We injected botulinum toxin into the horizontal rectus muscles of the right eyes of two patients who
NASA Technical Reports Server (NTRS)
We investigated the pathogenesis of acquired pendular nystagmus (APN) in six patients, three of whom
Nystagmus can be associated with strong discomfort due to oscillopsia, blurry vision and dizziness. Since generally no curative treatment methods exist, studies focus on potential pharmaceuticals to dampen the nystagmus. An overview is given on which forms of nystagmus can be treated with what kind of pharmacological substances and ...
PubMed
The decision whether a nystagmus is congenital or acquired may be difficult and is of importance in patients presenting with neurological complaints. In this article, established diagnostic criteria are critically reviewed with particular emphasis on types of nystagmus waveform and their relationship to pursuit and optokinetic ...
PubMed Central
BackgroundPharmacological treatment has been successful in some forms of acquired neurological nystagmus. However, drugs are not known to be effective in idiopathic infantile nystagmus or nystagmus associated with ocular diseases.MethodsThe authors retrospectively analysed Snellen visual acuity (VA), subjective ...
Pathological forms of nystagmus and their visual consequences can be treated using pharmacological, optical, and surgical approaches. Acquired periodic alternating nystagmus improves following treatment with baclofen, and downbeat nystagmus may improve following treatment with aminopyridines. Gabapentin and ...
A patient with multiple sclerosis presented with oscillopsia due to an acquired pendular nystagmus that was dissociated in amplitude, being larger in the eye with a relative afferent pupil defect. Eye movement recordings showed an unusual dissociation in nystagmus frequency as well. Although the frequencies differed, the eyes remained ...
Two unusual cases of monocular pendular nystagmus in patients with multiple sclerosis are reported. One patient showed regular horizontal oscillations of the right eye in abduction, associated with right abduction paresis. The second patient had a similar abnormal eye movement of the left eye in adduction, with partial left internuclear ophthalmoplegia. Such eye ...
A 24-year-old woman presented with nystagmus and head tremor. Both were transient and could be executed simultaneously at different frequencies of oscillation. It is unusual for these two movements, which can be voluntary, to occur together. Suspicions of an acquired disease were not confirmed on further investigation using DC-coupled electro-oculography ...
Some characteristics of vertical optokinetic nystagmus and after-nystagmus, in particular, its up/down gain asymmetry, are known to be influenced by gravity direction, which is basically perceived by otolith organs. However, how such an information of gravity direction is processed within the central nervous system is not well understood, even though the ...
The ocular motor system consists of several subsystems, including the vestibular ocular nystagmus saccade system, the pursuit system, the fixation and gaze-holding system and the vergence system. All these subsystems aid the stabilization of the images on the retina during eye and head movements and any kind of disturbance of one of the systems can cause instability of the ...
... of or diminished pupillary responses; nystagmus; seizures; and dysphagia) or �nonspecific� (e.g., emaciation; decreased appetite; dehydration; ... and/or tremors, ataxia, and circling, but also dysphagia,...
NBII National Biological Information Infrastructure
We report the case of a 12-year-old boy presenting with acquired horizontal nystagmus, headaches, and vertigo. CT, MRI, viral tests, and the Lyme disease test were at first negative. We made the diagnosis of neuroborreliosis based on a repeated Lyme disease test and lumbar puncture revealing intrathecal synthesis of specific antibodies. Adjusted antibiotic ...
We conducted a masked, crossover, therapeutic trial of gabapentin (1,200mg/day) versus memantine (40 mg/day) for acquired nystagmus in 10 patients (aged 28-61 years; 7 female; 3 multiple sclerosis [MS]; 6 post-stroke; 1 post-traumatic). Nystagmus was pendular in 6 patients (4 oculopalatal tremor; 2 MS) and jerk upbeat, hemi-seesaw, ...
We conducted a masked, cross-over, therapeutic trial of gabapentin (1200mg/day) versus memantine (40mg/day) for acquired nystagmus in 10 patients (28�61 years; 7 female; MS: 3, post-stroke: 6, post-traumatic: 1). Nystagmus was pendular in 6 patients (oculopalatal tremor: 4, MS: 2) and jerk upbeat, hemi-seesaw, torsional, or ...
Periodic alternating nystagmus consists of involuntary oscillations of the eyes with cyclical changes of nystagmus direction. It can occur during infancy (e.g. idiopathic infantile periodic alternating nystagmus) or later in life. Acquired forms are often associated with cerebellar dysfunction arising due to ...
SummaryMany reports have appeared in the medical literature concerning the clinical examination at the bedside of patients with vertigo and, even if few controversial opinions exist, the observation of one or more kinds of nystagmus is generally regarded as suggesting an organic aetiology. So far, the presence of nystagmus has been generally considered to ...
Design: Observational and experimental study. Methods: We carried out a phenotypic study of a unique four generation family with nystagmus. We performed genetic linkage studies including a genome wide search. Results: Affected family members developed vestibulocerebellar type nystagmus in the first two years of life. A higher incidence of strabismus was ...
Purpose: The adaptive strategies adopted by individuals with infantile nystagmus syndrome (INS) during reading are not clearly understood. Using eye movement recordings we have identified ocular motor strategies used by patients with INS during reading. Methods: Eye movements were recorded at 500Hz in 25 volunteers with INS and 7 controls when reading paragraphs of text ...
We review current pharmacological treatments for peripheral and central vestibular disorders, and ocular motor disorders that impair vision, especially pathological nystagmus. The prerequisites for successful pharmacotherapy of vertigo, dizziness, and abnormal eye movements are the "4 D's": correct diagnosis, correct drug, appropriate dosage, and sufficient duration. There are ...
Regulatory mechanism and brain damage in secondary nystagmus caused by caloric or rotary stimulation
Study of reduction of nystagmus, disorientation and nausea in human subjects living for several days
... Title : HABITUATION OF VESTIBULAR NYSTAGMUS IN THE CAT DURING SUSTAINED AROUSAL PRODUCED BY D-AMPHETAMINE. ...
DTIC Science & Technology
Four French West Indian women complained of oscillopsia and were found to have an acquired eye movement disorder. In 3 of them, different types of nystagmus were found, including upbeat, downbeat, and central form of vestibular nystagmus. One developed opsoclonus-myoclonus syndrome. Three patients had neuromyelitis optica antibodies, ...
Vertigo and dizziness are not independent disease entities, but instead symptoms of various diseases. Accordingly, a variety of treatment approaches are required. Here we review the most relevant drugs for managing dizziness, vertigo, and nystagmus syndromes. It is important to differentiate symptomatic treatment of nausea and vomiting with, for example, dimenhydrinate and ...
To ensure high acuity vision, eye movements have to be controlled with astonishing precision by the oculomotor system. Many human diseases can lead to abnormal eye movements, typically of the involuntary oscillatory eye movements type called nystagmus. Such nystagmus can be congenital (infantile) or acquired later in life. Although the ...
... an involved family. How does nystagmus affect a child�s visual development? What will the vision be as an adult? The visual development of a child with nystagmus is quite variable. Some children with ...
MedlinePLUS
The amplitude of nystagmus multiplied by its frequency gives a value commensurate to the velocity of
... Accession Number : AD0722129. Title : Nystagmus and Eye Deviation in the Environments of Flight and Space Travel,. Corporate ...
... Accession Number : AD0784509. Title : Heavy Water Nystagmus and Effects of Alcohol. Descriptive Note : Research paper,. ...
... This approach yields an evenly sampled SPV estimate without resorting to ... decision logic common to other nystagmus analysis programs. ...
The report describes administrative approval of a request for financial assistance to abolish existing grassed runways, acquired land (15 acres) for runway extension to the north of existing Airport Property, construct a new runway and runway lighting sys...
National Technical Information Service (NTIS)
We report a case showing apogeotropic nystagmus with the lesion of the brain stem, and discuss a possible mechanism of central apogeotropic nystagmus. The case was a 73-year-old male. We analyzed his nystagmus three-dimensionally. He showed apogeotropic nystagmus. Axis angles of slow phase eye velocity of his ...
Pyrroxan and dimenhydrinate exhibit comparable anti-seasick effects in the test involving maximal and submaximal statokinetic load. Pyrroxan somewhat more significantly increases the vestibular stability, predominantly in humans with inherently high and medium stability, whereas dimenhydrinate is also effective in humans with low resistance to seasick. Pyrroxan primarily decreases the statokinetic ...
Purpose: The aims of the present population-based, cross-sectional study were to examine the frequency and type of strabismus, refractive errors and nystagmus in children and young adults with Down syndrome (DS) in Macedonia and Croatia. Methods: A total of 170 unselected children and young adults with DS aged 1-34 years were examined for ocular findings. The ocular ...
The Arnold-Chiari malfomation is typically associated with downbeat nystagmus. Eye movement recordings in two patients with Arnold-Chiari malfomation type 1 showed, in addition to downbeat and gaze evoked nystagmus, intermittent nystagmus of skew. To date this finding has not been reported in association with Arnold-Chiari malfomation. ...
Two devices are described which facilitate measurement and analysis of nystagmus. One device requires manual alignment of a crosshair with the nystagmus slope. This process is much faster than unaided manual scoring because (1) the mechanical aid in slope...
Following unilateral labyrinthectomy or inactivation of one horizontal semicircular canal in cats, a horizontal positional nystagmus was observed when the cat, after ingesting alcohol, was held with the head up or with the head down. This nystagmus was to...
Effect of visual stimulation on nystagmus, from data of electronystagmography, in presence of tumors
Effect of changing resultant linear acceleration relative to human subject on nystagmus generated by
... Abstract : A persistent horizontal nystagmus response is elicited when a man is rotated at constant velocity about an Earth-horizontal axis. ...
... Title : Nystagmus Responses During Triangular Waveforms of Angular Velocity About the Y- and Z-Axes. Descriptive Note : Joint rept.,. ...
... BIRDS, *VESTIBULAR APPARATUS), ANATOMY, PHYSIOLOGY, STRESS(PHYSIOLOGY), MOMENTUM, NYSTAGMUS, PROPRIOCEPTION. ...
... The activity of the muscles in the rapid phases of a nystagmus is always connected with the appearance of short biphase action potentials in the ...
... Title : THE EFFECT OF CHANGING THE RESULTANT LINEAR ACCELERATION RELATIVE TO THE SUBJECT ON NYSTAGMUS ...
... NYSTAGMUS, NOISE, VIBRATION, ULTRASONIC RADIATION ... SYSTEMS, MONITORS, TELEMETER SYSTEMS, ELECTROPHYSIOLOGY ...
... PERFORMANCE(HUMAN), MOTOR REACTIONS, MUSCLES, RESPONSE( BIOLOGY), NYSTAGMUS, HYPNOSIS, BLOOD PRESSURE ...
... HUMAN), AVIATION MEDICINE, NYSTAGMUS, TRAINING, VESTIBULAR APPARATUS, CORIOLIS EFFECT, STIMULATION(PHYSIOLOGY ...
... ON THE ELICITATION OF SECONDARY AND INVERTED PRIMARY NYSTAGMUS FROM THE CAT BY UNILATERAL CALORIC IRRIGATION,. ...
In parabolic flight experiments, postrotary nystagmus is as found to be differentially suppressed in
... OF AROUSAL AND ITS EFFECTS ON HUMAN VESTIBULAR NYSTAGMUS INDUCED BY CALORIC IRRIGATION AND ANGULAR ...
... ASTRONAUTS, TRAINING, WEIGHTLESSNESS, NYSTAGMUS, VESTIBULAR APPARATUS, ELECTROPHYSIOLOGY, CHLORELLA, USSR. ...
... ANTIEMETICS, *NYSTAGMUS, DRUGS, INGESTION(PHYSIOLOGY), SCOPOLAMINE, TRANQUILIZERS, AMPHETAMINES, DOSAGE. ...
Research over the past 20 years has provided a clearer understanding of the pathogenesis of most forms of nystagmus and other ocular oscillations. To the clinician, these advances translate into greater accuracy of nystagmus as a diagnostic sign. However, to capitalise on these advances, it is important to systematically examine eye movements and interpret ...
... TOLERANCE, EXERCISE(PHYSIOLOGY), DOSIMETRY, EXTREMELY LOW FREQUENCY, NYSTAGMUS, BIOFEEDBACK, SPEECH THERAPY. ...
... NYSTAGMUS, AUDITORY SIGNALS, VESTIBULAR APPARATUS, PSYCHOPHYSICS, PROPRIOCEPTION, ADAPTATION(PHYSIOLOGY ...
... NYSTAGMUS, AVIATION PERSONNEL, SELECTION, TRAINING, FATIGUE(PHYSIOLOGY), BIOLOGICAL RHYTHMS, PATHOLOGY. ...
... This movement is usually the consequence of reflex excitation of the extra ocular muscles associated with stimulation of the semicircular canals. ...
...2011-04-01 2011-04-01 false Nystagmus tape. 886.1905 Section 886.1905 Food and...Diagnostic Devices § 886.1905 Nystagmus tape. (a) Identification. Nystagmus tape is a device that is a long, narrow...
Code of Federal Regulations, 2011
We describe a patient with Wernicke's encephalopathy who showed spontaneous upbeat nystagmus with decelerating slow phases that changed to downbeat nystagmus during upward gaze and increased during downward gaze. He also showed horizontal gaze-evoked nystagmus and impaired upward smooth pursuit. Magnetic resonance imaging demonstrated ...
A prospective examiner-blind, cross-over study was conducted to compare the efficacy of memantine (40 or 60 mg/day) and gabapentin (1,200 mg/day) as therapy for acquired fixational pendular nystagmus (APN) in 11 patients with multiple sclerosis. APN was documented in 20 eyes by electrooculography (EOG). The primary objective of the study was an at least ...
Nictitating membrane movement and multiple-unit activity in the somatosensory cortex were recorded from rabbits during paired (N=6) and unpaired (N=5) presentations of a tone conditioned stimulus (CS) and an airpuff unconditioned stimulus (US). A behavioural conditioned response (CR) to the CS and an accompanying neural response in the somatosensory cortex developed only in the paired group. ...
PURPOSE: To describe a treatable form of nystagmus. METHODS: Two patients recently evaluated at the Mayo Clinic had experienced various forms of oscillopsia, imbalance, and worsening symptoms with a Valsalva maneuver. Close inspection of the eye revealed a subtle rotatory nystagmus that was synchronous with the heartbeat. RESULTS: The two patients had ...
Involvement of the superior semicircular canal (SSC) in benign paroxysmal positional vertigo (BPPV) is rare. SSC BPPV is distinguished from the more common posterior semicircular canal (PSC) variant by the pattern of nystagmus triggered by the Dix-Hallpike position: down-beating torsional nystagmus in SSC BPPV versus up-beating torsional ...
BACKGROUND/AIMS�Periventricular leucomalacia (PVL) is a lesion in the immature brain involving the optic radiation. Children with PVL have visual problems including crowding, visual field defects, strabismus, and visual perceptual/cognitive deficits, together with nystagmus. They often have optic nerve hypoplasia seen either as small discs or as large cupping of normal sized ...
Long-associated with transportation ('railroad nystagmus'), optokinetic (OPK) nystagmus is an eye-movement reaction which occurs when a series of moving objects crosses the visual field or when an observer moves past a series of objects. Similar continual...
Police officers follow procedures set forth in the NHTSA/IACP curriculum when they administer the Standardized Field Sobriety Tests (SFSTs) to suspected alcohol-impaired drivers. The SFSTs include Horizontal Gaze Nystagmus (HGN) test, Walk-and-Turn (WAT) ...
A study was conducted on the relationship between vertical optokinetic nystagmus and motion sickness on healthy males under conditions of simulated weightlessness. The data demonstrated that factors affecting the vestibular apparatus (primarily optolithic...
A patient with suspected brain stem glioma involving the area of the left vestibular nuclei and cerebellar peduncle, developed paroxysmal alternating skew deviation and direction changing nystagmus after biopsy of the inferior cerebellar vermis resulting in destruction of the uvula. Between attacks she had right over left skew deviation with asymptomatic right beating ...
A case of chronic subdural haematoma in the posterior fossa, secondary to anticoagulant treatment, is presented. The unusual clinical presentation of vertigo and nystagmus and the atypical CT are discussed. This seems to be the first report to describe a chronic subdural haematoma in the posterior fossa in an alive adult.Images
A persistent horizontal nystagmus response is elicited when a man is rotated at constant velocity about an Earth-horizontal axis. This response comprises two components: a directional bias and a cyclic modulation of the bias level. Observations were made ...
Electronystagmography (ENG) is one of the modern methods for objective recording of nystagmus, its quantitative and qualitative assessment. It is used more and more often in clinical practice. A brief review of the history of recording of nystagmus and a ...
An attempt was made to extend the investigation of FOKN (Fixation Optokinetic Nystagmus) to a new category of problems, hand movements. The purpose of this work was to elucidate whether FOKN responds to the extent of visual participation in motor acts. (A...
The problem was to compare performance limits and nystagmus induced by angular accelerations about the pitch and the yaw axes. Sinusoidal torsional oscillation degraded subjects' performance of a compensatory tracking task because inappropriate nystagmic ...
An annotated bibliography of translations of foreign-language articles is presented. The 29 listed entries are concerned with studies of vestibular function, optokinetic nystagmus, positional nystagmus, alcohol, determination of specific gravity, noise, p...
Alexander's law refers to the phenomenon in which the spontaneous nystagmus of a patient with a vestibular lesion is more intense when the patient looks in the quick-phase than in the slow-phase direction. Alexander's law was investigated in normal subjects as well as patients with vestibular lesions. During sinusoidal rotations of normal subjects, there was no trace of this ...
The integrity of the visual and vestibular systems is important in the maintenance of orientation during flight. Although alcohol is known to affect the vestibular system through the development of a positional alcohol nystagmus, information concerning th...
There are two forms of lateral semicircular canal benign paroxysmal positional vertigo: geotropic and apogeotropic. When the pathophysiological mechanism of the apogeotropic form is that of canalolithiasis, we can observe a transformation from an apogeotropic nystagmus into a geotropic one. Usually, this phenomenon happens simultaneously on both sides, thus enabling us to ...
... (Author). Descriptors : (*NYSTAGMUS, RESPONSE(BIOLOGY)), CATS, HUMANS, VESTIBULAR APPARATUS, STIMULATION(PHYSIOLOGY ...
In the human centrifuge an individual can be subjected simultaneously to ... Horizontal nystagmus was recorded on a Sanborn polygraph by means of the ...
NASA Website
... Page 4. NSAM - 917 SOME RELATIONSHIPS BETWEEN BLOOD ALCOHOL, POSITIONAL ALCOHOL NYSTAGMUS (PAN), ...
... Title : SOME RELATIONSHIPS BETWEEN BLOOD ALCOHOL, POSITIONAL ALCOHOL NYSTAGMUS (PAN), AND POSTURAL EQUILIBRIUM ...
... environment is influenced by many factors, of which ... as a factor of prime etiological significance (18). ... the neural signal from the canals was phase ...
... ROTATION), NYSTAGMUS, ADAPTATION(PHYSIOLOGY), PILOTS, STRESS(PHYSIOLOGY), EAR, PROPRIOCEPTION, SENSES(PHYSIOLOGY ...
A female infant with horizontal nystagmus and normal ophthalmic examination had isolated absence of the optic chiasm on magnetic resonance imaging. Eye movements were recorded on video and reviewed. Horizontal nystagmus without see-saw nystagmus was observed. Visual evoked potential showed inter-hemispheric asymmetry compatible with ...
