This book is covered under the following headings: Structure Activity Relationships; Metabolism: P- 450; Metabolism; Testing Methods; Micronuclei; Aneuploidy; Chromosome Aberrations: General; Chromosome Aberrations: Mechanisms; and Chromosome Aberrations: Germinal.

... possibly due to spherical aberration within the ... same because of longitudinal chromatic aberration. ... Correcting chromatic aberrations using image ...

Fuzzy Spatiotemporal Data Mining to Activity Recognition in Smart Homes. Shared by Farzad amirjavid on Apr 28, 2011 ...

... Test for Chemical Induction of Chromosome Aberrations in Cultured Chinese Hamster Ovary (CHO) Cells With and Without Metabolic Activation ...

... Test for Chemical fuduction of Chromosome Aberrations in Cultured Chinese Hamster Ovary (CHO) Cells With and Without Metabolic Activation ...

... Test for Chemical Induction of Chromosome Aberrations in Cultured Chinese Hamster Ovary (CHO) Cells With and Without Metabolic Activation ...

... Title : Test for Chemical Induction of Chromosome Aberrations in Cultured Chinese Hamster (CHO) Cells With and Without Metabolic Activation ...

... Title : Test for Chemical Induction of Chromosome Aberrations in Cultured Chinese Hamster (CHO) Cells With and Without Metabolic Activation. ...

We demonstrate the use of a simple tool to simultaneously visualize and characterize chromatic and spherical aberrations that are present in multiphoton microscopy. Using two-dimensional Fourier transform spectral interferometry, we measured these aberrations, deducing in a single shot spatiotemporal effects in high-numerical-aperture ...

The optical performance of supersonic mixing layer is heavily deteriorated by the aero-optical aberration and dithering of coherent structures, but current measuring methods limit the spatiotemporal resolution in relevant studies. A high resolution whole-field aero-optical aberration and dithering measuring method based on the ...

We demonstrate a powerful and practical spectral interferometer with near-field scanning microscopy (NSOM) probes for measuring the spatiotemporal electric field of tightly focused ultrashort pulses with high spatial and spectral resolution. Our measurements involved numerical apertures as high as 0.44 and yielded the spatiotemporal field at and around the ...

Angiosperms display a wide variety of inflorescence architectures differing in the positions where flowers or branches arise. The expression of floral meristem identity (FMI) genes determines when and where flowers are formed. In Arabidopsis thaliana, this is regulated via transcription of LEAFY (LFY), which encodes a transcription factor that promotes FMI. We found that this is regulated in ...

Seizure activities often originate from a localized region of the cerebral cortex and spread across large areas of the brain. The properties of these spreading abnormal discharges may account for clinical phenotypes in epilepsy patients, although the manner of their propagation and the underlying mechanisms are not well understood. In the present study we performed ...

... the faculty of the Department of Electrical and Computer Engineering, in partial fulfillment of the requirements for the ... ...

The zinc finger transcription factor Gli3 is an essential mediator of hedgehog signaling. Gli3 has a dynamic expression pattern during embryonic development. In the neural tube, Gli3 transcripts are patterned along the anteroposterior and dorsoventral axes such that the initial broad expression in the posterior neural tube becomes dorsally restricted as neurogenesis takes place. Little is known ...

Cyclic adenosine 3',5'-monophosphate (cAMP) mediates the biological effects of various hormones and neurotransmitters. Stimulation of cardiac ?-adrenergic receptors (?-AR) via catecholamines leads to activation of adenylyl cyclases and increases cAMP production to enhance myocardial function. Because many other receptors signaling through cAMP generation exist in cardiac ...

SUMMARYNormal cellular development and function requires tight spatiotemporal control of actin assembly. Formins are potent actin assembly factors that protect the growing ends of filaments from capping proteins. However, it is unresolved how the duration of formin-mediated actin assembly events is controlled, whether formins are actively displaced from ...

An array of SQUID biomagentometers may be used to measure the spatio-temporal neuromagnetic field produced by the brain in response to a given sensory stimulus. A popular model for the neural activity that produces these fields is a set of current dipoles...

The goal of this study was to evaluate the effect of ophthalmic lens-induced transverse chromatic aberrations (TCA) in natural viewing conditions on spatio-temporal thresholds. Three psychophysical experiments were performed; the first isolating the spatial component, the second isolating the temporal component and the third assessing ...

Dec 24, 2003 ... All of this takes place in the here and now of neuron firing and axon bundles of a present time and constitute a kind of active blackboard ...

Mellon, 2005. [18] M. Tambe. Tracking dynamic team activity. In Proc. AAAI, 1996. [19] G. Zu and Z. ZhangRobust Recognition of Physical Team Behaviors Using Spatio-Temporal Models Gita Sukthankar Robotics presents a framework for robustly recognizing physical team behaviors by exploiting spatio-temporal pat

... Chromosome aberrations were scored from the cells treated with the concentrations of 500, 1000 and 5000 g/ml, without or with activation. ...

Spherical aberrations of the thermal lens of the active media are severe when solid state lasers are strongly pumped. The fundamental mode profile deteriorates due to the aberrations. Self-consistent modes of a resonator with aberrations are calculated by using the Fox-Li diffraction iterative algorithm. ...

In this paper we address the problem of localization and recognition of human activities in unsegmented image sequences. The main contribution of the proposed method is the use of an implicit representation of the spatiotemporal shape of the activity which relies on the spatiotemporal localization of characteristic ...

With the rapid development of geographic information system (GIS), computer aided design (CAD), mobile computing and multimedia databases, spatiotemporal databases have been the focus of considerable research activities over a significant period. It becomes an enabling technology for important applications such as land use, real estate, transportation, ...

The relationship between activity of chromosomal nucleolus-organizer regions and levels of chromosome aberrations was studied in 215 residents of the Kursk region by visual semiquantitative method (silver staining of the nucleolus-organizer regions, NOR) in chromosomes of peripheral blood lymphocytes. The levels of chromosome ...

Many of the collective activities performed by social insects result in the formation of complex spatio-temporal patterns. Without...

... formulas for long-term and short-term memory models characterizing the neurotransmitter and cell-activity levels of a synapse and neuron. ...

Dec 24, 2003 ... Some of Calvin's examples involve spatio-temporal patterns that do not rely on a cloning competition or the activation of a entire structure ...

C. Robin Mattheus, Hamilton College Summary The activity is designed to help students conceptualize the spatiotemporal relationships between erosion and deposition across a convex topography, which serves as a ...

EDI - Electron Drift Instrument ASPOC- Active Spacecraft Potential Control experiment. STAFF - Spatio-Temporal Analysis of Field Fluctuation experiment ...

Jan 22, 2011 ... Jun-2004, Argumentation for coordinating shared activities, Clement, ... Jun- 2004, Accessing and visualizing scientific spatiotemporal data ...

... PN neural processor generates a variety of transient and steady-state activities that may be used for spatiotemporal filtering (STF), motion detection ...

The data set reproduced well-documented spatio-temporal trends and inter-annual variations in vegetation activity in the northern latitudes and semi-arid ...

It is established that sodium trichloracetate does not induce chromosomal aberrations in bone marrow cells of mice, does not modify mutagenic effect induced by rubomicin, but increases chromosome aberration frequency in the culture of human peripheral lymphocytes and in germs of Crepis tectorum and Allium cepa seeds. PMID:6474569

Aberrant Retinal Projections in Congenitally Deaf Mice: How Are Phenotypic Characteristics of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, College of Medicine deaf, the developing nervous system has no exposure to sensory-driven neural activity from the auditory

The results of chromosome aberration analyses in 68 Thorotrast patients are discussed. In all patients dicentric chromosome aberrations were found but the chromosome aberration rate neither corresponds with the calculated whole body activity or the estimated absorbed dose in the organs of the RHS nor with the ...

There is ample evidence that parietal cortices serve as key components of the mechanism responsible for number processing. The goal of the present study was to investigate the relative degree and timing of cortical activation in parietal, temporal, and frontal regions during simple arithmetic tasks in children who experience math difficulties. Real-time brain ...

Visual semiquantitative method of silver staining of nucleolus organizer regions in peripheral blood leukocytes was applied for evaluation of the correlation between activity of nucleolus organizer regions and the level of chromosome aberrations in 241 residents of Kursk region. Significant differences in the percent of chromosome ...

The topics discussed include relationship between cell cycle and the incidence of chromosome aberration; various types of aberration; lymphocyte culture; relation of cultured lymphocyte with radiation-induced chromosome aberration, especially with radiation dosage. The types of chromosome aberration vary ...

The dynamic correction of aberrations introduced in optical systems have been a widely discussed topic in the past 10 years. Adaptive optics is the most important developed field where the Shack-Hartmann sensors and deformable mirrors are used for the measurement and correction of wavefronts. In this paper, an interferometric set-up which uses a Spatial Light Modulator (SLM) ...

Spatiotemporal self-organization is found in a wide range of distributed dynamical systems. The coupling of the active elements in these systems may be local or global or within a network, and the interactions may be diffusive or nondiffusive in nature. The articles in this focus issue describe biological and chemical systems designed to exhibit ...

The spatiotemporal structure of brain oscillations are important in understanding neural function. We analyze oscillatory episodes from isotropic preparations from the middle layers of a mammalian cortex which display irregular and chaotic spatiotemporal wave activity, within which spontaneously emerge spiral and plane waves. The ...

Magnolia bark extract (MBE) has been used historically in traditional Chinese and Japanese medicines, and more recently as a component of dietary supplements and cosmetic products. The genotoxic potential of MBE was studied in two in vitro chromosomal aberration assays. In Chinese hamster ovary (CHO) cells, exposure for 3 h to MBE at concentrations of 0-30 microg/ml in the ...

We present experimental and theoretical results on aberration control in solid state laser amplifiers and resonators. In lasers with diffraction-limited beam quality, aberrations cause diffraction losses that reduce the output power. In laser amplifiers, aberrations in the active medium degrade the beam quality of ...

In this paper we report the use of adaptive optics to correct for sample induced aberrations in optical microscopy, crucially comparing individual pixel-by-pixel correction against a single correction for an entire optical section. Sample induced optical aberrations in slices of rat brain tissue were corrected with a deformable membrane mirror. Using axial ...

Neuroscientists have uncovered much about the dorsal and ventral visual object processing pathways. However, little is understood about the functional development of these pathways in human infants. Behavioral data has shown that as early as 2.5 months, infants are sensitive to spatiotemporal information for object individuation in occlusion events. This study used Near ...

We used optical imaging of voltage-sensitive dye signals to study the spatiotemporal spread of activity in the mouse barrel cortex, evoked by stimulation of thalamocortical afferents in an in vitro slice preparation. Stimulation of the thalamus, at low current intensity, results in activity largely restricted to a single barrel, and to ...

Implantation is a complex event requiring synchronization between a developing embryo and receptive endometrium. This process is governed by molecular mechanism mediated by homeobox (Hox) genes, which encode transcription factors. These factors guide embryologic development as well as regulate differential gene expression within the endometrium with each menstrual cycle. ...

A generic 3D laser-pulse-shaping scheme is proposed towards the generation of a uniform ellipsoidal particle distribution, an ideal distribution due to the linear dependence of the space-charge force on the particle position. The shaping is accomplished via spatiotemporal coupling of the laser dynamics via chromatic aberration in an optical lens. Particle ...

A generic 3D laser-pulse-shaping scheme is proposed towards the generation of a uniform ellipsoidal particle distribution, an ideal distribution due to the linear dependence of the space-charge force on the particle position. The shaping is accomplished via spatiotemporal coupling of the laser dynamics via chromatic aberration in an optical lens. Particle ...

Noninvasive activation time (AT) imaging using electrocardiographic (ECG) mapping data provides information about electrical propagation through the heart with a high spatio-temporal resolution. This study presents an attempt to clinically validate AT ima...

The execution of the mitotic program with high fidelity is dependent upon precise spatiotemporal regulation of posttranslational protein modifications. For example, the timely polyubiquitination of critical mitotic regulators by Anaphase Promoting Complex/Cyclosome (APC/C) is essential for the metaphase to anaphase transition and mitotic exit. The spindle assembly checkpoint ...

Previous studies of face processing in autism suggest abnormalities in anatomical development, functioning and connectivity/coordination of distributed brain systems involved in social cognition, but the spatial sequence and time course of rapid (sub-second) neural responses to emotional facial expressions have not been examined in detail. Source analysis of high-density event-related potentials ...

BackgroundMouse genetic study has demonstrated that Axin2 is essential for calvarial development and disease. Haploid deficiency of ?-catenin alleviates the calvarial phenotype caused by Axin2 deficiency. This loss-of-function study provides evidence for the requirement of ?-catenin in exerting the downstream effects of Axin2.ResultsHere we utilize a gain-of-function analysis to further assess the ...