... INTELLIGENT DETECTION OF ABNORMAL NEONATAL CEREBRAL HAEMODYNAMICS IN A NEONATAL INTENSIVE CARE ENVIRONMENT ...

Global cerebral blood flow, oxidative brain metabolism, and the cerebral arteriovenous differences of amino acids and ammonia were studied in 20 clinically diagnosed patients with early-onset dementia of Alzheimer type (DAT). Eleven healthy age-matched subjects and 15 healthy young volunteers served as controls. The most prominent ...

Cerebral PET with [18F]-2-fluoro-2-deoxy-D-glucose has been performed in four patients with neurofibromatosis type 1 (NF1) to assess the relation between cerebral metabolic activity, MRI, and the presence of neurological symptoms, including seizures, as well as mental and language retardation. Widespread hypometabolism occurred in ...

Abnormalities in the oxidative metabolism of glucose in human cerebral gliomas have been studied in seven patients using positron emission tomography. Measurements of regional cerebral blood flow and oxygen consumption were obtained using the oxygen-15 steady-state inhalation technique. Values of regional ...

Global cerebral blood flow and the cerebral metabolic rates of oxygen, CO2, glucose and lactate were studied in 11 patients aged 61-78 years who had been clinically diagnosed as suffering from incipient late-onset dementia of the Alzheimer type (DAT), and in 7 patients aged 66-83 years, in whom advanced late-onset DAT had been ...

... Accession Number : ADA082268. Title : Role of Glucose-6-Phosphate in Cerebral Dysfunction Following Hypoxia and Hypotension,. ...

... Accession Number : AD0737819. Title : Investigation of Human Cerebral and Peripheral Glucose and Free Amino Acid Metabolism. ...

Study DesignA prospective study.PurposeTo assess postoperative changes in cerebral glucose metabolism in anxiety patients with lumbar spinal stenosis (SS).Overview of LiteratureAlthough an association between preoperative anxiety and abnormal cerebral glucose metabolism may exist, only a ...

This study was undertaken to investigate regional metabolic abnormalities and to determine the effects of modafinil in narcoleptics on cerebral glucose metabolism using [(18)F] fluorodeoxyglucose positron emission tomography (FDG PET). Eight narcoleptic patients participated in the study. Two [(18)F] FDG PET scans were obtained before ...

This commentary considers some of the factors that affect cerebral glucose metabolism in patients with traumatic brain injury. A study recently reported in Critical Care suggested a blood glucose range that may optimize cerebral glucose utilization; the findings of this study are evaluated and ...

Although metabolic abnormalities have been linked with poor outcome after subarachnoid hemorrhage, there are limited data addressing the impact of glycemic control or benefits of glucose management after aneurysmal subarachnoid hemorrhage. A systematic literature search was conducted of English-language articles describing original research on glycemic ...

The aim was to study brain involvement in myotonic dystrophy type 1 by single photon emission tomography (SPECT) and positron emission tomography (PET). 58 DM1 patients were subjected to SPECT; 17 to both SPECT and PET. SPECT patients were grouped as 'normally perfused' and 'abnormally perfused'; PET patients as 'normal performers' and 'abnormal ...

Studies of cerebral oxygen and cerebral glucose consumption during hyperthermia indicated that at a body temperature of 42C, cerebral oxygen consumption increased and glucose consumption was unchanged compared to control temperature. From these data and e...

Circulating endothelial cells (CECs) are nonhematopoetic mononuclear cells in peripheral blood that are dislodged from injured vessels during cardiovascular disease, systemic vascular disease, and inflammation. Their occurrence during cerebrovascular insults has not been previously described. Epileptic seizures cause the long-term loss of cerebrovascular endothelial dilator function. We ...

Circulating endothelial cells (CECs) are nonhematopoetic mononuclear cells in peripheral blood that are dislodged from injured vessels during cardiovascular disease, systemic vascular disease, and inflammation. Their occurrence during cerebrovascular insults has not been previously described. Epileptic seizures cause the long-term loss of cerebrovascular endothelial dilator function. We ...

... brain in the cerebral hemispheres, cerebellum, brainstem, or hippocampus. The structural abnormalities found in NMDs include schizencephaly, ...

We analyzed the interictal [18F]fluoro-2-deoxy-D-glucose positron emission tomography (FGD-PET) and single photon emission computed tomography with technetium-99m-hexamethyl-propyleneamine oxime (HMPAO-SPECT) in two epileptic patients with periventricular nodular heterotopia (PNH). In both cases, we found both the glucose metabolism and the perfusion of ...

Purpose:To determine cerebral glutamate turnover rate in partial�ornithine transcarbamylase deficiency (OTCD) patients by using carbon 13 (¹³C) magnetic resonance (MR) spectroscopy.Materials and Methods:The study was performed with approval of the institutional review board, in compliance with HIPAA regulations, and with written informed consent of the ...

The method of Reinmuth et al for determining cerebral blood flow (CBF) (Arch. Neurol., 12:49-66, 1965) has been adapted for use on dogs. Measurements of CBF, cerebral vascular resistance (CVR) and cerebral oxygen and glucose consumptions were made at rect...

Interest in the control feeding and has increased as a result of the obesity epidemic and rising incidence of metabolic diseases. The brain detects alterations in energy stores and triggers metabolic and behavioral responses designed to maintain energy balance. Energy homeostasis is controlled mainly by neuronal circuits in the hypothalamus and brainstem, whereas reward and motivation aspects of ...

in children with cerebral palsy is challenging. Musculoskeletal surgeries and other treatments, such as toneComputer modeling of gait abnormalities in cerebral palsy: application to treatment planning A. S, Stanford, CA, USA The treatment of gait abnormalities in persons with cerebral palsy is ...

Abnormal cerebral energy metabolism due to dysfunction of mitochondrial electron transport has been implicated in the pathogenesis of Parkinson Disease (PD). However, in vivo data of mitochondrial dysfunction has been inconsistent. We directly investigated mitochondrial oxidative metabolism in vivo in 12 patients with early, never-medicated PD and 12 ...

BackgroundThe long-term neurological consequences of HIV infection and treatment are not yet completely understood. In this study we examined the prevalence of cerebral metabolic abnormalities among a cohort of neurologically intact HIV patients with fully suppressed HIV viral loads. Concomitant analyses of circulating brain derived neurotrophic factor ...

We used single photon emission computed tomography (SPECT) to study 15 patients with Alzheimer's disease and nine controls. Iofetamine hydrochloride I 123 uptake data were recorded from the entire brain using a rotating gamma camera. Activity ratios were measured for the frontal, posterior parietal, posterior, medial, and lateral cortical temporal regions and striate cortex and were ...

Nesidioblastosis is a rare disorder in pediatric surgery. It is caused by hypertrophy and hyperplasia of the islands of Langerhans, and can lead to persistent hyperinsulinemic hypoglycemia. If appropriate treatment is delayed there is a high risk of the development of cerebral palsy, impaired mental development, epilepsy or other forms of irreversible brain damage, so early ...

ObjectiveWe sought to determine the impact of insulin resistance short of diabetes on the arteriolar-to-venular ratio (AVR). In addition, we ascertained whether AVR was related to cerebral atrophy.DesignCross-sectional designParticipantsForty-six non-diabetic subjects with normal glucose tolerance and varying degrees of insulin resistance, 43 to 77 years ...

Atherosclerosis; Osteoporosis; Obesity; Glucose Abnormalities; Alzheimer's Disease; Vascular Dimentia

HIV Infections; Lipid Metabolism; Glucose Metabolism; Metabolic Abnormality; Lipodystrophy; Cardiovascular Disease

OBJECTIVERecent data demonstrated that glucose sensing in different tissues is initiated by an intracellular redox signaling pathway in physiological conditions. However, the relevance of such a mechanism in metabolic disease is not known. The aim of the present study was to determine whether brain glucose hypersensitivity present in obese Z�cker rats is ...

In this paper, we investigate an advanced monitoring system for a neonatal intensive care unit The system intelligently detects abnormal neonatal cerebral Doppler ultrasound signals by means of principal component analysis and a non-normalised compensator...

BACKGROUND: Chronic orthostatic intolerance (OI) is characterized by symptoms of inadequate cerebral