Sample records for abertos emma goldman

  1. The Life and Times of Emma Goldman: A Curriculum for Middle and High School Students.

    ERIC Educational Resources Information Center

    Falk, Candace; Reese, Lyn; Dougherty, Mary Agnes

    Emma Goldman (1869-1940) is a major figure in the history of radicalism and feminism in the United States. In a period when the expression of controversial ideas was dangerous, Goldman insisted on her right to challenge convention. She was among the most prominent advocates of labor's right to organize, reproductive rights, sexual freedom, freedom…

  2. "I am a trained nurse": the nursing identity of anarchist and radical Emma Goldman.

    PubMed

    Connolly, Cynthia Anne

    2010-01-01

    For more than a century, scholars have analyzed the many dimensions of Emma Goldman. Remembered as an agent of revolution, feminism, sexual freedom, anarchy, and atheism, Goldman's motives, personality, and actions have generated an entire subgenre of historical scholarship. But although Goldman practiced nursing in New York City for ten years, one facet of her life that has been neglected is her nursing identity. Goldman's autobiography, Living My Life, reveals the way her nursing experiences informed her evolving anarchist political philosophy and international activism. She valued nursing for many reasons--for the economic independence it offered, identity it provided, and sense of community and connectivity she believed it encouraged. Finally, for Goldman, nursing represented was a vehicle to understand people's struggles and as a way of translating political philosophy into meaningful, practical solutions.

  3. With Speech as My Weapon: Emma Goldman and the First Amendment. A Unit of Study for Grades 8-12.

    ERIC Educational Resources Information Center

    Falk, Candace; Cole, Stephen; Thomas, Sally

    This supplementary teaching unit provides students with the opportunity to explore freedom of expression by focusing on Emma Goldman (1869-1940), a major figure in the history of American radicalism and feminism. In a period when the expression of controversial ideas was dangerous, Goldman insisted on her right to challenge conventions. She…

  4. Radical Lessons: Thoughts on Emma Goldman, Chaos, Grief, and Political Violence Post-9/11/01

    ERIC Educational Resources Information Center

    Kensinger, Loretta

    2009-01-01

    Since that fateful day in September 2001, and in its terrible aftermath, the author has often sought inspiration from a wider community of humans seeking to create a different, less terrifying, world. In concluding her 1912 article, "The New Year," Emma Goldman boldly asserted, "Out of the chaos the future emerges in harmony and beauty." Chaos is…

  5. The Life and Times of Emma Goldman: A Curriculum for Middle and High School Students. Primary Historical Documents on: Immigration, Freedom of Expression, Women's Rights, Anti-Militarism, Art and Literature of Social Change.

    ERIC Educational Resources Information Center

    Falk, Candace; And Others

    The documents in this curriculum unit are drawn from the massive archive collected by the Emma Goldman Papers Project at the University of California (Berkeley). They are linked to the standard social studies and humanities curriculum themes of art and literature, First Amendment rights, labor, progressive politics, and Red Scare, the rise of…

  6. Goldman visits Washington, D.C.

    NASA Image and Video Library

    2009-03-24

    Stennis Space Center Director Gene Goldman (right) visited Washington, D.C,. last month, where he called on Louisiana and Mississippi leaders to update them on work at the rocket engine testing facility. Rep. Gene Taylor, D-Miss., was among those visited by Goldman on March 24.

  7. EMMA: Towards Multicultural Learning

    ERIC Educational Resources Information Center

    Kerr, Ruth; Merciai, Ilaria

    2016-01-01

    Interest on the part of European Institutions to explore the potential of MOOCs for providing the kind of inclusive and multicultural education that was needed for 21st century learners was confirmed by funding of projects such as EMMA (http://www.europeanmoocs.eu). The definition of "European" for the EMMA consortium was based on…

  8. EMMA: The expert system for munition maintenance

    NASA Technical Reports Server (NTRS)

    Mullins, Barry E.

    1988-01-01

    Expert Missile Maintenance Aid (EMMA) is a first attempt to enhance maintenance of the tactical munition at the field and depot level by using artificial intelligence (AI) techniques. The ultimate goal of EMMA is to help a novice maintenance technician isolate and diagnose electronic, electromechanical, and mechanical equipment faults to the board/chassis level more quickly and consistently than the best human expert using the best currently available automatic test equipment (ATE). To this end, EMMA augments existing ATE with an expert system that captures the knowledge of design and maintenance experts. The EMMA program is described, including the evaluation of field-level expert system prototypes, the description of several study tasks performed during EMMA, and future plans for a follow-on program. This paper will briefly address several study tasks performed during EMMA. The paper concludes with a discussion of future plans for a follow-on program and other areas of concern.

  9. Reading embodied consciousness in "Emma".

    PubMed

    Harbus, Antonina

    2011-01-01

    The language of Emma (1815) reflects Jane Austen's developing view of embodied consciousness and her particular interest in this novel in the physical manifestations of emotions, such as blushes and nervous responses. The discursive exploration of the inner life in Emma is the product of a cultural context that features emerging brain science and Austen's own conceptualization of the psychophysical nature of emotions. This article analyzes the language of mind and emotion in Emma, to contend that Austen grapples with the implications of the idea of embodied consciousness in a narrative that contrasts mind reading with interpreting the body.

  10. Would they dope? Revisiting the Goldman dilemma.

    PubMed

    Connor, James; Woolf, Jules; Mazanov, Jason

    2013-07-01

    Discussions of doping often report Goldman's sensational results that half of the elite athletes asked would take a drug that guaranteed sporting success which would also result in their death in 5 years' time. There has never been any effort to assess the properties of the 'Goldman dilemma' or replicate the results in the post World Anti-Doping Agency context. This research evaluated the dilemma with contemporary elite athletes. Participants at an elite-level track and field meet in North America were segregated into an interview or online response. After basic demographics, participants were presented with three variant 'Goldman' dilemmas counter-balanced for presentation order. Only 2 out of 212 samples  (119 men, 93 women, mean age 20.89) reported that they would take the Faustian bargain offered by the original Goldman dilemma. However, if there were no consequences to the (illegal) drug use, then 25/212 indicated that they would take the substance (no death condition). Legality also changes the acceptance rate to 13/212 even with death as a consequence. Regression modelling showed that no other variable was significant (gender, competitive level, type of sport) and there was no statistical difference between the interview and online collection method. Goldman's results do not match our sample. A subset of athletes is willing to dope and another subset is willing to sacrifice their life to achieve success, although to a much lesser degree than that observed by Goldman. A larger scale online survey is now viable to answer important questions such as variation across sports.

  11. Goldman - Georgetown University | Division of Cancer Prevention

    Cancer.gov

    Principal Investigator: Radoslav (Rado) Goldman, PhDInstitution: Georgetown University, Washington, DC Subcontract Principal Investigator: Raja Mazumder, PhDInstitution: George Washington University |

  12. 75 FR 44031 - Goldman, Sachs & Co., et al.; Notice of Application and Temporary Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... International (``GSAMI''), Goldman Sachs Hedge Fund Strategies LLC (``GSHFS''), Commonwealth Annuity and Life... marketing materials used in connection with residential mortgage-related securities offerings by Goldman... marketing materials, (iv) where Goldman Sachs is the lead underwriter of an offering of residential mortgage...

  13. Can EMMA solve the puzzle of the knee?

    NASA Astrophysics Data System (ADS)

    Kalliokoski, T.; Bezrukov, L.; Enqvist, T.; Fynbo, H.; Inzhechik, L.; Jones, P.; Joutsenvaara, J.; Karjalainen, J.; Kuusiniemi, P.; Loo, K.; Lubsandorzhiev, B.; Petkov, V.; Räihä, T.; Sarkamo, J.; Slupecki, M.; Trzaska, W. H.; Virkajärvi, A.

    2011-04-01

    The knee is a change in the slope of the cosmic ray spectrum at approximate energy of 3 PeV. There are multiple competing models for the knee giving conflicting predictions about this change for different masses of the primary particle. Accurate mass measurements of cosmic rays spectra around 3 PeV would be able to exclude some of these models. Cosmic-ray experiment EMMA uses a new method for studying the composition of cosmic rays at the knee area. It is able to determine the multiplicity, the lateral distribution, and the arrival direction of incoming muons produced early in the shower evolution on an event-by-event basis and deduce from these measurements the mass and the energy of the primary particle. EMMA is situated at the depth of 75 m in the Pyhäsalmi mine, Finland. This rock overburden, which corresponds to 210 m of water equivalent, gives EMMA a cut-off energy of 50 GeV for vertical muons. Since the simulations using different air-shower models give similar predictions for the lateral distribution of these high energy muons, we are confident that EMMA should yield a reliable and an air-shower model independent data on the composition of cosmic rays around the knee region.

  14. EMMA: a new paradigm in configurable software

    DOE PAGES

    Nogiec, J. M.; Trombly-Freytag, K.

    2017-11-23

    EMMA is a framework designed to create a family of configurable software systems, with emphasis on extensibility and flexibility. It is based on a loosely coupled, event driven architecture. The EMMA framework has been built upon the premise of composing software systems from independent components. It opens up opportunities for reuse of components and their functionality and composing them together in many different ways. As a result, it provides the developer of test and measurement applications with a lightweight alternative to microservices, while sharing their various advantages, including composability, loose coupling, encapsulation, and reuse.

  15. EMMA: A New Paradigm in Configurable Software

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nogiec, J. M.; Trombly-Freytag, K.

    EMMA is a framework designed to create a family of configurable software systems, with emphasis on extensibility and flexibility. It is based on a loosely coupled, event driven architecture. The EMMA framework has been built upon the premise of composing software systems from independent components. It opens up opportunities for reuse of components and their functionality and composing them together in many different ways. It provides the developer of test and measurement applications with a lightweight alternative to microservices, while sharing their various advantages, including composability, loose coupling, encapsulation, and reuse.

  16. EMMA: a new paradigm in configurable software

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nogiec, J. M.; Trombly-Freytag, K.

    EMMA is a framework designed to create a family of configurable software systems, with emphasis on extensibility and flexibility. It is based on a loosely coupled, event driven architecture. The EMMA framework has been built upon the premise of composing software systems from independent components. It opens up opportunities for reuse of components and their functionality and composing them together in many different ways. As a result, it provides the developer of test and measurement applications with a lightweight alternative to microservices, while sharing their various advantages, including composability, loose coupling, encapsulation, and reuse.

  17. EMMA: a new paradigm in configurable software

    NASA Astrophysics Data System (ADS)

    Nogiec, J. M.; Trombly-Freytag, K.

    2017-10-01

    EMMA is a framework designed to create a family of configurable software systems, with emphasis on extensibility and flexibility. It is based on a loosely coupled, event driven architecture. The EMMA framework has been built upon the premise of composing software systems from independent components. It opens up opportunities for reuse of components and their functionality and composing them together in many different ways. It provides the developer of test and measurement applications with a lightweight alternative to microservices, while sharing their various advantages, including composability, loose coupling, encapsulation, and reuse.

  18. A different voice: Mary Hays's the Memoirs of Emma Courtney.

    PubMed

    Sharma, A

    2001-01-01

    Mary Hays wrote in the decade of the 1790s, a period of intense creative flowering in England. Writing in a period enshrined to the works of the canonical Wordsworth and Coleridge, Hays explored through her Jacobinical novel, The Memoirs of Emma Courtney, the contentious relationship between self and society. Like other Jacobin women writers - Elizabeth Inchbald, Charlotte Smith and Mary Wollstonecraft - Mary Hays too used her novel to explode the insidious connection between education and gender construction. Emma Courtney is a landmark novel that wrestles with the paradigm of decorum and propriety which disallows women from voicing their aspirations. In the process, Hays merges the plots of the domestic novel of courtship and love with the novel of ideas to create a searing portrait of women's intellectual confinement and psychic dissonance in a society that only projects them in terms of their gender construction. Memoirs of Emma Courtney is a remarkable novel in its depiction of the emotional imbalance created by thwarted desire: intellectual and sexual.

  19. Teaching the 'A' Level Text: Emma.

    ERIC Educational Resources Information Center

    Huband, David

    1987-01-01

    Notes how important it is that any critical writing assignments should take into account the individual reading, and that the teacher's role is to steer discussion that stems from a class of individual readings. Explores some of the aspects of Jane Austen's novel "Emma" to which students readily respond. (HTH)

  20. Trading Health Risks for Glory: A Reformulation of the Goldman Dilemma.

    PubMed

    González, Juan Marcos; Johnson, F Reed; Fedoruk, Matthew; Posner, Joshua; Bowers, Larry

    2018-03-01

    The Goldman dilemma presented athletes with a Faustian bargain that guaranteed winning an Olympic gold medal in their sport but resulted in certain death 5 years later. Athletes' responses to Goldman's bargain were reported from 1982 to 1995. Several studies subsequently evaluated people's willingness to accept the bargain proposed in the Goldman question. Our study updates Goldman's question using contingent-behavior questions, a preference-elicitation method widely applied in economics, marketing and psychology to understand people's choice behavior. Contingent-behavior questions ask people to evaluate hypothetical tradeoffs between outcomes when real-world decisions are unobservable, nonexistent, or unreliable. A web-enabled survey was conducted with athletes in 50 sports between June, 2012 and April, 2013. Athletes were invited by their sport governing bodies in the United States to complete the online survey. Responses from 2888 athletes were collected. Our reformulation elicited athletes' willingness to accept a performance-enhancing drug (PED) associated with the risk of a realistic fatal event, not certain death. A double-bounded dichotomous-choice question format was used to elicit athletes' maximum acceptable mortality risk (MAMR) for winning an Olympic gold medal. Data were analyzed using an interval regression model to estimate the implicit probability of accepting a continuous risk level. MAMR was defined as the mortality risk level with a 0.50 probability of acceptance. Estimated mean MAMRs varied between 7 and 14% across athletes in different ranks and sports. Elite athletes were generally the most willing to accept a fatal cardiovascular risk to win a gold medal in the Olympics. This range was similar to the levels of risk that patients accept for life-changing interventions. Results suggest that very few athletes would be expected to accept a PED in the bargain postulated by the Goldman dilemma. Risk tolerance among elite athletes suggest they may

  1. Withstanding trauma: the significance of Emma Eckstein's circumcision to Freud's Irma dream.

    PubMed

    Bonomi, Carlo

    2013-07-01

    The author considers the medical rationale for Wilhelm Fliess's operation on Emma Eckstein's nose in February 1895 and interprets the possible role that this played in Freud's dream of Irma's injection five months later. The author's main argument is that Emma likely endured female castration as a child and that she therefore experienced the surgery to her nose in 1895 as a retraumatization of her childhood trauma. The author further argues that Freud's unconscious identification with Emma, which broke through in his dream of Irma's injection with resistances and apotropaic defenses, served to accentuate his own "masculine protest". The understanding brought to light by the present interpretation of Freud's Irma dream, when coupled with our previous knowledge of Freud, allows us to better grasp the unconscious logic and origins of psychoanalysis itself.(1.) © 2013 The Psychoanalytic Quarterly, Inc.

  2. Social and Population Structure in the Ant Cataglyphis emmae

    PubMed Central

    Jowers, Michael J.; Leniaud, Laurianne; Cerdá, Xim; Alasaad, Samer; Caut, Stephane; Amor, Fernando; Aron, Serge; Boulay, Raphaël R.

    2013-01-01

    Dispersal has consequences not only for individual fitness, but also for population dynamics, population genetics and species distribution. Social Hymenoptera show two contrasting colony reproductive strategies, dependent and independent colony foundation modes, and these are often associated to the population structures derived from inter and intra-population gene flow processes conditioned by alternative dispersal strategies. Here we employ microsatellite and mitochondrial markers to investigate the population and social genetic structure and dispersal patterns in the ant Cataglyphis emmae at both, local and regional scales. We find that C. emmae is monogynous and polyandrous. Lack of detection of any population viscosity and population structure with nuclear markers at the local scale suggests efficient dispersal, in agreement with a lack of inbreeding. Contrasting demographic differences before and during the mating seasons suggest that C. emmae workers raise sexuals in peripheric nest chambers to reduce intracolonial conflicts. The high genetic differentiation recovered from the mtDNA haplotypes, together with the significant correlation of such to geographic distance, and presence of new nuclear alleles between areas (valleys) suggest long-term historical isolation between these regions, indicative of limited dispersal at the regional scale. Our findings on the ecological, social and population structure of this species increases our understanding of the patterns and processes involved under independent colony foundation. PMID:24039827

  3. Bem vindo - Portal Brasileiro de Dados Abertos

    Science.gov Websites

    Pular para o conteúdo Portal do Governo Brasileiro Ir para o conteúdo 1 Ir para o menu 2 Ir para a busca 3 Ir para o rodapé 4 dados.gov.br Portal Brasileiro de Dados Abertos Enviar feed twitter CÃ

  4. TPF-I Emma X-Array: 2007 Design Team Study

    NASA Technical Reports Server (NTRS)

    Martin, Stefan R.; Rodriguez, Jose; Scharf, Dan; Smith, Jim; McKinstry, David; Wirz, Richie; Purcell, George; Wayne, Len; Scherr, Larry; Mennesson, Bertrand; hide

    2007-01-01

    This viewgraph presentation is a study of an Emma design for Terrestrial Planet Finder (TPF) formation flying interferometer. The objective is to develop a design with reduced cost compared to TPF-I X-Array, derive mass and cost estimates, and study thermal and radiation issues.

  5. Oh No, Not the "A" Word! Proposing an "Anarchism" for Education

    ERIC Educational Resources Information Center

    DeLeon, Abraham

    2008-01-01

    Anarchist theory has a long-standing history in political theory, sociology, and philosophy. As a radical discourse, anarchist theory pushes educators and researchers towards new conceptualizations of community, theory, and praxis. Early writers, like Joseph Proudhoun and Emma Goldman, to more contemporary anarchists, such as Noam Chomsky, have…

  6. Molecular cloning, characterization, and expression analysis of an ecdysone receptor homolog in Teleogryllus emma (Orthoptera: Gryllidae).

    PubMed

    He, Hui; Xi, Gengsi; Lu, Xiao

    2015-01-01

    Ecdysteroids are steroid hormones that play important roles in the regulation of Arthropoda animal growth development, larvae ecdysis, and reproduction. The effect of ecdysteroids is mediated by ecdysteroid receptor (EcR). The ecdysone receptor (EcR) belongs to the superfamily of nuclear receptors (NRs) that are ligand-dependent transcription factors. Ecdysone receptor is present only in invertebrates and plays a critical role in regulating the expression of a series of genes during development and reproduction. Here, we isolated and characterized cDNA of the cricket Teleopgryllus emma (Ohmachi & Matsuura) (Orthoptera: Gryllidae) and studied mRNA expression pattern using real time-polymerase chain reaction. The full-length cDNA of T. emma EcR, termed TeEcR, is 2,558 bp and contains a 5'-untranslated region of 555 bp and a 3'-untranslated region of 407 bp. The open reading frame of TeEcR encodes deduced 531-amino acid peptides with a predicted molecular mass of 60.7 kDa. The amino acid sequence of T. emma EcR was similar to that of known EcR especially in the ligand-binding domain of insect EcR. Real-time quantitative reverse transcription-polymerase chain reaction was performed to compare TeEcR mRNA expression level at the whole body and gonad during T. emma development. The data revealed that TeEcR mRNA is differentially expressed during T. emma development, with the highest expression level in late-instar larvae of the body and lowest in third instar. The levels of TeEcR transcripts also vary among gonads development, and levels in ovaries were higher than in testes at every developmental stage. These results suggest that TeEcR may have potential significance to regulate the morphological structure and gonad development of T. emma, due to its expression in different developmental periods. © The Author 2015. Published by Oxford University Press on behalf of the Entomological Society of America.

  7. Molecular Cloning, Characterization, and Expression Analysis of an Ecdysone Receptor Homolog in Teleogryllus emma (Orthoptera: Gryllidae)

    PubMed Central

    He, Hui; Xi, Gengsi; Lu, Xiao

    2015-01-01

    Ecdysteroids are steroid hormones that play important roles in the regulation of Arthropoda animal growth development, larvae ecdysis, and reproduction. The effect of ecdysteroids is mediated by ecdysteroid receptor (EcR). The ecdysone receptor (EcR) belongs to the superfamily of nuclear receptors (NRs) that are ligand-dependent transcription factors. Ecdysone receptor is present only in invertebrates and plays a critical role in regulating the expression of a series of genes during development and reproduction. Here, we isolated and characterized cDNA of the cricket Teleopgryllus emma (Ohmachi & Matsuura) (Orthoptera: Gryllidae) and studied mRNA expression pattern using real time-polymerase chain reaction. The full-length cDNA of T. emma EcR, termed TeEcR, is 2,558 bp and contains a 5′-untranslated region of 555 bp and a 3′-untranslated region of 407 bp. The open reading frame of TeEcR encodes deduced 531-amino acid peptides with a predicted molecular mass of 60.7 kDa. The amino acid sequence of T. emma EcR was similar to that of known EcR especially in the ligand-binding domain of insect EcR. Real-time quantitative reverse transcription-polymerase chain reaction was performed to compare TeEcR mRNA expression level at the whole body and gonad during T. emma development. The data revealed that TeEcR mRNA is differentially expressed during T. emma development, with the highest expression level in late-instar larvae of the body and lowest in third instar. The levels of TeEcR transcripts also vary among gonads development, and levels in ovaries were higher than in testes at every developmental stage. These results suggest that TeEcR may have potential significance to regulate the morphological structure and gonad development of T. emma, due to its expression in different developmental periods. PMID:25797799

  8. Bravo Emma! Music in the life and work of Charles Darwin.

    PubMed

    Derry, J F

    2009-03-01

    The long-term marital dance of Emma and Charles Darwin was set to the routine beat of an almost daily piano recital. Emma was a proficient pianist, and so a quality instrument was a welcome and appropriate house-warming present for their first marital home in London. That same piano accompanied the Darwins on their move to Downe before being upgraded for a newer model, which is still there, whilst another, cheaper piano may have played in Charles Darwin's work, particularly on earthworms. Whilst he lamented his own lack of musicality, Darwin revelled in his wife's prowess, a capacity that he recognised could be inherited, not least through observation of his own children. The evolution of musicality, he reasoned, was rooted in sexual attraction as a form of communication that preceded language.

  9. Progressive-Era Resources on the World Wide Web.

    ERIC Educational Resources Information Center

    Howenstein, Amanda

    1999-01-01

    Provides a list of Progressive-era websites with the address and a detailed description of each of the websites. Includes topics such as the womens suffrage movement, the Triangle Shirtwaist Factory fire, the Prohibition, labor-management conflicts, the Hull House, the Chicago fire, Emma Goldman, Progressive-era entertainment, and the Worlds Fair.…

  10. 78 FR 24447 - Goldman Sachs Trust, et al.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 30471; 812-14075] Goldman Sachs Trust, et al.; Notice of Application April 19, 2013. AGENCY: Securities and Exchange Commission..., or cause more than 10% of the acquired company's voting stock to be owned by investment companies and...

  11. 78 FR 26407 - Goldman Sachs Trust II, et al.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ... Sachs Trust II, et al.; Notice of Application April 29, 2013. AGENCY: Securities and Exchange Commission... would grant relief from certain disclosure requirements. APPLICANTS: Goldman Sachs Trust II (the ``Trust...'', each of GSAM and GSAMI an ``Adviser'' and collectively, ``Advisers,'' and together with the Trust...

  12. An Adaptive Display to Treat Stress-Related Disorders: EMMA's World

    ERIC Educational Resources Information Center

    Banos, R. M.; Botella, C.; Guillen, V.; Garcia-Palacios, A.; Quero, S.; Breton-Lopez, J.; Alcaniz, M.

    2009-01-01

    Most of the virtual environments currently available in the field of psychological treatments were designed to solve a specific problem. Our research group has developed a versatile virtual reality system (an adaptive display) called "EMMA's world", which can address a wide range of problems. It was designed to assist in clinical situations where…

  13. Bringing Child Psychology to Religious Curricula: The Cautionary Tale of Goldman and Piaget.

    ERIC Educational Resources Information Center

    Kay, William K.

    1996-01-01

    British researcher Ronald Goldman's attempts to apply Piagetian theory to children's interpretation of biblical narratives illustrates that the theory is ill suited to text interpretation. However, there are ways that child psychology can contribute to religious education. (SK)

  14. iPhone, Android, or Kindle: The Emma S. Clark Memorial Library Has an App for That and So Can You

    ERIC Educational Resources Information Center

    Johnson, Bob; Gutmann, Ted

    2013-01-01

    If you are like the millions of people buying the latest smartphone, iPhone 5, or Samsung Galaxy S III, your local library should have something to offer you. The Emma S. Clark Memorial Library, for one, has an app for that! Dubbed "Emma Mobile," the library's application works with iOS (Apple), Android (Google), and Amazon Kindle Fire…

  15. Revised age of deglaciation of Lake Emma based on new radiocarbon and macrofossil analyses

    USGS Publications Warehouse

    Elias, S.A.; Carrara, P.E.; Toolin, L.J.; Jull, A.J.T.

    1991-01-01

    Previous radiocarbon ages of detrital moss fragments in basal organic sediments of Lake Emma indicated that extensive deglaciation of the San Juan Mountains occurred prior to 14,900 yr B.P. (Carrara et al., 1984). Paleoecological analyses of insect and plant macrofossils from these basal sediments cast doubt on the reliability of the radiocarbon ages. Subsequent accelerator radiocarbon dates of insect fossils and wood fragments indicate an early Holocene age, rather than a late Pleistocene age, for the basal sediments of Lake Emma. These new radiocarbon ages suggest that by at least 10,000 yr B.P. deglaciation of the San Juan Mountains was complete. The insect and plant macrofossils from the basal organic sediments indicate a higher-than-present treeline during the early Holocene. The insect assemblages consisted of about 30% bark beetles, which contrasts markedly with the composition of insects from modern lake sediments and modern specimens collected in the Lake Emma cirque, in which bark beetles comprise only about 3% of the assemblages. In addition, in the fossil assemblages there were a number of flightless insect species (not subject to upslope transport by wind) indicative of coniferous forest environments. These insects were likewise absent in the modern assemblage. ?? 1991.

  16. Molecular Cloning, Characterization, and Expression Analysis of an Estrogen Receptor-Related Receptor Homologue in the Cricket, Teleogryllus emma

    PubMed Central

    He, Hui; Xi, Gengsi; Lu, Xiao

    2010-01-01

    The estrogen receptor-related receptors (ERRs) are a group of nuclear receptors that were originally identified on the basis of sequence similarity to estrogen receptors. The three mammalian ERR genes have been implicated in diverse physiological processes ranging from placental development to maintenance of bone density, but the function and regulation of ERRs in invertebrates are not well understood. A homologue of human ERR was isolated from the cricket Teleogryllus emma (Ohmachi and Matsumura) (Orthoptera: Gryllidae). The full-length cDNA of T. emma ERR, termed TeERR, has 1618 base pair (bp) and contains a 5′?-untranslated region of 140 bp and a 3′?-untranslated region of 272 bp. The open reading frame of TeERR encodes a deduced 401 amino acid peptide with a predicted molecular mass of 45.75 kilodaltons. The results of sequence alignments indicate that the TeERR protein shares an overall identity of 65%–82% with other known ERR homologues, and is most closely related to that of Nasonia vitripennis (Hymenoptera: Pteromalidae) and Apis mellifera (Apidae). Real-time quantitative reverse transcription-polymerase chain reaction was performed to compare the TeERR mRNA expression level at the whole body and gonad during T. emma development. The data revealed that TeERR mRNA is differentially expressed during T. emma development, with the highest expression level in embryos and the lowest in the body of late-instar larvae. The levels of TeERR transcripts also varied throughout gonad development; interestingly testicles had higher higher expression levels than ovaries at every development stage. These results suggest that TeERR has potential significance in the regulation of development in T. emma, due to its expression during different developmental periods. PMID:21265615

  17. EMMA, a Recoil Mass Spectrometer for TRIUMF's ISAC-II Facility

    NASA Astrophysics Data System (ADS)

    Davids, Barry; EMMA Collaboration

    2016-09-01

    EMMA is a recoil mass spectrometer for TRIUMF's ISAC-II facility in the final stages of installation and commissioning. In this talk I will briefly review the spectrometer's design capabilities, describe recent progress in its installation and commissioning, and discuss plans for its initial experimental program. This work was supported by the Natural Sciences and Engineering Council of Canada. TRIUMF receives federal funds through a contribution agreement with the National Research Council of Canada.

  18. EMMA: An Extensible Mammalian Modular Assembly Toolkit for the Rapid Design and Production of Diverse Expression Vectors.

    PubMed

    Martella, Andrea; Matjusaitis, Mantas; Auxillos, Jamie; Pollard, Steven M; Cai, Yizhi

    2017-07-21

    Mammalian plasmid expression vectors are critical reagents underpinning many facets of research across biology, biomedical research, and the biotechnology industry. Traditional cloning methods often require laborious manual design and assembly of plasmids using tailored sequential cloning steps. This process can be protracted, complicated, expensive, and error-prone. New tools and strategies that facilitate the efficient design and production of bespoke vectors would help relieve a current bottleneck for researchers. To address this, we have developed an extensible mammalian modular assembly kit (EMMA). This enables rapid and efficient modular assembly of mammalian expression vectors in a one-tube, one-step golden-gate cloning reaction, using a standardized library of compatible genetic parts. The high modularity, flexibility, and extensibility of EMMA provide a simple method for the production of functionally diverse mammalian expression vectors. We demonstrate the value of this toolkit by constructing and validating a range of representative vectors, such as transient and stable expression vectors (transposon based vectors), targeting vectors, inducible systems, polycistronic expression cassettes, fusion proteins, and fluorescent reporters. The method also supports simple assembly combinatorial libraries and hierarchical assembly for production of larger multigenetic cargos. In summary, EMMA is compatible with automated production, and novel genetic parts can be easily incorporated, providing new opportunities for mammalian synthetic biology.

  19. For Their Musical Uplift: Emma Azalia Hackley and Voice Culture in African American Communities

    ERIC Educational Resources Information Center

    Karpf, Juanita

    2011-01-01

    The noted African American soprano Emma Azalia Hackley (1867-1922) abandoned her concert career in the early twentieth century and began travelling throughout the United States, organizing community choruses and promoting community music making. She spent the remainder of her life engaged in what she called "musical social uplift", which entailed…

  20. Espectroscopia de candidatos a remanescentes de aglomerados abertos

    NASA Astrophysics Data System (ADS)

    Pavani, D. B.; Bica, E.; Ahumada, A. V.; Clariá, J. J.

    2003-08-01

    A pesquisa sobre remanescentes de aglomerados abertos tem despertado grande interesse. Seguindo esta tendência encontramos estudos teóricos e observacionais. Os primeiros baseiam-se em simulações numéricas buscando determinar fração de binárias e distâncias galatocêntricas, tempo de vida e conteúdo estelar. Estes estão relacionados à função inicial de massa e densidade de estrelas, ou seja, se ricos ou pobremente povoados, compactos ou esparsos. No caso observacional procuram-se identificar os remanescentes considerando-se que trazem estas assinaturas de seus percursores. No presente estudo empregamos espectroscopia para analisar oito concentrações pobremente povoadas, previamente classificadas como aglomerados abertos, sendo sete compactas e uma esparsa. As observações foram obtidas através do telescópio de 2,15 m do CASLEO em San Juan, Argentina, em turnos entre 2001 e 2003. Utilizamos uma câmara CCD contendo um chip Tektronics de 1024X1024 pixeis aliado a um espectrógrafo REOSC. O domínio espectral vai de 3700 a 7000 Å. As reduções foram realizadas no Observatório Astronômico de Córdoba (Argentina) usando pacotes IRAF padrões. Determinamos idades, avermelhamentos e tipos espectrais através de comparações com biblioteca de estrelas e de aglomerados. Em alguns casos nossos espectros estavam dominados por estrelas individuais às quais determinamos seus tipos espectrais. Aos oito objetos adicionamos mais cinco da literatura recente analisados via espectro ou diagrama cor-magnitude. O histograma resultante contém idades típicas entre 0.5 e 3 Ganos. Considerando que predominantemente estes objetos encontram-se na vizinhança solar e, portanto, não cruzaram muitas vezes o plano Galático esperamos que a diferença no tempo necessário para dissolução destes prováveis remanescentes seja em função de diferentes massas iniciais.

  1. Applying Item Response Theory to the Development of a Screening Adaptation of the Goldman-Fristoe Test of Articulation-Second Edition

    ERIC Educational Resources Information Center

    Brackenbury, Tim; Zickar, Michael J.; Munson, Benjamin; Storkel, Holly L.

    2017-01-01

    Purpose: Item response theory (IRT) is a psychometric approach to measurement that uses latent trait abilities (e.g., speech sound production skills) to model performance on individual items that vary by difficulty and discrimination. An IRT analysis was applied to preschoolers' productions of the words on the Goldman-Fristoe Test of…

  2. Application of semiautomatic measuring complex for ecological monitoring of marine aquatories (EMMA) in the study of coastal areas of the Black Sea

    NASA Astrophysics Data System (ADS)

    Goncharenko, Igor; Rostovtseva, Vera; Konovalov, Boris

    2017-04-01

    For monitoring of the ecological state of coastal waters it is often necessary to obtain data from board a moving ship or an airborne craft. We suggested using a three-channel passive optical device that enables to get the sea reflectance coefficient spectra from board a moving ship. The data of the measurements are processed then according to our original method, which is based on the intrinsic properties of the pure water absorption spectrum - water absorption step method (WASM). It gives us the possibility to suppress influence of the various weather and experiment conditions on the data quality and to obtain estimates of the absorption spectra of the sea waters under exploration. The retrieved spectra in its turn can be the source of information about water constituents concentration. Based on foregoing we developed a semiautomatic measurement complex EMMA (Ecological Monitoring of Marine Aquatories) operating from board a ship. It includes three hyperspectral photometers, the data from which are processed by special algorithm on base of WASM. In natural waters we can get estimates of phytoplankton pigments, "yellow substance" and suspended matter concentrations. EMMA is also provided by the flowing system of temperature and salinity measuring. The main results are the following: • The data from the new semiautomatic complex EMMA obtained during the operational monitoring of coastal waters aboard a moving vessel are given for two different regions of the Black Sea: the region at a river mouth at Adler and the region of two seas waters mixing at Feodosia. • Specially designed for the complex software based on the original algorithm for spectra calibration WASM, which can reduce the negative impact of adverse weather conditions (wind, cloudiness, sea roughness) on the results of evaluation of the composition of sea water (the concentration of particulate matter and DOM), is applied for the data processing. • Complex EMMA is used for rapid determination of

  3. "EMMA Study: a Brazilian community-based cohort study of stroke mortality and morbidity".

    PubMed

    Goulart, Alessandra Carvalho

    2016-01-01

    Stroke has a high burden of disability and mortality. The aim here was to evaluate epidemiology, risk factors and prognosis for stroke in the EMMA Study (Study of Stroke Mortality and Morbidity). Prospective community-based cohort carried out in Hospital Universitário, University of São Paulo, 2006-2014. Stroke data based on fatal and non-fatal events were assessed, including sociodemographic data, mortality and predictors, which were evaluated by means of logistic regression and survival analyses. Stroke subtype was better defined in the hospital setting than in the local community. In the hospital phase, around 70% were first events and the ischemic subtype. Among cerebrovascular risk factors, the frequency of alcohol intake was higher in hemorrhagic stroke (HS) than in ischemic stroke (IS) cases (35.4% versus 12.3%, P < 0.001). Low education was associated with higher risk of death, particularly after six months among IS cases (odds ratio, OR, 4.31; 95% confidence interval, CI, 1.34-13.91). The risk of death due to hemorrhagic stroke was greater than for ischemic stroke and reached its maximum 10 days after the event (OR: 3.31; 95% CI: 1.55-7.05). Four-year survival analysis on 665 cases of first stroke (82.6% ischemic and 17.4% hemorrhagic) showed an overall survival rate of 48%. At four years, the highest risks of death were in relation to ischemic stroke and illiteracy (hazard ratio, HR: 1.83; 95% CI: 1.26-2.68) and diabetes (HR: 1.45; 95% CI: 1.07-1.97). Major depression presented worse one-year survival (HR: 4.60; 95% CI: 1.36-15.55). Over the long term, the EMMA database will provide additional information for planning resources destined for the public healthcare system.

  4. Generation of membrane potential beyond the conceptual range of Donnan theory and Goldman-Hodgkin-Katz equation.

    PubMed

    Tamagawa, Hirohisa; Ikeda, Kota

    2017-09-01

    Donnan theory and Goldman-Hodgkin-Katz equation (GHK eq.) state that the nonzero membrane potential is generated by the asymmetric ion distribution between two solutions separated by a semipermeable membrane and/or by the continuous ion transport across the semipermeable membrane. However, there have been a number of reports of the membrane potential generation behaviors in conflict with those theories. The authors of this paper performed the experimental and theoretical investigation of membrane potential and found that (1) Donnan theory is valid only when the macroscopic electroneutrality is sufficed and (2) Potential behavior across a certain type of membrane appears to be inexplicable on the concept of GHK eq. Consequently, the authors derived a conclusion that the existing theories have some limitations for predicting the membrane potential behavior and we need to find a theory to overcome those limitations. The authors suggest that the ion adsorption theory named Ling's adsorption theory, which attributes the membrane potential generation to the mobile ion adsorption onto the adsorption sites, could overcome those problems.

  5. Determining k channel activation curves from k channel currents often requires the goldman-hodgkin-katz equation.

    PubMed

    Clay, John R

    2009-01-01

    Potassium ion current in nerve membrane, I(K), has traditionally been described by I(K) = g(K)(V - E(K)), where g(K) is the K ion conductance, V is membrane potential and E(K) is the K(+) Nernst potential. This description has been unchallenged by most investigators in neuroscience since its introduction almost 60 years ago. The problem with the I(K) approximately (V - E(K)) proportionality is that it is inconsistent with the unequal distribution of K ions in the intra- and extracellular bathing media. Under physiological conditions the intracellular K(+) concentration is significantly higher than the extracellular concentration. Consequently, the slope conductance at potentials positive to E(K) cannot be the same as that for potentials negative to E(K), as the linear proportionality between I(K) and (V - E(K)) requires. Instead I(K) has a non-linear dependence on (V - E(K)) which is well described by the Goldman-Hodgkin-Katz equation. The implications of this result for K(+) channel gating and membrane excitability are reviewed in this report.

  6. Construção de um catálogo de aglomerados abertos para estudo da dinâmica da estrutura espiral da Galáxia

    NASA Astrophysics Data System (ADS)

    Carlos, I. M.; Lépine, J. R. D.

    2003-08-01

    Os aglomerados abertos são objetos de grande valor para o estudo da dinâmica da Galáxia devido esses objetos terem uma faixa de idade relativamente ampla. O trabalho visa estudar a dinâmica da estrutura espiral da Galáxia principalmente através do uso desses aglomerados, uma vez que o estudo da cinemática desses objetos é fundamental para esse objetivo. Nosso grupo trabalha no sentido de construir uma base de dados de aglomerados abertos contendo coordenadas, distância, idade, movimentos próprios e velocidades radiais e já disponibiliza uma nova versão do catálogo de aglomerados abertos o qual é uma compilação de edições anteriores, principalmente Lynga (1987), Mermilliod (1995) e ESO-B (Lauberts 1982). Nossa amostra possui cerca de 1630 aglomerados, mas nem todos os parâmetros acima citados foram determinados em sua totalidade. Para determinarmos esses parâmetros, derivamos as cores intrínsecas das estrelas membro de cada aglomerado a partir de seus tipos espectrais (busca feita no SIMBAD) obtendo assim o excesso de cor individual. A distribuição dos excessos de cor foi então utilizada para derivarmos o avermelhamento médio para cada aglomerado. De maneira similar, os tipos espectrais foram usados para estimar as magnitudes absolutas, e com as magnitudes absolutas e aparentes determinamos a respectiva distribuição do módulo de distância e finalmente a distância. Para determinar as idades foram confeccionados os diagramas cor-magnitude das estrelas de cada aglomerado onde foram superpostas a Seqüência Principal de Idade Zero (ZAMS). Superpomos a ZAMS de Schmidt-Kaler e isócronas de composição solar. Essas isócronas foram usadas para determinação das idades dos aglomerados. Uma vez que não temos ainda resultados finais, apresentamos então alguns diagramas cor-magnitude os quais foram usados para determinação, principalmente, da distância e idade dos aglomerados.

  7. eMedication Meets eHealth with the Electronic Medication Management Assistant (eMMA).

    PubMed

    Tschanz, Mauro; Dorner, Tim Lucas; Denecke, Kerstin

    2017-01-01

    A patient's healthcare team is often missing a complete overview on the prescribed and dispensed medication. This is due to an inconsistent information flow between the different actors of the healthcare system. Often, only the patient himself knows exactly which drugs he is actually taking. Our objective is to exploit different eHealth technologies available or planned in Switzerland to improve the information flow of the medication data among the stakeholder and to support the patient in managing his medication. This work is embedded in the "Hospital of the Future Live" project, involving 16 companies and 6 hospitals in order to develop IT solutions for future optimized health care processes. A comprehensive set of requirements was collected from the different actors and project partners. Further, specifications of the available or planned eHealth infrastructure were reviewed to integrate relevant technologies into a coherent concept. We developed a concept that combines the medication list and an eHealth platform. The resulting electronic medication management assistant (eMMA) designed for the patient provides the current medication plan at any time and supports by providing relevant information through a conversational user interface. In Switzerland, we still need a bridging technology to combine the medication information from the electronic patient record with the medication plan's associated QR-Code. The developed app is intended to provide such bridge and demonstrates the usefulness of the eMediplan. It enables the patient to have all data regarding his medication on his personal mobile phone and he can - if necessary - provide the current medication to the health professional.

  8. Glycogen synthase kinase-3--a promising therapeutic target: Dr Hagit Eldar-Finkelman interviewed by Emma Quigley.

    PubMed

    Eldar-Finkelman, Hagit

    2006-04-01

    Dr Hagit Eldar-Finkelman (Sackler School of Medicine, Israel) was interviewed by Emma Quigley (Commissioning Editor, Expert Opinion on Therapeutic Targets) on 16th February 2006. Born in Jerusalem, Dr Eldar-Finkelman received her BSc in Chemistry in 1984 and both her MSc in Physical Chemistry (1986) and PhD in Life Science (1993) from the Weizmann Institute of Science. She was a recipient of the British Council Award, which allowed her to conduct research in biological nuclear magnetic resonance at the University of Oxford in the laboratory of Professor George K Radda. Following postdoctoral work at the School of Medicine of the University of Washington with Nobel Laureate Professor Edwin G Krebs, she became an Assistant Professor in the Department of Medicine at Harvard Medical School. Dr Eldar-Finkelman joined the Sackler School of Medicine at Tel Aviv University in 1999. Dr Eldar-Finkelman's research focuses on the molecular mechanisms regulating the protein kinase glycogen synthase kinase-3 (GSK-3), and their implications in negative regulation of signalling pathways. In particular, her work aims to develop specific inhibitors for GSK-3 and to test their functions in vitro and in vivo, considering the concept that such inhibitors may be useful in insulin resistance and Type 2 diabetes. These studies provide a conceptual basis for development of GSK-3 inhibitors and may lead to design of small molecules for treatment of diabetes and or neurodegenerative disorders.

  9. Cochlear potential difference between endolymph fluid and the hair cell's interior: a retold interpretation based on the Goldman equation.

    PubMed

    Kurbel, Sven; Borzan, Vladimir; Golem, Hilda; Dinjar, Kristijan

    2017-02-01

    Reported cochlear potential values of near 150 mV are often attributed to endolymph itself, although membrane potentials result from ion fluxes across the adjacent semipermeable membranes due to concentration gradients. Since any two fluids separated by a semipermeable membrane develop potential due to differences in solute concentrations, a proposed interpretation here is that positive potential emanates from the Reissner membrane due to small influx of sodium from perilymph to endolymph. Basolateral hair cell membranes leak potassium into the interstitial fluid and this negative potential inside hair cells further augments the electric gradient of cochlear potential. Taken together as a sum, these two potentials are near the reported values of cochlear potential. This is based on reported data for cochlear fluids used for the calculation of Nernst and Goldman potentials. The reported positive potential of Reissner membrane can be explained almost entirely by the traffic of Na+ that enters endolymph through this membrane. At the apical membrane of hair cells, acoustic stimulation modulates stereocillia permeability to potassium. Potassium concentration gradients on the apical membrane are low (the calculated Nernst value is <+3 mV), suggesting that the potassium current is not caused by the local potassium concentration gradient, but an electric field between the positive sodium generated potential on the Reissner membrane and negative inside hair cells. Potassium is forced by this overall electric field to enter hair cells when stereocilia are permeable due to mechanical bending. Copyright© by the Medical Assotiation of Zenica-Doboj Canton.

  10. Analysis of the question–answer service of the Emma Children’s Hospital information centre

    PubMed Central

    Heinen, Richard C.; Heymans, Hugo S. A.

    2010-01-01

    The information centre of the Emma Children’s Hospital AMC (EKZ AMC) is a specialised information centre where paediatric patients and persons involved with the patient can ask questions about all aspects of disease and its social implications. The aim of the study was to evaluate the question–answer service of this information centre in order to determine the role of a specialised information centre in an academic children’s hospital, identify the appropriate resources for the service and potential positive effects. For this purpose, a case management system was developed in MS ACCESS. The characteristics of the requester and the question, the time it took to answer questions, the information sources used and the extent to which we were able to answer the questions were registered. The costs of the service were determined. We analysed all questions that were asked in the year 2007. Fourteen hundred thirty-four questions were asked. Most questions were asked by parents (23.3%), healthcare workers (other than nurses; 16.5%) and nurses (15.3%). The scope of the most frequently asked questions include disease (20.2%) and treatment (13.0%). Information on paper was the main information source used. Most questions could be solved within 15 min. Twelve percent to 28% of total working hours are used for the question–answer service. Total costs including staff salary are rather large. In conclusions, taking over the task of providing additional medical information and by providing readily available, good quality information that healthcare professionals can use to inform their patients will lead to less time investment of these more expensive staff members. A specialised information service can anticipate on the information need of parents and persons involved with the paediatric patient. It improves information by providing with relatively simple resources that has the potential to improve patient and parent satisfaction, coping and medical results. A specialised

  11. Stent

    MedlinePlus

    ... of coronary artery disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ... Atherosclerotic peripheral arterial disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  12. 75 FR 485 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-05

    ... Municipal Market Access System (EMMA[supreg]) December 23, 2009. On July 14, 2009, the Municipal Securities... Municipal Market Access System (EMMA[supreg]). The proposed rule change was published for comment in the... Municipal Market Access system (``EMMA'') (as amended, the ``proposed rule change''). The proposed rule...

  13. The role of vasoactive intestinal peptide in neuroprotection: Professor Illana Gozes is interviewed by Emma Quigley.

    PubMed

    Gozes, Illana

    2007-06-01

    Professor Illana Gozes was interviewed by Emma Quigley (Senior Editor, Expert Opinion) on 17(th) April 2007. Professor Illana Gozes BSc, PhD holds the titles of Professor of Clinical Biochemistry; The Lily and Avraham Gildor Chair for the Investigation of Growth Factors; Director of Adams Super Center for Brain Studies and Levi-Edersheim-Gitter fMRI Institute; Head of the Dr Diana and Zelman Elton (Elbaum) Laboratory for Molecular Neuroendocrinology, Tel Aviv University and Chief Scientific Officer, Allon Therapeutics, Inc., Vancouver BC, Canada. Professor Gozes has served as a member (or chair) of several faculty, university or national and international committees and she currently serves on the Board of Directors of Allon Therapeutics, the Scientific Review Board of the ISOA, and is the Editor-in-Chief of the Journal of Molecular Neuroscience. Professor Gozes has received a number of scientific awards for her work including the Landau Award for an excellent PhD dissertation, the Juludan Prize and the Teva Founders Prize for exceptional scientific studies that may lead to biotechnology developments as well as the Bergmann Prize and the Neufeld award for outstanding/leading US-Israel BSF grant proposals, and has published extensively in the fields of molecular neuroscience and neuroprotection (> 200 scientific manuscripts). She is co-inventor of > 15 patents and applications, including the composition of matter patent on AL-108 and AL-208, Allon's lead compounds. Professor Gozes received a BSc from Tel Aviv University, a PhD from The Weizmann Institute of Science and was a Weizmann Postdoctoral Fellow at Massachusetts Institute of Technology, Research Associate/Visiting Scientist at the Salk Institute and the Scripps Clinic and Research Foundation, a Senior Scientist/Associate Professor at the Weizmann Institute and a Fogarty-Scholar-in-Residence at the National Institutes of Health (USA). Professor Gozes directs a very active research laboratory at Tel Aviv

  14. 76 FR 58852 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Notice of Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... of Rule Change To Extend the Effective Date of the Amendment to the Continuing Disclosure Service of EMMA To Provide for the Posting of Credit Rating and Related Information on the EMMA Public Web Site... service of the MSRB's Electronic Municipal Market Access system (``EMMA'') to provide for the posting of...

  15. Relevance of estrogen-related receptor gene and ecdysone receptor gene in adult testis of the cricket Teleogryllus emma (Orthoptera: Gryllidae).

    PubMed

    Jin, Wenjie; Jia, Yishu; Tan, E; Xi, Gengsi

    2017-10-30

    Estrogen-related receptor gene (ERR) and ecdysone receptor gene (EcR) belong to the nuclear receptor gene superfamily, both of which are associated with the regulation of insect reproductive development. However, the relationship between ERR and EcR and whether ERR participates in the 20E signal pathway during male reproduction are unclear. In this paper, adult male crickets Teleogryllus emma Ohmschi & Matsumura were divided into the experimental group, negative group, and control group. Crickets of the experimental group were injected with TeERR or TeEcR-dsRNA, and those in the negative group received EGFP-dsRNA. The efficiency of TeERR and TeEcR-RNAi was detected in the experimental group. Furthermore, the transcription level, morphological characteristics as well as weight were analyzed in the TeERR or TeEcR knocked-down testis. Results showed that the expression level of TeERR or TeEcR was significantly down-regulated (P < 0.05) when treated with 2000 ng TeERR or TeEcR-dsRNA for 48 h. The expression level of TeERR could be down-regulated (P < 0.05) using TeEcR-RNAi and vice versa. TeERR and TeEcR-RNAi caused morphological changes in testes, but they had no obvious effect on weight (P > 0.05). These results indicate that TeERR and TeEcR are intimately related to each other. In addition, TeERR may be involved in the 20E signal pathway and maintain the function of adult cricket testis.

  16. Relevance of estrogen-related receptor gene and ecdysone receptor gene in adult testis of the cricket Teleogryllus emma (Orthoptera: Gryllidae)

    NASA Astrophysics Data System (ADS)

    Jin, Wenjie; Jia, Yishu; Tan, E.; Xi, Gengsi

    2017-12-01

    Estrogen-related receptor gene ( ERR) and ecdysone receptor gene ( EcR) belong to the nuclear receptor gene superfamily, both of which are associated with the regulation of insect reproductive development. However, the relationship between ERR and EcR and whether ERR participates in the 20E signal pathway during male reproduction are unclear. In this paper, adult male crickets Teleogryllus emma Ohmschi & Matsumura were divided into the experimental group, negative group, and control group. Crickets of the experimental group were injected with TeERR or TeEcR-dsRNA, and those in the negative group received EGFP-dsRNA. The efficiency of TeERR and TeEcR-RNAi was detected in the experimental group. Furthermore, the transcription level, morphological characteristics as well as weight were analyzed in the TeERR or TeEcR knocked-down testis. Results showed that the expression level of TeERR or TeEcR was significantly down-regulated ( P < 0.05) when treated with 2000 ng TeERR or TeEcR-dsRNA for 48 h. The expression level of TeERR could be down-regulated ( P < 0.05) using TeEcR-RNAi and vice versa. TeERR and TeEcR-RNAi caused morphological changes in testes, but they had no obvious effect on weight ( P > 0.05). These results indicate that TeERR and TeEcR are intimately related to each other. In addition, TeERR may be involved in the 20E signal pathway and maintain the function of adult cricket testis.

  17. Ambulatory Phlebectomy

    MedlinePlus

    ... of Mitchel Goldman Before and after - IPL - face solar lentigenes, melasma, brown spots Photo courtesy of Mitchel ... Mitchel Goldman Before and after - IPL: face, rosacea, solar lentigenes, and photodamage Photo courtesy of Mitchel Goldman ...

  18. Ritual encounters of the queer kind: a political analysis of jewish lesbian ritual innovation.

    PubMed

    Brettschneider, Marla

    2003-01-01

    SUMMARY Jewish feminist and queer engagement in Jewish life and Judaism are transforming the practices and foundational orientations of traditional modes. Jewish feminist, queer ritual innovation in particular is inspired by an array of secular and radical critical theories as much as it is by the historic concrete experiences of a diversity of Jews in different Jewish communities. It is important to hold all of us who are involved in religious ritual innovation responsible to the knowledges we have developed and learned in critical theory or we risk, even with the best of intentions and creativity, re-inscribing some of the very problems of traditional ontological norms that we might have originally sought to disrupt and subvert. This article looks specifically at examples of new "coming out" rituals for Jewish queers explored over time in the Jewish Queer Think Tank: honoring them as well as offering tools from secular critical theory to assist our work in keeping them accountable to our aspirations to both love and fundamentally transform Jewishness. Here I redefine the function of religious ritual itself in political terms as an identity-producing performance. As such I utilize social constructionist queer theories (i.e., Shane Phelan and Judith Butler), anarchists (i.e., Emma Goldman), and those involved in radical theatre (i.e., Augusto Boal) to articulate the revolutionary potential of ritual innovation.

  19. EMMA—mouse mutant resources for the international scientific community

    PubMed Central

    Wilkinson, Phil; Sengerova, Jitka; Matteoni, Raffaele; Chen, Chao-Kung; Soulat, Gaetan; Ureta-Vidal, Abel; Fessele, Sabine; Hagn, Michael; Massimi, Marzia; Pickford, Karen; Butler, Richard H.; Marschall, Susan; Mallon, Ann-Marie; Pickard, Amanda; Raspa, Marcello; Scavizzi, Ferdinando; Fray, Martin; Larrigaldie, Vanessa; Leyritz, Johan; Birney, Ewan; Tocchini-Valentini, Glauco P.; Brown, Steve; Herault, Yann; Montoliu, Lluis; de Angelis, Martin Hrabé; Smedley, Damian

    2010-01-01

    The laboratory mouse is the premier animal model for studying human disease and thousands of mutants have been identified or produced, most recently through gene-specific mutagenesis approaches. High throughput strategies by the International Knockout Mouse Consortium (IKMC) are producing mutants for all protein coding genes. Generating a knock-out line involves huge monetary and time costs so capture of both the data describing each mutant alongside archiving of the line for distribution to future researchers is critical. The European Mouse Mutant Archive (EMMA) is a leading international network infrastructure for archiving and worldwide provision of mouse mutant strains. It operates in collaboration with the other members of the Federation of International Mouse Resources (FIMRe), EMMA being the European component. Additionally EMMA is one of four repositories involved in the IKMC, and therefore the current figure of 1700 archived lines will rise markedly. The EMMA database gathers and curates extensive data on each line and presents it through a user-friendly website. A BioMart interface allows advanced searching including integrated querying with other resources e.g. Ensembl. Other resources are able to display EMMA data by accessing our Distributed Annotation System server. EMMA database access is publicly available at http://www.emmanet.org. PMID:19783817

  20. Cutting

    MedlinePlus

    ... Staying Safe Videos for Educators Search English Español Cutting KidsHealth / For Teens / Cutting What's in this article? ... Getting Help Print en español Cortarse What Is Cutting? Emma's mom first noticed the cuts when Emma ...

  1. Gaucher disease

    MedlinePlus

    Glucocerebrosidase deficiency; Glucosylceramidase deficiency; Lysosomal storage disease - Gaucher ... 2016:chap 86. Krasnewich DM, Sidransky E. Lysosomal storage diseases. In: Goldman L, Schafer AI, eds. Goldman- ...

  2. Deglaciation and postglacial timberline in the San Juan Mountains, Colorado

    USGS Publications Warehouse

    Carrara, P.E.; Mode, W.N.; Rubin, M.; Robinson, S.W.

    1984-01-01

    Lake Emma, which no longer exists because of a mining accident, was a tarn in a south-facing cirque near the headwaters of the Animas River in the San Juan Mountains of southwestern Colorado. During the Pinedale glaciation, this area was covered by a large transection glacier centered over the Lake Emma region. Three radiocarbon dates on basal organic sediment from Lake Emma indicate that by ca. 15,000 yr B.P. this glacier, one of the largest in the southern Rocky Mountains, no longer existed. Twenty-two radiocarbon dates on Picea and Abies krummholz fragments in the Lake Emma deposits indicate that from ca. 9600 to 7800 yr B.P., from 6700 to 5600 yr B.P., and at 3100 yr B.P. the krummholz limit was at least 70 m higher than present. These data, in conjunction with Picea:Pinus pollen ratios from both the Lake Emma site and the Hurricane Basin site of J. T. Andrews, P. E. Carrara, F. B. King, and R. Struckenrath (1975, Quaternary Research 5, 173-197) suggest than from ca. 9600 to 3000 yr B.P. timberline in the San Juan Mountains was higher than present. Cooling apparently began ca. 3000 yr B.P. as indicated by decreases in both the percentage of Picea pollen and Picea:Pinus pollen ratios at the Hurricane Basin site (Andrews et al., 1975). Cooling is also suggested by the lack of Picea or Abies fragments younger than 3000 yr B.P. at either the Lake Emma or the Hurricane Basin site. ?? 1984.

  3. Hemophilia

    MedlinePlus

    ... disorders: coagulation factor deficiencies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  4. Donath-Landsteiner test

    MedlinePlus

    ... and intravascular hemolytic anemias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  5. Congenital antithrombin III deficiency

    MedlinePlus

    ... Thrombotic disorders: hypercoagulable states. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  6. Factor II deficiency

    MedlinePlus

    ... disorders: coagulation factor deficiencies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  7. Congenital afibrinogenemia

    MedlinePlus

    ... disorders: coagulation factor deficiencies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  8. Blood clots

    MedlinePlus

    ... Thrombotic disorders: hypercoagulable states. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  9. Factor X deficiency

    MedlinePlus

    ... disorders: coagulation factor deficiencies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  10. Hemoglobinopathy

    MedlinePlus

    ... disease and associated hemoglobinopathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  11. Factor XII (Hageman factor) deficiency

    MedlinePlus

    ... disorders: coagulation factor deficiencies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  12. Factor VII deficiency

    MedlinePlus

    ... disorders: coagulation factor deficiencies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  13. Bleeding disorders

    MedlinePlus

    ... disorders: coagulation factor deficiencies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  14. Von Willebrand disease

    MedlinePlus

    ... platelet and vascular function. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  15. Mediastinal tumor

    MedlinePlus

    ... wall, pleura, and mediastinum. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  16. Multiple mononeuropathy

    MedlinePlus

    Mononeuritis multiplex; Mononeuropathy multiplex; Multifocal neuropathy; Peripheral neuropathy - mononeuritis multiplex ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  17. Peripheral neuropathy

    MedlinePlus

    ... peripheral; Neuritis - peripheral; Nerve disease; Polyneuropathy; Chronic pain - peripheral neuropathy ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  18. Glanzmann disease

    MedlinePlus

    ... platelet and vascular function. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  19. Congenital spherocytic anemia

    MedlinePlus

    ... cells and bleeding disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  20. B-cell leukemia/lymphoma panel

    MedlinePlus

    ... Connors JM. Hodgkin lymphoma. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ... Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  1. Proceedings of the Summer Equatorial Experiment Data Review Meeting, 18 March 1980,

    DTIC Science & Technology

    1980-11-01

    longer wavelengths that approach the ion gyroradius. Huba and Ossakow - and Goldman and Sperling "l have shown that electron viscosity (from electron...Inhomogeneous Plasmas," Phys. Fluids, Vol. 22, No. 7, pp. 1349-1354 (July 1979). 13. Goldman, S. R. and J. L. Sperling , "Aspects of Late-Time...from that of Sperling and Goldman l1 because of a different definition of the thermal velocity. Based upon these assumptions, we obtain the following

  2. Adjustment and Validation of the Mathematical Prediction Model for Sweat Rate, Heart Rate and Body Temperature under Outdoor Conditions

    DTIC Science & Technology

    1986-11-01

    Predicting rectal temperature response to work environment and clothing. J. Pppl . PhysioL. 32: 812-822, 1972. 3. Givoni B., Goldman RF: Predicting...heart rote response to work, environment and clothing. J. PppL . PhysioL. 34: 201-204, 1973. 4. Givoni B., Goldman RF: Predicting effects of heat...expenditure with loads while standing or walking very slowly. J. Pppl . Physlol. 43: 477-581, 1877. G. Shapiro Y., Pandolf KB., Breckenridge JR., Goldman RF

  3. Kwashiorkor

    MedlinePlus

    ... total calories), and protein (12% of total calories). Alternative Names ... PA: Elsevier; 2016:chap 456. Manary MJ, Trehan I. Protein-energy malnutrition. In: Goldman L, Schafer AI, eds. Goldman's ...

  4. Aortic insufficiency

    MedlinePlus

    ... Heart valve - aortic regurgitation; Valvular disease - aortic regurgitation; AI - aortic insufficiency ... BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  5. Taking medicines to treat tuberculosis

    MedlinePlus

    Tuberculosis - medicines; DOT; Directly observed therapy; TB - medicines ... Ellner JJ. Tuberculosis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 324. ...

  6. Mallory-Weiss tear

    MedlinePlus

    ... the liver and problems with blood clotting make future bleeding episodes more likely to occur. ... Jensen DM. Gastrointestinal hemorrhage. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  7. Malignancy

    MedlinePlus

    ... Cancer biology and genetics. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 181. National Cancer Institute. NCI dictionary of cancer terms. Cancer.gov ...

  8. Aspiration

    MedlinePlus

    Davidson NE. Breast cancer and benign breast disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 198. Martin P. Approach to the patient ...

  9. Aging changes in the breast

    MedlinePlus

    ... this page: //medlineplus.gov/ency/article/003999.htm Aging changes in the breast To use the sharing ... chap 198. Walston JD. Common clinical sequelae of aging. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  10. Enteral nutrition - child - managing problems

    MedlinePlus

    ... page: //medlineplus.gov/ency/patientinstructions/000164.htm Enteral nutrition - child - managing problems To use the sharing features ... trouble breathing, call 911. References Mcclave SA. Enteral nutrition. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  11. Vitamin B12 level

    MedlinePlus

    ... 21. Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman's Cecil ... first to achieve this important distinction for online health information and services. Learn more about A.D. ...

  12. Arterial insufficiency

    MedlinePlus

    Hansson GK, Hamsten A. Atherosclerosis, thrombosis, and vascular biology. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 70. Libby P. The vascular biology of atherosclerosis. In: Mann DL, Zipes DP, Libby ...

  13. Angina

    MedlinePlus

    Boden WE. Angina pectoris and stable ischemic heart disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... PA: Elsevier Saunders; 2016:chap 72. Morrow DA, Boden WE. Stable ischemic heart disease. In: Mann DL, ...

  14. Bursitis

    MedlinePlus

    ... be ordered include: Removing fluid from the bursa Culture of the fluid Ultrasound MRI Treatment Your provider ... JJ. Bursitis, tendinitis, and other periarticular disorders of sports medicine. In: Goldman L, Schafer AI, eds. Goldman- ...

  15. Tumor

    MedlinePlus

    Black AR, Cowan KH. Cancer biology and genetics. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 181. Kumar V, Abbas AK, Aster JC. Neoplasia. ...

  16. Phosphorus in diet

    MedlinePlus

    ... 23115811 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Minerals Read more NIH MedlinePlus Magazine Read more Health Topics A-Z Read more A.D.A. ...

  17. Folic acid - test

    MedlinePlus

    ... 32. Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Acid Read more NIH MedlinePlus Magazine Read more Health Topics A-Z Read more A.D.A. ...

  18. High potassium level

    MedlinePlus

    ... level is very high, or if you have danger signs, such as changes in an ECG . Emergency ... Seifter JL. Potassium disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  19. Allergies - overview

    MedlinePlus

    ... used to treat food allergies because of the danger of a severe reaction. Allergy shots may need ... allergic or immunologic disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  20. Hypovolemic shock

    MedlinePlus

    ... the person's position unless they are in immediate danger. Do not give fluids by mouth. If person ... the patient with shock. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  1. Thromboangiitis obliterans

    MedlinePlus

    ... or feet: Ultrasound of the extremity, called plethysmography Doppler ultrasound of the extremity Blood tests for other ... chap 79. Stone JH. The systemic vasculitudes. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ...

  2. Hepatic vein obstruction (Budd-Chiari)

    MedlinePlus

    ... include: CT scan or MRI of the abdomen Doppler ultrasound of the liver veins Liver biopsy Liver ... SC. Vascular diseases of the gastrointestinal tract. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ...

  3. Dealing with chronic cancer

    MedlinePlus

    ... enjoying the present instead of worrying about the future. Focus on the small things that bring you ... E. The chronic leukemias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  4. Angiodysplasia of the colon

    MedlinePlus

    ... are likely to have more bleeding in the future. The outlook remains good if the bleeding is ... of the gastrointestinal tract. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: ...

  5. Cytomegalovirus (CMV) infection

    MedlinePlus

    ... If your immune system becomes weakened in the future, this virus may have the chance to reactivate, ... 140. Drew WL. Cytomegalovirus. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  6. Deciding about treatments that prolong life

    MedlinePlus

    ... you are receiving or may need in the future. Learn about the treatments and how they would ... patients and their families. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  7. Sydenham chorea

    MedlinePlus

    ... The provider may also prescribe antibiotics to prevent future RF infections. This is called preventive antibiotics, or ... AE. Other movement disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  8. Duchenne muscular dystrophy

    MedlinePlus

    ... and gene therapy may be used in the future. The use of steroids and the lack of ... Selcen D. Muscle diseases. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  9. Preeclampsia

    MedlinePlus

    ... preeclampsia makes a woman a higher risk for future problems such as: Heart disease Diabetes Kidney disease ... medical problems in pregnancy. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  10. Tendinitis

    MedlinePlus

    ... ability to function properly, improve healing, and prevent future injury. In rare cases, surgery is needed to ... disorders and sports medicine. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  11. Intracardiac electrophysiology study (EPS)

    MedlinePlus

    ... rhythm Determine whether you are at risk for future heart events, especially sudden cardiac death See if ... patient with suspected arrhythmia. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  12. Alzheimer disease

    MedlinePlus

    ... likely need to plan for their loved one's future care. The final phase of the disease may ... disease and other dementias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  13. Emma Elgqvist | NREL

    Science.gov Websites

    Energy Opportunities, Society of Telecommunication Engineers Cable-Tec Expo (2016) Automotive Lithium-ion Federal Tax Incentives for Battery Storage Systems, NREL Fact Sheet (2017) Portfolio Analysis of Renewable Battery (LIB) Supply Chain and U.S. Competitiveness Considerations, NREL Technical Report (2015) REopt: A

  14. Alcoholic ketoacidosis

    MedlinePlus

    Tests may include: Arterial blood gases (measures the acid/base balance and oxygen level in blood) Blood alcohol ... PA: Elsevier Saunders; 2014:chap 185. Seifter JL. Acid-base disorders. In: Goldman L, Schafer AI, eds. Goldman- ...

  15. Thiamin

    MedlinePlus

    ... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  16. Riboflavin

    MedlinePlus

    ... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  17. Vitamin B12

    MedlinePlus

    ... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  18. Vitamin D

    MedlinePlus

    ... 25419853 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Accessed May 5, 2017. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  19. Vitamin K

    MedlinePlus

    ... 25057538 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  20. Zinc in diet

    MedlinePlus

    ... 25077263 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  1. Niacin

    MedlinePlus

    ... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  2. Vitamin B6

    MedlinePlus

    ... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  3. Vitamin E

    MedlinePlus

    ... 25077263 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  4. Beta-carotene blood test

    MedlinePlus

    ... 302. Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

  5. Anaerobic bacteria

    MedlinePlus

    Anaerobic bacteria are bacteria that do not live or grow when oxygen is present. In humans, these bacteria ... Brook I. Diseases caused by non-spore-forming anaerobic bacteria. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  6. Mononeuropathy

    MedlinePlus

    ... a nerve outside the brain and spinal cord ( peripheral neuropathy ). Mononeuropathy is most often caused by injury. Bodywide ( ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  7. Chronic inflammatory polyneuropathy

    MedlinePlus

    ... to nerves outside the brain or spinal cord ( peripheral neuropathy ). Polyneuropathy means several nerves are involved. CIDP often ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  8. Epilepsy - overview

    MedlinePlus

    ... or antiepileptic drugs), may reduce the number of future seizures: These drugs are taken by mouth. Which ... 23986299 . Wiebe S. The epilepsies. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  9. Inborn errors of metabolism

    MedlinePlus

    Metabolism - inborn errors of ... Bodamer OA. Approach to inborn errors of metabolism. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 205. Rezvani I, Rezvani GA. An ...

  10. Ascites

    MedlinePlus

    ... disease - ascites; ESLD - ascites Images Ascites with ovarian cancer, CT scan Digestive system organs References Garcia-Tsao G. Cirrhosis and its sequelae. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  11. Hypercalcemia - discharge

    MedlinePlus

    ... glands, hypercalcemia, and hypocalcemia. In Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; ... by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  12. Staph infections - hospital

    MedlinePlus

    ... promptly reporting any sign of wound infections Many hospitals encourage patients to ask their providers if they have washed their ... DP. Prevention and control of health care-associated infections. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  13. Catheter-associated UTI

    MedlinePlus

    ... UTI; Health care-associated UTI; Catheter-associated bacteriuria; Hospital acquired-UTI Images Bladder catheterization, female Bladder catheterization, male References Calfee DP. Prevention and control of health care-associated infections. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  14. Osteitis fibrosa

    MedlinePlus

    ... LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric . 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 63. Thakker RV. The parathyroid glands, hypercalcemia and hypocalcemia. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  15. Neuralgia

    MedlinePlus

    ... 2016:chap 107. Scadding JW, Koltzenberg M. Painful peripheral neuropathies. In: McMahon SB, Koltzenburg M, Tracey I, Turk ... PA: Elsevier Saunders; 2013:chap 65. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  16. Radial nerve dysfunction

    MedlinePlus

    ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ... Read more Hand Injuries and Disorders Read more Peripheral Nerve Disorders Read more A.D.A.M., Inc. is ...

  17. Bleeding during cancer treatment

    MedlinePlus

    Doroshow JH. Approach to the patient with cancer. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 179. National Cancer Institute website. Chemotherapy and you: support for people ...

  18. Radiation therapy

    MedlinePlus

    Doroshow JH. Approach to the patient with cancer. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 179. National Cancer Institute. Radiation therapy and you: support for people ...

  19. Metastasis

    MedlinePlus

    Doroshow JH. Approach to the patient with cancer. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 179. Rankin EB. Erler J. Giaccia AJ. The cellular microenvironment and ...

  20. Ulnar nerve dysfunction

    MedlinePlus

    ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ... Editorial team. Hand Injuries and Disorders Read more Peripheral Nerve Disorders Read more NIH MedlinePlus Magazine Read more A. ...

  1. Autonomic neuropathy

    MedlinePlus

    ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Editorial team. Autonomic Nervous System Disorders Read more Peripheral Nerve Disorders Read more NIH MedlinePlus Magazine Read more A. ...

  2. Cardiomyopathy

    MedlinePlus

    ... the myocardium and endocardium. In Goldman L, Schafer AI, eds. Goldman’s Cecil Medicine . 25th ed. Philadelphia, PA: ... failure: management and diagnosis. In Goldman L, Schafer AI, eds. Goldman’s Cecil Medicine . 25th ed. Philadelphia, PA: ...

  3. Radiation therapy -- skin care

    MedlinePlus

    ... References Doroshow JH. Approach to the patient with cancer. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 179. National Cancer Institute website. Radiation therapy and you: support for ...

  4. Cancer treatments

    MedlinePlus

    ... 2017. Doroshow JH. Approach to the patient with cancer. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 179. National Cancer Institute website. Types of cancer treatment. www.cancer. ...

  5. Lung disease

    MedlinePlus

    ... cell cancer - CT scan Secondhand smoke and lung cancer Yellow nail syndrome Respiratory system References Kraft M. Approach to the patient with respiratory disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  6. Jejunostomy feeding tube

    MedlinePlus

    ... in adult hospitalized patients. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 217. Read More Cerebral palsy Cystic fibrosis Esophageal cancer Failure to thrive HIV/AIDS Patient Instructions Crohn ...

  7. Myotonia congenita

    MedlinePlus

    ... the electrical activity of the muscles) Genetic testing Muscle biopsy Treatment Mexiletine is a medicine that treats symptoms of ... Elsevier Saunders; 2016:chap 99. Sarnat HB. Muscular dystrophies. In: Kliegman RM, ... D. Muscle diseases. In: Goldman L, Schafer AI, eds. Goldman's ...

  8. Differential Expression of Inward and Outward Potassium Currents in the Macrophage-like Cell Line J774.1

    DTIC Science & Technology

    1985-04-02

    skeletal muscle (Adrian, Hodgkin & Chandler, 1970), and nerve (Goldman & Schauf , 1973; Thompson, 1977). The general mathematical formalism describes the...594-609. Goldman, L. & Schauf , C. L. (1973) Quantitative description of sodium and potassium currents and computed action potentials in Myxicola giant

  9. Magnesium in diet

    MedlinePlus

    ... 23115811 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 218. National Institutes of Health. Magnesium: fact sheet for health professionals. Updated February ...

  10. Anaplastic thyroid cancer

    MedlinePlus

    ... M, Ladenson P. Thyroid. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 226. Lai SY, Mandel SJ, Weber RS. Management of thyroid neoplasms. In: Flint PW, Haughey BH, Lund LJ, et ...

  11. Evaluation of the McGrath MAC and Macintosh laryngoscope for tracheal intubation in 2000 patients undergoing general anaesthesia: the randomised multicentre EMMA trial study protocol

    PubMed Central

    Kriege, Marc; Alflen, Christian; Tzanova, Irene; Schmidtmann, Irene; Piepho, Tim; Noppens, Ruediger R

    2017-01-01

    Introduction The direct laryngoscopy technique using a Macintosh blade is the first choice globally for most anaesthetists. In case of an unanticipated difficult airway, the complication rate increases with the number of intubation attempts. Recently, McGrath MAC (McGrath) video laryngoscopy has become a widely accepted method for securing an airway by tracheal intubation because it allows the visualisation of the glottis without a direct line of sight. Several studies and case reports have highlighted the benefit of the video laryngoscope in the visualisation of the glottis and found it to be superior in difficult intubation situations. The aim of this study was to compare the first-pass intubation success rate using the (McGrath) video laryngoscope compared with conventional direct laryngoscopy in surgical patients. Methods and analysis The EMMA trial is a multicentre, open-label, patient-blinded, randomised controlled trial. Consecutive patients requiring tracheal intubation are randomly allocated to either the McGrath video laryngoscope or direct laryngoscopy using the Macintosh laryngoscope. The expected rate of successful first-pass intubation is 95% in the McGrath group and 90% in the Macintosh group. Each group must include a total of 1000 patients to achieve 96% power for detecting a difference at the 5% significance level. Successful intubation with the first attempt is the primary endpoint. The secondary endpoints are the time to intubation, attempts for successful intubation, the necessity of alternatives, visualisation of the glottis using the Cormack & Lehane score and percentage of glottic opening score and definite complications. Ethics and dissemination The project was approved by the local ethics committee of the Medical Association of the Rhineland Palatine state and Westphalia-Lippe. The results of this study will be made available in the form of manuscripts for publication and presentations at national and international meetings. Trial

  12. Treatment of complicated grief using virtual reality: a case report.

    PubMed

    Botella, C; Osma, J; Palacios, A García; Guillén, V; Baños, R

    2008-01-01

    This is the first work exploring the application of new technologies, concretely virtual reality, to facilitate emotional processing in the treatment of Complicated Grief. Our research team has designed a virtual reality environment (EMMA's World) to foster the expression and processing of emotions. In this study the authors present a description of EMMA's World, the clinical protocol, and a case report. The treatment program was applied in eight sessions. We present a brief description of the session agendas including the techniques used. We offer short-term (from pre-test to post-test) and long-term (2-, 6- and 12-month follow-ups) efficacy data. Our results offer preliminary support of the use of EMMA's World for the treatment of Complicated Grief.

  13. Glucose-6-phosphate dehydrogenase deficiency

    MedlinePlus

    G6PD deficiency; Hemolytic anemia due to G6PD deficiency; Anemia - hemolytic due to G6PD deficiency ... Gallagher PG. Hemolytic anemias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 161. Janz ...

  14. Meningitis - gram-negative

    MedlinePlus

    ... system and peripheral nervous system References Nath A. Meningitis: bacterial, viral, and other. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap ... D, Scheld WM. Acute meningitis. In: Bennett JE, Dolin R, Blaser MJ, eds. ...

  15. Meningitis - staphylococcal

    MedlinePlus

    ... system and peripheral nervous system References Nath A. Meningitis: bacterial, viral, and other. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap ... D, Scheld WM. Acute meningitis. In: Bennett JE, Dolin R, Blaser MJ, eds. ...

  16. Disseminated intravascular coagulation (DIC)

    MedlinePlus

    ... and vitamin K deficiency. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 175. Review Date 10/21/2017 Updated by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  17. Serum globulin electrophoresis

    MedlinePlus

    ... SV. Plasma cell disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 187. Review Date 2/11/2016 Updated by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  18. 5-HIAA

    MedlinePlus

    ... and the carcinoid syndrome. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 232. Review Date 8/15/2016 Updated by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  19. Porphyria

    MedlinePlus

    ... Hift RJ. The porphyrias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 210. Review Date 2/1/2017 Updated by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by ...

  20. The Inevitable War?

    DTIC Science & Technology

    2011-05-20

    69 67 Alan Bryman and Emma Bell , Business Research Methods, 2 ed. (Oxford: Oxford...University Press, USA, 2007), 727. Bryam and Bell define a dependant variable as “ a variable that is causally influenced by another variable.” As the...Pushing-for-Yuan-to-be-Global- Currency-But-Business-Leaders-Say-Not-Yet-114475409.html (accessed April 6, 2011). Bryman , Alan, and Emma Bell

  1. Endophthalmitis

    MedlinePlus

    ... JS, eds. Ophthalmology . 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 7.9. Yanoff M, Cameron JD. Diseases of the visual system. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 423. Review Date 8/26/2017 ...

  2. Cough

    MedlinePlus

    ... of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 30. Kraft M. Approach to the patient with respiratory disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 83. Review Date 5/21/2017 ...

  3. After chemotherapy - discharge

    MedlinePlus

    ... References Doroshow JH. Approach to the patient with cancer. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 179. Freifeld AG, Kaul DR. Infection in the patient with cancer. In: Niederhuber JE, Armitage JO, Doroshow JH, Kastan ...

  4. A Design of Innovative Engineering Drawing Teaching Materials

    NASA Astrophysics Data System (ADS)

    Mujiarto; Djohar, A.; Komaro, M.

    2018-02-01

    Good teaching is influenced by several things such as effective school leaders and skilled teachers who are able to use information communication technology as a medium of learning. The purpose of this research in general is to develop innovative teaching materials in the form of multimedia animation for engineering drawing in the field of technology and engineering at vocational high school. Research method used research and development (research and development / R & D). The results showed that the E-book Multimedia Animation Engineering Drawing (E-MMAED) is easy to possess and contains complete material. Students stated that the use of E-MMAED adds to learning motivation and improves learning outcomes (student competencies). We recommend that teachers apply E-MMAED as a learning medium and create other innovations to improve student competences.

  5. Autoimmune hepatitis

    MedlinePlus

    ... and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 90. Pawlotsky J-M. Chronic viral and autoimmune hepatitis. In: Goldman L, ... Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 149. ... Updated by: Michael M. Phillips, MD, Clinical Professor of Medicine, The George ...

  6. Beyond Words: Phonological Short-Term Memory and Syntactic Impairment in Specific Language Impairment

    ERIC Educational Resources Information Center

    Bishop, Dorothy V. M.

    2006-01-01

    The assessment of nonword repetition in children goes back at least to 1974, when the Goldman-Fristoe-Woodcock Auditory Skills Battery was published, including a subtest (Sound Mimicry) assessing nonword repetition (Goldman, Fristoe, & Woodcock, 1974). Nevertheless, it was not until 20 years later, when Gathercole and Baddeley (1990) reported a…

  7. Preventing infections when visiting

    MedlinePlus

    ... need.) When you visit a patient in the hospital, keep your hands away from your face. Cough or sneeze into a tissue or into the crease of your elbow, not into the air. References Calfee DP. Prevention and control of health care-associated infections. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  8. Children's Understanding and Knowledge of Conception and Birth: Comparing Children from England, the Netherlands, Sweden, and the United States

    ERIC Educational Resources Information Center

    Caron, Sandra L.; Ahlgrim, Carie Jo

    2012-01-01

    The present study replicated research conducted decades earlier (Goldman & Goldman, 1982a; Koch, 197480) on what children in the United States know about conception and birth compared to those in other countries. Specifically, response drawings by 48 six-year-old boys and girls from England, the Netherlands, Sweden, and the United States were…

  9. Capitol Day

    NASA Image and Video Library

    2009-02-19

    Stennis Space Center Director Gene Goldman visits with Mississippi Gov. Haley Barbour during NASA Day at the Capitol activities on Feb. 19. During the visit, Goldman presented the governor with a model of the J-2X rocket engine currently in development. Stennis engineers did early component testing for the new engine.

  10. 75 FR 12296 - Prohibited Transaction Exemptions and Grant of Individual Exemptions Involving: 2010-04, JPMorgan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    .... App. 1 (1996), transferred the authority of the Secretary of the Treasury to issue exemptions of the... Offer may be made by Goldman after Goldman has determined that such purchase is in the best interest of... purchase under the Offer; (2) The background of the Offer; (3) The methods and timing by which Plans may...

  11. The Contents of My Backpack

    ERIC Educational Resources Information Center

    Goldman, Arthur

    2004-01-01

    As Mr. Goldman empties his backpack, his philosophy of teaching spills out, along with an interesting assortment of odds and ends. In this article Mr. Goldman describes the contents of his L.L. Bean daypack with two large compartments in the back, a smaller forward compartment, and a little zippered pocket in the very front, along with his…

  12. Seasonal and geographical adaption of two field crickets in China (Orthoptera: Grylloidea: Gryllidae: Gryllinae: Teleogryllus).

    PubMed

    He, Zhuqing; Wang, Xiaoyin; Liu, Yuqing; Li, Kai

    2017-10-24

    Crickets of the genus Teleogryllus belong to Gryllidae, Orthoptera. Teleogryllus emma (Ohmachi and Matsumura) and T. occipitalis (Serville) are widely distributed in east Asia, but their distribution and life history have not been reported from China. We studied the seasonal and geographical adaptation by rearing these crickets and measuring specimens. The main results are as follows: T. emma belongs to short-day type, which means nymphs grow rapidly in short day conditions (LD 12:12); T. occipitalis belongs to long-day type, which means nymphs grow rapidly in long day conditions (LD 16:8). The nymphal growth rate accelerates with the increase of temperature by comparing their nymph developmental period at 25 and 30OC. T. emma is mainly distributed in the north of the Yangtze River, while T. occipitalis in the south of it. The body size decreases with the increase of latitude in both species, while the relative length of their ovipositor increases.

  13. Enabling Medical Device Interoperability for the Integrated Clinical Environment

    DTIC Science & Technology

    2016-02-01

    Pajic M, Mangharam R, Sokolsky O, Arney D, Goldman JM, Lee I. Model-Driven Safety Analysis of Closed - Loop Medical Systems. IEEE Transactions on...Manigel J, Osborn D, Roellike T, Weininger S, Westenskow D, “Development of a Standard for Physiologic Closed Loop Controllers in Medical Devices...3 2010. 27. Arney D, Pajic M, Goldman JM, Lee I, Mangharam R, Sokolsky O, “Toward Patient Safety in Closed - Loop Medical Device Systems,” In

  14. Nonhomogeneity Detection in CFAR Reference Windows Using the Mean-to-Mean Ratio Test

    DTIC Science & Technology

    2012-01-01

    function of spatially sampled clutter level estimate, RCA Review, 1968, 29, (3), pp. 414-464 3. Morris, G., ‘Airborne Pulsed Doppler Radar Systems...Electronic Systems, 1980, 16, pp. 115-118. 7. Goldman , H., and Bar-David, I., Analysis and application of the excision CFAR detec- tor, IEE Proceedings...Radar, Sonar & Navigation, 1988, 135F, pp. 563-575. 8. Goldman , H., Performance of the excision CFAR detector in the presence of interferers, IEE

  15. A comparison of high-resolution specific conductance-based end-member mixing analysis and a graphical method for baseflow separation of four streams in hydrologically challenging agricultural watersheds

    USGS Publications Warehouse

    Kronholm, Scott C.; Capel, Paul D.

    2015-01-01

    Quantifying the relative contributions of different sources of water to a stream hydrograph is important for understanding the hydrology and water quality dynamics of a given watershed. To compare the performance of two methods of hydrograph separation, a graphical program [baseflow index (BFI)] and an end-member mixing analysis that used high-resolution specific conductance measurements (SC-EMMA) were used to estimate daily and average long-term slowflow additions of water to four small, primarily agricultural streams with different dominant sources of water (natural groundwater, overland flow, subsurface drain outflow, and groundwater from irrigation). Because the result of hydrograph separation by SC-EMMA is strongly related to the choice of slowflow and fastflow end-member values, a sensitivity analysis was conducted based on the various approaches reported in the literature to inform the selection of end-members. There were substantial discrepancies among the BFI and SC-EMMA, and neither method produced reasonable results for all four streams. Streams that had a small difference in the SC of slowflow compared with fastflow or did not have a monotonic relationship between streamflow and stream SC posed a challenge to the SC-EMMA method. The utility of the graphical BFI program was limited in the stream that had only gradual changes in streamflow. The results of this comparison suggest that the two methods may be quantifying different sources of water. Even though both methods are easy to apply, they should be applied with consideration of the streamflow and/or SC characteristics of a stream, especially where anthropogenic water sources (irrigation and subsurface drainage) are present.

  16. Assessing the recharge process and importance of montane water to adjacent tectonic valley-plain groundwater using a ternary end-member mixing analysis based on isotopic and chemical tracers

    NASA Astrophysics Data System (ADS)

    Peng, Tsung-Ren; Zhan, Wen-Jun; Tong, Lun-Tao; Chen, Chi-Tsun; Liu, Tsang-Sen; Lu, Wan-Chung

    2018-03-01

    A study in eastern Taiwan evaluated the importance of montane water contribution (MC) to adjacent valley-plain groundwater (VPG) in a tectonic suture zone. The evaluation used a ternary natural-tracer-based end-member mixing analysis (EMMA). With this purpose, VPG and three end-member water samples of plain precipitation (PP), mountain-front recharge (MFR), and mountain-block recharge (MBR) were collected and analyzed for stable isotopic compositions (δ 2H and δ 18O) and chemical concentrations (electrical conductivity (EC) and Cl-). After evaluation, Cl- is deemed unsuitable for EMMA in this study, and the contribution fractions of respective end members derived by the δ 18O-EC pair are similar to those derived by the δ 2H-EC pair. EMMA results indicate that the MC, including MFR and MBR, contributes at least 70% (679 × 106 m3 water volume) of the VPG, significantly greater than the approximately 30% of PP contribution, and greater than the 20-50% in equivalent humid regions worldwide. The large MC is attributable to highly fractured strata and the steep topography of studied catchments caused by active tectonism. Furthermore, the contribution fractions derived by EMMA reflect the unique hydrogeological conditions in the respective study sub-regions. A region with a large MBR fraction is indicative of active lateral groundwater flow as a result of highly fractured strata in montane catchments. On the other hand, a region characterized by a large MFR fraction may possess high-permeability stream beds or high stream gradients. Those hydrogeological implications are helpful for water resource management and protection authorities of the studied regions.

  17. Identifying geochemical processes using End Member Mixing Analysis to decouple chemical components for mixing ratio calculations

    NASA Astrophysics Data System (ADS)

    Pelizardi, Flavia; Bea, Sergio A.; Carrera, Jesús; Vives, Luis

    2017-07-01

    Mixing calculations (i.e., the calculation of the proportions in which end-members are mixed in a sample) are essential for hydrological research and water management. However, they typically require the use of conservative species, a condition that may be difficult to meet due to chemical reactions. Mixing calculation also require identifying end-member waters, which is usually achieved through End Member Mixing Analysis (EMMA). We present a methodology to help in the identification of both end-members and such reactions, so as to improve mixing ratio calculations. The proposed approach consists of: (1) identifying the potential chemical reactions with the help of EMMA; (2) defining decoupled conservative chemical components consistent with those reactions; (3) repeat EMMA with the decoupled (i.e., conservative) components, so as to identify end-members waters; and (4) computing mixing ratios using the new set of components and end-members. The approach is illustrated by application to two synthetic mixing examples involving mineral dissolution and cation exchange reactions. Results confirm that the methodology can be successfully used to identify geochemical processes affecting the mixtures, thus improving the accuracy of mixing ratios calculations and relaxing the need for conservative species.

  18. Emergency Operations Center ribbon cutting

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Center Director Gene Goldman and special guests celebrate the opening of the site's new Emergency Operations Center on June 2. Participants included (l t r): Steven Cooper, deputy director of the National Weather Service Southern Region; Tom Luedtke, NASA associate administrator for institutions and management; Charles Scales, NASA associate deputy administrator; Mississippi Gov. Haley Barbour; Gene Goldman, director of Stennis Space Center; Jack Forsythe, NASA assistant administrator for the Office of Security and Program Protection; Dr. Richard Williams, NASA chief health and medical officer; and Weldon Starks, president of Starks Contracting Company Inc. of Biloxi.

  19. Emergency Operations Center ribbon cutting

    NASA Image and Video Library

    2009-06-02

    Center Director Gene Goldman and special guests celebrate the opening of the site's new Emergency Operations Center on June 2. Participants included (l t r): Steven Cooper, deputy director of the National Weather Service Southern Region; Tom Luedtke, NASA associate administrator for institutions and management; Charles Scales, NASA associate deputy administrator; Mississippi Gov. Haley Barbour; Gene Goldman, director of Stennis Space Center; Jack Forsythe, NASA assistant administrator for the Office of Security and Program Protection; Dr. Richard Williams, NASA chief health and medical officer; and Weldon Starks, president of Starks Contracting Company Inc. of Biloxi.

  20. Intraocular pressure and biomechanical corneal properties measure by ocular response analyser in patients with primary congenital glaucoma.

    PubMed

    Perucho-González, Lucía; Martínez de la Casa, Jose María; Morales-Fernández, Laura; Bañeros-Rojas, Paula; Saenz-Francés, Federico; García-Feijoó, Julían

    2016-08-01

    To measure the differences in corneal hysteresis (CH) and corneal resistance factor (CRF) in primary congenital glaucoma (PCG) and in control subjects using ocular response analyser (ORA) and also to compare intraocular pressure (IOP) measurements given by ORA against IOP given by Perkins tonometer, a handheld version of Goldman applanation tonometer (GAT), to determine correlation. One hundred and eighteen eyes of 78 patients with PCG (group I) and 103 eyes of 53 controls (group II) were evaluated using ORA. In all participants, IOP was measured using the Perkins tonometer. The ORA device uses applanation pressure peaks to generate the corneal-compensated IOP (IOPcc), which is reportedly independent of corneal thickness, and the measurement of Goldman-correlated IOP (IOPg), which is influenced by corneal thickness. The measures in group I were as follows: IOPcc 20.92 ± 5.33; IOPg 18.87 ± 6.67; CH 8.51 ± 2.25; CRF 9.85 ± 3.03; and IOP measured by Goldman 18.32 ± 5.13. The measures in group II were as follows: IOPcc 14.33 ± 2.91; IOPg 14.77 ± 3.00; CH 11.37 ± 1.61; CRF 11.02 ± 1.74; and IOP measured by Goldman 13.74 ± 2.42. The differences of all parameters compared between both groups were statistically significant (p < 0.001 for CH and for all IOP measures and p = 0.001 for CRF). The values of IOPcc, IOPg and IOP measured with Goldman were higher in group I than the values in group II. However, CH and CRF values were lower in group I. A decrease in CH and CRF has been observed in patients with PCG compared to controls. Future research should assess how these parameters are modified in PCG and whether they could provide more information about progression. © 2015 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  1. Road dust emissions from paved roads measured using different mobile systems.

    PubMed

    Pirjola, Liisa; Johansson, Christer; Kupiainen, Kaarle; Stojiljkovic, Ana; Karlsson, Hans; Hussein, Tareq

    2010-12-01

    Very few real-world measurements of road dust suspension have been performed to date. This study compares two different techniques (referred to as Sniffer and Emma) to measure road dust emissions. The main differences between the systems are the construction of the inlet, different instruments for recording particulate matter (PM) levels, and different loads on the wheel axes (the weight of Sniffer was much higher than that of Emma). Both systems showed substantial small-scale variations of emission levels along the road, likely depending on-road surface conditions. The variations observed correlated quite well, and the discrepancies are likely a result of variations in dust load on the road surface perpendicular to the driving direction that cause variations in the measurements depending on slightly different paths driven by the two vehicles. Both systems showed a substantial influence on the emission levels depending on the type of tire used. The summer tire showed much lower suspension than the winter tires (one nonstudded and one studded). However, the relative importance of the nonstudded versus studded tire was rather different. For the ratio of studded/nonstudded, Emma shows higher values on all road sections compared with Sniffer. Both techniques showed increased emission levels with increasing vehicle speed. When the speed increased from 50 to 80 km hr(-1), the relative concentrations increased by 30-170% depending on the tire type and dust load. However, for road sections that were very dirty, Sniffer showed a much higher relative increase in the emission level with the nonstudded tire. Sniffer's absolute concentrations were mostly higher than Emma's. Possible reasons for the differences are discussed in the paper. Both systems can be used for studying relative road dust emissions and for designing air quality management strategies.

  2. Estimation of different source contributions to sediment organic matter in an agricultural-forested watershed using end member mixing analyses based on stable isotope ratios and fluorescence spectroscopy.

    PubMed

    Derrien, Morgane; Kim, Min-Seob; Ock, Giyoung; Hong, Seongjin; Cho, Jinwoo; Shin, Kyung-Hoon; Hur, Jin

    2018-03-15

    The two popular source tracing tools of stable isotope ratios (δ 13 C and δ 15 N) and fluorescence spectroscopy were used to estimate the relative source contributions to sediment organic matter (SeOM) at five different river sites in an agricultural-forested watershed (Soyang Lake watershed), and their capabilities for the source assignment were compared. Bulk sediments were used for the stable isotopes, while alkaline extractable organic matter (AEOM) from sediments was used to obtain fluorescent indices for SeOM. Several source discrimination indices were fully compiled for a range of the SeOM sources distributed in the catchments of the watershed, which included soils, forest leaves, crop (C3 and C4) and riparian plants, periphyton, and organic fertilizers. The relative source contributions to the river sediment samples were estimated via end member mixing analysis (EMMA) based on several selected discrimination indices. The EMMA based on the isotopes demonstrated that all sediments were characterized by a medium to a high contribution of periphyton ranging from ~30% to 70% except for one site heavily affected by forest and agricultural fields with relatively high contributions of terrestrial materials. The EMMA based on fluorescence parameters, however, did not show similar results with low contributions from forest leaf and periphyton. The characteristics of the studied watershed were more consistent with the source contributions determined by the isotope ratios. The discrepancy in the EMMA capability for source assignments between the two analytical tools can be explained by the limited analytical window of fluorescence spectroscopy for non-fluorescent dissolved organic matter (FDOM) and the inability of AEOM to represent original bulk particulate organic matter (POM). Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Towards integrating tracer studies in conceptual rainfall-runoff models: recent insights from a sub-arctic catchment in the Cairngorm Mountains, Scotland

    NASA Astrophysics Data System (ADS)

    Soulsby, Chris; Dunn, Sarah M.

    2003-02-01

    Hydrochemical tracers (alkalinity and silica) were used in an end-member mixing analysis (EMMA) of runoff sources in the 10 km2 Allt a' Mharcaidh catchment. A three-component mixing model was used to separate the hydrograph and estimate, to a first approximation, the range of likely contributions of overland flow, shallow subsurface storm flow, and groundwater to the annual hydrograph. A conceptual, catchment-scale rainfall-runoff model (DIY) was also used to separate the annual hydrograph in an equivalent set of flow paths. The two approaches produced independent representations of catchment hydrology that exhibited reasonable agreement. This showed the dominance of overland flow in generating storm runoff and the important role of groundwater inputs throughout the hydrological year. Moreover, DIY was successfully adapted to simulate stream chemistry (alkalinity) at daily time steps. Sensitivity analysis showed that whilst a distinct groundwater source at the catchment scale could be identified, there was considerable uncertainty in differentiating between overland flow and subsurface storm flow in both the EMMA and DIY applications. Nevertheless, the study indicated that the complementary use of tracer analysis in EMMA can increase the confidence in conceptual model structure. However, conclusions are restricted to the specific spatial and temporal scales examined.

  4. Radioactive contamination of arthropods from different trophic levels in hilly and mountainous areas after the Fukushima Daiichi nuclear power plant accident.

    PubMed

    Tanaka, Sota; Hatakeyama, Kaho; Takahashi, Sentaro; Adati, Tarô

    2016-11-01

    In order to understand the influence of the Fukushima Daiichi nuclear power plant accident on the ecosystem in hilly and mountainous areas of Fukushima Prefecture, chronological changes in the levels of radiocesium in arthropod species were investigated. From 2012 to 2014, arthropods from different trophic levels were sampled and the air radiation dose rates at the sampling sites were analyzed. The air radiation dose rates showed a significant and constant reduction over the 2 years at the sampling sites in Fukushima. The median radiocesium concentration ( 134 Cs +  137 Cs) detected in the rice grasshopper, Oxya yezoensis, and the Emma field cricket, Teleogryllus emma, dropped continuously to 0.080 and 0.078 Bq/g fresh weight, respectively, in 2014. In contrast, no significant reduction in radioactive contamination was observed in the Jorô spider, Nephila clavata, in which the level remained at 0.204 Bq/g in 2014. A significant positive correlation between radiocesium concentration and the air radiation dose rate was observed in the rice grasshopper, the Emma field cricket and the Jorô spider. The highest correlation coefficient (ρ = 0.946) was measured in the grasshopper. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  5. Autumn MIST 2012

    NASA Astrophysics Data System (ADS)

    Fear, Robert; Woodfield, Emma

    2013-04-01

    Robert Fear and Emma Woodfield report on the Autumn MIST meeting, concerning the solar wind; magnetospheres of planets and comets; ionospheres, thermospheres and mesospheres and how these regions connect.

  6. Modeling and Simulation of Explosively Driven Electromechanical Devices

    NASA Astrophysics Data System (ADS)

    Demmie, Paul N.

    2002-07-01

    Components that store electrical energy in ferroelectric materials and produce currents when their permittivity is explosively reduced are used in a variety of applications. The modeling and simulation of such devices is a challenging problem since one has to represent the coupled physics of detonation, shock propagation, and electromagnetic field generation. The high fidelity modeling and simulation of complicated electromechanical devices was not feasible prior to having the Accelerated Strategic Computing Initiative (ASCI) computers and the ASCI developed codes at Sandia National Laboratories (SNL). The EMMA computer code is used to model such devices and simulate their operation. In this paper, I discuss the capabilities of the EMMA code for the modeling and simulation of one such electromechanical device, a slim-loop ferroelectric (SFE) firing set.

  7. 14. Photocopy of negative (original in possession of WACC), photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of negative (original in possession of WACC), photographer unknown, c.1908 EMMA AND NEIL ERICKSON IN FRONT OF BOARD AND BATTEN SOUTH WALL OF MAIN HOUSE - Faraway Ranch, Willcox, Cochise County, AZ

  8. 6 Tips to Avoid Medication Mistakes

    MedlinePlus

    ... marketing the Electronic Medication Management Assistant (EMMA), a programmable device that stores and dispenses prescription medication for ... Of Your Health Care Team (article) Consumer Educational Materials: What You Need to Know to Use Medicine ...

  9. Acute nephritic syndrome

    MedlinePlus

    ... Names Glomerulonephritis - acute; Acute glomerulonephritis; Nephritis syndrome - acute Images Kidney anatomy References Appel GB, Radhakrishnan J. Glomerular disorders and nephrotic syndromes. In: Goldman L, ...

  10. Membranous nephropathy

    MedlinePlus

    ... glomerulonephritis; Membranous GN; Extramembranous glomerulonephritis; Glomerulonephritis - membranous; MGN Images Kidney anatomy References Appel GB, Radhakrishnan J. Glomerular disorders and nephrotic syndromes. In: Goldman L, ...

  11. Superficial thrombophlebitis

    MedlinePlus

    ... up and moving about. Alternative Names Thrombophlebitis - superficial Images Superficial thrombophlebitis Superficial thrombophlebitis References Ginsberg JS. Peripheral venous disease. In: Goldman L, Schafer AI, ...

  12. 1. COMPARATIVE VIEW OF THREE RESIDENTIAL STRUCTURES, 203 1/2 TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. COMPARATIVE VIEW OF THREE RESIDENTIAL STRUCTURES, 203 1/2 TO 205 WHITTIER, BUILT IN 1905, NORTH FRONTS LOOKING SOUTH - Joseph & Emma May Hoover House, 203 1/2 West Whittier Avenue, Altoona, Blair County, PA

  13. Focal segmental glomerulosclerosis

    MedlinePlus

    ... Alternative Names Segmental glomerulosclerosis; Focal sclerosis with hyalinosis Images Male urinary system References Appel GB, Radhakrishnan J. Glomerular disorders and nephrotic syndromes In: Goldman L, ...

  14. Thrombophlebitis

    MedlinePlus

    ... thrombophlebitis. Alternative Names Phlebitis; Deep vein thrombosis - thrombophlebitis Images Deep venous thrombosis, iliofemoral Venous blood clot References Ginsberg JS. Peripheral venous disease. In: Goldman L, Schafer AI, ...

  15. 36. Photocopy of photograph (original in possession of Chiricahua National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. Photocopy of photograph (original in possession of Chiricahua National Monument), photographer unknown, c.1915 EMMA ERICKSON AND MRS. COLLINS ON BALCONY OF RANCH HOUSE - Faraway Ranch, Erickson-Riggs Ranch House, State Highway 181, Willcox, Cochise County, AZ

  16. 76 FR 17817 - Huron-Manistee Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-31

    ... FURTHER INFORMATION CONTACT: Steven Goldman, Designated Federal Official or Carrie Scott, Natural Resource...) Selection of a committee chairperson; (3) Review of materials explaining the processes for recommending and...

  17. 77 FR 76146 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Approving a Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ...-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Approving a Proposed Rule Change Consisting of Amendments To Streamline New Issue Information Submission Requirements Under MSRB Rules G-32..., and market information requirements); and the Electronic Municipal Market Access (``EMMA[supreg...

  18. Working Group 2 Summary:. Space Charge Effects in Bending Systems

    NASA Astrophysics Data System (ADS)

    Bohn, Courtlandt L.; Emma, Paul J.

    2000-12-01

    Participants in Working Group 2 included: Y. Batygin, C. Bohn, B. Carlsten, J. Ellison, P. Emma, Z. Huang, A. Kabel, R. Kishek, R. Li, P. Musumeci, S. Nagaitsev, J. Qiang, M. Reiser, A. Ruggerio, R. Warnock, and M. Zeitlin.

  19. 77 FR 26063 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Granting Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ... Disclosure Subscription Service, that make documents and related indexing information available on a current... indexing information obtained through submissions to the Primary Market Disclosure Service (the ``Primary... amendments thereto, together with related indexing information, provided by submitters through EMMA, for an...

  20. Abdominal girth

    MedlinePlus

    ... and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management . 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 7. Martin P. Approach to the patient with liver disease. In: Goldman ...

  1. Arrhythmias

    MedlinePlus

    ... sign of other heart problems, or an immediate danger to your health. ... patient with suspected arrhythmia. In: Goldman L, Schafer AI, eds. Goldman’s Cecil Medicine . 25th ed. Philadelphia, PA: ...

  2. Seasonal Stream Partitioning and Critical Zone Feedbacks within a Colorado River Headwater Basin

    NASA Astrophysics Data System (ADS)

    Carroll, R. W. H.; Bearup, L. A.; Williams, K. H.; Brown, W. S.; Dong, W.; Bill, M.

    2017-12-01

    Groundwater contribution to streams can modulate discharge response to climate extremes, thereby protecting ecosystem health and water supply for downstream users. However, much uncertainty exists on the role of groundwater contribution in snow-dominated, mountainous systems. To better understand seasonal stream source, we employ the empirical approach of end-member mixing analysis (EMMA) using a suite of natural chemical and isotopic observations within the East River; a headwater catchment of the Colorado River and recently designated as a Science Focus Area with Lawrence Berkeley National Laboratory. EMMA relies on principal component analysis to reduce the number of dimensions of variability (U-space) for use in hydrograph separation. The mixing model was constructed for the furthest downstream and most heavily characterized stream gauge in the study site (PH; 84.7 km2). Potential tracers were identified from PH discharge as near linear (Mg, Ca, Sr, U, SO4, DIC, δ2H and δ18O) with alternative groupings evaluated. The best model was able to describe 97% of the tracer variance in 2-dimensions with low error and lack of residual structure. U-space positioning resulted in seasonal stream water source contributions of rain (8-16%), snow (48-74%) and groundwater (18-42%). EMMA developed for PH did not scale across 10 nested sub-basins (ranging from 0.38 km2 to 69.9 km2). Differences in mixing ratios are attributable to feedbacks in the critical zone with a focus on (1) source rock contributions of SO4 and U; (2) biogeochemical processes of enhanced SO4 reduction in the floodplain sediments, (3) flow path length as expressed by carbonate weathering, and (4) enhanced groundwater contributions as related to snow distribution and ecosystem structure. EMMA is an initial step to elucidate source contributions to streamflow and address scalability and applicability of mixing processes in a complex, highly heterogeneous, snow-dominated catchment. Work will aid hydrologic

  3. A Child Becomes a Reader

    MedlinePlus

    ... support from C. Ralph Adler and Elizabeth Goldman, design support from Lisa T. Noonis, and production support from Robert Kozman, all of RMC Research Corporation. To order copies of this booklet, contact ...

  4. 75 FR 63884 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Approving Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... unfairly allows institutional and sophisticated investors to more easily access information about a... information directly to EMMA is a more efficient way of disseminating information to investors, noting that... in the level of investor protection provided by the MSRB's information systems and [[Page 63886...

  5. Transformer Specification Language: A System for Generating Analyzers and Its Applications

    DTIC Science & Technology

    2011-01-01

    like to thank present and former colleagues in PL group, Evan Driscoll, Aditya Thakur, Matt Elder, Tushar Sharma , Prathmesh Prabhu, Tycho Andersen, Emma...Robert Cohn, Robert Muth, Harish Patil, Artur Klauser, Geoff Lowney, Steven Wallace, Vijay Janapa Reddi, and Kim Hazelwood. Pin: building customized

  6. Adolescent literacy: learning and understanding content.

    PubMed

    Goldman, Susan R

    2012-01-01

    Learning to read--amazing as it is to small children and their parents--is one thing. Reading to learn, explains Susan Goldman of the University of Illinois at Chicago, is quite another. Are today's students able to use reading and writing to acquire knowledge, solve problems, and make decisions in academic, personal, and professional arenas? Do they have the literacy skills necessary to meet the demands of the twenty-first century? To answer these questions, Goldman describes the increasingly complex comprehension, reasoning skills, and knowledge that students need as they progress through school and surveys what researchers and educators know about how to teach those skills. Successfully reading to learn requires the ability to analyze, synthesize, and evaluate information from multiple sources, Goldman writes. Effective readers must be able to apply different knowledge, reading, and reasoning processes to different types of content, from fiction to history and science, to news accounts and user manuals. They must assess sources of information for relevance, reliability, impartiality, and completeness. And they must connect information across multiple sources. In short, successful readers must not only use general reading skills but also pay close attention to discipline-specific processes. Goldman reviews the evidence on three different instructional approaches to reading to learn: general comprehension strategies, classroom discussion, and disciplinary content instruction. She argues that building the literacy skills necessary for U.S. students to read comprehensively and critically and to learn content in a variety of disciplines should be a primary responsibility for all of the nation's teachers. But outside of English, few subject-area teachers are aware of the need to teach subject-area reading comprehension skills, nor have they had opportunities to learn them themselves. Building the capacity of all teachers to meet the literacy needs of today's students

  7. Beyond triage: the diagnostic accuracy of emergency department nursing staff risk assessment in patients with suspected acute coronary syndromes.

    PubMed

    Carlton, Edward Watts; Khattab, Ahmed; Greaves, Kim

    2016-02-01

    To establish the accuracy of emergency department (ED) nursing staff risk assessment using an established chest pain risk score alone and when incorporated with presentation high-sensitivity troponin testing as part of an accelerated diagnostic protocol (ADP). Prospective observational study comparing nursing and physician risk assessment using the modified Goldman (m-Goldman) score and a predefined ADP, incorporating presentation high-sensitivity troponin. A UK District ED. Consecutive patients, aged ≥18, with suspected cardiac chest pain and non-ischaemic ECG, for whom the treating physician determined serial troponin testing was required. 30-day major adverse cardiac events (MACE). 960 participants were recruited. 912/960 (95.0%) had m-Goldman scores recorded by physicians and 745/960 (77.6%) by nursing staff. The area under the curve of the m-Goldman score in predicting 30-day MACE was 0.647 (95% CI 0.594 to 0.700) for physicians and 0.572 (95% CI 0.510 to 0.634) for nursing staff (p=0.09). When incorporated into an ADP, sensitivity for the rule-out of MACE was 99.2% (95% CI 94.8% to 100%) and 96.7% (90.3% to 99.2%) for physicians and nurses, respectively. One patient in the physician group (0.3%) and three patients (1.1%) in the nursing group were classified as low risk yet had MACE. There was fair agreement in the identification of low-risk patients (kappa 0.31, 95% CI 0.24 to 0.38). The diagnostic accuracy of ED nursing staff risk assessment is similar to that of ED physicians and interobserver reliability between assessor groups is fair. When incorporating high-sensitivity troponin testing, a nurse-led ADP has a miss rate of 1.1% for MACE at 30 days. Controlled Trials Database (ISRCTN no. 21109279). Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  8. Anemia of chronic disease

    MedlinePlus

    ... ACD include: Autoimmune disorders , such as Crohn disease , systemic lupus erythematosus , rheumatoid arthritis , and ulcerative colitis Cancer , ... AOCD; ACD Images Blood cells References Bunn HF. Approach to the anemias. In: Goldman L, Schafer AI, ...

  9. Prostatitis - nonbacterial

    MedlinePlus

    ... ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 40. Kaplan SA. Benign prostatic hyperplasia and prostatitis. In: Goldman ... constitute endorsements of those other sites. Copyright 1997-2018, A.D.A.M., Inc. Duplication for commercial ...

  10. Essential thrombocythemia

    MedlinePlus

    ... leukemia (cancer that starts in the bone marrow) Polycythemia vera (bone marrow disease that leads to an ... PA: Elsevier Saunders; 2013:chap 68. Tefferi A. Polycythemia vera, essential thrombocythemia, and primary myelofibrosis. In: Goldman ...

  11. Pulmonary nocardiosis

    MedlinePlus

    ... you and listen to your lungs using a stethoscope. You may have abnormal lung sounds, called crackles. ... returning. Alternative Names Nocardiosis - pulmonary; Mycetoma; Nocardia Images Respiratory system References Southwick FS. Nocardiosis. In: Goldman L, ...

  12. Comment on 'Observation of intrinsic bistability in resonant-tunneling structures'

    NASA Technical Reports Server (NTRS)

    Sollner, T. C. L. G.

    1987-01-01

    It is suggested that the intrinsic bistability observed by Goldman et al. (1987) occurred not because of charging of the well, as is claimed, but because of oscillations in the negative-resistance region. A typical I-V curve for a double-barrier resonant-tunneling (DBRT) diode which is known to be oscillating is presented. In a reply to this comment, Goldman et al. show that the series resistance (of about 100 ohms) in Sollner's sample leads to extrinsic, rather than intrinsic, bistability. It is furthermore suggested that the mere presence of an oscillation does not in itself exclude intrinsic bistability in a DBRT structure. It is also noted that the intrinsic bistability and buildup of negative charge-space in a DBRT structure well has been demonstrated experimentally by Payling et al. (1987).

  13. Blood in the semen

    MedlinePlus

    ... 11th ed. Philadelphia, PA: Elsevier; 2016:chap 1. Kaplan SA. Benign prostatic hyperplasia and prostatitis. In: Goldman ... constitute endorsements of those other sites. Copyright 1997-2018, A.D.A.M., Inc. Duplication for commercial ...

  14. Loss of brain function - liver disease

    MedlinePlus

    ... FF, ed. Ferri's Clinical Advisor 2018 . Philadelphia, PA: Elsevier; 2018:577-579. Garcia-Tsao G. Cirrhosis and ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 153. Jakhete N, Kim AK. ...

  15. Hardening of the arteries

    MedlinePlus

    ... Hansson GK, Hamsten A. Atherosclerosis, thrombosis, and vascular biology. In: Goldman L, Schafer AI, eds. Goldman’s Cecil ... Saunders; 2016:chap 70. Libby P. The vascular biology of atherosclerosis. In: Mann DL, Zipes DP, Libby ...

  16. Goiter - simple

    MedlinePlus

    ... In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric . 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 90. Kim M, Ladenson PW. Thyroid. In: Goldman L, Schafer ...

  17. How Is Pain Managed?

    MedlinePlus

    ... Goggins Lab Sol Goldman Center Discussion Board Pain Management Pain is a very common symptom in patients ... significantly reduce a patient’s quality of life. Proper management of this pain is therefore important, and patients ...

  18. Early Women Geography Educators, 1783-1932.

    ERIC Educational Resources Information Center

    Pittser, Sharan E.

    1999-01-01

    Discusses the contributions of women educators to the development of geography as a discipline, focusing on seven women: (1) Susanna Rowson; (2) Emma Hart Willard; (3) Sarah Sophia Cornell; (4) Ellen Churchill Semple; (5) Zonia Baber; (6) Erna Grassmuck Gilland; and (7) Esther Sanfrieda Anderson. (CMK)

  19. Insect bites and stings

    MedlinePlus

    ... eds. Auerbach's Wilderness Medicine . 7th ed. Philadelphia, PA: Elsevier; 2017:chap 43. Elston DM. Arthropods and leeches. ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 359. Otten EJ. Venomous animal ...

  20. Culture - duodenal tissue

    MedlinePlus

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. Dupont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Fritsche TR, Pritt BS. ...

  1. Crohn disease

    MedlinePlus

    ... eds. Current Surgical Therapy . 12th ed. Philadelphia, PA: Elsevier; 2017:164-171. Lichenstein GR. Inflammatory bowel disease. ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 141. Mahmoud NN, Bleier JIS, ...

  2. Giardia infection

    MedlinePlus

    ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 283. Haines CF, Sears CL. ... Gastrointestinal and Liver Disease . 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 110. Nash TE, Hill DR. ...

  3. Arteriogram

    MedlinePlus

    ... eds. Rutherford's Vascular Surgery . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 102. Goldstein LB. Approach to ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 406. Kern M. Catheterization and ...

  4. Hemoglobin derivatives

    MedlinePlus

    ... Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 43. Bunn HF. Approach to the ... eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 158. Christiani DC. Physical and ...

  5. Carotid artery stenosis -- self-care

    MedlinePlus

    ... Neurology in Clinical Practice . 7th ed. Philadelphia, PA: Elsevier; 2016:chap 65. Goldstein LB. Ischemic cerebrovascular disease. ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 407. Osgood MJ, Abularrage CJ. ...

  6. Toxic megacolon

    MedlinePlus

    ... eds. Current Surgical Therapy . 12th ed. Philadelphia, PA: Elsevier; 2017:161-164. Lichtenstein GR. Inflammatory bowel disease. ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 141. Peterson MA, Wu AW. ...

  7. Vascular dementia

    MedlinePlus

    ... Alzheimer's Disease, and Dementia . 2nd ed. Philadelphia, PA: Elsevier; 2016:chap 6. Gorelick PB, Scuteri A, Black ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 402. Peterson R, Graff-Radford ...

  8. Smear of duodenal fluid aspirate

    MedlinePlus

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. Dupont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Fritsche TR, Pritt BS. ...

  9. Hepatitis

    MedlinePlus

    ... Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 90. Pawlotsky J-M. Chronic ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 149. Sjogren MH, Bassett JT. ...

  10. Pancreatic pseudocyst

    MedlinePlus

    ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 144. Nealon WH. The management ... eds. Current Surgical Therapy . 12th ed. Philadelphia, PA: Elsevier; 2017:516-523. Tenner SC, Steinberg WM. Acute ...

  11. Leg pain

    MedlinePlus

    ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 81. Marcussen B, Hogrefe C, ... Medicine: Principles and Practice . 4th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 112. Shy ME. Peripheral neuropathies. ...

  12. Renovascular hypertension

    MedlinePlus

    ... and Rector's The Kidney . 10th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 48. Victor RG. Arterial hypertension. ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 67. Victor RG. Systemic hypertension: ...

  13. Hemolysis

    MedlinePlus

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 161. Gallagher PG. Red blood ... Basic Principles and Practice . 6th ed. Philadelphia, PA: Elsevier; 2013:chap 43. Michel M. Autoimmune and intravascular ...

  14. Small intestine aspirate and culture

    MedlinePlus

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. Dupont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Fritsche TR, Pritt BS. ...

  15. How Are Diet & Exercise Affected?

    MedlinePlus

    ... Trials Database Supporting Research Raising Awareness Our Blog Patient Education Pancreas News Basics of Pancreatic Cancer FAQs The ... Detection- Goggins Lab Sol Goldman Center Discussion Board Patient Education / Treatment and Care Overview Nutrition Post-Surgery Diet ...

  16. Is Pancreatic Cancer Hereditary?

    MedlinePlus

    ... Trials Database Supporting Research Raising Awareness Our Blog Patient Education Pancreas News Basics of Pancreatic Cancer FAQs The ... Detection- Goggins Lab Sol Goldman Center Discussion Board Patient Education / Basics of Pancreatic Cancer Is pancreatic cancer hereditary? ...

  17. What Questions Should I Ask My Doctor?

    MedlinePlus

    ... Trials Database Supporting Research Raising Awareness Our Blog Patient Education Pancreas News Basics of Pancreatic Cancer FAQs The ... Detection- Goggins Lab Sol Goldman Center Discussion Board Patient Education / Basics of Pancreatic Cancer Questions What questions should ...

  18. Metastasis

    MedlinePlus

    ... Trials Database Supporting Research Raising Awareness Our Blog Patient Education Pancreas News Basics of Pancreatic Cancer FAQs The ... Detection- Goggins Lab Sol Goldman Center Discussion Board Patient Education / Diagnosis Metastasis A major concern when diagnosing a ...

  19. Cholesterol and lifestyle

    MedlinePlus

    ... normal range. These healthy habits may help prevent future heart attacks and other health problems. Eat foods ... with health and disease. In: Goldman L, Schafer AI, eds. Goldman’s Cecil Medicine . 25th ed. Philadelphia, PA: ...

  20. Culture - colonic tissue

    MedlinePlus

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. DuPont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Hall GS, Woods GL. ...

  1. Shigellosis

    MedlinePlus

    ... Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016:chap 340. DuPont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Haines CF, Sears CL. ...

  2. Small bowel tissue smear

    MedlinePlus

    ... Management by Laboratory Method s. 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. Dupont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Fritsche TR, Pritt BS. ...

  3. Campylobacter infection

    MedlinePlus

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 303. Bhutta ZA. Acute gastroenteritis ... Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016:chap 340. DuPont HL. Approach to the ...

  4. Nasogastric feeding tube

    MedlinePlus

    ... chap 16. Ziegler TR. Malnutrition, nutritional assessment, and nutritional support in adult hospitalized patients. In: Goldman L, Schafer ... A.M. Editorial team. Related MedlinePlus Health Topics Nutritional Support Browse the Encyclopedia A.D.A.M., Inc. ...

  5. A ward without patients.

    PubMed

    1988-01-02

    Walk into Brooke ward and it doesn't feel like a ward at all. There are bright-coloured bedspreads, cuddly toys everywhere, a 1930s ball gown hangs above one of the lockers. And of course, there's Emma, the ward cat - continually fussed over by nurses and residents alike.

  6. Indigenous Knowledges and the Story of the Bean

    ERIC Educational Resources Information Center

    Brayboy, Bryan McKinley Jones; Maughn, Emma

    2009-01-01

    In this article, Bryan McKinley Jones Brayboy and Emma Maughn explore epistemic tensions within an Indigenous teacher preparation program where students question Western systems for creating, producing, reproducing, and valuing knowledge. Grounding their argument in a rich understanding of Indigenous Knowledge Systems, the authors advocate for an…

  7. Can Pedagogical Concerns Eclipse Mathematical Knowledge?

    ERIC Educational Resources Information Center

    Creager, Mark A.; Jacobson, Erik; Aydeniz, Fetiye

    2016-01-01

    Mathematical knowledge for teaching (MKT) is often thought of as a transformed, mutually-influencing mixture of content and pedagogy. However when individuals' MKT does not integrate content and pedagogy, one type of knowledge can supersede the other, sometimes unconsciously. We exemplify this with Emma, a prospective elementary teacher, whose…

  8. Contrasting nitrogen fate in watersheds using agricultural and water quality information

    USGS Publications Warehouse

    Essaid, Hedeff I.; Baker, Nancy T.; McCarthy, Kathleen A.

    2016-01-01

    Surplus nitrogen (N) estimates, principal component analysis (PCA), and end-member mixing analysis (EMMA) were used in a multisite comparison contrasting the fate of N in diverse agricultural watersheds. We applied PCA-EMMA in 10 watersheds located in Indiana, Iowa, Maryland, Nebraska, Mississippi, and Washington ranging in size from 5 to 1254 km2 with four nested watersheds. Watershed Surplus N was determined by subtracting estimates of crop uptake and volatilization from estimates of N input from atmospheric deposition, plant fixation, fertilizer, and manure for the period from 1987 to 2004. Watershed average Surplus N ranged from 11 to 52 kg N ha−1 and from 9 to 32% of N input. Solute concentrations in streams, overland runoff, tile drainage, groundwater (GW), streambeds, and the unsaturated zone were used in the PCA-EMMA procedure to identify independent components contributing to observed stream concentration variability and the end-members contributing to streamflow and NO3 load. End-members included dilute runoff, agricultural runoff, benthic-processing, tile drainage, and oxic and anoxic GW. Surplus N was larger in watersheds with more permeable soils (Washington, Nebraska, and Maryland) that allowed greater infiltration, and oxic GW was the primary source of NO3 load. Subsurface transport of NO3 in these watersheds resulted in some removal of Surplus N by denitrification. In less permeable watersheds (Iowa, Indiana, and Mississippi), NO3 was rapidly transported to the stream by tile drainage and runoff with little removal. Evidence of streambed removal of NO3 by benthic diatoms was observed in the larger watersheds.

  9. Validated Metrics of Quick Flow Improve Assessments of Streamflow Generation Processes at the Long-Term Sleepers River Research Site

    NASA Astrophysics Data System (ADS)

    Sebestyen, S. D.; Shanley, J. B.

    2015-12-01

    There are multiple approaches to quantify quick flow components of streamflow. Physical hydrograph separations of quick flow using recession analysis (RA) are objective, reproducible, and easily calculated for long-duration streamflow records (years to decades). However, this approach has rarely been validated to have a physical basis for interpretation. In contrast, isotopic hydrograph separation (IHS) and end member mixing analysis using multiple solutes (EMMA) have been used to identify flow components and flowpath routing through catchment soils. Nonetheless, these two approaches are limited by data from limited and isolated periods (hours to weeks) during which more-intensive grab samples were analyzed. These limitations oftentimes make IHS and EMMA difficult to generalize beyond brief windows of time. At the Sleepers River Research Watershed (SRRW) in northern Vermont, USA, we have data from multiple snowmelt events over a two decade period and from multiple nested catchments to assess relationships among RA, IHS, and EMMA. Quick flow separations were highly correlated among the three techniques, which shows links among metrics of quick flow, water sources, and flow path routing in a small (41 ha), forested catchment (W-9) The similarity in responses validates a physical interpretation for a particular RA approach (the Ekhardt recursive RA filter). This validation provides a new tool to estimate new water inputs and flowpath routing for more and longer periods when chemical or isotopic tracers may not have been measured. At three other SRRW catchments, we found similar strong correlations among the three techniques. Consistent responses across four catchments provide evidence to support other research at the SRRW that shows that runoff generation mechanisms are similar despite differences in catchment sizes and land covers.

  10. Chronic myeloid leukemia: reminiscences and dreams

    PubMed Central

    Mughal, Tariq I.; Radich, Jerald P.; Deininger, Michael W.; Apperley, Jane F.; Hughes, Timothy P.; Harrison, Christine J.; Gambacorti-Passerini, Carlo; Saglio, Giuseppe; Cortes, Jorge; Daley, George Q.

    2016-01-01

    With the deaths of Janet Rowley and John Goldman in December 2013, the world lost two pioneers in the field of chronic myeloid leukemia. In 1973, Janet Rowley, unraveled the cytogenetic anatomy of the Philadelphia chromosome, which subsequently led to the identification of the BCR-ABL1 fusion gene and its principal pathogenetic role in the development of chronic myeloid leukemia. This work was also of major importance to support the idea that cytogenetic changes were drivers of leukemogenesis. John Goldman originally made seminal contributions to the use of autologous and allogeneic stem cell transplantation from the late 1970s onwards. Then, in collaboration with Brian Druker, he led efforts to develop ABL1 tyrosine kinase inhibitors for the treatment of patients with chronic myeloid leukemia in the late 1990s. He also led the global efforts to develop and harmonize methodology for molecular monitoring, and was an indefatigable organizer of international conferences. These conferences brought together clinicians and scientists, and accelerated the adoption of new therapies. The abundance of praise, tributes and testimonies expressed by many serve to illustrate the indelible impressions these two passionate and affable scholars made on so many people’s lives. This tribute provides an outline of the remarkable story of chronic myeloid leukemia, and in writing it, it is clear that the historical triumph of biomedical science over this leukemia cannot be considered without appreciating the work of both Janet Rowley and John Goldman. PMID:27132280

  11. Chronic myeloid leukemia: reminiscences and dreams.

    PubMed

    Mughal, Tariq I; Radich, Jerald P; Deininger, Michael W; Apperley, Jane F; Hughes, Timothy P; Harrison, Christine J; Gambacorti-Passerini, Carlo; Saglio, Giuseppe; Cortes, Jorge; Daley, George Q

    2016-05-01

    With the deaths of Janet Rowley and John Goldman in December 2013, the world lost two pioneers in the field of chronic myeloid leukemia. In 1973, Janet Rowley, unraveled the cytogenetic anatomy of the Philadelphia chromosome, which subsequently led to the identification of the BCR-ABL1 fusion gene and its principal pathogenetic role in the development of chronic myeloid leukemia. This work was also of major importance to support the idea that cytogenetic changes were drivers of leukemogenesis. John Goldman originally made seminal contributions to the use of autologous and allogeneic stem cell transplantation from the late 1970s onwards. Then, in collaboration with Brian Druker, he led efforts to develop ABL1 tyrosine kinase inhibitors for the treatment of patients with chronic myeloid leukemia in the late 1990s. He also led the global efforts to develop and harmonize methodology for molecular monitoring, and was an indefatigable organizer of international conferences. These conferences brought together clinicians and scientists, and accelerated the adoption of new therapies. The abundance of praise, tributes and testimonies expressed by many serve to illustrate the indelible impressions these two passionate and affable scholars made on so many people's lives. This tribute provides an outline of the remarkable story of chronic myeloid leukemia, and in writing it, it is clear that the historical triumph of biomedical science over this leukemia cannot be considered without appreciating the work of both Janet Rowley and John Goldman. Copyright© Ferrata Storti Foundation.

  12. Tricuspid regurgitation

    MedlinePlus

    ... enlargement of the right side of the heart. Doppler echocardiography or right-sided cardiac catheterization may be ... Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. ... Saunders; 2016:chap 75. Nishimura. RA, Otto CM, Bownow RO, ...

  13. A rare type of Usher's syndrome.

    PubMed

    Antunica, Antonela Gverović; Kastelan, Snjezana; Bućan, Kajo; Ivanković, Mira; Radman, Maja; Karaman, Ksenija

    2013-12-01

    A case is presented of a very rare type of Usher's syndrome detected in a 30-year-old woman in her 28th week of pregnancy. She reported left eye visual impairment with a one-month history. She underwent standard ophthalmologic examination with additional procedures scheduled after childbirth, including fluorescein angiography, visual field (Goldman and Octopus) and electroretinography. Fundus examination revealed pallor of the optic disk, diffuse retinal blood vessel narrowing, no retinal pigmentation, left macular edema, vitreous liquefaction, and posterior vitreous detachment. Goldman perimetry showed narrowing of all isopters to 10 degrees, and Octopus perimetry showed peripheral decrease of retinal sensitivity. Electroretinography confirmed the diagnosis of retinitis pigmentosa sine pigmento. Upon collecting case history records, hearing disorders originating from childhood were discovered. To our knowledge, this type of retinitis in Usher's syndrome has been reported only once in the available literature.

  14. DISRUPTION IN RAT ESTROUS CYCLICITY BY THE DRINKING WATER DISINFECTANT BY-PRODUCT DIBROMOACETIC ACID: RELATIONSHIP TO A SUPPRESSION ON ESTRADIOL METABOLISM?

    EPA Science Inventory

    Disruption in Rat Estrous Cyclicity by the Drinking Water Disinfectant By-Product Dibromoacetic Acid: Relationship to A Suppression on Estradiol Metabolism?

    Ashley S. Murr and Jerome M. Goldman, Endocrinology Branch, Reproductive Toxicology Division National Health and En...

  15. Sigmund Freud's Discovery of the Etiological Significance of Childhood Sexual Traumas.

    ERIC Educational Resources Information Center

    Kuhn, Philip

    1997-01-01

    Reconstructs Freud's early treatment of Emma Eckstein so as to challenge assumptions that Freud's early writings have no place in the current discourse on child sexual abuse. Reveals how Freud first formulated the radical theory that his patients' psycho-neuroses were due to their having been sexually traumatized as children. (RJM)

  16. Treatment of Complicated Grief Using Virtual Reality: A Case Report

    ERIC Educational Resources Information Center

    Botella, C.; Osma, J.; Palacios, A. Garcia; Guillen, V.; Banos, R.

    2008-01-01

    This is the first work exploring the application of new technologies, concretely virtual reality, to facilitate emotional processing in the treatment of Complicated Grief. Our research team has designed a virtual reality environment (EMMA's World) to foster the expression and processing of emotions. In this study the authors present a description…

  17. Primary Science Interview: Science Sparks

    ERIC Educational Resources Information Center

    Bianchi, Lynne

    2016-01-01

    In this "Primary Science" interview, Lynne Bianchi talks with Emma Vanstone about "Science Sparks," which is a website full of creative, fun, and exciting science activity ideas for children of primary-school age. "Science Sparks" started with the aim of inspiring more parents to do science at home with their…

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ferris, Y.M.

    The paper by A.S. Goldman, R.R. Picard, and J.P. Shipley of Los Alamos is critiqued, particularly with respect to the following: definition of safeguards, limits of accuracy, shipper/receiver differences, statistical terminology, material balance, and errors. (DLC)

  19. NEUROENDOCRINE AND REPRODUCTIVE EFFECTS OF PESTICIDES

    EPA Science Inventory

    Neuroendocrine and Reproductive Effects of Pesticides

    1Stoker, TE, Goldman 2, JM and Cooper 2, RL.

    1Gamete and Early Embryogenesis Biology Branch and 2 Endocrinology Branch, Reproductive Toxicology Division, National Health and Environmental Effects Research Laborat...

  20. Whipple Procedure

    MedlinePlus

    ... Sol Goldman Pancreatic Cancer Research Center For Patients & Family Cancer Clinic Cyst Clinic NFPTR Medical Professionals Donate Blog Expand All Collapse All Johns Hopkins & You Our Pledge to You Choosing Johns Hopkins Importance of Experienced Surgeon Our Multidisciplinary Approach Meet Our ...

  1. Using Sites for Insights: How Historical Locations Can Help Teachers and Students with the New History GCSE

    ERIC Educational Resources Information Center

    Illingworth, Steve; Manners, Emma

    2017-01-01

    Working alongside local history teachers to prepare for the new GCSE specifications Steve Illingworth and Emma Manners were struck that many teachers were concerned about two issues in particular: the breadth and depth of knowledge demanded and new forms of assessment, especially the historic environment paper. In this article they show how both…

  2. Speedwriting--The Proven One-Year Shorthand System.

    ERIC Educational Resources Information Center

    Schindler, Irene

    Emma Dearborn originated the Speedwriting Alphabetic Shorthand in 1924. The system became well known in 1928 when it became the first shorthand system publicized for dual use in verbatim recording and selected notetaking. For the next 50 years, speedwriting was marketed in a franchise arrangement with proprietary schools. It became available to…

  3. Epistemology in Excess? A Response to Williams

    ERIC Educational Resources Information Center

    Siegei, Harvey

    2017-01-01

    Emma Williams' "In Excess of Epistemology" admirably endeavours to open the way to an account of critical thinking that goes beyond the one I have defended ad nauseum in recent decades by developing, via the work of Charles Taylor and Martin Heidegger, "a radically different conception of thinking and the human being who…

  4. Coming to see objects of knowledge: Guiding student conceptualization through teacher embodied instruction in a robotics programming class

    NASA Astrophysics Data System (ADS)

    Kwah, Helen

    This thesis explores the questions of how a teacher guides students to see concepts, and the role of gesture and gesture viewpoints in mediating the process of guidance. To examine these questions, two sociocultural theoretical frameworks--Radford's cultural-semiotic theory of knowledge objectification (e.g., 2003), and Goldman's Points of Viewing theory (e.g., 2007)--were applied to conduct a microanalytic, explanatory case study of the instructional activity of an exemplary teacher and his students in a middle school robotics programming class. According to Radford, students acquire concepts as they draw upon semiotic resources such as language and gesture to generalize and objectify initially concrete perceptions and actions. I applied Radford's framework to explain the mediations that a teacher might enact in guiding students to objectify and see concepts. Furthermore, I focused on gesture as semiotic means because of emergent research on gesture's role in communicating the visuospatial imagery that underlies math/ scientific concepts. I extended the view of gestures to the viewpoints constructed in gesture, and applied Goldman's theory to explain how perspectives might be actively constructed and shared in the process of guiding student conceptualization. Data was collected over a semester through participant observation, field notes, teacher and student interviews, and reviews of artifacts. Multimodal microanalyses were conducted on video data from eight class sessions. The findings provide confirmations and some disconfirmations about the applicability of Radford's and Goldman's theories for explaining a teacher's process of guiding student conceptualization. Notably, some of Radford's notions about de-contextualization and symbolic generalizations were not confirmed. Overall, the findings are summarized through three themes including, grounding, and perceptual organizers as two ways that gesture and other means served to both index and identify action

  5. DIBROMOACETIC ACID-INDUCED ELEVATIONS IN CIRCULATING ESTRADIOL: EFFECTS IN BOTH CYCLING AND OVARIECTOMIZED/STEROID-PRIMED FEMALE RATS

    EPA Science Inventory

    RTD-03-031
    Goldman, JM and Murr, AS. Dibromoacetic Acid-induced Elevations in Circulating Estradiol: Effects in Both Cycling and Ovariectomized/Steroid-primed Female Rats. Reproductive Toxicology (in press).

    Abstract

    Oral exposures to high concentrations of th...

  6. Lacrimal gland tumor

    MedlinePlus

    ... Abeloff's Clinical Oncology . 5th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 67. Yanoff M, Cameron JD. Diseases of the visual system. In: ... Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 423. Review ... Benign Tumors Read more Eye Cancer ...

  7. Feature Characteristics of Spontaneous Speech Production in Young Deaf Children.

    ERIC Educational Resources Information Center

    Geffner, Donna

    1980-01-01

    Sixty-five six-year-old deaf children from state supported schools were given an adaptation of the Goldman Fristoe test of articulation to assess their spontaneous speech production. Journal availability: Elsevier North Holland, Inc., 52 Vanderbilt Avenue, New York, NY 10017. (Author)

  8. HORMONAL CONTROL OF OVARIAN FUNCTION FOLLOWING CHLOROTRIAZINE EXPOSURE: EFFECT ON REPRODUCTIVE FUNCTION AND MAMMARY GLAND TUMOR DEVELOPMENT

    EPA Science Inventory

    Hormonal Control of Ovarian Function Following Chlorotriazine Exposure: Effect on Reproductive Function and Mammary Gland Tumor Development.

    Ralph L. Cooper, Susan C. Laws, Michael G. Narotsky, Jerome M. Goldman, and Tammy E. Stoker

    Abstract
    The studies review...

  9. DIBROMOACETIC ACID-INDUCED ELEVATIONS OF ESTRADIOL IN THE CYCLING AND OVARIECTOMOZED/ESTRADIOL-IMPLANTED FEMALE RAT

    EPA Science Inventory

    Goldman, JM and Murr, AS. Dibromoacetic Acid-induced Elevations of Estradiol in Both Cycling and Ovariectomized / Estradiol-implanted Female Rats

    ABSTRACT
    Haloacetic acids are one of the principal classes of disinfection by-products generated by the chlorination of mun...

  10. [Diffusion and diffusion-osmosis models of the charged macromolecule transfer in barriers of biosystems].

    PubMed

    Varakin, A I; Mazur, V V; Arkhipova, N V; Serianov, Iu V

    2009-01-01

    Mathematical models of the transfer of charged macromolecules have been constructed on the basis of the classical equations of electromigration diffusion of Helmholtz-Smolukhovskii, Goldman, and Goldman-Hodgkin-Katz. It was shown that ion transfer in placental (mimicking lipid-protein barriers) and muscle barriers occurs by different mechanisms. In placental barriers, the electromigration diffusion occurs along lipid-protein channels formed due to the conformational deformation of phospholipid and protein molecules with the coefficients of diffusion D = (2.6-3.6) x 10(-8) cm2/s. The transfer in muscle barriers is due to the migration across charged interfibrillar channels with the negative diffusion activation energy, which is explained by changes in the structure of muscle fibers and expenditures of thermal energy for the extrusion of Cl- from channel walls with the diffusion coefficient D = (6.0-10.0) x 10(-6) cm2/s.

  11. 3 CFR 8513 - Proclamation 8513 of April 30, 2010. Jewish American Heritage Month, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... America A Proclamation In 1883, the Jewish American poet Emma Lazarus composed a sonnet, entitled “The New... before America’s birth, to those of the past century who sought refuge from the horrors of pogroms and... commitment to service, faith, democracy, and peace; and of tireless work to achieve success. As leaders in...

  12. My Secondary Modern: Stories from the Invisible Generation

    ERIC Educational Resources Information Center

    Williams, Emma-Louise; Rosen, Michael

    2017-01-01

    One of the least recorded and analysed aspects of English and Welsh education is the personal experience of millions of people attending secondary modern schools following the 1944 Education Act. Since 2012, Emma-Louise Williams and Michael Rosen have hosted a moderated blog for self-selecting personal testimony from anyone involved. So far, some…

  13. Bridging the Gap--Using Social Media to Bring Together Science and Families

    ERIC Educational Resources Information Center

    Tyler, Toby; Vanstone, Emma

    2017-01-01

    In this article, first Toby Tyler describes how using Twitter to engage the community and to pursue the ICE principle (Introduce, Consolidate, and Extend) to enhance learning has brought his school community closer together. Then, Emma Vanstone highlights how schools can draw on support for engaging children with science at home by using social…

  14. Barriers to Dance Training for Young People with Disabilities

    ERIC Educational Resources Information Center

    Aujla, Imogen J.; Redding, Emma

    2013-01-01

    Dance is a viable and enjoyable activity -- and potential career -- for young people with disabilities, yet they face several barriers to participation and training. The aim of this article, by Imogen J. Aujla of the University of Bedfordshire and Emma Redding of Trinity Laban Conservatoire of Music and Dance, is to review the literature on…

  15. Earlybird in South Staffordshire: Reflections on an Innovative Model of Interagency Working to Deliver an Intervention for Families of Preschool Children with Autistic Spectrum Disorder

    ERIC Educational Resources Information Center

    Halpin, Julia; Pitt, Sally; Dodd, Emma

    2011-01-01

    In this article three education and health services professionals, Julia Halpin, Sally Pitt and Emma Dodd, describe and reflect upon the way in which a small group of professionals from health and education services worked in collaboration to meet the need to inform and empower parents of preschool children with a diagnosis of autistic spectrum…

  16. Computers on Wheels.

    ERIC Educational Resources Information Center

    Rosemead Elementary School District, CA.

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT: How does a school provide the computer learning experiences for students given the paucity of available funding for hardware, software, and staffing? Here is what one school, Emma W. Shuey in Rosemead, did after exploratory research on computers by a committee of teachers and administrators. The…

  17. Puncture Self-Healing Polymers for Aerospace Applications

    NASA Technical Reports Server (NTRS)

    Gordon, Keith L.; Penner, Ronald K.; Bogert, Phil B.; Yost, W. T.; Siochi, Emilie J.

    2011-01-01

    Space exploration launch costs on the order of $10K per pound provide ample incentive to seek innovative, cost-effective ways to reduce structural mass without sacrificing safety and reliability. Damage-tolerant structural systems can provide a route to avoiding weight penalty while enhancing vehicle safety and reliability. Self-healing polymers capable of spontaneous puncture repair show great promise to mitigate potentially catastrophic damage from events such as micrometeoroid penetration. Effective self-repair requires these materials to heal instantaneously following projectile penetration while retaining structural integrity. Poly(ethylene-co-methacrylic acid) (EMMA), also known as Surlyn is an ionomer-based copolymer that undergoes puncture reversal (self-healing) following high impact puncture at high velocities. However EMMA is not a structural engineering polymer, and will not meet the demands of aerospace applications requiring self-healing engineering materials. Current efforts to identify candidate self-healing polymer materials for structural engineering systems are reported. Rheology, high speed thermography, and high speed video for self-healing semi-crystalline and amorphous polymers will be reported.

  18. Manifestations of the MOMM Phenomenon II: Relevant Data on Professional Darwinism and Membership Composition.

    ERIC Educational Resources Information Center

    Horan, John J.; And Others

    Horan (1989) reported that graduates and employees of four institutions (Minnesota, Ohio State, Maryland, and Missouri - the "MOMM Cartel") heavily dominate every science and practice organ of the American Psychological Association's Division 17 governing body. Goldman (1990) provided additional data indicating that egregious exclusion…

  19. Mechanism and Therapy for the Shared Susceptibility to Migraine and Epilepsy after Traumatic Brain Injury

    DTIC Science & Technology

    2012-10-01

    malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury. J. Cereb. Blood Flow Metab. 31, 17–35. Leventhal, C., Rafii , S... Rafii , D., Shahar, A., Goldman, S.A., 1999. Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma

  20. Cumulative toxicity of an environmentally relevant mixture of nine regulated disinfection by-products in a multigenerational rat reproductive bioassay

    EPA Science Inventory

    CUMULATIVE TOXICITY OF AN ENVIRONMENTALLY RELEVANT MIXTURE OF NINE REGULATED DISINFECTION BY-PRODUCTS IN A MULTIGENERATIONAL RAT REPRODUCTIVE BIOASSAY J E Simmons, GR. Klinefelter, JM Goldman, AB DeAngelo, DS Best, A McDonald, LF Strader, AS Murr, JD Suarez, MH George, ES Hunte...

  1. Stimulus Picture Identification in Articulation Testing

    ERIC Educational Resources Information Center

    Mullen, Patricia A.; Whitehead, Robert L.

    1977-01-01

    Compared with 20 normal speaking and 20 articulation defective Ss (7 and 8 years old) was the percent of correct initial identification of stimulus pictures on the Goldman-Fristoe Test of Articulation with the percent correct identification on the Arizona Articulation Proficiency Scale. (Author/IM)

  2. 78 FR 23963 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ...''), Citadel Securities LLC (``Citadel''), Citigroup Financial Strategies, Inc. (``Citigroup''), Goldman, Sachs... Agreement) by the Founding Firms to NYSE Market (DE), Inc. (``NYSE Market''), an affiliate of the Exchange... the Founding Firms to NYSE Market as soon as reasonably practicable following April 2, 2013 pursuant...

  3. Bone Marrow Matters

    ERIC Educational Resources Information Center

    Dunne, Mark; Maklad, Rania; Heaney, Emma

    2014-01-01

    As a final-year student teacher specialising in primary science, Emma Heaney faced the challenge of having to plan, organise, and conduct a small-scale, classroom-based research project. She had to teach about bones in the final block practice session and thought it would be a good idea to bring in some biological specimens obtained from the local…

  4. "Three Grandes Dames" or Dayton, Ohio, as a Well-Spring of Women Special Librarians.

    ERIC Educational Resources Information Center

    Jackson, Eugene B.

    This historical consideration of the role of women librarians in three Dayton special libraries centers on three figures: (1) Caroline W. Lutz, librarian of the General Motors Research Corporation from 1922 to 1956; (2) Hope Thomas, head librarian of the United States Air Force McCook Field Library in the mid-1940's; and (3l Emma Wedenbine,…

  5. Treating Suicidal Behavior in the Mentally Retarded: The Case of Kim.

    ERIC Educational Resources Information Center

    Berman, Alan L., Ed.; And Others

    1992-01-01

    Presents case study of 36-year-old mildly retarded white woman who lived in group home and who recently tried to injure herself. Comments on the case and on interventions are given by Rowland Barrett and Anne Walters from Brown University School of Medicine, Emma Pendleton Bradley Hospital and from Howard Pressman, in independent practice in…

  6. E Complex groundbreaking

    NASA Image and Video Library

    2009-04-14

    Representatives from NASA, Orbital Sciences Corp. and Aerojet participate in a ribbon-cutting ceremony for construction of a flame deflector trench at Stennis Space Center's E Test Complex. Participants included Orbital CEO J.R. Thompson (center, left) and Stennis Space Center Director Gene Goldman (center, right).

  7. DIBROMOACETIC ACID ATTENUATES A DIMETHYLDITHIOCARBAMATE-INDUCED SUPPRESSION OF THE RAT LH SURGE

    EPA Science Inventory

    DIBROMOACETIC ACID ATTENUATES A DITHIOCARBAMATE-INDUCED SUPPRESSION OF THE LH SURGE IN THE RAT. Jerome M. Goldman, Ashley S. Murr, Angela R. Buckelew, W. Keith McElroy and Janet M. Ferrell. Repro. Toxicol. Div., NHEERL, ORD, US EPA, RTP, NC

    At elevated concentrations, the ...

  8. E Complex groundbreaking

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Representatives from NASA, Orbital Sciences Corp. and Aerojet participate in a ribbon-cutting ceremony for construction of a flame deflector trench at Stennis Space Center's E Test Complex. Participants included Orbital CEO J.R. Thompson (center, left) and Stennis Space Center Director Gene Goldman (center, right).

  9. ASSESSMENT OF TOXICANT-INDUCED ALTERATIONS IN OVARIAN STEROIDOGENESIS: A METHODOLOGICAL OVERVIEW

    EPA Science Inventory

    RTD-03-035

    Assessment of Toxicant-induced Alterations in Ovarian Steroidogenesis:
    A Methodological Overview

    Jerome M. Goldman, Susan C. Laws and Ralph L. Cooper

    Abstract

    A variety of methodological approaches have been used for the assessment of tox...

  10. Medical Device Plug-and-Play Interoperability Standards and Technology Leadership

    DTIC Science & Technology

    2014-10-01

    downloads/AboutFDA/CentersOffices/OfficeofMedicalProductsandTobacco/ CDRH /CDRHReports/UCM391521.pdf. Dr. Goldman spoke in multiple panels at this workshop...downloads/AboutFDA/CentersOffices/OfficeofMedicalProductsandTo bacco/ CDRH /CDRHReports/UCM391521.pdf  Arney D, Plourde J, Schrenker R, Mattegunta P

  11. Evidence-Based Counseling Interventions with Children of Divorce: Implications for Elementary School Counselors

    ERIC Educational Resources Information Center

    Connolly, Marianne E.; Green, Eric J.

    2009-01-01

    Parental divorce has become increasingly common for large numbers of families in schools (Lamden, King, & Goldman, 2002). This article addresses the effects of divorce on children and protective factors supporting their adjustment. Evidence-based interventions for children of divorce in elementary school counseling programs are discussed.…

  12. Plan Aggregation for Strong Cyclic Planning in Nondeterministic Domains

    DTIC Science & Technology

    2014-07-02

    Plan Aggregation for Strong Cyclic Planning in Nondeterministic Domains Ron Alforda, Ugur Kuterc, Dana Naub, Robert P. Goldmanc aASEE/NRL...addresses: ronald.alford.ctr@nrl.navy.mil (Ron Alford), ukuter@sift.net ( Ugur Kuter), nau@cs.umd.edu (Dana Nau), rpgoldman@sift.net (Robert P. Goldman

  13. FAST TRACK COMMUNICATION: Shear coordinate description of the quantized versal unfolding of a D4 singularity

    NASA Astrophysics Data System (ADS)

    Chekhov, Leonid; Mazzocco, Marta

    2010-11-01

    In this communication, by using Teichmüller theory of a sphere with four holes/orbifold points, we obtain a system of flat coordinates on the general affine cubic surface having a D4 singularity at the origin. We show that the Goldman bracket on the geodesic functions on the four-holed/orbifold sphere coincides with the Etingof-Ginzburg Poisson bracket on the affine D4 cubic. We prove that this bracket is the image under the Riemann-Hilbert map of the Poisson-Lie bracket on \\oplus _{1}^3\\mathfrak {sl}^\\ast (2,{{\\bb C}}) . We realize the action of the mapping class group by the action of the braid group on the geodesic functions. This action coincides with the procedure of analytic continuation of solutions of the sixth Painlevé equation. Finally, we produce the explicit quantization of the Goldman bracket on the geodesic functions on the four-holed/orbifold sphere and of the braid group action.

  14. Combination of geochemical and hydrobiological tracers for the analysis of runoff generating processes in a lowland catchment

    NASA Astrophysics Data System (ADS)

    Faber, Claas; Wu, Naicheng; Ulrich, Uta; Fohrer, Nicola

    2015-04-01

    Since lowlands are characterised by flat topography and low hydraulic gradients, groundwater inflow has a large influence to streamflow generation in such catchments. In catchments with intense agricultural land use, artificial drainages are often another major contributor to streamflow. They shorten the soil passage and thus change the matter retention potential as well as runoff dynamics of a catchment. Contribution of surface runoff to streamflow is usually less important in volume. However, due to high concentrations of agrochemicals, surface runoff can constitute an important entry pathway into water bodies, especially if strong precipitation events coincide with fertilizer or pesticide application. The DFG funded project "Separating surface runoff from tile drainage flow in agricultural lowland catchments based on diatoms to improve modelled runoff components and phosphorous transport" investigates prevalent processes in this context in a 50 km² lowland catchment (Kielstau, Schleswig-Holstein, Germany) with the goal of improving existing models. End Member Mixing Analysis (EMMA) is used in the project to determine the relative importance of groundwater, tile drainage and surface runoff to streamflow at daily time steps. It became apparent that geochemical tracers are suitable for distinguishing surface runoff, but are weak for the separation of tile drainage and groundwater influence. We attribute this to the strong and complex interaction between soil water and shallow groundwater tables in the catchment. Recent studies (e.g. Pfister et al. 2011, Tauro et al. 2013) show the potential of diatoms as indicators for hydrological processes. Since we found diatoms to be suitable for the separation of tile drainage and stream samples (Wu et al., unpublished data) in our catchment, we are able to include diatom derived indices (e.g. density, species moisture indices, diversity indices) as traces in EMMA. Our results show that the inclusion of diatom data in the

  15. STS-119 crew visit

    NASA Image and Video Library

    2009-05-05

    Stennis Space Center Director Gene Goldman (r to l) presents a commemorative photo of a space shuttle main engine test firing to STS-119 Mission Commander Lee Archambault, Pilot Tony Antonelli and Mission Specialists Steve Swanson and Richard Arnold during the crew's May 5 visit to the facility.

  16. Becoming Literate in English as a Second Language.

    ERIC Educational Resources Information Center

    Goldman, Susan R., Ed.; Trueba, Henry T., Ed.

    A collection of articles on English-as-a-Second-Language literacy and literacy education include: "Contextual Issues in the Study of Second Language Literacy" (Susan R. Goldman); "Mexican Adult Literacy: New Directions for Immigrants" (Concha Delgado-Gaitan); "Factors Affecting Development of Second Language Literacy" (Richard Duran); "Reading in…

  17. A Research Program in Computer Technology

    DTIC Science & Technology

    1975-09-01

    Dale M. Chase Neil M. Goldman Jeannette Christen~sen Norton R. Green feld Kathie Cole grove John F. Heafner Nancy Dechter James Koda Oralio E. Garza...Thomas L. Boynton Stephen L. Casner E. Randolph Cole James Koda Robert Parker Paul Raveling Dono Van-Mierop Research Assistant: John K. Kastner

  18. Coordination of BRCA1/BARD1- and MRE11/RAD50/NBS1-dependent DNA Transactions in Breast Tumor Suppression

    DTIC Science & Technology

    2011-07-01

    prevent toxic chromosome rearrangements. Because MMEJ is active throughout the cell cycle, it could pro- mote translocations when any of the following...in preserving genomic stability. Genes Dev. 24:1680–94 66. Keelagher RE, Cotton VE, Goldman AS, Borts RH. 2011. Separable roles for exonuclease I in

  19. Coordination of BRCA1/BARD1- and MRE11/RAD50/NBS1-Dependent DNA Transactions in Breast Tumor Suppression

    DTIC Science & Technology

    2011-07-01

    active throughout the cell cycle, it could pro- mote translocations when any of the following aberrancies occur: (a) inhibition of C-NHEJ; (b...in preserving genomic stability. Genes Dev. 24:1680–94 66. Keelagher RE, Cotton VE, Goldman AS, Borts RH. 2011. Separable roles for exonuclease I in

  20. EFFECTS OF 20 WEEK EXPOSURES IN FEMALE SPRAGUE-DAWLEY (S-D) RATS TO DIBROMOACETIC ACID, A DRINKING WATER DISINFECTANT BY-PRODUCT

    EPA Science Inventory

    Effects of 20 week exposures in female Sprague-Dawley (S-D) rats to the drinking water disinfection by-product dibromoacetic acid. A S Murr and J M Goldman, Endocrinol. Br., RTD, NHEERL, ORD, US EPA, Res. Tri. Pk, NC. Sponsor: Audrey Cummings

    The drinking water disinfect...

  1. EFFECTS OF 20 WEEK EXPOSURES IN FEMALE SPRAGUE-DAWLEY (S-D) RATS TO THE DRINKING WATER DISINFECTION BY-PRODUCT DIBROMOACETIC ACID

    EPA Science Inventory

    Effects of 20 week exposures in female Sprague-Dawley (S-D) rats to the drinking water disinfection by-product dibromoacetic acid. A S Murr and J M Goldman, Endocrinol. Br., RTD, NHEERL, ORD, US EPA, Res. Tri. Pk, NC. Sponsor: Audrey Cummings

    The drinking water disinfect...

  2. 2018 USA Science and Engineering Festival

    NASA Image and Video Library

    2018-04-06

    Emma Marcucci, Education and Outreach Scientist at the Space Telescope Science Institute, speaks about the planets in our Solar System during Sneak Peek Friday at the USA Science and Engineering Festival, Friday, April 6, 2018 at the Walter E. Washington Convention Center in Washington, DC. The festival is open to the public April 7-8. Photo Credit: (NASA/Joel Kowsky)

  3. Communications Processors: Categories, Applications, and Trends

    DTIC Science & Technology

    1976-03-01

    allow switching from BSC to SDLC .(12) Standard protocols would ease the requirement that communications processor software convert from one...COMMANDER c^/g^_ (^-»M-^ V »*-^ FRANK J. EMMA, Colonel, USAF Director, information Systems Technology Applications Office Deputy for Command...guidelines in selecting a device for a specific application are included, with manufacturer models presented as illustrations. UNCLASSIFIED SECURITY

  4. Correction to Dittmar, Halliwell, and Ive (2006)

    ERIC Educational Resources Information Center

    Dittmar, Helga; Halliwell, Emma; Ive, Suzanne

    2006-01-01

    Reports an error in "Does Barbie make girls want to be thin? The effect of experimental exposure to images of dolls on the body image of 5- to 8-year-old girls" by Helga Dittmar, Emma Halliwell and Suzanne Ive ("Developmental Psychology," 2006 Mar, Vol 42[2], 283-292). A substantive error occurs in the Body shape dissatisfaction section on page…

  5. Expanding Applications of SERS through Versatile Nanomaterials Engineering (Postprint)

    DTIC Science & Technology

    2017-06-22

    AFRL-RX-WP-JA-2017-0341 EXPANDING APPLICATIONS OF SERS THROUGH VERSATILE NANOMATERIALS ENGINEERING (POSTPRINT) M. Fernanda...AND SUBTITLE EXPANDING APPLICATIONS OF SERS THROUGH VERSATILE NANOMATERIALS ENGINEERING (POSTPRINT) 5a. CONTRACT NUMBER FA8650-15-2-5518 5b...Expanding applications of SERS through versatile nanomaterials engineering M. Fernanda Cardinal, Emma Vander Ende, Ryan A. Hackler, Michael O. McAnally

  6. TESOL Newsletter, Volume XIV, Numbers 1-6.

    ERIC Educational Resources Information Center

    Haskell, John F., Ed.

    1980-01-01

    Six 1980 issues of the TESOL Newsletter are presented. Topics include the following: preparing a written paper for oral presentation (Fraida Dubin); current trends in teaching English as a second language (TESL) (Ruth Crymes); ESL syllabuses (Carlos Yorio); teaching Black English (Lorraine Goldman); the state of certification and employment within…

  7. 76 FR 71092 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... quoted prices in the respective SPX series at the time of execution, each constituent execution will be... Demeterfi, Emanuel Derman, Michael Kamal and Joseph Zou, Goldman Sachs Quantitative Strategies Research... series. The following table shows the SPX option mid-quote prices prevailing at the time of the S&P 500...

  8. 50th Annual Fuze Conference. Session 1 and 2

    DTIC Science & Technology

    2006-05-11

    PROGRAM OFFICE AMSRD-AAR-AIJ J. Goldman X6060 STRATEGIC MGT OFFICE AMSRD-AAR-EMS D. Denery X6081 KNOWLEDGE MANAGEMENT OFFICE AMSRD-AAR-EMK G. Albinson...Tail-Mounted Configuration (MK-82 Demo) UHF to L-Band Pulse Doppler Radar Using Low Cost COTS Components Nose and Tail Mount Configurations Only

  9. Dealing with Multiple Documents on the WWW: The Role of Metacognition in the Formation of Documents Models

    ERIC Educational Resources Information Center

    Stadtler, Marc; Bromme, Rainer

    2007-01-01

    Drawing on the theory of documents representation (Perfetti et al., Toward a theory of documents representation. In: H. v. Oostendorp & S. R. Goldman (Eds.), "The construction of mental representations during reading." Mahwah, NJ: Erlbaum, 1999), we argue that successfully dealing with multiple documents on the World Wide Web requires readers to…

  10. Coming to See Objects of Knowledge: Guiding Student Conceptualization through Teacher Embodied Instruction in a Robotics Programming Class

    ERIC Educational Resources Information Center

    Kwah, Helen

    2013-01-01

    This thesis explores the questions of how a teacher guides students to see concepts, and the role of gesture and gesture viewpoints in mediating the process of guidance. To examine these questions, two sociocultural theoretical frameworks--Radford's cultural-semiotic theory of knowledge objectification (e.g., 2003), and Goldman's Points of Viewing…

  11. Keeping the Faith: How Moving from School to Afterschool Kept Me an Educator

    ERIC Educational Resources Information Center

    Rabinoff-Goldman, Lily

    2007-01-01

    Following a difficult two year teaching commitment with Teach for America as a sixth-grade teacher in the Bronx, Lily Rabinoff-Goldman joined the staff of an effective, child-centered after-school program. Ex-teachers and after-school programming have a mutually beneficial relationship. Schoolteachers know how to build curriculum, discipline…

  12. Emma Lucy Braun's forest plots in eastern North America.

    PubMed

    Ricklefs, Robert E

    2018-02-01

    Relative abundances of tree species are presented for the 348 forest plots described in E. Lucy Braun's (1950) book, Deciduous Forests of Eastern North America (Hafner, New York, facsimile reprint 1972). Information about the plots includes forest type, location with latitude and longitude, WorldClim climate variables, and sources of original studies where applicable. No copyright restrictions are associated with the use of this data set. Please cite this article when the data are used in other publications. © 2017 by the Ecological Society of America.

  13. Identifying with "Emma": Some Problems for the Feminist Reader.

    ERIC Educational Resources Information Center

    Moffat, Wendy

    1991-01-01

    Explores questions about the use of history in teaching literature and about the relation between academic reading (with its emphasis on form and the objectification of the reading process) and naive reading (which depends on a psychological identification with a character). Illustrates these issues through a discussion of a feminist reader's…

  14. NASA Day of Remembrance

    NASA Image and Video Library

    2009-01-29

    Stennis Space Center Director Gene Goldman (left) and Deputy Director Patrick Scheuermann place a wreath in StenniSphere in memory of the 17 astronauts lost in service of the space program since 1967. The wreath was placed during NASA's 2009 Day of Remembrance, observed each year on the last Thursday of January.

  15. EFFECTS OF BROMODICHLOROMETHANE (BDCM) ON EX VIVO LUTEAL FUNCTION IN THE F344 RAT DURING PREGNANCY

    EPA Science Inventory

    Effects of Bromodichloromethane (BDCM) on Ex Vivo Luteal Function In the Pregnant F344 Rat

    Susan R. Bielmeier1, Ashley S. Murr2, Deborah S. Best2, Jerome M. Goldman2, and Michael G. Narotsky2

    1Curriculum in Toxicology, Univ. of North Carolina, Chapel Hill, NC 27599,...

  16. Yes! I Am a Researcher. The Research Story of a Young Adult with Down Syndrome

    ERIC Educational Resources Information Center

    White, Emma L.; Morgan, Michelle F.

    2012-01-01

    My name is Emma I am 28 years old and I have Down syndrome. This is an article about my story about becoming a researcher. This article has lots of photographs of me doing research. It has information about the things I did with research. It has examples of some of my research work. This article lets me share my story with other people. This…

  17. kwayask e-ki-pe-kiskinowapahtihicik = Their Example Showed Me the Way: A Cree Woman's Life Shaped by Two Cultures.

    ERIC Educational Resources Information Center

    Minde, Emma; Ahenakew, Freda, Ed.; Wolfart, H. C., Ed.

    Emma Minde (nee Memnook)was born in 1907 in Saddle Lake, Alberta. In 1927 she was given by her father in an arranged marriage to Joe Minde, who lived in Hobbema, Alberta. In this recorded autobiography taped in 1988 when she was 81 years old, little is said about her parents and her life as a child other than that she spent 7 years at a…

  18. Hydrochemical assessment of freshening saline groundwater using multiple end-members mixing modeling: A study of Red River delta aquifer, Vietnam

    NASA Astrophysics Data System (ADS)

    Kim, Ji-Hyun; Kim, Kyoung-Ho; Thao, Nguyen Thi; Batsaikhan, Bayartungalag; Yun, Seong-Taek

    2017-06-01

    In this study, we evaluated the water quality status (especially, salinity problems) and hydrogeochemical processes of an alluvial aquifer in a floodplain of the Red River delta, Vietnam, based on the hydrochemical and isotopic data of groundwater samples (n = 23) from the Kien Xuong district of the Thai Binh province. Following the historical inundation by paleo-seawater during coastal progradation, the aquifer has been undergone progressive freshening and land reclamation to enable settlements and farming. The hydrochemical data of water samples showed a broad hydrochemical change, from Na-Cl through Na-HCO3 to Ca-HCO3 types, suggesting that groundwater was overall evolved through the freshening process accompanying cation exchange. The principal component analysis (PCA) of the hydrochemical data indicates the occurrence of three major hydrogeochemical processes occurring in an aquifer, namely: 1) progressive freshening of remaining paleo-seawater, 2) water-rock interaction (i.e., dissolution of silicates), and 3) redox process including sulfate reduction, as indicated by heavy sulfur and oxygen isotope compositions of sulfate. To quantitatively assess the hydrogeochemical processes, the end-member mixing analysis (EMMA) and the forward mixing modeling using PHREEQC code were conducted. The EMMA results show that the hydrochemical model with the two-dimensional mixing space composed of PC 1 and PC 2 best explains the mixing in the study area; therefore, we consider that the groundwater chemistry mainly evolved by mixing among three end-members (i.e., paleo-seawater, infiltrating rain, and the K-rich groundwater). The distinct depletion of sulfate in groundwater, likely due to bacterial sulfate reduction, can also be explained by EMMA. The evaluation of mass balances using geochemical modeling supports the explanation that the freshening process accompanying direct cation exchange occurs through mixing among three end-members involving the K-rich groundwater. This

  19. Lack of utility of telemetry monitoring for identification of cardiac death and life-threatening ventricular dysrhythmias in low-risk patients with chest pain.

    PubMed

    Hollander, Judd E; Sites, Frank D; Pollack, Charles V; Shofer, Frances S

    2004-01-01

    Low-risk patients with chest pain are often admitted to monitored beds; however, the use of telemetry beds in this cohort is not evidence based. We tested the hypothesis that monitoring admitted low-risk patients with chest pain for dysrhythmia is low yield (<1% detection of life-threatening dysrhythmias requiring treatment). We conducted a prospective cohort study of emergency department (ED) patients with chest pain with a Goldman risk score of less than 8%, a normal initial creatine kinase-MB level, and a negative initial troponin I level admitted to non-ICU monitored beds. Investigators followed the hospital course daily. The main outcome was cardiovascular death and life-threatening ventricular dysrhythmia during telemetry. Of 3,681 patients with chest pain who presented to the ED, 1,750 patients were admitted to non-ICU monitored beds. Of these, 1,029 patients had a Goldman risk score of less than 8%, a troponin I level of less than 0.3 ng/mL, and a creatine kinase-MB level of less than 5 ng/mL (accounting for 59% of all chest pain telemetry admissions). During hospitalization, there were no patients with sustained ventricular tachycardia/ventricular fibrillation requiring treatment on the telemetry service (0%; 95% confidence interval [CI] 0% to 0.3%). There were 2 deaths: neither was cardiovascular in nature or preventable by monitoring (cardiovascular preventable death rate=0%; 95% CI 0.0% to 0.3%). The routine use of telemetry monitoring for low-risk patients with chest pain is of limited utility. Admission to nonmonitored beds might help alleviate ED crowding without increasing risk of adverse events caused by dysrhythmia in patients with a Goldman risk of less than 8%, an initial troponin I level of less than 0.3 ng/mL, and a creatine kinase-MB level of less than 5 ng/mL.

  20. STS-124 crew visits Stennis

    NASA Image and Video Library

    2008-07-23

    NASA's John C. Stennis Space Center Deputy Director Gene Goldman (center) welcomed members of the STS-124 Discovery space shuttle crew during their July 23 visit to the center. Crew members who visited Stennis were (l to r) Pilot Ken Ham, Mission Specialist Karen Nyberg, Kelly, and Mission Specialists Ron Garan and Mike Fossum.

  1. 78 FR 42436 - Procedures To Establish Appropriate Minimum Block Sizes for Large Notional Off-Facility Swaps and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-16

    ... (ICE). Gold (COMEX and NYSE Liffe).. 2,500 troy oz. Goldman Sachs Commodity Index 5,000 times dollars... (NYMEX) 1,000 troy oz. PG&E Citygate Basis (ICE and 62,500 MMBtu. NYMEX). PJM Western Hub Real Time Off...). Platinum (NYMEX) 500 troy oz. Rainfall Index (CME)......... 10,000 times dollars. index. Rough Rice (CBOT...

  2. Patterns of Auditory Perception Skills in Children with Learning Disabilities: A Computer-Assisted Approach.

    ERIC Educational Resources Information Center

    Pressman, E.; And Others

    1986-01-01

    The auditory receptive language skills of 40 learning disabled (LD) and 40 non-disabled boys (all 7 - 11 years old) were assessed via computerized versions of subtests of the Goldman-Fristoe-Woodcock Auditory Skills Test Battery. The computerized assessment correctly identified 92.5% of the LD group and 65% of the normal control children. (DB)

  3. Knowledge, Belief, and Science Education: A Contribution from the Epistemology of Testimony

    ERIC Educational Resources Information Center

    Ferreira, Tiago Alfredo S.; El-Hani, Charbel N.; da Silva-Filho, Waldomiro José

    2016-01-01

    This article intends to show that the defense of "understanding" as one of the major goals of science education can be grounded on an anti-reductionist perspective on testimony as a source of knowledge. To do so, we critically revisit the discussion between Harvey Siegel and Alvin Goldman about the goals of science education, especially…

  4. Hancock County Awards Gala

    NASA Image and Video Library

    2008-08-26

    Gene Goldman (left), deputy director of NASA's John C. Stennis Space Center, accepts an Award of Excellence from Jack Zink, executive director of the Hancock County Port and Harbor Commission, during the 2008 Annual Hancock County Awards Gala. The Award of Excellence was presented to recognize Stennis Space Center's contribution to NASA's 50 years of excellence in space exploration.

  5. Medical Device Plug-and-Play Interoperability Standards and Technology Leadership

    DTIC Science & Technology

    2015-10-01

    implemented connectivity to an EHR as an HL7 FHIR gateway from OpenICE. The monitor we used can measure heart rate from EKG, from the pulse oximeter , or... Pulse 2014:5(6):37-39. 2. Wu PL, Raguraman D, Sha L, Berlin RB, Goldman JM. WiP abstract: A treatment coordination protocol for cyber-physical-human

  6. Adolescent Literacy: Learning and Understanding Content

    ERIC Educational Resources Information Center

    Goldman, Susan R.

    2012-01-01

    Learning to read--amazing as it is to small children and their parents--is one thing. Reading to learn, explains Susan Goldman of the University of Illinois at Chicago, is quite another. Are today's students able to use reading and writing to acquire knowledge, solve problems, and make decisions in academic, personal, and professional arenas? Do…

  7. EFFECTS OF BROMODICHLOROMETHANE (BDCM) ON EX VIVO LUTEAL FUNCTION IN THE PREGNANT F344 RAT

    EPA Science Inventory

    EFFECTS OF BROMODICHLOROMETHANE (BDCM) ON EX VIVO LUTEAL FUNCTION IN THE PREGNANT F344 RAT.

    S. R. Bielmeier1, A. S. Murr2, D. S. Best2, J. M. Goldman2, and M. G. Narotsky2

    1 Curriculum in Toxicology, Univ. of North Carolina, Chapel Hill, NC, USA
    2 Reproductive T...

  8. EFFECTS OF BROMODICHLOROMETHANE (BDCM) ON EX VIVO LUTEAL FUNCTION IN THE F344 RAT

    EPA Science Inventory

    EFFECTS OF BROMODICHLOROMETHANE (BDCM) ON EX VIVO LUTEAL FUNCTION IN THE PREGNANT F344 RAT.

    S. R. Bielmeier1, A. S. Murr2, D. S. Best2, J. M. Goldman2, and M. G. Narotsky2

    1 Curriculum in Toxicology, Univ. of North Carolina, Chapel Hill, NC, USA
    2 Reproductive T...

  9. Employee Attitudes within the Federal Aviation Administration

    DTIC Science & Technology

    2004-12-01

    program to remain credible, employees must see a link between their feedback and action planning. As an example, subordinates rated supervisors who... Assistance Program ?-------------------------------------------------------------------------------------------- 10. Overall, how satisfied are you with... Employee Attitudes Within the Federal Aviation Administration Carla A. Hackworth1 Crystal E. Cruz1 Scott Goldman1 Dan G. Jack2 S. Janine King2

  10. Community Youth Engagement in East Palo Alto: A Study of the Youth Arts and Music Center Initiative

    ERIC Educational Resources Information Center

    Henderson, Jamila; Biscocho, Francine; Gerstein, Amy

    2016-01-01

    The Youth Arts and Music Center Initiative is a community-wide effort to design and build an arts center in East Palo Alto. The six-year process, supported by the Goldman Foundation, centered on youth leadership and the arts, and engaged a cross-sector collaborative of partner organizations in an attempt to address the city's shortage of existing…

  11. Making Connections through the Lens of Blue Man Group

    ERIC Educational Resources Information Center

    Stephens, Pam

    2005-01-01

    The Blue Man Group began in 1988 when friends Matt Goldman, Phil Stanton, and Chris Wink all living in New York--voiced their increasing disgruntlement and boredom with urban life. With a gut feeling that creativity and a tribal-like community could prosper in their metropolitan environment, the friends decided to confront the issues rather than…

  12. Environmental Affective Dispositions Scale (EADS): The Study of Validity and Reliability and Adaptation to Turkish

    ERIC Educational Resources Information Center

    Fettahlioglu, Pinar; Timur, Serkan; Timur, Betül

    2016-01-01

    The aim of this study is to conduct a research under circumstances of Turkey about the validity and reliability of the Affective Tendencies towards Environmental Scale prepared by Yavetz, Goldman and Pe'er (2009). The translation of this scale to Turkish was done by the researchers and language specialists. And then, the scale was evaluated by the…

  13. Promotion Opportunities of Minorities to the Controlled Grades in the Navy Nurse Corps

    DTIC Science & Technology

    1992-12-01

    and Smith, in their book Modern Labor Economics (1991), note two types of wage differential with different sources and, therefore, potentially...Role Strain," Health Services Research, Vol. 24, No. 5, December, 1989, p. 693-707. Ehrenberg, Ronald G., and Smith, Robert S., Modern Labor ... Economics : Theory and Public Policy, Fourth Edition, HarperCollins Publishers, New York, 1991. Felder, Emma, and Riesch, Susan, "The Status of Minority Nurses

  14. Empowering Prospective Teachers to Become Active Sense-Makers: Multimodal Modeling of the Seasons

    NASA Astrophysics Data System (ADS)

    Kim, Mi Song

    2015-10-01

    Situating science concepts in concrete and authentic contexts, using information and communications technologies, including multimodal modeling tools, is important for promoting the development of higher-order thinking skills in learners. However, teachers often struggle to integrate emergent multimodal models into a technology-rich informal learning environment. Our design-based research co-designs and develops engaging, immersive, and interactive informal learning activities called "Embodied Modeling-Mediated Activities" (EMMA) to support not only Singaporean learners' deep learning of astronomy but also the capacity of teachers. As part of the research on EMMA, this case study describes two prospective teachers' co-design processes involving multimodal models for teaching and learning the concept of the seasons in a technology-rich informal learning setting. Our study uncovers four prominent themes emerging from our data concerning the contextualized nature of learning and teaching involving multimodal models in informal learning contexts: (1) promoting communication and emerging questions, (2) offering affordances through limitations, (3) explaining one concept involving multiple concepts, and (4) integrating teaching and learning experiences. This study has an implication for the development of a pedagogical framework for teaching and learning in technology-enhanced learning environments—that is empowering teachers to become active sense-makers using multimodal models.

  15. [Can the degree of renal artery stenosis be automatically quantified?].

    PubMed

    Cherrak, I; Jaulent, M C; Azizi, M; Plouin, P F; Degoulet, P; Chatellier, G

    2000-08-01

    The objective of the reported study is to validate a computer system, QUASAR, dedicated to the quantification of renal artery stenoses. This system estimates automatically the reference diameter and calculates the minimum diameter to compute a degree of stenosis. A hundred and eighty images of atheromatous stenoses between 10% and 80% were collected from two French independent protocols. For the 49 images of the EMMA protocol, the results from QUASAR were compared with the visual estimation of an initial investigator and with the results from a reference method based on a panel of fixe experienced experts. For the 131 images of the ASTARTE protocol, the results from QUASAR were compared with those from a semi-automatic quantification system and with those from a system based on densitometric analysis. The present work validates QUASAR in a population of narrow atheromatous stenoses (> 50%). In the context of the EMMA protocol, QUASAR is not significantly different from the mean of the fixe experts. It is unbiased and more precise than the estimation of a single investigator. In the context of the ASTARTE protocol, there is no significant difference between the three methods for the stenoses higher than 50%, however, globally, QUASAR surestimates significantly (up to 10%) the degree of stenosis.

  16. Tracking the evolution of stream DOM source during storm events using end member mixing analysis based on DOM quality

    NASA Astrophysics Data System (ADS)

    Yang, Liyang; Chang, Soon-Woong; Shin, Hyun-Sang; Hur, Jin

    2015-04-01

    The source of river dissolved organic matter (DOM) during storm events has not been well constrained, which is critical in determining the quality and reactivity of DOM. This study assessed temporal changes in the contributions of four end members (weeds, leaf litter, soil, and groundwater), which exist in a small forested watershed (the Ehwa Brook, South Korea), to the stream DOM during two storm events, using end member mixing analysis (EMMA) based on spectroscopic properties of DOM. The instantaneous export fluxes of dissolved organic carbon (DOC), chromophoric DOM (CDOM), and fluorescent components were all enhanced during peak flows. The DOC concentration increased with the flow rate, while CDOM and humic-like fluorescent components were diluted around the peak flows. Leaf litter was dominant for the DOM source in event 2 with a higher rainfall, although there were temporal variations in the contributions of the four end members to the stream DOM for both events. The contribution of leaf litter peaked while that of deeper soils decreased to minima at peak flows. Our results demonstrated that EMMA based on DOM properties could be used to trace the DOM source, which is of fundamental importance for understanding the factors responsible for river DOM dynamics during storm events.

  17. 2005 International Infantry and Joint Services Small Arms Systems Annual Symposium Exhibition and Firing Demonstration

    DTIC Science & Technology

    2005-05-19

    Noon Awards Luncheon Chinn Award Presentation Mr. Richard Audette, Chinn Award Recipient, 2005 Presented by Mr. Joel Goldman Hathcock ...Award Presentation Mr. Christopher P. Mitternight, Hathcock Award Recipient, 2005 Presented by Mr. Charles Buxton 1:30 - 5 PM Concurrent Sessions...Schedule) 1Q/FY08 POC: James Hahn / 973-724-2117 PM: Chris Grassano / 973-724-5246 Technology Supercapacitor based power

  18. Detecting Human Activity Using Acoustic, Seismic, Accelerometer, Video, and E-field Sensors

    DTIC Science & Technology

    2011-09-01

    Detecting Human Activity using Acoustic, Seismic, Accelerometer, Video, and E-field Sensors by Sarah H. Walker and Geoffrey H. Goldman...Adelphi, MD 20783-1197 ARL-TR-5729 September 2011 Detecting Human Activity using Acoustic, Seismic, Accelerometer, Video, and E-field Sensors...DD-MM-YYYY) September 2011 2. REPORT TYPE 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Detecting Human Activity using Acoustic

  19. Turbulence in molecular clouds - A new diagnostic tool to probe their origin

    NASA Technical Reports Server (NTRS)

    Canuto, V. M.; Battaglia, A.

    1985-01-01

    A method is presented to uncover the instability responsible for the type of turbulence observed in molecular clouds and the value of the physical parameters of the 'placental medium' from which turbulence originated. The method utilizes the observational relation between velocities and sizes of molecular clouds, together with a recent model for large-scale turbulence (constructed by Canuto and Goldman, 1985).

  20. The Search for Small Businesses with Investments in Metric Production.

    DTIC Science & Technology

    1981-06-02

    the Small Business Administration (SBA), Charles Thiel of the Federal Emergency Management Agency (FEMA), David Goldman of the National Bureau of...among America’s manufacturers. This policy has engendered little cost and few problems for the nation’s small businesses . They are managing quite... Management Association Small Business Administration, Towson. Md. Scientific Apparatus Makers Association American National Standards Institute

  1. Physiological Sociology. Endocrine Correlates of Status Behaviors,

    DTIC Science & Technology

    1975-01-01

    affiliative bonding. One psychiatric illness which manifests itself in social structural relationships in a profound was is sociopathic behavior. By the...very nature of the sociopathic individual, persons with the disorder display altered social behavior (Robins, 1966). The question as to whether such...Oxford: Oxford University Press, 1971. Goldman, H., Lindner, L., Dinitz, S., and Allen, H. The simple sociopath : Physiologic and sociologic

  2. Academic Text Features and Reading in English as a Second Language

    DTIC Science & Technology

    1989-08-29

    students rely on a number of compensatory reading strategies. Commonly cited strategies include reading assisted by an English dictionary , asking peers for...Armbruster (1985), while concerned with monolingual students, offer informative suggestions that can be extended to breach this gap. They outline...attention to text information is positively affected by signaling devices among monolingual subjects. Goldman (1988) has reported that ESL college stujoi

  3. Recasting NATO’s Strategic Concept. Possible Directions for the United States

    DTIC Science & Technology

    2009-01-01

    the end of the Cold War, these missions have proven more and more challenging for the alliance as their distance from Brus - sels increases. Meanwhile...www.basicint.org/europe/NATO/afghanistan.pdf Sherwood-Randall, Elizabeth , Alliances and American National Security, Strategic Studies Institute, U.S. Army War...Huffington Post, April 1, 2008. As of July 14, 2009: http://www.huffingtonpost.com/ elizabeth -sherwoodrandall/is-nato-dead-or alive_b_94469.html Sky, Emma

  4. State of STEM (SoSTEM) Address

    NASA Image and Video Library

    2014-01-29

    Montgomery Blair High School Student Newspaper “Silver Chips” Online Editor-in-Chief Aanchal Johri, right, and Photo Editor Emma Howells, left, from Silver Spring, MD. interview NASA Astronaut Joe Acaba at the annual White House State of Science, Technology, Engineering, and Math (SoSTEM) address, Wednesday, Jan. 29, 2014, in the South Court Auditorium in the Eisenhower Executive Office Building on the White House complex in Washington. Photo Credit: (NASA/Bill Ingalls)

  5. Inference of personality projected onto fictional characters having an author's first name.

    PubMed

    Barry, H

    2001-12-01

    Jane Austen projected some of her personality characteristics onto her fictional namesakes Jane Bennet in the novel Pride and Prejudice and Jane Fairfax in the novel Emma. Wishful fantasy seems satisfied by two attributes of both Janes. They are very beautiful, and they marry rich men they love. A feeling of inferiority was expressed by two attributes of both Janes, depicted as deficient in social communication and subordinate to the heroine of the novel.

  6. Emma: Art Therapy Illustrating Personal and Universal Images of Loss.

    ERIC Educational Resources Information Center

    Mango, Christina

    1992-01-01

    Art work produced by geriatric patient on psychiatric ward illustrated metaphors of loss. After three months, patient was diagnosed with liver cancer; she died three weeks later. All work was produced before cancer diagnosis, yet it showed similarities to work by cancer patients, suggesting that client unconsciously knew she was dying and worked…

  7. The impact of antemortem computed tomographic scanning on postmortem examination rate and frequency of missed diagnosis: A retrospective analysis of postmortem examination data.

    PubMed

    Liisanantti, Janne Henrik; Ala-Kokko, Tero Ilmari

    2015-12-01

    The present study was conducted to explore the impact of computed tomographic (CT) scanning on the diagnostic discrepancy rate. This single-center, retrospective study reviewed postmortem examination results, clinical diagnoses, and radiologic imaging data for patients admitted to the intensive care unit (ICU) in 2008 to 2013. The Goldman criteria were used to classify diagnostic discrepancies. The data of 577 patients who died during their ICU stay were retrieved. The postmortem examination rate was 42.9% (n=248). Significant diagnostic discrepancies (Goldman I and II) were recorded in 24 cases (9.7%). The postmortem examination rate decreased significantly from the first half (n=143; 51.1%) to the second half (n=105; 35.4%) of the study period (P<.0001). Among those with postmortem examinations, the use of antemortem body CT scans increased significantly from the first half (n=59; 41.3%) to the second half (n=64; 51.0%; P=.002) of the study period. The significant diagnostic discrepancy rate did not change with time (8.4% vs 11.4%, respectively; P=.424). The postmortem examination rate has decreased, whereas antemortem CT scans has increased. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Morphological and molecular genetic diversity of Strongyluris calotis (Nematoda: Ascaridida: Heterakidae) in South East and East Asian lizards.

    PubMed

    Tran, Binh Thi; Ong, An Vinh; Luc, Pham Van; Sato, Hiroshi

    2016-07-01

    Strongyluris calotis is a heterakid nematode in the large intestine of agamid lizards (Reptilia: Sauria: Agamidae) from the Oriental Region. The standard light microscopic definition of the species counts the "caudal papillae" as 10 pairs on male worms. However, previous work from our group using scanning electron microscopy (SEM) on the heterakid from agamid lizards in Japan, Taiwan, and Singapore revealed that this counting contained a pair of phasmids and that two pairs of postcloacal papillae were completely fused to form a pair of united papillae, thus resulting in "10 pairs." In the present study, we examined S. calotis specimens from the Emma Gray's forest lizard, Calotes emma (Agamidae), living in the plain forest at low altitude, and the Vietnam false bloodsucker, Pseudocalotes brevipes (Agamidae), living in the mountainous forest at high altitude in the northern part of Vietnam. Using SEM, the arrangement of caudal papillae in male worms from an Emma Gray's forest lizard was found to be comparable to classical S. calotis specimens from agamid lizards collected in Japan, Taiwan, and Singapore. However, male worms from Vietnam false bloodsuckers did not have a pair of united papillae but had 10 pairs of independent caudal papillae with a pair of phasmids. Molecular genetic analyses of the ribosomal RNA gene (rDNA) of worms of the classical S. calotis morphotype from Japan and Singapore and two S. calotis morphotypes from Vietnam demonstrated absolutely identical nucleotide sequences of partial 18S rDNA (at least 1764 base pairs (bp)) and 5.8S rDNA (158 bp). However, intraspecific differences were detected in other regions of the rDNA, related to the geographical distribution of hosts regardless of morphotype: 97.8-98.5 % identity (443-446 bp/453 bp) in the internal transcribed spacer (ITS)-1 region, 96.6-98.0 % identity (425-431 bp/440 bp) in the ITS-2 region, and 99.6-99.7 % identity (1149-1151 bp/1154 bp) in the 28S rDNA. Thus, in the future, taxonomic

  9. Ventilatory Responses to Exercise While Eliciting the Relaxation Response,

    DTIC Science & Technology

    1982-04-16

    Kent B. Pandolf, Bruce Cadarette, Leslie Levine, Ralph F. Goldman, and Herbert Benson. From the Division of Behavioral Medicine, Department of...been observed with the elicitation of the relaxation response at rest differ from those that occur during sleep or hypnosis (14). The relaxation response...alterations which were observed in our experimental group during the intervention period were not similar to those found with combined hypnosis and

  10. International Infantry and Joint Services Small Arms Systems Annual Symposium Exhibition and Firing Demonstration

    DTIC Science & Technology

    2005-05-19

    Noon Awards Luncheon Chinn Award Presentation Mr. Richard Audette, Chinn Award Recipient, 2005 Presented by Mr. Joel Goldman Hathcock ...Award Presentation Mr. Christopher P. Mitternight, Hathcock Award Recipient, 2005 Presented by Mr. Charles Buxton 1:30 - 5 PM Concurrent Sessions...973) 724-6059 Excalibur PM, LTC William Cole (973) 724-3152 DPM, Chris Grassano (973) 724-5246 Advanced Systems DC, Steve Hromnak (973) 724-5476

  11. ARO/ARL Site Visit Project Review Presentation

    DTIC Science & Technology

    2012-07-01

    hemodynamic activity. 7/11/2012 Challenges 10 complicated equipment gradient artifact BCG artifact How to combine the data? bias field auditory...noise 7/11/2012 11 A B C + + – – Our Solutions EEG+ BCG BCG 7/11/2012 12 (Goldman et al., Neuroimage 2009) Observing latent...Discrimination Results model human subjects Neurometric curve NOT optimized to match psychometric curve! human subjects model ( matrix word

  12. Migratory Sleeplessness in the White-Crowned Sparrow (Zonotrichia leucophrys gambelii)

    DTIC Science & Technology

    2004-07-01

    behaviors occur in virtually all organisms, ranging from insects to mammals (Goldman et al. 2004). Just as circadian rhythms allow organisms to anticipate...conditions. Like circadian rhythms , seasonal migratory behavior is both endogenously generated and shaped by external factors such as photoperiod length...linked to alterations in the circadian rhythm during migration. In particular, since the occurrence of REM sleep is closely tied to the circadian

  13. Goal-Driven Autonomy in a Navy Strategy Simulation

    DTIC Science & Technology

    2010-01-01

    Goldman R . (2007). Hotride: Hierarchical ordered task replanning in dynamic environments. In F. Ingrand, & K. Rajan (Eds.) Planning and Plan...www.mbari.org/autonomy/ICAPS07-workshop] van den Briel, M., Sanchez, R ., Do, M.B., & Kambhampati, S. (2004). Effective approaches for partial satisfaction...Perpetual self-aware cognitive agents. AI Magazine, 28(1), 32-45. Dearden, R ., Meuleau, N., Ramakrishnan, S., Smith, D., & Washington, R . (2003

  14. Investigation of the Atmospheric Propagation of Alkali Lasers in a Maritime Environment Using Tunable Diode Laser Atmospheric Spectroscopy

    DTIC Science & Technology

    2013-03-01

    which is given as (6) where is the FWHM of a Doppler broadened lineshape, given as...magnitude higher than the Doppler broadened width, the pressure broadened FWHM is not sufficiently large to entirely dominate the overall FWHM. Because...Electronics. Prentice Hall, USA, 1995. 8. L. S. Rothman, C. P. Rinsland, A. Goldman , S. T. Massie, D. P. Edwards, J.-M. Flaud, A. Perrin, C. Camy

  15. Integration of Hierarchical Goal Network Planning and Autonomous Path Planning

    DTIC Science & Technology

    2016-03-01

    Conference on Robotics and Automation (ICRA); 2010 May 3– 7; Anchorage, AK. p. 2902–2908. 4. Ayan NF, Kuter U, Yaman F, Goldman RP. Hotride...DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT Automated planning has...world robotic systems. This report documents work to integrate a hierarchical goal network planning algorithm with low-level path planning. The system

  16. Analysis of MALDI-TOF Serum Profiles for Biomarker Selection and Sample Classification

    DTIC Science & Technology

    2005-01-01

    these five m/z windows as its inputs yielded 92% sensitivity and 90% specificity in distinguishing hepatocellular carcinoma (HCC) patients from...Cubizolles, I. Laurendeau, and P. Bedossa, "Identification of a new marker of hepatocellular carcinoma by serum protein profiling of patients with chronic...Goldman, "Enrichment of low molecular weight fraction of serum for mass spectrometric analysis of peptides associated with hepatocellular carcinoma ," Submitted

  17. Training the Future - Interns Harvesting & Testing Plant Experim

    NASA Image and Video Library

    2017-07-19

    In the Space Life Sciences Laboratory at NASA's Kennedy Space Center in Florida, student interns such as Emma Boehm, left, and Jessica Scotten are joining agency scientists, contributing in the area of plant growth research for food production in space. Boehm is pursuing a degree in ecology and evolution at the University of Minnesota. Scotten is majoring in microbiology at Oregon State University. The agency attracts its future workforce through the NASA Internship, Fellowships and Scholarships, or NIFS, Program.

  18. Complete mitochondrial genomes of three crickets (Orthoptera: Gryllidae) and comparative analyses within Ensifera mitogenomes.

    PubMed

    Yang, Jing; Ren, Qianli; Huang, Yuan

    2016-03-17

    The complete mitochondrial genomes (mitogenomes) of Velarifictorus hemelytrus, Loxoblemmus equestris and Teleogryllus emma are 16123 bp, 16314 bp and 15697 bp, in size, respectively. All three mitogenomes possess the same gene order of the inversion of the gene cluster trnE-trnS(AGN)-trnN compared with the ancestral gene order of Orthoptera. The atypical initiation codon for the cox1 gene in three crickets is TTA. Pronounced A skew and T skew have been found in Grylloidea comparing with Gryllotalpoidea and Tettigonioidea. The T-stretch in the minority strand is interrupted by C to form (T)n(C)2(T)n sequences in five species of Gryllinae (V. hemelytrus, L. equestris, T. emma, T. oceanicus, T. commodus). This T-stretch variant with its neighbouring A-stretch variant (A-stretch is interrupted by G), which were discovered in the A+T-rich regions of all taxa from infraorder Gryllidea, could form a conserved stem-loop structure (including 15 ~ 17 base pairs). This potential stem-loop structure is a favorable candidate that may participate in the replication origin of the minority strand of Gryllidea mitogenome. Phylogenetic analysis indicated that within the Gryllinae, genus Teleogryllus and Velarifictorus are closely related, sister to the genus Loxoblemmus. The relationships among the five superfamilies of Ensifera presented here were ((Grylloidea, Gryllotalpoidea) (Tettigonioidea, (Hagloidea, Rhaphidophoroidea))).

  19. Cyclic joint remote state preparation in noisy environment

    NASA Astrophysics Data System (ADS)

    Zhang, Chang-yue; Bai, Ming-qiang; Zhou, Si-qi

    2018-06-01

    We propose a scheme of cyclic joint remote state preparation for three sides, which takes advantage of three GHZ states to compose product state as quantum channel. Suppose there are six legitimate participants, says Alice, Bob, Charlie, David, Emma and Fred in the scheme. It can be shown that Alice and David can remotely prepare a single-qubit state on Bob's side; meanwhile, Bob and Emma can remotely prepare a desired quantum state on Charlie's side, and Charlie and Fred can also remotely prepare a single-qubit state on Alice's side at the same time. Further, it can be achieved in the opposite direction of the cycle by changing the quantum channel. Based on it, we generalize this protocol to N (N≥3) sides utilizing three multi-qubit GHZ-type states as quantum channel. Therefore, the scheme can achieve cyclic joint remote state preparation, which remotely prepares N states in quantum network with N-party, simultaneously. In addition, we consider that the effect of amplitude-damping noise of the initial states is prepared in four different laboratory. Clearly, we use fidelity to describe how much information has been lost in the cyclic process. Our investigation about the effect of noise shows that the preparing of the initial state in different laboratories will affect the loss of information.

  20. Sean and David Goldman International Child Abduction Prevention and Return Act of 2013

    THOMAS, 113th Congress

    Rep. Smith, Christopher H. [R-NJ-4

    2013-05-13

    House - 06/14/2013 Referred to the Subcommittee on Crime, Terrorism, Homeland Security, and Investigations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  1. Sean and David Goldman International Child Abduction Prevention and Return Act of 2014

    THOMAS, 113th Congress

    Sen. Menendez, Robert [D-NJ

    2014-06-19

    Senate - 06/19/2014 Read twice and referred to the Committee on Foreign Relations. (All Actions) Notes: For further action, see H.R.3212, which became Public Law 113-150 on 8/8/2014. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  2. The Second Garnet Compendium: Collected Papers 1990-1992.

    DTIC Science & Technology

    1993-02-01

    BELIEF Robert Goldman Russell Almond 33. Tulane University, CS 12. The MITRE Corporation THESEUS AIMI (An Intelligent Multimedia Interface) Raymond Lang...These are images of windows from the THESEUS application used by the Tulanc University Computer Science Department on guided tours of the department given...to visiting high school seniors and other interested paries. THESEUS is intended to be used as part of a presentation on what the study of computcr

  3. Core Temperature and Surface Heat Flux During Exercise in Heat While Wearing Body Armor

    DTIC Science & Technology

    2015-10-26

    Table 7, overall dry > humid, there were no significant differences for energy costs (M) between environments. When compared to the estimated M...KB, Givoni B, & Goldman RF. Predicting energy expenditure with loads while standing or walking very slowly. J Appl Physiol 43(4): 577-581, 1977...No. 0704-0188 The public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for

  4. Team Dimensions: Their Identity, Their Measurement and Their Relationships

    DTIC Science & Technology

    1985-01-01

    business games (e.g., Cummings, Huber & Arendt, 1974; Kennedy, 1971 ). Apart from the problem solving tasks, the second largest group of studies...positive relationship between size and number of answers on. an anagram task. In a disjunctive problem, solving-task-, Frank & Anderson ( 1971 ) found that...4, or 5 members. However, there were no differences between the groups in time to solutions. Goldman ( 1971 ) found posi’tive effects for size with

  5. Combat Readiness Check (CRC): Development of a Dual Task Assessment Protocol to Assist with Return-to-Duty Decision-Making After Traumatic Brain Injury

    DTIC Science & Technology

    2010-10-01

    injury CO-PRINCIPAL INVESTIGATORS: Mary Vining Radomski, PhD, OTR/L and Maggie Weightman, PT, PhD (Sister Kenny Research Center [SKRC]) CO...INVESTIGATORS: Leslie Davidson PhD (Cand), MS, OTR/L (Riverbend); MAJ Sarah Goldman PhD, OTR/L, CHT (United States Army Research Institute of Environmental...of Minnesota) ASSISTED BY: Dr. Kristin Heaton and Amanda Antczak (USARIEM) and Marsha Finkelstein (health services researcher ), Michelle Pose, and

  6. The STRIVE-ONR Project: Stress Resistance in Virtual Environments

    DTIC Science & Technology

    2015-07-29

    from the Virtual Iraq/Afghanistan Virtual Reality Exposure Therapy (VRET) system at the University of Southern California Institute for Creative...better sense of health outcomes; that is, "how the social environment exerts a cumulative impact on the physical and mental well being of individuals...levels with functional decline in elderly men and women. Geriatrics & gerontology international, 9 3, 282-289. Goldman, N., Turra, C. M., Glei, D

  7. Consequences of Variations in Genes that affect Dopamine in Prefrontal Cortex

    PubMed Central

    Diamond, Adele

    2008-01-01

    Patricia Goldman-Rakic played a groundbreaking role in investigating the cognitive functions subserved by dorsolateral prefrontal cortex and the key role of dopamine in that. The work discussed here builds on that including: 1) Studies of children predicted to have lower levels of prefrontal dopamine but otherwise basically normal brains (children treated for phenylketonuria [PKU]). Those studies changed medical guidelines, improving the children’s lives. 2) Studies of visual impairments (in contrast sensitivity and motion perception) in PKU children due to reduced retinal dopamine and due to excessive phenylalanine during the first postnatal weeks. Those studies, too, changed medical guidelines. 3) Studies of working memory and inhibitory control differences in typically developing children due to differences in catechol-O-methyltransferase (COMT) genotype, which selectively affect prefrontal dopamine levels. 4) Studies of gender differences in the effect of COMT genotype on cognitive performance in older adults. 5) A hypothesis about fundamental differences between attention deficit hyperactivity disorder (ADHD) that includes hyperactivity and ADHD of the inattentive type. Those disorders are hypothesized to differ in the affected neural system, underlying genetics, responsiveness to medication, comorbidities, and cognitive and behavioral profiles. These sound quite disparate but they all grew systematically out the base laid down by Patricia Goldman-Rakic. PMID:17725999

  8. Effect of negative mechanical stress on the orientation of myosin cross-bridges in muscle fibers.

    PubMed Central

    Burghardt, T P; Ajtai, K

    1989-01-01

    The effect of positive and negative stress on myosin cross-bridge orientation in glycerinated muscle fibers was investigated by using fluorescence polarization spectroscopy of the emission from the covalent label tetramethyl-rhodamine-5-(and -6)-iodoacetamide (IATR) specifically modifying sulfhydryl one (SH1) on the myosin heavy chain. Positive tension was applied by stretching the fiber in rigor. Negative tension was applied in two steps by using a protocol introduced by Goldman et al. [Goldman, Y. E., McCray, J. A. & Vallette, D. P. (1988) J. Physiol. (London) 398, 75P]: relaxing a fiber at resting length and stretching it until the relaxed tension is appreciable and then placing the fiber in rigor and releasing the tension onto the rigor cross-bridges. We found, as have others, that positive tension has no effect on the fluorescence polarization spectrum from the SH1-bound probe, indicating that the cross-bridge does not rotate under these conditions. Negative tension, however, causes a change in the fluorescence polarization spectrum that indicates a probe rotation. The changes in the polarization spectrum from negative stress are partially reversed by the subsequent application of positive stress. It appears that negative tension strains the cross-bridge, or the cross-bridge domain containing SH1, and causes it to rotate. Images PMID:2526336

  9. Emma Willard Students Illustrate New Children's Book about Feisty Female Characters

    ERIC Educational Resources Information Center

    Gross, Karen

    2016-01-01

    "Lady Lucy's Quest" (Shires Press) is a story about a feisty young girl in the Middle Ages who wants to become a Knight of the Round Table. The initial reaction of her family, the townspeople, and the knights is, stated simply, "no way." But Lucy perseveres and meets the three challenges of knighthood presented to her, albeit…

  10. NASA Day at the Capitol

    NASA Image and Video Library

    2009-02-19

    Astronaut Rex Walheim (center) speaks to members of the Mississippi House of Representatives in chambers during NASA Day at the Capitol in Jackson on Feb. 19. Walheim was joined at the podium by members of the Mississippi House of Representatives Gulf Coast delegation, as well as Stennis Space Center Director Gene Goldman (astronaut's immediate right) and NASA's Shared Services Center Director Rick Arbuthnot and Partners for Stennis Executive Director Tish Williams (astronaut's immediate left).

  11. NASA Explorer School

    NASA Image and Video Library

    2007-11-08

    The NASA Explorer School-East Oktibbeha County School District team recently celebrated the start of its three-year partnership with NASA during a two-part kickoff event Nov. 7 and 8. Pictured from left are, Oktibbeha County School District Superintendent Dr. Walter Conley; NES Team Administrator James Covington; Stennis Space Center Deputy Director Gene Goldman; Sharon Bonner; NES Team Lead Yolanda Magee; Andrea Temple; Carolyn Rice; and special guest astronaut Roger Crouch.

  12. NASA Explorer School

    NASA Technical Reports Server (NTRS)

    2007-01-01

    The NASA Explorer School-East Oktibbeha County School District team recently celebrated the start of its three-year partnership with NASA during a two-part kickoff event Nov. 7 and 8. Pictured from left are, Oktibbeha County School District Superintendent Dr. Walter Conley; NES Team Administrator James Covington; Stennis Space Center Deputy Director Gene Goldman; Sharon Bonner; NES Team Lead Yolanda Magee; Andrea Temple; Carolyn Rice; and special guest astronaut Roger Crouch.

  13. 30TH Annual Conference of the Military Testing Association Held in Arlington, Virginia on 27 November-2 December 1988

    DTIC Science & Technology

    1988-12-02

    S95-S120. Goldman, Alvin I. 197G. A Theorv of Human Action. Englewood Cliffs, NJ: Prentice Hall. Jones, Robe’ct Alun 1986. " Durkheim , Frazer, and...34) (I . 4 , 1r f emil (’ i. ( 1&.7’ r,, Ftni:i in, 4 04 (4 .T i aIre black , 74 (1.’l? ) ; r,, Ilispaini , I i,: ( . I1 Ve 0 thl ,r minor i t i.s an

  14. Photocopy of photograph. Photographer unknown. Typical suggestion award photograph from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph. Photographer unknown. Typical suggestion award photograph from the World War II period. Useful suggestions were awarded a $ 50 bond and usually a photo in the shipyard newspaper, the beacon. This photo shows an improved bilge block template layout table left to right: Stuart S. Sanders, Rosalie Moschella, Eddie Ormond, Lt. CDR. J.M. Ballinger, and A.A. Goldman. - Naval Base Philadelphia-Philadelphia Naval Shipyard, League Island, Philadelphia, Philadelphia County, PA

  15. NASA Day at the Capitol

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Astronaut Rex Walheim (center) speaks to members of the Mississippi House of Representatives in chambers during NASA Day at the Capitol in Jackson on Feb. 19. Walheim was joined at the podium by members of the Mississippi House of Representatives Gulf Coast delegation, as well as Stennis Space Center Director Gene Goldman (astronaut's immediate right) and NASA's Shared Services Center Director Rick Arbuthnot and Partners for Stennis Executive Director Tish Williams (astronaut's immediate left).

  16. Refighting the Last War: Afghanistan and the Vietnam Template

    DTIC Science & Technology

    2009-12-01

    2 November-December 2009  MILITARY REVIEW Thomas H. Johnson is a research professor for the Department of Na- tional Security Affairs and director...Valley of Afghanistan’s Wardak Province, 19 August 2009. (AP Photo, David Goldman) Thomas H. Johnson and M. Chris Mason IT IS AN oft-cited maxim that...in Afghanistan. President Obama certainly knows, as Presidents Johnson and Nixon did in similar circumstances, that the choice of alter- natives now

  17. Field Test Data for Detecting Vibrations of a Building Using High-Speed Video Cameras

    DTIC Science & Technology

    2017-10-01

    ARL-TR-8185 ● OCT 2017 US Army Research Laboratory Field Test Data for Detecting Vibrations of a Building Using High -Speed Video...Field Test Data for Detecting Vibrations of a Building Using High -Speed Video Cameras by Caitlin P Conn and Geoffrey H Goldman Sensors and...June 2016 – October 2017 4. TITLE AND SUBTITLE Field Test Data for Detecting Vibrations of a Building Using High -Speed Video Cameras 5a. CONTRACT

  18. Coordinated Radar and Aircraft Observations of Turbulence.

    DTIC Science & Technology

    1981-05-26

    VELOCITY (il/) Jig. 10. Spectrum at two points having excessive radar c / 23 ACKNOWLEDGMENr The direction and support of Mr. 1. Goldman of the FAA...of Doppler Weather Radar to Turbulence Measure- ments Which Affect Aircraft," FAA Report RD-77-145 (March 1977). 2. R. T. Strauch, "Applications of...Meteorological Doppler Radar for Weather- Surveillance Near Air Terminals", IEEE Trans. Geosci. Electron., G15-17, 4 (1979). 3. P. B. MacCready

  19. Space Plants for Astronaut Consumption

    NASA Technical Reports Server (NTRS)

    Mickens, Matthew A.; Grandpre, Ayla Moriah; Boehm, Emma; Barnwell, Payton

    2017-01-01

    Growing plants in space will be an essential part of sustaining astronauts during long-range missions. During the summer of 2017, three female NASA interns, have been engaged in research relevant to food production in space, and will present their projects to an all female program known as Girls in STEM camp. Ayla Grandpre, a senior from Rocky Mountain College, has performed data mining and analysis of crop growth results gathered through Fairchild Botanical Gardens program, Growing Beyond Earth. Ninety plants were downselected to three for testing in controlled environment chambers at KSC. Ayla has also managed an experiment testing a modified hydroponics known as PONDS, to grow mizuna mustard greens and red robin cherry tomatoes. Emma Boehm, a senior from the University of Minnesota, has investigated methods to sterilize seeds and analyzed the most common microbial communities on seed surfaces. She has tested a bleach fuming method and an ethanol treatment. Emma has also tested Tokyo bekana Chinese cabbage seeds from four commercial seed vendors to identity differences in germination and growth variability. Lastly, Payton Barnwell, a junior from Florida Polytechnic University has shown that light recipes provided by LEDs can alter the growth and nutrition of 'Outredgeous' lettuce, Chinese cabbage, and Mizuna. The results of her light quality experiments will provide light recipe recommendations for space crops that grown in the Advanced Plant Habitat currently aboard the International Space Station.

  20. Ultrafast Photovoltaic Response in Ferroelectric Nanolayers

    DTIC Science & Technology

    2016-04-19

    Hesse, and M. Alexe, Phys. Rev. Lett. 98, 257601 (2007). [28] P. Emma, R. Akre , J. Arthur, R. Bionta, C. Bostedt, J. Bozek, A . Brachmann, P...David M. Fritz10, Marco Cammarata10, Diling Zhu10, Henrik T. Lemke10,11, Donald A . Walko4, Eric M. Dufresne4, Yuelin Li4, Jörgen Larsson12, David A ...Reis2,9,13, Klaus Sokolowski-Tinten7, Keith A . Nelson6, Andrew M. Rappe5, Paul H. Fuoss3, G. Brian Stephenson3 and Aaron M. Lindenberg2,8.9

  1. State of STEM (SoSTEM) Address

    NASA Image and Video Library

    2014-01-29

    Dr. John P. Holdren, Assistant to the President for Science and Technology and Director of the White House Office of Science & Technology Policy, left, is interviewed by Montgomery Blair High School Student Newspaper “Silver Chips” Online Editor-in-Chief Aanchal Johri, center, and Photo Editor Emma Howells, from Silver Spring, MD. ahead of the annual White House State of Science, Technology, Engineering, and Math (SoSTEM) address, Wednesday, Jan. 29, 2014, in the South Court Auditorium in the Eisenhower Executive Office Building on the White House complex in Washington. Photo Credit: (NASA/Bill Ingalls)

  2. STS-126 crew visit

    NASA Image and Video Library

    2009-01-13

    Stennis Space Center Director Gene Goldman (center) stands with astronauts Christopher Ferguson (right) and Heidemarie Stefanyshyn-Piper in front of the A-2 Test Stand during the space shuttle crew members' visit to NASA's rocket engine testing facility Jan. 13. During their visit, Ferguson and Stefanyshyn-Piper reported on the STS-126 space shuttle delivery and servicing mission to the International Space Station. Ferguson served as commander of the mission. Stefanyshyn-Piper served as a mission specialist.

  3. NASA honors Apollo 13 astronaut Fred Haise Jr.

    NASA Image and Video Library

    2009-12-02

    Apollo 13 astronaut and Biloxi native Fred Haise Jr. was honored for a lifetime of achievement with NASA's Ambassador of Exploration Award during a Dec. 2 ceremony at Gorenflo Elementary School in Biloxi. Haise subsequently presented the moon rock award to Gorenflo for display at the school. Participating in the ceremony were (l to r): Gorenflo Principal Tina Thompson, NASA Administrator Charles Bolden, Haise, Biloxi Public School District Superintendent Paul Tisdale and Stennis Director Gene Goldman.

  4. Irreversible Catalyst Activation Enables Hyperpolarization and Water Solubility for NMR Signal Amplification by Reversible Exchange

    DTIC Science & Technology

    2016-09-12

    Phys. Rev. Lett. 1986 , 57, 2645−2648. (8) Goldman, M.; Johannesson, H. Conversion of a Proton Pair Para Order into C-13 Polarization by Rf...A.; Harris, K.; Batchelder, L. S.; Bhattacharya, P.; Ross , B. D.; Weitekamp, D. P. PASADENA Hyperpolarization of Succinic Acid for MRI and NMR...Bhattacharya, P.; Chekmenev, E. Y.; Perman, W. H.; Harris, K. C.; Lin, A. P.; Norton, V. A.; Tan, C. T.; Ross , B. D.; Weitekamp, D. P. Towards

  5. Selective DNA-Mediated Assembly of Gold Nanoparticles on Electroded Substrates

    DTIC Science & Technology

    2008-06-01

    might use the Watson - Crick base-pairing of DNA as a means for ultrahigh-precision engineering is well- known.5,6 The idea is to use the highly specific...Selective DNA -Mediated Assembly of Gold Nanoparticles on Electroded Substrates K. E. Sapsford,†,‡,∇ D. Park,§ E. R. Goldman,‡ E. E. Foos,| S. A...electrodes via DNA hybridization. Protocols are demonstrated for maximizing selectivity and coverage using 15mers as the active binding agents. Detailed

  6. Reintegrating Troops with Mild Traumatic Brain Injury (mTBI) into Their Communities: Understanding the Scope and Timeline of Post-Deployment Driving Problems

    DTIC Science & Technology

    2012-08-01

    features/ptsd.asp http://www .ndtv .com/article/ world /back-from- war -fear-and-danger-fill-driver-s- seat-165831 • Refereed Research Posters: o Goldman SB...OMB No. 0704-0188 Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for...NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1 . REPORT DATE (DD-MM-YYYY) 2. REPORT TYPE 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE 5a

  7. Employee Attitudes Within the Air Traffic Organization

    DTIC Science & Technology

    2004-12-01

    ownership of ATOEC decisions • Do what you say you are going to do • Approve programs consistent with available funds/resources Item 23: Some employees ... Employee Attitudes Within the Air Traffic Organization Carla A. Hackworth1 Crystal E. Cruz1 Dan G. Jack2 Scott Goldman1 S. Janine King2 1Civil...DOT/FAA/AM-04/23 4. Title and Subtitle 5. Report Date December 2004 Employee Attitudes Within the Air Traffic Organization 6. Performing

  8. Comparison of Gutta Percha Filling Techniques. Part 2. Three Chloroform-Gutta Percha Filling Techniques.

    DTIC Science & Technology

    1980-06-01

    in evaluators and the evaluation method. Also in Goldman’s study reagents, nitric acid and sodium hypochlorite , were used in retrieving the gutta...Inlo Di-5r7W~f~ IU* Report) DTIC illE LECTE f_ IS. KEY WORDS (Conthue on revere* side It necessay and Identify by block numbei) -. , endodontics ...TECHNIQUES. PART 2: THREE CHLOROFORM-GUTTA PERCHA FILLING TECHNIQUES M. Wong, DDS Resident, Endodontics Dept. of Dentistry - PO Box 59 Madigan Army Medical

  9. Gyrotropic Guiding-Center Fluid Theory for the Turbulent Heating of Magnetospheric Ions in Downward Birkeland Current Regions

    DTIC Science & Technology

    2006-11-20

    Doppler -shifted, quasistatic turbulence from the real, time- mogeneous medium,18 we can then estimate that k - k1 and dependent turbulence near the...ground is due to Doppler -shifted, spatially irregular, electric- field structures that are stationary in the ion frame. Sub- we have determined that the...erpnding cn ar ion tepeoratre- 18F J. Crary, M. V. Goldman , R. E. Ergun, and D. L. Newman, Geophys. sented in this paper gives the perpendicular ion

  10. STS-126 crew visit

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Stennis Space Center Director Gene Goldman (center) stands with astronauts Christopher Ferguson (right) and Heidemarie Stefanyshyn-Piper in front of the A-2 Test Stand during the space shuttle crew members' visit to NASA's rocket engine testing facility Jan. 13. During their visit, Ferguson and Stefanyshyn-Piper reported on the STS-126 space shuttle delivery and servicing mission to the International Space Station. Ferguson served as commander of the mission. Stefanyshyn-Piper served as a mission specialist.

  11. Map showing thickness of young bay mud, southern San Francisco Bay, California

    USGS Publications Warehouse

    McDonald, Sandra D.; Nichols, Donald R.; Wright, Nancy A.; Atwater, Brian

    1978-01-01

    Soft water-saturated estuarine deposits less than 10,000 years old underlie the southern part of San Francisco bay and the present and former marshlands that border the bay. Known locally as bay mud or as young bay mud, these deposits, and the estuarine environment that produces them, are of major importance in making decision on land use and development in the San Francisco Bay area. Knowledge of the distribution, thickness, and physical properties of young bay mud is critical to the feasibility, design, and maintenance of structures built on it. Fore this reason, numerous attempts have been made in the past to map or describe these characteristics (Mitchell, 1963; Goldman, 1969; McDonald and Nichols, 1974). The accompanying map of bay-mud thickness significantly revises part of an earlier compilation by Kahle and Goldman (1969) and includes new data from approximately 2400 boreholes, most of which have been drilled during the past 15 years. It also incorporates information on historic margins of San Francisco Bay and its tidal marshes (Nichols and Wright, 1971). Although this map was compelled mostly from data gathered during foundation investigations and construction projects, it is mostly from data gathered during foundation investigations and construction projects, it is not a substitute for such studies. Rather, the map provides regional information for land-use planning, seismic zonation, and design of foundation investigations.

  12. Movement of Cations through Cuticles of Citrus aurantium and Acer saccharum1

    PubMed Central

    Tyree, Melvin T.; Tabor, Christopher A.; Wescott, Charles R.

    1990-01-01

    We examined some biophysical mechanisms of ion migration across leaf cuticles enzymatically isolated from Acer saccharum L. and Citrus aurantium L. leaves. Diffusion potential measurements were used to calculate the permeabilities of Cl-, Li+, Na+, and Cs+ ions all as a ratio with respect to the permeability of K+ in cuticles. In 2 millimolar ionic strength solutions the permeability sequence from high to low was K = Cs > Na > Li » Cl. When the outer and inner surfaces of cuticles were bathed in artificial precipitation and artificial apoplast, respectively, diffusion potentials ranging from −52 to −91 millivolts were measured (inside negative). The Goldman equation predicted that the measured potentials were enough to increase the driving force on the accumulation of heavy metals by a factor of 4 to 7. Other ions migrate with forces 3 to 10 times less than predicted by the Goldman equation for concentration differences alone. Our analysis showed that Ca2+, and perhaps Mg2+, might even be accumulated against concentration gradients under some circumstances. Their uptake was apparently driven by the diffusion potentials created by the outward migration of monovalent salts. We feel that future models predicting leaching of nutrients from trees during acid rain events must be modified to account for the probable influence of diffusion potentials on ion migration. PMID:16667677

  13. Effects of Perchlorate on Thyroidal Uptake of Iodide with Corresponding Hormonal Changes

    DTIC Science & Technology

    2000-07-01

    with iodide for uptake at this iodide-concentrating step (Goldman and Stanbury, 1973), potentially leading to hypothyroidism . As a result perchlorate...TSH can result in increased thyroid weight, goiter and hypothyroidism (Fukuda et al., 1975; Gerber et al., 1981). The objective of this study was to...2000) "• Canine T3 kits ( canine T3 calibrators batch # C3D3-8, expired July 31, 1999; 1251 canine T 3 batch #, TC32, expired July 31, 1999; canine T3

  14. Exploratory Development of an Electrically Rechargeable Lithium Battery.

    DTIC Science & Technology

    1980-10-01

    RECHARGEABLE LITHIUM BATTERY O K. M. Abraham GtJ. L. Goldman ~M. D. Dempsey MCG. L. Holleck EIC Laboratories, Inc. " - 55 Chapel Street Newton, MA 02158 October...COVERED (, Epl.oratory Development of an Electrically 7 9FINAL REPORT- 7-2-79 to 7-1-80 Rechargeable Lithium Battery * .. PFORMIN ORO. RE RT NUMBER 7...Bloek 20, Il diiItrent hurm Reprt) I. SUPPLEMENTARY NOTES IS. KEY WORDS (Continue n Mrverse side It necesary and identify by block number) Vanadium

  15. A Comparison of Three Curve Intersection Algorithms

    NASA Technical Reports Server (NTRS)

    Sederberg, T. W.; Parry, S. R.

    1985-01-01

    An empirical comparison is made between three algorithms for computing the points of intersection of two planar Bezier curves. The algorithms compared are: the well known Bezier subdivision algorithm, which is discussed in Lane 80; a subdivision algorithm based on interval analysis due to Koparkar and Mudur; and an algorithm due to Sederberg, Anderson and Goldman which reduces the problem to one of finding the roots of a univariate polynomial. The details of these three algorithms are presented in their respective references.

  16. Compilation of Reprints Number 58, Office of Naval Research.

    DTIC Science & Technology

    1981-09-01

    ATLANTICA, GONOSTOMA ATLANTICUM, AND APHANOPUS CARBO, WITH NOTES ON THE ANATOMY OF APHANOPUS CARBO’ - ... Kevin M. Howe, David L. Stein and Carl E. Bond...REPORT NUMBR APHANOPUS CARBO 7. AUTHOR(. ) 8. CONTRACT OR GRANT NUMBER(@) Kevin M. Howe David L. Stein N00014-67-A-0369-007 Carl E. Bond 9...E Tyler. and C. R. Goldman Optical properties and show inTabe I or achof erlo’s 197] waer ype an 4922 ZANEVELD AND SPINRAD: IRRADIANCE IN THE SEA

  17. Clustering Similarity Digest Bloom Filters in Self-Organizing Maps

    DTIC Science & Technology

    2012-12-01

    www.sciencedirect.com/science/article/ pii/S1742287610000368 [4] M. Rogers, J . Goldman, R. Mislan, T. Wedge, and S. Debrota, “Computer forensics field triage...1990. [9] T. Kohonen, S. Kaski, K. Lagus, J . Salojarvi, J . Honkela, V. Paatero, and A. Saarela, “Self organization of a massive document collection...the IEEE-INNS-ENNS Interna- tional Joint Conference on, vol. 6, 2000, pp. 15 –19 vol.6. [12] G. Salton , A. Wong, and C. Yang, “A vector space model for

  18. Terahertz Atmospheric Attenuation and Continuum Effects

    DTIC Science & Technology

    2013-05-01

    comparison of the two pressure-broadened line shapes as well as a Doppler -broadened line shape. As can be seen in the figure, the effect of foreign gas...Conference  April  29-­‐May  3,  2013,  Baltimore,  MD   Figure 2. A Doppler -broadened absorption line with the partial pressure of... Goldman , A., Jacquemart, D., Kleiner, I., Lacome, N., Lafferty, W. J., Mandin, J. Y., Massie, S. T., Mikhailenko, S. N., Miller, C. E., Moazzen

  19. "So it really does exist-the sea-Serpent we've never believed in!" Ferenczi's influence on Freud revisited.

    PubMed

    Bonomi, Carlo

    2013-12-01

    In the last phase of his work, Ferenczi created a new language for trauma, based on the fragmentation of mental life. In the paper on "The principles of relaxation and neocatharsis," Ferenczi reformulated the goal of analysis by proposing that "no analysis can be regarded … as complete unless we have succeed in penetrating the traumatic material", where the "traumatic material" was not to be sought in the neurotic reactions and adaptive solutions of the ego but in more primitive reactions, such as the psychotic turning away from reality, splitting, and fragmentation. This was exactly the material that Freud assimilated in the essay "A disturbance of memory on the Acropolis", after the death of Ferenczi. Freud visited Athens in 1904, and the walk up to the Parthenon represented the successful coronation of his self-analysis. Actually, the hallucination turned out to be so uncanny that he never again visited Athens. In a letter to Fliess, written shortly before the meeting in Nuremberg, on January 24, 1897, Freud reported on a case history turning on a "scene about the circumcision of a girl," who later was convincingly identified by Schur as Emma Eckstein. Did Freud have the germinal idea that Emma Eckstein's hallucination of the penis contained the wish to overcome her trauma and the hope to have a restored genital? Is this the holy visitation, which haunted him on the Acropolis? Why did he give up the profound insight that the dreams of gigantic snakes had a traumatic origin?

  20. Psychosocial care for children with haemophilia and their parents in the Netherlands.

    PubMed

    Limperg, P F; Haverman, L; Beijlevelt, M; van der Pot, M; Zaal, G; de Boer, W A; Fijnvandraat, K; Peters, M; Grootenhuis, M A

    2017-05-01

    Children growing up with haemophilia are at greater risk for psychosocial problems than their healthy peers. Providing psychosocial care to children with haemophilia and their families is indispensable, since psychosocial factors can have a significant impact on health and health-related quality of life (HRQOL). Our aim was to give a description of psychosocial care provided by the multidisciplinary team of the Hemophilia Comprehensive Care Centre (HCCC) at the Emma Children's Hospital in Amsterdam, the Netherlands. With this overview, other caregivers and hospitals can benefit in organizing their psychosocial care for children with haemophilia. The focus of the psychosocial care provided by the multidisciplinary team is on preventing psychosocial problems and medical-related stress, and supporting and equipping the child with haemophilia and its parents with as many skills as possible to lead an independent life with a high HRQOL. Core elements of the psychosocial care are therefore monitoring and screening of HRQOL (e.g. in daily clinical practice via www.hetklikt.nu), psychoeducation (haemophilia camp, haemophilia school, disease-specific activities, meetings for girls, parent meetings), practical help (Emma at Work, an employment agency for adolescents and young adults; Educational Facility and school visits), psychosocial interventions (the On Track group intervention and the Haemophilia Coping and Perception Test) and individual care (psychological counselling and referrals). By providing this overview of psychosocial support offered and by sharing this knowledge, psychosocial care can become more structured and consistent between HCCCs around the world. Potentially, processes and outcomes of care can be improved. © 2017 John Wiley & Sons Ltd.

  1. Only pick the right grains: Modelling the bias due to subjective grain-size interval selection for chronometric and fingerprinting approaches.

    NASA Astrophysics Data System (ADS)

    Dietze, Michael; Fuchs, Margret; Kreutzer, Sebastian

    2016-04-01

    Many modern approaches of radiometric dating or geochemical fingerprinting rely on sampling sedimentary deposits. A key assumption of most concepts is that the extracted grain-size fraction of the sampled sediment adequately represents the actual process to be dated or the source area to be fingerprinted. However, these assumptions are not always well constrained. Rather, they have to align with arbitrary, method-determined size intervals, such as "coarse grain" or "fine grain" with partly even different definitions. Such arbitrary intervals violate principal process-based concepts of sediment transport and can thus introduce significant bias to the analysis outcome (i.e., a deviation of the measured from the true value). We present a flexible numerical framework (numOlum) for the statistical programming language R that allows quantifying the bias due to any given analysis size interval for different types of sediment deposits. This framework is applied to synthetic samples from the realms of luminescence dating and geochemical fingerprinting, i.e. a virtual reworked loess section. We show independent validation data from artificially dosed and subsequently mixed grain-size proportions and we present a statistical approach (end-member modelling analysis, EMMA) that allows accounting for the effect of measuring the compound dosimetric history or geochemical composition of a sample. EMMA separates polymodal grain-size distributions into the underlying transport process-related distributions and their contribution to each sample. These underlying distributions can then be used to adjust grain-size preparation intervals to minimise the incorporation of "undesired" grain-size fractions.

  2. pLARmEB: integration of least angle regression with empirical Bayes for multilocus genome-wide association studies.

    PubMed

    Zhang, J; Feng, J-Y; Ni, Y-L; Wen, Y-J; Niu, Y; Tamba, C L; Yue, C; Song, Q; Zhang, Y-M

    2017-06-01

    Multilocus genome-wide association studies (GWAS) have become the state-of-the-art procedure to identify quantitative trait nucleotides (QTNs) associated with complex traits. However, implementation of multilocus model in GWAS is still difficult. In this study, we integrated least angle regression with empirical Bayes to perform multilocus GWAS under polygenic background control. We used an algorithm of model transformation that whitened the covariance matrix of the polygenic matrix K and environmental noise. Markers on one chromosome were included simultaneously in a multilocus model and least angle regression was used to select the most potentially associated single-nucleotide polymorphisms (SNPs), whereas the markers on the other chromosomes were used to calculate kinship matrix as polygenic background control. The selected SNPs in multilocus model were further detected for their association with the trait by empirical Bayes and likelihood ratio test. We herein refer to this method as the pLARmEB (polygenic-background-control-based least angle regression plus empirical Bayes). Results from simulation studies showed that pLARmEB was more powerful in QTN detection and more accurate in QTN effect estimation, had less false positive rate and required less computing time than Bayesian hierarchical generalized linear model, efficient mixed model association (EMMA) and least angle regression plus empirical Bayes. pLARmEB, multilocus random-SNP-effect mixed linear model and fast multilocus random-SNP-effect EMMA methods had almost equal power of QTN detection in simulation experiments. However, only pLARmEB identified 48 previously reported genes for 7 flowering time-related traits in Arabidopsis thaliana.

  3. Electrophoretically mediated microanalysis of a nicotinamide adenine dinucleotide-dependent enzyme and its facile multiplexing using an active pixel sensor UV detector.

    PubMed

    Urban, Pawel L; Goodall, David M; Bergström, Edmund T; Bruce, Neil C

    2007-08-31

    An electrophoretically mediated microanalysis (EMMA) method has been developed for yeast alcohol dehydrogenase and quantification of reactant and product cofactors, NAD and NADH. The enzyme substrate ethanol (1% (v/v)) was added to the buffer (50 mM borate, pH 8.8). Results are presented for parallel capillary electrophoresis with a novel miniature UV area detector, with an active pixel sensor imaging an array of two or six parallel capillaries connected via a manifold to a single output capillary in a commercial CE instrument, allowing conversions with five different yeast alcohol dehydrogenase concentrations to be quantified in a single experiment.

  4. Recent Developments at the Accelerator Laboratory in Jyvaeskylae

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Trzaska, Wladyslaw Henryk

    Recent developments at the Accelerator Laboratory in Jyvaeskylae are described. In addition to the existing K = 130 a new cyclotron has been added. It is capable of producing of high current proton and deuteron beams at 30 and 15 MeV correspondingly. It should be fully operational in 2010. A new development in Jyvaeskylae is the growing commitment to astroparticle physics. Jyvaeskylae took the main scientific responsibility for a new cosmic-ray experiment EMMA and has joined the LAGUNA project working on the design of the next generation of very large volume detectors for underground observatories.

  5. Outstanding Student Paper Awards

    NASA Astrophysics Data System (ADS)

    2004-04-01

    The following members in the Space Physics & Aeronomy Section received Outstanding Student Paper Awards at the 2003 AGU Fall Meeting in San Francisco, California. Arve Aksnes; Aroh Barjatya; Jacob Bortnik; Amir Caspi; Ruben Delgado; Galen Fowler; Paul G. Hanlon; Sid Henderson; Tara B. Hiebert; Chia-Lin Huang; Steven P. Joy; Eun-Hwa Kim; Colby Lemon; Yingjuan Ma; Elizabeth A. MacDonald; Jaco Minnie; Mitsuo Oka; Yoshitaka Okazaki; Erin J. Rigler; Ina P. Robertson; Patrick A. Roddy; Sang-Il Roh; Albert Y. Shih; Christopher Smithtro; Emma Spanswick; Maria Spasojevic; Hiroki Tanaka; Linghua Wang; Deirdre E. Wendel; Jichun Zhang>

  6. Outstanding Student Paper Awards

    NASA Astrophysics Data System (ADS)

    2003-01-01

    The following members in the Space Physics & Aeronomy Section received Outstanding Student Paper Awards at the 2003 AGU Fall Meeting in San Francisco, California. Arve Aksnes; Aroh Barjatya; Jacob Bortnik; Amir Caspi; Ruben Delgado; Galen Fowler; Paul G. Hanlon; Sid Henderson; Tara B. Hiebert; Chia-Lin Huang; Steven P. Joy; Eun-Hwa Kim; Colby Lemon; Yingjuan Ma; Elizabeth A. MacDonald; Jaco Minnie; Mitsuo Oka; Yoshitaka Okazaki; Erin J. Rigler; Ina P. Robertson; Patrick A. Roddy; Sang-Il Roh; Albert Y. Shih; Christopher Smithtro; Emma Spanswick; Maria Spasojevic; Hiroki Tanaka; Linghua Wang; Deirdre E. Wendel; Jichun Zhang>

  7. Stennis group receives NESC award

    NASA Image and Video Library

    2009-04-14

    The NASA Engineering & Safety Center recently presented its Group Achievement Award to a Stennis team in recognition of technical excellence in evaluating the operational anomalies and reliability improvements associated with the space shuttle engine cut-off system. Stennis employees receiving the award were: (standing, l to r) Freddie Douglas (NASA), George Drouant (Jacobs Technology Inc.), Fred Abell (Jacobs), Robert Drackett (Jacobs) and Mike Smiles (NASA); (seated, l to r): Binh Nguyen (Jacobs), Stennis Director Gene Goldman and Joseph Lacker (NASA). Phillip Hebert of NASA is not pictured.

  8. The enduring legacy of the “constant-field equation” in membrane ion transport

    PubMed Central

    2017-01-01

    In 1943, David Goldman published a seminal paper in The Journal of General Physiology that reported a concise expression for the membrane current as a function of ion concentrations and voltage. This body of work was, and still is, the theoretical pillar used to interpret the relationship between a cell’s membrane potential and its external and/or internal ionic composition. Here, we describe from an historical perspective the theory underlying the constant-field equation and its application to membrane ion transport. PMID:28931632

  9. Information Strategy Plan

    DTIC Science & Technology

    1992-01-01

    47 OROO I SAOoflC P- K -- 8-3 NSWC DD/TR-92/47 b~2b, Ima~I I MUCT 0 Ii I 21AW Lp MAin B-3, NSWCDD/TR-92/47 APPENDIX C CLUSTERED CRUD MATRIX The CRUD...Berkey (D2); R.D. Wiseman and R.M. Pollock (E); W. Innis (G); LC. Loeffler ( K ); H.O. Williams, B.S. Goldman and L.W. Dabbs (M); W.J. Ferreira (P...Model................. B -1 C Clustered CRUD Matrix ...................................... C-1 D Data Flow Diagrams

  10. Modeling the action-potential-sensitive nonlinear-optical response of myelinated nerve fibers and short-term memory

    NASA Astrophysics Data System (ADS)

    Shneider, M. N.; Voronin, A. A.; Zheltikov, A. M.

    2011-11-01

    The Goldman-Albus treatment of the action-potential dynamics is combined with a phenomenological description of molecular hyperpolarizabilities into a closed-form model of the action-potential-sensitive second-harmonic response of myelinated nerve fibers with nodes of Ranvier. This response is shown to be sensitive to nerve demyelination, thus enabling an optical diagnosis of various demyelinating diseases, including multiple sclerosis. The model is applied to examine the nonlinear-optical response of a three-neuron reverberating circuit—the basic element of short-term memory.

  11. Stennis group receives NESC award

    NASA Technical Reports Server (NTRS)

    2009-01-01

    The NASA Engineering & Safety Center recently presented its Group Achievement Award to a Stennis team in recognition of technical excellence in evaluating the operational anomalies and reliability improvements associated with the space shuttle engine cut-off system. Stennis employees receiving the award were: (standing, l to r) Freddie Douglas (NASA), George Drouant (Jacobs Technology Inc.), Fred Abell (Jacobs), Robert Drackett (Jacobs) and Mike Smiles (NASA); (seated, l to r): Binh Nguyen (Jacobs), Stennis Director Gene Goldman and Joseph Lacker (NASA). Phillip Hebert of NASA is not pictured.

  12. The Role of Sentence Position, Allomorph, and Morpheme Type on Accurate Use of s-Related Morphemes by Children Who Are Hard of Hearing

    PubMed Central

    Koehlinger, Keegan; Oleson, Jacob; McCreery, Ryan; Moeller, Mary Pat

    2015-01-01

    Purpose Production accuracy of s-related morphemes was examined in 3-year-olds with mild-to-severe hearing loss, focusing on perceptibility, articulation, and input frequency. Method Morphemes with /s/, /z/, and /ɪz/ as allomorphs (plural, possessive, third-person singular –s, and auxiliary and copula “is”) were analyzed from language samples gathered from 51 children (ages: 2;10 [years;months] to 3;8) who are hard of hearing (HH), all of whom used amplification. Articulation was assessed via the Goldman-Fristoe Test of Articulation–Second Edition, and monomorphemic word final /s/ and /z/ production. Hearing was measured via better ear pure tone average, unaided Speech Intelligibility Index, and aided sensation level of speech at 4 kHz. Results Unlike results reported for children with normal hearing, the group of children who are HH correctly produced the /ɪz/ allomorph more than /s/ and /z/ allomorphs. Relative accuracy levels for morphemes and sentence positions paralleled those of children with normal hearing. The 4-kHz sensation level scores (but not the better ear pure tone average or Speech Intelligibility Index), the Goldman-Fristoe Test of Articulation–Second Edition, and word final s/z use all predicted accuracy. Conclusions Both better hearing and higher articulation scores are associated with improved morpheme production, and better aided audibility in the high frequencies and word final production of s/z are particularly critical for morpheme acquisition in children who are HH. PMID:25650750

  13. A teoria da percolação aplicada às galáxias aneladas peculiares

    NASA Astrophysics Data System (ADS)

    Poppe, P. C. R.; Martin, V. A. F.; de Medeiros, N. G. F.; Faúndez-Abans, M.; Oliveira-Abans, M.

    2003-08-01

    Formulado no final da década de 50, o modelo de percolação concentra-se em descrever o meio poroso, que será visto neste trabalho como uma rede de canais aleatórios, por onde escoa um fluido determinístico. Se o número de canais for suficientemente grande, então eles estarão ligados e o meio se tornará permeável à passagem do fluido. Neste caso, dizemos que houve a percolação do fluido. Reformulando o modelo acima, podemos escrever um código particularmente adaptado para simulações em Galáxias, onde iremos supor que os canais formam um reticulado, e que cada sítio da rede representa um poro que será interpretado como uma região ativa de formação estelar. Para cada elo teremos um pequeno canal ligando dois sítios vizinhos, que poderá, após um tempo "t", induzir ou não a formação de uma região ativa no poro vizinho. Para simular a passagem desta região ativa através dos poros, diremos que um elo está aberto com probabilidade p e fechado com probabilidade 1-p. Dessa forma, passamos a imaginar configurações de elos abertos e fechados, onde cada configuração ocorre com uma certa probabilidade, dada por p|A|(1-p)|F|, onde |A| é o número de elos abertos e |F| o número de elos fechados da configuração. A expressão anterior só tem importância física se |A| e |F| forem ambos finitos, pois, caso contrário, a probabilidade de ocorrência de uma dada configuração será sempre nula. Neste trabalho, foram considerados dados cinemáticos publicados na literatura bem como aqueles obtidos pelos autores a partir de observações fotométricas realizadas no Observatório de Las Campanãs, em 1994, para a Galáxia Anelada Peculiar HRG 03401. Mostraremos que para certos valores de p, situados entre 0,5 e 0,6, os clusters assim formados irão simular, de maneira coerente, o referido objeto.

  14. NASA Day at the Capitol

    NASA Image and Video Library

    2009-02-19

    Stennis Space Center leaders and guests visit with Mississippi Senate members in chambers during NASA Day at the Capitol events in Jackson on Feb. 19. Standing at the Senate podium (rear) is Mississippi Lt. Gov. Phil Bryant. Standing at the lectern below are (l to r): Sen. David Baria, D-Bay St. Louis; Partners for Stennis Chair Clay Wagner; NASA Shared Services Center Director Rick Arbuthnot; astronaut Rex Walheim; Stennis Space Center Director Gene Goldman; President Pro Tempore Billy Hewes, R-Gulfport; Sen. Ezell Lee, D-Picayune; and Sen. Tommy Gollott, R-Biloxi.

  15. Ancient Earth, Alien Earths Event

    NASA Image and Video Library

    2014-08-20

    Dr. Shawn Domagal-Goldman, Research Space Scientist, NASA Goddard Space Flight Center, speaks on a panel at the “Ancient Earth, Alien Earths” Event at NASA Headquarters in Washington, DC Wednesday, August 20, 2014. The event was sponsored by NASA, the National Science Foundation (NSF), and the Smithsonian Institution and was moderated by Dr. David H. Grinspoon, Senior Scientist at the Planetary Science Institute. Six scientists discussed how research on early Earth could help guide our search for habitable planets orbiting other stars. Photo Credit: (NASA/Aubrey Gemignani)

  16. [From Einstein's Quantum Theory to modern laser therapy. The history of lasers in dermatology and aesthetic medicine].

    PubMed

    Graudenz, K; Raulin, C

    2003-07-01

    Laser technology has considerably expanded therapeutic modalities in dermatology and aesthetic medicine. In addition, lasers have broadened the spectrum of diagnostic and therapeutic options in many other medical fields. Dermatologists, especially Dr. Leon Goldman, played an important role in the evolution and use of medical lasers. There was a long way from the concept of stimulated emission as the fundamental idea of laser technology by Albert Einstein in 1917 to the practical use of the laser today. We review the development of laser technology from the early days through the latest advances.

  17. Gov. Barbour views test firing

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Steam billows from an RS-68 rocket engine test at the B Test Stand at Stennis Space Center on June 2. The test was viewed by Mississippi Gov. Haley Barbour (third from left) and his wife, Marsha, who spent the afternoon at the NASA rocket engine testing center. The governor was joined at the RS-68 test by (l to r) Charles Scales, NASA associate deputy administrator; Jeffrey Wright, Pratt & Whitney Rocketdyne site director at Stennis; Gene Goldman, Stennis director; and Jack Forsythe, NASA assistant administrator for the Office of Security and Program Protection.

  18. Gov. Barbour views test firing

    NASA Image and Video Library

    2009-06-02

    Steam billows from an RS-68 rocket engine test at the B Test Stand at Stennis Space Center on June 2. The test was viewed by Mississippi Gov. Haley Barbour (third from left) and his wife, Marsha, who spent the afternoon at the NASA rocket engine testing center. The governor was joined at the RS-68 test by (l to r) Charles Scales, NASA associate deputy administrator; Jeffrey Wright, Pratt & Whitney Rocketdyne site director at Stennis; Gene Goldman, Stennis director; and Jack Forsythe, NASA assistant administrator for the Office of Security and Program Protection.

  19. Leaders break ground for INFINITY

    NASA Image and Video Library

    2008-11-20

    Community leaders from Mississippi and Louisiana break ground for the new INFINITY at NASA Stennis Space Center facility during a Nov. 20 ceremony. Groundbreaking participants included (l to r): Gottfried Construction representative John Smith, Mississippi Highway Commissioner Wayne Brown, INFINITY board member and Apollo 13 astronaut Fred Haise, Stennis Director Gene Goldman, Studio South representative David Hardy, Leo Seal Jr. family representative Virginia Wagner, Hancock Bank President George Schloegel, Mississippi Rep. J.P. Compretta, Mississippi Band of Choctaw Indians representative Charlie Benn and Louisiana Sen. A.G. Crowe.

  20. Automatic Generation of Issue Maps: Structured, Interactive Outputs for Complex Information Needs

    DTIC Science & Technology

    2012-09-01

    much can result in behaviour similar to the shortest-path chains. 24 Ronald Goldman Neil Lewis Judge Lance Ito 1 1 1 1 1 0 0 0 1 1 1 1 1 1 1 jury...Connecting the Dots has also been explored in non-textual domains. The authors of [ Heath et al., 2010] propose building graphs, called Image Webs, to...could imagine a metro map summarizing a dataset of medical records. 2. Images: In [ Heath et al., 2010], Heath et al build graphs called Image Webs to rep

  1. Evaluation of procoagulant tissue factor expression in canine hemangiosarcoma cell lines.

    PubMed

    Witter, Lauren E; Gruber, Erika J; Lean, Fabian Z X; Stokol, Tracy

    2017-01-01

    OBJECTIVE To evaluate expression of procoagulant tissue factor (TF) by canine hemangiosarcoma cells in vitro. SAMPLES 4 canine hemangiosarcoma cell lines (SB-HSA [mouse-passaged cutaneous tumor], Emma [primary metastatic brain tumor], and Frog and Dal-1 [primary splenic tumors]) and 1 nonneoplastic canine endothelial cell line (CnAoEC). PROCEDURES TF mRNA and TF antigen expression were evaluated by quantitative real-time PCR assay and flow cytometry, respectively. Thrombin generation was measured in canine plasma and in coagulation factor-replete or specific coagulation factor-deficient human plasma by calibrated automated thrombography. Corn trypsin inhibitor and annexin V were used to examine contributions of contact activation and membrane-bound phosphatidylserine, respectively, to thrombin generation. RESULTS All cell lines expressed TF mRNA and antigen, with significantly greater expression of both products in SB-HSA and Emma cells than in CnAoEC. A greater percentage of SB-HSA cells expressed TF antigen, compared with other hemangiosarcoma cell lines. All hemangiosarcoma cell lines generated significantly more thrombin than did CnAoEC in canine or factor-replete human plasma. Thrombin generation induced by SB-HSA cells was significantly lower in factor VII-deficient plasma than in factor-replete plasma and was abolished in factor X-deficient plasma; residual thrombin generation in factor VII-deficient plasma was abolished by incubation of cells with annexin V. Thrombin generation by SB-HSA cells was unaffected by the addition of corn trypsin inhibitor. CONCLUSIONS AND CLINICAL RELEVANCE Hemangiosarcoma cell lines expressed procoagulant TF in vitro. Further research is needed to determine whether TF can be used as a biomarker for hemostatic dysfunction in dogs with hemangiosarcoma.

  2. Evaluation of procoagulant tissue factor expression in canine hemangiosarcoma cell lines

    PubMed Central

    Witter, Lauren E.; Gruber, Erika J.; Lean, Fabian Z. X.; Stokol, Tracy

    2017-01-01

    OBJECTIVE To evaluate expression of procoagulant tissue factor (TF) by canine hemangiosarcoma cells in vitro. SAMPLES 4 canine hemangiosarcoma cell lines (SB-HSA [mouse-passaged cutaneous tumor], Emma [primary metastatic brain tumor], and Frog and Dal-1 [primary splenic tumors]) and 1 nonneoplastic canine endothelial cell line (CnAoEC). PROCEDURES TF mRNA and TF antigen expression were evaluated by quantitative real-time PCR assay and flow cytometry, respectively. Thrombin generation was measured in canine plasma and in coagulation factor–replete or specific coagulation factor–deficient human plasma by calibrated automated thrombography. Corn trypsin inhibitor and annexin V were used to examine contributions of contact activation and membrane-bound phosphatidylserine, respectively, to thrombin generation. RESULTS All cell lines expressed TF mRNA and antigen, with significantly greater expression of both products in SB-HSA and Emma cells than in CnAoEC. A greater percentage of SB-HSA cells expressed TF antigen, compared with other hemangiosarcoma cell lines. All hemangiosarcoma cell lines generated significantly more thrombin than did CnAoEC in canine or factor-replete human plasma. Thrombin generation induced by SB-HSA cells was significantly lower in factor VII-deficient plasma than in factor-replete plasma and was abolished in factor X–deficient plasma; residual thrombin generation in FVII-deficient plasma was abolished by incubation of cells with annexin V. Thrombin generation by SB-HSA cells was unaffected by the addition of corn trypsin inhibitor. CONCLUSIONS AND CLINICAL RELEVANCE Hemangiosarcoma cell lines expressed procoagulant TF in vitro. Further research is needed to determine whether TF can be used as a biomarker for hemostatic dysfunction in dogs with hemangiosarcoma. PMID:28029283

  3. Jupiter's Dynamic Atmosphere

    NASA Image and Video Library

    2018-05-09

    This image captures the dynamic nature of Jupiter's northern temperate belt. The view reveals a white, oval-shaped anticyclonic storm called WS-4. NASA's Juno spacecraft took this color-enhanced image on April 1 at 2:38 a.m. PST (5:38 a.m. EST) during its 12th close flyby of the gas giant planet. At the time, the spacecraft was 4,087 miles (6,577 kilometers) from the tops of Jupiter's clouds at 35.6 degrees north latitude. This image was created by citizen scientist Emma Walimaki using data from the JunoCam imager on NASA's Juno spacecraft. https://photojournal.jpl.nasa.gov/catalog/PIA22420

  4. The complete mitochondrial genome of the black field cricket, Teleogryllus oceanicus.

    PubMed

    Zhou, Jiu-Xuan; Jia, Yong-Chao; Yang, Xue-Chao; Li, Qiang

    2017-03-01

    In this study, the complete mitochondrial genome sequence of the black field cricket, Teleogryllus oceanicus, with the total length of 15 660 bp is determined for the first time. This mitochondrial genome harbors 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNA), two ribosomal RNA genes (rRNA), and one control region (D-loop). The overall base composition is A (40.44%), C (17.12%), G (9.84%), and T (32.60%), so the slight A-T bias (73.04%) was detected. Phylogenetic analysis showed that T. oceanicus is closely related to T. emma that is also a member of the genus Teleogryllus.

  5. A resolution calling on Brazil to comply with the requirements of the Convention on the Civil Aspects of International Child Abduction and to assist in the safe return of Sean Goldman to his father, David Goldman.

    THOMAS, 111th Congress

    Sen. Lautenberg, Frank R. [D-NJ

    2009-02-11

    Senate - 03/24/2009 Resolution agreed to in Senate with an amendment and an amendment to the Title and an amended preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  6. Concept for estimating mitochondrial DNA haplogroups using a maximum likelihood approach (EMMA)☆

    PubMed Central

    Röck, Alexander W.; Dür, Arne; van Oven, Mannis; Parson, Walther

    2013-01-01

    The assignment of haplogroups to mitochondrial DNA haplotypes contributes substantial value for quality control, not only in forensic genetics but also in population and medical genetics. The availability of Phylotree, a widely accepted phylogenetic tree of human mitochondrial DNA lineages, led to the development of several (semi-)automated software solutions for haplogrouping. However, currently existing haplogrouping tools only make use of haplogroup-defining mutations, whereas private mutations (beyond the haplogroup level) can be additionally informative allowing for enhanced haplogroup assignment. This is especially relevant in the case of (partial) control region sequences, which are mainly used in forensics. The present study makes three major contributions toward a more reliable, semi-automated estimation of mitochondrial haplogroups. First, a quality-controlled database consisting of 14,990 full mtGenomes downloaded from GenBank was compiled. Together with Phylotree, these mtGenomes serve as a reference database for haplogroup estimates. Second, the concept of fluctuation rates, i.e. a maximum likelihood estimation of the stability of mutations based on 19,171 full control region haplotypes for which raw lane data is available, is presented. Finally, an algorithm for estimating the haplogroup of an mtDNA sequence based on the combined database of full mtGenomes and Phylotree, which also incorporates the empirically determined fluctuation rates, is brought forward. On the basis of examples from the literature and EMPOP, the algorithm is not only validated, but both the strength of this approach and its utility for quality control of mitochondrial haplotypes is also demonstrated. PMID:23948335

  7. Deglaciation and postglacial treeline fluctuation in the northern San Juan Mountains, Colorado

    USGS Publications Warehouse

    Carrara, Paul E.

    2011-01-01

    The San Juan Mountains of southwestern Colorado contain numerous lakes and bogs at and above treeline. In June 1978, Lake Emma, a tarn above present-day treeline, was suddenly drained by the collapse of underground mine workings. This study was initiated because the draining exposed a well-preserved archive of subfossil coniferous wood fragments that provided a unique opportunity to further our understanding of the paleoclimatic history of this region. These paleoclimatic studies-coniferous macrofossil identification in conjunction with radiocarbon dating, deuterium analysis of the dated conifer fragments, as well as pollen and fossil insect analyses-yielded new information regarding Holocene climate and accompanying treeline changes in the northern San Juan Mountains. This report synthesizes previously published reports by the author and other investigators, and unpublished information of the author bearing on late Pleistocene and Holocene treeline and climate in this region. Retreat of the glacier that occupied the upper Animas River valley from its Pinedale terminal position began about 19.4 + or - 1.5 10Be thousands of years ago and was essentially complete by about 12.3 + or - 1.0 10Be thousands of years ago. Two sets of late Pleistocene cirque moraines were identified in the northern San Juan Mountains. The older set is widespread and probably correlates with the Younger Dryas (11,000-10,000 radiocarbon years before present; 12,800-11,500 calendar years). The younger set is found only in the Grenadier Range and represents remnant glacier ice lying in well-shaded niches in a mountain range undergoing rapid deglaciation. A snowbank at the northern base of this range appears to be fronted by a Little Ice Age moraine. Soon after deglaciation the average July temperature is estimated to have been about 5°C cooler and timberline about 650 meters lower than at present. However, timberline (and treeline) responded rapidly to the postglacial warming and reached

  8. Comparison of estimation accuracy of body density between different hydrostatics weighing methods without head submersion.

    PubMed

    Demura, Shinichi; Sato, Susumu; Nakada, Masakatsu; Minami, Masaki; Kitabayashi, Tamotsu

    2003-07-01

    This study compared the accuracy of body density (Db) estimation methods using hydrostatic weighing without complete head submersion (HW(withoutHS)) of Donnelly et al. (1988) and Donnelly and Sintek (1984) as referenced to Goldman and Buskirk's approach (1961). Donnelly et al.'s method estimates Db from a regression equation using HW(withoutHS), moreover, Donnelly and Sintek's method estimates it from HW(withoutHS) and head anthropometric variables. Fifteen Japanese males (173.8+/-4.5 cm, 63.6+/-5.4 kg, 21.2+/-2.8 years) and fifteen females (161.4+/-5.4 cm, 53.8+/-4.8 kg, 21.0+/-1.4 years) participated in this study. All the subjects were measured for head length, width and HWs under the two conditions of with and without head submersion. In order to examine the consistency of estimation values of Db, the correlation coefficients between the estimation values and the reference (Goldman and Buskirk, 1961) were calculated. The standard errors of estimation (SEE) were calculated by regression analysis using a reference value as a dependent variable and estimation values as independent variables. In addition, the systematic errors of two estimation methods were investigated by the Bland-Altman technique (Bland and Altman, 1986). In the estimation, Donnelly and Sintek's equation showed a high relationship with the reference (r=0.960, p<0.01), but had more differences from the reference compared with Donnelly et al.'s equation. Further studies are needed to develop new prediction equations for Japanese considering sex and individual differences in head anthropometry.

  9. High-energy Nd:glass laser for oncology

    NASA Astrophysics Data System (ADS)

    Boutchenkov, Vyatcheslav A.; Utenkov, Boris I.; Zaitsev, V. K.; Bayanov, Valentin I.; Serebryakov, Victor A.

    1991-07-01

    The use of high energy solid state lasers for the treatment of human skin neoplasia was based on the experiments and clinic studies by Helsper and Goldman (1964), McGuff (1966). The heat of precise local volume is emitted due to the pulse laser radiation. The thermal effect results in the superficial necrosis of tissues with their integrity destruction, vascular repture accompanied by bloodstoke in some cases and by capillary embolism in others. Obvious tumour destruction is note only in case of high density irradiation. General tumour destruction depends on biological neoplasia features as well as the laser type.

  10. Metal-fluxes characterization at a catchment scale: Study of mixing processes and end-member analysis in the Meca River watershed (SW Spain)

    NASA Astrophysics Data System (ADS)

    Cánovas, C. R.; Macías, F.; Olías, M.; López, R. Pérez; Nieto, J. M.

    2017-07-01

    Fluxes of acidity and contaminants from acid mine drainage (AMD) sources to the receiving surface water bodies were studied in a mining-impacted watershed (Meca River, SW Spain) using a novel methodology based on the joint application of EMMA and MIX codes. The application of EMMA and elemental ratios allowed delimiting the end-members responsible for water quality variations at a catchment scale. The further application of MIX quantified the significant impact of AMD on the river quality; less than 10% of AMD relative contribution is enough to maintain acidic conditions during most of the year. The mixing model also provided information about the element mobility, distinguishing those elements with a quasi-conservative behavior (e.g., Cu, Zn, Al, Co or Ni) from those affected by mineral precipitation/dissolution (e.g., K, Si, Na, Sr, Ca, Fe, Pb, or As). Floods are the main driver of dissolved and, mainly particulate, contaminants in the catchment. Thus, the first rainfall events in November only accounted for 19% of the annual Meca flow but yielded between 26 and 43% of the net acidity and dissolved metal loads (mainly, Fe, As and Pb). Concerning particulate transport, around 332 tons of particulate Fe, 49 tons of Al, 0.79 tons of As and 0.37 tons of Pb were recorded during these first floods. The particulate As concentration can be up to 34 times higher than the dissolved one during floods and between 2 and 4 times higher for Fe, Pb and Cr. This integrated modeling approach could be a promising and useful tool to face future restoration plans in derelict mines worldwide. This approach would allow prioritizing remedial measures, achieving an environmental and cost-effective restoration of degraded areas.

  11. Dust in Rain During Drought: An Overlooked Pathway for Elemental Flux to Ecosystems

    NASA Astrophysics Data System (ADS)

    Ponette-González, A.; Collins, J. D., Jr.; Manuel, J. E.; Byers, T. A.; Glass, G. A.; Weathers, K. C.; Gill, T. E.

    2017-12-01

    Airborne dust has the potential to alter ecosystem productivity and biogeochemical cycles at local to global scales by enhancing atmospheric deposition of critical limiting nutrients and toxic pollutants. Suspended dust particles are delivered to ecosystems directly via dry deposition or in precipitation (wet deposition) by rainout and washout. Compared to dry deposition, dust removal by precipitation (dust-in-rain) is a seldom quantified yet potentially significant flux between the atmosphere and ecosystems. We quantified dust effects on the ionic and elemental composition of precipitation and on wet deposition rates at a National Atmospheric Deposition Program (NADP) monitoring site in west Texas during the extreme 2012 drought. Dust events were identified using meteorological data for stations within a 150-km radius buffer surrounding the NADP site. Data on the dissolved chemistry of weekly wet deposition samples and elemental analysis of the particulate fraction were analyzed. Calcium was the dominant dissolved ion in rainwater, comprising 61% of the total measured solute content during dust-in rain weeks. In the particulate fraction, Fe alone made up 81% of the elemental composition during dust-in-rain weeks. At this site, five dust-in-rain weeks delivered 19% of the annual water input (51 mm water). However, these weeks contributed 46-70% of the annual dissolved Ca2+, Mg2+, K+, Na+, PO43-, and Cl- flux and >55% of the particulate Fe, Ti, V, Ni, Rb, Ga, and Br flux. Sourcing analysis, conducted using an End-Member Mixing Algorithm (EMMA) on the particulate fraction identified Fe, Cu, Rb, and Sr end-members, representing 87% of the total elemental variance. In addition, EMMA showed that dust-in-rain weeks were more well mixed than other rainfall weeks. Preliminary findings for this west Texas site show that infrequent dust-in-rain events constitute an important but overlooked proportion of the elemental flux to ecosystems during severe drought.

  12. Perspective: POTUS Trump's Executive Orders - Implications for Immigrants and Health Care.

    PubMed

    Talamantes, Efrain; Aguilar-Gaxiola, Sergio

    2017-01-01

    The United States, under new executive orders proposed by its 45th president, may quickly lose its greatness in serving Emma Lazarus' untimely portrait of immigrants and refugees as " the tired, poor and huddled masses yearning to breathe free ." After years of progress in improving health care access to underserved populations, new executive orders threaten our nation's advancements in health equity. Within this perspective, we offer examples on how these actions may result in damaging impacts on patients, families, communities and the health care workforce. We add our voices to a myriad of national leaders who are advocating for the preservation of the Affordable Care Act (ACA) and the protection of immigrants, including Deferred Action for Childhood Arrivals (DACA).

  13. Lower-zone emphysema in young patients without α1-antitrypsin deficiency

    PubMed Central

    Martelli, Nestor A.; Goldman, Ernesto; Roncoroni, Aquiles J.

    1974-01-01

    Martelli, N. A., Goldman, E., and Roncoroni, A. J. (1974).Thorax, 29, 237-244. Lowerzone emphysema in young patients without α1-antitrypsin deficiency. Three young patients with radiographic pulmonary emphysema predominantly in the lower zones are reported. The clinical and physiological features were those observed in severe pulmonary emphysema. Predominance of the main lesions in the lower zones was confirmed in two cases by selective pulmonary angiography. One of the patients died and extensive panlobular emphysema was found at necropsy. Although the similarities between our patients and those with emphysema and α1-antitrypsin deficiency were remarkable, the latter condition was ruled out. Images PMID:4545502

  14. Eyeballing oscillators for pulsed Doppler radar

    NASA Astrophysics Data System (ADS)

    Goldman, S.

    1985-03-01

    The visibility of small targets to a Doppler radar system in the presence of large targets is limited by phase noise. Such limitations occur when an airborne radar searches the ground for a mobile vehicle. Under these conditions, the performance of the Doppler radar depends greatly on the specifications of its phased-locked oscillator. Goldman (1984) has discussed the steps required to evaluate the noise resulting from a pulsed Doppler radar system. In the present investigation, these techniques are applied in reverse to determine system specifications for oscillator noise. A 95-GHz pulsed Doppler radar system is used as an example of specifying system phase noise.

  15. The self-propulsion of a helix in granular matter

    NASA Astrophysics Data System (ADS)

    Valdes, Rogelio; Angeles, Veronica; de La Calleja, Elsa; Zenit, Roberto

    2017-11-01

    The effect of the shape of helicoidal on the displacement of magnetic robots in granular media is studied experimentally. We quantify the influences of three main parameters of the shape of the helicoidal swimmers: body diameter, step, and the angle. We compare the experimental measurements with an empirically modified resistive force theory prediction that accounts for the static friction coefficient of the particles of the granular material, leading to good agreement. Comparisons are also made with the granular resistive force theory proposed by Goldman and collaborators. We found an optimal helix angle to produce movement and determined a relationship between the swimmer size and speed.

  16. Reparo de aneurisma de artéria ilíaca roto em criança

    PubMed Central

    Hoshiko, Fernando Massaru; Zampieri, Elisa Helena Subtil; Dalio, Marcelo Bellini; Dezotti, Nei Rodrigues Alves; Joviliano, Edwaldo Edner

    2017-01-01

    Resumo Relatamos o caso de uma menina de 12 anos que deu entrada na unidade de emergência com quadro de abdome agudo hemorrágico, massa abdominal pulsátil e instabilidade hemodinâmica. Confirmado o diagnóstico de aneurisma roto de artéria ilíaca direita, foi realizada correção cirúrgica de emergência por reparo aberto com reconstrução extra-anatômica, utilizando enxerto sintético de fino calibre, compatível com a anatomia. O tratamento foi bem-sucedido e a criança apresentou evolução favorável em curto prazo.

  17. A new type of accelerator for charged particle cancer therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edgecock, Rob

    2013-04-19

    Non-scaling Fixed Field Alternating Gradient accelerators (ns-FFAGs) show great potential for the acceleration of protons and light ions for the treatment of certain cancers. They have unique features as they combine techniques from the existing types of accelerators, cyclotrons and synchrotrons, and hence look to have advantages over both for this application. However, these unique features meant that it was necessary to build one of these accelerators to show that it works and to undertake a detailed conceptual design of a medical machine. Both of these have now been done. This paper will describe the concepts of this type ofmore » accelerator, show results from the proof-of-principle machine (EMMA) and described the medical machine (PAMELA).« less

  18. Perspective: POTUS Trump’s Executive Orders – Implications for Immigrants and Health Care

    PubMed Central

    Talamantes, Efrain; Aguilar-Gaxiola, Sergio

    2017-01-01

    The United States, under new executive orders proposed by its 45th president, may quickly lose its greatness in serving Emma Lazarus’ untimely portrait of immigrants and refugees as “the tired, poor and huddled masses yearning to breathe free.” After years of progress in improving health care access to underserved populations, new executive orders threaten our nation’s advancements in health equity. Within this perspective, we offer examples on how these actions may result in damaging impacts on patients, families, communities and the health care workforce. We add our voices to a myriad of national leaders who are advocating for the preservation of the Affordable Care Act (ACA) and the protection of immigrants, including Deferred Action for Childhood Arrivals (DACA). PMID:28439182

  19. Speech sound articulation abilities of preschool-age children who stutter.

    PubMed

    Clark, Chagit E; Conture, Edward G; Walden, Tedra A; Lambert, Warren E

    2013-12-01

    The purpose of this study was to assess the association between speech sound articulation and childhood stuttering in a relatively large sample of preschool-age children who do and do not stutter, using the Goldman-Fristoe Test of Articulation-2 (GFTA-2; Goldman & Fristoe, 2000). Participants included 277 preschool-age children who do (CWS; n=128, 101 males) and do not stutter (CWNS; n=149, 76 males). Generalized estimating equations (GEE) were performed to assess between-group (CWS versus CWNS) differences on the GFTA-2. Additionally, within-group correlations were performed to explore the relation between CWS' speech sound articulation abilities and their stuttering frequency and severity, as well as their sound prolongation index (SPI; Schwartz & Conture, 1988). No significant differences were found between the articulation scores of preschool-age CWS and CWNS. However, there was a small gender effect for the 5-year-old age group, with girls generally exhibiting better articulation scores than boys. Additional findings indicated no relation between CWS' speech sound articulation abilities and their stuttering frequency, severity, or SPI. Findings suggest no apparent association between speech sound articulation-as measured by one standardized assessment (GFTA-2)-and childhood stuttering for this sample of preschool-age children (N=277). After reading this article, the reader will be able to: (1) discuss salient issues in the articulation literature relative to children who stutter; (2) compare/contrast the present study's methodologies and main findings to those of previous studies that investigated the association between childhood stuttering and speech sound articulation; (3) identify future research needs relative to the association between childhood stuttering and speech sound development; (4) replicate the present study's methodology to expand this body of knowledge. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. On the nature of liquid junction and membrane potentials.

    PubMed

    Perram, John W; Stiles, Peter J

    2006-09-28

    Whenever a spatially inhomogeneous electrolyte, composed of ions with different mobilities, is allowed to diffuse, charge separation and an electric potential difference is created. Such potential differences across very thin membranes (e.g. biomembranes) are often interpreted using the steady state Goldman equation, which is usually derived by assuming a spatially constant electric field. Through the fundamental Poisson equation of electrostatics, this implies the absence of free charge density that must provide the source of any such field. A similarly paradoxical situation is encountered for thick membranes (e.g. in ion-selective electrodes) for which the diffusion potential is normally interpreted using the Henderson equation. Standard derivations of the Henderson equation appeal to local electroneutrality, which is also incompatible with sources of electric fields, as these require separated charges. We analyse self-consistent solutions of the Nernst-Planck-Poisson equations for a 1 : 1-univalent electrolyte to show that the Goldman and Henderson steady-state membrane potentials are artefacts of extraneous charges created in the reservoirs of electrolyte solution on either side of the membrane, due to the unphysical nature of the usual (Dirichlet) boundary conditions assumed to apply at the membrane-electrolyte interfaces. We also show, with the aid of numerical simulations, that a transient electric potential difference develops in any confined, but initially non-uniform, electrolyte solution. This potential difference ultimately decays to zero in the real steady state of the electrolyte, which corresponds to thermodynamic equilibrium. We explain the surprising fact that such transient potential differences are well described by the Henderson equation by using a computer algebra system to extend previous steady-state singular perturbation theories to the time-dependent case. Our work therefore accounts for the success of the Henderson equation in analysing

  1. Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex

    PubMed Central

    Yang, Yang; Paspalas, Constantinos D.; Jin, Lu E.; Picciotto, Marina R.; Arnsten, Amy F. T.; Wang, Min

    2013-01-01

    The cognitive function of the highly evolved dorsolateral prefrontal cortex (dlPFC) is greatly influenced by arousal state, and is gravely afflicted in disorders such as schizophrenia, where there are genetic insults in α7 nicotinic acetylcholine receptors (α7-nAChRs). A recent behavioral study indicates that ACh depletion from dlPFC markedly impairs working memory [Croxson PL, Kyriazis DA, Baxter MG (2011) Nat Neurosci 14(12):1510–1512]; however, little is known about how α7-nAChRs influence dlPFC cognitive circuits. Goldman-Rakic [Goldman-Rakic (1995) Neuron 14(3):477–485] discovered the circuit basis for working memory, whereby dlPFC pyramidal cells excite each other through glutamatergic NMDA receptor synapses to generate persistent network firing in the absence of sensory stimulation. Here we explore α7-nAChR localization and actions in primate dlPFC and find that they are enriched in glutamate network synapses, where they are essential for dlPFC persistent firing, with permissive effects on NMDA receptor actions. Blockade of α7-nAChRs markedly reduced, whereas low-dose stimulation selectively enhanced, neuronal representations of visual space. These findings in dlPFC contrast with the primary visual cortex, where nAChR blockade had no effect on neuronal firing [Herrero JL, et al. (2008) Nature 454(7208):1110–1114]. We additionally show that α7-nAChR stimulation is needed for NMDA actions, suggesting that it is key for the engagement of dlPFC circuits. As ACh is released in cortex during waking but not during deep sleep, these findings may explain how ACh shapes differing mental states during wakefulness vs. sleep. The results also explain why genetic insults to α7-nAChR would profoundly disrupt cognitive experience in patients with schizophrenia. PMID:23818597

  2. AJ26 rocket engine testing news briefing

    NASA Technical Reports Server (NTRS)

    2010-01-01

    NASA's John C. Stennis Space Center Director Gene Goldman (center) stands in front of a 'pathfinder' rocket engine with Orbital Sciences Corp. President and Chief Operating Officer J.R. Thompson (left) and Aerojet President Scott Seymour during a Feb. 24 news briefing at the south Mississippi facility. The leaders appeared together to announce a partnership for testing Aerojet AJ26 rocket engines at Stennis. The engines will be used to power Orbital's Taurus II space vehicles to provide commercial cargo transportation missions to the International Space Station for NASA. During the event, the Stennis partnership with Orbital was cited as an example of the new direction of NASA to work with commercial interests for space travel and transport.

  3. A new species of nectar-feeding bat, genus Lonchophylla, from western Colombia and western Ecuador (Mammalia: Chiroptera: Phyllostomidae)

    USGS Publications Warehouse

    Woodman, N.

    2007-01-01

    The twelve recognized species of nectar-feeding bats of the genus Lonchophylla occur in low- and middle-elevation, humid, Neotropical forests. Morphological and morphometrical analyses of specimens formerly lumped with Lonchophylla mordax O. Thomas (1903) support recognition of Lonchophylla concava Goldman (1914) as a separate species and reveal a third species from the western Pacific lowlands of Colombia and Ecuador that I describe herein as Lonchophylla jornicata. This new species is morphologically similar to Lonchophylla concava but is distinctively larger than that species. Tests for sexual dimorphism within these and other species of Lonchophyllini suggest a tendency for females to have slightly longer, narrower skulls, higher coronoid processes of the mandible, and longer forearms than males.

  4. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.

    PubMed

    Himes, Blanca E; Sheppard, Keith; Berndt, Annerose; Leme, Adriana S; Myers, Rachel A; Gignoux, Christopher R; Levin, Albert M; Gauderman, W James; Yang, James J; Mathias, Rasika A; Romieu, Isabelle; Torgerson, Dara G; Roth, Lindsey A; Huntsman, Scott; Eng, Celeste; Klanderman, Barbara; Ziniti, John; Senter-Sylvia, Jody; Szefler, Stanley J; Lemanske, Robert F; Zeiger, Robert S; Strunk, Robert C; Martinez, Fernando D; Boushey, Homer; Chinchilli, Vernon M; Israel, Elliot; Mauger, David; Koppelman, Gerard H; Postma, Dirkje S; Nieuwenhuis, Maartje A E; Vonk, Judith M; Lima, John J; Irvin, Charles G; Peters, Stephen P; Kubo, Michiaki; Tamari, Mayumi; Nakamura, Yusuke; Litonjua, Augusto A; Tantisira, Kelan G; Raby, Benjamin A; Bleecker, Eugene R; Meyers, Deborah A; London, Stephanie J; Barnes, Kathleen C; Gilliland, Frank D; Williams, L Keoki; Burchard, Esteban G; Nicolae, Dan L; Ober, Carole; DeMeo, Dawn L; Silverman, Edwin K; Paigen, Beverly; Churchill, Gary; Shapiro, Steve D; Weiss, Scott T

    2013-01-01

    Asthma is a common chronic respiratory disease characterized by airway hyperresponsiveness (AHR). The genetics of asthma have been widely studied in mouse and human, and homologous genomic regions have been associated with mouse AHR and human asthma-related phenotypes. Our goal was to identify asthma-related genes by integrating AHR associations in mouse with human genome-wide association study (GWAS) data. We used Efficient Mixed Model Association (EMMA) analysis to conduct a GWAS of baseline AHR measures from males and females of 31 mouse strains. Genes near or containing SNPs with EMMA p-values <0.001 were selected for further study in human GWAS. The results of the previously reported EVE consortium asthma GWAS meta-analysis consisting of 12,958 diverse North American subjects from 9 study centers were used to select a subset of homologous genes with evidence of association with asthma in humans. Following validation attempts in three human asthma GWAS (i.e., Sepracor/LOCCS/LODO/Illumina, GABRIEL, DAG) and two human AHR GWAS (i.e., SHARP, DAG), the Kv channel interacting protein 4 (KCNIP4) gene was identified as nominally associated with both asthma and AHR at a gene- and SNP-level. In EVE, the smallest KCNIP4 association was at rs6833065 (P-value 2.9e-04), while the strongest associations for Sepracor/LOCCS/LODO/Illumina, GABRIEL, DAG were 1.5e-03, 1.0e-03, 3.1e-03 at rs7664617, rs4697177, rs4696975, respectively. At a SNP level, the strongest association across all asthma GWAS was at rs4697177 (P-value 1.1e-04). The smallest P-values for association with AHR were 2.3e-03 at rs11947661 in SHARP and 2.1e-03 at rs402802 in DAG. Functional studies are required to validate the potential involvement of KCNIP4 in modulating asthma susceptibility and/or AHR. Our results suggest that a useful approach to identify genes associated with human asthma is to leverage mouse AHR association data.

  5. Testing the usefulness of 222Rn to complement conventional hydrochemical data to trace groundwater provenance in complex multi-layered aquifers. Application to the Úbeda aquifer system (Jaén, SE Spain).

    PubMed

    Ortega, L; Manzano, M; Rodríguez-Arévalo, J

    2017-12-01

    The Úbeda aquifer system is a multi-layered aquifer intensively exploited for irrigation. It covers 1100km 2 and consists of piled up sedimentary aquifer and aquitard layers from Triassic sandstones and clays at the bottom, to Jurassic carbonates (main exploited layer) in the middle, and Miocene sandstones and marls at the top. Flow network modification by intense exploitation and the existence of deep faults favour vertical mixing of waters from different layers and with distinct chemical composition. This induces quality loss and fosters risk of quantity restrictions. To support future groundwater abstraction management, a hydrogeochemical (major and some minor solutes) and isotopic ( 222 Rn) study was performed to identify the chemical signatures of the different layers and their mixing proportions in mixed samples. The study of 134 groundwater samples allowed a preliminary identification of hydrochemical signatures and mixtures, but the existence of reducing conditions in the most exploited sector prevents the utility of sulphate as a tracer of Triassic groundwater in the Jurassic boreholes. The potential of 222 Rn to establish isotopic signatures and to trace groundwater provenance in mixtures was tested. 222 Rn was measured in 48 samples from springs and boreholes in most aquifer layers. At first, clear correlations were observed between 222 Rn, Cl and SO 4 in groundwater. Afterwards, very good correlations were observed between 222 Rn and the chemical facies of the different layers established with End Member Mixing Analysis (EMMA). Using 222 Rn as part of the signatures, EMMA helped to identify end-member samples, and to quantify the mixing proportions of water from the Triassic and the Deep Miocene layers in groundwater pumped by deep agricultural wells screened in the Jurassic. The incorporation of 222 Rn to the study also allowed identifying the impact of irrigation returns through the association of moderate NO 3 , Cl, and Br contents with very low 222

  6. Hydrostratigraphic and structural controls on streamflow generation in the Chuska Mountains, Navajo Nation, AZ/NM

    NASA Astrophysics Data System (ADS)

    Tsinnajinnie, L.; Frisbee, M. D.; Wilson, J. L.

    2017-12-01

    A conceptual model of hydrostratigraphic and structural influences on 3D streamflow generation processes is tested in the Whiskey Creek watershed located in the Chuska Mountains of the Navajo Nation along the northern NM/AZ border. The role of hydrostratigraphy and structure in groundwater processes has been well studied. However, influences of heterogeneity due to geologic structure and stratigraphy of mountain blocks on 3D streamflow generation has received less attention. Three-dimensional flow in mountainous watersheds, such as Saguache Creek (CO) and Rio Hondo (NM), contributes significant amounts of groundwater from deep circulation to streamflow. This fully 3D conceptual model is fundamentally different than watersheds characterized as 2D, those dominated by surface and shallow subsurface runoff, because 3D watersheds can have much longer flowpaths and mean residence times (up to 1000s of years). In contrast to Saguache Creek (volcanic bedrock) and Rio Hondo (crystalline metamorphic), the bedrock geology of the watersheds draining the Chuska Mountains is primarily comprised of sedimentary bedrock capped by extrusive volcanics. We test this conceptual model using a combination of stream gauging, tritium analyses, and endmember mixing analysis (EMMA) on the general ion chemistry and stable isotope composition of water samples collected in 2013-2016. Springs that emerge from the Chuska Sandstone are tritium dead indicative of a large component of pre-bomb pulse water in discharge and deeper 3D flow. EMMA indicates that most streamflow is generated from groundwater emerging from the Chuska Sandstone. Gaining/losing conditions in Whiskey Creek are strongly related to hydrostratigraphy as evidenced by a transition from gaining conditions largely found in the Chuska Sandstone to losing conditions where the underlying Chinle Formation outcrops. Although tritium in Whiskey Creek suggests 3D interactions are present, hydrostratigraphic and structural controls may

  7. Contrasting Nitrogen Fate in Watersheds using Agricultural and Water Quality Information

    NASA Astrophysics Data System (ADS)

    Essaid, H.; Baker, N. T.; McCarthy, K.

    2016-12-01

    A study combining Surplus Nitrogen (N) estimation with Principal Component (PCA) and End-Member-Mixing Analysis (EMMA) successfully reproduced, explained, and contrasted the general features of N fate and transport in diverse agricultural watersheds in Indiana (IN), Iowa (IA), Maryland (MD), Nebraska (NE), Mississippi (MS) and Washington (WA) that ranged in size from 5 to 1254 km2. Watershed Surplus N was determined by subtracting estimates of crop uptake and volatilization from estimates of N input from atmospheric deposition, plant fixation, fertilizer application and manure. Surplus N was ≤ 20% of total N input in the lower permeability watersheds of MS, IA and IN and most Surplus N in these watersheds was exported downstream. In contrast, Surplus N was > 20% of total N input in the more permeable watersheds of WA, NE and MD and only a fraction of the Surplus N was exported downstream. PCA and EMMA were used to identify end-members contributing to streamflow and NO3 load. Discharge of oxic groundwater (GW) to the stream was the primary source of stream NO3 load in the more permeable watersheds. In the less permeable watersheds GW was predominantly anoxic and tile drainage and runoff were the primary sources of stream NO3 load. These results suggest that a larger fraction of N applied at the land surface was not used by the plants and leached into the subsurface in more permeable watersheds. Although NO3-bearing oxic GW was the main source of stream NO3 in these watersheds, subsurface NO3 removal appeared to be occurring by denitrification along GW flow paths that encountered anoxic conditions and/or reactive streambed sediments. Although plants were able to more efficiently use N applied at the land surface in less permeable watersheds, what wasn't taken up by plants flowed directly to the stream with little opportunity for denitrification. Instream benthic processing was not apparent in small watersheds but became more important as watershed size increased.

  8. Afghanistan's gender apartheid.

    PubMed

    Carlisle, D

    This paper discusses the aftermath of gender apartheid in Afghanistan and its implications on the health care situation. Since 1996, when the radical Islamic Taliban movement took over two-thirds of Afghanistan, the country has faced severe restrictions. Women were told to stop working. Girls¿ schools were closed and access to health care was denied. To address this problem, Emma Bonino, the outspoken head of the European Community Humanitarian Office, has started an international campaign. Over the past 2 years the health care situation has somewhat improved. Women are now allowed to go to hospitals, provided that there are segregated male and female wards. In addition, female nurses are working in Afghan hospitals under certain conditions. The Taliban leaders have also allowed the health education program to continue.

  9. Correction of caudal deflections of the nasal septum with a modified Goldman septoplasty technique: how we do it.

    PubMed

    Lawson, William; Westreich, Richard

    2007-10-01

    Correcting deviations of the caudal septum can be challenging because of cartilage memory, the need to provide adequate nasal tip and dorsal septal support, and the longterm effects of healing. The authors describe a minimally invasive, endonasal approach to the correction of caudal septal deviations. The procedure involves a hemitransfixion incision, unilateral flap elevation, and cartilage repositioning by limited dissection and excision.

  10. Mississippi lieutenant governor visits Stennis

    NASA Image and Video Library

    2009-10-01

    Stennis Space Center Director Gene Goldman (left) stands with Mississippi Lt. Gov. Phil Bryant at the A-3 Test Stand construction site during an Oct. 1 visit by the state official. During his tour, Bryant was updated on construction of the first large test stand at Stennis since the 1960s. The A-3 stand will be used to conduct simulated high-altitude testing on the next generation of rocket engines that will take humans back to the moon and possibly beyond. In addition to touring Stennis facilities, Bryant visited the INFINITY Science Center construction site, where he was updated on work under way to construct a 72,000-square-foot facility that will showcase the science underpinning the missions of NASA and resident agencies at Stennis.

  11. A comparison of four measures of moral reasoning.

    PubMed

    Wilmoth, G H; McFarland, S G

    1977-08-01

    Kohlberg's Moral Judgment Scale, Gilligan et al.'s Sexual Moral Judgment Scale, Maitland and Goldman's Objective Moral Judgment Scale, and Hogan's Maturity of Moral Judgment Scale, were examined for reliability and inter-scale relationships. All measures except the Objective Moral Judgment Scale had good reliabilities. The obtained relations between the Moral Judgment Scale and the Sexual Moral Judgment Scale replicated previous research. The Objective Moral Judgment Scale was not found to validly assess the Kohlberg stages. The Maturity of Moral Judgment Scale scores were strongly related to the subjects's classification on the Kohlberg stages, and the scale appears to offer a reliable, quickly scored, and valid index of mature thought, although the scale's continuous scores do not permit clear stage classification.

  12. State of STEM (SoSTEM) Address

    NASA Image and Video Library

    2014-01-29

    Montgomery Blair High School Student Newspaper “Silver Chips” Online Editor-in-Chief Aanchal Johri, right, and Photo Editor Emma Howells, left, from Silver Spring, MD. interview Joey Hudy, Anthem, AZ, 16-year-old self-described “Maker” at the annual White House State of Science, Technology, Engineering, and Math (SoSTEM) address, Wednesday, Jan. 29, 2014, in the South Court Auditorium in the Eisenhower Executive Office Building on the White House complex in Washington. Joey sat with the First Lady at the President’s 2014 State of the Union Address after his first shot to fame in 2012 when he attended the White House Science Fair where the President took a turn using his “extreme marshmallow cannon” to launch a marshmallow across the East Room of the White House. Photo Credit: (NASA/Bill Ingalls)

  13. 17. Copy of a post card showing the Lavelle School ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Copy of a post card showing the Lavelle School and its first graduating class, c. 1890. The people are identified as: (1st row L to R) Charles Walker, Raymond Hornberger, Kenneth Keller, Dan Walker, Gilbert Lenker, and John Wetzel (from Locustdale); (2nd row L to R) Tim Snyder, Art Hornberger, John Wetzel (from Lavelle), ? Keller, Bright Enterline, Emerson Keller, Art Krah, and Leroy Henninger; (3rd row L to R) Hannah Wetzel, Vernie Hepler, Nona Snyder, Alice Dillman, Edith (Krah) Wolfgang, and Florence (Leach) Paul; (4th row L to R) Elva Paul, Vernie Wolfgang, Marie Enterline Walker, and Annie Hunter; (5th row L to R) Edna Walker, Martha Hornberger (Teacher), and Emma Dillman. (Copy of photo reproduced with permission from the Ashland Public ... - Lavelle School, Township Road 905, Main Street, Village of Lavelle, Lavelle, Schuylkill County, PA

  14. Emma Bovary, Hedda Gabler, and Harold Brodkey would not have lived without Charcot: hysteria in novels.

    PubMed

    Kaptein, A A

    2014-01-01

    Medical humanities is the interdisciplinary field of humanities (literature, philosophy, ethics, history, and religion), social science (anthropology, cultural studies, psychology, and sociology), and the arts (literature, theater, film, and visual arts), and their application to medical education and practice. In this chapter, the concept of 'hysteria' is put into a medical humanities perspective. We review the concept of hysteria concisely. Two novels and one autobiographical story are used as material in order to study how 'hysteria' is represented in literary work. Madame Bovary (Gustave Flaubert), Hedda Gabler (Henrik Ibsen), and A Story in an Almost Classical Mode (Harold Brodkey) were searched for elements that are characteristic of hysteria. Excessive emotion, dramatics, attention-seeking behavior, physical symptoms of unknown and unidentifiable organic causes, self-centered behavior, and flirtatious behavior are the six elements used to operationalize hysteria. It was found that these elements were present in both a quantitative and qualitative manner in the literary works examined. Acknowledging some limitations and suggesting some research areas and clinical implications, we conclude that literary works are useful in analyzing concepts in medicine. Also, more generally, using literary works seems to have a positive impact on readers, healthcare providers, and researchers in the healthcare domain. Studying novels and related literary work contributes to the body of knowledge of medical humanities.

  15. Connecting Fermion Masses and Mixings to BSM Physics - Quarks

    NASA Astrophysics Data System (ADS)

    Goldman, Terrence; Stephenson, Gerard J., Jr.

    2015-10-01

    The ``democratic'' mass matrix with BSM physics assumptions has been studied without success. We invert the process and use the ``democratic'' mass matrix plus a parametrization of all possible BSM corrections to analyze the implications of the observed masses and CKM weak interaction current mixing for the BSM parameter values for the up-quarks and down-quarks. We observe that the small mixing of the so-called ``third generation'' is directly related to the large mass gap from the two lighter generations. Conversely, the relatively large value of the Cabibbo angle arises because the mass matrices in the light sub-sector (block diagonalized from the full three channel problem) are neither diagonal nor degenerate and differ significantly between the up and down cases. Alt email:t.goldman@gmail.com

  16. Dementia and detectives: Alzheimer's disease in crime fiction.

    PubMed

    Orr, David Mr

    2018-01-01

    Fictional representations of dementia have burgeoned in recent years, and scholars have amply explored their double-edged capacity to promote tragic perspectives or normalising images of 'living well' with the condition. Yet to date, there has been only sparse consideration of the treatment afforded dementia within the genre of crime fiction. Focusing on two novels, Emma Healey's Elizabeth is Missing and Alice LaPlante's Turn of Mind, this article considers what it means in relation to the ethics of representation that these authors choose to cast as their amateur detective narrators women who have dementia. Analysing how their narrative portrayals frame the experience of living with dementia, it becomes apparent that features of the crime genre inflect the meanings conveyed. While aspects of the novels may reinforce problem-based discourses around dementia, in other respects they may spur meaningful reflection about it among the large readership of this genre.

  17. Estimation of tile drainage contribution to streamflow and nutrient loads at the watershed scale based on continuously monitored data.

    PubMed

    Arenas Amado, A; Schilling, K E; Jones, C S; Thomas, N; Weber, L J

    2017-09-01

    Nitrogen losses from artificially drained watersheds degrade water quality at local and regional scales. In this study, we used an end-member mixing analysis (EMMA) together with high temporal resolution water quality and streamflow data collected in the 122 km 2 Otter Creek watershed located in northeast Iowa. We estimated the contribution of three end-members (groundwater, tile drainage, and quick flow) to streamflow and nitrogen loads and tested several combinations of possible nitrate concentrations for the end-members. Results indicated that subsurface tile drainage is responsible for at least 50% of the watershed nitrogen load between April 15 and November 1, 2015. Tiles delivered up to 80% of the stream N load while providing only 15-43% of the streamflow, whereas quick flows only marginally contributed to N loading. Data collected offer guidance about areas of the watershed that should be targeted for nitrogen export mitigation strategies.

  18. ENVIRONMENTAL MONITORING, MODELING AND ASSESSMENT (EMMA): AN INTEGRATED DESIGN FOR EVALUATING RISK AND DISPARITIES IN RESIDENTIAL COMMUNITIES

    EPA Science Inventory

    This will be a student-led research project that incorporates chemical monitoring, integrated modeling, social surveys of residents and qualitative data collection from two sites in the Ventura River, California watershed. The design will define and identify potential pollutan...

  19. Metal pollution investigation of Goldman Park, Middletown Ohio: Evidence for steel and coal pollution in a high child use setting.

    PubMed

    Dietrich, Matthew; Huling, Justin; Krekeler, Mark P S

    2018-03-15

    A geochemical investigation of both ballfield sediment and street sediment in a park adjacent to a major steel manufacturing site in Middletown, Ohio revealed Pb, Cu, Cr and Zn exceeded background levels, but in heterogeneous ways and in varying levels of health concern. Pb, Sn, and Zn had geoaccumulation values>2 (moderate to heavy pollutants) in street sediment samples. Cr had a geoaccumulation value>1, while Ni, W, Fe and Mn had geoaccumulation values between 1 and 0 in street sediment. Street sediment contamination factors for respective elements are Zn (10.41), Sn (5.45), Pb (4.70), Sb (3.45), Cr (3.19), W (2.59), and Mn (2.43). The notable elements with the highest factors for ball fields are Zn (1.72), Pb (1.36), Cr (0.99), V (0.95), and Mn (1.00). High correlation coefficients of known constituents of steel, such as Fe and Mo, Ni and Cr, W and Co, W and V, as well as particulate steel and coal spherule fragments found by SEM suggest probable sourcing of some of the metals from the AK Steel facility directly adjacent to the park. However, overall extensive heterogeneity of metal pollutants in the area points to the difficulties in sourcing pollutant metals, with many outside sources likely contributing as well. This study demonstrates that different sediment media can be impacted by significantly different metal pollutants even when in very close proximity to a single source and points to unrecognized complexity in urban pollution processes in the region. This study pertains to large-scale regional importance, as Middletown, Ohio is indicative of a typical post-industrial Midwestern U.S. city where limited investigation has been conducted regarding urban pollution and sourcing of materials. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. A-3 Groundbreaking Ceremony

    NASA Image and Video Library

    2007-08-23

    NASA officials and government leaders participated in a groundbreaking event for a new rocket engine test stand at NASA's Stennis Space Center, Miss. Pictured (left to right) are Deputy Associate Administrator for Exploration Systems Doug Cooke, Pratt & Whitney Rocketdyne President Jim Maser, Stennis Space Center Director Richard Gilbrech, NASA Associate Administrator for Exploration Systems Scott Horowitz, NASA Deputy Administrator Shana Dale, Mississippi Gov. Haley Barbour, Sen. Thad Cochran, Sen. Trent Lott, Rep. Gene Taylor, SSC's Deputy Director Gene Goldman, and SSC's A-3 Project Manager Lonnie Dutreix. Stennis' A-3 Test Stand will provide altitude testing for NASA's developing J-2X engine. That engine will power the upper stages of NASA's Ares I and Ares V rockets. A-3 is the first large test stand to be built at SSC since the site's inception in the 1960s.

  1. INTERRELATIONSHIP BETWEEN TEMPERATURE AND SODIUM CHLORIDE ON GROWTH OF LACTIC ACID BACTERIA ISOLATED FROM MEAT-CURING BRINES.

    PubMed

    GOLDMAN, M; DEIBEL, R H; NIVEN, C F

    1963-05-01

    Goldman, Manuel (American Meat Institute Foundation, Chicago, Ill.), R. H. Deibel, and C. F. Niven, Jr. Interrelationship between temperature and sodium chloride on growth of lactic acid bacteria isolated from meat-curing brines. J. Bacteriol. 85:1017-1021. 1963.-An elevation of the temperature limit for growth of some Pediococcus homari (Gaffkya homari) and motile Lactobacillus strains could be effected by the addition of sodium chloride to the growth medium. At the optimal temperature for growth, sodium chloride was stimulatory, and as the temperature of incubation was increased a mandatory requirement for sodium chloride was manifested. At the optimal temperature for growth (30 C), the highest sodium chloride concentrations were tolerated; as the temperature was increased, this tolerance decreased, although the optimal sodium chloride concentration increased. No other substances were found that would replace the sodium chloride requirement at higher temperatures of incubation.

  2. Counterfactual reasoning for regretted situations involving controllable versus uncontrollable events: the modulating role of contingent self-esteem.

    PubMed

    Wilkinson, Meredith R; Ball, Linden J; Alford, David

    2015-01-01

    We report a study that examined the modulating impact of contingent self-esteem on regret intensity for regretted outcomes associated with controllable versus uncontrollable events. The Contingent Self-Esteem Scale (e.g., Kernis & Goldman, 2006) was used to assess the extent to which a person's sense of self-worth is based on self and others' expectations. We found that there was an influence of self-esteem contingency for controllable but not for uncontrollable regret types. For controllable regret types individuals with a high contingent (i.e., unstable) self-esteem reported greater regret intensity than those with a low contingent (i.e., stable) self-esteem. We interpret this finding as reflecting a functional and adaptive role of high contingent self-esteem in terms of mobilizing the application of counterfactual reasoning and planning mechanisms that can enable personal expectations to be achieved in the future.

  3. Europe’s Tired, Poor, Huddled Masses: Self-Selection and Economic Outcomes in the Age of Mass Migration†

    PubMed Central

    Abramitzky, Ran; Boustan, Leah Platt; Eriksson, Katherine

    2015-01-01

    During the age of mass migration (1850–1913), one of the largest migration episodes in history, the United States maintained a nearly open border, allowing the study of migrant decisions unhindered by entry restrictions. We estimate the return to migration while accounting for migrant selection by comparing Norway-to-US migrants with their brothers who stayed in Norway in the late nineteenth century. We also compare fathers of migrants and nonmigrants by wealth and occupation. We find that the return to migration was relatively low (70 percent) and that migrants from urban areas were negatively selected from the sending population. “Keep, ancient lands, your storied pomp!” cries she With silent lips. “Give me your tired, your poor, Your huddled masses yearning to breathe free, The wretched refuse of your teeming shore. Send these, the homeless, tempest-tost to me, I lift my lamp beside the golden door!”——Emma Lazarus (1883)1 PMID:26594052

  4. Changes in anthocyanidin levels during the maturation of color-fleshed potato (Solanum tuberosum L.) tubers.

    PubMed

    Šulc, Miloslav; Kotíková, Zora; Paznocht, Luboš; Pivec, Vladimír; Hamouz, Karel; Lachman, Jaromír

    2017-12-15

    Certain potato cultivars are capable of producing anthocyanin pigments in the potato skin and flesh and those pigments have been shown, together with other phytochemicals, to promote good health. Six common anthocyanidins (cyanidin, delphinidin, petunidin, pelargonidin, malvidin and peonidin) were analyzed weekly for 15weeks in red- and purple-fleshed potato cultivars (Red Emma, Königspurpur, Valfi and Blaue de la Mancha) grown in field conditions using a validated LC-(+ESI)MS/MS method. Pelargonidin was the major type detected in red-fleshed cultivars whereas petunidin was the major type detected in the purple ones. Neither cyanidin nor delphinidin were found in any of the cultivars. The anthocyanidin levels observed were as high as 78mg/100g FW during tuber growth; however, fully matured tubers contained only 10-39mg anthocyanidins/100gFW. Anthocyanidin levels were moderately correlated with global solar irradiation (r<0.6252) but not with rainfall or daily temperature. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Playing in or out of character: user role differences in the experience of interactive storytelling.

    PubMed

    Roth, Christian; Vermeulen, Ivar; Vorderer, Peter; Klimmt, Christoph; Pizzi, David; Lugrin, Jean-Luc; Cavazza, Marc

    2012-11-01

    Interactive storytelling (IS) is a promising new entertainment technology synthesizing preauthored narrative with dynamic user interaction. Existing IS prototypes employ different modes to involve users in a story, ranging from individual avatar control to comprehensive control over the virtual environment. The current experiment tested whether different player modes (exerting local vs. global influence) yield different user experiences (e.g., senses of immersion vs. control). A within-subject design involved 34 participants playing the cinematic IS drama "Emo Emma"( 1 ) both in the local (actor) and in global (ghost) mode. The latter mode allowed free movement in the virtual environment and hidden influence on characters, objects, and story development. As expected, control-related experiential qualities (effectance, autonomy, flow, and pride) were more intense for players in the global (ghost) mode. Immersion-related experiences did not differ over modes. Additionally, men preferred the sense of command facilitated by the ghost mode, whereas women preferred the sense of involvement facilitated by the actor mode.

  6. Femtosecond synchronism of x-rays and visible/infrared light in an x-ray free-electron laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adams, B. W.

    2007-12-15

    A way is proposed to obtain ultrashort pulses of intense infrared/visible light in few-femtosecond synchronism with x-rays from an x-ray free-electron laser (XFEL). It makes use of the recently proposed emittance-slicing technique [Emma et al., Phys. Rev. Lett. 92, 074801 (2004)] to both restrict the duration of self-amplified spontaneous emission (SASE) to a few femtoseconds and to lead to a coherence enhancement of near-infrared transition undulator radiation (CTUR). The x-rays and the near-infrared light originate within the XFEL undulator from the same slice of electrons within a bunch and are therefore perfectly synchronized with each other. An example of realizingmore » the scheme at the Linac Coherent Light Source is presented. A few side issues are explored briefly, such as the magnitude of the velocity term versus the acceleration term in the Lienard-Wiechert fields and the possible use of the CTUR as a diagnostic tool for the SASE process itself.« less

  7. Credibility assessments: operational issues and technology impact for law enforcement applications

    NASA Astrophysics Data System (ADS)

    Ryan, Andrew H., Jr.; Pavlidis, Ioannis; Rohrbaugh, J. W.; Marchak, Frank; Kozel, F. Andrew

    2003-09-01

    Law Enforcement personnel are faced with new challenges to rapidly assess the credibility of statements made by individuals in airports, border crossings, and a variety of environments not conducive to interviews. New technologies may offer assistance to law enforcement personnel in the interview and interrogation process. Additionally, homeland defense against terrorism challenges scientists to develop new methods of assessing truthfulness and credibility in humans. Current findings of four advanced research projects looking at emerging technologies in the credibility assessment are presented for discussion. This paper will discuss research efforts on four emerging technologies now underway at DoDPI and other institutions. These include: (1) Thermal Image Analysis (TIA); (2) Laser Doppler Vibrometry (LDV); (3) Eye Movement based Memory Assessment (EMMA); and (4) functional Magnetic Resonance Imaging (fMRI). A description each technique, the current state of these research efforts, and an overview of the potential for each of these emerging technologies will be provided.

  8. Spontaneous Emergence of Order in Vibrated Sand*

    NASA Astrophysics Data System (ADS)

    Swinney, Harry L.

    2004-05-01

    Granular media such as sand, pharmaceuticals, cereal, cosmetics, and asteroids are involved in many processes, yet granular media remain less well understood than fluids and solids. Vertically oscillating granular layers provide a test bed for theory and modeling of granular dynamics. Experiments on vertically oscillating granular layers have revealed a variety of spatial patterns that emerge spontaneously as a function of the container acceleration amplitude and frequency: stripes, squares, hexagons, spirals, and oscillons (localized structures). Molecular dynamics simulations yield results in quantitative accord with laboratory observations. Since the gradients of density and velocity are large over a particle mean free path, the applicability of continuum theory has been questionable. However, hydrodynamic equations proposed for dissipative particles yield results in surprising qualitative accord with the laboratory observations. *Work in collaboration with C. Bizon, D. Goldman, W.D. McCormick, S.J. Moon, E. Rericha, M. Shattuck, and J. Swift. Supported by DOE.

  9. Relationships between Speech Intelligibility and Word Articulation Scores in Children with Hearing Loss

    PubMed Central

    Ertmer, David J.

    2012-01-01

    Purpose This investigation sought to determine whether scores from a commonly used word-based articulation test are closely associated with speech intelligibility in children with hearing loss. If the scores are closely related, articulation testing results might be used to estimate intelligibility. If not, the importance of direct assessment of intelligibility would be reinforced. Methods Forty-four children with hearing losses produced words from the Goldman-Fristoe Test of Articulation-2 and sets of 10 short sentences. Correlation analyses were conducted between scores for seven word-based predictor variables and percent-intelligible scores derived from listener judgments of stimulus sentences. Results Six of seven predictor variables were significantly correlated with percent-intelligible scores. However, regression analysis revealed that no single predictor variable or multi- variable model accounted for more than 25% of the variability in intelligibility scores. Implications The findings confirm the importance of assessing connected speech intelligibility directly. PMID:20220022

  10. Elementary Particles and the Universe

    NASA Astrophysics Data System (ADS)

    Schwarz, John H.

    2005-07-01

    1. Excess baggage J. Hartle; 2. Through the clouds E. Witten; 3. Covariant foundations of the superparticle L. Brink; 4. Chiral symmetry and confinement T. Goldman; 5. The original fifth interaction Y. Neeman; 6. The mass hierarchy of leptons and quarks H. Fritzsch; 7. Spacetime duality in string theory J. H. Schwarz; 8. Symmetry and quasi-symmetry Y. Nambu; 9. On an exceptional non-associative superspace M. Gunaydin; 10. Algebra of reparametrization-invariant and normal ordered operators in open string field theory P. Ramond; 11. Superconductivity of an ideal charged boson system T. D. Lee; 12. Some remarks on the symmetry approach to nuclear rotational motion L. C. Biedebharn and P. Truini; 13. Uncomputability, intractability and the efficiency of heat engines S. Lloyd; 14. The new mathematical physics I. Singer; 15. For the birds V. Telegdi; 16. Gell-Mann's approach to physics A. Salam; 17. Remarks M. Goldberger.

  11. The causal theory of the resting potential of cells.

    PubMed

    Jäckle, Josef

    2007-12-07

    In this pedagogical article the causal theory of the resting potential of cells is presented, which for given extracellular ion concentrations predicts the intracellular ones simultaneously with the resting potential. In addition to the Na, K-pump, fixed charges on the membrane surfaces are taken into account. The equation determining the resting potential in the causal theory suggests a new explanation of the genesis of the resting potential. The usual criterion for an ion pump to be electrogenic is not relevant for the whole of the resting potential, and may therefore be misleading. The physical meaning of the Goldman-Hodgkin-Katz formula for the membrane potential as a diffusion potential is also explained and tested with numbers for the giant axon of the squid. A significant discrepancy between theory and experiment is found which calls for an experimental re-examination of the constitutive equations for passive potassium and sodium currents.

  12. Money and trust: relationships between patients, physicians, and health plans.

    PubMed

    Goold, S D

    1998-08-01

    In response to three articles on managed care by Allen Buchanan, David Mechanic, and Ezekiel Emanual and Lee Goldman (this issue), I discuss doctor-patient and organization-member trust and the moral obligations of those relationships. Trust in managed care organizations (providers of and payers for health care) stands in stark contrast to the current contractual model of health insurance purchase, but is more coherent with consumer expectations and with the provider role of such organizations. Such trust is likely to differ from that between doctors and patients. Financial reimbursement systems for physicians, one example of organizational change in our health system, can be evaluated for their impact on both kinds of trust according to their intrusiveness, openness, and goals. Although involving managed care enrollees in value-laden decisions that affect them is commendable, restrictions on or regulation of physician incentive systems may be better accomplished on a national level.

  13. Knowledge, Belief, and Science Education

    NASA Astrophysics Data System (ADS)

    Ferreira, Tiago Alfredo S.; El-Hani, Charbel N.; da Silva-Filho, Waldomiro José

    2016-10-01

    This article intends to show that the defense of "understanding" as one of the major goals of science education can be grounded on an anti-reductionist perspective on testimony as a source of knowledge. To do so, we critically revisit the discussion between Harvey Siegel and Alvin Goldman about the goals of science education, especially where it involves arguments based on the epistemology of testimony. Subsequently, we come back to a discussion between Charbel N. El-Hani and Eduardo Mortimer, on the one hand, and Michael Hoffmann, on the other, striving to strengthen the claim that rather than students' belief change, understanding should have epistemic priority as a goal of science education. Based on these two lines of discussion, we conclude that the reliance on testimony as a source of knowledge is necessary to the development of a more large and comprehensive scientific understanding by science students.

  14. The development of the Laryngeal Mask--a brief history of the invention, early clinical studies and experimental work from which the Laryngeal Mask evolved.

    PubMed

    Brain, A I

    1991-01-01

    The history of the invention and development of the Laryngeal Mask in the East End of London during the years 1981-88 is briefly described. The concept evolved from home-made prototypes built from the Goldman Dental Mask through a complex series of one-off latex models culminating in a primitive factory-made silicone cuff in 1986. This work defined the design parameters necessary to reconcile the needs for safety, reliability and ease of insertion while at the same time exploring the limits to possible use. In early 1988 the final version was tested by the inventor who had by this time used the device in more than 7500 patients undergoing routine surgery. From this experience a number of important lessons were learned relating to safe and effective use, which are summarized in the inventor's Instruction Manual. The importance of referring to this volume before use is stressed.

  15. Counterfactual Reasoning for Regretted Situations Involving Controllable Versus Uncontrollable Events: The Modulating Role of Contingent Self-Esteem

    PubMed Central

    Wilkinson, Meredith R.; Ball, Linden J.; Alford, David

    2015-01-01

    We report a study that examined the modulating impact of contingent self-esteem on regret intensity for regretted outcomes associated with controllable versus uncontrollable events. The Contingent Self-Esteem Scale (e.g., Kernis & Goldman, 2006) was used to assess the extent to which a person’s sense of self-worth is based on self and others’ expectations. We found that there was an influence of self-esteem contingency for controllable but not for uncontrollable regret types. For controllable regret types individuals with a high contingent (i.e., unstable) self-esteem reported greater regret intensity than those with a low contingent (i.e., stable) self-esteem. We interpret this finding as reflecting a functional and adaptive role of high contingent self-esteem in terms of mobilizing the application of counterfactual reasoning and planning mechanisms that can enable personal expectations to be achieved in the future. PMID:25883697

  16. INTERRELATIONSHIP BETWEEN TEMPERATURE AND SODIUM CHLORIDE ON GROWTH OF LACTIC ACID BACTERIA ISOLATED FROM MEAT-CURING BRINES1

    PubMed Central

    Goldman, Manuel; Deibel, R. H.; Niven, C. F.

    1963-01-01

    Goldman, Manuel (American Meat Institute Foundation, Chicago, Ill.), R. H. Deibel, and C. F. Niven, Jr. Interrelationship between temperature and sodium chloride on growth of lactic acid bacteria isolated from meat-curing brines. J. Bacteriol. 85:1017–1021. 1963.—An elevation of the temperature limit for growth of some Pediococcus homari (Gaffkya homari) and motile Lactobacillus strains could be effected by the addition of sodium chloride to the growth medium. At the optimal temperature for growth, sodium chloride was stimulatory, and as the temperature of incubation was increased a mandatory requirement for sodium chloride was manifested. At the optimal temperature for growth (30 C), the highest sodium chloride concentrations were tolerated; as the temperature was increased, this tolerance decreased, although the optimal sodium chloride concentration increased. No other substances were found that would replace the sodium chloride requirement at higher temperatures of incubation. PMID:14043988

  17. Simulation of a Driven Dense Granular Gas

    NASA Astrophysics Data System (ADS)

    Bizon, Chris; Shattuck, M. D.; Swift, J. B.; Swinney, Harry L.

    1998-11-01

    Event driven particle simulations quantitatively reproduce the experimental results on vibrated granular layers, including the formation of standing wave patterns(C. Bizon, M.D. Shattuck, J.B. Swift, W.D. McCormick, and H.L. Swinney, Phys. Rev. Lett. 80), pp. 57-60 (1998). and secondary instabilities(J.R. deBruyn, C. Bizon, M.D. Shattuck, D. Goldman, J.B. Swift, and H.L. Swinney, Phys. Rev. Lett. 81) (1998), to appear. . In these simulations the velocity distributions are nearly Gaussian when scaled with the local fluctuational kinetic energy (granular temperature); this suggests that inelastic dense gas kinetic theory is applicable. We perform simulations of a two-dimensional granular gas that is homogeneously driven with fluctuating forces. We find that the equation of state differs from that of an elastic dense gas and that this difference is due to a change in the distribution of relative velocities at collisions. Granular thermal conductivity and viscosity are measured by allowing the fluctuating forces to have large scale spatial gradients.

  18. Direct Effects on the Membrane Potential due to "Pumps" that Transfer No Net Charge

    PubMed Central

    Schwartz, Tobias L.

    1971-01-01

    The effects of active ionic transport are included in the derivation of a general expression for the zero current membrane potential. It is demonstrated that an active transport system that transfers no net charge (nonrheogenic) may, nevertheless, directly alter the membrane potential. This effect depends upon the exchange of matter within the membrane between the active and passive diffusion regimes. Furthermore, in the presence of such exchange, the transmembrane active fluxes measured by the usual techniques and the local pumped fluxes are not identical. Several common uses of the term “electrogenic pump” are thus shown to be inconsistent with each other. These inconsistencies persist when the derivation is extended to produce a Goldman equation modified to account for active transport; however, that equation is shown to be limited by less narrow constraints on membrane heterogeneity and internal electric field than those previously required. In particular, it is applicable to idealized mosaic membranes limited by these requirements. PMID:5113004

  19. Integration of auditory and visual communication information in the primate ventrolateral prefrontal cortex.

    PubMed

    Sugihara, Tadashi; Diltz, Mark D; Averbeck, Bruno B; Romanski, Lizabeth M

    2006-10-25

    The integration of auditory and visual stimuli is crucial for recognizing objects, communicating effectively, and navigating through our complex world. Although the frontal lobes are involved in memory, communication, and language, there has been no evidence that the integration of communication information occurs at the single-cell level in the frontal lobes. Here, we show that neurons in the macaque ventrolateral prefrontal cortex (VLPFC) integrate audiovisual communication stimuli. The multisensory interactions included both enhancement and suppression of a predominantly auditory or a predominantly visual response, although multisensory suppression was the more common mode of response. The multisensory neurons were distributed across the VLPFC and within previously identified unimodal auditory and visual regions (O'Scalaidhe et al., 1997; Romanski and Goldman-Rakic, 2002). Thus, our study demonstrates, for the first time, that single prefrontal neurons integrate communication information from the auditory and visual domains, suggesting that these neurons are an important node in the cortical network responsible for communication.

  20. Integration of Auditory and Visual Communication Information in the Primate Ventrolateral Prefrontal Cortex

    PubMed Central

    Sugihara, Tadashi; Diltz, Mark D.; Averbeck, Bruno B.; Romanski, Lizabeth M.

    2009-01-01

    The integration of auditory and visual stimuli is crucial for recognizing objects, communicating effectively, and navigating through our complex world. Although the frontal lobes are involved in memory, communication, and language, there has been no evidence that the integration of communication information occurs at the single-cell level in the frontal lobes. Here, we show that neurons in the macaque ventrolateral prefrontal cortex (VLPFC) integrate audiovisual communication stimuli. The multisensory interactions included both enhancement and suppression of a predominantly auditory or a predominantly visual response, although multisensory suppression was the more common mode of response. The multisensory neurons were distributed across the VLPFC and within previously identified unimodal auditory and visual regions (O’Scalaidhe et al., 1997; Romanski and Goldman-Rakic, 2002). Thus, our study demonstrates, for the first time, that single prefrontal neurons integrate communication information from the auditory and visual domains, suggesting that these neurons are an important node in the cortical network responsible for communication. PMID:17065454

  1. Toward the development of a rational scale in the use of human-figure drawings as a kindergarten screening measure.

    PubMed

    Goldman, R K; Velasco, M M

    1980-04-01

    The Draw-A-Person Test was individually administered to 120 kindergartners from diverse socioeconomic backgrounds, ranging in age from 4 yr. and 10 mo. to 6 yr. and 4 mo. This study was conducted to validate and expand Goldman and Warren's earlier work (1976) on the development of a rational scale for use as a kindergarten screening measure. Correlational analyses corroborate the earlier findings that body-part omissions are the most predictive items of emotional high risk. Factor analyses of the current data also replicate earlier findings in which two underlying cohesive factors emerged. The first factor has high loadings on peripheral body-part omissions; the second factor has high loadings on central body-part omission. The results suggest that an interchangeable number of body-part omissions together, rather than any one item, predict high emotional risk. Structural and content characteristics do not contribute significantly to the development of a kindergarten screening measure.

  2. Discretization of 3d gravity in different polarizations

    NASA Astrophysics Data System (ADS)

    Dupuis, Maïté; Freidel, Laurent; Girelli, Florian

    2017-10-01

    We study the discretization of three-dimensional gravity with Λ =0 following the loop quantum gravity framework. In the process, we realize that different choices of polarization are possible. This allows us to introduce a new discretization based on the triad as opposed to the connection as in the standard loop quantum gravity framework. We also identify the classical nontrivial symmetries of discrete gravity, namely the Drinfeld double, given in terms of momentum maps. Another choice of polarization is given by the Chern-Simons formulation of gravity. Our framework also provides a new discretization scheme of Chern-Simons, which keeps track of the link between the continuum variables and the discrete ones. We show how the Poisson bracket we recover between the Chern-Simons holonomies allows us to recover the Goldman bracket. There is also a transparent link between the discrete Chern-Simons formulation and the discretization of gravity based on the connection (loop gravity) or triad variables (dual loop gravity).

  3. Charge imbalance and Josephson effects in superconductor-normal metal mesoscopic structures

    NASA Astrophysics Data System (ADS)

    Volkov, A. F.

    2007-11-01

    We consider a SBS Josephson junction the superconducting electrodes S of which are in contact with normal metal reservoirs ( B means a barrier). For temperatures near Tc we calculate an effective critical current Ic* and the resistance of the system at the currents IGoldman collective modes. We find the position of Shapiro steps which deviates from that given by the Josephson relation.

  4. Electronic control of H+ current in a bioprotonic device with Gramicidin A and Alamethicin

    NASA Astrophysics Data System (ADS)

    Hemmatian, Zahra; Keene, Scott; Josberger, Erik; Miyake, Takeo; Arboleda, Carina; Soto-Rodríguez, Jessica; Baneyx, François; Rolandi, Marco

    2016-10-01

    In biological systems, intercellular communication is mediated by membrane proteins and ion channels that regulate traffic of ions and small molecules across cell membranes. A bioelectronic device with ion channels that control ionic flow across a supported lipid bilayer (SLB) should therefore be ideal for interfacing with biological systems. Here, we demonstrate a biotic-abiotic bioprotonic device with Pd contacts that regulates proton (H+) flow across an SLB incorporating the ion channels Gramicidin A (gA) and Alamethicin (ALM). We model the device characteristics using the Goldman-Hodgkin-Katz (GHK) solution to the Nernst-Planck equation for transport across the membrane. We derive the permeability for an SLB integrating gA and ALM and demonstrate pH control as a function of applied voltage and membrane permeability. This work opens the door to integrating more complex H+ channels at the Pd contact interface to produce responsive biotic-abiotic devices with increased functionality.

  5. The juggling paradigm: a novel social neuroscience approach to identify neuropsychophysiological markers of team mental models.

    PubMed

    Filho, Edson; Bertollo, Maurizio; Robazza, Claudio; Comani, Silvia

    2015-01-01

    Since the discovery of the mirror neuron system in the 1980s, little, if any, research has been devoted to the study of interactive motor tasks (Goldman, 2012). Scientists interested in the neuropsychophysiological markers of joint motor action have relied on observation paradigms and passive tasks rather than dynamic paradigms and interactive tasks (Konvalinka and Roepstorff, 2012). Within this research scenario, we introduce a novel research paradigm that uses cooperative juggling as a platform to capture peripheral (e.g., skin conductance, breathing and heart rates, electromyographic signals) and central neuropsychophysiological (e.g., functional connectivity within and between brains) markers underlying the notion of team mental models (TMM). We discuss the epistemological and theoretical grounds of a cooperative juggling paradigm, and propose testable hypotheses on neuropsychophysiological markers underlying TMM. Furthermore, we present key methodological concerns that may influence peripheral responses as well as single and hyperbrain network configurations during joint motor action. Preliminary findings of the paradigm are highlighted. We conclude by delineating avenues for future research.

  6. Speech production gains following constraint-induced movement therapy in children with hemiparesis.

    PubMed

    Allison, Kristen M; Reidy, Teressa Garcia; Boyle, Mary; Naber, Erin; Carney, Joan; Pidcock, Frank S

    2017-01-01

    The purpose of this study was to investigate changes in speech skills of children who have hemiparesis and speech impairment after participation in a constraint-induced movement therapy (CIMT) program. While case studies have reported collateral speech gains following CIMT, the effect of CIMT on speech production has not previously been directly investigated to the knowledge of these investigators. Eighteen children with hemiparesis and co-occurring speech impairment participated in a 21-day clinical CIMT program. The Goldman-Fristoe Test of Articulation-2 (GFTA-2) was used to assess children's articulation of speech sounds before and after the intervention. Changes in percent of consonants correct (PCC) on the GFTA-2 were used as a measure of change in speech production. Children made significant gains in PCC following CIMT. Gains were similar in children with left and right-sided hemiparesis, and across age groups. This study reports significant collateral gains in speech production following CIMT and suggests benefits of CIMT may also spread to speech motor domains.

  7. Freud's struggle with misogyny: homosexuality and guilt in the dream of Irma's injection.

    PubMed

    Lotto, D

    2001-01-01

    The highly condensed dream element trimethylamin is central to the dream of Irma's injection. After a brief review of the medical literature on timethylamine (TMA), it is suggested that two important meanings of this chemical and its properties lie in its disguised reference to disparaging views of women, as well as to Freud's homosexual connection to Wilhelm Fliess. Freud's misogynistic and homosexual impulses were stimulated by Fliess's recent surgical error committed while operating on Freud's patient Emma Eckstein. Evidence is presented that the collaboration between Freud and Fliess in performing an aggressive act toward a woman was for Freud an enactment of a childhood situation in which he and his nephew John had ganged up on John's sister Pauline. The later relationship between Freud, Jung, and Sabina Spielrein is seen as an additional reenactment of this childhood triangle. An examination of Freud's associations to and analysis of the Irma dream, as well as some of his later relationships with women, indicates that guilt and the wish to make reparation were also prominent themes in Freud's inner life.

  8. Newly Designed Apparatus for Measuring the Angular Dependent Surface Emittance in a Wide Wavelength Range and at Elevated Temperatures up to 1400°C

    NASA Astrophysics Data System (ADS)

    Rydzek, M.; Stark, T.; Arduini-Schuster, M.; Manara, J.

    2012-11-01

    An optimized apparatus for measuring the angular dependent surface emittance up to elevated temperatures has been designed. This emittance measurement apparatus (EMMA) is coupled to a Bruker Vertex 70v FTIR-spectrometer, so that a wavelength range from about 2 μm up to 25 μm is accessible. The central part of the new apparatus is a double walled, stainless steel vessel which can be evacuated or filled with various gases or with air. Inside the vessel a cylindrical tube furnace is pivot-mounted on a system of discs, for automatically rotating up to an angle of 180°. This allows both, the measurement at different detection angles (0° to 85°) and a consecutive measurement of sample and black-body reference without ventilating and opening the pot. The aim of this work is to present the newly designed emittance measurement apparatus which enables the determination of the angular dependent spectral emittance of opaque samples at temperatures up to 1400 °C. Next to the setup of the apparatus, the measurement results of various materials are presented at different detection angles.

  9. Can the relationship between doctors and drug companies ever be a healthy one?

    PubMed

    D'Arcy, Emma; Moynihan, Ray

    2009-07-21

    The financial ties between doctors and drug companies have come under intense scrutiny in recent years. Some commentators--such as Marcia Angell, former editor-in-chief of the New England Journal of Medicine--argue that the mission of doctors is fundamentally different to the mission of drug companies and that the ties between them should be completely cut. "Drug companies are investor owned businesses with a responsibility to maximise profits for their shareholders," says Angell. "That is quite different from the mission of the medical profession, which is to provide the best care possible for patients." Other commentators have argued that clinicians and drug companies do have some shared goals in aiming to maximize human health. In this debate, Emma D'Arcy, co-founder of a social networking site that facilitates interactions between doctors and drug companies, argues that it would be valuable to the public if we could establish "authentic alliances" between these professionals. But journalist Ray Moynihan argues that such alliances are prone to the corrupting influence of pharmaceutical industry money, and that disentanglement is a healthier alternative.

  10. Controls on the chemistry of runoff from an upland peat catchment

    NASA Astrophysics Data System (ADS)

    Worrall, Fred; Burt, Tim; Adamson, John

    2003-07-01

    This study uses 2 years of data from a detailed weekly water sampling programme in a 11·4 km2 upland peat catchment in the Northern Pennines, UK. The sampling comprised precipitation, soil-water samples and a number of streams, including the basin outlet. Samples were analysed for: pH, conductivity, alkalinity, Na, K, Ca, Mg, Fe, Al, Total N, SO4, Cl and colour. Principal component analysis (PCA) was used to identify end-members and compositional trends in order to identify controls on the development of water composition. The study showed that the direct use of PCA had several advantages over the use of end-member mixing analysis (EMMA) as it combines an analysis of mixing and evolving waters without the assumption of having to know the compositional sources of the water. In its application to an upland peat catchment, the study supports the view that shallow throughflow at the catotelm/acrotelm boundary is responsible for storm runoff generation and shows that baseflow is controlled by cation exchange in the catotelm and mixing with a base-rich groundwater.

  11. Lexical reorganization in Brazilian Portuguese: an articulatory study

    PubMed Central

    Meireles, A. R.; Barbosa, P. A.

    2008-01-01

    This work, which is couched in the theoretical framework of Articulatory Phonology, deals with the influence of speech rate on the change/variation from antepenultimate stress words into penultimate stress words in Brazilian Portuguese. Both acoustic and articulatory (EMMA) studies were conducted. On the acoustic side, results show different patterns of post-stressed vowel reduction according to the word type. Some words reduced their medial post-stressed vowels more than their final post-stressed vowels, and others reduced their final post-stressed vowels more than their medial post-stressed vowels. On the articulatory side, results show that the coarticulation degree of the post-stressed consonants increases with speech rate. Also, with the use of a measure called proportional consonantal interval (PCI), it was found in measurements of articulation that such measure is influenced by the word type. Three different groups of words were found according to their PCI. These results show how dynamical aspects influenced by speech rate increase are related to the lexical process of change/variation from antepenultimate stress words into penultimate ones. PMID:19885366

  12. Mysterious Roving Rocks of Racetrack Playa

    NASA Image and Video Library

    2017-12-08

    This group photo of the LPSA interns and trip leaders was taken at Tea Kettle Junction in Death Valley, Calif. (Standing on left side, left to right): Kristopher Schwebler, Valerie Fox, Emily Kopp, Kyle Yawn, Dan Burger, Ian Schoch, Devon Miller; (left to right, sitting) Justin Wilde, Jessica Marbourg, Maggie McAdam (a trip leader), Leva McIntire, Ann Parsons (a trip leader), Mindy Krzykowski, Emma McKinney, Cynthia Cheung (LPSA principal investigator and a trip leader), George Fercana; (standing on right side): Kynan Rilee, Gregory Romine, Clint Naquin, Gunther Kletetschka (a trip leader), Andrew Ryan, and in the very back, Brian Jackson (a trip leader). Photo credit: NASA/GSFC/ Leva McIntire/LPSA intern To read a feature story on the Racetrack Playa go to: www.nasa.gov/topics/earth/features/roving-rocks.html NASA Goddard Space Flight Center is home to the nation's largest organization of combined scientists, engineers and technologists that build spacecraft, instruments and new technology to study the Earth, the sun, our solar system, and the universe. Follow us on Twitter Join us on Facebook

  13. Dataset on daytime outdoor thermal comfort for Belo Horizonte, Brazil.

    PubMed

    Hirashima, Simone Queiroz da Silveira; Assis, Eleonora Sad de; Nikolopoulou, Marialena

    2016-12-01

    This dataset describe microclimatic parameters of two urban open public spaces in the city of Belo Horizonte, Brazil; physiological equivalent temperature (PET) index values and the related subjective responses of interviewees regarding thermal sensation perception and preference and thermal comfort evaluation. Individuals and behavioral characteristics of respondents were also presented. Data were collected at daytime, in summer and winter, 2013. Statistical treatment of this data was firstly presented in a PhD Thesis ("Percepção sonora e térmica e avaliação de conforto em espaços urbanos abertos do município de Belo Horizonte - MG, Brasil" (Hirashima, 2014) [1]), providing relevant information on thermal conditions in these locations and on thermal comfort assessment. Up to now, this data was also explored in the article "Daytime Thermal Comfort in Urban Spaces: A Field Study in Brazil" (Hirashima et al., in press) [2]. These references are recommended for further interpretation and discussion.

  14. A historical appraisal of America's experience with "pyromania"--a diagnosis in search of a disorder.

    PubMed

    Geller, J L; Erlen, J; Pinkus, R L

    1986-01-01

    like the preceding period, the conception of pyromania as a specific disorder wanes but never dies, as advocacy for the psychodynamic (replacing moral) approach diminishes but does not disappear. The cyclical nature of pyromania has parallels in cycles of reform in standards of civil commitment (Livermore, Malmquist & Meehl, 1958; Dershowitz, 1974), in the use of physical therapies and medications (Tourney, 1967; Mora, 1974), in treatment of the chronically mentally ill (Deutsch, 1949; Morrissey & Goldman, 1984), and in institutional practices (Treffert, 1967; Morrissey, Goldman & Klerman (1980).(ABSTRACT TRUNCATED AT 400 WORDS)

  15. A stepwise approach to stroke surveillance in Brazil: the EMMA (Estudo de Mortalidade e Morbidade do Acidente Vascular Cerebral) study.

    PubMed

    Goulart, Alessandra C; Bustos, Iara R; Abe, Ivana M; Pereira, Alexandre C; Fedeli, Ligia M; Benseñor, Isabela M; Lotufo, Paulo A

    2010-08-01

    Stroke mortality rates in Brazil are the highest in the Americas. Deaths from cerebrovascular disease surpass coronary heart disease. To verify stroke mortality rates and morbidity in an area of São Paulo, Brazil, using the World Health Organization Stepwise Approach to Stroke Surveillance. We used the World Health Organization Stepwise Approach to Stroke Surveillance structure of stroke surveillance. The hospital-based data comprised fatal and nonfatal stroke (Step 1). We gathered stroke-related mortality data in the community using World Health Organization questionnaires (Step 2). The questionnaire determining stroke prevalence was activated door to door in a family-health-programme neighbourhood (Step 3). A total of 682 patients 18 years and above, including 472 incident cases, presented with cerebrovascular disease and were enrolled in Step 1 during April-May 2009. Cerebral infarction (84.3%) and first-ever stroke (85.2%) were the most frequent. In Step 2, 256 deaths from stroke were identified during 2006-2007. Forty-four per cent of deaths were classified as unspecified stroke, 1/3 as ischaemic stroke, and 1/4 due to haemorrhagic subtype. In Step 3, 577 subjects over 35 years old were evaluated at home, and 244 cases of stroke survival were diagnosed via a questionnaire, validated by a board-certified neurologist. The population demographic characteristics were similar in the three steps, except in terms of age and gender. By including data from all settings, World Health Organization stroke surveillance can provide data to help plan future resources that meet the needs of the public-health system.

  16. Effect of worker contacts on risk of child maltreatment recurrence among CPS-involved children and families.

    PubMed

    Halverson, Julie L; Russell, Jesse Rio; Kerwin, Colleen

    2018-06-05

    The mission and responsibility of child protective services (CPS) is to investigate maltreatment; intervene to protect children from harm; and promote safety, permanency, and well-being (DePanfilis & Salus, 2003; Goldman, Salus, Wolcott, & Kennedy, 2003). In 2015, approximately 7.2 million children in the United States were referred to CPS agencies, and 3.4 million children had an investigation or received an alternative response (US Department of Health & Human Services, 2017). Fluke, Shusterman, Hollinshead, and Yuan (2005) found that about one third of children with an allegation of maltreatment would have at least one re-report within a five-year period. Research indicates that the rates of child maltreatment or changes in indicators of child maltreatment have remained unchanged over time (Gilbert et al., 2012). Despite policies aimed at reducing or preventing maltreatment, the development of CPS systems across the United States, and a CPS workforce, the aggregate effects of the CPS system, services, and worker efforts are not well understood. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Multi-scale simulations of space problems with iPIC3D

    NASA Astrophysics Data System (ADS)

    Lapenta, Giovanni; Bettarini, Lapo; Markidis, Stefano

    The implicit Particle-in-Cell method for the computer simulation of space plasma, and its im-plementation in a three-dimensional parallel code, called iPIC3D, are presented. The implicit integration in time of the Vlasov-Maxwell system removes the numerical stability constraints and enables kinetic plasma simulations at magnetohydrodynamics scales. Simulations of mag-netic reconnection in plasma are presented to show the effectiveness of the algorithm. In particular we will show a number of simulations done for large scale 3D systems using the physical mass ratio for Hydrogen. Most notably one simulation treats kinetically a box of tens of Earth radii in each direction and was conducted using about 16000 processors of the Pleiades NASA computer. The work is conducted in collaboration with the MMS-IDS theory team from University of Colorado (M. Goldman, D. Newman and L. Andersson). Reference: Stefano Markidis, Giovanni Lapenta, Rizwan-uddin Multi-scale simulations of plasma with iPIC3D Mathematics and Computers in Simulation, Available online 17 October 2009, http://dx.doi.org/10.1016/j.matcom.2009.08.038

  18. [Trabeculotomy ab interno combined with extracapsular cataract extraction and IOL implantation].

    PubMed

    Alekseev, B N; Ermolaev, A P

    2003-01-01

    We made a total of 96 surgeries of extracapsular cataract extraction and IOL implantation combined with trabeculotomy ab interno during a period of 7 years. Patients with both open-angle and narrow-angle glaucoma of stages I and II and with the intraocular pressure (IOP) below or equal to 23 mm Hg according to Goldman under the conditions of hypotensive medicamental regimen were selected for surgery. After IOL was implanted into the lens bag, trabeculotomy ab interno was implemented as stage 2. A special mirror, introduced through the cataract incision, was used for direct gonioscopic monitoring. The trabecula was incised by the edge of a curved surgical knife under direct visual control. We regarded bleeding from the opened sinus as a favorable sign indicative of that the intrascleral collectors were intact. Only minor hyphemas were registered as postoperative complications; there was not a single case of ciliary-and-choroidal detachment. IOP was compensated for, in 6 months after surgery, in 94% of patients--69.8% of them did not use any hypotensive drops.

  19. Is imatinib still the best choice as first-line oral TKI.

    PubMed

    Bansal, Shweta

    2014-01-01

    Targeted therapy is the buzz word these days. A decade back the emergence of tyrosine kinase inhibitor Imatinib on the horizon, as the targeted therapy, had captured the imagination of everyone in the field of cancer. It is encouraging to see a large number of patients getting relief from deadly CML disease and leading a good quality of life with the help of this drug. However, sky is not the limit and now we have second and third generation tyrosine kinase inhibitors. I still remember the sagacious smile on the face of late Dr. John Goldman, when I asked him about his preferred choice and he replied and I quote "this is going to be the debate of the decade." Here I take the opportunity to contribute to this debate. I have scrutinized various aspects of the three TKIs, now recommended, for the treatment of CML. I'm still convinced it is too early to shift our practice completely towards 2G TKI as more time is required to make a clear recommendation.

  20. Predictors of long-term survival among first-ever ischemic and hemorrhagic stroke in a Brazilian stroke cohort.

    PubMed

    Goulart, Alessandra C; Fernandes, Tiotrefis G; Santos, Itamar S; Alencar, Airlane P; Bensenor, Isabela M; Lotufo, Paulo A

    2013-05-24

    Few studies have examined both ischemic and hemorrhagic stroke to identify prognostic factors associated to long-term stroke survival. We investigated long-term survival and predictors that could adversely influence ischemic and hemorrhagic first-ever stroke prognosis. We prospectively ascertained 665 consecutive first-ever ischemic and hemorrhagic stroke cases from "The Study of Stroke Mortality and Morbidity" (The EMMA Study) in a community hospital in São Paulo, Brazil. We evaluated cardiovascular risk factors and sociodemographic characteristics (age, gender, race and educational level). We found a lower survival rate among hemorrhagic cases compared to ischemic stroke cases at the end of 4 years of follow-up (52% vs. 44%, p = 0.04). The risk of death was two times higher among people with ischemic stroke without formal education. Also, we found consistently higher risk of death for diabetics with ischemic stroke (HR = 1.45; 95% CI = 1.07-1.97) compared to no diabetics. As expected, age equally influenced on the high risk of poor survival, regardless of stroke subtype. For ischemic stroke, the lack of formal education and diabetes were significant independent predictors of poor long-term survival.