... congenital acetabular retroversion, developmental dysplasia of ... as well as any abnormality resulting in ... 5) The chondral abnormalities resulting from ...
DTIC Science & Technology
... Screening of 1100 mutagenised mice and the identification of a number of developmental abnormalities including tumorigenesis, providing a ...
... extra legs, cecum, cloaca, scoliosis, skeletal abnormalities, malformation, developmental abnormalities Developmental abnormalities have been described in domestic fowl ... ...
NBII National Biological Information Infrastructure
Recent advancements in molecular developmental biology afford an opportunity to apply newly developed tools for understanding the mechanisms of both normal and abnormal development. lthough a number of agents have been identified as causing developmental abnormalities, knowledge ...
EPA Science Inventory
... 0067 Variation in Premaxillary Tooth Count and a Developmental Abnormality in a Tyrannosaurid DinosaurTetsuto Miyashita, Darren ...
... moderate disabilities linked with this condition. Growth and developmental abnormalities. Are there any indications of problems with mental ... acne can also be an indication of a developmental abnormality. Drug-induced acne or acneiform eruption. Has the ...
MedlinePLUS
Apr 21, 2011 ... Developmental abnormalities were studied in newborns obtained on the 22nd/23rd gestational day. We were provided with a newborn pup from the ...
NASA Website
... Environmental exposure to antiandrogens, such as DDT, can cause developmental abnormalities. 2 On the other hand, ...
... These topics include: Epidemiology; Mutagenesis, Carcinogenesis, and Cytogenetic Effects; Teratogenesis and Developmental Abnormalities ...
The paper reviews some of the important issues that may lead to understanding basic developmental processes and mechanisms by which toxic agents may interfere with normal and abnormal development. Approximately 70% of developmental defects are of unknown ...
National Technical Information Service (NTIS)
... contaminated site. In surviving larvae, the frequency of developmental abnormalities and abnormal swimming was 55-58% higher in ... ...
... H. F. Percival, and A. R. Woodward. 1994. Developmental abnormalities of the gonad and abnormal sex hormone concentrations ... ...
... developmental deficits No evidence for damage to or loss of neurons or ... Special Safety Categories�MRI Abnormalities 2006: Increased T2 MRI signal abnormality ...
Center for Biologics Evaluation and Research (CBER)
Joubert syndrome is characterized by episodes of abnormal respiratory pattern, oculomotor findings, hypotonia, ataxia, developmental retardation with evidence of neuropathologic abnormalities of cerebellum
E-print Network
1425 ... www.nlm.nih.gov ... As a fetus develops, the formation of the internal and/or external sexual organs may be abnormal. This abnormal ...
... Received: November 21, 2002Keywords: tawny owl, Strix aluco, developmental abnormalities, skeletal deformities, congenital malformations CASE REPORT Avian congenital ... ...
... equal 1 cm. TABLE 1. Occurrence of major developmental abnormalities in dipnoan taxa. Asterisk indicates presence, dash indicates ... ...
... 95 molted adult ticks (64.2%) displayed marked developmental abnormalities and had fewer than eight legs (three to seven legs per tick). Developmental abnormalities were not seen in the first rabbit infest...
Developmental abnormalities are described in a peregrine falcon (Falco peregrinus) and a merlin (Falco columbarius). The former had duplication of a hind toe and extra vestigial digits on a carpus, while the latter showed syndactyly. PMID:18766875
PubMed
... 2001 doi: 10.1095/biolreprod65.1.204 Chromosomal Abnormalities and Developmental Kinetics in In Vivo-Develo...
... was very slight (Table 5). In addition, no developmental abnormalities were found in progeny. Feeding Deterrence Linear regression ... killed by C. longa leaf oil, since no developmental abnormalities ...
... These developmental effects include: death of the developing organism, structural abnormalities, altered growth, and functional deficiencies. ...
EPA Pesticide Factsheets
... Of considerable interest, these chimeras exhibit numerous developmental and histological abnormalities, indicative of a requirement for merlin ...
... 2) The developmental stage of the embryos ... Descriptors : *ABNORMALITIES, *ELECTROMAGNETIC FIELDS, *EMBRYOS, *DEATH, INCUBATION ...
hide Your Search Criteria. Search All: (Abnormalities Developmental) � Remove All. Records; Concept Cloud. Matching Records: 886 ...
... mammary adenocarcinomas in a stochastic fashion, develop Harderian gland hyperplasia and have subtle developmental abnormalities of the ...
Apr 21, 2011 ... Chromosome breakage. Chromosome damage. Development Developmental abnormalities. ++ -- View more. Embryogenesis Mitotic forms ...
Jun 16, 2011 ... Developmental abnormalities in young fish indicate that selenium-induced teratogenesis and reproductive impairment are occurring. ...
Treesearch
Dec 8, 2006 ... flight demonstration of an AFSS developmental test article using .... any abnormalities that might spell trouble. As the tanking nears ...
... were unable to reach the swim-up stage Developmental abnormalities observed in 3-day old fry included alterations ... ...
Ethanol (EtOH) is a well-known developmental toxicant that produces a range of abnormal phenotypes. While the toxic potential of developmental EtOH exposure is well characterized, the effect of the timing of exposure on the extent of toxicity remains unknown. Fish models such as ...
... essential early developmental events and also contribute to developmental abnormalities and later failure. Genetically determined differences in how the oocyte cytoplasm modifies the incoming genome might ...
...2 ) All physical abnormalities (e.g., stunted...effects �(1) Developmental toxicity testing...Required testing. Developmental toxicity testing...requirements. (A) The developmental toxicity test...
Code of Federal Regulations, 2010
The aetiology of profound hearing loss in children is complex and multifactorial. Congenital inner ear abnormality is a major cause of hearing loss in children. CT temporal bone imaging is the modality of choice in the investigation of hearing loss. Recognising the congenital abnormalities of the inner ear guides the clinician's management of the ...
This Environmental Health Perspectives journal article documents a study on the relationship between brevetoxin, a toxin produced by red tide-related dinoflagellates, and abnormalities in fish embryos. The article features color photographs, charts, and tables.
NSDL National Science Digital Library
... 2000; Johnson et al., 2002). Trauma related and developmental abnormalities are typically found in amphibian populations at frequencies ... A. and S. T. Threlkeld. 1998. Abundance, metamorphosis, developm...
... Ninety percent of exposed tadpoles displayed oral disc abnormalities, while no control individuals displayed abnormalities. Tadpoles raised on CCR-contaminated sediment had decreased ... ...
There are a wide variety of congenital midface abnormalities that originate during transformation of the first pair of pharyngeal arches into adult structures. Computed tomography and magnetic resonance imaging are important components in the comprehensive evaluation of these lesions. A detailed understanding of midface embryogenesis and developmental ...
The incidence of developmental abnormalities in domestic animals is low, however there is continuing pressure on the veterinarian to answer concerns of the producer as to why the abnormality occurred and what significance it has for the rest of the herd. Generally, both normal and abnormal development are products ...
PubMed Central
Possible Complications Babies born with tracheomalacia may have other congenital abnormalities such as heart defects, developmental delay, or gastroesophageal reflux....
Science.gov Websites
... F., B. M. Pezzanite, and P. Matulonis. 2003. Developmental abnormalities in wild populations of birds: examples from lesser ... ...
Nov 1, 2005 ... Embryos were examined for developmental abnormalities, subsamples removed for RNA and protein extraction and the remaining samples preserved ...
Embryos were examined for developmental abnormalities, subsamples removed for RNA and protein extraction and the remaining samples preserved for later DNA ...
... cell division described above (Frankel 1964). Such a developmental abnormality was not observed during transient inhibition of cell ... ...
... c) Predictive biomarkers in toddlers (age 18-30 months) with developmental delay who fail a standardized autism screening test (MCHAT) and are ...
... The fetuses are observed, preserved, and examined for skeletal and soft-tissue abnormalities ... The adverse effects are as end points that may be used to evaluate ...
Center for Food Safety and Applied Nutrition (CFSAN)
Selected Navigations: Publication Year > 1991-2000 [x]; Search Criteria: Search Field: All > Results : All > Search Term: (Abnormalities Developmental) [x] ...
... and that a significant number of these contain developmental abnormalities. Specific effects on the development of sexual stages, ... ...
Apr 21, 2011 ... + Development of Sensory Receptors in Skeletal Muscle (9303006) + Developmental Abnormalities (PARE.04C) ...
Search Criteria: Search Field: All > Results : All > Search Term: (Abnormalities Developmental) [x]. Sort results by: NASA Center | Date Added to NTRS ...
NASA Center > Marshall Space Flight Center [x]; Search Criteria: Search Field: All > Results : All > Search Term: (Abnormalities Developmental) [x] ...
... to 125 µg/liter), no increased mortality or developmental abnormalities were detected. Although they also did not find any limb malformations at the highest methoprene concentration tested ... lethal deve...
Apr 21, 2011 ... + Development of Sensory Receptors in Skeletal Muscle (9303006) + Developmental Abnormalities (PARE.04C) + Effect of Microgravity on ...
... but were rather casualties of starvation caused by developmental abnormalities (C. van Oosterhout, pers. observ.). Were these individuals ... ...
... introduces some epigenetic defects that can lead to developmental abnormalities [4]. Germline epigenetic modifications characterized by the addition ... ...
... compulsive disorder (OCD), or a developmental disorder called autism that affects communication and social interaction. Abnormalities of the genitalia and ...
... M. Yasuda, R. G. York. 1997. Terminology of developmental abnormalities in common laboratory mammals (Version 1). Teratology 55: ... ...
... Medaka Embryo-Larval Bioassay for Rapid Determination of Developmental Abnormalities. Archives of Environmental Contamination and Toxicology 51:4, ... ...
... group with anasarca at external examination also had multiple visceral malformations which included partial cleft palate, abnormalities of the heart ...
... on the effect of culture stress on subsequent developmental abnormalities in the ruminant embryo. Acknowledgments The excellent technical ... ...
... mortality were identified early in the experiment by developmental abnormalities and unusually slow development, before the treatments had ... ...
... collected from three Maine offshore islands where chick developmental abnormalities had been previously reported, and from two nearby ... ...
... with the AI group. DISCUSSION A plethora of developmental abnormalities associated with cloning by NT have been reported ... ...
Science Discipline. Cell/Developmental Biology ... Electron micrographs showed no abnormalities and few differences between flight and control organisms. ...
... Kodak and; Chemical carcinogensis; DNA damage; Diethylnitrosamine; Benzo(a)pyrene; Detoxification; Developmental abnormalities; RA3. ...
removed for teardown inspection if no abnormalities are found. ...... developmental unit and assocJ ated ground- controlled television assembly and lunar ...
... difficult to directly determine the consequences of these developmental abnormalities relative to reproductive fitness; however, evidence suggests reduced ... ...
... of solenidia can vary as a result of developmental abnormalities, which are especially likely for species that overwinter ... ...
...bronchial asthma and urticaria, may not be disposed of routinely for compensation purposes as constitutional or developmental abnormalities. Service connection must be determined on the evidence as to existence prior to enlistment and,...
Jan 17, 2003 ... Similarly, a developmental vehicle like the Shuttle should be ...... Other abnormalities also occurred during re-entry. Early in ...
The Havanese is a toy breed that presents with a wide range of developmental abnormalities. Skeletal defects, particularly osteochondrodysplasia (OCD), are the most frequently observed anomalies. Cataracts, liver shunts, heart murmurs, and missing incisors are also common in this breed. Estimates of heritability and complex segregation analyses were ...
. (1992). There are no children here: The story of two boys growing up in the other America. New York of resilient teens. Cambridge, Massachusetts: Harvard University Press. ISBN: 0674027345 COURSE OBJECTIVES Utilize a biopsychosocial perspective to explore children's normal and abnormal developmental processes
... that allowed for successful completion of metamorphosis other developmental abnormalities have been reported in crustacean larvae (Table 2). Additional developmental intermediates or supernumerary larval s...
Alterations in the developmental processes of embryos resulting from exposure to chemicals are not limited to morphological abnormalities that can be observed in the near term fetus. In the research on the developmental toxicology of pesticides the author...
Alterations in the developmental processes of embryos resulting from exposure to chemicals are not limited to morphological abnormalities that can be observed in the near term fetus. In the research on the developmental toxicology of pesticides the authors have noted morphologica...
The authors describe a 3-month-old female infant with infantile rhegmatogenous retinal detachment with no associated congenital or developmental abnormalities. The unique presentation of this patient indicates that the detachment was a result of an early developmental defect. PMID:21751768
... in Drosophila. Heterozygous mutations increase the proportion of developmental abnormalities in the population into which they are introduced. ... rat (rSey): A new mutant rat with craniofacial abnormalit...
Adult exposure to the neurotoxicant 3,3'-iminodipropionitrile (IDPN) induces a hyperkinetic syndrome consisting of spontaneous head movements, abnormal circling, backwards locomotion, and sensory disruption. e report here the behavioral effects of developmental exposure to IDPN i...
...any manifestation of joint pain, any abnormality of heart action or heart sounds...disorders which are characterized by developmental defects or pathological trends in...showing preservice origin. Congenital or developmental defects, refractive error of the...
This study was performed to evaluate the cerebral protein synthesis rate of language brain regions in children with developmental delay with and without pervasive developmental disorder. The authors performed L-[1-(11)C]-leucine positron emission tomography (PET) on 8 developmental delay children with pervasive ...
Submicroscopic deletion of the terminal part of the short arm of chromosome 6, including 6p25, leads to developmental retardation, hearing impairment, ocular dysgenesis, and dysmorphic features. We diagnosed 3 patients referred because of white matter abnormalities of unknown origin. MR imaging showed multifocal areas of abnormal ...
Abstract During 1989-91, we assessed developmental abnormalities in embryos and hatchlings from eggs of the common snapping turtle ( Chelydra serpentina serpentina ). Eggs were collected and artificially incubated from eight sites in Ontario, Canada and Akwesasne/...
): theoretical (generative) vs. empirical (descriptive), abnormal (teratological) vs. normal, and juvenile vs, but there is much dissociation of growth trajectories in morphospace, with many instances of taxonomically are immediately relevant: theoretical/empirical, abnormal/normal, and juvenile/adult morphospaces (see also Eble
The authors studied the offspring of three generations of guinea pigs subjected to gamma-irradiation in doses of 225 and 450 r. Among the offspring of the first, second, and third generation the following developmental abnormalities were revealed: disturbance in the development of the skeleton, teeth, dwarfness, neoplasms, affection of the central ...
Energy Citations Database
Pregnant mice were irradiated with 150, 100, 50, or 25 r of x rays on the 8th day of gestation. The incidence of developmental abnormalities and the intensity and localization of malformations in the CNS usually paralleled the dosage. However, the type and degree of embryonic changes were quite different in each group. Embryos receiving more ...
Argues that knowledge from studies of individuals with sex chromosome abnormalities can further understanding of aspects of normal human development. Studies of XO girls, XXY boys, XXX girls, and males with a fragile X chromosome are summarized to demonstrate how results contribute to knowledge about normal cognitive development and about developmental ...
ERIC Educational Resources Information Center
Partial monosomy 10p is a rare chromosomal disorder characterised by frontal bossing, micrognathia, congenital heart defects, vesicoureteral abnormalities, and developmental delay. This is the first report to describe seizures not associated with hypocalcaemia, as well as cortical atrophy and decreased white matter volume on magnetic resonance imaging, in ...
This monograph addresses common misconceptions about developmental disabilities, describes the conditions that child welfare workers are most likely to see, provides examples of effective interventions, and stresses the importance of early intervention to promote healthy development. Specific chapters include: (1) "Understanding Developmental ...
It is critical for interventional electrophysiologists to thoroughly appreciate the topographic and developmental anatomy of the heart and its conduction system. Not only is understanding cardiac anatomy important to prevent complications from collateral damage and to help guide catheter placement, but developmental anatomy allows a deeper appreciation of ...
BackgroundWe used fMRI to examine functional brain abnormalities of German-speaking dyslexics who suffer from slow effortful reading but not from a reading accuracy problem. Similar to acquired cases of letter-by-letter reading, the developmental cases exhibited an abnormal strong effect of length (i.e., number of letters) on response ...
This study investigated sleep of children with autism and developmental regression and the possible relationship with epilepsy and epileptiform abnormalities. Participants were 104 children with autism (70 non-regressed, 34 regressed) and 162 typically developing children (TD). Results suggested that the regressed group had higher incidence of circadian ...
Developmental disabilities occurred in children who manifested transient neurologic abnormalities in early infancy. In an attempt to identify associated problems at an earlier age, the neuromotor and developmental progress of 33 children who had transient hypertonicity during early infancy was analyzed. At 2-3 years of age, various ...
Wistar Hannover rats, which are maintained by three animal breeders in Japan, were examined to obtain basic data on reproductive and developmental parameters. Untreated pregnant females were terminated on gestational day 20, and the fetuses were removed by cesarian section. The fetuses were counted, weighed and examined for morphological abnormalities. ...
A variety of brain structural abnormalities, which can be identified only by qualitative methods, have been shown to correlate with clinical presentation and course of schizophrenia. In the present study, MRI scans of 122 patients with DSM-IV schizophrenia and 81 non-psychiatric controls were evaluated. Among males, the frequency of CNS developmental ...
... website at http://www.epa.gov/pesticides/cumulative/. ... UF = 100X weight, tail developmental LOAEL = 650 ... FQPA SF = 1x abnormalities, delayed mg ...
It is well established that human diseases associated with abnormal immune function, including some common infectious diseases and asthma, are considerably more prevalent at younger ages. Although not established absolutely, it is generally believed that development constitutes ...
... J. E. and G. W. Bennett. Mortal. and developmental abnormalities induce by two juvenile hormone analogs on nymphal German cockroaches (Dictyoptera: Blatellidae). J. Econ. Entomol 225�227. 81.1988. ... per...
It is widely accepted that exposure to environmental factors during development can result in effects other than death, gross structural abnormality, or altered growth. One area of concern is the developing nervous system, which may be especially vulnerab...
It is widely accepted that exposure to environmental factors during development can result in effects other than death, gross structural abnormality or altered growth. ne area of concern is the developing nervous system, which may be especially vulnerable to environmental perturb...
... LEV-NC104 Developmental toxicity study with C1-INH in Sprague-Dawley rats ... Phase 1 (acute study-groups 1-4) � no abnormalities at doses from 0-400U/kg ...
Aicardi syndrome is a rare neurodevelopmental disorder characterized by agenesis of the corpus callosum, other developmental brain abnormalities, chorioretinal lacunae, and severe seizures. Current clinical knowledge is derived from small series that focus on these major defects. The authors perform...
Technology Transfer Automated Retrieval System (TEKTRAN)
... in the enamel surface possibly resulting from a developmental abnormality. Postcranial Remains Isolated plesiosaur ribs (NMV P180852, NMV ... Formation) in buccal and lateral views showing potential de...
... vitro-produced parthenogenetic oocytes may be responsible for developmental abnormalities in some of the 9.5-day-old fetuses, which were developed from the reconstructed oocytes containing ... with develo...
... fact sheets FAQ neurofibromatosis health resources inherited diseases Learning About Neurofibromatosis What is neurofibromatosis? What are the ... developmental abnormalities and/or increased chances of having learning disabilities. Other forms of NF, where the symptoms ...
... fundamental question in this context is whether the developmental abnormalities reported to date are specific to somatic cloning. ... of nuclear differentiation during development that leads to developmen...
... PubMedlguchi T, Sato T (2000) Endocrine disruption and developmental abnormalities of female reproduction. Am Zool 40: 402�411 ... ...
The First International Conference on Male-Mediated Developmental Toxicity, held in September 1992, reported that the spermatozoon can bring genetic damage into the oocyte at fertilization and thereby contribute to subsequent abnormal pregnancy outcomes. At that time, laboratory ...
... al., 1984; Hayes, 1991), egg jostling to avoid developmental abnormalities (Salthe and Mecham, 1974; Simon, 1983), and prevention ... clutches already affected by desiccation. The prevention of developmen...
... Animals produced from assisted reproductive technologies suffer from developmental abnormalities and early fetal death at a higher frequency ... is present in cloned animals that suffered from development...
... opening in the roof of the mouth (a cleft palate). In addition to skeletal abnormalities, individuals with otopalatodigital ... 2? actin ; atypical ; big toe ; camptodactyly ; cell ; chromosome ; cleft palate ; cytoskeleton ; developmental delay ; duct ; dysplasia ; gene ; hydrocephalus ; hypospadias ; ...
During 1998 and 1999, the NICHD staff engaged the scientific community in jointly developing a strategic plan to facilitate achieving its mission. The initial framework document for this plan, From Cells to Selves, highlighted four areas for immediate str...
Contents: Internal defenses of Crustacea; Cleaning symbiosis among California inshore fishes; Gray whales avoid the underwater sounds of killer whales; Killer whate sounds repel white whales; Developmental abnormalities of the flatfish Achirus lineatus re...
... et al. 2003; Smith et al. 2005). Various developmental abnormalities apparently arise from these epigenetic NT reprogramming errors, ... differences that predispose NT embryos to placentation failure, dev...
Angiopoietin-1 (Ang-1) and its receptor Tie-2, a trans-membrane tyrosine kinase uniquely expressed by endothelial cells, are essential to developmental angiogenesis. The phenotypic abnormalities shown by null mutation studies suggest that Tie-2 signaling ...
... 5�100 mg/kg body weight bisphenol-A (BPA). Each point contained 7 mice. *: P < 0.05 ... KB) Rudy Boonstra. (2004) Coping with Changing Northern Environments: The Role of the Stress Axis in Birds ... ...
... fmol/egg of HpDcr-MO2 resulted in severe developmental abnormalities (Fig. 5R�T), co-injection with 0.01 ... ...
... independent of temperature (Tables 1 and 2). However, developmental abnormalities increased with exposure to higher temperature during the refractory phase (data not shown). Tauber et al. (1986) stressed t...
... and a female) died at birth due to dystocia. These 2 calves were relatively overweight at birth ... 38]; however, they died as a result of dystocia and abnormal presentation in the absence of clinical .....
The National Institute of Child Health and Human Development (NICHD) seeks to ensure that every individual is born healthy, is born wanted, and has the opportunity to fulfill his or her potential for a productive life unhampered by disease or disability. ...
... double-crested cormorants (Phalacrocorax auritus) and Caspian terns (Hydroprogne caspia) of the upper Great Lakes 1986�1991: testing ... double-crested cormorants (Phalacrocorax auritus) and Caspian terns...
The purpose of this study was to examine the pectineus muscles of German shepherd and mongrel dogs to determine if abnormalities of this muscle exist. This report serves to describe a developmental myopathy with type II fiber hypotrophy in the pectineus m...
The authors have adopted the traditional approach with a systematic examination of a wide range of disorders. There is an introductory section on physics and instrumentation which is treated with considerable detail. Concise discussions of neoplastic, inflammatory, vascular, degenerative, and traumatic disorders of the brain and craniofacial area follow. Pediatric and ...
Intrahepatic cholangiocarcinomas were found at necropsy in two previously reported cases of congenital dilatation of the intrahepatic bile ducts. The nature of the developmental abnormality is discussed and compared with other forms of biliary dilatation. Slow-flowing bile for many years probably leads to cholangiocarcinoma.Images
Although abnormal electroencephalograms (EEG) are seen more frequently in mentally retarded individuals than in the rest of the population, there are few features of the EEG which correlate specifically with mental retardation. Observation of exaggerated ...
The aim of this study was to characterize the type, topography and severity of developmental changes in the brain of people diagnosed with autism. To detect global pattern of brain pathology, the entire brain hemisphere was embedded in celloidin or polyet...
introduces students to core areas of psychology including abnormal, developmental, industrial.S.) degree in psychology. This degree prepares undergraduate students for employment in applied settings or for graduate study in psychology and related fields. Students who choose not to continue toward a graduate
...thinking (not open to reason), alterations in memory, abnormalities of mood or affect (fear, alarm, terror, anger...anxiety to severe personality disorder (as distinguished from developmental) or almost complete personality disintegration...
reviews of theories, research and applications in developmental psychology. U 340S (PSYC 330S) Abnormal psychology. Review of ethical principles and professional standards of psychologists. Analysis every term. Prereq., graduate standing in the clinical psychology program and consent of instr. Review
Se in the form of sodium selenite is toxic to Xenopus laevis embryos and tadpoles continuously exposed to concentrations above 1 ppM. Concentrations of 2 ppM and above result in severe developmental abnormalities and increased mortality. Uptake and loss of radioactive Se from water are rapid, but depuration is not complete, indicating that some Se can ...
Conifer cones are reproductive structures that are typically of restricted growth and either exclusively pollen-bearing (male) or exclusively ovule-bearing (female). Here, we review two common spontaneous developmental abnormalities of conifer cones: proliferated cones, in which the apex grows vegetatively, and bisexual cones, which possess both male and ...
The looking behavior of children with pervasive developmental disorder (PDD) and age- and IQ-matched normal control children was studied using infrared oculography. Stimuli varying in complexity and topic were presented to test whether children with PDD have specific abnormalities in looking behavior to complex stimuli and/or to faces. All children showed ...
Sublethal abnormalities were examined in developing embryos of the winter flounder, Pseudopleuronectes americanus, as part of a study of its early reproductive success in Long Island Sound and two sites in Boston Harbor. These sites represented varying levels of anthropogenic contamination that were possibly affecting reproduction, as ascertained by chromosomal ...
Gross motor development (supine, prone, rolling, sitting, crawling, walking) and movement abnormalities were examined in the home videos of infants later diagnosed with autism (regression and no regression subgroups), developmental delays (DD), or typical development. Group differences in maturity were found for walking, prone, and supine, with the DD and ...
Structured AbstractPurpose of ReviewSummarize recent studies exploring the relationship between paternal and maternal environmental exposures to chemicals before, at the time of and after conception to adverse developmental outcomes including; preterm birth, death, structural and functional abnormalities and growth restriction.Recent FindingsRecent studies ...
Until recently, clinical dysmorphology was poorly considered in medicine and human genetics. However, the studies of children affected with multiple congenital anomalies syndromes lead to syndrome identification, prognosis and care for the affected children, and genetic counselling for the families. The identification of developmental genes involved in normal and ...
Sea urchin eggs were irradiated with /sup 137/Cs ..gamma.. rays at various stages of the mitotic cycle, and chromosomal aberrations at the first postirradiation mitosis and embryonic abnormalities at later developmental stages were examined. The radiosensitivity of the eggs to both endpoints varied in parallel with the mitotic stage at the time of ...
We report a case of sirenomelia sequence observed in an incident of preterm labor during the 29th gestational week. According to some authors, this syndrome should be classified separately from caudal regression syndrome and is likely to be the result of an abnormality taking place during the fourth gestational week, causing developmental ...
In this case study about a baby born with the genetic condition holoprosencephaly, students explore the “Sonic hedgehog” gene, signal transduction, and the ethics of body and tissue donation. The assignment involves students writing an informed consent document that explains the science behind this congenital abnormality. Designed for an upper-level ...
Two patients with schizophrenia had markedly abnormal neuroimaging studies; one was found to have a large, cystic cavum vergae, while the other demonstrated complete agenesis of the septum pellucidum with a monoventricular system. The increased prevalence of developmental abnormalities of midline forebrain structure in patients with ...
Embryos of the Sea Urchin Paracentrotus lividus were incubated for different periods of time in various concentrations of Zinc-ethylenebisdithiocarbamate (ZINEB) in artificial (or natural) sea water. Dramatic developmental modifications have been observed after 48 hour treatment with 0.4 ug/ml ZINEB solution. The abnormalities concern the formation of ...
A sternal cleft is a rare congenital and developmental disorder. In general, this disorder is associated with skeletal and extraskeletal abnormalities (eg, Cantrell syndrome), but isolated sternal clefts have also been reported. A sternal cleft with pectus excavatum is a rare congenital abnormality. We present a complete sternal cleft ...
Human newborns can suffer from neuro-developmental abnormalities, when they are born as preterms. With near infrared spectroscopy (NIRS) it is possible to investigate any brain disease occurring together with these neuro- abnormalities. The specific absorption properties of haemoglobin and oxygenated haemoglobin in the near infrared ...
NASA Astrophysics Data System (ADS)
A neuropathological study of autism was established and brain tissue examined from six mentally handicapped subjects with autism. Clinical and educational records were obtained and standardized diagnostic interviews conducted with the parents of cases not seen before death. Four of the six brains were megalencephalic, and areas of cortical abnormality were identified in four ...
containing terminal fist embryos was arrested at one of three distinct developmental stages and appeared un- linked to fist embryo morphogenesis. The -conglycinin seed storage protein gene promoter, normally active in cellularised wild-type endosperm, was inactive in fist en- dosperm, indicating abnormal
The synthetic surfactant, perfluorooctanoic acid (PFOA) is a proven developmental toxicant in mice, causing prenatal pregnancy loss, increased neonatal mortality, delayed eye opening, and abnormal mammary gland growth in animals exposed during fetal life. PFOA is found in the ser...
This article reviews recent evidence supporting a biological basis for developmental dyslexia. It concludes that the combined evidence demonstrating macroscopic morphologic, microscopic neuronal, and microstructural white matter abnormalities in dyslexia is consistent with a localization of the principle pathophysicological process to perisylvian ...
This paper summarizes research currently being conducted on the biologic underpinnings of learning disorders, particularly dyslexia. The research findings discussed are derived from studying neuroanatomic, neurophysiologic, neurogenetic, neuroimaging, and behavioral characteristics in animal models that exhibit developmental brain anomalies and learning disorders comparable to ...
This study evaluated cytogenetic and molecular parameters in 30 Brazilian youths with autism or other pervasive developmental disorders (PDD). The high frequency of chromosomopathies found support the hypothesis that PDDs may develop as a consequence to chromosomal abnormalities and justify the cytogenetic and molecular assessment during diagnosis in all ...
The present paper reviews the theoretical and empirical literature on children and adolescents with gender variant behaviors. The organizational framework underlying this review is one that presents gender behavior in children and adolescents as a continuum rather than as a dichotomy of normal versus abnormal categories. Seven domains are reviewed in relation to gender variant ...
Analysis of use of positron emission tomographic measurements of resting-state regional cerebral blood flow in 29 men, 10 of whom stuttered, did not support the idea that developmental stuttering is associated with abnormalities of blood flow at rest. Findings did suggest an essentially normal functional brain terrain with a small number of minor ...
Dyslexia in adults is associated with clinical signs of fatty acid deficiency K.E. Taylor,1 C Summary Developmental dyslexia is a complex syndrome whose exact cause remains unknown. It has been are consistent with the hypothesis that fatty acid metabolism may be abnormal in developmental dyslexia
Congenital absence of the long head of the biceps (LHB) tendon is a rare condition. The literature describes unilateral cases, associations with other congenital developmental anomalies, and associations with shoulder instability and SLAP tears. We present a case with bilateral absent LHB tendons and subacromial impingement pathology in a patient without a history of trauma or ...
Two male cousins are reported with arachnodactyly, selective aminoaciduria, congenital cataracts, cerebellar ataxia, and delayed developmental milestones, and a distant female relative with similar abnormalities. The syndrome is thought to be previously undescribed, though it has resemblances to Marinesco-Sj�gren and Marfan's syndromes. Images
PURPOSE:To study the lenticular problems in children presenting at an apex institute. METHODS:Retrospective analysis of records (< 14 years) of new lens clinic cases was done. RESULT:Of 1,047 children, 687 were males. Mean age at presentation was 6.35 � 4.13 years. Developmental cataract was seen in 45.6% and posttraumatic cataract in 29.7% of patients. Other ...
We studied seven children with CNS folate deficiency (CFD). All cases exhibited psychomotor retardation, regression, cognitive delay, and dyskinesia; six had seizures; four demonstrated neurological abnormalities in the neonatal period. Two subjects had profound neurological abnormalities that precluded formal behavioral testing. Five subjects received ...
Alternative pre-mRNA splicing plays a key role in the control of gene expression in both neurons and glial cells, and failure or dysregulation of these splicing events can cause developmental abnormalities and lead to the development of pathology. Schizophrenia is a common mental disorder that presents as a complex condition. Many factors, of genetic, ...
The growth and development of plants is regulated by several external and internal factors including auxin. Its distribution regulates several developmental processes in plants. Auxin molecules function as mobile signals and are involved in the spatial and temporal coordination of plant morphogenesis and in plant responses to their environment. The intercellular transport of ...
The authors present a cognitive-developmental theory of emotional awareness that creates a bridge between normal and abnormal emotional states. Their primary thesis is that emotional awareness is a type of cognitive processing which undergoes five levels of structural transformation along a cognitive-developmental sequence derived from ...
The transcriptional regulation orchestrating the development of the heart is increasingly recognized to play an essential role in the regulation of ion channel and gap junction gene expression and consequently the proper generation and conduction of the cardiac electrical impulse. This has led to the realization that in some instances, abnormal cardiac electrical function and ...
ObjectiveThe socio-communicative abnormalities of young children with Williams syndrome (WS) with limited language were compared to those of children with clinical diagnoses of Autism, Pervasive-Developmental Disorder � Not Otherwise Specified (PDD-NOS), or nonspectrum developmental disability.MethodParticipants were 30 children with ...
This study found abnormalities in multiple reproductive stages in captive American kestrels (Falco sparverius) when exposed to polychlorinated biphenyls (PCBs) through dietary and in ovo exposure. American kestrels laid eggs with environmentally relevant total PCB levels (34.1 micrograms/g whole egg wet weight) when consuming PCB-spiked (Aroclor 1248:1254:1260) food (5-7 ...
Smith-Magenis syndrome (SMS) is a multiple congenital anomaly, mental retardation (MCA/MR) syndrome associated with deletion of chromosome 17 band p11.2. As part of a multi-disciplinary clinical, cytogenetic, and molecular approach to SMS, detailed clinical studies including radiographic neurologic, developmental, ophthalmologic, otolaryngologic, and audiologic evaluations ...
Background:Developmental structural abnormalities of the thyroid gland are relatively rare. There are scanty reports of hemiagensis, dual and triple ectopia of the thyroid in the literatureMaterials and Methods:We did a retrospective analysis of 236 patients referred to us for Tc-99m Pertechnetate thyroid scan over period of four months (May 2010 to Sept ...
BackgroundGlaucoma is a blinding disease usually associated with high intraocular pressure (IOP). In some families, abnormal anterior segment development contributes to glaucoma. The genes causing anterior segment dysgenesis and glaucoma in most of these families are not identified and the affected developmental processes are poorly understood. Bone ...
Silver nanoparticles (AgNPs) have emerged as an important class of nanomaterials and are currently used in a wide range of industrial and commercial applications. This has caused increasing concern about their effects on the environment and to human health. Using Japanese medaka (Oryzias latipes) at early-life stages as experimental models, the developmental toxicity of silver ...
Quintozene is a fungicide containing the active ingredient, pentachloronitrobenzene (PCNB) that is used to control "snow mold" on golf courses in temperate regions of North America. In this study, quintozene and a formulation of quintozene widely used on golf courses, FFII were tested for toxicity to early life stages of the Japanese medaka, Oryzias latipes. For medaka exposed in static ...
The NTP has conducted developmental toxicity studies on more than 50 chemicals, often in multiple species. Several chemicals caused developmental toxicity in the absence of any toxicity to the mother. Although hazard to humans is determined by the level of exposure to the chemical and its inherent toxicity, those agents that selectively disturb the ...
Many paediatricians are now interested in applying the concepts, theories and methods of developmental psychology to clinical practice. The new understanding so obtained should enable abnormalities of clinical importance to be detected earlier; it should also provide means for evaluating the outcome of some disease processes and medical procedures more ...
