...findings. (a) Findings of, or findings suggesting, enlarged heart, tuberculosis, lung cancer, or any other significant...the most recent examination was interpreted to show enlarged heart, tuberculosis, cancer, complicated pneumoconiosis, and...
Code of Federal Regulations, 2010
and testing may reveal: Abnormal curvature of the spine (kyphoscoliosis) Cloudy cornea Heart murmur (aortic regurgitation) Inguinal hernia Liver enlargement Loss of nerve...
Science.gov Websites
and Tests Signs of ECD may include: An abnormal electrocardiogram (ECG) An enlarged heart Heart murmur Children with partial ECD, who have only a small VSD and normal valves, may...
... develop an enlarged heart temporarily because of a stress on your body, such as pregnancy, or because of a medical condition, such as ...
MedlinePLUS
Although almost every doctor daily carries out physical examination of the heart, there is little reliable research into the value of the conclusions. Inspection and palpation of the apex beat and percussion of the left heart border are important in diagnosing enlargement of the heart. If the dullness falls within ...
PubMed
Heart rate activity and computed tomographic measures of structural brain abnormalities were evaluated in 32 individuals with a genetic risk for schizophrenia (offspring of schizophrenic mothers). Heart rate activity was assessed in 1962 when the subjects were a mean age of 15.1 years. Diagnostic and computed tomography assessments ...
To investigate the hypothesis that embryologic abnormalities in the venous valves may be associated with abnormal cardiac development, we examined the right atrial morphologic characteristics in 20 hearts with underdevelopment of the right heart and 17 normal hearts. In the study group, 16 ...
Cardiac abnormalities were identified in patients with familial palmoplantar keratosis. All of them were descended from families on the Greek island of Naxos. Four families were studied and nine cases of palmoplantar keratosis were identified; seven of them showed symptoms and signs of heart disease. Cardiomegaly on chest x ray and electrocardiographic ...
retina (back of the eye) Decreased iduronate sulfatase enzyme in blood serum or cells Heart murmur and leaky heart valves Enlarged liver (hepatomegaly) Enlarged spleen...
We transiently expressed a proapoptotic protein, Nip3a, by a heart-specific BMP4 promoter in zebrafish embryos and generated two variants of embryos with abnormal heart phenotypes (A and B). Embryos with phenotype A heart defects showed hypoplastic or elongated ventricles, elongated or enlarged ...
BackgroundIn the elderly the diagnosis of chronic heart failure is often challenging and the availability of echocardiography can be limited. Plasma levels of NT-proBNP are valuable tools to diagnose patients with heart failure. However, the performance of this biomarker to detect cardiac abnormalities in the very elderly remains ...
PubMed Central
... for the heart. The heart becomes enlarged from pumping blood against the resistance. Some symptoms include chest ...
Chronic heart failure (CHF), the new epidemic in cardiology, is characterized by energetic failure of both cardiac and skeletal muscles. The failing heart wastes energy due to anatomical changes that include cavity enlargement, altered geometry, tachycardia, mitral insufficiency and abnormal loading, while skeletal ...
... FDA Drug Safety Communication: Abnormal heart rhythms associated with use of Anzemet (dolasetron mesylate). ...
Center for Drug Evaluation (CDER)
Because of an epidemiologic association of decreased risk of death from ischemic heart disease with moderate use of alcoholic beverages, and because numerous abnormalities found in people with ischemic heart disease are also found in animals deficient in copper, rats were fed a diet deficient in copper and were given either beer or ...
... the heart enlarges, it becomes less effective in pumping blood, which then leads to symptoms of heart ... the left ventricle of the heart and reduced pumping ability in individuals with DCM. Other recommended screening ...
... Blood leaks back through the valve, making your heart work less efficiently. Ebstein's anomaly may also lead to enlargement of the heart or heart failure. If you have no signs ...
Two children presented with sleep disturbances due to enlarged tonsils and adenoids. One child died during induction of anaesthesia, and postmortem examination showed hypertrophy of the right ventricle and atrium. As a result a prospective survey was carried out of children undergoing tonsillectomy or adenoidectomy, or both. During a nine-month period an electrocardiogram was ...
... help your heart contract in a more coordinated fashion A defibrillator that recognizes life-threatening, abnormal heart ...
... aortic root is when a segment of the aorta closest to the heart is enlarged. This is ... In this surgery, the dilated (enlarged) part of aorta and aortic valve are removed. They are replaced ...
... and enlargement at the beginning part of the aorta, the major vessel carrying blood away from the heart. If left untreated, an enlarged aorta can lead to hemorrhage and even death. This ...
... advise caution to a patient with an enlarged aorta, which is the major artery in the body. An enlarged aorta can occur in people with Marfan syndrome, Turner ...
... heart murmurs heard by their doctors at some point in their lives. People who have abnormal heart murmurs may have signs or symptoms of heart problems. Most abnormal murmurs in children are caused by congenital (kon-JEN-i-tal) heart defects . These defects are problems ...
A three-month-old puppy had ascites, but its heart was normal by auscultation. Abdominal ultrasonography revealed an enlarged liver, distended hepatic veins and a distended caudal vena cava. Doppler ultrasonography detected retrograde flow in the caudal vena cava and abnormally pulsatile flow in the hepatic veins and caudal vena cava. ...
In general, the spleen accompanied by abnormal abdomen is hypertrophied. However, if the spleen size is originally small, it is hard to detect the splenic enlargement due to abnormal abdomen by simply measure the size. On the contrary, the spleen size of a person having a normal abdomen may be large by nature. Therefore, measuring the ...
NASA Astrophysics Data System (ADS)
BACKGROUND: Mitral valve dysplasia syndrome is a unique form of left-sided heart disease characterized by aortic outflow hypoplasia, dilated left ventricle, dysplastic/incompetent mitral valve, and a restrictive/intact atrial septum. Patients with this constellation of abnormalities have been managed in a variety of ways with overall poor outcomes. ...
The dose-response relation of abnormal intestinal crypt-cell enlargement was observed after x-ray doses from 500 to 10,000 r. Enlargement of the largest intestinal crypt cells is a function of x-ray dose, being greater with increasing dose. Greatest enlargement was observed 48 to 60 hours after all doses ...
Energy Citations Database
A 21-year-old patient, in her first and regularly controlled uneventful pregnancy, was admitted to hospital due to lower leg edema, hypertension, proteinuria, and weight gain. Fetal death occurred the next day and a female nonhydropic fetus, 40 cm CH, 1460 grams, at 29-week gestation was delivered. An autopsy showed no visible gross abnormalities except in the ...
Atrial septal defects are a common congenital heart defect in humans. Although mutations in different genes are now frequently being described, little is known about the processes and mechanisms behind the early stages of atrial septal development. By utilizing morpholino-induced knockdown in the chick we have analysed the role of alpha myosin heavy chain during early ...
To evaluate the cardiac hypertrophy from chest radiograph images, radiologists usually examine the cardiothoracic ratio (frequently called CTR) which is a standard diagnostic index. The CTR is computed by the maximum transverse diameter of the heart shadow divided by the maximum transverse diameter of right and left lung boundaries. In this paper, we present a method to ...
... What's the connection? Complications (6) Thoracic aortic aneurysm Brain aneurysm Enlarged heart see all in Complications Lifestyle and ... dangers: Hypertension's effects on your body Enlarged heart Brain aneurysm Abdominal aortic aneurysm Thoracic aortic aneurysm Related Links ...
... What's the connection? Complications (6) Thoracic aortic aneurysm Brain aneurysm Enlarged heart see all in Complications Lifestyle and ...
OBJECTIVES: Immunological abnormalities in idiopathic dilated cardiomyopathy (DCM) include an increase in soluble interleukin (IL)-2 receptor, disease specific cardiac autoantibodies, an HLA-DR4 association, and familial aggregation of disease; however, cytokine profiles have not been defined. Serum concentrations of IL-2, IL-4, IL-10, and IL-12 were measured in patients with ...
... is a form of congenital heart disease. This x-ray shows an enlarged heart, a large liver, and ...
... may be needed if: You have symptoms The left ventricle of the heart is enlarged Heart function gets ... blood clots in people who also have atrial fibrillation.
... to the heart's main pumping chamber called the left ventricle. It then closes to keep blood from leaking ... to the heart's main pumping chamber called the left ventricle. (Click on the illustration to enlarge it.) Occasionally, ...
the child. During the exam, the doctor may find: Enlarged fingers and toes (clubbing) Heart murmur (an extra sound when listening to the heart) The doctor will diagnose...
Cardiomyopathy refers to diseases of the heart muscle. These diseases enlarge your heart muscle or make it thicker and more rigid than normal. In rare cases, scar tissue ...
of the heart (ventricular septal defect) Correcting a blood vessel that connects the aorta of the heart to the pulmonary artery (ductus arteriosis) Enlarging the flow from the...
OBJECTIVE: The purpose of this study was to prospectively evaluate electrocardiograms (ECGs) before and after running a half marathon to characterize the changes that occur after exertion. Echocardiograms were also done postrace on selected runners. METHODS: Volunteer runners older than 18 years completed a questionnaire detailing demographic and medical history. Prerace ECGs were performed at a ...
... weakness of the heart muscle ( cardiomyopathy ) and abnormal transmission of signals that regulate the heartbeat ( conduction abnormalities ...
... system for the identification of abnormal patterns in the ... fetal monitors record and display the fetal heart rate (FHR) and maternal uterine activity ...
DTIC Science & Technology
... Descriptors : *NEURAL NETS, *CLINICAL MEDICINE, *HEART RATE, *ABNORMALITIES, *FETUS, ALGORITHMS, SETTING(ADJUSTING ...
... hydrobromide, should no longer be used at doses greater than 40 mg per day because it can cause abnormal changes in the electrical activity of the heart. ...
OBJECTIVE: To examine the distribution pattern of intercellular junctions (the mechanically coupling desmosomes and the electrically coupling gap junctions) in hypertrophic cardiomyopathy (HCM) hearts showing myofibre disarray. DESIGN: Samples from six necropsied hearts were studied, representing the interventricular septum and the free walls of the left ...
... or fast abnormal heart rhythms, such as: Atrial fibrillation Heart block Sick sinus syndrome Supraventricular tachycardia Ventricular ...
The heart has an internal electrical system that controls the rhythm of the heartbeat. Problems can cause abnormal heart rhythms, called arrhythmias. There ...
The expression and function of embryonic myosin heavy chain (eMYH) has not been investigated within the early developing heart. This is despite the knowledge that other structural proteins, such as alpha and beta myosin heavy chains and cardiac alpha actin, play crucial roles in atrial septal development and cardiac function. Most cases of atrial septal defects and ...
Ten consecutive patients with tissue-proven amyloidosis, seven of whom presented with congestive heart failure, were found to exhibit intense diffuse uptake of technetium-99m-pyrophosphate (Tc-99m-PYP) on cardiac radionuclide imaging. The patients exhibited echocardiographic and systolic time interval abnormalities suggesting combined restrictive and ...
Premature infants in the NICU are often exposed to continuous loud noise despite research documenting the presence and damaging effects of noise on the preterm infant's development. Excessive auditory stimulation creates negative physiologic responses such as apnea and fluctuations in heart rate, blood pressure, and oxygen saturation. Preterm infants exposed to prolonged ...
Amyloid cardiomyopathy is characterized by non-dilated thick-walled left ventricular, thickening of interventricular septum and right ventricular free wall, biatrial enlargement associated with granular 'sparkling' appearance of the myocardium. Typically, decreased left ventricular compliance results in abnormal diastolic functions but left ventricular ...
Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome (or Hay-Wells syndrome) is a rare congenital malformation. Our first cases were a pair of female monozygotic twins with AEC syndrome at Srinagarind Hospital. In this study, we describe monozygotic female twins concordant for ankyloblephaon, ectodermal dysplasia and helical rim deformities, but discordant for cleft, syndactyly of ...
Ebstein's anomaly is a rare congenital heart disease abnormality in which the tricuspid valve leaflets do not attach normally to the tricuspid valve annulus. The effective tricuspid valve orifice is displaced apically into the right ventricle (RV), near the junction of the inlet and the trabecular parts of the RV. The authors present a retrospective study ...
... heart and detect previously unseen leakages through heart valves and subtle abnormalities that can lead to congestive heart failure," said Dr. Thomas. ...
NASA Website
Tetralogy of Fallot is a birth defect of the heart consisting of four abnormalities that results in insufficiently oxygenated ...
A change in the heart's normal electrical conduction system can result in an arrhythmia or irregular heartbeat. An arrhythmia can be an abnormally slow ...
Activating transcription factor 3 (ATF3) is a member of the CREB/ATF family of transcription factors. Previously, we demonstrated that the expression of the ATF3 gene is induced by many stress signals. In this report, we demonstrate that expression of ATF3 is induced by cardiac ischemia coupled with reperfusion (ischemia-reperfusion) in both cultured cells and an animal model. Transgenic mice ...
Heparin-binding EGF-like growth factor (HB-EGF) is first synthesized as a membrane-anchored form (proHB-EGF), and its soluble form (sHB-EGF) is released by ectodomain shedding from proHB-EGF. To examine the significance of proHB-EGF processing in vivo, we generated mutant mice by targeted gene replacement, expressing either an uncleavable form (HBuc) or a transmembrane ...
... the heart appeared globular in lateral aspect. The aorta was enlarged in the cranial area of the ... cone in the left lateral side of the aorta in the heart. This cone ventro-dorsally ran ... ...
NBII National Biological Information Infrastructure
...irremediable deformities likely to interfere with breathing or swallowing. Heart. Note murmurs and arrhythmias, and any history of an enlarged heart, congestive heart failure, or cardiovascular disease that is accompanied by syncope,...
Extraocular muscle enlargement can result from a wide variety of disease processes. Although observations of the pattern of muscle involvement, muscle shape and enhancement, superior ophthalmic vein and cavernous sinus enlargement, sinus and bony wall abnormalities, and proptosis can lead to a limited differential diagnosis in some ...
The Xe-133 ventilation pattern in congestive heart failure (CHF) was assessed using 24 inpatient ventilation/perfusion studies performed to rule out pulmonary embolism. Patients with histories of CHF, myocardial infarction (MI), and cardiomyopathy were included in the study. Frank pulmonary edema, pulmonary embolism, and other known lung diseases such as chronic obstructive ...
Six patients with decompensated cirrhosis of the liver underwent Tc-99m BIDA studies. All demonstrated 1) persistently high blood pool activity in the heart, lung, and soft tissue, 2) slow hepatic tracer uptake, 3) prolonged liver-to-bowel transit time, and 4) visualization of an enlarged spleen. Four of the six patients demonstrated evidence of ascites ...
Glycoproteins with asparagine-linked (N-linked) glycans occur in all eukaryotic cells. The function of their glycan moieties is one of the central problems in contemporary cell biology. N-glycosylation may modify physicochemical and biological protein properties such as conformation, degradation, intracellular sorting or secretion. We have isolated and characterized two allelic Arabidopsis ...
May 8, 2009 ... Dr. Rob Bryant examines a laboratory model of a cardiac resynchronization therapy device. Click image to enlarge. Rob Bryant, a senior ...
The experiment consists of eight samples of three different types of ... image enlargement of the heart and other organs, muscles and blood vessels. ...
... dangers: Hypertension's effects on your body Enlarged heart Brain aneurysm Abdominal aortic aneurysm Thoracic aortic aneurysm Related Links ...
... Ask a doctor before use if you have # heart disease # high blood pressure # thyroid disease # diabetes # trouble urinating due to an enlarged prostate gland ...
Center for Biologics Evaluation and Research (CBER)
Bluish color to the skin (cyanosis) Enlargement of the liver Swelling (distension) of the neck veins, indicating high right-heart pressures Swelling of the ankles The following...
Background: The heart may be involved in children affected with sickle cell disease (SCD) via several mechanisms. Principally, chronic anaemia increases cardiac output and may cause left ventricular enlargement and cardiac insufficiency. Aims: To investigate whether the heart also suffers from ischaemia in SCD, as has already been ...
Drosophila is a well recognized model of several human diseases, and recent investigations have demonstrated that Drosophila can be used as a model of human heart failure. Previously, we described that optical coherence tomography (OCT) can be used to rapidly examine the cardiac function in adult, awake flies. This technique provides images that are similar to echocardiography ...
Binary cardiac transgenic (Tg) overexpression of P2X(4) receptors (P2X(4)R) improved the survival of the cardiomyopathic calsequestrin (CSQ) mice. Here we studied the mechanism of rescue using binary P2X(4)R/CSQ Tg and CSQ Tg mice as models. Cellular and intact heart properties were determined by simultaneous sarcomere shortening (SS) and Ca(2+) transients in vitro and ...
Aorto-ventricular tunnel is a congenital, extracardiac channel which connects the ascending aorta above the sinutubular junction to the cavity of the left, or (less commonly) right ventricle. The exact incidence is unknown, estimates ranging from 0.5% of fetal cardiac malformations to less than 0.1% of congenitally malformed hearts in clinico-pathological series. Approximately ...
... FDA Drug Safety Podcast for Healthcare Professionals: Abnormal heart rhythms may be associated with use of Zofran (ondansetron). Listen to this Podcast. ...
The most widely used tracer for the study of the heart muscle is thallium-201. The principal advantage of radioactive tracers in the study of the heart is that they tell us about regional as well as an overall function. In some cases a regional abnormality may be detected before the overall function of the heart is ...
Increased hormone levels that are present during puberty and pregnancy are associated with localized or generalized gingival enlargement. This article reviews the gingival alterations that can occur during pregnancy and describes a case of generalized severe gingival enlargement associated with pregnancy and its management. A 36-year-old woman had severe ...
Copper (Cu) deficiency, induced in rats by suckling from Cu-deficient dams and by offering a semisynthetic low-Cu diet from weaning, resulted in cardiac enlargement. This enlargement was not due to accumulation of excess fluid in the heart but was characterized by mitochondrial hypertrophy as demonstrated by electron microscopy and ...
E-Mail update icon E-Mail Updates Reduce Text Size Enlarge Text Size Font Size National Heart Lung and Blood Institute Logo Accessible Search Form Advanced Search Search the NHLBI,...
... The most serious problem is enlargement of the aorta (the main blood vessel that carries blood away ... have problems in blood vessels other than the aorta. Diagram of the Heart and Aorta Types of ...
In this work the three most important non-invasive methods - X-ray pictures, electrocardiography and echocardiography - were compared as to their ability to evaluate the physiological heart enlargement as a result of physical training. Important also was ...
National Technical Information Service (NTIS)
...zone (decreasing R/S) left of V1 ; or (3) Congestive heart failure with signs of vascular congestion such as hepatomegaly...or equivalent enlargement of the transverse diameter of the heart, as shown on teleroentgenogram (6-foot film); or...
Code of Federal Regulations, 2011
"A pacemaker is a small device that's placed under the skin of your chest or abdomen to help control abnormal heart rhythms. This device uses electrical pulses to prompt the heart to beat at a normal rate."
NSDL National Science Digital Library
the heart and lungs with a stethoscope. Listening with a stethoscope may reveal abnormal heart sounds or a murmur. These sounds may change with different body positions. The pulse...
... heart to the rest of the body (the aorta). The signs and symptoms of Marfan syndrome vary ... syndrome have abnormalities of the heart and the aorta. Leaks in valves that control blood flow through ...
... Changes in the electrical activity of the heart (prolongation of the QT interval of the electrocardiogram [ECG]) � see Data Summary below � can lead to an ...
of oxygen in their blood and significant heart swelling. The doctor may hear abnormal heart sounds, such as murmur, when listening to the chest with a stethoscope. Tests that...
... high pressure in the veins of the lungs forces fluid into the air sacs. Fatigue occurs because the abnormal pericardium interferes with the heart's pumping action, so that the heart cannot pump enough blood ...
The major issues concerning cardiac catherization services are examined. Following an introductory section, focus is on the following: the heart and abnormalities of the heart; methods for cardiac diagnosis and evaluation; the indications for coronary dia...
Blood Pressure; Heart Rate and Rhythm Disorders; Hypoglycemia; Lactate; Nitrate; Cholesterol (Total and HDL); Abnormality in Fetal Heart Rate or Rhythm, Unspecified as to Episode of Care
ClinicalTrials.gov
We generated a transgenic mouse model expressing the apical hypertrophic cardiomyopathy-causing mutation ACTC E99K at 50% of total heart actin and compared it with actin from patients carrying the same mutation. The actin mutation caused a higher Ca(2+) sensitivity in reconstituted thin filaments measured by in vitro motility assay (2.3-fold for mice and 1.3-fold for humans) ...
... infections present at birth heart or lung defects chromosomal abnormalities and birth defects liver disease Is hydrops fetalis ... the newborn Congenital heart defects Cystic lung disease Chromosomal abnormalities Birth defects and congenital anomalies Liver disease Clinical ...
a stethoscope. The doctor may hear abnormal sounds in your lungs (called crackles), a heart murmur, or other abnormal sounds. You may have a rapid pulse. Your blood pressure...
The most distressing types of heart malfunction occur because of an abnormal rhythm of the heart. Cardiac arrythmias can be caused by abnormal rhythmicity of the pacemaker, electrolyte disturbances, blockage of the transmission of the electric impulse thr...
Presentations given at the Conference on Abnormal Functional Development of the Heart, Lungs, and Kidneys are documented in this publication. The meeting was sponsored by the U.S. Environmental Protection Agency and was held in Asheville, NC, May 11-13, 1983. In an attempt to car...
EPA Science Inventory
BackgroundThe GNB3 gene is expressed in cone but not rod photoreceptors of vertebrates, where it acts as the ? transducin subunit in the colour visual transduction process. A naturally occurring mutation �D153del� in the GNB3 gene causes the recessively inherited blinding phenotype retinopathy globe enlarged (rge) disease in chickens. GNB3 is however also expressed in most ...
... Teen pregnancy, problems ... heart abnormalities, you should generally not take stimulant drug products such as ... abused or been dependent on alcohol or drugs, or if ...
... Descriptors : *CARDIAC GLYCOSIDES, *ELECTROLYTES(PHYSIOLOGY), *HEART, *IONS, BIOCHEMISTRY, BIOSYNTHESIS, CELLS(BIOLOGY ...
... abnormal mitochondria in the myocardium we have not yet succeeded in obtaining convincing evidence of any functional impairment of the heart ...
... Various types of arrhythmias occur as a result of abnormalities in cardiac ... of Health and Welfare of Japan, Research and Development Grant for ...
Endocardial cushion defect is an abnormal heart condition which occurs during the development of the baby. In this condition there is ...
Amyloidosis occurs when abnormal proteins build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs ...
The clinical and pathological manifestations of multiple sclerosis are due to areas of demyelination which occur throughout the white matter of the central nervous system. MRI of the brain frequently shows abnormalities in the hemispheric subcortical white matter; these are demonstrable in the majority of patients and support the clinical diagnosis of multiple sclerosis. Our ...
Submicroscopic deletion of the terminal part of the short arm of chromosome 6, including 6p25, leads to developmental retardation, hearing impairment, ocular dysgenesis, and dysmorphic features. We diagnosed 3 patients referred because of white matter abnormalities of unknown origin. MR imaging showed multifocal areas of abnormal signal and ...
Signal transduction via guanine nucleotide binding proteins (G proteins) is involved in cardiovascular, neural, endocrine, and immune cell function. Regulators of G protein signaling (RGS proteins) speed the turn-off of G protein signals and inhibit signal transduction, but the in vivo roles of RGS proteins remain poorly defined. To overcome the redundancy of RGS functions and reveal the total ...
Mitral reguritation is a relatively common finding in coronary heart disease. In this series of 127 patients, selected with a view to coronary or left ventricular surgery on the basis of severity of symptoms, the incidence was 39 (31%). Mitral regurgitation is significantly more common in patients with a history or electrocardiographic evidence of previous myocardial ...
An unusual case in which a computed tomogram demonstrated abnormal, enlarged vessels in the right lower lobe of the lung and suggested an arteriovenous malformation is presented. A scintiangiogram showed abnormal systemic supply to this area in the aortic phase. Contrast angiography demonstrated hypertrophy of the right inferior ...
The P-wave is notched, wider than 0.12s, and has a prominent negative (posterior) component in V1 - all criteria for left atrial abnormality or enlargement (LAE). The PR interval >0.20s. Minor ST-T wave abnormalities are also present.
Mice mutant for the presynaptic protein Bassoon develop epileptic seizures and an altered pattern of neuronal activity that is accompanied by abnormal enlargement of several brain structures, with the strongest size increase in hippocampus and cortex. Using manganese-enhanced magnetic resonance imaging, an abnormal brain ...
Combination of arterial hypertension (AH) and metabolic disorders accelerates development of organic lesions in target organs. As shown in recent prospective studies, myocardial hypertrophy rate closely correlated with severity of metabolic disturbance. The thickness of interventricular septum and posterior wall show stronger dependence of severity of metabolic disorders than left ventricular ...
Placentae with mesenchymal dysplasia (PMD) are typically larger than average and show cystic areas on ultrasonography. Fetal outcomes are variable and are often associated with growth restriction. However, enigmatically, some associated fetuses show signs of Beckwith-Wiedemann syndrome (BWS). PMD has recently been shown to result from androgenetic (complete paternal uniparental disomy) chimerism ...
A male CD-1 mouse from a segment I reproduction toxicity study died at the age of fifteen weeks. At necropsy, the thymus was abnormally enlarged and virtually obliterated the thoracic cavity. Histopathological examination of thymus revealed abundant cell population consisting of mature lymphocytes and few lymphoblasts arranged in cords and sheets. ...
The nature of the defects that shorten the effective lifespan of red blood cells in the circulation and which gave rise to anemia, jaundice and to spleen, liver and heart enlargement are studied because they so closely parallel inherited hemolytic anemias in man. In mice, ''hemolytic disease'' initiated by the ja, sph, ...
Electrocardiologic criteria of left ventricular enlargement do not take into consideration the eventuality of asymmetric hypertrophy. Since experimental techniques for production of this condition are not available, computer modeling was utilized to study its electrocardiologic manifestations. A computer model of human ventricles with analytically defined geometry, consisting ...
A 41-year-old woman with no modifiable coronary risk factors presented with a progressive exertional dyspnea. Chest radiography showed an enlarged cardiac silhouette with reinforced pulmonary vasculature in bilateral lower lung fields and both pleural effusion. Echocardiography revealed a dilated, globally hypokinetic left ventricle with an ejection fraction of 40%. Multislice ...
examination may show: Abnormal heart sounds Feeling of a pulse over the breastbone Heart murmur on the right side of the heart Larger-than-normal veins in the neck Leg...
Left ventricular hypertrophy (LVH) means literally, overgrowth of the left side of the heart. However the term is generally limited to an abnormal increase in the mass of the left ventricular heart muscle. In pathological terms, this means an increase in ...
... fungi, or other germs invade your bloodstream and attach to abnormal areas of your heart. The infection can damage your heart and cause ... affect people in different ways, the signs and symptoms vary. IE also can cause ... parts of the body besides the heart. If you're at high risk for IE, ...
serious conditions that can lead to light-headedness include: Heart problems, such as a heart attack or abnormal heart beat Stroke Bleeding inside the body Shock (extreme drop in...
...associated swelling, warmth and pain, in general is considered...an inflammation of the heart muscle (myocardium). Pericarditis...inflammation of both the heart muscle and its covering. The inflammation...generally manifests with chest pain, abnormal heart sounds...
...any manifestation of joint pain, any abnormality of heart action or heart sounds, any urinary findings of casts, or any cough...permit service connection of arthritis, disease of the heart, nephritis, or pulmonary disease, first...
... Doppler. Collectively, these results support the hypothesis that defects at the maternal-fetal interface are primary causal ... C and D). enlarge figure FIG. 3. Anatomical defects in the fetal labyrinth ...
... 8, 12, 13]. Other abnormalities such as enlarged umbilical cords [8, 14] and oversized fetuses [2, 14] ... Fissorea. (2004) Patterns of Intracellular Calcium Oscillations in Horse Oocytes Fertilized by I...
causing pronounced enlargements in the liver and spleen, and abnormalities in blood flow through flukes, though, by being dioecious (having separate male and female worms) and dimorphic (with the two]. Nutrients are then conveyed to the liver via the hepatic portal system. Most species of schistosomes live
E-print Network
Waldmann in 1961 redefined primary protein-losing gastroenteropathy and renamed the condition 'lymphangiectasia'. This abnormality, usually seen in infancy, is characterized by enlargement of folds and signs of hypersecretion in the small bowel. Enlargeme...
Giant left atrium syndrome can occasionally occur in patients with rheumatic mitral valve regurgitation and can be responsible for oesophagus and/or airways compression. Abnormally enlarged left atriomegaly creates unusual right chest opacification on radiographs. PMID:21881448
with a pituitary tumor: Abnormal nipple discharge Absent menstruation (periods) Breast development in men Enlarged hands, feet Excessive body hair Facial changes Low blood...
Brain lesions Basics Multimedia Definition Causes When to see a doctor Connect with others who've been ... Clinic staff CLICK TO ENLARGE MRI showing a brain lesion Brain lesions are abnormal areas of tissue ...
Data suggest that heart failure (HF) in Afro-Caribbean patients may be more often associated with preserved left ventricular (LV) systolic function, LV hypertrophy, and probable LV diastolic dysfunction than in other populations. Echocardiographic results on all patients referred for HF in a contemporary Afro-Caribbean population were reviewed, comparing findings in patients ...
This electrocardiogram image is part of the Health Education Assets Library collection. The picture shows Left Atrial Enlargement, wich is best seen in V1 with a prominent negative (posterior) component measuring 1mm wide and 1mm deep. There are also diffuse nonspecific ST-T wave abnormalities which must be correlated with the patient's clinical status. ...
There is controversy regarding the influence of the benign enlargement of the subarachnoid space on intracranial injuries in the field of the shaken baby syndrome. In the literature, several terminologies exists to define this entity illustrating the lack of unicity on this theme, and often what is "benign" enlargement is mistaken with an old subdural ...
To determine resting myocardial perfusion in 30 patients with aortic valve disease (AVD) TI-201 emission computer tomography (ECT) studies and heart catheterization were performed. 16 patients had a predominant aortic regurgitation (AR); an aortic stenosis (AS) was found in 14 patients at catheterization. Perfusion defects were documented in 10 of 16 patients with AR, and in 5 ...
The frequency and types of malformations are described that were encountered during the spring of 1983 in a natural population of aquatic birds exposed to agricultural drainwater ponds and food items containing high concentrations of selenium in central California. A total of 347 nests of aquatic birds containing 1,681 eggs was selected for study at Kesterson Reservoir located in the Kesterson ...
USGS Publications Warehouse
A three-year-old white female with acute promyelocytic leukemia developed persistent fever after successful induction-remission therapy; many large monilial abscesses were later found in the grossly enlarged spleen. Although the technetium/sup 99M/-sulfur colloid scan prior to splenectomy suggested only a slight abnormality of the spleen, the ...
The aim of the study was to compare the prevalence of predefined ECG abnormalities, compiled from the literature, and of increased electrocardiographic myopathy indices (QT/PQs, P/PQs, R/S) among myopathy patients, patients with coronary heart disease and healthy subjects. ECGs from 27 myopathy patients, 35 patients with coronary heart ...
We report a case of successful stent-graft endovascular treatment of a huge traumatic carotid-jugular fistula with a pseudoaneurysm that had resulted from a bullet injury. A 77-year-old man with a pulsatile neck mass came to our hospital complaining of dyspnea and chest pain at rest; about 58 years ago, a gunshot accident had inflicted a penetrating bullet wound on the right side of his neck. ...
Microcystins (MCs) are hepatotoxic heptapeptides released into water during or on senescence of cyanobacterial blooms. This review details the different effects of the MCs on fish and discusses their potential consequences in aquatic food webs. In early life stages, exposure to MCs causes, in a dose-dependent manner, perturbations to embryonic hatching, decrease in survival and growth rate, as ...
The coxsackievirus-adenovirus receptor (CAR) is a cell contact protein on various cell types with unknown physiological function. It belongs to a subfamily of the immunoglobulin-superfamily of which some members are junctional adhesion molecules on epithelial and/or endothelial cells. CAR is dominantly expressed in the hearts and brains of mice until the newborne phase after ...
Thirteen children, age 1.9 to 14.8 years with documented sickle cell disease, underwent echocardiographic assessment of cardiac status while on and off periodic hypertransfusion therapy (HTX). Two to three units of washed packed red blood cells were transfused every 2-4 weeks in children with splenic sequestration crises, cerebrovascular accidents (CVA), aseptic necrosis of the femoral head, and ...
Computed tomography (CT) of the adrenal glands was performed on seven patients who had histologically proved disseminated histoplasmosis. All seven patients showed some degree of adrenal gland abnormality. The range of CT findings included minimal enlargement with faint flecks of calcium, moderate enlargement with focal low attenuation ...
Eleven month old cardiomyopathic hamsters, which have enlarged hearts and anasarca, were given access to either an ethanol vehicle or an ethanol-digoxin solution in addition to a second water bottle. In comparison to controls, treated hamsters survived and showed significant amelioration of the pathological syndrome of heart failure. ...
Congestive heart failure (CHF) is a leading cause of morbidity and mortality. CHF is marked by atrial and ventricular enlargement and reduced cardiac contractility, as well as an association with an increased incidence of atrial and ventricular arrhythmias and sudden cardiac death. Dysfunctional ion channel function is one of the major underlying ...
Several publications considering anatomical, histological, pathological, electrocardiographic, vectorcardiographic, and electrophysiologic studies have shown that the left bundle branch splits into three fascicles or in a "fan-like interconnected network" in the vast majority of human hearts. The left His system is trifascicular with a left anterior, a left posterior, and a ...
The autopsy findings of an adult patient with 21-hydroxylase deficiency are presented. Genetic analysis of the 21-hydroxylase gene (CYP21A2) was performed for accurate diagnosis of congenital adrenal hyperplasia (CAH), and bilateral testicular tumors were characterized. We report a 29-year-old Japanese man who was diagnosed with CAH (21-hydroxylase deficiency) in infancy and had continued steroid ...
Abnormal cardiovascular responses to exercise in heart failure contribute significantly to the morbidity and mortality in the patient population. These abnormal responses may be the result of peripheral impairment in the skeletal muscle and the neurons that innervate the muscle. We present the current literature on the role of muscle ...
The sonographic finding of an enlarged fetal bladder may simply be a transitory normal variant, but it may also be secondary to reflux or to obstructive, neurogenic, or myopathic causes. In this report, we describe the cases of 3 fetuses with an enlarged bladder, each of which had a different cause. The first fetus had posterior urethral valve obstruction, ...
In tests on 80 rabbits and 20 dogs exposed to 500 and 250 r of x radiation, respectively, disturbances in breathing rhythm and development of myocardium infract were quite pronounced. Considerable enlargement of capillary vessels, hemorrhage into the heart muscle, and an enlargement of Thebesian vessels were also observed. ...
of this disorder in humans. Here we report a model of heart failure based on the disruption of genes that regulate- activity in mice. Am J Physiol Heart Circ Physiol 283: H1838�H1845, 2002. First published July 26, 2002; 10 in the development and progression of heart failure. 2-adrenergic receptor; knockout mice; ...
SynopsisHeart failure is defined as the pathological state in which the heart is unable to pump blood at a rate required by the metabolizing tissues or can do so only with an elevated filling pressure. Heart failure in adults most frequently results from the inability of the left ventricle to fill (diastolic performance) and/or eject ...
Tests Possible signs: Enlarged lymph glands Fatty stools Gastrointestinal (GI) bleeding Heart murmur Swelling in body tissues (edema) Tests to diagnose Whipple's disease may...
hospitals filled quickly with febrile and delirious men. Just two weeks into the epidemic, the hospital case include enlargement of the spleen, pneumonia, inflammation of the heart (myocarditis), delirium condition, febrile patients could not be transported to larger, rear-area medical facilities. Mortality
... abdominal and thoracic radiographs were taken. An enlarged cardiac silhouette was noted. Transcutaneous echocardiogram of the heart ... drainage. Due to concern about the use of cardiac medications in pat...
From vegetative seed planted each year, potatoes arise, enlarge and are harvested. This cycle of regeneration, maturation and rest is at the heart of the potato production industry. At all points in the cycle, there are benefits that can be derived from continued research on potato storage....
Technology Transfer Automated Retrieval System (TEKTRAN)
... Quintner. (2011) An Evolutionary Stress-Response Hypothesis for Chronic Widespread Pain (Fibromyalgia Syndrome). Pain Medicineno-noOnline publication date: 1- ... ...
Five experiments were conducted to determine the effect of adding silver acetate or nitrate to practical diets on growth of Large White turkey poults and incidence of pathological signs. The highest level of silver (900 p.p.m.) depressed growth rate, reduced packed cell volume, slightly reduced hemoglobin level and caused cardiac enlargement. The high silver level also induced ...
The nature of the defects that shorten the effective lifespan of red blood cells in the circulation and which gave rise to anemia, jaundice and to spleen, liver and heart enlargement are studied because they so closely parallel inherited hemolytic anemias...
... Mayo Clinic staff CLICK TO ENLARGE The liver Hereditary hemochromatosis (he-mo-kro-mah-TOE-sis), an ... your liver, heart and pancreas. If you have hereditary hemochromatosis, the stored iron damages these organs, leading ...
... He is survived by his wife, Nancy, two children, four grandchildren and a brother. Memorials may be made to the American Heart Association or to http://www.CaringBridge.org. enlarge figure H. Graham Purc...
... of the heart trMesV mesencephalic trigeminal tract uc umbilical cord V trigeminal nerves or root V1 ophthalmic ... pf), but grow into the wall of the umbilical cord (uc). The region labeled �C� is enlarge...
...Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES...used to create or enlarge the atrial septal defect found in the heart of certain infants. (b) Classification. Class...
...heart disease, high blood pressure, thyroid disease, diabetes, or difficulty in urination due to enlargement of the prostate gland unless directed by a doctor.� (3) �Do not use this product if you have ever been hospitalized for asthma or if you...
. Keywords: Heart failure; Calcium; Contractility; Myocardial contraction; Sarcoplasmic reticulum 1 to impaired cardiac contractile reserve and abnormal exercise tolerance among individuals with heart failure myocardium was obtained from patients with end- stage heart failure undergoing cardiac transplantation ...
In the present study, the authors report evidence that the existence of premature ventricular contractions increases the embedding dimension of the cardiac dynamics. They also analyze patients with congestive heart failure, a severe clinical condition associated with abnormal left ventricular function. Results also show an increase in the embedding ...
Two cases of pediatric patients with heart failure are presented. One child presented with vomiting and the other a child with a history of asthma who had respiratory distress. Though their presenting complaints are common, the diagnosis was made based on careful examination and consideration of abnormal findings. Abnormal vital signs ...
In the study of pathophysiological mechanisms in growth abnormalities of the juvenile knee in arthritis an animal model in dogs was developed. Arthritis was induced by intra-articular injections of Carrageenan. Prominent growth changes were enlargement of the distal femoral epiphysis, patellar squaring and decreased endochondral and appositional growth of ...
in optic atrophy, or a deep red color, enlargement, and blurred edges in papilledema. Blood vessels may to extract both normal and abnormal retinal objects. The normal objects in retinal images include blood such as retinal blood vessels [6, 4] and the optic nerve [5]. Abnormal objects have also been extracted, including
Parasympathetic control of the heart via the vagus nerve is the primary mechanism that regulates beat-to-beat control of heart rate. Additionally, the vagus nerve exerts significant effects at the AV node, as well as effects on both atrial and ventricular myocardium. Vagal control is abnormal in heart failure, ...
Adults with congenital heart disease (CHD) are an increasing population requiring cardiac operations. To date, the perioperative risk factors for this group have not been identified. This study aimed to identify clinical, morphologic, and hemodynamic risk factors for an adverse outcome. This study retrospectively analyzed a cohort of 500 patients (ages >16�years) who ...
Techniques for heart scanning using $sup 201$Tl and /sup 99m/Tc pyrophosphate are discussed. Thallium-201, produced artificially in a cyclotron, concentrates in normal heart muscle but not in abnormal tissue. Technetium-99m is deposited in mitochondria of heart cells that are irreversibly damaged. The ...
The mass effect of nephromegaly in patients with autosomal dominant polycystic kidney disease may cause pain and symptoms by compressing the alimentary tract, lungs, and heart. Conventional therapies exist to contract enlarged polycystic kidneys including surgical and interventional procedures. A surgical nephrectomy is often difficult to perform in ...
Function follows form and this maxim provides an understanding of the pathophysiology of congestive heart failure following myocardial infarction. The heart fails as it enlarges and becomes more spherical. Surgical methods to treat dilated ischemic cardiomyopathy have evolved and been applied to thousands of patients worldwide. Known ...
Obstructive sleep apnea linked to blood vessel abnormalities American Heart Association Rapid Access Journal Report Study Highlights : Sleep apnea can cause changes in blood vessel function that reduces blood supply to ...
abnormalities Microcephaly (- 3 SD) Scaphocephaly - - Scaphocephaly Metopic craniostenosis Heart defects ASD Cranial abnormalities - Microcephaly - HC at +1.66SD at 8 years - Macrocrania inserm-00541962,version1
... risk for a heart attack is low. Why did the researchers do this particular study? To see ... participants with and without abnormal lipid levels. What did the researchers find? Participants with worse lipid levels ...
... That means the baby's blood alcohol level stays elevated longer than the mother's. This is very dangerous, ... during pregnancy may also result in: Abnormal heart structure Abnormal brain structure Behavior problems Complications seen in ...
Five cases of supravalvular aortic stenosis (SAS) diagnosed by heart catheterization were studied in the Instituto Nacional de Cardiologia of Mexico. The clinic and laboratory data of interest of the differential diagnosis with other forms of obstruction of the left ventricle as follows: 1. Three cases had mental retardation and "elfin" face (SAS with specific psychophysical ...
In order to assess left ventricular function, measurements of left ventricular internal dimension and its rate of change have been made by echocardiography in 7 patients with myotonic dystrophy and the three children of one of them, who were clinically normal but had abnormal muscle biopsies. Electrocardiograms and systolic time intervals were also recorded in all. Only one ...
Simultaneous 111In-DPTA and metrizamide CT cisternography correlated closely in the qualitative imaging of cerebrospinal fluid (CSF) dynamics in 9 normal patients and in 11 patients thought to have communicating hydrocephalus. CSF clearance of both tracers was similar; significant absorption occurred in the spinal dural sac. Although delayed elevated serum iodine levels correlated highly with ...
Simultaneous /sup 111/In-DTPA and metrizamide CT cisternography correlated closely in the qualitative imaging of cerebrospinal fluid (CSF) dynamics in 9 normal patients and in 11 patients thought to have communicating hydrocephalus. CSF clearance of both tracers was similar; significant absorption occurred in the spinal dural sac. Although delayed elevated serum iodine levels correlated highly ...
Possible Complications Babies born with tracheomalacia may have other congenital abnormalities such as heart defects, developmental delay, or gastroesophageal reflux....
... add a controlled (eg cohort or case control) observational sub-study of abnormal pregnancy outcomes including congenital anomalies, congenital heart disease (eg ...
... showed the devices. ability to adequately present abnormal heart and breath sounds in 90 to 95 dB SPL. By their design ...
High Blood Pressure. Screening. Colorectal. Screening. Employee. Assistance ... on heart disease, exercise, diet, and smoking. People with abnormally high ...
... the biological role of CrkL during development in conjunction ... CELLS(BIOLOGY), GENETICS, HEART, ABNORMALITIES, PERIPHERAL NERVOUS ...
Electrolyte abnormality Emotional problems (depression or feeling useless) Head injury (subdural hematoma) Heart attack, pulmonary embolism, stroke Infection (including...
