Background? Guidelines concerning biological treatment of patients with psoriasis recommend different pretreatment and monitoring laboratory panels in variable frequencies to monitor treatment. Objectives? To investigate the relevance of laboratory investigations in monitoring patients with psoriasis on etanercept or adalimumab. Methods? A prospective ...

... congenital acetabular retroversion, developmental dysplasia of ... as well as any abnormality resulting in ... 5) The chondral abnormalities resulting from ...

Controlled laboratory experiments were carried out on samples or bar stock of air- and vacuum-melted Waspalloy, Inconel X-550, and Nimonic 80A alloys to find conditions of heating and hot-working which resulted in abnormal grain growth. These experiments were mainly limited to normal conditions of heating for hot-working and ...

In the past there have been articles indicating that the excretion percentage of Co/sup 60/-tagged B/sub 12/ may be abnormal by as much as 13%. The distribution of results in our relatively large series would imply that only patients excreting 2% or less are definitely abnormal. Those excreting 3 to 4% are a border-line group ...

FREQUENTLY ASKED QUESTIONS FAQ161 GYNECOLOGIC PROBLEMS [PDF format] Understanding Abnormal Pap Test Results What is a Pap test? What causes abnormal Pap test results? ...

Background & AimsLiver disease is a major cause of morbidity and mortality among HIV-infected persons. We evaluated the prevalence, etiology, and factors associated with liver dysfunction in patients during the highly active antiretroviral therapy (HAART) era.MethodsWe performed tests for liver function (baseline and after a 6-month follow-up period) in HIV-infected patients treated at a large ...

Investigation of 92 patients with discoid lupus erythematosus, manifested initially by localized cutaneous lesions only, showed abnormal laboratory test results for 57 patients (62%) on admission and for 62 patients (67.4%) on review 16 to 20 years later. Patients with discoid lesions confined to the head and neck (DLE) showed fewer ...

Our objective was to determine the yield and cost of standardized laboratory testing of HIV-infected patients entering medical care after testing positive for HIV. An HIV staging and referral clinic in a municipal public hospital was our site for a cross-sectional study, and 308 patients were evaluated in the clinic between February 1, 1990 and October 1, 1991. Patients ...

... of miscarriage in the first trimester is a chromosomal abnormality in the fetus. This is usually results from ...

Clinicians order laboratory tests to diagnose, monitor, and screen for diseases, to evaluate or confirm previously abnormal results and to develop prognoses. The rigorous quality assurance programs, large automated processes and economic constraints may induce direct challenges to tailored diagnosis. Clinicians will have to gain an ...

... If the result is normal, is damage absent? � If the result is abnormal, is damage present? ... with abnormal ERG and damage, confirmed by other method ...

The micronucleus and nuclear abnormalities assays have been used increasingly to evaluate genotoxicity of many compounds in polluted aquatic ecossystems. The aim of this study is to verify the efficiency of the micronucleus assay and nuclear abnormality assay in field and laboratory work, when using erythrocytes of the tropical marine ...

At the end of August 2008, many areas in Japan were hit by concentrated downpour. Okazaki City, Aichi, where our hospital is located, suffered serious damage, including two fatalities. The resulting flooding inundated Okazaki City Hospital. Hospital functioning did not stop, but some devices were damaged by the water. There was no direct damage to the clinical ...

Research on psychopathy in women has generated equivocal laboratory findings. This study examined the performance of psychopathic women in 2 laboratory tasks designed to assess abnormal selective attention associated with response modulation deficits: a computerized picture�word (PW) task, and a picture�word Stroop (PW Stroop) ...

The results of automated multiphasic health testing (AMHT) were evaluated with special attention to diagnoses made by physicians and to false positive results, as well as to laboratory test results. The study population consisted of 1,157 patients at the Health Evaluation Center of the Public Health Service ...

A color-vision test battery that will classify personnel according to the severity of their color vision abnormality is recommended for use at Sandia National Laboratories. These tests will result in improved job placement of color-vision-deficient personnel and thereby reduce the possibility of job discrimination without adversely ...

... PSYCHOLOGICAL TESTS, PSYCHOMETRICS, ABNORMAL PSYCHOLOGY, MILITARY PSYCHOLOGY, CLINICAL PSYCHOLOGY, NORMALITY. ...

BackgroundArray CGH has recently been introduced into our laboratory in place of karyotype analysis for patients with suspected genomic imbalance. Results require confirmation to check sample identity, and analysis of parental samples to determine inheritance and thus assess the clinical significance of the abnormality. Here we ...

Twenty-two adults with chronic fatigue were studied to determine the clinical usefulness of commonly applied laboratory tests. Subjects with the chief complaint of fatigue persisting for more than one year were followed for an average of seven months at a university family health centre. During this time a group of commonly recommended tests were carried out and the patients ...

The results of studies on a case of tick paralysis in a female child are described. The patient was paralysed by a single female specimen of Dermacentor andersoni Stiles attached to the left temporal area of the scalp. Paralysis of the lower limbs, incoordinate respiration and weakness of the arms were evident. The findings on physical examination and the ...

Alcohol dependence is often seen in a variety of clinical settings and requires attention to reduce medical complications, set up appropriate treatments, and minimize utilization of healthcare resources. Patient responses to questionnaires are often used to screen for alcohol problems, but can be misleading in the context of altered mental states or in a patient hesitant to disclose a pattern of ...

Quantitative measurements of cerebral blood flow (CBF) by xenon-133 ({sup 133}Xe) tomography, together with magnetic resonance imaging (MRI), electroencephalography (EEG), psychometric tests, and laboratory analyses were performed on 18 human immunodeficiency virus 1 (HIV-1) seropositive asymptomatic subjects. Abnormalities of cerebral perfusion were ...

... A genetic abnormality results in abnormal transport of amino acids in the kidney. The high levels of the amino acid cystine in the urine lead to stone ...

in tetralogy of Fallot and how abnormal cardiovascular development leads to this abnormality and its resulting

... Centrosome abnormalities may result in missegregation of ... significant correlation between centrosome abnormality and chromosome instability ...

Blood samples were obtained from 32 wolf (Canis lupus) pups live-trapped over a three-year period in northern Minnesota. The results of 21 laboratory analyses of hematology and blood chemistry are tabulated and analyzed in terms of study area, age, sex, and year of co11ection. Mean values are compared to those reported for dogs in the same age group. ...

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 4-year-old girl with a constitutional ring chromosome 22 abnormality has been suffering from occasional episodes of morning emesis. Visitors are given both the microscopic description and imaging studies, and are given the opportunity to diagnose the patient. This is an excellent ...

Traditionally, thyroid imaging has been performed primarily using radionuclide scanning. High-resolution computed tomography (CT) was performed in 18 patients to evaluate the CT appearance of various thyroid abnormalities including diffuse toxic goiter, multinodular goiter, Hashimoto thyroiditis, thyroid adenoma, and malignant thyroid tumors. CT images of the thyroid were ...

There is a wide range of clinical problems, from the relatively common to the extremely rare, that result from alterations in the chromosome complement. These numerical and structural abnormalities of the chromosomes can be detected readily by cell culture and analysis in the cytogenetics laboratory, and the chromosome complement is ...

Hydroa vacciniforme (HV) is a rare and chronic pediatric disorder that is characterized by photosensitivity and recurrent vesicles that heal with vacciniforme scarring. The pathogenesis of HV is unknown; no chromosome abnormality has been identified. HV patients have no abnormal laboratory results, so the diagnosis ...

A desert tortoise (Gopherus agassizii) was trapped underground without food or water for nearly 11 mo near Yucca Mountain, Nevada (USA). Physical abnormalities included weight loss, sunken eyes, and muscle atrophy. Biochemical abnormalities determined from blood sampling included marked azotemia and hyperosmolality, which were attributed largely to ...

Ongoing spirometry quality standards are difficult to bring into the daily routine of general practice. As a result, spirometry is rarely performed by primary care physicians. A new approach is proposed: exclusion spirometry. Acceptable and reproducible results are sought. However, the goal of the test is to try to reach values within normal limits, even ...

The study was undertaken to define in a quantitative nonjudgmental technical manner the abnormal environments to which a large package (total weight over 2 tons) would be subjected as the result of a transportation accident. Because of this package weight, air shipment was not considered as a normal transportation mode and was not included in the study. ...

This study evaluated the application of positive reinforcement training (PRT) as an intervention for abnormal behaviors in singly housed laboratory rhesus macaques at 2 large primate facilities. Training involved basic control behaviors and body-part presentation. The study compared baseline behavioral data on 30 adult males and 33 adult females compared ...

Electroencephalographic abnormalities in the absence of any other major laboratory or imaging findings are a frequently encountered phenomenon in many psychiatric disorders. In some cases, clear-cut interictal epileptiform EEG abnormalities in patients with classic primary psychiatric disorders lead to referrals to epilepsy departments ...

Cytogenetic investigations for diagnostic purposes were performed on 1000 first trimester samples of chorionic villi (CVS) in two laboratories using similar techniques. Fetal karyotyping was the primary indication for CVS in 912 and maternal age was the major indication in 758 of them. The risk category "previous child/fetus with chromosome abnormality" ...

BackgroundConvergent evidence implicates white matter abnormalities in bipolar disorder. The cingulum is an important candidate structure for study in bipolar disorder as it provides substantial white matter connections within the corticolimbic neural system that subserves emotional regulation involved in the disorder.AimsTo test the hypothesis that bipolar disorder is ...

Coagulation abnormalities are common in severe pneumonia and sepsis, yet little is known about the presence of coagulopathy or its significance in patients with lesser illness severity. We examined coagulation abnormalities in 939 subjects hospitalized with community-acquired pneumonia (CAP) in 28 US hospitals, hypothesizing that ...

PurposeTo propose an alternative hypothesis for the observed differential survival of patients with small, medium, and large choroidal melanomas based on recently uncovered cytogenetic evidence about melanocytic choroidal tumors.MethodsReview and analysis of published data.ResultsRecent evidence has shown that recurring nonrandom cytogenetic abnormalities ...

diseases, such as gonorrhea and chlamydia. Normal Results A negative culture, or no growth appearing in the culture, is normal. What Abnormal Results Mean Abnormal results...

AbstractObjectiveThe aim of this study was to investigate the prevalence of clinical and laboratory metabolic abnormalities during long-term risperidone treatment in children and adolescents.MethodsMedically healthy 7- to 17-year-old children chronically treated, in a naturalistic setting, with risperidone were recruited through child psychiatry clinics. ...

BackgroundWe evaluated cytogenetic results occurring with first trimester pregnancy loss, and assessed the type and frequency of chromosomal abnormalities after assisted reproductive treatment (ART) and compared them with a control group. We also compared the rate of chromosomal abnormalities according to infertility causes in ICSI ...

The study objective was to analyse the utility of laboratory tests performed in 30 patients with B-cell chronic lymphocytic leukaemia (B-CLL) at different clinical stages. Laboratory tests included automated and microscopic assessment of peripheral blood and bone marrow counts as well as evaluation of leukaemic cells. Apart from the diagnostic and ...

Mucocutaneous bleeding is common in childhood and may be the result of primary hemostatic disorders such as vascular abnormalities, von Willebrand disease, thrombocytopenia, and platelet dysfunction. A detailed bleeding history and physical examination are essential to distinguish between normal and abnormal bleeding and to decide ...

Primary osteoma cutis in a 24-year-old white woman presented as a small hard tumor beneath the skin of the left breast. Histologic examination of the lesion showed typical osteoma cutis. This was likely to be a case of primary osteoma cutis since the history and results of physical examination and laboratory tests failed to reveal other ...

This work demonstrates the feasibility of OCT for identifying early osteoarthritic pathology. In addition to structural abnormalities, changes in collagen fiber organization, an indicator of very early osteoarthritis, were assessed with a polarization sensitive OCT system. A portable, real time, modular OCT system, suitable for both laboratory and clinical ...

Infectious hepatitis is often the initial suspect when abnormal serum liver function test results are discovered in primary care settings. However, noninfectious liver disorders may also present with altered liver function tests. Noninfectious liver disorders require careful assessment of patient history, physical findings, and serum ...

BackgroundNotifying clinicians about abnormal test results through electronic health record (EHR) -based "alert" notifications may not always lead to timely follow-up of patients. We sought to understand barriers, facilitators, and potential interventions for safe and effective management of abnormal test result ...

Although veterinary clinicians commonly rely on panels of laboratory tests with individual results flagged when abnormal, care should be taken in interpreting normal test results as well. There are several examples of this in evaluating patients with endocrine disease. The finding of a normal leukogram (absence of ...

Background For patients with critical laboratory abnormalities, timely clinical alerts with decision support could improve management and reduce adverse events. Methods The authors developed a real-time clinical alerting system for critical laboratory abnormalities. The system sent alerts to physicians as text ...

(XY), written as 46, XY What Abnormal Results Mean Abnormal results may be due to a genetic syndrome or condition, such as: Down syndrome Klinefelter syndrome Philadelphia...

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 3-week-old baby girl has been brought to the hospital with weight loss and poor appetite. Visitors are given both patient history and laboratory findings, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to ...

... of constitutional chromosome abnormalities using arrays of bacterial ... and sequence variations among laboratory mice using BAC array CGH. ...

Fluorescence in situ hybridization (FISH) provides an important adjunct to conventional cytogenetics and molecular studies in the evaluation of chromosome abnormalities associated with hematologic malignancies. FISH employs DNA probes and methods that are generally not Food and Drug Administration-approved, and therefore, their use as analyte-specific reagents involves unique ...

Quantitative fluorescent PCR (QF-PCR) has been used by many laboratories for prenatal diagnosis of the most common aneuploidies. QF-PCR is rapid, cost-effective, and suitable for automation and can detect most abnormalities diagnosed by conventional karyotyping. Whether QF-PCR should be used alone in most of the samples and in which karyotyping should also ...

Chromosome abnormalities are one of the main causes of congenital defects, and establishing their frequency according to the different clinical indications for invasive procedure during pregnancy is especially important for genetic counselling. We analyzed the results of 29,883 amniotic fluid samples referred to our laboratory for ...

Lipoprotein X (Lp-X) is an abnormal lipoprotein which may form in patients with intra- and extra-hepatic cholestasis. The presence of very high levels of Lp-X has been shown to be a rare cause of pseudohyponatremia. We present a patient with severe obstructive cholestasis secondary to pancreatic cancer leading to very high Lp-X concentrations resulting in ...

Lenalidomide is an antiangiogenic drug associated with hypothyroidism. We describe a case-series of lenalidomide use in hematological cancers and the prevalence of thyroid abnormalities. We reviewed medical records of patients treated with lenalidomide at a single center form 2005 to 2010 and extracted demographic, clinical, and laboratory data. Of 170 ...

We have evaluated the results of clinical and morphological study of microcirculation and its intravascular factors in 120 patients with chronic obstructive pulmonary diseases (COPD). Conjunctival biomicroscopy with quantitative evaluation of microcirculatory changes we performed. This data were compared with the results of laboratory ...

BackgroundAutism is a behavioral disorder with impaired social interaction, communication, and repetitive and stereotypic behaviors. About 5�10 % of individuals with autism have 'secondary' autism in which an environmental agent, chromosome abnormality, or single gene disorder can be identified. Ninety percent have idiopathic autism and a major gene has not yet been ...

Stevens Institute of Technology has established a new Maritime Security Laboratory (MSL) to facilitate advances in methods and technologies relevant to maritime security. MSL is designed to enable system-level experiments and data-driven modeling in the complex environment of an urban tidal estuary. The initial focus of the laboratory is on the threats ...

Hemochromatosis is an autosomal recessive disorder that causes abnormal absorption of iron and results in iron overload. This disorder affects the liver, pancreas, heart, and endocrine systems, and if undetected and untreated, organ damage and death can result. The recent discovery of the gene associated with hemochromatosis has led to ...

The paper gives results of a series of 12 tests for 3 coals from a rural area of China with abnormally high lung cancer rates, a U. S. coal, and pine wood fuel. It also discusses a residential combustion simulator, built at EPA's Research Triangle Park, NC, facility to conduct em...

Unexpected and confusing laboratory test results can occur if a blood sample is inadvertently collected following a blood transfusion. A potential for transfusion-acquired hemoglobinopathy exists because heterozygous individuals show no significant abnormalities during the blood donor screening process. Such spurious ...

Tetralogy of Fallot is a birth defect of the heart consisting of four abnormalities that results in insufficiently oxygenated ...

... the placenta peels away from the uterine wall Chromosomal abnormalities resulting from defects in the sperm or egg ...

... needed. Abnormal apoptosis may result in cancer and neural degenerative diseases such as Alzheimer's disease. Caspases ...

Tetralogy of Fallot is a birth defect of the heart consisting of four abnormalities that results in insufficiently oxygenated ...

A change in the heart's normal electrical conduction system can result in an arrhythmia or irregular heartbeat. An arrhythmia can be an abnormally slow ...

Abnormalities of the skeletal and urogenital system are discussed which result from an interference with the metabolism of calcium in cadmium workers.

to look for signs of transplant rejection. It may also be done on those with high blood pressure to check differential kidney function. What Abnormal Results Mean Abnormal...

The purpose of the CEMAS workshop and the resulting document is to provide a foundation of systematic classification of primary eye movement abnormalities and strabismus conditions that can be utilized for clinical research. The delineation of inclusion a...

Results for abnormal states in nuclear matter are reviewed and compared with pi exp - condensates in the context of chiral invariance and the sigma model. The relative importance of symmetry breaking and conserving interactions is assessed for the two pro...

Rationale and ObjectivesTo assess whether or not prevalence levels affected the confidence ratings of readers during the interpretation of cases in a laboratory ROC type observer performance study.Materials and MethodsWe re-analyzed a previously conducted observer performance study that included 14 readers and 5 different levels of prevalence. The previous study yielded the ...

Seventy-five selective terminations, based on abnormal laboratory findings at first-trimester CVS, were performed in 1581 consecutive pregnancies. In all cases a (semi-) direct method of cytogenetic analysis was used. The 75 abortions were analysed in number of ways. Confirmatory studies showed that three cases had to be considered as false-positive ...

Laboratory bioassays consisting of sediments spiked with three concentrations (30, 130, and 260 microg g-1 As dry wt) of arsenic (As+3) were used to assess morphologic responses and growth in Chironomus tentans larvae. Chironomid larvae were raised in contaminated sediments from egg stage to emergence, and mouthpart abnormalities, larval length, and larval ...

The term "neuroacanthocytosis" describes a heterogeneous group of molecularly-defined disorders which result in progressive neurodegeneration, predominantly of the basal ganglia, and erythrocyte acanthocytosis. The clinical presentation of neuroacanthocytosis syndromes typically involves chorea and dystonia, but a range of other movement disorders may be seen. Psychiatric and ...

an older person What Abnormal Results Mean Lumbosacral spine x-rays may show: Abnormal curves of the spine Abnormal wear on the cartilage and bones of the lower spine, such as bone...

Figure 4a) and capitalized abnormal growth in accounting earnings if y� is capitalized forward accounting� is capitalized abnormal eamings growth, y is (one plus) change in abnormal eamings growth, and the abnormal of the abnormal eamings growth model.^ This form highlights growth in ...

test results. What Abnormal Results Mean Abnormal results may be a sign of infection by bacteria, virus, or fungus. The test results may reveal which specific organism is causing...

The results of bone scanning with the newer technetium-99m complexes were correlated with clinical, laboratory, and radiographic findings in 26 patients with malignant lymphoma (10 with Hodgkin's disease and 16 with non-Hodgkin's lymphomas). Abnormalities on bone scan compatible with lymphomatous involvement of the ...

Objective: The purpose of this review is to present the complex underlying pathophysiology that can form the basis of this common condition. Methods: More than 20 years of clinical experience in endocrinology and plastic surgery and a review of the English-language literature were used to form the basis of this review. Results: While idiopathic and physiologic causes are ...

American toad tadpoles (Bufo americanus) were exposed to malathion and nitrate in a fully factorial experiment that crossed four concentrations of malathion ranging between 0 and 1,000 �g malathion/L, and five concentrations of nitrate ranging from 0 to 16 mg NO(3) -N/L to identify single and interactive effects. In this 21-d experiment, we recorded tadpole length, mass, survivorship, and ...

...disease. (1) Pathology report of tissue biopsy; (2) If laboratory or radiographic tests exist: (i) Abnormal plasma creatinine values; (ii) Abnormal glomerular filtration rate (by either measured creatinine or iothalamate clearance...

...disease. (1) Pathology report of tissue biopsy; (2) If laboratory or radiographic tests exist: (i) Abnormal plasma creatinine values; and (ii) Abnormal glomerular filtration rate (by either measured creatinine or iothalamate...

...demonstrable phenomena that indicate specific psychological abnormalities, e.g., abnormalities of behavior, mood, thought, memory, orientation, development, or perception. They must also be shown by observable facts that can be medically described...

...demonstrable phenomena that indicate specific psychological abnormalities, e.g., abnormalities of behavior, mood, thought, memory, orientation, development, or perception. They must also be shown by observable facts that can be medically described...

Follow-up of abnormal ambulatory laboratory results is often suboptimal. The impact of an ambulatory electronic health record (EHR) on follow-up of markedly elevated blood potassium (K( +)) results was investigated via a retrospective medical record review-before and after EHR implementation-of patients at an adult ...

This update (version 2) of the Terminology of developmental abnormalities in common laboratory mammals (version 1) by Wise et al. [Wise LD, Beck SL, Beltrame D, Beyer BK, Chahoud I, Clark RL, Clark R, Druga AM, Fueston MH, Guittin P, Henwood SM, Kimmel CA, Lindstrom P, Palmer AK, Petrere JA, Solomon HM, Yasuda M, York RG. Terminology of developmental ...

Clinical usefulness of Essential Laboratory Tests (1), proposed by Japan Society of Clinical Pathology, was retrospectively evaluated in 500 outpatients who first visited the medical clinic of a prefectural general hospital. Sixty percent of the patients were diagnosed with gastrointestinal disease or respiratory disease. Performance rates of urinalysis, blood counts, serum ...

The condition of hereditary hemochromatosis (HH) is caused by gene-dependent protein abnormalities involved in iron absorption, storage, or modulation of iron; these abnormalities result in iron overload. The clinical laboratory plays a significant role in case finding, diagnostic validation, and monitoring HH ...

Holoprosencephaly (HPE) is the most common malformation of the human forebrain. When a clinician identifies a patient with HPE, a routine chromosome analysis is often the first genetic test sent for laboratory analysis in order to assess for a structural or numerical chromosome anomaly. An abnormality of chromosome number is overall the most frequently ...

Holoprosencephaly (HPE) is the most common malformation of the human forebrain. When a clinician identifies a patient with HPE, a routine chromosome analysis is often the first genetic test sent for laboratory analysis in order to assess for a structural or numerical chromosome anomaly. An abnormality of chromosome number is overall the most frequently ...

We investigated the prevalence of abnormal screening results (questionnaire and testing for other causes of oligo-ovulation, male or tubal factor infertility) in a group of 1,313 oligo-ovulatory women (included and excluded subjects) screened for inclusion in the PPCOS Trial, a multicenter clinical trial conducted at 13 sites in the USA. Other than failure ...

The investigation of children with suspected inherited platelet disorders is challenging. The causes of mucocutaneous bleeding are many, and specialized testing for platelet disorders can be difficult to access or interpret. An algorithm developed for the investigation of suspected platelet disorders provides a sequential approach to evaluating both platelet function ...

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 67-year-old woman has presented to the hospital for a radical hysterectomy for endometrial carcinoma. Visitors are given the immuohematological findings, including patient charts, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences ...

Although the biosynthetic pathway to heme has been well elucidated and errors along that route have been identified and firmly connected to specific diseases, the porphyrias, slight but nonspecific abnormalities, are occasionally invoked as proof of porphyria or in support of other diagnoses. An errant patient with a conundrum of symptoms but without an explanation for them ...

This report provides computational evaluation results demonstrating that mixed oxide waste can be safely stored in Intercell Storage Wells 2 and 3 of Building 3019 at the Oak Ridge National Laboratory. Existing, verified computational techniques are validated with applicable critical experiments and tolerance limits for safety analyses are derived. ...

Acute lead poisoning can present a difficult diagnostic dilemma, with symptoms that mimic those of hepatitis, nephritis, and encephalopathy. The authors report two cases in intravenous methamphetamine users who presented with abnormal liver function values, low hematocrit values, basophilic stippling of red blood cells, and elevated blood lead levels. Both patients excreted ...

Acute fatty liver of pregnancy (AFLP) is a rare, potentially fatal complication that occurs in the third trimester or early postpartum period. Although the exact pathogenesis is unknown, this disease has been linked to an abnormality in fetal fatty acid metabolism. Early diagnosis of AFLP sometimes can be difficult because it shares features with other common conditions such ...

Hereditary paroxysmal ataxia is a rare dominantly inherited disorder characterized by recurrent attacks of cerebellar ataxia, dysarthria, and nystagmus. Each attack lasts from several minutes to few hours or days. Usually there are no motor difficulties between attacks. We report a patient who had had recurrent ataxic episodes since early childhood. Four members of the family over two generations ...

The Diagnostic Pathfinder was designed to help students learn diagnostic problem solving by supporting them in explaining relationships among history and physical examination findings, data abnormalities, and the underlying mechanisms of disease. The Pathfinder has been used to teach diagnostic problem solving to veterinary students since 2001 and is currently in use at 10 ...

Abnormal thyroid function test results are common among human immunodeficiency virus (HIV)-infected patients. Although the prevalence of overt thyroid disease does not appear to be significantly increased in HIV-infected patients, compared with the general population, specific patterns of abnormal thyroid function test findings are ...

Great blue heron hatchlings from colonies in the Strait of Georgia, British Columbia, Canada are being monitored for environmental contaminant exposure and effects by the Canadian Wildlife Service. The contaminants of concern are polychlorinated dibenzodioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), primarily derived from kraft pulp mill effluent. The levels of PCDDs and PCDFs in eggs ...

Churg-Strauss syndrome (CSS) is a rare systemic vasculitis, almost invariably accompanied by asthma, nasal polyposis, paranasal sinus abnormalities, and increased peripheral blood eosinophil count. Neurological involvement as peripheral neuropathy is a common feature, whereas cerebral involvement is extremely rare. Herein, we report the case of a young man who presented with ...

This paper reports a new dysfibrinogenemia with an unusual pattern of laboratory assays. The patient, a 51-year-old female with a lifelong moderate bleeding history, was initially diagnosed with von Willebrand disease based on routine coagulation assays and the clinical bleeding presentation. During recent testing as part of a preoperative screen and without any current ...

Quality-assured, comprehensive, cytology-based population screening programmes have resulted in a substantial decline in the incidence of, and mortality from, cervical cancer. Cytology classification systems divide squamous cell abnormalities into low grade and high grade. Women with high-grade squamous abnormalities, cytology ...

Abnormal liver test results indicate underlying liver disease; unfortunately, these tests are neither sensitive nor specific. The pattern of liver test abnormality can identify the cause and can direct further investigations. Abnormal test results should be followed by a thorough history, which ...

Background:Upper respiratory tract problems, eg, acute sinusitis are frequently occurring illnesses in returned travelers. The most accurate and cost-effective method for diagnosing these upper respiratory tract illnesses in hospital-based settings remains an area of uncertainty. In the present retrospective cohort study, the usefulness of routine sinus radiography in the diagnostic work-up of ill ...

Myocardial perfusion single-photon emission computed tomography (SPECT) has been extensively applied in the clinical assessment of patients with diabetes mellitus. The aim of the present study was to evaluate stress technetium-99m sestamibi SPECT MPI perfusion in silent myocardial ischemia and its association with some clinical and laboratory parameters in an asymptomatic ...

Use of pesticides and other agro-chemicals adversely influence amphibians either directly by killing them or by inducing sublethal, chronic effects. Many studies have investigated the effect of mixtures of pesticides or fertilizers. We studied the combined effects of nitrate and malathion ([(dimethoxy phosphino thioyl] butanediotae) on the early growth, expression of ...

PURPOSE: Approximately 8% of couples attempting to conceive are infertile and male infertility accounts for approximately 50% of infertility among couples. Up to 25% of males with non-obstructive infertility have chromosomal abnormalities and/or microdeletions of the long arm of the Y-chromosome. These are detected by conventional chromosome and Y-microdeletion analysis. In ...

From fifth symposium on engineering problems of fusion research; Princeton, New Jersey, USA (6 Nov 1973). It appears that, when considering the field limits of toroidal superconducting magnets, the mechanical stresses on the coils will be a primary limitation. The results of a detailed analysis of the forces and resultant stresses imposed on the ...

Six cytogenetics laboratories joined in a collaborative study of rat chromosome aberrations to measure interlaboratory variation in results of standardized procedures and to devise methods to minimize interlaboratory differences. A preliminary workshop was held to resolve scoring differences, to develop a joint protocol and common glossary, and to reach ...

The association of intrauterine exposure to diethylstilbestrol (DES) and the subsequent development of reproductive tract abnormalities in young women has been well documented. Although the incidence of vaginal adenocarcinoma was low in the exposed population, vaginal adenosis, a nonmalignant abnormality, was quite common. In order to study the ...

Objective: Platelet count has been proposed as a screening test for generalized coagulopathy in women with preeclampsia. We performed this study to determine the relationship between platelet counts and the risk of abnormal coagulation and adverse maternal outcomes in women with preeclampsia. Methods: We used data from women in the PIERS (Pre-eclampsia Integrated Estimate of ...

The charts of 115 patients presenting to the Ottawa Civic Hospital Emergency Department with abdominal pain were examined for objective signs, laboratory investigations, cost of investigations, and disposition of the patients. After the initial visit, 85 patients were contacted for followup. Of these, 67 percent had no abdominal pain within one week of the initial visit; 33 ...

This paper describes the development of OVERSEER: a prototype knowledge-based system that monitors the drug treatment of psychiatric patients in real time. Using treatment protocols developed by the expert clinician, OVERSEER monitors the drug treatment process and issues alerts when standard clinical practices are not followed or when laboratory results ...

This study used the Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS) data to investigate occurrences reported during one year at Los Alamos National Laboratory (LANL). ORPS provides a centralized database and computerized support for the Collection, distribution, updating, analysis, and validation of information in occurrence reports about ...

Children with sickle cell anemia are at risk for brain injury. Physicians obtain brain magnetic resonance imaging (MRI) for clinical indications to determine if a patient has developed a brain injury. Controversy exists whether all children with sickle cell anemia should undergo MRI screening. This retrospective study evaluates the clinical and laboratory correlates for brain ...

, or clinodactyly), and craniofacial abnormalities (lip/palate clefting, micrognathia, hypertelorism, exophtalmos

page to a friend Share Pleural fluid smear is a laboratory procedure to check for bacteria, fungi, or abnormal cells in the fluid that may be found in the space around the...

Jun 3, 2009 ... On Earth, abnormally warm, dry weather periods in late autumn occur when low- pressure systems are blocked in the winter hemisphere. ...

Jun 3, 2009 ... On Earth, abnormally warm, dry weather periods in late autumn occur when low- pressure systems are blocked in the winter hemisphere. ...

... as a markedly abnormal laboratory test value according ... for an unscheduled follow-up chemistry lab testing. ... time the liver function tests were normal ...

Jan 12, 2010 ... Development of appropriate methodologies for sampling gypsy moth populations in ... Pupal abnormalities among laboratory-reared gypsy moths. ...

... but were rather casualties of starvation caused by developmental abnormalities (C. van Oosterhout, pers. observ.). Were these individuals ... ...

A regional laboratory for the diagnosis and investigation of hemoglobinopathies was established by the Hamilton District Program in Laboratory Medicine in October 1970. Specimens from patients suspected of having a hemoglobinopathy were referred to the regional laboratory from all the hospitals participating in the program. Between ...

... M. Yasuda, R. G. York. 1997. Terminology of developmental abnormalities in common laboratory mammals (Version 1). Teratology 55: ... ...

Formal transformation of equations (2) is made by defining certain integral .... Sonin, A. A.: The Behavior of Free Molecular Cylindrical Langmuir Probes in ...

On Earth, abnormally warm, dry weather periods in late autumn occur when low- pressure systems are blocked in the winter hemisphere. ...

in stamen hairs, pollen abortion, microspore death, disturbed spindle function, and total chromosome abnormalities. In the Neurospora crassa, ...

The Third International Society of Blood Transfusion Workshop on Molecular Blood Group Genotyping was held in 2008, with a feedback meeting at the International Society of Blood Transfusion Congress in Macao SAR, China. Thirty-three laboratories participated, eight less than in 2006. Six samples were distributed: sample 1 representing DNA from a sample referred because of ...

An evaluation, calibration and assessment of the Eberline SPING-3 ATR stack effluent monitor was conducted. This unit which monitors particulate, iodine and noble gas effluents was producing abnormal results following the initial installation and operational testing. The purposes of this work were to find the causes of the abnormal ...

Autosomal chromosome aneuploid pregnancies that survive to term, namely, trisomies 13, 18, and 21, account for 89% of chromosome abnormalities with a severe phenotype. They are normally detected by full karyotype analysis of cultured cells. The average reporting time for a prenatal karyotype analysis is approximately 14 days, and in recent years, there has been increasing ...

Over the last decade, fluorescence in situ hybridization (FISH) has become a firmly established technique in the diagnosis and assessment of lymphoid malignancies. However, this technique is not wide-ly used in the routine diagnostic evaluation of paraffin-embedded biopsies, most likely because of a perception that it is technically more demanding. There are also uncertainties regarding diagnostic ...

The androgen receptor (AR) is a high affinity receptor protein encoded on the human X-chromosome that mediates the actions of androgens during development and in the adult. Defects in this receptor protein result in a wide range of abnormalities of male sexual development. Studies in a number of different laboratories have identified ...

Fabry disease is a rare X-linked lysosomal storage disorder caused by deficient activity of alpha-galactosidase A (alpha-Gal A) resulting in the storage of glycosphingolipids, especially globotriaosylceramide (Gb3), in cells throughout the body, causing life-threatening renal, cardiac, and cerebrovascular complications in hemizygous males and some heterozygous females. Disease ...

A massive transfusion protocol (MTP) in which most non-RBC transfusions were laboratory result-driven was updated to a 1:1:1 RBC/plasma/platelet formula-driven protocol. Platelet count, fibrinogen level, and prothrombin time (PT) were monitored. In the patients who survived the first 12 hours, the results of coagulation tests were ...

The endocrine laboratory must provide accurate and timely results for the critically ill patient. A number of pathophysiological factors affect assay systems for adrenal, thyroid and gonadal function tests. The effects are primarily on estimates of 'free hormone' concentration through abnormal binding protein concentrations and the ...

PurposesTo investigate the frequencies of AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China. Moreover, to compare the prevalence of these abnormalities with other countries and regions in the world.Methods305 infertile men were enrolled. A complete semen analysis and reproductive hormones were measured according to ...

Background/Aims:The objective of this study was to describe patients with chronic diarrhea and abnormal skin hyperpigmentation with distinct distribution.Methods:This is a retrospective review of children who presented with diarrhea and skin hyperpigmentation. The clinical presentation, laboratory investigations as well as endoscopic and histological data ...

Connective tissue diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis, Sj�gren's syndrome, and scleroderma are systemic disorders that may have an autoimmune basis. The system manifestations vary, and there is frequent overlap among the syndromes. Liver involvement in patients with connective tissue diseases has been well documented but is generally considered rare. ...

Sandia National Laboratories (SNL) is actively engaged in research to characterize abnormal environments, and to improve our capability to accurately predict the response of engineered systems to thermal and structural events. Abnormal environments, such as impact and fire, are complex and highly nonlinear phenomena which are difficult ...

Fourteen children with Epstein-Barr virus (EBV) encephalitis admitted to our pediatric department during the period 1988 to 1998 were collected and reviewed to characterize the clinical, laboratory and neuroradiological findings. There were 7 boys and 7 girls. The age of onset ranged from 10 months to 14 years. Among them, 5 patients belonged to Alice in Wonderland syndrome, 5 ...

HPV Testing Shows Which Pap Abnormalities Need Attention Testing for the human papillomavirus (HPV) may help doctors and patients decide what to do about the mildly abnormal and very common Pap test result known as ASCUS. Findings from a major, randomized, multicenter study by the National Cancer Institute (NCI) show that HPV testing ...

pathological condition occurred. As a result, they may classify diabetes as an abnormal blood sugar level diabetes as an abnormality in metabolism, and another specialist may classify diabetes as a lifestyle. pathological condition of metabolic disorders is an abnormal state consisting of a metabolic ...

Results for abnormal states in nuclear matter are reviewed and compared with $pi$$sup -$ condensates in the context of chiral invariance and the sigma model. The relative importance of symmetry breaking and conserving interactions is assessed for the two problems. Vacuum self energy effects are crucial in abnormal matter ...

... laceration, traumatic arteriovenous fistula, pleural ... the catheter results in higher thrombosis rates ... Femoral arterial catheters may be safely used if the ...