... Title : ABO ANTIBODIES. I. METHODS FOR QUANTIFICATION OF ABO HEMOLYSINS AND SOLUBLE BLOOD GROUP SUBSTANCES A AND B. ...

A Bioquest ESTEEM module in the Genetics Category. The purpose of this workbook is to compare several methods for calculating allele frequencies for ABO blood groups.

... Galileo Automated Blood Bank System - Add the Reverse ABO Group Assay. ... Product: Galileo Automated Blood Bank System-Add the Reverse ABO Group Assay. ...

Personality trait research has shown associations with many genes, prominently those of the catecholamine metabolism such as dopamine beta hydroxylase (DBH), catechol-O-methyltransferase (COMT), and monoamine oxidase A (MAOA). Because DBH gene is in linkage disequilibrium with ABO gene, there is reason to think that other catecholamine genes using the same substrate as DBH may ...

... albopictus (Diptera: Culicidae) on Human Skin Among ABO Blood Groups, Secretors or Nonsecretors, and ABH AntigensYoshikazu Shiraia,b, ... Japan Abstract We demonstrated in this study that blood group...

In the century since the discovery of the ABO blood groups, numerous associations between ABO groups and disease have been noted. However, the selection pressures defining the ABO distributions remain uncertain. We review published information on Plasmodium falciparum ...

Two technics for the quantitative measurement of ABO hemolysins are described. The first involves the determination of the serum dilution which, in the presence of excess complement, lyses 50% of a standard red cell suspension (QH50). The second measures ...

... of this website will be limited. Search Help? Blood Typing Formal name: ABO Grouping and Rh Typing ... antigens? 1. Do I need to know my blood type? Your blood will always be typed before ...

... India. ABSTRACT We studied the distribution of ABO blood group frequencies of the Galo and Mishing subtribes of ... to investigate the intertribal and temporal allelic variation. Blood groups O and AB s...

... studies on the Panggi are studies of ABO blood group polymorphism (Bhattacharjee 1954; Krithika et al. 2006), cultural ... 1994; Lego 2005). Among the Adi Panggi, ABO blood groups, anthropometric variatio...

... alleles p, q, and r for the ABO blood group system were found to be 0.1295, 0. ... for alleles D and d of the Rh blood group system the allele frequencies were 0.9428 and ... ...

Although a number of studies have demonstrated the influence of ABO blood group on plasma levels of von Willebrand factor (VWF), the nature of this association and its clinical importance is still largely unknown.In this review, the most recent advances in our understanding of the mechanisms by which ABO ...

"Identification error between patient and blood product" is the main cause of ABO-incompatible blood transfusion, but "Phlebotomy error" also has serious consequences. In order to prevent ABO-incompatible transfusion, it is important to establish a management system of blood transfusion in the ...

This study was aimed to establish a genotyping method to detect ABO group gene of fetus from peripheral blood of pregnant women for prenatal diagnosis of hemolytic disease of newborn (HDN) resulting from ABO blood group incompatibility. 4 pairs of primers were designed ...

Contents: Gammelgaard thesis; ABO system--Dunsfore Memorial; Secretion of blood group substances and Lewis system; M N and P systems; Anthropologic and other applications of blood grouping data; Landsteiner centennial; Grethe Hartmann monograph.

Classical works dealing with the possibility of mother-child incompatibility with regard to basic ABO blood groups give contradictory conclusions. Bioreproductive and population-genetic indicators have been studied in a sample of live births and in two pregnancy samples with different "a priori" and "a posteriori" risk assessment. The ...

Classical works dealing with the possibility of mother-child incompatibility with regard to basic ABO blood groups give contradictory conclusions (e.g.--Matsunaga et al. 1962, Thompson et al. 1991). Bioreproductive and population-genetic indicators have been studied in a sample of live births and in two pregnancy samples characterised ...

... States and internationally will enable critical information, such as ABO and Rh blood groups, to be clearly understood by health care professionals transfusing ...

... a specific blood type, characterized by the ABO blood groups and the presence or absence of the Rh factor (Rh positive or Rh negative). Because reactions can occur if a person receives a transfusion of improper blood type, a system of checks and balances (known ...

The aim of this study was to investigate and evaluate the frequency of the antigens classifying the ABO and Rh blood groups in the Greek population. In this study the 3.5% were first generation immigrants with both their parents immigrants from countries of the USSR, while 1.2% had only one immigrant parent, while the other one was ...

that reduction of blood group antibody titer prior to kidney transplantation across the ABO barrier decreased showed that graft survival for kidney transplants across the ABO barrier was 79% at 1�4 years, 75% at 5. Similar success with ABO-incom- patible liver and kidney transplantations were ...

Failure to develop antibodies to nonself A and B blood group antigens is well described after infant ABO-incompatible heart transplantation and suggests that exposure to incompatible ABO antigens early in life may lead to tolerance rather than immunogenicity. If this finding is also true following ...

... December 17, 2004; Accepted: December 20, 2005Keywords: MALARIA, BLOOD GROUPS, ABO, MNSS, DUFFY, BRAZILIAN AMAZON REGION A large ... MNSs (glycophorins A and B), and the Duffy blood group antigen (Daniels...

Interviewee: Matt Ridley DNAi Location:Genome>tour>genome spots>Blood groups Location: chromosome 9 gene name: ABO (galactosyl transferase) The ABO gene codes for an enzyme called galactosyl transferase and determines your blood group. In people with A and B ...

The ABO histo-blood group antigens are best known for their important roles in solid organ and bone marrow transplantation as well as transfusion medicine. Here we report the synthesis of the ABO type III and IV antigens with a 7-octen-1-yl aglycone. Also described is an NMR study of the ABO ...

With the aid of Eldon cards the distribution of the ABO blood groups and of the Rh factor (D) was investigated in different native ethnic groups (Kafirs, Kalash, Chitrali) in the Hindu Kush region of Afghanistan and Pakistan. All studied groups are characterized by a relatively high frequency ...

BackgroundPlacental Protein 13 (PP13), an early biomarker of preeclampsia, is a placenta-specific galectin that binds beta-galactosides, building-blocks of ABO blood-group antigens, possibly affecting its bioavailability in blood.Methods and FindingsWe studied PP13-binding to erythrocytes, maternal blood-group ...

AIM: To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS: Using the University of Pittsburgh�s clinical pancreatic cancer registry, the blood donor database from our local blood bank (Central ...

To examine genetic affinity among Oceanian populations, polymorphisms of exons six and seven of the ABO blood group gene (ABO) were investigated in three populations--Munda town, Paradise village, and Rawaki village--in the New Georgia group of the Solomon Islands. The Munda and Paradise ...

... India. ABSTRACT We studied the distribution of ABO blood groups among three little known subtribes of the Adi ... and Upper Siang districts of Arunachal Pradesh, India. Blood group O was the predominant...

as in humans. This new finding provides us not only an economical and attractive way to synthesize human blood Blood Group B Antigen Tetrasaccharide Wen Yi, Jun Shao, Lizhi Zhu, Mei Li, Mamata Singh, Yuquan Lu, 2004; E-mail: pgwang@chemistry.ohio-state.edu The histo-blood group ...

Anthropologists have assumed that reduced genetic diversity in extant Native Americans is due to a founder effect that occurred during the initial peopling of the Americas. However, low diversity could also be the result of subsequent historical events, such as the population decline following European contact. In this study, we show that autosomal DNA from ancient Native American skeletal remains ...

Noroviruses (NoVs) are a leading cause of viral gastroenteritis in humans. In the present study, the association between NoV susceptibility and the ABO histo-blood group was studied during 2 outbreaks of acute gastroenteritis in military units in Israel caused by genogroup II (GII) NoVs. The findings demonstrate that, unlike for ...

ABO and Rhesus (Rh) blood group antigens are hereditary characters and are useful in population genetic studies, in resolving medico-legal issues and more importantly in compatibility test in blood transfusion practice. Data on frequency distribution of ABO and Rh-D in Niger-Delta region of ...

PurposeTo determine whether corneal graft survival over a five-year follow-up period was affected by ABO blood type compatibility in participants in the Cornea Donor Study undergoing corneal transplantation principally for Fuchs� dystrophy or pseudophakic corneal edema, conditions at low risk for graft rejection.DesignMulti-center prospective, ...

The selection and use of animals with blood group 0 in the process of transplanting pig organs or tissues into humans can positively contribute to the control of acute immune rejection due to differences in blood groups. Exon-specific PCRs for the porcine blood group A ...

OBJECTIVE: The negative effects of cigarette smoking on human reproduction and on birth weight are well documented. On the other hand ABO system, encoding for glycosyltransferases, contributes to biosynthesis of antigens and oligosaccharide structures involved in blastocyst adhesion and intrauterine selection. In this paper we have searched for possible interaction between ...

The distributions of ABO, rhesus, and Lewis blood group antigens were studied in patients with alcoholic cirrhosis, alcoholic pancreatitis, chronic active hepatitis, and primary biliary cirrhosis. There were no differences in frequencies of ABO and rhesus blood group ...

OBJECTIVE: This study evaluated the outcome of liver grafts from ABO incompatible donors, focusing on biliary complications, and compared the results to an ABO compatible control group. Also, the expression of donor ABH antigens in the liver graft was analyzed. SUMMARY BACKGROUND DATA: The outcome of liver transplantation using an ...

The national reference Center for blood groups checked samples of reagents and devices used in France for a definitive verification of pretransfusion ABO tests performed at the patient's bedside, as defined by French health authority regulations. The results of an initial inquiry was published in 1991. The new study shows no ...

Recipients of ABO incompatible allogeneic HSCT present with unusual ABO groups and crossmatch problems accompanied by change of the ABO group from that of the host to the donor. We report on a patient undergoing major ABO incompatible allogeneic HSCT (donor/recipient: A/O) ...

We statistically verify the Hardy Weinberg principle in genetics by investigating the independence of ABO-blood types of married couples. The allelic frequencies derived from the phenotypic frequencies in ethnic groups via the Hardy Weinberg principle are used to define a genetic distance (called the blood distance in this work) ...

... using more complex phenotypic traits such as ABO blood type. Alternatively, the activity can be simplified, and completed ... or a more complex combination such as ABO blood type. More statistical analysi...

Transplantation or transfusion with ABO disparity is a cause for rejection or for severe hemodynamic alterations. ABO groups in pigs are commonly an unknown variable, which has been previously assessed by means of hemagglutination tests or immunohistochemical procedures on tissues. Herein, we have reported a simple method using ...

ABO blood groups and secretor status are important in clinical and forensic medicine and in relation to some diseases. There are geographic and racial differences in their frequencies, but the frequency of secretor status in different ABO blood group systems has not been ...

Chikungunya fever is a viral disease transmitted to humans by the bite of CHIKV virus infected Aedes mosquitoes. During monsoon outbreak of chikungunya fever, we carried out the genetic predisposition to chikungunya in disease affected 100 families by doing blood group (ABO) tests by focusing on individuals who were likely to have a ...

P1 and ABO antigens and bacterial stx genotypes might influence the risk of developing hemolytic uremic syndrome (HUS) after Escherichia coli O157:H7 infections. We determined ABO status and P1 antigen expression in 130 infected and 17 uninfected children, and we determined the stx genotype of the infecting isolate. P1 expression was weakly and directly ...

Historically, forensic and clinical laboratories utilize serological techniques to identify ABO blood types. These techniques rely on the detection of ABO-associated proteins and are sensitive with very accurate results. This laboratory has simplified the identification of ABO types by taking advantage of ...

Why certain individuals progress to severe dengue disease is unknown. In this study, blood groups associated with dengue disease were investigated. ABO phenotypes were identified by use of serum from 399 patients with dengue-virus infection who participated in a cohort study. ABO blood-group ...

Background:ABO incompatibility in maternal�fetal relationship has been shown to cause hemolytic disease of the newborn (HDNB); a survey which is not yet done in this locality.Aim:Frequency of ABO blood group maternal-fetal incompatibility, maternal iso-agglutinins, and immune agglutinins quantitation was carried ...

Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States. Recent reports, including genome-wide association studies and self-reported blood serotype studies, have shown that individuals of European ancestry who carry non-O blood group are at an increased risk of developing pancreatic cancer. Two recent ...

Phenotype studies of ABO blood groups in most Amerindian populations revealed the exclusive presence of group O. Since group O is the result of the absence of glycosyltransferase activity, its molecular bases may be heterogeneous. We carried out ABO ...

Few studies have addressed the incidence of graft-versus-host disease (GVHD) or survival after ABO-incompatible allogeneic peripheral blood stem cell transplantation (PBSCT). We analyzed the clinical outcome of ABO incompatibility after allogeneic PBSCT. A total of 89 consecutive adult patients with hematological diseases including 49 ...

The phenomenon of accommodation in recipients of blood group ABO incompatible kidney transplantation (iKTx), in which grafts survive despite the presence of blood group A or B antigen in the graft and the presence of corresponding antibodies in the recipient's blood, is not ...

Following the hypothesis that Leishmania parasites escape the host defence mechanisms by mimicry of human blood group antigens, conflicting reports have been published. We tested the hypothesis in American cutaneous leishmaniasis, due to L. braziliensis guyanensis, by comparing the distribution of blood groups ...

Rapid user-friendly ABO-Rh blood typing kits (Eldon Home Kit 2511, ABO-Rh Combination Blood Typing Experiment Kit) were evaluated to determine their accuracy when used under simulated military field conditions and after long-term storage at various temperatures and humidities. Rates of positive tests between ...

Six textbooks and two Internet sites show different structures for the A, B, and O(H) antigens of the ABO(H) blood group. However, none of the structures identified as the A, B, and O(H) antigens are correct. The O(H) antigen is a disaccharide, on which the trisaccharide A and B antigens are synthesized. The structures shown in the ...

In sexual assaults against women, one key to identifying the suspect is ABO phenotyping or the typing of other polymorphic markers of the seminal fluid in the victim's vagina. However, ABO phenotyping is frequently unsuccessful, since mixtures of fluids cannot be separated to be subjected to conventional methods for the detection of antibody or antigen ...

The discovery of ABO blood group was a major step in mastering transfusion therapy. Karl Landsteiner (1868-1843) was the author of this discovery. This paper retraces the hard career of this American scientist of Austrian origin, and describes the circumstances that led his research to the discoveries, which were turning points in the ...

of BabA, the H. pylori ABO Blood Group Antigen Binding Adhesin Marina Aspholm-Hurtig,1 Giedrius Dailide,2 * Thomas Bore�n1,18 * Adherence by Helicobacter pylori increases the risk of gastric disease. Here, we by specialist binding in blood group O�dominant human populations. The gastric ...

Automated microplate blood-grouping systems rely on a pair of thresholds to determine whether reactions are positive or negative. The determination of these thresholds is a critical step in the quality control process for automated microplate blood grouping. A simple method has been developed for automatically setting these thresholds. ...

2,140 pregnant Sudanese women attending the antenatal clinic in Omdurman Maternity Hospital during the period November 1975 to December 1976 had ABO and Rh typing performed. Their sera were also screened by a modified papain enzyme technique for the presence of atypical antibodies. The rate of Rhesus immunization, the frequency distribution of blood ...

In addition to the issues concerning blood transfusions in general, special considerations apply to transfusing neonates. Young infants' plasma may contain maternal antibodies to ABO blood group antigens instead of the naturally occurring anti-ABO antibodies normally present in older patients. ...

Gene expression is driven by promoters, enhancers, silencers, and other cis-regulatory elements upstream and downstream of the gene. Previous studies of the regulation of human ABO gene transcription have focused mainly on the 5' region, including the core promoter and the region proximal to it. However, as the involvement of the 3' flanking region in transcriptional ...

BackgroundPrevious studies have examined the association between ABO blood group and the risk of some malignancies. However, no prospective cohort study to date has examined the association between ABO blood group and the risk of skin cancer.Methodology/Principal ...

BackgroundElevated serum soluble E-selectin levels have been associated with a number of diseases. Although E-selectin levels are heritable, little is known about the specific genetic factors involved. E-selectin levels have been associated with the ABO blood group phenotype.Methods and ResultsWe performed a high-resolution genome-wide ...

Intravenous immunoglobulin (IVIG) has been found to decrease hemolysis in neonatal jaundice due to blood group incompatibility, but a consensus on its usage has not been reached. We conducted a study to compare single versus multiple dose of IVIG in combination with light emitting diode (LED) phototherapy in patients with neonatal jaundice secondary to ...

The technique can be useful in detecting weak subgroups of the ABO blood group system. However, it is not possible to classify these weak subgroups into specific categories, e.g., A3, Am, or Ax, using this technique, since they do not segregate into well ...

Percentage distributions of nine genetic markers, including ABO blood type, secretor ability, haptoglobin type, transferrin type, and group specific component type, are presented and discussed by age, sex, race, geographic region, family income and parent...

Acute hemolytic anemia is one of the side effects associated with cyclosporin and tacrolimus therapy, and three mechanisms have been described to account for hemolytic anemia in patients receiving these drugs: drug induced hemolysis, autoimmune hemolysis and alloimmune hemolysis resulting from donor lymphocytes derived from the allograft (passenger lymphocyte syndrome). We report four cases of ...

Blood genotyping was performed in three patients with ABO-group transformation hematological disorders. Serological examinations revealed the following A-subtype transformations: case 1 was AML with A3B; case 2 was RAEB in transformation with A3; case 3 was AML with Alnt. Polymerase chain reaction (PCR) followed by restriction fragment length polymorphism ...

SummaryBackgroundValidations of routinely used serological typing methods require intense performance evaluations typically including large numbers of samples before routine application. However, such evaluations could be improved considering information about the frequency of standard blood groups and their variants.MethodsUsing RHD and ...

BackgroundPersistent anti-donor isoagglutinins after major ABO blood group incompatible hematopoietic stem cell transplantation may cause delayed red blood cell engraftment and post-transplant pure red cell aplasia.Design and MethodsWe investigated the effect of pretransplant anti-donor isoagglutinin reduction by ...

The blood type of a person is a combination of ABO blood type and Rh factor. ... A child of parents with blood types A+ and B+ could have any blood type. ...

Background: Generalised immune stimulation may follow vaccination causing increased antibody titres of nonvaccine-related antibodies or bystander antibodies, including those to human leukocyte antigens (HLA) and ABO blood group antigens. HLA antibodies may lead to transfusion-related acute lung injury. High-titre ...

, is the most clinically important in transfusion medicine. The Rh antigens are carried by two red blood cell cell membrane, where they consti- tute the second most important group of antigens used in transfusion medicine after the ABO group. Rh proteins are related to the ammo- nium transport (Amt) protein family

Depending on the ABO blood group, gonorrhea may affect the titers of isohemagglutinins compared with those of uninfected controls. The isohemagglutinin titers in group O patients were significantly increased (P less than 0.001) against erythrocytes A, B, and AB. In group A patients, only the ...

There is growing epidemiological and molecular evidence that ABO blood group affects host susceptibility to severe Plasmodium falciparum infection. The high frequency of common ABO alleles means that even modest differences in susceptibility could have a significant impact on the health of people living in malaria ...

There is growing epidemiological and molecular evidence that ABO blood group affects host susceptibility to severe Plasmodium falciparum infection. The high frequency of common ABO alleles means that even modest differences in susceptibility could have a significant impact on the health of people living in malaria ...

The Phayengs and Khurkhuls are sections of the Meiteis, the largest community in Manipur, India. Racially they are Mongoloids, and marry mostly among themselves. The present study reveals the frequencies of ABO blood groups as A1 (36.54%), B (28.85%), O (25.96%) and A1B (8.65%) in the Phayengs (n = 124) and A1 (39.84%), B (21.14%), O ...

A survey has been made to assess the evidential value of tests carried out on 660 casework penile swabs. Most were from suspects in sexual assaults and were examined to see if the donor had had recent anal, oral or vaginal intercourse. The swabs were tested for one or more of the following: blood, faeces, saliva, vaginal secretions, semen. Blood was seldom ...

Electronic crossmatching (E-XM) is used to detect ABO incompatibility. In developing countries, as many of the donations are from first-time donors, it is difficult to guarantee the accuracy of the ABO/Rh label on these units to use them for E-XM. This problem was overcome with a new software 'hemosoft', using donors' blood ...

P-selectin and intercellular adhesion molecule-1 (ICAM-1) participate in inflammatory processes by promoting adhesion of leukocytes to vascular wall endothelium. Their soluble levels have been associated with adverse cardiovascular events. To identify loci affecting soluble levels of P-selectin (sP-selectin) and ICAM-1 (sICAM-1), we performed a genome-wide association study in a sample of 4115 ...

A recent genome-wide association study (PanScan) identified significant associations at the ABO gene locus with pancreatic cancer risk; however, the mechanisms underlying these associations and the influence of specific ABO genotypes remain unknown. We determined ABO genotypes (OO, AO, AA, AB, BO, BB) in 1534 cases and 1583 controls ...

This paper reports a homicidal case in which the absorption-elution technique using nitrocellulose beads as immunoadsorbents was successfully applied to ABO grouping from highly-diluted blood. A 21-year-old man was found dead in bed while staying in a hotel. He had multiple wounds over the entire body. By autopsy the cause of death was ...

AbstractThe ABO histo-blood group system is the most important antigen system in transplantation medicine, yet no small animal model of the ABO system exists. To determine the feasibility of developing a murine model, we previously subcloned the human ?-1,2-fucosyltransferase (H-transferase, EC 2.4.1.69) cDNA and ...

Determination of predicted blood group phenotype by determination of genotype has been performed since the 1990s. This evolved due to the rapid accrual of information surrounding the molecular basis of blood group antigen expression, which started in 1990 with ABO and RH systems and has now ...

and induction of mutations among descendants of exposed animals. Genetic properties of each individual, such as ABO blood type and hair color in humans, are ...

Objective/Aim: The aim of this study is to describe the distribution of the platelet blood group A antigenicity in Euro-Brazilians (EUBs) and Afro-Brazilians (AFBs).Background: A small but significant proportion of individuals express high levels of A or B antigen on their platelets corresponding to the erythrocyte ABO ...

Sera from 1036 donors at the Hemotherapy Service of the General Hospital "Luis D�az Soto" were evaluated for IgG anti-Toxoplasma gondii antibodies. No significant difference was found among sexes. The presence of T. gondii antibodies were distributed in eight age categories; a minor and a major presence of specific IgG for the young and old age groups, respectively was ...

Ludwik Hirszfeld, together with his wife Hanka, was the first to study the blood groups in large numbers of subjects (soldiers) during World War I at the Macedonian front. They found significant differences in the distribution of the ABO blood groups, that is, type A was more common in soldiers ...

Studies of ABO, Rh, MN, rho, Lewis blood groups in coal miners suffering from anthracosilicosis and in reference healthy individuals proved that MM phenotypes are predisposed to anthracosilicosis and MN phenotypes could be resistant to the disease. These results could be valuable for prevention of this occupational disease among coal ...

Metabolic beta adrenergic responses to terbutaline are significantly reduced in asthma compared to chronic bronchitics, in whom responses are normal. Responses become partially tolerant during maintenance oral terbutaline therapy, some requiring two weeks...

There is a growing number of lipoprotein markers recognized by immunological, electrophoretic, and other biochemical methods, and a beginning has been made on studying their modes of inheritance and linkage relations. Suggestive but inconclusive evidence of a relation between the cerumen polymorphism and arteriosclerosis has been published. Associations of the ABO ...

A pair of discordant twins, one of whom had Noonan syndrome, is reported. Most of the cardinal signs of Noonan syndrome were demonstrated by the affected twin. The etiology of the syndrome is briefly reviewed. The dizygosity of the twins was proved by ABO blood grouping and mixed lymphocyte reaction. The findings are interpreted as ...

Blood group O and the cysteine allele of the Y/C1584 change in von Willebrand factor (VWF) are enriched in type 1 VWD, but neither causes disease. We investigated the effect of C1584, alone and in combination with the ABO blood group, on the level and properties of plasma VWF. A cohort of 5052 ...

Modified red blood cell survival studies with use of 51Cr were performed in three groups of subjects. Group 1 consisted of normal subjects who were given labeled autologous blood, group 2 were subjects in need of blood transfusions and given labeled ABO ...

Genotyping is useful to predict the expression of those RBC antigens for which antisera are difficult to obtain, to determine the probable phenotype of highly transfused patients, and can be used to test stored DNA when a blood sample is not available. This study assessed a sequence-specific primer (SSP)-based genotyping system for blood ...

During the 1950's and 60's as new blood group systems were identified, antigen distribution studies were performed in Europe and North America among Caucasians and American Blacks. However, to date only limited studies have been performed in Africa and Asia. Because of lack of knowledge of the antigen distribution of most other than ...

This study was carried out to investigate the relationship between juvenile and non-juvenile peridontitis (JP, non-JP), ABO blood groups and haemoglobin type. The heamoglobin electrophoresis was determined by routine technique using cellulose acetate paper and tris buffer at pH 8.5. Tile blood ...

AimTo assess the association between ABO blood group genotypes and genetic risk factors for thrombosis (FV Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations) in the Croatian population and to determine whether genetic predisposition to thrombotic risk is higher in non-OO blood ...

Human chimerism is the presence of ?2 cell populations in one person that contain genetic material from more than one zygote. Chimerism may be either acquired by transfusion or transplantation of donor cells, or congenital arising from embryo fusion or dizygotic twin-twin transfusion. We encountered a 4-year-old boy with developmental hip dysplasia whose preoperative (serologic) ...

ABO allo-immunization is the most frequent hemolytic disease of the newborn and ABO incompatibility is present in 15-25 % of pregnancies. True ABO alloimmunization occurs in approximately one out of 150 births. Intensity is generally lower than in RhD allo-immunization. We report on three cases showing that ABO ...

Living donor kidney transplantation is the preferred therapeutic option for patients with end stage renal disease because it provides a superior immunological compatibility, it lessens the preservation-mediated graft injury and it shortens waiting time on dialysis. Unfortunately, about 30-35% of potential living kidney donors are rejected because of incompatible immunological barriers such as ...

Specific B-cell tolerance towards donor blood group antigens develops in infants after ABO-incompatible heart transplantation, while their immune response towards protein antigens such as HLA has not been investigated. We assessed de novo HLA antibodies in122 patients after pediatric thoracic transplantation (28 ...

Chimerism in humans is a rare phenomenon often initially identified in the resolution of an ABO blood type discrepancy. We report a dispermic chimera who presented with mixed field in his B antigen typing that might have been mistaken for the B₃ subtype. The propositus is a healthy Korean male blood donor. ...

Human A, B, and O blood type is determined by the presence or absence of distinct carbohydrate structures on red blood cells. Type O individuals have ?-fucose(1?2)galactose disaccharides [O(H) structures] on their cell surfaces while in type A or B individuals, the O antigen is capped by the addition of an ?- N -acetylgalactosamine or ?-galactose residue, ...

BACKGROUND: Identification of blood group antigen frequencies in a population has various benefits in transfusion medicine. Most data in the literature include frequencies of these antigens in European and American countries. In this study for the first time we have reported frequencies of these antigens in the northeast of Iran. MATERIALS AND METHODS: ...

An attempt has been made to interpret the quite rare distribution pattern of ABO blood group genes (p > 0.5000, q < 0.1000 and r < 0.5000) among the Prasun Kafirs and the Kalsh of the central Hindu Kush from the point of view of population genetics and ethnohistory. If we consider the different age groups ...

A one-step Du test, developed for use in automated microplate systems, uses anti-D with 0.6 percent dextran to potentiate the reaction. Because the washing and reagent-adding steps of the antiglobulin test are not required, the Du test can be performed in the same microplate as the ABO/Rh test. A set of reactions prepared with this technique was visually interpreted and also ...

Background: Fetal Growth restriction (FGR) is associated with thrombosis of the placenta and an increased risk of subsequent vascular disease in the mother and fetus. The products of interactions between ABO(H), Lewis and Secretor genes are also associated with thrombosis and vascular disease risk. Objectives/Methods: A prospective case-control study of mothers with a severe ...

Blood groups of humans and great apes have long been considered similar, although they are not interchangeable between species. In this study, human monoclonal antibody technology was used to assign human ABO blood groups to whole blood samples from great apes housed in ...

Lysates of heads, hind- and midguts of male and female Phlebotomus papatasi were found to contain lectins or lectin-like molecules capable of agglutinating human red blood cell types of the ABO(H) system and promastigotes of Leishmania aethiopica, L. major and L. donovani but not L. hertigi hertigi promastigotes or Crithidia fasciculata choanomastigotes. ...

The ability of glycoproteins from pig intestinal brush border membranes (BBM) to bind cholera toxin (CT) or heat-labile toxins from strains of Escherichia coli isolated from human (LTh) or pig (LTp) intestines was studied. Glycoproteins capable of binding the toxins are also recognized by antibodies or lectins specific for ABO(H) blood ...

BackgroundIn malarious areas of the world, a higher proportion of the population has blood group O than in non-malarious areas. This is probably due to a survival advantage conferred either by an attenuating effect on the course of or reduction in the risk of infection by plasmodial parasites. Here, the association between ABO ...

One thousand two hundred and fifty-one subjects, who were exposed to the atomic bomb in Hiroshima, were examined for the presence of achlorhydria as measured by the Squibb tubeless gastric analysis. The proportion with achlorhydria was analyzed as to age, sex, blood group, and exposure to atomic- bomb radiation. It was found that Japanese ...

Although hemagglutination serves the immunohematology reference laboratory well, when used alone, it has limited capability to resolve complex problems. This overview discusses how molecular approaches can be used in the immunohematology reference laboratory. In order to apply molecular approaches to immunohematology, knowledge of genes, DNA-based methods, and the molecular bases of ...

Although hemagglutination serves the immunohematology reference laboratory well, when used alone, it has limited capability to resolve complex problems. This overview discusses how molecular approaches can be used in the immunohematology reference laboratory. In order to apply molecular approaches to immunohematology, knowledge of genes, DNA-based methods, and the molecular bases of ...

Since platelets possess A and B antigen, mismatched ABO platelets could, theoretically, become activated or hypofunctional by exposure to anti-A or anti-B antibodies found in transfused or recipient plasma. Following normal baseline platelet aggregation to adenosine diphosphate (ADP), platelets from normal donors of different blood types were incubated at ...

Little is known about the role of association between ABO blood type and risk of pancreatic cancer develops through effects on hepatitis B viral (HBV) infection. This study aimed to determine whether joint ABO blood type and HBV infection could increase the risk for pancreatic cancer. A total of 645 patients with ...

For centuries, man has been trying to figure out how to revive sick and traumatized individuals using fluids of various types, even from animals. In the 17th century, it was determined that blood was the best fluid to use and, in the early 1900s, after the discovery of the ABO blood groups, human ...

We conducted a two-stage genome-wide association study (GWAS) of pancreatic cancer, a cancer with one of the poorest survival rates worldwide. Initially, we genotyped 558,542 single nucleotide polymorphisms in 1,896 incident cases and 1,939 controls drawn from twelve prospective cohorts plus one hospital-based case-control study. In a combined analysis adjusted for study, sex, ancestry and five ...

Thrombotic microangiopathy (TMA) has rarely been reported in the setting of liver transplantation. Herein we have reported a successful case of TMA after ABO-incompatible living donor liver transplantation (LDLT) treated with plasma exchange and high-dose intravenous gamma-globulin infusion. A 50-year-old woman was diagnosed with hepatitis C virus-related cirrhosis. We ...

In order to determine genetic differences between 50 examinees with ischemic cerebrovascular accident (iCVA) and those of comparative group, we have chosen 1883 persons from phenotypic healthy population divided into 5 different subgroups. The purpose of our investigation was exploring hereditary characteristics of antigenes linked to erythrocyte membrane. The highest ...

BACKGROUND: It has been postulated that blood group O subjects may be partially protected against thrombotic thrombocytopenic purpura (TTP) because they have lower plasma levels of von Willebrand factor. STUDY DESIGN AND METHODS: The Oklahoma TTP Registry enrolled 301 consecutive patients from November 13, 1995 (when systematic ADAMTS13 measurements ...

Centenarians are the best example of extreme human longevity, and they represent a selected population in which the appearance of major age-related diseases, such as cancer, and cardiovascular diseases among others, has been consistently delayed or escaped. The study of the long-lived individual genetic profile has the purpose to possibly identify the genes and the allelic variations influencing ...

The fucosylated ABH antigens, which constitute the molecular basis for the ABO blood group system, are also expressed in salivary secretions and gastrointestinal epithelia in individuals of positive secretor status; however, the biological function of the ABO blood group ...

BackgroundThe possibility that allogeneic hematopoietic stem cell transplantation performed across the ABO blood group-barrier is associated with an increase of graft-versus-host disease, in particular endothelial damage, has not been elucidated so far. For this reason, we investigated the level of endothelial cell chimerism after ...

Chikungunya virus (CHIKV) an emerging arboviral infection of public health concern belongs to the genus Alphavirus, family Togaviridae. Blood group antigens are generally known to act as receptors for various etiological agents. The studies defining the relationship between blood groups and CHIKV is limited and ...

... The sites included in the study were: � University of Virginia - Charlottesville, VA � Heartland Blood Center - Aurora, IL � Univ. ...

... biology courses including: introductory biology and immunology at college and ... students. Through manipulation of the model cells, students practice ... ...

ABO-incompatible transfusions and transfusion-related lung injury are today the leading transfusion-related causes of death in the developed world. Since anti-A and anti-B antibodies in plasma can give rise to serious, even fatal, transfusion reactions,ABO-identical/compatible plasma is indicated, but presents a logistical challenge and a risk for ...

Erythrocytic group antigens represent a genetically stably determined trait. Investigation of antigens of the said system in different regions is of the greatest importance in terms of both the creation of demographic data of the region as well as practical medicine, especially for transplantology and transfusiology. The peripheral or venous blood of 232 ...

Blood groups according to ABO and Rh systems were tested in 137 ulcer patients as well as the secretory state. The titre of blood group ABH antigens was determined in the same patients, secreted in saliva and gastric juice. The results are compared with those obtained from the examination of a ...

ABO genotyping is often performed to identify the blood type of decomposed samples, which is difficult to be determined by a serological test. In this study, we developed a simple method for ABO genotyping using a DNA chip. In this method, polymerase chain reaction-amplified and fluorescent-labeled fragments in the ...

Results of HLA-A, B and C typing as well as haplotype frequencies in the Nahuas, who are the predominant Indian group in Mexico are presented. ABO and Rh blood groups show the genetic homogeneity of this population, since all of them were group O and Rh+. The most frequent antigens and ...

Patient safety in transplantation depends on accurate testing, transcription and transmission of the ABO types of the donor and recipient. Similar to 'near-miss' transfusion labeling errors, three cases of mislabeled ABO types on deceased donor kidney containers were recognized through a pretransplant verification process. Six steps to confirming the organ ...

BACKGROUND: Kodecytes bearing synthetic blood group A and B antigens are increasingly being used in transfusion laboratories as serologic mimics of red blood cell (RBC) A(weak) and B(weak) subtypes. The aim of this study was to compare the flow cytometry profile of kodecytes with native ABO subgroups. STUDY DESIGN ...

An unusual blood group inheritance, that is, a phenotype O child from AB X O parents, was found in a Japanese family. Since two other children from the parents are blood type B, this is not a case of Cis-AB inheritance. The mother is not blood A/B chimera, and normal levels of blood ...

A blood group substance (BGS), a protein with ABH antigenic activity, was isolated from human seminal plasma and designated as p 84 (Sato, 1995). We have developed a method for determining the ABO blood type of semen by performing a sandwich enzyme-linked immunosorbent assay (ELISA) in which p 84 is captured with ...

Purpose of reviewThis review summarizes recent advances in our understanding of the interaction between malaria parasites and blood group antigens and discusses how the knowledge gleaned can be used to target the development of new antimalarial treatments and vaccines.Recent findingsStudies of the interaction between Plasmodium vivax and the Duffy antigen ...

PurposeThe number of patients waiting for kidney transplantation is incessantly increasing, but the number of cadaveric kidney transplantations or ABO-compatible donors is so insufficient that ABO-incompatible kidney transplantation is being performed as an alternative. There are overseas studies and research showing that the 5-year survival rate and ...

Blood group A was found to be associated with gastric cancer in the 1950s. Strikingly, for peptic ulcers an increased risk has been shown for blood group O. However, previous investigations have generally been poorly conducted and have failed to take a unifying approach to these observations. Using the Scandinavian ...

Aqueous extracts of human neoplastic and adjacent normal colonic mucosa were investigated for hemagglutination inhibition of both the anti-A serum and the Dolichos biflorus lectin. The anti-A antiserum was inhibited by the extracts from neoplastic tissues to a much higher extent than by that from normal mucosa; the inhibition was strictly dependent on the blood ...

ABO typing is the first test done on blood that is to be used for transfusion. A person must receive ABO-matched blood, as ABO incompatibility is the major cause of fatal transfusion reactions. Until now, this blood typing has been done manually, and there is therefore a ...

The system described here can distinguish between single and agglutinated erythrocytes by use of a non-flow fiber optic fluorometer. The method is capable of detecting cell-surface antigens and antibodies to cell-surface antigens present in blood. Significant features include high-efficiency fluorescent dyes that intercalate into cell membranes, a stretching membrane for ...

Limitations of polyacrylamide gel or agarose gel electrophoretic methods in genotyping research affect the interpreting of detection results. In order to develop a simple and reliable method for appraising results of ABO genotyping detection, the microfluidic chip analysis system was established by using microfluidic chip to replace the gel electrophoresis and combining with ...

The aim of this study was the detection of helicobacter pylori (HP) infection and estimation of this infection relationship with age, gender, blood groups and Rhesus factor, as well as the assessment of the accuracy of the method. A total of 227 patients with gastritis were examined. Blood ABO ...

Comparative analysis of allelic variation of a gene sheds light on the pattern and process of its diversification at the population level. Gene families for which a large number of allelic forms have been verified by sequencing provide a useful resource for such studies. In this regard, human blood group-encoding genes are unique in that differences of ...

Incompatible blood group antigens are highly immunogenic and can cause graft rejections. Focusing on distinct carbohydrate- and protein-based membrane structures, defined by blood group antigens, we investigated human bone marrow-derived mesenchymal stem cells (MSCs) cultured in human serum. The presence of H ...

BACKGROUND.: A novel immunosuppression protocol using rituximab and plasma exchange treatment was developed for ABO-incompatible living donor liver transplantation (ABO-I LDLT). The aim of this study was to investigate the kinetics of anti-blood type isoagglutinin titers and the number of blood B lymphocytes in ...

A plug-based microfluidic approach was used to perform multiple agglutination assays in parallel without cross-contamination and using only microliter volumes of blood. To perform agglutination assays on-chip, a microfluidic device was designed to combine aqueous streams of antibody, buffer, and red blood cells (RBCs) to form droplets 30�40 nL in volume ...

...The specialty of immunohematology includes four subspecialties for the purposes of proficiency testing: ABO group and D (Rho) typing; unexpected antibody detection; compatibility testing; and antibody...

Passenger lymphocyte syndrome (PLS) is a well-recognized complication that may follow a hematopoietic progenitor cell or solid-organ transplant. Typically, the syndrome presents as acute hemolysis of the recipient's RBCs, which have become serologically incompatible with blood group antibodies formed by passively transfused donor-origin B lymphocytes. Most ...

Cell surface carbohydrate antigens show changes in relation to differentiation, maturation and malignant transformation. The expression of type 2 chain ABH carbohydrate structures of the ABO histo-blood group system was investigated in 28 pleomorphic adenomas (PA) and normal parotid glands in order to study possible changes in the ...

Data are presented on polymorphic genetic markers of 84 Welsh gypsies, members of an inbred population characterised by a high incidence of phenylketonuria and other recessively inherited diseases. Sixteen polymorphic loci were studied: the ABO blood group distribution was comparable to that of the surrounding population, the B gene ...

ABO-incompatible living-donor lobar lung transplantation was performed in a 10-year-old boy with bronchiolitis obliterans (BO) after bone marrow transplantation (BMT) for recurrent acute myeloid leukemia (AML). His blood type had changed from AB to O since he underwent BMT and he had no anti-A/B antibody, and received type B and AB donor lobar lungs. To ...

Successful ABO-mismatched renal transplantation (RT) (blood group A2 donor to blood group B or O recipient) has occurred in adults in the setting of a low titer (< or =4) natural isoagglutinin (anti-A) level in the recipient of the mismatched organ. Similar experiences have rarely occurred ...

BackgroundSubjects with non-O ABO blood group alleles have increased risk of pancreatic cancer. Glycosyltransferase activity is greater for the A₁ versus A₂ variant, while O01 and O02 variants are nonfunctioning. We hypothesized: (1) A¹ allele would confer greater ...

Norovirus is a major cause of acute gastroenteritis in humans. A norovirus outbreak occurred in Ohio in January 2010. Stool and saliva samples were obtained from six infected individuals. The full-length genomes of two representative strains (HS206 and HS210) were characterized. They belonged to GII.12 in the capsid but GII.g in the RNA polymerase region. Interestingly, an immunocompetent ...

BackgroundThe virulence of Plasmodium falciparum is associated with the capacity of the infected red blood cell (iRBC) to adhere to uninfected RBCs, a process known as rosetting, which has been linked to the occurrence of severe malaria. The present study was carried out in three Ethiopian malaria endemic localities to investigate the relationship between ...

Allele frequencies are reported for 19 blood group, red cell enzyme, and serum protein loci (ABO, Rh, MN, Hb-A, LDH-A, LDH-B, SOD, PGM-1, PGM-2, 6PGD, GPT, ESD, ADA, ACP, PGK, MDH, Alb, Hp, and Tf) determined from 310 blood samples collected among the Gainj, a small population of tribal horticulturalists from ...

An immunological and immunogenetic investigation of coal worker's pneumoconiosis (CWP) was conducted. Four geographic regions of study were established, depending on the type of coal mined in the region. Blood samples were taken from 358 workers with no disease, simple CWP, or complicated CWP. Samples were tested for histocompatability, blood ...

Phenotype distributions of some genetic polymorphisms are reported in a sample of 721 diabetics and 515 non-diabetic, non-blood donor controls. Reference is also made, in the case of the ABO and Rhesus systems, to previously published results for blood donors resident in the Durham area. Non-insulin-taking diabetics show an increased ...

We report a case of an epidermolysis bullosa acquisita (EBA) patient with a unique immunofluorescence pattern. The patient had pruritic erythematous plaques and tense blisters. Histopathological examination showed a subepidermal blister without acantholysis. Salt-split direct immunofluorescence demonstrated clear linear IgG and C3 deposition along the dermal side of the basement membrane zone; ...

Removal of Anti-A/B antibodies prior to ABO-incompatible transplantation can prevent hyperacute organ rejection. We are developing a specific antibody filter (SAF) device to selectively remove ABO blood group antibodies from the whole blood by utilizing immunoaffinity adsorption. The device ...

The ABO blood group system has been implicated in susceptibility to cholera or in explaining variability in the immune response to a cholera vaccine. O blood group individuals were found to be more susceptible to cholera and elicited lower vibriocidal antibody response to cholera toxin B ...

Blood groups ABO, MN, Rhesus, P, and Lewis, salivary ABH secretion, and at the HLA DQ alpha locus were studied in 65 Caucasian children of both sexes diagnosed as having acute febrile urinary tract infection in the 1st year of life, as well as in 60 Caucasian control children. No differences were observed between patients and controls. ...

The group participated actively with nine research projects in the 6-year Combustion and Gasification Research Programme LIEKKI 2, which concluded its fourth year of activity. The group also continued to be the coordination organization of this national r...

BACKGROUND: We analyzed neonatal factors that could affect hematopoietic variables of cord blood (CB) donated from Korean neonates. STUDY DESIGN AND METHODS: The numbers of total nucleated cells (TNCs), CD34+ cells, and CD34+ cells/TNCs of CB in neonates were compared according to sex, gestational age, birth weight, birth weight centile for gestational age, and ...

We have used the gene-centric Illumina HumanCVD BeadChip to identify common genetic determinants of Von Willebrand factor (vWF) levels in healthy men and women. The Whitehall II (WHII) study (n= 5592) and the British Women's Heart and Health Study (BWHHS) (n= 3445) were genotyped using the HumanCVD BeadChip. Replication was conducted in the British Regional Heart Study (n= 3897) and 1958 Birth ...

Removal of blood group anti-A and anti-B antibodies can prevent hyperacute organ rejection in ABO-incompatible transplantation. We are developing an extracorporeal-specific antibody filter (SAF) as an immunoadsorption device for direct removal of ABO blood group antibodies ...

A simple and reliable technique for removal of ABO incompatible marrow red cells is described. This method requires a blood cell processor and third party red cells are used as a shelf. Using this technique, nine children age 0.5-11.5 years received allogeneic bone marrow transplantation from ABO incompatible donors. A median of 4.8 ml ...

Paternity is based on biological analyzes that have drastically developed during the past 20 years. According to scientific developments, paternity testing was based on red blood groups studies, the analysis of red cell enzymes and plasma proteins polymorphisms, the typing of the HLA antigens, and the DNA polymorphism in its various forms. This study aims ...

Research on genetic markers in the fields of forensic medicine and human genetics did not begin in earnest until 1968. Study of an extended family in Wakayama Prefecture resulted in the discovery of the variant Bm type in the ABO blood group system. This family of nearly 40 members composed of Group A, B, O and AB ...

Multivariate analysis was performed to determine the independent factors affecting the risk of acute GVHD (aGVHD) grades II to IV and extensive chronic GVHD (cGVHD) and the rate of survival in 481 recipients of T cell-depleted (TCD) marrow allografts who received transplants at a single center between 1991 and 2000. All patients received grafts partially depleted of CD3+ T cells by ...

A molecular characterization of alleles O1, O1variant (O1v), and the mutation G542A of the ABO blood group was performed in two Amerindian populations of Chile, the Aymara (n = 84) and the Huilliche (n = 75). In addition, a sample of 82 individuals of Santiago belonging to the mixed Chilean population was typed for comparative ...

... No. % No. % No. % TRALI 29 47% 35 56% 34* 65% 98 55% HTR (non-ABO) 16 26% 9 14% 2 4% 27 15% Microbial ...

The encapsulation of live cells with polymeric coat-ings is a versatile approach to modulate or control the response cells to their environment. The layer-by-layer (LbL) self-assembly of nonimmunogenic polyelectrolytes is employed here to attenuate or suppress the binding of antibodies to live red blood cells (RBCs) and, consequently, decrease their inherent immunogenicity ...

It is well known that Phaseolus species contains lectins of various specificities 1-4. Runner bean5 and different varieties of Ph.coccineus described by Ochoa et al6, are not specific to human blood groups. They react indistinctly with erythrocytes of the ABO system. However the lectin of Ph. lunatus (lima bean)7 is specific to the ...

In cases of disputed parentage, the possibility of simultaneous occurrence of rare events in the population must be considered. PURPOSE--To report a case in which HLA-A/B recombination and homozygosity of a silent allele, typical of Negroes, in an individual apparently without this miscegenation were coexistent. METHODS--Alleged father, mother and dizygotic twin children were racially classified ...

OBJECTIVES:: Children undergoing cardiac surgery with cardiopulmonary bypass are susceptible to additional inflammatory and immunogenic insults from blood transfusions. We hypothesize that washing red blood cells and platelets transfused to these patients will reduce postoperative transfusion-related immune modulation and inflammation. DESIGN:: ...

An ARO/Rh Blood-Typing kit useful for students to visualize blood-typing activities and practice problem-solving skills with transfusion reactions is presented. The model also enables students to identify relationships between A, B, and Rh antigens and antibodies in blood and to understand molecular mechanisms involved in transfusion ...

Allogeneic peripheral blood hematopoietic stem cell transplantation (PBSCT) is presently being evaluated in a French randomized study comparing peripheral blood vs bone marrow. Cases of potentially lethal acute hemolysis have recently been reported after allogeneic PBSCT in the presence of a 'minor' ABO incompatibility. Patients were ...

Clinical and laboratory data are reviewed on 45 infants with systemic icterus born in Hiroshima. An attempt was made to determine why 25 of the infants developed kernicterus while 20 did not. The pattern of involvement and the histologic changes in the central nervous system in the kernicterus group were not essentially different from those in cases with Rh or ...

BackgroundSince the cloning in 1990 of cDNA corresponding to mRNA transcribed at the blood-group ABO locus, polymorphisms due to ethnic and/or phenotypic variations have been reported. Some subgroups have been explained at the molecular level, but unresolved samples are frequently encountered in the reference laboratory.ResultsABO ...

We correlated donor and recipient factors with graft outcome in 436 adult patients who underwent 462 liver transplants. Donor variables analyzed were age, gender, ABO blood group, cause of death, length of stay in the intensive care unit, use of pressors or pitressin, need for cardiopulmonary resuscitation, terminal serum ...

A common feature in the structures of GT-A-fold-type glycosyltransferases is a mobile polypeptide loop that has been observed to participate in substrate recognition and enclose the active site upon substrate binding. This is the case for the human ABO(H) blood group B glycosyltransferase GTB, where amino acid residues 177�195 ...

Rapid and informative ABO genotyping has become increasingly popular in forensic use. We developed a multiplex real-time polymerase chain reaction (PCR) approach to genotype ABO major groups and subgroups. Seven differently fluorophor-labeled displacing probes for O(1)(261delG), A(261G), A(796C/803C), B(796A/803C), O(2) (802G>A), ...

Analysis of single-nucleotide polymorphisms and their association with diseases and nondisease phenotypes is of growing importance in human biology studies. In this laboratory exercise, students determine the genetic basis for their ABO blood type; however, no blood is drawn. Students isolate genomic DNA from buccal mucosa cells that ...

The functions of the precursor H antigen for ABO blood group antigens are still not fully understood, particularly in cancer cells. In this study, we used hybridoma technology and NSY human colon cancer cells as an immunogen to generate a monoclonal antibody designated as MAb L9E10. The binding antigen of MAb L9E10 was identified as ...

Transformations of computer maps of geographic distribution of gene frequencies using basic mathematical statistical procedures are considered. These transformations are designated as statistical transformation of maps. Two transformation groups are considered: of one map separately and of a group of maps. Transformations possess a value beyond their use ...

We performed personal identification by DNA polymorphism using forensic specimens. DNA was purified by the potassium iodine method instead of the phenol extraction method. When DNA is amplified by PCR, there are inhibitors of PCR such as melanin in hairs or blood and inorganic salts in bone. This problem was solved by the potassium iodine method. The genotype of the ...

A quadrupole dielectrophoretic microdevice was utilized to examine the ABO-Rh dependencies on erythrocyte polarizations. This important step toward medical microdevice technology would transform key clinical blood tests from the laboratory into the field. Previous work in dielectrophoretic microdevices demonstrated that the large number of ...

... Title : Selected Contributions to the Literature of Blood Groups and Immunology. ... Secretion of Blood Group Substances and Lewis System. Part II. ...

... Title : Selected Contributions to the Literature of Blood Groups and Immunology. ... Secretion of Blood Group Substances and Lewis System. Part I. ...

... Blood Grouping and Phenotyping Reagents. -. Resources for You. ... Blood Grouping and Phenotyping Reagents. -. Licensed Product Approval Information. ...

The most clinically important blood group systems in transfusion medicine, excluding the ABO system, are the RH, Kell, and Kidd systems. Alloantibodies to antigens of these systems may be produced following blood transfusion or during pregnancy and can result in serious hemolytic transfusion reactions and hemolytic ...

Our study is intended to determine if the blood types recorded on identification cards carried by U.S. Air Force personnel contain significant errors. We studied 262 active duty Air Force personnel. Eleven errors in blood type information were identified, including seven Rh type errors and six ABO typing errors. Such errors may arise ...

All major ABO blood alleles are found in most populations worldwide, whereas the majority of Native Americans are nearly exclusively in the O group. O allele molecular characterization could aid in elucidating the possible causes of group O predominance in Native American populations. In this work, we studied exon ...