The mechanisms underlying the abnormal glucose tolerance in patients who had undergone vagotomy and pyloroplasty were investigated by measuring the rates of absorption of ingested glucose and the clearance rate of glucose using tracer methods. These methods are based on labeling a 100-g oral ...

Hepatitis C and type 2 diabetes mellitus (DM) are two rising epidemics with significant impact on each other. Hepatitis C-infected patients have a higher incidence of type 2 diabetes, and diabetic patients have a high prevalence of hepatitis C. There is mounting evidence that glucose abnormalities have a negative impact on the disease progression as well ...

The lactose tolerance test was abnormal in 97% of 140 healthy adult Thais, while glucose and sucrose tolerance tests were normal in nearly all. A selective deficiency of intestinal lactase activity was found that accounts for these results. Feeding 50 g o...

OBJECTIVE�Hemipancreatectomy (HPx) for the purpose of organ donation has been associated with a 25% risk of developing abnormal glucose tolerance or diabetes in the year after surgery. Since 1997, the University of Minnesota has imposed criteria to prevent potential donors with clinical features associated with an increased diabetes ...

A population survey in 1982 has confirmed that Nauruan adults suffer from an extremely high prevalence of Type 2 (noninsulin-dependent) diabetes mellitus. The crude population prevalence of Type 2 diabetes was 24%. Abnormal glucose tolerance (impaired glucose tolerance and diabetes) was present ...

Among the laboratory methods and test procedures used for the diagnosis of diabetes mellitus in clinical practice, the oral glucose tolerance test, if performed properly, remains the cornerstone in the definitive diagnosis of diabetes. The intravenous glucose tolerance or the tolbutamide response tests may be ...

Of 3,563 consecutive obstetric patients undergoing glucose screening, 517 (14.5%) were found to have plasma values of greater than or equal to 140 mg%, and 74 (14.3%) of 517 were found to be diabetic on standard oral glucose tolerance testing, for an overall incidence of 2.1%. There was no absolute value on the ...

ObjectiveThe association of nonalcoholic fatty liver disease (NAFLD) with insulin resistance and metabolic syndrome has been documented for obese men and middle-aged men. This study was designed to determine the relationship between NAFLD and the oral glucose tolerance test (OGTT) to predict preclinical diabetes in nondiabetic young male patients (<30 ...

The progress of a young woman presenting with diabetic ketoacidosis is described. She was managed as for a new presentation of type 1 diabetes, but was subsequently diagnosed with acromegaly due to a large pituitary tumour. Following treatment for this, and relative normalisation of growth hormone levels, she was able to stop insulin completely. Subsequently, an oral glucose ...

In a group of young patients with thalassaemia and iron overload treated by subcutaneous infusions of desferrioxamine we have found a number of minor alterations in retinal function. The incidence of such changes is not related to drug dosage or to ferritin level but to abnormality of the extended glucose tolerance test.

Diabetes mellitus was diagnosed by clinical demonstration of hyperglycemia, glycosuria, and abnormal glucose tolerance tests in 2 rhesus monkeys involved in a latent radiation effects study. Radiation induction of the disease is questionable because of lo...

A longitudinal study of 266 randomly selected non-diabetic Nauruans (215 normal subjects, 51 with impaired glucose tolerance) has permitted the natural history of impaired glucose tolerance to be studied in this Micronesian population. Nauruans are known to suffer from a very high prevalence of ...

... to altitude and administered amphetamine was significantly ... TOXIC TOLERANCES, *HIGH ALTITUDE), AMPHETAMINES, GLUCOSE, BLOOD ...

Impaired glucose tolerance (IGT) and Type 2 diabetes mellitus (DM) are common in women with polycystic ovary syndrome (PCOS) in American studies. However, whether rates are similar in other countries with a lower frequency of insulin resistance is not clear. Our purpose was to investigate the prevalence of abnormal ...

AIMS: Evaluate the reproducibility and relationship of various metabolic tests conducted as part of the Diabetes Prevention Trial-type 1 diabetes. METHODS: Coefficients of variation, intraclass correlation coefficients, and Pearson correlations between the same metabolic tests performed at different times as well as the different tests were determined. RESULTS: Fasting samples on the same day had ...

BACKGROUND: We examined women in their 80s and 90s and evaluated the hypothesis that abnormalities in the dynamic response of glucose and insulin to a glucose load are associated with frailty status. METHODS: We performed a 75 g oral glucose tolerance test in 73 community-dwelling women aged ...

ObjectivesTo determine factors associated with diabetes, insulin resistance, and abnormal glucose tolerance in older men with or at-risk for HIV.MethodsDiabetes was assessed by self-report in 643 men ?49 years old with- or at-risk for HIV. In a subset of 216 men without previously-diagnosed diabetes (including 90 HIV-uninfected men; 28 ...

The aim of this study was to compare the causes of death and parameters related to alcohol consumption, between subjects diagnosed as diabetic, clinically by their general practitioner, or glucose intolerant and in particular as diabetic, using the epidemiological criteria of an abnormal glucose level following an oral ...

A standard oral glucose tolerance test (OGTT) was administered to 28 adults with Williams syndrome (WS). Three quarters of the WS subjects showed abnormal glucose curves, meeting diagnostic criteria for either diabetes or the pre-diabetic state of impaired glucose ...

BackgroundPreliminary evidence suggests an association between obesity and gut inflammation.AimsTo evaluate the frequency of glucose abnormalities and their correlation with systemic and intestinal inflammation in severely obese children.Patients and MethodsThirty-four children (25 males; median age 10.8 � 3.4 yrs) with severe obesity (BMI >95%) were ...

Fifteen patients who had had a myocardial infarction before the age of 43 were compared with thirteen age-matched normal subjects. Twelve of the patients and three of the controls had a delayed glucose and insulin peak in the glucose and insulin areas than normal curves. When the measurements of the four patients with the largest areas under the ...

BackgroundPregnant women commonly receive screening for gestational diabetes mellitus by use of a 50 g glucose challenge test, followed by a diagnostic oral glucose tolerance test for those whose glucose challenge test result is abnormal. Although women with gestational diabetes have an ...

Glucose, insulin and non-esterified fatty acid (NEFA) metabolism was studied in 18 patients (mean age 49) with ischemic heart disease (IHD) who did not have any concurrent disorder known to affect glucose tolerance. Significant hyperglycemia and hyperinsulinemia were observed in the IHD patients after oral glucose. ...

The intravenous glucose tolerance test, IVGTT, has been used to evaluate patients in whom abnormalities in carbohydrate metabolism and diabetes mellitus are suspected. IVGTT, if analyzed using ``minimal models'', or discrete-time methods, provides information on the sensitivity of glucose disappearance to insulin ...

Of 30 patients with chronic liver disease 16 showed some degree of impairment of glucose tolerance, and 16 patients had lack of suppression of raised fasting growth hormone levels or showed an anomalous rise after oral glucose. No relationship, however, existed between the state of glucose ...

During the oral glucose tolerance test your blood glucose is tested two hours after drinking 75 grams of glucose. You are diagnosed with ...

This report gives the prevalence rates of impaired glucose tolerance (IGT) and diabetes mellitus (DM) for several Micronesian, Polynesian, and Melanesian populations in the Pacific region according to the new WHO criteria.The Micronesian population of Nauru show the highest prevalence rates of both IGT (22.7%) and DM (30.3%) - 53% of the adult population ...

The report on glucose tolerance of adults deals with diabetes prevalence and results of a glucose tolerance test, by age, and sex. The report is based on data from the National Health Survey.

Higher prevalence of both hypertension and obesity in African Americans is associated with a disproportionately greater burden of cardiovascular diseases in this ethnic group. The purpose of this study was to examine whether there is an interaction between hypertension and obesity that significantly increases the expression of metabolic risk factors for cardiovascular disease. Four groups of young ...

This study aimed to compare plasma insulin concentrations across the age-range from childhood to old age in the populations of Nauru and Tuvalu, and to assess their relationship to the incidence of impaired glucose tolerance and diabetes in young Nauruans. The studies, performed in 1975 and 1976, found that Nauru had a higher prevalence of Type 2 ...

BackgroundAbnormal glucose metabolism in HIV-infected patients has largely been attributed to protease inhibitor use. However most studies of glucose metabolism in HIV-infected patients have focused on men or have lacked appropriate controls.MethodsWe assessed factors associated with previously-diagnosed diabetes among 620 midlife ...

Glucagon-like peptide�1 (GLP-1) has a diverse set of peripheral actions which all serve to promote enhanced glucose tolerance, and for this reason it has become the basis for new treatments for type 2 diabetes. In this issue of the JCI, Knauf et al. provide clear evidence that GLP-1 signaling in the CNS is also linked to the control of peripheral ...

BackgroundPatients with acute myocardial infarction and newly detected abnormal glucose regulation have been shown to have a less favourable prognosis compared to patients with normal glucose regulation. The importance and timing of oral glucose tolerance testing (OGTT) in patients with acute ...

... CORTISONE ORAL GLUCOSE TOLERANCE RESPONSES IN HEALTHY YOUNG ADULT MALES CLASSIFIED AS TO ORAL HEALTH STATUS,. ...