... A genetic abnormality results in abnormal transport of amino acids in the kidney. The high levels of the amino acid cystine in the urine lead to stone ...
MedlinePLUS
...to measure magnesium levels in serum and plasma. Magnesium measurements are used in...treatment of hypomagnesemia (abnormally low plasma levels of magnesium) and hypermagnesemia (abnormally high plasma levels of magnesium). (b)...
Code of Federal Regulations, 2011
Radiological and Environmental Research Division annual report, July 1972-June 1973. A detailed study of both stable and unstable chromosome abnormalities in a single patient with a body burden of /sup 226/Ra is presente This patient was selected for detailed study because he had been the subject of previous detailed cytogenetic analysis, and was examined for evidence ...
Energy Citations Database
BackgroundMost studies on risk factors for development of coronary heart disease (CHD) have been based on the clinical outcome of CHD. Our aim was to identify factors that could predict the development of ECG markers of CHD, such as abnormal Q/QS patterns, ST segment depression and T wave abnormalities, in 70-year-old men, irrespective of clinical ...
PubMed Central
This caused an abnormally high level of static friction, which the computer read as mass. When it tried to compensate by increasing vibration, ...
NASA Website
... Page 8. FEBRUARY 2009 7 Diabetes mellitus is a chronic metabolic disorder that leads to abnormally high levels of glucose in the blood. ...
DTIC Science & Technology
Normally a balance of bile salts, lecithin and cholesterol keep gallstones from forming. If there are abnormally high levels of bile salts or, more commonly, cholesterol, stones can form. ...
... Accession Number : ADD117511. Title : On the Distribution of Martensite with Abnormally High Tetragonality,. Corporate Author : ...
Human neutrophils by a chemiluminescence assay exhibit diminished phagocytic activity in the presence of abnormally high levels of the serum metabolite acetoacetate. These findings, along with our previous evidence demonstrating myeloperoxidase inhibition by acetoacetate, implicate metabolic ketosis in the inhibition of neutrophil ...
Simultaneous 111In-DPTA and metrizamide CT cisternography correlated closely in the qualitative imaging of cerebrospinal fluid (CSF) dynamics in 9 normal patients and in 11 patients thought to have communicating hydrocephalus. CSF clearance of both tracers was similar; significant absorption occurred in the spinal dural sac. Although delayed elevated serum iodine levels ...
PubMed
Simultaneous /sup 111/In-DTPA and metrizamide CT cisternography correlated closely in the qualitative imaging of cerebrospinal fluid (CSF) dynamics in 9 normal patients and in 11 patients thought to have communicating hydrocephalus. CSF clearance of both tracers was similar; significant absorption occurred in the spinal dural sac. Although delayed elevated serum iodine levels ...
Receipt of an abnormal cervical smear result often generates fear and confusion and can have a negative impact on a woman's well-being. Most previous studies have focussed on high-grade abnormal smears. This study describes the psychological and psychosocial effects, on women, of having received a low-grade ...
Two hundred and four children and infants from Argenton and Boolaroo were surveyed for blood lead and hemoglobin levels. None of the children surveyed showed an abnormally high blood lead level, or low hemoglobin level, and none of the potentially high exposure groups had ...
Gallium 67 citrate scans and serum angiotensin converting enzyme (ACE) levels were obtained in 54 patients with sarcoidosis and analyzed in relation to clinical manifestations. 67Ga scans were abnormal in 97% of patients with clinically active disease (n = 30) and in 71% of patients with inactive disease (n = 24). Serum ACE levels were ...
Gallium 67 citrate scans and serum angiotension converting enzyme (ACE) levels were obtained in 54 patients with sarcoidosis and analyzed in relation to clinical manifestation. /sup 67/Ga scans were abnormal in 97% of patients with clinically active disease (n = 30) and in 71% of patients with inactive disease (n = 24). Serum ACE ...
/sup 67/Ga citrate scans and serum angiotensin converting enzyme (ACE) levels were obtained in 54 patients with sarcoidosis and analyzed in relation to clinical manifestations. /sup 67/Ga scans were abnormal in 97% of patients with clinically active disease (n . 30) and in 71% of patients with inactive disease (n . 24). Serum ACE ...
The Defense Waste Processing Facility (DWPF) will be used by the Department of Energy to process high level liquid radioactive waste into a stable and manageable solid form. The facility requires a performance-based operator training program to satisfy DOE orders and guidelines. The control room operator training portion of this program is conducted on the ...
It has been demonstrated that patients on highly active antiretroviral therapy are at increased risk for developing metabolic abnormalities that include elevated levels of serum triglycerides and low-density lipoprotein cholesterol and reduced levels of high-density lipoprotein cholesterol. ...
Second trimester maternal serum screening can identify high risk pregnancies and fetuses at risk for birth defects (in addition to those in the standard interpretation). The purpose of this study was to quantify such risks to improve counseling. We compared outcomes of 692 pregnancies that had abnormal levels of at least one analyte ...
Plasma prorenin is abnormally high, whereas renin is normal or even low, in many patients with long-standing diabetes mellitus complicated by microvascular disease. Nephropathy or autonomic neuropathy has been put forward as a cause. We found that in 223 consecutive diabetics prorenin correlated positively with serum creatinine, the presence of ...
Most of what is known about the implications of endocrine disrupting chemicals (EDCs) in the environment is site- or compound-specific. There are numerous reports of gonadal histological abnormalities, alterations in sex ratios, and high vitellogenin protein levels in fish below ...
EPA Science Inventory
This Week in The Journal F Cellular/Molecular Neuroprotective Growth Factors for Parkinson to grow and decreases in their susceptibil- ity to inhibition of growth by myelin. Un- derstanding defects, and abnormally high plasma levels of T3. Surprisingly, mice lacking Mct8 show no overt behavioral
E-print Network
In recent years the maximum level of induced interference current which can normally be expected in instrumentation systems has been found to be in the region of 100mA rms. However, in the course of investigating interference problems, abnormally high lev...
National Technical Information Service (NTIS)
The presence of abnormally high levels of the radioactive isotope of iodine, (sup 125)I, has been discovered in the thyroid glands taken from swans found on the Rivers Thames and Trent. The sources of activity have been traced to sewage outfalls into the ...
Serum lipid abnormalities were evaluated in 53 patients (40 men and 23 women) undergoing maintenance hemodialysis and 22 non-uremic patients (14 men and 8 women) with the nephrotic syndrome. Serum levels of cholesterol, triglycerides and high-density-lipo...
As part of the safety assessment in the design of the glass melter for large-scale immobilization of high-level radioactive wastes, structural considerations of the containment shell include its dynamic responses to abnormal loading conditions such as tha...
... such as aging, ischemia, hyper- oxia, or exposure to ionizing radiation, free radical levels can become abnormally high. Free radicals have been ...
Abnormalities in the expression and signaling pathways downstream of the epidermal growth factor receptor (EGFR) contribute to the progression, invasion, and maintenance of the malignant phenotype in breast cancer. EGFR is expressed at high levels in at l...
Dialysis dementia is a progressive and usually fatal neurologic syndrome in patients being treated with chronic hemodialysis. Such patients often have elevated levels of A1+3 in brain, and the high brain A1+3 might cause dialysis dementia. Studies have be...
Serial determinations of plasma dihydroxyphenylalanine (dopa) in 16 Parkinson's disease patients receiving levodopa showed a negative correlation between plasma dopa levels and disability scores among patients who exhibited daily fluctuations of signs and symptoms. This suggests that the amount of levodopa delivered to the brain from the periphery is of major importance in the ...
Patients at high risk for sudden death often exhibit complex heart rhythms in which abnormal heartbeats are interspersed with normal heartbeats. We analyze such a complex rhythm in a single patient over a 12-h period and show that the rhythm can be described by a theoretical model consisting of two interacting oscillators with stochastic elements. By ...
In a previous report, the authors showed that lack of acclimation to nitrite can result in abnormally high levels of methemoglobin in nitrite-exposed channel catfish. They also observed abnormal methemoglobin levels in fish when concurrent bacteremias are present. Enteric Septicemia of Catfish ...
The /sup 75/Se-selenomethionine pancreas scan and duodenal trypsin levels were compared in 23 normal subjects carefully screened to exclude the principal conditions reported in the literature to be associated with a high incidence of scan abnormalities. The mean trypsin level in the seven subjects who were ...
This study evaluated the application of positive reinforcement training (PRT) as an intervention for abnormal behaviors in singly housed laboratory rhesus macaques at 2 large primate facilities. Training involved basic control behaviors and body-part presentation. The study compared baseline behavioral data on 30 adult males and 33 adult females compared with 3 treatment ...
BackgroundIn the elderly the diagnosis of chronic heart failure is often challenging and the availability of echocardiography can be limited. Plasma levels of NT-proBNP are valuable tools to diagnose patients with heart failure. However, the performance of this biomarker to detect cardiac abnormalities in the very elderly remains unclear. The aims of this ...
Changes in vascular structure that accompany hypertension may contribute to hypertensive end-organ damage. Both the macrovascular and microvascular levels should be considered, as interactions between them are believed to be critically important. Regarding the macrocirculation, the article first reviews basic concepts of vascular biomechanics, such as arterial compliance, ...
Dystonia is characterised by two main pathophysiological abnormalities: reduced excitability of inhibitory systems at many levels of the sensorimotor system, and increased plasticity of neural connections in sensorimotor circuits at a brainstem and spinal level. A surprising finding in two recent papers has been the fact that ...
Positron emission tomography (PET) imaging studies have shown that peak-dose dyskinesia is associated to abnormally high levels of synaptic dopamine (DA) in the caudate-putamen of dyskinetic l-DOPA-treated patients. High striatal extracellular DA levels have also been found in dyskinetic ...
Resistance to insulin metabolic signaling in adipose tissue contributes to the lipid abnormalities in obese, hyperinsulinemic, insulin-resistant patients who develop the cardiorenal syndrome. These same metabolic dyslipidemic abnormalities can be found in conditions of caloric energy restriction with decreased adiposity or normal insulin ...
Legionella pneumophila is a cause of both community- and hospital-acquired pneumonia and might cause high morbidity and mortality. Therefore, early diagnosis and treatment with appropriate antibiotics is crucial. Many clinical and laboratory abnormalities can be observed in the course of Legionella pneumonia. In this study, we aimed to present ...
and measures of heart rate and salivary-cortisol level. The change in CBF induced by the stress task found to correlate with changes in salivary-cortisol level and heart rate caused by undergoing stress data and abnormally high baseline sali- vary cortisol level ( 3 SD), resulting in 23 ...
Friedreich's ataxia is an autosomal recessively inherited disease affecting the nervous system with a high incidence of heart involvement. Abnormalities of lipid metabolism are known to be associated with several progressive ataxic conditions. In this study of 46 Friedreich's ataxia patients, serum lipids, fatty acids and lipoproteins were assayed and ...
Diffuse pulmonary uptake in 67-gallium citrate (67-Ga) scintigraphy occurs in a large number of neoplastic and inflammatory conditions. Discrimination between normal and abnormal 67-Ga uptake over the chest can be difficult and a simple visual method for identifying abnormal studies is described. A series of 39 gallium scintigrams was retrospectively ...
On-site and remote health evaluations were performed on 550 bridge and tunnel workers of the Triborough Bridge and Tunnel Authority in New York City to evaluate the health effects of exposure to high concentrations of automotive emissions. Ambient carbon monoxide concentrations averaged 63 ppm over a 30-day period, with a maximum hourly concentration of 217 ppm in one ...
Vitamin B12 is important for normal nervous system functioning, and deficiencies are associated with various neurological abnormalities. We present a case of an 18-year-old woman who presented with significant neurological sequelae, but only mild hematologic abnormalities and normal vitamin B12 levels. She was found to have a ...
A case of Sj�gren's syndrome with the sicca complex is presented which was associated with persistently low or absent C4 levels, high levels of circulating immune complexes and abnormal reticuloendothelial clearance of damaged or IgG antibody sensitized autologous red blood cells (RBCs). Investigation of normal ...
Alterations in the processing of the amyloid precursor protein (APP) lead to familial Alzheimer's disease (AD). AD patients exhibit increased seizure susceptibility and alterations in their EEGs, which suggests that APP and its metabolites may modulate neuronal networks. Here we demonstrate that transgenic mice overexpressing APP intracellular domain (AICD) and its binding partner Fe65 exhibit ...
The time course of induction of SOS-like stress responses such as enhanced reactivation (ER) and enhanced mutagenesis (EM) has been investigated in UV-C-irradiated skin fibroblasts from a xeroderma pigmentosum (XP) family, using herpes simplex virus type 1 as a probe. Similar ER studies were performed in a Li-Fraumeni syndrome (LFS) family and in a family with a high incidence ...
BACKGROUND AND PURPOSEMR spectroscopic imaging (MRSI) and dynamic susceptibility-contrast MR imaging (DSC-MR imaging) are functional in vivo techniques for assessing tumor metabolism and vasculature characteristics. Because tumor hypoxia is influenced by tortuous, degraded, swollen, and angiogenic tumor vasculature, regions of abnormal perfusion parameters should coexist with ...
While many predators completely consume their prey, others feed only on blood or tissue without killing the prey, sometimes causing ecologically significant levels of injury. We investigated the importance of sublethal predator attacks in driving an emerging issue of conservation importance: missing-limb deformities in amphibians. We combined long-term field data and ...
BACKGROUND: Modified low-density lipoprotein (LDL) immune complexes (IC) have proinflammatory properties and play a role in albuminuria development. METHODS: We measured oxidized LDL (oxLDL) and advanced glycation end-product (AGE)-LDL in IC isolated from sera of Type 1 diabetic subjects followed for 14-20 years and studied their association with abnormal albuminuria. Patients ...
Failure to demonstrate abnormalities on diagnostic tests in patients felt certain to have a disease is all too common, especially when symptoms are mild to moderate. One strategy used in such cases is to perform multiple tests hoping that one will confirm the clinical suspicion. An example of this strategy is found in carpal tunnel syndrome where multiple tests are often used ...
The period immediately preceding the onset of overt psychosis is characterized by a range of symptoms and behaviors including emerging attenuated psychosis, spontaneous movement abnormalities, and a broad decline in role and social functioning. Recent evidence suggests that basal ganglia dysfunction, which is implicated in the development of psychotic symptomatology, may ...
Previous work has shown that the concentration of the essential trace element tin is elevated in several tissues of dialyzed uremic patients. Analysis of 80 postmortem liver samples from controls and nondialyzed uremic and dialyzed uremic patients now shows that nondialyzed uremic patients also have abnormally high tin concentrations, averaging about three ...
An 18 year old man with fibrous dysplasia of bone and several endocrine abnormalities was investigated. Laboratory tests showed high levels of prolactin, TSH and GH and low levels of testosterone and LH. TRH and GnRH showed normal responsiveness of the pituitary in spite of the high hormonal ...
A Facility Radiation and Contamination Monitoring System was installed in the Intermediate and High Level Waste Evaporator Building, Building 2531, to continuously monitor airborne betagamma contamination, beta-gamma background radiation, and steam condensate beta-gamma and gamma radiation. The monitoring instruments and their associated system ...
Subjects with brainstem lesions due to either an infarct or multiple sclerosis (MS) underwent two types of binaural testing (lateralization testing and interaural discrimination) for three types of sounds (clicks and high and low frequency narrow-band noise) with two kinds of interaural differences (level and time). Two major types of ...
Two major classes of lipoproteins, low density and high density, are decreased in the serum of patients with cystic fibrosis; major apoproteins are also decreased. Since essential fatty acids and certain fat-soluble vitamins depend on lipoproteins for transport in the serum, knowledge of lipoprotein levels in cystic fibrosis patients could prove valuable ...
Graphs are presented from the monthly report on the activity levels of {sup 32}P, {sup 76}As, and {sup 65}Zn in the reactor coolant effluent for the following reactors from August, 1958 through November, 1962: B, C, D, DR, F, H, KE, and KW reactors. Alum feed rate data and explanations for abnormally high activity ...
. Crespo et al. (1986) observed intestinal abnormalities in Salmo gairdneri (currently Oncorhynchus mykiss (1993) observed similar results in Oncorhynchus mykiss with liver levels of 60 to 90 lg/g dry weight-exposed Oncorhynchus mykiss with liver levels as high as 4 lg/g dry weight. These few studies on Pb, Cu, and ...
A Faciliiy Radiation and Contamination Alarm System was installed in the High Radiation Level Examination Laboratory, Bui1ding 3525, to continuously monitor beta and gamma radiation and airborne beta-gamma contamination. A monitor was installed in an exhaust duct to determine beta-gamma contamination carried in the exhaust duct. The radiation ...
ObjectiveHigh density lipoprotein (HDL) receptor, scavenger receptor class B, type I (SR-BI), mediated cellular uptake of lipoprotein cholesterol controls HDL structure and plasma HDL and biliary cholesterol levels. In SR-BI knockout (KO) mice, an unusually high plasma unesterified-to-total cholesterol ratio (UC:TC) and ...
Great blue heron hatchlings from colonies in the Strait of Georgia, British Columbia, Canada are being monitored for environmental contaminant exposure and effects by the Canadian Wildlife Service. The contaminants of concern are polychlorinated dibenzodioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), primarily derived from kraft pulp mill effluent. The levels of ...
Background & AimsLiver disease is a major cause of morbidity and mortality among HIV-infected persons. We evaluated the prevalence, etiology, and factors associated with liver dysfunction in patients during the highly active antiretroviral therapy (HAART) era.MethodsWe performed tests for liver function (baseline and after a 6-month follow-up period) in HIV-infected ...
Cerebral infarction associated with ulcerative colitis is particularly rare, but clinically important because of its high morbidity and mortality. The pathogenesis of thrombosis in ulcerative colitis remains unclear even if platelet and coagulation cascade abnormalities, systemic inflammation, and the presence of other well recognized vascular risk factors ...
The molecular and cellular mechanisms underlying nephropathic cystinosis, which exhibits generalized proximal tubular dysfunction and progressive renal failure, remain largely unknown. Renal biopsies from patients with this disorder can reveal abnormally large mitochondria, but the relevance of this and other ultrastructural abnormalities is unclear. We ...
BS>An abnormal serum component was observed 24 hr after administration of a single dose of cadmium to albino rats by intraperitoneal injection, which gradually disappeared from the serum over a period of 9 days. The component was not observed on starch gel electrophoresis following very high or very low dosage, the optimum ...
Although marine organisms are adapted to naturally high concentrations of total dissolved solids (salinity) in their environment, abnormally high or low concentrations of ions can be toxic. Toxicity can result from aberrant levels of a single ion or from shifts of the entire spec...
A 60-year-old man was given a diagnosis of pulmonary and ocular sarcoidosis. His radiological abnormalities and visual disturbance resolved after two years. Ten years later, at age 70, squamous cell carcinoma was detected in the right lower lobe of the lung. Lymphocyte CD4/8 ratio in bronchoalveolar lavage fluid has remained at a high ...
Many individuals with autism tend to focus on details. It has been suggested that this cognitive style may underlie the presence of stereotyped routines, repetitive interests and behaviours, and both relate in some way to sensory abnormalities. Twenty-nine children with diagnosis of high functioning autism or Asperger syndrome completed the Embedded ...
ERIC Educational Resources Information Center
D-dimer can be used to exclude acute pulmonary embolism (PE) for its high negative predictive value (NPV). Also, it is a predictor of recurrent venous thromboembolism (VTE) after anticoagulation withdrawal. The aim of the present study was to assess the predictive value of D-dimer for recurrent VTE when tested at hospital discharge. Plasma D-dimer levels ...
We report a patient with subacute diffuse encephalopathy characterised by rapidly progressive dementia with visual hallucinations, myoclonus and generalised seizures. She was euthyroid but showed high serum levels of thyreoglobulin and thyreoperoxidase antibodies. Hashimoto's encephalopathy was diagnosed. MRI of the brain in the acute phase demonstrated no ...
Testicular biopsies of 84 oligo- or azoospermic males with gonades of nearly normal size and without chromosomal abnormalities were studied by morphometric methods. The mean Johnsen score and the results of the morphometric investigations were plotted against the results of the hormone assays (plasma testosterone, LH, FSH, prolactin). High LH and FSH ...
Although impaired communication is one of the defining criteria in autism, linguistic functioning is highly variable among people with this disorder. Accumulating evidence shows that language impairments in autism are more extensive than commonly assumed and described by formal diagnostic criteria and are apparent at various levels. Phenotypically, most ...
INTRODUCTION:Evaluation of pre- and postoperative serum CEA levels together has seldom been assessed for the prognosis of colorectal cancer (CRC). OBJECTIVE: To concurrently evaluate pre- and postoperative CEA as factors of relapse and survival.METHODS:The study consisted of 114 patients who had undergone surgery from February 2002 to June 2006 for CRC. All patients were ...
Methods for the use of Pin1 as a marker of abnormal cell growth are disclosed. In one embodiment, the method includes detecting a level of Pin1 to stage an abnormal cell growth, such as breast or prostate cancer. In another embodiment, the method includes...
The aim of this study was to analyse the meiotic segregation and DNA fragmentation rates in ejaculated spermatozoa of Tunisian men who presented the macrocephalic sperm head syndrome and to compare the results with those from 20 fertile men with normal semen profiles. Sperm DNA fragmentation was evaluated by the terminal desoxynucleotidyl transferase-mediated deoxyuridine triphosphate biotin ...
Drugs used in disease treatment can cause damage to both malignant and normal tissue. This toxicity limits the maximum therapeutic dose. Drug targeting is of high interest to increase the therapeutic efficacy of the drug without increasing systemic toxicity. Certain tissue abnormalities, disease processes, cancers, and infections are characterized by ...
NASA Astrophysics Data System (ADS)
Single-nucleotide polymorphism array (SNPa) and array-based comparative genomic hybridization (aCGH) are among the most sensitive genomic high-throughput screening techniques used in the exploration of genetic abnormalities in Waldenstr�m's macroglobulinemia (WM). SNP and aCGH allow the identification of copy number abnormalities ...
Garages and auto-repair workshops may be polluted with other heavy metals besides lead. Blood of autoworkers with high lead content was analysed for cadmium, chromium, copper manganese, nickel, ALAD activity and carboxyhaemoglobin level. Cadmium and copper levels in blood of autoworkers were comparable with those of the control ...
Analysis of tsunami height distributions along the coast shows that far tsunami sources give a rather homogeneous and smoothed distributions. On the contrary, we have many examples of abnormal high tsunami run-ups produced by the source near the coast. There are Urup tsunami at 20 October 1963, Nihonkai-Chubu tsunami 26 May 1983, Okushiri tsunami 12 July ...
This study aims at investigating the blood level of Cu, Zn, Se, and Cd in breast cancer patients and the association between such level and the frequency of micronucleated lymphocytes. Fifty stage I breast cancer patients were recruited for this study at the time of diagnosis and before receiving any treatment or surgery. The control group consisted of 150 ...
A modified fibrin-agar overlay assay was used to measure the fibrinolytic activity in human cervical epithelial cells. The fibrinolytic activity results from a cell-associated serine protease that acts as a plasminogen activator. An enzymatic and morphologic comparison of individual normal and abnormal cells reveals that about 50% of the dysplastic and carcinoma in situ cells ...
Background: Persistent Human Papillomavirus (HPV) is an etiologic agent in the development of cervical cancer. Despite the increasingly high prevalence of HPV, people at risk of exposure lack knowledge about the virus, its relationship to cervical cancer, and a realistic perspective regarding HPV consequences. Purpose: To describe knowledge about HPV with particular emphasis ...
... risk for a heart attack is low. Why did the researchers do this particular study? To see ... participants with and without abnormal lipid levels. What did the researchers find? Participants with worse lipid levels ...
Description is given of six body-builders who had been taking Methandrostenolone (up to 20 mg/day in intermittent courses for a year or more). At the time of examination there was no subjective disturbance of sexual function, but testosterone levels were low relative to laboratory standards and luteinizing hormone levels were also reduced - particularly in ...
SYNROC formulations developed for the immobilization of high-level wastes from the civilian power program can be modified to accommodate abnormally high sodium levels in the wastes. The addition of niobium or light rare earth oxides to the inert additives in the SYNROC process results in a wasteform where sodium is ...
Exposure to carbon monoxide compromises function of the cardiovascular system primarily by decreasing oxygen-carrying capacity in the blood and decreasing venous and tissue oxygen tension. In normal individuals, with concentrations of approximately 18 to 20% COHb, there is a reduction in the oxygen consumption during high levels of exercise, a higher than ...
Abnormally high levels of spontaneous and mitomycin C or diepoxybutane induced chromosome breakage were observed in lymphocytes from eight out of nine previously undescribed patients clinically diagnosed as having Fanconi's anaemia. The results suggest that the combination of spontaneous and induced chromosome breakage is a good aid in ...
Based on NCEP/NCAR daily reanalysis data and precipitation data, the circulation background of the extremely heavy rain causing severe floods in Huaihe River valley (HHRV) in 2003 and its relationships to the apparent heating were analyzed. The results showed that the El Nino events with middling intensity during 2002~2003 was the previous background of this extremely heavy rain. The ...
The majority of in-vitro-derived human preimplantation embryos are chromosomally abnormal but whether the same pattern exists in vivo is unknown. This would be impossible to demonstrate in humans. Hence we chose murine embryos to study this difference owing to their ease of manipulation and compared the incidence of mosaicism between in-vivo- and in-vitro-cultured embryos. Two ...
to look for signs of transplant rejection. It may also be done on those with high blood pressure to check differential kidney function. What Abnormal Results Mean Abnormal...
Science.gov Websites
BackgroundInflammation plays an important role in the pathophysiology of both atherosclerosis and type 2 diabetes and some inflammatory markers may also predict the risk of developing type 2 diabetes. The aims of the present study were to assess a potential association between circulating levels of inflammatory markers and hyperglycaemia measured during an acute ST-elevation ...
At variance with protein kinases expressed by oncogenes, CK2 is endowed with constitutive activity under normal conditions, and no CK2 gain-of-function mutants are known. Its amount, however, is abnormally high in malignant cells where it appears to be implicated in many of the cell biology phenomena associated with cancer. These observations can be ...
53 patients suffered from IBS (according to Rome III criteria) were included to the study with solid-phase immune-enzyme detection of the ovalbumin blood level after consumption of egg whites. Patient complaints and quality of life were assessed. The same blood samples were tested for content of the total IgE and specific to food IgE (13 food allergens); specific to food IgG ...
The mute swan (Cygnus olor) is common on British waterways and frequently presents to wildlife hospitals with fishing tackle-related problems. Many of these birds have abnormally high blood lead levels after the ingestion of lead fishing weights. The ingestion of fishing line and tackle is also commonly seen. This case report describes ...
Brain type creatine kinase (BB) isoenzyme was measured using a highly sensitive and specific radioimmunoassay procedure in two schizophrenic populations. The data would indicate that in the schizophrenic populations examined there is insufficient tissue disruption to cause abnormal build-up of brain creatine kinase levels. However the ...
The strongly male-biased sex ratios of probands with polydactyly and of their unaffected sibs suggests that abnormal maternal hormone levels may be involved in this malformation. This suspicion is supported by data relating polydactyly to maternal age and race. High maternal testosterone seems capable of explaining the (admittedly ...
During a screening programme for abnormal haemoglobins in Habana, one case of Hb Porto Alegre was found in 23 000 cases analysed. The ability of this variant to polymerise in vitro and the absence of clinical features in the carriers have been confirmed. These observations are now explained by the findings of high levels of glutathione ...
Given that the need for direct measurement of reactor coolant inventory under operational or abnormal conditions remains unsatisfied, a high-energy gamma-ray detection system is described for ex-vessel monitoring. The system has been modeled to predict re...
Amplification of the HER-2 gene often leads to breast cancer by causing cells to make abnormally high levels of the wild-type HER-2 protein. Evidence now shows that the interaction between HER-2 and HER-3 leads to the constitutive activation of HER-2/HER-...
A reported pesticide odor was investigated at a quarters, Ft. Belvoir, Va. Soil and air samples were taken from under the building and air and wipe samples were taken from within the quarters. Results of sample analyses indicated abnormally high levels of...
Two bison calves were submitted to the Western College of Veterinary Medicine to confirm suspected copper deficiency. In addition to clinical signs, there were pathologic changes in the cartilage and subchondral bone of several joints. Water analysis indicated high levels of sulfate in the drinking water, contributing to a secondary copper ...
A questionnaire was mailed to dentists and dental assistants requesting information about work, health, and reproductive history. Statistical analysis of the data indicated that there were no increased rates of spontaneous abortions or congenital abnormalities in the children of men and women who were exposed to low versus high levels ...
Multiple coagulation studies were carried out in 8 healthy young men at sea level (SL) and after 1, 24 and 48 h at a simulated altitude of 4,400m. Platelet aggregation, as induced by ADP, epinephrine and collagen, was not significantly altered by high alt...
In support of the crystalline silicotitanate (CST) ion exchange project of High-Level Waste (HLW) Process Engineering, heat transfer calculations have been made for a fully-loaded CST column during abnormal and normal operating conditions. The objective of the present work is to compute temperature distributions across the column when there is steady flow ...
DOE Information Bridge
Gait reflects all levels of nervous system function. In psychiatry, gait disturbances reflecting cortical and subcortical dysfunction are often seen. Observing spontaneous gait, sometimes augmented by a few brief tests, can be highly informative. The authors briefly review the neuroanatomy of gait, review gait abnormalities seen in ...
Two siblings displaying macrocrania and multiple skeletal deformities, as well as cardiomegaly, had high levels of serum alkaline phosphatase, and markedly increased urinary hydroxyproline excretion. The radiological findings of chronic familial hyperphosphatasemia, which are typical of a rare bone-remodeling disease, are presented. Scintigraphy disclosed ...
A 26-year-old man developed transient bilateral internuclear ophthalmoplegia with exotropia after cranial irradiation and intrathecal administration of methotrexate for lymphoma. Resolution of the ophthalmoplegia and the decrease in abnormally high levels of cerebrospinal fluid myelin basic protein after discontinuation of intrathecal ...
...treatment of hyperphosphatemia. (a) Hyperphosphatemia is a condition in which an abnormally high plasma level of phosphate occurs in the blood. This condition in not amenable to self-diagnosis or self-treatment. Treatment of this...
...offered for use in the treatment of hyperphosphatemia. (a) Hyperphosphatemia is a condition in which an abnormally high plasma level of phosphate occurs in the blood. This condition in not amenable to self-diagnosis or self-treatment....
Code of Federal Regulations, 2010
Forty-two patients with endogenomorphic depression (ED) and 42 patients with other psychiatric disorders received an overnight dexamethasone test of hypothalamopituitary-adrenal (HPA) suppressibility. Plasma and urinary cortisol measures showed that the ED patients had significantly greater HPA activity before dexamethasone and less complete HPA suppression after dexamethasone. ...
Study Design. To detect drug concentration levels and metabolite using high-performance liquid chromatography.Objectives. To map concentration levels of 3 antituberculous drugs and 2 metabolites in the abnormal osseous tissues around the foci of patients with spinal tuberculosis.Summary of Background Data. ...
Ferula gummosa Boiss. a highly valuable medicinal plant which naturally propagates in very limited areas of the Middle East with specific environmental conditions. The production of Ferula gummosa somatic embryos and the karyological analysis of somatic seedlings were the purpose of this study. High frequency indirect embryogenesis was induced in callus ...
The study was undertaken to evaluate the nature of sensory dysfunction in persons with autism. The cross-sectional study examined auditory, visual, oral, and touch sensory processing, as measured by the Sensory Profile, in 104 persons with a diagnosis of autism, 3-56 years of age, gender-and age-matched to community controls. Persons with autism had abnormal auditory, visual, ...
The study was undertaken to evaluate the nature of sensory dysfunction in persons with autism. The cross-sectional study examined auditory, visual, oral, and touch sensory processing, as measured by the Sensory Profile, in 104 persons with a diagnosis of autism, 3-56 years of age, gender- and age-matched to community controls. Persons with autism had abnormal auditory, visual, ...
The hereditary stomatocytoses are a group of dominantly inherited conditions in which the osmotic stability of the red cell is compromised by abnormally high cation permeability. This report demonstrates the very marked similarities between the cryohydrocytosis form of hereditary stomatocytosis and the common tropical condition south-east Asian ...
Most MRI studies of Alzheimer's disease (AD) and frontotemporal dementia (FTD) have assessed structural, perfusion and diffusion abnormalities separately while ignoring the relationships across imaging modalities. This paper aimed to assess brain gray (GM) and white matter (WM) abnormalities jointly to elucidate differences in abnormal ...
Super-dwarf wheat grown on the Mir space station using the Svet ``Greenhouse'' exhibited morphological, metabolic and reproductive abnormalities compared with Earth-grown wheat. Of prominent importance were the abnormalities associated with reproductive ontogeny and the total absence of seed formation on Mir. Changes in the apical meristem associated with ...
RR variability (HRV), an independent predictor of death following myocardial infarction, may also be related to other features of coronary artery disease. We evaluated its ability to differentiate among sedentary patients with chest pain >/=45 years of age demonstrating either normal or abnormal myocardial perfusion with rest and exercise thallium-210 tomographic imaging. ...
We performed diffusion tensor imaging in two infants with neonatal hypoxic-ischemic encephalopathy. MRI revealed basal ganglia-thalamic lesions in both patients during the neonatal period. Patient 1 had severe neurological sequelae, whereas patient 2 achieved normal development. Conventional MRI at 12 months of age showed abnormal high-intensity areas in ...
Bronchiectasis is an airway disease caused by the dilatation of the bronchial tree, and a bronchovascular pair is formed between a bronchus and a vessel. An abnormal bronchovascular pair is one that has a larger bronchus compared to its accompanying vessel. Typically, bronchi and vessels running perpendicular to the plane of section appear as near-circular rings on computed ...
In health, the pancreatic islet cells work as a network with highly co-ordinated signals over time to balance glycaemia within a narrow range. In type 1 diabetes (T1DM), with autoimmune destruction of the ?-cells, lack of insulin is considered the primary abnormality and is the primary therapy target. However, replacing insulin alone does not achieve ...
Basal and thyroid-releasing hormone-stimulated (200 micrograms/m2) prolactin and thyroid-stimulating hormone (TSH) levels were measured in 31 patients with hypopituitarism (13 isolated growth-hormone deficiencies and 18 multiple pituitary hormone deficiencies). The results were compared with the prolactin response in 76 healthy prepubertal children. Normal prolactin ...
A 61-year-old man presented with a rare case of spontaneous vertebral arteriovenous fistula manifesting as radiculopathy of the left arm. MRI demonstrated an abnormal dilated vascular space on the left ventral aspect of the spinal canal and compression of the spinal cord and subarachnoid space. MRA disclosed a single high-flow vertebral arteriovenous ...
BackgroundData on the prevalence of dyslipidemia and attainment of goal/normal lipid levels in a Swedish population are scarce. The objective of this study is to estimate the prevalence of dyslipidemia and attainment of goal/normal lipid levels in patients treated with lipid modifying therapy (LMT).MethodsThis longitudinal retrospective observational study ...
2,3,7,8-Tetrachlorodibenzo-p-dioxin levels (TCDD) were measured in serum specimens from Seveso, Italy, residents, who were potentially highly exposed to the 1976 explosion, and in controls. The residents were chosen so as to represent those who did and did not develop chloracne. Levels of TCDD as high as 56,000 ...
Preterm infants' physiological indicators, such as heart rate, respiratory rate, and oxygen saturation levels, are routinely monitored by devices that can alert nurses to threatening changes in condition. Most Neonatal Intensive Care Units use standard criteria as alerting algorithms to determine when an alert should be issued, and these standard criteria have been adopted ...
BACKGROUND: Several researchers have reported that Chinese adults may have a greater chronic disease burden than Whites, especially at lower body mass index (BMI) levels. OBJECTIVES: To compare the incidence of lipid abnormalities in Chinese (n=5303), White (n=10,752) and Black (n=3408) middle-aged adults and the effect of BMI on these incidences. METHODS: ...