vapor snakes in. CO-Ol solutions. . AB38. Goldstone Tracking Station ..... statistics in determination. . AB38. determination with large antennas. ...
NASA Website
We report on the determination of a high quality ab initiu potential energy surface (PES) and dipole
NASA Technical Reports Server (NTRS)
Two approaches for directly computing a molecular heat of formation based on sophisticated ab initio
... A check test of the Mast AB-577 was ... Functional testing was conducted in temperatures ranging from -5 F ... The purpose of the test was to determine if ...
DTIC Science & Technology
... Title : AB Initio Study of the Electronic Magnetic Circular Dichroism ... functions are determined using as initio quantum chemical techniques including ...
Eight different light vehicles, each with a different antilock braking system (ABS), were tested to determine how the ABS influenced vehicle stopping distance, stability and control on various road surfaces. An epoxy coated surface, which when wet has a v...
National Technical Information Service (NTIS)
Rabbit anti-idiotypic antibodies (alpha Id Ab) were prepared against five murine monoclonal antibodies (mAb) specific for the rabies virus glycoprotein. Four of the mAb were directed against three known, type-specific, neutralizing sites on the glycoprotein, and the other mAb was directed against a topographically ...
PubMed Central
Anti-Aspergillus spp. antibody (Ab) levels of seven mating pairs of captive African penguins (Spheniscus demersus) and the maternal Ab levels of their embryonated and unembryonated eggs were determined by ELISA. The egg Ab levels were significantly higher than the Ab levels of their female or ...
PubMed
The results of an ab initio determination of the rate of constant for H+H/sub 2/CO are presented. (AIP)
Energy Citations Database
... ONE DECADE OF AB/D CONVERTER SERVES AS PILOT STUDY TO DETERMINE STATE OF THE ART AND CONTRACTOR CAPABILITY IN ...
... the potential energy surface provided by modern electronic structure ... screening approach, to determine the equilibrium geometry and composition ...
Azo-derivatives of chromotropic acid and azo-dyes of the stilbene series were studies as possible reagents for photometric determination of aminoglycoside antibiotics (AB) in biological materials. The complex of Pr3+ with stilbazochrome-P (Sch-P) proved to be the best precipitant of AB. P (Sch-P) with Pr3+ and AB ...
Processing of odor mixtures by neonates is weakly understood. Previous studies showed that a binary mixture of ethyl isobutyrate/ethyl maltol (odorants A/B) blends in newborn rabbits at the 30/70 ratio: Pups would perceive a configural odor in addition to the components' odors. Here, we investigated whether the emergence of this additional odor in AB is ...
Jun 16, 2011 ... Stockholm, Sweden : STFI-Packforst AB, 2003: pages 207-211 ... literature were determined using test specimens with rectilinear geometry. ...
Treesearch
Ab initio calculations are carried out to determine ?? (true), the first-order contribution to the spin-rotation constant, ??, for the X2? ground states of ...
The number of ab initio molecular electronic calculations has increased dramatically in the last few years. Both the practitioners and other interested students of the results of the calculations have found it increasingly difficult to determine the prese...
The detailed molecular structure of methyl phosphonate, the simplest phosphorus ester, was determined by ab initio quantum-chemical calculations in a variety of basis sets. Computed properties include the optimized structure, dipole moment, number and rel...
Dehydrogenation of ammonia borane (AB) and methylamine-borane (MeAB) is catalyzed efficiently by the iridium pincer complex (η3-1,3-(OPtBu2)2C6H3)Ir(H)2 (1). With MeAB and with MeAB/AB mixtures, rapid release of one equivalent of H2 is observed to yield soluble oligomeric products at rates similar to those ...
This report describes the characterisation of a monoclonal antibody (mAb), AB6, which recognises specifically a cluster of canine leukocyte surface molecules. The immunogen used for obtaining the AB6 mAb was a lysate of canine peripheral blood mononuclear cells (PBMC). This novel mAb belongs to ...
Ten Speckle Interferometric observations of the triple system Algol are combined with spectroscopic orbital parameters for a determination of orbital inclination, the stellar masses and the distance of the system. The results confirm that the long period system Algol AB-C is nearly coplanar with the eclipsing binary Algol AB. The ...
NASA Astrophysics Data System (ADS)
3-aminobenzamide (3AB) is a potent inhibitor of poly(ADP-ribose) synthesis and has been reported to inhibit DNA repair. Inhibition of poly(ADP-ribose) synthesis by 3AB results in a potentiation of the cytotoxic effects of alkylating agents and synergistically increases the frequency of sister chromatid exchanges (SCEs) induced in Chinese hamster ovary ...
Two genes were identified in Bacillus thuringiensis Berliner (Bt) that code for the proteins that comprise a Cry34Ab1/Cry35Ab1 binary insecticidal crystal protein. Maize, Zea mays L., plants have been transformed to express the Cry34Ab1/Cry35Ab1 proteins, and as a result, these plants are resistant to attack by ...
Research on the transmission of infectious diseases amongst the human population at fine scales is limited. At this level, the dynamics of humans are determined by their social activities and the physical condition of the environment. Raster space AB (activity bundle) simulation is a method to simulate humans' contacts within a space under the framework of ...
3-Aminobenzamide (3-AB), an inhibitor of poly(ADP-ribosylation), is lethal to human fibroblasts with damaged DNA. Its cytotoxicity was determined relative to a number of factors including the types of lesions, the kinetics of repair, and the availability of alternative repair systems. A variety of alkylating agent, UV or gamma irradiation, or ...
A committee of the College of American Pathologists has proposed that the diagnosis of asbestosis requires fibrosis in respiratory bronchiolar walls and the presence of asbestos bodies (ABs) in tissue sections. To determine whether histologic ABs reliably reflect asbestos fiber concentrations in asbestosis, we compared the ...
overexpression of Ab resulted in decreased den- field. All statistical analyses were done using Student's t tests-of-function mutations in the dendritic morphogenesis. For instance, Sequoia, a Tram-abrupt (ab) gene that increased. Ab encodes an evolution- plays a role in both cell fate determination and ...
E-print Network
This research is mainly devoted to state to state studies of reactions of the form A + BC = AB + C, AB + CD = ABC + D and A + BCD = AB + CD in which A,B,C,D are atoms. Some of the work has been development of new techniques for the determination of state ...
A global search for possible LiF cluster structures is performed up to (LiF)(8). The method is based on simulated annealing, where all the energies are evaluated on the ab initio level. In addition, the threshold algorithm is employed to determine the energy barriers for the transitions among these structures, for the cluster (LiF)(4), again on the ...
The nuclear magnetic resonance chemical shift is one of the most powerful properties available for structure determination at the molecular level. A review of advances made in the ab initio calculation of chemical shielding during the past five years is presented. Specifically, progress in the areas including the effects of an unpaired electron, electron ...
We have studied structural and dynamical properties of Mg2Sn by employing an ab-initio pseudopotential method and a linear response scheme, within the generalised gradient approximation. The calculated lattice constant, bulk modulus and pressure derivative of bulk modulus are in agreement with previous ab-initio calculations and available experimental ...
We have determined the fluorescence characteristics of two long wavelength dyes, albumin blue 633 (AB633) and 670 (AB670), in plasma and blood to evaluate the possibility of making direct fluorescence sensing measurements in blood. Using binding and lifetime measurements we were also able to show that these dyes bind selectively to ...
There is evidence that the T-cell antigen receptor is immunoglobulin-related and that normal human T cells express surface determinants which cross-react with chicken anti-F(ab')2, anti-alpha and anti-mu antibodies. Surface marker study of six neoplastic human T cell lines suggested that F(ab')2- and mu-cross-reactive ...
We produced a monoclonal antibody (mAb) as a probe for detection of Tri a Bd 27K, a major wheat allergen. The mAb recognized the allergen purified from wheat flour, and the epitope on the allergen to the mAb was determined to be amino acid sequence (154)VPWVVVDGKPL(164) of Tri a Bd 27K. Of the amino acid residues ...
tested for Hu, Ri, Yo, CV2/CRMP5, Tr and amphiphysin antibodies. The presence of[4] CV2/CRMP5-Ab-Whitney test for quantitative data. ** available in the data bases for only 69 patients with Hu-Ab and for all-Hu antibodies (Hu-Ab) and anti-CV2/CRMP5 antibodies (CV2/CRMP5-Ab) have been identified in association
Monoclonal antibodies (mAbs) are attractive vehicle so far targeting radiation to tumors because of their ability to react specifically with molecular determinants that are either uniquely expressed or over expressed on cancer cells. However, the clinical impact of labeled mAb is hampered by loss of the label from the ...
Cancer.gov
Two strains of necrotrophic Alternaria brassicicola, Ab40857 and Ab42464, are virulent on Korean cabbage and several wild types of Arabidopsis thaliana. Interaction between Ab42464 and Col-0 was compatible, whereas interaction between Ab40857 and Col-0 was incompatible. The loss of defense, no death (dnd) 1 ...
Chiral determinism and the origin of translation ... Roadmap Goal 5: Understand the evolutionary mechanisms and environmental limits of life ...
naphthalene and tetralin using DSC measurements and heat of solutions determined by microcalorimetry
Ab initio molecular orbital theory has been used to determine the equilibrium geometries, rotational
ABS>The radiochemical degradation of alpha -aminobutyric acid was studied. The main products of radiolysis were determined and the mechanism of their production was derived. (auth)
-determination system (e.g., accord- mosome (Singer et al. 2002), and in the planarian Schmidtea polychroa
The broad goal of this research is to address the problem of understanding the propagation of light in the ocean and its ramifications for underwater imaging. In particular, we are interested in developing inversion algorithms for determining the total ab...
powder XRD for fine particle analysis, and single crystal. XRD for coarse materials analysis and ab-initio structure determination. Hybrid-XRD design will ...
... phosphorus species have not been previously determined and were estimated from the results of ab initio quantum chemical calculations available ...
... Validation Protocol for the Determination of Identity for the ... the Analytical Method for Quantifying F(ab)2 ... M-CB-001 �SOP for the Development of Immunization ...
Center for Biologics Evaluation and Research (CBER)
... 45, 65, 85, 104, and 147 MHz: and one between Sondrestrom AB and Narsarsuaq (NSSQ), operating at 45, 65, 85, and 104 MHz. ... 39 Page 45. ...
... mobility as an indicator of viability in the � 50 µm size class, this study investigated the addition of four stains: neutral red (NR), aniline blue (AB ...
The objective of this research was to investigate fundamental aspects of the fracture and deformation behavior of ordered intermetallic aerospace alloys on the basis of the ab-initio determination of the parameters needed for further (1) model theoretical...
... the PRMD code - in Step 1- will be validated and further studied using ab initio methods to determine kinetic and thermodynamic properties of the ...
Identifies class a, ab, b, and c amplifiers from their characteristic curves. Compares their efficiency and fidelity. Demonstrates how the bias and magnitude of the input signal determines the class of operation.
Spectroscopic constants and dissociation energies for the ground states of N2, O2, and F2 determined
For some simple, but nontrivial molecular systems, the interaction potentials are now well determined from ab initio electronic structure calculations ...
Page 1. OCT. 30, 1997 MEMORANDUM SUBJECT: Determining the Need for Tolerances in Livestock Commodities. FROM ...
EPA Pesticide Factsheets
The unimolecular decay lifetimes of several vibrational states of HN2 are determined on the basis of
Recent reports have revealed that detonation nanodiamonds (NDs) can serve as efficient, biocompatible, and versatile drug delivery platforms. Consequently, further investigations exploring additional therapeutic applications are warranted. Current limitations associated with the non-specific nature of intravenous drugs limit the potential of certain pharmacological agents. One such treatment that ...
The purpose of these studies was to determine if prostate carcinoma (PC) and cutaneous T-cell lymphoma (CTCL) could be detected using the In-lll- MoAbs described in this paper. Murine IgG MoAbs were developed against prostatic acid phosphatase (PAP) and to an antigen present on human T-cells. The MoAbs were labeled ...
The protective anti-beta abortus monoclonal antibody ISS/32 (Ab1) was used as an immunogen to induce anti-idiotypic antibodies (Ab2) in rabbits. The purpose was to produce and characterize anti-idiotypic antibodies that share conformational similarity with the corresponding bacterial epitope recognized by Ab1. The rabbit ...
The K88ab adhesin operon of Escherichia coli encodes for a fimbrial protein (the K88ab adhesin) which is involved in colonization of the porcine intestine. We characterized a structural gene (gene A) which is part of the K88ab adhesin operon and codes for an as yet unidentified polypeptide (pA). A mutation in gene A resulted in ...
The subtilase cytotoxin (SubAB) is an AB5 toxin described in certain Shiga toxin (Stx)-producing Escherichia coli (STEC) strains that usually lack the locus for enterocyte effacement (LEE). We report for the first time the production of SubAB by two Stx-negative E. coli strains, isolated from unrelated cases of ...
Through the use of a molecular pseudopotential method, we determine the a approximate magnitudes of errors that result when electron affinity determinations of polar negative ions are made through ab initio calculations in which the use of a given basis set yields inappropriate values for permanent and induced dipole moments of the ...
We investigate atomistic mechanisms governing hydrogen release and uptake processes in ammonia borane (AB) within the framework of the density functional theory. In order to determine the most favorable pathways for the thermal inter-conversion between AB and polyaminoborane plus H(2), we calculate potential energy surfaces for the ...
We investigate atomistic mechanisms governing hydrogen release and uptake processes in ammonia borane (AB) within the framework of the density functional theory. In order to determine the most favorable pathways for the thermal inter-conversion between AB and polyaminoborane plus H2, we calculate potential energy surfaces for the ...
Controlling the covalent bonding of antibodies onto functionalized carbon nanotubes is a key step in the design and preparation of nanotube-based conjugates for targeting cancer cells. For this purpose, an anti-MUC1 antibody (Ab) is linked to both multi-walled (MWCNTs) and double-walled carbon nanotubes (DWCNTs) using different synthetic strategies. The presence of the ...
Anti-human serum albumin antibody (Ab) was reacted with cyclic DTPA dianhydride (cDTPAA) at various cDTPAA/Ab molar ratios between 1 and 40. Using a carrier In titration method for DTPA and DTPA-antibody conjugate (Ab-DTPA). The authors determined that the above reactions produced between 0.1 and 11 DTPA molecules ...
Two monoclonal antibodies (mAb 124D1 and mAb 129C4) raised against the purified alpha subunit were noninhibitory in reactions directed by lacP/sup +/. Reconstitution of dissociated core polymerase in the presence of mAb 129C4 resulted in only a 5% recovery of enzyme activity whereas mAb 124D1 was without ...
Murine monoclonal antibodies (mAb) produced against native human thyroid peroxidase (TPO) are powerful tools for analyzing the autoantibody (Aab) epitopes on TPO. Binding sites of thirteen mAbs cover all or most antigenic regions on TPO. We determined the competition between Aabs from 75 AITD patients and 13 mAbs ...
Zona pellucida glycoproteins play an important role in fertilization. In this study, attempts have been made to identify and define epitopes of monoclonal antibodies (mAbs) possessing contraceptive efficacy in vitro. The porcine zona glycoprotein pZPC, a homologue of mouse/human ZP3, was reduced and alkylated and subsequently digested with trypsin. Reverse-phase HPLC of the ...
To facilitate a detailed investigation of pinniped lymphoid organs, 30 monoclonal antibodies (mAb) as well as eight polyclonal antibodies (pAb) of different species specificities directed against cell antigens of the hematopoietic system were tested for immunohistochemical cross-reactivity on formalin-fixed, paraffin wax-embedded tissues of harbor seals ...
Human anti-murine antibody (HAMA) response is a serious problem in the repeated infusion of murine monoclonal antibodies (MoAbs). HAMA positive sera were obtained from seven patients with colorectal cancer, pancreas cancer, malignant melanoma or myocardial infarction who had previously received radiolabelled MoAbs. The nature of HAMA was analysed using ...
GAD65Ab and ICA512Ab are strongly associated with insulin-dependent (Type 1) diabetes mellitus. A novel, simple radio-antigen binding assay with microSepharose conjugated with monoclonal antibodies specific for human immunoglobulin light chains was developed to provide diagnostic sensitivity and specificity of GAD65Ab and ...
The functional relevance of autoantibodies (Abs) against cardiac myosin (CM) in clinical idiopathic dilated cardiomyopathy (DCM) remains controversial. The study sought to determine effects of human Abs affinity-purified (AF) by immunoaffinity column chromotography on excitation-contraction coupling in isolated myocytes. Effects of ...
Several monoclonal antibodies (McAbs) against pili of Bacteroides nodosus were examined to determine their reactivity with 11 different serotypes. One McAb was identified by enzyme-linked immunosorbent assay (ELISA) analysis that bound to nine of the 11 serotypes and another that bound to the remaining two serotypes tested. In ...
Enzyme linked immunosorbent assay (ELISA) methods for quantitatively determining the level of PDGF-BB and PDGF-AB or PDGF-AA and PDGF-AB present in a human's bodily fluids, tissue extracts, or a fluid contacting humans cells in culture, are disclosed.
The vibrational frequencies of the electronic ground state of resorcinol have been determined via laser-induced dispersed fluorescence spectroscopy. An assignment based on comparison with ab initio calculations on the MP2 and B3LYP (6-311 G (d,p)) level is presented.
We use atomic pseudopotential s-orbital radii and Pauling electronegativity chi to distinguish between four types of crystal structures (ZnS, NaCl, CsCl, and MnP or NiAs) for AB compounds. By relating chi to the s-orbital radii, an even simpler scheme results, indicating the important role of pseudopotential s-orbital radii for structural determination.
The recent literature on the determination of minimum energy conformations by ab initio quantum mechanical techniques is reviewed. The availability of computer-coded analytical first and second derivatives of the Hartree-Fock energy makes possible calculations that will be of significant assistance in structure determination of ...
We use ab initio crystalline calculations to explore the role of iodine in determining the properties of 1,4-diiodobenzene. The results strongly suggest that the large halogen is an important or perhaps the dominant determinant of the ability of diiodobenzene to transport holes. We conjecture that the high mobility of diiodobenzene is ...
...combinations: plan ABC, plans AB and C, plans AC and...Determination of plans in testing group for average benefit...basis. The plans in the testing group used to determine...a single plan (Plan AB). The plans in the testing group used to...
Code of Federal Regulations, 2011
3-Aminobenzamide (3AB) is a potent inhibitor of poly(ADP-ribose) synthesis and has been reported to inhibit DNA repair. Inhibition of poly(ADP-ribose) synthesis by 3AB results in a potentiation of the cytotoxic effects of alkylating agents and synergistically increases the frequency of sister chromatid exchanges (SCEs) induced in Chinese hamster ovary ...
This paper reports for the first time that under ammonia atmosphere, ammonia borane (AB) reversibly absorbs up to at least 6 equiv of NH(3), forming liquid AB(NH(3))(n) (n = 1-6) complexes at 0 �C. Reasonable structures for AB(NH(3))(n) were identified via density functional theory calculations, which indicate that the strong ...
We report the first direct observation of the oxygen-isotope ((16)O/(18)O) effect on the in-plane penetration depth lambda(ab) in a nearly optimally doped YBa(2)Cu(3)O(7-delta) film using the novel low-energy muon-spin rotation technique. Spin-polarized low-energy muons are implanted in the film at a known depth z beneath the surface and process in the local magnetic field ...
Asbestos body (AB) concentrations in bronchoalveolar lavage samples of 15 brake lining (BL) workers exposed only to chrysotile have been determined and compared with those from 44 asbestos cement (AC) workers extensively exposed to amphiboles. The mean AB concentrations (263 +/- 802 and 842 +/- 2086 AB/ml ...
ABS>Quinalizarin methods are reported for determining boron in U-Zr alloys, uranium oxides, and aluminum base materials. (W.L.H.)
A highly sensitive and selective spectrophotometric method was developed for the determination of thorium in xenotime. The method is based on the green water-soluble complex formed when thorium and arsenazo III react in strong hydrochloric acid medium (ab...
The results of investigations in the determining of the moisture of stream at the outlet of a cyclone machine as depends on the steam load in the interval of pressure 9--33 abs. atm. are presented. An empirical formula is derived for determining the moist...
ABS>Residual chlorine present in silica-supported rhodium catalysts, prepared from rhodium trichloride, has been determined by neutron activation analysis and gamma spectrometry. (auth)
BackgroundTo investigate whether Stiff-person syndrome (SPS) and cerebellar ataxia (CA) are associated with distinct GAD65-Ab epitope specificities and neuronal effects.MethodsPurified GAD65-Ab from neurological patients and monoclonal GAD65-Ab with distinct epitope specificities (b78 and b96.11) were administered in vivo to rat ...
The authors quantitatively study the effect of growth-induced reduction of long range structural order on the superconducting transition in epitaxial YBa{sub 2}Cu{sub 3}O{sub 6.9} films. The corresponding reduction of structural coherence length r{sub c} is determined from the width of X-ray diffraction rocking curves. {Tc} measurements in the films give evidence for the ...
Cat and dog albumins from commercial extracts were used to produce monoclonal antibodies (MoAb). Anti-cat albumin MoAb recognized both cat and dog albumin equally, as did anti-dog albumin MoAb; this confirms cross-reactivity between cat and dog. The MoAb were separated into two groups according to their epitopic ...
We perform ab initio molecular dynamics simulations to study the dissociation of NaCl in water. The potential of mean force (PMF) between the two ions is determined using the constrained-force method. The simulation windows corresponding to the contact and solvent-separated minima, and the transition state in between, are further analyzed to ...
The star HD 193322 is a remarkable multiple system of massive stars that lies at the heart of the cluster Collinder 419. Here we report on new spectroscopic observations and radial velocities of the narrow-lined component Ab1 which we use to determine its orbital motion around a close companion Ab2 (P = 312 days) and around a distant ...
Precision binding of monoclonal antibodies (mAbs) to biological targets, their relative clinical success, and expansion of indications following initial approval, are distinctive clinical features. The relatively high cost of mAbs, together with the absence of a regulatory pathway to generics, stand out as distinctive economic features. Based on both ...
A monoclonal heterohybridoma cell line (B11-12) was developed by fusing EBV-transformed lymphocytes from a patient with hyper-IgE syndrome and SHM-D33 heteromyeloma cells. The resultant heterohybridoma secreted only human lambda L chains exhibiting specific binding to mouse monoclonal Ab to human IgE (mAb-algE). B11-12 bound to four separate ...
The characteristics of thyroglobulin (Tg) autoantibodies in Obese strain (OS) chickens with thyroiditis have been defined and compared with those of polyclonal antibodies to chicken Tg produced by immunizing normal chickens and a rabbit, and with mouse monoclonal antibodies (MoAb) to chicken Tg. Chicken Tg autoantibodies (aAb), when tested against Tg from ...
In this work we analysed the modulation of the antibody response to Echinococcus granulosus antigens via anti-idiotype (Ab2) administration. In a first set of experiments, we determined the antibody response to hydatid cyst fluid antigen (HCFA) of mice immunized with Ab2. Results showed that Ab2 elicited anti-HCFA ...
A method for determining the ratio of DTPA molecules attached per molecule of Ab was developed and used to examine the immunoreactivity of different Abs as a function of the amount of incorporated DTPA. The bicyclic anhydride of DTPA(2-C-14)acetic acid (BADTPA-C-14) was synthesized by reacting DTPA(2-C-14)acetic acid (1mCi/mmo1) and ...
In this work, we present a study on water acetonitrile (AN) mixtures by molecular dynamics ab initio and X-ray diffraction techniques. Comparison of the experimental total G(r) functions of the mixtures with the results of molecular dynamics simulation shows an overall good agreement. The properties of hydrogen bonded clusters (water clusters, and water AN clusters) in these ...
Structural and energetic properties of small, deceptively simple anionic clusters of lithium, Li(n)(-), n = 3-7, were determined using a combination of anion photoelectron spectroscopy and ab initio calculations. The most stable isomers of each of these anions, the ones most likely to contribute to the photoelectron spectra, were found using the gradient ...
Structural and energetic properties of small, deceptively simple anionic clusters of lithium, Lin-, n = 3-7, were determined using a combination of anion photoelectron spectroscopy and ab initio calculations. The most stable isomers of each of these anions, the ones most likely to contribute to the photoelectron spectra, were found using the gradient ...
produced a phage multilayer hav- ing a coverage equivalent to 6.5 close-packed monolay- ers of the virus with exposure to an antibody (p-Ab) known to bind the phage particles with high affinity. Bound p-Ab was removed of p-Ab enabling the determination that an average of 140 binding sites are available per M13 ...
Delayed and weak virus neutralizing antibody (nAb) responses represent a hallmark correlating not only with the establishment of persistent infection but also with unsuccessful vaccine development. Using a reverse genetic approach, we evaluated possible underlying mechanisms in 2 widely studied viral infection models. Swapping the glycoproteins (GPs) of lymphocytic ...
The capacity of immune complexes to augment antibody (Ab) responses is well established. The enhancing effects of immune complexes have been attributed mainly to Fc-mediated adjuvant activity, while the ability of Abs to induce antigenic alterations of specific epitopes as a result of immune complex formation have been less well studied. Previously we have ...
In order to study the effect of costimulatory signals on T helper type 2 (Th2) cytokine production, monoclonal antibodies (mAb) against cell adhesion molecules (CAM) were added to cells in culture obtained from the lungs of Toxocara canis (Tc)-infected mice followed by the determination of interleukin-5 (IL-5) and IL-4 in the supernatants of the culture. ...
IntroductionReactivation of hepatitis B virus (HBV) infection in patients with past infection has been described in 5% to 10% of individuals undergoing immunosuppressive therapies. No data are available to date on the outcome of patients treated by tumour necrosis factor-alpha (TNF?) inhibitors for chronic arthritis with a serological pattern of past HBV infection. The aim of our study was to ...
This paper presents a wheel slip control via sliding mode controller for a new anti-lock brake system (ABS) of a passenger vehicle using electrorheological (ER) valve pressure modulator. The principal design parameters of the ER valves and hydraulic booster are appropriately determined by considering braking pressure variation during ...
We have measured the difference in the density of states (dos) in Bi2Sr2Ca1Cu2O8 (2212) between the c-axis and the ab-plane in our earlier experiments. Anisotropic properties within the ab-plane are not well established experimentally yet. We have performed tunneling experiments in three different directions within the ab-plane on the ...
We determined the seroprevalence of hepatitis A virus antibodies (HAV Ab) among 296 Egyptian children aged 2.5-18 years of different social classes to ascertain whether to give HAV vaccine early in life or to leave children to acquire natural immunity. Overall 61.4% were seropositive for HAV Ab. There was a significant increase in the ...
The study of the ductile B2, CsCl-type AB intermetallic compounds has been expanded over the past few years in order to determine the underlying principles that account for their ductility. Using a global semi-empirical alloy theory approach together with first-principles band theory, we show that absence of d-band electrons near the Fermi level accounts ...
The epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor involved in the proliferation and survival of cancer cells. EGFR is the first molecular target against which monoclonal antibodies (mAb) have been developed for cancer therapy. Here we review the mechanisms underlying the effects of EGFR-specific mAb in cancer therapy. ...
Assembly Bill (AB) 1402 authorized California's school districts to enter into design-build contracts for projects with design and construction costs exceeding $10 million. These guidelines are intended to accomplish the following purposes: (1) inform school districts of the design-build process under AB 1402; (2) help school districts to ...
ERIC Educational Resources Information Center
An enzyme desulfonating anionic alkyl benzene sulfonate (ABS) surfactants was isolated from Pseudomonas alcaligenes TR and purified. The physicochemical and catalytic characteristics of the enzyme were studied. The kinetic constants of ABS desulfonation were determined and shown to depend on the length of a hydrocarbon radical. The ...
The phonon dispersion relations of bulk hexagonal boron nitride have been determined from inelastic x-ray scattering measurements and analyzed by ab initio calculations. Experimental data and calculations show an outstanding agreement and reconcile the controversies raised by recent experimental data obtained by electron-energy loss spectroscopy and ...
The phytotoxin thaxtomin, produced by plant pathogenic Streptomyces species, is a pathogenicity determinant for common scab. In this study a SYBR Green quantitative real-time PCR assay using primers targeted on the txtAB operon of Streptomyces was developed to quantify pathogenic bacterial populati...
Technology Transfer Automated Retrieval System (TEKTRAN)
A new method for specific antibody production was developed using antibody (Ab)-pesticide complex as a unique immunogen. Parathion (PA) was the targeted pesticide, and rabbit polyclonal antibody (Pab) and mouse monoclonal antibody (Mab) were used as carrier proteins. The Ab-PA complexes were genera...
Fully-microscopic No-core Shell Model (NCSM) calculations of all stable s and p shell nuclei are used to determine realistic NN interaction JISP16 describing not only the two-nucleon data but the binding energies and spectra of nuclei with A {le} 16 as well. The JISP16 interaction, providing rapid convergence of the NCSM calculations, is obtained in an ab ...
-dependent reduction of benzyl viologen and AQDS reduction were determined in a reaction buffer containing Tris/HCl (pH were perturbed in the `acetate-adapted' SfrAB-null strain. Membrane and soluble fractions prepared from as the electron acceptor and a limiting concentration of acetate (5 mM) as electron donor and carbon source
The susceptibility of 18 field populations of the sugarcane borer, Diatraea saccharalis (F.) to two sources of Bacillus thuringiensis Cry1Ab protein was determined by laboratory bioassays. Fifteen of the 18 field populations were collected from seven locations across Louisiana and the other 3 popula...
The use of damping functions to correct the multipole expansion at short-range is explored. Damping functions for the terms in the multipole expansion can be determined ab initio as a linear combination of analytic functions of the separation between sites, but there are additional short-range terms that have different angular dependence. The approach ...
For the development of HER2/neu mimicking anti-idiotype antibodies (Ab2s), groups of female BALD/c mice were immunized with three sets of monoclonal antibodies (Ab1), designated 520C9, 741F8 and 454C11, directed at distinct antigenic determinants of HER2/...
A study was made of the immunotherapeutic effect of short ragweed pollen extracts prepared by an 8-minute extraction of pollen and a 24-hour extraction. The extracts were analyzed for their content of allergens E, Ra3, Ra5 (A&B forms) and Ra6 (A&B forms)....
This report contains a method for determining the van der Waals and acid-base contributions to the overall (sup 31)P chemical shifts ((Delta)(delta)(sup d) and (Delta)(delta)(sup ab)) and to the Acceptor Numbers (AN(sup d) and AN(sup ab)) of the Meyer and...
This report contains a method for determining the van der Waals and acid-base contributions to the overall {sup 31}P chemical shifts ({Delta}{delta}{sup d} and {Delta}{delta}{sup ab}) and to the Acceptor Numbers (AN{sup d} and AN{sup ab}) of the Meyer and Gutmann two-component systems, and to illustrate the method with experimental ...
DOE Information Bridge
Vibrational frequency shift upon the 1 : 1 acetone-iodine complex formation was determined from geometries optimized at the SCF (Self Consistent Field) and MP2 (Moeller-Plesset Second Order Perturbation) levels using the ab initio MO (Molecular Orbital) t...
Ab initio molecular orbital theory has been used to examine the kinetics and mechanism for the reaction of chlorine atoms with methyl formate. From the ab initio parameters, the room-temperature rate constant is calculated and found to be in reasonable agreement with the experimental determination. It is found that 90% of the reaction ...
Electron energy-loss spectroscopy has been shown to be a powerful tool to determine the chemistry and the electronic structure at grain boundaries by analyzing the energy loss near edge structure (ELNES). This paper describes the ability of ab-initio density of state calculations to perform detailed quantitative analysis at interfaces.
Ab initio study of ferroelectricity in BaTiO3 nanowires G. Pilania, S. P. Alpay, and R. Ramprasad for axial, trans- verse, and toroidal ferroelectric polarization instabilities in these nanowires have been for ferroelectricity via polarization along the nanowire axis is determined to be 12 �, regardless of the stoichiometry
We calculate ab initio values of tight-binding parameters for the f- electron metal Ce and various phases of Si, from local-density functional one-electron Hamiltonian and overlap matrix elements. Our approach allows us to unambiguously test the validity of the common minimal basis and two-center approximations as well as to determine the degree of ...
Ab initio calculations were used to determine the equilibrium geometries and energies of lithium dimethylaminoborohydride. Relative energies of the monomeric and dimeric species were calculated in the gas phase and for the dimethyl ether microsolvated molecules. The most stable structure was a dimer in which the lithium and boron atoms were bridged by two ...
Accurate quartet- and doublet-state potential-energy surfaces for the interaction of a hydrogen atom and an oxygen molecule in their ground states have been determined from an ab initio calculation using large-basis sets and the internally contracted mult...
Ab initio and nonlocal density functional theory (DFT) calculations were performed to determine reaction mechanisms for formation of the six- membered ring C3N3Cl3 (cyanuric chloride) from the monomer, cyanogen chloride (ClCN). MP2 geometry optimizations ...
In this work, the structure of symmetric N2O3 was investigated using ab initio methods. Bond lengths and bond angles were determined using the 6-31 G* and the 6-311 G* basis sets using both SCF and MP2 theory. At the highest level of theory considered in ...
The barriers to internal rotation about the N-C bond of formamide and the formanide-H2O complex have been examined by ab initio quantum chemistry methods. Both selfconsistent field and correlated approaches have been utilized to determine the geometries, ...
The detailed molecular structures including the equilibrium conformations and energies of the four prototype phosphorus compounds exhibiting a phosphorus oxygen phosphorous(P-O-P) interconnection, H4P2O2n-1 for n=1 to 4, were determined by ab initio quant...
Ab initio molecular dynamics is used to compute the thermal conductivity of hydrogen at 80 g cm{sup -3} and temperature up to 800 eV. Pressures and ionic structure are compared with orbital-free calculations. Thermal conductivity is evaluated using the Kubo-Greenwood formula and is compared with models currently used in hydrodynamical simulations of inertial confinement ...
This paper reports the simultaneous determination of toxicokinetic and toxicodynamic properties of Androctonus australis hector venom, in the absence and presence of antivenom (F(ab'){sub 2} and Fab), in envenomed rats. After subcutaneous injection of the venom, toxins showed a complete absorption phase from the site of injection associated with a ...
Using a newly developed fluorescent nanoparticle (NP) that gives rise to a high-intensity and stable fluorescent light, a sensitive antibody (Ab) microarray assay system has been developed for specific detection of bioterrorism agents, as exemplified by ricin, cholera toxin (CT), and staphylococcal enterotoxin B (SEB). The Ab microarray uses a sandwich ...
The purpose of this study was to investigate degree of observer reliance (RD) on specific diagnostic elements in differential diagnosis of ameloblastoma (AB) and keratocystic odontogenic tumors (KOT) on panoramic images. The RD for 12 diagnostic elements, including 2 clinical and 10 radiographic elements, as recorded by eight dental radiologists on an ordinal ranking scale, ...
The literature concerning the subcellular location of Y-box binding protein 1 (YB-1), its abundance in normal and cancer tissues, and its prognostic significance is replete with inconsistencies. An explanation for this could be due in part to the use of different antibodies in immunohistochemical and immunofluorescent labeling of cells and tissues. The inconsistencies could also be due to poor ...
Previous research indicates that bilateral presentations of visual stimuli yield greater visual field differences than unilateral ones. Although this fact has generally been interpreted by reference to functional models of hemispheric specialization, an alternative explanation has been offered, which suggests that it is artifactually caused by an attentional bias (AB). Indeed, ...
Characterization of leukocytes is an integral part of blood analysis and blood-based diagnostics. In the present paper we combine lensless holographic imaging with antibody microarrays for rapid and multiparametric analysis of leukocytes from human blood. Monoclonal antibodies (Abs) specific for leukocyte surface antigens (CD4 and CD8) and cytokines (TNF-?, IFN-?, IL-2) were ...
Background. DFS70/LEDGF is a known survival factor, growth factor, and HIV-1 transporter. It is also an autoantigen recognized by IgG autoantibodies (aAbs) in patients with atopic dermatitis (AD). In the past few decades, various IgE aAbs against self-proteins have been identified in AD. Although DFS70 is considered to be one of these proteins, to date, ...
The diagnosis of asbestosis by the pathologist requires the presence of both parenchymal fibrosis and asbestos bodies (AB's). To determine how many AB's are necessary for the diagnosis, they counted them in histologic sections and tissue extracts from the lungs of 14 men with pulmonary fibrosis, a history of asbestos ...
Cultivation of genetically modified maize (Bt-maize; event MON810) producing recombinant ?-endotoxin Cry1Ab, leads to introduction of the insecticidal toxin into soil by way of root exudates and plant residues. This study investigated the fate of Cry1Ab in soil under long-term Bt-maize cultivation in an experimental field trial performed over nine growing ...
A novel density modification method is applied for the first time to phase reconstruction of x-ray single crystal data of quasicrystals. The structure of icosahedral Zn-Mg-Ho quasicrystals has been determined by means of this ab initio structure determination within a framework of a 6D description. The location, size, and shape of the ...
11 hybridoma cell lines secreting monoclonal antibodies (McAbs) against hemorrhagic fever with renal syndrome virus (HFRSV) were obtained in our laboratory by immunizing LOU/C rats with HFRSV Chen strain. These rat McAbs were characterized by radio-immunoprecipitation and western blotting methods, 2 directed against glycoprotein G2, 9 against nucleocapsid ...
Citation Ticconi C, Giuliani E, Veglia M, Pietropolli A, Piccione E, Di Simone N. Thyroid autoimmunity and recurrent miscarriage. Am J Reprod Immunol 2011 Problem? To investigate the role of antithyroid autoantibodies (ATA) in recurrent miscarriage (RM). Methods? In this case-control study, a total of 160 women with RM and 100 healthy women were investigated for the presence of serum ATA directed ...
Studies were performed to determine the effect of the radiolabel and circulating carcinoembryonic antigen (CEA) on the pharmacodynamics of monoclonal anti-CEA antibodies (MoAbs). The studies were performed in normal BALB/c mice and in nude mice bearing human colon tumors. Three different tumors were used, each of which produced CEA levels characteristic of ...
Radioactive cadmium telluride/zinc sulfide (Cd125mTe/ZnS) nanoparticles were targeted to mouse lung with antibody to mouse lung endothelium and quantified using radiological histology in order to test the in vivo targeting efficacy of a nanoparticle-antibody (NP-mAb) system. The nanoparticles were linked to either a monoclonal antibody to mouse lung thrombomodulin ...
The avidity of antibodies (Abs) to diphtheria Toxin (DT), toxoids (DTo) and the DT binding site (DTBS) was investigated in sera from guinea bigs vaccinated with various DTo. Measurement of avidity by the thiocyanate procedure revealed that, the maturation patterns of Abs to the corresponding DTo were not much different whereas the maturation patterns of ...
It is important to find biomarkers for autoimmune inflammation and demyelination in the CNS to monitor disease status in patients with multiple sclerosis (MS). For this purpose, we determined the titers of antibodies (Ab) reacting with native myelin oligodendrocyte glycoprotein (MOG)-expressing cells to evaluate the disease activity of chronic experimental ...
Antibodies (Abs) to CD20 and MHC class II antigen were found to exhibit a novel processing pathway after binding to the surface of RL B-lymphoma cells. The Abs were 'excreted' as a part of large cytoplasmic fragments. These fragments formed at cell-cell junctions, but gentle dispersal of the cells, to form a single-cell suspension of high viability, caused ...
Traumatic brain injury (TBI) induces the rapid formation of Alzheimer's disease (AD)-like amyloid-beta (AB) plaques in about 30% of patients. However, the mechanisms behind this selective plaque formation are unclear. We investigated a potential association between amyloid deposition acutely after TBI and a genetic polymorphism of the AB-degrading enzyme, ...
AbstractTraumatic brain injury (TBI) induces the rapid formation of Alzheimer's disease (AD)-like amyloid-? (AB) plaques in about 30% of patients. However, the mechanisms behind this selective plaque formation are unclear. We investigated a potential association between amyloid deposition acutely after TBI and a genetic polymorphism of the AB-degrading ...
Flourescent antibody test (FAT) was applied to determine the cross-reactivities of monoclonal (mAb), polyclonal (pAb) antibodies to Neospora, Toxoplasma and Cryptosporidium and antisera from cattle naturally infected with Neospora canium against antigens from a number of sources. Both mAb and ...
The binary molecular diffusion coefficients D AB of a vaporizing liquid in gases under atmospheric conditions were measured by the new simple barometric method. A change in the pressure of a vapor-gas mixture in a closed cell was determined as a function of time. Under experimental conditions, one can also find partial saturated vapor pressures of ...
The pH-dependent stability of a protein is strongly affected by electrostatic interactions between ionizable residues in the folded as well as unfolded state. Here we characterize the individual contributions of charged Glu and His residues to stability and determine the NMR structure of the designed, heterodimeric leucine zipper AB consisting of an acidic ...
Telomerase is a unique ribonucleoprotein complex that catalyzes the addition of telomeric DNA repeats onto the 3? ends of linear chromosomes. All vertebrate telomerase RNAs contain a catalytically essential core domain that includes the template and a pseudoknot with extended helical subdomains. Within these helical regions is an asymmetric 5-nt internal bulge loop (J2a/b) ...
Antisera were raised in rabbits against immunosorbent-purified F(ab')/sub 2/ fragments of IgG antitetanus toxoid (TT) antibodies obtained from three different donors. The antisera were rendered idiotype specific by absorption with insolubilized TT-nontreactive F(ab')/sub 2/. The resulting anti-idiotypic antisera precipitated more than 85% ...
For the equilibrium immiscible Fe-Cu system, ab initio calculations using the projector augmented wave method identify the relatively stable structures of the metastable Fe25Cu75 and Fe50Cu50 alloys to be both of fcc and determine their corresponding lattice constants and cohesive energies. Some of the ab initio calculated properties ...
... Sieves (Eds. ML Occelli and HE Robson), Van Nostrand Reinhard, New York, 1992 p 373. ... Dr. James S. Murday (1) Chemistry Division, Code 6100 ...
ABS>The saturated vapor pressure of boron (99.42% B with 0.18% hydrogen) at 1651 to 1764 deg K was determined by Knudsen effusion. The vapor pressure and heat of sublimation are tabulated. (R.V.J.)
Constants, represented as AV, AVA, AHA, AD, AB, and C, are used to determine the ... AHA: count2 (K volt)-1; others: count volt-1) [N/A] {Section 5.2.3.4 ...
Constants, represented as AV, AVA, AHA, AD, AB, and C, are used to determine the ... (AHA: count2 (K volt)-1; others: count volt-1) [N/A] {Section 5.2.3.4 ...
, D. F. and R. Price. 1939. Weather and plant development: d a t a as determinants of grazing. Grazing systems: objectives, definitons, controversies. Abs. Am. Soc. Range Manage. Annual Meeting
