Sample records for aarne luud kalle

  1. Shaping Strategic Defense: The Air Force Nuclear Mission

    DTIC Science & Technology

    2009-01-01

    Strike Command. Washington DC: Department of the Air Force. Kall , Rob. June 20, 2008. “Pentagon: Over 1000 Nuclear Weapons Parts Missing?” http...www.huffingtonpost.com/rob- kall /pentagon-over-1000-nuclea_b_108225.html (accessed December 16, 2008). Rolfsen, B. November 6, 2007. http...16, 2008). 6 Schlesinger. 7 Kall , Rob. June 20, 2008. “Pentagon: Over 1000 Nuclear Weapons Parts Missing?” http://www.huffingtonpost.com/rob- kall

  2. The Tactical Center of Gravity: How Useful is the Concept?

    DTIC Science & Technology

    1990-01-06

    through the Huertgen Forest, across the Kall River, capture the town of Kommerscheidt, and then capture Schmidt. The regiment also was required to protect...south through the woods, cross country to the Kall River, to take Kommerscheidt. The 3rd Battalion was to follow the 1st Battalion and take Schmidt on...desperate struggle. The lead battalions were destroyed piecemeal by the Germans in Kommerscheidt and Schmidt and along the Kall Trail. Poor

  3. Quantitative Infrared Spectroscopic Measurements of Boron Fluorides.

    DTIC Science & Technology

    1980-08-01

    F49620-77-C-0075 Gozewski, S. Kallelis , J.C. Wormhoudt, L.M. Pete rson* I PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT...S.Aernstein. Joel A.Ailverl Wite d- Brown onrad 1. Gozewski, Spiros Kallelis , Joda C. Wormhoudt / t "and Lauren M. Peterson* Center for Chemical and...Joel A. Silver, Mark S. Zahniser, Charles E. Kolb, Robert G. Brown, Conrad M. Gozewski, Spiros Kallelis , and Joda C. WormhoudtI I ABSTRACT A high

  4. A Battalion Staff Prepared for War: The Key to Combined Arms Success on the Modern Tactical Battlefield,

    DTIC Science & Technology

    1988-03-10

    comoat sunort Droblems put the 3d Battalion in a Drecarious Dosition On 4 November. First, the Kall River trail, the major route from the division to...was to maintain one- way traffic through to the Kall River bridge while Company A did the same from the bridge to Schmidt. C Company, in reserve...supply weasels from the 3d Battalion crossed the Kall . (52) Meanwhile, in Schmidt the 3d Battalion prepared to defend. * The battalion had no combined arms

  5. Engineered Resilient Systems: Knowledge Capture and Transfer

    DTIC Science & Technology

    2014-08-29

    development, but the work has not progressed significantly. 71 Peter Kall and Stein W. Wallace, Stochastic Programming, John Wiley & Sons, Chichester, 1994...John Wiley and Sons: Hoboken, 2008. Peter Kall and Stein W. Wallace, Stochastic Programming, John Wiley & Sons, Chichester, 1994. Rhodes, D.H., Lamb

  6. Investigation into the Distribution of Ballast Water Tracers in Coastal Waters

    DTIC Science & Technology

    2009-11-01

    terrestrial and marine vegetation ( Kalle , 1966; Sieberth, 1969; Stabenau et al., 2004), microbial productivity in the water column (Nelson et al...London. Kalle , K., 1966. The problem of the Gelbstoffe in the sea. Oceanogr. Mar. Biol. Ann. Review, 4: 91-104. Lackowicz, J., 1999. Principles of

  7. Using Generalized Annotated Programs to Solve Social Network Diffusion Optimization Problems

    DTIC Science & Technology

    2013-01-01

    as follows: —Let kall be the k value for the SNDOP-ALL query and for each SNDOP query i, let ki be the k for that query. For each query i, set ki... kall − 1. —Number each element of vi ∈ V such that gI(vi) and V C(vi) are true. For the ith SNDOP query, let vi be the corresponding element of V —Let...vertices of S. PROOF. We set up |V | SNDOP-queries as follows: —Let kall be the k value for the SNDOP-ALL query and and for each SNDOP-query i, let ki be

  8. Quantitative and Qualitative Prediction of Light Absorption by Colored Dissolved Organic Matter in the Coastal Zone

    DTIC Science & Technology

    2008-01-01

    North Sea region CDOM has been shown to behave quasi conservatively and be a useful tracer of water mass mixing ( Kalle 1949; Højerslev 1988...Project started in 2005 and ended in 2007, with a budget of 1.4 million DKK (approx. US$230,000). REFERENCES Kalle K. 1949. Fluoreszenz und

  9. Towards DNA-Based Programmable Matter

    DTIC Science & Technology

    2012-02-28

    optics. Nature 2003, 424, 824–830. (2) Xu, H. X.; Bjerneld, E. J.; Kall , M.; Borjesson, L. Spectroscopy of single hemoglobin molecules by surface...Brenner, M. P.; Manoharan, V. N. The Free-energy Landscape of Clusters of Attractive Hard Spheres. Science 2010, 327, 560–563. (35) Xu, H. X.; Kall , M

  10. Reduced-Order Observer Model for Antiaircraft Artillery (AAA) Tracker Response

    DTIC Science & Technology

    1979-08-01

    a22 -ka1 2) z + (a22 - ka1 2) ky + (a21 - kall ) y + (b2 - kb) uc (10) Next, the actual output of this model is expressed as the sum of the output u...a22x2 + b2u + f2eT = (a2 2 - kal2) z + (a2 2 - ka12) ky + (a21 - kall ) y + (b2 - kb l ) uc u=u +vC [Ti Y2] [y] By introducing new variables: X3 = x2...x3 [(a22- ka2)k + (a2- kall ) - (b2- kb) (YI + kY2) Y + [a22 - ka12 - (b2 - kbl) Y2] X3 + (b2 -kbl) y2 e + (2 - kbI) v + (f2 - kfl) 0 T e = (a22- ka12

  11. Analysis of Fleet Reports of Bioluminescence in the Indian Ocean

    DTIC Science & Technology

    1981-12-14

    Kalle [ 20,21], who theorized that they were caused by seismic disturbances. According to his theory, such disturbances would produce wheels in...Whether this phenomenon is the same as that described by Kalle is uncertain. The description of the phosphorescent wheel, however, was truly classic. The...Luciferin in Some Shallow-Water FisheF Comp. Biochem. Physiol. 40A:163-179, 1971 . 14. P. J. Herring, "Observations of Bioluminescence at Sea," Mar. Obs. 46

  12. Second Analysis of Fleet Reports of Bioluminescence in the Indian Ocean.

    DTIC Science & Technology

    1983-12-15

    9. K . Kalle , "Die ritselhafte und unheimliche Naturerscheinung des ’explodierenden’ und des ’rotierenden’ Meeresleuchtens-eine Folge lokaler Seebeben...34 Deutsche Hydrog. Zets. 13, 49-77 (1960). 10. K . Kalle , "Wheels of Light," Sea Frontiers 15(2), 116-122 (1969). f a ** . . . . . . . ~ ... - VI. ISM ...Special \\roti ’ I , ~ ~ ~ ~ ~ ~ %WT- 2.7%,: 7% l. * , ,- .. I.’ - 1 . ’%- , . • ’- 17-* -’ k - - ’. -’ SECOND ANALYSIS OF FLEET REPORTS OF

  13. Marine Particulate Absorption Techniques and Applications in the Study of Inherent and Apparent Optical Properties of the Ocean

    DTIC Science & Technology

    1992-01-01

    Meteortpl.. 24. 193-205. 1985. Bricaud. . . Morel, and L. Prieur. Absorption by dissolved Kalle . K .. What do we know about the ’Glso’. nor.10...Oceanogr.. 26. 43-53. 1991. Kalle . K .. The problem of Gelbstoff in the sea. Oceanogr. Mar. Bricaud..5A. Morel, and L. Prieur. Optical efficiency factors of...with report. Carder, K . L, S. K . Hawes, K . A. Baker, R. C. Smith, R. G. Steward, B. G. Mitchell. 1991. Reflectance model for quantifying chlorophyll a

  14. Potential of Remote Sensing in the Corps of Engineers Dredging Program.

    DTIC Science & Technology

    1985-11-01

    remotely sensed sultispectral data. Earth Resources Survey Symposium June 9-12, Houston. Texas. Lyndon B. Johnson Space Center, pp. 2087-2098. Kalle , K ...a" -- , :0 0 4 n - 0 00 0 𔃾A 14. U ,U a4 t4 f"’ 4- t4- -- cf 0 0-4 z so a 0 . 4," . +" ’," - AC8" N N- ,, . -o - o 0 0 - 4.4 o o 0’, K . 0...signal. Several studies have shown that many substances can be identified by their optical properties. Using cruise data, Kalle (1966) was one of the

  15. Urinary coagulation-fibrinolysis, kallirein-kinin systems and kininase in cases of preclampsia.

    PubMed

    Mutoh, S; Kobayashi, M; Hirata, J; Itoh, N; Maki, M; Komatsu, Y; Yoshida, A; Sasa, H; Kuroda, K; Kikuchi, Y

    1992-01-01

    Urinary kallikrein and kallikrein activity significantly decreased in cases of preeclampsia (u-kall./CRE.index 42.39 +/- 9.66 ng/mg, u-kall. act./CRE.index 0.26 +/- 0.06 ng/min/mg), and urinary kininase II and kininase activity significantly increased (u-kininase/CRE.index 10.91 +/- 1.26 x 10(-3) IU/min/mg, u-kininase act./CRE.index 506.37 +/- 178.45 pg/min/mg) when compared with those of normal gravidas from 28 weeks to 42 weeks of gestation (u-kall./CRE.index 189.31 +/- 14.17 ng/mg, u-kall. act./CRE index 1.08 +/- 0.10 ng/min/mg, u-kininase/CRE.index 6.24 +/- 0.31 x 10(-3) IU/min/mg, u-kininase act./CRE.index 15.64 +/- 0.10 pg/min/mg). Urinary FPA, B beta 5-42, alpha 2-PI, and alpha 2PI-plasmin-complex (PIC) significantly increased in preeclampsia (u-FPA/CRE.index 23.59 +/- 8.47 ng/mg, u-B beta/CRE.index 105.26 +/- 29.30 ng/mg, u-alpha 2PI/CRE.index 121.53 +/- 43.57 ng/mg, u-PIC/CRE index 278.39 +/- 60.50 ng/mg) when compared with those of normal control group (u-FPA/CRE.index 0.92 +/- 0.04 ng/mg, u-B beta/CRE.index 12.15 +/- 0.44 ng/mg, u-alpha 2PI/CRE.index 4.18 +/- 0.33 ng/mg, u-PIC/CRE.index 5.98 +/- 1.15 ng/mg). Urinary urokinase markedly increased and urinary D-dimer was detected in severe cases of preeclampsia (u-UK/CRE.index 58.20 +/- 43.69 ng/mg, u-D-dimer 54.76 +/- 9.89 ng/ml) when compared with those of normal control group. These findings suggest that deficiency in urinary kinin excretion may induce hypertension in addition to the changes of urinary coagulation-fibrinolysis system that represents the occurrence of either the endothelial cell injury in the glomerulus or the renal tulbular damage in mild cases of preeclampsia, eventually resulting in the intra-renal vascular coagulation.

  16. Examination of Cement Pastes Hydrated Phases, and Synthetic Products by X-Ray Diffraction

    DTIC Science & Technology

    1972-04-01

    International Union o, Crystallography Commission on Crystallo- graphic Data, Powder Data, Journal of Applied Crystallography, Vol 4, pp 81-86, 1971 . 21...Papes, Research Series 1, Building Research Station, 1962. 25. l,, Dosch, Rbntgen-Ceinstrukturuntersuchu , luftemp’indlicher pulverprlparate, Zement- Kall

  17. When the Japanese Bombed the Huertgen Forest: How the Army’s Investigation of Pearl Harbor Influenced the Outcome of the Huertgen Forest, Major General Leonard T. Gerow and His Command of V Corps from 1943-1945

    DTIC Science & Technology

    2011-05-19

    only a narrow supply line that passed along a narrow one-lane path called the Kall Trail.13 The Germans mounted fierce counter-attacks well supported...Bradley. New York: Ballantine Books, 1971 . ________. West Wall: The Battle For Hitler’s Siegfried Line. Conshohocken, PA.: Da Capo Press, 2000

  18. A Critical Comparison of Some Methods for Interpolation of Scattered Data

    DTIC Science & Technology

    1979-12-01

    because faster evaluation of the local interpolants is possible. KAll things considered, the method of choice here seems to be the Modified Quadratic...topography and other irregular surfaces," J. of Geophysical Research 76 ( 1971 ) 1905-1915I’ [23) HARDY, Rolland L. - "Analytical topographic surfaces by

  19. Conducting Studies of Transfer of Learning: A Practical Guide

    DTIC Science & Technology

    1982-01-01

    X) = percent transfer (If learning C where: Kall aicrage of grades assigned to experimental :.ttmdents for p~erformlanlce in the aircraft. an average...effectiveness. Human Factors. 1971 . 13(6). 561-567. Roscoe, S.N. A little more on incremental transfer effectiveness. Human Factors. 1972, 14(4), 363-364

  20. Sublinear Upper Bounds for Stochastic Programs with Recourse. Revision.

    DTIC Science & Technology

    1987-06-01

    approximation procedures for (1.1) generally rely on discretizations of E (Huang, Ziemba , and Ben-Tal (1977), Kall and Stoyan (1982), Birge and Wets...Wright, Practical optimization (Academic Press, London and New York,1981). C.C. Huang, W. Ziemba , and A. Ben-Tal, "Bounds on the expectation of a con

  1. Numerical and Experimental Investigation of Multiple Shock Wave/Turbulent Boundary Layer Interactions in a Rectangular Duct

    DTIC Science & Technology

    1988-01-06

    the bottom % kall followin,, the interaction. At 6Wuh = 0.35 the shock train would not stay attached to a single wall long enough for the surface...Interaction of a Shock Wave with a Laminar Boundary Layer," Lecture Notes in Physics, Vol. 8, Springer-Verlag, 1971 , pp. 151-163. 51 MacCormack, R. W

  2. The Transient Excitation and Oscillation Testing Technique Applied to a Captive Model.

    DTIC Science & Technology

    1981-06-01

    8217Kall io I 9. PERFORMING ORGANIZATION NAME AND ADDRESS PROGRAM ELEMENT. PROJECT, TASK David W. Tayl.or Naval Ship Research and -OW UNIT NUMBERS...corrective tare terms (C’. 11 C35’ C 53 and C 55) used in calculating the nondimensional oscillat ion coff ticient s. Figures 7--14 contain comparisons of

  3. Issues Related to Recruitment of Enlisted Personnel for the Reserve Components. Volume 3. Methods Volume. Wave III.

    DTIC Science & Technology

    1981-03-01

    OO3 b’ As.nciates for Rusearch in Behavior, 1971 -- 1978. O -3- TABLE 1-1. PRIOR SERVICE SUBSAINPLE SIZES PRIOF SERVICE AMEFS =NAMES# SUBSAYPLE...BLK.266 ST.36 SRVC, kALL DATE TIME INTERV RESULT GCNZALEZNELSOh ANINIC, I- r 111-17 167 ST 2 JAMAICA NV 11433 2 / __ 0 3 4 NA BY CB c B -I

  4. Installation Restoration Program. Phase II - Confirmation/Quantification. Stage 1 for American Lake Garden Tract, Washington.

    DTIC Science & Technology

    1985-12-20

    Kalles . 1976. Evaporation rates of methylene chloride, chloroform, 1,1,1-trichloroethane, trichloroethylene, tetrachoroethylene, and other chlorinated...State University (1969) M.S., Geology, University of Washington ( 1971 ) . . Ph.D., University of Washington (1979) " EXPERIENCE 1984 to Date Senior...ducted environmental assessments for Pacific Northwest construc- tion projects. L- 1971 Project Geologist, SEREM of Alaska (BRGM-France). Responsibil

  5. Coherent Plasmon-Exciton Coupling in Silver Platelet-J-aggregate Nanocomposites

    DTIC Science & Technology

    2015-02-27

    2011, 11, 1556−1560. (12) Zengin, G.; Johansson, G.; Johansson, P.; Antosiewics, T. J.; Kall , M.; Shegai, T. Sci. Rep. 2013, 3 (3074), 1−8. (13...Mater. 2005, 17, 412−415. (21) Davydov, A. S. Theory of Molecular Excitons; Plenum Press: New York, 1971 . (22) Van Burgel, M.; Wiersma, D. A.; Duppen, K

  6. Forecast of Future Ohio River Basin, Waterway Traffic Based on Shippers Surveys.

    DTIC Science & Technology

    1979-09-01

    pattern. Analytic Tool: SPSS KAll of the editing, generation of tables, graphing, and other com- putational activities were carried out through the use...00O’s) 1976-1g90 Group 1971 1990 (%) 1976 190 (9) Coal & Coke 0 0 0 1,617 3,231 +100 Petroleum Fuels 705 779 +10 509 509 +0 Aggregates 0 0 0 450 688

  7. Inventory of Archaeological and Historical Resources Lava Flow Control Study, Hilo, Hawaii,

    DTIC Science & Technology

    1979-05-01

    amale- p 11111 S.PIaN. Sitea card; hial. 1971 :2 aa. INVENTRh Y OF AIIAj4AOLGICAL AND HISIORICAL ESItIMCES Sit umber Site Ded𔃻ption e Period Coed...liaison. 1932:294 SO-a-Al-ST Kalled , paved 4 PPI.Site Card; NHudson, 1932:29S.2W6 terraced platorm bo-Li-AI. 55$ Legendary crevite, Esrsaa% 1903:Is

  8. Wartime Requirements for Ammunition Materiel and Personnel (WARRAMP). Volume II. Materiel Postprocessor Program Maintenance Manual

    DTIC Science & Technology

    1981-08-01

    00 .1 00 -0 71: 3.1%2 7.460 . 30 1.0 0 .950 AS .1491 .? 0o -T 00 .8 72: G3: 70; ARTY KALLS FATORS B0 050BR CAS T ERO 7?211 .000 1.70 .000 I.000 .1500...Administrative and Logistic Support (FASTALS), Documentation, Research Analysis Corporation, RAC-R-86, dated May 1971 . F. Army Automation, Documentation Standards

  9. STAMMER2 Production System for Tactical Situation Assessment. Volume 2. Code.

    DTIC Science & Technology

    1979-10-01

    1961 (WITHINR * [NLAMBDA L (*NOBIND ൖ-Nov-78 19:25") (NCONC WITHINRFNS L) (MAKEFILE (QUOTE WITHINR.LSP]) [ 1971 (CROSSPATHS [LAMBDA (Si S2 TI T2)V...176 46. 1 I 1 FKACS 47. 1 I FKSYM (221 48. 1 FKIDPB 49. I M KALL (9) 50. 1 DSPTTY FKCALL (9) 51. I 1 FKJSYS (3) 52. 1 1 1 DSPTTYSTR DECSAMEDIGITS {bl

  10. The accuracies of DNA-based estimates of genetic merit derived from Angus or multibreed beef cattle training populations.

    PubMed

    Weber, K L; Drake, D J; Taylor, J F; Garrick, D J; Kuehn, L A; Thallman, R M; Schnabel, R D; Snelling, W M; Pollak, E J; Van Eenennaam, A L

    2012-12-01

    Several organizations have developed prediction models for molecular breeding values (MBV) for quantitative growth and carcass traits in beef cattle using Bovine SNP50 genotypes and phenotypic or EBV data. Molecular breeding values for Angus cattle have been developed by IGENITY, Pfizer Animal Genetics, and a collaboration between researchers from Iowa State University and the University of Missouri-Columbia (ISU/UMC). The U.S. Meat Animal Research Center (USMARC; Clay Center, NE) has also developed MBV for 16 cattle breeds using 2 multibreed populations, the Germplasm Evaluation (GPE) Program and the 2,000 Bull Project (2K(ALL)), and 2 single breed subpopulations of the 2,000 Bull Project, Angus (2K(AN)) and Hereford (2K(HH)). In this study, these MBV were assessed relative to commercial ranch EBV estimated from the progeny phenotypes of Angus bulls naturally mated in multisire breeding pastures to commercial cows: 121 for USMARC MBV, 99 for ISU/UMC MBV, and 29 for IGENITY and Pfizer MBV (selected based on number of progeny carcass records). Five traits were analyzed: weaning weight (WW), HCW, marbling score (MS), rib-eye muscle area (RE), and, for IGENITY and Pfizer only, feedlot ADG. The average accuracies of MBV across traits were 0.38 ± 0.05 for IGENITY, 0.61 ± 0.12 for Pfizer, 0.46 ± 0.12 for ISU/UMC, 0.16 ± 0.04 for GPE, 0.26 ± 0.05 for 2K(ALL), 0.24 ± 0.04 for 2K(AN), and 0.02 ± 0.12 for 2K(HH). Angus-based MBV (IGENITY, Pfizer, ISU/UMC, and 2K(AN)) explained larger proportions of genetic variance in this population than GPE, 2K(ALL), or 2K(HH) MBV for the same traits. In this data set, IGENITY, Pfizer, and ISU/UMC MBV were predictive of realized performance of progeny, and incorporation of that information into national genetic evaluations would be expected to improve EPD accuracy, particularly for young animals.

  11. Propagation of Sound Through the Atmosphere: Effects of Ground Cover

    DTIC Science & Technology

    1978-06-19

    Over Simulated Ground Cover", J. Acoust. Soc. Am. 49, 1069-1075 ( 1971 ). 8 J. . . Piercy, T. F. W. Embleton, and L. C. Sutherland, "A Review of Noise...FlPST., AM KALL C AND SUBMOUTINL NAIAE *𔃺’t.ATfl"v hISTTAD 0t "COPPIS?". C PANG4N IS Ali tUIT 01* IAANG4Kp [XCLUSVIfo UT NTt.14VENINC, Fj)ITSq C RANG

  12. Archaeological Investigations at Site 45-OK-11, Chief Joseph Dam Project, Washington.

    DTIC Science & Technology

    1984-01-01

    Russian thistle (_Iol]L kALL ), and thistle ( r_ _ium spp.) among others. Scattered sagebrush and rabbitbrush . (Chrysothamnus nauseosus), and a dense...described in detail selectively. All artifact analyses take the form of paradigmatic classifications as defined by Dunnell ( 1971 , 1979). In this system...with certain methods of production and particular steps in the reductive sequence (e.g., Crabtree 1972, 1976a,b; Flenniken and Garrison 1975; Muto 1971

  13. Chance Constrained Programming Methods in Probabilistic Programming.

    DTIC Science & Technology

    1982-03-01

    Financial and Quantitative Analysis 2, 1967. Also reproduced in R. F. Byrne et. al., eds.5tudies in Budgeting (Amsterdam: North Holland, 1971 ). [3...Rules for the E-Model of Chance-Constrained Programming," Management Science, 17, 1971 . [23] Garstka, S. J. "The Economic Equivalence of Several...Iowa City: The University of Iowa College of Business Administration, 1981). -3- (29] Kall , P. and A. Prekopa, eds, Recent Results in Stochastic

  14. Cardiorespiratory Changes During Microwave-Induced Lethal Heat Stress and Beta-adrenergic Blockade

    DTIC Science & Technology

    1994-01-01

    J. A. Taylor, J. K . Kalls , J. Nit- verse these responses. Fundam. Appl. Toxicol. 10- 506-516, 1988. tolo, R. W. Hicks, T. G. Lohmnan, and J. H...propanolol groups were significantly lower than in saline controls. Respiratory rate was significantly elevated during most of the exposure period in...lar and respiratory changes) during lethal exposures. Al- propranolol groups were significantly lower than in saline con- though the pathophysiology

  15. Remotely Piloted Vehicles Design Option Decision Trees

    DTIC Science & Technology

    1975-06-01

    of Lrade-off options available before inception of hardware design (Askren and Korkan, 1971 ; Askren, Korkan, and Watts, 1973). The purpose of the study...bouso~ENGIN LAVEIVESi SLIPSTRCA LAS? SOURCE HIGH LIFT DEVICE$ FLAPS SIGESO GRACES~~~ -AULILESOrCTER kALL T RCD TEMPERATUR EQUIPNENT COS,.UV...Method for Relating Human Resources Data to Design Parameters, AFHRL-TR-71-52, December 1971 . Barnes, B.P., Baker, L.A., and McIntosh, B.E., The

  16. Development and Evaluation of a Casualty Evacuation Model for a European Conflict.

    DTIC Science & Technology

    1987-08-18

    W Applications and Computations," lIE Transactions, 16, 2, 127-134 "- ( 1984 ).-,’’ ,., 3. Ali, A. I., Helgason, R. V., Kennington, J. L., and kall ...Part II," Mathematical Programming, 1, 6-25 ( 1971 ). 38. Held, M., Wolfe, P., and Crowder, H., "Validation of Subgradient Optimization", Mathematical...California, Los Angeles, CA, ( 1971 ). Si 66. Swoveland, C., "A Two-Stage Decomposition Algorithm for a Generalized Muticommodity Flow Problem," INFOR

  17. Man-Machine Interface (MMI) Requirements Definition and Design Guidelines

    DTIC Science & Technology

    1981-02-01

    be provided to interrogate the user to resolve any input ambiguities resulting from hardware limitations; see Smith and Goodwin, 1971 . Reference...Smith, S. L. and Goodwin, N. C’. Alphabetic data v entry via the Touch-Tone pad: A comment. Human Factors, 1971 , 13(2), 189-190. 41 All~ 1.0 General (con...software designer. Reference: Miller, R. B. Response time in man-computer conversational transactions. In Proceedings of the AFIPS kall Joint Computer

  18. Radio Wave Propagation: A Handbook of Practical Techniques for Computing Basic Transmission Loss and Field Strength

    DTIC Science & Technology

    1982-09-01

    MARK A. WEISSBEGU KALLE R. XONTSON Project Msnaqer, IUTRZ Assistant Director Contractor Operations Approved by CRARLES L. FLYNN, 001, us A. M. MESSE...34 BSTJ, 1946. 2-4priis, H.T., "Introduction to Radio and Antennas," IEEE Spectrum, April, 1971 . RADIO WAVE PROPAGATION: A HANDBOOK OF PRACTICAL...Propagation Tests, TR-0177-71.01, Gautney & Jones Communications, Inc., Falls Church, VA, June 1971 . 3 -7 Comparison of Predicted VLF/LF Signal

  19. Seamless Integration of Detection and Therapy for Breast Cancer using Targeted Engineered Nanoparticles

    DTIC Science & Technology

    2006-06-01

    Rangel, R.; Sun, Y.; Zaoui, K.; Schmidt, M.; Kalle, C. v.; Weitzman, M. D.; Gelovani, J. G.; Pasqualini , R.; Arap, W., A Hybrid Vector for Ligand...A.; Holbeck, S. L.; Sausville, E. A.; Arap, 7 W.; Pasqualini , R., Ligand-Directed Surface Profiling of Human Cancer Cells with Combinatorial...Ozawa, M. G.; Snyder, E. Y.; Sidman, R. L.; Miller, J. H.; Arap, W.; Pasqualini , R., Networks of gold nanoparticles and bacteriophage as biological

  20. High Mobility Driver Performance Analysis

    DTIC Science & Technology

    1981-06-01

    Adjusted Residuals 25 Table 13. Trials kAll Trials Including Civilian Drivers) During which Critical Incidents Occurred (Or Did Not Occur) 26 Table 14...0.05 (Winer, 1971 )3. At, the close of training an error score had been selected from amons alternative formulations as reasonably representative of...USNPA, Aug 1968. Winer, B. J. Statistical Principles in Experimental Design. Second (2d) edition. McGraw-Hill, New York, 1971 . 35 IN hi a. I i d A-14

  1. JPRS Report West Europe

    DTIC Science & Technology

    1988-08-12

    that first graders are the nicest, like all in one big family. Well-behaved and obedient. Maybe Matti teases Maija a little bit and Pekka pushes Kalle ...France as early as 1971 . The system designed for Finland is an all-weather ver- sion and it was originally intended to specifically destroy low-flying...ISTAT study covers principally the three years of 1984-86, but also examines the evolution of crime in Italy since 1971 . And this could not have

  2. Selectivity of Odorant Receptors in Insects

    DTIC Science & Technology

    2012-07-13

    Regnier, 1971 ), which is equivalent to an endogenous agonist, may be expanded to include the following criteria: 1. Semiochemicals are natural...journal.pone.0030304 Law, J. H., and Regnier, F. E. ( 1971 ). Pheromones. Annu. Rev. Biochem. 40, 533–548. Lu, T., Qiu, Y. T., Wang, G., Kwon, J. Y...malaria vector mosquito Anopheles gambiae. Curr. Biol. 17, 1533–1544. Lundin, C., Kall , L., Kreher, S. A., Kapp, K., Sonnhammer, E. L., Carlson, J. R

  3. Survivability Study of a FLIR Equipped Fighter on a Night Penetration of a Soviet Army.

    DTIC Science & Technology

    1981-03-01

    4L TATL KALL . .5500E.1 .:02SE+I .55015E+00 .I 1E+II .II#E+#Z it 102 ’I" ADnend i x ( RANG;ES Comni r er 1’rn rqm Thft; nrnpram rnmniitpq the r ximum...VEL SIGMA .584 1 .514 .097 .756 1971 = ALT SIGMA 142.675 2 71.337 13.724 ,W91 1080= 1690= 3-WAY INTERACTIONS 52.133 16 3.258 .627 .868 1I#= NET RATE VEL

  4. Revegetation Study of Adobe Dam, Phoenix, Arizona. Task 2. Revision.

    DTIC Science & Technology

    1983-08-01

    revegetation. *~ ~ A DDoa or?, I47 MDTOOOV 65IS OBSOLETE SECURITY CLASSIFICATION OF THIS PAGE (Wh"e Ders, Enreedl k ’, ... . .- r77. -. r - -V...addition to sodic soils, five sites along the wash were discovered to have salinity problems, with electrical conductivity in excess of 4. mmhos/cm. This...established at Indian Bend Wash.This species, along with Salla kalL (Tumbleweed) made upthe majority of the vegetation in 1979. Since 1979, as thedata in

  5. A Synopsis of the Chemical/Physical Properties of Seawater

    DTIC Science & Technology

    1988-01-01

    N20 -59.5965 97.3066 24.1406 -0.058420 0.033193 -0.0051313 4 1Weiss (1970), 2Weiss ( 1971 ), 3 Wiesenburg and Guinasso (1979), 4 Weiss and Price...20 30 40 50 60 70 80 90100 Temperature ( ° C) FIG. 5. Velocity of light in pure water and seawater as a function of temperature, from Kalle (1942...of Sheet Pile Structures, from U.S. Navy Design Manual ( 1971 ). Types of structure Factors affecting deterioration Harbor bulkheads Beach bulkheads

  6. Solution Methods for Stochastic Dynamic Linear Programs.

    DTIC Science & Technology

    1980-12-01

    16, No. 11, pp. 652-675, July 1970. [28] Glassey, C.R., "Dynamic linear programs for production scheduling", OR 19, pp. 45-56. 1971 . 129 Glassey, C.R...Huang, C.C., I. Vertinsky, W.T. Ziemba, ’Sharp bounds on the value of perfect information", OR 25, pp. 128-139, 1977. [37 Kall , P., ’Computational... 1971 . [701 Ziemba, W.T., *Computational algorithms for convex stochastic programs with simple recourse", OR 8, pp. 414-431, 1970. 131 UNCLASSI FIED

  7. The Combined Arm Battalion and Airland Battle,

    DTIC Science & Technology

    1986-12-01

    through Vossenach, across the Kall River, and on to Kommerscheidt and Schmidt. Although this trail was the major route for reinforcements and resupply...the division. The use of armor in support of the operation wa3 al-ii oo. Tanks were unable to traverse the narro)w and steeply ba:iked K .-il River...from the 53rd Armored Infantry Battalion opened up the bridgehead over the Moselle River in the initial movement towards ChateaU- 48 Salins . In this

  8. Vector/Matrix Quantization for Narrow-Bandwidth Digital Speech Compression.

    DTIC Science & Technology

    1982-09-01

    8217o 0 -X -u -vc "oi ’" o 0 00i MN nM I -r -: I I Ir , I C 64 ut c 4c -C ;6 19I *~I C’ I I I 1 Kall 9 I I V4 S.0 M r4) ** al Iw* 0 0 10* 0 f 65 signal...Prediction of the Speech Wave, JASA Vol. 50, pp. 637-655, April 1971 . - 2. I. Itakura and S. Saito, Analysis Synthesis Telephony Based Upon the Maximum

  9. Wavevector-Frequency Analysis with Applications to Acoustics

    DTIC Science & Technology

    1994-01-01

    Turbulent Boundary Layer Pressure Measured by Microphone Arrays," Journal of the Acoustical Society of America, vol. 49, no. 3, March 1971 , pp. 862-877. 1...ARplications of Green’s FuntionsinScie,.-and Enginlering, Prentice-Hall, Inc., Englewood Hills, NJ, 1971 . 9. 3. Ffowcs-Williams et al., Modern Methods for...variables of a random process are kalled Joint w.merit ,. The m,n-th joint moment of the random variables, v and w, iz flefined by E ,N 1 f (aB) do d- where

  10. Regenerative Simulation of Response Times in Networks of Queues.

    DTIC Science & Technology

    1979-11-01

    i jobs at center 1. Nov consider the network of queues in Figure 2.2, formulated (Lewis and Shedler ( 1971 )) as a model of system overhead in...7.2 leading to point estimates and confidence intervals for the quantity r(f) are that the pairs of random variables {( V(fHk) : kall (9.2.3) are...189 Next we show that P’=P. Since P ’m"CIP for all i, we can use the Skorohod representation theorem (see Skorohod (1956) or Billingsley ( 1971 )) to

  11. NPS-PASCAL. A Microcomputer-based Implementation of the PASCAL Programming Language.

    DTIC Science & Technology

    1980-03-01

    rCL (N BASED PRINTNAME)(1) BTEV; CALL LI ’ ITS (I: =N (0)4-7); CALL 7NTEmRtLINKS; 12%- CALL ST A DrRT ( ); PY’EPTR(e)= FOR" kALL S7ET.DDRPTR(!K...kAccI, 1971 . 7* Flynn.,C P. and Moranville, .S., kL-;T_-v0 T -Dl1e7-itaticn Cf A Fi-I 1-vel 3o tt~ lanr’uape F-cr A M’icroccssor-bs- C~’-:uter Sy st

  12. A Dermatologist's Ammunition in the War Against Smoking: A Photoaging App.

    PubMed

    Brinker, Titus Josef; Enk, Alexander; Gatzka, Martina; Nakamura, Yasuhiro; Sondermann, Wiebke; Omlor, Albert Joachim; Petri, Maximilian Philip; Karoglan, Ante; Seeger, Werner; Klode, Joachim; von Kalle, Christof; Schadendorf, Dirk

    2017-09-21

    This viewpoint reviews the perspectives for dermatology as a specialty to go beyond the substantial impact of smoking on skin disease and leverage the impact of skin changes on a person's self-concept and behavior in the design of effective interventions for smoking prevention and cessation. ©Titus Josef Brinker, Alexander Enk, Martina Gatzka, Yasuhiro Nakamura, Wiebke Sondermann, Albert Joachim Omlor, Maximilian Philip Petri, Ante Karoglan, Werner Seeger, Joachim Klode, Christof von Kalle, Dirk Schadendorf. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.09.2017.

  13. Uranium Oxide Gaseous Ion and Neutral Infrared Spectroscopy

    DTIC Science & Technology

    1983-12-31

    Kallelis , and q technical advice received from Drs. Charles E. Kolb, Kurt Annen, Alan Stanton, * and Mark Zahniser of Aerodyne and G. Sargent Janes of Avco...Chem. 75, ( 1971 ) 2283. - S6. S. Abramowitz and N. Acquista, J. Phys. Chem. 76, (1972) 647. 7. H.J. Leary, Jr., T.A. Rooney, E.D. Cater, and ll.B...Friedrich, High Temp. Scd. 3, ( 1971 ) 433. 8. D.H.W. Carstens, D.M. Gruen, and J.F. Kozlowski, High Temp. Sed. 4, 436 (1972). 9. a) M.J. Krauss and W.J

  14. Pleiotrophin as a Growth Factor and Therapeutic Target in Breast Cancer

    DTIC Science & Technology

    1997-10-01

    novel phospholipase A2 related gene. Nucl Acid Res 21:135-143. 11. Gattoni-Celli, S., K . Kirsch, S. Kalled , and K . J. Isselbacher. 1986. Expression...clone (G11-F7) is enlarged. Genomic Southern blot probes (a,b,c) and restriction sites are shown (B=BamHI, H=HindIII, Sc=ScaI, K =KpnI). 10WJ 3fr 4&V...otherwise in 25 mM Tris pH8.3/200 mM glycine/20% methanol. The membrane was blocked in PBS (phospate-buffered saline )/0.1% Tween 20/5% powdered milk and

  15. Oxidation of Thiodiglycol (2,2’-Thiobis-ethanol) by Alcohol Dehydrogenase: Comparison of Human Isoenzymes

    DTIC Science & Technology

    2000-01-01

    Ethanol by ADH Isozymes0 Isozyme TDC Ethanol Class K „ b *cat/-Nn K , *cat Kall ^m I act 8.6 (7.9 ± 1.2)e 63 7 4.2 54 13 PiPi 3.5 (4.2 ± 0.4) 34 8 0.05...the appropriate concentration of substrate in 0.85% saline was added. The reaction was followed by measuring the change in absorbance at 340 nm...ß2ß2 from Kedishvili et al. [271. * K „ values obtained from Lineweaver-Burk plots (Figure 1). ’Values in parentheses are X„s ± S.E. calculated from

  16. Numerical Methods for Synoptic Computation of Oceanic Fronts and Water Type Boundaries and their Significance in Applied Oceanography

    DTIC Science & Technology

    1966-06-01

    and L. C. Clarke 1965 Clarke, L. C. and R. J. Renard 1966 Dietrich, G. and K . Kalle 1957 Dietrich, G. 1964 Griffiths, R. C. 1965 Hela...8217s n AppA. 1 (sd LiceanGgrapny« (9) T s c h n 1 ’■■- a i. n Q ’z.e , ■: 10) Ci Bf k e , I..... ^ i-’ •■ (10) i...aevastu , i . ill) J u...only between water masses of different salinity but also between those differing in other properties, such as temperature." The nature of the oceanic

  17. Impact of 1/8 degree to 1/64 degree Resolution on Gulf Stream Model-Data Comparisons in Basin-Scale Subtropical Atlantic Ocean Models

    DTIC Science & Technology

    2000-01-01

    Momentum Fluxes. NOAA Atlas NESDIS 8 vol. 3 US Department of Commerce, NOAA, NESDIS, 413 p. Dietrich, G., Kalle , K ., Krauss, K ., Siedler, G., 1980...depth, hydrodynamic model are given below for layers ks1 . . . n with ks1 for the top layer. In places where k is used to index model interfaces, ks0 is...the surface and ksn is the bottom. EU 1 E U u E V u cosuŽ . Ž . k k k k k q q yV u sinuqaV sin2uŽ . k k Et acosu Ef Eu sqmax 0,yv u qmax 0,v u y max 0

  18. Davis Monthan AFB Tucson, Arizona. Revised Uniform Summary of Surface Weather Observations (RUSSWO)

    DTIC Science & Technology

    1976-07-01

    ATA PRUCCSSING BRANC𔃾 UAF ElA CEILING VERSUS VISIBILITY +-AIR W/ kAll ’ , SIRVICEI/1iC 2JIU9 D, V1S MU 1IMA, AFB AkIZONAUC51UCI) ,)-45peif8-75 DEC 5T+O... 1971 蔵 69j "l 1 .74 681 0 2 2 626 103 -42/;Ol3j 14 - 1120 L -,AN 4--- - -- - 27, 313 ____ ____- --- K -- --±-183 ni n 166 42 mn Wkl I _ 1 1...161 1971 187 5 1 541 53 1 1 .2 . .4 .1 .7 l.3 .4 .7 #. 1 1__6 L 1_0 11 2 58/ 47,*00 0 0 94 *l .2 iol2 5-- 49 .Q .49 . .7 .6 .7 .5 o0 10_

  19. Summary of Meteorological Observations, Surface (SMOS), Midway Island.

    DTIC Science & Technology

    1984-08-01

    8 1.7 415 !I _? .,8 1.3.. 35 1962 9 ’.2 32 l󈧽 9 t.o 27 1965 10 1.2 2 1062 10 1 z1 1*6?2 11 1 - 641 ’ .E 24 1971 12 ’.11 1 !97 12 100 77 19 __9 13 1... 1971 22 1. 4 72 19ev 22 2 0 < 53 1’$6 7_______ 23 *1 . 961 23 1.13 2 ; 1981 24 ". 1’ 5 46P 24 1.-4 42’ 1952 25 ’. 0 36 1i)79 26 l.’b %s 蚝 1 26 𔃻. 6...OBSERVATIONS) j2 7ŕ 74!:WAY !SLA.𔃼 73-R2 MAY SiUUlm iS&AYWI MUl Y IOUAI kALL WEATHEP IP MMW=N ( L.8.1 . SIf, UL S aiim MEAN INTS I13 4.6 7-10 1114 17.21

  20. Patient-Centered Mobile Health Data Management Solution for the German Health Care System (The DataBox Project).

    PubMed

    Brinker, Titus Josef; Rudolph, Stefanie; Richter, Daniela; von Kalle, Christof

    2018-05-11

    This article describes the DataBox project which offers a perspective of a new health data management solution in Germany. DataBox was initially conceptualized as a repository of individual lung cancer patient data (structured and unstructured). The patient is the owner of the data and is able to share his or her data with different stakeholders. Data is transferred, displayed, and stored online, but not archived. In the long run, the project aims at replacing the conventional method of paper- and storage-device-based handling of data for all patients in Germany, leading to better organization and availability of data which reduces duplicate diagnostic procedures, treatment errors, and enables the training as well as usage of artificial intelligence algorithms on large datasets. ©Titus Josef Brinker, Stefanie Rudolph, Daniela Richter, Christof von Kalle. Originally published in JMIR Cancer (http://cancer.jmir.org), 11.05.2018.

  1. Hoechst and Wacker plan joint venture in PVC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Young, I.

    1992-12-02

    Restructuring of Europe's petrochemical industry has taken a further step with the announcement that Hoechst (Frankfurt) and Wacker Chemie (Munich) are planning a joint venture in polyvinyl chloride (PVC). The venture would include production, R D, sales and marketing, plus both companies' PVC recycling activities. However, their vinyl chloride monomer (VCM) plants, and Hoechst's Kalle PVC film business, have been left out. Erich Schnitzler, head of Hoechst's PVC business unit, does not anticipate problems with the European Community's competition directorate. We are both among the middle-sized European PVC producers, and together we would have a 9%-10% market share. Our jointmore » venture would not limit competition. Both partners are hoping for approval from Brussels in first-quarter 1993. Hoechst has 255,000 m.t./year of PVC capacity at Gendorfand Knapsack, while Wacker has 365,000 m.t./year at Burghausen and Cologne. All the units, except Wacker's Cologne plant, are back integrated to VCM. The joint venture would buy VCM from the two parent companies and on the merchant market.« less

  2. The costs and benefits of a cigarette ban.

    PubMed

    Doucet, Mathieu

    2017-06-01

    The death toll from tobacco is staggering: it might contribute to one billion premature deaths over the course of the 21st century. In 'The case for banning cigarettes', Kalle Grill and Kristin Voigt argue that the well-being and equality benefits of a complete ban on cigarettes more than justify the restrictions on autonomy that such a ban would impose. Their argument depends on two crucial simplifications: an assumption that the ban would be effective and the restriction of the analysis to a comparison with the status quo, rather than a broader range of policy options. I argue that despite the authors' claims, these two simplifications make it impossible for their argument to 'bring into focus the fundamental normative issues' surrounding a possible cigarette ban, since they dramatically overstate the benefits and obscure the most significant costs of such a ban. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  3. Inferring patterns of folktale diffusion using genomic data

    PubMed Central

    Bortolini, Eugenio; Pagani, Luca; Sarno, Stefania; Boattini, Alessio; Sazzini, Marco; da Silva, Sara Graça; Martini, Gessica; Metspalu, Mait; Pettener, Davide; Luiselli, Donata; Tehrani, Jamshid J.

    2017-01-01

    Observable patterns of cultural variation are consistently intertwined with demic movements, cultural diffusion, and adaptation to different ecological contexts [Cavalli-Sforza and Feldman (1981) Cultural Transmission and Evolution: A Quantitative Approach; Boyd and Richerson (1985) Culture and the Evolutionary Process]. The quantitative study of gene–culture coevolution has focused in particular on the mechanisms responsible for change in frequency and attributes of cultural traits, the spread of cultural information through demic and cultural diffusion, and detecting relationships between genetic and cultural lineages. Here, we make use of worldwide whole-genome sequences [Pagani et al. (2016) Nature 538:238–242] to assess the impact of processes involving population movement and replacement on cultural diversity, focusing on the variability observed in folktale traditions (n = 596) [Uther (2004) The Types of International Folktales: A Classification and Bibliography. Based on the System of Antti Aarne and Stith Thompson] in Eurasia. We find that a model of cultural diffusion predicted by isolation-by-distance alone is not sufficient to explain the observed patterns, especially at small spatial scales (up to ∼4,000 km). We also provide an empirical approach to infer presence and impact of ethnolinguistic barriers preventing the unbiased transmission of both genetic and cultural information. After correcting for the effect of ethnolinguistic boundaries, we show that, of the alternative models that we propose, the one entailing cultural diffusion biased by linguistic differences is the most plausible. Additionally, we identify 15 tales that are more likely to be predominantly transmitted through population movement and replacement and locate putative focal areas for a set of tales that are spread worldwide. PMID:28784786

  4. Inferring patterns of folktale diffusion using genomic data.

    PubMed

    Bortolini, Eugenio; Pagani, Luca; Crema, Enrico R; Sarno, Stefania; Barbieri, Chiara; Boattini, Alessio; Sazzini, Marco; da Silva, Sara Graça; Martini, Gessica; Metspalu, Mait; Pettener, Davide; Luiselli, Donata; Tehrani, Jamshid J

    2017-08-22

    Observable patterns of cultural variation are consistently intertwined with demic movements, cultural diffusion, and adaptation to different ecological contexts [Cavalli-Sforza and Feldman (1981) Cultural Transmission and Evolution: A Quantitative Approach ; Boyd and Richerson (1985) Culture and the Evolutionary Process ]. The quantitative study of gene-culture coevolution has focused in particular on the mechanisms responsible for change in frequency and attributes of cultural traits, the spread of cultural information through demic and cultural diffusion, and detecting relationships between genetic and cultural lineages. Here, we make use of worldwide whole-genome sequences [Pagani et al. (2016) Nature 538:238-242] to assess the impact of processes involving population movement and replacement on cultural diversity, focusing on the variability observed in folktale traditions ( n  = 596) [Uther (2004) The Types of International Folktales: A Classification and Bibliography. Based on the System of Antti Aarne and Stith Thompson ] in Eurasia. We find that a model of cultural diffusion predicted by isolation-by-distance alone is not sufficient to explain the observed patterns, especially at small spatial scales (up to [Formula: see text]4,000 km). We also provide an empirical approach to infer presence and impact of ethnolinguistic barriers preventing the unbiased transmission of both genetic and cultural information. After correcting for the effect of ethnolinguistic boundaries, we show that, of the alternative models that we propose, the one entailing cultural diffusion biased by linguistic differences is the most plausible. Additionally, we identify 15 tales that are more likely to be predominantly transmitted through population movement and replacement and locate putative focal areas for a set of tales that are spread worldwide.

  5. Chemistry of the Marlboro Clay in Virginia and Implications for the Paleocene-Eocene Thermal Maximum

    NASA Astrophysics Data System (ADS)

    Zimmer, M.; Cai, Y.; Corley, A.; Liang, J. A.; Powars, D.; Goldstein, S. L.; Kent, D. V.; Broecker, W. S.

    2017-12-01

    The Paleocene-Eocene Thermal Maximum (PETM) was a global hyperthermal ( 5ºC warming) event marked by a rapid carbon isotope excursion (CIE) of >1‰ in the marine carbonate record (e.g. Zeebe et al. Nature Geoscience 2009). Possible explanations for the CIE include intrusion of a sill complex into organic carbonate (Aarnes et al. J. Geol. Soc. 2015), dissolution of methane hydrates (Thomas et al. Geology 2002), and a comet impact event (Schaller et al. Science 2016). Here we present new data across the PETM from the VirginiaDEQ-USGS Surprise Hill (SH) core, Northumberland Co., VA. We analyzed the Marlboro Clay, a thick, kaolinite-rich clay unit that marks the initiation of the PETM in the mid-Atlantic Coastal Plain of North America, as well as units above and below it. Bulk sediment records a δ13C excursion of approximately -5‰ across the CIE, while benthic foraminifera (Cibicidoides spp.) record a synchronous excursion of approximately -4.5‰. These results are consistent with other records from the New Jersey Coastal Plain (Makarova et al. Paleoceanography 2017). The excursion coincides with an increase in magnetic susceptibility, a decrease in bulk CaCO3 content, and an 2.5‰ decrease of δ18O in both the bulk sediment and benthic foraminifera of the SH core. Pb isotope analyses of the <63 μm fraction sediments indicate a unique provenance make-up for the Marlboro Clay. The results of the study thus indicate that PETM Marlboro Clay was not generated simply by intensified weathering of the same source area as the underlying Aquia Formation and overlying Nanjemoy Formation. Any hypothesis that aims to explain the mechanism that triggered the PETM must also account for the observed distinct provenance make-up of the Marlboro Clay.

  6. Uncertainty estimation of predictions of peptides' chromatographic retention times in shotgun proteomics.

    PubMed

    Maboudi Afkham, Heydar; Qiu, Xuanbin; The, Matthew; Käll, Lukas

    2017-02-15

    Liquid chromatography is frequently used as a means to reduce the complexity of peptide-mixtures in shotgun proteomics. For such systems, the time when a peptide is released from a chromatography column and registered in the mass spectrometer is referred to as the peptide's retention time . Using heuristics or machine learning techniques, previous studies have demonstrated that it is possible to predict the retention time of a peptide from its amino acid sequence. In this paper, we are applying Gaussian Process Regression to the feature representation of a previously described predictor E lude . Using this framework, we demonstrate that it is possible to estimate the uncertainty of the prediction made by the model. Here we show how this uncertainty relates to the actual error of the prediction. In our experiments, we observe a strong correlation between the estimated uncertainty provided by Gaussian Process Regression and the actual prediction error. This relation provides us with new means for assessment of the predictions. We demonstrate how a subset of the peptides can be selected with lower prediction error compared to the whole set. We also demonstrate how such predicted standard deviations can be used for designing adaptive windowing strategies. lukas.kall@scilifelab.se. Our software and the data used in our experiments is publicly available and can be downloaded from https://github.com/statisticalbiotechnology/GPTime . © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  7. Complex Systems: Control and Modeling Problems

    DTIC Science & Technology

    2004-08-23

    von Mat- thias Kalle Dalheimer. - 4. Aufl.. - Beijing ; Koln : O’Reilly, 2003. - XVII, 1084 S.; (dt.) ISBN 3-89721- 332-X Original: Java in a...Берлин: Техник, 1988. [7] Форрестер Д. Основы кибернетики предприятия (индустриальная динамика): Пер. с англ. – М.: Про- гресс, 1971 . 385...размерности системы уравнений для синтеза оптимального управления. Оптимальные и самонастраивающиеся системы. – Новосибирск: Изд. ИАиЭ АН СССР, 1971

  8. Spectrofluorimetric determination of melatonin in kernels of four different Pistacia varieties after ultrasound-assisted solid-liquid extraction.

    PubMed

    Oladi, Elham; Mohamadi, Maryam; Shamspur, Tayebeh; Mostafavi, Ali

    2014-11-11

    Melatonin is normally consumed to regulate the body's biological cycle. However it also has therapeutic properties, such as anti-tumor, anti-aging and protects the immune system. There are some reports on the presence of melatonin in edible kernels such as walnuts, but the extraction of melatonin from pistachio kernels is reported here for the first time. For this, the methanolic extract of pistachio kernels was exposed to gas chromatography/mass spectrometry analysis which confirmed the presence of melatonin. A fluorescence-based method was applied for the determination of melatonin in different extracts. When excited at λ=275 nm, the fluorescence emission intensity of melatonin was measured at λ=366 nm. Ultrasound-assisted solid-liquid extraction was used for the extraction of melatonin from pistachio kernels prior to fluorimetric determination. To achieve the highest extraction recovery, the main parameters affecting the extraction efficiency such as extracting solvent type and volume, temperature, sonication time and pH were evaluated. Under the optimized conditions, a linear dependence of fluorescence intensity on melatonin concentration was observed in the range of 0.0040-0.160 μg mL(-1), with a detection limit of 0.0036 μg mL(-1). This method was applied successfully for measuring and comparing the melatonin content in the kernels of four different varieties of Pistacia including Ahmad Aghaei, Akbari, Kalle Qouchi and Fandoghi. In addition, the results obtained were compared with those obtained using GC/MS. A good agreement was observed indicating the reliability of the proposed method. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Spectrofluorimetric determination of melatonin in kernels of four different Pistacia varieties after ultrasound-assisted solid-liquid extraction

    NASA Astrophysics Data System (ADS)

    Oladi, Elham; Mohamadi, Maryam; Shamspur, Tayebeh; Mostafavi, Ali

    2014-11-01

    Melatonin is normally consumed to regulate the body's biological cycle. However it also has therapeutic properties, such as anti-tumor, anti-aging and protects the immune system. There are some reports on the presence of melatonin in edible kernels such as walnuts, but the extraction of melatonin from pistachio kernels is reported here for the first time. For this, the methanolic extract of pistachio kernels was exposed to gas chromatography/mass spectrometry analysis which confirmed the presence of melatonin. A fluorescence-based method was applied for the determination of melatonin in different extracts. When excited at λ = 275 nm, the fluorescence emission intensity of melatonin was measured at λ = 366 nm. Ultrasound-assisted solid-liquid extraction was used for the extraction of melatonin from pistachio kernels prior to fluorimetric determination. To achieve the highest extraction recovery, the main parameters affecting the extraction efficiency such as extracting solvent type and volume, temperature, sonication time and pH were evaluated. Under the optimized conditions, a linear dependence of fluorescence intensity on melatonin concentration was observed in the range of 0.0040-0.160 μg mL-1, with a detection limit of 0.0036 μg mL-1. This method was applied successfully for measuring and comparing the melatonin content in the kernels of four different varieties of Pistacia including Ahmad Aghaei, Akbari, Kalle Qouchi and Fandoghi. In addition, the results obtained were compared with those obtained using GC/MS. A good agreement was observed indicating the reliability of the proposed method.

  10. Sensitivity of annual mass balance gradient and Hypsometry to the changing climate: the case of Dokriani Glacier, central Himalaya, India

    NASA Astrophysics Data System (ADS)

    Pratap, B.

    2015-12-01

    The glacier mass balance is undelayed, unfiltered and direct method to assess the impact of climate change on the glaciers. Many studies suggest that some of the Himalayan glaciers have lost their mass at an increased rate during the past few decades. Furthermore, the mass balance gradient and hypsometric analysis are important to understand the glacier response towards climatic perturbations. Our long term in-situ monitoring on the Dokriani Glacier provides great insights to understand the variability in central Himalayan glaciers. We report the relationship between glacier hypsometry and annual mass balance gradient (12 years) to understand the glacier's response towards climate change. Dokriani Glacier in the Bhagirathi basin is a small (7 km2) NNW exposed glacier in the western part of central Himalaya, India. The study analysed the annual balance, mass balance gradient and length changes observed during first decade of 21st century (2007-2013) and compare with the previous observations of 1990s (1992-2000). A large spatial variability in the mass balance gradients of two different periods has been observed. The equilibrium-line altitude (ELA) was fluctuated between 5000 and 5100 m a.s.l. and the derived time averaged ELA (ELAn) and balance budget ELA (ELA0) were 5075 and 4965 m a.s.l respectively during 1992-2013. The observed time-averaged accumulation-area ratio (AARn) and balance budget AAR (AAR0) were 0.67 and 0.72 respectively during 1992-2013. The higher value of AAR comprises due to flat and broader accumulation area (4.50 km2) of the glacier. Although, having larger accumulation area, the glacier has faced strong mass wasting with average annual ablation of -1.82 m w.e. a-1 in the ablation zone as compare to residual average annual accumulation of 0.41 m w.e. a-1. Based on the annual mass balance series (12 years) Dokriani Glacier has continuous negative annual balances with monotonically negative cumulative mass loss of -3.86 m w.e with the average

  11. A Genetic Basis for Functional Hypothalamic Amenorrhea

    PubMed Central

    Caronia, Lisa M.; Martin, Cecilia; Welt, Corrine K.; Sykiotis, Gerasimos P.; Quinton, Richard; Thambundit, Apisadaporn; Avbelj, Magdalena; Dhruvakumar, Sadhana; Plummer, Lacey; Hughes, Virginia A.; Seminara, Stephanie B.; Boepple, Paul A.; Sidis, Yisrael; Crowley, William F.; Martin, Kathryn A.; Hall, Janet E.; Pitteloud, Nelly

    2011-01-01

    BACKGROUND Functional hypothalamic amenorrhea is a reversible form of gonadotropin-releasing hormone (GnRH) deficiency commonly triggered by stressors such as excessive exercise, nutritional deficits, or psychological distress. Women vary in their susceptibility to inhibition of the reproductive axis by such stressors, but it is unknown whether this variability reflects a genetic predisposition to hypothalamic amenorrhea. We hypothesized that mutations in genes involved in idiopathic hypogonadotropic hypogonadism, a congenital form of GnRH deficiency, are associated with hypothalamic amenorrhea. METHODS We analyzed the coding sequence of genes associated with idiopathic hypogonadotropic hypogonadism in 55 women with hypothalamic amenorrhea and performed in vitro studies of the identified mutations. RESULTS Six heterozygous mutations were identified in 7 of the 55 patients with hypothalamic amenorrhea: two variants in the fibroblast growth factor receptor 1 gene FGFR1 (G260E and R756H), two in the prokineticin receptor 2 gene PROKR2 (R85H and L173R), one in the GnRH receptor gene GNRHR (R262Q), and one in the Kall-mann syndrome 1 sequence gene KAL1 (V371I). No mutations were found in a cohort of 422 controls with normal menstrual cycles. In vitro studies showed that FGFR1 G260E, FGFR1 R756H, and PROKR2 R85H are loss-of-function mutations, as has been previously shown for PROKR2 L173R and GNRHR R262Q. CONCLUSIONS Rare variants in genes associated with idiopathic hypogonadotropic hypogonadism are found in women with hypothalamic amenorrhea, suggesting that these mutations may contribute to the variable susceptibility of women to the functional changes in GnRH secretion that characterize hypothalamic amenorrhea. Our observations provide evidence for the role of rare variants in common multifactorial disease. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and others; ClinicalTrials.gov number, NCT00494169.) PMID:21247312

  12. Evaluating potentials for future generation off-shore wind-power outside Norway

    NASA Astrophysics Data System (ADS)

    Benestad, R. E.; Haugen, J.; Haakenstad, H.

    2012-12-01

    With todays critical need of renewable energy sources, it is naturally to look towards wind power. With the long coast of Norway, there is a large potential for wind farms offshore Norway. Although there are more challenges with offshore wind energy installations compared to wind farms on land, the offshore wind is generally higher, and there is also higher persistence of wind speed values in the power generating classes. I planning offshore wind farms, there is a need of evaluation of the wind resources, the wind climatology and possible future changes. In this aspect, we use data from regional climate model runs performed in the European ENSEMBLE-project (van der Linden and J.F.B. Mitchell, 2009). In spite of increased reliability in RCMs in the recent years, the simulations still suffer from systematic model errors, therefore the data has to be corrected before using them in wind resource analyses. In correcting the wind speeds from the RCMs, we will use wind speeds from a Norwegian high resolution wind- and wave- archive, NORA10 (Reistad et al 2010), to do quantile mapping (Themeβl et. al. 2012). The quantile mapping is performed individually for each regional simulation driven by ERA40-reanalysis from the ENSEMBLE-project corrected against NORA10. The same calibration is then used to the belonging regional climate scenario. The calibration is done for each grid cell in the domain and for each day of the year centered in a +/-15 day window to make an empirical cumulative density function for each day of the year. The quantile mapping of the scenarios provide us with a new wind speed data set for the future, more correct compared to the raw ENSEMBLE scenarios. References: Reistad M., Ø. Breivik, H. Haakenstad, O. J. Aarnes, B. R. Furevik and J-R Bidlo, 2010, A high-resolution hindcast of wind and waves for The North Sea, The Norwegian Sea and The Barents Sea. J. Geophys. Res., 116. doi:10.1029/2010JC006402. Themessl M. J., A. Gobiet and A. Leuprecht, 2012

  13. Long-term coastal measurements for large-scale climate trends characterization

    NASA Astrophysics Data System (ADS)

    Pomaro, Angela; Cavaleri, Luigi; Lionello, Piero

    2017-04-01

    , making it difficult, if not impossible, to distinguish the imposed effects from the climate signal itself, as demonstrated by Aarnes et al. (2015). From this point of view the problem is that long-term measured datasets are relatively unique, due to the cost and technical difficulty of maintaining fixed instrumental equipment over time, as well as of assuring the homogeneity and availability of the entire dataset. For this reason we are furthermore working on the publication of the quality controlled dataset to make it widely available for open-access research purposes. The analysis and homogenization of the original dataset has actually required a substantial part of the time spent on the study, because of the strong impact that the quality of the data may have on the final result. We consider this particularly relevant, especially when referring to coastal areas, where the lack of reliable satellite data makes it difficult to improve the model capability to resolve the local peculiar oceanographic processes. We describe in detail any step and procedure used in producing the data, including full descriptions of the experimental design, data acquisition assays, and any computational processing needed to support the technical quality of the dataset.

  14. A Skin Cancer Prevention Facial-Aging Mobile App for Secondary Schools in Brazil: Appearance-Focused Interventional Study.

    PubMed

    Brinker, Titus Josef; Heckl, Marlene; Gatzka, Martina; Heppt, Markus V; Resende Rodrigues, Henrique; Schneider, Sven; Sondermann, Wiebke; de Almeida E Silva, Carolina; Kirchberger, Michael C; Klode, Joachim; Enk, Alexander H; Knispel, Sarah; von Kalle, Christof; Stoffels, Ingo; Schadendorf, Dirk; Nakamura, Yasuhiro; Esser, Stefan; Assis, Aisllan; Bernardes-Souza, Breno

    2018-03-09

    , 87.2% agreement in males) and increased use of sun protection (n=197, 92.1% agreement in females vs n=123, 87.2% agreement in males) and independent of age or skin type. All medical students involved filled in a process evaluation revealing that they all perceived the intervention as effective and unproblematic, and that all pupils tried the app in their presence. The photoaging intervention was effective in changing behavioral predictors for UV protection in Brazilian adolescents. The predictors measured indicated an even higher prospective effectiveness in southeast Brazil than in Germany (>90% agreement in Brazil vs >60% agreement in Germany to both items that measured motivation to reduce UV exposure) in accordance with the theory of planned behavior. Medical students are capable of complete implementation. A randomized controlled trial measuring prospective effects in Brazil is planned as a result of this study. ©Titus Josef Brinker, Marlene Heckl, Martina Gatzka, Markus V Heppt, Henrique Resende Rodrigues, Sven Schneider, Wiebke Sondermann, Carolina de Almeida e Silva, Michael C Kirchberger, Joachim Klode, Alexander H Enk, Sarah Knispel, Christof von Kalle, Ingo Stoffels, Dirk Schadendorf, Yasuhiro Nakamura, Stefan Esser, Aisllan Assis, Breno Bernardes-Souza. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 09.03.2018.

  15. EDITORIAL: Molecular switches at surfaces Molecular switches at surfaces

    NASA Astrophysics Data System (ADS)

    Weinelt, Martin; von Oppen, Felix

    2012-10-01

    electron-vibration coupling in transport through single moleculesKatharina J Franke and Jose Ignacio Pascual Vibrational heating in single-molecule switches: an energy-dependent density-of-states approachT Brumme, R Gutierrez and G Cuniberti Reversible switching of single tin phthalocyanine molecules on the InAs(111)A surfaceC Nacci, K Kanisawa and S Fölsch Tuning the interaction between carbon nanotubes and dipole switches: the influence of the change of the nanotube-spiropyran distanceP Bluemmel, A Setaro, C Maity, S Hecht and S Reich Carbon nanotubes as substrates for molecular spiropyran-based switchesE Malic, A Setaro, P Bluemmel, Carlos F Sanz-Navarro, Pablo Ordejón, S Reich and A Knorr Ultrafast dynamics of dithienylethenes differently linked to the surface of TiO2 nanoparticlesLars Dworak, Marc Zastrow, Gehad Zeyat, Karola Rück-Braun and Josef Wachtveitl Switching the electronic properties of Co-octaethylporphyrin molecules on oxygen-covered Ni films by NO adsorptionC F Hermanns, M Bernien, A Krüger, J Miguel and W Kuch STM-switching of organic molecules on semiconductor surfaces: an above threshold density matrix model for 1,5 cyclooctadiene on Si(100)K Zenichowski, Ch Nacci, S Fölsch, J Dokić, T Klamroth and P Saalfrank A switch based on self-assembled thymineFatih Kalkan, Michael Mehlhorn and Karina Morgenstern The growth and electronic structure of azobenzene-based functional molecules on layered crystalsJ Iwicki, E Ludwig, J Buck, M Kalläne, F Köhler, R Herges, L Kipp and K Rossnagel Voltage-dependent conductance states of a single-molecule junctionY F Wang, N Néel, J Kröger, H Vázquez, M Brandbyge, B Wang and R Berndt Molecules with multiple switching units on a Au(111) surface: self-organization and single-molecule manipulationJohannes Mielke, Sofia Selvanathan, Maike Peters, Jutta Schwarz, Stefan Hecht and Leonhard Grill Preparing and regulating a bi-stable molecular switch by atomic manipulationS Sakulsermsuk, R E Palmer and P A Sloan Mixed self

  16. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

    NASA Astrophysics Data System (ADS)

    Bozic, Mirjana; Man'ko, Margarita

    2009-09-01

    Kalle-Antti Suominen (http://www.congress.utu.fi/cewqo2009). The conference site is the new ICT building at chaired by Professor Kalle-Antti Suominen (http://www.congress.utu.fi/cewqo2009, www.congress.utu.fi/cewqo2009). The conference site was the new ICT building at the University of Turku campus area and the Viking Line ferry boat. Turku is the central city of historical Finland established on the mouth of the river Aura in the 13th century. It is the birthplace of Finnish academic life, since the Academy of Turku was established there in 1640. In 2011, Turku will be one of the cultural capitals of Europe. The city has a strong maritime tradition and is shielded from the Baltic sea by a large and beautiful archipelago. The 17th Central European Workshop on Quantum Optics will be held in 2010 in St Andrews, UK. It will be chaired by Professors Ulf Leonhardt and Natalia Korolkova from the School of Physics and Astronomy, University of St Andrews. St Andrews is home to the first university of Scotland, the third-oldest in the English-speaking world, and is the home of golf. It remains a charming, eccentric seaside town that is sufficiently secluded - the ideal place for a stimulating and thought-provoking conference.

  17. FOREWORD: The 70th birthday of Professor Stig Stenholm The 70th birthday of Professor Stig Stenholm

    NASA Astrophysics Data System (ADS)

    Suominen, Kalle-Antti

    2010-09-01

    information [7] and in Stockholm he had, again, very successful postdocs such as Ulf Leonhardt. Finally, in 2005, Stig Stenholm retired, although he is still active, writing papers, taking part in conferences and making research visits. We honoured his 70th birthday at the CEWQO2009 conference, and hope that the future provides us with further opportunities for such events. Looking at the obituary of Dirk ter Haar, I see that his style with students reminds me of Stig's approach. In my opinion, Stig expects independence and initiative from a student, giving perhaps a broad topic in which the student is expected to find his or her own way, whilst working perhaps with a postdoc. Juha Javanainen has talked about the 'sink or swim' style (not referring to Stig, though). There is a famous series of children's books about Moomin trolls by Tove Jansson (another Swedish-speaking Finn like Stig). In one of them, the Moomin find in early spring a small flower in a patch of land uncovered by snow, pushing its way up. One of them wants to cover it against frost during the night, but another says 'Don't, it'll fare better later if it has some difficulties at first'. At CEWQO2009 Stig gave the full list of his finished PhD students: Rainer Salomaa (1973), Temba Dlodlo (1980), Juha Javanainen (1980), Markus Lindberg (1985), Matti Kaivola (1985), Birger Ståhlberg (1985), Kalle-Antti Suominen (1992), Mackillo Kira (1995), Päivi Törmä (1996), Asta Paloviita (1997), Patrik Öhberg (1998), Martti Havukainen (1999), Erika Andersson (2000), Pawel Piwnicki (2001), Åsa Larson (2001), Markku Jääskeläinen (2003), and Jonas Larson (2005). One should also mention Erkki Kyrölä, who eventually graduated at Rochester and Olli Serimaa, who never graduated but published some important early-stage laser cooling work. As a final note I must mention a passion that Stig and I share, namely books. I have nearly 400 professional physics and mathematics books, but I am certain that the size of Stig

  18. Commentary on "integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer." Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weichenhan D, Minner S, Wuttig D, Warnatz HJ, Stehr H, Rausch T, Jäger N, Gu L, Bogatyrova O, Stütz AM, Claus R, Eils J, Eils R, Gerhäuser C, Huang PH, Hutter B, Kabbe R, Lawerenz C, Radomski S, Bartholomae CC, Fälth M, Gade S, Schmidt M, Amschler N, Haß T, Galal R, Gjoni J, Kuner R, Baer C, Masser S, von Kalle C, Zichner T, Benes V, Raeder B, Mader M, Amstislavskiy V, Avci M, Lehrach H, Parkhomchuk D, Sultan M, Burkhardt L, Graefen M, Huland H, Kluth M, Krohn A, Sirma H, Stumm L, Steurer S, Grupp K, Sültmann H, Sauter G, Plass C, Brors B, Yaspo ML, Korbel JO, Schlomm T, Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.: Cancer Cell 2013;23(2):159-70.

    PubMed

    Olumi, Aria F

    2014-02-01

    Early-onset prostate cancer (EO-PCA) represents the earliest clinical manifestation of prostate cancer. To compare the genomic alteration landscapes of EO-PCA with "classical" (elderly-onset) PCA, we performed deep sequencing-based genomics analyses in 11 tumors diagnosed at young age, and pursued comparative assessments with seven elderly-onset PCA genomes. Remarkable age-related differences in structural rearrangement (SR) formation became evident, suggesting distinct disease pathomechanisms. Whereas EO-PCAs harbored a prevalence of balanced SRs, with a specific abundance of androgen-regulated ETS gene fusions including TMPRSS2:ERG, elderly-onset PCAs displayed primarily non-androgen-associated SRs. Data from a validation cohort of>10,000 patients showed age-dependent androgen receptor levels and a prevalence of SRs affecting androgen-regulated genes, further substantiating the activity of a characteristic "androgen-type" pathomechanism in EO-PCA. Copyright © 2014 Elsevier Inc. All rights reserved.