5-17-06 NIH-AARP Diet and Health Study Chart Characteristics The demographic and nutritional tables (Tables 2 and 3) from the baseline paper are below. Of the 617,119 surveys returned, 545,784 were used to create these tables. To obtain the most
Cancer.gov
BackgroundIn most populations, incidence rates of upper gastrointestinal tract cancers (UGI: head and neck, esophagus, and stomach) are higher among men than among women. Established risk factors do not appear to explain these differences, suggesting a possible role for sex hormones.Methods201,506 women of the NIH-AARP Diet and Health cohort completed a ...
PubMed Central
Background: We hypothesized that diabetes may play a role in thyroid cancer risk due to the parallel secular rise in diabetes prevalence and morbidity in the United States, the higher prevalence of thyroid disorders among diabetics compared with the general population, and the potential roles of metabolic syndrome, obesity, and diabetes as precipitating factors in cancer development. Methods: We ...
PubMed
Diet&Health Stud� Ne�sPublished for Study Participants by the National Cancer Institute Fall 2006 A Hear�fel� Thank� Dear Participant, My team and I are indebted to you and your fellow cohort members for your continued participation in the NIH-AARP Diet
Use this codebook as a guide when configuring your scanner or data entry system to create data files for DHQ1.2007 questionnaires that use a one-character frequency format.
Use this codebook as a guide when configuring your scanner or data entry system to create data files for DHQ1.2002 questionnaires that use a one-character frequency format.
We investigated the association of dietary ?-tocopherol, ?-tocopherol, and supplemental vitamin E intake with the risk of esophageal squamous cell carcinoma (ESCC; n = 158), esophageal adenocarcinoma (EAC; n = 382), gastric cardia adenocarcinoma (GCA; n = 320), and gastric noncardia adenocarcinoma (GNCA; n = 327) in the NIH-AARP Diet and Health Study, a ...
Several case-control studies have suggested that non-steroidal anti-inflammatory drugs (NSAIDs) reduce risk for glioblastoma, an aggressive form of brain cancer. Prospective investigations have not observed such an association, but these studies lacked adequate brain cancer case numbers, and did not stratify by histologic subtype. We prospectively investigated the association between NSAID use and ...
Ovarian cancer is a leading cause of cancer death among women in the United States and it has the highest mortality rate of all gynecologic cancers. Internationally, there is a five-fold variation in incidence and mortality of ovarian cancer, which suggests a role for environmental factors, including diet. Nitrate and nitrite are found in various food items and they are precursors of N-nitroso ...
... Title : The Physical and Mental Health of A Large Military Cohort: Baseline Functional Health Status of the Millennium Cohort. ...
DTIC Science & Technology
Background: Epidemiologic data on the combined influence of several lifestyle factors on diabetes risk are rare, particularly among older adults. Objective: To examine how combinations of lifestyle risk factors relate to the 11-year risk for incident diabetes. Design: Population-based prospective cohort study. Setting: National Institutes of Health ...
The NIH-AARP Diet and Health Study examined the relations of body mass index (BMI) and physical activity to thyroid cancer in a prospective cohort. Results support an adverse effect of adiposity on risk for developing total and papillary, and possibly follicular thyroid cancers. Based on only 15 cases, adiposity was unrelated to medullary thyroid cancers. ...
The NIH-AARP Diet and Health Study prospectively investigated the relations of self-reported moderate and vigorous physical activity and body mass index (BMI) to ovarian cancer. Neither moderate nor vigorous physical activity showed a statistically significant association with ovarian cancer in this large cohort of women. Researchers suspect that obesity ...
... al. Meat intake and cooking techniques: Associations with pancreatic cancer. Mutation Research 2002; 506�507:225�231. [ PubMed ... et al. Meat and meat-mutagen intake and pancreatic cancer risk in the NIH-AARP cohort. Cancer Epidemiology, ...
MedlinePLUS
Aug 29, 2008 ... NASA and AARP Celebrate 50 Years of Inspiration, Innovation and Discovery. WASHINGTON -- NASA will join AARP in their Life at 50+ National ...
NASA Website
Dietary guidelines advise consumers to limit intake of red meat and choose lean protein sources, such as poultry and fish. Poultry consumption has been steadily increasing in the U.S., but the effect on cancer risk remains unclear. In a large U.S. cohort, we prospectively investigated poultry and fish intake and cancer risk across a range of malignancies in men and women. Diet ...
Diets with high glycemic index and glycemic load have been associated with insulin resistance. Insulin resistance has been implicated in the etiology of pancreatic cancer. We prospectively investigated the associations between glycemic index, carbohydrates, glycemic load, and available carbohydrates dietary constituents (starch and simple sugar) intake and the risk of pancreatic cancer. We ...
The NIH-AARP Diet and Health Study analyzed the association between body mass index (BMI) and physical activity to renal cell cancer (RCC). Weight gain in early (18-35 years of age) and mid- (35-50 years of age) adulthood was strongly associated with RCC, whereas weight gain after midlife (age 50 years to baseline) was unrelated. Waist-to-hip ratio was ...
... However, the higher prevalence of alcohol abuse and the disproportionately higher burden of mental disorders among some subgroups ...
Page 1. LONGITUDINAL INVESTIGATION OF RETENTION AMONG ARMY RESERVE SOLDIERS: BASELINE STUDY OF JUNE 2001 COHORT ...
Fisher, Linda; Montenegro, Xenia; Remez, Shereen (2002). "Staying ahead of the curve: The AARP work and career study. A National survey conducted for AARP ...
The NIH-AARP Diet and Health Study was developed at the National Cancer Institute of the National Institutes of Health to improve our understanding of the relationship between diet and health.
benefits (including health insurance), and retirement. In regard to benefits, for example, AARP said Baptist Health South Florida, the largest not-for- ...
The Cohort Consortium includes investigators responsible for 41 high-quality cohorts involving more than 4 million people. The cohorts are international in scope and cover large and diverse populations. Extensive risk factor data are available on each cohort, and biospecimens including germline DNA collected at ...
... Title : The Effect of a Monocular Helmet-Mounted Display on Aircrew Health: A Cohort Study of Apache AH Mk1 Pilits Two-Year Baseline Review. ...
... 4 Page 5. Among the subjects (N=15) enrolled in study AL-02/03, one subject in each treatment cohort did not have detectable serum venom levels at baseline. ...
Center for Biologics Evaluation and Research (CBER)
The relation between diet, lifestyle, and acute myeloid leukemia was assessed in a US cohort of 491,163 persons from the NIH-AARP Diet and Health Study (1995-2003). A total of 338 incident cases of acute myeloid leukemia were ascertained. Multivariate Cox models were utilized to estimate hazard ratios and 95% confidence intervals. Compared with those for ...
The relation between diet, lifestyle, and acute myeloid leukemia was assessed in a US cohort of 491,163 persons from the NIH�AARP Diet and Health Study (1995�2003). A total of 338 incident cases of acute myeloid leukemia were ascertained. Multivariate Cox models were utilized to estimate hazard ratios and 95% confidence intervals. Compared with those ...
Background: Worldwide, thyroid cancer incidence rates are higher among women than men. While this suggests a possible etiologic role of female sex hormones, clear associations between hormonal and reproductive factors and thyroid cancer have not been observed. However, few large prospective studies have been conducted. Methods: Hazard ratios (HRs) and 95% confidence intervals (CIs) for hormonal ...
Objectives. We examined whether the risk of premature mortality associated with living in socioeconomically deprived neighborhoods varies according to the health status of individuals. Methods. Community-dwelling adults (n=566402; age=50-71 years) in 6 US states and 2 metropolitan areas participated in the ongoing prospective National Institutes of Health-AARP Diet and Health ...
Objective To determine if baseline functional health status, as measured by SF-36 (veterans), predicts new onset symptoms or diagnosis of post- traumatic stress disorder among deployed US military personnel with combat exposure. Design Prospective cohort ...
National Technical Information Service (NTIS)
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Objective: To describe new onset and persistence of PTSD symptoms in a large population-based military cohort, many of whom deployed in support of the Global War on Terrorism (GWOT). Design, Setting, and Participants: Millennium Cohort Study baseline enro...
... Ultimately, this too will have to be addressed in order to ensure that patients get the medication they need in a timely fashion. ...
Center for Drug Evaluation (CDER)
Adverse socioeconomic conditions, at both the individual and the neighborhood level, increase the risk of colorectal cancer (CRC) death, but little is known regarding whether CRC survival varies geographically and the extent to which area-level socioeconomic deprivation affects this geographic variation. Using data from the National Institutes of Health (NIH)-AARP Diet and ...
Previous investigations have provided conflicting results regarding whether alcohol consumption affects endometrial cancer risk, although in many of these studies the highest category of alcohol intake examined was limited. Further, most were unable to resolve how alcohol associations are affected by beverage type, the presence of other endometrial cancer risk factors, or tumor characteristics. To ...
Self-report data on smoking initiation (whether the respondent admitted ever having smoked) were obtained from three large adult twin samples (Australia, N = 3,808 pairs; Virginia, N = 2,145 pairs; AARP, N = 3,620 pairs). Data were broken down into birth cohorts, and genetic models were fitted to test whether the decline, in more recent birth ...
Nitrate and nitrite are precursors of N-nitroso compounds, which induce tumors of the pancreas in animals. The authors evaluated the relation of dietary nitrate and nitrite to pancreatic cancer risk in the NIH-AARP Diet and Health Study. Nitrate and nitrite intakes were assessed at baseline using a 124-item food frequency questionnaire. During ...
PurposeResiding in deprived areas may increase risk of mortality beyond that explained by a person's own SES-related factors and lifestyle. The aim of this study was to examine the relation between neighborhood socioeconomic deprivation and all-cause, cancer- and cardiovascular disease (CVD)-specific mortality for men and women after accounting for education and other important person-level risk ...
BackgroundDespite strong evidence of an inverse association of physical activity with postmenopausal breast cancer risk, whether a certain intensity or time of life of physical activity is most effective for lowering breast cancer risk is not known.MethodsIn 118,899 postmenopausal women in the prospective NIH-AARP Diet and Health Study, we examined the relations of light and ...
Increased fruit and vegetable consumption may protect against lung cancer, although epidemiologic findings are inconclusive. The authors prospectively examined associations between lung cancer risk and intakes of fruit, vegetables, and botanical subgroups in 472,081 participants aged 50-71 years in the National Institutes of Health (NIH)-AARP Diet and Health Study. Diet was ...
SummaryThere are differences in the risk profile of patients prescribed alendronate, risedronate, or ibandronate. Observed reductions in fracture incidence over time suggest that the effectiveness of each bisphosphonate in clinical practice has been consistent with their efficacies demonstrated in randomized controlled trials.IntroductionObservational studies of bisphosphonate effectiveness for ...
During the past several decades, an increasing incidence of thyroid cancer has been observed worldwide. Nitrate inhibits iodide uptake by the thyroid, potentially disrupting thyroid function. An increased risk of thyroid cancer associated with nitrate intake was recently reported in a cohort study of older women in Iowa. We evaluated dietary nitrate and nitrite intake and ...
... After controlling for sex, age, education, marital status, race/eth- nicity ... duty in Somalia for US military personnel. ... J Trauma Stress 1998;11(4):611e25 ...
The Longitudinal Study on Aging (LSOA) is designed to measure changes in fuctional ability and in living arrangements (including movement into and out of nursing homes) of a cohort of older people. The Version 3 file provides baseline and 4 years of follo...
In recognising the requirement to identify why junior Army Reserve (ARes) soldiers separate, the Directorate of Reserves - Army (DRES-A) sought to conduct a quantitative, longitudinal examination of new ARes soldiers. This examination entails the collecti...
Richmond, Virginia is one of twenty cities across the United States in which parents are participating in a study of 'Fragile Families and Child Wellbeing'. The study follows a new birth cohort of approximately 5000 children in an effort to learn more abo...
Philadelphia, Pennsylvania is one of twenty cities across the United States in which parents are participating in a study of Fragile Families and Child Wellbeing. The study follows a new birth cohort of approximately 5,000 children and their parents in an...
Detroit, Michigan is one of twenty cities across the United States in which parents are participating in a study of 'Fragile Families and Child Wellbeing'. The study follows a new birth cohort of approximately 5000 children in an effort to learn more abou...
Baltimore, Maryland is one of twenty cities across the United States in which parents are participating in a study of 'Fragile Families and Child Wellbeing'. The study follows a new birth cohort of approximately 5000 children in an effort to learn more ab...
Austin, Texas is one of twenty cities across the United States in which parents are participating in a study of 'Fragile Families and Child Wellbeing'. The study follows a new birth cohort of approximately 5000 children in an effort to learn more about th...
To investigate the allelic complexity of infection (COI) of Plasmodium falciparum infections in children living in western Kenya, samples from three studies were analyzed. The longitudinal cohort, used to determine the baseline COI, followed 60 children 1...
BackgroundWhen a therapy has been evaluated in the first clinical study, the outcome is often compared descriptively to outcomes in corresponding cohorts receiving other treatments. Such comparisons are often limited to selected studies, and often mix different outcomes and follow-up periods. Here we give an example of a systematic comparison to all ...
Recruiting a scientifically sound cohort of young men who have sex with men (YMSM) is an enduring research challenge. The few cohort studies that have been conducted to date on YMSM have relied on non-probability sampling methods to construct their cohorts. While these studies have provided valuable information about HIV risk behaviors ...
SummaryOver 73,700 adults age 40�79, nearly 70% African American, were recruited at community health centers across 12 southeastern states; individual characteristics were recorded and biologic specimens collected at baseline for later follow-up. The Southern Community Cohort Study is a unique national resource for assessing determinants of racial/ethnic ...
HEALTHY is a 3-year middle school intervention program designed to reduce risk factors for type 2 diabetes. The prevalence of diabetes risk factors at baseline in a cohort of 6,358 sixth-grade students is reported. Forty-two schools at seven U.S. sites were randomly assigned to intervention or contr...
Technology Transfer Automated Retrieval System (TEKTRAN)
Posttraumatic stress disorder (PTSD) results from experiencing or witnessing traumatic life-threatening events and is often associated with combat-related experiences. Baseline data from the Millennium Cohort collected from 74,947 members were analyzed to...
: targets and cohort competitor proportions increase and separate from the #12;9 rhyme and unrelated baseline course of fixation proportions to the target and competitors. Figure 1 about here These results suggest. compared frequency-matched targets that differed in number of cohort competitors and in neighborhood
E-print Network
The effect of military deployments to combat environments on disordered eating and weight changes is unknown. Using longitudinal data from Millennium Cohort Study participants who completed baseline (2001-2003) and follow-up (2004-2006) questionnaires (n=...
BackgroundUsing data from a case-control study, we previously reported that low dietary intakes of magnesium (Mg), iron (Fe), zinc (Zn), copper (Cu), but not selenium (Se) and calcium (Ca) were associated with increased lung cancer risk. Due to dietary recall bias in case-control studies our objective was to assess whether these findings hold in a prospective cohort ...
The objective of this study was to determine if baseline functional health status, as measured by SF-36 (veterans), predicts new onset symptoms or diagnosis of post-traumatic stress disorder among deployed US military personnel with combat exposure. Parti...
IntroductionAnkylosing spondylitis (AS) is a chronic rheumatic disease associated with spinal inflammation that subsequently leads to progression of structural damage and loss of function. The fully human anti-tumor necrosis factor (anti-TNF) antibody adalimumab reduces the signs and symptoms and improves overall quality of life in patients with active AS; these benefits have been maintained ...
Communities That Care (CTC) is a prevention system designed to reduce adolescent substance use and delinquency through the selection of effective preventive interventions tailored to a community�s specific profile of risk and protection. A community-randomized trial of CTC, the Community Youth Development Study, is currently being conducted in 24 communities across the United States. This paper ...
Some documents on this Web site are presented in Portable Document Format (PDF). On this site, the PDF format is used primarily for files that are large, or that are intended to be printed out.
... Sandra Eskin, AARP. Larry Ganslaw, American College of Cardiology. ... Edward Fotsch, Net Source Communications. Lawrence Ganslaw, American College of Cardiology. ...
... 10:50 to 12:05 pm Simultaneous Breakout Sessions Breakout Session: Enforcement Authorities Facilitator: William Correll, Working Group Lead Room A ...
Center for Food Safety and Applied Nutrition (CFSAN)
... Vice Chair, Import Implementation Team Leslie Kux, JD, Vice Chair, Import Implementation Team Charlotte Christin, JD, Import Work Group Lead: Third-Party ...
... Virgin Islands. for More inforMation about the new health Care law visit: www.acponline.org/aboutyourcoverage www.aarp. ...
The NIH-AARP Diet and Health Study examined physical activity in relation to lung cancer histologic types by smoking status. Increased physical activity appeared to be associated with a decrease in the risk of lung carcinoma.
... 434-2277 (publications on caregiving) www.aarp.org Administration on Aging ... you to complete a questionnaire to find federal, state, and local programs that you might be ...
your driving knowledge and skills. Some helpful resources include: SeniorDrivers.org (AAA) Driver Safety Program (AARP) Driving Decisions Workbook (University of Michigan)...
Science.gov Websites
The hypothesis that vitamin D is inversely associated with multiple health outcomes has been studied in the Harvard cohorts, including the Nurses' Health Study I (n=121,700 female nurses aged 37-64 at baseline in 1984), Nurses' Health Study II (n=116,671 female nurses aged 27-44 years at baseline in 1991), Health Professionals ...
Although many epidemiologists use the National Death Index (NDI) as the �gold standard� for ascertainment of US mortality, high search costs per year and per subject for large cohorts warrant consideration of less costly alternatives. In this study, for 1995�2001 deaths, the authors compared matches of a random sample of 11,968 National Institutes of Health ...
A previous analysis of the radon-related lung cancer mortality risk, in the German uranium miners cohort, using Poisson modeling techniques, noted internal (spontaneous) rates that were higher on average than the external rates by 16.5% (95% CI: 9%; 24%). The main purpose of the present paper is to investigate the nature of, and possible reasons for, this difference by ...
ObjectiveTo evaluate temporal trends in pediatric type 1 diabetes (T1DM) management and resultant effects on outcomes.Study designTwo pediatric T1DM cohorts were followed prospectively for 2 years and compared; Cohort 1 (N=299) was enrolled in 1997 and Cohort 2 (N=152) was enrolled in 2002. In both cohorts, ...
Although it is widely known that use of dietary supplements is common in the United States, little is known about use patterns among older Americans. The authors examined trends in dietary supplement use and its contribution to total nutrient intake in the Iowa Women's Health Study cohort in 1986 (baseline) and 2004 (follow-up). The proportion of women who ...
ABSTRACTBackground: Depression is a common disorder in late life. As the elderly population continues to grow worldwide, depression is also likely to become an increasing health problem. The aim of this study was to examine changes in prevalence of depression in various age cohorts over an 11-year period.Methods: This study involved two cross-sectional studies (HUNT 2 and HUNT ...
BackgroundValidated prediction scores are required to assess the risks of end-stage renal disease (ESRD) and death in individuals with chronic kidney disease (CKD).Study DesignProspective cohort study with validation in a separate cohort.Setting & ParticipantsCox regression was used to assess the relevance of baseline ...
Cancer is the second leading cause of death in postmenopausal women, and detailed epidemiological investigations are warranted to identify etiologic factors, including potentially modifiable risk factors. The Iowa Women's Health Study (IWHS) recruited a population-based cohort of 41,837 Iowa women, ages 55 to 69 years in 1986, to determine whether diet, body fat distribution, ...
BackgroundThe effect of alcohol portrayals and advertising on the drinking behaviour of young people is a matter of much debate. We evaluated the relationship between exposure to alcohol advertising, marketing and portrayal on subsequent drinking behaviour in young people by systematic review of cohort (longitudinal) studies.Methodsstudies were identified in October 2006 by ...
Epidemiological research often ascertains cancer history via self-reported questionnaires. We assessed the validity of self-reported cancer diagnoses in women born 1921-1926 recruited to the Australian Longitudinal Study in Women's Health (ALSWH) and determined the factors associated with false positive (FP) and false negative (FN) reporting. 4234 ALSWH cohort members were ...
OBJECTIVE: To evaluate the influence of inclusion criteria used in rheumatoid arthritis (RA) trials with adalimumab on clinical outcome and response. METHODS: The different inclusion criteria of published trials of adalimumab in RA were separately applied to a large prospective cohort of patients with RA treated with adalimumab (AdRA cohort), thereby ...
Objective. Treatment algorithms in RA include factors associated with poor prognosis; however, many patients remain erosion free despite years of disease. Our objective was to characterize the group of RA patients without erosions and identify its clinical predictors. Methods. Our study was conducted within a prospective observational cohort of RA patients recruited from the ...
ObjectiveTo define health outcomes of whiplash associated disorders (WAD) at three months, six months, and two years after injury and to examine predictors of these outcomes.DesignProspective cohort study.SettingNew South Wales, Australia.SubjectsPeople with compensable motor crash injuries who reported whiplash as one of their injuries.InterventionsNone.Main outcome ...
Smoking at least once or twice a month was assessed in the same cohort pre- and postintervention, with additional follow-ups later. Some differences in follow- up rates, not analyzed. Analysis of simple proportions smoking at each follow-up. At 4-year follow-up, smoking prevalence was significantly lower in both intervention groups, relative to the comparison group. At 8- and ...
The authors investigated the relationship between hot tea, iced tea, coffee and carbonated soft drinks consumption and upper gastrointestinal tract cancers risk in the NIH-AARP Study. During 2,584,953 person-years of follow-up on 481,563 subjects, 392 oral cavity, 178 pharynx, 307 larynx, 231 gastric cardia, 224 gastric non-cardia cancer, 123 Oesophageal Squamous Cell ...
The authors investigated the relationship between hot tea, iced tea, coffee and carbonated soft drinks consumption and upper gastrointestinal tract cancers risk in the NIH-AARP Study. During 2,584,953 person-years of follow-up on 481,563 subjects, 392 oral cavity, 178 pharynx, 307 larynx, 231 gastric cardia, 224 gastric noncardia cancer, 123 esophageal squamous cell carcinoma ...
Physical activity has been hypothesised to reduce endometrial cancer risk, but this relationship has been difficult to confirm because of a limited number of prospective studies. However, recent publications from five cohort studies, which together comprise 2663 out of 3463 cases in the published literature for analyses of recreational physical activity, may help resolve this ...
Previous studies have provided limited evidence for a harmful effect of high glycemic index and dietary glycemic load on cancer. The authors analyzed associations among glycemic index, glycemic load, and risk of cancer in women and men in the National Institutes of Health�AARP Diet and Health Study. Published glycemic index values were assigned to 225 foods/food groups. ...
ObjectivesTo describe the baseline demographic data, clinical characteristics and HIV-incidence rates of a cohort at high risk for HIV infection in South Africa as well as the challenges experienced in establishing and maintaining the cohort.Methodology/Principle FindingsBetween August 2004 and May 2005 a cohort of ...
Aromatase inhibitor (AI)-associated arthralgia limits adherence to therapy in breast cancer. The pathophysiology may involve vitamin D status. We wished to establish the optimal concentration of 25(OH)D that prevents or minimizes arthralgia. We used a prospective cohort of 290 women starting AI in whom baseline vitamin D was measured. All received daily ...
Objective To determine if baseline functional health status, as measured by SF-36 (veterans), predicts new onset symptoms or diagnosis of post-traumatic stress disorder among deployed US military personnel with combat exposure.Design Prospective cohort analysis.Setting Millennium Cohort.Participants Combat deployed members who ...
Previous longitudinal cohort studies have suggested an association between baseline depressive symptoms and incident hypertension. We assessed this possible association using data from the Multi-ethnic Study of Atherosclerosis, a population-based prospective cohort study of 6,814 US adults from 4 different racial/ethnic groups. ...
A mechanistic two-stage carcinogenesis model has been applied to model lung-cancer mortality in the largest uranium-miner cohort available. Models with and without smoking action both fit the data well. As smoking information is largely missing from the cohort data, a method has been devised to project this information from a case-control study onto the ...
BackgroundSeveral plausible mechanisms, including fat, iron, heterocyclic amines, and N-nitroso compounds, link meat intake with chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Few studies have investigated these associations.MethodsWe prospectively examined the relationship between meat and associated exposures with CLD mortality (n = 551; not including HCC) and HCC incidence (n = ...
This Issue Brief reports on changes in manufacturers' prescription drug prices during the first three months of 2004 (January through March) for the brand name prescription drugs most widely used by Americans age 50 and over. This report is the first quarterly update in an ongoing study of changes in drug manufacturer prices-that is, manufacturers' prices charged for drugs they sold to ...
BackgroundN-nitroso compounds (NOCs) are found in processed meat and are formed endogenously from intake of nitrite and nitrate. Endogenous NOC formation is antagonized by nitrosation inhibitors in fruit and vegetables (e.g., vitamin C) and promoted by heme in red meat. It has been hypothesized that a diet resulting in high exposure to NOCs increases adult glioma risk.MethodsUsing proportional ...
The epidemiologic evidence for the role of alcohol use in pancreatic cancer development is equivocal. The authors prospectively examined the relation between alcohol use and risk of pancreatic cancer among 470,681 participants who were aged 50�71 years in 1995�1996 in the US National Institutes of Health-AARP Diet and Health Study. The authors identified 1,149 eligible ...
This article evaluates the quality and weight of evidence associated with epidemiologic studies of cancer among occupational cohorts exposed to chloroprene. The focus is on liver, lung, and lymphohematopoietic cancers, which had been increased in early studies. Literature searches identified eight morbidity/mortality studies covering seven chloroprene-exposed ...
OBJECTIVES: To demonstrate the methods of recruitment of a low-income, predominantly African-American study population for the Southern Community Cohort Study (SCCS), a prospective epidemiologic investigation of racial disparities in cancer risk. METHODS: Partnerships with community health centers (CHCs) were formed to reach underserved populations throughout the south. ...
This prospective cohort study compares functional outcomes of bicompartmental knee arthroplasty (BKA) and total knee arthroplasty (TKA) in patients with osteoarthritis (OA) of the patellofemoral and medial compartments. Eligibility criteria included bicompartmental OA with less than grade 2 OA in the lateral compartment and intact cruciate ligaments. Fifty-six patients met ...
Global shifts toward an increasingly Western diet and rises in nutrition-related noncommunicable diseases necessitate systematic examination of dietary change in adults and children. This study longitudinally examined mother and child dietary intakes and their relationship with socioeconomic factors across 4 mutually exclusive cohorts followed over 6- to 7-y time periods ...
Midlife is a period during which ageing-related health problems first emerge. In view of increasing life expectancy, it is of great importance that people in midlife adapt to possible health problems, to be able to lead productive and engaged lives as long as possible. It may be expected that given the better circumstances in which more recent cohorts grew up, they are better ...
The European Union AddNeuroMed program and the US-based Alzheimer Disease Neuroimaging Initiative (ADNI) are two large multi-center initiatives designed to collect and validate biomarker data for Alzheimer's disease (AD). Both initiatives use the same MRI data acquisition scheme. The current study aims to compare and combine magnetic resonance imaging (MRI) data from the two study ...
Baseline level of the cysteinyl leukotriene (CysLT), leukotriene E4 (LTE4), is associated with an increased pain rate in children and adults with sickle cell disease (SCD). To provide additional evidence for a role of CysLTs in the pathogenesis of vaso-occlusion, we tested the hypothesis that LTE4 levels will increase within an individual during painful episodes compared to ...
Objective:To prospectively investigate the relationship between physical activity and Parkinson disease (PD).Methods:We evaluated physical activity in relation to PD among 213,701 participants of the NIH-AARP Diet and Health Study cohort. Physical activities over 4 periods (ages 15-18, 19-29, and 35-39, and in the past 10 years) were noted in 1996-1997, ...
ObjectivePrevious studies have demonstrated a cross-sectional relationship between antiretroviral adherence and HIV virological suppression. We assessed the predictive value of baseline adherence in determining long-term virological failure.DesignWe assessed baseline adherence via an adherence questionnaire between administered to all consenting patients ...
Nevi are important risk markers of melanoma. The study aim was to describe changes in nevi of children using longitudinal data from a population-based cohort. Overview back photography and dermoscopic imaging of up to 4 index back nevi was performed at age 11 years (baseline) and repeated at age 14 years (follow-up). Of 443 children (39% females) imaged at ...
In the Nurses¿ Health Study, a prospective cohort of 83, 779 women aged 30-55 years, who had no history of diabetes, cardiovascular disease or cancer were followed at baseline for development of type 2 diabetes. Vitamin D and calcium intakes from diet and supplements were assessed every 2-4 years t...
Background:The US military is currently involved in large, lengthy, and complex combat operations around the world. Effective military operations require optimal health of deployed service members, and both mental and physical health can be affected by military operations.Methods:Baseline data were collected from 77,047 US service members during 2001�2003 as part of a large, ...
but the proportion of HSV-positive subjects was not different between AD and control groups. These studies were study of elderly subjects. Methods This study was part of the PAQUID (Personnes Agees QUID) research, eight, 10, 13 and 15 years after the baseline visit. Subjects who agreed to participate in the study
To determine dose-response relationships of selenium (Se) intake and markers of Se status in healthy, non-deficient subjects, we conducted a 12 mo. intervention using Se supplements (0, 50, 100 or 200 ug Se [as L-selenomethionine]/d) in a group of 106 men and 155 women. At baseline, this cohort, non...
Description Unsupervised methods: identify and display the distribution of Local Treatment Differences (LTDs) and Local Average Treatment Effects (LATEs) across Clusters of patients chosen so as to be relatively well matched on patient baseline X-covariates. Supervised methods: estimate and validate Propensity Scores and use them to either sub-group or smooth observed patient ...
To estimate failure rates after treatment with benzathine penicillin and to identify determinants of failure that affected outcomes for yaws, we conducted a cohort study of 138 patients; treatment failed in 24 (17.4%). Having low initial titers on Venereal Disease Research Laboratory test and living in a village where yaws baseline incidence was high were ...
The objective of this study was to test whether obesity is a predictor of risk for reporting homebound status. A cohort study was conducted with 21,645 community-dwelling men and women aged 65-97 years. A nutrition screen was administered baseline between 1994-1999 and again 3-4 years later. Univ...
The 12-month prevalence of common mental illnesses in the United States is estimated to be 26 percent, accounting for a large and increasing fraction of all disability in the U.S. general population. The U.S. military is frequently called upon as the firs...
Oakland, California is one of twenty cities across the United States in which parents are participating in a study of Fragile Families and Child Wellbeing. The study follows a new birth cohort of approximately 5,000 children in an effort to learn more abo...
OBJECTIVETo evaluate mechanisms underlying diabetic neuropathy progression using indexes of sural nerve morphometry obtained from two identical randomized, placebo-controlled clinical trials.RESEARCH DESIGN AND METHODSSural nerve myelinated fiber density (MFD), nerve conduction velocities (NCVs), vibration perception thresholds, clinical symptom scores, and a visual analog scale for pain were ...
The effect of overweight and obesity on the risk of fatal disease tends to attenuate with age. To evaluate whether this effect is partly attributable to disease-related weight loss, we examined the prebaseline history of weight loss and diseases associated with weight loss among adults enrolled in a cohort study. We conducted an analysis of 7,855 adult ...
In a cohort of healthy adults (106 M, 155 W) in eastern North Dakota, we assessed the effects of supplementation with L-selenomethionine (SeMet) (0, 50, 100 or 200 mcg selenium [Se]/d for 1yr) on three plasma/serum biomarkers of Se status, which at baseline were: Se, 141.5±23.7 (SD) ng/ml; selenopro...
ObjectiveTo determine the baseline prevalence of cognitive impairment in older men treated with ADT and to assess changes in cognitive performance over time.Methods and resultsThirty-two patients (median age of 71 years, range 51�87) were administrated an extensive neuropsychological testing battery prior to ADT initiation, with 21 (65%) completing post-treatment evaluations ...
BACKGROUND & AIMS: Increased life expectancy in patients with cystic fibrosis (CF) allows better knowledge of non-pulmonary complications like liver disease (CFLD). However, few data have been published in large adult cohorts. The aim of this study was to estimate the prevalence and the prognosis of CFLD in adult CF patients. METHODS: A retrospective analysis of a ...
Previous studies of how parental atopy and exposure to dampness and molds contribute to the risk of asthma have been mainly cross-sectional or prevalent case�control studies, where selection and information bias and temporality constitute problems. We assessed longitudinally the independent and joint effects of parental atopy and exposure to molds in dwellings on the development of asthma in ...
Objective: To describe a survey methodology to evaluate headache characteristics and burden and to present baseline characteristics for the international cohort of survey participants. Methods: A targeted, web-based methodology was used to recruit and survey subjects with migraine in 10 countries. Based on reported symptoms, subjects meeting ICHD-2 ...
Although the etiology of aggression is multifactorial, many studies have associated the Val158Met polymorphism of the COMT with aggression in schizophrenia. This study tests the hypothesis that Met/Met patients display more episodes of aggression and violent behaviour than Val/Val patients in a 6 year follow-up cohort of subjects with schizophrenia in contact with the ...
Diet&Health Stud? NewsPublished for Stud? Participants b? the National Cancer Institute Fall 2008 A Hear?fel? Thanks Dear Participant, The NIH-AARP Diet and Health Study is now in its 14th year and still going strong� thanks to your participation! At
indicating how often on average you have used the amount specified during the past year. Artificially sweetened or plain (1 cup) Sweetened�with fruit or other flavoring (1 cup) Yogurt Ex: AARP Alphabet II
... 1:25 to 2:40 pm Simultaneous Breakout Sessions Breakout Session: Guidance Facilitator: Jenny Scott, Ph.D., Work Group Leader Room B/C ... 2:40 to 2:55 pm Break ...
the "tulip experience." Rene assists in the AARP TAX-AIDE program that provides tax assistance to those several products. He will be heading soon to Guatemala to help an orphanage install a hot water system
... 1 (8) The i=s knife-edW ia positiomed with the light source "On " by moving tba pedestal almg the optic axis until the uaall.st, aarp inp ...
Being overweight during midlife is associated with an increased risk of death, according to a new study conducted by the National Cancer Institute in collaboration with AARP, the nation's leading organization for persons 50-Plus.
Chen H, Huang X, Guo X, Mailman RB, Park Y, Kamel F, Umbach DM, Xu Q, Hollenbeck A, Schatzkin A, Blair A. Smoking duration, intensity, and risk of Parkinson disease.
In order to share some of what we have learned, we present results from two research studies below. Once again, thank you for your continued time and participation in this research.
The US Department of Health and Human Services, and the National Cancer Institute, of which this study is a part, do not disclose, give, sell, or transfer any personal information about your visit unless required by law to do so.
First of all, we would like to thank you for providing important information on your diet and lifestyle in our previous surveys. In addition to cancer research, this information is extremely valuable for understanding the causes of a wide range of chronic diseases in older Americans.
be improved?" Awesome enough! Loved all of them. Excellent. Very informative ... learned stuff I never knew was knowledgeable and helpful. It was awesome! Always different and wonderful. The best exhibit in the convention
In a recent study published in the Journal of the National Cancer Institute, NCI and AARP reported that five or more years of estrogen plus progestin use significantly increased the risk of ovarian cancer for women who have not had a hysterectomy.
... 9:00 � 9:30 am Welcome � Janet Woodcock, MD Deputy Commissioner for ... Burkholder, National Consumers League Lee Hammond, AARP Gary Stein, American Society of ...
DCEG Linkage Newsletter - SCIENTIFIC HIGHLIGHTS Scientific Highlights ALL CANCERS Dairy Food and Calcium Intake Dairy food and calcium intake in relation to total cancer and cancer at individual sites was examined in the NIH-AARP Diet and Health Study.
The NIH-AARP Diet and Health Study investigated physical activity in relation to prostate cancer among white men and African-American men, who have much higher incidence rates. Results are summarized on the web site.
The NIH-AARP Diet and Health Study investigated the association between adiposity and physical activity and pancreatic cancer. A subcohort completed a second questionnaire with information about physical activity and waist and hip circumference. Results are summarized on the web site.
The NIH-AARP Diet and Health Study examined physical activity and body mass index (BMI) in relation to esophageal adenocarcinoma (EADC), gastric cardia adenocarcinoma, and gastric non-cardia adenocarcinoma. Results are summarized on the web site.
By the year 2030, 70 million Americans will be 65 or older (AARP, 2004). Approximately 80 percent of this population will likely be driving themselves. And without appropriate and timely interventions, many are likely to be driving with Alzheimer's diseas...
Northeast Center for Agricultural Health Chamberlain Center of Bassett Healthcare, Fly Creek, NY John May and seasonal (hired) farm workers, ergonomics of labor-intensive crop work, respiratory hazards in dry
The Angelchik Anti-Reflux Prosthesis (AARP) is a surgically implantable C-shaped silicone device used in the treatment of gastroesophageal reflux disease (GERD) which is resistant to medical management. The device is effective in treating hiatus hernia an...
The mailing focuses on the aftermath of the Supreme Court's decision in Cruzan v. Director, Missouri Department of Health, et al., 110 S.Ct. 2841 (1990), as well as providing an update on guardianship legislation.
Purpose: The purpose of this study is to quantify the effect of residential modification on decreasing risk of physical function decline in 2 years. Design: Cohort study using propensity scores method to control for baseline differences between individuals with residential modifications and those without residential modifications. Participants: ...
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BACKGROUND:: The relationship between CD4 T cell counts determined soon after seroconversion with HIV-1 (baseline CD4), nadir CD4, and CD4 levels attained during highly-active antiretroviral therapy (HAART) is unknown. METHODS:: Longitudinal, including baseline (at or soon after HIV diagnosis), intermediate (nadir) and distal (post-HAART) CD4 T cell counts ...
We aimed to evaluate the reasons for, and timing of, treatment changes in a cohort of treatment-na�ve patients initiating non-nucleoside reverse transcriptase inhibitor (NNRTI)-containing highly active antiretroviral therapy (HAART). All 268 patients initiating these regimens between January 1998 and September 2003 were included. Median follow up was 103 weeks. The median ...
Aims. To describe the baseline characteristics of an Australian population-based cohort of rheumatoid arthritis (RA) patients commencing biological therapy. Methods. Descriptive analysis from the Australian Rheumatology Association Database (ARAD). Results. Up to October 2006, there were 681 RA patients taking biologics enrolled in ARAD. ...
BACKGROUNDManagement of degenerative spondylolisthesis with spinal stenosis is controversial. Surgery is widely used, but its effectiveness in comparison with that of nonsurgical treatment has not been demonstrated in controlled trials.METHODSSurgical candidates from 13 centers in 11 U.S. states who had at least 12 weeks of symptoms and image-confirmed degenerative spondylolisthesis were offered ...
BackgroundCurrent approaches for AD prediction are based on biomarkers, which are however of restricted availability in primary care. AD prediction tools for primary care are therefore needed. We present a prediction score based on information that can be obtained in the primary care setting.Methodology/Principal FindingsWe performed a longitudinal cohort study in 3.055 ...
The aim of the study was to evaluate trends in antihyperglycemic agents (AHAs) use in patients with type 2 diabetes mellitus (T2DM) newly initiating extended-release niacin (ERN) compared with other lipid-modifying therapy (LMT). United States administrative-claims data identified adults with T2DM on AHAs who received a new prescription for ERN or another LMT between January 2001 and June 2003 ...
From 1995 through 1996, we mailed 3.5 million questionnaires to current members of the AARP (formally the American Association of Retired Persons), aged 50-71 years, and who resided in one of six states (California, Florida, Pennsylvania, New Jersey, North Carolina, and Louisiana) or in two metropolitan areas (Atlanta, Georgia and Detroit, Michigan). The questionnaire included ...
Objectives. I examined age patterns of mortality differentials associated with body mass because the declining age effect observed in previous comparisons of cross-sectional age groups is susceptible to cohort and period distortions and because previous studies used time since baseline as time at risk, making the evaluation of age-specific mortality ...
ObjectivesTo identify baseline disease-related predictors in patients with early inflammatory polyarthritis (IP) for starting subsequent biological therapy and to determine if patients who failed their first non-biological disease-modifying antirheumatic drug (DMARD) within 6 months were more likely to need biological therapy.MethodsPatients with early IP recruited between ...
IntroductionThe objective of the present study was to examine the association of baseline demographic and clinical characteristics with sequentially obtained measurements of forced vital capacity (FVC), expressed as a percentage of the predicted value, and to identify predictors of the decline rate in FVC over time in the Genetics versus Environment in Scleroderma Outcome ...
BackgroundOsteoporosis and osteoporotic fracture in men are significant public health problems in an aging society. However, information on male osteoporosis remains impressively lacking, especially for Asians. We designed the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study as an ancillary study of a cohort study, the Fujiwara-kyo study, to determine risk factors for ...
Abstract Objective: To examine clinical and economic outcomes associated with angiotensin II receptor blockers (ARB). Methods: Retrospective claims data were analyzed for hypertensive adults with ?1 year follow-up from first ARB claim. Subjects were stratified into four cohorts: olmesartan (OM); valsartan (VAL); losartan (LOS); and irbesartan (IRB), which represented the full ...
PurposeProgression of lower urinary tract symptoms (LUTS) among community dwelling older men is not well described.Materials and MethodsWe evaluated 5,697 participants in MrOS, a prospective cohort study of community dwelling men aged 65 years and older. We characterized LUTS utilizing the American Urological Symptom Index (AUA-SI) at two time points: study entry and 2-year ...
Low circulating folate concentrations lead to elevations of plasma homocysteine. Even mild elevations of plasma homocysteine are associated with significantly increased risk of cardiovascular disease (CVD). Available evidence suggests that poor nutrition contributes to excessive premature CVD mortality in Australian Aboriginal people. The aim of the present study was to examine the effect of a ...
BackgroundWhether there is a temporal relationship between psychological problems and clinical outcomes in patients with diseases of the digestive tract has not been widely researched. Thus, our aims were 1) To observe and compare prospectively clinical outcomes in relation to psychological co-morbidity in patients with inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and chronic ...
BACKGROUND:: Few studies describe temporal trends in pediatric antiretroviral treatment (ART) programs in sub-Saharan Africa. Adult studies show deteriorating patient retention in recent years. We describe temporal trends in baseline characteristics and treatment outcomes amongst ART-na�ve children between 2004-2009 at 30 facilities in four South African provinces. METHODS:: ...
The aim of the present cohort study is the assessment of treatment failure rates in patients on monotherapy with metformin or insulin secretagogues, observed in a routine clinical setting. A cohort of patients without any pharmacological treatment was also observed. A retrospective observational cohort study was performed on a ...
OBJECTIVE The Veterans Affairs Diabetes Trial (VADT) was a randomized, prospective, controlled trial of 1,791 patients with type 2 diabetes to determine whether intensive glycemic control would reduce cardiovascular events compared with standard control. The effect of intensive glycemic control and selected baseline variables on renal outcomes is reported. RESEARCH DESIGN AND ...
Objective:We tested the hypothesis that impaired kidney function in the elderly is associated with a more rapid rate of cognitive decline.Methods:Baseline serum was used to calculate estimated glomerular filtration rate (eGFR), using the Modification of Diet in Renal Disease formula, for 886 elderly without dementia participating in the Rush Memory and Aging Project, a ...
ObjectiveTo evaluate changes in baseline patient characteristics and entry criteria of randomised, controlled studies of tumour necrosis factor alpha (TNF?) inhibitors in rheumatoid arthritis (RA) patients.MethodsA systematic literature review was performed using predefined inclusion criteria to identify randomised, double-blind, controlled trials that evaluated TNF? ...
BACKGROUND AND PURPOSE: Elevated blood pressure (BP) is a risk factor for stroke and dementia, but the effect of BP, and change in BP over time, on white matter hyperintensity volume (WMHV) is not fully understood. Few studies have included Hispanics, who are at greater risk of stroke and dementia than non-Hispanic whites. We examined BP in relation to WMHV in a stroke-free ...
BackgroundEnsuring successful follow-up is essential when conducting a prospective cohort study. Most existing literature reviewing methods to ensure a high response rate is based on experience in developed nations.FindingsWe report our 4-year follow-up success for a national cohort study examining the health transition underway in Thailand. We began the ...
BackgroundMedication side effects are an important cause of morbidity, mortality and costs in older people. The aim of our study was to examine prevalence and risk factors for self-reported medication side effects in an older cohort living independently in the community.MethodsThe Melbourne Longitudinal Study on Healthy Ageing (MELSHA), collected information on those aged 65 ...
To compare the efficacy and safety of Lamivudine (LAM) plus Adefovir dipivoxil (ADV) combination therapy and Entecavir (ETV) monotherapy for chronic hepatitis B patients. 120 patients with chronic hepatitis B managed in a single-centre clinical practice (median 96 weeks) were split into 2 cohorts, one was treated with de-novo combination Lamivudine (100 mg/day) plus Adefovir ...
BACKGROUND: The aim of this study is to assess the impact of combined work and family demands on all-cause sickness absence and to examine variation in this relationship by occupational grade and gender. METHODS: The study sample consists of 13?179 employees of Electricit� de France-Gaz de France (EDF-GDF) who were members of the GAZEL occupational cohort in 1995. Combined ...
ObjectiveThe Clinical Research Center for Depression (CRESCEND) study is a 9-year observational collaborative prospective cohort study for the clinical outcomes in participants with depressive disorders in Korea. In this study, we examined the baseline characteristics of the depressive participants as the hospital-based ...
ABSTRACTBackground: The AIBL study, which commenced in November 2006, is a two-center prospective study of a cohort of 1112 volunteers aged 60+. The cohort includes 211 patients meeting NINCDS-ADRDA criteria for Alzheimer's disease (AD) (180 probable and 31 possible). We aimed to identify factors associated with rapid cognitive decline over 18 months in ...
The authors characterized human immunodeficiency virus (HIV) and hepatitis C virus (HCV) incidence and prospective changes in self-reported risk behavior over 2 years among 1,158 injection drug users (IDUs) recruited in Chennai, India, in 2005-2006. At baseline, HIV prevalence was 25.3%, and HCV prevalence was 54.5%. Seropositive persons with prevalent HIV infection were used ...
Background and objectives: The purpose was to evaluate changes in the left ventricular mass index (LVMi) among anemic chronic kidney disease (CKD) and end-stage renal disease (ESRD) patients treated with recombinant human erythropoietin (EPO).Design, setting, participants, & measurements: A systematic review of the literature, reporting LVMi for patients before and after EPO therapy, was ...
AbstractBackgroundWomen with depressive symptoms may use preventive services less frequently and experience poorer health outcomes. We investigated the association of depressive symptoms with breast and colorectal cancer screening rates and stage of cancer among a cohort of postmenopausal women.MethodsIn The Women's Health Initiative Observational Study, 93,676 women were ...
BackgroundWhile there is considerable research on medical workforce supply trends, there is little research examining the determinants of labour supply decisions for the medical workforce. The "Medicine in Australia: Balancing Employment and Life (MABEL)" study investigates workforce participation patterns and their determinants using a longitudinal survey of Australian doctors. It aims to ...
BackgroundThe Longitudinal Analysis of Nursing Education (LANE) study was initiated in 2002, with the aim of longitudinally examining a wide variety of individual and work-related variables related to psychological and physical health, as well as rates of employee and occupational turnover, and professional development among nursing students in the process of becoming registered nurses and ...
This paper examines HIV risk behavior among HIV-uninfected adults living with people taking antiretroviral therapy (ART) in Uganda. A prospective cohort of 455 HIV-uninfected non-spousal household members of ART patients receiving home-based AIDS care was enrolled. Sexual behavior, HIV risk perceptions, AIDS-related anxiety, and the perception that AIDS is curable were ...
Background/AimsWhile social factors may influence the trajectories of cognitive aging, the influence of spousal characteristics (i.e. health or mental health) on cognitive decline has received little attention. This study examined the influence of baseline depressive symptoms in one spouse on cognitive functioning in the other.MethodsWe conducted a longitudinal study of 279 ...
There is controversy on the validity of binary end points used in irritable bowel syndrome (IBS) clinical trials. In a usual-care observational study, baseline severity influenced the response measured as satisfactory relief. This editorial reviews the observations from a non-pharmacological study to assess the effect of baseline severity on the ...
AbstractBackgroundBaseline characteristics from the adult cohort of a randomized controlled trial comparing sensor-augmented pump (SAP) and multiple daily injection (MDI) therapy were analyzed for significant relationships with ?0.5% A1C change at 1 year of therapy without incidence of severe hypoglycemia (defined as A1C ...
Objective To investigate the hypothesis that plasma leptin may predict adiposity changes.Design A population-based cohort study.Setting Fleurbaix and Laventie, in the north of France.Subjects 1175 subjects participated, of whom 946 completed measurements at baseline (1999) and follow-up (2001). After excluding 64 subjects obese at ...
Objective To describe new onset and persistence of self reported post-traumatic stress disorder symptoms in a large population based military cohort, many of whom were deployed in support of the wars in Iraq and Afghanistan.Design Prospective cohort analysis.Setting and participants Survey enrolment data from the millennium cohort ...
In this article scenarios have been developed, which simulate screening effects in ecological and cohort studies of thyroid cancer incidence among Ukrainians, whose thyroids have been exposed to (131)I in the aftermath of the Chernobyl accident. If possible, the scenarios were based on directly observed data, such as the population size, dose distributions and thyroid cancer ...
ObjectiveThe aim of the study was to collect pilot data on response rates to a follow-up postal questionnaire in a cohort of American Indians living in the Southwestern United States. We tested the effect of questionnaire length on response.MethodsCohort members were American Indian adults aged 18 and over who completed the baseline ...
BackgroundA major barrier to addressing the problem of transport injury in low to middle-income countries is the lack of information regarding the incidence of traffic crashes and the demographic, behavioural and socio-economic determinants of crash-related injury. This study aimed to determine the baseline frequency and distribution of transport injury and the prevalence of ...
Adiponectin is an adipose-derived protein with beneficial metabolic effects. Low adiponectin is associated with obesity and related diseases. Significant weight loss increases adiponectin, reducing disease risk. This study compared the effects of two weight-loss diets with different macronutrient compositions on adiponectin. Eighty-one obese women in two cohorts were ...
Metabolic syndrome (MetS) constitutes a worldwide epidemic burst accounting for billions of cardiovascular disease events and deaths. The genetic basis of MetS is largely unknown. The rs11646213 T ? A polymorphism maps at 16q23.3 upstream of the CDH13 gene codifying for cadherin-13 (also known as T-cadherin or H-cadherin), which is considered a vascular adiponectin receptor. This and other ...
The association between many psychosocial factors and risk of suicide was examined. A cohort was conducted over 14 years of follow up among the general population (15,597 people) in Japan. A baseline survey of psychosocial characteristics was conducted by self-administrated questionnaire. The relative risks of occasional emotional stress, difficulty ...
The prevalence of childhood obesity is of great public health concern. A social ecological framework that is transdisciplinary and multilevel by nature is recognized as the most promising approach for studying this problem. The purpose of this paper is to describe longitudinal research using a social ecological framework to study the etiology of childhood obesity. Individual and contextual factors ...
