Sep 9, 2011 ... The 3D Silicon Detector Telescope (TriTel) characterizes the radiation environment of the ISS and estimates the absorbed dose and dose ...
NASA Website
Accurate estimate of absorbed dose to target tumors and normal tissues in the body is an important requirement for establishing fundamental dose-response relationships for radioimmunotherapy. Two major obstacles have been the difficulty in obtaining an accurate patient-specific 3-D activity map ...
Energy Citations Database
Internal radiotherapy is currently focusing on beta emitters such as 90Y or 131I because of their high-energy emissions. However, conventional dosimetric methods (MIRD) are known to be limited for such applications. They are unable to take into account microscopic radionuclide distribution because standardized anthropomorphic phantoms are used, and absorbed ...
NASA Astrophysics Data System (ADS)
Implementation of polymer gel dosimetry in radiotherapy departments calls for: easily manufactured gel dosimeters of required physical-chemical properties, set-up procedures of irradiation, adaptation of three-dimensional scanning procedures and instruments as well as fast tool for calculation of 3D absorbed dose distribution in the polymer gel dosimeters ...
Accurate calculation of absorbed dose to target tumors and normal tissues in the body is an important requirement for establishing fundamental dose-response relationships for radioimmunotherapy. Two major obstacles have been the difficulty in obtaining an accurate patient-specific 3-D activity ...
131I radionuclide therapy studies have not shown a strong relationship between tumor absorbed dose and response, possibly due to inaccuracies in activity quantification and dose estimation. The goal of this work was to establish the accuracy of 131I activity quantification and ...
PubMed Central
The purpose of this study was to measure organ doses and the effective dose (ED) using a three-dimensional rotational X-ray (3D-RX) system and to determine the ED conversion factor from the dose area product (DAP) for skull, spine and biliary protocols. A commercial ...
PubMed
The main goal of this dissertation was to establish the feasibility of basing megavoltage external photon beam absorbed dose calculations in voxelized phantoms on SN deterministic calculations and pre-calculated electron absorbed dose kernels derived from full-physics Monte Carlo. The SN derived electron ...
OBJECTIVE: To estimate the absorbed organ dose and effective dose for a wide range of cone beam computed tomography scanners, using different exposure protocols and geometries. MATERIALS AND METHODS: Two Alderson Radiation Therapy anthropomorphic phantoms were loaded with LiF detectors (TLD-100 and TLD-100H) which were evenly ...
... Accession Number : AD0672563. Title : A CALORIMETER WITH INTERCHANGEABLE ABSORBERS FOR ABSORBED DOSE ...
DTIC Science & Technology
... Title : MODELS FOR ESTIMATING THE ABSORBED DOSE FROM ASSIMILATION OF RADIONUCLIDES IN BODY ORGANS OF HUMANS,. ...
Current methods for calculating the absorbed dose in a target region from a source region rely on a standard {open_quotes}reference man{close_quotes} geometry and assume an uniform distribution of radiolabel. While this approach is acceptable at the low levels of radioisotope administered for most diagnostic purposes, the generality of the calculations is ...
A general method is presented for patient-specific three-dimensional (3D) absorbed dose calculations based on quantitative SPECT activity measurements. The computational scheme includes a method for registration of the CT study to the SPECT image, and compensation for attenuation, scatter, and collimator-detector ...
A new method for the evaluation of radiotherapy 3D polymer gel dosimeters has been developed using ultrasound to assess the significant structural changes that occur following irradiation of the dosimeters. The ultrasonic parameters of acoustic speed of propagation, attenuation and transmitted signal intensity were measured as a function of ...
Gel dosimetry allows three-dimensional (3D) measurement of absorbed dose in tissue-equivalent dosemeter phantoms. Gel phantoms are imaged using optical techniques. In neutron capture therapy (NCT), properly designed gel dosemeters can give 3D dose ...
In this paper we focus exclusively on hole process. The motivation here is to investigate on the performance of EUVL for hole patterning in relation to contributions from mask, exposure tool, and resist process. For this purpose we use a waveguide simulation package that is capable of computing 3-D mask structure at very fast speed. We investigated the ...
The absorbed dose primary standard of the BEV is a graphite calorimeter. Two methods are employed for the conversion of absorbed dose to graphite into absorbed dose to water: calculation on the one hand and the use of an ionization chamber in combination ...
National Technical Information Service (NTIS)
The threshold values of total absorbed dose for causing changes in tensile properties of a polyetherimide film and the limitations of the absorbed dose rate for accelerated-exposure evaluation of the effects of electron radiation in geosynchronous orbit w...
Absorbed dose and dose equivalent from negatively and positively charged pions in energy range 10 to
NASA Technical Reports Server (NTRS)
... Title : A FORTRAN PROGRAM TO DETERMINE ABSORBED ORGAN DOSE DUE TO INHALATION OF RADIONUCLIDES,. ...
Aims: Skin doses have been an important factor in the dose prescription for breast radiotherapy. Recent advances in radiotherapy treatment techniques, such as intensity-modulated radiation therapy (IMRT) and new treatment schemes such as hypofractionated breast therapy have made the precise determination of the surface dose necessary. ...
... of absorbed dose; rem relates the absorbed dose in human tissue to the ... effort to increase the nation's preparedness for potential attacks against ...
... Title : Computational Determination of Absorbed Dose Distributions From Multiple Volumetric Gamma Ray Sources,. Corporate Author : ...
The concepts of radiation exposure dose, absorbed dose, and biological dose resulting from ionizing particles are reviewed. The units used in radiation measurements are defined, and the concept of electronic equilibrium is discussed. The Bragg-Gray cavity relation ls used to calculate the ...
In this paper we perform a fundamental study on the impact of mask absorber in ArF immersions lithography: the mask 3D effects. From simulations and analysis of diffraction coefficients we could identify a range of relevant features and imaging and placement phenomena. For these features, experimental results were obtained to pinpoint ...
INTRODUCTION: To assess an optimized 3D imaging protocol for intracranial nitinol stents in 3D C-arm flat detector imaging. For this purpose, an image quality simulation and an in vitro study was carried out. METHODS: Nitinol stents of various brands were placed inside an anthropomorphic head phantom, using iodine contrast. Experiments with objects were ...
... MINUTE INVESTIGATION OF ABSORBED DOSES IN COMPLEX ... DESCRIBED OF SUCH A DETERMINATION. ... CASE OF DOSE DISTRIBUTION AT ...
The objective of radiation therapy is to concentrate a prescribed radiation dose accurately within a target volume in the patient. Major advances in imaging technology have greatly improved our ability to plan radiation treatments in three dimensions (3D) and to verify the treatment geometrically, but there is a concomitant need to ...
The broad, long-term objectives of this application are to 1. develop easily implementable tools for radionuclide dosimetry that can be used to predict normal organ toxicity and tumor response in targeted radionuclide therapy; and 2. to apply these tools to the analysis of clinical trial data in order to demonstrate dose-response relationships for radionuclide therapy ...
DOE Information Bridge
A dual modality SPECT-CT prototype dedicated to uncompressed breast imaging (mammotomography) has been developed. The CT subsystem incorporates an ultra-thick K-edge filtration technique producing a quasi-monochromatic x-ray cone beam to optimize the dose efficiency for uncompressed breast tomography. We characterize the absorbed dose ...
EUVL requires the use of reflective optics including a reflective mask. The mask contains a reflecting multilayer, tuned for 13.5 nm light, and an absorber which defines the dark areas. The EUV mask itself is a complex optical element with many more parameters than just the mask CD uniformity of the patterned features that impact the final wafer CDU. One of these parameters is ...
Medical Internal Radiation Dose(MIRD) schema was developed for calculating the absorbed dose from the administrated radiopharmaceuticals. With the biological distribution data and physical properties of the radionuclide, we can estimated the absorbed dose...
... Abstract : The effects of electron radiation on Ultem, a ... were studied for total absorbed doses from 1.0 kGy to 100 MGy at absorbed dose rates from ...
The biological effect of radioimmunotherapy (RIT) is most commonly assessed in terms of the absorbed radiation dose. In tumor, conventional dosimetry methods assume a uniform radionuclide and calculate a mean dose throughout the tumor. However, the vasculature of solid tumors tends to be highly irregular and the systemic delivery of ...
Abstract Background. Clinical treatment with radionuclides is usually preceded by biokinetic and dosimetry studies in small animals. Evaluation of the therapeutic efficacy is essential and must rely on accurate dosimetry, which in turn must be based on a realistic geometrical model that properly describes the transport of radiation. It is also important to include the source distribution in the ...
... Abstract : ;Contents: Interaction between radiation and tissue; Radiation quantities and units; Radiation quality and dose equivalent; History of dose ...
... EQUIVALENTS OF GALACTIC RADIATION EXPOSURE IN SPACE,. ... In assessing the astronaut's exposure from galactic ... of absorbed doses to dose ...
... AS INDICATORS OF ABSORBED RADIATION DOSE IN RATS. ... of doses of mixed gamma-neutron radiations or 14 ... was a function of dose over the ...
The DPM (Dose Planning Method) Monte Carlo electron and photon transport program, designed for fast computation of radiation absorbed dose in external beam radiotherapy, has been adapted to the calculation of absorbed dose in patient-specific internal emitter therapy. Because both its photon ...
To understand tumor response and normal organ toxicity following internal emitter therapy a succinct yet adequate representation of the spatial dose distribution within the target is necessary. Using 3D-ID, a software package that implements a patient-specific, three-dimensional approach to dosimetry, we obtain the mean and a ...
Highly conformal dose distributions can be created by the superposition of many radiation fields from different directions, each with its intensity spatially modulated by the method known as tomotherapy. At the planning stage, the intensity of radiation of each beam element (or bixel) is determined by working out the effect of superposing the radiation through all bixels with ...
The Boltzmann equation for the transport of pencil beams of light ions in semi-infinite uniform media has been calculated. The equation is solved for the practically important generalized 3D case of Gaussian incident primary light ion beams of arbitrary mean square radius, mean square angular spread, and covariance. The transport of the associated ...
This paper discusses the 3D dosimetric consequences of radiotherapy delivery during two kinds of motion, (i) the respiratory motion by the patient and (ii) the motion by the gantry while rotating around the patient. Respiratory motion primarily compromises treatments in the thorax and abdomen regions. Several strategies to reduce respiratory motion effects have been developed or are under ...
A novel design of an optical tomographic scanner is described that can be used for 3D mapping of optical attenuation coefficient within translucent cylindrical objects with spatial resolution on the order of 100 microns. Our scanner design utilizes the cylindrical geometry of the imaged object to obtain the desired paths of the scanning light rays. A rotating mirror and a photodetector are placed ...
Patient-specific 3-dimensional radiobiologic dosimetry (3D-RD) was used for (131)I treatment planning for an 11-y-old girl with differentiated papillary thyroid cancer, heavy lung involvement, and cerebral metastases. (124)I PET was used for pharmacokinetics. Calculation of the recommended administered activity, based on lung toxicity constraints, was ...
Patient-specific 3-dimensional radiobiologic dosimetry (3D-RD) was used for 131I treatment planning for an 11-y-old girl with differentiated papillary thyroid cancer, heavy lung involvement, and cerebral metastases. 124I PET was used for pharmacokinetics. Calculation of the recommended administered activity, ...
... Title : Radiation Energy Absorbed by Human Phantoms ... DOSIMETERS, INSTRUMENTATION, IONIZATION CHAMBERS, DOSE RATE, RADIATION ...
The macro Monte Carlo (MMC) method has been developed to improve the speed of traditional Monte Carlo (MC) high-energy electron transport calculations without loss in accuracy. The MMC algorithm uses results derived from conventional MC simulations of electron transport through macroscopic spheres of various radii and consisting of a variety of media. Based on these results, electrons are ...
This report describes methods and computer programs for calculating absorbed-dose distribution in a water target irradiated by proton beams. The spatial pattern of absorbed dose from monoenergetic pencil beams is calculated as a function of the depth in t...
Values of the fast neutron absorbed dose rate in an ethylene absorber are given as a function of penetration distance in hydrogen. The dose rates were obtained by numerical integration of the product of the differential number spectrum and the ethylene conversion factors. (auth)
The conversion of absorbed doses in graphite to absorbed doses in water was studied. A method employing a thin walled ionization chamber as a transfer device was developed. A commercial secondary standard therapy level exposure meter was used in one of th...
At present, absorbed dose calculations for radionuclides in the human circulatory system used relatively simple models and are restricted in their applications. To determine absorbed doses to the blood and to the surface of the blood vessel wall, EGS4 Mon...
Irradiation of trabecular bone regions is an important area within internal dosimetry considering the role these bone sites play in both the skeletal and hematopoietic systems. Since bone marrow is located within trabecular bone regions, radiation incident upon bone is likely to also cause damage to the marrow. Radionuclides that localize in bone, especially charged-particle emitters, have the ...
A technique is presented for calculating the dose or energy absorbed in a material from a knowledge of the ..gamma.. radiation field and the composition of the material. The absorbed dose per unit exposure for various elements and the absorbed dose as a function of material ...
The need for fast, accurate and high resolution dosimetric quality assurance in radiation therapy has been outpacing the development of new and improved 2D and 3D dosimetry techniques. This paper summarizes the efforts to create a novel and potentially very fast, 3D dosimetry method based on the observation of scintillation light from an irradiated liquid ...
... dose, Q is the quality factor, and N is the product of any other modifying factors such as those accounting for effects due to dose rate, dose ...
Apr 21, 2011 ... Data Set Name, Crew Absorbed Doses from Passive Dosimeters ... This table shows a comparison of absorbed doses from TLD passive dosimeters. ...
... dosimeters for X rays in the 1�50 MeV range be calibrated in terms of absorbed dose to ... ...
NBII National Biological Information Infrastructure
Read out the absorbance of a dosimetric foil is accomplished by two beam spectrophotometer. Such a solution makes possible the compensation of light source instabilities and ensures higher stability of the dose reader. The error of absorbance measurement ...
... In dosimetry, the absorbed dose is defined as the amount of energy absorbed per unit mass of the material. ... 10 Protons 10 Alpha particles 10 ...
... on a cellular level using tissue-equivalent scintillation techniques ... first phase of the development of a Cellular Absorbed Dose Spectrometer (CADS ...
Four tables designed to permit rapid conversion from one to another of the units for absorbed dose, absorbed dose rate, energy, and power are given. (M.C.G.)
... Accession Number : ADD344981. Title : Computational Determination of Absorbed Dose Distribution From Gamma Ray Sources,. Corporate Author ...
The objective of this paper is to critically evaluate the interrelationship of the radiopharmaceuticals, radionuclides and organ visualization instrumentation on the resultant absorbed dose to a patient having a bone scan versus the clinical information o...
... for the proton events studied here. Descriptors : *IRRADIATION, *SOLAR FLARES, *DOSIMETRY, DISTRIBUTION, PROTONS, DEPTH, SURFACES ...
... Abstract : With the development of computer controlled MLC, IMRT now provides unprecedented means to deliver 3D-dose distributions with sub ...
Administration of x-ray contrast agents during heart catheterization examination increases the absorbed radiation dose in tissue. To estimate the dose absorbed by the blood of children undergoing diagnostic heart catheterization and angiocardiography, a number of measurements and calculations were conducted ...
Polymer gel dosimeters are fabricated from radiation sensitive chemicals which, upon irradiation, polymerize as a function of the absorbed radiation dose. These gel dosimeters, with the capacity to uniquely record the radiation dose distribution in three-dimensions (3D), have specific ...
Determination of absorbed dose in biological targets after high LET ? particules irradiation needs heavy calculations. A softwave has been developed in order to allow everyone to calculate hit probability and absorbed dose. It is particularly adapted to the study of cell cultures irradiated with electrodeposited ...
The dermal absorption, systemic elimination, and dermal wash efficiency for polychlorinated biphenyls (PCBs) were determined. /sup 14/C-labeled 42% PCB and /sup 14/C-labeled 54% PCB were topically and parenterally administered to rhesus monkeys and guinea pigs. Dermal absorption, determined by /sup 14/C urinary excretion, was extensive. In guinea pigs, 33% of the applied /sup 14/C-labeled 42% PCB ...
... necessary for absorbed radiation dose estimates, as ... SUBSTANCES, *RADIOACTIVE ISOTOPES, *RADIATION DOSAGE, *DIAGNOSTIC AGENTS ...
... Additional work is required relating resistance change for these materials to absorbed ribbon dose, and determination of the maximum dose for ...
nonuniform dose distributions resulting from flare proton spectra leads to the assignment of the absorbed dose at 4- ...
