Findings from the comparative study of the immunobiological properties of live brucellosis vaccines in guinea pigs are presented in the article. Vaccines from strains Brucella abortus 19 (U.S.) and 82 (Russia), in the S and SR forms, respectively, exhibited the highest and most pronounced immunological efficacy, ...

Intracutaneous immunization of guinea pigs with small doses (100,000 microbial cells) of live brucellosis vaccine from the Br. abortus No. 19 strain caused a more expressed immunization process than the subcutaneous immunization with the same doses, which...

The article presents the results from a study of two new vaccines against cattle brucellosis from Brucella abortus cultures. One of these is a live dry vaccine prepared from a weakly agglutinogenic strain in the SR form and the second, an inactivated adjuvant vaccine from an non-agglutinogenic ...

... Game through their Animal Care and Use Questionnaire. LITERATURE CITEDAdams, L. G. 1990. Development of live Brucella vaccines. Pages. 250�276. in L. G. ... ...

A bacteriophage-delivered DNA vaccine against Chlamydophila abortus was constructed by cloning a eukaryotic cassette containing the ompA gene (which expresses the Major Outer Membrane Protein) into a bacteriophage lambda vector. Four groups, each of 20 BALB/c mice were inoculated separately with the phage vaccine, a conventional DNA ...

The live attenuated Brucella abortus strain RB51 is a rifampin-resistant, lipopolysaccharide (LPS) O-chain-deficient mutant of virulent B. abortus 2308. The reduced O-chain content in RB51 prevents this bacterium from inducing antibodies detectable by the conventional serologic tests for bovine brucellosis diagnosis that mainly ...

The live attenuated Brucella abortus strain RB51 is a rifampin-resistant, lipopolysaccharide (LPS) O-chain-deficient mutant of virulent B. abortus 2308. The reduced O-chain content in RB51 prevents this bacterium from inducing antibodies detectable by the conventional serologic tests for bovine brucellosis diagnosis that mainly ...

During the first half of the 20th century, widespread regulatory efforts to control cattle brucellosis (Brucella abortus) in the Union of Soviet Socialist Republics were essentially nonexistent, and control was limited to selective test and slaughter of serologic agglutination reactors. By the 1950...

The effect of tetramisole (hydrochloride of racemic 2, 3, 5, 6,-tetrahydro-6-phenyl-imidazo [2, 1-b] thiazole) on immunization was investigated in mice vaccinated by killed Brucella melitensis cells suspended in incomplete adjuvant. Immunity to Brucella abortus challenge was estimated by the reduction in number of B. abortus colonies ...

Mouse protection tests were conducted with vaccines prepared from Brucella abortus or Listeria monocytogenes by means of x rays or formaldehyde. B. abortus (Buck 19 strain) was killed by irradiation with 50-kv x rays while suspended in saline solution. The absolute sterilizing dose for 10/sup 10/ bacteria was 1.5 Mr. ...

BackgroundPrevention and control of ovine enzootic abortion (OEA) can be achieved by application of a live vaccine. In this study, five sheep flocks with different vaccination and infection status were serologically tested using a competitive enzyme-linked immunosorbent assay (cELISA) specific for Chlamydophila (Cp.) ...

In this study a modified Komarov's bullet was developed to remotely deliver live brucellosis vaccines (Brucella abortus 82 and Brucella abortus 19). After modification, the bullet payload could carry the desired dose (10(11)CFU) of vaccine. As the bullet components were toxic to the ...

During the first half of the twentieth century, widespread regulatory efforts to control cattle brucellosis due to Brucella abortus in the Union of Soviet Socialist Republics were essentially non-existent, and control was limited to selective test and slaughter of serologic agglutination reactors. By the 1950s, 2-3 million cattle were being vaccinated ...

Vaccination against Brucella infections in animals is usually performed by administration of live attenuated smooth B. abortus strain S19 and B. melitensis strain Rev1. They are proven effective vaccines against B. abortus in cattle and against B. melitensis and B. ovis in sheep and goats, ...

Vaccination against Brucella infections in animals is usually performed by administration of live attenuated smooth B. abortus strain S19 and B. melitensis strain Rev1. They are proven effective vaccines against B. abortus in cattle and against B. melitensis and B. ovis in sheep and goats, ...

... Descriptors : *VACCINES, *BRUCELLA ABORTUS, *AGGLUTININS, BACTERIA, IMMUNE SERUMS, IMMUNITY, SERODIAGNOSIS, RABBITS. ...