The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).
DOEpatents
... DEFENCE r, w JDEFENSE Liquid Chromatography Electrospray Ionization ... Page 2. Liquid Chromatography Electrospray Ionization ...
DTIC Science & Technology
, J. J. Zacca, A. O. Maldaner and M. N. Eberlin, Analyst, 2010, 135, 745�750. 23 D. R. Ifa, L. M. Gumaelius, L. S. Eberlin, N. E. Manicke and R. G. Cooks, Analyst, 2007, 132, 461�467. 24 S. Zervos and A
E-print Network
Atmospheric pressure imaging mass spectrometry is a rapidly expanding field that offers advantages in the ability to study biological systems in their native condition, simplified sample preparation, and high-throughput experiments. In laser ablation electrospray ionization (LAESI), the native water molecules in biological tissues ...
PubMed
Atmospheric pressure imaging mass spectrometry is a rapidly expanding field that offers advantages in the ability to study biological systems in their native condition, simplified sample preparation, and high-throughput experiments. In laser ablation electrospray ionization (LAE-SI), the native water molecules in biological tissues ...
PubMed Central
Analysis of biochemicals in single cells is important for understanding cell metabolism, cell cycle, adaptation, disease states, etc. Even the same cell types exhibit heterogeneous biochemical makeup depending on their physiological conditions and interactions with the environment. Conventional methods of mass spectrometry (MS) used for the analysis of biomolecules in single cells rely on ...
Electrospray ionization emitter arrays, as well as methods for forming electrosprays, are described. The arrays are characterized by a radial configuration of three or more nano-electrospray ionization emitters without an extractor electrode. The methods are characterized by distributing fluid ...
and reserpine, respectively, and quantitation capabilities with a four-decade dynamic range. We demonstrated containing both verapamil and reserpine at concentrations ranging from 1 nM to 10 mM were prepared with 50]+ and [reserpine + H]+ and their concentrations. The linear regression in Figure 2 yielded a correlation
Laser ablation of single cells through a sharpened optical fiber is used for the detection of metabolites by laser ablation electrospray ionization (LAESI) mass spectrometry (MS). Ablation of the same Allium cepa epidermal cell by consecutive pulses indicates the rupture of the cell wall by the ...
NASA Astrophysics Data System (ADS)
This letter describes the coupling of ambient pressure transmission geometry laser ablation with a liquid phase sample collection method for surface sampling and ionization with subsequent mass spectral analysis. A commercially available autosampler was adapted to produce a liquid droplet at the end of the syringe injection needle while in close proximity ...
... Accession Number : ADA102234. Title : Laser Ablation and Resonance Ionization Spectroscopy (LARIS) for Trace Analysis of Solids. ...
... FOREIGN TECHNOLOGY DIVISION CARBON/CARBON COMPOSITION ABLATION EFFECTS ON IONIZED BOUNDARY LAYERS by ...
Jan 22, 2011 ... Title: The effect of salts on electrospray ionization of amino acids in the negative mode. Authors: Kim, H. I.. Johnson, P. V. ...
NASA Website
... An external source electrospray ionization (ESI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometer has been used to study the ...
... Abstract : An external source electrospray ionization (ESI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometer has been used to ...
