BACKGROUND: Antibody-mediated rejection (ABMR) following kidney transplantation is associated with poor allograft survival. Conventional treatment based on plasmapheresis (PPH) and the administration of intravenous immunoglobulins (IVIG) is not satisfactory. Two compounds, more specifically targeting B cells and plasma cells, may help to improve the prognosis: rituximab, a ...
PubMed
Various experimental methods, used in Chair of Quantum Engineering and Metrology for determination of the hyperfine structure of electronic levels in lanthanides atoms and ions, are presented. In turn the spectroscopic methods on an atomic beam (laser induced fluorescence and laser-rf double resonance ABMR-LIRF), laser-rf double ...
NASA Astrophysics Data System (ADS)
The hfs of 103Ag (T1/2 = 66 min) has been investigated with the atomic-beam magnetic-resonance (ABMR) method. ?? and ?I have been determined independently, and the results are ?? = 39 700 (500) MHz and ?I = + 4.45 (5) n.m. The hfs anomaly ?107103 has been determined to be + 3.4 (1.7)%. Theoretical calculations give ?107103 = 3.9%. For I = 5, there is a ...
Aspects of nuclear structure studies are discussed in which atomic spectroscopy plays an important part. The experimental techniques span radiofrequency spectroscopy, in particular atomic beam magnetic resonance (ABMR), dispersive or interference spectros...
National Technical Information Service (NTIS)
The diagnosis and treatment of anti-donor antibody-mediated rejection or humoral rejection (ABMR) is one of the main discussions at the moment in kidney transplantation. The search for histopathological markers that help us to diagnose ABMR has been more problematic, in contrast to the histological expression of cellular or tubulointerstitial rejection. ...
The presence of preformed, donor-specific alloantibodies inpatients undergoing renal transplantation is associated with a high risk of hyperacute and acute antibody-mediated rejection (ABMR), and often limits potential recipients' access to organs from living and deceased donors. Over the last decade, understanding of ABMR has improved markedly and given ...
Marked peritubular capillary basement membrane (PTCBM) multilayering, the ultrastructural feature of chronic antibody-mediated rejection (ABMR) of kidney allografts, was found to correspond histologically to PTCs with thickened BMs; such PTCs have been suggested as a novel histological marker of chronic rejection. We investigated whether scoring of PTCBM thickening can ...
In order to reach short-lived nuclides far from stability for hyperfine structure investigations, the atomic-beam apparatus formerly at Uppsala has been reconstructed and connected on-line with the ISOLDE isotope separator at CERN. The design and performa...
Hyperfine structure measurements have been performed in some neutron-deficient gold isotopes, using on-line atomic-beam magnetic resonance (ABMR) techniques at the ISOLDE facility, CERN. The following results have been obtained: 185Au, I = 5/2; 187Au, ?v = 44.35(60) GHz, ? = 0.72(7) n.m. and 188Au, ?v = +/- 2992(30) MHz. A discussion of the influence of the hyperfine anomaly ...
