include diabetic retinopathy, age-related macular degeneration, inherited retinal disease, pediatric
E-print Network
of an array of carbon nanotubes on a silicon chip for restoration of vision in patients with macular degeneration and other retinal disorders" ...
NASA Website
Age-Related Maculopathy; Age-Related Maculopathies; Eye Diseases; Retinal Degeneration; Macular Degeneration
ClinicalTrials.gov
to restore the vision of blind patients suffering from retinitis pigmentosa or macular degeneration categorized into macular degeneration and retinitis pigmentosa, these patients suffer from the degeneration pigmentosa or macular degeneration. Fig. 2. ...
Purpose:Agricultural and occupational exposures to the fungicides benomyl and captan and the insecticide fenthion have been associated with retinal degeneration. Exposure to insecticides has also been associated with pigmentary changes of the retina. Because retinal degeneration ...
EPA Science Inventory
Recent evidence suggests that Cl�� ion channels are important for retinal integrity. Because Cl�� channels regulate the ionic environment inside organelles in the endosomal-lysosomal pathway, retinal degeneration may result from defects in lysosomal trafficking or function.
NSDL National Science Digital Library
A new mouse retinal degeneration that appears to be an excellent candidate for modeling human retinitis pigmentosa is reported. In this degeneration, called rd-3, differentiation proceeds postnatally through 2 weeks, and photoreceptor degeneration starts by 3 weeks. The rod photoreceptor loss ...
Energy Citations Database
The findings of our study generally suggested that some types of farming and use of some pesticides were related to retinal degeneration. For example, farmers who raised orchard fruit (apples or peaches) were more likely to report this condition. Retinal degeneration was also more likely in farmers who raised ...
Cancer.gov
Age-Related Macular Degeneration; Wet Age-Related Macular Degeneration; Macular Degeneration; Eye Diseases; Retinal Diseases
... An electronic retinal prosthesis is under development to treat retinitis pigmentosa and age-related macular degeneration, two presently incurable ...
DTIC Science & Technology
... Abstract : An electronic retinal prosthesis is under development to treat retinitis pigmentosa and age-related macular degeneration, two presently ...
see Townes-Brocks Syndrome Rendu-Osler-Weber see hereditary hemorrhagic telangiectasia Reproductive Health Retinal Degeneration retinal detachment and occipital encephalocele...
Science.gov Websites
Glaucoma; Diabetic Retinopathy; Age-Related Macular Degeneration; Central Retinal Vein Occlusion; Branch Retinal Vein Occlusion
Age-Related Macular Changes; Age-Related Macular Degeneration; Cataract and IOL Surgery; Retinal Photochemistry
Retinal arterialization of a subretinal fibrous-tissue plaque has been observed clinically and by fluorescein angiography in three patients with senile disciform macular degeneration and one with presumed healed Toxocara chorioretinitis. This curious phen...
National Technical Information Service (NTIS)
The effects of experimental hypertension on retinal cells were studied. Evaluation was made of IOP levels and degree of cell damage by cytochemical and DNA analysis, and degeneration modes: necrosis and apoptosis. PMID:9972329
PubMed
diseases such as age-related macula degeneration (especially the dry form of the disease) and retinitis
... Specifically, degenerative disorders of the retina such as retinitis pigmentosa, macular degeneration, choroideremia, etc. ...
... optic nerve, and people suffering from retinitis pigmentosa, a progressive degeneration of the retina that results in tunnel vision and extreme sensitivity to light. ...
Retinal Stem Cells Transplanted into Models of Late Stages of Retinitis Pigmentosa Preferentially of Retinal Stem Cells Transplanted into RP Models 447 #12;successive immersions of the cell suspensions to the grafting procedure. Distribution of Retinal Stem Cells Subretinally Transplanted into Fully ...
Retinitis pigmentosa (RP) is a group of inherited neurodegenerative diseases in humans characterized by loss of photoreceptor cells leading to visual disturbance and eventually to blindness. A single systemic administration of N-methyl-N-nitrosourea (MNU) causes retinal degeneration in various animal species. The ...
Inherited retinal degenerations, including retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA), affect 1 in 4000 individuals in the general population. A majority of the genes which are mutated in these conditions are expressed in either photoreceptors or the retinal pigment epithelium (RPE). There is ...
PubMed Central
A new system for grading age-related maculopathy is described. A number of characteristics of age-related maculopathy (drusen size, type, area, and confluence; retinal pigment epithelial degeneration, increased retinal pigment, subretinal and sub-retinal ...
An electronic retinal prosthesis is under development to treat retinitis pigmentosa and age-related macular degeneration, two presently incurable diseases of the outer retina that afflict millions world-wide. Previous studies have established the feasibil...
Retinitis Pigmentosa; Macula Off; Primary Open Angle Glaucoma; Hereditary Macular Degeneration; Treated Retina Detachment; Retinal Artery Occlusion; Retinal Vein Occlusion; Non-Arthritic-Anterior-Ischemic Optic-Neuropathy; Hereditary Autosomal Dominant Optic Atrophy; Dry Age Related Macular ...
AMD; Wet AMD; Age-Related Macular Degeneration; Wet Age-Related Macular Degeneration; Macular Degeneration; Eye Diseases; Retinal Diseases
Retinitis pigmentosa (RP) is an inherited blinding disease characterized by progressive loss of retinal photoreceptors. There are numerous rodent models of retinal degeneration, but most are poor platforms for interventions that will translate into clinical practice. The rabbit possesses a number of desirable ...
We examined drug concentrations and the incidence of retinal degeneration in the eyes of albino BALB/c mice after a single intravenous administration of sitafloxacin plus a 4 h period of UVA irradiation. Retinal degeneration was induced at 40 mg/kg or more plus UVA irradiation, and there was little decrease in ...
Monogenic human retinal dystrophies are a group of disorders characterized by progressive loss of photoreceptor cells leading to visual handicap. Retinitis pigmentosa is a type of retinal dystrophy where degeneration of rod photoreceptors occurs at the early stages. At present, there are no available effective ...
Eight of nine individuals of a four-generation family had autosomal dominant central pigment epithelial and choroidal degeneration, which was not entirely consistent with previously described central retinal and choroidal degenerations. The early loss of the choriocapillaris with a relative sparing of the sensory ...
Using screening techniques of indirect ophthalmoscopy, electroretinography, and histology, we found inbred strains of Mus musculus molossinus to have a variable onset of retinal degeneration, which may present with early loss of outer segments and photoreceptor nuclei. The early affected mice have constricted vessels, optic atrophy, and markedly abnormal ...
: Exposure to the organophosphorous insecticide fenthion has been associated with retinal degeneration in occupational studies. It has also been associated with pigmentary changes of the retina. Because retinal degeneration and pigmentary changes may be due to dysfunction of t...
for the stimulation of remained retinal neurons in the patient with degenerated photoreceptors. Microelectrode arrays such as age-related macular degeneration (AMD) and reti- nitis pigmentosa (RP) is a leading cause of blindness layer cells in the macula survive at fairly high rate in the patients with RP [2] and AMD [3]. ...
Macular Degeneration; Age-Related Maculopathies; Age-Related Maculopathy; Maculopathies, Age-Related; Maculopathy, Age-Related; Retinal Degeneration; Retinal Neovascularization; Gene Therapy; Therapy, Gene; Eye Diseases
Eleven patients with geographic atrophy of the retinal pigment epithelium secondary to senil macular degeneration are differentiated from central areolar choroidal sclerosis. Although these lesions appear morphologically similar to central areolar choroidal sclerosis, they differ strikingly in age of onset, family history, association with senile disciform ...
With the development of stem cell technology, stem cell-based therapy for retinal degeneration has been proposed to restore the visual function. Many animal studies and some clinical trials have shown encouraging results of stem cell-based therapy in retinal degenerative diseases. While stem cell-based therapy is a promising strategy ...
Autosomal recessive Stargardt disease (STGD1) is a macular dystrophy caused by mutations in the ABCA4 (ABCR) gene. The disease phenotype that is most recognized in STGD1 patients, and also in the Abca4-/- mouse (a disease model), is lipofuscin accumulation in retinal pigment epithelium. Here, we tested whether delivery of the normal (wt) human ABCA4 gene to the subretinal ...
