(1) abortifacient agents (43) prostaglandins (35) prostaglandins, synthetic (36) misoprostol (2 synthetic analog of natu- ral prostaglandin. Finally, the relationship between ,,misoprostol to the application in abortions: misoprostol is approved as an abortifacient in many countries, whereas (as stated

Dr. J. B. Thrersch in personal communication (1) indicated his animal research has reported dimethyl acetamide to be an effective abortifacient agent; monomethyl formamide to be a potent teratogenic agent without abortifacient properties; and dimethyl for...

The author discusses the validity of the claim that, in Antiquity, effective contraceptives and abortifacients were available, were widely used, and their use was responsible for the decline of population in certain periods. After reviewing the maneuvers and drugs used for those purposes, the author concludes that ancient physicians did not have at their disposal effective ...

Neosporosis is an infection of animals caused by an intracellular coccidian parasite, Neospora caninum, closely related to Toxoplasma gondii. The parasite is one of important abortifacient agents of bovine abortions worldwide. The aim of the study was to detect the prevalence of anti-Neospora antibodies in dairy aborting sheep from two eastern Slovak ...

1) Eric Blair (alias George Orwell) can rest easy in his grave, because birth control by governmentally imposed methods, such as incorporation of a contraceptive agent into drinking water, is totally unfeasible by 1984. 2) Fundamentally new birth control procedures in the female (for example, a once-a-month luteolytic or abortifacient ...

In reference to the presence of a list of abortifacients in a Greek manual of therapeutics or Arab origins (the Ephodia), the author reexamines the Oath of Hippocrates and its statement on abortion and abortifacients in the Hippocratic tradition as they were employed in Greek, Roman, Arab, and Byzantine cultures. PMID:17243320

Some indigenous plants reputedly possess antifertility properties when orally administered. Various extracts of some of these plants were used in an investigation to determine antifertility activity using a method which would ultimately detect anti-zygotic, blastocystoxic, anti-implantation or early abortifacient activity in adult female albino rats of proven fertility ...

Misoprostol (Cytotec) is safe and effective for induction of labor, although it is not approved by the Food and Drug Administration (FDA) for use in pregnancy. In August 2000, the manufacturer of misoprostol warned against its use in pregnancy because of its abortifacient properties and cited reports of maternal and fetal deaths when misoprostol was used to induce labor, ...

The objective of the present study was to determine the presence of recognised abortifacient viruses such as porcine reproductive and respiratory virus (PRRSV), Aujeszky's disease virus (ADV), porcine parvovirus (PPV) and porcine circovirus type 2 (PCV2), in tissues from aborted fetuses and stillborn neonates in cases of late reproductive failure in swine. A total of 293 ...

OBJECTIVES: This study explored reproductive health care in rural Washington State, reasons given by providers for not offering abortions, and providers' willingness to use medical abortifacients. METHODS: Physicians, midwives, nurse practitioners, and physician assistants in rural Washington completed an inventory of reproductive health services that they provide, whether and ...

The legal right to assert a conscientious objection is reviewed, using as an example the dispensing of abortifacient drugs by pharmacists. The three areas of law that most significantly concern the right to assert a conscientious refusal are employment law, conscience clauses, and religious discrimination law. Each of these is reviewed, with descriptions of recent cases. It is ...

Alcoholic extract of leaf and stem bark of A. excelsa at a dose of 250 mg equivalent of plant material/kg body weight, exhibited remarkably high anti-implantation and early abortifacient activities. The results are in agreement with the traditional use of this plant as a abortifacient by the Irula women of the Nilgiri district. PMID:8359839

The pharmacology, pharmacokinetics, clinical efficacy, contraindications and precautions, adverse effects, dosage, and cost of misoprostol are reviewed. Misoprostol is a synthetic analogue of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion and enhances mucosal resistance to injury. Misoprostol is extensively absorbed from the stomach and ...

Misoprostol, a synthetic analog of prostaglandin E1, is currently used in Chile and other countries as an antiulcer medication, mainly for the prevention of non-steroidal anti-infammatory-induced gastric ulcers. Due to its uterotonic properties, it is also indicated in obstetrics for induction of labor and termination of pregnancy. In this last case, misoprostol is either used alone or in ...

Human menopausal gonadotropin (hMG) is commonly used to induce ovarian follicular development and ovulation in infertile women. This report is a preliminary analysis of the ability of hMG to cause folliculogenesis and ovulation in pregnant laboratory animals. Wistar rats were injected subcutaneously with 0.5 mg of hMG on selected days of pregnancy. In addition, 2 days after receiving hMG, one ...

PEG modification (PEGylation) has been shown to reduce immunogenicity and prolong circulating half-life of proteins. In the present study, site-directed PEGylation was used to reduce immunogenicity and prolong plasma half-life of trichosanthin (TCS). Four TCS mutants, i.e. S7C, Q219C, K173C and [K173C,Q219C] (KQ), were constructed by site-directed mutagenesis. PEG modifications were done by ...

RU-486 or mifepristone developed by Roussel-UCLAF was approved in France in September 1988. Mifepristone coupled with a prostaglandin and administered within 49 days of the last menstrual period produces a complete abortion in about 95% of cases. A new regimen involves supplementing mifepristone with an oral prostaglandin, misoprostol. Mifepristone has been also reported to be effective as a ...

BackgroundThe epidemiological situation of ovine chlamydial infections in continental Europe, especially Germany is poorly characterised. Using the German state of Thuringia as a model example, the chlamydial sero- and antigen prevalence was estimated in thirty-two randomly selected sheep flocks with an average abortion rate lower than 1%. Seven vaccinated flocks were reviewed separately.ResultsA ...

During the 1800s, male physicians took over women's established sources of medical care and knowledge causing friction between women and their health matters and the rising medical profession. This conflict still exists today. Physicians provided little information on how to prevent pregnancy since to do so would interfere with their natural biologic function of motherhood. Reproduction no ...

ABSTRACTPurposeTo review the association of autism spectrum disorder (ASD) in individuals manifesting thalidomide embryopathy and M�bius sequence and compare them with three new studies in which ASD was also associated with ocular and systemic malformations: (1) a Swedish study of individuals with CHARGE association (Coloboma, Heart, choanal Atresia, developmental or growth Retardation, Genital ...

Lodgepole pine (Pinus contorta) and common juniper (Juniperus communis) contain high levels of isocupressic acid that has been identified as the abortifacient component of ponderosa pine needles in cattle. Therefore, the abortifacient potential of P contorta and J communis needles was tested in feeding trials with pregnant cattle. Cows (2 groups of 2 each) ...