a bright/fast full halo earth directed CME, strong type II, III and IV radio bursts, an intense proton event and GLE. It seems that the filament eruption triggered the halo CME because the helical structure is clearly visible in the SOHO/LASCO C2, C3 images. This indicates helicity transfer from chromosphere to corona and interplanetary medium. The magnetic field of the flaring region was most complex with high magnetic shear. From the above analysis we feel that the energy buildup/release process of this unique flare support helically twisted magnetic flux rope model.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-08
... Relating to Non-Penny Pilot Options Fees January 2, 2013. Pursuant to Section 19(b)(1) of the Securities...--Fees and Rebates'' to adopt fees and rebates for Non-Penny Pilot Options.\\3\\ \\3\\ Non-Penny Pilot refers... XV, Section 2(1) to adopt fees and rebates for Customers, BX Options Market Makers \\4\\ and Non...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-12
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-69343; File No. SR-BX-2013-026] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Granting Accelerated Approval of a Proposed Rule Change To Adopt... not be a true reflection of the value of the series being quoted. In response to these concerns, the...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-16
.... However, as the Commission has made clear with respect to BX's affiliate, the NASDAQ Stock Exchange LLC...: Manipulation patterns that monitor solely BX activity, including patterns that monitor activity that might... the opposite side of the BX market at an improved price (often referred to as ``odd lot manipulation...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-28
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-69607; File No. SR-BX-2013-029] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving Proposed Rule Change Relating to Board of Director Qualifications May 20, 2013. On March 27, 2013, NASDAQ OMX BX, Inc. (``BX'' or ``Exchange'') filed with the...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-10
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-62638; File No. SR-BX-2010-043] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving a Proposed Rule Change Relating to Pricing for Direct... establish pricing for 10Gb direct circuit connections and codify pricing for 1Gb direct circuit connections...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-19
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-69753; File No. SR-BX-2013-038] Self-Regulatory.... \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the... Public Reference Room. II. Self-Regulatory Organization's Statement of the Purpose of, and Statutory...
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2011-03-14
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-64059; File No. SR-BX-2011-013] Self-Regulatory... change from interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory... Exchange's principal office, and at the Commission's Public Reference Room. II. Self-Regulatory...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-08
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-65867; File No. SR-BX-2011-080] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Modify Its Optional Anti-Internalization Functionality December 2, 2011. Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934...
The Sightline to Q2343-BX415: Clues to Galaxy Formation in a Quasar Environment
NASA Astrophysics Data System (ADS)
Rix, Samantha A.; Pettini, Max; Steidel, Charles C.; Reddy, Naveen A.; Adelberger, Kurt L.; Erb, Dawn K.; Shapley, Alice E.
2007-11-01
We have discovered a strong DLA coincident in redshift with the faint QSO Q2343-BX415 (R=20.2, zem=2.57393). Follow-up observations at intermediate spectral resolution reveal that the metal lines associated with this proximate DLA (PDLA) consist of two sets of absorption components. One set is moving toward the quasar with velocities of ~150-600 km s-1 this gas is highly ionized and does not fully cover the continuum source, suggesting that it is physically close to the active nucleus. The other, which accounts for most of the neutral gas, is blueshifted relative to the QSO, with the strongest component at ~-160 km s-1. We consider the possibility that the PDLA arises in the outflowing interstellar medium of the host galaxy of Q2343-BX415, an interpretation supported by strong C IV and N V absorption at nearby velocities, and by the intense radiation field longward of the Lyman limit implied by the high C II*/H I ratio. If Q2343-BX415 is the main source of these UV photons, then the PDLA is located at either ~8 or ~37 kpc from the active nucleus. Alternatively, the absorber may be a foreground star-forming galaxy unrelated to the quasar and coincidentally at the same redshift, but our deep imaging and follow-up spectroscopy of the field of Q2343-BX415 has not yet produced a likely candidate. We measure the abundances of 14 elements in the PDLA, finding an overall metallicity of ~1/5 solar and a normal pattern of relative element abundances for this metallicity. Thus, in this PDLA there is no evidence for the supersolar metallicities that have been claimed for some proximate, high-ionization, systems. Based on data obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and NASA, and was made possible by the generous financial support of the W. M. Keck Foundation.
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2011-09-07
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-65226; File No. SR-BX-2011-059] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Change the Name of the BX Ouch BBO Feed to the BX MatchView Feed and To Modify Its Contents August 30, 2011. Pursuant to Section 19(b)(1) of...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-08
... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change To..., NASDAQ OMX BX, Inc. (``BX'' or ``Exchange'') filed with the Securities and Exchange Commission... market comprised of eleven U.S. options exchanges in which sophisticated and knowledgeable market...
Chen, Ru-Yi; Xu, Bin; Chen, Su-Feng; Chen, Si-Si; Zhang, Ting; Ren, Jun; Xu, Jian
2014-10-28
To investigate the effect of oridonin on nuclear transcription factors and to study the relationship between biological behavior and inflammatory factors in human pancreatic cancer (BxPC-3) cells. BxPC-3 cells were treated with various concentrations of oridonin, and viability curves were generated to test for inhibitory effects of the drug on cells. The expression of cytokines such as interleukin-1β (IL-1β), IL-6, or IL-33 was detected in BxPC-3 cell supernatants using an enzyme-linked immunosorbent assay (ELISA), and the protein expression of nuclear transcription factors including nuclear factor κB, activating protein-1, signal transducer and activator of transcription 3, bone morphogenetic protein 2, transforming growth factor β1 and sma and mad homologues in BxPC-3 cells was detected using Western blot. Carcinoma hallmark-related proteins such as survivin, vascular endothelial growth factor, and matrix metallopeptidase 2 were also detected using immunoblotting, and intra-nuclear IL-33 expression was detected using immunofluorescent staining. Treatment with oridonin reduced the viability of BxPC-3 cells in a dose dependent manner. The cells exhibited reduced growth following treatment with 8 μg/mL oridonin (13.05% ± 3.21%, P < 0.01), and the highest inhibitory ratio was 90.64% ± 0.70%, which was achieved with oridonin at a dose of 32 μg/mL. The IC50 value of oridonin in BxPC-3 cells was 19.32 μg/mL. ELISA analysis revealed that oridonin down-regulated the inflammatory factors IL-1β, IL-6, and IL-33 in a dose-dependent manner. IL-1β expression was significantly reduced in the 16 and 32 μg/mL treatment groups compared to the control group (12.97 ± 0.45 pg/mL, 11.17 ± 0.63 pg/mL vs 14.40 ± 0.38 pg/mL, P < 0.01). Similar trends were observed for IL-6 expression, which was significantly reduced in the 16 and 32 μg/mL treatment groups compared to the control group (4.05 ± 0.14 pg/mL vs 4.45 ± 0.43 pg/mL, P < 0.05; 3.95 ± 0.13 pg/mL vs 4.45 ± 0
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-02
... Eliminate Certain Rule Text Which Has Been Made Unnecessary Due to the Decommissioning of the OCC Hub June... text which has been made unnecessary due to the decommissioning of the Options Clearing Corporation (``OCC'') Hub. The text of the proposed rule change is available on BX's Web site, on the Commission's...
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2011-07-20
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-64886; File No. SR-BX-2011-042] Self-Regulatory... change from interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory....gov . II. Self-Regulatory Organization's Statement of the Purpose of, and Statutory Basis for, the...
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2011-12-22
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-65987; File No. SR-BX-2011-084] Self-Regulatory... below, which Items have been prepared by the self-regulatory organization. The Commission is publishing...(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of Substance...
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2011-06-06
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-64570; File No. SR-BX-2011-029] Self-Regulatory...\\ 17 CFR 240.19b-4. \\3\\ 17 CFR 240.19b-4(f)(6). I. Self-Regulatory Organization's Statement of the... Reference Room, and at the Commission's Web site at http://www.sec.gov . II. Self-Regulatory Organization's...
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2013-04-02
... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change... OMX BX, Inc. (``BX'' or ``Exchange'') filed with the Securities and Exchange Commission (``SEC'' or... by the Exchange.\\7\\ \\3\\ In a previous rule filing, the Exchange discussed the manner in which it...
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2010-12-10
... sale and offering of securities. In addition, BX would not list any company that meets the quantitative... listing. BX has proposed the following quantitative listing standards for the initial listing of... of listing. BX has proposed the following quantitative listing standards for the initial listing of...
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2010-04-06
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-61805; File No. SR-BX-2010-022] Self-Regulatory... Relating to the Price Improvement Period March 31, 2010. Pursuant to Section 19(b)(1) of the Securities... change from interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory...
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2011-06-14
... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To... Exchange Commission (``Commission'') the proposed rule change as described in Items I, II and III below... comments on the proposed rule change from interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-02
... market makers on other exchanges will not have a negative effect on BX Options investors and traders... Relating to Elimination of Market Maker Pre-Opening Obligations on BX Options October 26, 2012. Pursuant to... Chapter VII, Section 6 (Market Maker Quotations), to eliminate market maker pre- opening obligations on BX...
ERIC Educational Resources Information Center
Brantmeier, Cindy; Hammadou Sullivan, JoAnn; Strube, Michael
2014-01-01
With 97 learners in an advanced Spanish course, the study examines the effects of textual enhancement adjuncts, prior subject knowledge, first language (L1) reading ability, and second language (L2) Spanish proficiency on L2 comprehension of scientific passages. Readings included two texts with two types of embedded questions: a pause or written…
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2011-10-06
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-65447; File No. SR-BX-2011-067] Self-Regulatory Organizations; NASDAQ OMX BX; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change To Provide an Optional Functionality for a BOX Options Participant To Prevent Its Market Maker or Proprietary Broker-Dealer Orders Entered in BOX...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-02
... Modify the Post-Only Order Type on BX Options July 27, 2012. Pursuant to Section 19(b)(1) of the... proposal for the BX Options market (``BX Options'') to add an additional feature to the Post-Only Order..., the Proposed Rule Change 1. Purpose A Post-Only Order is an order that will not remove liquidity from...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-06
... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To..., NASDAQ OMX BX, Inc. (``BX'' or ``Exchange'') filed with the Securities and Exchange Commission (``SEC... and regulatory requirements,\\7\\ which normally do not apply to other market participants. By...
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2011-02-14
... BX and NES Inbound Routing Relationship February 7, 2011. Pursuant to Section 19(b)(1) of the... Commission seeking permanent approval of the BX and NES routing relationship.\\7\\ The Exchange hereby seeks... relationship on a pilot basis. During this pilot period, BX committed to the following conditions: 1. The...
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2012-02-24
... proposing to make available to members the Trading and Compliance Data Package under BX Rule 7021 (``Data Package''). The Data Package allows member firms to obtain via NasdaqTrader.com information regarding their own historical quoting and trading activity on BX. The Data Package will provide BX Participants...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-28
... Permit BX Options To Accept Inbound Options Orders From NASDAQ OMX PHLX LLC and NASDAQ Options Market... permanent approval of the Exchange's pilot program that permits the BX Options System to accept inbound orders routed by Nasdaq Options Services LLC (``NOS'') from the NASDAQ OMX PHLX LLC (``PHLX'') and The...
ERIC Educational Resources Information Center
Nagle, Charles
2018-01-01
This study examined relationships between language learning motivation and the longitudinal development of second language (L2) pronunciation. Twenty-six English-speaking learners of Spanish recorded a simplified picture description task 5 times over a year-long period spanning their 2nd, 3rd, and 4th semesters of Spanish language instruction.…
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2013-03-20
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-69140; File No. SR-BX-2013-026] Self-Regulatory... I, II and III below, which Items have been prepared by the self-regulatory organization. The.... \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the...
Hao, Chenyang; Tang, Saijun; Zhang, Xueyong; Li, Tian
2014-01-01
To better understand the transcriptional regulation of high molecular weight glutenin subunit (HMW-GS) expression, we isolated four Glu-1Bx promoters from six wheat cultivars exhibiting diverse protein expression levels. The activities of the diverse Glu-1Bx promoters were tested and compared with β-glucuronidase (GUS) reporter fusions. Although all the full-length Glu-1Bx promoters showed endosperm-specific activities, the strongest GUS activity was observed with the 1Bx7OE promoter in both transient expression assays and stable transgenic rice lines. A 43 bp insertion in the 1Bx7OE promoter, which is absent in the 1Bx7 promoter, led to enhanced expression. Analysis of promoter deletion constructs confirmed that a 185 bp MITE (miniature inverted-repeat transposable element) in the 1Bx14 promoter had a weak positive effect on Glu-1Bx expression, and a 54 bp deletion in the 1Bx13 promoter reduced endosperm-specific activity. To investigate the effect of the 43 bp insertion in the 1Bx7OE promoter, a functional marker was developed to screen 505 Chinese varieties and 160 European varieties, and only 1Bx7-type varieties harboring the 43 bp insertion in their promoters showed similar overexpression patterns. Hence, the 1Bx7OE promoter should be important tool in crop genetic engineering as well as in molecular assisted breeding. PMID:25133580
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2013-12-27
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-71168; File No. SR-BX-2013-064] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change to Modify the Definition of ``System Securities'' in BX Rule 4751(b) December 20, 2013. Pursuant to Section 19(b)(1) of the Securities Exchange...
7 CFR 51.2732 - U.S. No. 2 Spanish.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 2 Spanish. 51.2732 Section 51.2732... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2732 U.S. No. 2 Spanish. “U.S. No. 2 Spanish” consists of shelled Spanish type peanut kernels which may be split or broken...
The Importance of Concept of Word in Text as a Predictor of Sight Word Development in Spanish
ERIC Educational Resources Information Center
Ford, Karen L.; Invernizzi, Marcia A.; Meyer, J. Patrick
2015-01-01
The goal of the current study was to determine whether Concept of Word in Text (COW-T) predicts later sight word reading achievement in Spanish, as it does in English. COW-T requires that children have beginning sound awareness, automatic recognition of letters and letter sounds, and the ability to coordinate these skills to finger point…
ERIC Educational Resources Information Center
Thompson, Mary P.; And Others
This is the first in a series of texts in a conversational Spanish course for elementary school children. Fifteen basic units present introductory linguistic patterns and cultural insights into the lives of Spaniards. They include: (1) Greetings, Identifications, and Farewells, (2) Some Classroom Objects and Instructions, (3) Colors, (4) More…
ERIC Educational Resources Information Center
Saalfeld, Anita K.
2012-01-01
The present study investigated the effects of training on the perception of Spanish stress, an important feature in the Spanish verbal morphology system. Participants were two intact classes of native English speakers enrolled in a six-week session of second-semester Spanish, as well as native English and native Spanish control groups. During the…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Al Sdran, N.; Najran University, Faculty of Sciences and Arts, Najran; Maiz, F., E-mail: fethimaiz@gmail.com
2016-06-15
The numerical solutions of the time independent Schrödinger equation of different one-dimensional potentials forms are sometime achieved by the asymptotic iteration method. Its importance appears, for example, on its efficiency to describe vibrational system in quantum mechanics. In this paper, the Airy function approach and the Numerov method have been used and presented to study the oscillator anharmonic potential V(x) = Ax{sup 2α} + Bx{sup 2}, (A>0, B<0), with (α = 2) for quadratic, (α =3) for sextic and (α =4) for octic anharmonic oscillators. The Airy function approach is based on the replacement of the real potential V(x) bymore » a piecewise-linear potential v(x), while, the Numerov method is based on the discretization of the wave function on the x-axis. The first energies levels have been calculated and the wave functions for the sextic system have been evaluated. These specific values are unlimited by the magnitude of A, B and α. It’s found that the obtained results are in good agreement with the previous results obtained by the asymptotic iteration method for α =3.« less
X-ray crystal structure of divalent metal-activated ß-xyloisdase, RS223BX
USDA-ARS?s Scientific Manuscript database
We report the first X-ray structure of a glycoside hydrolase family 43 ß-xylosidase, RS223BX, which is strongly activated by the addition of divalent metal cations. The 2.69 Å structure reveals that the Ca2+ cation is located at the back of the active site pocket. The Ca2+ coordinates to H274 to sta...
Social vulnerabilities as determinants of overweight in 2-, 4- and 6-year-old Spanish children.
Iguacel, Isabel; Fernández-Alvira, Juan M; Labayen, Idoia; Moreno, Luis A; Samper, María Pilar; Rodríguez, Gerardo
2018-04-01
Differences in obesity prevalence among vulnerable groups exist in childhood but it remains unclear whether these differences may be partly determined by socioeconomic status (SES), parental body mass index (BMI) and early life risk factors. We aimed to explore (i) longitudinal associations between belonging to a minority group and being overweight/obese at age 2, 4 and 6 and (ii) associations between accumulation of social vulnerabilities and being overweight/obese at age 6. In total, 1031 children (53.8% boys) were evaluated at birth and re-examined during a 6-year follow-up in a representative cohort of Aragon (Spain). Children from minority (vulnerable) groups included Spanish Roma/gypsies, Eastern Europeans, Latin Americans and Africans. Two more vulnerable groups were defined at baseline as children whose parents reported low occupation and education. Ethnicity, SES and parental BMI were collected via interviews. We used logistic mixed-effects models and adjusted for parental BMI, SES, mother's tobacco use, maternal weight gain, birth weight, infant weight gain and breastfeeding practices. Regardless of confounders, Roma/gypsy children (OR = 4.63;[1.69-12.70]95%CI) and with Latin American background (OR = 3.04;[1.59-5.82]95%CI) were more likely to be overweight/obese at age 6 compared with non-gypsy Spanish group. Children with three vulnerabilities (OR = 2.18;[1.31-3.64]95%CI) were more likely to be overweight/obese at age 6 compared with children with no vulnerabilities. No associations were found between belonging to a minority group and overweight/obesity in children under 6. Interventions should target Roma/gypsy children, Latin American children and those who accumulate more vulnerabilities as they are at higher risk of being overweight/obese at age 6.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-27
... Codify Pricing for Co-Location Services October 21, 2010. Pursuant to Section 19(b)(1) of the Securities...-location services. BX will implement the proposed change immediately. The text of the proposed rule change... Recently, the Commission approved an initial fee schedule of existing fees for the Exchange's co-location...
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2010-11-02
... Modify Pricing for Co-Location Services October 27, 2010. Pursuant to Section 19(b)(1) of the Securities... co-location services. BX will implement the proposed change immediately. The text of the proposed... Exchange is proposing to modify its fee schedule \\5\\ for co- location services.\\6\\ These modifications are...
Shared Features of L2 Writing: Intergroup Homogeneity and Text Classification
ERIC Educational Resources Information Center
Crossley, Scott A.; McNamara, Danielle S.
2011-01-01
This study investigates intergroup homogeneity within high intermediate and advanced L2 writers of English from Czech, Finnish, German, and Spanish first language backgrounds. A variety of linguistic features related to lexical sophistication, syntactic complexity, and cohesion were used to compare texts written by L1 speakers of English to L2…
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2012-06-08
... Organizations; NASDAQ OMX BX; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Dissolve... dissolve the BOX Committee of the Board of Directors. The text of the proposed rule change is available at... Basis for, the Proposed Rule Change 1. Purpose The Exchange proposes to dissolve the BOX Committee of...
Santagati, Vito Davide; Sestili, Francesco; Lafiandra, Domenico; D'Ovidio, Renato; Rogniaux, Helene; Masci, Stefania
2016-07-01
Wheat high molecular weight glutenin subunit variation is important because of its great influence on glutenin polymer structure, that is related to dough technological properties. Among the different subunits, the pair Bx20 and By20 is known to have a negative effect on quality, but the reasons are not clear: Bx20 has two cysteines, which theoretically make this subunit a chain extender of the glutenin polymer, just like the other Bx subunits, showing four cysteines, two of which should be involved in intra-molecular disulfide bonds. By20 has never been characterized so far at molecular level. Here we report the nucleotide sequences of Bx20 and By20 genes isolated from the durum wheat cultivar 'Lira 45' and the validation of the corresponding deduced amino acid sequences by using MALDI-TOF and LC-MS/MS. Four nucleotide differences were identified in the Bx20 gene with respect to the deduced sequence present in NCBI, causing two amino acid substitutions. For the By20 subunit, nucleotide and amino acid sequences revealed a great similarity to By15, both at gene and protein levels, showing five nucleotide changes generating two amino acid differences. No evidence of post-translational modifications has been found. Hypotheses are formulated in regard to relationships with technological quality. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
Yang, Liheng; Gao, Zhenxing; Hu, Lipeng; Wu, Guiru; Yang, Xiaowen; Zhang, Lihua; Zhu, Ying; Wong, Boon-Seng; Xin, Wei; Sy, Man-Sun; Li, Chaoyang
2016-01-01
The normal cellular prion protein (PrP) is a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein. However, in pancreatic ductal adenocarcinoma cell lines, such as BxPC-3, PrP exists as a pro-PrP retaining its glycosylphosphatidylinositol (GPI) peptide signaling sequence. Here, we report the identification of another pancreatic ductal adenocarcinoma cell line, AsPC-1, which expresses a mature GPI-anchored PrP. Comparison of the 24 genes involved in the GPI anchor modification pathway between AsPC-1 and BxPC-3 revealed 15 of the 24 genes, including PGAP1 and PIG-F, were down-regulated in the latter cells. We also identified six missense mutations in DPM2, PIG-C, PIG-N, and PIG-P alongside eight silent mutations. When BxPC-3 cells were fused with Chinese hamster ovary (CHO) cells, which lack endogenous PrP, pro-PrP was successfully converted into mature GPI-anchored PrP. Expression of the individual gene, such as PGAP1, PIG-F, or PIG-C, into BxPC-3 cells does not result in phosphoinositide-specific phospholipase C sensitivity of PrP. However, when PIG-F but not PIG-P is expressed in PGAP1-expressing BxPC-3 cells, PrP on the surface of the cells becomes phosphoinositide-specific phospholipase C-sensitive. Thus, low expression of PIG-F and PGAP1 is the major factor contributing to the accumulation of pro-PrP. More importantly, BxPC-3 cells expressing GPI-anchored PrP migrate much slower than BxPC-3 cells bearing pro-PrP. In addition, GPI-anchored PrP-bearing AsPC-1 cells also migrate slower than pro-PrP bearing BxPC-3 cells, although both cells express filamin A. “Knocking out” PRNP in BxPC-3 cell drastically reduces its migration. Collectively, these results show that multiple gene irregularity in BxPC-3 cells is responsible for the formation of pro-PrP, and binding of pro-PrP to filamin A contributes to enhanced tumor cell motility. PMID:26683373
Interpretation of the Coefficients in the Fit y = at + bx + c
ERIC Educational Resources Information Center
Farnsworth, David L.
2006-01-01
The goals of this note are to derive formulas for the coefficients a and b in the least-squares regression plane y = at + bx + c for observations (t[subscript]i,x[subscript]i,y[subscript]i), i = 1, 2, ..., n, and to present meanings for the coefficients a and b. In this note, formulas for the coefficients a and b in the least-squares fit are…
Ding, Li-Ping; Shao, Peng; Lu, Cheng; Zhang, Fang-Hui; Ding, Lei; Yuan, Tao Li
2016-08-17
The structure and bonding nature of neutral and negatively charged BxAlyH2 (x + y = 7, 8, 9) clusters are investigated with the aid of previously published experimental photoelectron spectra combined with the present density functional theory calculations. The comparison between the experimental photoelectron spectra and theoretical simulated spectra helps to identify the ground state structures. The accuracy of the obtained ground state structures is further verified by calculating their adiabatic electron affinities and vertical detachment energies and comparing them against available experimental data. The results show that the structures of BxAlyH2 transform from three-dimensional to planar structures as the number of boron atoms increases. Moreover, boron atoms tend to bind together forming Bn units. The hydrogen atoms prefer to bind with boron atoms rather than aluminum atoms. The analyses of the molecular orbital on the ground state structures further support the abovementioned results.
Nambiar, Dhanya; Prajapati, Vandana; Agarwal, Rajesh; Singh, Rana P
2013-06-28
Silibinin suppresses the growth of many cancers; however, its efficacy against pancreatic cancer has not been evaluated in established preclinical models. Here, we investigated in vitro and in vivo effects of silibinin against lower and advanced stages of human pancreatic carcinoma cells. Silibinin (25-100μM) treatment for 24-72h caused a dose- and time-dependent cell growth inhibition of 27-77% (P<0.05-0.001) in BxPC-3 cells, and 22-45% (P<0.01-0.001) in PANC-1 cells. Silibinin showed a strong dose-dependent G1 arrest in BxPC-3 cells (upto 72% versus 45% in control; P<0.001), but a moderate response in advanced PANC-1 cells. Cell death observed in cell growth assay, was accompanied by up to 3-fold increase (P<0.001) in apoptosis in BxPC-3 cells, and showed only slight effect on PANC-1 cells. Dietary feeding of silibinin (0.5%, w/w in AIN-93M diet for 7weeks) inhibited BxPC-3 and PANC-1 tumor xenografts growth in nude mice without any apparent change in body weight gain and diet consumption. Tumor volume and weight were decreased by 47% and 34% (P⩽0.001) in BxPC-3 xenograft, respectively. PANC-1 xenograft showed slower growth kinetics and silibinin decreased tumor volume by 34% (P<0.001) by 7weeks. Another 4weeks of silibinin treatment to PANC-1 xenograft showed 28% and 33% decrease in tumor volume and weight, respectively. Silibinin-fed group of BxPC-3 tumors showed decreased cell proliferation and angiogenesis and an increased apoptosis, however, considerable inhibitory effect was observed only for angiogenesis in PANC-1 tumors. Overall, these findings show both in vitro as well as in vivo anticancer efficacy of silibinin against pancreatic cancer that could involve inhibition of cell proliferation, cell cycle arrest, apoptosis induction and/or decrease in tumor angiogenesis. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
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2012-05-04
... they deem fee levels at a particular venue to be excessive. In such an environment, BX must continually... excessive extent, it will lose customers to its competitors. Accordingly, BX believes that competitive market forces help to ensure that the fees it charges for execution and routing are reasonable, equitably...
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2013-10-31
... Directed Order to the list of orders handled within the BX System. \\13\\ Proposed BX Chapter VI, Section 10... impediments to and perfect the mechanism of a free and open market and a national market system, and to... mechanism of a free and open market and the national market system, or protect investors and the public...
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2010-09-16
... Stock Exchange, Inc.; EDGA Exchange, Inc.; EDGX Exchange, Inc.; International Securities Exchange LLC; The NASDAQ Stock Market LLC; National Stock Exchange, Inc.; New York Stock Exchange LLC; NYSE Amex LLC...''), NASDAQ OMX BX, Inc. (``BX''), Chicago Board Options Exchange, Incorporated (``CBOE''), Chicago Stock...
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2013-02-12
... posting Protected Quotations within the meaning of Regulation NMS (i.e. ``dark venues'' or ``dark pools... seek to execute on BX or on dark pools without executing on another exchange. Members may seek to....00- $10.01, and BX, DarkVenueA and ARCA each offer 100 shares at $10.01, a BDRK order to buy 1000...
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2012-12-14
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-68394; File No. SR-BX-2012-073] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change With Respect to the Authority of the Exchange or Nasdaq Options Services LLC (``NOS'') To Cancel Options Orders When a Technical or System Issu...
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2010-01-14
... addresses BX Rule 2240 entitled ``Disclosure of Control Relationship with Issuer'' and 2250 entitled... reference to NASD 2240 [sic] entitled ``Disclosure of Control Relationship with Issuer.'' The Commission... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-61298; File No. SR-BX-2009-087] Self-Regulatory...
Vasylkiv, Oleg; Borodianska, Hanna; Badica, Petre; Grasso, Salvatore; Sakka, Yoshio; Tok, Alfred; Su, Liap Tat; Bosman, Michael; Ma, Jan
2012-02-01
Boron carbide B4C powders were subject to reactive spark plasma sintering (also known as field assisted sintering, pulsed current sintering or plasma assisted sintering) under nitrogen atmosphere. For an optimum hexagonal BN (h-BN) content estimated from X-ray diffraction measurements at approximately 0.4 wt%, the as-prepared BaCb-(BxOy/BN) ceramic shows values of Berkovich and Vickers hardness of 56.7 +/- 3.1 GPa and 39.3 +/- 7.6 GPa, respectively. These values are higher than for the vacuum SPS processed B4C pristine sample and the h-BN -mechanically-added samples. XRD and electronic microscopy data suggest that in the samples produced by reactive SPS in N2 atmosphere, and containing an estimated amount of 0.3-1.5% h-BN, the crystallite size of the boron carbide grains is decreasing with the increasing amount of N2, while for the newly formed lamellar h-BN the crystallite size is almost constant (approximately 30-50 nm). BN is located at the grain boundaries between the boron carbide grains and it is wrapped and intercalated by a thin layer of boron oxide. BxOy/BN forms a fine and continuous 3D mesh-like structure that is a possible reason for good mechanical properties.
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2011-11-23
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-65780; File No. SR-BX-2011-076] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Perform a Test of Routing Functionality November 17, 2011. Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934 (``Act''),\\1\\...
ERIC Educational Resources Information Center
Thompson, Mary P.; And Others
This is the third volume in a series of texts in a conversational Spanish course for elementary school children. Nine basic units present introductory linguistic patterns and cultural insights into the lives of the Spanish people. They include: (1) Review Unit 1, ("Cristobal Colon"), (2) Review Unit 2, (3) "Un Accidente,""La Navidad," and…
Navarro Suay, Ricardo; Tamburri Bariain, Rafael; Gutiérrez Ortega, Carlos; Hernández Abadía de Barbará, Alberto; López Soberón, Edurne; Rodríguez Moro, Carlos
2014-01-01
Since 1987, the Spanish Armed Forces have deployed their troops in a multitude of conflicts and natural disasters worldwide. The Spanish Military Medical Corps has the ability to deploy Role 1, Role 2, and one Role 3 medical treatment facilities. It also has a Role 4 in operation, the "Gómez Ulla" Central Hospital of Defense, in Madrid. The aim of this study is to describe the type of Spanish casualties evacuated from different areas of operation to the Role 4 from 2008 to 2013. A retrospective, cross-sectional study was performed on a sample of 232 patients. Among these, 211 (91%) were noncombat casualties: 126 because of illness, 53 because of an accident, and 32 because of sports injuries. The remaining 21 (9%) were combat casualties: 11 from improvised explosive devices and 10 from gunfire. Afghanistan, followed by Lebanon, is the operational area where most evacuees originate. The authors consider it essential that the Spanish Armed Forces rely on a Role 4 medical treatment facility as part of their medical support to international operations. Reprint & Copyright © 2014 Association of Military Surgeons of the U.S.
Thuesen, Leif; Galløe, Anders; Thayssen, Per; Rasmussen, Klaus; Kelbæk, Henning; Lassen, Jens Flensted; Hansen, Peter Riis; Pedersen, Knud Erik; Ravkilde, Jan; Helquist, Steffen; Abildgaard, Ulrik; Andersen, Henning Rud; Bøtker, Hans Erik; Kristensen, Steen Dalby; Hjort, Jacob; Krusell, Lars Romer
2005-11-01
To compare deliverability and in-hospital complications in implantation of BxSonic(R), Express(R), and Flexmaster(R) coronary stents in a randomized multicenter trial in five Danish interventional centres. Patients with planned stenting of at least one stenotic lesion in a native coronary artery were included in the study. There were 494 (664) patients (treated lesions) in the BxSonic(R), 499 (657) in the Express(R) and 500 (658) in the Flexmaster(R) groups. The groups were well matched with regard to age, sex, diabetes, smoking, hypercholesterolemia, hypertension, indication for PCI and coronary artery lesion complexity. The study stents were implanted with or without predilatation according to ordinary -clinical practice.Rates of successful stent implantation and in-hospital stent thrombosis, re-intervention, non-fatal myocardial infarction or death. The BxSonic(R), Express(R) and Flexmaster(R) stents were successfully implanted in 92,2%, 89,3% and 91,6% of all lesions (ns). There were no in-hospital deaths and the rates of in-hospital complications were similar in the three stent groups. We found similar deliverability and in-hospital complication rates of the BxSonic(R), Express(R) and Flexmaster(R) stents.
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2012-02-28
...-BX-2011-073). \\4\\ Id. at 80998. The Exchange now proposes a pass-through reduction in the fees for.... The Exchange is passing along the entire savings of the reduction in fees to the subscribers of the... passing on reduced costs to members that opt to receive the connectivity options in question. \\8\\ See...
Navas, Paula; Tenorio, Jair; Quezada, Carlos Andrés; Barrios, Elvira; Gordo, Gema; Arias, Pedro; López Meseguer, Manuel; Santos-Lozano, Alejandro; Palomino Doza, Julian; Lapunzina, Pablo; Escribano Subías, Pilar
2016-11-01
Recent advances in genetics have led to the discovery of new genes associated with pulmonary arterial hypertension, such as TBX4 and KCNK3. The phenotype and prognosis associated with these new genes have been scarcely described and their role in the Spanish population is unknown. The aim of this study was to characterize the genetics of a Spanish cohort of patients with idiopathic and hereditary pulmonary arterial hypertension and to describe the phenotype and prognostic factors associated with BMPR2 and the new genes (KCNK3 and TBX4). A total of 165 adult patients were screened for BMPR2, KCNK3, and TBX4 mutations, 143 with idiopathic pulmonary arterial hypertension and 22 with hereditary pulmonary arterial hypertension. Baseline characteristics and survival were compared among the different subgroups and predictors of poor outcomes were analyzed. We also performed family screening. The genetic study identified a possibly associated mutation in 11.10% of the idiopathic cases (n = 16) and in 68.18% of the hereditary cases (n = 15). There were 19 mutations in BMPR2, 4 in TBX4, and 3 in KCNK3. The forms associated with TBX4 showed the highest survival rate (P < .01). Advanced functional class at diagnosis was the only factor associated with poor outcomes in the hereditary forms. In the family screening, 37.5% of relatives tested positive. The genetics of pulmonary arterial hypertension in the Spanish population may differ from other populations, with a lower proportion of BMPR2 causative mutations. In our cohort, TBX4-related forms of pulmonary arterial hypertension showed a more benign course and late diagnosis was the only predictor of adverse outcomes in the hereditary forms of the disease. Copyright © 2016 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.
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2010-12-15
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-63499; File No. SR-BX-2010-087] Self-Regulatory... Quote Management Procedures December 9, 2010. Pursuant to Section 19(b)(1) of the Securities Exchange...-4(f)(6). I. Self-Regulatory Organization's Statement of the Terms of Substance of the Proposed Rule...
Shewry, P R; Gilbert, S M; Savage, A W J; Tatham, A S; Wan, Y-F; Belton, P S; Wellner, N; D'Ovidio, R; Békés, F; Halford, N G
2003-02-01
The gene encoding high-molecular-weight (HMW) subunit 1Bx20 was isolated from durum wheat cv. Lira. It encodes a mature protein of 774 amino acid residues with an M(r) of 83,913. Comparison with the sequence of subunit 1Bx7 showed over 96% identity, the main difference being the substitution of two cysteine residues in the N-terminal domain of subunit 1Bx7 with tyrosine residues in 1Bx20. Comparison of the structures and stabilities of the two subunits purified from wheat using Fourier-transform infra-red and circular dichroism spectroscopy showed no significant differences. However, incorporation of subunit 1Bx7 into a base flour gave increased dough strength and stability measured by Mixograph analysis, while incorporation of subunit 1Bx20 resulted in small positive or negative effects on the parameters measured. It is concluded that the different effects of the two subunits could relate to the differences in their cysteine contents, thereby affecting the cross-linking and hence properties of the glutenin polymers.
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2011-05-18
... addresses BX Rule 3011 pertaining to anti-money laundering compliance programs. In SR-FINRA-2009-039,\\3... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To... received. III. Date of Effectiveness of the Proposed Rule Change and Timing for Commission Action Because...
Basso, Daniela; Gnatta, Elisa; Padoan, Andrea; Fogar, Paola; Furlanello, Sara; Aita, Ada; Bozzato, Dania; Zambon, Carlo-Federico; Arrigoni, Giorgio; Frasson, Chiara; Franchin, Cinzia; Moz, Stefania; Brefort, Thomas; Laufer, Thomas; Navaglia, Filippo; Pedrazzoli, Sergio; Basso, Giuseppe; Plebani, Mario
2017-10-17
Tumor genetics and escape from immune surveillance concur in the poor prognosis of PDAC. In this study an experimental model was set up to verify whether SMAD4 , deleted in about 55% PDAC and associated with poor prognosis, is involved in determining immunosuppression through Exosomes (Exo). Potential mechanisms and mediators underlying SMAD4 -dependent immunosuppression were evaluated by studying intracellular calcium (Fluo-4), Exo-miRNAs (microarray) and Exo-proteins (SILAC). Two PDAC cell lines expressing (BxPC3- SMAD4 +) or not-expressing (BxPC3) SMAD4 were used to prepare Exo-enriched conditioned media, employed in experiments with blood donors PBMCs. Exo expanded myeloid derived suppressor cells (gMDSC and mMDSC, flow cytometry) and altered intracellular calcium fluxes in an SMAD4 dependent manner. BxPC3- SMAD4 +, but mainly BxPC3 Exo, increased calcium fluxes of PBMCs ( p = 0.007) and this increased intracellular calcium trafficking characterized mMDSCs. The analysis of de-regulated Exo-miRNAs and transfection experiments revealed hsa-miR-494-3p and has-miR-1260a as potential mediators of SMAD4- associated de-regulated calcium fluxes. Eleven main biological processes were identified by the analysis of SMAD4 -associated de-regulated Exo-proteins, including translation, cell adhesion, cell signaling and glycolysis. A reverse Warburg effect was observed by treating PBMCs with PDAC-derived Exo: BxPC3 Exo induced a higher glucose consumption and lactate production than BxPC3- SMAD4 + Exo. PDAC-derived Exo from cells with , but mainly from those without SMAD4 expression, create an immunosuppressive myeloid cell background by increasing calcium fluxes and glycolysis through the transfer of SMAD4 -related differentially expressed miRNAs and proteins.
Basso, Daniela; Gnatta, Elisa; Padoan, Andrea; Fogar, Paola; Furlanello, Sara; Aita, Ada; Bozzato, Dania; Zambon, Carlo-Federico; Arrigoni, Giorgio; Frasson, Chiara; Franchin, Cinzia; Moz, Stefania; Brefort, Thomas; Laufer, Thomas; Navaglia, Filippo; Pedrazzoli, Sergio; Basso, Giuseppe; Plebani, Mario
2017-01-01
Tumor genetics and escape from immune surveillance concur in the poor prognosis of PDAC. In this study an experimental model was set up to verify whether SMAD4, deleted in about 55% PDAC and associated with poor prognosis, is involved in determining immunosuppression through Exosomes (Exo). Potential mechanisms and mediators underlying SMAD4-dependent immunosuppression were evaluated by studying intracellular calcium (Fluo-4), Exo-miRNAs (microarray) and Exo-proteins (SILAC). Two PDAC cell lines expressing (BxPC3-SMAD4+) or not-expressing (BxPC3) SMAD4 were used to prepare Exo-enriched conditioned media, employed in experiments with blood donors PBMCs. Exo expanded myeloid derived suppressor cells (gMDSC and mMDSC, flow cytometry) and altered intracellular calcium fluxes in an SMAD4 dependent manner. BxPC3-SMAD4+, but mainly BxPC3 Exo, increased calcium fluxes of PBMCs (p = 0.007) and this increased intracellular calcium trafficking characterized mMDSCs. The analysis of de-regulated Exo-miRNAs and transfection experiments revealed hsa-miR-494-3p and has-miR-1260a as potential mediators of SMAD4-associated de-regulated calcium fluxes. Eleven main biological processes were identified by the analysis of SMAD4-associated de-regulated Exo-proteins, including translation, cell adhesion, cell signaling and glycolysis. A reverse Warburg effect was observed by treating PBMCs with PDAC-derived Exo: BxPC3 Exo induced a higher glucose consumption and lactate production than BxPC3-SMAD4+ Exo. Conclusion: PDAC-derived Exo from cells with, but mainly from those without SMAD4 expression, create an immunosuppressive myeloid cell background by increasing calcium fluxes and glycolysis through the transfer of SMAD4-related differentially expressed miRNAs and proteins. PMID:29156694
Largani, Tahere Hosseyni; Imanzadeh, Gholamhasan; Pesyan, Nader Noroozi; Şahin, Ertan; Shamkhali, Amir Nasser; Notash, Behrouz
2018-02-01
The regioselective syntheses of novel pyrazolo[1[Formula: see text],5[Formula: see text]:1,2]pyrrolo[3,4-b]quinoline-2,3-dicarboxylates (6a-l) from pyrrolo([3,4-b]quinolin-2(3H)-yl)benzamides through an intramolecular Wittig reaction are described. This protocol takes advantages of mild conditions, simple workup and high yield which make this method attractive for the synthesis of these hybrid of pyrazolo[1[Formula: see text],5[Formula: see text]:1,2]pyrrolo[3,4-b]quinolines.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-18
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-63694; File No. SR-BX-2011-001] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Amend the BOX Trading Rules Regarding Voluntary Withdrawal From Trading Options Classes in Which They Are Appointed January 11, 2011....
Relations Between vz and Bx Components in Solar Wind and their Effect on Substorm Onset
NASA Astrophysics Data System (ADS)
Kubyshkina, Marina; Semenov, Vladimir; Erkaev, Nikolay; Gordeev, Evgeny; Dubyagin, Stepan; Ganushkina, Natalia; Shukhtina, Maria
2018-05-01
We analyze two substorm onset lists, produced by different methods, and show that the (Bx·vz) product of the solar wind (SW) velocity and interplanetary magnetic field (IMF) components for two thirds of all substorm onsets has the same sign as IMF Bz. The explanation we suggest is the efficient displacement of the magnetospheric plasma sheet due to IMF Bx and SW flow vz, which both force the plasma sheet moving in one direction if the sign of (Bx·vz) correlates with the sign Bz. The displacement of the current sheet, in its turn, increases the asymmetry of the magnetotail and can alter the threshold of substorm instabilities. We study the SW and IMF data for the 15-year period (which comprises two substorm lists periods and the whole solar cycle) and reveal the similar asymmetry in the SW, so that the sign of (Bx·vz) coincides with the sign of IMF Bz during about two thirds of all the time. This disproportion can be explained if we admit that about 66% of IMF Bz component is transported to the Earth's orbit by the Alfvén waves with antisunward velocities.
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2010-01-08
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-61261; File No. SR-BX-2009-086] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change Relating to the Minimum Trading Increments on the Boston Options Exchange Facility December 30, 2009. Pursuant to Section 19(b)(1) of the...
L1 English/L2 Spanish: Orthography-Phonology Activation without Contrasts
ERIC Educational Resources Information Center
Shea, Christine
2017-01-01
We consider how orthography activates sounds that are in a noncontrastive relationship in the second language (L2) and for which only one variant exists in the first language (L1). Participants were L1 English / L2 Spanish and native Spanish listeners. Intervocalically, Spanish graphemes "b d g" correspond phonetically to stops and…
Chatting in L2 Spanish: Interactivity, Self-Efficacy and Interpersonal Relations
ERIC Educational Resources Information Center
Sanchez-Castro, Olga; Mrowa-Hopkins, Colette
2012-01-01
This study seeks to examine variations in patterns of interactivity as they are displayed in the ongoing discourse construction of high and low self-efficacy learners of Spanish in the context of computer-mediated-communication. The paper specifically focuses on the analysis of synchronous text chats of six university students of Spanish at…
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2010-12-29
....\\4\\ The Commission subsequently extended the time period in which to either approve the proposed rule... Market.'' The BX Venture Market will have minimal quantitative listing standards, but have qualitative... securities exchange for failure to meet quantitative listing standards (including price or other market value...
Development and preliminary evaluation of a pediatric Spanish-English speech perception task.
Calandruccio, Lauren; Gomez, Bianca; Buss, Emily; Leibold, Lori J
2014-06-01
The purpose of this study was to develop a task to evaluate children's English and Spanish speech perception abilities in either noise or competing speech maskers. Eight bilingual Spanish-English and 8 age-matched monolingual English children (ages 4.9-16.4 years) were tested. A forced-choice, picture-pointing paradigm was selected for adaptively estimating masked speech reception thresholds. Speech stimuli were spoken by simultaneous bilingual Spanish-English talkers. The target stimuli were 30 disyllabic English and Spanish words, familiar to 5-year-olds and easily illustrated. Competing stimuli included either 2-talker English or 2-talker Spanish speech (corresponding to target language) and spectrally matched noise. For both groups of children, regardless of test language, performance was significantly worse for the 2-talker than for the noise masker condition. No difference in performance was found between bilingual and monolingual children. Bilingual children performed significantly better in English than in Spanish in competing speech. For all listening conditions, performance improved with increasing age. Results indicated that the stimuli and task were appropriate for speech recognition testing in both languages, providing a more conventional measure of speech-in-noise perception as well as a measure of complex listening. Further research is needed to determine performance for Spanish-dominant listeners and to evaluate the feasibility of implementation into routine clinical use.
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2010-12-08
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-63416; File No. SR-BX-2010-083] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change Relating to The Price Improvement... Items I and II below, which Items have been prepared by the self-regulatory organization. The Commission...
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2013-06-10
..., Section 6(a)(2) to include Directed Order to the list of orders handled within the BX System. \\9\\ Chapter... rule change, by rewarding market makers whose quotes are not the most aggressive, will encourage market... rewarded for providing an aggressive quote and thus the incentives to improve the NBBO would decrease...
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2012-05-23
... current Grandfathered Rules, Chapter XXX, Section 2(a). See also BX Rule 9211. A disciplinary proceeding... Consent. See Chapter XXX, Section 10 and Chapter XXXIV. \\9\\ Compare to American Stock Exchange (``AMEX... Floor Decorum Policies) of Chapter XVIII (Conduct) is being amended to reflect that Chapter XXX is being...
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2012-05-23
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-67014; File No. SR-BX-2012-034] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change With Respect to the Authority of the Exchange or NASDAQ Execution Services to Cancel Orders When a Technical or System Issue Occurs and To Describe the Operation of an...
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2013-05-10
... priority of the order on the book solely for the purpose of modifying the marking of a sell order as long... its share size will not affect the priority of the order on the book. All other modifications of... order to lose priority on the BX book. BX believes that it is reasonable to allow the partial...
Butow, B J; Gale, K R; Ikea, J; Juhász, A; Bedö, Z; Tamás, L; Gianibelli, M C
2004-11-01
Increased expression of the high molecular weight glutenin subunit (HMW-GS) Bx7 is associated with improved dough strength of wheat (Triticum aestivum L.) flour. Several cultivars and landraces of widely different genetic backgrounds from around the world have now been found to contain this so-called 'over-expressing' allelic form of the Bx7 subunit encoded by Glu-B1al. Using three methods of identification, SDS-PAGE, RP-HPLC and PCR marker analysis, as well as pedigree information, we have traced the distribution and source of this allele from a Uruguayan landrace, Americano 44D, in the mid-nineteenth century. Results are supported by knowledge of the movement of wheat lines with migrants. All cultivars possessing the Glu-B1al allele can be identified by the following attributes: (1) the elution of the By sub-unit peak before the Dx sub-unit peak by RP-HPLC, (2) high expression levels of Bx7 (>39% Mol% Bx), (3) a 43 bp insertion in the matrix-attachment region (MAR) upstream of the gene promoter relative to Bx7 and an 18 bp nucleotide duplication in the coding region of the gene. Evidence is presented indicating that these 18 and 43 bp sequence insertions are not causal for the high expression levels of Bx7 as they were also found to be present in a small number of hexaploid species, including Chinese Spring, and species expressing Glu-B1ak and Glu-B1a alleles. In addition, these sequence inserts were found in different isolates of the tetraploid wheat, T. turgidum, indicating that these insertion/deletion events occurred prior to hexaploidization.
Digital Stories: Bringing Multimodal Texts to the Spanish Writing Classroom
ERIC Educational Resources Information Center
Oskoz, Ana; Elola, Idoia
2016-01-01
Despite the availability and growing use of digital story software for authoring and instructional purposes, little is known about learners' perceptions on its integration in the foreign language writing class. Following both a social semiotics approach and activity theory, this study focuses on six advanced Spanish learners' perceptions about the…
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2013-05-21
... To Permit BX Options To Accept Inbound Options Orders From NASDAQ OMX PHLX LLC and NASDAQ Options... to permit the BX Options System to accept inbound options orders routed by Nasdaq Options Services LLC (``NOS'') from NASDAQ OMX PHLX LLC (``Phlx'') and The NASDAQ Stock Market LLC's NASDAQ Options...
Secondary School Languages: Spanish.
ERIC Educational Resources Information Center
British Columbia Dept. of Education, Victoria.
This curriculum guide outlines three programs for secondary school Spanish instruction, each program covering grades 9, 10, and 11 in British Columbian schools. Each outline specifies basic texts, supplementary readings, and teaching aids. In addition, a very basic outline of a beginner's Spanish 11 is offered, and a Spanish 12 literature course…
Photometric study of the W UMa eclipsing binaries VW LMi and BX Dra
NASA Astrophysics Data System (ADS)
Sánchez-Bajo, F.; García-Melendo, E.; Gómez-Forrellad, J. M.
2007-12-01
New ephemeris and the absolute parameters—masses, radii and luminosities—of the contact systems VW LMi and BX Dra have been obtained, by means of the analysis of the minima data available in the literature (for the determination of the ephemeris) and combining the previously published spectroscopic information and the results of the Wilson-Devinney method using photometric data (for the determination of the absolute parameters). The VW LMi O- C analysis confirms the multiplicity of the system detected previously from the spectroscopic data. Masses of the VW LMi contact system primary and secondary components are 1.67 ± 0.02 M ⊙ and 0.70 ± 0.02 M ⊙, respectively. The corresponding radii are 1.709 ± 0.007 R ⊙ and 1.208 ± 0.006 R ⊙, respectively. For the BX Dra contact system the masses are 2.19 ± 0.13 M ⊙ and 0.63 ± 0.06 M ⊙, and the radii, 2.13 ± 0.04 R ⊙ and 1.26 ± 0.03 R ⊙, for the primary and secondary, respectively. In both cases, the estimated luminosities seem to be slightly greater that the values derived from the Hipparcos distances.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-02
... with a time-in- force designation of Good Til canceled (``GTC'') are treated as having a time-in-force... designation of Good Til Cancelled or Immediate or Cancel. See proposed BX Options Rules, Chapter VI, Section 1...
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2013-10-22
... review functions focused on: (1) Manipulation patterns that monitor solely BX activity, including patterns that monitor the opening and closing crosses on The NASDAQ Stock Market LLC (``NASDAQ'') and...
The Acquisition of Questions in Texas Spanish: Age 2 - Age 5.
ERIC Educational Resources Information Center
Gonzalez, Gustavo
To determine the normal sequence of the development of Spanish phonology and Spanish grammatical patterns in the speech of native Spanish speakers, ages 2-5, a study of the acquisition of interrogative formation was undertaken. Two male and two females from each of nine age intervals between two and five were selected as informants; all were…
[Inactivity, obesity and mental health in the Spanish population from 4 to 15 years of age].
Rodríguez-Hernández, Arturo; Cruz-Sánchez, Ernesto de la; Feu, Sebastián; Martínez-Santos, Raúl
2011-08-01
An active lifestyle and a good weight status are two major health determinants from a public health perspective. To evaluate the degree of association between physical activity, weight status and the emotional and mental health of Spanish schoolchildren. Mental health status was assessed through the Strengths and Difficulties Questionnaire (SDQ), also leisure time physical activity and body mass index (BMI) in a total of 6 803 children from 4 to 15 years participating in the Spanish National Health Survey 2006. The degree of association between. these variables was estimated by a multinomial logistic regression analysis. Among sedentary schoolchildren are more common mental health problems (OR 2.10), emotional problems (OR 1.84), conduct problems (OR 1.53), problems with peers (OR 2.35) and social relationship difficulties (OR 1.36). Obesity is associated with poor general mental health (OR 1.58), and obese schoolchildren show more often emotional problems (OR 1.52) and problems with peers (OR 2.43). In the Spanish schoolchildren, a healthy BMI is associated with increased mental well-being, although an active lifestyle is the best indicator of a good mental health status.
Torabi, F; Bogle, O A; Estanyol, J M; Oliva, R; Miller, D
2017-12-01
Are there novel hyaladherins in human sperm? Zona pellucida-binding protein 2 (ZPBP2), containing a Link-like hyaluronic acid (HA)-binding domain, and several other proteins containing BX7B motifs, such as ADAM32 and Midkine, may be novel hyaladherins with HA-binding properties. HA-binding proteins (hyaladherins), which can bind HA surrounding the cumulus-oophorus complex, are distinct from hyases such as PH 20 (SPAM1) and are expressed by mature spermatozoa. Although HABP1 and CD44 are reasonably well characterized hyaladherins and the former has been implicated in sperm-oocyte interactions, the overall significance of sperm hyaladherins for male fertility is still poorly understood. This was a laboratory-based investigation into human sperm hyaladherins undertaken as part of a three year PhD programme sponsored by the EU Marie Curie Training network, Reprotrain. Protein homogenates of sperm obtained from young men of unknown fertility (N = 4) were partitioned into HA-binding and non-binding fractions by a protein affinity 'panning' method; their subsequent characterization was by liquid chromatography-tandem mass spectrometry (LC-MS-MS) and partitioning behaviour was confirmed by western blotting. Sequences of proteins from both fractions were submitted to PDBsum to look for orthologous entries (PDB codes) and all returned codes were queried against the matching protein using SAS (Sequences Annotated by Structure) looking for structural similarities between them. A systematic search for other common features of hyaladherins was also undertaken. The presence of BX7B sequence motifs found in several well-described hyaladherins including RHAMM was used to assess efficacy of potential hyaladherin partitioning by the HA substrate. The data showed that 50% (14/28) and 34.5% (28/81) of proteins in the bound and unbound fractions, respectively, contained these motifs (one-tailed Z-score = 1.45; P = 0.074), indicating weak discrimination by the substrate. Querying PDBsum
Espanol avanzado para estudiantes de literatura (Advanced Spanish for Literature Students)
ERIC Educational Resources Information Center
Steel, Brian
1974-01-01
Spanish foreign language teaching should aim at the following: 1) adequate reading-comprehension ability; 2) fluency in spoken and written Spanish; and 3) ability to recognize linguistic characteristics in literature, which would serve as a basis for further graduate stylistic research. (Text is in Spanish.) (Author/DS)
Chicago's Spanish-Speaking Population: Selected Statistics.
ERIC Educational Resources Information Center
Chicago Dept. of Development and Planning, IL.
Based on selected data from the 1970 census, this report provides a general description of Chicago's Spanish-speaking population's: (1) general population characteristics; (2) age and family characteristics; (3) income; (4) labor force characteristics; (5) education; and (6) housing. Using the Census Bureau's definition of Spanish speaking (all…
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2011-11-22
... prefer not to advertise their order but are willing to provide price improvement. 2. Statutory Basis The... interest of investors because it will expedite the introduction of new features to the BX equities market... their introduction at the Exchange. Therefore, the Commission designates the proposal to be operative...
SCDC Spanish Curricula Units. Spanish SL, Unit 6, Grade 2, Teacher's Guide.
ERIC Educational Resources Information Center
Spanish Curricula Development Center, Miami Beach, FL.
Spanish for second graders is explored in the instructional and assessment activities of the unit six Spanish as a Second Language strand. The function of the strand is to help provide the English-dominant child with the structures and vocabulary needed for effective communication in a bilingual environment. Focus, objective, and materials for…
Kong, Su Chii; Nøhr-Nielsen, Asbjørn; Zeeberg, Katrine; Reshkin, Stephan Joel; Hoffmann, Else Kay; Novak, Ivana; Pedersen, Stine Falsig
2016-08-01
Novel treatments for pancreatic ductal adenocarcinoma (PDAC) are severely needed. The aim of this work was to explore the roles of H-lactate monocarboxylate transporters 1 and 4 (MCT1 and MCT4) in PDAC cell migration and invasiveness. Monocarboxylate transporter expression, localization, activity, and function were explored in human PDAC cells (MIAPaCa-2, Panc-1, BxPC-3, AsPC-1) and normal human pancreatic ductal epithelial (HPDE) cells, by quantitative polymerase chain reaction, immunoblotting, immunocytochemistry, lactate flux, migration, and invasion assays. MCT1 and MCT4 (messenger RNA, protein) were robustly expressed in all PDAC lines, localizing to the plasma membrane. Lactate influx capacity was highest in AsPC-1 cells and lowest in HPDE cells and was inhibited by the MCT inhibitor α-cyano-4-hydroxycinnamate (4-CIN), MCT1/MCT2 inhibitor AR-C155858, or knockdown of MCT1 or MCT4. PDAC cell migration was largely unaffected by MCT1/MCT2 inhibition or MCT1 knockdown but was reduced by 4-CIN and by MCT4 knockdown (BxPC-3). Invasion measured in Boyden chamber (BxPC-3, Panc-1) and spheroid outgrowth (BxPC-3) assays was attenuated by 4-CIN and AR-C155858 and by MCT1 or MCT4 knockdown. Human PDAC cells exhibit robust MCT1 and MCT4 expression and partially MCT1- and MCT4-dependent lactate flux. PDAC cell migration is partially dependent on MCT4; and invasion, on MCT1 and MCT4. Inhibition of MCT1 and MCT4 may have clinical relevance in PDAC.
Eventive and Stative Passives in Spanish L2 Acquisition: A Matter of Aspect
ERIC Educational Resources Information Center
De Garavito, Joyce Bruhn; Valenzuela, Elena
2008-01-01
This paper reports on an empirical study that examined knowledge of eventive and stative passives in the L2 Spanish grammar of L1 speakers of English. Although the two types of passive exist in English, the difference between them is not signaled in any specific way. In Spanish, in contrast, the distinction is marked by the choice of copula: "ser"…
The Light and Period Variations of the Eclipsing Binary BX Draconis
NASA Astrophysics Data System (ADS)
Park, Jang-Ho; Lee, Jae Woo; Kim, Seung-Lee; Lee, Chung-Uk; Jeon, Young-Beom
2013-02-01
New CCD photometric observations of BX Dra were carried out on 26 nights during the period from 2009 April to 2010 June. The long-term photometric behaviors of the system are obtained from detailed studies of the period and light variations, based on historical data and our new observations. All available light curves display total eclipses at secondary minima and inverse O'Connell effects with Max I fainter than Max II, which were satisfactorily modeled by adding a slightly time-varying hot spot on the primary star. A total of 87 times of minimum lights spanning over ˜74 yr, including our 22 timing measurements, were used for ephemeris computations. A detailed analysis of the O - C diagram disclosed that the orbital period shows an upward parabola in combination with a sinusoidal variation. The continuous increase of period at a rate of +5.65 × 10-7 d yr-1 is consistent with that calculated from the Wilson-Devinney synthesis code. It can be interpreted as a mass transfer from the secondary star to the primary at a rate of 2.74 × 10-7 M⊙ yr-1, which is one of the largest rates between components of the contact system. The most likely explanation of the sinusoidal variation having a period of 30.2 yr and a semiamplitude of 0.0062 d is a light-travel-time effect due to the existence of a circumbinary object. We suggest that BX Dra is probably a triple system, consisting of a primary star with a spectral type of F0, its secondary component of spectral type F1-2, and an unseen circumbinary object with a minimum mass of M3 = 0.23 M⊙.
Cultural Understanding: Spanish Level 1.
ERIC Educational Resources Information Center
Scott, Reid
The teacher's attention is focused on selected elements of Spanish culture which may be taught integrally with instructional materials found in the first-year Spanish texts "Entender y Hablar", "La Familia Fernandez", and "A-LM Spanish, Level One". Items are cross-referenced for 42 cultural concepts ranging from nicknames to streets, roads, and…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-13
...-Regulatory Organizations; NASDAQ OMX BX; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change To Identify the Proprietary Data Feed of BOX Market Information That BOX Makes Available to Its...). I. Self-Regulatory Organization's Statement of the Terms of Substance of the Proposed Rule Change...
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2011-12-27
... Latency Network Connections December 20, 2011. I. Introduction On October 31, 2011, NASDAQ OMX BX, Inc... establish a program for offering low latency network connections and to establish the initial fees for such connections. The Exchange also proposed administrative modifications to Exchange Rule 7034. The proposed rule...
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2011-08-05
...-Regulatory Organization's Statement on Comments on the Proposed Rule Change Received From Members... Organizations; NASDAQ OMX BX; Notice of Filing and Immediate Effectiveness of a Proposal to Amend Chapter VI... Exchange Commission (the ``Commission'') the proposed rule change as described in Items I and II below...
NASA Technical Reports Server (NTRS)
Fatoohi, Rod; Saini, Subbash; Ciotti, Robert
2006-01-01
We study the performance of inter-process communication on four high-speed multiprocessor systems using a set of communication benchmarks. The goal is to identify certain limiting factors and bottlenecks with the interconnect of these systems as well as to compare these interconnects. We measured network bandwidth using different number of communicating processors and communication patterns, such as point-to-point communication, collective communication, and dense communication patterns. The four platforms are: a 512-processor SGI Altix 3700 BX2 shared-memory machine with 3.2 GB/s links; a 64-processor (single-streaming) Cray XI shared-memory machine with 32 1.6 GB/s links; a 128-processor Cray Opteron cluster using a Myrinet network; and a 1280-node Dell PowerEdge cluster with an InfiniBand network. Our, results show the impact of the network bandwidth and topology on the overall performance of each interconnect.
FCAPT uvby Photometry of the mCP Stars HR 1297, 25 Sex, BX Boo, and 49 Her
NASA Astrophysics Data System (ADS)
Adelman, Saul J.
2008-06-01
I obtained additional differential Strömgren uvby observations of four magnetic CP stars HR 1297, 25 Sex, BX Boo, and 49 Her with the Four College Automated Photoelectric Telescope (FCAPT). The seasonal light curves of 25 Sex do not show definite differences. The period of Manfroid & Renson of 4.37900 days is confirmed. The other three stars usually have light curves in phase or nearly so, but there are differences between observing seasons. As the local properties of the photosphere change very slowly with time for these stars that have radiative atmospheres and strong magnetic fields, we are viewing slightly different hemispheres at the same phase. To produce this result, their rotational axes precess about their magnetic axes. For HR 1297, which has moderate amplitudes of variation, the period of Adelman is refined to 15.7505 days. The additional observations of BX Boo do not change the best estimate of its period, 2.88756 days. Although its amplitudes of variation are less than those of HR 1297, there are similar differences between observing seasons. For 49 Her the period of 0.93663 days of Adelman et al. is verified. There are probably small season-to-season light curve differences. Of the mCP stars for which I have FCAPT Strömgren observations, at least 13% exhibit variability among their light curves for different years.
A Spanish language and culture initiative for a doctor of pharmacy curriculum.
VanTyle, W Kent; Kennedy, Gala; Vance, Michael A; Hancock, Bruce
2011-02-10
To implement a Spanish language and culture initiative in a doctor of pharmacy (PharmD) curriculum that would improve students' Spanish language skills and cultural competence so that graduates could provide competent pharmaceutical care to Spanish-speaking patients. Five elective courses were created and introduced to the curriculum including 2 medical Spanish courses; a medical Spanish service-learning course; a 2-week Spanish language and cultural immersion trip to Mexico; and an advanced practice pharmacy experience (APPE) at a medical care clinic serving a high percentage of Spanish-speaking patients. Advisors placed increased emphasis on encouraging pharmacy students to complete a major or minor in Spanish. Enrollment in the Spanish language courses and the cultural immersion trip has been strong. Twenty-three students have completed the APPE at a Spanish-speaking clinic. Eleven percent of 2010 Butler University pharmacy graduates completed a major or minor in Spanish compared to approximately 1% in 2004 when the initiative began. A Spanish language and culture initiative started in 2004 has resulted in increased Spanish language and cultural competence among pharmacy students and recent graduates.
A longitudinal medical Spanish program at one US medical school.
Reuland, Daniel S; Frasier, Pamela Y; Slatt, Lisa M; Alemán, Marco A
2008-07-01
Policymakers have recommended recruiting or training (or both) more US physicians who can provide care in Spanish. Few longitudinal medical Spanish programs have been described and evaluated. This study aims to describe development and evaluation of the preclinical phase of a 4-y program designed to graduate physicians who can provide language-concordant care in Spanish. Study was done in one public medical school in southeastern USA. The program targeted intermediate/advanced Spanish speakers. Standardized fluency assessments were used to determine eligibility and evaluate participants' progress. Curriculum included didactic coursework, simulated patients, socio-cultural seminars, clinical skills rotations at sites serving Latinos, service-learning, and international immersion. For the first two cohorts (n = 45) qualitative evaluation identified program improvement opportunities and found participants believed the program helped them maintain their Spanish skills. Mean interim (2-y) speaking proficiency scores were unchanged from baseline: 9.0 versus 8.7 at baseline on 12-point scale (p = 0.15). Mean interim listening comprehension scores (second cohort only, n = 25) increased from a baseline of 77 to 86% (p = 0.003). Proportions "passing" the listening comprehension test increased from 72 to 92% (p = 0.06). We describe development of a longitudinal Spanish program within a medical school. Participation was associated with improved Spanish listening comprehension and no change in speaking proficiency.
Spanish? What Spanish? The Search for a 'Caribbean Standard.'
ERIC Educational Resources Information Center
Hollingsworth, C.
1978-01-01
Variations in lexicon, phonology, morphology, and syntax of Spanish as spoken in Venezuela, Cuba, Mexico, and Castile have led to a diversity in the types of Spanish taught in Caribbean schools. The Programa Interamericano de Linguistica y Ensenanza de Idiomas is conducting a survey which will provide authoritative standards for Spanish teachers.…
El Espanol como Idioma Universal (Spanish as a Universal Language)
ERIC Educational Resources Information Center
Mijares, Jose
1977-01-01
A proposal to transform Spanish into a universal language because it possesses the prerequisites: it is a living language, spoken in several countries; it is a natural language; and it uses the ordinary alphabet. Details on simplification and standardization are given. (Text is in Spanish.) (AMH)
Semantic Categorization of Placement Verbs in L1 and L2 Danish and Spanish
ERIC Educational Resources Information Center
Cadierno, Teresa; Ibarretxe-Antuñano, Iraide; Hijazo-Gascón, Alberto
2016-01-01
This study investigates semantic categorization of the meaning of placement verbs by Danish and Spanish native speakers and two groups of intermediate second language (L2) learners (Danish learners of L2 Spanish and Spanish learners of L2 Danish). Participants described 31 video clips picturing different types of placement events. Cluster analyses…
IUE observations of two late-type stars Bx Mon (M + pec) and TV Gem (M1 Iab)
NASA Technical Reports Server (NTRS)
Michalitsianos, A. G.; Hobbs, R. W.; Kafatos, M.
1981-01-01
The IUE observations of two late type stars BX Mon and TV Gem that reveal the emission properties in the ultraviolet of subluminous companions are discussed. Analysis of the continuum emission observed from BX Mon suggests the companion, is a middle A III star. High excitation emission lines observed between 1200 A and 2000 A that generally do not typify emission observed in either late M type variables or A type stars are also detected. It is suggested that these strong high excitation lines arise in a large volume of gas heated by nonradiation processes that could be the result of tidal interaction and mass exchange in the binary system. In contrast to stars such as BX Mon, the luminous M1 supergiant TV Gem shows unexpected intense UV continuum throughout the sensitivity range of IUE. The UV spectrum of TV Gem is characterized by intense continuum with broad absorption features detected in the short wavelength range. The analysis shows that the companion could be a B9 or A1 III-IV star. Alternate suggestions are presented for explaining the UV continuum in terms of an accretion disk in association with TV Gem.
Li, Zhen; Zhang, Qingwen; Zhou, Xuguo
2016-06-07
The pine wood nematode, Bursaphelenchus xylophilus, is the causal agent of pine wilt disease that has devastated pine forests in Asia. Parasitic nematodes are known to have evolved antioxidant stress responses that defend against host plant defenses. In this study, the infestation of whitebark pine, Pinus bungean, with B. xylophilus led to a significant increase in plant hydrogen peroxide (H2O2) and salicylic acid levels. Correspondingly, the expression of an antioxidative enzyme, 2-Cysteine peroxiredoxin (BxPrx), was elevated in B. xylophilus following the H2O2 treatments. Recombinant BxPrx, a thermal stabile and pH tolerant enzyme, exhibited high level of antioxidant activity against H2O2, suggesting that it is capable of protecting cells from free radical attacks. Immunohistochemical localization study showed that BxPrx was broadly expressed across different tissues and could be secreted outside the nematode. Finally, the number of BxPrx homologs in both dauer-like and fungi-feeding B. xylophilus were comparable based on bioinformatics analysis of existing EST libraries, indicating a potential role of BxPrx in both propagative and dispersal nematodes. These combined results suggest that BxPrx is a key genetic factor facilitating the infestation and distribution of B. xylophilus within pine hosts, and consequently the spread of pine wilt disease.
ERIC Educational Resources Information Center
Ulsh, Jack L.
This text is designed for native speakers of American English who have a good command of Spanish and want to acquire a knowledge of Portuguese. The manual focuses on features of Portuguese pronunciation, grammar, and vocabulary that have similar but not always identical counterparts in Spanish. Correspondences which often create interference for…
Agboola, Stephen; Jethwani, Kamal; Lopez, Lenny; Searl, Meghan; O'Keefe, Sandra; Kvedar, Joseph
2016-11-18
Text messages are increasingly being used because of the low cost and the ubiquitous nature of mobile phones to engage patients in self-care behaviors. Self-care is particularly important in achieving treatment outcomes in type 2 diabetes mellitus (T2DM). This study examined the effect of personalized text messages on physical activity, as measured by a pedometer, and clinical outcomes in a diverse population of patients with T2DM. Text to Move (TTM) incorporates physical activity monitoring and coaching to provide automated and personalized text messages to help patients with T2DM achieve their physical activity goals. A total of 126 English- or Spanish-speaking patients with glycated hemoglobin A 1c (HbA 1c ) >7 were enrolled in-person to participate in the study for 6 months and were randomized into either the intervention arm that received the full complement of the intervention or a control arm that received only pedometers. The primary outcome was change in physical activity. We also assessed the effect of the intervention on HbA 1c , weight, and participant engagement. All participants (intervention: n=64; control: n=62) were included in the analyses. The intervention group had significantly higher monthly step counts in the third (risk ratio [RR] 4.89, 95% CI 1.20 to 19.92, P=.03) and fourth (RR 6.88, 95% CI 1.21 to 39.00, P=.03) months of the study compared to the control group. However, over the 6-month follow-up period, monthly step counts did not differ statistically by group (intervention group: 9092 steps; control group: 3722 steps; RR 2.44, 95% CI 0.68 to 8.74, P=.17). HbA 1c decreased by 0.07% (95% CI -0.47 to 0.34, P=.75) in the TTM group compared to the control group. Within groups, HbA 1c decreased significantly from baseline in the TTM group by -0.43% (95% CI -0.75 to -0.12, P=.01), but nonsignificantly in the control group by -0.21% (95% CI -0.49 to 0.06, P=.13). Similar changes were observed for other secondary outcomes. Personalized text
ERIC Educational Resources Information Center
1968
This bibliography, a supplement to the 1967 catalog of 2,400 items of Spanish culture and language, includes 4,165 listings and additional categories in: (1) Spanish and Latin American authors, (2) Spanish translations of international authors, (3) fiction-library selections, (4) anthologies-complete works, (5) individual author collections, (6)…
Spanish scientific output on Helicobacter pylori. A study through Medline.
Trapero-Marugán, M; Gisbert, J P; Pajares, J M
2006-04-01
to analyze scientific output from Spanish hospitals in relation to Helicobacter pylori infection. papers collected from the Medline database between January 1988 and December 2003 were selected. Our search strategy was: "Helicobacter pylori" [MeSH] AND ((Spain [AD] OR Espana [AD] OR Spanien [AD] OR Espagne [AD] OR Espanha [AD]) OR (Spanish [LA]) OR Spain). The following was analyzed: geographic area, Spanish or foreign publication, topic, and year of publication. Output and impact bibliometric markers were evaluated. in all, 691 papers were identified, of which 241 were excluded. Number of papers went from 2 in 1988 to 47 in 2002 and 13 in 2003. There were more reports in Spanish versus foreign journals (58 vs. 42%). In the first 5 years the areas with greater output were associated with diagnosis and microbiology (33 and 20%), whereas therapy was the predominating subject during the last 5 years (27%). Original papers were most common among publications (69%). Hospitals with highest output included La Princesa (24%) and Ramón y Cajal (17.6%) in Madrid, and Parc Taulí in Barcelona (6.4%). Mean impact factor progressively increased from 1.826 in 1988 to 2.142 in 2002 and 2.493 in 2003. the production and impact of documents published by Spanish scientists regarding H. pylori infection considerably increased during the past two decades.
NASA Astrophysics Data System (ADS)
Weissglass, Christine A.
This dissertation investigates transfer and markedness in bilingual and L2 Spanish stop-rhotic sequences (e.g., the 'br' in brisa 'breeze'). It also examines the phonetics-phonology interface in Spanish. To this end, it explores the production of these sequences in two different experiments. Experiment 1 compares the production of these sequences by 6 Spanish monolinguals and 6 Spanish-Basque bilinguals. Experiment 2 does so for 25 L2 learners and 5 native Spanish speakers. Acoustic analysis of these sequences revealed that Spanish-Basque bilinguals produced trills 5% of the time whereas Spanish monolinguals did not have any trills. Additionally, fricative rhotics and coarticulation accounted for 35% of L2 realizations, but were not present in the native Spanish speaker dataset. These findings indicate a role for transfer in both bilingual and L2 phonological acquisition, although it is more prevalent in the L2 learner dataset. This is in line with the Speech Learning Model (Flege, 1995), which posits a stronger role for transfer amongst late learners (i.e., L2 learners) than early learners (i.e., Spanish-Basque bilinguals). In order to examine the role of markedness in bilingual and L2 phonological acquisition, this dissertation investigates the role of sonority in bilingual and L2 Spanish syllable structure. To do so, it proposes a sonority hierarchy for rhotic variants based on their specifications for voicing, intensity and continuancy. According to this hierarchy, approximant rhotics are the most sonorous, followed by taps, trills and fricative rhotics. Therefore, approximant rhotics were expected to be the most common realization followed by taps, trills and fricative rhotics. Although Spanish monolinguals adhered to this expectation, the other groups did not; taps were the most common realization for Spanish-Basque bilinguals, L2 learners, and native Spanish speakers and fricative rhotics were more common than trills for Spanish-Basque bilinguals and L2
Swami, Viren; García, Antonio Alías; Barron, David
2017-09-01
We examined the psychometric properties of a Spanish translation of the Body Appreciation Scale-2 (BAS-2) in a community sample of 411 women and 389 men in Almería, Spain. Participants completed the 10-item BAS-2 along with measures of appearance evaluation, body areas satisfaction, self-esteem, life satisfaction, and self-reported body mass index (BMI). Exploratory factor analyses with one split-half subsample revealed that BAS-2 scores had a one-dimensional factor structure in women and men. Confirmatory factor analysis with a second split-half subsample showed the one-dimensional factor structure had acceptable fit and was invariant across sex. There were no significant sex differences in BAS-2 scores. BAS-2 scores were significantly and positively correlated with appearance evaluation, body areas satisfaction, self-esteem, and life satisfaction. Body appreciation was significantly and negatively correlated with BMI in men, but associations in women were only significant in the second subsample. Results suggest that the Spanish BAS-2 has adequate psychometric properties. Copyright © 2017 Elsevier Ltd. All rights reserved.
Structure, Meaning, and Acquisition in Spanish: Papers from the 4th Hispanic Linguistics Symposium.
ERIC Educational Resources Information Center
Lee, James F., Ed.; Geeslin, Kimberly L., Ed.; Clemens, J. Clancy, Ed.
This collection of papers is divided into four sections. Section 1, "Historical Linguistics," includes "The Grammaticalization of Non-Dative Reflexes of Latin ill- in Spanish" (Jose R. Carrasquel) and "'Esto es Ligero de Fazer': Object to Subject Raising in Medieval and Early Modern Spanish" (Mark Davies). Section 2, "Language Acquisition and…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-20
..., Secretary, Commission, from Michael R. Trocchio, Bingham McCutchen LLP, on behalf of Pink OTC Markets Inc... Rule Change To Create a Listing Market on the Exchange October 14, 2010. On August 20, 2010, NASDAQ OMX... thereunder,\\3\\ a proposed rule change to create a listing market, which will be called ``BX.'' The proposed...
The Role of Prosodic Structure in the L2 Acquisition of Spanish Stop Lenition
ERIC Educational Resources Information Center
Cabrelli Amaro, Jennifer
2017-01-01
This study tests the hypothesis that late first-language English / second-language Spanish learners (L1 English / L2 Spanish learners) acquire spirantization in stages according to the prosodic hierarchy (Zampini, 1997, 1998). In Spanish, voiced stops [b d g] surface after a pause or nasal stop, and continuants [ß? ð? ??] surface postvocalically,…
Moz, Stefania; Basso, Daniela; Bozzato, Dania; Galozzi, Paola; Navaglia, Filippo; Negm, Ola H; Arrigoni, Giorgio; Zambon, Carlo-Federico; Padoan, Andrea; Tighe, Paddy; Todd, Ian; Franchin, Cinzia; Pedrazzoli, Sergio; Punzi, Leonardo; Plebani, Mario
2016-10-25
Epidermal Growth Factor (EGF) receptor overexpression, KRAS, TP53, CDKN2A and SMAD4 mutations characterize pancreatic ductal adenocarcinoma. This mutational landscape might influence cancer cells response to EGF, Transforming Growth Factor β1 (TGFβ1) and stromal inflammatory calcium binding proteins S100A8/A9. We investigated whether chronic exposure to EGF modifies in a SMAD4-dependent manner pancreatic cancer cell signalling, proliferation and invasion in response to EGF, TGFβ1 and S100A8/A9. BxPC3, homozigously deleted (HD) for SMAD4, and BxPC3-SMAD4+ cells were or not stimulated with EGF (100 ng/mL) for three days. EGF pre-treated and non pretreated cells were stimulated with a single dose of EGF (100 ng/mL), TGFβ1 (0,02 ng/mL), S100A8/A9 (10 nM). Signalling pathways (Reverse Phase Protein Array and western blot), cell migration (Matrigel) and cell proliferation (XTT) were evaluated. SMAD4 HD constitutively activated ERK and Wnt/β-catenin, while inhibiting PI3K/AKT pathways. These effects were antagonized by chronic EGF, which increased p-BAD (anti-apoptotic) in response to combined TGFβ1 and S100A8/A9 stimulation. SMAD4 HD underlied the inhibition of NF-κB and PI3K/AKT in response to TGFβ1 and S100A8/A9, which also induced cell migration. Chronic EGF exposure enhanced cell migration of both BxPC3 and BxPC3-SMAD4+, rendering the cells less sensitive to the other inflammatory stimuli. In conclusion, SMAD4 HD is associated with the constitutive activation of the ERK and Wnt/β-catenin signalling pathways, and favors the EGF-induced activation of multiple signalling pathways critical to cancer proliferation and invasion. TGFβ1 and S100A8/A9 mainly inhibit NF-κB and PI3K/AKT pathways and, when combined, sinergize with EGF in enhancing anti-apoptotic p-BAD in a SMAD4-dependent manner.
First-Principles Study of Novel Two-Dimensional (C4H9NH3)2PbX4 Perovskites for Solar Cell Absorbers.
Wang, Da; Wen, Bo; Zhu, Ya-Nan; Tong, Chuan-Jia; Tang, Zhen-Kun; Liu, Li-Min
2017-02-16
Low-dimensional perovskites (A 2 BX 4 ), in which the A cations are replaced by different organic cations, may be used for photovoltaic applications. In this contribution, we systematically study the two-dimensional (2D) (C 4 H 9 NH 3 ) 2 PbX 4 (X═Cl, Br and I) hybrid perovskites by density functional theory (DFT). A clear structures-properties relationship, with the photophysical characteristics directly related to the dimensionality and material compositions, was established. The strong s-p antibonding couplings in both bulk and monolayer (C 4 H 9 NH 3 ) 2 PbI 4 lead to low effective masses for both holes (m h *) and electrons (m e *). However, m h * increases in proportion to the decreasing inorganic layer thickness, which eventually leads to a slightly shifted band edge emission found in 2D perovskites. Notably, the 2D (C 4 H 9 NH 3 ) 2 PbX 4 perovskites exhibit strong optical transitions in the visible light spectrum, and the optical absorption tunings can be achieved by varying the compositions and the layer thicknesses. Such work paves an important way to uncover the structures-properties relationship in 2D perovskites.
Body fat at pubertal genital stage 2: a comparison between Spanish and Mexican boys.
Vizmanos, B; Llop-Viñolas, D; Quezada-Figueroa, N; Sánchez-Sucilla, M; Fernández-Ballart, J D; Salcedo-Rocha, A L; Vásquez-Garibay, E M; Martí-Henneberg, C
2009-06-01
To compare body fat mass at the same stage of pubertal maturation, genital stage 2 (G2), in a Spanish and in a Mexican sample of boys. Data from Spain (n=177) were from a previous longitudinal clinical follow-up and data from Mexico (n=91) from a cross-sectional study. Subjects were grouped according to the presence of G2 at similar ages. Spanish sample was divided into boys with G2 at age 12 (n=60), 13 (n=74) and 14 (n=43). In Mexican sample, 23 boys were at G2 at 12 years, 38 at age 13 and 30 at 14 years. Height, weight, upper arm circumference and four skinfold thicknesses were recorded. Genital development was assessed (Tanner scale). Sum of four skinfolds (SUM), body mass index (BMI), percentage of body fat (%BF) and extremity/trunk skinfold ratio (ETR=(triceps+biceps)/(subscapular+suprailiac)) was calculated. When comparing subjects with different ages at G2 from the same country, or with the same age at G2 from different countries, no significant differences were found in adiposity variables (%BF, SUM), nor in BMI. Nevertheless, there were differences in body fat distribution: ETR was higher in Spanish boys (P<0.001), because of their greater triceps skinfold thickness (P=0.013), and due to the greater trunk fat stores in Mexican boys (P<0.01, subscapular and suprailiac skinfolds). There is a subcutaneous fat mass store characteristic of G2 in boys, which is not only independent of age, but is also observable in two different populations.
Evaluating the Discriminant Accuracy of a Grammatical Measure With Spanish-Speaking Children
Gutiérrez-Clellen, Vera F.; Restrepo, M. Adelaida; Simón-Cereijido, Gabriela
2012-01-01
Purpose The purpose of this study was to evaluate the discriminant accuracy of a grammatical measure for the identification of language impairment in Latino Spanish-speaking children. The authors hypothesized that if exposure to and use of English as a second language have an effect on the first language, bilingual children might exhibit lower rates of grammatical accuracy than their peers and be more likely to be misclassified. Method Eighty children with typical language development and 80 with language impairment were sampled from 4 different geographical regions and compared using linear discriminant function analysis. Results Results indicated fair-to-good sensitivity from 4;0 to 5;1 years, good sensitivity from 5;2 to 5;11 years, and poor sensitivity above age 6 years. The discriminant functions derived from the exploratory studies were able to predict group membership in confirmatory analyses with fair-to-excellent sensitivity up to age 6 years. Children who were bilingual did not show lower scores and were not more likely to be misclassified compared with their Spanish-only peers. Conclusions The measure seems to be appropriate for identifying language impairment in either Spanish-dominant or Spanish-only speakers between 4 and 6 years of age. However, for older children, supplemental testing is necessary. PMID:17197491
Muñoz-Soler, Verónica; Flores-López, María José; Cabañero-Martínez, María José; Richart-Martínez, Miguel
2007-01-01
To compare Spanish nursing journals with 2 English-language standard journals, as well as Spanish journals in closely related disciplines, to identify possible quantitative and qualitative shortcomings in scientific documentation. We performed a descriptive, cross-sectional study of the references contained in 796 articles from 6 Spanish journals from 3 health disciplines (2000-2002) and 2 English-language nursing journals (2000-2001). The number of references, type of publication cited, and language of the document cited were compared in individual journals, and in journals grouped by discipline and according to language. Spanish-language nursing journals had the lowest mean number of references per article (X- = 16.20) when compared with psychology journals (X- = 31.24), medical journals (X- = 31.39) and international nursing journals (X- = 37.11). Among Spanish journals, citation of English-language publications was most frequent in medical journals (X- = 26.28) and least frequent in nursing journals (X- = 6.04). In contrast, citation of Spanish documents was most frequent in nursing journals (X- = 9.79) and least frequent in medical journals (X- = 4.43). Although scientific publication of Spanish nursing has improved, it is not comparable to publication of closely related disciplines and international nursing. The low citation of English documents clearly reveals the risk of scientific insularity.
Subject-to-Subject Raising and the Syntax of Tense in L2 Spanish: A Full Access Approach
ERIC Educational Resources Information Center
Campos-Dintrans, Gonzalo; Pires, Acrisio; Rothman, Jason
2014-01-01
This paper investigates the acquisition of syntax in L2 grammars. We tested adult L2 speakers of Spanish (English L1) on the feature specification of T(ense), which is different in English and Spanish in so-called subject-to-subject raising structures. We present experimental results with the verb parecer "to seem/to appear" in different…
Ochoa, M C; Azcona, C; Biebermann, H; Brumm, H; Razquin, C; Wermter, A-K; Martínez, J A; Hebebrand, J; Hinney, A; Moreno-Aliaga, M J; Marti, A; Patiño, A; Chueca, M; Oyarzabal, M; Pelach, R
2007-05-01
The melanocortin 4 receptor gene (MC4R) is involved in body weight regulation. While many studies associated MC4R mutations with childhood obesity, information on MC4R mutations in Spanish children and adolescents is lacking. Our objective was to screen a population of children and adolescents from the north of Spain (Navarra) for MC4R mutations and to study the phenotypes of carriers and their families. In addition, functional assays were performed for a novel MC4R mutation. The study was composed of 451 Spanish children and adolescents (49% boys), aged 5-18 year. According to the International Obesity Task Force (IOTF) criteria, the groups included 160 obese, 132 overweight and 159 normal-weight control subjects. One novel (Thr162Arg) and three known nonsynonymous mutations in the MC4R gene (Ser30Phe, Thr150Ile, Ala244Glu) were detected heterozygously. The MC4R mutations were found in three male (one obese and two overweight) and two female subjects (one obese and one overweight). The novel mutation did not appear to lead to an impaired receptor function. An unequivocal relationship of MC4R mutations with obesity in pedigrees together with an impaired function of the encoded receptor could not be established for any of the mutations. The presence of heterozygous MC4R mutations in obese and overweight subjects indicates that these mutations may be a susceptibility factor for obesity development, but lifestyle factors, such as exercise or sedentary activities, may modify their effect.
Paloma, E; Martínez-Mir, A; Vilageliu, L; Gonzàlez-Duarte, R; Balcells, S
2001-06-01
The ABCA4 gene has been involved in several forms of inherited macular dystrophy. In order to further characterize the complex genotype-phenotype relationships involving this gene, we have performed a mutation analysis of ABCA4 in 14 Spanish patients comprising eight STGD (Stargardt), four FFM (fundus flavimaculatus), and two CRD (Cone-rod dystrophy) patients. SSCP (single-strand conformation polymorphism) analysis and DNA sequencing of the coding and 5' upstream regions of this gene allowed the identification of 16 putatively pathogenic alterations, nine of which are novel. Most of these were missense changes, and no patient was found to carry two null alleles. Overall, the new data agree with a working model relating the different pathogenic phenotypes to the severity of the mutations. When considering the information presented here together with that of previous reports, a picture of the geographic distribution of three particular mutations emerges. The R212C change has been found in French, Italian, Dutch, German, and Spanish but not in British patients. In the Spanish collection, R212C was found in a CRD patient, indicating that it may be a rather severe change. In contrast, c.2588G>C, a very common mild allele in the Dutch population, is rarely found in Southern Europe. Interestingly, the c.2588G>C mutation has been found in a double mutant allele together with the missense R1055W. Finally, the newly described L1940P was found in two unrelated Spanish patients, and may be a moderate to severe allele. Copyright 2001 Wiley-Liss, Inc.
L2 Acquisition of Spanish Dative Clitics by English and Dutch Learners
ERIC Educational Resources Information Center
Escobar-Álvarez, M. Ángeles
2017-01-01
This article examines the second language acquisition (SLA) of Spanish dative clitics in clitic doubling (CLD) structures that are closely related to the double object construction (DOC) in English and Dutch. It also addresses the question of how adult English and Dutch speakers learning L2 Spanish in a formal setting develop knowledge and use of…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-24
... Organizations; Notice of Filing of a Proposed Rule Change by NASDAQ OMX BX, Inc. To Adopt Rule 4120(a)(11) Concerning Individual Stock Trading Pauses and To Adopt Related IM-4120-3 May 19, 2010. Pursuant to Section... Change The Exchange is filing this proposed rule change to adopt Rule 4120(a)(11) concerning individual...
Martin, Allison N; Marino, Miguel; Killerby, Marie; Rosselli-Risal, Liliana; Isom, Kellene A; Robinson, Malcolm K
2017-06-01
Bariatric centers frequently provide preoperative educational programs to inform patients about the risks and benefits of weight loss surgery. However, most programs are conducted in English, which may create barriers to effective treatment and access to care for non-English speaking populations. To address this concern, we instituted a comprehensive Spanish-language education program consisting of preoperative information and group nutrition classes conducted entirely in, and supported with Spanish-language materials. The primary aim was to examine the effect of this intervention on Spanish-speaking patients' decision to undergo surgery in a pilot study. University Hospital/Community Health Center, United States. Three cohorts of patients seeking bariatric surgery between January 1, 2011 and March 31, 2012 were identified: 1) primary English speakers attending English-language programs ("English-English"); 2) primary Spanish speakers attending Spanish-language programs ("Spanish-Spanish"); and 3) primary Spanish speakers attending English-speaking programs with the assistance of a Spanish-to-English translator ("Spanish-English"). 26% of the English-English cohort ultimately underwent surgery compared with only 12% of the Spanish-Spanish cohort (P = .009). Compared with the English-English group, time to surgery was 35 days longer for the Spanish-Spanish and 185 days longer for the Spanish-English group (both P< .001). Spanish-speaking patients were less likely to undergo bariatric surgery regardless of the language in which educational sessions are provided. For those choosing surgery, providing Spanish-language sessions can shorten time to surgery. A barrier to effective obesity treatment may exist for Spanish speakers, which may be only partially overcome by providing support in Spanish. Copyright © 2017. Published by Elsevier Inc.
Echeverri, Margarita; Anderson, David; Nápoles, Anna María
2016-01-01
This article describes the adaptation and initial validation of the Cancer Health Literacy Test (CHLT) for Spanish speakers. A cross-sectional field test of the Spanish version of the CHLT (CHLT-30-DKspa) was conducted among healthy Latinos in Louisiana. Diagonally weighted least squares was used to confirm the factor structure. Item response analysis using 2-parameter logistic estimates was used to identify questions that may require modification to avoid bias. Cronbach's alpha coefficients estimated scale internal consistency reliability. Analysis of variance was used to test for significant differences in CHLT-30-DKspa scores by gender, origin, age and education. The mean CHLT-30-DKspa score (N = 400) was 17.13 (range = 0-30, SD = 6.65). Results confirmed a unidimensional structure, χ(2)(405) = 461.55, p = .027, comparative fit index = .993, Tucker-Lewis index = .992, root mean square error of approximation = .0180. Cronbach's alpha was .88. Items Q1-High Calorie and Q15-Tumor Spread had the lowest item-scale correlations (.148 and .288, respectively) and standardized factor loadings (.152 and .302, respectively). Items Q19-Smoking Risk, Q8-Palliative Care, and Q1-High Calorie had the highest item difficulty parameters (difficulty = 1.12, 1.21, and 2.40, respectively). Results generally support the applicability of the CHLT-30-DKspa for healthy Spanish-speaking populations, with the exception of 4 items that need to be deleted or revised and further studied: Q1, Q8, Q15, and Q19.
Inglaterra, primitiva colonia espanola (England, Primitive Spanish Colony)
ERIC Educational Resources Information Center
Til, Brianes
1975-01-01
The author fantasizes that at some point in the distant past England was a Spanish colony. He supports his thesis by revealing fantastic etymologies of some English place names showing the influence of Spanish on English, for example "Surrey" comes from "su rey." (Text is in Spanish.) (TL)
NASA Astrophysics Data System (ADS)
Hull, Alexander W.; Field, Robert W.; Ono, Shuhei
2017-06-01
Sulfur mass independent fractionation (S-MIF) describes anomalous sulfur isotope ratios commonly found in sedimentary rocks older than 2.45 billion years. These anomalies likely originate from photochemistry of small, sulfur-containing molecules in the atmosphere, and their sudden disappearance from rock samples younger than 2.45 years is thought to be correlated with a sharp rise in atmospheric oxygen levels. The emergence of atmospheric oxygen is an important milestone in the development of life on Earth, but the mechanism for sulfur MIF in an anoxic atmosphere is not well understood. In this context, we present an analysis of the B-X UV spectrum of S_{2}, an extension of work presented last year. The B state of S_{2} is strongly perturbed by the nearby B" state, as originally described by Green and Western (1996). Our analysis suggests that a doorway-mediated transfer mechanism shifts excited state population from the short-lifetime B state to the longer-lifetime B" state. Furthermore, access to the perturbed doorway states is strongly dependent on the population distribution in the ground state. This suggests that the temperature of the Achaean atmosphere may have played a significant role in determining the extent of S-MIF.
ERIC Educational Resources Information Center
Bowden, Harriet Wood; Gelfand, Matthew P.; Sanz, Cristina; Ullman, Michael T.
2010-01-01
This study examines the storage versus composition of Spanish inflected verbal forms in first language (L1) and second language (L2) speakers of Spanish. L2 participants were selected to have mid-to-advanced proficiency, high classroom experience, and low immersion experience, typical of medium-to-advanced foreign language learners. Participants…
Experiencing the body during pregnancy: A qualitative research study among Spanish sportswomen.
Martinez-Pascual, Beatriz; Abuín-Porras, Vanesa; Pérez-de-Heredia-Torres, Marta; Martínez-Piedrola, Rosa María; Fernández-de-las-Peñas, César; Palacios-Ceña, Domingo
2016-01-01
The aim of the current qualitative phenomenological study was to describe the body experiences during pregnancy among Spanish elite sportswomen. Twenty Spanish sportswomen with the following criteria were included: (1) aged between 18 and 65 years; (2) had been pregnant during their professional sporting career; and (3) after the end of their pregnancy, had returned to their professional sports career for at least 1 year. A qualitative thematic analysis was conducted. Data were collected from May 2010 to April 2012 using in-depth personal interviews, investigator's field notes, and extracts from the participants' personal letters. Identified themes included: (1) a new body; (2) body control; (3) to feel their bodies and communicate with them; and (4) body's beauty ideal. Understanding the meaning of the body experience for elite Spanish sportswomen might provide us with deeper insight into their expectations and might help in the development of training systems focused on them.
SCDC Spanish Curricula Units. Science/Math Strand, Unit 4, Grade 2, Supplements & Ditto Packet.
ERIC Educational Resources Information Center
Spanish Curricula Development Center, Miami Beach, FL.
Designed for use with unit four of the science/math strand for second graders, the supplement and ditto packet contain visuals, worksheets, and instructional aids referred to in the teacher's guide corresponding to this unit. The brief introductions to kits 13-16 are written in both English and Spanish; all classroom materials for students are in…
Tipster Text Phase 2 Architecture Design
1996-06-19
TIPSTER Text Phase II Architecture Design Version 2.1p 19 June 1996 Ralph Grishman New York University grishman @cs.nyu.edu and the TIPSTER...1996 2. REPORT TYPE 3. DATES COVERED 00-00-1996 to 00-00-1996 4. TITLE AND SUBTITLE TIPSTER Text Phase II Architecture Design 5a. CONTRACT
Experimental Investigations of Space Shuttle BX-265 Foam
NASA Technical Reports Server (NTRS)
Lerch, Bradley A.; Sullivan, Roy M.
2009-01-01
This report presents a variety of experimental studies on the polyurethane foam, BX-265. This foam is used as a close-out foam insulation on the space shuttle external tank. The purpose of this work is to provide a better understanding of the foam s behavior and to support advanced modeling efforts. The following experiments were performed: Thermal expansion was measured for various heating rates. The in situ expansion of foam cells was documented by heating the foam in a scanning electron microscope. Expansion mechanisms are described. Thermogravimetric analysis was performed at various heating rates and for various environments. The glass transition temperature was also measured. The effects of moisture on the foam were studied. Time-dependent effects were measured to give preliminary data on viscoelastoplastic properties.
Hawks, Brian W.; Li, Wei; Garlow, Steven J.
2009-01-01
Cocaine-Amphetamine Regulated Transcript (CART) peptides are implicated in a wide range of behaviors including in the reinforcing properties of psychostimulants, feeding and energy balance and stress and anxiety responses. We conducted a complex trait analysis to examine natural variation in the regulation of CART transcript abundance (CARTta) in the hypothalamus. CART transcript abundance was measured in total hypothalamic RNA from 26 BxD recombinant inbred (RI) mouse strains and in the C57BL/6 (B6) and DBA/2J (D2) progenitor strains. The strain distribution pattern for CARTta was continuous across the RI panel, which is consistent with this being a quantitative trait. Marker regression and interval mapping revealed significant quantitative trait loci (QTL) on mouse chromosome 4 (around 58.2cM) and chromosome 11 (between 20–36cM) that influence CARTta and account for 31% of the between strain variance in this phenotype. There are numerous candidate genes and QTL in these chromosomal regions that may indicate shared genetic regulation between CART expression and other neurobiological processes referable to known actions of this neuropeptide. PMID:18199428
Rhone, J A; Waldron, D F; Herring, A D
2013-10-01
Production records from 291 Boer-Spanish and Spanish does, collected between 1994 and 2004 in the Edwards Plateau region of West Texas, were examined to compare Boer-Spanish and Spanish does for body weights, fertility, prolificacy, and number of kids weaned. Traits were analyzed using single-trait mixed models. Boer-Spanish does were heavier at birth than Spanish does (2.79 vs. 2.67 kg, P = 0.05) but similar weight at weaning (15.2 vs. 15.0 kg, P = 0.59). Boer-Spanish does had a heavier body weight at breeding than Spanish does (46.5 vs. 43.5 kg, P < 0.01). Boer-Spanish does had similar fertility over 8 annual breeding seasons (0.87 vs. 0.84, P = .22). Boer-Spanish does had an advantage over Spanish does for fertility to a 30-d breeding season (0.53 vs. 0.48; P = .09). Boer-Spanish does produced more kids than Spanish does (1.70 vs. 1.62, P = .09). Boer-Spanish does weaned a similar number of kids (1.30 vs. 1.31, P = .76). Age of doe significantly affected (P < 0.05) both number of kids born and number of kids weaned, with older does giving birth to, and weaning, more kids. Boer-Spanish does had greater birth weight, body weight at breeding, and number of kids born than Spanish does. Boer-Spanish does had a similar number of kids weaned as Spanish does.
Text4baby: development and implementation of a national text messaging health information service.
Whittaker, Robyn; Matoff-Stepp, Sabrina; Meehan, Judy; Kendrick, Juliette; Jordan, Elizabeth; Stange, Paul; Cash, Amanda; Meyer, Paul; Baitty, Julie; Johnson, Pamela; Ratzan, Scott; Rhee, Kyu
2012-12-01
Text4baby is the first free national health text messaging service in the United States that aims to provide timely information to pregnant women and new mothers to help them improve their health and the health of their babies. Here we describe the development of the text messages and the large public-private partnership that led to the national launch of the service in 2010. Promotion at the local, state, and national levels produced rapid uptake across the United States. More than 320,000 people enrolled with text4baby between February 2010 and March 2012. Further evaluations of the effectiveness of the service are ongoing; however, important lessons can be learned from its development and uptake.
Moz, Stefania; Basso, Daniela; Bozzato, Dania; Galozzi, Paola; Navaglia, Filippo; Negm, Ola H.; Arrigoni, Giorgio; Zambon, Carlo-Federico; Padoan, Andrea; Tighe, Paddy; Todd, Ian; Franchin, Cinzia; Pedrazzoli, Sergio; Punzi, Leonardo; Plebani, Mario
2016-01-01
Epidermal Growth Factor (EGF) receptor overexpression, KRAS, TP53, CDKN2A and SMAD4 mutations characterize pancreatic ductal adenocarcinoma. This mutational landscape might influence cancer cells response to EGF, Transforming Growth Factor β1 (TGFβ1) and stromal inflammatory calcium binding proteins S100A8/A9. We investigated whether chronic exposure to EGF modifies in a SMAD4-dependent manner pancreatic cancer cell signalling, proliferation and invasion in response to EGF, TGFβ1 and S100A8/A9. BxPC3, homozigously deleted (HD) for SMAD4, and BxPC3-SMAD4+ cells were or not stimulated with EGF (100 ng/mL) for three days. EGF pre-treated and non pretreated cells were stimulated with a single dose of EGF (100 ng/mL), TGFβ1 (0,02 ng/mL), S100A8/A9 (10 nM). Signalling pathways (Reverse Phase Protein Array and western blot), cell migration (Matrigel) and cell proliferation (XTT) were evaluated. SMAD4 HD constitutively activated ERK and Wnt/β-catenin, while inhibiting PI3K/AKT pathways. These effects were antagonized by chronic EGF, which increased p-BAD (anti-apoptotic) in response to combined TGFβ1 and S100A8/A9 stimulation. SMAD4 HD underlied the inhibition of NF-κB and PI3K/AKT in response to TGFβ1 and S100A8/A9, which also induced cell migration. Chronic EGF exposure enhanced cell migration of both BxPC3 and BxPC3-SMAD4+, rendering the cells less sensitive to the other inflammatory stimuli. In conclusion, SMAD4 HD is associated with the constitutive activation of the ERK and Wnt/β-catenin signalling pathways, and favors the EGF-induced activation of multiple signalling pathways critical to cancer proliferation and invasion. TGFβ1 and S100A8/A9 mainly inhibit NF-κB and PI3K/AKT pathways and, when combined, sinergize with EGF in enhancing anti-apoptotic p-BAD in a SMAD4-dependent manner. PMID:27655713
Programa de lengua espanola: Guia para el profesor, 2 (Spanish Language Program: Teacher's Guide 2).
ERIC Educational Resources Information Center
Martinez, Emiliano; And Others
This teacher's guide is designed for use with "La Ciudad" and "Otros Amigos, Otras Culturas," two textbooks in the second part of the Spanish language series of readers. It contains lesson plans to enable the teacher to make better use of the texts and includes illustrations taken from each of the books themselves. (SK)
Text4baby: Development and Implementation of a National Text Messaging Health Information Service
Whittaker, Robyn; Meehan, Judy; Jordan, Elizabeth; Stange, Paul; Cash, Amanda; Meyer, Paul; Baitty, Julie; Johnson, Pamela; Ratzan, Scott; Rhee, Kyu
2012-01-01
Text4baby is the first free national health text messaging service in the United States that aims to provide timely information to pregnant women and new mothers to help them improve their health and the health of their babies. Here we describe the development of the text messages and the large public–private partnership that led to the national launch of the service in 2010. Promotion at the local, state, and national levels produced rapid uptake across the United States. More than 320 000 people enrolled with text4baby between February 2010 and March 2012. Further evaluations of the effectiveness of the service are ongoing; however, important lessons can be learned from its development and uptake. PMID:23078509
Ramos, Juan José; Huetos, Olga; González, Sara; Esteban, Marta; Calvo, Eva; Pérez-Gómez, Beatriz; Castaño, Argelia
2017-03-01
Organochlorinated pesticides (OCPs) were measured in a representative sample of Spanish adults within the Bioambient.es project, a nationwide human biomonitoring program promoted by Spanish Ministry of Agriculture, Food and Environment. The objective of Bioambient.es is to establish reference levels of environmental pollutants in the general population. Participants were recruited in 2009-2010 during their annual medical examination at work. Serum levels of thirteen OCPs were investigated: Aldrin, endrin, dieldrin, heptachlor, heptachlor-epoxide, dichlorodiphenyldichloroethylenes (DDEs), hexachlorobenzene (HCB), dichlorodiphenyltrichloroethanes (DDTs) and hexachlorocyclohexanes (HCHs) The highest concentrations were observed for DDE, HCB and β-HCH. The 95th percentile, in ng/g lipids, were: 717.7 for 4,4-DDE, 160.4 for HCB and 107.2 for β-HCH, while concentrations of aldrin, endrin, heptachlor, α-HCH, 2,4-DDT, 4,4-DDT and 2,4-DDE were markedly lower and detected in less than 10% of the samples. Significant differences (p<0.05) were found for DDE and HCB and seasonality, gender and age. Analyzing the geographical distribution, participants from the north of Spain had highest levels of HCB while those from the center of Spain had highest levels of 4,4-DDE. Comparing to earlier studies, the results indicated a sharp decline in the OCP concentrations in the Spanish population over time, and today values are in the same range or lower than those reported in similar studies worldwide, except for HCHs and HCB that presented higher levels than in other European countries and much higher than those observed in US and Canada. This study represents the first nationwide survey of exposure to OCPs in Spain and provides a background reference range for exposure to OCPs in the Spanish adult occupied population. These results will allow establishing reference values, observing temporal trends and identifying high exposure groups. Copyright © 2016 Elsevier GmbH. All rights
Development of a Spanish version of the "Backache Index".
Cuesta-Vargas, Antonio; Gonzaleaz-Sanchez, Manuel; Farasyn, Andre
2010-01-01
found between IDE-1 (4.65 ± 4.15 ) and IDE-2 (4.72 ± 4.20) and the absolute reliability was perfect with an ICC=0.97. The IDE form facilitates a better diffusion under the Spanish speaking population, allowing it to maintain the degree of homogenenity and acceptance that the "Indice de Dolor de Espalda" or IDE has in clinical practice, helping to spread among the Hispanic world one of the objectives that the creator of this index raised when it was developed.
Paginas del estudiante de espanol (Pages for the Student of Spanish)
ERIC Educational Resources Information Center
Carballo Picazo, Alfredo
1975-01-01
The fifteenth in a series of workbook lessons, this consists of a passage in Spanish concerning the Spanish city of Avila. Following are exercises on vocabulary and passives in English and Spanish to be completed by the student. (Text is in English and Spanish.) (CK)
Drafting. A Bilingual Text = Dibujo Mecanico. Un Texto Bilingue.
ERIC Educational Resources Information Center
Los Angeles Unified School District, CA. Div. of Career and Continuing Education.
This bilingual instructional text, one in a series of six texts covering various vocational and technical topics, provides secondary level English and Spanish instruction in drafting. Addressed in the individual units are the following topics: safety, drafting tools and techniques, sketching, geometric construction, working drawings, sectioning,…
Iglesias, Carlos; Banker, Manish; Mahajan, Nalini; Herrero, Leyre; Meseguer, Marcos; Garcia-Velasco, Juan A
2014-07-01
To investigate differences in ovarian reserve markers (antimüllerian hormone [AMH] and antral follicle count [AFC]) in Indian and Spanish women. Cross-sectional study. In vitro fertilization (IVF) clinics. Infertile Spanish (n=229) and Indian (n=236) women who underwent controlled ovarian stimulation for IVF from January to October 2012. None. Data on ovarian reserve markers and results after ovarian stimulation were collected. The mean age of women undergoing their first or second IVF cycle was significantly higher in Spanish than in Indian women (37.5±3.3 years vs. 31.5±3.8 years). Despite this 6-year age gap, AFCs were similar (9.5±4.7 vs. 9.9±4.6), as were day 3 FSH levels (7.5±4.5 IU/L vs. 6.9±2.3 IU/L). AMH levels were slightly lower in Spanish women (1.6±1.7 ng/mL vs. 2.5±1.6 ng/mL). Multivariate regression analysis showed that being Indian decreased AFC by 2.3, such that AFC in Indian women was similar to that in Spanish women 6.3 years older (95% confidence interval 3.39-1.10). Similar ovarian reserve markers and ovarian response were observed in women with a 6-year age difference in favor of the Spanish, suggesting ethnic differences in ovarian aging. Further research is needed to understand whether these differences are genetically induced or are caused by other variables, such as nutrition. Our results may help clinicians to counsel infertile women when discussing assisted reproductive technology outcomes according to age and ethnic background. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
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2013-01-17
... ordered by customers using the CoLo Console \\3\\ during the months of January and February of 2013... number of cabinets continues to exceed the Baseline Number. \\3\\ The ``CoLo Console'' is BX's web-based...
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2010-11-12
... month.[the following charges: $285/hour--For Active Connection testing using current Exchange access... using current Exchange access protocols; $333/hour--For Active Connection testing using current Exchange... a fee of $285 per hour for active connection testing using current BX access protocols during the...
Berridge, Clara
2014-01-01
Background Mobile health interventions are often standardized and assumed to work the same for all users; however, we may be missing cultural differences in the experiences of interventions that may impact how and if an intervention is effective. Objective The objective of the study was to assess qualitative feedback from participants to determine if there were differences between Spanish speakers and English speakers. Daily text messages were sent to patients as an adjunct to group Cognitive Behavioral Therapy (CBT) for depression. Methods Messages inquired about mood and about specific themes (thoughts, activities, social interactions) of a manualized group CBT intervention. There were thirty-nine patients who participated in the text messaging pilot study. The average age of the participants was 53 years (SD 10.4; range of 23-72). Results Qualitative feedback from Spanish speakers highlighted feelings of social support, whereas English speakers noted increased introspection and self-awareness of their mood state. Conclusions These cultural differences should be explored further, as they may impact the effect of supportive mobile health interventions. Trial Registration Trial Registration: Clinicaltrials.gov NCT01083628; http://clinicaltrials.gov/ct2/show/study/NCT01083628 (Archived by WebCite at http://www.webcitation.org/6StpbdHuq). PMID:25373390
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2013-08-16
... into the System for execution. Each of BX's current connection offerings uses different switches... 10Gb Ultra low latency fiber connection option, and provide a waiver of installation fees for... to the Exchange, including a 40Gb fiber connection, a 10Gb fiber connection, a 1Gb fiber connection...
Las uniones conjuntivas en espanol (Conjunctive Correspondences in Spanish)
ERIC Educational Resources Information Center
Perez Botero, Luis
1977-01-01
This study of the medieval Spanish concept of order examines uses made of the word "y" ("and") in Spanish medieval writing to join words and phrases connoting social, natural and human order. (Text is in Spanish.) (CHK)
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2012-10-17
... a fully automated, price/time priority execution system built on the core functionality of the... orders in price/time priority without regard to the status of the entities that are entering orders. The BX Options market closely resembles NOM, including, most prominently, by offering true price/time...
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2013-02-26
... Relating to a Pricing Clarification February 19, 2013. Pursuant to Section 19(b)(1) of the Securities... Exchange proposes to add references to certain terms in Chapter XV, entitled ``Options Pricing.'' The... Options Market Maker pricing in all securities, the Participant must be registered as a BX Options Market...
Spanish Basic Course: Units 46-55.
ERIC Educational Resources Information Center
Trease, B. David; Ulsh, Jack L.
This final volume in a series of four texts was prepared as an intensive language course in Spanish for Foreign Service Officers and other United States government agencies involved in foreign affairs who need to learn to speak Spanish. This volume differs from the first three primarily in that it is geared to advanced students whose…
Manual of Tape Scripts: Spanish, Level 2. Curriculum Bulletin, 1968-69 Series, Number 13.
ERIC Educational Resources Information Center
Lipton, Gladys; And Others
This second manual of tape scripts, together with a set of foreign language audio tapes for level 2 Spanish, was prepared to support the curriculum bulletin, New York City Foreign Language Program for Secondary Schools: Spanish, Levels 1-5. Vocabulary, repetition, transformation, and recombination drills on specific grammatical features allow…
Development and preliminary evaluation of a pediatric Spanish/English speech perception task
Calandruccio, Lauren; Gomez, Bianca; Buss, Emily; Leibold, Lori J.
2014-01-01
Purpose To develop a task to evaluate children’s English and Spanish speech perception abilities in either noise or competing speech maskers. Methods Eight bilingual Spanish/English and eight age matched monolingual English children (ages 4.9 –16.4 years) were tested. A forced-choice, picture-pointing paradigm was selected for adaptively estimating masked speech reception thresholds. Speech stimuli were spoken by simultaneous bilingual Spanish/English talkers. The target stimuli were thirty disyllabic English and Spanish words, familiar to five-year-olds, and easily illustrated. Competing stimuli included either two-talker English or two-talker Spanish speech (corresponding to target language) and spectrally matched noise. Results For both groups of children, regardless of test language, performance was significantly worse for the two-talker than the noise masker. No difference in performance was found between bilingual and monolingual children. Bilingual children performed significantly better in English than in Spanish in competing speech. For all listening conditions, performance improved with increasing age. Conclusions Results indicate that the stimuli and task are appropriate for speech recognition testing in both languages, providing a more conventional measure of speech-in-noise perception as well as a measure of complex listening. Further research is needed to determine performance for Spanish-dominant listeners and to evaluate the feasibility of implementation into routine clinical use. PMID:24686915
Espanol para Hoteleria y Turismo = Spanish for Travel and Tourism.
ERIC Educational Resources Information Center
Montes, Yara G.
This beginning through advanced Spanish text includes grammar explanations, readings, and exercises with the emphasis on situations involving travel and tourism. The introductory lesson covers the Spanish language, the importance of Spanish in the United States, the Spanish alphabet, pronunciation, capitalization, punctuation, syllabication,…
Language Use in a Spanish-English Dual Immersion Classroom: A Sociolinguistic Perspective.
ERIC Educational Resources Information Center
Potowski, Kimberly
Dual immersion classrooms combine students who speak a non-English language (in this case Spanish) with English speaking students learning the native language of the nonnative English speaking students. This case study recorded the output of Spanish first language (L1) and second language (L2) fifth graders over 5 months of Spanish language…
From Number Agreement to the Subjunctive: Evidence for Processability Theory in L2 Spanish
ERIC Educational Resources Information Center
Bonilla, Carrie L.
2015-01-01
This article contributes to typological plausibility of Processability Theory (PT) (Pienemann, 1998, 2005) by providing empirical data that show that the stages predicted by PT are followed in the second language (L2) acquisition of Spanish syntax and morphology. In the present article, the PT stages for L2 Spanish morphology and syntax are first…
Development of advanced materials composites for use as insulations for LH2 tanks
NASA Technical Reports Server (NTRS)
Lemons, C. R.; Watts, C. R.; Salmassy, O. K.
1972-01-01
A study of internal insulation materials and fabrication processes for space shuttle LH2 tanks is reported. Emphasis was placed on an insulation system capable of reentry and multiple reuse in the Shuttle environment. Results are given on the optimization and manufacturing process scale-up of a 3D fiberreinforced foam insulation, BX-251-3D, derived from the Saturn S-4B internal insulation. It is shown that BX-251-3D can be satisfactorily installed in large-scale tanks under conditions that will permit a significant cost saving over the existing S-4B technology.
Restrepo, M Adelaida; Castilla, Anny P; Schwanenflugel, Paula J; Neuharth-Pritchett, Stacey; Hamilton, Claire E; Arboleda, Alejandra
2010-01-01
The purpose of this study was to examine the effects of a supplemental Spanish language instruction program for children who spoke Spanish as their native language and were attending English-only preschool programs. Specifically, the study evaluated the program's effects on the children's Spanish sentence length in words, subordination index, and grammaticality of sentences. Forty-five Spanish-speaking children attending English-only prekindergarten classrooms were selected for study. Of those, 15 children received 30 min of Spanish instruction 5 days a week for 16 weeks. The program targeted 5-10 vocabulary words a week, dialogic book reading, phonemic awareness, and letter knowledge. The remaining 30 children participated in regular preschool English instruction. Students were evaluated before intervention, immediately after intervention, and 4 months following intervention. Repeated measures analyses of variance indicated that the children who received the small-group supplemental Spanish language instruction made significant gains in their Spanish sentence length in words and subordination index when compared to those receiving regular English-only classroom instruction. There were no differences in the children's grammaticality of sentences. The findings demonstrate that a daily short native language program has significant effects on sentence length in words and subordination index in English language learners who are attending English-only preschool programs.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-05
.... Purpose The Exchange is proposing to adopt the new QView service. QView is a web-based, front-end... dashboard interface. The dashboard also allows a QView subscriber to track his/her executions and open...-based tool that, among other things, allows users access to all of the BX order and execution...
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2013-03-13
... NMS (i.e. ``dark venues'' or ``dark pools''). BCST orders, pursuant to Rule 4758(a)(1)(A)(ix), check the System for available shares and simultaneously route to select dark venues and to certain low cost... charged for such executions, including its own costs. As a general matter, BX believes that the proposed...
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2011-05-12
... 8, 2010.\\3\\ The Commission subsequently extended the time period in which to either approve the... BX Venture Market will have minimal quantitative listing standards, but will have qualitative... another national securities exchange for failure to meet quantitative listing standards (including price...
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2012-05-23
... discovery, and in fact may create investor confusion about the extent of trading interest in a stock. In... multiple orders at different price levels to move the price of a stock. While BX has an active program to... manipulation. The fee will be imposed on market participant identifiers (``MPID'') that have characteristics...
Vallejo, Miguel A; Vallejo-Slocker, Laura; Fernández-Abascal, Enrique G; Mañanes, Guillermo
2018-01-01
Objective: Stress perception depends on cultural and social aspects that vary from one country to another. One of the most widely disseminated methods of assessing psychological stress is the Perceived Stress Scale (PSS-4). Therefore, in order to identify these factors and their impact on mental health, the present study compares the PSS-4 results among three European countries (Great Britain, France and Spain). This study focuses on PSS-4 results within a Spanish sample to determine: (1) normative data, reliability and validity of PSS-4 in a Spanish sample and (2) how stress perception changes depending on cultural and social factors. Methods: The data were obtained from a website representing a service of a smoking cessation program, the study represented a service that was open to all individuals. The number of participants were 37,451. They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R). Results: The PSS-4 scores could differentiate between relevant sociodemographic variables (such as sex, age, nationality, marital status, education, parental status, employment status, and income class). The PSS-4 scores showed a positive correlation with the SCL 90-R anxiety and depression scales. The normed values for interpreting the PSS-4 scores are presented. The PSS-4 showed adequate internal consistency and reliability. Conclusions: The PSS-4 is a useful instrument for assessing stress perception levels in the general population in different countries. Its internal consistency is sufficient for a 4-item scale.
Multiple online victimization of Spanish adolescents: Results from a community sample.
Montiel, Irene; Carbonell, Enrique; Pereda, Noemí
2016-02-01
Little is known about online victimization of Spanish adolescents. The present study aims to determine the past-year prevalence of online victimization in a community sample of Spanish adolescents. The final sample consisted of 3,897 adolescents between 12 and 17 years old (M=14.45, SD=1.59), 1,836 males and 2,049 females, recruited from 39 secondary schools in the east of Spain. The Cuestionario de victimización juvenil mediante internet y/o teléfono móvil (hereinafter, Juvenile Online Victimization Questionnaire, JOV-Q, Montiel & Carbonell, 2012) was applied for the assessment of eight types of online victimization grouped in two major domains: sexual (sexual coercion, sexual pressure, online grooming by an adult, unwanted exposure to sexual content and violation of privacy); and nonsexual victimization (online harassment, happy slapping, pressure to obtain personal information). Sixty-one percent of adolescents reported online victimization during the last year. Online sexual victimization was reported by 39.5% of adolescents and nonsexual victimization by 53.4% of them, whereas 31% of youth reported having experienced online victimization in both domains. The highest prevalence rates were recorded for online harassment (50%), unwanted exposure to sexual content (24.4%), pressure to obtain personal information (18.4%) and online grooming by an adult (17.2%), and the lowest for sexual coercion (6.7%) and happy slapping (2.2%). Thirty-five percent of the adolescents were considered online polyvictims and most of them experienced victimization in both sexual and nonsexual domains (88%). This study illustrates that Spanish adolescents experience high levels of online victimization and that multiple online victimization appears to be the norm among cybervictims. Copyright © 2015 Elsevier Ltd. All rights reserved.
Paginas del estudiante de espanol (Study Pages for the Spanish Student)
ERIC Educational Resources Information Center
Carballo Picazo, Alfredo
1977-01-01
This Spanish lesson consists of an essay on the use of "usted" and "tu," followed by a series of exercises including questions on the text, vocabulary, grammar and the use of the subjunctive. (Text is in Spanish.) (CHK)
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2010-04-22
... rule consolidation process, FINRA recently made several changes to its financial responsibility rules... 9559 to conform BX's rules to recent changes to the rules of the Financial Industry Regulatory...' financial responsibilities and the rules concerning expedited hearings in light of changes made to the...
La Hispanidad en los Estados Unidos (Spanish Influence in the United States)
ERIC Educational Resources Information Center
Da Silva, Zenia Sacks
1975-01-01
This paper recounts a brief history of Spanish exploration in the territory of the United States and surveys Spanish influence in industry, agriculture, foods, architecture and vocabulary. (Text is in Spanish.) (CK)
Synchronous Computer-Mediated Dynamic Assessment: A Case Study of L2 Spanish Past Narration
ERIC Educational Resources Information Center
Darhower, Mark Anthony
2014-01-01
In this study, dynamic assessment is employed to help understand the developmental processes of two university Spanish learners as they produce a series of past narrations in a synchronous computer mediated environment. The assessments were conducted in six weekly one-hour chat sessions about various scenes of a Spanish language film. The analysis…
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2011-03-04
... Organizations; NASDAQ OMX BX; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Adopt New... adopt new Rule 4763 as a written policy or procedure to implement the amendments to Rules 200(g) and 201... Act Release No. 61595 (Feb. 26, 2010), 75 FR 11232 (Mar. 10, 2010) (``Adopting Release'') (amending...
Evaluation of "Guia para Dejar de Fumar," a self-help guide in Spanish to quit smoking.
Pérez-Stable, E J; Sabogal, F; Marín, G; Marín, B V; Otero-Sabogal, R
1991-01-01
Because of the absence of culturally appropriate self-help smoking cessation materials for Latinos, a new Spanish language cessation guide, "Guia para Dejar de Fumar," was developed and evaluated. It was distributed as part of a community-wide intervention to decrease the prevalence of smoking. The "Guia" is an attractive full-color booklet written in universal Spanish that uses simple text and numerous photographs. Motivation to quit smoking is emphasized, and graphic demonstrations of the adverse health effects of smoking are included. A menu of quitting and maintenance techniques is presented. A total of 431 smokers were identified for evaluation at approximately 3, 6, and 12 months after receiving the "Guia." Self-reported quit rates declined from 21.1 percent at 2.5 months to 13.7 percent at 14 months; 8.4 percent of the sample had a validated quit status by saliva cotinine test at 1 year. Persons older than 44 years were more likely to remain nonsmokers, but sex, education, acculturation score, and cigarettes smoked per day did not predict smoking cessation. The components of the "Guia" most mentioned by those who were surveyed were the graphic photographs, the health emphasis, and the overall format. The authors concluded that the "Guia" is an appropriate self-help smoking cessation booklet for Spanish-speaking Latinos in the United States. PMID:1910191
Spanish American Customs, Culture and Personality.
ERIC Educational Resources Information Center
Reindorp, Reginald C.
This textbook develops a cross-cultural portrait of Latin America. Four major sections are concerned with the cultural blueprint, historical and social foundations, the social structure, and intellectual and economic life. Subchapters include: (1) the rise of the Spanish people, (2) administration and jurisprudence, (3) the church, (4) the…
Nassif, Samih J; Wong, Kevin; Levi, Jessica R
2018-01-01
Evaluate the reading difficulty of Spanish patient education materials using the validated Índice Flesch-Szigriszt (INFLESZ) and Spanish Lexile Analyzer, and to identify relationships between English and Spanish readability formulas. Cross-sectional analysis. All otolaryngology-related patient education articles written in Spanish from the health libraries of the top 10 US News & World Report-ranked hospitals, top 10 Doximity-ranked otolaryngology residencies, the American Academy of Otolaryngology-Head and Neck Surgery website, and the US National Library of Medicine online section on ears, nose and throat were collected. Reading difficulty was assessed using the INFLESZ and Spanish Lexile Analyzer. Additional readability assessments included the traditional English tools: Flesch-Kincaid Grade Level, Flesch Reading Ease Score, and the Simple Measure of Gobbledygook score. A total of 497 articles were reviewed. The average INFLESZ score for all articles was 57.75, which is considered normal and requires the reading ability of a student who finished Escuela Secundaria Obligatoria or 10th grade equivalent in the United States. The average Spanish Lexile measure for all articles was 1062L, equivalent to a reading level between the 6th and 12th grade. English readability tools calculated a more difficult reading level compared to Spanish tools when performed on the same text. Current Spanish patient education materials in otolaryngology may be too difficult for the average Spanish-speaking reader to understand. Future improvements may be warranted to improve the readability of educational materials and increase health literacy. NA. Laryngoscope, 128:E21-E26, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.
Martín-Espinosa, Noelia; Díez-Fernández, Ana; Sánchez-López, Mairena; Rivero-Merino, Irene; Lucas-De La Cruz, Lidia; Solera-Martínez, Montserrat; Martínez-Vizcaíno, Vicente
2017-01-01
The prevalence of high blood pressure in children is increasing worldwide, largely, but not entirely, driven by the concurrent childhood obesity epidemic. The aims of this study were to examine the prevalence of prehypertension and hypertension in 4-to-6-year-old Spanish schoolchildren, and to evaluate the association between different blood pressure (BP) components with different adiposity indicators. Cross-sectional study including a sample of 1.604 schoolchildren aged 4-to-6-years belonging to 21 schools from the provinces of Ciudad Real and Cuenca, Spain. We measured height, weight, body mass index (BMI), fat mass percentage (%FM), triceps skinfold thickness (TST), waist circumference (WC), systolic and diastolic BP, mean arterial pressure and pulse pressure. The estimates of prevalence of prehypertension and hypertension were 12.3% and 18.2%, respectively. In both sexes, adiposity indicators were positively and significantly associated with all BP components (p<0.001), thus schoolchildren in the higher adiposity categories had significantly higher BP levels (p<0.001). Our results show a high prevalence of high blood pressure in Spanish children. Moreover, high levels of adiposity are associated with high blood pressure in early childhood, which support that it could be related to cardiovascular risk later in life.
Aldámiz-Echevarría, Luis; Llarena, Marta; Bueno, María A; Dalmau, Jaime; Vitoria, Isidro; Fernández-Marmiesse, Ana; Andrade, Fernando; Blasco, Javier; Alcalde, Carlos; Gil, David; García, María C; González-Lamuño, Domingo; Ruiz, Mónica; Ruiz, María A; Peña-Quintana, Luis; González, David; Sánchez-Valverde, Felix; Desviat, Lourdes R; Pérez, Belen; Couce, María L
2016-08-01
Phenylketonuria (PKU), the most common inborn error of amino acid metabolism, is caused by mutations in the phenylalanine-4-hydroxylase (PAH) gene. This study aimed to assess the genotype-phenotype correlation in the PKU Spanish population and the usefulness in establishing genotype-based predictions of BH4 responsiveness in our population. It involved the molecular characterization of 411 Spanish PKU patients: mild hyperphenylalaninemia non-treated (mild HPA-NT) (34%), mild HPA (8.8%), mild-moderate (20.7%) and classic (36.5%) PKU. BH4 responsiveness was evaluated using a 6R-BH4 loading test. We assessed genotype-phenotype associations and genotype-BH4 responsiveness in our population according to literature and classification of the mutations. The mutational spectrum analysis showed 116 distinct mutations, most missense (70.7%) and located in the catalytic domain (62.9%). The most prevalent mutations were c.1066-11G>A (9.7%), p.Val388Met (6.6%) and p.Arg261Gln (6.3%). Three novel mutations (c.61-13del9, p.Ile283Val and p.Gly148Val) were reported. Although good genotype-phenotype correlation was observed, there was no exact correlation for some genotypes. Among the patients monitored for the 6R-BH4 loading test: 102 were responders (87, carried either one or two BH4-responsive alleles) and 194 non-responders (50, had two non-responsive mutations). More discrepancies were observed in non-responders. Our data reveal a great genetic heterogeneity in our population. Genotype is quite a good predictor of phenotype and BH4 responsiveness, which is relevant for patient management, treatment and follow-up.
Park, Ji Hun; Kho, Min Chol; Oh, Hyun Cheol; Kim, Youn Chul; Yoon, Jung Joo; Lee, Yun Jung; Kang, Dae Gill; Lee, Ho Sub
2018-05-13
Renal ischemia-reperfusion injury (IRI), an important cause of acute kidney injury (AKI), causes increased renal tubular injury and microvascular inflammation. 1,[Formula: see text]2,[Formula: see text]3,[Formula: see text]4,[Formula: see text]6-penta-O-galloyl-[Formula: see text]-D-glucose (PGG) from Galla rhois has anticancer, anti-oxidation and angiogenesis effects. We examined protective effects of PGG on IRI-induced acute AKI. Clamping both renal arteries for 45[Formula: see text]min induced isechemia and then reperfusion. Treatment with PGG (10[Formula: see text]mg/kg/day and 50[Formula: see text]mg/kg/day for four days) significantly ameliorated urine volume, urine osmolality, creatinine clearance (Ccr) and blood urea nitrogen (BUN). In addition, PGG increased aquaporine 1/2/3, Na[Formula: see text]-K[Formula: see text]-ATPase and urea transporter (UT-B) and decreased ICAM-1, MCP-1, and HMGB-1 expression. In this histopathologic study, PGG improved glomerular and tubular damage. Immunohistochemistry results showed that PGG increased aquaporine 1/2, and Na[Formula: see text]-K[Formula: see text] ATPase and decreased ICAM-1 expression. These findings suggest that PGG ameliorates tubular injury including tubular dysfunction and microvascular inflammation in IRI-induced AKI rats.
Validating a Spanish Developmental Spelling Test.
ERIC Educational Resources Information Center
Ferroli, Lou; Krajenta, Marilyn
The creation and validation of a Spanish version of an English developmental spelling test (DST) is described. An introductory section reviews related literature on the rationale for and construction of DSTs, spelling development in the early grades, and Spanish-English bilingual education. Differences between the English and Spanish test versions…
ERIC Educational Resources Information Center
Wijekumar, Kausalai; Meyer, Bonnie J. F.; Lei, Puiwa
2014-01-01
Reading in the content areas of science, social studies, and current events is a difficult task that is even more elusive to Spanish speaking English language learners. There is a huge increase in children transitioning from their L1 (e.g., Spanish) to L2 (e.g., English) in classrooms across the US. These ELs face challenges due to a lack of…
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Solution of the symmetric eigenproblem AX=lambda BX by delayed division
NASA Technical Reports Server (NTRS)
Thurston, G. A.; Bains, N. J. C.
1986-01-01
Delayed division is an iterative method for solving the linear eigenvalue problem AX = lambda BX for a limited number of small eigenvalues and their corresponding eigenvectors. The distinctive feature of the method is the reduction of the problem to an approximate triangular form by systematically dropping quadratic terms in the eigenvalue lambda. The report describes the pivoting strategy in the reduction and the method for preserving symmetry in submatrices at each reduction step. Along with the approximate triangular reduction, the report extends some techniques used in the method of inverse subspace iteration. Examples are included for problems of varying complexity.
Development and Validation of the Spanish Numeracy Understanding in Medicine Instrument.
Jacobs, Elizabeth A; Walker, Cindy M; Miller, Tamara; Fletcher, Kathlyn E; Ganschow, Pamela S; Imbert, Diana; O'Connell, Maria; Neuner, Joan M; Schapira, Marilyn M
2016-11-01
The Spanish-speaking population in the U.S. is large and growing and is known to have lower health literacy than the English-speaking population. Less is known about the health numeracy of this population due to a lack of health numeracy measures in Spanish. we aimed to develop and validate a short and easy to use measure of health numeracy for Spanish-speaking adults: the Spanish Numeracy Understanding in Medicine Instrument (Spanish-NUMi). Items were generated based on qualitative studies in English- and Spanish-speaking adults and translated into Spanish using a group translation and consensus process. Candidate items for the Spanish NUMi were selected from an eight-item validated English Short NUMi. Differential Item Functioning (DIF) was conducted to evaluate equivalence between English and Spanish items. Cronbach's alpha was computed as a measure of reliability and a Pearson's correlation was used to evaluate the association between test scores and the Spanish Test of Functional Health Literacy (S-TOFHLA) and education level. Two-hundred and thirty-two Spanish-speaking Chicago residents were included in the study. The study population was diverse in age, gender, and level of education and 70 % reported Mexico as their country of origin. Two items of the English eight-item Short NUMi demonstrated DIF and were dropped. The resulting six-item test had a Cronbach's alpha of 0.72, a range of difficulty using classical test statistics (percent correct: 0.48 to 0.86), and adequate discrimination (item-total score correlation: 0.34-0.49). Scores were positively correlated with print literacy as measured by the S- TOFHLA (r = 0.67; p < 0.001) and varied as predicted across grade level; mean scores for up to eighth grade, ninth through twelfth grade, and some college experience or more, respectively, were 2.48 (SD ± 1.64), 4.15 (SD ± 1.45), and 4.82 (SD ± 0.37). The Spanish NUMi is a reliable and valid measure of important numerical concepts
Measuring Disparities: Bias in the SF-36v2 among Spanish-speaking Medical Patients
Sudano, Joseph J.; Perzynski, Adam; Love, Thomas E.; Lewis, Steven A.; Murray, Patrick M.; Huber, Gail; Ruo, Bernice; Baker, David W.
2011-01-01
Background Many national surveys have found substantial differences in self-reported overall health (SROH) between Spanish-speaking Hispanics and other racial/ethnic groups. However, because cultural and language differences may create measurement bias, it is unclear whether observed differences in SROH reflect true differences in health. Objectives This study uses a cross-sectional survey to investigate psychometric properties of the SF-36v2 for subjects across four racial/ethnic and language groups. Multi-group latent variable modeling was used to test increasingly stringent criteria for measurement equivalence. Subjects Our sample (N = 1281) included 383 non-Hispanic whites, 368 non-Hispanic blacks, 206 Hispanics interviewed in English and 324 Hispanics interviewed in Spanish recruited from outpatient medical clinics in two large urban areas. Results We found weak factorial invariance across the four groups. However, there was no strong factorial invariance. The overall fit of the model was substantially worse (change in CFI > .02, RMSEA change > .003) after requiring equal intercepts across all groups. Further comparisons established that the equality constraints on the intercepts for Spanish-speaking Hispanics were responsible for the decrement to model fit. Conclusions Observed differences between SF-36v2 scores for Spanish speaking Hispanics are systematically biased relative to the other three groups. The lack of strong invariance suggests the need for caution when comparing SF-36v2 mean scores of Spanish-speaking Hispanics with those of other groups. However, measurement equivalence testing for this study supports correlational or multivariate latent variable analyses of SF-36v2 responses across all four subgroups, since these analyses require only weak factorial invariance. PMID:21430580
Graphic Arts. A Bilingual Text = Artes Graficas. Un Texto Bilingue.
ERIC Educational Resources Information Center
Los Angeles Unified School District, CA. Div. of Career and Continuing Education.
This bilingual instructional text, one in a series of six texts covering various vocational and technical topics, provides secondary level English and Spanish instruction in graphic arts. Addressed in the individual sections are basic graphic arts (composition, stone and press work, offset printing, silk screen, and photography) and allied graphic…
Band gap bowing and crossing of BxGa1-xN alloy investigated by hybrid functional method
NASA Astrophysics Data System (ADS)
Jiaping, Jiang; Yanqin, Gai; Gang, Tang
2016-02-01
The electronic properties of zinc-blende BxGa1-xN alloys are comparatively investigated by employing both the Perdewe-Burkee-Ernzerhof generalized-gradient approximation (PBE-GGA) and the Heyd-Scuseria-Ernzerhof screened hybrid functional methods (HSE06). HSE06 reproduced much closer ground-state properties to experiments. Large and composition-dependent bowing parameters bγ for the direct band gaps were obtained from both PBE and HSE06. The crossover composition where alloy switches from direct to indirect was predicted to occur at very similar x from PBE and HSE06. We can obtain direct gap BxGa1-xN with a gap value much larger than that of GaN by alloying x < 0.557 boron into GaN. Project supported by the Fundamental Research Funds for the Central Universities (No. 2010LKWL03), the Special Fund for Theoretical Physics (No. 11047130), and the National Natural Science Foundation of China (No. 11104345).
2010-01-01
Background Hispanics comprise the largest ethnic minority group in the United States. Previous work with the Spanish Modified Dental Anxiety Scale (MDAS) yielded good validity, but lower test-retest reliability. We report the performance of the Spanish MDAS in a new sample, as well as the performance of the Spanish Revised Dental Beliefs Survey (R-DBS). Methods One hundred sixty two Spanish-speaking adults attending Spanish-language church services or an Hispanic cultural festival completed questionnaires containing the Spanish MDAS, Spanish R-DBS, and dental attendance questions, and underwent a brief oral examination. Church attendees completed the questionnaire a second time, for test-retest purposes. Results The Spanish MDAS and R-DBS were completed by 156 and 136 adults, respectively. The test-retest reliability of the Spanish MDAS was 0.83 (95% CI = 0.60-0.92). The internal reliability of the Spanish R-DBS was 0.96 (95% CI = 0.94-0.97), and the test-retest reliability was 0.86 (95% CI = 0.64-0.94). The two measures were significantly correlated (Spearman's rho = 0.38, p < 0.001). Participants who do not currently go to a dentist had significantly higher MDAS scores (t = 3.40, df = 106, p = 0.003) as well as significantly higher R-DBS scores (t = 2.21, df = 131, p = 0.029). Participants whose most recent dental visit was for pain or a problem, rather than for a check-up, scored significantly higher on both the MDAS (t = 3.00, df = 106, p = 0.003) and the R-DBS (t = 2.85, df = 92, p = 0.005). Those with high dental fear (MDAS score 19 or greater) were significantly more likely to have severe caries (Chi square = 6.644, df = 2, p = 0.036). Higher scores on the R-DBS were significantly related to having more missing teeth (Spearman's rho = 0.23, p = 0.009). Conclusion In this sample, the test-retest reliability of the Spanish MDAS was higher. The significant relationships between dental attendance and questionnaire scores, as well as the difference in caries
Coolidge, Trilby; Hillstead, M Blake; Farjo, Nadia; Weinstein, Philip; Coldwell, Susan E
2010-05-13
Hispanics comprise the largest ethnic minority group in the United States. Previous work with the Spanish Modified Dental Anxiety Scale (MDAS) yielded good validity, but lower test-retest reliability. We report the performance of the Spanish MDAS in a new sample, as well as the performance of the Spanish Revised Dental Beliefs Survey (R-DBS). One hundred sixty two Spanish-speaking adults attending Spanish-language church services or an Hispanic cultural festival completed questionnaires containing the Spanish MDAS, Spanish R-DBS, and dental attendance questions, and underwent a brief oral examination. Church attendees completed the questionnaire a second time, for test-retest purposes. The Spanish MDAS and R-DBS were completed by 156 and 136 adults, respectively. The test-retest reliability of the Spanish MDAS was 0.83 (95% CI = 0.60-0.92). The internal reliability of the Spanish R-DBS was 0.96 (95% CI = 0.94-0.97), and the test-retest reliability was 0.86 (95% CI = 0.64-0.94). The two measures were significantly correlated (Spearman's rho = 0.38, p < 0.001). Participants who do not currently go to a dentist had significantly higher MDAS scores (t = 3.40, df = 106, p = 0.003) as well as significantly higher R-DBS scores (t = 2.21, df = 131, p = 0.029). Participants whose most recent dental visit was for pain or a problem, rather than for a check-up, scored significantly higher on both the MDAS (t = 3.00, df = 106, p = 0.003) and the R-DBS (t = 2.85, df = 92, p = 0.005). Those with high dental fear (MDAS score 19 or greater) were significantly more likely to have severe caries (Chi square = 6.644, df = 2, p = 0.036). Higher scores on the R-DBS were significantly related to having more missing teeth (Spearman's rho = 0.23, p = 0.009). In this sample, the test-retest reliability of the Spanish MDAS was higher. The significant relationships between dental attendance and questionnaire scores, as well as the difference in caries severity seen in those with high fear, add
The L2 Acquisition of Buenos Aires Spanish Intonation during a Study Abroad Semester
ERIC Educational Resources Information Center
Thornberry, Philip A.
2014-01-01
The present longitudinal study describes and categorizes the primary changes in L2 Spanish intonation over time by 11 learners studying abroad in Buenos Aires, Argentina for one academic semester. Via the autosegmental metrical model of analysis, this dissertation classifies intonational contours for absolute interrogatives and declarative…
Vallejo, Miguel A.; Vallejo-Slocker, Laura; Fernández-Abascal, Enrique G.; Mañanes, Guillermo
2018-01-01
Objective: Stress perception depends on cultural and social aspects that vary from one country to another. One of the most widely disseminated methods of assessing psychological stress is the Perceived Stress Scale (PSS-4). Therefore, in order to identify these factors and their impact on mental health, the present study compares the PSS-4 results among three European countries (Great Britain, France and Spain). This study focuses on PSS-4 results within a Spanish sample to determine: (1) normative data, reliability and validity of PSS-4 in a Spanish sample and (2) how stress perception changes depending on cultural and social factors. Methods: The data were obtained from a website representing a service of a smoking cessation program, the study represented a service that was open to all individuals. The number of participants were 37,451. They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R). Results: The PSS-4 scores could differentiate between relevant sociodemographic variables (such as sex, age, nationality, marital status, education, parental status, employment status, and income class). The PSS-4 scores showed a positive correlation with the SCL 90-R anxiety and depression scales. The normed values for interpreting the PSS-4 scores are presented. The PSS-4 showed adequate internal consistency and reliability. Conclusions: The PSS-4 is a useful instrument for assessing stress perception levels in the general population in different countries. Its internal consistency is sufficient for a 4-item scale. PMID:29434563
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Negative differential resistance and switch behavior of T-BxNy (x, y = 5, 6, 11) molecular junctions
NASA Astrophysics Data System (ADS)
Wang, Shi-Liang; Yang, Chuan-Lu; Wang, Mei-Shan; Ma, Xiao-Guang; Xin, Jian-Guo
2017-05-01
The electronic transport properties of T-BxNy (x, y = 5, 6, 11) molecular junction are investigated based on first-principle density functional theory and non-equilibrium Green's function method. Strong negative differential resistance (NDR) behavior is observed for T-B5N6 molecule under negative and positive bias voltages, with an obvious switch effect for T-B6N5. However, only small NDR is shown for the complex of the two molecules. The projected device density of states, the spatial distribution of molecular orbitals, and the effect of transmission spectra under various bias voltages on the electronic transport properties are analyzed. The obvious effect of bias voltage on the changes in the electronic distribution of frontier molecular orbitals is responsible for the NDR or switch behavior. Therefore, different functional molecular devices can be obtained with different structures of T-BxNy.
Palés, Jorge; Gual, Arcadi; Escanero, Jesús; Tomás, Inmaculada; Rodríguez-de Castro, Felipe; Elorduy, Marta; Virumbrales, Montserrat; Rodríguez, Gerardo; Arce, Víctor
2015-06-08
The purpose of this study was to investigate student's perceptions of Educational Climate (EC) in Spanish medical schools, comparing various aspects of EC between the 2nd (preclinical) and the 4th (clinical) years to detect strengths and weaknesses in the on-going curricular reform. This study utilized a cross-sectional design and employed the Spanish version of the "Dundee Ready Education Environment Measure" (DREEM). The survey involved 894 2nd year students and 619 4th year students from five Spanish medical schools. The global average score of 2nd year students from the five medical schools was found to be significantly higher (116.2±24.9, 58.2% of maximum score) than that observed in 4th year students (104.8±29.5, 52.4% of maximum score). When the results in each medical school were analysed separately, the scores obtained in the 2nd year were almost always significantly higher than in the 4th year for all medical schools, in both the global scales and the different subscales. The perception of the EC by 2nd and 4th year students from five Spanish medical schools is more positive than negative although it is significantly lower in the 4th year. In both years, although more evident in the 4th year, students point out the existence of several important "problematic educational areas" associated with the persistence of traditional curricula and teaching methodologies. Our findings of this study should lead medical schools to make a serious reflection and drive the implementation of the necessary changes required to improve teaching, especially during the clinical period.
Gual, Arcadi; Escaneroi, Jesus; Tomás, Inmaculada; Rodríguez de Castro, Felipe; Elorudy, Marta; Virumbrales, Montserrat; Rodríguez, Gerardo; Arce, Victor
2015-01-01
Objectives The purpose of this study was to investigate student's perceptions of Educational Climate (EC) in Spanish medical schools, comparing various aspects of EC between the 2nd (preclinical) and the 4th (clinical) years to detect strengths and weaknesses in the on-going curricular reform. Methods This study utilized a cross-sectional design and employed the Spanish version of the "Dundee Ready Education Environment Measure" (DREEM). The survey involved 894 2nd year students and 619 4th year students from five Spanish medical schools. Results The global average score of 2nd year students from the five medical schools was found to be significantly higher (116.2±24.9, 58.2% of maximum score) than that observed in 4th year students (104.8±29.5, 52.4% of maximum score). When the results in each medical school were analysed separately, the scores obtained in the 2nd year were almost always significantly higher than in the 4th year for all medical schools, in both the global scales and the different subscales. Conclusions The perception of the EC by 2nd and 4th year students from five Spanish medical schools is more positive than negative although it is significantly lower in the 4th year. In both years, although more evident in the 4th year, students point out the existence of several important "problematic educational areas" associated with the persistence of traditional curricula and teaching methodologies. Our findings of this study should lead medical schools to make a serious reflection and drive the implementation of the necessary changes required to improve teaching, especially during the clinical period. PMID:26057355
ERIC Educational Resources Information Center
Wright, Adrienne C.
2017-01-01
Spanish-speaking parents choose to enroll their children in either an English only or English-Spanish dual immersion program when presented with both choices. This ethnographic study explored parent's perceptions of the purpose, advantages, and disadvantages of learning in school in English only or in a dual English-Spanish. Through focus group…
Crespo, Patricia; Jiménez, Juan E; Rodríguez, Cristina; Baker, Doris; Park, Yonghan
2018-03-09
The present study compares the patterns of growth of beginning reading skills (i.e., phonemic awareness, phonics, fluency, vocabulary and comprehension) of Spanish speaking monolingual students who received a Tier 2 reading intervention with students who did not receive the intervention. All the students in grades K-2 were screened at the beginning of the year to confirm their risk status. A quasi-experimental longitudinal design was used: the treatment group received a supplemental program in small groups of 3 to 5 students, for 30 minutes daily from November to June. The control group did not receive it. All students were assessed three times during the academic year. A hierarchical linear growth modeling was conducted and differences on growth rate were found in vocabulary in kindergarten (p < .001; variance explained = 77.0%), phonemic awareness in kindergarten (p < .001; variance explained = 43.7%) and first grade (p < .01; variance explained = 15.2%), and finally we also find significant growth differences for second grade in oral reading fluency (p < .05; variance explained = 15.1%) and retell task (p < .05; variance explained = 14.5%). Children at risk for reading disabilities in Spanish can improve their skills when they receive explicit instruction in the context of Response to Intervention (RtI). Findings are discussed for each skill in the context of implementing a Tier 2 small group intervention within an RtI approach. Implications for practice in the Spanish educational context are also discussed for children who are struggling with reading.
Adult Second Language Learning of Spanish Vowels
ERIC Educational Resources Information Center
Cobb, Katherine; Simonet, Miquel
2015-01-01
The present study reports on the findings of a cross-sectional acoustic study of the production of Spanish vowels by three different groups of speakers: 1) native Spanish speakers; 2) native English intermediate learners of Spanish; and 3) native English advanced learners of Spanish. In particular, we examined the production of the five Spanish…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-22
... business or personal relationship of the compensation consultant, legal counsel or other adviser with a..., legal counsel or other adviser; and (vi) any business or personal relationship of the compensation... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-68641; File No. SR-BX-2012-063] Self-Regulatory...
NASA Astrophysics Data System (ADS)
Fleet, M. E.; Macrae, N. D.
1987-03-01
The experimental distribution coefficient for Ni/ Fe exchange between olivine and monosulfide (KD3) is 35.6±1.1 at 1385° C, f_{{text{O}}_{text{2}} } = 10^{ - 8.87} ,f_{{text{S}}_{text{2}} } = 10^{ - 1.02} , and olivine of composition Fo96 to Fo92. These are the physicochemical conditions appropriate to hypothesized sulfur-saturated komatiite magma. The present experiments equilibrated natural olivine grains with sulfide-oxide liquid in the presence of a (Mg, Fe)-alumino-silicate melt. By a variety of different experimental procedures, K D3 is shown to be essentially constant at about 30 to 35 in the temperature range 900 to 1400° C, for olivine of composition Fo97 to FoO, monosulfide composition with up to 70 mol. % NiS, and a wide range of f_{{text{O}}_{text{2}} } and f_{{text{S}}_{text{2}} }.
Industrial Crafts. A Bilingual Text = Trabajos Manuales Industriales. Un Texto Bilingue.
ERIC Educational Resources Information Center
Los Angeles Unified School District, CA. Div. of Career and Continuing Education.
This bilingual instructional text, one in a series of six texts covering various vocational and technical topics, provides secondary level English and Spanish instruction in industrial crafts. Addressed in the individual units are the following topics: plastics; laminating acrylic plastic; thermoforming plastics; sawing, shaping, and finishing…
Vázquez, Gustavo Héctor; Romero, Ester; Fabregues, Fernando; Pies, Ronald; Ghaemi, Nassir; Mota-Castillo, Manuel
2010-01-01
Bipolar disorder is commonly misdiagnosed, perhaps more so in Latin American and Spanish-speaking populations than in the United States. The Bipolar Spectrum Diagnostic Scale (BSDS) is a 19-item screening instrument designed to assist in screening for all types of bipolar disorder. The authors investigated the sensitivity of a Spanish-language version of the BSDS in a cohort of 65 outpatients with a diagnosis of bipolar disorder, based on a semi-structured interview and Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision criteria. To determine specificity, we assessed a control group of 36 outpatients with diagnosis of unipolar major depressive disorder. The overall sensitivity of the BSDS Spanish version with bipolar disorders types I, II, and NOS was 0.70, which was slightly lower than the sensitivity in the study using the English version of the BSDS (0.76). The specificity was 0.89. When the threshold was decreased from 13 to 12, the sensitivity of the Spanish BSDS increased to 0.76 and specificity dropped to 0.81. The Spanish version of the BSDS is promising as a screening instrument in Spanish-speaking populations. Copyright 2010 Elsevier Inc. All rights reserved.
Apuntes sobre Latinismos en Espanol (Notes on Latinisms in Spanish)
ERIC Educational Resources Information Center
Perez B., L. A.
1977-01-01
Several Latinisms appear in Latin American Spanish, which would logically be farther from its Latin roots than Spanish in Spain. The existence of these elements and their importance as linguistic facts is analyzed here. Four words are treated: "Cliente,""cuadrar,""cuarto" and "rabula." (Text is in Spanish.) (CHK)
A Practical Spanish Grammar for Border Patrol Officers.
ERIC Educational Resources Information Center
Border Patrol Academy, El Paso, TX.
Designed to be used in the Spanish training program for probationary officers at the Border Patrol Academy in El Paso, Texas, this revised 21-lesson traditional grammar text includes special features that make it pertinent to the job of a patrol inspector in the Mexican border area. An extensive appendix is comprised of exercise translations,…
Spanish Americans in North Dakota, 1980: A Statistical Portrait. Report Series No. 7.
ERIC Educational Resources Information Center
Daul, Jennifer; And Others
Demographic and economic characteristics of Spanish Americans in North Dakota in 1980 are presented, using data from the Bureau of the Census. Statistics show 3,902 Spanish Americans were living in North Dakota (0.6% of the state's population): 59.4% were Mexican; 6.3% Puerto Rican, 1.5% Cuban, and 32.8% of other Spanish descent, with more males…
Martín-Espinosa, Noelia; Díez-Fernández, Ana; Sánchez-López, Mairena; Rivero-Merino, Irene; Lucas-De La Cruz, Lidia; Solera-Martínez, Montserrat; Martínez-Vizcaíno, Vicente
2017-01-01
Background The prevalence of high blood pressure in children is increasing worldwide, largely, but not entirely, driven by the concurrent childhood obesity epidemic. The aims of this study were to examine the prevalence of prehypertension and hypertension in 4-to-6-year-old Spanish schoolchildren, and to evaluate the association between different blood pressure (BP) components with different adiposity indicators. Methods Cross-sectional study including a sample of 1.604 schoolchildren aged 4-to-6-years belonging to 21 schools from the provinces of Ciudad Real and Cuenca, Spain. We measured height, weight, body mass index (BMI), fat mass percentage (%FM), triceps skinfold thickness (TST), waist circumference (WC), systolic and diastolic BP, mean arterial pressure and pulse pressure. Results The estimates of prevalence of prehypertension and hypertension were 12.3% and 18.2%, respectively. In both sexes, adiposity indicators were positively and significantly associated with all BP components (p<0.001), thus schoolchildren in the higher adiposity categories had significantly higher BP levels (p<0.001). Conclusions Our results show a high prevalence of high blood pressure in Spanish children. Moreover, high levels of adiposity are associated with high blood pressure in early childhood, which support that it could be related to cardiovascular risk later in life. PMID:28141860
Driver Education, English-Spanish. Learning Achievement Packages. Revised Edition.
ERIC Educational Resources Information Center
Rendon, Rene
This text contains three suggested driver education curriculum units and is intended for use in a bilingual education setting. Each unit is in Spanish and English. The three units are: (1) "Procedures in Driving," (2) "Car Maintenance," and (3) "Tires." Each unit contains information for the teacher, explanations and…
Spanish version of Colquitt's Organizational Justice Scale.
Díaz-Gracia, Liliana; Barbaranelli, Claudio; Moreno-Jiménez, Bernardo
2014-01-01
Organizational justice (OJ) is an important predictor of different work attitudes and behaviors. Colquitt's Organizational Justice Scale (COJS) was designed to assess employees' perceptions of fairness. This scale has four dimensions: distributive, procedural, informational, and interpersonal justice. The objective of this study is to validate it in a Spanish sample. The scale was administered to 460 Spanish employees from the service sector. 40.4% were men and 59.6% women. The Confirmatory Factor Analysis (CFA) supported the four dimensions structure for Spanish version of COJS. This model showed a better fit to data that the others models tested. Cronbach's alpha obtained for subscales ranged between .88 and .95. Correlations of the Spanish version of COJS with measures of incivility and job satisfaction were statistically significant and had a moderate to high magnitude, indicating a reasonable degree of construct validity. The Spanish version of COJS has adequate psychometric properties and may be of value in assessing OJ in Spanish setting.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-08
... business on the Exchange. The proposed change will have no effect on the assessment of fees for current BOX... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change... (``Commission'') the proposed rule change as described in Items I and II below, which Items have been prepared...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-09
..., dated September 28, 2010; Michael R. Trocchio, Bingham McCutchen LLP, on behalf of Pink OTC Markets Inc... Listing Market on the Exchange March 3, 2011. On August 20, 2010, NASDAQ OMX BX, Inc. (the ``Exchange... change to create a listing market on the Exchange. The proposed rule change was published for comment in...
Development and Validation of the Marijuana Motives Measure Short Form.
Mezquita, Laura; Ruiz-Valero, Lucía; Martínez-Gómez, Naiara; Ibáñez, Manuel I; Ortet, Generós
2018-01-15
Marijuana motives are a proximal variable to marijuana use. This research aimed to adapt and validate the short form of the Marijuana Motives Measure (MMM; Simons, Correia, Carey, y Borsari, 1998), the MMM SF, in Spanish. The sample comprised 232 participants (mean age = 25.11 (7.58), 50.43% males) who had tried marijuana at least once in their lifetime. Item and Rasch analyses were performed to choose the final pool of 15 items. Confirmatory Factor Analysis (CFA) showed an adequate 5-factor structure (S-BX2(80) = 121.30, p = .002; NNFI = .944; CFI = .958; IFI = .959; MFI = .915; RMSEA = .047(0.029, 0.063); AIC = -38.70), and the multi-group CFA between males and females showed acceptable fit indices (S-BX2(160) = 230.01, p = .000; NNFI = .900; CFI = .924; IFI = .927; MFI = .860; RMSEA = .062(.043, .078); AIC = -89.99). The questionnaire indicated metric (S-BX2diff (15) = 13.61, p = .556)), scalar (S-BX2diff (15) = 23.15, p = .081)) and error measurement invariance (S-BX2diff (15) = 8.65, p = .895)) between gender groups. The internal consistencies and ordinal omega of the scales were between .79 and .90. In the regression analysis, enhancement, coping and low conformity motives predicted frequency and quantity of marijuana smoked. The best predictor of frequency and quantity consumed during the heaviest smoking period was enhancement, while coping and, to a lesser extent, low conformity, were the only predictors of cannabis-related problems when marijuana frequency and quantity were controlled for. The MMM SF shows adequate psychometric properties and is a suitable instrument to assess marijuana motives, especially during time-limited sessions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lindenmeier, Clark W.; Serne, R. Jeffrey; Bjornstad, Bruce N.
2003-09-11
This report summarizes data collected from samples in borehole 299-E33-338 (C3391). Borehole 299-E33-338 was drilled for two purposes. One purpose was for installation of a RCRA ground-water monitoring well and the other was to characterize the in situ soils and background porewater chemistry near WMA B-BX-BY that have been largely uncontaminated by tank farm and crib and trench discharge operations. This borehole was drilled just outside the southeast fence line of the B tank farm. The borehole was drilled between July 23 and August 8, 2001 to a total depth of 80.05 m (275.75 ft) bgs using the cable-tool methodmore » (Horton 2002). The water table was contacted at 77.5 m (254.2 ft) bgs and the top of basalt at 82.6 m (271 ft) bgs. Samples to the top of basalt were collected via a drive barrel/splitspoon, before switching to a hard tool to drill 5 feet into the basalt. Nearly continuous core was obtained down to a depth of ~78.6 m (258 ft) bgs. Two hundred and two 2-ft long by 4-in diameter cores were retrieved, which accounts for ~75% the total length of the borehole. Each 2-ft splitspoon contained two 1-ft lexan-lined core segments. The lithology of this borehole was summarized onto a field geologist's log by a CH2M HILL Hanford Group, Inc. geologist (L. D. Walker); subsequently visual inspection of the cores was performed in the laboratory by K. A. Lindsey (Kennedy/Jenks), K. D. Reynolds (Duratek), and B. N. Bjornstad (Pacific Northwest National Laboratory), who also collected 24 samples for paleomagnetic analysis. Subsamples were taken from all 102 cores for moisture content (Table B.1). In addition, 21 core subsamples were collected from a depth of geological interest for mineralogical and geochemical analysis. Data from these samples allow for comparison of uncontaminated versus contaminated soils to better understand the contributions of tank wastes and other wastewaters on the vadose zone in and around WMA B-BX-BY.« less
ERIC Educational Resources Information Center
Martínez, Ramón Antonio; Durán, Leah; Hikida, Michiko
2017-01-01
This article explores the interactional co-construction of identities among two first-grade students learning Spanish as a third language in a Spanish-English dual language classroom. Drawing on ethnographic and interactional data, the article focuses on a single interaction between these two "Spanish learners" and two of their…
2010-01-01
Background The Pain Self-Perception Scale (PSPS) is a 24-item questionnaire used to assess mental defeat in chronic pain patients. The aim of this study was to develop a Spanish language version of the PSPS (PSPS-Spanish), to assess the instrument's psychometric properties in a sample of patients with fibromyalgia and to confirm a possible overlapping between mental defeat and pain catastrophizing. Methods The PSPS was translated into Spanish by three bilingual content and linguistic experts, and then back-translated into English to assess for equivalence. The final Spanish version was administered, along with the Hospital Anxiety Depression Scale (HADS), Pain Visual Analogue Scale (PVAS), Pain Catastrophizing Scale (PCS) and Fibromyalgia Impact Questionnaire (FIQ), to 250 Spanish patients with fibromyalgia. Results PSPS-Spanish was found to have high internal consistency (Cronbach's α = 0.90 and the item-total r correlation coefficients ranged between 0.68 and 0.86). Principal components analysis revealed a one-factor structure which explained 61.4% of the variance. The test-retest correlation assessed with the intraclass correlation coefficient, over a 1-2 weeks interval, was 0.78. The total PSPS score was significantly correlated with all the questionnaires assessed (HADS, PVAS, PCS, and FIQ). Conclusions The Spanish version of the PSPS appears to be a valid tool in assessing mental defeat in patients with fibromyalgia. In patients with fibromyalgia and Post-Traumatic Stress Disorder (PTSD), PSPS-Spanish correlates more intensely with FIQ than in patients without PTSD. Mental defeat seems to be a psychological construct different to pain catastrophizing. PMID:21050485
ERIC Educational Resources Information Center
Taylor, Jose G., Comp.
Citing 123 books published between 1960 and 1977, this bibliography is divided into 3 main categories: (1) books with Spanish and English text, (2) translations of books also available in English, and (3) recommended books in Spanish. The first two sections concentrate on books for use in grades K-3. The final section includes books for older…
ERIC Educational Resources Information Center
Kobeck, Ashley Brianne
2013-01-01
Considering the recent increase in Spanish use in the United States, particularly as reflected in the media, beginning Spanish students are entering their classrooms with knowledge of phrases such as "hasta la vista" and "numero uno," regardless of their amount of previous formal Spanish study. The present research focuses on…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-13
... share executed for BTFY orders that execute at the New York Stock Exchange (``NYSE''), but NYSE charges... book for available shares only if so instructed by the entering firm and are thereafter routed out to... un-executed after routing, they are posted to the BX book and do not thereafter route out. The BTFY...
Spanish Language Health Materials: A Selective Bibliography.
ERIC Educational Resources Information Center
Trujillo, Roberto G., Ed.; And Others
This selected bibliography, compiled from recommendations by practicing librarians providing service to Spanish-speaking communities, includes Spanish and bilingual Spanish/English materials dealing with health. The topic is broadly defined to include any conditions which affect a person's well-being, and includes alcohol and drugs, consumer…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-24
... below $1. For these securities, BX currently charges members accessing liquidity a fee equal to 0.1% (10 basis points) of the total transaction cost and provides no credit to members providing liquidity. Under... transaction cost, and members providing liquidity will be provided a credit equal to 0.25% (25 basis points...
The Acquisition of Differential Object Marking in L2 Spanish Learners
ERIC Educational Resources Information Center
Martoccio, Alyssa Marie
2012-01-01
This dissertation tests a grammatical structure, differential object marking (DOM), which is particularly difficult for L2 learners to acquire. DOM is a phenomenon in which some direct objects are morphologically marked to distinguish them from subjects (Comrie, 1979). In Spanish, animate and specific direct objects are marked with the preposition…
Satisfaction with provider communication among Spanish-speaking Medicaid enrollees.
Mosen, David M; Carlson, Matthew J; Morales, Leo S; Hanes, Pamela P
2004-01-01
To determine if differences between English- and Spanish-speaking parents in ratings of their children's health care can be explained by need for interpretive services. Using the Consumer Assessment of Health Plans Survey-Child-Survey (CAHPS), reports about provider communication were compared among 3 groups of parents enrolled in a Medicaid managed care health plan: 1) English speakers, 2) Spanish speakers with no self-reported need for interpretive services, and 3) Spanish speakers with self-reported need for interpretive services. Parents were asked to report how well their providers 1) listened carefully to what was being said, 2) explained things in a way that could be understood, 3) respected their comments and concerns, and 4) spent enough time during medical encounters. Multivariate logistic regression was used to compare the ratings of each of the 3 groups while controlling for child's gender, parent's gender, parent's educational attainment, child's health status, and survey year. Spanish-speaking parents in need of interpretive services were less likely to report that providers spent enough time with their children (odds ratio = 0.34, 95% confidence interval = 0.17-0.68) compared to English-speaking parents. There was no statistically significant difference found between Spanish-speaking parents with no need of interpretive services and English-speaking parents. Among Spanish- versus English-speaking parents, differences in ratings of whether providers spent enough time with children during medical encounters appear to be explained, in part, by need for interpretive services. No other differences in ratings of provider communication were found.
Satisfaction With Communication in Primary Care for Spanish-Speaking and English-Speaking Parents.
Flower, Kori B; Skinner, Asheley C; Yin, H Shonna; Rothman, Russell L; Sanders, Lee M; Delamater, Alan; Perrin, Eliana M
Effective communication with primary care physicians is important yet incompletely understood for Spanish-speaking parents. We predicted lower satisfaction among Spanish-speaking compared to English-speaking Latino and non-Latino parents. Cross-sectional analysis at 2-month well visits within the Greenlight study at 4 pediatric resident clinics. Parents reported satisfaction with 14 physician communication items using the validated Communication Assessment Tool (CAT). High satisfaction was defined as "excellent" on each CAT item. Mean estimations compared satisfaction for communication items among Spanish- and English-speaking Latinos and non-Latinos. We used generalized linear regression modeling, adjusted for parent age, education, income, and clinic site. Among Spanish-speaking parents, we compared visits conducted in Spanish with and without an interpreter, and in English. Compared to English-speaking Latino (n = 127) and non-Latino parents (n = 432), fewer Spanish-speaking parents (n = 303) reported satisfaction with 14 communication items. No significant differences were found between English-speaking Latinos and non-Latinos. Greatest differences were found in the use of a greeting that made the parent comfortable (59.4% of Spanish-speaking Latinos endorsing "excellent" vs 77.5% English-speaking Latinos, P < .01) and discussing follow-up (62.5% of Spanish-speaking Latinos vs 79.8% English-speaking Latinos, P < .01). After adjusting for parent age, education, income, and study site, Spanish-speaking Latinos were still less likely to report high satisfaction with these communication items. Satisfaction was not different among Spanish-speaking parents when the physician spoke Spanish versus used an interpreter. Satisfaction with physician communication was associated with language but not ethnicity. Spanish-speaking parents less frequently report satisfaction with communication, and innovative solutions to enhance communication quality are needed
An Analysis of Spanish L2 Learners' Orientation through Activity Theory
ERIC Educational Resources Information Center
Tocaimaza-Hatch, C. Cecilia
2015-01-01
Orientation is defined as the way in which individuals view a task and the means they devise to fulfill it (Appel & Lantolf, 1994; Roebuck, 2000). This study investigated the orientation of twelve learners enrolled in a fourth-semester Spanish L2 university course through the analysis of their interactions during a collaborative…
Teaching English-Spanish Cognates Using the Texas 2x2 Picture Book Reading Lists
ERIC Educational Resources Information Center
Montelongo, José A.; Hernández, Anita C.; Herter, Roberta J.
2015-01-01
English-Spanish cognates are words that possess identical or nearly identical spellings and meanings in both English and Spanish as a result of being derived mainly from Latin and Greek. Of major importance is the fact that many of the more than 20,000 cognates in English are academic vocabulary words, terms essential for comprehending school…
Spanish-Language Health Communication Teaching Aids. A List of Printed Materials and Their Sources.
ERIC Educational Resources Information Center
Isquith, Robert N., Comp.; Webb, Charles T., Comp.
Over 450 Spanish printed materials about the various aspects of health and their sources are listed in this publication. Italics are used to indicate either the translation of Spanish titles or the titles of English-language editions. Publications with bilingual texts are shown by hyphenated titles. Information about the distribution of materials…
Paginas del Estudiante de Espanol (Pages for the Spanish Student)
ERIC Educational Resources Information Center
Picazo, Alfredo Carballo
1977-01-01
A complete lesson suitable for high school Spanish classes. A passage is presented, on which comprehension and vocabulary exercises are based. The grammar section deals with the subjunctive with "si" and the gerund and is accompanied by many exercises. (Text is in Spanish.) (AMH)
Guiberson, Mark; Rodríguez, Barbara L
2010-08-01
To describe the concurrent validity and classification accuracy of 2 Spanish parent surveys of language development, the Spanish Ages and Stages Questionnaire (ASQ; Squires, Potter, & Bricker, 1999) and the Pilot Inventario-III (Pilot INV-III; Guiberson, 2008a). Forty-eight Spanish-speaking parents of preschool-age children participated. Twenty-two children had expressive language delays, and 26 had typical language development. The parents completed the Spanish ASQ and the Pilot INV-III at home, and the Preschool Language Scale, Fourth Edition: Spanish Edition (PLS-4 Spanish; Zimmerman, Steiner, & Pond, 2002) was administered to the children at preschool centers. The Spanish ASQ and Pilot INV-III were significantly correlated with the PLS-4 Spanish, establishing concurrent validity. On both surveys, children with expressive language delays scored significantly lower than children with typical development. The Spanish ASQ demonstrated unacceptably low sensitivity (59%) and good specificity (92%), while the Pilot INV-III demonstrated fair sensitivity (82%) and specificity (81%). Likelihood ratios and posttest probability revealed that the Pilot INV-III may assist in detection of expressive language delays, but viewed alone it is insufficient to make an unconditional screening determination. Results suggest that Spanish parent surveys hold promise for screening language delay in Spanish-speaking preschool children; however, further refinement of these tools is needed.
Libros y mas libros: Recommended Children's Books in Spanish.
ERIC Educational Resources Information Center
Schon, Isabel
2000-01-01
Provides an annotated bibliography of recommended Spanish-language children's books. A total of 15 books are grouped in the following categories: (1) books for the very young; (2) fiction; (3) folklore; (4) literature; (5) poetry; and (6) history. (EV)
Accuracy of weight loss information in Spanish search engine results on the internet.
Cardel, Michelle I; Chavez, Sarah; Bian, Jiang; Peñaranda, Eribeth; Miller, Darci R; Huo, Tianyao; Modave, François
2016-11-01
To systematically assess the quality of online information related to weight loss that Spanish speakers in the U.S. are likely to access. This study evaluated the accessibility and quality of information for websites that were identified from weight loss queries in Spanish and compared this with previously published results in English. The content was scored with respect to five dimensions: nutrition, physical activity, behavior, pharmacotherapy, and surgical recommendations. Sixty-six websites met eligibility criteria (21 commercial, 24 news/media, 10 blogs, 0 medical/government/university, 11 unclassified sites). Of 16 possible points, mean content quality score was 3.4 (SD = 2.0). Approximately 1.5% of sites scored greater than 8 (out of 12) on nutrition, physical activity, and behavior. Unsubstantiated claims were made on 94% of the websites. Content quality scores varied significantly by type of website (P < 0.0001) with unclassified websites scoring the highest (mean = 6.3, SD = 1.4) and blogs scoring the lowest (mean = 2.2, SD = 1.2). All content quality scores were lower for Spanish websites relative to English websites. Weight loss information accessed in Spanish Web searches is suboptimal and relatively worse than weight loss information accessed in English, suggesting that U.S. Spanish speakers accessing weight loss information online may be provided with incomplete and inaccurate information. © 2016 The Obesity Society.
Burd, Nicholas A; Groen, Bart B L; Beelen, Milou; Senden, Joan M G; Gijsen, Annemie P; van Loon, Luc J C
2012-07-01
It has recently been proposed that basal muscle protein synthesis can be effectively assessed by measuring the background enrichment in total plasma protein, thereby omitting the initial biopsy, and determining the difference in enrichment from a single muscle biopsy obtained during a primed continuous infusion of isotope-labeled amino acids. We determined the reliability of calculating basal mixed muscle protein fractional synthetic rates (FSRs) from mixed plasma proteins and a single muscle biopsy compared against the sequential muscle biopsy approach. Ten men (age, 23 ± 1 years; body mass index, 22 ± 1 kg∙m(-2)) received muscle biopsies of the vastus lateralis after 2 and 4 hours of a primed continuous infusion of l-[ring-(13)C(6)]phenylalanine. Mixed muscle protein FSR was calculated from baseline plasma enrichments and muscle protein enrichments determined from the biopsy at 2 hours (1BX SHORT) or 4 hours (1BX LONG), or between muscle protein enrichments at 2 and 4 hours (2BX) of the infusion. No differences (P = .50) were observed in mixed muscle protein FSR, using plasma [ring-(13)C(6)]phenylalanine enrichments as the precursor, between the 1BX SHORT (0.031% ± 0.010%∙h(-1)), 1BX LONG (0.032% ± 0.007%∙h(-1)), or 2BX (0.035% ± 0.011%∙h(-1)) approach. A significant correlation was observed between the calculated muscle protein FSR assessed using the 1BX LONG and 2BX approach (r = 0.7, P = .02). Our data demonstrate that the single-biopsy approach, irrespective of whether the biopsy is obtained at 2 or 4 hours, can be used as a surrogate for the sequential-biopsy approach to determine basal muscle protein synthesis in a group. Copyright © 2012 Elsevier Inc. All rights reserved.
SCDC Spanish Curricula Units. Spanish SL, Unit 5, Grade 2, Supplement & Ditto Packet.
ERIC Educational Resources Information Center
Spanish Curricula Development Center, Miami Beach, FL.
The supplement and ditto packet to the Spanish SL strand of unit five for second graders provides visual materials for kits 17-20. Linguistic content of the unit was determined by its relation to the basic theme of the school as a community. Each kit treats a spiraling question. Illustrations are designed to implement oral language and conceptual…
Takaku, Michiko; Ichikawa, Seiichi; Kaneko, Noriyo
2015-01-01
This study aimed to explore the factors associated with information-seeking behaviors regarding medical institutions with Spanish language support among South American Spanish-speaking migrants living in Aichi Prefecture, Japan. The survey targeted South American Spanish-speaking migrants aged 18 years and older currently residing in Aichi Prefecture who had lived in Japan for at least three months and who had previously seen a doctor in Japan. The questionnaire was written in Spanish and the survey was conducted from April to July, 2010. Wilson's information behavior model was used to study information-seeking behavior regarding medical institutions with Spanish language support among 245 respondents who completed the questionnaires (response rate: 58.9%). Experience seeking medical institutions with Spanish language support in the Tokai area was set as the dependent variable and a chi-square test was conducted to examine relationships with language support needs, recognition of and access to medical institutions with Spanish language support, living situation in Japan, and Japanese language skills. Among the 245 respondents, 106 were male (43.3%) and 139 were female (56.7%). The average age was 39.6±11.2 years old and 84.5% were Peruvian. The average length of residency in Japan was 11.0±5.7 years, and 34.3% of respondents had lived in Aichi for 5-9 years. A total of 165 respondents (67.3%) had searched for medical institutions with Spanish language support, while 80 (32.7%) had not. Information-seeking behavior regarding medical institutions with Spanish language support was associated with having previously experienced a need for Spanish language support when seeing doctors in Japan, finding and attending medical institutions with Spanish language support in the Tokai area, length of residency in Japan, Japanese language skills, and the language used in daily life. Experience in requiring Spanish support when sick or injured in Japan motivated respondents to
Echeverri, Margarita; Anderson, David; Nápoles, Anna María
2016-01-01
Objective Describe adaptation and initial validation of the Cancer Health Literacy Test (CHLT) for Spanish-speakers. Methods Cross-sectional field test of the CHLT Spanish version (CHLT-30-DKspa) among healthy Latinos in Louisiana. Diagonally Weighted Least Squares were used to confirm the factor structure. Item-Response Analysis using 2-parameter logistic estimates were used to identify questions that may require modification to avoid bias. Cronbach's alpha coefficients estimated scale internal consistency reliability. Analysis of variance was used to test for significant differences in CHLT-30-DKspa scores by gender, origin, age and education. Results Mean CHLT-30-DKspa score (N=400) was 17.13 (range 0 to 30; SD 6.65). Results confirmed a unidimensional structure (X2[405] =461.55, p=.027, CFI=.993; TLI=.992, RMSEA=.0180). Cronbach's alpha was 0.88. Items Q1-High calorie and Q15-Tumor spread had the lowest item-scale correlations (.148 and .288) and standardized factor loadings (.152 and .302). Items Q1-High Calories, Q8-Palliative Care, and Q19-Smoking Risk had the highest item-difficulty parameters (diff=1.12, 1.21, and 2.40). Conclusions Results generally supported the applicability of the CHLT-30-DKspa for Spanish-speaking healthy populations, with the exception of four items that need to be deleted or revised and further studied Q1, Q8, Q15, and Q19). Practical Implications The CHLT-30-DKspa can be used to assess cancer health literacy among Spanish-speaking populations to advance research on cancer health literacy and outcomes. PMID:27043760
7 CFR 51.2731 - U.S. Spanish Splits.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Spanish Splits. 51.2731 Section 51.2731... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2731 U.S. Spanish Splits. “U.S. Spanish Splits” consists of shelled Spanish type peanut kernels which are split or broken...
Cervera-Acedo, C; Coloma, A; Huarte-Loza, E; Sierra-Carpio, M; Domínguez-Garrido, E
2017-10-31
Alport syndrome is an inherited renal disorder characterized by glomerular basement membrane lesions with hematuria, proteinuria and frequent hearing defects and ocular abnormalities. The disease is associated with mutations in genes encoding α3, α4, or α5 chains of type IV collagen, namely COL4A3 and COL4A4 in chromosome 2 and COL4A5 in chromosome X. In contrast to the well-known X-linked and autosomal recessive phenotypes, there is very little information about the autosomal dominant. In view of the wide spectrum of phenotypes, an exact diagnosis is sometimes difficult to achieve. We investigated a Spanish family with variable phenotype of autosomal dominant Alport syndrome using clinical, histological, and genetic analysis. Mutational analysis of COL4A3 and COL4A4 genes showed a novel heterozygous mutation (c. 998G > A; p.G333E) in exon 18 of the COL4A3 gene. Among relatives carrying the novel mutation, the clinical phenotype was variable. Two additional COL4A3 mutations were found, a Pro-Leu substitution in exon 48 (p.P1461L) and a Ser-Cys substitution in exon 49 (p.S1492C), non-pathogenics alone. Carriers of p.G333E and p.P1461L or p.S1492C mutations in COL4A3 gene appear to be more severely affected than carriers of only p.G333E mutation, and the clinical findings has an earlier onset. In this way, we could speculate on a synergistic effect of compound heterozygosity that could explain the different phenotype observed in this family.
Beltrán-Navarro, Beatriz; Abreu-Mendoza, Roberto A; Matute, Esmeralda; Rosselli, Monica
2018-01-01
This article presents a tool for assessing the early numerical abilities of Spanish-speaking Mexican preschoolers. The Numerical Abilities Test, from the Evaluación Neuropsicológica Infantil-Preescolar (ENI-P), evaluates four core abilities of number development: magnitude comparison, counting, subitizing, and basic calculation. We evaluated 307 Spanish-speaking Mexican children aged 2 years 6 months to 4 years 11 months. Appropriate internal consistency and test-retest reliability were demonstrated. We also investigated the effect of age, children's school attendance, maternal education, and sex on children's numerical scores. The results showed that the four subtests captured development across ages. Critically, maternal education had an impact on children's performance in three out of the four subtests, but there was no effect associated with children's school attendance or sex. These results suggest that the Numerical Abilities Test is a reliable instrument for Spanish-speaking preschoolers. We discuss the implications of our outcomes for numerical development.
48 CFR 252.222-7004 - Compliance with Spanish social security laws and regulations.
Code of Federal Regulations, 2012 CFR
2012-10-01
... social security laws and regulations. 252.222-7004 Section 252.222-7004 Federal Acquisition Regulations... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.222-7004 Compliance with Spanish social... Spanish Social Security Laws and Regulations (JUN 1997) (a) The Contractor shall comply with all Spanish...
48 CFR 252.222-7004 - Compliance with Spanish social security laws and regulations.
Code of Federal Regulations, 2013 CFR
2013-10-01
... social security laws and regulations. 252.222-7004 Section 252.222-7004 Federal Acquisition Regulations... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.222-7004 Compliance with Spanish social... Spanish Social Security Laws and Regulations (JUN 1997) (a) The Contractor shall comply with all Spanish...
48 CFR 252.222-7004 - Compliance with Spanish social security laws and regulations.
Code of Federal Regulations, 2014 CFR
2014-10-01
... social security laws and regulations. 252.222-7004 Section 252.222-7004 Federal Acquisition Regulations... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.222-7004 Compliance with Spanish social... Spanish Social Security Laws and Regulations (JUN 1997) (a) The Contractor shall comply with all Spanish...
48 CFR 252.222-7004 - Compliance with Spanish social security laws and regulations.
Code of Federal Regulations, 2010 CFR
2010-10-01
... social security laws and regulations. 252.222-7004 Section 252.222-7004 Federal Acquisition Regulations... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.222-7004 Compliance with Spanish social... Spanish Social Security Laws and Regulations (JUN 1997) (a) The Contractor shall comply with all Spanish...
48 CFR 252.222-7004 - Compliance with Spanish social security laws and regulations.
Code of Federal Regulations, 2011 CFR
2011-10-01
... social security laws and regulations. 252.222-7004 Section 252.222-7004 Federal Acquisition Regulations... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.222-7004 Compliance with Spanish social... Spanish Social Security Laws and Regulations (JUN 1997) (a) The Contractor shall comply with all Spanish...
Recruiting pregnant smokers from Text4baby for a randomized controlled trial of Quit4baby.
Leavitt, Leah; Abroms, Lorien; Johnson, Pamela; Schindler-Ruwisch, Jennifer; Bushar, Jessica; Singh, Indira; Cleary, Sean D; McInvale, Whitney; Turner, Monique
2017-06-01
Recruiting pregnant smokers into clinical trials is challenging since this population tends to be disadvantaged, the behavior is stigmatized, and the intervention window is limited. The purpose of this study is to test the feasibility and effectiveness of recruiting pregnant smokers into a smoking cessation trial by sending recruitment text messages to an existing subscriber list. Recruitment messages were sent to subscribers flagged as pregnant in Text4baby, a national text messaging program for pregnant women and mothers. Four recruitment messages were rotated to test the effectiveness of different emotional frames and a financial incentive. Study staff called subscribers who expressed interest to screen for eligibility and enroll eligible women. Between October 6, 2015 and February 2, 2016, 10,194 recruitment messages were sent to Text4baby subscribers flagged as pregnant, and 10.18% (1038) responded indicating interest. No significant increase in cancellation was observed compared to subscribers who received other ad hoc messages. Of respondents, 54.05% (561) were reached by phone for follow-up, and 21.97% (228) were found to be eligible. Among the eligible, 87% (199) pregnant smokers enrolled. The recruitment message with a pride emotional appeal had a significantly higher response (p = 0.02) compared to the recruitment message with no emotional appeal, but enrollment did not significantly differ between recruitment messages with different emotional appeals. The recruitment messages with a reference to financial incentive yielded higher response (p < 0.01) and enrollment (p = 0.03) compared to a recruitment message without. This study demonstrates success recruiting pregnant smokers using text message. Future studies should consider building on this approach for recruiting high-risk populations.
ERIC Educational Resources Information Center
Lleo, Conxita
2006-01-01
This article examines the constraints on Prosodic Word production in Spanish by three monolingual and three Spanish-German bilingual children from the beginning of word production until 2;2. It also considers the relationship between Prosodic Words and Phonological Phrases, and in the case of monosyllabic words, it takes into consideration…
ERIC Educational Resources Information Center
Raynolds, Laura B.; López-Velásquez, Angela; Olivo Valentín, Laura E.
2017-01-01
Twenty-five 4- and 5-year-old Spanish-speaking English Learners (ELs) were tested in order to compare their English and Spanish performance in two phonological awareness skills: Rhyme awareness (RA) and beginning sound segmentation (BSS). The children had received formal instruction of phonological awareness, with an emphasis on RA and BSS for…
Cost-Effectiveness Analysis of the Spanish Renal Replacement Therapy Program
Villa, Guillermo; Fernández–Ortiz, Lucía; Cuervo, Jesús; Rebollo, Pablo; Selgas, Rafael; González, Teresa; Arrieta, Javier
2012-01-01
♦ Background: We undertook a cost-effectiveness analysis of the Spanish Renal Replacement Therapy (RRT) program for end-stage renal disease patients from a societal perspective. The current Spanish situation was compared with several hypothetical scenarios. ♦ Methods: A Markov chain model was used as a foundation for simulations of the Spanish RRT program in three temporal horizons (5, 10, and 15 years). The current situation (scenario 1) was compared with three different scenarios: increased proportion of overall scheduled (planned) incident patients (scenario 2); constant proportion of overall scheduled incident patients, but increased proportion of scheduled incident patients on peritoneal dialysis (PD), resulting in a lower proportion of scheduled incident patients on hemodialysis (HD) (scenario 3); and increased overall proportion of scheduled incident patients together with increased scheduled incidence of patients on PD (scenario 4). ♦ Results: The incremental cost-effectiveness ratios (ICERs) of scenarios 2, 3, and 4, when compared with scenario 1, were estimated to be, respectively, –€83 150, –€354 977, and –€235 886 per incremental quality-adjusted life year (ΔQALY), evidencing both moderate cost savings and slight effectiveness gains. The net health benefits that would accrue to society were estimated to be, respectively, 0.0045, 0.0211, and 0.0219 ΔQALYs considering a willingness-to-pay threshold of €35 000/ΔQALY. ♦ Conclusions: Scenario 1, the current Spanish situation, was dominated by all the proposed scenarios. Interestingly, scenarios 3 and 4 showed the best results in terms of cost-effectiveness. From a cost-effectiveness perspective, an increase in the overall scheduled incidence of RRT, and particularly that of PD, should be promoted. PMID:21965620
ERIC Educational Resources Information Center
Stering, Edward
This document shares a vision for a 4-year curriculum for Heritage Speakers of Spanish (HSS)/Spanish for Native Speakers (SNS), describing a course developed for SNS students within Mercy High School in San Francisco, California. The vision foresees an ever-increasing number of HSS and SNS students completing college level degree programs then…
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ERIC Educational Resources Information Center
Martínez-Roldan, Carmen M.
2013-01-01
This study illustrates the presence of Mock Spanish in some English-based picture books and the ways this usage misrepresents Latino people, language, and culture. The author conducted a critical content analysis of five Skippyjon Jones books. Her guiding question was, How is language used, particularly Spanish, in these English texts, and what…
OSCAR4: a flexible architecture for chemical text-mining.
Jessop, David M; Adams, Sam E; Willighagen, Egon L; Hawizy, Lezan; Murray-Rust, Peter
2011-10-14
The Open-Source Chemistry Analysis Routines (OSCAR) software, a toolkit for the recognition of named entities and data in chemistry publications, has been developed since 2002. Recent work has resulted in the separation of the core OSCAR functionality and its release as the OSCAR4 library. This library features a modular API (based on reduction of surface coupling) that permits client programmers to easily incorporate it into external applications. OSCAR4 offers a domain-independent architecture upon which chemistry specific text-mining tools can be built, and its development and usage are discussed.
OSCAR4: a flexible architecture for chemical text-mining
2011-01-01
The Open-Source Chemistry Analysis Routines (OSCAR) software, a toolkit for the recognition of named entities and data in chemistry publications, has been developed since 2002. Recent work has resulted in the separation of the core OSCAR functionality and its release as the OSCAR4 library. This library features a modular API (based on reduction of surface coupling) that permits client programmers to easily incorporate it into external applications. OSCAR4 offers a domain-independent architecture upon which chemistry specific text-mining tools can be built, and its development and usage are discussed. PMID:21999457
[The advertising message of drugs advertisements in Spanish medical journals].
Riera, Eusebi J Castaño; de la Fuente, David Oterino; Rodrígueza, Rosa M Rodríguez
2007-01-01
To describe the characteristics of advertising in Spanish medical journals and to analyze the advertising message in drug advertisements. Six issues of 4 Spanish medical journals published in 2001 were reviewed to identify the number of advertisements and their characteristics. The journals selected were Atención Primaria, Anales Españoles de Pediatría, Medicina Clínica and Gaceta Sanitaria. The advertising message was analyzed by evaluating 5 factors: communication aim, sales argument, communication treatment, and use of text and image. 609 advertisements were found. Drug advertisements were the most numerous (69.9%). Advertising pressure was highest in Atención Primaria (36%), followed by Anales Españoles de Pediatría (22%), Medicina Clínica (12%) and Gaceta Sanitaria (4%). Of the 195 drug advertisements analyzed, the aim of the advertising message was mostly to present or remind readers of an existing product (70.8%). The sales argument was rational in 86.5%. The communication treatment was advertising in 72.6%. The text of the advertisement contained a headline in 82.4% or a slogan in 50.8%. The advertisement image was a photograph in 74.7% and the aim of the image was to present the product (48.7%), to promise a benefit (45.1%), or to argue its qualities (31.1%). In the journals aimed at prescribing physicians advertising pressure was higher and advertisements were intercalated in article text. Advertising concerned already existing products, used rational arguments, and the communication treatment was advertising.
Satisfaction With Communication In Primary Care For Spanish-Speaking And English-Speaking Parents
Flower, Kori B.; Skinner, Asheley C.; Yin, H. Shonna; Rothman, Russell L.; Sanders, Lee M.; Delamater, Alan; Perrin, Eliana M.
2017-01-01
Background and Objective Effective communication with primary care physicians is important yet incompletely understood for Spanish-speaking parents. We predicted lower satisfaction among Spanish-speaking compared with English-speaking Latino and non-Latino parents. Methods Cross-sectional analysis at 2-month well visits within the Greenlight study at 4 pediatric resident clinics. Parents reported satisfaction with 14 physician communication items using the validated Communication Assessment Tool (CAT). High satisfaction was defined as “excellent” on each CAT item. Mean estimations compared satisfaction for communication items among Spanish and English-speaking Latinos and non-Latinos. We used generalized linear regression modeling, adjusted for parent age, education, income, and clinic site. Among Spanish-speaking parents, we compared visits conducted in Spanish with and without an interpreter, and in English. Results Compared with English-speaking Latino (N=127) and non-Latino parents (N=432), fewer Spanish-speaking parents (N=303) reported satisfaction with 14 communication items. No significant differences were found between English-speaking Latinos and non-Latinos. Greatest differences were found in: greeting that made the parent comfortable (59.4% of Spanish-speaking Latinos endorsing “Excellent” vs. 77.5% English-speaking Latinos, p<0.01) and discussing follow-up (62.5% of Spanish-speaking Latinos vs. 79.8% English-speaking Latinos, p<0.01). After adjusting for parent age, education, income, and study site, Spanish-speaking Latinos were still less likely to report high satisfaction with these communication items. Satisfaction was not different among Spanish-speaking parents when the physician spoke Spanish versus used an interpreter. Conclusions Satisfaction with physician communication was associated with language, but not ethnicity. Spanish-speaking parents less frequently report satisfaction with communication, and innovative solutions to enhance
Yin, H Shonna; Sanders, Lee M; Rothman, Russell L; Mendelsohn, Alan L; Dreyer, Benard P; White, Richard O; Finkle, Joanne P; Prendes, Stefania; Perrin, Eliana M
2012-01-01
To assess the health literacy and numeracy skills of Spanish-speaking parents of young children and to validate a new Spanish language health literacy assessment for parents, the Spanish Parental Health Literacy Activities Test (PHLAT Spanish). Cross-sectional study of Spanish-speaking caregivers of young children (<30 months) enrolled at primary care clinics in 4 academic medical centers. Caregivers were administered the 10-item PHLAT in addition to validated tests of health literacy (S-TOFHLA) and numeracy (WRAT-3 Arithmetic). Psychometric analysis was used to examine item characteristics of the PHLAT-10 Spanish, to assess its correlation with sociodemographics and performance on literacy/numeracy assessments, and to generate a shorter 8-item scale (PHLAT-8). Of 176 caregivers, 77% had adequate health literacy (S-TOFHLA), whereas only 0.6% had 9th grade or greater numeracy skills. Mean PHLAT-10 score was 41.6% (SD 21.1). Fewer than one-half (45.5%) were able to read a liquid antibiotic prescription label and demonstrate how much medication to administer within an oral syringe. Less than one-third (31.8%) were able to interpret a food label to determine whether it met WIC (Special supplemental nutrition program for Women, Infants, and Children) guidelines. Greater PHLAT-10 score was associated with greater years of education (r = 0.49), S-TOFHLA (r = 0.53), and WRAT-3 (r = 0.55) scores (P < .001). Internal reliability was good (Kuder-Richardson coefficient of reliability; KR-20 = 0.61). An 8-item scale was highly correlated with the full 10-item scale (r = 0.97, P < .001), with comparable internal reliability (KR-20 = 0.64). Many Spanish-speaking parents have difficulty performing health-related literacy and numeracy tasks. The Spanish PHLAT demonstrates good psychometric characteristics and may be useful for identifying parents who would benefit from receiving low-literacy child health information. Copyright © 2012 Academic Pediatric Association. Published
Mi Lengua: Spanish as a Heritage Language in the United States.
ERIC Educational Resources Information Center
Roca, Ana, Ed.; Colombi, M. Cecilia, Ed.
This collection of papers includes the following: (1) "Insights from Research and Practice in Spanish as a Heritage Language" (M. Cecilia Colombi and Ana Roca); (2) "Toward a Theory of Heritage Language Acquisition: Spanish in the United States" (Andrew Lynch); (3) "Profiles of SNS Students in the Twenty-First Century:…
ERIC Educational Resources Information Center
Ramos, Jose A.
2012-01-01
Through a single-subject multiple-baseline across-participants design, the present study examined the effects of Reciprocal Teaching (RT) instruction and Spanish use on the cognitive strategy use and English reading comprehension of four, 4th grade Spanish-speaking bilingual students that are "good" decoders but "poor"…
A Spanish matrix sentence test for assessing speech reception thresholds in noise.
Hochmuth, Sabine; Brand, Thomas; Zokoll, Melanie A; Castro, Franz Zenker; Wardenga, Nina; Kollmeier, Birger
2012-07-01
To develop, optimize, and evaluate a new Spanish sentence test in noise. The test comprises a basic matrix of ten names, verbs, numerals, nouns, and adjectives. From this matrix, test lists of ten sentences with an equal syntactical structure can be formed at random, with each list containing the whole speech material. The speech material represents the phoneme distribution of the Spanish language. The test was optimized for measuring speech reception thresholds (SRTs) in noise by adjusting the presentation levels of the individual words. Subsequently, the test was evaluated by independent measurements investigating the training effects, the comparability of test lists, open-set vs. closed-set test format, and performance of listeners of different Spanish varieties. In total, 68 normal-hearing native Spanish-speaking listeners. SRTs measured using an adaptive procedure were 6.2 ± 0.8 dB SNR for the open-set and 7.2 ± 0.7 dB SNR for the closed-set test format. The residual training effect was less than 1 dB after using two double-lists before data collection. No significant differences were found for listeners of different Spanish varieties indicating that the test is applicable to Spanish as well as Latin American listeners. Test lists can be used interchangeably.
ERIC Educational Resources Information Center
Rothman, Jason; Long, Drew; Iverson, Michael; Judy, Tiffany; Lingwall, Anne; Chakravarty, Tushar
2016-01-01
We report a longitudinal comprehension study of (long) passive constructions in two native-Spanish child groups differing by age of initial exposure to L2 English (young group: 3;0-4;0; older group: 6;0-7;0), where amount of input, L2 exposure environment, and socioeconomic status are controlled. Data from a forced-choice task show that both…
Čeponytė, Ugnė; Paškevičiūtė, Miglė; Petrikaitė, Vilma
2018-01-01
Purpose In this study, we evaluated the anticancer activity of non-steroidal anti-inflammatory drugs (NSAIDs) in BxPC-3 and MIA PaCa-2 pancreatic cancer cell cultures. Methods To test the effect of compounds on the viability of cells, the MTT assay was used. The activity of NSAIDs in 3D cell cultures was evaluated by measuring the size change of spheroids. The type of cell death was identified by cell staining with Hoechst 33342 and propidium iodide. To evaluate the effect on the colony-forming ability of cancer cells, the clonogenic assay was used. Results Five out of seven tested NSAIDs reduced the viability of BxPC-3 and MIA PaCa-2 cancer cells. Fenamates were more active against cyclooxygenase-2 expressing BxPC-3 than cyclooxygenase-2 non-expressing MIA PaCa-2 cell line. Fenamates and coxibs exerted higher activity in monolayer cultured cells, whereas salicylates were more active in 3D cultures. Fenamates and coxibs induced dose-dependent apoptosis and necrosis. NSAIDs also inhibited the colony-forming ability of cancer cells. Meclofenamic acid, niflumic acid, and parecoxib possessed higher activity on BxPC-3, and celecoxib possessed higher activity on MIA PaCa-2 cell colony formation. Conclusion Our results show that fenamates, coxibs, and salicylates possess anticancer activity on human pancreatic cancer BxPC-3 and MIA PaCa-2 cell cultures. PMID:29942156
Mutational screening of the USH2A gene in Spanish USH patients reveals 23 novel pathogenic mutations
2011-01-01
Background Usher Syndrome type II (USH2) is an autosomal recessive disorder, characterized by moderate to severe hearing impairment and retinitis pigmentosa (RP). Among the three genes implicated, mutations in the USH2A gene account for 74-90% of the USH2 cases. Methods To identify the genetic cause of the disease and determine the frequency of USH2A mutations in a cohort of 88 unrelated USH Spanish patients, we carried out a mutation screening of the 72 coding exons of this gene by direct sequencing. Moreover, we performed functional minigene studies for those changes that were predicted to affect splicing. Results As a result, a total of 144 DNA sequence variants were identified. Based upon previous studies, allele frequencies, segregation analysis, bioinformatics' predictions and in vitro experiments, 37 variants (23 of them novel) were classified as pathogenic mutations. Conclusions This report provide a wide spectrum of USH2A mutations and clinical features, including atypical Usher syndrome phenotypes resembling Usher syndrome type I. Considering only the patients clearly diagnosed with Usher syndrome type II, and results obtained in this and previous studies, we can state that mutations in USH2A are responsible for 76.1% of USH2 disease in patients of Spanish origin. PMID:22004887
ERIC Educational Resources Information Center
Cena, Johanna; Baker, Doris Luft; Kame'enui, Edward J.; Baker, Scott K.; Park, Yonghan; Smolkowski, Keith
2013-01-01
This study examined the impact of a 15-min daily explicit vocabulary intervention in Spanish on expressive and receptive vocabulary knowledge and oral reading fluency in Spanish, and on language proficiency in English. Fifty Spanish-speaking English learners who received 90 min of Spanish reading instruction in an early transition model were…
[Spanish international cooperation in health].
Mazarrasa-Alvear, Lucía; Montero-Corominas, María José
2004-05-01
In this chapter, there is a view of the relationships between the Spanish policy for international cooperation aid and the main health problems of the developing world, with a gender perspective. The population health is a result of the development inequity between rich and poor countries. The international institutions have established the frame and priorities of the cooperation aid, being poverty eradication the main priority. The compromise of the Millennium Conference was to reduce in 2/3 child mortality and 3/4 maternal mortality before year 2015, to stop and reduce HIV-AIDS, malaria and others serious diseases as tuberculosis and to facilitate developing countries the access to drugs. Although the resources allocated, the total amount for cooperation has been reduced 30% during the last years. The Spanish AOD in health is difficult to account because it is considered among social basic services and it is not addressed to solve the main health problems in the poorest countries.
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2010-08-19
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Age of acquisition and allophony in Spanish-English bilinguals
Barlow, Jessica A.
2014-01-01
This study examines age of acquisition (AoA) in Spanish-English bilinguals’ phonetic and phonological knowledge of /l/ in English and Spanish. In English, the lateral approximant /l/ varies in darkness by context [based on the second formant (F2) and the difference between F2 and the first formant (F1)], but the Spanish /l/ does not. Further, English /l/ is overall darker than Spanish /l/. Thirty-eight college-aged adults participated: 11 Early Spanish-English bilinguals who learned English before the age of 5 years, 14 Late Spanish-English bilinguals who learned English after the age of 6 years, and 13 English monolinguals. Participants’ /l/ productions were acoustically analyzed by language and context. The results revealed a Spanish-to-English phonetic influence on /l/ productions for both Early and Late bilinguals, as well as an English-to-Spanish phonological influence on the patterning of /l/ for the Late Bilinguals. These findings are discussed in terms of the Speech Learning Model and the effect of AoA on the interaction between a bilingual speaker’s two languages. PMID:24795664
Age of acquisition and allophony in Spanish-English bilinguals.
Barlow, Jessica A
2014-01-01
This study examines age of acquisition (AoA) in Spanish-English bilinguals' phonetic and phonological knowledge of /l/ in English and Spanish. In English, the lateral approximant /l/ varies in darkness by context [based on the second formant (F2) and the difference between F2 and the first formant (F1)], but the Spanish /l/ does not. Further, English /l/ is overall darker than Spanish /l/. Thirty-eight college-aged adults participated: 11 Early Spanish-English bilinguals who learned English before the age of 5 years, 14 Late Spanish-English bilinguals who learned English after the age of 6 years, and 13 English monolinguals. Participants' /l/ productions were acoustically analyzed by language and context. The results revealed a Spanish-to-English phonetic influence on /l/ productions for both Early and Late bilinguals, as well as an English-to-Spanish phonological influence on the patterning of /l/ for the Late Bilinguals. These findings are discussed in terms of the Speech Learning Model and the effect of AoA on the interaction between a bilingual speaker's two languages.
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ERIC Educational Resources Information Center
Garcia, Eugene E.; And Others
Six hundred, 4-, 5-, and 6-year-old bilingual, rural, and urban children from southwestern, midwestern, eastern, and southern United States participated in a national study of Spanish/English bilingual development. Half of these children completed the English version of CIRCO (1980) sub-test 10-C, a productive language measure that requires…
[Validation of a Spanish version of the Childhood Asthma Control Test (Sc-ACT) for use in Spain].
Pérez-Yarza, E G; Castro-Rodriguez, J A; Villa Asensi, J R; Garde Garde, J; Hidalgo Bermejo, F J
2015-08-01
The Childhood Asthma Control Test (c-ACT) is a validated tool for determining pediatric asthma control. However, it is not validated in the Spanish language in Spain. We evaluated the psychometric properties of the Spanish version of the Childhood Asthma Control Test (Sc-ACT) for assessing asthma control in children ages 4 to11. This national, multicentre, prospective study was conducted in Spain with asthmatic children and their caregivers. Patients were assessed at 3 visits (Baseline, 2 Weeks, and 4 Months). Clinical variables included: symptoms, exacerbations, FEV1, asthma classification, PAQLQ and PACQLQ questionnaire scores, and asthma control as perceived by physicians, patients and caregivers. The Sc-ACT feasibility, validity, reliability, and sensitivity to change were assessed. A total of 394 children were included; mean (SD) time to complete the Sc-ACT was 5.3 (4.4) minutes. Sc-ACT score was correlated with asthma control as perceived by physician (-0.52), patient (-0.53), and caregiver (-0.51) and with the PAQLQ (0.56) and PACQLQ (0.55) scores. Sc-ACT was found to be significantly related to intensity and frequency of asthma symptoms. Cronbach alpha coefficient α was 0.81 and intraclass correlation coefficient was ≥0.85 for all of the items. The global effect size of Sc-ACT was 0.55. The cutoff point scores of 21 or higher indicated a good asthma control and their MCID was 4 points. The Spanish version of the c-ACT was found to be a reliable and valid questionnaire for evaluating asthma control in Spanish-speaking children ages 4 to 11 in Spain. Copyright © 2014 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.
Spanish Literacy Investigation Project.
ERIC Educational Resources Information Center
Cook, Jacqueline; Quinones, Anisia
The Spanish Literacy Investigation Project was implemented to identify adult Spanish literacy programs throughout the country, to explore the availability of relevant Spanish literacy teaching methods, to determine relevant elements between Spanish literacy and English as a Second Language (ESL), and to describe a model for incorporating a Spanish…
ERIC Educational Resources Information Center
DeFeo, Dayna Jean
2015-01-01
This article presents a case study of the perceptions of Spanish heritage speakers enrolled in introductory-level Spanish foreign language courses. Despite their own identities that were linked to the United States and Spanish of the Borderlands, the participants felt that the curriculum acknowledged the Spanish of Spain and foreign countries but…
The Gap between Spanish Speakers' Word Reading and Word Knowledge: A Longitudinal Study
ERIC Educational Resources Information Center
Mancilla-Martinez, Jeannette; Lesaux, Nonie K.
2011-01-01
This longitudinal study modeled growth rates, from ages 4.5 to 11, in English and Spanish oral language and word reading skills among 173 Spanish-speaking children from low-income households. Individual growth modeling was employed using scores from standardized measures of word reading, expressive vocabulary, and verbal short-term language…
Spanish Peaks, Sangre de Cristo Range, Colorado
NASA Technical Reports Server (NTRS)
2002-01-01
The Spanish Peaks, on the eastern flank of the Sangre de Cristo range, abruptly rise 7,000 feet above the western Great Plains. Settlers, treasure hunters, trappers, gold and silver miners have long sighted on these prominent landmarks along the Taos branch of the Santa Fe trail. Well before the westward migration, the mountains figured in the legends and history of the Ute, Apache, Comanche, and earlier tribes. 'Las Cumbres Espanolas' are also mentioned in chronicles of exploration by Spaniards including Ulibarri in 1706 and later by de Anza, who eventually founded San Francisco (California). This exceptional view (STS108-720-32), captured by the crew of Space Shuttle mission STS108, portrays the Spanish Peaks in the context of the southern Rocky Mountains. Uplift of the Sangre de Cristo began about 75 million years ago and produced the long north-trending ridges of faulted and folded rock to the west of the paired peaks. After uplift had ceased (26 to 22 million years ago), the large masses of igneous rock (granite, granodiorite, syenodiorite) that form the Peaks were emplaced (Penn, 1995-2001). East and West Spanish Peaks are 'stocks'-bodies of molten rock that intruded sedimentary layers, cooled and solidified, and were later exposed by erosion. East Peak (E), at 12,708 ft is almost circular and is about 5 1/2 miles long by 3 miles wide, while West Peak (W), at 13,623 ft is roughly 2 3/4 miles long by 1 3/4 miles wide. Great dikes-long stone walls-radiate outward from the mountains like spokes of a wheel, a prominent one forms a broad arc northeast of East Spanish Peak. As the molten rock rose, it forced its way into vertical cracks and joints in the sedimentary strata; the less resistant material was then eroded away, leaving walls of hard rock from 1 foot to 100 feet wide, up to 100 feet high, and as long as 14 miles. Dikes trending almost east-west are also common in the region. For more information visit: Sangres.com: The Spanish Peaks (accessed January 16
Identifying Spanish-English Cognates to Scaffold Instruction for Latino ELs
ERIC Educational Resources Information Center
Montelongo, Jose A.; Hernandez, Anita; Herter, Roberta Joan
2011-01-01
Spanish-English cognates have been used for decades to facilitate the acquisition of English by Latino English learners (ELs). Using the online program, WordSift, in tandem with the online Find-a-Cognate database, teachers can identify important Spanish-English cognates and noncognate words in text. With this information, teachers can plan and…
Teaching Spanish to the Spanish-Speaking Child, 1965-1968. Report.
ERIC Educational Resources Information Center
Digneo, Ellen Hartnett, Ed.; Shaya, Tila, Ed.
Realization by educators of the educational problems faced by Spanish-speaking children resulted in a 1965-68 Western States Small Schools Project at Pecos, New Mexico, which sought to establish the study of Spanish as an integral part of daily classroom activities in the elementary school. The objectives of the Spanish Program were (1) to…
SCDC Spanish Curricula Units. Spanish SL Strand, Unit 6, Grade 2, Supplement & Ditto Packet.
ERIC Educational Resources Information Center
Spanish Curricula Development Center, Miami Beach, FL.
The supplement and ditto packet to the Spanish as a Second Language strand of unit six for second graders contains activities for both seatwork and group participation. Unit six is oriented toward the basic theme of the neighborhood as a community; Kits 21-24 reflect the spiraling questions of what the elements are, how wants and needs are…
The Storage and Processing of Morphologically Complex Words in L2 Spanish
ERIC Educational Resources Information Center
Foote, Rebecca
2017-01-01
Research with native speakers indicates that, during word recognition, regularly inflected words undergo parsing that segments them into stems and affixes. In contrast, studies with learners suggest that this parsing may not take place in L2. This study's research questions are: Do L2 Spanish learners store and process regularly inflected,…
Text Message Support for Weight Loss in Patients With Prediabetes: A Randomized Clinical Trial.
Fischer, Henry H; Fischer, Ilana P; Pereira, Rocio I; Furniss, Anna L; Rozwadowski, Jeanne M; Moore, Susan L; Durfee, Michael J; Raghunath, Silvia G; Tsai, Adam G; Havranek, Edward P
2016-08-01
Although the benefits of in-person Diabetes Prevention Program (DPP) classes for diabetes prevention have been demonstrated in trials, effectiveness in clinical practice is limited by low participation rates. This study explores whether text message support enhances weight loss in patients offered DPP classes. English- and Spanish-speaking patients with prediabetes (n = 163) were randomized to the control group, which only received an invitation to DPP classes as defined by the Centers for Disease Control and Prevention, or to the text message-augmented intervention group, which also received text messages adapted from the DPP curriculum for 12 months. Mean weight decreased 0.6 pounds (95% CI -2.7 to 1.6) in the control group and 2.6 pounds (95% CI -5.5 to 0.2) in the intervention group (P value 0.05). Three percent weight loss was achieved by 21.5% of participants in the control group (95% CI 12.5-30.6), compared with 38.5% in the intervention group (95% CI 27.7-49.3) (absolute difference 17.0%; P value 0.02). Mean glycated hemoglobin (HbA1c) increased by 0.19% or 2.1 mmol/mol (95% CI -0.1 to 0.5%) and decreased by 0.09% or 1.0 mmol/mol (95% CI -0.2 to 0.0%) in the control group and intervention participants, respectively (absolute difference 0.28%; P value 0.07). Stratification by language demonstrated a significant treatment effect in Spanish speakers but not in English speakers. Text message support can lead to clinically significant weight loss in patients with prediabetes. Further study assessing effect by primary language and in an operational setting is warranted. © 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.
Howard, Elizabeth R.; Green, Jennifer D.; Arteagoitia, Igone
2014-01-01
This study contributes to the literature on cross-linguistic literacy relationships for English language learners, and in particular, the Spanish-influenced spelling patterns of Spanish-English bilinguals. English spelling, reading and vocabulary assessments were administered to 220 students in four TWI programs over a three-year period, from 2nd grade to 4th grade. Data analysis consisted of t-tests and multiple regression. The incidence of cross-linguistic spelling errors was found to be low at all grade levels and to virtually disappear by 4th grade, indicating that this is a developmental issue that is common among bilingual students and that resolves itself without remediation. PMID:25302051
Gildersleeve-Neumann, Christina E; Kester, Ellen S; Davis, Barbara L; Peña, Elizabeth D
2008-07-01
English speech acquisition by typically developing 3- to 4-year-old children with monolingual English was compared to English speech acquisition by typically developing 3- to 4-year-old children with bilingual English-Spanish backgrounds. We predicted that exposure to Spanish would not affect the English phonetic inventory but would increase error frequency and type in bilingual children. Single-word speech samples were collected from 33 children. Phonetically transcribed samples for the 3 groups (monolingual English children, English-Spanish bilingual children who were predominantly exposed to English, and English-Spanish bilingual children with relatively equal exposure to English and Spanish) were compared at 2 time points and for change over time for phonetic inventory, phoneme accuracy, and error pattern frequencies. Children demonstrated similar phonetic inventories. Some bilingual children produced Spanish phonemes in their English and produced few consonant cluster sequences. Bilingual children with relatively equal exposure to English and Spanish averaged more errors than did bilingual children who were predominantly exposed to English. Both bilingual groups showed higher error rates than English-only children overall, particularly for syllable-level error patterns. All language groups decreased in some error patterns, although the ones that decreased were not always the same across language groups. Some group differences of error patterns and accuracy were significant. Vowel error rates did not differ by language group. Exposure to English and Spanish may result in a higher English error rate in typically developing bilinguals, including the application of Spanish phonological properties to English. Slightly higher error rates are likely typical for bilingual preschool-aged children. Change over time at these time points for all 3 groups was similar, suggesting that all will reach an adult-like system in English with exposure and practice.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fujita, Mayumi; Imadome, Kaori; Shoji, Yoshimi
2015-09-01
Purpose: To investigate the mechanisms underlying the inhibition of cancer cell migration and invasion by carbon (C)-ion irradiation. Methods and Materials: Human pancreatic cancer cells MIAPaCa-2, AsPC-1, and BxPC-3 were treated by x-ray (4 Gy) or C-ion (0.5, 1, 2, or 4 Gy) irradiation, and their migration and invasion were assessed 2 days later. The levels of guanosine triphosphate (GTP)-bound Rac1 and RhoA were determined by the active GTPase pull-down assay with or without a proteasome inhibitor, and the binding of E3 ubiquitin ligase to GTP-bound Rac1 was examined by immunoprecipitation. Results: Carbon-ion irradiation reduced the levels of GTP-bound Rac1 and RhoA, 2more » major regulators of cell motility, in MIAPaCa-2 cells and GTP-bound Rac1 in AsPC-1 and BxPC-3 cells. Proteasome inhibition reversed the effect, indicating that C-ion irradiation induced Rac1 and RhoA degradation via the ubiquitin (Ub)-proteasome pathway. E3 Ub ligase X-linked inhibitor of apoptosis protein (XIAP), which directly targets Rac1, was selectively induced in C-ion–irradiated MIAPaCa-2 cells and coprecipitated with GTP-bound Rac1 in C-ion–irradiated cells, which was associated with Rac1 ubiquitination. Cell migration and invasion reduced by C-ion radiation were restored by short interfering RNA–mediated XIAP knockdown, indicating that XIAP is involved in C-ion–induced inhibition of cell motility. Conclusion: In contrast to x-ray irradiation, C-ion treatment inhibited the activity of Rac1 and RhoA in MIAPaCa-2 cells and Rac1 in AsPC-1 and BxPC-3 cells via Ub-mediated proteasomal degradation, thereby blocking the motility of these pancreatic cancer cells.« less
ERIC Educational Resources Information Center
Pellerin, Martine; Montes, Carlos Soler
2012-01-01
The study explores the effectiveness of the implementation of blended teaching (BT) by combining the Spanish online resource "Aula Virtual de Espanol" (AVE) with the face-to-face (F2F) delivery approach in second language Spanish programs in two high schools in Alberta, Canada. Findings demonstrate the effectiveness of combining the…
A Formative Study: Inquiry and Informational Text with Fifth-Grade Bilinguals
ERIC Educational Resources Information Center
Moses, Lindsey
2014-01-01
This article includes the findings from a formative experiment implementing inquiry with informational texts in a fifth-grade bilingual classroom after the completion of state assessments. The pedagogical goals were focused on facilitating engaged reading and writing for native Spanish-speakers and building content knowledge and related academic…
Abroms, Lorien C; Ahuja, Meenakshi; Kodl, Yvonne; Thaweethai, Lalida; Sims, Justin; Winickoff, Jonathan P; Windsor, Richard A
2012-01-01
Text messaging programs on mobile phones have shown some promise in helping people quit smoking. Text2Quit is an automated, personalized, and interactive mobile health program that sends text messages and e-mails timed around a participant's quit date over the course of 3 months. The text messages include pre- and post-quit educational messages, peer ex-smoker messages, medication reminders and relapse messages, and multiple opportunities for interaction. Study participants were university students (N = 23) enrolled in the Text2Quit program. Participants were surveyed at baseline and at 2 and 4 weeks after enrollment. The majority of participants agreed that they liked the program at 2 and 4 weeks after enrollment (90.5% and 82.3%, respectively). Support for text messages was found to be moderate and higher than that of the e-mail and web components. Of participants, 75% reported reading most or all of the texts. On average, users made 11.8 responses to the texts over a 4-week period, although responses declined after the quit date. The interactive feature for tracking cigarettes was the most used interactive feature, followed by the craving trivia game. This pilot test provides some support for the Text2Quit program. A future iteration of the program will include additional tracking features in both the pre-quit and post-quit protocols and an easier entry into the not-quit protocol. Future studies are recommended that identify the value of the interactive and personalized features that characterize this program.
ABROMS, LORIEN C.; AHUJA, MEENAKSHI; KODL, YVONNE; THAWEETHAI, LALIDA; SIMS, JUSTIN; WINICKOFF, JONATHAN; WINDSOR, RICHARD A.
2012-01-01
Text messaging programs on mobile phones have shown some promise in helping people quit smoking. Text2Quit is an automated, personalized and interactive mobile health program that sends text messages and emails timed around a participant’s quit date over the course of 3 months. The text messages include pre- and post-quit educational messages, peer ex-smoker messages, medication reminders and relapse messages, as well as multiple opportunities for interaction. Study participants were university students (n=23) enrolled in the Text2Quit program. Participants were surveyed at baseline and at 2 and 4 weeks post-enrollment. The vast majority of participants agreed that they liked the program at 2 and 4 weeks post-enrollment (90.5% and 82.3%, respectively). Support for text messages was found to be moderate, and higher than that of the email and web components. Seventy-five percent of participants reported reading most or all of the texts. On average, users made 11.8 responses to the texts over a 4 week period, although responses declined following the quit date. The interactive feature for tracking cigarettes was the most used interactive feature, followed by the craving trivia game. This pilot test provides some support for the Text2Quit program. A future iteration of the program will include additional tracking features in both the pre-quit and post-quit protocol and an easier entry into the not-quit protocol. Future studies are recommended that identify the value of the interactive and personalized features that characterize this program. PMID:22548598
Cremades Pallas, R; Burbano, P; Valcárcel de la Iglesia, M A; Burillo-Putze, G; Martín-Sánchez, F J; Miró, Ò
2013-01-01
To analyze the impact of articles published in English compared to those published in Spanish in multilingual Spanish biomedical journals. We analyzed the language of publication, the number of original articles, the nationality of the authors, the citations received, the citing article and the nationality of the citing authors among the articles published from 2008-2012 in 5 multilingual Spanish biomedical journals. The study included 4,296 documents, 85 of which were published in English (2%). The percentage of original articles and of non-Spanish authorship was significantly higher among these latter articles and they also achieved more citations and more citing articles per article published. The proportion of articles published in English by multilingual Spanish biomedical journals is low and they are more often originals signed exclusively by foreign authors and receive more citations than those published in Spanish, which are also more frequently made by foreign authors.
Language Growth in English Monolingual and Spanish-English Bilingual Children from 2.5 to 5 Years.
Hoff, Erika; Ribot, Krystal M
2017-11-01
To describe the trajectories of English and Spanish language growth in typically developing children from bilingual homes and compare those with the trajectories of English growth in children from monolingual homes, to assess effects of dual language exposure on language growth in typically developing children. Expressive vocabularies were assessed at 6-month intervals from age 30 to 60 months, in English for monolinguals and English and Spanish for bilinguals. Use of English and Spanish in the home was assessed via parental report. Multilevel modeling, including parent education as a covariate, revealed that children from bilingual homes lagged 6 months to 1 year behind monolingual children in English vocabulary growth. The size of the lag was related to the relative amount of English use in the home, but the relation was not linear. Increments in English use conferred the greatest benefit most among homes with already high levels of English use. These homes also were likely to have 1 parent who was a native English speaker. Bilingual children showed stronger growth in English than in Spanish. Bilingual children can lag 6 months to 1 year behind monolingual children in normal English language development. Such lags may not necessarily signify clinically relevant delay if parents report that children also have skills in the home language. Shorter lags are associated with 2 correlated factors: more English exposure and more exposure from native English speakers. Early exposure to Spanish in the home does not guarantee acquisition of Spanish. Copyright © 2017 Elsevier Inc. All rights reserved.
Riveiro-Alvarez, Rosa; Lopez-Martinez, Miguel-Angel; Zernant, Jana; Aguirre-Lamban, Jana; Cantalapiedra, Diego; Avila-Fernandez, Almudena; Gimenez, Ascension; Lopez-Molina, Maria-Isabel; Garcia-Sandoval, Blanca; Blanco-Kelly, Fiona; Corton, Marta; Tatu, Sorina; Fernandez-San Jose, Patricia; Trujillo-Tiebas, Maria-Jose; Ramos, Carmen; Allikmets, Rando; Ayuso, Carmen
2013-11-01
To provide a comprehensive overview of all detected mutations in the ABCA4 gene in Spanish families with autosomal recessive retinal disorders, including Stargardt's disease (arSTGD), cone-rod dystrophy (arCRD), and retinitis pigmentosa (arRP), and to assess genotype-phenotype correlation and disease progression in 10 years by considering the type of variants and age at onset. Case series. A total of 420 unrelated Spanish families: 259 arSTGD, 86 arCRD, and 75 arRP. Spanish families were analyzed through a combination of ABCR400 genotyping microarray, denaturing high-performance liquid chromatography, and high-resolution melting scanning. Direct sequencing was used as a confirmation technique for the identified variants. Screening by multiple ligation probe analysis was used to detect possible large deletions or insertions in the ABCA4 gene. Selected families were analyzed further by next generation sequencing. DNA sequence variants, mutation detection rates, haplotypes, age at onset, central or peripheral vision loss, and night blindness. Overall, we detected 70.5% and 36.6% of all expected ABCA4 mutations in arSTGD and arCRD patient cohorts, respectively. In the fraction of the cohort where the ABCA4 gene was sequenced completely, the detection rates reached 73.6% for arSTGD and 66.7% for arCRD. However, the frequency of possibly pathogenic ABCA4 alleles in arRP families was only slightly higher than that in the general population. Moreover, in some families, mutations in other known arRP genes segregated with the disease phenotype. An increasing understanding of causal ABCA4 alleles in arSTGD and arCRD facilitates disease diagnosis and prognosis and also is paramount in selecting patients for emerging clinical trials of therapeutic interventions. Because ABCA4-associated diseases are evolving retinal dystrophies, assessment of age at onset, accurate clinical diagnosis, and genetic testing are crucial. We suggest that ABCA4 mutations may be associated with a
Tavera-Tapia, A; Pérez-Cabornero, L; Macías, J A; Ceballos, M I; Roncador, G; de la Hoya, M; Barroso, A; Felipe-Ponce, V; Serrano-Blanch, R; Hinojo, C; Miramar-Gallart, M D; Urioste, M; Caldés, T; Santillan-Garzón, S; Benitez, J; Osorio, A
2017-02-01
There is still a considerable percentage of hereditary breast and ovarian cancer (HBOC) cases not explained by BRCA1 and BRCA2 genes. In this report, next-generation sequencing (NGS) techniques were applied to identify novel variants and/or genes involved in HBOC susceptibility. Using whole exome sequencing, we identified a novel germline mutation in the moderate-risk gene ATM (c.5441delT; p.Leu1814Trpfs*14) in a family negative for mutations in BRCA1/2 (BRCAX). A case-control association study was performed to establish its prevalence in Spanish population, in a series of 1477 BRCAX families and 589 controls further screened, and NGS panels were used for ATM mutational screening in a cohort of 392 HBOC Spanish BRCAX families and 350 patients affected with diseases not related to breast cancer. Although the interrogated mutation was not prevalent in case-control association study, a comprehensive mutational analysis of the ATM gene revealed 1.78% prevalence of mutations in the ATM gene in HBOC and 1.94% in breast cancer-only BRCAX families in Spanish population, where data about ATM mutations were very limited. ATM mutation prevalence in Spanish population highlights the importance of considering ATM pathogenic variants linked to breast cancer susceptibility.
Belz, Regina G; Hurle, Karl
2005-01-26
Benzoxazinoids (Bx) are natural phytotoxins that function as chemical defense compounds in several species. The release of Bx by intact plant roots associated these compounds with root allelopathy in Triticeae species; however, the significance of exudate concentrations of Bx for plant-plant interactions is still a controversial question. A biological screening of 146 cultivars of four Triticeae species (Triticum aestivum L., Triticum durum Desf., Triticum spelta L., and Secale cereale L.) demonstrated a high cultivar dependence to suppress the root growth of Sinapis alba L. by root allelopathy in a dose-response bioassay. Only a few cultivars possessed a marked high or low allelopathic activity, whereby high-performance liquid chromatography-diode array detection analysis of root exudates revealed that these cultivars differed considerably in their ability to exude the two Bx aglucones, DIBOA [2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one] and DIMBOA [2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one]. The total amount of DIBOA and DIMBOA exuded showed a significant correlation to the growth inhibition in bioassay with a statistically estimated contribution to the overall allelopathic effect of 48-72%. In a bioassay with pure phytotoxins, Bx concentrations consistent with the amounts quantified in the screening bioassay caused detrimental effects on S. alba and almost reproduced the statistically estimated contribution. The observed causal association between the allelopathic activity under laboratory conditions and the exudate concentrations of Bx suggests that this association might have implications for the interference of Triticeae species in natural plant communities.
ERIC Educational Resources Information Center
Silber, Ellen S., Ed.; Krug, Clara, Ed.
This guide presents essays and curriculum units designed for use by secondary and college teachers of French, German, and Spanish as a foreign language. The first section of the work includes two essays, in French, and eight curriculum units based on the stories of Guy de Maupassant. The second section contains seven curriculum units that…
ERIC Educational Resources Information Center
Fulei-Szanto, Andres
1974-01-01
A description of a contrastive linguistics project in Hungary aiming to augment linguistic theories in the Spanish language and propound theories for scientific and artistic translation. (Text is in Spanish.) (CK)
Semantic and Pragmatic Functions of the Spanish Diminutive in Spanish in Contact with Quechua.
ERIC Educational Resources Information Center
Escobar, Anna Maria
2001-01-01
Presents data from the Spanish of Quechua-Spanish bilinguals that exemplify a contact situation that gives rise to a process called structural interference. Concentrates on the use of the diminutive in the Spanish of speakers of Spanish in the Andes. (Author/VWL)
Validation of 2 Spanish-Language Scales to Assess HIV-Related Stigma in Communities.
Franke, Molly F; Nelson, Adrianne K; Muñoz, Maribel; Cruz, Janeth Santa; Atwood, Sidney; Lecca, Leonid; Shin, Sonya S
2015-01-01
We report the psychometric properties of 2 Spanish-language scales designed to measure (1) opinions about HIV in the community and particularly among health care workers and (2) observed acts of stigma toward people living with HIV/AIDS (PLWHA) by health care workers. The Opinions about HIV Scale included 3 components (policy, avoidance, and empathy) and 9 items, while an adapted version of the HIV/AIDS Stigma Instrument-Nurse, designed to capture acts of stigma, included 2 components (discrimination related to clinical care and refusal to share or exchange food/gifts). Scales demonstrated good reliability and construct validity. Relative to community health workers, treatment supporters were more likely to have stigmatizing opinions related to avoidance and empathy. We offer 2 Spanish-language scales that could be used to identify populations with high levels of stigmatizing opinions and behaviors toward PLWHA. Formal training of health care workers, especially treatment supporters, may raise awareness and reduce stigma toward HIV. © The Author(s) 2014.
How Readable are Spanish-Language Medicaid Applications?
Hansen, Julie S.; DeVoe, Jennifer E.
2015-01-01
Nationally, Hispanics comprise nearly one-quarter of all non-elderly Medicaid recipients. We evaluated readability, layout characteristics, and document complexity of state-issued Spanish-language Medicaid enrollment applications. We located and analyzed Internet-based Spanish enrollment applications from 37 states and the District of Columbia. We calculated the readability of each Medicaid enrollment application “Signature” page using the Spanish Lexile Analyzer. We assessed application layout characteristics utilizing the User-Friendliness Tool, and we evaluated document complexity using the PMOSE/IKIRSCH scale. The average Lexile score estimated an 11th–12th grade reading level (M = 1184, SD = 192) for “Signature” pages of enrollment applications. Most applications used small font size and lacked adequate white space. Document complexity ranged from level 3 (moderate) to level 5 (very high); the majority of applications ranked at level 4 (high). Spanish-language Medicaid enrollment applications should be revised to adhere to low-literacy guidelines, which may improve the accessibility of Medicaid coverage for eligible Spanish-speaking families. PMID:21213122
Kolodziejczyk, Julia K; Norman, Gregory J; Barrera-Ng, Angelica; Dillon, Lindsay; Marshall, Simon; Arredondo, Elva; Rock, Cheryl L; Raab, Fred; Griswold, William G; Sullivan, Mark; Patrick, Kevin
2013-11-06
Little is known about the feasibility and acceptability of tailored text message based weight loss programs for English and Spanish-language speakers. This pilot study evaluated the feasibility, acceptability, and estimated impact of a tailored text message based weight loss program for English and Spanish-language speakers. The purpose of this pilot study was to inform the development of a full-scale randomized trial. There were 20 overweight or obese participants (mean age 40.10, SD 8.05; 8/20, 40% male; 9/20, 45% Spanish-speakers) that were recruited in San Diego, California, from March to May 2011 and evaluated in a one-group pre/post clinical trial. For 8 weeks, participants received and responded to 3-5 text messages daily sent from a fully automated text messaging system. They also received printed weight loss materials and brief 10-15 minute weekly counseling calls. To estimate the impact of the program, the primary outcome was weight (kg) measured during face-to-face measurement visits by trained research staff. Pre and post differences in weight were analyzed with a one-way repeated measures analysis of variance. Differences by language preference at both time points were analyzed with t tests. Body mass index and weight management behaviors also were examined. Feasibility and acceptability were determined by recruitment success, adherence (ie, percentage of replies to interactive text messages and attrition), and participant satisfaction. Participants who completed the final assessment (N=18) decreased body weight by 1.85 kg (F1,17=10.80, P=.004, CI∆ 0.66-3.03, η(2)=0.39). At both time points, there were no differences in weight by language preference. Participants responded to 88.04% (986/1120) of interactive text messages, attrition rate was 10% (2/20), and 94% (19/20) of participants reported satisfaction with the program. This fully automated text message based weight program was feasible with English and Spanish-speakers and may have promoted
21 CFR 290.6 - Spanish-language version of required warning.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Spanish-language version of required warning. 290... (CONTINUED) DRUGS: GENERAL CONTROLLED DRUGS General Provisions § 290.6 Spanish-language version of required... of this drug to any person other than the patient for whom it was prescribed.” The Spanish version of...
Validation of a Spanish-language version of the ADHD Rating Scale IV in a Spanish sample.
Vallejo-Valdivielso, M; Soutullo, C A; de Castro-Manglano, P; Marín-Méndez, J J; Díez-Suárez, A
2017-07-14
The purpose of this study is to validate a Spanish-language version of the 18-item ADHD Rating Scale-IV (ADHD-RS-IV.es) in a Spanish sample. From a total sample of 652 children and adolescents aged 6 to 17 years (mean age was 11.14±3.27), we included 518 who met the DSM-IV-TR criteria for ADHD and 134 healthy controls. To evaluate the factorial structure, validity, and reliability of the scale, we performed a confirmatory factor analysis (CFA) using structural equation modelling on a polychoric correlation matrix and maximum likelihood estimation. The scale's discriminant validity and predictive value were estimated using ROC (receiver operating characteristics) curve analysis. Both the full scale and the subscales of the Spanish-language version of the ADHD-RS-IV showed good internal consistency. Cronbach's alpha was 0.94 for the full scale and ≥ 0.90 for the subscales, and ordinal alpha was 0.95 and ≥ 0.90, respectively. CFA showed that a two-factor model (inattention and hyperactivity/impulsivity) provided the best fit for the data. ADHD-RS-IV.es offered good discriminant ability to distinguish between patients with ADHD and controls (AUC=0.97). The two-factor structure of the Spanish-language version of the ADHD-RS-IV (ADHD-RS-IV.es) is consistent with those of the DSM-IV-TR and DSM-5 as well as with the model proposed by the author of the original scale. Furthermore, it has good discriminant ability. ADHD-RS-IV.es is therefore a valid and reliable tool for determining presence and severity of ADHD symptoms in the Spanish population. Copyright © 2017 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.
SCDC Spanish Curricula Units. Language Arts, Unit 6, Grade 2, Teacher's Guide.
ERIC Educational Resources Information Center
Spanish Curricula Development Center, Miami Beach, FL.
Language arts instructional and assessment activities for grade two are described in this teacher's guide to the language arts strand of unit six. Focus, objective and materials for each activity are given in English and Spanish, with teacher instructions only in Spanish. This strand includes a continuation of the basic activities of past units:…
The Spanish participation in the SKA
NASA Astrophysics Data System (ADS)
Verdes-Montenegro, L.; Garrido, J.; González-García, M.
2017-03-01
The Square Kilometre Array (SKA) will be a radio interferometer aiming to answer fundamental questions in Astrophysics, Fundamental Physics, and Astrobiology. It will be composed of thousands of antennas distributed over distances of more than 3000 kilometres on both Africa and Australia. The SKA has been recently identified as a Landmark Project in the European Strategy Forum on Research Infrastructures (ESFRI) roadmap. Spain has been participating in SKA-related activities since the 1990s, coordinated since 2011 by the Instituto de Astrofísica de Andalucía (IAA-CSIC). Up to now, 21 researchers participate in 7 out of the 11 main SKA Science Working Groups, and a total of 119 researchers from 40 Spanish centres have participated in the Spanish SKA White Book, published in 2015. From a technological point of view, more than 20 research centres and companies are contributing to the design of the SKA as part of 7 international consortia. The Spanish contribution was estimated in 2M euro (2014), officially recognized by the SKA Organisation Director General in a letter to the Spanish Ministry of Economy and Competitiveness. In addition, the Spanish Astronomy Infrastructures Network (RIA from its Spanish initials) issued a recommendation on the interest of the scientific community and industry that Spain explores the possibility to join the SKA project as Full Member before the construction phase starts. In December 2015, the Spanish Secretary of State of Research, Development and Innovation sent a letter to the SKA Organisation Director General proposing to establish a dialogue in order to explore scenarios for Spain to join the SKA, what constitutes a further motivation for the Spanish community to continue its efforts.
Early lexical development in Spanish-speaking infants and toddlers.
Jackson-Maldonado, D; Thal, D; Marchman, V; Bates, E; Gutierrez-Clellen, V
1993-10-01
This paper describes the early lexical development of a group of 328 normal Spanish-speaking children aged 0;8 to 2;7. First the development and structure of a new parent report instrument, Inventario del Desarollo de Habilidades Communicativas is described. Then five studies carried out with the instrument are presented. In the first study vocabulary development of Spanish-speaking infants and toddlers is compared to that of English-speaking infants and toddlers. The English data were gathered using a comparable parental report, the MacArthur Communicative Development Inventories. In the second study the general characteristics of Spanish language acquisition, and the effects of various demographic factors on that process, are examined. Study 3 examines the differential effects of three methods of collecting the data (mail-in, personal interview, and clinic waiting room administration). Studies 4 and 5 document the reliability and validity of the instrument. Results show that the trajectories of development are very similar for Spanish- and English-speaking children in this age range, that children from varying social groups develop similarly, and that mail-in and personal interview administration techniques produce comparable results. Inventories administered in a medical clinic waiting room, on the other hand, produced lower estimates of toddler vocabulary than the other two models.
Experience with a Spanish-language laparoscopy website.
Moreno-Sanz, Carlos; Seoane-González, Jose B
2006-02-01
Although there are no clearly defined electronic tools for continuing medical education (CME), new information technologies offer a basic platform for presenting training content on the internet. Due to the shortage of websites about minimally invasive surgery in the Spanish language, we set up a topical website in Spanish. This study considers the experience with the website between April 2001 and January 2005. To study the activity of the website, the registry information was analyzed descriptively using the log files of the server. To study the characteristics of the users, we searched the database of registered users. We found a total of 107,941 visits to our website and a total of 624,895 page downloads. Most visits to the site were made from Spanish-speaking countries. The most frequent professional profile of the registered users was that of general surgeon. The development, implementation, and evaluation of Spanish-language CME initiatives over the internet is promising but presents challenges.
Lai, Hung-Wen; Liu, Liang-Chih; Ouyang, Fu; Yao, Chung-Chin; Jan, Hsiang-Chun; Chang, Ya-Herng; Tu, Chi-Wen; Chen, Dar-Ren; Cheng, Tsui-Fen; Tzeng, Yen-Dun; Hsu, Huan-Ming; Yeh, Ming-Hsin; Wu, Yao-Chung; Yang, Po-Sheng; Lam, Hung-Bun; Hou, Ming-Feng; Chen, Fang-Ming
2017-01-01
In this multi-center study, we report the patient selection criteria for and preliminary oncologic outcomes associated with intraoperative radiotherapy (IORT) delivered by the Xoft Axxent® eBx® system for early-stage breast cancer in Taiwan. Patients with early breast cancer in Taiwan received breast conserving surgery and received IORT with Xoft Axxent® eBx® System during 2013-2015 was search from database of Taiwan IORT study cooperative group (T-IORTSCG). Patients' clinicopathologic characteristics and early post-operative results were collected and reported. During the study period, 26 hospitals in Taiwan performed a total of 261 Xoft IORT procedures for breast cancer. The mean age of them was 52.9 ± 9.8 years (37-72), and tumor size was 1.5 ± 0.8 cm (0.1-4.2 cm) for invasive cancer and 1.2 ± 0.8 cm (range, 0.2-3.0 cm) for ductal carcinoma in situ (DCIS) lesions. Lymph node metastasis was found in 6 (2.3%) patients. The patients received IORT in Taiwan differed markedly from those used in the ELIOT and TARGIT-A studies. Specifically, patients selected for IORT in Taiwan tended to be younger, their tumors tended to be larger and the prevalence of lymph node metastasis tended to be lower. Among these 261 patients, 8 (3.1%) patients required whole breast radiotherapy. During a mean follow up of 15.6 months, locoregional recurrence was observed in 2 (0.8%) patients. In real world experience, patients received IORT differed quite significantly with criteria formulated by trials. The preliminary results of IORT in Taiwan showed it is well acceptable by patients and clinicians.
Lee, Shoou-Yih Daniel; Stucky, Brian D; Lee, Jessica Y; Rozier, R Gary; Bender, Deborah E
2010-01-01
Objective The intent of the study was to develop and validate a comparable health literacy test for Spanish-speaking and English-speaking populations. Study Design The design of the instrument, named the Short Assessment of Health Literacy—Spanish and English (SAHL-S&E), combined a word recognition test, as appearing in the Rapid Estimate of Adult Literacy in Medicine (REALM), and a comprehension test using multiple-choice questions designed by an expert panel. We used the item response theory (IRT) in developing and validating the instrument. Data Collection Validation of SAHL-S&E involved testing and comparing the instrument with other health literacy instruments in a sample of 201 Spanish-speaking and 202 English-speaking subjects recruited from the Ambulatory Care Center at the University of North Carolina Healthcare System. Principal Findings Based on IRT analysis, 18 items were retained in the comparable test. The Spanish version of the test, SAHL-S, was highly correlated with other Spanish health literacy instruments, Short Assessment of Health Literacy for Spanish-Speaking Adults (r=0.88, p<.05) and the Spanish Test of Functional Health Literacy in Adults (TOFHLA) (r=0.62, p<.05). The English version, SAHL-E, had high correlations with REALM (r=0.94, p<.05) and the English TOFHLA (r=0.68, p<.05). Significant correlations were found between SAHL-S&E and years of schooling in both Spanish- and English-speaking samples (r=0.15 and 0.39, respectively). SAHL-S&E displayed satisfactory reliability of 0.80 and 0.89 in the Spanish- and English-speaking samples, respectively. IRT analysis indicated that the SAHL-S&E score was highly reliable for individuals with a low level of health literacy. Conclusions The new instrument, SAHL-S&E, has good reliability and validity. It is particularly useful for identifying individuals with low health literacy and could be used to screen for low health literacy among Spanish and English speakers. PMID:20500222
Validation of a Spanish version of the Revised Fibromyalgia Impact Questionnaire (FIQR)
2013-01-01
Background The Revised version of the Fibromyalgia Impact Questionnaire (FIQR) was published in 2009. The aim of this study was to prepare a Spanish version, and to assess its psychometric properties in a sample of patients with fibromyalgia. Methods The FIQR was translated into Spanish and administered, along with the FIQ, the Hospital Anxiety Depression Scale (HADS), the 36-Item Short-Form Health Survey (SF-36), and the Brief Pain Inventory (BPI), to 113 Spanish fibromyalgia patients. The administration of the Spanish FIQR was repeated a week later. Results The Spanish FIQR had high internal consistency (Cronbach’s α was 0.91 and 0.95 at visits 1 and 2 respectively). The test-retest reliability was good for the FIQR total score and its function and symptoms domains (intraclass correlation coefficient (ICC > 0.70), but modest for the overall impact domain (ICC = 0.51). Statistically significant correlations (p < 0.05) were also found between the FIQR and the FIQ scores, as well as between the FIQR scores and the remaining scales’ scores. Conclusions The Spanish version of the FIQR has a good internal consistency and our findings support its validity for assessing fibromyalgia patients. It might be a valid instrument to apply in clinical and investigational grounds. PMID:23915386
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-01
... C2 Options Exchange, Inc. (``C2''). The text of the proposed rule change is available on the Exchange... Rules in order to recoup costs applicable to the C2 Options Exchange, Inc. (``C2'') that the Exchange... NASDAQ OMX PHLX LLC (``PHLX'') and NASDAQ OMX BX, Inc. (``BX Options'') and a $0.11 per contract fixed...
ERIC Educational Resources Information Center
Hardin, Karol
2012-01-01
Demand for medical Spanish courses has grown with the rising needs of Spanish-speaking patients in the United States, but while there is no shortage of beginning medical Spanish textbooks, very few target the intermediate level. This article examines eighteen medical Spanish texts published in the last twenty years with respect to seven factors:…
The Effect of Exposure on Syntactic Parsing in Spanish-English Bilinguals
ERIC Educational Resources Information Center
Dussias, Paola E.; Sagarra, Nuria
2007-01-01
An eye tracking experiment examined how exposure to a second language (L2) influences sentence parsing in the first language. Forty-four monolingual Spanish speakers, 24 proficient Spanish-English bilinguals with limited immersion experience in the L2 environment and 20 proficient Spanish-English bilinguals with extensive L2 immersion experience…
A Marketing Strategy for Spanish for Business.
ERIC Educational Resources Information Center
Grosse, Christine Uber
The development of a marketing strategy for business Spanish courses by means of situational analysis is described. The planner of marketing strategy must consider demand for a course, institutional acceptance, and financial support. A survey of 508 universities revealed a low level of demand for business Spanish which could potentially be…
Stephens, Camilla; Moreno-Casares, Antonia; López-Nevot, Miguel-Ángel; García-Cortés, Miren; Medina-Cáliz, Inmaculada; Hallal, Hacibe; Soriano, German; Roman, Eva; Ruiz-Cabello, Francisco; Romero-Gomez, Manuel; Lucena, M Isabel; Andrade, Raúl J
2016-01-01
Natural killer cells are an integral part of the immune system and represent a large proportion of the lymphocyte population in the liver. The activity of these cells is regulated by various cell surface receptors, such as killer Ig-like receptors (KIR) that bind to human leukocyte antigen (HLA) class I ligands on the target cell. The composition of KIR receptors has been suggested to influence the development of specific diseases, in particularly autoimmune diseases, cancer and reproductive diseases. The role played in idiosyncratic drug-induced liver injury (DILI) is currently unknown. In this study, we examined KIR gene profiles and HLA class I polymorphisms in amoxicillin-clavulanate (AC) DILI patients in search for potential risk associations. One hundred and two AC DILI patients and 226 controls were genotyped for the presence or absence of 16 KIR loci, including the two pseudogenes 2DP1 and 3DP1. No significant differences were found in the distribution of individual KIRs between patients and controls, which were comparable to previously reported KIR data from ethnically similar cohorts. The 21.6 and 21.2% of the patients and controls, respectively, were homozygous haplotype A carriers, while 78.4 and 78.8%, respectively, contained at least one B haplotype (Bx). The genotypes translated into 27 (AC DILI) and 46 (controls) different gene profiles, with 19 being present in both groups. The most frequent Bx gene profile containing KIRs 2DS2, 2DL2, 2DL3, 2DP1, 2DL1, 3DL1, 2DS4, 3DL2, 3DL3, 2DL4, and 3PD1 was present in 16% of the DILI patients and 14% of the controls. The distribution of HLA class I epitopes did not differ significantly between AC DILI patients and controls. The most frequent receptor-ligand combinations in the DILI patients were 2DL3 + epitope C1 (67%) and 3DL1 + Bw4 motif (67%), while 2DL1 + epitope C2 (69%) and 3DL1 + Bw4 motif (69%) predominated in the controls. This is to our knowledge the first analysis of KIR receptor-HLA ligand
Stephens, Camilla; Moreno-Casares, Antonia; López-Nevot, Miguel-Ángel; García-Cortés, Miren; Medina-Cáliz, Inmaculada; Hallal, Hacibe; Soriano, German; Roman, Eva; Ruiz-Cabello, Francisco; Romero-Gomez, Manuel; Lucena, M. Isabel; Andrade, Raúl J.
2016-01-01
Natural killer cells are an integral part of the immune system and represent a large proportion of the lymphocyte population in the liver. The activity of these cells is regulated by various cell surface receptors, such as killer Ig-like receptors (KIR) that bind to human leukocyte antigen (HLA) class I ligands on the target cell. The composition of KIR receptors has been suggested to influence the development of specific diseases, in particularly autoimmune diseases, cancer and reproductive diseases. The role played in idiosyncratic drug-induced liver injury (DILI) is currently unknown. In this study, we examined KIR gene profiles and HLA class I polymorphisms in amoxicillin-clavulanate (AC) DILI patients in search for potential risk associations. One hundred and two AC DILI patients and 226 controls were genotyped for the presence or absence of 16 KIR loci, including the two pseudogenes 2DP1 and 3DP1. No significant differences were found in the distribution of individual KIRs between patients and controls, which were comparable to previously reported KIR data from ethnically similar cohorts. The 21.6 and 21.2% of the patients and controls, respectively, were homozygous haplotype A carriers, while 78.4 and 78.8%, respectively, contained at least one B haplotype (Bx). The genotypes translated into 27 (AC DILI) and 46 (controls) different gene profiles, with 19 being present in both groups. The most frequent Bx gene profile containing KIRs 2DS2, 2DL2, 2DL3, 2DP1, 2DL1, 3DL1, 2DS4, 3DL2, 3DL3, 2DL4, and 3PD1 was present in 16% of the DILI patients and 14% of the controls. The distribution of HLA class I epitopes did not differ significantly between AC DILI patients and controls. The most frequent receptor-ligand combinations in the DILI patients were 2DL3 + epitope C1 (67%) and 3DL1 + Bw4 motif (67%), while 2DL1 + epitope C2 (69%) and 3DL1 + Bw4 motif (69%) predominated in the controls. This is to our knowledge the first analysis of KIR receptor-HLA ligand
[Nursing in the movies: its image during the Spanish Civil War].
Siles González, J; García Hernández, E; Cibanal Juan, L; Gallardo Frías, Y; Lillo Crespo, M
1998-12-01
The cinema had carried out a determining role in the development of stereotypes and in a wide gamut of models related to real life situations. The objective of this analysis is to determine the influence cinema had on the image of nurses during the Spanish Civil War from 1936-1939. These are the initial hypotheses: the role of Spanish nurses during the civil war was reflected by both sides in their respective movie productions; and the image of nurses shown in these films, on both sides, presents a conflicting role concept for women in society. Following strategies developed by specialists in film analysis (Bondwell 1995, Uneso 1995, Carmona 1991) a total of 453 movie productions, 360 on the republican side and 93 on the national side, were reviewed. These films were listed in the Spanish National Films Library records. After analyzing the Spanish cinema productions during the Spanish Civil War, data relating to 453 films were identified. The genre included documents, news programs and fiction movies. 77 were produced in 1936, 235 in 1937, 102 in 1938 and 39 in 1939. A tremendous difference exists between the republican productions, 79% of the total, and the national productions. By genres, the types produced on the republican side were: in 1936, 53 documentals, 4 news programs and 9 fiction films; in 1937, 186 documentals, 5 news programs and 19 fiction films; in 1938, 72 documentals, 1 news programs and 2 fiction films; in 1939, 2 documentals and 2 fiction films. On the national side, their productions were: in 1936, 10 documentals and 1 fiction film; in 1937, 22 documentals, 2 news programs and 1 fiction film; in 1938, 19 documentals and 3 news programs; in 1939, 29 documentals and 6 fiction films. During the Spanish Civil War, movies produced by both sides made an effort to reflect their ideal woman as a stereotypical ideal nurse. This ideal nurse showed the values, ideas, aesthetics and prejudices each side held in the war.
English-Speaking and Spanish-Speaking Domestic Violence Perpetrators: An MMPI-2 Assessment
ERIC Educational Resources Information Center
Scott, Ronald L.; Flowers, John V.; Bulnes, Alejandro; Olmsted, Eileen; Carbajal-Madrid, Pedro
2009-01-01
The use of assessments to characterize domestic violence perpetrators continues to develop with an emphasis on increasing the effectiveness of domestic violence interventions. The present study examines and compares Minnesota Multiphasic Personality Inventory (MMPI)-2 responses from 41 English-speaking and 48 Spanish-speaking men who were in…
Murcia, J A M; Gimeno, E C; Camacho, A M
2007-09-01
The aim of this study is the validation in the Spanish context of the Behavioural Regulation in Exercise Questionnaire-2 (BREQ-2) scale, developed by Markland et al., from the point of view of the self-determination theory and to compare the effect of gender, age and exercise duration and mode. For the validation of the instrument, two studies were carried out (n=250 and n=311) with a total sample formed of 561 adults in the metropolitan area of the city of Murcia, Spain, who do non-competitive sport and physical activities. They were given the adaptation of the questionnaire BREQ-2 by Markland et al. to fill in. After an exploratory factor analysis and a confirmatory factor analysis, an adaptation of the scale was obtained with 18 items and 5 factors with acceptable reliability coefficients and a total variance explained of 68.8%. The two highest assessed forms of behavioral regulation were intrinsic and identified, with the women showing more intrinsic regulation. Those that exercised for less time were the ones that showed higher levels of amotivation and the older people showed a greater tendency to identified regulation. The BREQ-2 scale has all the required conditions, as far as reliability and validity criteria are concerned, to be used in the Spanish context in different areas of physical activity.
Spanish in California: A Historical Perspective.
ERIC Educational Resources Information Center
Sapiens, Alexander
1979-01-01
Presents an historical survey of Spanish language and educational policy in California highlighting those factors which may account for the present survival of the Spanish language. The role of education as an instrument of societal integration is examined in terms of its impact upon the Chicanos' language and educational achievement. (JMF)
Galbany-Estragués, Paola; Nelson, Sioban
2016-11-01
After the financial crisis of 2008, increasing numbers of nurses from Spain are going abroad to work. To examine the health and workforce policy trends in Spain between 2009 and 2014 and to analyze their correlation with the migration of nurses. Single embedded case study. We examined data published by: Health Statistics, Organization for Economic Cooperation and Development (1996 to 2013); Ministry of Education, Culture and Sports (2006 to 2013); Ministry of Employment and Social Security (2009 to 2014); Ministry of Health, Social Services and Equality (1997 to 2014); and National Institute of Statistics (1976 to 2014). In addition to reviewing the scholarly literature on the topic in Spanish and English, we also examined Spanish mobility laws and European directives. We used the Organization for Economic Cooperation and Development definition of "professionally active nurses" which defines practising nurses and other nurses as those for whom their education is a prerequisite for employment as a nurse. Moreover, we used the term "nursing graduate" as defined by Spanish Ministry of Education to describe those who have obtained a recognized qualification in nursing in a given year, the term "registered nurses" is defined by Spanish law as nurses registered in the Nurses Associations and "unemployed nurses" are those without work and registered as seeking employment. A transformation of the Spanish health system has reduced the number of employed nurses per capita since 2010. Moreover, reductions in public spending, labour market reforms and widespread unemployment have affected nurses in two ways: first by increasing the number of applicants per vacancy between 2009 and 2013, and second, by an increase in casual positions. However, despite the poor job market and decreasing job security, the number of registered nurses and nursing graduates in Spain per year has continued to grow, increasing the pressure on the labour market. Spain is transforming from a stable
Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-β Signaling
Fullerton, Paul T.; Creighton, Chad J.
2015-01-01
Pancreatic ductal adenocarcinoma (PDAC) is the fourth-leading cause of cancer death in the United States. The TGF-β signaling protein SMAD family member 4 is lost in 60% of PDAC, and this has been associated with poorer prognosis. However, the mechanisms by which SMAD4 loss promotes PDAC development are not fully understood. We expressed SMAD4 in human PDAC cell lines BxPC3 and CFPAC1 by selection of stable clones containing an inducible SMAD4 tetracycline inducible expression system construct. After 24 hours of SMAD4 expression, TGF-β signaling-dependent G1 arrest was observed in BxPC3 cells with an increase in the G1 phase fraction from 48.9% to 71.5%. Inhibition of cyclin-dependent kinase inhibitor 1A by small interfering RNA eliminated the antiproliferative effect, indicating that up-regulation of cyclin-dependent kinase inhibitor 1A/p21 by TGF-β signaling is necessary for the phenotype. SMAD4 expression had no impact on invasion in BxPC3 cells, but reduced migration. Microarray analysis of gene expression at 8, 24, and 48 hours after SMAD4 expression characterized the regulatory impact of SMAD4 expression in a SMAD4-null PDAC cell line and identified novel targets of TGF-β signaling. Among the novel TGF-β targets identified are anthrax toxin receptor 2 (3.58× at 8 h), tubulin, β-3 class III (7.35× at 8 h), cell migration inducing protein, hyaluronan binding (8.07× at 8 h), IL-1 receptor-like 1 (0.403× at 8 h), regulator of G protein signaling 4 (0.293× at 8 h), and THAP domain containing 11 (0.262× at 8 h). The gene expression changes we observed upon restoration of TGF-β signaling provide numerous new targets for future investigations into PDAC biology and progression. PMID:26284758
7 CFR 51.2730 - U.S. No. 1 Spanish.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. No. 1 Spanish. 51.2730 Section 51.2730... STANDARDS) United States Standards for Grades of Shelled Spanish Type Peanuts Grades § 51.2730 U.S. No. 1 Spanish. “U.S. No. 1 Spanish” consists of shelled Spanish type peanut kernels which are whole and free...
Xu, Ya-Ming; Bashyal, Bharat P; Liu, Mangping X; Espinosa-Artiles, Patricia; U'Ren, Jana M; Arnold, A Elizabeth; Gunatilaka, A A Leslie
2015-10-01
Two new metabolites, 6-oxo-12-norcytochalasin D (1) and 4,5-di-isobutyl-2(1H)-pyrimidinone (2), together with seven known metabolites, cytochalasins D (3), Q (4), and N (5), 12-hydroxyzygosporin G (6), heptelidic acid chlorohydrin (7), (+)-heptelidic acid (8), and trichoderonic acid A (9), were isolated from Xylariaceae sp. FL0390, a fungal endophyte inhabiting Spanish moss, Tillandsia usneoides. Metabolite 1 is the first example of a 12-norcytochalasin. All metabolites, except 2 and 9, showed cytotoxic activity in a panel of five human tumor cell lines with IC50S of 0.2-5.0 μM.
Prevalence of 2314delG mutation in Spanish patients with Usher syndrome type II (USH2).
Beneyto, M M; Cuevas, J M; Millán, J M; Espinós, C; Mateu, E; González-Cabo, P; Baiget, M; Doménech, M; Bernal, S; Ayuso, C; García-Sandoval, B; Trujillo, M J; Borrego, S; Antiñolo, G; Carballo, M; Nájera, C
2000-06-01
The Usher syndrome (USH) is a group of autosomal recessive diseases characterized by congenital sensorineural hearing loss and retinitis pigmentosa. Three clinically distinct forms of Usher syndrome have so far been recognized and can be distinguished from one another by assessing auditory and vestibular function. Usher syndrome type II (USH2) patients have congenital moderate-to-severe nonprogressive hearing loss, retinitis pigmentosa, and normal vestibular function. Genetic linkage studies have revealed genetic heterogeneity among the three types of USH, with the majority of USH2 families showing linkage to the USH2A locus in 1q41. The USH2A gene (MIM 276901) has been identified: three mutations, 2314delG, 2913delG, and 4353-54delC, were initially reported in USH2A patients, the most frequent of which is the 2314delG mutation. It has been reported that this mutation can give rise to typical and atypical USH2 phenotypes. USH2 cases represent 62% of all USH cases in the Spanish population, and 95% of these cases have provided evidence of linkage to the USH2A locus. In the present study, the three reported mutations were analyzed in 59 Spanish families with a diagnosis of USH type II. The 2314delG was the only mutation identified in our population: it was detected in 25% of families and 16% of USH2 chromosomes analyzed. This study attempts to estimate the prevalence of this common mutation in a homogeneous Spanish population.
Effectiveness of a spanish language clinic for Hispanic youth with type 1 diabetes.
Palau-Collazo, Miladys M; Rose, Paulina; Sikes, Kristin; Kim, Grace; Benavides, Valeria; Urban, Andrea; Weinzimer, Stuart A; Tamborlane, William V
2013-01-01
A pilot study was undertaken to determine whether establishment of a Spanish Language Diabetes Clinic (SLDC) for Spanish-speaking families conducted by a team of Spanish-speaking, Hispanic and nonHispanic clinicians provides a means to improve control of type 1 diabetes (T1D). The first 21 Hispanic pediatric patients with T1D who enrolled in the SLDC were matched to 21 Hispanic patients treated in the English Language Diabetes Clinic (ELDC) based on age and duration of diabetes. The two groups did not differ significantly with respect to gender, body mass index (BMI), or glycated hemoglobin (HbA1c). Patients in both groups were followed for 12 months. The mean (± standard deviation) baseline glycated hemoglobin (HbA1c) level in the SLDC group (8.4 ± 1.0%) was similar to that in the ELDC group (8.6 ± 1.4%, P = .83). HbA1c levels fell by 0.5 ± 1.0% (P = .01) during the year following enrollment in the SLDC but did not change significantly from baseline during the year of follow-up in the ELDC group (decrease of 0.2 ± 0.9%, P = .1). At the start of the study, only 5 patients (23%) in the SLDC group and 7 patients (33%) in the ELDC group met the ≤7.5% target HbA1c level. After 1 year, 10 of the SLDC patients (48%) and 4 of ELDC patients (19%) had HbA1c levels ≤7.5% (P = .01). Our preliminary findings support the hypothesis that overcoming language barriers by the establishment of a SLDC can be an effective means of improving metabolic control in youth with T1D in Hispanic families with limited English language skills.
[Immunisation schedule of the Spanish Association of Paediatrics: 2016 recommendations].
Moreno-Pérez, D; Álvarez García, F J; Arístegui Fernández, J; Cilleruelo Ortega, M J; Corretger Rauet, J M; García Sánchez, N; Hernández Merino, A; Hernández-Sampelayo Matos, T; Merino Moína, M; Ortigosa del Castillo, L; Ruiz-Contreras, J
2016-01-01
The Advisory Committee on Vaccines of the Spanish Association of Paediatrics (CAV-AEP) annually publishes the immunisation schedule which, in our opinion, estimates optimal for children resident in Spain, considering available evidence on current vaccines. We acknowledge the effort of the Ministry of Health during the last year in order to optimize the funded unified Spanish vaccination schedule, with the recent inclusion of pneumococcal and varicella vaccination in early infancy. Regarding the funded vaccines included in the official unified immunization schedule, taking into account available data, CAV-AEP recommends 2+1 strategy (2, 4 and 12 months) with hexavalent (DTPa-IPV-Hib-HB) vaccines and 13-valent pneumococcal conjugate vaccine. Administration of Tdap and poliomyelitis booster dose at the age of 6 is recommended, as well as Tdap vaccine for adolescents and pregnant women, between 27-36 weeks gestation. The two-dose scheme should be used for MMR (12 months and 2-4 years) and varicella (15 months and 2-4 years). Coverage of human papillomavirus vaccination in girls aged 11-12 with a two dose scheme (0, 6 months) should be improved. Information for male adolescents about potential beneficial effects of this immunisation should be provided as well. Regarding recommended unfunded immunisations, CAV-AEP recommends the administration of meningococcal B vaccine, due to the current availability in Spanish communitary pharmacies, with a 3+1 scheme (3, 5, 7 and 13-15 months). CAV-AEP requests the incorporation of this vaccine in the funded unified schedule. Vaccination against rotavirus is recommended in all infants. Annual influenza immunisation and vaccination against hepatitis A are indicated in population groups considered at risk. Copyright © 2015 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.
Nájera, Carmen; Beneyto, Magdalena; Blanca, José; Aller, Elena; Fontcuberta, Ana; Millán, José María; Ayuso, Carmen
2002-07-01
Usher syndrome is an autosomal recessive disorder characterized by congenital hearing impairment and retinitis pigmentosa. Three clinical types are known (USH1, USH2 and USH3), and there is an extensive genetic heterogeneity, with at least ten genes implicated. The most frequently mutated genes are MYO7A, which causes USH1B, and usherin, which causes USH2A. We carried out a mutation analysis of these two genes in the Spanish population. Analysis of the MYO7A gene in patients from 30 USH1 families and sporadic cases identified 32% of disease alleles, with mutation Q821X being the most frequent. Most of the remaining variants are private mutations. With regard to USH2, mutation 2299delG was detected in 25% of the Spanish patients. Altogether the mutations detected in USH2A families account for 23% of the disease alleles. Copyright 2002 Wiley-Liss, Inc.
A Responsive, Integrative Spanish Curriculum at UNC Charlotte
ERIC Educational Resources Information Center
Doyle, Michael S.
2010-01-01
The Spanish program at UNC Charlotte is timely and responsive because it is designed to meet documented societal (job market) needs in today's and tomorrow's global village and economy by providing graduates with strong specialties in English-Spanish translating and in business Spanish. It is integrative in that it does so while maintaining its…
Transnational Spanish Language Project.
ERIC Educational Resources Information Center
Gavillan, Eva; And Others
The Transnational Spanish Language Project curriculum is a set of instructional materials designed to enhance intercultural business communication between North American and Spanish American cultures. The curriculum covers three areas: office procedures; banking; and import/export business. Lessons, all in Spanish, are intended for…
The Dimensionality of Spanish in Young Spanish-English Dual-Language Learners
ERIC Educational Resources Information Center
Journal of Speech, Language, and Hearing Research, 2015
2015-01-01
Purpose: This study examined the latent dimensionality of Spanish in young Spanish-English dual-language learners (DLLs). Method: Two hundred eighty-six children participated. In their prekindergarten year, children completed norm-referenced and experimental language measures in Spanish requiring different levels of cognitive processing in both…
Empirical validation of the CRAFFT Abuse Screening Test in a Spanish sample.
Rial, Antonio; Kim-Harris, Sion; Knight, John R; Araujo, Manuel; Gómez, Patricia; Braña, Teresa; Varela, Jesús; Golpe, Sandra
2018-01-15
The CRAFFT Substance Abuse Screening Instrument, developed by the Center for Adolescents Substance Abuse Research (CeASAR) (Knight et al., 1999), is a screening tool for high-risk alcohol and drug risk consumption designed for use with adolescents. Since its publication it has been the subject of translations and validations in different countries, populations and contexts that have demonstrated its enormous potential. However, there is still no empirical validation study that would ensure its good psychometric performance in Spain. The aim of this paper is to develop an adapted version of the CRAFFT in Spanish and to analyze its psychometric properties in a sample of Spanish adolescents. For this purpose an individual interview was conducted on 312 adolescents aged between 12 and 18 years of age (M = 15.01; SD = 1.83) from the Galician community. The interview included a part of the Adolescent Diagnostic Interview (ADI) and the Problem Oriented Screening Instrument for Teenagers (POSIT). The results obtained, similar to those found in other countries, allow us to report that the Spanish version of the CRAFFT has a good psychometric behaviorproperties. It was found to have a satisfactory internal consistency with a Cronbach’s alpha value of .74. In terms of sensitivity and specificity, values of 74.4% and 96.4% respectively, were obtained and the area under the ROC curve was .946. The Spanish version of the CRAFFT is made available to researchers and professionals in the field of addictive behaviors, so that it can be used with the necessary psychometric guarantees.
Spanish Adaptation and Validation of the Outcome Questionnaire OQ-30.2
Errázuriz, Paula; Opazo, Sebastián; Behn, Alex; Silva, Oscar; Gloger, Sergio
2017-01-01
This study assessed the psychometric properties of a Spanish version of the Shortened Outcome Questionnaire (OQ-30.2, Lambert et al., 2004) validated with a sample of 546 patients in an outpatient mental health clinic and 100 non-clinical adults in Chile. Our results show that this measure has similar normative data to the original measure, with a cutoff score for the Chilean population set at 43.36, and the reliable change index at 14. This Spanish OQ-30.2 has good internal consistency (α = 0.90), has concurrent validity with the Depressive, Anxious, and Somatoform disorders measuring scale (Alvarado and Vera, 1991), and is sensitive to change during psychotherapy. Consistent with previous studies, factorial analyses showed that both, the one-factor solution for a general scale and the three-factor solution containing three theoretical scales yielded poor fit estimates. Overall, our results are similar to past research on the OQ-45 and the OQ-30. The short version has adequate psychometric properties, comparable to those of the OQ-45, but provides a gain in application time that could be relevant in the setting of psychotherapy research with large samples, frequent assessments over time, and/or samples that may require more assistance completing items (e.g., low-literacy). We conclude that this measure will be a valuable instrument for research and clinical practice. PMID:28559857
Perez, Concepcion; Galvez, Rafael; Huelbes, Silvia; Insausti, Joaquin; Bouhassira, Didier; Diaz, Silvia; Rejas, Javier
2007-01-01
Background This study assesses the validity and reliability of the Spanish version of DN4 questionnaire as a tool for differential diagnosis of pain syndromes associated to a neuropathic (NP) or somatic component (non-neuropathic pain, NNP). Methods A study was conducted consisting of two phases: cultural adaptation into the Spanish language by means of conceptual equivalence, including forward and backward translations in duplicate and cognitive debriefing, and testing of psychometric properties in patients with NP (peripheral, central and mixed) and NNP. The analysis of psychometric properties included reliability (internal consistency, inter-rater agreement and test-retest reliability) and validity (ROC curve analysis, agreement with the reference diagnosis and determination of sensitivity, specificity, and positive and negative predictive values in different subsamples according to type of NP). Results A sample of 164 subjects (99 women, 60.4%; age: 60.4 ± 16.0 years), 94 (57.3%) with NP (36 with peripheral, 32 with central, and 26 with mixed pain) and 70 with NNP was enrolled. The questionnaire was reliable [Cronbach's alpha coefficient: 0.71, inter-rater agreement coefficient: 0.80 (0.71–0.89), and test-retest intra-class correlation coefficient: 0.95 (0.92–0.97)] and valid for a cut-off value ≥ 4 points, which was the best value to discriminate between NP and NNP subjects. Discussion This study, representing the first validation of the DN4 questionnaire into another language different than the original, not only supported its high discriminatory value for identification of neuropathic pain, but also provided supplemental psychometric validation (i.e. test-retest reliability, influence of educational level and pain intensity) and showed its validity in mixed pain syndromes. PMID:18053212
Testing Processability Theory in L2 Spanish: Can Readiness or Markedness Predict Development?
ERIC Educational Resources Information Center
Bonilla, Carrie L.
2012-01-01
The goal of this dissertation is to test the five stages of Processability Theory (PT) for second language (L2) learners of Spanish and investigate how instruction can facilitate the development through the stages. PT details five fixed stages in the acquisition of L2 morphosyntax based on principles of speech processing (Levelt, 1989) and modeled…
An Algebraic Approach for Solving Quadratic Inequalities
ERIC Educational Resources Information Center
Mahmood, Munir; Al-Mirbati, Rudaina
2017-01-01
In recent years most text books utilise either the sign chart or graphing functions in order to solve a quadratic inequality of the form ax[superscript 2] + bx + c < 0 This article demonstrates an algebraic approach to solve the above inequality. To solve a quadratic inequality in the form of ax[superscript 2] + bx + c < 0 or in the…
USDA-ARS?s Scientific Manuscript database
Thirty 7/8 Boer × 1/8 Spanish (B) and 29 Spanish (S) wethers were used in a trial with 110 (P1) and 108 d (P2) periods. Six B and 5 S were harvested at the beginning of the trial. The remaining animals were assigned to 4 groups, each having 6 B and 6 S, raised on pasture with unlimited access to ha...
Identifying randomized clinical trials in Spanish-language dermatology journals.
Sanclemente, G; Pardo, H; Sánchez, S; Bonfill, X
2015-06-01
The necessary foundation for good clinical practice lies in knowledge derived from clinical research. Evidence from randomized clinical trials (RCTs) is the pillar on which decisions about therapy are based. To search exhaustively and rigorously to identify RCTs in dermatology journals published in Spanish. We located dermatology journals through the following search engines and indexes: PubMed, LILACS, SciELO, Periódica, Latindex, Índice Médico Español, C-17, IBECS, EMBASE, and IMBIOMED. We also sought information through dermatology associations and dermatologists in countries where Spanish was the usual language of publication, and we searched the Internet (Google). Afterwards we searched the journals electronically and manually to identify RCTs in all available volumes and issues, checking from the year publication started through 2012. Of 28 journals identified, we included 21 in the search. We found a total of 144 RCTs published since 1969; 78 (54%) were in Latin American journals and 66 (46%) were in Spanish journals. The most frequent disease contexts for RCTs in Spanish journals were psoriasis, mycoses, and acne vulgaris. In Latin American journals, the most frequent disease contexts were common warts, mycoses, acne vulgaris, and skin ulcers on the lower limbs. Manual searches identified more RCTs than electronic searches. Manual searches found a larger number of RCTs. Relatively fewer RCTs are published in Spanish and Latin American journals than in English-language journals. Internet facilitated access to full texts published by many journals; however, free open access to these texts is still unavailable and a large number of journal issues are still not posted online. Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved.
NASA Astrophysics Data System (ADS)
Sundin, Per
2010-04-01
We perform a detailed study of the type IIA superstring in {text{Ad}}{{text{S}}_4} × mathbb{C}{mathbb{P}_3} . After introducing suitable bosonic light-cone and fermionic kappa worldsheet gauges we derive the pure boson and fermion SU(2|2)×U(1) covariant light-cone Hamiltonian up to quartic order in fields. As a first application of our derivation we calculate energy shifts for string configurations in a closed fermionic subsector and successfully match these with a set of light-cone Bethe equations. We then turn to investigate the mismatch between the degrees of freedom of scattering states and oscillatory string modes. Since only light string modes appear as fundamental Bethe roots in the scattering theory, the physical role of the remaining 4 F + 4 B massive oscillators is rather unclear. By continuing a line of research initiated by Zarembo, we shed light on this question by calculating quantum corrections for the propagators of the bosonic massive fields. We show that, once loop corrections are incorporated, the massive coordinates dissolve in a continuum state of two light particles.
ERIC Educational Resources Information Center
El Brocense; And Others
1980-01-01
This section consists of reprints on the following topics: (1) the misuse of "en"; (2) anglicisms; (3) widespread use of vulgar language; (4) an interview with Emilio Criado on Spanish language variation; (5) use of the feminine in professional titles; and (6) Spanish, the national language of Latin American countries. (AMH)
Reading difficulties in Spanish adults with dyslexia.
Suárez-Coalla, Paz; Cuetos, Fernando
2015-04-01
Recent studies show that dyslexia persists into adulthood, even in highly educated and well-read people. The main characteristic that adults with dyslexia present is a low speed when reading. In Spanish, a shallow orthographic system, no studies about adults with dyslexia are available; and it is possible that the consistency of the orthographic system favours the reading fluency. The aim of this study was to get an insight of the reading characteristics of Spanish adults with dyslexia and also to infer the reading strategies that they are using. For that purpose, a group of 30 dyslexics (M age = 32 years old) and an age-matched group of 30 adults without reading disabilities completed several phonological and reading tasks: phonological awareness tasks, rapid automatic naming, lexical decision, word and pseudoword reading, letter detection and text reading. The results showed that highly educated Spanish dyslexics performed significantly worse than the control group in the majority of the tasks. Specifically, they showed difficulties reading long pseudowords, indicating problems in automating the grapheme-phoneme rules, but they also seem to present difficulties reading words, which indicate problems with the lexical route. It seems that the Spanish dyslexic adults, as in deep orthographies, continue having difficulties in phonological awareness tasks, rapid naming and reading.
Wallace Bihm, Jasmine; Szekely, Daniel; Nielsen, Peter; Murray, Elizabeth; Abroms, Lorien; Snider, Jeremy
2014-01-01
previous baby, and race/ethnicity, there was a significant effect of Text4baby intervention exposure on increased agreement with belief in the importance of taking prenatal vitamins (OR 1.91, 95% CI 1.08-3.34, P=.024). All of these attitudes had been targeted by at least one text message during the 4-week evaluation period examined in this study. In unadjusted models, there was a significant effect of intervention exposure on belief in the importance of visiting a health care provider to be a healthy new mother (OR 1.52, 95% CI 1.01-2.31, P=.046) and in the health risks of alcohol during pregnancy (OR 2.06, 95% CI 1.00-4.31, P=.05). No behavioral effects of the intervention were observed in this analysis. Conclusions Text4baby is a promising program that offers lessons for future mHealth activities. This large-scale study demonstrated initial effects of the program on attitudes and beliefs targeted by the messages received by women during the study period. Results confirm previous findings from Text4baby studies and other mHealth research. Future analyses will examine dosage effects of the intervention on behaviors and clinical outcomes. PMID:24846909
Computation of eigenpairs of Ax = lambda Bx for vibrations of spinning deformable bodies
NASA Technical Reports Server (NTRS)
Utku, S.; Clemente, J. L. M.
1984-01-01
It is shown that, when linear theory is used, the general eigenvalue problem related with the free vibrations of spinning deformable bodies is of the type AX = lambda Bx, where A is Hermitian, and B is real positive definite. Since the order n of the matrices may be large, and A and B are banded or block banded, due to the economics of the numerical solution, one is interested in obtaining only those eigenvalues which fall within the frequency band of interest of the problem. The paper extends the well known method of bisections and iteration of R to the n power to n dimensional complex spaces, i.e., to C to the n power, so that it can be applied to the present problem.
Spanish as a Second Language when L1 Is Quechua: Endangered Languages and the SLA Researcher
ERIC Educational Resources Information Center
Kalt, Susan E.
2012-01-01
Spanish is one of the most widely spoken languages in the world. Quechua is the largest indigenous language family to constitute the first language (L1) of second language (L2) Spanish speakers. Despite sheer number of speakers and typologically interesting contrasts, Quechua-Spanish second language acquisition is a nearly untapped research area,…
Goncharov, Alexey I; Maslakova, Aitsana A; Polikarpova, Anna V; Bulanova, Elena A; Guseva, Alexandra A; Morozov, Ivan A; Rubtsov, Petr M; Smirnova, Olga V; Shchelkunova, Tatiana A
2017-01-01
Recent studies suggest that progesterone may possess anti-tumorigenic properties. However, a growth-modulatory role of progestins in human cancer cells remains obscure. With the discovery of a new class of membrane progesterone receptors (mPRs) belonging to the progestin and adipoQ receptor gene family, it becomes important to study the effect of this hormone on proliferation of tumor cells that do not express classical nuclear progesterone receptors (nPRs). To identify a cell line expressing high levels of mPRs and lacking nPRs, we examined mRNA levels of nPRs and three forms of mPRs in sixteen human tumor cell lines of different origin. High expression of mPR mRNA has been found in pancreatic adenocarcinoma BxPC3 cells, while nPR mRNA has not been detected in these cells. Western blot analysis confirmed these findings at the protein level. We revealed specific binding of labeled progesterone in these cells with affinity constant similar to that of human mPR expressed in yeast cells. Progesterone at high concentration of 20 μM significantly reduced the mRNA levels of proliferation markers Ki67 and PCNA, as well as of cyclin D1, and increased the mRNA levels of cyclin dependent kinase inhibitors p21 and p27. Progesterone (1 μM and 20 μM) significantly inhibited proliferative activity of BxPC3 cells. These results point to anti-proliferative effects of the progesterone high concentrations on BxPC3 cells and suggest that activation of mPRs may mediate this action. Our data are a starting point for further investigations regarding the application of progesterone in pancreatic cancer. Copyright © 2016 Elsevier Ltd. All rights reserved.
Salta a Cantar (Jump Up to Sing). Children's Songs in Spanish.
ERIC Educational Resources Information Center
Warner, Mona
Since most children like to sing, singing Spanish songs is a learning experience that will be remembered. For Spanish speaking children, singing Spanish songs will build their self esteem and create a more comfortable environment. Children who do not speak Spanish will obtain a good feeling for the beauty of the language and will enjoy learning…
ERIC Educational Resources Information Center
Hidalgo, Margarita
1987-01-01
Discusses the rise of Mexican Spanish as a distinct variety of Spanish and describes the regional and social dialects of contemporary Mexican Spanish. Although countless similarities exist between Mexican Spanish and the Chicano Spanish spoken in the southwestern United States, Mexican Spanish shows greater variability. (GR)
Stoltz, D; Stoltz, S E; Johansson, L S O
2007-07-04
We present a systematic study of different reconstructions obtained after deposition of Au on the [Formula: see text]-4H-SiC(0001) surface. For 1-2 monolayers (ML) Au and annealing temperature T(anneal)∼675 °C, a 3 × 3 reconstruction was observed. For 4 ML Au and T(anneal)∼650 °C, a [Formula: see text] reconstruction appeared, while 5 ML Au annealed at 700 °C reconstructed to give a [Formula: see text] pattern. From the Si 2p and Au 4f core-level components, we propose interface models, depending on the amount of Au on the surface and the annealing temperature. For 1-4 ML Au annealed at 650-675 °C, gold diffuses under the topmost Si into the SiC and forms a silicide. An additional Si component in our Si 2p spectra is related to the interface between the silicide and SiC. For 5 ML Au annealed at 700 °C, silicide is also formed at the surface, covering unreacted Au on top of the SiC substrate. The interface Si component is also observed in the Si 2p spectra of this surface. The key role in [Formula: see text]-4H-SiC(0001) interface formation is played by diffusion and the silicon-richness of the surface.
21 CFR 201.16 - Drugs; Spanish-language version of certain required statements.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Drugs; Spanish-language version of certain...; Spanish-language version of certain required statements. An increasing number of medications restricted to prescription use only are being labeled solely in Spanish for distribution in the Commonwealth of Puerto Rico...
21 CFR 201.16 - Drugs; Spanish-language version of certain required statements.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Drugs; Spanish-language version of certain...; Spanish-language version of certain required statements. An increasing number of medications restricted to... where Spanish is the predominant language. Such labeling is authorized under § 201.15(c). One required...
Cuesta-Barriuso, Rubén; Torres-Ortuño, Ana; Galindo-Piñana, Pilar; Nieto-Munuera, Joaquín; Duncan, Natalie; López-Pina, José Antonio
2017-01-01
We aimed to conduct a validation in Spanish of the Validated Hemophilia Regimen Treatment Adherence Scale - Prophylaxis (VERITAS-Pro) questionnaire for use in patients with hemophilia under prophylactic treatment. The VERITAS-Pro scale was adapted through a process of back translation from English to Spanish. A bilingual native Spanish translator translated the scale from English to Spanish. Subsequently, a bilingual native English translator translated the scale from Spanish to English. The disagreements were resolved by agreement between the research team and translators. Seventy-three patients with hemophilia, aged 13-62 years, were enrolled in the study. The scale was applied twice (2 months apart) to evaluate the test-retest reliability. Internal consistency reliability was lower on the Spanish VERITAS-Pro than on the English version. Test-retest reliability was high, ranging from 0.83 to 0.92. No significant differences ( P >0.05) were found between test and retest scores in subscales of VERITAS-Pro. In general, Spanish patients showed higher rates of nonadherence than American patients in all subscales. The Spanish version of the VERITAS-Pro has high levels of consistency and empirical validity. This scale can be administered to assess the degree of adherence of prophylactic treatment in patients with hemophilia.
Translation and validation of a Spanish version of the xerostomia inventory.
Serrano, Carlos; Fariña, María P; Pérez, Cristhian; Fernández, Marcos; Forman, Katherine; Carrasco, Mauricio
2016-12-01
The aim of this study was to validate a Spanish cross-cultural adaptation of the xerostomia inventory (XI). The original English version of XI was translated into Spanish, cross-culturally adapted and field tested. The Spanish version of XI (XI-Sp) was tested with a sample of 41 patients with xerostomia. The reliability of the XI-Sp was determined through internal consistency and test-retest methods. The construct validity of XI-Sp was determined by means of correlation between XI-Sp scores and salivary flow measurements. Overall XI-Sp scores were 40.8 (SD = 10) for the first application and 40.2 (SD = 9.5) for the second. Cronbach's alpha value for the XI-Sp was 0.89 and 0.87, respectively, while interitem correlation averages were r = 0.44 and r = 0.39 for each application. Interitem correlation and corrected total was r c ≥0.30. The test-retest intraclass correlation coefficient value for the XI-Sp score was 0.59 and 0.91. Convergent validity for construct validity correlation with salivary flow showed a medium effect size (r 2 = 0.10) for the first application but did not make a statistically significant prediction for the second (r 2 = 0.7). This study provides evidence concerning the reliability of the XI-Sp, showing that it may be a useful tool for Spanish-speaking xerostomia patients for both clinical and epidemiologic research. © 2015 John Wiley & Sons A/S and The Gerodontology Association. Published by John Wiley & Sons Ltd.
The contribution of GPR98 and DFNB31 genes to a Spanish Usher syndrome type 2 cohort.
García-García, Gema; Besnard, Thomas; Baux, David; Vaché, Christel; Aller, Elena; Malcolm, Sue; Claustres, Mireille; Millan, Jose M; Roux, Anne-Françoise
2013-01-01
Usher syndrome type 2 (USH2) is an autosomal recessive disease characterized by moderate to severe hearing loss and retinitis pigmentosa. To date, three disease-causing genes have been identified, USH2A, GPR98, and DFNB31, of which USH2A is clearly the major contributor. The aim of this work was to determine the contribution of GPR98 and DFNB31 genes in a Spanish cohort of USH2A negative patients using exhaustive molecular analysis, including sequencing, dosage, and splicing analysis. Linkage analysis was performed to prioritize the gene to study, followed by sequencing of exons and intron-exon boundaries of the selected gene, GPR98 (90 exons) or DFNB31 (12 exons). Functional splicing analyses and comparative genomic hybridization array to detect large rearrangements were performed when appropriate. We confirmed that mutations in GPR98 contribute a significant but minor role to Usher syndrome type 2. In a group of patients referred for molecular diagnosis, 43 had been found to be positive for USH2A mutations, the remaining 19 without USH2A alterations were screened, and seven different mutations were identified in the GPR98 gene in seven patients (five in the homozygous state), of which six were novel. All detected mutations result in a truncated protein; deleterious missense mutations were not found. No pathological mutations were identified in the DFNB31 gene. In Spain, USH2A and GPR98 are responsible for 95.8% and 5.2% of USH2 mutated cases, respectively. DFNB31 plays a minor role in the Spanish population. There was a group of patients in whom no mutation was found. These findings confirm the importance of including at least GPR98 analysis for comprehensive USH2 molecular diagnosis.
The contribution of GPR98 and DFNB31 genes to a Spanish Usher syndrome type 2 cohort
García-García, Gema; Besnard, Thomas; Baux, David; Vaché, Christel; Aller, Elena; Malcolm, Sue; Claustres, Mireille; Millan, Jose M.
2013-01-01
Background Usher syndrome type 2 (USH2) is an autosomal recessive disease characterized by moderate to severe hearing loss and retinitis pigmentosa. To date, three disease-causing genes have been identified, USH2A, GPR98, and DFNB31, of which USH2A is clearly the major contributor. The aim of this work was to determine the contribution of GPR98 and DFNB31 genes in a Spanish cohort of USH2A negative patients using exhaustive molecular analysis, including sequencing, dosage, and splicing analysis. Methods Linkage analysis was performed to prioritize the gene to study, followed by sequencing of exons and intron-exon boundaries of the selected gene, GPR98 (90 exons) or DFNB31 (12 exons). Functional splicing analyses and comparative genomic hybridization array to detect large rearrangements were performed when appropriate. Results We confirmed that mutations in GPR98 contribute a significant but minor role to Usher syndrome type 2. In a group of patients referred for molecular diagnosis, 43 had been found to be positive for USH2A mutations, the remaining 19 without USH2A alterations were screened, and seven different mutations were identified in the GPR98 gene in seven patients (five in the homozygous state), of which six were novel. All detected mutations result in a truncated protein; deleterious missense mutations were not found. No pathological mutations were identified in the DFNB31 gene. Conclusions In Spain, USH2A and GPR98 are responsible for 95.8% and 5.2% of USH2 mutated cases, respectively. DFNB31 plays a minor role in the Spanish population. There was a group of patients in whom no mutation was found. These findings confirm the importance of including at least GPR98 analysis for comprehensive USH2 molecular diagnosis. PMID:23441107
ERIC Educational Resources Information Center
Ortiz, Arlene; Clinton, Amanda; Schaefer, Barbara A.
2015-01-01
Convergent and discriminant validity evidence was examined for scores on the Spanish Record Form of the Bracken School Readiness Assessment, Third Edition (BSRA-3). Participants included a sample of 68 Hispanic, Spanish-speaking children ages 4 to 5 years enrolled in preschool programs in Puerto Rico. Scores obtained from the BSRA-3 Spanish Record…
Bibliography of Spanish Materials for Children: Kindergarten Through Grade Six.
ERIC Educational Resources Information Center
Gonsalves, Julia, Comp.; And Others
This annotated bibliography of instructional materials, intended for students, teachers, and native speakers of Spanish, contains more than 400 items emphasizing both language and culture. The entries are arranged alphabetically in sections including: (1) books in series; (2) children's literature; (3) dictionaries and encyclopedias; (4)…
Chen, Peng; Shi, Shengbin; Wang, Hang; Qiu, Fanglong; Wang, Yuxi; Tang, Yumin; Feng, Jian-Rui; Guo, Han; Cheng, Xing; Guo, Xugang
2018-06-27
High-performance polymer solar cells (PSCs) with thick active layers are essential for large-scale production. Polymer semiconductors exhibiting a temperature-dependent aggregation property offer great advantages toward this purpose. In this study, three difluorobenzoxadiazole (ffBX)-based donor polymers, PffBX-T, PffBX-TT, and PffBX-DTT, were synthesized, which contain thiophene (T), thieno[3,2- b]thiophene (TT), and dithieno[3,2- b:2',3'- d]thiophene (DTT) as the π-spacers, respectively. Temperature-dependent absorption spectra reveal that the aggregation strength increases in the order of PffBX-T, PffBX-TT, and PffBX-DTT as the π-spacer becomes larger. PffBX-TT with the intermediate aggregation strength enables well-controlled disorder-order transition in the casting process of blend film, thus leading to the best film morphology and the highest performance in PSCs. Thick-film PSCs with an average power conversion efficiency (PCE) of 8.91% and the maximum value of 9.10% are achieved using PffBX-TT:PC 71 BM active layer with a thickness of 250 nm. The neat film of PffBX-TT also shows a high hole mobility of 1.09 cm 2 V -1 s -1 in organic thin-film transistors. When PffBX-DTT and PffBX-T are incorporated into PSCs utilizing PC 71 BM acceptor, the average PCE decreases to 6.54 and 1.33%, respectively. The performance drop mainly comes from reduced short-circuit current, as a result of nonoptimal blend film morphology caused by a less well-controlled film formation process. A similar trend was also observed in nonfullerene type thick-film PSCs using IT-4F as the electron acceptor. These results show the significance of polymer aggregation strength tuning toward optimal bulk heterojunction film morphology using ffBX-based polymer model system. The study demonstrates that adjusting π-spacer is an effective method, in combination with other important approaches such as alkyl chain optimization, to generate high-performance thick-film PSCs which are critical for
ERIC Educational Resources Information Center
Arce, Eugene; And Others
A curriculum guide for secondary levels 1 and 2 offers a linguistic and cultural program for native speakers of Spanish. Designed especially for bilingual students in Texas, the guide recognizes the high level of linguistic achievement of the Spanish-speaking pupils, and stresses an appreciation of Hispanic culture. The bulletin provides…
ERIC Educational Resources Information Center
Cruz, Sylvia; And Others
In a study designed to assess effects of administering the Metropolitan Reading Test (MRT) in Spanish versus English, 100 Puerto Rican kindergarten pupils were randomly split into two groups. The MRT was administered in English to one group and in a Spanish translation to the other group. The group who took the Spanish version significantly…
Pregnancy in Spanish elite sportswomen: A qualitative study.
Martínez-Pascual, Beatriz; Alvarez-Harris, Sara; Fernández-de-Las-Peñas, César; Palacios-Ceña, Domingo
2017-07-01
Pregnancy and motherhood have been historically considered as reasons why elite sportswomen may end their sport careers. During pregnancy, the safety of both mother and baby has been identified as a key reason for ceasing sport participation. Recent "official" statistics on how many elite athletes are mothers suggest that pregnancy, motherhood, and sport could be no longer mutually exclusive. The aim of this qualitative phenomenological study was to describe the lived pregnancy of Spanish elite sportswomen. Spanish elite sportswomen (n = 20) aged between 18 and 65 years that had been pregnant during their sporting professional career and after the end of their pregnancy had taken up again their professional sporting career for at least one year were included. Data were collected from May 2010 to April 2012 using in-depth personal interviews, investigator's field notes, and extracts from the participants' personal letters. Identified themes included: (1) choosing the right moment; (2) fears and doubts; and (3) justifying physical exercise. By giving voice to these elite Spanish sportswomen, their pregnancy experiences are made visible, which might help to gain a better understanding into their expectations and develop policies and practices focused on elite sportswomen during and after pregnancy.
Ricci, Davide; Tazelaar, Henry D; Miyagi, Naoto; Rao, Vinay P; Pedersen, Rachel A; Kremers, Walter K; Byrne, Guerard W; McGregor, Christopher G A
2007-01-01
Introduction Endomyocardial biopsy (EmBx) is the standard means of establishing cardiac allograft rejection diagnosis. The efficacy of this procedure in xenotransplantation has not been determined. In this study we compare the histology of right ventricular EmBx specimens with the corresponding full cross sections of explanted right ventricle (RV). We also compare RV with the related left ventricle (LV) cross sections. Methods Heterotopic CD46 pig to baboon cardiac xenotransplants (n=64) were studied. RVEmBxs were taken at cardiac explant, using either a standard bioptome (RVEmBxBT; n=24) or by sharp dissection (RVEmBxSD; n=40). Hematoxylin-eosin stained sections of RV and LV cross section and RVEmBxs were compared in a blinded fashion. Characteristics of delayed xenograft rejection (DXR) and a global assessment of ischemia, were scored from 0 to 4 based on the percentage of myocardium involved (0 = 0%, 1=1−25%, 2 = 26−50%, 3 = 51−75%, 4 = 76−100%). Results Median graft survival was 30 days (range 3–137). Linear regression analysis of histology scores demonstrated that both RVEmBxBT and RVEmBxSD equally represented the histology of RV cross section. Global ischemic injury was strongly correlated between RV and RVEmBx (R2=0.84) and between RV and LV cross sections (R2=0.84). Individual characteristics of DXR showed no significant variation between RV and RVEmBx or between RV and LV (p<0.05). Conclusions These results indicate that DXR is a widespread process involving both right and left ventricles similarly. This study shows that histologic assessment of RVEmBx specimens is an effective method for the monitoring of DXR after cardiac xenotransplantation. PMID:17919623
Development of a Brief Questionnaire of Smoking Urges--Spanish
ERIC Educational Resources Information Center
Cepeda-Benito, Antonio; Reig-Ferrer, Abilio
2004-01-01
Using 2 different samples of smokers, the authors developed and cross-validated a Spanish, brief version of the Questionnaire of Smoking Urges (QSU; S. T. Tiffany & D. J. Drobes, 1991). The smokers in Study 1 (N = 245) and Study 2 (N = 225) were from the province of Alicante, Spain. In both samples, a 2-factor model provided an excellent fit for a…
[Induced abortions among Spanish women in England and Wales (1974-1988)].
Peiró, R; Colomer, C; Ashton, J; Alvarez-Dardet, C
1994-01-01
To assess the importance of travelling for abortion in Spanish women from 1974 to 1988, a descriptive epidemiologic study was undertaken, based on information from the United Kingdom Office for Population Censuses and Surveys. Additionally, the effect of the democratic restitution in Spain (1978) and of the passing of the Spanish abortion law in Spain is explored. During the study period, close to 200,000 Spanish women travelled to England and Wales to have an abortion. The annual figures range from 2,978 in 1974 to 22,002 in 1983. In 1988, in spite of the partial decriminalization of abortion in Spain, still 3,188 travelled to the UK for an abortion. In average, 1 out 35 Spanish women in fertile ages travelled to England and Wales for this reason in the study period. The likelihood was higher for the cohort of women born between 1955 and 1959, for which the risk was 4.5%. The proportional distribution by age shows that teenagers increased their relative importance from 9.3% in 1974 to 17% in 1988, suggesting less benefits for this age group than for older women from the democratization of the country and the abortion law.
The Challenges of Spanish Language Teaching in Multilingual India: A Case Study of Delhi
ERIC Educational Resources Information Center
Rai, Dhiraj Kumar
2017-01-01
The multilingual surrounding of Spanish Language Teaching (SLT) in India has presented a unique linguistic principle. This principle relies upon the application of English language instructions (as FL1) to combine several methods for teaching-learning Spanish language (as FL2). However, the effectiveness and appropriateness of this linguistic…
ERIC Educational Resources Information Center
Ramirez, Arnulfo G.; Politzer, Robert L.
A revised Spanish/English oral-proficiency test battery was administered to 40 Spanish-surnamed pupils equally divided by sex at grade levels 1, 3, 5, and 7. The test battery included parallel Spanish and English versions of: (1) a 12-item vocabulary pretest, (2) a 32-item vocabulary-by-domain test consisting of four sections--home, neighborhood,…
ERIC Educational Resources Information Center
Bell, Mozelle Sawyer; Arribas, E. Jaime
This Spanish ecology packet contains resource units and materials for intermediate and advanced Spanish classes. It is designed to be used for individual and small-group instruction in the senior high school to supplement the Spanish language curriculum. Included are articles, pictures, and cartoons from Spanish-language newspapers and magazines…
Valdois, Sylviane; Peyrin, Carole; Lassus-Sangosse, Delphine; Lallier, Marie; Démonet, Jean-François; Kandel, Sonia
2014-04-01
We report the case study of a French-Spanish bilingual dyslexic girl, MP, who exhibited a severe visual attention (VA) span deficit but preserved phonological skills. Behavioural investigation showed a severe reduction of reading speed for both single items (words and pseudo-words) and texts in the two languages. However, performance was more affected in French than in Spanish. MP was administered an intensive VA span intervention programme. Pre-post intervention comparison revealed a positive effect of intervention on her VA span abilities. The intervention further transferred to reading. It primarily resulted in faster identification of the regular and irregular words in French. The effect of intervention was rather modest in Spanish that only showed a tendency for faster word reading. Text reading improved in the two languages with a stronger effect in French but pseudo-word reading did not improve in either French or Spanish. The overall results suggest that VA span intervention may primarily enhance the fast global reading procedure, with stronger effects in French than in Spanish. MP underwent two fMRI sessions to explore her brain activations before and after VA span training. Prior to the intervention, fMRI assessment showed that the striate and extrastriate visual cortices alone were activated but none of the regions typically involved in VA span. Post-training fMRI revealed increased activation of the superior and inferior parietal cortices. Comparison of pre- and post-training activations revealed significant activation increase of the superior parietal lobes (BA 7) bilaterally. Thus, we show that a specific VA span intervention not only modulates reading performance but further results in increased brain activity within the superior parietal lobes known to housing VA span abilities. Furthermore, positive effects of VA span intervention on reading suggest that the ability to process multiple visual elements simultaneously is one cause of successful
Item analysis of three Spanish naming tests: a cross-cultural investigation.
Marquez de la Plata, Carlos; Arango-Lasprilla, Juan Carlos; Alegret, Montse; Moreno, Alexander; Tárraga, Luis; Lara, Mar; Hewlitt, Margaret; Hynan, Linda; Cullum, C Munro
2009-01-01
Neuropsychological evaluations conducted in the United States and abroad commonly include the use of tests translated from English to Spanish. The use of translated naming tests for evaluating predominately Spanish-speakers has recently been challenged on the grounds that translating test items may compromise a test's construct validity. The Texas Spanish Naming Test (TNT) has been developed in Spanish specifically for use with Spanish-speakers; however, it is unlikely patients from diverse Spanish-speaking geographical regions will perform uniformly on a naming test. The present study evaluated and compared the internal consistency and patterns of item-difficulty and -discrimination for the TNT and two commonly used translated naming tests in three countries (i.e., United States, Colombia, Spain). Two hundred fifty two subjects (136 demented, 116 nondemented) across three countries were administered the TNT, Modified Boston Naming Test-Spanish, and the naming subtest from the CERAD. The TNT demonstrated superior internal consistency to its counterparts, a superior item difficulty pattern than the CERAD naming test, and a superior item discrimination pattern than the MBNT-S across countries. Overall, all three Spanish naming tests differentiated nondemented and moderately demented individuals, but the results suggest the items of the TNT are most appropriate to use with Spanish-speakers. Preliminary normative data for the three tests examined in each country are provided.
ITEM ANALYSIS OF THREE SPANISH NAMING TESTS: A CROSS-CULTURAL INVESTIGATION
de la Plata, Carlos Marquez; Arango-Lasprilla, Juan Carlos; Alegret, Montse; Moreno, Alexander; Tárraga, Luis; Lara, Mar; Hewlitt, Margaret; Hynan, Linda; Cullum, C. Munro
2009-01-01
Neuropsychological evaluations conducted in the United States and abroad commonly include the use of tests translated from English to Spanish. The use of translated naming tests for evaluating predominately Spanish-speakers has recently been challenged on the grounds that translating test items may compromise a test’s construct validity. The Texas Spanish Naming Test (TNT) has been developed in Spanish specifically for use with Spanish-speakers; however, it is unlikely patients from diverse Spanish-speaking geographical regions will perform uniformly on a naming test. The present study evaluated and compared the internal consistency and patterns of item-difficulty and -discrimination for the TNT and two commonly used translated naming tests in three countries (i.e., United States, Colombia, Spain). Two hundred fifty two subjects (126 demented, 116 nondemented) across three countries were administered the TNT, Modified Boston Naming Test-Spanish, and the naming subtest from the CERAD. The TNT demonstrated superior internal consistency to its counterparts, a superior item difficulty pattern than the CERAD naming test, and a superior item discrimination pattern than the MBNT-S across countries. Overall, all three Spanish naming tests differentiated nondemented and moderately demented individuals, but the results suggest the items of the TNT are most appropriate to use with Spanish-speakers. Preliminary normative data for the three tests examined in each country are provided. PMID:19208960
Guiberson, Mark; Rodríguez, Barbara L; Dale, Philip S
2011-10-01
The purpose of the current study was to examine the concurrent validity and classification accuracy of 3 parent report measures of language development in Spanish-speaking toddlers. Forty-five Spanish-speaking parents and their 2-year-old children participated. Twenty-three children had expressive language delays (ELDs) as determined through multiple sources of information, and 22 had typical language development (TD). Parents completed the Spanish version of the Ages and Stages Questionnaire (Spanish ASQ; Squires, Potter, & Bricker, 1999) and the short-form of the Inventarios del Desarrollo de Habilidades Comunicativas Palabras y Enunciados (INV-II; Jackson-Maldonado, Bates, & Thal, 1992; Jackson-Maldonado et al., 2003), which is the Spanish version of the MacArthur-Bates Communicative Development Inventories Words and Sentences form, and reported children's 3 longest utterances (M3L-W). Children were administered the Preschool Language Scale, Fourth Edition, Spanish Edition (SPLS-4; Zimmerman, Steiner, & Pond, 2002) at early childhood centers. All 3 parent report measures were significantly correlated with the SPLS-4, establishing their concurrent validity. Children with ELDs scored significantly lower than TD children on all 3 parent report measures. The Spanish ASQ demonstrated less than desirable levels of sensitivity and specificity; both the short-form INV-II and M3L-W measures demonstrated favorable sensitivity and specificity. Of these measures, M3L-W demonstrated the strongest classification accuracy qualities, including sensitivity, negative predictive value, and area under the receiver operating characteristics curve. The short-form INV-II and M3L-W demonstrated highly satisfactory classification accuracy of ELDs, but M3L-W demonstrated slightly stronger accuracy. These results indicate that these measures may be useful in screening for ELDs in Spanish-speaking toddlers.
Borque-Fernando, Á; Esteban-Escaño, L M; Rubio-Briones, J; Lou-Mercadé, A C; García-Ruiz, R; Tejero-Sánchez, A; Muñoz-Rivero, M V; Cabañuz-Plo, T; Alfaro-Torres, J; Marquina-Ibáñez, I M; Hakim-Alonso, S; Mejía-Urbáez, E; Gil-Fabra, J; Gil-Martínez, P; Ávarez-Alegret, R; Sanz, G; Gil-Sanz, M J
2016-04-01
To prevent the overdiagnosis and overtreatment of prostate cancer (PC), therapeutic strategies have been established such as active surveillance and focal therapy, as well as methods for clarifying the diagnosis of high-grade prostate cancer (HGPC) (defined as a Gleason score ≥7), such as multiparametric magnetic resonance imaging and new markers such as the 4Kscore test (4KsT). By means of a pilot study, we aim to test the ability of the 4KsT to identify HGPC in prostate biopsies (Bx) and compare the test with other multivariate prognostic models such as the Prostate Cancer Prevention Trial Risk Calculator 2.0 (PCPTRC 2.0) and the European Research Screening Prostate Cancer Risk Calculator 4 (ERSPC-RC 4). Fifty-one patients underwent a prostate Bx according to standard clinical practice, with a minimum of 10 cores. The diagnosis of HGPC was agreed upon by 4 uropathologists. We compared the predictions from the various models by using the Mann-Whitney U test, area under the ROC curve (AUC) (DeLong test), probability density function (PDF), box plots and clinical utility curves. Forty-three percent of the patients had PC, and 23.5% had HGPC. The medians of probability for the 4KsT, PCPTRC 2.0 and ERSPC-RC 4 were significantly different between the patients with HGPC and those without HGPC (p≤.022) and were more differentiated in the case of 4KsT (51.5% for HGPC [25-75 percentile: 25-80.5%] vs. 16% [P 25-75: 8-26.5%] for non-HGPC; p=.002). All models presented AUCs above 0.7, with no significant differences between any of them and 4KsT (p≥.20). The PDF and box plots showed good discriminative ability, especially in the ERSPC-RC 4 and 4KsT models. The utility curves showed how a cutoff of 9% for 4KsT identified all cases of HGPC and provided a 22% savings in biopsies, which is similar to what occurs with the ERSPC-RC 4 models and a cutoff of 3%. The assessed predictive models offer good discriminative ability for HGPCs in Bx. The 4KsT is a good classification
Baldwin, Carol M.; Choi, Myunghan; McClain, Darya Bonds; Celaya, Alma; Quan, Stuart F.
2012-01-01
; Choi M; McClain DB; Celaya A; Quan SF. Spanish translation and cross-language validation of a Sleep Habits Questionnaire for use in clinical and research settings. J Clin Sleep Med 2012;8(2):137-146. PMID:22505858
Fernández-Guerrero, Inés María; Martín-Sánchez, Francisco Javier; Burillo-Putze, Guillermo; Miró, Òscar
2017-10-01
To analyze the research output of Spanish emergency physicians between 2005 and 2014 and to compare it to their output in the previous 10-year period (1995-2004) as well as to that of emergency physicians in other countries and Spanish physicians in other specialties. Original articles indexed in the Science Citation Index Expanded of the Web of Science were included. Documents from Spanish emergency physicians were identified by combining the word Spain and any other search term identifying an emergency service or unit in Spain. To identify articles from 7 other Spanish specialties (hematology, endocrinology, cardiology, pneumology, digestive medicine, pediatrics, surgery and orthopedic medicine or traumatology) and emergency physicians in 8 other countries (United States, United Kingdom, Ireland, Italy, France, Germany, Netherlands, Belgium) we used similar strategies. Information about production between 1995 and 2004 was extracted from a prior publication. Spanish emergency physicians signed 1254 articles (mean [SD], 125 [44] articles/y) between 2005 and 2014. That level of productivity was greater than in the 1995-2004 period (mean, 26 [14] articles/y), although the annual growth rate fell from 12.5% in the previous 10-year period to 5.2% in the most recent one. Emergency medicine was among the least productive Spanish specialties we studied, but our discipline's annual growth rate of 5.2% was the highest. Spanish emergency medicine occupies an intermediate position (ranking fifth) among the 9 countries studied, although the population-adjusted rank was higher (fourth). When output was adjusted for gross domestic product, Spain climbed higher in rank, to second position. The annual growth rate was the fourth highest among countries, after Germany (9.9%), the Netherlands (7.3%), and Italy (6.0%). The research output of Spanish emergency physicians continues to be quantitatively lower than that of other Spanish specialties and of emergency physicians in other
High School Spanish Teachers' Attitudes and Practices toward Spanish Heritage Language Learners
ERIC Educational Resources Information Center
Russell, Brittany D.; Kuriscak, Lisa M.
2015-01-01
This case study uses survey data to examine the attitudes and pedagogical practices of preservice and current high school Spanish teachers toward Spanish heritage language learners (HLLs). The research questions addressed were (1) the extent to which participants were aware of the challenges facing Spanish HLLs who are enrolled in traditional…
Spanish-Language Learners and Latinos: Two Community-Based Projects
ERIC Educational Resources Information Center
López, Sylvia
2014-01-01
The growing U.S. Latino dispersal is allowing for more interactions between students of Spanish and native Spanish speakers. By working with Latino community members, Spanish instructors help meet the standards for foreign language education developed by the American Council on the Teaching of Foreign Languages. This article describes 2 projects.…
Selecting Spanish Books in the Elementary School
ERIC Educational Resources Information Center
Corona, Elia
2007-01-01
In this article, the author recommends a certain criteria for selecting Spanish-language books for elementary students such as cultural factors, setting, time, age, language and visuals. She also enumerates some authors and a listing of their many bilingual texts, which can be used to enrich a school or classroom library.
Food marketing to children on U.S. Spanish-language television.
Kunkel, Dale; Mastro, Dana; Ortiz, Michelle; McKinley, Christopher
2013-01-01
Latino children in particular are at risk of childhood obesity. Because exposure to televised food marketing is a contributor to childhood obesity, it is important to examine the nutritional quality of foods advertised on Spanish-language children's programming. The authors analyzed a sample of 158 Spanish-language children's television programs for its advertising content and compared them with an equivalent sample of English-language advertising. The authors evaluated nutritional quality of each advertised product using a food rating system from the U.S. Department of Health and Human Services. In addition, the authors assessed compliance with industry self-regulatory pledges. The authors found that amount of food advertising on Spanish-language channels (M = 2.2 ads/hour) was lower than on English-language programs, but the nutritional quality of food products on Spanish-language channels was substantially poorer than on English channels. Industry self-regulation was less effective on Spanish-language channels. The study provides clear evidence of significant disparities. Food advertising targeted at Spanish-speaking children is more likely to promote nutritionally poor food products than advertising on English-language channels. Industry self-regulation is less effective on Spanish-language television channels. Given the disproportionately high rate of childhood obesity among Latinos, the study's findings hold important implications for public health policy.
A sharp lower bound for the sum of a sine series with convex coefficients
NASA Astrophysics Data System (ADS)
Solodov, A. P.
2016-12-01
The sum of a sine series g(\\mathbf b,x)=\\sumk=1^∞ b_k\\sin kx with coefficients forming a convex sequence \\mathbf b is known to be positive on the interval (0,π). Its values near zero are conventionally evaluated using the Salem function v(\\mathbf b,x)=x\\sumk=1m(x) kb_k, m(x)=[π/x]. In this paper it is proved that 2π-2v(\\mathbf b,x) is not a minorant for g(\\mathbf b,x). The modified Salem function v_0(\\mathbf b,x)=x\\bigl(\\sumk=1m(x)-1 kb_k+(1/2)m(x)bm(x)\\bigr) is shown to satisfy the lower bound g(\\mathbf b,x)>2π-2v_0(\\mathbf b,x) in some right neighbourhood of zero. This estimate is shown to be sharp on the class of convex sequences \\mathbf b. Moreover, the upper bound for g(\\mathbf b,x) is refined on the class of monotone sequences \\mathbf b. Bibliography: 11 titles.
TECPR2 Associated Neuroaxonal Dystrophy in Spanish Water Dogs
Jagannathan, Vidhya; Wohlsein, Peter; Baumgärtner, Wolfgang; Seehusen, Frauke; Spitzbarth, Ingo; Grandon, Rodrigo; Drögemüller, Cord; Jäderlund, Karin Hultin
2015-01-01
Clinical, pathological and genetic examination revealed an as yet uncharacterized juvenile-onset neuroaxonal dystrophy (NAD) in Spanish water dogs. Affected dogs presented with various neurological deficits including gait abnormalities and behavioral deficits. Histopathology demonstrated spheroid formation accentuated in the grey matter of the cerebral hemispheres, the cerebellum, the brain stem and in the sensory pathways of the spinal cord. Iron accumulation was absent. Ultrastructurally spheroids contained predominantly closely packed vesicles with a double-layered membrane, which were characterized as autophagosomes using immunohistochemistry. The family history of the four affected dogs suggested an autosomal recessive inheritance. SNP genotyping showed a single genomic region of extended homozygosity of 4.5 Mb in the four cases on CFA 8. Linkage analysis revealed a maximal parametric LOD score of 2.5 at this region. By whole genome re-sequencing of one affected dog, a perfectly associated, single, non-synonymous coding variant in the canine tectonin beta-propeller repeat-containing protein 2 (TECPR2) gene affecting a highly conserved region was detected (c.4009C>T or p.R1337W). This canine NAD form displays etiologic parallels to an inherited TECPR2 associated type of human hereditary spastic paraparesis (HSP). In contrast to the canine NAD, the spinal cord lesions in most types of human HSP involve the sensory and the motor pathways. Furthermore, the canine NAD form reveals similarities to cases of human NAD defined by widespread spheroid formation without iron accumulation in the basal ganglia. Thus TECPR2 should also be considered as candidate gene for human NAD. Immunohistochemistry and the ultrastructural findings further support the assumption, that TECPR2 regulates autophagosome accumulation in the autophagic pathways. Consequently, this report provides the first genetic characterization of juvenile canine NAD, describes the histopathological features
Marginalization of Local Varieties in the L2 Classroom: The Case of U.S. Spanish
ERIC Educational Resources Information Center
Burns, Katharine E.
2018-01-01
The United States is one of the world's most populous Hispanophone countries, with over 35 million Spanish-speakers. In addition, Spanish is the most widely taught foreign language in the United States, with more students enrolled in Spanish at the higher-education level than in all other modern languages combined. How, then, is the United States'…
Mancilla-Martinez, Jeannette; Gámez, Perla B; Vagh, Shaher Banu; Lesaux, Nonie K
2016-01-01
This 2-phase study aims to extend research on parent report measures of children's productive vocabulary by investigating the development (n = 38) of the Spanish Vocabulary Extension and validity (n = 194) of the 100-item Spanish and English MacArthur-Bates Communicative Development Inventories Toddler Short Forms and Upward Extension (Fenson et al., 2000, 2007; Jackson-Maldonado, Marchman, & Fernald, 2013) and the Spanish Vocabulary Extension for use with parents from low-income homes and their 24- to 48-month-old Spanish-English bilingual children. Study participants were drawn from Early Head Start and Head Start collaborative programs in the Northeastern United States in which English was the primary language used in the classroom. All families reported Spanish or Spanish-English as their home language(s). The MacArthur Communicative Development Inventories as well as the researcher-designed Spanish Vocabulary Extension were used as measures of children's English and Spanish productive vocabularies. Findings revealed the forms' concurrent and discriminant validity, on the basis of standardized measures of vocabulary, as measures of productive vocabulary for this growing bilingual population. These findings suggest that parent reports, including our researcher-designed form, represent a valid, cost-effective mechanism for vocabulary monitoring purposes in early childhood education settings.
Validation of the Spanish SIRS with monolingual Hispanic outpatients.
Correa, Amor A; Rogers, Richard; Hoersting, Raquel
2010-09-01
Psychologists are faced with formidable challenges in making their assessment methods relevant to growing numbers of Hispanic clients for whom English is not the primary or preferred language. Among other clinical issues, the determination of malingering has profound consequences for clients. In this investigation, we evaluated a Spanish translation of the Structured Interview of Reported Symptoms (SIRS; Rogers, Bagby, & Dickens, 1992) with 80 Spanish-speaking Hispanic American outpatients. Using a between-subjects simulation design, the Spanish SIRS was found to produce reliable results with small standard errors of measurement. Regarding validity, very large effect sizes (mean Cohen's d= 2.00) were observed between feigners and honest responders for the SIRS primary scales. We consider the potential role of the Spanish SIRS with reference to Spanish translations for other assessment instruments.
Belén Ferro-Rey, M; Roca-Cusachs, Alex; Sicras-Mainar, Antoni; Alvarez-Martín, Carlos; de Salas-Cansado, Marina
2011-07-01
To carry out a budget impact analysis (BIA) of olmesartan/amlodipine (20/5, 40/5 and 40/10mg) marketed as a fixed combination (FC) in its approved indication for the National Health System (NHS). We developed a decision tree model in order to estimate usual hypertension treatment algorithm in Spanish clinical practice. The BIA has been developed from the perspective of the NHS for a period of 3 years (years 2010-2012). Spanish hypertensive population ≥ 35 years old. Introduction into the market of a fixed combination (FC) olmesartan/amlodipine in Spain. Expected costs to be assumed by the Spanish NHS (RRP-VAT) for hypertensive population able to be treated with the FC versus currently assumed costs by the NHS with free combination olmesartan and amlodipine. Estimated pharmaceutical costs in hypertensive population treated with olmesartan and amlodipine (2 pills) would be €25.2M (1(st) year), €26.4M (2011), €27.6M (2012), with a total 3-year period of €79.2M. According to patient tree model, the population able to be treated with FC would be 71,283 patients (2010), with a growth rate of 4.8% in the successive years, which supposes an annual cost of €21.2M (2010), €21.8M (2011) and €22.4M (2012), with a total 3-year period of €65.4M. The BIA shows savings of €13.8M in a total 3-year period. The BIA of FC olmesartan/amlodipine could generate net savings of €13.8M for the NHS in the period ranging from years 2010 to 2012. Copyright © 2010 Elsevier España, S.L. All rights reserved.
Abad-García, María Francisca; González-Teruel, Aurora; Solís Sánchez, Gonzalo
2016-12-01
To describe the role of Anales de Pediatría in highlighting Spanish paediatric research, and to identify the journals with which it competes internationally. Spanish paediatric articles, including those from Anales de Pediatría were identified using the Paediatrics category of the Science Citation Index (2010-2014), and their volume and document type was analysed. For original articles and review articles, the year, the citation and journal of publication was studied. The journals were classified as general and specialised. The productivity of general journals was analysed according to their language, JCR quartile, and article access. A total of 2,701 Spanish paediatric papers were identified, accounting for 2.8% of the paediatrics world output. More than two-thirds (68%) of papers were articles that received an average number of 4.97 citations per article. The 965 papers published in Anales de Pediatría accounted for 38.7% of the Spanish paediatric output, and for 1% of the paediatric world publications. A mean of 1.03 citations per article were received for 439 (45.4%) articles and reviews. Of the 106 journals identified, 82 were classified as specialised (1,196 articles) and 24 as general (741 articles). Anales de Pediatría published 60% of the articles in general journals. The rest of articles (309) were published in general journals published in English (82.8%), with a best position in the JCR ranking (83.4%) and mainly by subscription (73.8%). Anales de Pediatría plays an important role in providing international visibility to a large volume of Spanish scientific production in paediatrics. The results presented are a still only a snapshot of this role that could be used in the near future for assessing its evolution and the changes that could be made in order to improve its quality, positioning and competitiveness. Copyright © 2015 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.
ERIC Educational Resources Information Center
Gabriel, Christoph; Kireva, Elena
2014-01-01
A remarkable example of Spanish-Italian contact is the Spanish variety spoken in Buenos Aires (Porteño), which is said to be prosodically "Italianized" due to migration-induced contact. The change in Porteño prosody has been interpreted as a result of transfer from the first language (L1) that occurred when Italian immigrants learned…
Bautista-Gallego, Joaquín; Arroyo-López, Francisco Noé; Romero-Gil, Verónica; Rodríguez-Gómez, Francisco; Garrido-Fernández, Antonio
2015-06-01
Zinc chloride has been used previously as a preservative in directly brined olives with promising results. However, this is the first time that the effects of ZnCl2 addition (0-1 g L(-1) ) on green Spanish-style table olive (cv. Manzanilla) packaging has been studied. The presence of ZnCl2 affected the physico-chemical characteristics of the products; the presence of the Zn led to lower pH values (particularly just after packaging) and titratable and combined acidity values than the control but did not produce clear trends in the colour parameters. No Enterobacteriaceae were found in any of the treatments evaluated. At the highest ZnCl2 concentrations, the lactic acid bacteria were inhibited while, unexpectedly, its presence showed a lower effect than potassium sorbate against the yeast population. Regardless of the use of potassium sorbate or ZnCl2 , the packages had a reduced microbial biodiversity because only Lactobacillus pentosus and Pichia galeiformis were found at the end of the shelf life. With respect to organoleptic characteristics, the presentations containing ZnCl2 were not differentiated from the traditional product. Zinc chloride was less efficient than potassium sorbate as a yeast inhibitor in green Spanish-style olives, showing clear presentation style dependent behaviour for this property. Its presence produced significant changes in chemical parameters but scarcely affected colour or sensory characteristics. © 2014 Society of Chemical Industry.
Differences in the use of health resources by Spanish and immigrant HIV-infected patients.
Velasco, María; Castilla, Virgilio; Guijarro, Carlos; Moreno, Leonor; Barba, Raquel; Losa, Juan E
2012-10-01
HIV-immigrant use of health services and related cost has hardly been analysed. We compared resource utilisation patterns and direct health care costs between Spanish and immigrant HIV-infected patients. All HIV-infected adult patients treated during the years 2003-2005 (372 patients) in this hospital were included. We evaluated the number of out-patient, Emergency Room (ER) and Day-care Unit visits, and number and length of admissions. Direct costs were analysed. We compared all variables between immigrant and Spanish patients. Immigrants represented 12% (n=43) of the cohort. There were no differences in the number of out-patient, ER, and day-care hospital visits per patient between both groups. The number of hospital admissions per patient for any cause was higher in immigrant than in Spanish patients, 1.3 (4.4) versus 0.9 (2.7), P=.034. A high proportion of visits, both for the immigrant (45.1%) and Spanish patients (43.0%), took place in services other than Infectious Diseases. Mean unitary cost per patient per admission, out-patient visits and ER visits were similar between groups. Pharmacy costs per year was higher in Spanish patients than in immigrants (7351.8 versus 7153.9 euros [year 2005], P=.012). There were no differences in the total cost per patient per year between both groups. The global distribution of cost was very similar between both groups; almost 75% of the total cost was attributed to pharmacy in both groups. There are no significant differences in health resource utilisation and associated costs between immigrant and Spanish HIV patients. Copyright © 2011 Elsevier España, S.L. All rights reserved.
Determination of sex from the patella in a contemporary Spanish population.
Peckmann, Tanya R; Meek, Susan; Dilkie, Natasha; Rozendaal, Andrew
2016-11-01
The skull and pelvis have been used for the determination of sex for unknown human remains. However, in forensic cases where skeletal remains often exhibit postmortem damage and taphonomic changes the patella may be used for the determination of sex as it is a preservationally favoured bone. The goal of the present research was to derive discriminant function equations from the patella for estimation of sex from a contemporary Spanish population. Six parameters were measured on 106 individuals (55 males and 51 females), ranging in age from 22 to 85 years old, from the Granada Osteological Collection. The statistical analyses showed that all variables were sexually dimorphic. Discriminant function score equations were generated for use in sex determination. The overall accuracy of sex classification ranged from 75.2% to 84.8% for the direct method and 75.5%-83.8% for the stepwise method. When the South African White discriminant functions were applied to the Spanish sample they showed high accuracy rates for sexing female patellae (90%-95.9%) and low accuracy rates for sexing male patellae (52.7%-58.2%). When the South African Black discriminant functions were applied to the Spanish sample they showed high accuracy rates for sexing male patellae (90.9%) and low accuracy rates for sexing female patellae (70%-75.5%). The patella was shown to be useful for sex determination in the contemporary Spanish population. Copyright © 2016 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.
Interface strategies in monolingual and end-state L2 Spanish grammars are not that different.
Parafita Couto, María C; Mueller Gathercole, Virginia C; Stadthagen-González, Hans
2014-01-01
This study explores syntactic, pragmatic, and lexical influences on adherence to SV and VS orders in native and fluent L2 speakers of Spanish. A judgment task examined 20 native monolingual and 20 longstanding L2 bilingual Spanish speakers' acceptance of SV and VS structures. Seventy-six distinct verbs were tested under a combination of syntactic and pragmatic constraints. Our findings challenge the hypothesis that internal interfaces are acquired more easily than external interfaces (Sorace, 2005, 2011; Sorace and Filiaci, 2006; White, 2006). Additional findings are that (a) bilinguals' judgments are less firm overall than monolinguals' (i.e., monolinguals are more likely to give extreme "yes" or "no" judgments) and (b) individual verbs do not necessarily behave as predicted under standard definitions of unaccusatives and unergatives. Correlations of the patterns found in the data with verb frequencies suggest that usage-based accounts of grammatical knowledge could help provide insight into speakers' knowledge of these constructs.
Espanol para el hispanolhablante (Spanish for the Spanish Speaker).
ERIC Educational Resources Information Center
Blanco, George M.
This guide provides Texas teachers and administrators with guidelines, goals, instructional strategies, and activities for teaching Spanish to secondary level native speakers. It is based on the principle that the Spanish speaking student is the strongest linguistic and cultural resource to Texas teachers of languages other than English, and one…
Coco, Laura; Colina, Sonia; Atcherson, Samuel R.
2017-01-01
Purpose The purpose of this study was to examine the readability level of the Spanish versions of several audiology- and otolaryngology-related patient-reported outcome measures (PROMs) and include a readability analysis of 2 translation approaches when available—the published version and a “functionalist” version—using a team-based collaborative approach including community members. Method Readability levels were calculated using the Fry Graph adapted for Spanish, as well as the Fernandez-Huerta and the Spaulding formulae for several commonly used audiology- and otolaryngology-related PROMs. Results Readability calculations agreed with previous studies analyzing audiology-related PROMs in English and demonstrated many Spanish-language PROMs were beyond the 5th grade reading level suggested for health-related materials written for the average population. In addition, the functionalist versions of the PROMs yielded lower grade-level (improved) readability levels than the published versions. Conclusion Our results suggest many of the Spanish-language PROMs evaluated here are beyond the recommended readability levels and may be influenced by the approach to translation. Moreover, improved readability may be possible using a functionalist approach to translation. Future analysis of the suitability of outcome measures and the quality of their translations should move beyond readability and include an evaluation of the individual's comprehension of the written text. PMID:28892821
Word Class Distinctions in Second Language Acquisition: An Experimental Study of L2 Spanish
ERIC Educational Resources Information Center
Zyzik, Eve; Azevedo, Clara
2009-01-01
Although the problem of word class has been explored in numerous first language studies, relatively little is known about this process in SLA. The present study measures second language (L2) learners' knowledge of word class distinctions (e.g., noun vs. adjective) in a variety of syntactic contexts. English-speaking learners of Spanish from…
I [image omitted] Spanish: K-8 Attitudes toward Learning Spanish with Computers
ERIC Educational Resources Information Center
Garcia-Villada, Eduardo
2011-01-01
This study investigates children's attitudes and technology use for learning Spanish, and examines the type of technology-enhanced learning activities they enjoy. A survey with two versions was developed to gather attitudes and opinions of 2,220 children in grades K-2 and 3-8 in eight small rural school districts in the Midwest of the United…
BODIPY-Conjugated Xyloside Primes Fluorescent Glycosaminoglycans in the Inner Ear of Opsanus tau.
Holman, Holly A; Tran, Vy M; Kalita, Mausam; Nguyen, Lynn N; Arungundram, Sailaja; Kuberan, Balagurunathan; Rabbitt, Richard D
2016-12-01
We report on a new xyloside conjugated to BODIPY, BX and its utility to prime fluorescent glycosaminoglycans (BX-GAGs) within the inner ear in vivo. When BX is administered directly into the endolymphatic space of the oyster toadfish (Opsanus tau) inner ear, fluorescent BX-GAGs are primed and become visible in the sensory epithelia of the semicircular canals, utricle, and saccule. Confocal and 2-photon microscopy of vestibular organs fixed 4 h following BX treatment, reveal BX-GAGs constituting glycocalyces that envelop hair cell kinocilium, nerve fibers, and capillaries. In the presence of GAG-specific enzymes, the BX-GAG signals are diminished, suggesting that chondroitin sulfates are the primary GAGs primed by BX. Results are consistent with similar click-xylosides in CHO cell lines, where the xyloside enters the Golgi and preferentially initiates chondroitin sulfate B production. Introduction of BX produces a temporary block of hair cell mechanoelectrical transduction (MET) currents in the crista, reduction in background discharge rate of afferent neurons, and a reduction in sensitivity to physiological stimulation. A six-degree-of-freedom pharmacokinetic mathematical model has been applied to interpret the time course and spatial distribution of BX and BX-GAGs. Results demonstrate a new optical approach to study GAG biology in the inner ear, for tracking synthesis and localization in real time.
ERIC Educational Resources Information Center
Bowen, J. Donald, Ed.; Ornstein, Jacob, Ed.
The Spanish dialects of the Southwest United States have received little serious attention until recently. The present volume contains studies designed to contribute to the understanding and acceptance of Southwest Spanish. The book consists of the following chapters: (1) "Linguistic Diversity in Southwest Spanish," by Garland D. Bills…
Hybrid Spanish Programs: A Challenging and Successful Endeavor
ERIC Educational Resources Information Center
Hermosilla, Luis
2014-01-01
Several types of hybrid Spanish programs have been developed in US colleges and universities for more than ten years, but the most common structure consists of a course in which the instruction combines face-to-face time with an instructor and the use of an online platform. Studies have demonstrated that a well-developed hybrid Spanish program can…
NASA Astrophysics Data System (ADS)
Zhao, Shuai; Yamamoto, Kumiko; Iikubo, Satoshi; Hayase, Shuzi; Ma, Tingli
2018-06-01
Organolead halide perovskite is regarded as the most promising light-harvesting material for next-generation solar cells; however, the intrinsic instability and toxicity of lead are still of great concern. Bismuth is ecofriendly and has electronic properties similar to those of lead, which has gradually attracted interest for optoelectronic applications. However, the valence state of bismuth is different from that of lead, eliminating the possibility of replacing lead by bismuth in organolead halide perovskites. To address this matter, one feasible strategy is to construct B-site double perovskites by the combination of Bi3+ and B+ in 1:1 ratio. In this work, lead-free halide double perovskites of the form Cs2NaBX6 (B = Sb, Bi; X = Cl, Br, I) were investigated by first-principles calculations. The electronic properties, optical absorption coefficients, and thermodynamic stability of these compounds were investigated to ascertain their potential application in solar energy conversion. The results provide theoretical support for the exploration of lead-free perovskite materials in potential optoelectronic applications.
Instruction in Spanish and Outcomes for Pre-Kindergarten English Language Learners. Research Brief
ERIC Educational Resources Information Center
Burchinal, Margaret; Field, Samuel; Lopez, Michael L.; Howes, Carollee; Pianta, Robert
2013-01-01
This study examined associations between classroom quality, amount of instruction in Spanish, and academic learning of Spanish-speaking 4 years-olds. Findings suggest that gains in reading and math were larger when children received more instruction in Spanish in classrooms with more responsive and sensitive teachers. It is possible that…
Martín-Fernández, Jesús; Ariza-Cardiel, Gloria; Polentinos-Castro, Elena; Sanz-Cuesta, Teresa; Sarria-Santamera, Antonio; Del Cura-González, Isabel
2017-09-25
To assess the burden of several determinants on health-related quality of life (HRQOL) and to study its heterogeneity among the different Spanish regions. Cross-sectional study. Data were obtained from the Spanish National Health Survey (2012), and HRQOL was measured using the EQ-5D-5L questionnaire (utility and visual analogue scale -VAS- scores). Demographic variables, physical health condition, social variables, mental health status, and lifestyle were also analysed. Tobit regression models were employed to study the relationships between expressed HRQOL and personal characteristics. A total of 20,979 surveys were obtained. Of them, 62.4% expressed a utility score of 1, corresponding to perfect health (95%CI: 61.8%-63.2%), and 54.2% showed VAS scores ≥80 (95%CI: 53.5%-54.9%). HRQOL was mainly described as a function of age, chronic limitation in daily activities, and mental health status. Belonging to a higher-class strata and physical activity were related to better self-perceived HRQOL. Ageing worsened perceived HRQOL, but did not influence its determinants, and differences in HRQOL by regions were also not significant after model adjustment. HRQOL perception in the Spanish population varied slightly depending on the measure used (utilities index or VAS). Age, chronic limitations in daily life, and mental health status best explained the variability in perception, and no meaningful differences in HRQOL perception among regions were found after adjustment. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.
ERIC Educational Resources Information Center
Casellas de Kelly, Maria del Rosario
A University of New Mexico program in Spanish for professionals began in 1981 as a Spanish and Portuguese program to provide language training for personnel in health care, business, law, and education. The program encountered early problems of uneven enrollments, funding difficulties, and some lack of interest from the campus professional schools…
Factors Influencing the Second Language Acquisition of Spanish Vibrants
ERIC Educational Resources Information Center
Hurtado, Luz Marcela; Estrada, Chelsea
2010-01-01
This article examines the role of linguistic and sociolinguistic factors in the second language (L2) acquisition of Spanish vibrants. The data consist of 2 sets of recordings from 37 students enrolled in a Spanish pronunciation class. The statistical program VarbRul was used to analyze 7,597 samples. The vibration (simple or multiple) and the…
Interactive-predictive detection of handwritten text blocks
NASA Astrophysics Data System (ADS)
Ramos Terrades, O.; Serrano, N.; Gordó, A.; Valveny, E.; Juan, A.
2010-01-01
A method for text block detection is introduced for old handwritten documents. The proposed method takes advantage of sequential book structure, taking into account layout information from pages previously transcribed. This glance at the past is used to predict the position of text blocks in the current page with the help of conventional layout analysis methods. The method is integrated into the GIDOC prototype: a first attempt to provide integrated support for interactive-predictive page layout analysis, text line detection and handwritten text transcription. Results are given in a transcription task on a 764-page Spanish manuscript from 1891.
Sickness presenteeism in Spanish-born and immigrant workers in Spain
2010-01-01
Background Previous studies have shown that immigrant workers face relatively worse working and employment conditions, as well as lower rates of sickness absence than native-born workers. This study aims to assess rates of sickness presenteeism in a sample of Spanish-born and foreign-born workers according to different characteristics. Methods A cross-sectional survey was conducted amongst a convenience sample of workers (Spanish-born and foreign-born), living in four Spanish cities: Barcelona, Huelva, Madrid and Valencia (2008-2009). Sickness presenteeism information was collected through two items in the questionnaire ("Have you had health problems in the last year?" and "Have you ever had to miss work for any health problem?") and was defined as worker who had a health problem (answered yes, first item) and had not missed work (answered no, second item). For the analysis, the sample of 2,059 workers (1,617 foreign-born) who answered yes to health problems was included. After descriptives, logistic regressions were used to establish the association between origin country and sickness presenteeism (adjusted odds ratios aOR; 95% confidence interval 95%CI). Analyses were stratified per time spent in Spain among foreign-born workers. Results All of the results refer to the comparison between foreign-born and Spanish-born workers as a whole, and in some categories relating to personal and occupational conditions. Foreign-born workers were more likely to report sickness presenteeism compared with their Spanish-born counterparts, especially those living in Spain for under 2 years [Prevalence: 42% in Spanish-born and 56.3% in Foreign-born; aOR 1.77 95%CI 1.24-2.53]. In case of foreign-born workers (with time in Spain < 2 years), men [aOR 2.31 95%CI 1.40-3.80], those with university studies [aOR 3.01 95%CI 1.04-8.69], temporary contracts [aOR 2.26 95%CI 1.29-3.98] and salaries between 751-1,200€ per month [aOR 1.74 95% CI 1.04-2.92] were more likely to report sickness
21 CFR 290.6 - Spanish-language version of required warning.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Spanish-language version of required warning. 290.6 Section 290.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CONTROLLED DRUGS General Provisions § 290.6 Spanish-language version of required...
Luque-Ramírez, M; Sanz de Burgoa, V
2018-06-08
To assess the cardiovascular risk according to the UKPDS risk engine; Framingham function and score comparing clinical characteristics of diabetes mellitus type 2 (DM2) patients according to their habits status. A descriptive analysis was performed. A total of 890 Spanish patients with DM2 (444 smokers and 446 former-smokers) were included in a cross-sectional, observational, epidemiological multicenter nationwide study. Coronary heart disease risk at 10 years was calculated using the UKPDS risk score in both patient subgroups. Results were also compared with the Spanish calibrated (REGICOR) and updated Framingham risk scores. The estimated likelihood of coronary heart disease risk at 10 years according to the UKPDS score was significantly greater in smokers compared with former-smokers. This increased risk was greater in subjects with poorer blood glucose control, and was attenuated in women ≥60 years-old. The Framingham and UKPDS scores conferred a greater estimated risk than the REGICOR equation in Spanish diabetics. Quitting smoke in patients with DM2 is accompanied by a significant decrease in the estimated risk of coronary events as assessed by UKPDS. Our findings support the importance of quitting smoking among diabetic patients in order to reduce cardiovascular risk. Copyright © 2018 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.
Low Temperature Extends the Lifespan of Bursaphelenchus xylophilus through the cGMP Pathway
Wang, Bowen; Ma, Ling; Wang, Feng; Wang, Buyong; Hao, Xin; Xu, Jiayao; Ma, Yan
2017-01-01
The causal agent of pine wilt disease, pine wood nematode (PWN) (Bursaphelenchus xylophilus), revealed extended lifespan at low temperature. To discover the molecular mechanism of this phenomenon, we attempted to study the molecular characterization, transcript abundance, and functions of three genes of the cyclic guanosine monophosphate (cGMP) pathway from B. xylophilus. Three cGMP pathway genes were identified from B. xylophilus. Bioinformatic software was utilized to analyze the characteristics of the three putative proteins. Function of the three genes in cold tolerance was studied with RNA interference (RNAi). The results showed that the deduced protein of Bx-DAF-11 has an adenylate and guanylate cyclase catalytic domain, indicating an ability to bind to extracellular ligands and synthesizing cGMP. Both Bx-TAX-2 and Bx-TAX-4 have cyclic nucleotide-binding domains and ion transport protein domains, illustrating that they are cGMP-gated ion channels. The transcript level of Bx-daf-11, Bx-tax-2, and Bx-tax-4 increased at low temperature. The survival rates of three gene silenced B. xylophilus revealed a significant decrease at low temperature. This study illustrated that the cGMP pathway plays a key role in low-temperature-induced lifespan extension in B. xylophilus. PMID:29099744
75 FR 34703 - Procurement List; Additions and Deletions
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-18
... gallon drum, 1 DR NSN: 7930-00-NIB-0555--BioRenewable Glass Cleaner, 2-liter, 4/BX NSN: 7930-00-NIB-0556--BioRenewable Glass Cleaner, 55 gallon drum, 1 DR NSN: 7930-00-NIB-0557--Neutral Disinfectant Cleaner...-NIB-0559--BioRenewable Industrial Cleaner, 2 liter, 4/ BX NSN: 7930-00-NIB-0560--BioRenewable...
Feasibility trial of a Spanish-language multimedia educational intervention.
Wells, Kristen J; McIntyre, Jessica; Gonzalez, Luis E; Lee, Ji-Hyun; Fisher, Kate J; Jacobsen, Paul B; Meade, Cathy; Muñoz-Antonia, Teresita; Quinn, Gwendolyn P
2013-10-01
Hispanic cancer patients are underrepresented in clinical trials; research suggests lack of knowledge and language barriers contribute to low accrual. Multimedia materials offer advantages to Hispanic populations because they have high acceptability, are easy to disseminate, and can be viewed with family. Hispanic cancer patients and caregivers participated in focus groups to aid in developing a Spanish-language multimedia intervention to educate Hispanic cancer patients about clinical trials. We explored the feasibility of delivering the intervention in medical oncology clinics. A total of 35 patients were randomized to either the multimedia intervention group (n = 18) or a control group (n = 17) who were asked to read the National Cancer Institute's Spanish-language clinical trials brochure. Self-reported data on knowledge about and attitudes toward clinical trials, self-efficacy for participating in a clinical trial, intention to participate in a clinical trial if asked, and receptivity to information about a clinical trial were collected at baseline and 10 days later. Delivery of the multimedia presentation in oncology clinics was feasible. The intervention group had more knowledge about clinical trials at follow-up than the control group; scores for intention to participate in a clinical trial by participants in the intervention group increased from 3.8 to 4.0 of a possible 5, but declined in the control group from 4.5 to 4.1. No statistically significant difference was detected between groups in scores for attitudes or self-efficacy for making a decision to participate in a clinical trial. Our sample size was inadequate to identify differences between the informational methods. Although all patients were asked about their willingness to participate in a clinical trial, this decision was hypothetical. In addition, the study was conducted with a sample of Spanish-speaking Hispanic cancer patients at a comprehensive cancer center in Florida. Thus, the results
Cuesta-Vargas, Antonio Ignacio; González-Sánchez, Manuel
2014-10-29
Spanish is one of the five most spoken languages in the world. There is currently no published Spanish version of the Örebro Musculoskeletal Pain Questionnaire (OMPQ). The aim of the present study is to describe the process of translating the OMPQ into Spanish and to perform an analysis of reliability, internal structure, internal consistency and concurrent criterion-related validity. Translation and psychometric testing. Two independent translators translated the OMPQ into Spanish. From both translations a consensus version was achieved. A backward translation was made to verify and resolve any semantic or conceptual problems. A total of 104 patients (67 men/37 women) with a mean age of 53.48 (±11.63), suffering from chronic musculoskeletal disorders, twice completed a Spanish version of the OMPQ. Statistical analysis was performed to evaluate the reliability, the internal structure, internal consistency and concurrent criterion-related validity with reference to the gold standard questionnaire SF-12v2. All variables except "Coping" showed a rate above 0.85 on reliability. The internal structure calculation through exploratory factor analysis indicated that 75.2% of the variance can be explained with six components with an eigenvalue higher than 1 and 52.1% with only three components higher than 10% of variance explained. In the concurrent criterion-related validity, several significant correlations were seen close to 0.6, exceeding that value in the correlation between general health and total value of the OMPQ. The Spanish version of the screening questionnaire OMPQ can be used to identify Spanish patients with musculoskeletal pain at risk of developing a chronic disability.
Developmental Screening Disparities for Languages Other than English and Spanish.
Knuti Rodrigues, Kristine; Hambidge, Simon J; Dickinson, Miriam; Richardson, Douglas B; Davidson, Arthur J
2016-01-01
Limited English proficiency (LEP) is a known barrier to preventive care. Children from families with LEP face socioeconomic circumstances associated with increased odds of developmental delays and decreased participation in early care and education programs. Little is known about developmental surveillance and screening for children from families who speak languages other than English and Spanish. We sought to compare developmental surveillance and screening at well-child visits (WCVs) by preferred parental language. Using a retrospective cohort (n = 15,320) of children aged 8 to 40 months with ≥2 WCVs from January 1, 2006, to July 1, 2010, in a community health system, 450 children from 3 language groups (150 English, 150 Spanish, and 150 non-English, non-Spanish) were randomly selected. Chart review assessed 2 primary outcomes, developmental surveillance at 100% of WCVs and screened with a standardized developmental screening tool, and also determined whether children were referred for diagnostic developmental evaluation. Bivariate and multiple logistic regression analyses were conducted. Compared to the English-speaking group, the non-English, non-Spanish group had lower odds of receiving developmental surveillance at 100% of WCVs (odds ratio, 0.3; 95% confidence interval, 0.2, 0.5) and of being screened with a standardized developmental screening tool (odds ratio, 0.1; 95% confidence interval, 0.1, 0.2). There were no differences between the English- and Spanish-speaking groups. Though underpowered, no differences were found for referral. Improved developmental surveillance and screening are needed for children from families who speak languages other than English and Spanish. Lack of statistically significant differences between English- and Spanish-speaking groups suggests that improved translation and interpretation resources may decrease disparities. Copyright © 2016 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.
Stent design favorably influences the vascular response in normal porcine coronary arteries.
Carter, A J; Scott, D; Rahdert, D; Bailey, L; De Vries J; Ayerdi, K; Turnlund, T; Jones, R; Virmani, R; Fischell, T A
1999-03-01
The purpose of this study was to compare the arterial response following implantation of a stainless-steel, balloon-expandable, tubular slotted stent with that of a novel computer-designed, multi-cellular stent in normal porcine coronary arteries. Intracoronary stent placement has evolved into the primary strategy for percutaneous revascularization of symptomatic coronary arterial lesions. Presently there is intense interest in developing new stent designs to improve stent delivery and biocompatability. Computer-assisted design was utilized to develop a balloon-expandable stent with symmetric expansion properties, uniform arterial wall coverage, longitudinal flexibility and radial strength. Quantitative coronary angiography and histological assessment of the stented arteries was used to evaluate the acute and chronic vascular responses to a stainless-steel, balloon-expandable, tubular slotted stent as compared to the computer-designed BX stent in the normolipemic swine. Forty stents (24 BX, 16 tubular slotted) were implanted in 19 miniature swine at a mean inflation pressure of 9 atm using identical delivery systems. Eight of the BX and none of the tubular slotted stents were post-dilated with a non-compliant balloon at 12-14 atm. The mean stent-to-artery ratio was similar for the BX (1.03 +/- 0.06) and tubular slotted (1.04 +/- 0.11; p = 0.59) designs. Protrusion or asymmetric radial flaring of a strut at the stent margin was present in 1 of 23 BX stents (4.3%) and 10 of 15 tubular slotted stents (66.7%; p < 0.0001). The mean arterial injury score was significantly less for the BX stent (0.2 +/- 0.2) as compared with the tubular slotted stents (0.4 +/- 0.4; p = 0.025). At 3 days, thrombus area was similar for the BX and tubular slotted designs (0.42 +/- 0.16 mm2 versus 0.44 +/- 0.18 mm2, respectively; p = 0.88). The mean neointimal area was significantly less for the BX at 2 months (1.09 +/- 0.25 mm2 versus 2.93 +/- 2.26 mm2 in the tubular slotted stent) and at 6
Perception of a Regional Spanish Sound: The Case of /s/-Weakening
ERIC Educational Resources Information Center
George, Angela
2014-01-01
While taking foreign language classes or interacting in the target language community, language learners will be exposed to dialectal differences. This paper addresses how adult learners of Spanish in beginning, intermediate, and advanced Spanish courses at a large US university perceived a common sociolinguistic feature of Spanish, /s/-weakening,…
Segmental and Intonational Evidence for a Los Angeles Chicano Spanish Vernacular
ERIC Educational Resources Information Center
Andrade, Argelia
2012-01-01
This dissertation has two complementary objectives. First, the present study provides a contemporary reading of "hispanista" research about Mexican Spanish, including Chicano Spanish. In addition, this dissertation presents an overview and analysis of intonational findings of both Mexican Spanish (from the Los Altos region in Jalisco)…
How Fair Is College Financing that Speaks Spanish First?
ERIC Educational Resources Information Center
Allen, Kerri
2007-01-01
2Futuro is a new "Spanish-first" college-financing program rolled out by Sallie Mae and USA Funds. The pilot version of 2Futuro launched last summer and is, say its partnering agents, "the only fully bilingual college-financing and outreach program that enables Hispanic parents and students to apply for college loans in Spanish. By the end of the…
Customized weight curves for Spanish fetuses and newborns.
González González, Nieves Luisa; González Dávila, Enrique; Cabrera, Francisco; Padrón, Erika; Castro, José Ramon; García Hernández, José Angel
2014-09-01
To construct a model of customized birthweight curves for use in a Spanish population. Data of 20 331 newborns were used to construct a customized birthweight model. Multiple regression analysis was performed with newborn weight as the dependent variable and gestational age (GA), sex and maternal (M) weight, height, parity and ethnic origin as the independent variables. Using the new model, 27,507 newborns were classified as adequate for GA (AGA), large for GA (LGA) or small for GA (SGA). The results were compared with those of other customized and non-customized models. The resulting formula for the calculation of optimal neonatal weight was: Optimum weight (g) = 3289.681 + 135.413*GA40-14.063*GA40(2)-0.838*GA40(3) + 113.889 (if multiparous) + 165.560 (if origin = Asia) + 161.550 (South America) + 67.927 (rest of Europe) +109.265 (North Africa) + 9.392*Maternal-Height + 4.856*Maternal-Weight-0.098*Maternal-Weight(2) + 0.001*Maternal-Weight(3) + 67.188*Sex + GA40*(6.890*Sex + 9.032 (If multiparous) +0.006*Maternal-Height(3) + 0.260*Maternal-Weight) + GA40(2) (-0.378*Maternal-Height - 0.008*Maternal-Height(2)) + GA40(3) (-0.032*Maternal-Height). Weight percentiles were obtained from standard data using optimum weight variation coefficient. Agreement between our customized model and other Spanish models was "good" (κ = 0.717 and κ = 0.736; p < 0.001). Our model is comparable to other Spanish models, but offers the advantage of being customized, updated and freely available on the web. The 30.6% of infants classified as SGA using our model would be considered as AGA following a non-customized model.
History through First-Year Secondary School Spanish Textbooks: A Content Analysis
ERIC Educational Resources Information Center
Holley-Kline, Sam
2013-01-01
Although enrollments in secondary school Spanish have risen over the past few decades, the Spanish-speaking world (Latin America, in particular) tends to be underrepresented or absent in history textbooks. Given that not all students who take entry-level Spanish classes will continue to more advanced levels, the first-year Spanish textbook may be…
ERIC Educational Resources Information Center
Thompson, Lewin, and Associates, Inc., Washington, DC.
This report summarizes the findings and recommendations of a study conducted cooperatively by a management consulting firm and a team of Spanish-speaking manpower specialists. Basic issues explored were: (1) What are the manpower needs of Spanish-speaking Americans, (2) How are manpower programs meeting the needs at present, and (3) What action…
Garcimartin, Paloma; Pardo-Cladellas, Yolanda; Verdú-Rotellar, Jose-Maria; Delgado-Hito, Pilar; Astals-Vizcaino, Monica; Comin-Colet, Josep
2017-12-22
To describe the process of translation and cultural adaptation of the Patient empowerment in long-term condition to the Spanish language. Translation, cross-cultural adaptation, and pilot testing (cognitive debriefing) LOCATION: Primary and Hospital care. Ten patients admitted to a cardiology department of a University Hospital MAIN MEASUREMENTS: 1) Direct translation, 2) conciliation and synthesis of the versions by expert panel, 3) back- translation, 4) agreement on the back-translated version with the author of the original version, 5) analysis of comprehensibility through cognitive interviews. There were no differences between the direct-translated versions. The expert panel introduced changes in 23 out of the 47 items of the questionnaire. The author of the original version agreed with the version of the back-translation. In the cognitive interviews, patients reported high difficulty in one item and low difficulty in 4. The Spanish version of the Patient Empowerment in long-term conditions questionnaire is semantically and conceptually equivalent to the original tool. The assessment of the psychometric properties of the Spanish version of the questionnaire will be carried out at a later stage. Copyright © 2017 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.
Sanchez-Garcia, Manuel; Extremera, Natalio; Fernandez-Berrocal, Pablo
2016-11-01
This research examined evidence regarding the reliability and validity of scores on the Spanish version of the Mayer-Salovey-Caruso Emotional Intelligence Test, Version 2.0 (MSCEIT; Mayer, Salovey, & Caruso, 2002). In Study 1, we found a close convergence of the Spanish consensus scores and the general and expert consensus scores determined with Mayer, Salovey, Caruso, and Sitarenios (2003) data. The MSCEIT also demonstrated adequate evidence of reliability of test scores as estimated by internal consistency and test-retest correlation after 12 weeks. Confirmatory factor analysis supported a 3-level higher factor model with 8 manifest variables (task scores), 4 first-level factors (corresponding to the 4-branch model of Mayer & Salovey [1997], with 2 tasks for each branch), 2 second-level factors (experiential and strategic areas, with 2 branches for each area), and 1 third-level factor (overall emotional intelligence [EI]), and multigroup analyses supported MSCEIT cross-gender invariance. Study 2 found evidence for the discriminant validity of scores on the MSCEIT subscales, which were differentially related to personality and self-reported EI. Study 3 provided evidence of the incremental validity of scores on the MSCEIT, which added significant variance to the prospective prediction of psychological well-being after controlling for personality traits. The psychometric properties of the Spanish MSCEIT are similar to those of the original English version, supporting its use for assessing emotional abilities in the Spanish population. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Godcharles, M.F.; Murphy, M.D.
1986-06-01
This Species Profile on king and Spanish mackerel summarizes the taxonomy, morphology, distribution, life history, fishery descriptions, ecological role, and environmental requirements of these coastal pelagic fish to assist environmental impact assessment. King and Spanish mackerel support major commercial and sport fisheries in south Florida. In 1974 to 1983, Gulf of Mexico and Atlantic commercial landings of king mackerel declined from 10.4 to 4.3 million lb.; Spanish mackerel have fluctuated between 4.9 to 17.4 million lb. Both inhabit coastal waters, but Spanish mackerel are generally found closer to beaches and in outer estuarine waters. Both species feed principally on estuarine-dependentmore » species. They are highly migratory, exhibiting seasonal migrations to winter feeding grounds off south Florida and summer spawning/feeding grounds in the northern Gulf of Mexico and off the Atlantic coast of the Southeastern US. Spawning occurs from March/April through September/October between the middle and Outer Continental Shelf (35 to 183 mi) for king mackerel and the inner shelf (12 to 34 mi) for Spanish mackerel. King mackerel reach sexual maturity in their 3rd and 4th years and Spanish, between their 2nd and 3rd. Female king mackerel live longer and grow larger and faster than males. Spanish mackerel live to 8 years; females also grow faster than males. King and Spanish mackerel feed principally on schooling fishes. Larvae and juveniles of both species are prey to little tunny and dolphin; adults are prey for sharks and bottlenose dolphin. Temperature and salinity are important factors regulating mackerel distribution.« less
Spanish Cultural Adaptation of the Questionnaire Early Arthritis for Psoriatic Patients.
García-Gavín, J; Pérez-Pérez, L; Tinazzi, I; Vidal, D; McGonagle, D
2017-12-01
The Early Arthritis for Psoriatic patients (EARP) questionnaire is a screening tool for psoriatic arthritis. The original Italian version has good measurement properties but the EARP required translation and adaptation for use in Spain. This article describes the cultural adaptation process as a step prior to validation. We used the principles of good practice for the cross-cultural adaptation of patient-reported outcomes measurement established by the International Society Pharmacoeconomics and Outcome Research. The steps in this process were preparation, forward translation, reconciliation, back-translation and review, harmonization, cognitive debriefing and review, and proofreading. During preparation the developers of the original questionnaire were asked for their permission to adapt the EARP for use in Spain and to act as consultants during the process. The original questionnaire was translated into Spanish by native Spanish translators, who made slight changes that were approved by the questionnaire's developers. The Spanish version was then back-translated into Italian; that version was reviewed to confirm equivalence with the original Italian text. The reconciled Spanish EARP was then tested for comprehensibility and interpretation in a group of 35 patients. All the patients answered all items without making additional comments. This cultural adaptation of the EARP questionnaire for Spanish populations is the first step towards its later use in routine clinical practice. The application of a cross-cultural adaptation method ensured equivalence between the original and Spanish versions of the EARP. The Spanish questionnaire will be validated in a second stage. Copyright © 2017 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.
Gonzalez, Laura; Negrón, Rosalyn; Berry, Donna L.
2014-01-01
Spanish speakers in the United States encounter numerous communication barriers during cancer treatment. Communication-focused interventions may help Spanish speakers communicate better with healthcare providers and manage symptoms and quality of life issues (SQOL). For this study, we developed a Spanish version of the electronic self-report assessment for cancer (ESRA-C), a web-based program that helps people with cancer report, track, and manage cancer-related SQOL. Four methods were used to evaluate the Spanish version. Focus groups and cognitive interviews were conducted with 51 Spanish-speaking individuals to elicit feedback. Readability was assessed using the Fry readability formula. The cultural sensitivity assessment tool was applied by three bilingual, bicultural reviewers. Revisions were made to personalize the introduction using a patient story and photos and to simplify language. Focus group participants endorsed changes to the program in a second round of focus groups. Cultural sensitivity of the program was scored unacceptable (x¯=3.0) for audiovisual material and acceptable (x¯=3.0) for written material. Fry reading levels ranged from 4th to 10th grade. Findings from this study provide several next steps to refine ESRA-C for Spanish speakers with cancer. PMID:25045535
The Role of Gender, Embedded Questions, and Domain Specific Readings with Learners of Spanish
ERIC Educational Resources Information Center
Brantmeier, Cindy; Callender, Aimee; McDaniel, Mark
2013-01-01
The present study utilizes readings taken from texts in social psychology to examine the effects by gender of embedded "what" questions and elaborative "why" questions on reading comprehension. During regular class time, 97 advanced second language (L2) learners of Spanish read two different vignettes, either with or without…
Speaking with (Dis)respect: A Study of Reactions to Mock Spanish
ERIC Educational Resources Information Center
Callahan, Laura
2010-01-01
This paper reports on an investigation into the reactions of 147 participants of various ethnicities to a language practice in the USA that has been characterized as Mock Spanish, a special register in which Spanish words or phrases are used to evoke humor by indexing an often unflattering image of Spanish speakers. Research questions include…
ERIC Educational Resources Information Center
Balam, Osmer; de Prada Pérez, Ana
2017-01-01
Through the analysis of survey and interview data, we investigated the attitudes and perceptions of 32 multilingual teachers of Spanish in Belize, a code-switching (CS) context where Spanish is in intense contact with English and Belizean Kriol. More specifically, we examined teachers' and students' attitudes toward Spanish and CS and teachers'…
Overview of Spanish and Latin American Distance Higher Education.
ERIC Educational Resources Information Center
Garcia Garrido, Jose Luis
1991-01-01
Provides a brief overview of Spanish and Latin American distance education programs for higher education and describes the three most important institutions: (1) the Spanish UNED (Universidad Nacional de Educacion a Distancia); (2) the Costa Rican UNED (Universidad Estatal a Distancia); and (3) the Venezuelan UNA (Universidad Nacional Abierta).…
Park, Juyoung; Newman, David; McCaffrey, Ruth; Garrido, Jacinto J; Riccio, Mary Lou; Liehr, Patricia
Chair yoga (CY), a mind-body therapy, is a safe nonpharmacological approach for managing osteoarthritis (OA) in older adults who cannot participate in standing exercise. However, there is no linguistically tailored CY program for those with limited English proficiency (LEP). This 2-arm randomized controlled trial compared the effects of a linguistically tailored yoga program (English and Spanish versions) on the outcomes of pain, physical function, and psychosocial factors compared to the effects of a linguistically tailored Health Education Program (HEP; English and Spanish versions). Participants with lower-extremity OA, recruited from 2 community sites, completed the Spanish (n = 40) or English (n = 60) version of twice-weekly 45-min CY or HEP sessions for 8 weeks. Data were collected at baseline, 4 weeks, 8 weeks, and 1- and 3-month follow-ups. English and Spanish CY groups (but neither HEP language group) showed significant decreases in pain interference. Measures of OA symptoms, balance, depression, and social activities were not significantly different between English and Spanish versions of CY and English and Spanish versions of HEP. It was concluded that the Spanish and English versions of CY and HEP were equivalent. Linguistically tailored CY could be implemented in aging-serving communities for persons with LEP.
Lahuerta, Celia; Guirola, José A; Esteban, Enrique; Urbano, José; Laborda, Alicia; De Gregorio, Miguel Ángel
2017-07-01
We analyzed the scientific production of members of the Spanish Society of Vascular and Interventional Radiology (SERVEI) from 2010 to 2015. We retrospectively analyzed the indexed scientific productivity of all SERVEI members for the last 6 years as measured by bibliometric indexes. Different databases were used (e.g., PubMed, Scopus, Web of Knowledge) to retrieve the total number of publications, number of citations, and h-index. Every article was assigned the impact factor of its publication year and its corresponding quartile according to Journal Citation Reports. The relationships between all of these parameters and the Spanish region, the gender and age of the interventional radiologists (IRs), and their connection to the university environment were also studied. A total of 519 scientific articles from 247 SERVEI members working in 118 Spanish hospitals were included, an average of 0.3 articles per interventionist/year. Most of the manuscripts were published in impact journals (52.2%) and placed in the lowest quartile (Q4). Navarre, Aragon, and Catalonia were the regions with the highest publication rate during the period studied (1.7, 0.92, and 0.6 publications per interventionist/year, respectively). Only 57 articles (12.6%) were published in 11 of the 125 journals under the category of Radiology, Nuclear Medicine, and Medical Imaging according to JCR. The scientific production of the Spanish IRs in the last 6 years is difficult to interpret. However, more than 50% of IRs published one article in the last 6 years. Finally, it would be advisable to repeat this study over a period of time in order to compare.
ERIC Educational Resources Information Center
Gildersleeve-Neumann, Christina E.; Kester, Ellen S.; Davis, Barbara L.; Pena, Elizabeth D.
2008-01-01
Purpose: English speech acquisition by typically developing 3- to 4-year-old children with monolingual English was compared to English speech acquisition by typically developing 3- to 4-year-old children with bilingual English-Spanish backgrounds. We predicted that exposure to Spanish would not affect the English phonetic inventory but would…
A Survey of Meaning Discrimination in Selected English/Spanish Dictionaries.
ERIC Educational Resources Information Center
Powers, Michael D.
1985-01-01
Examines the treatment of sense discrimination in eight Spanish/English English/Spanish bilingual dictionaries and one specialized dictionary. Does this by analyzing 30 words that Torrents des Prats determined have at least nine different sense discriminations from English into Spanish. Larousse was found to be far superior to the others. (SED)
Spanish for Heritage Speakers: A Statewide Survey of Secondary School Teachers
ERIC Educational Resources Information Center
Bateman, Blair E.; Wilkinson, Sara L.
2010-01-01
Although much attention has been given in recent literature to the teaching of Spanish as a heritage language (HL), few studies have been published on specific Spanish HL programs, especially in states such as Utah that have only recently seen a large increase in the number of heritage students of Spanish. This study reports the results of a…
NASA Astrophysics Data System (ADS)
Kwiatkowski, G.; Leble, S.
2014-03-01
Analytical form of quantum corrections to quasi-periodic solution of Sine-Gordon model and periodic solution of phi4 model is obtained through zeta function regularisation with account of all rest variables of a d-dimensional theory. Qualitative dependence of quantum corrections on parameters of the classical systems is also evaluated for a much broader class of potentials u(x) = b2f(bx) + C with b and C as arbitrary real constants.
The Real World Spanish Cassette Program. Script Book.
ERIC Educational Resources Information Center
Sternburg, Sheldon G.
This dual cassette program, accompanied by a script book, is designed to give students listening practice in Spanish, particularly for regional differences of pronunciation and for variety in idiomatic construction. The program may be integrated with texts used in intermediate and advanced levels of instruction. The announcements, jingles, and…
Processing ser and estar to locate objects and events: An ERP study with L2 speakers of Spanish.
Dussias, Paola E; Contemori, Carla; Román, Patricia
2014-01-01
In Spanish locative constructions, a different form of the copula is selected in relation to the semantic properties of the grammatical subject: sentences that locate objects require estar while those that locate events require ser (both translated in English as 'to be'). In an ERP study, we examined whether second language (L2) speakers of Spanish are sensitive to the selectional restrictions that the different types of subjects impose on the choice of the two copulas. Twenty-four native speakers of Spanish and two groups of L2 Spanish speakers (24 beginners and 18 advanced speakers) were recruited to investigate the processing of 'object/event + estar/ser ' permutations. Participants provided grammaticality judgments on correct (object + estar ; event + ser ) and incorrect (object + ser ; event + estar ) sentences while their brain activity was recorded. In line with previous studies (Leone-Fernández, Molinaro, Carreiras, & Barber, 2012; Sera, Gathje, & Pintado, 1999), the results of the grammaticality judgment for the native speakers showed that participants correctly accepted object + estar and event + ser constructions. In addition, while 'object + ser ' constructions were considered grossly ungrammatical, 'event + estar ' combinations were perceived as unacceptable to a lesser degree. For these same participants, ERP recording time-locked to the onset of the critical word ' en ' showed a larger P600 for the ser predicates when the subject was an object than when it was an event (*La silla es en la cocina vs. La fiesta es en la cocina). This P600 effect is consistent with syntactic repair of the defining predicate when it does not fit with the adequate semantic properties of the subject. For estar predicates (La silla está en la cocina vs. *La fiesta está en la cocina), the findings showed a central-frontal negativity between 500-700 ms. Grammaticality judgment data for the L2 speakers of Spanish showed that beginners were significantly less accurate than
Grandes, Gonzalo; Bully, Paola; Martinez, Catalina; Gagnon, Marie-Pierre
2017-11-10
Organizational readiness to change healthcare practice is a major determinant of successful implementation of evidence-based interventions. However, we lack of comprehensive, valid, and reliable instruments to measure it. We assessed the validity and reliability of the Spanish version of the Organizational Readiness for Knowledge Translation (OR4KT) questionnaire in the context of the implementation of the Prescribe Vida Saludable III project, which seeks to strengthen health promotion and chronic disease prevention in primary healthcare organizations of the Osakidetza (Basque Health Service, Spain). A cross-sectional study was conducted including 127 professionals from 20 primary care centers within Osakidetza. They filled in the OR4KT questionnaire twice in a 15- to 30-day period to test repeatability. In addition, we used the Survey of Organizational Attributes for Primary Care (SOAPC) and we documented the number of healthcare professionals who formally engaged in the Prescribe Vida Saludable III project within each participating center to assess concurrent validity. Cronbach's alpha for the overall OR4KT was .95, and the overall repeatability coefficient was 6.95%, both excellent results. Confirmatory factor analysis supported the underlying theoretical structure of 6 dimensions and 23 sub-dimensions. There were positive moderate-to-high internal correlations between these six dimensions, and there was evidence of good concurrent validity (correlation coefficient of .76 with SOAPC, and .80 with the proportion of professionals engaged by center). A score higher than 64 (out of 100) would be indicative of an organization with high level of readiness to implement the intervention (sensitivity = .75, specificity = 1). The Spanish version of the OR4KT exhibits very strong reliability and good validity, although it needs to be validated in a larger sample and in different implementation contexts.
A Gesture Inventory for the Teaching of Spanish.
ERIC Educational Resources Information Center
Green, Jerald R.
Intended for the nonnative, audiolingual-oriented Spanish teacher, this guide discusses the role of nonverbal behavior in foreign language learning with major emphasis given to an inventory of peninsular Spanish gesture. Gestures are described in narrative with line drawings to provide visual cues, and are accompanied by illustrative selections…
Growth rate dependence of boron incorporation into BxGa1-xAs layers
NASA Astrophysics Data System (ADS)
Detz, H.; MacFarland, D.; Zederbauer, T.; Lancaster, S.; Andrews, A. M.; Schrenk, W.; Strasser, G.
2017-11-01
This work provides a comprehensive study of the incorporation behavior of B in growing GaAs under molecular beam epitaxy conditions. Structural characterization of superlattices revealed a strong dependence of the BAs growth rate on the GaAs growth rate used. In general, higher GaAs growth rates lead to a higher apparent BAs growth rate, although lower B cell temperatures showed saturation behavior. Each B cell temperature requires a minimum GaAs growth rate for producing smooth films. The B incorporation into single thick layers was found to be reduced to 75-80% compared to superlattice structures. The p-type carrier densities in 1000 nm thick layers were found to be indirectly proportional to the B content. Furthermore, 500 nm thick BxGa1-xAs layers showed significantly lower carrier concentrations, indicating B segregation on the surface during growth of thicker layers.
Writing Disabilities in Spanish-Speaking Children: Introduction to the Special Series.
Jiménez, Juan E
This special issue of the Journal of Learning Disabilities focuses on studies of writing disabilities in Spanish-speaking children. The World Health Organization (2001) included writing difficulties as one of the problems considered to constitute an impediment to school participation, a significant element in the normal developmental process of the child. In this introduction, I describe the background of a larger project promoted by the United Nations Educational, Scientific and Cultural Organization (UNESCO). This special series offers recent findings on writing disabilities in Spanish-Speaking children within the UNESCO project. The pilot study was carried out in the Canary Islands, an autonomous Spanish region located between three continents and composed of seven islands in the Atlantic Ocean. Most of the current empirical evidence on writing disabilities comes from English, a language with deep orthography; therefore, it is very relevant to investigate the writing process in Spanish, a language with shallow, fine-grained orthography. Included are a number of articles that form a conspectus on writing disabilities in the Spanish language. Topics center on early grade writing assessment, prevalence of writing disabilities, handwriting and keyboarding, transcription and text generation, graphonomic and handwriting analysis, and instructional practices with an learning disabled population.
The horizontal and vertical attributes of individualism and collectivism in a Spanish population.
Gouveia, Valdiney V; Clemente, Miguel; Espinosa, Pablo
2003-02-01
The authors examined the dimensionality and factorial structure of individualism and collectivism in Spanish participants (N = 526). A series of confirmatory factor analyses were performed on responses to the 32-item individualism-collectivism measure reported by T. M. Singelis, H. C. Triandis, D. S. Bhawuk, and M. Gelfand (1995). Consistent with earlier data, the best fitting model was multidimensional: a vertical versus a horizontal attribute crossed with individualism and collectivism dimensions. Whereas the overall fit of the data to a LISREL model was moderate, additional self-report data on respondents' interpersonal experiences supported the construct validity of the 4 factors. The authors suggest that the additional complexity is useful in explaining Spanish social behavior.
Reaching Spanish-speaking smokers online: a 10-year worldwide research program
Muñoz, Ricardo Felipe; Chen, Ken; Bunge, Eduardo Liniers; Bravin, Julia Isabela; Shaughnessy, Elizabeth Annelly; Pérez-Stable, Eliseo Joaquín
2014-01-01
Objective To describe a 10-year proof-of-concept smoking cessation research program evaluating the reach of online health interventions throughout the Americas. Methods Recruitment occurred from 2002–2011, primarily using Google.com AdWords. Over 6 million smokers from the Americas entered keywords related to smoking cessation; 57 882 smokers (15 912 English speakers and 41 970 Spanish speakers) were recruited into online self-help automated intervention studies. To examine disparities in utilization of methods to quit smoking, cessation aids used by English speakers and Spanish speakers were compared. To determine whether online interventions reduce disparities, abstinence rates were also compared. Finally, the reach of the intervention was illustrated for three large Spanish-speaking countries of the Americas—Argentina, Mexico, and Peru—and the United States of America. Results Few participants had utilized other methods to stop smoking before coming to the Internet site; most reported using no previous smoking cessation aids: 69.2% of Spanish speakers versus 51.8% of English speakers (P < 0.01). The most used method was nicotine gum, 13.9%. Nicotine dependence levels were similar to those reported for in-person smoking cessation trials. Overall observed quit rate for English speakers was 38.1% and for Spanish speakers, 37.0%; quit rates in which participants with missing data were considered to be smoking were 11.1% and 10.6%, respectively. Neither comparison was significantly different. Conclusions The systematic use of evidence-based Internet interventions for health problems could have a broad impact throughout the Americas, at little or no cost to individuals or to ministries of health. PMID:25211569
Pilatti, Angelina; Lozano, Oscar M; Cyders, Melissa A
2015-12-01
The present study was aimed at determining the psychometric properties of the Spanish version of the UPPS-P Impulsive Behavior Scale in a sample of college students. Participants were 318 college students (36.2% men; mean age = 20.9 years, SD = 6.4 years). The psychometric properties of this Spanish version were analyzed using the Rasch model, and the factor structure was examined using confirmatory factor analysis. The verification of the global fit of the data showed adequate indexes for persons and items. The reliability estimates were high for both items and persons. Differential item functioning across gender was found for 23 items, which likely reflects known differences in impulsivity levels between men and women. The factor structure of the Spanish version of the UPPS-P replicates previous work with the original UPPS-P Scale. Overall, results suggest that test scores from the Spanish version of the UPPS-P show adequate psychometric properties to accurately assess the multidimensional model of impulsivity, which represents the most exhaustive measure of this construct. (c) 2015 APA, all rights reserved).
Acquiring Spanish at the Interfaces: An Integrative Approach to the L2 Acquisition of Psych-Verbs
ERIC Educational Resources Information Center
Gomez Soler, Inmaculada
2012-01-01
This dissertation provides a comprehensive analysis of the L2 acquisition of Spanish psych-verbs (e.g. "gustar" "to like") across four different proficiency levels. In particular, psych-verbs constitute a testing ground for the predictions of the Interface Hypothesis (Sorace and Filiaci, 2006; Tsimpli, Sorace, Heycok &…