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W.T. Wallace and A.S. Jeevarajan

inflammatory response of alveolar epithelial cells, A549 cells were exposed to ... Cellular Toxicity: A549 cells were grown in 12-well plates for 72 hours. ...

NASA Website

2
M t i Bi h iM t i Bi h i Experimental Techniques in BiophysicsExperimental Techniques in Biophysics

imaging: contact mode AFM image of a human alveolar epithelial cell (A549) in culture Topographic image Error image #12;AFM imaging � contact modeg g human alveolar epithelial cell (A549) in culture #12;AFM imaging curves on ...

E-print Network

3
A549 Lung Epithelial Cells Grown as Three-Dimensional Aggregates: Alternative Tissue Culture Model for Pseudomonas aeruginosa Pathogenesis
2005-02-01

A three-dimensional (3-D) lung aggregate model was developed from A549 human lung epithelial cells by using a rotating-wall vessel bioreactor to study the interactions between Pseudomonas aeruginosa and lung epithelial cells. The suitability of the 3-D aggregates as an ...

PubMed Central

4
TNF-?-stimulated macrophages protect A549 lung cells against iron and oxidation.
2011-07-01

Previously, we have shown that TNF-? protects iron-exposed J774 macrophages against iron-catalyzed oxidative lysosomal disruption and cell death by increasing reduced glutathione and H-ferritin in cells. Because J774 cells are able to harbor large amounts of iron, which is potentially harmful in a redox-active state, we hypothesized ...

PubMed

5
Human primary bronchial epithelial cells respond differently to titanium dioxide nanoparticles than the lung epithelial cell lines A549 and BEAS-2B.
2011-07-25

Abstract We have compared the cellular uptake and responses of five preparations of nanocrystalline titanium dioxide (TiO(2)) between normal human bronchial epithelial (NHBE) cells and epithelial cell lines (A549 and BEAS-2B). The P25 nanoparticles, containing both anatase ...

PubMed

6
Mineral fiber-mediated activation of phosphoinositide-specific phospholipase c in human bronchoalveolar carcinoma-derived alveolar epithelial A549 cells.
2009-02-01

Given the role of phosphoinositide-specific phospholipase C (PLC) isozymes in the control of cell growth and differentiation we were prompted to analyze the expression of some of these PLC in human bronchoalveolar carcinoma-derived alveolar epithelial A549 cells. The effects of several ...

PubMed

7
Carrageenan inhibits granzyme A-induced detachment of and interleukin-8 release from alveolar epithelial A549 cells
2008-11-06

Granzyme A (GrA) is a lymphocyte serine protease that is believed to enter virus-infected cells and growing tumors and induce apoptosis. We found recently that recombinant rat GrA (rGrA) promotes detachment of and interleukin (IL)-8 release from alveolar epithelial A549 cells and suggested that ...

PubMed Central

8
pone.0015750 1.. - Life Sciences Data Archive - NASA

derived from studies that utilized non-polarized monolayer cell ...... SPI-1 Salmonella mutant not only infected the tissues of the small ..... (2005) A549 lung epithelial cells grown as three-dimensional aggregates: .... derivative of another colon adenocarcinoma ...

NASA Website

9
Cytotoxic and genotoxic impact of TiO2 nanoparticles on A549 cells.
2011-02-01

Titania nanoparticles are produced by tons, and included in commercial products, raising concerns about their potential impact on human health. This study relates their cytotoxic and genotoxic impact on a cell line representative of human lung, namely A549 alveolar epithelial cells. ...

PubMed

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