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1
Listening: the key to diagnosing spasmodic dysphonia.
2008-01-01

Spasmodic dysphonia (SD) is a focal dystonia of the larynx. Adductor spasmodic dysphonia (ADSD) involves the laryngeal adductor muscles, and symptoms of vocal roughness, staccato-like sounds, and stops in phonation. Abductor spasmodic dysphonia (ABSD) ...

PubMed

2
[Treatment of spasmodic dysphonia with botulinum toxin].
1991-01-01

Spasmodic dysphonia is a focal laryngeal dystonia, a rare form of dystonia. Videostroboscopy, acoustic analysis, computerized voice analysis and over all electrophysiological analysis allow for the study of the different muscles involved in this dysphonia. There are two types of spasmodic ...

PubMed

3
[Diagnostic and therapeutic difficulties in laryngeal dystonia].
2003-01-01

Spasmodic dysphonia is a focal laryngeal dystonia. It presents as: adductor spasmodic dysphonia with the strain-strangle voice; abductor spasmodic dysphonia with whispering voice and breathy breaks in connected speech; and adductor respiratory dystonia ...

PubMed

4
Botulinum toxin for the treatment of spasmodic dysphonia.
2000-08-01

Spasmodic dysphonia is a focal laryngeal dystonia. Laryngeal dystonia presents as: adductor spasmodic dysphonia with the characteristic strain-strangle voice; abductor spasmodic dysphonia with hypophonia and breathy breaks in connected speech; and ...

PubMed

5
Spasmodic dysphonia and botulinum toxin: experience from the largest treatment series.
2010-07-01

Spasmodic dysphonia is a focal laryngeal dystonia, with adductor, abductor, mixed, respiratory and singer's types. Our series over 24 years includes 1300 patients. 82% are of the adductor type; 63% were female; 12% had a positive family history and 82.4% had a focal distribution. All of the patients were managed with varying degrees of ...

PubMed

6
[Therapeutic difficulties in spasmodic dysphonia--case report].
2006-05-01

Spasmodic dysphonia is a focal form of laryngeal dystonia that causes unintended contractions of vocal folds with speech interruptions and affecting the voice quality. There are adductor (82%), abductor (36%), mixed (1%) types and reported by Blitzer--respiratory adductor type with paradoxical vocal fold movement and stidor. As an ...

PubMed

7
[Indications for botulinum toxin in laryngectomy].
1993-01-01

The botulinum toxin is a highly potent neurotoxin, used since several years in the treatment of the focal musculary dystonias. We define the laryngeal dystonia as a clinical entity, which is represented by a spasmodic dysphonia or an inspiratory dyspnea without dysphonia, related to a specific dystonia of the thyroarytenoid muscles. ...

PubMed

8
Spasmodic Dysphonia

... bacterium that occurs in improperly canned foods and honey. The toxin weakens muscles by blocking the nerve ...

MedlinePLUS

9
Spasmodic Dysphonia

... in an area of the brain called the basal ganglia. The basal ganglia consist of several clusters of nerve cells deep ...

MedlinePLUS

10
Spasmodic dysphonia: a laryngeal control disorder specific to speech.
2011-01-19

Spasmodic dysphonia (SD) is a rare neurological disorder that emerges in middle age, is usually sporadic, and affects intrinsic laryngeal muscle control only during speech. Spasmodic bursts in particular laryngeal muscles disrupt voluntary control during vowel sounds in adductor SD and interfere with voice onset after voiceless ...

PubMed

11
Spasmodic dysphonia: clinical features and effects of botulinum toxin therapy in 169 patients-an Australian experience.
2003-07-01

Adductor spasmodic dysphonia (SD) is a focal laryngeal dystonia, characterised by strangled, effortful speech with breaks in pitch and phonation. Injection of laryngeal muscles with BTX is widely used in the treatment of SD. A consecutive series of 169 patients with SD, of whom 144 were treated with BTX injections, seen at St. Vincent's Hospital between ...

PubMed

12
Abnormal activation of the primary somatosensory cortex in spasmodic dysphonia: an fMRI study.
2010-03-01

Spasmodic dysphonia (SD) is a task-specific focal dystonia of unknown pathophysiology, characterized by involuntary spasms in the laryngeal muscles during speaking. Our aim was to identify symptom-specific functional brain activation abnormalities in adductor spasmodic dysphonia (ADSD) and ...

PubMed

13
Spasmodic dysphonia

The voice is usually hoarse or grating. It may waver and pause. The voice may sound strained or strangled, and it may seem as if the speaker has to ...

MedlinePLUS

14
Botulinum toxin therapy of laryngeal muscle hyperactivity syndromes: comparing different botulinum toxin preparations.
2006-02-01

Spasmodic dysphonia (SD) is a focal dystonia characterized by a strained, strangled voice. Botulinum toxin is a symptomatic treatment for SD and has become the mainstay of therapy over the last two decades. In this manuscript, we briefly review different laryngeal muscle hyperactivity syndromes, their injection techniques and toxins currently available. ...

PubMed

15
Research Priorities in Spasmodic Dysphonia
2008-10-01

OBJECTIVETo identify research priorities for increasing understanding of the pathogenesis, diagnosis and improved treatment of spasmodic dysphonia.STUDY DESIGN AND SETTINGA multidisciplinary working group was formed including both scientists and clinicians from multiple disciplines, otolaryngology, neurology, speech pathology, genetics and neuroscience, to ...

PubMed Central

16
The use of botulinum toxin in the treatment of adductor spasmodic dysphonia.
1993-05-01

Botulinum toxin injections have been used to treat 31 patients with adductor spasmodic dysphonia. Injections of 3.00-3.75 units of botulinum toxin were performed bilaterally into the thyroarytenoid muscle. This treatment significantly decreased the standard deviation of the fundamental frequency of the speech sample, indicating a reduction in the ...

PubMed Central

17
Brainstem pathology in spasmodic dysphonia.
2010-01-01

Spasmodic dysphonia (SD) is a primary focal dystonia of unknown pathophysiology, characterized by involuntary spasms in the laryngeal muscles during speech production. We examined two rare cases of postmortem brainstem tissue from SD patients compared to four controls. In the SD patients, small clusters of inflammation were found in the reticular formation ...

PubMed

18
Brainstem pathology in spasmodic dysphonia
2010-01-01

Spasmodic dysphonia (SD) is a primary focal dystonia of unknown pathophysiology, characterized by involuntary spasms in the laryngeal muscles during speech production. We examined two rare cases of postmortem brainstem tissue from SD patients compared to four controls. In SD patients, small clusters of inflammation were found in the reticular formation ...

PubMed Central

19
Clinical aspects of spasmodic dysphonia.
1978-04-01

The clinical features of 12 patients with spasmodic dysphonia are described. In 11 patients, the voice was strained, harsh, tight, and tremulous, and was low in volume and pitch. Speech, which was sometimes barely intelligible, was interrupted by irregular stoppages and catches of the voice; it required considerable effort, and was accompanied by facial ...

PubMed Central

20
The innervation of the posterior cricoarytenoid muscle: exploring clinical possibilities.
2007-05-16

Manipulation of the nerve supply to the posterior cricoarytenoid (PCA) muscle has potential for ameliorating the symptoms of some neurologic conditions such as abductor spasmodic dysphonia. The anatomy of the nerve supply to the PCA is better understood than in previous eras, but the anatomical understanding has not translated to ...

PubMed

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21
Vocal aging and adductor spasmodic dysphonia: Response to botulinum toxin injection
2008-03-01

Aging of the larynx is characterized by involutional changes which alter its biomechanical and neural properties and create a biological environment that is different from younger counterparts. Illustrative anatomical examples are presented. This natural, non-disease process appears to set conditions which may influence the effectiveness of botulinum toxin injection and our expectations for its ...

PubMed Central

22
Treatment for spasmodic dysphonia: limitations of current approaches
2009-06-01

Purpose of reviewAlthough botulinum toxin injection is the gold standard for treatment of spasmodic dysphonia, surgical approaches aimed at providing long-term symptom control have been advancing over recent years.Recent findingsWhen surgical approaches provide greater long-term benefits to symptom control, they also increase the initial period of side ...

PubMed Central

23
[Is stuttering a functional dystonia?].
2002-01-01

For some years the dystonias have been the subject of major studies and, as far as the generalised dystonias are concerned, of major therapeutic advances. The opposite is true of the so-called focal or functional dystonias, which include conditions such as Meige's syndrome, spasmodic torticollis, writer's cramp, dystonias using instruments especially in musicians, and ...

PubMed

24
Perioral reflexes in orofacial dyskinesia and spasmodic dysphonia.
1992-09-01

In order to assess the clinical utility of trigemino-facial reflexes in lower facial muscles, we studied perioral reflexes to mechanical and electrical stimulation in 13 patients with spasmodic dysphonia and orofacial dyskinesia and in 7 healthy subjects. Mechanical stimulation of the upper lip of all patients and electrical stimulation of the infraorbital ...

PubMed

25
[Movement disorders in David Copperfield].

Charles Dickens' novels are a source of vivid neurological descriptions. Besides Pickwickian syndrome, many other neurological descriptions can be found in Dickens' novels. David Copperfield contains several characters with movement disorders including generalized dystonia (Mr. Uriah Heep), restless legs syndrome (the waiter), cervical dystonia (Mr. Sharp) and spasmodic ...

PubMed

26
The Consequences of Spasmodic Dysphonia on Communication-Related Quality of Life: A Qualitative Study of the Insider's Experiences
2005-09-01

The purpose of this study was to explore the biopsychosocial consequences of spasmodic dysphonia (SD) as experienced by people with SD. Qualitative research methods were used to investigate the insider's perspective of living with SD. Six adults with SD participated in face-to-face phenomenological interviews. The results are summarized in a model of ...

ERIC Educational Resources Information Center

27
Patient perceptions of factors leading to spasmodic dysphonia: A combined clinical experience of 350 patients.
2011-07-20

PURPOSE: Spasmodic dysphonia (SD) is an idiopathic voice disorder that is characterized by either a strained, strangled voice quality or a breathy voice with aphonic segments of connected speech. It has been suggested that environmental factors play a role in triggering the onset. Clinical observation suggests that some patients associate onset with ...

PubMed

28
Thalamo-olivary degeneration in a patient with laryngopharyngeal dystonia.
1995-10-01

A 67 year old woman with a two year history of laryngopharyngeal dystonia, spasmodic dysphonia, and parkinsonism succumbed to Wernicke's encephalopathy and died six months later. Necropsy showed, besides Wernicke's encephalopathy, degenerative changes in selected thalamic nuclei (dorsomedial, pulvinar, and the medial geniculate bodies) and the inferior ...

PubMed Central

29
Unilateral versus bilateral thyroarytenoid Botulinum toxin injections in adductor spasmodic dysphonia: a prospective study
2009-10-24

ObjectivesIn this preliminary prospective study, we compared unilateral and bilateral thyroarytenoid muscle injections of Botulinum toxin (Dysport) in 31 patients with adductor spasmodic dysphonia, who had undergone more than 5 consecutive Dysport injections (either unilateral or bilateral) and had completed 5 concomitant self-rated efficacy and ...

PubMed Central

30
Adductor spasmodic dysphonia: Relationships between acoustic indices and perceptual judgments
2003-04-01

This study investigated relationships between acoustical indices of spasmodic dysphonia and perceptual scaling judgments of voice attributes made by expert listeners. Audio-recordings of The Rainbow Passage were obtained from thirty one speakers with spasmodic dysphonia before and after a BOTOX injection of the ...

NASA Astrophysics Data System (ADS)

31
[Abnormal adductor movement of the vocal cords in spasmodic dysphonia].
1993-04-01

Adductor movement of the vocal cords in initial/ke/phonation was recorded using a laryngeal fiberscope, CCD camera, and videocassette recorder. Three patients with adductor spasmodic dysphonia (SD), a 53 year old male and 48 and 52 year old females, and 7 normal volunteers participated in this study. During the examination, the subject sat on a chair ...

PubMed

32
The consequences of spasmodic dysphonia on communication-related quality of life: A qualitative study of the insider's experiences

The purpose of this study was to explore the biopsychosocial consequences of spasmodic dysphonia (SD) as experienced by people with SD. Qualitative research methods were used to investigate the insider's perspective of living with SD. Six adults with SD participated in face-to-face phenomenological interviews. The results are summarized in a model of ...

PubMed Central

33
The Psychosocial Consequences of BOTOX Injections for Spasmodic Dysphonia: A Qualitative Study of Patients� Experiences
2006-03-29

SummaryObjectives/HypothesisThe purpose of this study is to examine the psychosocial consequences of BOTOX� (Allergan, Inc. Irvine, CA) treatment for spasmodic dysphonia (SD). This article also explores how patients judge the success of treatment and make decisions about future treatment based on psychosocial issues relevant to them.Study DesignThis ...

PubMed Central

34
Temporal discrimination thresholds in adult-onset primary torsion dystonia: an analysis by task type and by dystonia phenotype.
2011-06-01

Adult-onset primary torsion dystonia (AOPTD) is an autosomal dominant disorder with markedly reduced penetrance. Sensory abnormalities are present in AOPTD and also in unaffected relatives, possibly indicating non-manifesting gene carriage (acting as an endophenotype). The temporal discrimination threshold (TDT) is the shortest time interval at which two stimuli are detected to be asynchronous. We ...

PubMed

35
Speech Intelligibility in Severe Adductor Spasmodic Dysphonia
2004-02-01

This study compared speech intelligibility in nondisabled speakers and speakers with adductor spasmodic dysphonia (ADSD) before and after botulinum toxin (Botox) injection. Standard speech samples were obtained from 10 speakers diagnosed with severe ADSD prior to and 1 month following Botox injection, as well as from 10 age- and gender-matched healthy ...

ERIC Educational Resources Information Center

36
Focal white matter changes in spasmodic dysphonia: a combined DTI and neuropathological study
2007-12-14

Spasmodic dysphonia (SD) is a neurological disorder characterized by involuntary spasms in the laryngeal muscles during speech production. Although clinical symptoms of SD are well characterized, the pathophysiology of this voice disorder is unknown. We describe here, for the first time to our knowledge, disorder-specific brain abnormalities in SD patients ...

PubMed Central

37
Endoscopic Laser Thyroarytenoid Myoneurectomy in Patients with Adductor Spasmodic Dysphonia: A Pilot Study on Long-Term Outcome on Voice Quality.
2011-09-21

OBJECTIVES: Adductor spasmodic dysphonia (ADSD) is a focal laryngeal dystonia, which compromises greatly the quality of life of the patients involved. It is a severe vocal disorder characterized by spasms of laryngeal muscles during speech, producing phonatory breaks, forced, strained and strangled voice. Its symptoms result from involuntary and ...

PubMed

38
Developing the Communicative Participation Item Bank: Rasch Analysis Results from a Spasmodic Dysphonia Sample
2009-10-01

Purpose: The purpose of this study was to conduct the initial psychometric analyses of the Communicative Participation Item Bank--a new self-report instrument designed to measure the extent to which communication disorders interfere with communicative participation. This item bank is intended for community-dwelling adults across a range of communication disorders. Method: A set of 141 candidate ...

ERIC Educational Resources Information Center

39
Developing the Communicative Participation Item Bank: Rasch Analysis Results From a Spasmodic Dysphonia Sample
2009-08-28

PurposeThe purpose of this study was to conduct the initial psychometric analyses of the Communicative Participation Item Bank�a new self-report instrument designed to measure the extent to which communication disorders interfere with communicative participation. This item bank is intended for community-dwelling adults across a range of communication disorders.MethodA set of 141 candidate items ...

PubMed Central

40
Clinical approach to monitoring variability associated with adductor spasmodic dysphonia.
2011-08-01

ABSTRACTObjectives:Adductor spasmodic dysphonia (ADSD) is a voice disorder characterized by considerable intra- and intersubject variability. Although objective, acoustic measures of voice may provide a metric for ADSD, such measures can be inefficient in documenting such characteristics. This project integrated a simple auditory-perceptual measure termed ...

PubMed

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41
Alterations in CNS Activity Induced by Botulinum Toxin Treatment in Spasmodic Dysphonia: An H[subscript 2][superscript 15]O PET Study
2006-10-01

Speech-related changes in regional cerebral blood flow (rCBF) were measured using H[subscript 2][superscript 15]O positron-emission tomography in 9 adults with adductor spasmodic dysphonia (ADSD) before and after botulinum toxin (BTX) injection and 10 age- and gender-matched volunteers without neurological disorders. Scans were acquired at rest and during ...

ERIC Educational Resources Information Center

42
Abnormal Structure-Function Relationship in Spasmodic Dysphonia.
2011-06-10

Spasmodic dysphonia (SD) is a primary focal dystonia characterized by involuntary spasms in the laryngeal muscles during speech production. Although recent studies have found abnormal brain function and white matter organization in SD, the extent of gray matter alterations, their structure-function relationships, and correlations with symptoms remain ...

PubMed

43
Systems architecture for quantification of dynamic myoelectric and kinematic activity of the human vocal tract.
1990-11-01

This paper describes a systems architecture useful for scientific investigations that require the acquisition and analysis of multiple, time-synchronous signals in large volume. The architecture has recently been developed by this group to enhance our capability to research and quantify central nervous system function in the production of normal and pathologic speech. The architecture utilizes ...

PubMed

44
Nonlinear dynamic mechanism of vocal tremor from voice analysis and model simulations
2008-09-01

Nonlinear dynamic analysis and model simulations are used to study the nonlinear dynamic characteristics of vocal folds with vocal tremor, which can typically be characterized by low-frequency modulation and aperiodicity. Tremor voices from patients with disorders such as paresis, Parkinson's disease, hyperfunction, and adductor spasmodic dysphonia show ...

NASA Astrophysics Data System (ADS)

45
Development of a speech treatment program for a client with essential vocal tremor.
2011-04-13

Vocal tremor is characterized by involuntary rhythmic modulations of pitch and loudness and is best perceived during sustained phonation of vowels. It is most often present in individuals affected by neurogenic disorders such as Parkinson's disease, amyotrophic lateral sclerosis, spinal muscular dystrophy, spasmodic dysphonia, and essential tremor. Vocal ...

PubMed

46
Brain studies may alter long-held concepts about likely causes of some voice disorders
1989-02-17

Two voice disorders long considered to be psychological problems, stuttering and spasmodic dysphonia, have been shown in many persons to have a neurophysiological basis. Investigators at the 155th national meeting of the American Association for the Advancement of Science, in San Francisco, described their findings, which are based on new analytic ...

Energy Citations Database

47
High-throughput mutational analysis of TOR1A in primary dystonia
2009-03-11

BackgroundAlthough the c.904_906delGAG mutation in Exon 5 of TOR1A typically manifests as early-onset generalized dystonia, DYT1 dystonia is genetically and clinically heterogeneous. Recently, another Exon 5 mutation (c.863G>A) has been associated with early-onset generalized dystonia and some ?GAG mutation carriers present with late-onset focal dystonia. The aim of this study was to identify ...

PubMed Central

48
Adult-onset dystonia.
2011-01-01

Dystonia is defined as involuntary sustained muscle contractions producing twisting or squeezing movements and abnormal postures. The movements can be stereotyped and repetitive and they may vary in speed from rapid to slow; sustained contractions can result in fixed postures. Dystonic disorders are classified into primary and secondary forms. Several types of adult-onset primary dystonia have ...

PubMed

49
Abnormalities of sensorimotor integration in focal dystonia: a transcranial magnetic stimulation study.
2001-03-01

It has been postulated that sensorimotor integration is abnormal in dystonia. We investigated changes in motor cortical excitability induced by peripheral stimulation in patients with focal hand dystonia (12 patients with hand cramps) and with cervical dystonia (nine with spasmodic torticollis) compared with 16 age-matched normal controls. Motor evoked potentials (MEP) to ...

PubMed

50
Clinical and laboratory characteristics of focal laryngeal dystonia: study of 110 cases.
1988-06-01

Spastic dysphonia is a syndrome often producing a strain-strangle voice. We have previously classified most of these patients as having focal laryngeal dystonia, a disorder of central motor processing. In a study of 1,280 cases of dystonia registered at the Dystonia Clinical Research Center at the Columbia-Presbyterian Medical Center, we found 110 patients who had vocal cord ...

PubMed

51
An fMRI study of whispering: the role of human evolution in psychological dysphonia.
2011-04-08

Humans are the only species known to use whispering for communication, and humans are also the only species known to suffer from functional (psychological) aphonia, a condition in which only whispered and not vocalized speech can be produced. Thus, whispering is uniquely a human function and psychological aphonia is uniquely a human dysfunction; both can be considered to result from human ...

PubMed

52
[Comparative radiological study between spasmodic torticollis and Parkinson's disease. Notes on the etiology of spasmodic torticollis].
1975-03-01

The comparative clinic-radiological study between 45 patients with spasmodic torticollis and the same amount of patients with either essential Parkinsonism or tremor is reported. The study was based mainly on the alterations verified by plain roentgenograms and pneumoencephalography. The comparison between the findings obtained on both groups led the authors to conclude that ...

PubMed

53
Spasmodic Torticollis: Treatments

... a botulinum toxin Type B manufactured by Solstice Neurosciences) or XEOMIN�, (a botulinum toxin Type A manufactured ...

MedlinePLUS

54
Sporadic adult onset primary torsion dystonia is a genetic disorder by the temporal discrimination test.
2011-08-11

Adult-onset primary torsion dystonia is an autosomal dominant disorder with markedly reduced penetrance; patients with sporadic adult-onset primary torsion dystonia are much more prevalent than familial. The temporal discrimination threshold is the shortest time interval at which two stimuli are detected to be asynchronous and has been shown to be abnormal in adult-onset primary torsion dystonia. ...

PubMed

55
Proteomic Changes in Rat Thyroarytenoid Muscle Induced by Botulinum Neurotoxin Injection
2008-05-01

Botulinum neurotoxin (BoNT) injection into the thyroarytenoid (TA) muscle is a commonly performed medical intervention for adductor spasmodic dysphonia. The mechanism of action of BoNT at the neuromuscular junction is well understood, however, aside from reports focused on myosin heavy chain isoform abundance, there is a paucity of data addressing the ...

PubMed Central

56
A qualitative study of interference with communicative participation across communication disorders in adults.
2011-08-01

PURPOSE: To explore the similarities and differences in self-reported restrictions in communicative participation across different communication disorders in community-dwelling adults. Methods Interviews were conducted with 44 adults representing seven different medical conditions: spasmodic dysphonia, multiple sclerosis, stroke, stuttering, Parkinson's ...

PubMed

57
Botulinum Toxin
2011-05-15

... The earliest symptoms of botulism typically include visual disturbances, followed by dysphagia, dysphonia, and dysarthria, reflecting an especially ...

DTIC Science & Technology

58
Vascular catastrophe following the Dandy McKenzie operation for spasmodic torticollis.
1984-09-01

Delayed brain stem ischaemia following operation for spasmodic torticollis, is described. The mechanism for this catastrophe is considered and a hypothesis proposed which might allow its prediction and prevention. The overall results, the side and complications of this operation are summarised.

PubMed Central

59
Beneficial effect of sodium valproate and baclofen in spasmodic torticollis. A case report.
1984-01-14

A 47-year-old man of Irish descent was severely disabled by idiopathic spasmodic torticollis. Sodium valproate (Epilim) and baclofen (Lioresal) in combination provided marked relief maintained for over 6 months. No adverse or toxic effects were recorded during treatment. This is believed to be the first report in the literature on the efficacy of this drug combination in the ...

PubMed

60
Mechanism of Action of Botulinum Neurotoxin and Overview of ...
2011-05-14

... Signs and symptoms of intoxication, consisting of dysphagia, dysphonia, dizziness, headache, and blurred vision, were observed3 days later. ...

DTIC Science & Technology

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61
Chemical and Biological Defense: DOD Needs to Clarify ...
2001-10-01

... Ptosis, generalized weakness, dizziness, dry mouth and throat, blurred vision and diplopia, dysarthria, dysphonia, and dysphagia followed by ...

DTIC Science & Technology

62
Abstracts of Current Literature

... neurotoxicity, including respiratory failure (Pao2 45 mm Hg), dysphagia, ptosis, diplopia, and dysphonia. The high-dose group ( ... ...

NBII National Biological Information Infrastructure

63
............................................................... ................................................................................................................................

trauma may present with cough, dysphonia, hoarseness, stridor, hematemesis, hemoptysis and dysphagia and pressure differentials between arms, dysphagia, and chest pain, especially radiating to the back

E-print Network

64
Hip Abductor Defect Repair by Means of a Vastus Lateralis Muscle Shift.
2011-09-01

Scarring or detachment of the hip abductors, particularly of the gluteus medius, from their insertion may lead to severe abductor weakness, recurrent dislocations, pain, and diminished quality of life. We performed a retrospective study to evaluate whether vastus lateralis shift is associated with satisfactory results and low rate of complications. Eleven ...

PubMed

65
Recurrent dysphonia and acitretin.
2005-11-07

We report the case of a woman complaining of dysphonia while she was treated by acitretin. Her symptoms totally regressed after drug withdrawal and reappeared when acitretin was reintroduced. To our knowledge, this is the first case of acitretin-induced dysphonia. This effect may be related to the pharmacological effect of this drug on mucous membranes. ...

PubMed

66
Intensified Voice Therapy: A New Model for the Rehabilitation of Patients Suffering from Functional Dysphonias
2009-12-01

The objective of this study was to evaluate a new intervention for chronic dysphonias, consisting of a 2-week outpatient treatment period using intensified voice therapy combined with elements of physical medicine, including physiotherapy (orthotherapy, detonisation and training of the trunk muscles, respiratory therapy and others), manual therapy (mobilization of the cervical ...

ERIC Educational Resources Information Center

67
Post Marketing Surveillance Study of Dysport
2007-09-12

Blepharospasm; Hemifacial Spasm; Cervical Dystonia; Spasmodic Torticollis; Cerebral Palsy; Muscle Spasticity; Cerebrovascular Accident; Equinus Deformity; Facial Hyperdynamic Lines

ClinicalTrials.gov

68
Shortfalls of the American Academy of Otolaryngology-Head and Neck Surgery's Clinical practice guideline: Hoarseness (Dysphonia).
2010-08-01

The Clinical Practice Guideline (CPG) on hoarseness (dysphonia) has several shortcomings that undermine its initial intent to improve the care of patients with dysphonia. The purpose of this document is to identify and comment on those shortcomings. The guideline authors made curious and unsupported policy recommendations in some areas, such as the ...

PubMed

69
Is dysphonia permanent or temporary after anterior cervical approach?
2007-09-08

The rate, causes and prognosis of dysphonia after anterior cervical approach (ACA) were investigated in our clinical series. During a 10-year interval, 235 consecutive patients with cervical disc disease underwent surgical treatment using anterior approach. Retrospective chart reviews showed recurrent laryngeal nerve (RLN) injury in 3 (1.27%) patients. All three patients were ...

PubMed Central

70
The recurrent laryngeal nerve in spastic dysphonia. A light and electron microscopic study.

Sections of right or left recurrent laryngeal nerve (RLN), removed from patients with spastic dysphonia (SD) at the time of surgery, were studied using light and electron microscopy and were compared with control RLNs. In both groups, small, medium and large-sized myelinated nerve fibres were found in the RLN. Furthermore, numerous unmyelinated axons intermingled with the ...

PubMed

71
Dysphonia: A New Addition to Jellyfish Envenomation Syndromes

... before disappearing after a week. The only systemic symptom was an overnight headache appearing a few hours after the sting. A biopsy of chest skin obtained 4 days ... ...

NBII National Biological Information Infrastructure

72
[Diagnosis and therapy of hip abductor insufficiency after hip arthroplasty].
2011-06-01

Abductor insufficiency after hip arthroplasty is a difficult and challenging problem whereby conservative therapy is often insufficient and surgical therapy is known to have failures with re-ruptures. Alternative approaches and arthroscopic surgery are proposed but in many cases they do not fulfill the expectations of patients.Our experience with temporary explantation of ...

PubMed

73
The relationship between hip abductor muscle strength and iliotibial band tightness in individuals with low back pain
2010-01-13

BackgroundShortening of the iliotibial band (ITB) has been considered to be associated with low back pain (LBP). It is theorized that ITB tightness in individuals with LBP is a compensatory mechanism following hip abductor muscle weakness. However, no study has clinically examined this theory. The purpose of this study was to investigate the muscle imbalance of hip ...

PubMed Central

74
The Influence of Load Carrying Methods on Gait of Healthy ...
2001-05-01

... 100 millimeters (the most intense pain), was used ... abductors, and adductors Step 3. Muscles from Step 2 ... r2) of Shoulder Girdle Muscle Strength and ...

DTIC Science & Technology

75
Resources
2011-08-30

Act 42 U.S.C. 5771 Requires law enforcement to enter complete descriptions of missing children into NCIC, even if the abductor has not been charged with a crime National Child...

Science.gov Websites

76
Familial congenital laryngeal abductor paralysis: different expression in a family with one male and three females affected.
1990-11-01

A brother and two sisters of remotely consanguineous parents had congenital laryngeal abductor paralysis and moderate mental retardation. In the two older sibs, mental deficiency could have resulted from birth asphyxia, but the youngest girl was already microcephalic at birth and had no apparent asphyxia. The mother, who was healthy and of normal intelligence, was found on ...

PubMed Central

77
Nonlinear dynamic analysis of disordered voice: the relationship between the correlation dimension (D2) and pre-/post-treatment change in perceived dysphonia severity.
2009-06-07

The purpose of this study was to evaluate the clinical utility of nonlinear dynamic analysis methods, including phase space portraits and measures of the correlation dimension (D(2)) to predict pre- versus post-treatment change in perceived dysphonia severity in a group of 88 patients with muscle tension dysphonia (MTD). Pre- and posttreatment vowel ...

PubMed

78
Dysphonia Detected by Pattern Recognition of Spectral Composition.
1991-12-01

This study analyzed production of a long vowel sound within Finnish words by normal or dysphonic voices, using the Self-Organizing Map, the artificial neural network algorithm of T. Kohonen which produces two-dimensional representations of speech. The method was found to be both sensitive and specific in the detection of dysphonia. (Author/JDD)

ERIC Educational Resources Information Center

79
Southern Yellow Pine Sapwood Panels with Copper Sulphonate.
1964-01-01

This report presents the results of seawater immersion tests. After six and one-half years exposure, unpainted panels treated with Copper Sulphonate showed remarkable resistance to marine borer activity. There were spasmodic evidences of embryonic Bankia ...

National Technical Information Service (NTIS)

80
Calcaneo-Scaphoid Coalition
1933-02-01

Calcaneo-scaphoid coalition occurs in a number of forms, having one feature in common, namely, a skeletal abnormality of the calcaneo-scaphoid gap. The condition is congenital, but nothing is known of its causation. Ranking at first as merely an anatomical curiosity, it was later recognized to be frequently associated with spasmodic flat-foot. Probably 25% of all cases of ...

PubMed Central

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81
Beijing cough: a case report
2008-05-12

Case PresentationUpon arrival in Beijing, China from London, England in 2008 a previously healthy 56-year old man developed a regular spasmodic cough for the duration of his stay in the city.

PubMed Central

82
Somatosensory evoked potentials in the ventrolateral thalamus.
1986-01-01

Within the target area (VL) used for the stereotactic treatment of parkinsonian tremor and spasmodic torticollis, electrical stimulation as well as recording of somatosensory evoked potential (SEP) was performed. The effects of stimulation in the target area are facilitation of muscle tone showing some degree of somatotopic distribution. The recorded SEPs indicate a projection ...

PubMed

83
Laser diffractometry of erythrocyte deformation under hypo-osmotic hemolysis
2000-11-01

The experimental research and theoretical modeling of average radius and refractive index change of spherocytes aggregation of ill and well people under the swelling in solutions of various osmolarity and by taking into account the rigidity of the erythrocyte membrane have been carried out. The spasmodic character of decrease of spherocyte radius has been discovered for the ...

NASA Astrophysics Data System (ADS)

84
Understanding of Hands and Task Characteristics for Development of Biomimetic Robot Hands

targeted to obtain the activities of the Extensor Digitorium (ED), Abductor Pollicis Longus (APL), Flexor, the flexor digitorum superficialis (FDS), an extrinsic flexor muscle, is normally connected to the MCP joints Digitorum Superficialis (FDS), Dorsal Interosseous (DI), Abductor Pollicis Brevis (APB), Extensor Pollicis

E-print Network

85
Fig. 1. Experimental setup. Abstract- This paper describes a real-time isometric pinch

muscles during the pinch force generation. Extensor Digitorium (ED), Abductor Pollicis Longus (APL), Flexor Digitorum Superficialis (FDS), Dorsal Interosseous (DI), Abductor Pollicis Brevis (APB), Flexor Pollicis Brevis (FPB), and Adductor Pollicis (AP). To obtain the seven target muscles' activities, seven

E-print Network

86
Effects of Multi-modal Physiotherapy, Including Hip Abductor Strengthening, in Patients with Iliotibial Band Friction Syndrome
2008-10-10

Purpose:The purposes of this study were to quantitatively examine hip abductor strength in patients presenting with iliotibial band friction syndrome (ITBFS) and to determine whether a multi-modal physiotherapy approach, including hip abductor strengthening, might play a role in recovery.Method:Our observational, pretest�posttest study is one of the ...

PubMed Central

87
Direct Comparison of the Task-Dependent Discharge of M1 in Hand Space and Muscle Space

superficialis; EDC, extensor digitorum communis; E45, extensor digiti 4,5; AbPL, abductor pollicis longus; Ad communis and quarti et quinti proprius (EDC, E45); abductor pollicis longus (AbPL); adductor pollicis (Ad, triceps; Bic, biceps; Pro, pronator teres; Brd, brachioradialis; FCR, flexor carpi radialis; FCU, flexor

E-print Network

88
Comparison Study of Biosignal based Computer Interfaces Based on Fitts' Law Paradigm

), the extensor carpi radialis (ECR), the extensor carpi ulnaris (ECU), and the abductor pollicis longus (APL), the extensor carpi radialis (ECR), the extensor carpi ulnaris (ECU), and the abductor pollicis longus (APL related to the production of the wrist movements above were selected: the flexor carpi ulnaris (FCU

E-print Network

89
Activation Patterns of the Thumb Muscles During Stable and Unstable

surface were inserted into flexors pollicis longus (FPL) and brevis (FPB), extensors pollicis longus (EPL) and brevis (EPB), abductors pollicis longus (APL) and brevis (APB), opponens pollicis (OPP), adductor that the highest magnitudes of force can be accurately directed. Abductor pollicis brevis and extensor pollicis

E-print Network

90
Quantitative abductor pollicis brevis strength testing: reliability and normative values.
2000-07-01

We conducted this study to establish reliability and normative values for abductor pollicis brevis strength. A portable microprocessor-controlled hand-held device was used for testing. Twelve healthy subjects were used for intrarater and interrater reliability testing. Intraclass correlation coefficients were 0.92 for intrarater testing and 0.89 for interrater reliability. ...

PubMed

91
Late repair of abductor avulsion after the transgluteal approach for hip arthroplasty.
2009-03-17

The abductor release sometimes does not heal after a transgluteal approach for hip arthroplasty. Factors influencing the success of subsequent repair are unclear. We used magnetic resonance imaging (MRI) to compare the condition of the gluteus medius with clinical outcome after late repair of abductor dehiscence in 12 total hip patients. Evaluation ...

PubMed

92
A reproducible and inexpensive method of measuring hip abductor strength.

The evaluation of hip abductor strength is useful in assessing of the outcome of hip surgery. Hand-held dynamometers are available, but they are less reliable in assessing hip abductor strength than some other muscle groups. We describe a new device designed to measure hip abductor strength, which is practical in a clinical setting. A ...

PubMed

93
Voice disorders (dysphonia) in public school female teachers working in Belo Horizonte: prevalence and associated factors.
2007-11-05

The objective of this study is to establish the prevalence of dysphonia and associated factors in public school female teachers working in Belo Horizonte. This cross-sectional study was conducted on a random sample of schools between May 2004 and July 2005. There were 2103 elementary education daytime teachers from 83 schools included in the study. Self-applied questionnaires ...

PubMed

94
Surgical Technique: Transfer of the Anterior Portion of the Gluteus Maximus Muscle for Abductor Deficiency of the Hip.
2011-07-28

BACKGROUND: Loss of the abductor portions of the gluteus medius and gluteus minimus muscles due to THA causes severe limp and often instability. DESCRIPTION OF TECHNIQUE: To minimize the symptoms of limp and instability, the anterior � of the gluteus maximus was transferred to the greater trochanter and sutured under the vastus lateralis. A separate posterior flap was ...

PubMed

95
Is the Internal Rotation Lag Sign a Sensitive Test for Detecting Hip Abductor Tendon Ruptures after Total Hip Arthroplasty?
2011-04-17

IntroductionTotal hip arthroplasty (THA) is one of the most frequently performed procedures in orthopaedics and weakness of external rotators is often recognized thereafter. However, the etiology of lateral hip pain is multifaceted. For the diagnosis of abductor tendon rupture, magnetic resonance imaging (MRI) is the gold standard. As not every patient can be subjected to MRI, ...

PubMed Central

96
been found for pre-gastrula embryos, the beta4 gain and loss-of function phenotypes suggest potentially novel roles for the beta4

defects (dysphonia) and swallowing defects (dysphagia) have been implicated in several congenital diseases

E-print Network

97
Functional Voice Outcomes After Thyroidectomy: An Assessment of the Dsyphonia Severity Index (DSI) After Thyroidectomy.
2010-01-01

The Dysphonia Severity Index (DSI) is an objective multiparametric acoustic calculation of vocal function; however, its changes after thyroidectomy have not yet been described. Patient-reported symptoms, as well as auditory perceptual, acoustic, and video...

National Technical Information Service (NTIS)

98
Hereditary whispering dysphonia.
1985-03-01

An Australian family group is described where at least twenty members have inherited torsion dystonia and two siblings with an affected mother have similar clinical manifestations, but have also the biochemical and pathological changes found in Wilson's disease. Whispering dysphonia was the commonest presenting symptom, and a diagnosis of hysteria was invariably made if the ...

PubMed Central

99
Challenges and opportunities in the management of the aging voice.
2011-04-26

Presbyphonia, or age-related dysphonia, is a diagnosis of exclusion, and other comorbidities must be considered in a complete evaluation of elderly patients with dysphonia. The aging voice can have a significant effect on the quality of life of the patient. In addition to the molecular effects of aging on the laryngeal tissues, the etiology of presbyphonia ...

PubMed

100
The Rottinger approach for total hip arthroplasty: technique and review of the literature.
2011-08-01

The surgical approach utilized in total hip arthroplasty has been identified as a factor that may affect surgical outcomes. There have been many different approaches and modifications used since the procedure was popularized by Sir John Charnley. The popular approaches today can be grouped by their relationship to the trochanter (anterior or posterior), patient position, leg position for ...

PubMed

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101
Surgical repair of abductor hallucis muscle herniation: a case report.

Herniation of the abductor hallucis muscle has rarely been reported in the literature. This condition causes localized pain, especially while weight bearing, as a result of a complex cascade of biomechanical events directly related to loss of integrity of the medial wall of the foot. The authors present a case of a flexor retinaculum tear with subsequent herniation of the ...

PubMed

102
Stridor and focal laryngeal dystonia.
1992-02-22

Fibreoptic laryngoscopy in 6 patients with laryngeal stridor showed immobile vocal cords in a paramedian position but no other local cause. Thus a diagnosis of Gerhardt's syndrome, usually ascribed to paralysis of vocal-cord abductor muscles, was made in 3 patients who had no other signs or symptoms of dystonia, and in 3 patients who had multifocal dystonia. Electromyography ...

PubMed

103
Exploring Genetic and Environmental Effects in Dysphonia: A Twin Study
2009-02-01

Purpose: To explore the existence of genetic effects as well as the interaction between potential genetic effects and a voice-demanding occupation on dysphonia. Method: One thousand seven hundred and twenty-eight Finnish twins (555 male; 1,173 female) born between 1961 and 1989 completed a questionnaire concerning vocal symptoms and occupation. The zygosity determination ...

ERIC Educational Resources Information Center

104
Increase of glucose consumption in basal ganglia, thalamus and frontal cortex of patients with spasmodic torticollis
1994-05-01

The pathophysiology of spasmodic torticollis, a focal dystonia involving neck muscles, is still unclear. Positron emission tomography (PET) studies showed either an increase as well as a decrease of regional cerebral metabolic rate of glucose (rCMRglu) in basal ganglia. In the present study, [18F]FDG and PET was used to measure rCMRglu in 10 patients with ...

Energy Citations Database

105
Coronary artery vasospasm: the likely immediated cause of acute myocardial infarction.
1979-04-01

Features of infarction can be divided into two types--the spasmodic and the mechanical. The former (pre-infarct angina and emotional factors in infarction) seem readily explainable by spasm, and are similar to the findings in angina which prompted Heberden to consider angina as spasmodic. The mechanical features of infarction (association with thrombosis ...

PubMed Central

106
Family Abductors: Descriptive Profiles and Preventive Interventions.
2001-01-01

Parental abduction encompasses a broad array of illegal behaviors that involve one parent taking, detaining, concealing, or enticing away his or her child from the parent having custodial access. When the abducting parent intends to permanently alter cust...

National Technical Information Service (NTIS)

107
Electromyographic analysis of hip abductor exercises performed by a sample of total hip arthroplasty patients.
2008-08-30

Weakness of the hip abductors after total hip arthroplasty may result in pain and/or functional limitation. Non-weight-bearing (NWB) exercises are often performed to target the hip abductors; however, muscle activation of NWB exercises has not been compared to weight-bearing (WB) exercises. Our purpose was to evaluate gluteus medius activation during 2 WB ...

PubMed

108
Correspondence: Dr Jon H. Kaas, 301 Wilson Hall, Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA. Tel.

were placed in abductor pollicis brevis, opponens digiti minimi, extensor carpi ulnaris, and flexor pollicis longus. For the muscles mediating proximal forelimb movements, injections were placed in shoulder

E-print Network

109
Core Stability and Its Relationship to Lower

concluded that strength and endurance training of the hip abductors and external ro- tators should- strings, and abdominal muscles to resist external moments at the hip and knee. More recently, Ford et al44 is the ability of the lumbopelvic hip complex to prevent buckling and to return to equilibrium after perturbation

E-print Network

110
Adductors, abductors, and the evolution of archosaur locomotion

... skeleton. II. information from newly collected specimens of Velociraptor mongoliensis. American Museum Novitates 3282:1�45. Novas, ... Marasuchus) modified from Sereno and Arcucci 1994, Allosaurus, Veloci...

NBII National Biological Information Infrastructure

111
Hypertrophy of the abductor digiti minimi muscle simulating a localised soft tissue mass.
2007-12-11

Soft tissue tumours of the foot are rare and often present a difficult clinical and diagnostic situation. We report of a 15-year-old male with a painless swelling at the lateral margin of the left foot. After X-ray and MRI an excisional biopsy was performed. Histology revealed true muscle hypertrophy without myopathic or degenerative changes, consistent with the diagnosis of congenital hypertrophy ...

PubMed

112
Toward the Development of an Objective Index of Dysphonia Severity: A Four-Factor Acoustic Model
2005-12-01

During assessment and management of individuals with voice disorders, clinicians routinely attempt to describe or quantify the severity of a patient's dysphonia. This investigation used acoustic measures derived from sustained vowel samples to predict dysphonia severity (as determined by auditory-perceptual ratings), for a diverse set of voice samples ...

ERIC Educational Resources Information Center

113
Describing pediatric dysphonia with nonlinear dynamic parameters
2008-10-22

ObjectiveNonlinear dynamic analysis has emerged as a reliable and objective tool for assessing voice disorders. However, it has only been tested on adult populations. In the present study, nonlinear dynamic analysis was applied to normal and dysphonic pediatric populations with the goal of collecting normative data. Jitter analysis was also applied in order to compare nonlinear dynamic and ...

PubMed Central

114
Contribution of Hip Abductor Strength to Physical Function in Patients With Total Knee Arthroplasty
2011-02-01

BackgroundInvestigating modifiable factors that contribute to functional limitations in patients with total knee arthroplasty (TKA) may guide changes in rehabilitation protocols and improve functional outcomes. Whereas quadriceps muscle weakness has been demonstrated to contribute to functional limitations in TKA, the role of hip abductor weakness has not received ...

PubMed Central

115
Muon spin relaxation study of protonic superionic conductor CsHSO(sub 4).
1989-01-01

The protonic superionic conductor CsHSO(sub 4) has been studied by (mu)SR over the range of temperatures 15-440 K. The first successful observation of superionic phase transition by the (mu)SR method is reported. A spasmodic change in relaxation rate and ...

National Technical Information Service (NTIS)

116
De Novo Exon Duplication in a New Allele of Mouse Glra1 (Spasmodic)
2006-12-01

The novel neurological mutant Cincinatti arose by genomic duplication of exon 5 in the glycine receptor gene Glra1. The mutant transcript results in premature protein truncation. A direct repeat of the pentamer GGGGC is present adjacent to the breakpoints and may have mediated the duplication event by a replication slippage mechanism.

PubMed Central

117
[Dysphonia and cacosmia in a worker in sterilized rooms].

A 39 year male pharmaceutical worker employed in a clean-room developed in 2003 acute dysphonia after environmental disinfection with glutaric aldehyde and isopropyl alcohol. Laryngoscopic examination showed glottis edema; the syndrome healed after a cycle of cortisone. In subsequent years, withdrawal from exposure to irritating chemicals was observed. The worker, however, ...

PubMed

118
Dysphonia
2007-03-02

Dysphonia is a program about impaired voice quality or hoarseness (i.e. dysphonia) mainly due to organic diseases of the larynx, including clinical histories, voice samples, microlaryngoscopic images, examination techniques, diagnosis, and treatment. The program aims to facilitate learning of the management of in the first hand organic voice disorders by ...

NSDL National Science Digital Library

119
An Examination of Surface EMG for the Assessment of Muscle Tension Dysphonia.
2011-08-31

OBJECTIVES: Muscle tension dysphonia (MTD) is the pathological condition in which an excessive tension of the (para)laryngeal musculature leads to a disturbed voice. Surface electromyography (sEMG) was used to investigate differences in extralaryngeal muscles' tension in patients with MTD compared with normal speakers. sEMG was examined as a diagnostic tool to differentiate ...

PubMed

120
Laryngeal dysfunction in Amyotrophic Lateral Sclerosis: a review and case report
2001-11-13

BackgroundLaryngeal dysfunction can be a salient feature in the clinical symptomatology of speakers diagnosed with Amyotrophic Lateral Sclerosis (ALS). In addition to dysphonia, swallowing function is also disrupted. This paper reviews what is known about laryngeal dysfunction resulting from ALS.ResultsPresented is a case report of a female, diagnosed with ALS, whose initial ...

PubMed Central

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121
FURTHER STUDY OF SPASTIC DYSPHONIA
1962-08-01

Seven women and two men with spastic dysphonia, ranging in age from 20 to 59 years, were studied to determine the cause and the means of development of the condition. The patients were examined by a laryngologist and, when feasible, by a psychiatrist or other medical specialist for coordination and corroboration of the diagnosis. Psychiatric observations were significant. A ...

PubMed Central

122
EMG biofeedback treatment of pediatric hyperfunctional dysphonia.
1991-06-01

A 9-year-old boy with a long history of impaired communication resulting from hyperfunctional dysphonia and vocal nodules had proven to be unresponsive to traditional voice therapy. In this study, he engaged in biweekly visual EMG biofeedback training to reduce laryngeal muscle tension. In a multiple baseline design across two responses with changing criteria, results ...

PubMed

123
Assessment of dysphonia due to benign vocal fold lesions by acoustic and aerodynamic indices: a multivariate analysis.
2010-10-15

The goal was to identify acoustic and aerodynamic indices that allow the discrimination of a benign organic dysphonic voice from a normal voice. Fifty-three patients affected by dysphonia caused by vocal folds benign lesions, and a control group were subjected to maximum phonation time (MPT) measurements, GRB perceptual evaluations and acoustic/aerodynamic tests. All analyzed ...

PubMed

124
The effect of abductor muscle and anterior-posterior hip contact load simulation on the in-vitro primary stability of a cementless hip stem
2010-06-24

BackgroundIn-vitro mechanical tests are commonly performed to assess pre-clinically the effect of implant design on the stability of hip endoprostheses. There is no standard protocol for these tests, and the forces applied vary between studies. This study examines the effect of the abductor force with and without application of the anterior-posterior hip contact force in the ...

PubMed Central

125
Sonographic Evidence for the Absence of Abductor Pollicis Longus, Extensor Pollicis Longus, and Brevis.
2010-04-16

Complete absence or variations of extensor pollicis brevis and abductor pollicis longus; absence of the extrinsic extensors, abductor pollicis longus, thenar muscles along with congenital hypoplasia of the thumb; absence of flexor pollicis brevis and abductor pollicis brevis; and bilateral absence of extensor pollicis have been ...

PubMed

126
Three-dimensional anatomic characterization of the canine laryngeal abductor and adductor musculature.
2000-05-01

The biomechanics of vocal fold abduction and adduction during phonation, respiration, and airway protection are not completely understood. Specifically, the rotational and translational forces on the arytenoid cartilages that result from intrinsic laryngeal muscle contraction have not been fully described. Anatomic data on the lines of action and moment arms for the intrinsic laryngeal muscles are ...

PubMed

127
Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse.
2011-03-08

Inhibitory glycine receptors (GlyRs) are pentameric ligand gated ion channels composed of ? and ? subunits assembled in a 2:3 stoichiometry. The ?1/?heteromer is considered the dominant GlyR isoform at 'native' adult synapses in the spinal cord and brainstem. However, the ?3 GlyR subunit is concentrated in the superficial dorsal horn (SDH: laminae I-II), a spinal cord region important for ...

PubMed

128
REM sleep behavior disorder and vocal cord paralysis in Machado-Joseph disease.
2003-10-01

We evaluated the occurrence of REM sleep behaviour disorder (RBD) and vocal cord abductor paralysis (VCAP) in a group of 9 Machado-Joseph disease (MJD) patients. RBD was diagnosed by clinical history plus audiovisual polysomnography in 4 men and 1 woman (55%). While dreaming, 4 fell out of the bed and the other injured his arms. Laryngoscopy detected bilateral VCAP in 1 ...

PubMed

129
Anatomic Variations of the First Extensor Compartment and Abductor Pollicis Longus Tendon in Trapeziometacarpal Arthritis
2009-10-16

Anatomic variation of the trapeziometacarpal joint stabilizing structures is one of the concepts proposed to explain the pathogenesis of trapeziometacarpal arthritis. We undertook this study to test the hypothesis that septation of the first extensor compartment or variation of the abductor pollicis longus (APL) tendon (supernumerary insertions) are more frequently associated ...

PubMed Central

130
[Paracoccidiodomycosis, disseminated chronic form--case report].

Case report of paracoccidiodomycosis Chronic Form, adult type, with genital lesions and residual form presented as dysphagia and dysphonia at the same patient. Diagnosis accomplished by direct examination of clinical specimens, in this case cutaneous lesions. After specific treatment there was regression of lesions and symptoms had disappeared. PMID:14685642

PubMed

131
The Prevalence of Dysphonia, Its Association With Immunomediated Diseases And Correlation With Biochemical Markers.
2011-03-24

INTRODUCTION: Patients with autoimmune diseases may suffer from hoarseness and voice disorders because of anatomical and functional alterations. OBJECTIVES: To assess the prevalence of dysphonia in rheumatic patients and its impact on their quality of life (QOL). To analyze the association of voice disorders in patients with rheumatoid arthritis (RA), systemic lupus ...

PubMed

132
The Acoustic Voice Quality Index: toward improved treatment outcomes assessment in voice disorders.
2009-12-23

Voice practitioners require an objective index of dysphonia severity as a means to reliably track treatment outcomes. To ensure ecological validity however, such a measure should survey both sustained vowels and continuous speech. In an earlier study, a multivariate acoustic model referred to as the Acoustic Voice Quality Index (AVQI), consisting of a weighted combination of 6 ...

PubMed

133
Electroglottography in elderly patients with vocal-fold palsy.
2008-05-27

The incidence of dysphonia in healthy elderly people is high. In individuals with iatrogenic vocal-fold paresis following thyroid surgery, serious aggravation of vocal skills contributes to impaired quality of life and requires proper management. Electroglottography is a common method for providing noninvasive measurements of glottal activity, yielding reliable indicators of ...

PubMed

134
Dysphonia as a primary manifestation in myasthenia gravis (MG): a retrospective review of 7 cases among 1520 MG patients.
2007-04-26

Myasthenia gravis (MG) is an autoimmune disorder of neuromuscular transmission, usually recognized with ocular complaints or generalized muscle weakness. However, among the 1520 MG cases that had been diagnosed and treated in our hospital in the last 15 years (1990-2005), we have identified 7 MG patients whose initial and prominent complaint was dysphonia and all had been ...

PubMed

135
Articulatory Changes in Muscle Tension Dysphonia: Evidence of Vowel Space Expansion Following Manual Circumlaryngeal Therapy
2008-12-01

In a preliminary study, we documented significant changes in formant transitions associated with successful manual circumlaryngeal treatment (MCT) of muscle tension dysphonia (MTD), suggesting improvement in speech articulation. The present study explores further the effects of MTD on vowel articulation by means of additional vowel acoustic measures. Pre- and post-treatment ...

ERIC Educational Resources Information Center

136
[CO2 laser cordectomy: analysis of morpho-functional results].
2000-04-01

The authors have conducted a study of a large sampling of subjects who had undergone different types of cordectomy. The purpose of this study has been to analyze the anatomo-functional variables encountered with such procedures. In particular, the following were studied: post-surgical vocal recovery; type of glottic sphincter scarring, particularly as related to the extent of surgical excision; ...

PubMed

137
The twisting of filament that resulted in a solar flare
1994-10-01

Based mainly on filtergrams ofH? line center and various offbands and supplemented with measurements of the CIV 1548 line, we analyzed the evolution of a filament during a period of 15 minutes prior to the eruption of the flare of 1980 June 25 in the active region AR 2522. The filament underwent three spasmodic twistings of increasing size which finally led to its disruption ...

NASA Astrophysics Data System (ADS)

138
Spasmodic tremor and possible magma injection in long valley caldera, eastern california.
1983-03-25

Intensive microearthquake swarms with the appearance of volcanic tremor have been observed in the southwest part of Long Valley caldera, southeastern California. This activity, possibly associated with magma injection, began 6 weeks after several strong (magnitude 6+) earthquakes in an area south of the caldera and has continued sporadically to the present time. The earthquake sequence and ...

PubMed

139
Spasmodic tremor and possible magma injection in Long Valley caldera, eastern California
1983-03-25

Intensive microearthquake swarms with the appearance of volcanic tremor have been observed in the southwest part of Long Valley caldera, southeastern California. This activity, possibly associated with magma injection, began 6 weeks after several strong (magnitude 6+) earthquakes in an area south of the caldera and has continued sporadically to the present time. The earthquake sequence and ...

Energy Citations Database

140
MOLECULAR AND CELLULAR BIOLOGY, Aug. 2006, p. 5728�5734 Vol. 26, No. 15 0270-7306/06/$08.00 0 doi:10.1128/MCB.00237-06

oc- curring mouse startle disease mutants: spastic, spasmodic, and oscillator. The spastic mutant, GABA(A) receptor protein expression has been shown to be upregulated in spastic mice, which contain. Betz. 1992. Isoform-selective deficit of glycine receptors in the mouse mutant spastic. Neuron 8

E-print Network

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141
Achillea millefolium L. s.l. revisited: recent findings confirm the traditional use.
2007-01-01

Yarrow (Achillea millefolium L. s.l.) is traditionally used in the treatment of inflammatory and spasmodic gastro-intestinal disorders, hepato-biliary complaints and inflammation. Now we could show that the flavonoids mediated the antispasmodic properties of yarrow, whereas the dicaffeoylquinic acids caused the choleretic effects. Moreover, we observed an in vitro-inhibition ...

PubMed

142
Single-channel study of the spasmodic mutation alpha1A52S in recombinant rat glycine receptors.
2007-03-01

Inherited defects in glycine receptors lead to hyperekplexia, or startle disease. A mutant mouse, spasmodic, that has a startle phenotype, has a point mutation (A52S) in the glycine receptor alpha1 subunit. This mutation reduces the sensitivity of the receptor to glycine, but the mechanism by which this occurs is not known. We investigated the properties of A52S recombinant ...

PubMed

143
Single-channel study of the spasmodic mutation ?1A52S in recombinant rat glycine receptors
2007-05-15

Inherited defects in glycine receptors lead to hyperekplexia, or startle disease. A mutant mouse, spasmodic, that has a startle phenotype, has a point mutation (A52S) in the glycine receptor ?1 subunit. This mutation reduces the sensitivity of the receptor to glycine, but the mechanism by which this occurs is not known. We investigated the properties of A52S recombinant ...

PubMed Central

144
[Importance of the position of the greater trochanter].
1990-01-01

The position of the greater trochanter influences the mechanical stress of the hip joint, the extent of contraction of the gluteus medius and minimus muscles, and the mechanical stress of the femoral neck. A normal neck-shaft angle appears to achieve a compromise between a maximum lever arm of the abductor muscles and a maximum possibility of contraction. For the same length ...

PubMed

145
Reliability of measuring abductor hallucis muscle parameters using two different diagnostic ultrasound machines
2009-11-16

BackgroundDiagnostic ultrasound provides a method of analysing soft tissue structures of the musculoskeletal system effectively and reliably. The aim of this study was to evaluate within and between session reliability of measuring muscle dorso-plantar thickness, medio-lateral length and cross-sectional area, of the abductor hallucis muscle using two different ultrasound ...

PubMed Central

146
Muscles of Head (and Neck, in part) muscles of facial expression

brevus posterior (flexors, plantar flexors) superficial gastrocnemius (medial and lateral heads digitorum brevis extensor hallicis brevis deep dorsal interossei plantar (superficial to deep; lateral to medial) superficial plantar aponeurosis (most superficial) abductor digiti V flexor digitorum brevis

E-print Network

147
Ipsilateral Hip Abductor Weakness After Inversion Ankle Sprain
2006-01-01

Context: Hip stability and strength are important for proper gait mechanics and foot position during heel strike.Objective: To determine the relationships between hip muscle strength and chronic ankle sprains and hip muscle strength and ankle range of motion.Design: Ex post facto design with the uninvolved limb serving as the control.Setting: Laboratory.Patients or Other Participants: A total of ...

PubMed Central

148
Increased power generation in impaired lower extremities correlated with changes in walking speeds in sub-acute stroke patients.
2011-09-01

BACKGROUND: Establishing changes in net joint power in the lower extremity of patients during recovery of walking might direct gait training in early stroke rehabilitation. It is hypothesized that (1) net joint power in the lower extremity joints would increase in sub-acute stroke patients following gait rehabilitation, and (2) the improvements in net joint power would be significantly correlated ...

PubMed

149
Functional anatomy of the radial sesamoid bone in the giant panda (Ailuropoda melanoleuca).
1996-12-01

The function of the radial sesamoid bone (RS) in the giant panda (Ailuropoda melanoleuca) was examined by macroscopic study of RS-related bones and muscles. The RS was observed to be connected to the scapholunar and the 1st metacarpal bones. A joint cavity was present between the proximal surface of the RS and the distal area of the scapholunar bone but the RS possessed a fibrous joint connecting ...

PubMed Central

150
Early palsy of the sciatic nerve due to heterotopic ossification after surgery for fracture of the posterior wall of the acetabulum.
2009-02-01

We describe a patient in whom an initially intact sciatic nerve became rapidly encased in heterotopic bone formed in the abductor compartment after reconstruction of the posterior wall of the acetabulum following fracture. Prompt excision and neural release followed by irradiation and administration of indometacin resulted in a full neurological recovery and no recurrence 27 ...

PubMed

151
Biostat 208 Lab #7, 2/17/05 Lab Summary

.2 in unadjusted analysis; these include � age � log weight � alcohol and caffeine consumption, current smoking are associated with EEU, with only a few exceptions (history of nonspine fracture, use of etidronate, caffeine stand, use of arms to stand up, hip abductor strength, gait speed; poor health by self-report; caffeine

E-print Network

152
Author's personal copy Journal of Neuroscience Methods 187 (2010) 100�104

and extrinsic hand extensors included abductor pollicis longus (AbPL) and extensors carpi radialis brevis (ECRB (ED45), and carpi ulnaris (ECU). Wrist and extrinsic hand flexors included palmaris longus (PLPB), adductor pollicis (AdP), opponens pollicis (OP), and flexors pollicis brevis superficialis (FPBS

E-print Network

153
Anatomical Basis of Differences in Locomotor Behavior in Anolis Lizards: A Comparison Between Two Ecomorphs

... M. flexor digitorum longus pars profundus. 36. M. flexor carpi radialis. 37. M. pronator teres. 38. M. pronatoraccesorius. 39. M. extensor carpi ulnaris. 40. M. abductor pollicis longus. 41. M. extensor ca...

NBII National Biological Information Infrastructure

154
Abstract-This paper presents the development and per formance evaluation of a human-computer interface that en

. Then, for each muscle contraction, four muscles were selected by palpation: the flexor carpi ulnaris (FCU), the extensor carpi radialis (ECR), the ex- tensor carpi ulnaris (ECU), and the abductor pollicis longus (APL) [11]. Because quadriplegic patients (with a C7 and C8 functional level) can still weakly

E-print Network

155
8 Imaging Experiments Having completed the construction of the instrument and evaluated the most important

it is wrapped in black cloth in order to provide optical shielding. #12;159 Flexors Abductor pollicis longus Ulna on the left is a strain gauge used in finger flexor experiments. 8.3.1 Absolute images 8.3.1.1 Introduction in order to better represent the subtle variations in the absorption maps. #12;161 8.3.2 Finger flexor

E-print Network

156
291J. exp. Bioi.. 155, 291-304 (1991) Printed in Great Britain @ The Company of Biologists Limited 1991

the superficial region of the pectoral fin abductor superficialis muscle of common carp (Cyprinus carpio L-acclimation occur in other cyprinids, including common carp (Cyprinus carpio L.) and roach (Rutilus rutilusL.) (Heap of slow muscle myosin has also been investigated. Materials and methods Fish Common carp (Cyprinus carpio

E-print Network

157
"Intersection syndrome" of the foot: treated by endoscopic release of master knot of Henry.
2011-02-03

Intersection syndrome of the forearm is a painful condition in the area where the muscle bellies of the abductor pollicis longus and extensor pollicis brevis cross the common wrist extensors. A similar case of the foot with marked fibrosis at the interconnection of flexor hallucis longus and flexor digitorum tendons is reported and the fibrous interconnection was extended ...

PubMed

158
Hip Abductor Function and Lower Extremity Landing Kinematics: Sex Differences

Context: Rapid deceleration during sporting activities, such as landing from a jump, has been identified as a common mechanism of acute knee injury. Research into the role of potential sex differences in hip abductor function with lower extremity kinematics when landing from a jump is limited.Objective: To evaluate sex differences in hip abductor function ...

PubMed Central

159
[Voice disorder clinic in the speech therapy outpatient unit at "Hospital das Cl�nicas da Universidade Federal de Minas Gerais"].
2011-07-01

This study set out to describe the profile of the patients with voice complaints and/or alterations who were attended between July 2003 and December 2006 at the speech therapy outpatient unit of "Hospital das Cl�nicas da Universidade Federal de Minas Gerais." This was analyzed according to age, sex, profession, schooling, origin, treatment performed and factors that interfere in medical care ...

PubMed

160
[Prevalence of voice disorders among educational professionals. Factors contributing to their appearance or their persistence].
1998-03-01

A study was made of the prevalence of voice disorders and their risk factors in teaching professionals of Logro�o, Spain. A prevalence and case-control study was made, including interviews, ENT examination, videostrobolaryngoscopy, perceptual evaluation of hoarseness, basic aerodynamic tests, the physical range of phonation, and a physical analysis of the acoustic signal. The prevalence of voice ...

PubMed

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161
Trichotemnomania: obsessive-compulsive habit of cutting or shaving the hair.
2005-01-01

A 28-year-old woman presented with a completely hairless scalp. The disorder had started 1 year ago, and at the same time she had developed dysphonia. During the past year, her hair disease had been diagnosed as alopecia areata totalis by many specialists, including several dermatologists. A close inspection of her scalp, however, revealed that no alopecia was present, because ...

PubMed

162
Pharyngo-laryngeal discomfort after breast surgery: comparison between orotracheal intubation and laryngeal mask.
2008-05-02

Sore throat and dysphonia are a significant source of postoperative discomfort for patients scheduled for breast surgery who have been intubated for general anaesthesia. The aim of this study was to compare the incidence of postoperative pharyngo-laryngeal pain and dysphonia in the use of the laryngeal mask airway (LMA) or tracheal intubation in these ...

PubMed

163
Mediastinal goiter: a comprehensive study of 60 consecutive cases with special emphasis on identifying predictors of malignancy and sternotomy.
2011-09-01

BACKGROUND: We describe the clinical characteristics of patients with mediastinal goiter and our principles in surgical management of this pathology; we also identify the predictive factors of malignancy, sternotomy, and posterior mediastinal extension. METHODS: We conducted a retrospective chart review of 60 patients with mediastinal goiter who underwent surgical intervention. RESULTS: Major ...

PubMed

164
Inharmonicity Analysis: A Novel Physical Method for Acoustic Screening of Dysphonia
2008-10-01

In the United States 6.8% of men, women, and children report current voice problems and approximately 29% will report some problems during their lifetime. Often this dysphonia is due to pathologies of the vocal folds. The authors (a physicist and a speech pathologist) describe an interdisciplinary approach that shows promise of detecting physiological abnormalities of the ...

NASA Astrophysics Data System (ADS)

165
Unusual Cause of Right Ventricular Outflow Tract Compression: Mediastinal Lipomatosis.
2010-11-01

Mediastinal lipomatosis (ML) is a benign condition characterized by the accumulation of mature adipose tissue within the mediastinum. ML is usually associated with Cushing syndrome and obesity. Most patients are asymptomatic, but some have thoracic pain, dyspnea, cough, dysphonia, dysphagia, and supraventricular tachycardia. We report a case of ML compressing the right ...

PubMed

166
Thyrotoxicosis presenting as acute bulbar palsy.
2011-06-01

Myopathy chiefly affecting the proximal muscles of the limbs is frequently seen in hyperthyroidism. But isolated acute bulbar palsy without skeletal muscle involvement is rare in thyrotoxicosis. We report the case of a 52 year old man who presented with severe dysphagia, dysphonia and bouts of aspiration. Laboratory testing revealed an underlying Graves' thyrotoxicosis. His ...

PubMed

167
Rosai-Dorfman disease of the larynx.
2000-07-01

We present a case of an 81-year-old man with a history of worsening dysphonia of six months duration. A year before a sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) was diagnosed on a submandibular lymph node biopsy. On presentation the patient showed a mass in the left subglottic area with a modest reduction in the airway space. The patient underwent ...

PubMed

168
A rare differential diagnosis in dysphagia: wound botulism.
2006-05-01

The incidence of wound botulism is increasing dramatically among intravenous drug users. Efficient intensive care and early treatment with antitoxin is essential to avoid lethal courses. The clinical picture of botulism is of descending, symmetric, flaccid paralysis. Early symptoms include cranial nerve palsies resulting in blurred vision and diplopia, difficulty in focusing, ptosis, facial ...

PubMed

169
The Effect of Listener Experience and Anchors on Judgments of Dysphonia
2011-04-01

Purpose: To determine the effect of auditory anchors on judgments of overall severity (OS) and vocal effort (VE) in dysphonic speech when judgments are made by experienced and inexperienced listeners, and when self-rated by individuals with dysphonia (speaker-listeners). Method: Twenty individuals with dysphonia and 4 normal controls provided speech ...

ERIC Educational Resources Information Center

170
Subjective evaluation of the long-term efficacy of speech therapy on dysfunctional dysphonia.
2009-01-29

The objective of the study was to measure the subjective long-term effects of vocal therapy (more than 6 months) in 29 patients suffering from dysfunctional dysphonia. Four subjective measurements were used: one visual analog scale ranging from 0 (not efficient at all) to 100 (very efficient); one question "Is the speech therapy still efficient?," answered by yes or no; the ...

PubMed

171
Spectral moment analysis of unilateral vocal fold paralysis.
2010-09-02

Many acoustic measures have been used to assess and track the voices of patients with voice problems. Some of these measures rely on the accurate measurement of fundamental frequency to produce reliable results. Patients with voice disorders often produce voices with considerable quasiperiodicity or aperiodicity. There are other measurements that do not depend on the accurate tracking of ...

PubMed

172
Readability of Patient-Reported Outcome Questionnaires for Use With Persons With Dysphonia.
2011-05-18

OBJECTIVES: The purpose of this study was to examine the readability of several published patient-reported outcome (PRO) questionnaires for persons with dysphonia, and to compare the readability results with existing data about average reading levels for English-speaking adults living in the United States. DESIGN: A search was conducted to identify published PRO questionnaires ...

PubMed

173
Objective dysphonia quantification in vocal fold paralysis: comparing nonlinear with classical measures.
2009-11-08

Clinical acoustic voice-recording analysis is usually performed using classical perturbation measures, including jitter, shimmer, and noise-to-harmonic ratios (NHRs). However, restrictive mathematical limitations of these measures prevent analysis for severely dysphonic voices. Previous studies of alternative nonlinear random measures addressed wide varieties of vocal pathologies. Here, we analyze ...

PubMed

174
Objective Dysphonia Quantification in Vocal Fold Paralysis: Comparing Nonlinear with Classical Measures
2009-11-08

SummaryClinical acoustic voice-recording analysis is usually performed using classical perturbation measures, including jitter, shimmer, and noise-to-harmonic ratios (NHRs). However, restrictive mathematical limitations of these measures prevent analysis for severely dysphonic voices. Previous studies of alternative nonlinear random measures addressed wide varieties of vocal pathologies. Here, we ...

PubMed Central

175
Medialization thyroplasty: vocal outcome of silicone and titanium implant.
2010-07-09

Unilateral vocal fold paralysis can result in incomplete glottic closure, compromising the vocal efficiency and increasing the risk of aspiration. The glottic gap can be reduced by medialization thyroplasty. Both silicone and titanium implants have been described to be efficient in the improvement of the vocal outcome. The aim of this study was to assess the vocal outcome after medialization ...

PubMed

176
Using Homer To Teach the "Ramayana."
1994-04-01

An effective way to expand students' knowledge and enjoyment of noncanonical, or at least unfamiliar, works is by using more familiar works as benchmarks. For example, in a sophomore-level world literature survey course, students have already read a large part of the "Iliad" and all of the "Odyssey" when they are asked to study R. K. Narayan's shortened prose version of an Indian epic, the ...

ERIC Educational Resources Information Center

177
Timing of muscle activation in a hand movement sequence.
2006-05-12

Recent studies have described muscle synergies as overlapping, multimuscle groups defined by synchronous covariation in activation intensity. A different approach regards a synergy as a fixed temporal sequence of bursts of activity across groups of motoneurons. To pursue this latter definition, the present study used a principal component (PC) analysis tailored to reveal the across-muscle temporal ...

PubMed

178
The impact of adding trunk motion to the interpretation of the role of joint moments during normal walking.
2007-09-04

Biomechanical model assumptions affect the interpretation of the role of the muscle or joint moments to the segmental power estimated by induced acceleration analysis (IAA). We evaluated the effect of modeling the pelvis and trunk segments as two separate segments (8 SM) versus as a single segment (7 SM) on the segmental power, support of the body, knee and hip extension acceleration produced by ...

PubMed

179
The association between degenerative hip joint pathology and size of the gluteus maximus and tensor fascia lata muscles.
2009-01-03

The aim of this study was to obtain, using Magnetic Resonance Imaging (MRI), muscle volume measurements for the gluteus maximus (upper: UGM and lower: LGM portions) and tensor fascia lata (TFL) muscles in both healthy subjects (n=12) and those with unilateral osteoarthritis (OA) of the hip (mild: n=6, and advanced: n=6). While control group subjects were symmetrical between sides for the muscles ...

PubMed

180
Electromyographic correlates of learning during robotic surgical training in virtual reality.
2011-01-01

The purpose of this study was to investigate the muscle activation and the muscle frequency response of the dominant arm muscles (flexor carpi radialis and extensor digitorum) and hand muscles (abductor pollicis and first dorsal interosseous) during robotic surgical skills training in a virtual environment. The virtual surgical training tasks consisted of bimanual carrying, ...

PubMed

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181
Confounding factors in water EMG recordings: an approach to a definitive standard.
2006-03-22

This work presents a study on the influence of the aqueous environment on the surface EMG (sEMG) signal recorded in bipolar montage from the abductor pollicis brevis muscle, when only the forearm is immersed in water. Ten men, 30.1+/-4.0 (mean +/- SD) years old, performed ten 2-s 40% MVC isometric contractions of the abductor pollicis brevis muscle in two ...

PubMed

182
Biomechanics during exercise with a novel stairclimber.
2011-05-11

The current study aimed to investigate the stair-climbing biomechanics related to the lower extremities when subjects used the novel designed stair-climber, which could provide opportunity for both sagittal and frontal movements. 12 volunteers were required to step while either keeping the trunk static (STATIC) or allowing the trunk to shift with weight bearing (SHIFT). A motion analysis system ...

PubMed

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