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1
Portal Hypertension

... Gallbladder Disorders Chapters Manifestations of Liver Disease Portal Hypertension Portal hypertension is abnormally high blood pressure in branches of ...

MedlinePLUS

2
Detection of portal venous gas on sonography, but not on CT.
2001-10-24

We report three cases of portal venous gas detected on sonography without any portal abnormality on CT. In such a situation portal gas could correspond to a tiny amount of intraluminal gas after blunt abdominal trauma or, in contrast, to large or very large quantities of high blood-solubility ...

PubMed

3
Pancreatic vascular regulation in chronic pancreatitis in cats.
1995-01-01

In experimental obstructive chronic pancreatitis the normal hyperaemic response to secretory stimulation is lost, suggesting abnormal vascular regulation. Vascular regulatory mechanisms were investigated by observing the effect of increments in portal pressure on pancreatic blood flow in normal cats and cats with chronic pancreatitis. ...

PubMed Central

4
Portal thrombosis: dynamic CT features and course
1985-03-01

Portal thrombosis was diagnosed on computed tomography (CT) in 10 patients and confirmed by sonography. CT demonstrated decreased density of the portal vessels in 9 patients with peripheral arterial concentration of contrast material surrounding the intraluminal thrombus. The involved vessels were generally enlarged. Three patients had follow-up scans, ...

Energy Citations Database

5
Opinions Can Specialized Pathogens Colonize

causing pronounced enlargements in the liver and spleen, and abnormalities in blood flow through flukes, though, by being dioecious (having separate male and female worms) and dimorphic (with the two]. Nutrients are then conveyed to the liver via the hepatic portal system. Most species of schistosomes live

E-print Network

6
Computed tomographic manifestations of abdominal and pelvic venous collaterals
1982-02-01

Obstruction of blood flow through the inferior vena cava and portal vein may produce venous collaterals. These include the paravertebral venous system and its communications with the ascending lumbar veins and azygous/hemiazygous system; gonadal, periureteric, and other retroperitoneal veins; abdominal wall veins; hemorrhoidal venous plexus; and the ...

Energy Citations Database

7
Humoral Mechanism in Pathogenesis of Portal Hypertension.
1982-01-01

The pathogenesis of portal hypertension is not entirely clear. Mechanical obstruction to the portal vascular beds and increase of portal blood flow have been considered important factors implicated in the elevation of portal pressure. Previously the autho...

National Technical Information Service (NTIS)

8
Study of Abnormal Blood Clotting in Children With Stroke
2011-05-05

Abnormalities; Blood Coagulation Disorder; Brain Disease; Cerebrovascular Accident; Vascular Disease

ClinicalTrials.gov

9
Regulation of hepatic blood flow: The hepatic arterial buffer response revisited
2010-12-28

The interest in the liver dates back to ancient times when it was considered to be the seat of life processes. The liver is indeed essential to life, not only due to its complex functions in biosynthesis, metabolism and clearance, but also its dramatic role as the blood volume reservoir. Among parenchymal organs, blood flow to the liver is unique due to ...

PubMed Central

10
[Cholangiopathy associated with portal hypertension.
2011-08-19

Portal cholangiopathy encompasses a group of abnormalities of the biliary system and gallbladder that occur secondary to chronic portal vein thrombosis and collateral venous circulation. Chronic obstruction of the portal vein is a frequent cause of gastrointestinal variceal bleeding, but data on biliary tract ...

PubMed

11
Portal venous infusions of L-glutamine in anaesthetized dogs do not influence renal function.
1992-10-01

It has been reported that the intraportal infusion of glutamine in Munich-Wistar rats will cause depression of renal perfusion and the urinary excretion of salt and water. We have attempted to reproduce these findings in anaesthetized dogs. L-Glutamine was infused at doses between 120 and 150 mumol/min into the portal vein and femoral vein of anaesthetized dogs. No effect was ...

PubMed

12
Radioisotopic flow scanning for portal blood flow and portal hypertension
1987-08-01

The use of a simple, noninvasive, isotope scanning technique for the determination of relative portal blood flow and detection of portal hypertension is described. Using this technique the presence of portal hypertension was demonstrated in seven of nine patients known to have elevated portal ...

Energy Citations Database

13
Regional blood flows by the microsphere method: reproducibility in portal hypertensive rats and influence of a portal vein catheter
1988-04-01

To determine the reproducibility of splanchnic blood flow measurements by the microsphere method in rats with portal hypertension and the effects of laparotomy with portal vein cannulation, eight groups of 10 rats were studied. Microspheres were labelled with /sup 113/Sn or /sup 141/Ce. Laparotomy with portal ...

Energy Citations Database

14
Assessment of intrahepatic blood flow by Doppler ultrasonography: Relationship between the hepatic vein, portal vein, hepatic artery and portal pressure measured intraoperatively in patients with portal hypertension
2011-07-19

BackgroundAbnormality of hepatic vein (HV) waveforms evaluated by Doppler ultrasonography has been widely studied in patients with chronic liver disease. We investigated the correlation between changes in HV waveforms and portal vein velocity (PVVel), the hepatic artery pulsatility index (HAPI), and also the extent of abnormal Doppler ...

PubMed Central

15
Stimulation of insulin secretion by medium-chain triglycerides in patients with cirrhosis 1
1971-02-01

Oral medium-chain triglycerides were given to 10 normal volunteers, 12 cirrhotics (group I) without and 28 cirrhotics (group II) with abnormal portal systemic communications (ascites, splenomegaly, oesophageal varices, or surgically-created portacaval shunts). After 30 ml of medium-chain triglyceride oil there was no appreciable change in serum glucose ...

PubMed Central

16
Brain Blood Flow Abnormalities Persist in Gulf War Vets

... the abnormalities in blood flow in the brain's hippocampus -- the region associated with spatial navigation and the ...

MedlinePLUS

17
Imaging assessment of congenital and acquired abnormalities of the portal venous system.

Abnormalities of the portal venous system are a heterogeneous group of conditions that can cause substantial morbidity and mortality and may lead to complications during surgery or percutaneous interventions involving the portal venous system. High-resolution computed tomography, ultrasonography, and magnetic resonance imaging permit a ...

PubMed

18
Use of transsplenic injection of agitated saline and heparinized blood for the ultrasonographic diagnosis of macroscopic portosystemic shunts in dogs.

We describe the use of ultrasonography-guided percutaneous splenic injection of agitated saline and heparinized blood for the diagnosis of portosystemic shunts (PSS) in 34 dogs. Agitated saline mixed with 1 ml of heparinized autologous blood was injected into the spleen of 34 sedated dogs under sonographic guidance. The transducer was then sequentially ...

PubMed

19
Glutamine prevents gastric oxidative stress in an animal model of portal hypertension gastropathy.
2011-10-01

Background and rationale. Portal hypertension (PHI) is a clinical syndrome characterized by increases of the blood flow and/or of the vascular resistance in the portal system. A direct consequence of PHI can appearance different lesions on the gastric mucosa and submucosa, cumulatively termed portal hypertensive ...

PubMed

20
Transjugular intrahepatic portosystemic shunt (TIPS): MedlinePlus...
2011-08-30

are blockages, blood cannot flow through it very easily. This is called portal hypertension (increased pressure and backup at the portal vein). When this problem happens, you...

Science.gov Websites

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21
The bowel, the genitourinary tract, and infective endocarditis.
1984-03-01

Of 582 episodes of infective endocarditis 75 were attributable to organisms normally resident in the bowel and 12 others were associated with alimentary tract operations, investigations, or disease. The mean age of the 87 patients in this particular group was higher (59.7 years) than that of all the patients with infective endocarditis (51.4 years). As far as could be ascertained 41% had no ...

PubMed Central

22
How to minimize blood loss during liver surgery in patients with cirrhosis.
2009-09-01

Patients with liver disease frequently have substantial changes in their haemostatic system. This is reflected in abnormal test results on routine coagulation screening assays such as the prothrombin time (PT), activated thromboplastin time (APTT) and platelet count. Traditionally, attempts were made to correct abnormalities in the haemostatic system as ...

PubMed

23
How to minimize blood loss during liver surgery in patients with cirrhosis
2009-09-01

Patients with liver disease frequently have substantial changes in their haemostatic system. This is reflected in abnormal test results on routine coagulation screening assays such as the prothrombin time (PT), activated thromboplastin time (APTT) and platelet count. Traditionally, attempts were made to correct abnormalities in the haemostatic system as ...

PubMed Central

24
Relationship of splanchnic blood flow and portal venous resistance to elevated portal pressure in the dog.
1976-02-01

To determine the relationship of splanchnic blood flow and portal venous resistance to elevated portal pressure, in situ perfusion of the splanchnic circuit was carried out in 12 freshly killed dogs at varying perfusion rates and degrees of acute and chronic portal vein constriction. In six normal dogs before being ...

PubMed Central

25
EVALUATION OF PORTAL CIRCULATION BY PERCUTANEOUS SPLENIC ISOTOPE INJECTION
1961-04-01

A technique of splenic isotope injection for the evaluation of portal circulatory dynamics is presented. By tracing circulation to the liver and heart, considerable information can be gained concerning portal hypertension, speed of hepatic blood flow, and the presence of collateral venous return. (auth)

Energy Citations Database

26
Cirrhosis and Portal Hypertension

Cirrhosis and Portal Hypertension What is cirrhosis? In people who have cirrhosis, the cells of the liver are damaged and can�t repair ... your liver. Return to top What is portal hypertension and what causes it? Normally, blood is carried ...

MedlinePLUS

27
Red blood cells, sickle cell (image)

Sickle cell anemia is an inherited blood disease in which the red blood cells produce abnormal pigment (hemoglobin). The abnormal hemoglobin causes ...

MedlinePLUS

28
Red blood cells, multiple sickle cells (image)

Sickle cell anemia is an inherited disorder in which abnormal hemoglobin (the red pigment inside red blood cells) is produced. The abnormal hemoglobin causes red blood ...

MedlinePLUS

29
Portal hypertension as portrayed by marked hepatosplenomegaly: case report
1987-12-01

The liver is vulnerable to as host of disease processes, including portal hypertension. This is a severe hepatic condition in which the liver is subject to numerous imbalances: increased hepatic blood flow, increased portal vein pressure due to extrahepatic portal vein obstruction, and/or increases in hepatic ...

Energy Citations Database

30
Congenital extrahepatic portosystemic shunts (abernethy malformation): a histopathologic evaluation.
2011-09-01

Congenital extrahepatic portosystemic shunt, also known as Abernethy malformation, is a rare malformation in which intestinal and splenic venous blood bypasses the liver and drains into systemic veins. Aside from the complete or near-complete absence of portal veins, other histologic features of Abernethy malformation have not been evaluated in the ...

PubMed

31
Portal hypertensive gastropathy: a review.
2010-06-08

Portal hypertensive gastropathy (PHG) occurs as a complication of cirrhotic or non-cirrhotic portal hypertension. Although the pathogenesis of PHG is not completely understood, evidence suggests that the key factor for the development of PHG is portal hypertension. PHG is clinically important because it may cause acute (and even) ...

PubMed

32
Portal hypertensive duodenal polyp: a case report.
2007-03-01

Abnormalities of gastric mucosa in patients with portal hypertension are well documented. Manifestations of portal hypertension in small bowel and colon are less common. Colonic polypoid lesions microscopically consisting of a normal mucosa, with dilatation of submucosal vessels, have been described. We here report the first case of ...

PubMed

33
Portal biliopathy in a 13-year-old Asian girl: a case report and review of literature.

Portal biliopathy (PB) is a term used to describe biliary ductal and gallbladder wall abnormalities seen in patients with portal hypertension. The pathogenesis of PB is not well known. It has been postulated that external pressure of portal cavernoma and/ or ischemia may play a role. We report a case of a patient ...

PubMed

34
Cruveilhier-Baumgarten disease in a patient with Turner syndrome: case report of a rare indication for liver transplantation.
2008-03-01

Some chromosomal alterations can be associated with vascular abnormalities. For instance, Turner syndrome can be complicated by agenesis or hypoplasia of the portal venous system causing presinusoidal portal hypertension. Liver transplantation to treat this condition overcomes portal hypertension and reconstitutes ...

PubMed

35
Hypotension

What Is Hypotension? Hypotension (HI-po-TEN-shun) is abnormally low blood pressure. Blood pressure is the force of blood pushing against the walls of ...

MedlinePLUS

36
Autoradiographic study of the regional distribution of gastric blood flow in portal hypertensive rats
1989-11-01

This study measures regional gastric blood flow in portal hypertensive rats at three separate periods after portal vein ligation using quantitative autoradiography with 14C-labeled iodoantipyrine. The level of corpus mucosal blood flow was significantly reduced in 3-day portal vein-ligated ...

Energy Citations Database

37
Congenital and acquired abnormalities of the portal venous system: multidetector CT appearances.
2011-06-01

A knowledge of normal anatomy as well as the most frequent variants and abnormalities of the portal venous system are of great importance for liver surgery and interventional procedures. An understanding of the varied MDCT appearances of these abnormalities will allow more definitive diagnoses and help avoid false diagnoses. ...

PubMed

38
Ethanol-induced increase in portal blood glow: Role of adenosine
1988-04-01

The mechanism by which ethanol induces an increase in portal vein blood flow was studied in rats using radiolabeled microspheres. Ethanol by gavage resulted in an increase of 50-70% in portal vein blood flow. The ethanol-induced increase in portal blood flow was suppressed ...

Energy Citations Database

39
Evaluation of inferior mesenteric vein blood flow circulation with per-rectal administration of thallium-201 and technetium-99m pertechnetate
1990-05-01

We administered both per-rectal thallium-201 (201Tl) and technetium-99m pertechnetate (99mTc) to patients with liver diseases in order to understand the abnormalities of inferior mesenteric vein (IMV) blood flow circulation. As 201Tl heart-to-liver uptake ratio (H:L), reflecting the degree of portal-systemic shuntings (PSS), increased, ...

Energy Citations Database

40
Effect of Inflammatory and Noninflammatory Stress on Plasma ...

... and Noninflammatory Stress on Plasma Ketone Bodies and Free Fatty Acids and on Glucagon and Insulin in Peripheral and Portal Blood,. ...

DTIC Science & Technology

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41
CARDIAC AND PERIPHERAL EFFECTS OF DOPAMINE ...
1969-11-25

... endotoxin values during dopamine infusion, which portal ... BLOOD CIRCULATION, PARENTERAL INFUSIONS, CHEMOTHERAPEUTIC AGENTS ...

DTIC Science & Technology

42
Value of duplex doppler ultrasonography in non-invasive assessment of children with chronic liver disease
2010-12-28

AIM: To investigate the value of duplex Doppler ultrasonography (US) in the assessment of the hemodynamics of the portal and hepatic veins in a cohort of children with chronic liver disease (CLD) and to detect any relationship between the US changes, etiology and severity (or stage) of CLD.METHODS: We prospectively enrolled 25 children with biopsy-proven CLD. Thirteen had ...

PubMed Central

43
Liver cirrhosis.
2011-04-01

Liver cirrhosis is a frequent consequence of the long clinical course of all chronic liver diseases and is characterized by tissue fibrosis and the conversion of normal liver architecture into structurally abnormal nodules. Portal hypertension is the earliest and most important consequence of cirrhosis and underlies most of the clinical complications of ...

PubMed

44
Splanchnic hyperemia after liver transplantation in patients with end-stage liver disease.
1998-07-01

Systemic and splanchnic hemodynamic parameters were evaluated in 12 patients with cirrhosis before and 3 and 6 months after liver transplantation. Results were compared with those obtained in 8 healthy subjects. Three months after liver transplantation recipients had an increase in mean arterial pressure (98 +/- 7 v 78 +/- 9 mmHg; P < .05), an insignificant decrease in cardiac index (3. 4 +/- ...

PubMed

45
Urine - abnormal color

Urine of an abnormal color appears different from the usual straw-yellow color. Abnormally-colored urine may be cloudy, dark, or blood-tinged. See also: ...

MedlinePLUS

46
Abdominal MRI scan: MedlinePlus Medical Encyclopedia
2011-08-09

Kidney damage Lymphadenopathy (abnormalities of the lymph nodes) Obstructed vena cava Pancreatic cancer Portal vein obstruction (liver) Renal arterial obstruction Renal vein...

Science.gov Websites

47
Apparently Nonspecific Enzyme Elevations After Portal Vein Delivery of Recombinant Adeno-Associated Virus Serotype 2 Vector in Hepatitis C Virus-Infected Chimpanzees
2008-07-16

AbstractHepatic gene transfer is envisioned as a substitute for protein replacement therapies, many of which are derived from blood products. Thus, the target populations may have a high prevalence of blood-borne pathogens, such as hepatitis C virus (HCV). We sought to determine whether the safety of recombinant adeno-associated virus serotype 2 (rAAV2) ...

PubMed Central

48
Toxicokinetics of Microcystin and Dihydro-Microcystin in ...
1994-05-14

... At 75 micrograms/kg via the ileum, the blood concentration peaked at 90 minutes, and the concentration in portal blood was 3.6 times greater than ...

DTIC Science & Technology

49
The Hypothalamus and Hormonal Activity.
1964-01-01

Contents: The release of luteinizing hormone (LH) in the rabbit; Investigation of the releasing factor content of portal vessel blood; Studies on ovulation in immature rats; A study of the concentration, and activity, of thyrotrophic hormone in blood; TSH...

National Technical Information Service (NTIS)

50
EFFECTS OF DOPAMINE ON THE LIVER BEFORE AND ...
1969-10-27

... blood from the aorta of the donor dog and the portal vein was perfused by blood from the inferior vena cava of the donor dog (Figure I). Transfer of ...

DTIC Science & Technology

51
Abnormal Cells Present in Blood Years before Leukemia Is Diagnosed

Abnormal white blood cells are present years before diagnosis in virtually all patients with a chronic form of lymphocytic leukemia.

Cancer.gov

52
Portal hypertension complicating myelofibrosis: reversal following splenectomy.
1977-10-08

Portal hypertension occurs in approximately 10% of patients with myelofibrosis. Increased portal blood flow secondary to splenomegaly has been proposed to explain its development. In a 60-year-old woman with proven myelofibrosis of 10 years' duration and gross splenomegaly, portal hypertension developed with ...

PubMed Central

53
Detection of liposomes in portal blood following oral administration
1984-10-01

125Iodine-labeled human immunoglobulin G-encapsulated dipalmitoyl phosphatidylcholine liposomes were prepared with or without asialoganglioside. Distribution of radioactivity following the oral administration of these liposomes in rats was checked in liver and in blood of the portal vein and heart. Gel filtration of plasma from the ...

Energy Citations Database

54
Determination of liver and spleen perfusion by quantitative sequential scintigraphy: results in normal subjects and in patients with portal hypertension
1981-05-01

Quantitative sequential hepatosplenic scintigraphy was performed to determine the arterial and portal components of the total liver circulation in 135 patients (no liver disease in 20, liver cirrhosis and portal ;hypertension in 115). Portal circulation in healthy patients is calculated to be 70.4 +/- 6.2% of the total liver ...

Energy Citations Database

55
[Value of hepatic angioscintigraphy combined to pulsed Echo-Doppler: application to the study of portal hypertension of cirrhotic patients. Apropos of 148 cases].
1991-01-01

Quantitative hepatic angioscintigraphy was combined with duplex Doppler in order to study liver perfusion in normal subjects and in 148 patients with liver cirrhosis. The portal component of liver perfusion determined by scintigraphy was reduced in patients with liver cirrhosis and correlated to the development of cirrhosis and to porto-hepatic gradient pressure. Duplex ...

PubMed

56
Evolution of portal hypertension and mechanisms involved in its maintenance in a rat model
1985-06-01

In rats with portal hypertension induced by partial ligation of the portal vein, the authors have recently demonstrated an increased portal venous inflow that becomes an important factor in the maintenance of portal hypertension. The sequence of events that leads into this circulatory disarray is unknown. The ...

Energy Citations Database

57
Obstructive Sleep Apnea Linked to Blood Vessel Abnormalities

Obstructive sleep apnea linked to blood vessel abnormalities American Heart Association Rapid Access Journal Report Study Highlights : Sleep apnea can cause changes in blood vessel function that reduces blood supply to ...

MedlinePLUS

58
Portal hypertensive enteropathy diagnosed by capsule endoscopy and demonstration of the ileal changes after transjugular intrahepatic portosystemic shunt placement: a case report
2011-03-04

IntroductionRecent data suggest that mucosal abnormalities can occur even in the duodenum, jejunum, and distal ileum of cirrhosis patients. We present a case of portal hypertensive enteropathy in a cirrhosis patient shown by capsule endoscopy and the effect of transjugular intrahepatic portosystemic shunt on the ileal pictures.Case presentationAn ...

PubMed Central

59
Portal cavernoma: dynamic CT features and transient differences in hepatic attenuation
1985-03-01

Sixteen portal cavernomas were examined with dynamic computed tomography (CT) and confirmed by sonography. Characteristic features included loss of the normal vascular structure and the presence of sinuous collateral pathways which were enhanced during the portal phase. Fifteen patients exhibited transient differences in hepatic attenuation and peripheral ...

Energy Citations Database

60
The Hemostatic Derangement Produced by T-2 Toxin in ...

... Descriptors : *TOXICITY, *TOXINS AND ANTITOXINS, *GUINEA PIGS, *BLOOD COAGULATION, REPRINTS, ABNORMALITIES, BLOOD ...

DTIC Science & Technology

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61
Portal ductopathy: clinical importance and nomenclature.
2011-03-21

Non-cirrhotic portal hypertension (PHT) accounts for about 20% of all PHT cases, portal vein thrombosis (PVT) resulting in cavernous transformation being the most common cause. All known complications of PHT may be encountered in patients with chronic PVT. However, the effect of this entity on the biliary tree and pancreatic duct has not yet been fully ...

PubMed

62
Portal ductopathy: Clinical importance and nomenclature
2011-03-21

Non-cirrhotic portal hypertension (PHT) accounts for about 20% of all PHT cases, portal vein thrombosis (PVT) resulting in cavernous transformation being the most common cause. All known complications of PHT may be encountered in patients with chronic PVT. However, the effect of this entity on the biliary tree and pancreatic duct has not yet been fully ...

PubMed Central

63
Pseudosclerosing cholangitis in extrahepatic portal venous obstruction.
1992-02-01

Biliary changes secondary to portal hypertension have rarely been described in published reports. Twenty consecutive patients with extrahepatic portal venous obstruction, all of whom showed a variable degree of abnormalities in the biliary tract suggestive of sclerosing cholangitis, are described. These biliary ...

PubMed Central

64
Cavo-portal transposition in rat: a new simple model
2007-08-16

BackgroundLiver transplantation in presence of diffuse portal vein thrombosis is possible by using caval blood as portal inflow, through cavo-portal transposition. However, clinical results are heterogeneous and experimental studies are needed, but similar hemodynamic conditions are difficult to obtain, especially ...

PubMed Central

65
Lymphatic marker podoplanin/D2-40 in human advanced cirrhotic liver- Re-evaluations of microlymphatic abnormalities
2010-11-08

BackgroundFrom the morphological appearance, it was impossible to distinguish terminal portal venules from small lymphatic vessels in the portal tract even using histochemical microscopic techniques. Recently, D2-40 was found to be expressed at a high level in lymphatic endothelial cells (LECs). This study was undertaken to elucidate hepatic lymphatic ...

PubMed Central

66
Portal biliopathy: a multitechnique imaging approach.
2011-06-17

Portal biliopathy (PB) is a disorder characterized by biliary ductal and gallbladder wall abnormalities seen in patients with extrahepatic portal vein obstruction. These abnormalities consist mainly of bile duct compression and tethering, stenoses, fibrotic strictures and dilatation of both extrahepatic and ...

PubMed

67
46 CFR 197.560 - Medical surveillance.
2010-10-01

...blood dyscrasias including genetic hemoglobin abnormalities...of the following abnormal conditions exist, the blood count must... (2) If the abnormal conditions persist, the employee must...this subpart for examples of conditions in which referrals may...

Code of Federal Regulations, 2010

68
The Effects of Cardiopulmonary Bypass on Hemostasis.
1993-05-12

... ABNORMALITIES, CAPILLARITY, ORGANS(ANATOMY), BLOOD PLATELETS, CARDIOLOGY, ANTICOAGULANTS, INTRAVASCULAR CLOTS ...

DTIC Science & Technology

69
JAMA Patient Page: Childhood Leukemia

... girls. Leukemia is believed to be caused by genetic mutations �abnormal changes in the genes of blood cells. ...

MedlinePLUS

70
Intracerebral hemorrhage (image)

... or abnormalities of the blood vessels (aneurysm or angioma). When it is not caused by one of ...

MedlinePLUS

71
Disseminated Intravascular Coagulation in 'Macaca mulatta' ...
1977-06-10

... The prolongation of the APTT was indicative of an abnormality in the intrinsic blood coagulation system, and was interpreted as indirect evidence of ...

DTIC Science & Technology

72
Intrahepatic portal vein sclerosis in patients without a history of liver disease. An autopsy study.
1982-01-01

Portal fibrosis with portal venous obliteration is characteristic of noncirrhotic portal hypertension, but similar lesions are also commonly seen in patients without clinical evidence of liver disease. Thus, the ability to predict the presence of portal hypertension with histologic criteria will probably depend on ...

PubMed Central

73
Myelofibrosis and angiodysplasia of the colon: another manifestation of portal hypertension and massive splenomegaly?
2004-09-01

Bleeding owing to portal hypertensive colopathy, a form of large bowel angiodysplasia, as a cause of increased blood transfusion requirement is described in a 74 year old man with idiopathic myelofibrosis. The proposed mechanism and the potential therapeutic options for this rare complication of myelofibrosis are discussed.

PubMed Central

74
[Progress in portal hypertension].
2009-06-21

In patients with portal hypertension due to cirrhosis, the mechanisms responsible for circulatory modifications are well-known. An elevation in intrahepatic vascular resistance related to a hepatic endothelin hyperproduction and an arterial nitric oxide (NO) hyperproduction. The presence and the degree of portal hypertension might be determined by the ...

PubMed

75
Ethanol-induced increase in portal blood flow: Role of acetate and A sub 1 - and A sub 2 -adenosine receptors
1988-10-01

The increase in portal blood flow induced by ethanol appears to be adenosine mediated. Acetate, which is released by the liver during ethanol metabolism, is known to increase adenosine levels in tissues and in blood. The effects of acetate on portal blood flow were investigated in rats using ...

Energy Citations Database

76
Use of the Umbilical Vein to Study the Splanchnic and Portal Beds in Shock and Trauma: II. Metabolic Studies
1974-07-01

Perumbilical portal vein catheters and arterial and central venous catheters were inserted in 16 patients recovering from trauma or other shock-producing events, and in 5 patients who later developed shock. This permitted serial measurement of blood gases, pH, and the levels of ammonia, lactate and certain other metabolites in all three circulatory systems ...

PubMed Central

77
Use of capillary electrophoresis and fluorescent labeled peptides to detect the abnormal prion protein in the blood of ...

... it possible to detect the abnormal protein in blood. A peptide from the carboxyl terminal region, amino ... labeled peptide in the capillary was 50 amol. Blood was obtained from normal sheep and elk, from...

NBII National Biological Information Infrastructure

78
Use of Capillary Electrophoresis and Fluorescent Labeled Peptides to Detect the Abnormal Prion Protein in the Blood of ...

... it possible to detect the abnormal protein in blood. A peptide from the carboxyl terminal region, amino ... labeled peptide in the capillary was 50 amol. Blood was obtained from normal sheep and elk, from...

NBII National Biological Information Infrastructure

79
Secretion of dopamine and norepinephrine in hypophyseal portal blood and prolactin in peripheral blood of Holstein cattle.
2001-02-01

The objective was to test the hypothesis that dopamine regulates prolactin (PRL) secretion by determining acute changes in catecholamine concentrations in hypophyseal portal blood of cattle, and their relation to peripheral blood concentration of PRL in hypophyseal stalk-transected (HST) and sham-operated controls (SOC). Holstein ...

PubMed

80
Route of Absorption of DDVP after Oral Administration to Rats.
1965-01-01

Ten rats were infused by stomach tube with radioactive DDVP while timed samples of portal blood, systemic venous blood, and chyle were taken. Levels of DDVP were determined in all samples and were found to be much higher in portal blood than in either sys...

National Technical Information Service (NTIS)

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81
Insight into congenital absence of the portal vein: Is it rare?
2008-10-21

Congenital absence of portal vein (CAPV) was a rare event in the past. However, the number of detected CAPV cases has increased in recent years because of advances in imaging techniques. Patients with CAPV present with portal hypertension (PH) or porto-systemic encephalopathy (PSE), but these conditions rarely occur until the patients grow up or become ...

PubMed Central

82
Specimens - EDRN Public Portal
2011-08-05

of Michigan from 986 participants diagnosed without cancer. Read More... 11547 Blood/Plasma Specimens at UMICH from 974 without Cancer Collected at University of Michigan from...

Science.gov Websites

83
STUDIES ON THE ETIOLOGY OF EXPERIMENTAL SHOCK
1961-05-05

... activity of portal blood and the serotonin content of intestinal tissues of ... infection reflect a shift from normal pathways--iron absorption, storage, and ...

DTIC Science & Technology

84
PATHOGENESIS OF LETHAL SHOCK AFTER ...
2011-05-14

... venous pressure, portal pressure, perimental animals, has been reported to produce cardiac output, carotid artery flow, and blood shock and an ...

DTIC Science & Technology

85
Measurements of the extent of hypertension (aortae ... - GCMD - NASA

The extent of hypertension was assessed by measuring dorsal and ventral aortae blood pressures, ... USA dot gov - The U.S. Government's Official Web Portal ...

NASA Website

86
Investigation of Intermediary Metabolism and Energy ...
1976-10-07

... Abstract : Insulin to glucagon (I/G) ratios were found to be higher in portal than in peripheral blood in human subjects in the postabsorptive state ...

DTIC Science & Technology

87
Sickle Cell Anemia
2010-06-23

Sickle cell anemia is a genetically inherited disease in which red blood cells form an abnormal crescent shape. This animation illustrates the cause and effects of the abnormal cell shape.

NSDL National Science Digital Library

88
Renal scan: MedlinePlus Medical Encyclopedia
2011-08-03

to look for signs of transplant rejection. It may also be done on those with high blood pressure to check differential kidney function. What Abnormal Results Mean Abnormal...

Science.gov Websites

89
Double aortic arch

... aortic arch is an abnormal formation of the aorta, the large artery that carries blood from the ... defects that affect the development of the baby�s aorta in the womb. These defects cause an abnormal ...

MedlinePLUS

90
Noncirrhotic portal vein thrombosis. Physiology before and after shunts.
1980-09-01

Controversy exists concerning the proper therapy for bleeding gastroesophageal varices secondary to noncirrhotic portal vein thrombosis. Disparity of opinion exists regarding the significance of hepatic portal blood flow and the consequences of total portal-systemic shunts in this condition. One patient is ...

PubMed Central

91
Successful Treatment for Hepatic Encephalopathy Aggravated by Portal Vein Thrombosis with Balloon-Occluded Retrograde Transvenous Obliteration
2011-07-08

This report presents the case of a 78-year-old female with hepatic encephalopathy due to an inferior mesenteric venous-inferior vena cava shunt. She developed hepatocellular carcinoma affected by hepatitis C virus-related cirrhosis and underwent posterior sectionectomy. Portal vein thrombosis developed and the portal trunk was narrowed after hepatectomy. ...

PubMed Central

92
Diagnosis of an Accessory Portal Vein and Its Clinical Implications for Portosystemic Shunts
1996-04-15

Purpose: To present a peculiar anatomic portal veins variant and evaluate its clinical implications. Methods: Among 118 consecutive patients undergoing transjugular intrahepatic portosystemic shunting (TIPS), six male patients were found to have an accessory portal vein, which was seen during direct portography. Results: In all six patients, portograms ...

Energy Citations Database

93
Researchers Find Abnormal Cells in the Blood Years before Leukemia is Diagnosed

Researchers Find Abnormal Cells in the Blood Years before Leukemia is Diagnosed Researchers have shown that abnormal white blood cells can be present in patients' blood more than six years prior to the diagnosis of a chronic form of lymphocytic leukemia. This finding may lead to a better ...

Cancer.gov

94
Non-Newtonian Blood Flow in Portal Vein with Thrombosis: A Study by Computational Fluid Dynamics
2011-09-01

We investigate the effects on non-Newtonian blood flow model on the wall shear stress (wss), velocity and viscosity distributions. The 3D Navier-Stokes equations coupled with viscosity models describing the steady flow in Portal Vein have been solved numerically. Three blood viscosity models (Newtonian, Power-law and Carreau) are used ...

NASA Astrophysics Data System (ADS)

95
Using Transjugular Intrahepatic Portosystemic Shunts for Complications of Cirrhosis.
2011-06-21

Cirrhosis is a leading cause of morbidity and mortality and often arises during the development of portal hypertension and its related complications. Portal decompression is therefore an important therapeutic objective. Historically, portal decompression was achieved by surgical diversion of blood from the ...

PubMed

96
Observations on the rare association between portal and pulmonary hypertension.
1980-12-01

Pulmonary arterial hypertension with severe pulmonary vascular disease is a rare association of portal hypertension in man, be it the result of cirrhosis of the liver or obstruction of the portal vein. We induced portal hypertension in 23 rats by partially ligating the portal vein or by totally occluding it in two ...

PubMed Central

97
Endothelial dysfunction in the regulation of cirrhosis and portal hypertension.
2011-07-01

Portal hypertension is caused by an increased intrahepatic resistance, a major consequence of cirrhosis. Endothelial dysfunction in liver sinusoidal endothelial cells (LSECs) decreases the production of vasodilators, such as nitric oxide, and favours vasoconstriction. This contributes to an increased vascular resistance in the intrahepatic/sinusoidal microcirculation and ...

PubMed

98
Hemodynamics of portal blood flow shown by CT portography: work in progress
1985-02-01

Computed tomography and arterial portography were combined in 12 patients for studies of the anatomy and hemodynamics of the portal venous system. This technique was found to be more sensitive than conventional venous-phase angiograms of the superior mesenteric and splenic arteries for evaluation of the anatomy of the portal venous system and extent of ...

Energy Citations Database

99
Pregnancy Complications: Umbilical Cord Abnormalities

... Click on the stars below. 4 Umbilical cord abnormalities The umbilical cord is a narrow tube-like ... and protects these blood vessels. A number of abnormalities can affect the umbilical cord. The cord may ...

MedlinePLUS

100
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
2009-05-06

Ascites; Blunt Abdominal Trauma; Cholelithiasis; Cholecystitis; Cholangitis; Pancreatitis; Hydronephrosis; Abdominal Aortic Aneurysm; Hepatitis; Portal Hypertension; Urolithiasis; Abnormal Uterine Bleeding; Ovarian Mass; Ovarian Torsion

ClinicalTrials.gov

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101
Study for Recycling of Norm Contaminated Steel Scraps from Steel Industry.
2003-01-01

Since 1994, most of the major steel industries in Taiwan have installed portal monitor to detect the abnormal radiation in metal scrap feed. As a result, the discovery of NORM (Naturally Occurring Radioactive Material) has increased in recent years. In or...

National Technical Information Service (NTIS)

102
Radiological Findings in a Case of Multiple Focal Nodular Hyperplasia Associated with Portal Vein Atresia and Portopulmonary Hypertension
2008-08-20

We present here the radiological findings of a rare case of multiple focal nodular hyperplasia that was associated with portal vein atresia and portopulmonary hypertension in a young woman. This case illustrates and supports the pathophysiological hypotheses that were previously proposed for the coexistence of these three abnormalities.

PubMed Central

103
Liver transplantation in patients with patent splenorenal shunts
1987-04-01

Patent distal splenorenal shunts (Warren shunt) have been reported to cause decreases in the portal perfusion pressure and the total hepatic blood flow. Such hemodynamic alterations could have adverse effects on the transplanted liver. The experience with hepatic replacement in four patients with patent Warren shunts is reported. Operative findings were ...

PubMed Central

104
Reversal of abnormal fibrinolytic activity, blood coagulation factors and platelet function in high-altitude pulmonary oedema with frusemide
1973-03-01

Reversal of abnormal fibrinolytic activity, blood coagulation factors and platelet function in high-altitude pulmonary oedema with frusemide

NASA Astrophysics Data System (ADS)

105
Eur J Nucl Med Mol Imaging. Author manuscript Page /1 14

Eur J Nucl Med Mol Imaging. Author manuscript Page /1 14 Non-invasive estimation of hepatic blood Slimani Abstract The liver is perfused through the portal vein and the hepatic generally obtained invasively, but blood withdrawal from the portal vein is not feasible in humans. The aim

E-print Network

106
Contrast-enhanced portal magnetic resonance angiography in dogs with suspected congenital portal vascular anomalies.
2010-12-13

Contrast-enhanced multiphase magnetic resonance angiography (CE-MRA) was used in 17 dogs with a suspected congenital portal vascular anomaly. Portal vascular anomalies were identified in 16 of the 17 dogs. Eleven had a single intrahepatic portocaval shunt (two central divisional, three right divisional, and six left divisional), one dog had a double ...

PubMed

107
42 CFR 493.941 - Hematology (including routine hematology and coagulation).
2010-10-01

...Test Procedure Cell identification or white blood cell differential Erythrocyte count Hematocrit...Lymphocytes Monocytes Major red and white blood cell abnormalities Immature red and white blood cells (2) White blood cell...

Code of Federal Regulations, 2010

108
Red blood cells, tear-drop shape (image)

... photomicrograph shows one of the abnormal shapes that red blood cells (RBCs) may assume, a tear-drop ...

MedlinePLUS

109
Red blood cells, target cells (image)

These abnormal red blood cells (RBCs) resemble targets. These cells are seen in association with some forms of anemia, and following the removal of the ...

MedlinePLUS

110
Presbycusis

... blood supply to the ear because of heart disease, high blood pressure, ... ear and/or middle ear. Such abnormalities may include reduced function of ...

MedlinePLUS

111
Obstructive Sleep Apnea Linked to Blood Vessel Abnormalities

... blood vessels, Lip said. Furthermore, patients in the control groups weren�t treated with CPAP therapy, which would ...

MedlinePLUS

112
Imatinib

... is used to treat certain types of leukemia (cancer that begins in the white blood cells) and other cancers of the blood cells. Imatinib is also used ... the action of the abnormal protein that signals cancer cells to multiply. This helps stop the spread ...

MedlinePLUS

113
How Is Colorectal Cancer Diagnosed?

... a lubricated, gloved finger into the rectum to feel for any abnormal areas. Blood tests Your doctor may also order certain blood ...

MedlinePLUS

114
Could astronauts return to earth after travelling to

Aug 24, 2011... abnormal taste and smell, nausea, vomiting, diarrhea, decreased blood pressure, decreased white blood cells, irritability, and insomnia. ...

NASA Website

115
Common Eye Disorders

... stage). Diabetic retinopathy usually affects both eyes. The risks of DR are reduced through disease management that includes good control of blood sugar, blood pressure, and lipid abnormalities. ...

MedlinePLUS

116
Adult Acute Myeloid Leukemia Treatment (PDQ®)

Adult acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes abnormal myeloblasts (a type of white blood cell), red blood cells, or platelets.

Cancer.gov

117
Tourette Syndrome: Frequently Asked Questions

... be abnormal activity of the receptor for this chemical as well. Undoubtedly, ... their onset. No blood analysis or other type of neurological testing exists to ...

MedlinePLUS

118
Thalassemia major (image)

... an inherited form of hemolytic anemia, characterized by red blood cell (hemoglobin) production abnormalities. This is the most severe form of ...

MedlinePLUS

119
Neuroendocrine Abnormalities in Patients with Traumatic ...
2011-05-14

... and glncocorticoid agonists and antagonists on blood ... response between growth hormone-releasing factor and ... and thyroid hormones in traumatic ...

DTIC Science & Technology

120
Fructosamine: Structure, Analysis, and Clinical Usefulness,

... The amount of fructosamine in serum is increased in diabetes mellitus owing to the abnormally high concentration of sugar in blood. ...

DTIC Science & Technology

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121
Disseminated Intravascular Coagulation in 'Macaca mulatta' ...
1977-06-10

... ntred) " abnormality in the intrinsic blood coagulation system, and was interpreted as indirect evidence of Hageman factor activation,, which was the ...

DTIC Science & Technology

122
Budd-Chiari Syndrome

... when there is no obvious cause, even after testing Abnormal results ... magnetic resonance imaging of blood vessels (magnetic resonance angiography) ...

MedlinePLUS

123
Birthmarks

Birthmarks are abnormalities of the skin that are present when a baby is born. There are two types of birthmarks. Vascular birthmarks are made up of blood vessels ...

MedlinePLUS

124
A 90-Day Vapor Inhalation Toxicity Study of Decalin,

... There was no associated abnormal increase in mortality nor alterations in serum, blood urea nitrogen, or creatinine levels. ...

DTIC Science & Technology

125
Hemorrhage from varices in hepaticojejunostomy in the fifth and tenth year after surgery for hepatic hilar bile duct cancer: a case report
2008-07-25

We report a case of a 64-year-old female patient who underwent a right lobectomy of the liver (including total resection of the caudate lobe), dissection of the group 2 lymph nodes, left hepaticojejunostomy (Roux-en-Y fashion), and reconstruction of the portal vein (end-to-end anastomosis between the main portal vein and the left ...

PubMed Central

126
[Abnormalities in renal hemodynamics].
2008-09-01

Chronic kidney disease (CKD) is a major risk factor for the development of cardiovascular disease (CVD). Abnormalities of renal hemodynamics are associated with CKD. Abnormalities in renal hemodynamics include blood flow into glomeruli, and tubulointerstitial tissue. Renin-angiotensin system, oxidative stress and NOS system affect ...

PubMed

127
If I Had - Abnormal Cholesterol on Routine Blood Work

... If I Had - Abnormal Cholesterol on Routine Blood Work - Dr. Lori Mosca, MD, MPh, PhD, NewYork Presbyterian ... If I Had - Abnormal Cholesterol on Routine Blood Work - Dr. Lori Mosca, MD, MPh, PhD, NewYork Presbyterian ...

MedlinePLUS

128
[Portal venous flow (ultrasonography-Doppler) in patients with alcoholic liver cirrhosis].
1991-05-01

To evaluate the clinical usefulness of the ultrasonographic (echo-Doppler) measurements of portal blood flow their results were compared with several clinical and biochemical parameters in alcoholic cirrhotic patients. The technique was standardized and its reproducibility was checked in 30 cirrhotics and in 20 control subjects. In controls, ...

PubMed

129
Noninvasive measurement of nutrient portal blood shunting: an experimental study with (/sup 14/C)ursodeoxycholic acid

All of the methods proposed for measuring portal blood flow are either invasive, estimate total rather than nutrient flow, and none has proved reliable in cirrhotic patients. A method has been derived from pharmacokinetic principles used for the calculation of bioavailability of drugs according to the route of administration (i.v. or p.o.) and tested ...

Energy Citations Database

130
Daily variation in portal blood flow and the effect of propranolol administration in a randomized study of patients with cirrhosis.
1997-03-01

A nocturnal increase in portal pressure and blood flow was demonstrated in patients with cirrhosis, suggesting that these hemodynamic changes may contribute to the triggering of the hemorrhagic episodes observed during the night in these patients. It is known that propranolol reduces portal flow, thus reducing the risk of variceal ...

PubMed

131
The Fontan procedure: anatomy, complications, and manifestations of failure.

The Fontan procedure refers to any operation that results in the flow of systemic venous blood to the lungs without passing through a ventricle. It is performed to treat several complex congenital heart abnormalities including tricuspid atresia, pulmonary atresia with intact ventricular septum, hypoplastic left heart syndrome, and double-inlet ventricle. ...

PubMed

132
Suppression of cellular immunity by head and neck irradiation. Precipitating factors and reparative mechanisms in an experimental model
1986-11-01

A model was developed in C/sub 3/H mice to investigate the immunosuppressive effects of head and neck irradiation and to explore mechanisms for repair of the defects. Mice receiving 1200 rad (12 Gy) of head and neck irradiation showed significant depression of delayed-type hypersensitivity, peripheral blood lymphocyte counts, spleen cell counts, and spleen cell production of ...

Energy Citations Database

133
Hemodynamic evaluation of the right portal vein in healthy dogs of different body weights
2010-05-25

BackgroundDoppler ultrasonography is an important tool for evaluating hepatic portal hemodynamics. However, no study in dogs of different body weights, in the range encountered in routine clinical veterinary practice, has been reported. It can be difficult to obtain an ideal insonation angle when evaluating the main portal vein, so evaluation of the right ...

PubMed Central

134
Portal venous arterialization resulting in increased portal inflow and portal vein wall thickness in rats
2008-11-21

AIM: To explore the influence of portal vein hemo-dynamic changes after portal venous arterialization (PVA) on peribiliary vascular plexus (PVP) morphological structure and hepatic pathology, and to establish a theoretical basis for the clinical application of PVA.METHODS: Sprague-Dawley rats were randomly divided into control and PVA groups. After PVA, ...

PubMed Central

135
Transjugular Intrahepatic Portosystemic Shunt in a Patient with Cavernomatous Portal Vein Occlusion
2000-03-15

A 23-year-old woman with liver cirrhosis secondary to primary sclerosing cholangitis was referred to us for the treatment of recurrent bleeding from esophageal varices that had been refractory to endoscopic sclerotherapy. Her portal vein was occluded, associated with cavernous transformation. A transjugular intrahepatic portosystemic shunt (TIPS) was performed after a ...

Energy Citations Database

136
An improved method of estimating the portal venous fraction of total hepatic blood flow from computerized radionuclide angiography
1983-05-01

The measurement of portal venous flow to the liver is important in the evaluation of patients for shunt surgery. A previous report described a method using slope analysis of hepatic radionuclide angiograms to generate an index of relative portal flow, which correlated well with angiographic grades of portal perfusion. The present ...

Energy Citations Database

137
An improved method of estimating the portal venous fraction of total hepatic blood flow from computerized radionuclide angiography
1983-05-01

The measurement of portal venous flow to the liver is important in the evaluation of patients for shunt surgery. A previous report described a method using slope analysis of hepatic radionuclide angiograms to generate an index of relative portal flow, which correlated well with angiographic grades of portal perfusion. The present ...

Energy Citations Database

138
Portal biliopathy treated with living-donor liver transplant: index case.
2011-04-01

Portal biliopathy refers to abnormalities of the entire biliary tract in patients with extrahepatic portal vein obstruction. Most of the patients are asymptomatic. However, more than 80% of patients show characteristic morphologic features on endoscopic retrograde cholangiopancreatography. Symptomatic cases usually require therapy. The ...

PubMed

139
Congenital extrahepatic portocaval shunt (Abernethy type 2), huge liver mass, and patent ductus arteriosus--a case report of its rare clinical presentation in a young girl.
2003-04-01

The authors report a case of congenital extrahepatic portocaval shunt with a hypoplastic portal vein. This type of shunt is called an Abernethy type 2 shunt, where the portal vein and inferior vena cava are connected side to side, and a hypoplastic portal flow exists in the liver parenchyma. This case of a young girl is complicated ...

PubMed

140
[The measurement of hepatic circulation before and after orthotopic liver transplantation in dog--by using transit-time blood flow meter and H2 clearance method].
1989-02-01

Orthotopic liver transplantation was successfully carried out in 40 mongrel dogs, in which hepatic circulation was investigated before and after grafting. Blood flows in hepatic artery, portal vein and intrahepatic inferior vena cava were measured by using transit-time ultrasonic blood flow meter and regional tissue ...

PubMed

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141
A new non-invasive method of evaluating portal-systemic shunting by computer quantitation of hepatic and pulmonary activity after rectal delivery of Xe-133
1984-01-01

While portal blood flow and portal-systemic shunting have been previously studied with Xe-133, lack of computer quantitation and invasive isotope delivery into the portal circulation have severely limited the procedure's value. However, the authors method of rectal delivery of Xe-133 solubilized in water ...

Energy Citations Database

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