... Galileo Automated Blood Bank System - Add the Reverse ABO Group Assay. ... Product: Galileo Automated Blood Bank System-Add the Reverse ABO Group Assay. ...
Center for Biologics Evaluation and Research (CBER)
"Identification error between patient and blood product" is the main cause of ABO-incompatible blood transfusion, but "Phlebotomy error" also has serious consequences. In order to prevent ABO-incompatible transfusion, it is important to establish a management system of ...
PubMed
... alleles p, q, and r for the ABO blood group system were found to be 0.1295, 0. ... for alleles D and d of the Rh blood group system the allele frequencies were 0.9428 and ... ...
NBII National Biological Information Infrastructure
In the century since the discovery of the ABO blood groups, numerous associations between ABO groups and disease have been noted. However, the selection pressures defining the ABO distributions remain uncertain. We review published information on Plasmodium falciparum infection and ABO ...
... Title : ABO ANTIBODIES. I. METHODS FOR QUANTIFICATION OF ABO HEMOLYSINS AND SOLUBLE BLOOD GROUP SUBSTANCES A AND B. ...
DTIC Science & Technology
A Bioquest ESTEEM module in the Genetics Category. The purpose of this workbook is to compare several methods for calculating allele frequencies for ABO blood groups.
NSDL National Science Digital Library
... a specific blood type, characterized by the ABO blood groups and the presence or absence of the Rh factor (Rh positive or Rh negative). Because reactions can occur if a person receives a transfusion of improper blood type, a system of checks and balances (known ...
MedlinePLUS
Contents: Gammelgaard thesis; ABO system--Dunsfore Memorial; Secretion of blood group substances and Lewis system; M N and P systems; Anthropologic and other applications of blood grouping data; Landsteiner centennial; Grethe Hartmann monograph.
National Technical Information Service (NTIS)
ABO typing is the first test done on blood that is to be used for transfusion. A person must receive ABO-matched blood, as ABO incompatibility is the major cause of fatal transfusion reactions. Until now, this blood typing has been done manually, and there is therefore a ...
NASA Astrophysics Data System (ADS)
Limitations of polyacrylamide gel or agarose gel electrophoretic methods in genotyping research affect the interpreting of detection results. In order to develop a simple and reliable method for appraising results of ABO genotyping detection, the microfluidic chip analysis system was established by using microfluidic chip to replace the gel electrophoresis ...
The aim of this study was to investigate and evaluate the frequency of the antigens classifying the ABO and Rh blood groups in the Greek population. In this study the 3.5% were first generation immigrants with both their parents immigrants from countries of the USSR, while 1.2% had only one immigrant parent, while the other one was Greek. We compared the ...
as in humans. This new finding provides us not only an economical and attractive way to synthesize human blood Blood Group B Antigen Tetrasaccharide Wen Yi, Jun Shao, Lizhi Zhu, Mei Li, Mamata Singh, Yuquan Lu, 2004; E-mail: pgwang@chemistry.ohio-state.edu The histo-blood group ABO system is ...
E-print Network
With the aid of Eldon cards the distribution of the ABO blood groups and of the Rh factor (D) was investigated in different native ethnic groups (Kafirs, Kalash, Chitrali) in the Hindu Kush region of Afghanistan and Pakistan. All studied groups are characterized by a relatively high frequency of blood group gene A and extremely low ...
... using more complex phenotypic traits such as ABO blood type. Alternatively, the activity can be simplified, and completed ... or a more complex combination such as ABO blood type. More statistical analysi...
OBJECTIVE: The negative effects of cigarette smoking on human reproduction and on birth weight are well documented. On the other hand ABO system, encoding for glycosyltransferases, contributes to biosynthesis of antigens and oligosaccharide structures involved in blastocyst adhesion and intrauterine selection. In this paper we have searched for possible ...
Historically, forensic and clinical laboratories utilize serological techniques to identify ABO blood types. These techniques rely on the detection of ABO-associated proteins and are sensitive with very accurate results. This laboratory has simplified the identification of ABO types by taking advantage of ...
Two technics for the quantitative measurement of ABO hemolysins are described. The first involves the determination of the serum dilution which, in the presence of excess complement, lyses 50% of a standard red cell suspension (QH50). The second measures ...
Personality trait research has shown associations with many genes, prominently those of the catecholamine metabolism such as dopamine beta hydroxylase (DBH), catechol-O-methyltransferase (COMT), and monoamine oxidase A (MAOA). Because DBH gene is in linkage disequilibrium with ABO gene, there is reason to think that other catecholamine genes using the same substrate as DBH may ...
The selection and use of animals with blood group 0 in the process of transplanting pig organs or tissues into humans can positively contribute to the control of acute immune rejection due to differences in blood groups. Exon-specific PCRs for the porcine blood group A transferase gene against genomic DNA from either ...
... albopictus (Diptera: Culicidae) on Human Skin Among ABO Blood Groups, Secretors or Nonsecretors, and ABH AntigensYoshikazu Shiraia,b, ... Japan Abstract We demonstrated in this study that blood group...
The blood type of a person is a combination of ABO blood type and Rh factor. ... A child of parents with blood types A+ and B+ could have any blood type. ...
NASA Website
... of this website will be limited. Search Help? Blood Typing Formal name: ABO Grouping and Rh Typing ... antigens? 1. Do I need to know my blood type? Your blood will always be typed before ...
... India. ABSTRACT We studied the distribution of ABO blood group frequencies of the Galo and Mishing subtribes of ... to investigate the intertribal and temporal allelic variation. Blood groups O and AB s...
... studies on the Panggi are studies of ABO blood group polymorphism (Bhattacharjee 1954; Krithika et al. 2006), cultural ... 1994; Lego 2005). Among the Adi Panggi, ABO blood groups, anthropometric variatio...
The technique can be useful in detecting weak subgroups of the ABO blood group system. However, it is not possible to classify these weak subgroups into specific categories, e.g., A3, Am, or Ax, using this technique, since they do not segregate into well ...
Automated microplate blood-grouping systems rely on a pair of thresholds to determine whether reactions are positive or negative. The determination of these thresholds is a critical step in the quality control process for automated microplate blood grouping. A simple method has been developed for automatically setting these thresholds. ...
ABO blood groups and secretor status are important in clinical and forensic medicine and in relation to some diseases. There are geographic and racial differences in their frequencies, but the frequency of secretor status in different ABO blood group systems has not been determined yet. ...
PubMed Central
and induction of mutations among descendants of exposed animals. Genetic properties of each individual, such as ABO blood type and hair color in humans, are ...
A microfluidic platform developed for quantifying the dependence of erythrocyte (red blood cell, RBC) responses by ABO-Rh blood type via direct current insulator dielectrophoresis (DC-iDEP) is presented. The PDMS DC-iDEP device utilized a 400�170??m(2) rectangular insulating obstacle embedded in a 1.46-cm long, 200-?m wide inlet ...
Although a number of studies have demonstrated the influence of ABO blood group on plasma levels of von Willebrand factor (VWF), the nature of this association and its clinical importance is still largely unknown.In this review, the most recent advances in our understanding of the mechanisms by which ABO blood ...
SummaryBackgroundValidations of routinely used serological typing methods require intense performance evaluations typically including large numbers of samples before routine application. However, such evaluations could be improved considering information about the frequency of standard blood groups and their variants.MethodsUsing RHD and ABO population ...
Genotyping is useful to predict the expression of those RBC antigens for which antisera are difficult to obtain, to determine the probable phenotype of highly transfused patients, and can be used to test stored DNA when a blood sample is not available. This study assessed a sequence-specific primer (SSP)-based genotyping system for ...
There is growing epidemiological and molecular evidence that ABO blood group affects host susceptibility to severe Plasmodium falciparum infection. The high frequency of common ABO alleles means that even modest differences in susceptibility could have a significant impact on the health of people living in malaria endemic regions. We ...
ABO typing is the first analysis performed on blood when it is tested for transfusion purposes. The automated machines used in hospitals for this purpose are typically very large and the process is complicated. In this paper, we present a new micro blood typing system that is an improved version of our previous ...
A one-step Du test, developed for use in automated microplate systems, uses anti-D with 0.6 percent dextran to potentiate the reaction. Because the washing and reagent-adding steps of the antiglobulin test are not required, the Du test can be performed in the same microplate as the ABO/Rh test. A set of reactions prepared with this technique was visually ...
AbstractThe ABO histo-blood group system is the most important antigen system in transplantation medicine, yet no small animal model of the ABO system exists. To determine the feasibility of developing a murine model, we previously subcloned the human ...
that reduction of blood group antibody titer prior to kidney transplantation across the ABO barrier decreased showed that graft survival for kidney transplants across the ABO barrier was 79% at 1�4 years, 75% at 5. Similar success with ABO-incom- patible liver and kidney transplantations were also reported by ...
Dynamical algebras, of the so(3,2) and so(3) types, are obtained for a generalized Aharonov-Bohm plus oscillator (ABO) system. Two types of coherent states are introduced for this generalized ABO system. A (q,p)-analogue of this system is proposed that re...
During the 1950's and 60's as new blood group systems were identified, antigen distribution studies were performed in Europe and North America among Caucasians and American Blacks. However, to date only limited studies have been performed in Africa and Asia. Because of lack of knowledge of the antigen distribution of most other than ...
This study was aimed to establish a genotyping method to detect ABO group gene of fetus from peripheral blood of pregnant women for prenatal diagnosis of hemolytic disease of newborn (HDN) resulting from ABO blood group incompatibility. 4 pairs of primers were designed according to ABO ...
Lysates of heads, hind- and midguts of male and female Phlebotomus papatasi were found to contain lectins or lectin-like molecules capable of agglutinating human red blood cell types of the ABO(H) system and promastigotes of Leishmania aethiopica, L. major and L. donovani but not L. hertigi hertigi promastigotes or Crithidia ...
Human A, B, and O blood type is determined by the presence or absence of distinct carbohydrate structures on red blood cells. Type O individuals have ?-fucose(1?2)galactose disaccharides [O(H) structures] on their cell surfaces while in type A or B individuals, the O antigen is capped by the addition of an ?- N -acetylgalactosamine or ?-galactose residue, ...
The ABO histo-blood group antigens are best known for their important roles in solid organ and bone marrow transplantation as well as transfusion medicine. Here we report the synthesis of the ABO type III and IV antigens with a 7-octen-1-yl aglycone. Also described is an NMR study of the ABO type I to VI antigens, ...
Failure to develop antibodies to nonself A and B blood group antigens is well described after infant ABO-incompatible heart transplantation and suggests that exposure to incompatible ABO antigens early in life may lead to tolerance rather than immunogenicity. If this finding is also true following ABO-incompatible ...
A survey has been made to assess the evidential value of tests carried out on 660 casework penile swabs. Most were from suspects in sexual assaults and were examined to see if the donor had had recent anal, oral or vaginal intercourse. The swabs were tested for one or more of the following: blood, faeces, saliva, vaginal secretions, semen. Blood was seldom ...
Classical works dealing with the possibility of mother-child incompatibility with regard to basic ABO blood groups give contradictory conclusions (e.g.--Matsunaga et al. 1962, Thompson et al. 1991). Bioreproductive and population-genetic indicators have been studied in a sample of live births and in two pregnancy samples characterised by different "a ...
Classical works dealing with the possibility of mother-child incompatibility with regard to basic ABO blood groups give contradictory conclusions. Bioreproductive and population-genetic indicators have been studied in a sample of live births and in two pregnancy samples with different "a priori" and "a posteriori" risk assessment. The analysis points out ...
... States and internationally will enable critical information, such as ABO and Rh blood groups, to be clearly understood by health care professionals transfusing ...
Center for Drug Evaluation (CDER)
... The sites included in the study were: � University of Virginia - Charlottesville, VA � Heartland Blood Center - Aurora, IL � Univ. ...
... biology courses including: introductory biology and immunology at college and ... students. Through manipulation of the model cells, students practice ... ...
To examine genetic affinity among Oceanian populations, polymorphisms of exons six and seven of the ABO blood group gene (ABO) were investigated in three populations--Munda town, Paradise village, and Rawaki village--in the New Georgia group of the Solomon Islands. The Munda and Paradise populations consist of Austronesian ...
... The system supports the search and retrieval of eligible donors by various criteria including ABO, Rh, HLA and antigen profiles. ...
... December 17, 2004; Accepted: December 20, 2005Keywords: MALARIA, BLOOD GROUPS, ABO, MNSS, DUFFY, BRAZILIAN AMAZON REGION A large ... MNSs (glycophorins A and B), and the Duffy blood group antigen (Daniels...
ABO genotyping is often performed to identify the blood type of decomposed samples, which is difficult to be determined by a serological test. In this study, we developed a simple method for ABO genotyping using a DNA chip. In this method, polymerase chain reaction-amplified and fluorescent-labeled fragments in the ...
PurposeTo determine whether corneal graft survival over a five-year follow-up period was affected by ABO blood type compatibility in participants in the Cornea Donor Study undergoing corneal transplantation principally for Fuchs� dystrophy or pseudophakic corneal edema, conditions at low risk for graft rejection.DesignMulti-center prospective, ...
Anthropologists have assumed that reduced genetic diversity in extant Native Americans is due to a founder effect that occurred during the initial peopling of the Americas. However, low diversity could also be the result of subsequent historical events, such as the population decline following European contact. In this study, we show that autosomal DNA from ancient Native American skeletal remains ...
Patient safety in transplantation depends on accurate testing, transcription and transmission of the ABO types of the donor and recipient. Similar to 'near-miss' transfusion labeling errors, three cases of mislabeled ABO types on deceased donor kidney containers were recognized through a pretransplant verification process. Six steps to confirming the organ ...
Transplantation of hematopoietic progenitor cells from red cell-incompatible donors occurs in 30-50% of patients. Immediate and delayed hemolytic transfusion reactions are expected complications of red cell-disparate transplantation and both ABO and other red cell systems such as Kidd and rhesus can be involved. The immunohematological consequences of red ...
Determination of predicted blood group phenotype by determination of genotype has been performed since the 1990s. This evolved due to the rapid accrual of information surrounding the molecular basis of blood group antigen expression, which started in 1990 with ABO and RH systems and has now resulted in the ...
AIM: To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS: Using the University of Pittsburgh�s clinical pancreatic cancer registry, the blood donor database from our local blood bank (Central Blood Bank), and the ...
The macrocirculation in the head of three air-breathing species of Channa was examined with the aid of vascular corrosion replicas and a scanning electron microscopic study was conducted on the pseudobranch, choroid gland and lentiform body. Two facultative air-breathing murrels, C. punctata and C. gachua, and one obligate air-breather, C. marulius were examined. In all three, the air-breathing ...
The adiabatic Born-Oppenheimer approximation (ABO) has been the standard ansatz to describe the interaction between electrons and nuclei since the early days of quantum mechanics. ABO assumes that the lighter electrons adjust adiabatically to the motion of the heavier nuclei, remaining at any time in their instantaneous ground state. ...
The fucosylated ABH antigens, which constitute the molecular basis for the ABO blood group system, are also expressed in salivary secretions and gastrointestinal epithelia in individuals of positive secretor status; however, the biological function of the ABO blood group ...
BackgroundPlacental Protein 13 (PP13), an early biomarker of preeclampsia, is a placenta-specific galectin that binds beta-galactosides, building-blocks of ABO blood-group antigens, possibly affecting its bioavailability in blood.Methods and FindingsWe studied PP13-binding to erythrocytes, maternal blood-group ...
Interviewee: Matt Ridley DNAi Location:Genome>tour>genome spots>Blood groups Location: chromosome 9 gene name: ABO (galactosyl transferase) The ABO gene codes for an enzyme called galactosyl transferase and determines your blood group. In people with A and B blood groups, the gene ...
162 samples of blood from sensitized patients were investigated immunohematologically. All the patients were in need of blood transfusions. Immunization to HLA-antigens, to leukocyte and erythrocyte antigens was found in 74.0% and 25.4% of the patients, respectively. One patient (0.6%) had an extremely rare immunization to antigens D and c of Rh-Hr ...
BACKGROUND.: A novel immunosuppression protocol using rituximab and plasma exchange treatment was developed for ABO-incompatible living donor liver transplantation (ABO-I LDLT). The aim of this study was to investigate the kinetics of anti-blood type isoagglutinin titers and the number of blood B lymphocytes in ...
The system described here can distinguish between single and agglutinated erythrocytes by use of a non-flow fiber optic fluorometer. The method is capable of detecting cell-surface antigens and antibodies to cell-surface antigens present in blood. Significant features include high-efficiency fluorescent dyes that intercalate into cell membranes, a ...
Two Korean mummies (Danwoong-mirra and Yoon-mirra) found in medieval tombs in the central region of the Korean peninsula were genetically investigated by analysis of mitochondrial DNA (mtDNA), Y-chromosomal short tandem repeat (Y-STR) and the ABO gene. Danwoong-mirra is a male child mummy and Yoon-mirra is a pregnant female mummy, dating back about 550 and 450 years, ...
... India. ABSTRACT We studied the distribution of ABO blood groups among three little known subtribes of the Adi ... and Upper Siang districts of Arunachal Pradesh, India. Blood group O was the predominant...
ABO and Rhesus (Rh) blood group antigens are hereditary characters and are useful in population genetic studies, in resolving medico-legal issues and more importantly in compatibility test in blood transfusion practice. Data on frequency distribution of ABO and Rh-D in Niger-Delta region of Nigeria are not ...
ABO-incompatible living-donor lobar lung transplantation was performed in a 10-year-old boy with bronchiolitis obliterans (BO) after bone marrow transplantation (BMT) for recurrent acute myeloid leukemia (AML). His blood type had changed from AB to O since he underwent BMT and he had no anti-A/B antibody, and received type B and AB donor lobar lungs. To ...
We compared the results of routine blood tests for 102 blood donors' samples and 100 patients' samples collected in spray-dried K2EDTA, spray-dried K3EDTA, and liquid K3EDTA blood collection tubes to evaluate the impact of changes in formulation of the anticoagulant (K2EDTA vs.K3EDTA), its application (liquid vs. spray-dried), and tube ...
Noroviruses (NoVs) are a leading cause of viral gastroenteritis in humans. In the present study, the association between NoV susceptibility and the ABO histo-blood group was studied during 2 outbreaks of acute gastroenteritis in military units in Israel caused by genogroup II (GII) NoVs. The findings demonstrate that, unlike for genogroup I of NoV, there ...
An attempt has been made to interpret the quite rare distribution pattern of ABO blood group genes (p > 0.5000, q < 0.1000 and r < 0.5000) among the Prasun Kafirs and the Kalsh of the central Hindu Kush from the point of view of population genetics and ethnohistory. If we consider the different age groups of the Prasun sample it will be observed ...
OBJECTIVE: This study evaluated the outcome of liver grafts from ABO incompatible donors, focusing on biliary complications, and compared the results to an ABO compatible control group. Also, the expression of donor ABH antigens in the liver graft was analyzed. SUMMARY BACKGROUND DATA: The outcome of liver transplantation using an ABO ...
Advances in database and decision technologies provide abundant opportunities for implementing decision support systems for Information Operations specialists. This thesis describes, designs, and partially implements a system that provides information abo...
The national reference Center for blood groups checked samples of reagents and devices used in France for a definitive verification of pretransfusion ABO tests performed at the patient's bedside, as defined by French health authority regulations. The results of an initial inquiry was published in 1991. The new study shows no significant improvement of the ...
Cell surface carbohydrate antigens show changes in relation to differentiation, maturation and malignant transformation. The expression of type 2 chain ABH carbohydrate structures of the ABO histo-blood group system was investigated in 28 pleomorphic adenomas (PA) and normal parotid glands in order to study possible changes in the ...
An unusual blood group inheritance, that is, a phenotype O child from AB X O parents, was found in a Japanese family. Since two other children from the parents are blood type B, this is not a case of Cis-AB inheritance. The mother is not blood A/B chimera, and normal levels of blood group ...
A simple and reliable technique for removal of ABO incompatible marrow red cells is described. This method requires a blood cell processor and third party red cells are used as a shelf. Using this technique, nine children age 0.5-11.5 years received allogeneic bone marrow transplantation from ABO incompatible donors. A median of 4.8 ml ...
Erythrocytic group antigens represent a genetically stably determined trait. Investigation of antigens of the said system in different regions is of the greatest importance in terms of both the creation of demographic data of the region as well as practical medicine, especially for transplantology and transfusiology. The peripheral or venous blood of 232 ...
... No. % No. % No. % TRALI 29 47% 35 56% 34* 65% 98 55% HTR (non-ABO) 16 26% 9 14% 2 4% 27 15% Microbial ...
Recipients of ABO incompatible allogeneic HSCT present with unusual ABO groups and crossmatch problems accompanied by change of the ABO group from that of the host to the donor. We report on a patient undergoing major ABO incompatible allogeneic HSCT (donor/recipient: A/O) whose blood group was ...
We statistically verify the Hardy Weinberg principle in genetics by investigating the independence of ABO-blood types of married couples. The allelic frequencies derived from the phenotypic frequencies in ethnic groups via the Hardy Weinberg principle are used to define a genetic distance (called the blood distance in this work) between two groups. The ...
The distributions of ABO, rhesus, and Lewis blood group antigens were studied in patients with alcoholic cirrhosis, alcoholic pancreatitis, chronic active hepatitis, and primary biliary cirrhosis. There were no differences in frequencies of ABO and rhesus blood group antigens between the groups or in comparison ...
The ABO relationships of 150 corneal transplant recipients and their donors were evaluated as were IgG and IgM isoagglutinins in recipients receiving grafts from ABO-incompatible donors. The HL-A antigens of 43 corneal transplant recipients and their donors were determined as were the cross-matches of donor lymphocytes in selected cases. No relationships ...
An ARO/Rh Blood-Typing kit useful for students to visualize blood-typing activities and practice problem-solving skills with transfusion reactions is presented. The model also enables students to identify relationships between A, B, and Rh antigens and antibodies in blood and to understand molecular mechanisms involved in transfusion ...
ERIC Educational Resources Information Center
Blood groups according to ABO and Rh systems were tested in 137 ulcer patients as well as the secretory state. The titre of blood group ABH antigens was determined in the same patients, secreted in saliva and gastric juice. The results are compared with those obtained from the examination of a control group of 30 ...
Comparative analysis of allelic variation of a gene sheds light on the pattern and process of its diversification at the population level. Gene families for which a large number of allelic forms have been verified by sequencing provide a useful resource for such studies. In this regard, human blood group-encoding genes are unique in that differences of cell surface traits ...
Research on genetic markers in the fields of forensic medicine and human genetics did not begin in earnest until 1968. Study of an extended family in Wakayama Prefecture resulted in the discovery of the variant Bm type in the ABO blood group system. This family of nearly 40 members composed of Group A, B, O and AB spouses and type Bm ...
In sexual assaults against women, one key to identifying the suspect is ABO phenotyping or the typing of other polymorphic markers of the seminal fluid in the victim's vagina. However, ABO phenotyping is frequently unsuccessful, since mixtures of fluids cannot be separated to be subjected to conventional methods for the detection of antibody or antigen ...
P1 and ABO antigens and bacterial stx genotypes might influence the risk of developing hemolytic uremic syndrome (HUS) after Escherichia coli O157:H7 infections. We determined ABO status and P1 antigen expression in 130 infected and 17 uninfected children, and we determined the stx genotype of the infecting isolate. P1 expression was weakly and directly ...
Few studies have addressed the incidence of graft-versus-host disease (GVHD) or survival after ABO-incompatible allogeneic peripheral blood stem cell transplantation (PBSCT). We analyzed the clinical outcome of ABO incompatibility after allogeneic PBSCT. A total of 89 consecutive adult patients with hematological diseases including 49 ...
Results of HLA-A, B and C typing as well as haplotype frequencies in the Nahuas, who are the predominant Indian group in Mexico are presented. ABO and Rh blood groups show the genetic homogeneity of this population, since all of them were group O and Rh+. The most frequent antigens and haplotype are in general, the same as in some, but not all Amerindian ...
In addition to the issues concerning blood transfusions in general, special considerations apply to transfusing neonates. Young infants' plasma may contain maternal antibodies to ABO blood group antigens instead of the naturally occurring anti-ABO antibodies normally present in older patients. This facilitates the ...
Background:ABO incompatibility in maternal�fetal relationship has been shown to cause hemolytic disease of the newborn (HDNB); a survey which is not yet done in this locality.Aim:Frequency of ABO blood group maternal-fetal incompatibility, maternal iso-agglutinins, and immune agglutinins quantitation was carried out in Osogbo, Osun ...
Analysis of single-nucleotide polymorphisms and their association with diseases and nondisease phenotypes is of growing importance in human biology studies. In this laboratory exercise, students determine the genetic basis for their ABO blood type; however, no blood is drawn. Students isolate genomic DNA from buccal mucosa cells that ...
Gene expression is driven by promoters, enhancers, silencers, and other cis-regulatory elements upstream and downstream of the gene. Previous studies of the regulation of human ABO gene transcription have focused mainly on the 5' region, including the core promoter and the region proximal to it. However, as the involvement of the 3' flanking region in transcriptional ...
An immunological and immunogenetic investigation of coal worker's pneumoconiosis (CWP) was conducted. Four geographic regions of study were established, depending on the type of coal mined in the region. Blood samples were taken from 358 workers with no disease, simple CWP, or complicated CWP. Samples were tested for histocompatability, blood ...
Energy Citations Database
Purpose of reviewThis review summarizes recent advances in our understanding of the interaction between malaria parasites and blood group antigens and discusses how the knowledge gleaned can be used to target the development of new antimalarial treatments and vaccines.Recent findingsStudies of the interaction between Plasmodium vivax and the Duffy antigen provide the clearest ...
Transplantation or transfusion with ABO disparity is a cause for rejection or for severe hemodynamic alterations. ABO groups in pigs are commonly an unknown variable, which has been previously assessed by means of hemagglutination tests or immunohistochemical procedures on tissues. Herein, we have reported a simple method using commercial microcards for ...
A quadrupole dielectrophoretic microdevice was utilized to examine the ABO-Rh dependencies on erythrocyte polarizations. This important step toward medical microdevice technology would transform key clinical blood tests from the laboratory into the field. Previous work in dielectrophoretic microdevices demonstrated that the large number of ...
Following federal and provincial reviews of the blood system, the Canadian province of Quebec passed a series of legislative and administrative measures to improve blood safety, including the establishment of a hemovigilance system, and made infrastructure and human resource investments to support their ...
Phenotype distributions of some genetic polymorphisms are reported in a sample of 721 diabetics and 515 non-diabetic, non-blood donor controls. Reference is also made, in the case of the ABO and Rhesus systems, to previously published results for blood donors resident in the Durham area. Non-insulin-taking ...
The International Safeguards Data Management System (ISADAM) comprises a set of programs for use with the ADABAS data base management system and is intended to help the Safeguards Authority to make efficient and effective use of the accounting reports abo...
Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States. Recent reports, including genome-wide association studies and self-reported blood serotype studies, have shown that individuals of European ancestry who carry non-O blood group are at an increased risk of developing pancreatic cancer. Two recent genome-wide ...
Our study is intended to determine if the blood types recorded on identification cards carried by U.S. Air Force personnel contain significant errors. We studied 262 active duty Air Force personnel. Eleven errors in blood type information were identified, including seven Rh type errors and six ABO typing errors. Such errors may arise ...
In cases of disputed parentage, the possibility of simultaneous occurrence of rare events in the population must be considered. PURPOSE--To report a case in which HLA-A/B recombination and homozygosity of a silent allele, typical of Negroes, in an individual apparently without this miscegenation were coexistent. METHODS--Alleged father, mother and dizygotic twin children were racially classified ...
Aqueous extracts of human neoplastic and adjacent normal colonic mucosa were investigated for hemagglutination inhibition of both the anti-A serum and the Dolichos biflorus lectin. The anti-A antiserum was inhibited by the extracts from neoplastic tissues to a much higher extent than by that from normal mucosa; the inhibition was strictly dependent on the blood group and the ...
The phenomenon of accommodation in recipients of blood group ABO incompatible kidney transplantation (iKTx), in which grafts survive despite the presence of blood group A or B antigen in the graft and the presence of corresponding antibodies in the recipient's blood, is not uncommon. ...
Why certain individuals progress to severe dengue disease is unknown. In this study, blood groups associated with dengue disease were investigated. ABO phenotypes were identified by use of serum from 399 patients with dengue-virus infection who participated in a cohort study. ABO blood-group frequencies were ...
Rapid user-friendly ABO-Rh blood typing kits (Eldon Home Kit 2511, ABO-Rh Combination Blood Typing Experiment Kit) were evaluated to determine their accuracy when used under simulated military field conditions and after long-term storage at various temperatures and humidities. Rates of positive tests between ...
Clinical and laboratory data are reviewed on 45 infants with systemic icterus born in Hiroshima. An attempt was made to determine why 25 of the infants developed kernicterus while 20 did not. The pattern of involvement and the histologic changes in the central nervous system in the kernicterus group were not essentially different from those in ...
Background: Generalised immune stimulation may follow vaccination causing increased antibody titres of nonvaccine-related antibodies or bystander antibodies, including those to human leukocyte antigens (HLA) and ABO blood group antigens. HLA antibodies may lead to transfusion-related acute lung injury. High-titre ABO antibodies may ...
BackgroundElevated serum soluble E-selectin levels have been associated with a number of diseases. Although E-selectin levels are heritable, little is known about the specific genetic factors involved. E-selectin levels have been associated with the ABO blood group phenotype.Methods and ResultsWe performed a high-resolution genome-wide association study of ...
Architecture reconstruction is the process where the 'as-built' architecture of an implemented system is obtained from the existing legacy system. This is done through a detailed analysis of the system using tool support. The tools extract information abo...
BackgroundPersistent anti-donor isoagglutinins after major ABO blood group incompatible hematopoietic stem cell transplantation may cause delayed red blood cell engraftment and post-transplant pure red cell aplasia.Design and MethodsWe investigated the effect of pretransplant anti-donor isoagglutinin reduction by in vivo absorption ...
The Phayengs and Khurkhuls are sections of the Meiteis, the largest community in Manipur, India. Racially they are Mongoloids, and marry mostly among themselves. The present study reveals the frequencies of ABO blood groups as A1 (36.54%), B (28.85%), O (25.96%) and A1B (8.65%) in the Phayengs (n = 124) and A1 (39.84%), B (21.14%), O (22.76%) and A1B ...
Both Japan Society of Blood Transfusion and Cell Therapy and Japan Society of Anesthesiologists have made a "Guideline of Management at Critical Bleeding in the Operating Room" in 2007. Since 2008, Japan Red Cross Blood Center (JRC) introduced leuko-reduction filter and diversion technique to prevent bacterial contamination. This improvement can easily ...
Rapid and informative ABO genotyping has become increasingly popular in forensic use. We developed a multiplex real-time polymerase chain reaction (PCR) approach to genotype ABO major groups and subgroups. Seven differently fluorophor-labeled displacing probes for O(1)(261delG), A(261G), A(796C/803C), B(796A/803C), O(2) (802G>A), A(2) (1059delC), and ...
Phenotype studies of ABO blood groups in most Amerindian populations revealed the exclusive presence of group O. Since group O is the result of the absence of glycosyltransferase activity, its molecular bases may be heterogeneous. We carried out ABO blood group genotyping by analysis of DNA of 30 Indians from 2 ...
Six textbooks and two Internet sites show different structures for the A, B, and O(H) antigens of the ABO(H) blood group. However, none of the structures identified as the A, B, and O(H) antigens are correct. The O(H) antigen is a disaccharide, on which the trisaccharide A and B antigens are synthesized. The structures shown in the textbooks and at the ...
As part of a multidisciplinary survey of populations in the Banks and Torres Islands of Vanuatu and the Southern and Central Districts of the Solomon Islands, nearly 2,400 persons have been tested for ABO blood groups and a number of serum protein and red cell enzyme genetic marker systems. For the ABO ...
Between February 1971 and October 1980, 34 patients with leukemia or aplastic anemia received bone marrow transplants from HLA-identical siblings whose lymphocytes did not react in a mixed leukocyte culture. The donors of 10 patients were ABO-incompatible, and for five pairs the ABO incompatibility was major. Plasma exchanges followed by a red ...
Naval Aviation Oxygen Systems (NAOS) include the On-Board Oxygen Generating System (OBOGS), Liquid Oxygen (LOX) System, and the Aviators Breathing Oxygen (ABO) Contaminant Analyzer. All three programs have reached Full Operational Capability and are in the Operations and Support phase of the Defense Acquisition ...
A method and system for converting the chemical energy of methane to electrical energy. Methane is thermally decomposed to hydrogen and carbon in a decomposing unit at a temperature not less than about 1200(degree)K and at a pressure at least slightly abo...
Paternity is based on biological analyzes that have drastically developed during the past 20 years. According to scientific developments, paternity testing was based on red blood groups studies, the analysis of red cell enzymes and plasma proteins polymorphisms, the typing of the HLA antigens, and the DNA polymorphism in its various forms. This study aims at comparing two ...
It is well known that Phaseolus species contains lectins of various specificities 1-4. Runner bean5 and different varieties of Ph.coccineus described by Ochoa et al6, are not specific to human blood groups. They react indistinctly with erythrocytes of the ABO system. However the lectin of Ph. lunatus (lima bean)7 is specific to the ...
The discovery of ABO blood group was a major step in mastering transfusion therapy. Karl Landsteiner (1868-1843) was the author of this discovery. This paper retraces the hard career of this American scientist of Austrian origin, and describes the circumstances that led his research to the discoveries, which were turning points in the history of the ...
Percentage distributions of nine genetic markers, including ABO blood type, secretor ability, haptoglobin type, transferrin type, and group specific component type, are presented and discussed by age, sex, race, geographic region, family income and parent...
of BabA, the H. pylori ABO Blood Group Antigen Binding Adhesin Marina Aspholm-Hurtig,1 Giedrius Dailide,2 * Thomas Bore�n1,18 * Adherence by Helicobacter pylori increases the risk of gastric disease. Here, we by specialist binding in blood group O�dominant human populations. The gastric pathogen Helicobacter pylori
2,140 pregnant Sudanese women attending the antenatal clinic in Omdurman Maternity Hospital during the period November 1975 to December 1976 had ABO and Rh typing performed. Their sera were also screened by a modified papain enzyme technique for the presence of atypical antibodies. The rate of Rhesus immunization, the frequency distribution of blood ...
Average blood loss after total knee arthroplasty (TKA) usually ranges from 1500 to 1900 cc, including both the postoperative drain and hidden blood loss. This represents about 46% of TKA patients requiring postoperative blood transfusion. Not only the risks of disease transmission but also those of ABO ...
A recent genome-wide association study (PanScan) identified significant associations at the ABO gene locus with pancreatic cancer risk; however, the mechanisms underlying these associations and the influence of specific ABO genotypes remain unknown. We determined ABO genotypes (OO, AO, AA, AB, BO, BB) in 1534 cases and 1583 controls ...
Chikungunya fever is a viral disease transmitted to humans by the bite of CHIKV virus infected Aedes mosquitoes. During monsoon outbreak of chikungunya fever, we carried out the genetic predisposition to chikungunya in disease affected 100 families by doing blood group (ABO) tests by focusing on individuals who were likely to have a risk of chikungunya and ...
BackgroundPrevious studies have examined the association between ABO blood group and the risk of some malignancies. However, no prospective cohort study to date has examined the association between ABO blood group and the risk of skin cancer.Methodology/Principal FindingsUsing two large cohorts in the US, we ...
The most clinically important blood group systems in transfusion medicine, excluding the ABO system, are the RH, Kell, and Kidd systems. Alloantibodies to antigens of these systems may be produced following blood transfusion or during pregnancy and can ...
... CARDIOVASCULAR SYSTEM), PATHOLOGY, PHYSIOLOGY, BLOOD VESSELS, BLOOD CIRCULATION, BLOOD PRESSURE, HEART, BLOOD ...
... BLOOD, *HYDROSTATIC PRESSURE, PRESSURE, RHEOLOGY, BLOOD COAGULATION, ANTICOAGULANTS, BLOOD CIRCULATION ...
... ACCELERATION TOLERANCE, *CARDIOVASCULAR SYSTEM), BLOOD VOLUME, BLOOD CIRCULATION, BLOOD PRESSURE, BLOOD ...