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1
Polymeric hydrogels for novel contact lens-based ophthalmic drug delivery systems: a review.
2007-10-25

Only about 5% of drugs administrated by eye drops are bioavailable, and currently eye drops account for more than 90% of all ophthalmic formulations. The bioavailability of ophthalmic drugs can be improved by a soft contact lens-based ophthalmic drug delivery system. Several polymeric hydrogels have been investigated for soft contact ...

PubMed

2
Biopolymer-based hydrogels as scaffolds for tissue engineering applications: a review.
2011-03-30

Hydrogels are physically or chemically cross-linked polymer networks that are able to absorb large amounts of water. They can be classified into different categories depending on various parameters including the preparation method, the charge, and the mechanical and structural characteristics. The present review aims to give an overview of ...

PubMed

3
Synthesis and properties of waterborne polyurethane hydrogels for wound healing dressings.
2008-05-01

To accomplish ideal wound healing dressing, a series of waterborne polyurethane (WBPU) hydrogels based on polyethylene glycol (PEG) were synthesized by polyaddition reaction in an emulsion system. The stable WBPU hydrogels which have remaining weight of above 85% were obtained. The effect of the soft segment (PEG) content on water ...

PubMed

4
Novel Crosslinked Graft Copolymer of Methacrylic Acid and Collagen as a Protein-Based Superabsorbent Hydrogel with Salt and Ph-Responsiveness Properties
2008-08-01

In this paper, a novel protein-based superabsorbent hydrogel was synthesized through crosslinking graft copolymerization of methacrylic acid (MAA) onto collagen, using ammonium persulfate (APS) as a free radical initiator in the presence of methylenebisacrylamide (MBA) as a crosslinker. The hydrogel structure was confirmed using FTIR ...

NASA Astrophysics Data System (ADS)

5
Pseudopolyrotaxanes (PPRs) on Inorganic Nanoplatelets and their Supramolecular hydrogels.
2011-09-01

In this paper, we demonstrate the first hybrid suprastructure of pseudopolyrotaxanes (PPRs) on clay nanoplatelets. Simple end-modification of poly(ethylene glycol) with pyridinium (PEG-N+) enabled the chains to form brush-like conformation on clay surfaces. Thus the PEG chains were able to thread into the cavities of ?-cyclodextrins (?-CDs) leading to hybrid PPR hydrogels. ...

PubMed

6
Polysaccharides and cellulose in the design of wound healing materials

1. Chronic Wound Dressings that Sequester Harmful Proteases: Traditionally the use of carbohydrate-based wound dressings including cotton, xerogels, charcoal cloth, alginates, chitosan and hydrogels, have afforded properties such as absorbency, ease of application and removal, bacterial protection, ...

Technology Transfer Automated Retrieval System (TEKTRAN)

7
Polysaccharides and Cellulose in the Design of Wound Healing Materials

Chronic Wound Dressings that Sequester Harmful Proteases: Traditionally the use of carbohydrate-based wound dressings including cotton, xerogels, charcoal cloth, alginates, chitosan and hydrogels, have afforded properties such as absorbency, ease of application and removal, bacterial protection, flu...

Technology Transfer Automated Retrieval System (TEKTRAN)

8
Novel Biomaterials Methodology, Development and Application

Traditionally the use of carbohydrate-based wound dressings including cotton, xerogels, charcoal cloth, alginates, chitosan and hydrogels, have afforded properties such as absorbency, ease of application and removal, bacterial protection, fluid balance, occlusion, and elasticity. Recent efforts in ...

Technology Transfer Automated Retrieval System (TEKTRAN)

9
Synthesis and swelling behavior of Protein-g-poly Methacrylic acid/kaolin superabsorbent hydrogel composites
2008-08-01

A novel superabsorbent hydrogel composite based on Collagen have been prepared via graft copolymerization of Methacrylic acid (MAA) in the presence of kaolin powder using methylenebisacrylamide (MBA) as a crosslinking agent and ammonium persulfate (APS) as an initiator. The composite structure was confirmed using FTIR spectroscopy. A new absorption band at ...

NASA Astrophysics Data System (ADS)

10
Biomedical application of a superabsorbent hydrogel for body water elimination in the treatment of edemas.
2003-12-01

A novel system of body water elimination to be used for the treatment of edemas, based on superabsorbent cellulose derivatives able to absorb large amounts of water and water solutions, has been investigated. Hydrogels have been synthesized starting from water solutions of carboxymethylcellulose sodium salt and hydroxyethylcellulose, ...

PubMed

11
Tunable microlens arrays actuated by various thermo-responsive hydrogel structures
2010-11-01

We report on liquid-based tunable-focus microlens arrays made of a flexible polydimethylsiloxane (PDMS) polymer. Each microlens in the array is formed through an immiscible liquid-liquid interfacial meniscus. Here deionized water and silicone oil were used. The liquids were constrained in the PDMS structures fabricated through liquid-phase photopolymerization for molding and ...

NASA Astrophysics Data System (ADS)

12
Aromatic organic contaminant removal from an aqueous environment by p(4-VP)-based materials.
2011-07-15

p(4-vinylpyridine) (p(4-VP)) hydrogels were prepared in bulk (macro, 5�6mm) and in nanosizes (370nm) dimensions. The prepared hydrogels were used to remove organic aromatic contaminates such as 4-nitrophenol (4-NP), 2-nitrophenol (2-NP), phenol (Ph) and nitrobenzene (NB) from an aqueous environment. Important parameters affecting the absorption ...

PubMed

13
Controlled drug release from biodegradable thermoresponsive physical hydrogel nanofibers.
2010-01-11

Hydrogel nanofiber mats based on thermoresponsive multiblock poly(ester urethane)s comprising poly(ethylene glycol) (PEG), poly(propylene glycol) (PPG), and poly(epsilon-caprolactone) (PCL) segments were fabricated by electrospinning. The hydrogel nanofiber mats were more water absorbent under cold conditions and ...

PubMed

14
Reversible Polymer Hydrogels
2008-12-01

... Temperature sensitive hydrogels based on N-isopropyl acrylamide (NIPA) and acryloyl glucosamine (AG) were synthesized using ammonium ...

DTIC Science & Technology

15
Reversible Polymer Hydrogels
2008-12-01

... Abstract : Temperature sensitive hydrogels based on N-isopropyl acrylamide (NIPA) and acryloyl glucosamine (AG) were synthesized using ...

DTIC Science & Technology

16
Unexpected factors influencing water absorbency of certain ...
1974-09-01

... EARLIER. Now several new factors have been discovered that influence the water absorptive capacity of these hydrogel films. ...

DTIC Science & Technology

17
Thermoreversible hydrogel scaffolds for articular cartilage engineering

Thermoreversible hydrogel scaffolds for articular cartilage engineering John P. Fisher,1 hydrophilic proteogly- cans, an engineered cartilage graft may be based on syn- thetic hydrogels to mimic 35�C, allowing an aqueous solution containing cells at room temperature to form a hydrogel

E-print Network

18
ENZYMATIC AND NON-ENZYMATIC PATHWAYS TO FORMATION OF DOPA-MODIFIED PEG HYDROGELS

of these processes are not fully understood, it is believed that the unoxidized catechol form of DOPA is responsible.7 The model catechol of diDOPA has absorbance peaks with max of 268 and 420 nm at pH 3 and 274 weight polymers cross-linked from catechol amines.9 Based on the observed intermediates, melanogenesis

E-print Network

19
Water absorbency studies of ?-radiation crosslinked poly(acrylamide-co-2,3-dihydroxybutanedioic acid) hydrogels
2004-10-01

Water absorbency behavior of acrylamide (AAm)/2,3-dihydroxybutanedioic acid (DBA) hydrogels synthesized by ?-radiation crosslinking of AAm and DBA in an aqueous solution was investigated. Different amounts of DBA containing AAm/DBA hydrogels were obtained in the form of rods via a radiation technique. Swelling experiments were ...

NASA Astrophysics Data System (ADS)

20
Rheological properties of peptide-based hydrogels for biomedical and other applications�
2010-04-26

Peptide-based hydrogels are an important class of biomaterials finding use in food industry and potential use in tissue engineering, drug delivery and microfluidics. A primary experimental method to explore the physical properties of these hydrogels is rheology. A fundamental understanding of peptide hydrogel ...

PubMed Central

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21
Glucose-Responsive Hydrogels Nicholas A. Peppas

Glucose-Responsive Hydrogels Nicholas A. Peppas Christie D. Bures Departments of Chemical.S.A. INTRODUCTION Hydrogels are hydrophilic polymer networks that can absorb large amounts of water, but remain insoluble because of the presence of cross-links, entanglements, or crystalline regions.[1] Hydrogels often

E-print Network

22
Amperometric Biosensors Based on 3-Dimensional Hydrogel ...
1993-05-24

... Accession Number : ADA265528. Title : Amperometric Biosensors Based on 3-Dimensional Hydrogel-Forming Epoxy Networks. ...

DTIC Science & Technology

23
Photo- and electropatterning of hydrogel-encapsulated living cell arrays Dirk R. Albrecht,a

Photo- and electropatterning of hydrogel-encapsulated living cell arrays Dirk R. Albrecht,a Valerie)-based hydrogel to create a local 3-D microenvironment. First, `photopatterning' selectively crosslinks hydrogel, represents an important step toward cell-based assays that accurately predict in ...

E-print Network

24
Swelling equilibria for cationic 2-hydroxyethyl methacrylate (HEMA)-based hydrogels.
1993-01-01

Cationic HEMA-based hydrogels were synthesized by copolymerizing HEMA with ((methacrylamido)propyl)trimethylammonium chloride (MAPTAC). Swelling equilibria were measured in pure water an in aqueous sodium chloride solutions. Hydrogel swelling is an increa...

National Technical Information Service (NTIS)

25
Cationic hydrogels for toxic arsenate removal from aqueous environment.
2007-06-21

Poly(3-acrylamidopropyl)trimethylammonium chloride (p(APTMACl)) hydrogels were synthesized and utilized as absorbents for the removal of toxic arsenate from aqueous medium. The pH-dependent swelling characteristics of the hydrogel were studied, and the experimental parameters that affect the absorption efficiency were investigated. Our ...

PubMed

26
Chitosan-based hydrogels for controlled, localized drug delivery.
2009-09-30

Hydrogels are high-water content materials prepared from cross-linked polymers that are able to provide sustained, local delivery of a variety of therapeutic agents. Use of the natural polymer, chitosan, as the scaffold material in hydrogels has been highly pursued thanks to the polymer's biocompatibility, low toxicity, and biodegradability. The advanced ...

PubMed

27
Response of intestinal cells and macrophages to an orally administered cellulose-PEG based polymer as a potential treatment for intractable edemas.
2005-07-01

The elimination of water from the body represents a fundamental therapeutic goal in those diseases in which oedemas occur. Aim of this work is the design of a material able to absorb large amount of water to be used, by oral administration, in those cases in which resistance to diuretics appears. Sorption and mechanical properties of the cellulose based ...

PubMed

28
Multiple Strategy Bio-Detection Sensor Platforms Made From ...
2006-01-31

... Many hydrogel materials are commercially available. Currently our focus is on an alginate based hydrogel because an ...

DTIC Science & Technology

29
Hydrogen Peroxide Electrodes Based on Electrical ...
1994-02-16

... dimensional redox epoxy hydrogel on a current collector. In the case of HRP we ... The redox hydrogel was made of a poly(4-vinyl pyridine) backbone ...

DTIC Science & Technology

30
Optimization of Low Temperature Vitrification for Surface Analysis of Hydrated Hydrogel Polymers.
1994-01-01

A method for analyzing hydrated hydrogel polymer surfaces in ultra-high vacuum atmospheres has been developed. The materials used for this study were commercially available poly(2-hydroxyethylmethacrylate) (HEMA) based hydrogel polymer (soft) contact lens...

National Technical Information Service (NTIS)

31
From lifting to planting: Root dip treatments affect survival of loblolly pine (Pinus taeda)

Hydrogels and clay slurries are the materials most commonly applied to roots of pines in the southern ... were tested: kaolin clay, two grades of polyacrylamide hydrogels, and a cornstarch-based hydrogel. In ...

NBII National Biological Information Infrastructure

32
General and Plastic Surgery Devices Panel - May 8, 2000

... in a non-polymerized form and chemically and photo-polymerized on the lung tissue into an absorbable hydrogel polymer that is intended to seal air leaks over ...

Center for Biologics Evaluation and Research (CBER)

33
Preparation of Porous Alumina Fibres by Unidirectional ...

... Abstract : This letter reports on the preparation of alumina fibres based on unidirectional freezing of an alumina hydrogel. ...

DTIC Science & Technology

34
Preparation of Porous Alumina Fibres by Unidirectional ...
1986-01-01

... Abstract : This letter reports on the preparation of alumina fibers based on unidirectional freezing of an alumina hydrogel. ...

DTIC Science & Technology

35
Developing Nanostructured Polymer Gels for Chemical and ...
2005-08-10

... Biodegradable hydrogel nanoparticles based on FDA approved biopolymers have been synthesized. The biocompatibility ...

DTIC Science & Technology

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