... effects and random technician effects to partition the ... consent in this minimal risk trial. ... of coagulation factors, abdominal compartment syndrome, and ...

This is a demonstration you can use to show learners how valves and pumps work in concert to move blood through the circulatory system.

The blood of the lumbriculus is not pumped by a heart. The blood is pumped by contractions of the body of the worm. The circulatory system of the lumbriculus is much more simple than that of humans.

The catheter at the end of the insulin pump is inserted through a needle into the abdominal fat of a person with diabetes. Dosage instructions are entered into the pump's small ...

Blood in the splanchnic vasculature can be transferred to the extremities. We quantified such blood shifts in normal subjects by measuring trunk volume by optoelectronic plethysmography, simultaneously with changes in body volume by whole body plethysmography during contractions of the diaphragm and abdominal muscles. Trunk volume changes with blood shifts, but body volume ...

The areas of technical effort were; the evaluation of circulatory assist devices in animals, the development of myocardial failure (ischemic) animal models, the evaluation of total heart replacement biventricular blood pumps, the evaluation of 'cup squeez...

This video segment describes the basics of the circulatory system: how the heart pumps the blood that carries oxygen and nutrients throughout the body.

Cardiopulmonary bypass developed for studies of long term weightlessness on cardiovascular system of

This video segment describes the basics of the circulatory system: how the heart pumps the blood that carries oxygen and nutrients throughout the body.

... The HeartMate II LVAS consists of an implanted continuous axial flow blood pump and external components. The blood pump has one ...

Heat is recovered by combining a heat transfer system including heat exchangers interconnected in a circulatory system, with a heat pump system. The heat pump system is preferably operated in accordance with the Lorenz-Principle. It is not necessary to divide the heat carrier circuit of the heat pump into two or ...

One of possible cardiac failure therapy is mechanical heart supporting. The following types of ventricular assist devices (VAD) are clinically used: diaphragm displacement, centrifugal and axial pumps. Each of supporting devices produces different hemodynamical effect and affects the circulatory system in various ways. It causes impossibility of ...

... Aortic Aneurysm Reference Summary Introduction Ballooning of the aorta, also known as an "abdominal aortic aneurysm," can ... the benefits and risks of this surgery. Anatomy Aorta Common Illiac Arteries The heart pumps blood into ...

The circulatory system includes the heart, blood vessels, and blood. Arteries take blood with oxygen to our organs; veins bring deoxygenated blood to the heart (to be pumped to the lungs to get oxygen). Arteries and veins bring essential nutrients from digestion (such as glucose) to our tissues as well.

The heart is located within our chests and is central to the function of the circulatory system. The heart pumps blood to the lungs to be oxygenated. The heart also pumps blood to the organs of the body. The rate that the heart beats depends on the needs of the body.

The conceptual design and development of a long-term, low-profile intracorporeal left ventricular assist device is a multifaceted project involving a series of technical, anatomic and physiologic considerations. Patients with severe left ventricular failure refractory to all other forms of therapy could benefit from such a device. Prior to fabrication of such a blood pump, ...

... grasshoppers the ventilatory motor pattern that drives abdominal pumping is intermittent (Harrison, 1997). Often the first behavioural ... 1975) and alert animals exhibit a continuous abdominal pumping. I...

The circulatory system would also have problems because it would be harder for the heart to pump blood up to the head. The animal might feel faint. ...

... or biventricular support), cannulae for the connection of the blood pumps to the ... that the Agency is not responsible for providing access to electrical outlets. ...

The use of circulatory support as destination therapy has been a goal for the treatment of endstage heart failure for several decades. Current investigations are evaluating several circulatory pumps with that particular objective. With continued modification of design, the current and future pumps will become more ...

Mechanical heart supporting is one of possible therapy in case of circulatory system insufficiency. Each of ventricular assist devices affect the circulatory system by various way. A lack of predefined physical ratios describing heart assist device influence on circulatory system is a problem during establishing brief foredesign of new ...

The engineering principles of rotary blood pumps are elucidated by means of a basic introduction into turbomachinery. Additionally, some important dimensionless quantities which relate to pumping characteristics and pump type are introduced. These theoretical fundamentals are applied to the design of high-speed microaxial ...

The body must dissipate the reject heat from the power source which drives the blood pump(s) of an implantable circulatory support system. Radioisotope heat sources also expose the body to nuclear radiation. The objective of these studies is to characteri...

The Daphnia contains a heart, but no blood vessels. The Daphnia has an open circulatory system, meaning blood moves freely in the body. Use these examples to understand that organ systems can be simple or very complex, but their functions are the same. Blood is moved through the body of the Daphnia by the pumping heart.

Continuous flow blood pumps, such as axial flow and centrifugal pumps, have been gaining interest as circulatory devices for total artificial hearts (TAHs) because of their smaller size and simpler structure compared to pulsatile pumps. However, continuous flow pumps are more prone to atrial ...

Abdominal aortic aneurysms occasionally occur concomitantly with an intracranial artery aneurysm (ICA). The association of an ICA with a thoracoabdominal aortic aneurysm (TAAA) is relatively rare. A patient with this condition is presented. Coiling of the ICA was not an option preoperatively because of the dissected false lumen of the TAAA, rendering a femoral artery approach ...

The use of a flexible polyvinyl tube bonded with tridodecylmethylammonium-heparin (Gott) as a temporary shunt during the resection of lesions of the descending thoracic aorta has proven a safe and simple means of providing adequate circulation to the abdominal viscera and spinal cord. This technique avoids the metabolic consequences of ischemia to the lower body, diminishes ...

The abdominal left ventricular assist device (ALVAD) is an order of magnitude more effective than conventional intra-aortic balloon pumping (IABP) in unloading and providing circulatory support to the failing left ventricle. This is a report of a unique case which demonstrates that in the absence of pulmonary vascular obstruction or ...

Continuous flow blood pumps, such as axial flow and centrifugal pumps, have been gaining interest as circulatory devices for total artificial hearts (TAHs) and a biventricular assist device (BVAD) because of their smaller size and simpler structure compared to pulsatile pumps. However, continuous flow ...

In various conditions of blood demand of circulatory system, the autonomic regulations system of body regulates the heart rate (HR) to maintain the arterial pressure (AP) constant, where the HR is considered as the controlled variable indicating the blood demands of the circulatory system. Therefore, model-free adaptive controller is used to regulate the ...

The third annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) provides documentation of the current landscape of durable mechanical circulatory support in the United States. With nearly 3,000 patients entered into the database, the transition to continuous-flow pump technology is evident ...

Since the 1960s, the Texas Heart Institute has been intimately involved in the development of mechanical circulatory support devices (for example, ventricular assist devices, aortic counterpulsation pumps, and total artificial hearts) for both short- and long-term use. Here, we review the varied clinical experience with these technologies at the Texas ...

An evaluation of the auxiliary ventricle arterio-arterial blood pump, with regard to objectives, man-power, equipment and facilities was made. The calf was selected as a more suitable animal model than the sheep or mini-pig for the evaluation of the auxil...

The mechanical durability of an elastomer is a critical factor in its suitability for blood pump applications. In such applications, an elastomeric bladder is expected to undergo cyclic stress or strain histories at a frequency of approximately 1 Hz for p...

The circulatory system of humans is closed, meaning that blood is enclosed by blood vessels. This image is that of an open system, meaning the blood moves freely throughout the body. In both systems, blood is pumped to the tissues of the body and then nutrients diffuse into the cells of those tissues.

A left ventricular assist device for long-term circulatory support to be powered by implantable electrical actuation systems is being developed. The parathoracic ventricular assist device (PVAD) for human use resembles the prototype bovine version; howeve...

A left ventricular assist device intended for long term circulatory support to be powered by implantable electrical actuation systems is being developed. The Model 12C parathoracic ventricular assist device (PVAD) is designed specifically for ultimate hum...

The report describes in detail the pump and control system development, in vitro test results, surgical implantation, physiologic studies and hemodynamic evaluation. The results of a total of 47 calf experiments with survivals for five or more days are di...

... a premarket approval application, P920014/S016, for the HeartMate Vented Electric Left Ventricular ... use of the device as a permanent heart pump for destination ...

A reactor vessel for reacting a solid particulate with a liquid reactant has a centrifugal pump in circulatory flow communication with the reactor vessel for providing particulate attrition, resulting in additional fresh surface where the reaction can occur.

A reactor vessel for reacting a solid particulate with a liquid reactant has a centrifugal pump in circulatory flow communication with the reactor vessel for providing particulate attrition, resulting in additional fresh surface where the reaction can occur. 2 figures.

Contents include: Special methods in the assessment of patients with acute myocardial infarction; Pharmacolgic measures in the treatment of acute myocardial infarction; Circulatory support in acute myocardial infarction by intra-aortic balloon pumping; Re...

We have been developing an electrohydraulic total artificial heart (EHTAH) system. The system consists of diaphragm blood pumps, an abdominally placed energy converter, an internal controller, a transcutaneous energy transfer (TET) system, a transcutaneous optical information transfer system, and internal and external lithium-ion (Li-ion) batteries. The ...

Highly complex vascular surgery interventions have nowadays become possible due to sophisticated operative techniques and modern intra- and postoperative anesthesiological strategies. Accordingly, the number of high risk vascular surgery interventions rises continuously and thus, the number of secondary complications after high risk interventions increases as well and requires likewise ...

This article describes comparative studies of a newly developed "straight path" centrifugal pump (Capiox centrifugal pump) targeted for open-heart surgery and circulatory support. A unique straight path design of the rotor was very effective in reducing the pump's rotational speed and prime volume. This ...

A device that generates negative extra-abdominal pressure (ABDOPRE) for treatment of patients with high intra-abdominal pressure was developed. It includes pressure sensors for transducing intra-abdominal pressure through an intra-vesical catheter and negative pressure in the vacuum bell which is placed over the abdomen. By means of a ...

Patients with arterio-venous fistula of the splenic hilum seek medical assistance because of abdominal discomfort and symptoms of portal hypertension. We report on a 43 year old female who was diagnosed with an arterio-venous aneurysm after suffering from dyspnoea, tachycardia and extrasystolies for several years. After uncomplicated distal splenopancreatectomy the patient was ...

A multidiscipline group was established at The Pennsylvania State University to design and evaluate mechanical circulatory assist devices and the artificial heart. The group has designed a left ventricular to aortic assist system which consists of a sac-type pump, a synchronization unit, a pneumatic power unit, and appropriate monitoring apparatus. The ...

A strategy employing moderate hypothermia for replacement of the aortic arch is proposed to avoid the complications of profound hypothermic circulatory arrest. Two patients underwent complete replacement of the aortic arch using three pumps (Figure 1a - one to perfuse the brain, one for the thoracoabdominal aorta and the third for the heart). There were no ...

The embryonic vertebrate heart is a compliant dynamic tube that develops into a multi-chambered multi-valve geometry at later stages. Even at these early stages, the tubular embryonic heart pumps blood to sustain the circulatory system. The prevailing understanding of the pumping mechanism at these stages describes the heart tube as a ...

An energy system with the considered vapor cycle heat engine is to power an assist heart pump in synchronous operation with the biologic heart and to achieve a significant reduction of left ventricle pressure. The engine, known as the tidal regenerator engine (TRE), has been incorporated into a nuclear-powered implantable system. The system has been extensively tested on an ...

There is significant interest in the development and application of variable speed impeller-pump type ventricular assist devices designed to generate pulsatile blood flow. However, no study has so far been carried out to investigate the systemic cardiovascular response to various aspects of pump motion. In this article, a numerical model is constructed for ...

Circulatory, respiratory, and digestive motions in Manduca sexta pupae were observed using proton-density weighted and fast-imaging with steady-state free procession magnetic resonance microscopy. Proton-density weighted images clearly differentiated pupal air sacs from the hemolymph and organs because, as expected, the air sacs appeared dark in these images. Steady-state free ...

A female patient with a chronic pain syndrome after multiple operation on her muskuloskeletal system presented with a displaced pain pump in her lower left abdominal region. After an excessive weight loss due to gastric banding the patient developed a massive pendulous abdomen causing the complication. An interdisciplinary dermatolipectomy together with a ...

The TinyPump is an extracorporeal, magnetically driven centrifugal blood pump with its impeller suspended magnetically and hydrodynamically to provide short-term mechanical circulatory support for children and infants. We have previously demonstrated that the in vivo experiments of the experimental TinyPump showed ...

Repairing a parietal defect of a large incisional hernia should not be limited to the closure of the breach by means of the modern biocompatible prosthetic sheets, but must also be able to restore a correct intra abdominal pressure, otherwise the derangement from the normal respiratory dynamics and the circulatory stasis in the ...

The Levitronix UltraMag blood pump is a next generation, magnetically suspended centrifugal pump and is designed to provide circulatory support for pediatric and adult patients. The aim of this study is to investigate the hemodynamic and hemolytic characteristics of this pump using the computational fluid dynamics ...

This article reports a case of acute pancreatitis in a patient taking the oral contraceptive pill. A 32 year old mother had been on combined contraceptive pills since 1975. In 1978 she started having upper abdominal and retrosternal pain. She became critically ill with peripheral circulatory collapse, dyspnoea and cyanosis. A superficial ...

A 74-year-old woman was admitted to our hospital with upper abdominal pain and bloody vomiting. An abdominal aneurysm compressed the third portion of the duodenum and the second portion of duodenum was distended with thickened walls as in superior mesenteric artery syndrome. Endoscopic examination showed an edematous mucosa with hemorrhagic erosions, ...

In a nuclear reactor installation secured against rupture and has a pressurized water reactor, and a straight-tube steam generator having a central ascending pipe, a coolant pump and lines connecting them in a primary circulatory loop. The coolant pump is installed in a primary chamber of the steam generator and forms with the latter a ...

A computer-assisted measuring system for the noninvasive control of pneumatically driven blood pumps in the artificial total heart replacement and in assist-systems is described. Air volume current measurements with heat wire anemometer in the driving tube underlie as principle. The technique takes into consideration losses of valves, depending upon driving parameters and ...

The hemocompatibility of a newly developed monopivot circulatory assist pump was evaluated by the computational fluid dynamic (CFD) analyses with the particle tracking velocimetry measurement. Results were compared with those of the hemolysis test and in vitro antithrombogenic test to prevent hemolysis and thrombus formation inside the ...

We present four cases of heavy metal poisoning (mercury, lead, bismuth and arsenic) in which plain chest and/or abdominal assisted in the differential diagnosis of the clinical picture manifested upon admission at our Emergency Department. The patients suffering from mercury, lead, and bismuth poisoning recovered some weeks after treatment was started. However, the patient ...

ventricular assist device (LVAD) is a mechanical pump to restore the blood flow for end-stage congestive heart- ical Control for a Continuous Flow Ventricular Assist Device, Artificial Organs 23(6): 480-487, 1999 Flow Ventricular Assist Device, ASAIO J 48: 272-289, 2002. [13] Boston JR, Simaan MA, Antaki JF, Yu Y

: Plasma Plasma is a watery fluid that forms matrix of blood Normally about 55% of blood by volume Has a p to the right Components of the Cardiovascular System Blood Connective tissue which transports material Blood vessels Tubes of various size which contain the blood Heart Muscular pumping organ #12;2 Blood Component I

When we exercise, the heart works extra hard to pump blood to the lungs to pick up oxygen and then throughout the body to bring oxgyen and glucose to the cells for cellular respiration (a process to make the energy we need to exercise). Glucose is brought to the body, first by digestion and absorption of the food we eat, and then by circulation of the glucose via the ...

Circulating blood cells function as a surveillance system for damaged tissue in Drosophila larvae October 18, 2007) Insects have an open circulatory system in which the heart pumps blood (hemolymph) into the body cavity, where it directly bathes the internal organs and epidermis. The blood contains free

The most common complication after abdominoplasty is seroma formation. The incidence of seroma formation in abdominal procedures as a whole, including abdominoplasty, panniculectomy and transverse rectus abdominis myocutaneous flap abdominal donor sites, ranges from 1% to 38%. A recent concern among surgeons is the possibility of a causal relationship ...

Myocardial dysfunction leading to low cardiac output syndrome is a common clinical pathophysiological state. Currently, the use of mechanical circulatory support (MCS) is an essential aspect of the treatment of patients with cardiac failure. Several groups in China are engaged in the design and development of MCS devices. These devices can be classified as pulsatile, rotary, ...

... Title : Feedback Control of Circulatory Elastic Systems,. ... Abstract : Stability of a system with two degrees ... subjected to a follower (circulatory) force is ...

Merging numerical and physical models of the circulation makes it possible to develop a new class of circulatory models defined as hybrid. This solution reduces the costs, enhances the flexibility and opens the way to many applications ranging from research to education and heart assist devices testing. In the prototype described in this paper, a hydraulic model of systemic ...

OBJECTIVE: By using deep hypothermic circulatory arrest and non-deep hypothermic circulatory arrest approaches, we examined the impact of distal ischemia time and temperature on intra-abdominal reversible adverse outcomes and permanent adverse outcomes during descending thoracic aortic and thoracoabdominal aortic aneurysm operations. ...

An overview from an evolutionary perspective is presented on the research of the past 2 decades on insect circulatory organs. Based on various functional morphology it is clear that the flow mode of the dorsal vessel ('heart') has changed during the evolution of hexapods. In all apterygotes and mayflies the flow is bidirectional. In most pterygote insects, however, it is ...

Even though clinical acceptance of a nonpulsatile blood flow was demonstrated almost 45 years ago, the development of a nonpulsatile blood pump was completely ignored until 20 years ago. In 1979, the first author's group demonstrated that completely pulseless animals did not exhibit any abnormal physiology if 20% higher blood flows were provided to them. However, during the ...

A centrifugal pump with a unique structure has been developed for chronic support. The pump is driven by a magnetic coupling and has no rotating shaft, no seal around the rotating part, and a balancing hole at the center of the impeller and the thrust bearing. The pump was improved in stepwise fashion to realize good ...

The Gyro Pump C1E3 is a new centrifugal pump with numerous features, including a ceramic pivot bearing system, secondary vanes, and an eccentric inlet port. To evaluate its biocompatibility, antithrombogenicity, and produced hemolysis, we used the Gyro Pump during cardiopulmonary bypass (CPB) for coronary artery bypass grafting (CABG) ...

The number of pediatric patients requiring some form of mechanical circulatory assistance is growing throughout the world because of new surgical procedures and the success of pediatric cardiac transplantation. However, the salvage rate for those patients requiring circulatory support may be as low as 25%. Despite the fact that Penn State's 70 cc pneumatic ...

In this study, a seal-less, tiny centrifugal rotary blood pump was designed for low-flow circulatory support in children and infants. The design was targeted to yield a compact and priming volume of 5 ml with a flow rate of 0.5-4 l/min against a head pressure of 40-100 mm Hg. To meet the design requirements, the first prototype had an impeller diameter of ...

Previous studies show that stimulated skeletal muscle wrapped around the heart or a blood pumping pouch can provide partial circulatory assistance. However, skeletal muscle is accustomed to pulling in direct tension, and power obtained from using the muscle in wraparound configurations is very inefficient. Therefore we have developed a new skeletal ...

The constantly increasing complexity and duration of surgical intervention, comorbidity that leads to severe circulatory and respiratory disorders, multifactoriness of functional and metabolic disorders--this also needs a rapid and accurate assessment of patients and objective monitoring. The value of monitoring is determined by the results of timely diagnosis of disorders and ...

The growing number of patients suffering from severe congestive heart failure (HF) worldwide still means a challenge for the therapeutic options, mainly in the older population. According to the rapid development in the possibilities for mechanical circulatory support (MCS), the increasing use of left ventricular assist devices (LVADs) as bridge to transplantation (BTT) or ...