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1
Neuromyelitis Optica

... rare neurological syndromes such as NMO. NIH Patient Recruitment for Neuromyelitis Optica Clinical Trials At NIH Clinical ...

MedlinePLUS

2
Neuromyelitis optica in a young child with positive serum autoantibody
2008-09-01

Relapsing neuromyelitis optica is rare in children. The identification of highly specific serum autoantibody marker (neuromyelitis optica �immunoglobulin G) differentiates neuromyelitis optica from other demyelinating disorders particularly in clinically challenging cases. We present a child with multiple episodes of transverse ...

PubMed Central

3
A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic�s Disease)
2006-11-27

Neuromyelitis Optica; Myelitis, Transverse; Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System

ClinicalTrials.gov

4
Hesperides Microbiological Campaign: collection of genetic - NASA

entre Microorganismos Antarticos LA FUENTE: Buque Investigacion Oceanographica Hesperides ... disuelto, fluorescencia y transmision de luz. Procesado de ...

NASA Website

5
Geological evolution of the Pacific margin of Western Antarctica ...

(fluorescencia) de las aguas superficiales con termosalinometro y fluorometro, y registro cont?nuo de datos meteorologicos. Ademas, aprovechando los borneos ...

NASA Website

6
Antarctic Master Directory

Combinamos las medidas de intercambio de gases con analisis de fluorescencia en clorofila, con observaciones anatomicas y ultra estructurales, ...

NASA Website

7
Transverse Myelitis Association

The organization advocating for children, adolescents, and adults with the spectrum disorders of acute disseminated encephalomyelitis, neuromyelitis optica, ...

MedlinePLUS

8
Biobank For MS And Other Demyelinating Diseases
2010-03-10

Multiple Sclerosis; Transverse Myelitis; Neuromyelitis Optica; Acute Disseminated Encephalomyelitis; Optic Neuritis

ClinicalTrials.gov

9
Relapse of Neuromyelitis Optica Spectrum Disorder Associated with Intravenous Lidocaine
2011-05-11

Lidocaine unmasks silent symptoms and eases neuropathic pain in multiple sclerosis patients; however, the effects of lidocaine in neuromyelitis optica have never been reported. We describe the case of a 59-year-old Japanese woman with neuromyelitis optica spectrum disorder who developed optic neuritis 1 day after intravenous lidocaine injection for ...

PubMed Central

10
Efficacy and safety of rituximab in pediatric neuromyelitis optica.
2010-12-23

Neuromyelitis optica is a central nervous system disease characterized by optic neuritis and transverse myelitis. It is a devastating illness, and early treatment may prevent future relapses and severe disability. However, there is much variability in protocols used for treatment. In limited studies, rituximab has shown efficacy in adult neuromyelitis ...

PubMed

11
The Detection, Removal and Effect on Damage Thresholds of ...

... Abstract : We describe the detection, by resonance ionization mass spectrometry (RIMS), of cerium impurities on fused silica optica substrates. ...

DTIC Science & Technology

12
De Rol Van De Geintegreerde Optica In De Optische ...
1989-09-01

... Integrated optics developed simultaneously with these developments. Integrated optics is a branch of optics which tries ...

DTIC Science & Technology

13
Rayos X de la Tierra - Ciencia - Ciencia @ NASA

13 Oct 2010 ... Cada pocos segundos hay un peque?o resplandor de radiaci?n X causada por este proceso, llamado "fluorescencia". La luna tambi?n centellea, ...

NASA Website

14
Direccion Nacional Del Antartico GCMD Portal - GCMD - NASA

FASE 1: NAVEGACION USHUAIA-LIVINGSTON Se han medido en continuo las corrientes ADCP y sondeos CTD en (salinidad, temperatura, fluorescencia, profundidad, ...

NASA Website

15
[Primary Sj�gren's syndrome and neuromyelitis optica].
2010-09-01

Neuromyelitis optica (NMO) is characterized by the association of optic neuritis and myelitis without any other neurological signs. In 30�% of the cases, NMO is associated with a systemic disorders. We report two cases of NMO associated with primary Sj�gren's syndrome that was diagnosed during an acute flare of NMO. The relationship between NMO and Sj�gren's syndrome has ...

PubMed

16
Software Tools Streamline Project Management - NASA

May 1, 2011 ... PanOptica software incorporates three NASA-developed programs. ... International Space Station Knowledge Management; Mishap and ...

NASA Website

17
Optically Transparent Magnesium Oxide
1973-12-21

... OPTICA L TARENT MAGNESIUM OXIDE ... oxide polyerystalline body by hot pressirw a powdered mixture of 3tthium fluoride and magnesium oxide. ...

DTIC Science & Technology

18
FINAL TECHNICAL REPORT NUMERICAL STUDIES OF COLJAPSING ...

models with the semi-empirical temperature of Taraf i ar et al. that the dependence of~temperature on density and optica 9 depth is in ...

NASA Website

19
Design and Construction of a Medium Resolving, Power ...
1999-12-01

... was done with two commercially available optical design software packages, OSLO LT by Sinclair Optics, Inc., and Optica by Wolfram Research, Inc ...

DTIC Science & Technology

20
An Integrated Optical System for Synoptic Remote Sensing ...

The described DOLPHIN (Diving OpticaL Profiler and High-speed Integration ... The DOLPHIN will have immediate commercial applications in remote sensing ...

NASA Website

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21
AM and FM Modulation of a Helium-Neon Laser Beam Using ...
1972-12-01

... Accession Number : AD0757672. Title : AM and FM Modulation of a Helium-Neon Laser Beam Using Acousto-Optica; Interaction. ...

DTIC Science & Technology

22
Neuromyelitis optica: brain abnormalities in a Brazilian cohort.
2008-03-01

Neuromyelitis optica (NMO) is a demyelinating disease consisting of relapsing-remitting optic neuritis and myelitis with a more severe course than Multiple Sclerosis. Recently, it has been shown that almost 50% of patients with NMO can have brain magnetic resonance imaging (MRI) abnormalities. We report on six Brazilian patients with NMO, fulfilling the 1999 Wingerchuck ...

PubMed

23
Neuromyelitis optica.
2008-01-01

Neuromyelitis optica (NMO) is an uncommon central nervous system demyelinating disease that produces transverse myelitis and optic neuritis. Although commonly misdiagnosed as multiple sclerosis, a number of features can help differentiate the two entities, including the presence of NMO-IgG. Immunosuppressants are used to treat NMO, but the overall prognosis is poor. ...

PubMed

24
Hypocretinergic dysfunction in neuromyelitis optica with coma-like episodes
2009-02-02

Devic�s neuromyelitis optica (NMO) is a severe demyelinating disease of the central nervous system, often misdiagnosed as multiple sclerosis, and involving mainly optic nerves and the spinal cord. We report on a peculiar case of relapsing NMO with severe recurrent dysautonomia and hypersomnia, in which we had the opportunity to observe a dramatic decrease in ...

PubMed Central

25
Aquaporin-4 antibody positive neuromyelitis optica with syndrome of inappropriate antidiuretic hormone secretion.
2011-01-01

Neuromyelitis optica (NMO) has been reported to be associated with endocrinopathies, such as amenorrhea, galactorrhea, and diabetes mellitus. However, its association with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is extremely rare. We herein report an adult case of NMO with SIADH in a female Chinese patient. The patient was aquaporin-4 antibody ...

PubMed

26
Microcantidades de hafnio en circonio en filmes delgados por fluorescencia de Rayos X. (X-ray fluorescence of microquantities of hafnium in zirconium by precipitation as thin film).
1988-01-01

The importance of Zr and Hf in the nuclear industry represents and increasing need for the development of reliable chemical methods to determine Hf traces in Zr matrix. A precipitation method in amoniacal medium was developed. A thin film is obtained wher...

National Technical Information Service (NTIS)

27
Determinacion de Vanadio y Titanio en aceites utilizando curvas de calibracion acuosas por fluorescencia de rayos X. (Determination of Vanadium and Titanium in oil using aqueous calibration curves by X-ray fluorescence).
1989-01-01

It is shown that the determination of minor elements in oil can be realized with high accuracy and precision using standard aqueous solutions. The relationship Ii/(Ia-Io)=KCi must be used, where Ii concentration Ci, Ia is the intensity of the scattered ra...

National Technical Information Service (NTIS)

28
Determinacao de torio em solucoes simuladas do processo thorex por espectrometria de fluorescencia de raios-X. (Thorium determination by x-ray fluorescence spectrometry in simulated thorex process solutions).
1991-01-01

The X-ray fluorescence method for thorium determination in aqueous and organic (TBP/n-dodecane) solutions is described. The thin film technique for sample preparation and a suitable internal standard had been used. The best conditions for Thorium determin...

National Technical Information Service (NTIS)

29
Comparacao entre as tecnicas de espectrometria por fluorescencia de raios-X e ICP para analise de altas ligas no estado solido. (Comparison between the X-ray fluorescence technique and inductive coupling plasma for the analysis of high alloys in solid state).
1989-01-01

The benefits of the Solid Sampling ICP (55 ICP) technique for the analysis of high alloys are presented and some facts of this new technique are discussed. The global calibration of nickel base alloys is used to illustrate the powerful capability of this ...

National Technical Information Service (NTIS)

30
Caracterizacao de ligas de monel pela tecnica de fluorescencia de raios-X. (Characterization of monel alloys by X-ray fluorescence technique).
1989-01-01

Method for the determination of Ni, Cu, Fe, Mn, Si, Al, Ti, Co, Cr and Mo in Monel alloys using thin film for sample preparation and X-ray fluorescence techniques is described. Samples in filings form were completely dissolved with inorganic acids and the...

National Technical Information Service (NTIS)

31
Neuromyelitis optica - an update: 2007�2009

Neuromyelitis optica is an inflammatory demyelinating disorder of the central nervous system. The discovery of a specific antibody (NMO IgG /aquaporin-4 antibody) in patients with this condition has led to a marked revival of research on the disease. This article summarizes the major advances in neuromyelitis optica, particularly in the last 2 years, and ...

PubMed Central

32
view--This is a image map of the video rack system. click on a ...

ODR--Panasonic Optical Disc Recorder. ODP--Panasonic Optica Disc Player. VCR-- Panasonic Video Cassette Recorder. Small Monitors--8" Sony Video Monitors ...

NASA Website

33
Vertical Ozone Distribution During Maximum and Minimum Solar Activity.
1989-01-01

To study the latitude variation of ozone vertical distribution the complex experiment was carried out in February to July 1985 between 40 deg N to 70 deg S at the Pacific and the Indian Oceans. The great bulk of their data network were taken by the optica...

National Technical Information Service (NTIS)

34
Time-Resolved and Spectroscopic Three-Dimensional Optical Breast Tomography.
2008-01-01

The research carried out during the current reporting period included: (a) application and further refinement of optical tomographic imaging using independent component analysis (OPTICA) developed during the earlier reporting periods for locating and cros...

National Technical Information Service (NTIS)

35
The Application of Signal Detection Theory to Optics PROGRESS ...

Fellgett and E. H. Linfoot, Phil. Trans. Roy. Soc. (London), x, no. A. 931, 369- 407 (February 17, ... E. H. Linfoot, Optica Acta 2, 1-14 (March-June, 1958). ...

NASA Website

36
Tabernero and Ahumada, 1992 OSA Annual Meeting - NASA Vision Group

Development of a translation-invariant image representation. Antonio Tabernero Instituto de Optica, Serrano 121. Madrid 28006, Spain. Albert J. Ahumada Jr. ...

NASA Website

37
TICAL.DATA STORAGE CENTER - NASA Technical Report Server (NTRS)

Dielectric Lamellar Diffraction Grating," Optica Acta 28, 413-428 (1981). M. Neviere, "The Homogeneous. Problem," in Electromagnetic. Theory of Gratings, ...

NASA Website

38
Stress-Optical Behavior of Polymethylene and Poly(Dimethylsiloxane).
1972-01-01

The strain birefringence of polymethylene (PM) and for poly(dimethylsiloxane) (PDMS) networks, unswollen and swollen with diluents, has been investigated over the temperature ranges 115-220C and 15-90C, respectively. Temperature coefficients of the optica...

National Technical Information Service (NTIS)

39
Some Activities of MISSE 6 Mission.
2009-01-01

The objective of the Materials International Space Station Experiment (MISSE) is to study the performance of novel materials when subjected to the synergistic effects of the harsh space environment for several months. In this paper, a few laser and optica...

National Technical Information Service (NTIS)

40
Resonant Scattering of Polaritons as Composite Particles.
1968-01-01

To calculate correctly the scattering of light by phonons or impurities in a crystal, the true asymptotic scattering states of the coupled system of crystal plus light (polaritons) should be used. When the light frequency is close to one exciton or optica...

National Technical Information Service (NTIS)

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41
Recent Results in the Development of a Global Medium-Energy Nucleon-Nucleus Optical-Model Potential.
1988-01-01

Initial results are presented for the determination of a global medium-energy nucleon-nucleus phenomenological optical-model potential using a relativistic Schroedinger representation. The starting point for this work is the global phenomenological optica...

National Technical Information Service (NTIS)

42
Radiative forcing of the stratosphere by S02 gas, silicate ash - NASA

assumes that Beer's law is satisfied at all points along the opticaI path (i.e. the ... violation of Beer's law and used the multiple scattering model. ...

NASA Website

43
Prediction of Optical Image Quality Near the Sea Surface from Meteorological Measurements.
1982-01-01

This report presents a mechanism for calculation of the optical index structure constant from bulk meteorological measurements (air and water temperatures, wind speed, air humidity) made over the ocean. From this and a formulation of the near field optica...

National Technical Information Service (NTIS)

44
Photochromics for Eye Protection Against Nuclear Explosion.
1969-01-01

Photochromic SrTiO3 has been investigated with the aim of understanding the photochromic process in SrTiO3 and of improving the material for use as eye protection against nuclear explosion. The charge transfer model has been clarified and extended. Optica...

National Technical Information Service (NTIS)

45
Optoelectronic MQW Devices and Systems for Application in Optically Controlled Millimeter-Wave Oscillators.
1996-01-01

The objective of this program was the realization of optically controlled millimeter wave and microwave GaAs and InP based circuits. The primary goal was the development of heterojunction bipolar transistors (HBTs) with the ability to be controlled optica...

National Technical Information Service (NTIS)

46
Optical Parametric Amplification for High Peak and Average Power.
2001-01-01

Optical parametric amplification is an established broadband amplification technology based on a second-order nonlinear process of difference-frequency generation (DFG). When used in chirped pulse amplification (CPA), the technology has been termed optica...

National Technical Information Service (NTIS)

47
Optical Damage Threshold of Silicon for Ultrafast Infrared Pulses.
2006-01-01

While silicon has several properties making it an attractive material for structure-based laser-driven acceleration, its optical damage threshold, a key parameter for high-gradient acceleration, has been unknown. Here we present measurements of the optica...

National Technical Information Service (NTIS)

48
Mode Control Technology for High Performance Solid State Lasers.
1973-01-01

The report presents the results of a nine month R and D program to extend the capability for generation of diffraction limited energy from pulsed Nd:YAG lasers. Theoretical results include a first order error analysis for the sensitivity of complex optica...

National Technical Information Service (NTIS)

49
MM&T: Bibliography on Optical Testing with Appendix.
1982-01-01

The following is a major expansion of 'Bibliography on Various Optical Testing Methods,' by Daniel Malacara, Alejandro Cornejo, and M. V. R. K. Murty which appeared in Applied Optica, 14, 1065 - 1080 (1975). It is computerized to allow for easy update and...

National Technical Information Service (NTIS)

50
Linear Digital Imaging System Fidelity Analysis Formulation

[5] E.H. Linfoot. Quality Evaluations of Optical Systems. Optica Acta, 5, 1-14, ... [A] P.B. Fellgett and E.H. Linfoot. On the Assessment of Optical Images ...

NASA Website

51
Industrial Hygiene Surveys of Occupational Exposures to Mineral Wool.
1980-01-01

Exposures to mineral wool fibers, total suspended particulate material, respirable particulate material, and trace metals were evaluated among users and producers of mineral wool. Study methods included breathing zone air sampling with gravimetric, optica...

National Technical Information Service (NTIS)

52
INFLUENCE OF HYPOXIA ON COLOR VISION
1959-03-01

... Yusfin, BS Franq~n and GN Rautian, Tr#*mglat~d ertom Dok. Akad. ... optiki [Problems of Physiological Optica7, 6, 120 (1948). 5. GN RAUTIAN, Dok. ...

DTIC Science & Technology

53
ICI Optical Data Storage Tape.
1992-01-01

Optical data storage tape is now a commercial reality. The world's first successful development of a digital optical tape system is complete. This is based on the Creo 1003 optical tape recorder with ICI 1012 write-once optical tape media. Flexible optica...

National Technical Information Service (NTIS)

54
Hybrid (Optical/Electronic) Computing and Digital Optical Computing.
1988-01-01

Hybrid optical-analog/electronic computing is performed for optical image processing, optical pattern recognition and optical solution of partial differential equations. For example, image processing designed and fabricated space variant filters to optica...

National Technical Information Service (NTIS)

55
Fermi Surface and Optical Properties of Potassium.
1970-01-01

The optical conductivity of potassium is calculated using a simple, non-local pseudopotential obtained by fitting the computed Fermi surface to experimental data. The results of the calculation are in good agreement with experiments of Smith on the optica...

National Technical Information Service (NTIS)

56
Experimental Spatial Acquisition and Tracking System for Optical Intersatellite Crosslinks.
1991-01-01

Optical intersatellite communications crosslinks will operate with much higher antenna gains and hence more stringent pointing and tracking requirements than do present RF and microwave-based systems. The design and experimental demonstration of an optica...

National Technical Information Service (NTIS)

57
De Rol Van De Geintegreerde Optica In De Optische ...
1989-09-01

... Dispersie veroorzaskt een ver- breding van de optische puls als deze door de glasvezel propageert. Dit beperkt de maximale bitrate. Page 10. ...

DTIC Science & Technology

58
Applications of Nuclear Track Detectors.
1980-01-01

The results of a scientific research-work are summarized. Nuclear track detectors were used for new applications or in unusual ways. Photographic films, nuclear emulsions and dielectric track detectors were investigated. The tracks were detected by optica...

National Technical Information Service (NTIS)

59
Acta Optica Sinica (Selected Articles).
1986-01-01

Contents: The Second National Conference On Basic Optics and the Technical Committee Meeting on Basic Optics Held at Jungbo Lake; and The Inhomogeneity of the Optical Thin Film Determined by Real Time Elliptic Polarization Measurement. Abstract: An automa...

National Technical Information Service (NTIS)

60
AVIRIS (Airborne Visible/Infrared Imaging Spectrometer) Foreoptics, Fiber Optics and on-Board Calibrator.
1987-01-01

The foreoptics, fiber optic system and calibration source of the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) are described. The foreoptics, based on a modified Kennedy scanner, is coupled by optical fibers to the four spectrometers. The optica...

National Technical Information Service (NTIS)

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61
Treatment of Neuromyelitis Optica: Current Debate
2008-07-01

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that largely affects optic nerves and spinal cord. Recent studies have identified an elevation of serum anti-aquaporin 4 antibody as a hallmark of NMO. Typical cases of NMO significantly differ from multiple sclerosis (MS) in immunological ...

PubMed Central

62
Neuromyelitis optica, psychiatric symptoms and primary polydipsia: a case report.

Neuromyelitis optica (NMO) is an aggressive demyelinating disease that typically affects the optic nerves and spinal cord. While it is increasingly recognized that cerebral lesions are common in NMO, there have been no reported cases of NMO presenting with psychiatric symptoms and polydipsia. We describe a patient with classic signs and symptoms of NMO who also demonstrated ...

PubMed

63
Leber hereditary optic neuropathy mimicking neuromyelitis optica.
2011-09-01

Leber hereditary optic neuropathy (LHON) is rarely associated with multiple sclerosis-like features. We present a case of a 65-year-old African American woman with LHON masquerading as neuromyelitis optica (NMO). We highlight the features of the clinical examination and MRI that were suggestive of an alternative diagnosis and review the literature regarding LHON and multiple ...

PubMed

64
An early case of neuromyelitis optica: on a forgotten report by Jacob Lockhart Clarke, FRS.
2011-06-20

We discuss a forgotten report by the famous British neuroanatomist, neuropathologist and neurologist Jacob Augustus Lockhart Clarke (1817-1880) about a 17-year-old girl with bilateral optic neuritis and longitudinally extensive transverse myelitis. This report, which appeared in 1865, i.e. 15 years prior to Wilhelm Erb's much-cited paper on the coincidence of optic neuritis and acute myelitis, ...

PubMed

65
Myasthenia Gravis-Associated Neuromyelitis Optica-Like Disease: An Immunological Link Between the Central Nervous System and Muscle?
2011-08-01

BACKGROUND: Although overt involvement of the central nervous system (CNS) in myasthenia gravis (MG) is considered rare, hyperreflexia is a common and yet unexplained finding. Aquaporin 4 (AQP4), the target autoantigen in neuromyelitis optica, is expressed both in the CNS and in the neuromuscular junction. OBJECTIVES: To evaluate the prevalence of even mild CNS involvement in ...

PubMed

66
Viabilidade da utilizacao de uma fonte de Se sup(75) na analise de uranio, torio e os elementos terras-raras, em fluorescencia por energia dispersiva de raios-x. (Viability utilization of one Se sup(75) source in the analysis of uranium, thorium and rare earths for use on energy dispersive x-ray fluorescence).
1989-01-01

This work is a study about the viable utilization of one Se sup(75) source as an excitation source for the use of Energy Dispersive X-Ray Fluorescence (EDXRF), in the analysis of Uranium, Thorium and the Rare Earths. The following arrangement was build up...

National Technical Information Service (NTIS)

67
Estudio de procesos de excitacion y desexcitacion de niveles de la molecula de N(sub 2). Fluorescencia inducida por electrones y laser. (Excitation and deexcitation of N2 molecular levels. Induced fluorescence by electrons and laser).
1989-01-01

The electron impact excitation followed by fluorescence induced by N(sub 2)-laser absorption was used to study the lifetime of the lowest vibrational level of the B (sup 3)(pi)(sub g) electronic state of N(sub 2). The experimental result of this work is 1...

National Technical Information Service (NTIS)

68
Estandarizacion de un metodo de cuantificacion de azufre por fluorescencia de rayos X, en una solucion extractora de sulfato disponible en suelo. (Standardization of a sulfur quantitative analysis method by X ray fluorescence in a leaching solution for bio-available sulfates in soil).
1989-01-01

A method for bio-available sulfate analysis in soils is described. A Ca(H2PO4) leaching solution was used for soil samples treatment. A standard NaSO4 solution was used for preparing a calibration curve and also the fundamental parameters method approach ...

National Technical Information Service (NTIS)

69
Determinacao dos produtos de fissao em rejeito liquido de atividade alta por fluorescencia de raios-X correcao da interferencia espectral pela razao das intensidades. (Fission products determination in high activity waste solution by wavelength dispersive X-ray fluorescence spectral interference correction by intensity ratio).
1988-01-01

Fission products Se, Rb, Y, Zr, Mo, Ru, Rh, Pd, Te, Cd, Cs, Ba, La, Ce, Pr, Nd, Sm, Eu and Gd were determined in simulated high activity radioactive waste solution by wavelength dispersive X-ray fluorescence spectrometry without chemical separation. Thin ...

National Technical Information Service (NTIS)

70
Determinacao de ferro total em minerio de ferro por fluorescencia de raios-x utilizando o efeito Compton: comparacao com outras tecnicas analiticas. (Determination of total iron in iron ore by x-ray fluorescence analysis using the Compton effect: comparison with others analytical techniques).
1991-01-01

Total iron in iron ores is determines by X-ray fluorescence analysis method using the compton effect. The Bragg angle is determined for compton no-coherent scattering related to K alpha of Rhodium. This measurement procedure can be used for best fitting o...

National Technical Information Service (NTIS)

71
Correcao de elementos interferentes: uma otimizacao necessaria para analise de Co em acos Mn, via espectrometria de fluorescencia de raios-x. (Interfering elements correction: a necessary optimization for Co analysis from Mn steels, using x-ray fluorescence spectrometry).
1991-01-01

The interference of manganese, copper and aluminium in cobalt analysis from manganese steels is studied. The method used in this experiment is X-ray fluorescence spectrometry and a comparative study is also presented. (M.V.M.). (Atomindex citation 24:0441...

National Technical Information Service (NTIS)

72
Aplicacion del analisis por activacion neutronica y la fluorescencia de rayos X en el estudio de la composicion elemental de Chenopodium Quinoa Willd. (Study of the elemental composition of Chenopodium Quinoa Willd by fast neutron activation analysis and X ray fluorescence analysis).
1996-01-01

By means of x-ray fluorescence and fast neutron activation analysis the nitrogen content has been determined in samples of roots, stems, leaf, flowers and grains from Quinua (Chenopodium Quinoa Willd), which was previously treated with fertilizer. (Atomin...

National Technical Information Service (NTIS)

73
Estudo de tratamentos termicos e irradiacao na ametista natural por absorcao otica. (Study of thermal treatments and irradiation on natural amethyst by optical absorption).
1987-01-01

Thermal treatment effects on the samples of amethyst from Minas Gerais and Rio Grande do Sul, through optical absorption measurements, are studied. The effects of cobalt 60 gama ray radiation on the amethyst from Minas Gerais through optical absorption me...

National Technical Information Service (NTIS)

74
Efeito de deficiencias minerais na absorcao de fosforo pelo arroz (Oryza sativa L.). (Effect of mineral deficiencies on the uptake of phosphorus by rice (Oryza sativa L.)).
1987-01-01

The effects of both incipient and accentuated defficiency of macronutrients on the uptake of (sup 32)P labelled phosphate by two rice cultivars IAC 164 and IAC 899. (L.M.J.). (Atomindex citation 21:086567)

National Technical Information Service (NTIS)

75
Absorption Equilibrium of Solar Radiation Between the Two Hemispheres of Earth Equilibrio DA Absorcao DA Radiacao Solar Entre OS Dois Hemisferios DA Terra.
1980-01-01

The absorption of solar radiation by the Earth is a function of astronomical parameters (height, distance from the Sun) and of terrestrial parameters (albedo, bio-albedo, latent heat). The distribution of ocean and land may induce a disequilibrium of the ...

National Technical Information Service (NTIS)

76
Absorcao de Tecnologia E O Aprendizado Tecnologico: Um Estudo DA Dinamica Do Processo E de Fatores Intervenientes (Technology Absorption and Technological Learning: A Study of the Dynamics of the Process and Intervening Factors).
1992-01-01

This work intends to identify and analyze some of the factors that influence the process of technological absorption and learning, focusing on Brazilian organizations both in the productive and in the R&D sectors. It is composed of three major parts. The ...

National Technical Information Service (NTIS)

77
Multi-wavelength diffusive optical tomography using independent component analysis and time reversal algorithms
2011-06-01

Optical imaging using independent component analysis (OPTICA) and time reversal optical tomography (TROT) approaches are used to detect, locate, and obtain cross-section images of two tumor pieces inside a model human breast assembled using ex vivo human breast tissues and configured as a semi-cylindrical slab of uniform thickness. The experimental arrangement realized a ...

NASA Astrophysics Data System (ADS)

78
Moyamoya Disease Presenting as Thalamic Hemorrhage in A Patient with Neuromyelitis Optica and Sj�gren's Syndrome.
2011-05-13

A 52-year-old woman was admitted to the hospital with right thalamic hemorrhage. A carotid angiogram revealed occlusion of the terminal portions of the bilateral internal carotid arteries with basal moyamoya vessels, which was diagnosed as moyamoya disease (MMD). At 31 years of age, she was diagnosed with multiple sclerosis because of optic neuritis and myelitis. Paraplegia appeared 14 days after ...

PubMed

79
Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) syndrome in a patient with neuromyelitis optica spectrum disorder and anti-aquaporin-4 antibody.
2011-02-07

This report describes, for the first time, an occurrence of wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) in a 19-year-old female with neuromyelitis optica (NMO) spectrum disorder, who had anti-aquaporin-4 (AQP4) antibody. A high signal intensity lesion on T2-weighted MRI was detected in the midbrain tegmentum adjacent to the aqueduct, and presumably involved the ...

PubMed

80
Systemic sclerosis in aquaporin-4 antibody-positive longitudinally extensive transverse myelitis.
2011-02-05

We report on the first patient with a relapsing, anti-aquaporin-4 (AQP-4) antibody-positive, longitudinally extensive transverse myelitis (LETM) who developed systemic sclerosis (SSc). A 62-year-old woman, who presented with bilateral, distal lower limb and perineal numbness, developed clinical manifestations and paraclinical features of SSc. Spinal cord imaging revealed lesions that were ...

PubMed

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81
Ocular Oscillations in the Neuromyelitis Optica Spectrum.
2011-05-27

Four French West Indian women complained of oscillopsia and were found to have an acquired eye movement disorder. In 3 of them, different types of nystagmus were found, including upbeat, downbeat, and central form of vestibular nystagmus. One developed opsoclonus-myoclonus syndrome. Three patients had neuromyelitis optica antibodies, and 3 had brainstem abnormalities detected ...

PubMed

82
Neuromyelitis optica associated with subacute human T-lymphotropic virus type 1 infection.
2010-07-17

Although human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy, or tropical spastic paraparesis (HAM/TSP), is usually considered as a progressive myelopathy, a subacute variant has been described. It is unusual for optic neuritis (ON) to be associated with an HTLV-1 infection. Neuromyelitis optica (NMO) is characterised by severe attacks of acute transverse myelitis ...

PubMed

83
Neuromyelitis Optica-AQP4: An Update.
2011-09-16

Devic disease (neuromyelitis optica [NMO]) is an idiopathic inflammatory demyelinating and necrotizing disease characterized by optic neuritis and transverse myelitis, either simultaneously or in isolation. NMO is often idiopathic but may also be associated with systemic autoimmune disease. The prognosis of NMO is severe, especially in those with early and recurrent relapses. ...

PubMed

84
Massive astrocyte destruction in neuromyelitis optica despite natalizumab therapy.
2011-08-25

Auto-antibody mediated astrocyte injury is implicated as a primary event in neuromyelitis optica (NMO) by biomarker, post-mortem and experimental studies that differentiate the condition from multiple sclerosis. We describe the clinical, radiological and neuropathological features of a severe cerebral attack in a natalizumab-treated patient with relapsing myelitis and serum ...

PubMed

85
Identification of peptide targets in neuromyelitis optica.
2011-05-28

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that predominantly affects the optic nerves and spinal cord. Recombinant antibodies (rAbs) generated from clonally expanded plasma cells in an NMO patient are specific to AQP4 and pathogenic. We screened phage-displayed peptide libraries with these rAbs, and identified 14 high affinity linear and ...

PubMed

86
Devic's neuromyelitis optica: a clinicopathological study of 8 patients.
1993-08-01

We report the clinical, imaging, and laboratory features of 8 patients with Devic's neuromyelitis optica. All patients had severe myelopathy and optic neuritis. In no patient was the brain, the brainstem, or the cerebellum affected, even after several years of disease. Various immunosuppressive treatments failed to benefit the patients, 5 of whom died. Autopsies of these 5 ...

PubMed

87
Estudo para a determinacao de samario europio, terbio, disprosio e itrio em matriz de oxido de gadolinio por espectrofotometria de absorcao atomica em forno de grafita. (Study for the determination of samarium, europium,terbium, dysprosium and yttrium in gadolinium oxide matrix by means of atomic absorption spectrophotometry using a graphite furnace).
1985-01-01

A study for determination of samarium, europium, terbium, dysprosium and yttrium in a gadolinium oxide matrix by atomic absorption spectrophotometry using a graphite furnace is presented. The best charrring and atomization conditions were estabilished for...

National Technical Information Service (NTIS)

88
Estudo para a determinacao de impurezas de terras raras em matrizes de oxidos de samario, terbio e disprosio por espectrometria de absorcao atomica com forno de grafita. (Determination of trace amounts of rare earth elements in samarium, terbium and dysprosium oxides by graphite furnace atomic-absorption spectrometry).
1990-01-01

A graphite furnace atomic-absorption spectrometry method for the determination of neodymium, europium, terbium, dysprosium and yttrium at trace level in samarium oxide; of samarium, europium, dysprosium, holmium, erbium and yttrium in terbium oxide and of...

National Technical Information Service (NTIS)

89
Estudo de uma nova tecnica de introducao de amostras solidas combustiveis para determinacao de elementos volateis por espectrofotometria de absorcao-atomica com chama. (Study of new technique of solid combustible materials to determination of volatile elements by flame atomic absorption spectrophotometry).
1988-01-01

A new technique for direct trace element analysis of solid combustible materials is described. The samples (up to 10 mg) are weighed on a graphite platform wich is then placed in a quartz tube, at the focal point of three infrared lamps. When the lamps ar...

National Technical Information Service (NTIS)

90
Absorcao real do fosforo dos fosfatos bicalcico, monoamonio, supertriplo e de ureia em bovinos, atraves da diluicao do radiofosforo (P-32). (True absorption of phosphorus from di calcium phosphate, mono ammonium phosphate, triple superphosphate and urea-phosphate in cattle by the radio phosphorus dilution technique).
1990-01-01

With the aim to study the utilization of alternative sources of phosphorus by ruminants. Twenty four males steers, with 250 Kg live weight and 18 months of age, were allocated in four groups of six animals each. The animals were housed in individual pens ...

National Technical Information Service (NTIS)

91
Fluorescence Uranium Determination. I. Design of Equipment and Testing; DETERMINACION DE URANIO POR FLUORESCENCIA. I. PROYECTO DE EQUIPO Y COMPROBACION
1960-01-01

Equipment for analysis by fluorescence was developed in order to make a determination of uranium at such a low concentration that previously could not be determined by the most sensitive analytical methods. This new fluorimeter was adapted to measure the fluorescence emitted by the sodium fluoride - sodium carbonate - potassium carbonate excited by ultraviolet light of 3,650 A. The ...

Energy Citations Database

92
Variational Effective Index Method for 3D Vectorial Scattering Problems in Photonics: TE Polarization

extension of the effective index method," Optica Applicata, Vol. 36, No. 1, 51�56, 2006. 2. MEEP, "Free finite-difference time-domain simulation software package developed at MIT," http://www.ab-initio.mit.edu/meep

E-print Network

93
Time-Resolved and Spectroscopic Three-Dimensional Optical Breast Tomography.
2007-01-01

The research carried out during the current reporting period included: (a) Use of optical tomographic imaging using independent component analysis (OPTICA) developed during the first reporting period to image targets in ex vivo breast tissue specimens, (b...

National Technical Information Service (NTIS)

94
The Optical Response of a Double Quantum Well Driven by ...
1993-05-20

Page 1. [he 26 Optica 04sons of0a Vobeqatm WlDie *.~~ AidC4S 2. IMPnOSTii Rr 1a i andOR Hp "S AetiuVRI A. nTU NOS U&G.MCIr-U N ...

DTIC Science & Technology

95
Recurrent neuromyelitis optica in Brazilian patients: clinical, immunological, and neuroimaging characteristics.
2009-12-07

Neuromyelitis optica has not been thoroughly studied in Brazilian patients following the discovery of NMO-IgG and its specific antigen aquaporin-4. In this study we aimed to describe the clinical NMO-IgG immunological status and neuroimaging characteristics of recurrent neuromyelitis optica in a series Brazilian patients. We undertook a retrospective study ...

PubMed

96
Proportionality between In situ Carbon Assimilation and Bio-Optical Measures of Primary Production in the Gulf of Maine in Summer. (Reannouncement with New Availability Information).
1993-01-01

The optical determinants to primary production (irradiance, phytoplankton absorption, chlorophyll, and quantum yield) are used in a model to compare with measured values of daily carbon assimilation in the Gulf of Maine. The correlation between the optica...

National Technical Information Service (NTIS)

97
Prediction of Optical Image Quality Near the Sea Surface from Meteorological Measurements.
1982-01-01

This report presents a mechanism to calculate the optical index structure constant, C2N from bulk meteorological measurements (air and water temperatures, wind speed, air humidity) made over the ocean. From this, and a formulation of the near-field optica...

National Technical Information Service (NTIS)

98
Oso-8 X-Ray Observations of AM Herculis.
1977-01-01

Hard X-ray observations of the binary system AM Her were coincident with soft X-ray and ground-based optical measurements. In the 2-60 KeV band, variability was detected with an eclipse during phases 0.5 to 0.7 with respect to the 0. d 12892 period optica...

National Technical Information Service (NTIS)

99
Optical high resolution cross section imaging of a human breast model using independent component analysis
2007-03-01

Optical imaging using independent component analysis (OPTICA) is enhanced to provide a high resolution cross section imaging of objects in a turbid medium by a backprojection technique. The performance is demonstrated by imaging a human breast model made of ex vivo human breast tissues. Cancerous site of 5mm size is detected at the midplane of the 33mm thick breast model. The ...

NASA Astrophysics Data System (ADS)

100
Optical coherence tomography differs in neuromyelitis optica compared with multiple sclerosis
2009-03-24

Background:Neuromyelitis optica (NMO) is associated with destructive inflammatory lesions, resulting in necrosis and axonal injury. Disability from multiple sclerosis (MS) is due to a combination of demyelination and varying axonal involvement. Optical coherence tomography (OCT), by measuring retinal nerve fiber layer (RNFL) as a surrogate of axonal injury, has potential to ...

PubMed Central

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101
Optica Applicata, Vol. XXXVI, No. 4, 2006 A system for magnetooptical cooling

observed in many fields of modern atomic and quantum physics, such as e.g.: quantum degenerate systems.S., ZILIO S., JULIENNE P.S., Experiments and theory in cold and ultracold collisions, Reviews of Modern atoms KRZYSZTOF KOWALSKI1* ,EMILIYA DIMOVA-ARNAUDOVA2 ,KRZYSZTOF FRONC1 ,SANKA GATEVA3 , MALGORZATA

E-print Network

102
Medidas de transicoes opticas em candidatos a meio laser ativo: aplicacao a centros de cor. (Optical transition measurements in laser active medium candidates: application to color centers).
1990-01-01

In the present work we describe a spectroscopy method that can determine the energy level diagram of the species under investigation, the decay time, quantum efficiency and emission cross section. Firstly, the decay time was measured by using a sinusoidal...

National Technical Information Service (NTIS)

103
Journal of Biomedical Optics 15(6), 066004 (November/December 2010) Adaptive optics multiphoton microscopy

Journal of Biomedical Optics 15(6), 066004 (November/December 2010) Adaptive optics multiphoton Laboratorio de �Optica Campus de Espinardo (CiOyN) Murcia, 30100 Spain Abstract. We develop an adaptive optics; adaptive optics; human ocular tissue. Paper 10192PRR received Jun. 8, 2010; revised manuscript received Aug

E-print Network

104
Invited Paper Application of Superresolution Algorithm

.1, 267-278 (1995). 7. R.W. Gerchberg, "Super-Resolution through Error Energy Reduction," Optica Acta 709 for improving the resolution of microwave synthetic-aperture radar (SAR) In this paper we review the Super for different features of the image --prominentpoints versus extended, diffuse areas. Keywo rds : Super-resolution

E-print Network

105
Instrument effects in polarized infrared images Joseph A. Shaw, MEMBER SPIE

.-P. Gemund, E. Kreysa, and J. Wolf, "Far-infrared imaging, polarimetry, and spectro- photometryInstrument effects in polarized infrared images Joseph A. Shaw, MEMBER SPIE NOAA Environmental uncertainties less than 1%. Subject terms: infrared polarization; thermal imaging; remote sensing. Optica

E-print Network

106
Estudo dos efeitos da radiacao gama nas propriedades mecanicas e opticas dos policarbonatos. (Gamma radiation effect study in polycarbonate optical and mechanics properties).
1991-01-01

Polycarbonates (PC) are used in different industrial applications due to their excellent dielectric characteristics, impact resistance, and high temperature resistance. In some of these applications, the polycarbonates are exposed to gamma radiation which...

National Technical Information Service (NTIS)

107
Estudo da anisotropia optica do oxido de niobio. (Study of optics anisotropy of niobium oxide).
1988-01-01

This work shows the use of ''in-situ'' optical techniques in electrochemical experiments to determine the refractive indexes of an anisotropic film. ''In situ'' reflectance measurements allow to study the behavior of a film during its growth process: in o...

National Technical Information Service (NTIS)

108
Determination of the Radiation Diagram of Reflecting Antennas Using the Asymptotic Physical Optics Method Determinacao Do Diagrama de Radiacao de Antenas Refletoras Usando O Metodo DA Optica Disica Assintotica.
1982-01-01

The field scattered by a general surface of revolution, when illuminated with linearly, circularly, or elliptically polarized feeds, can be calculated by the physical optics method, which consists of the integration of the currents induced in the reflecto...

National Technical Information Service (NTIS)

109
Coordinated Observations of X-ray Bright BL Lacertae Objects. Semiannual Status Report March 15, 1985-September 15, 1985.
1985-01-01

Simultaneous multifrequency observations of the BL Lac object Mkn421 covering radio through X-ray wavelengths were performed. Composite multifrequency spectra of the central nonthermal component were obtained at the two epochs after subtracting the optica...

National Technical Information Service (NTIS)

110
Cluster-Bethe Lattice Calculation for the Electronic Structure of Hydrogen Centers in Alkali-Halides.
1979-01-01

The Cluster-Bethe lattice (CBL) method to calculate the electronic structure of the hydrogen centers U, U sub 1 , U sub 2 , U sub 3 in alkali halides has been used. The results show the adequacy of the CBL in the interpretation of the nature of the optica...

National Technical Information Service (NTIS)

111
PREFACE: International Conference on Control and Synchronization of Dynamical Systems (CSDS-2005)
2005-01-01

This volume of Journal of Physics: Conference Series contains selected articles by the participants at the International Conference on Control and Synchronization of Dynamical Systems (CSDS-2005) organized by Centro de Investigaciones en Optica (CIO) in cooperation with the Society for Industrial and Applied Mathematics (SIAM), which was held in Leon, Guanajuato, Mexico on 4-7 ...

NASA Astrophysics Data System (ADS)

112
Detecci�n y estudio mediante Fluorescencia Inducida por L�ser de radicales libres formados por Disociaci�n Multifot�nica Infrarroja
2003-01-01

Una de las principales aplicaciones actuales de los procesos de disociaci�n multifot�nica inducidos por radiaci�n l�ser infrarroja (DMI) es la producci�n de radiales libres, con el fin de estudiar sus propiedades cin�ticas y espectrosc�picas. La disociaci�n de mol�culas poliat�micas en el IR con l�seres de CO2 tiene lugar desde la superficie de energ�a molecular mas baja y ...

NASA Astrophysics Data System (ADS)

113
Efeito da materia organica e de um inibidor da nitrificacao na absorcao de (sup 15)N H(sub 4) e (sup 15)N O(sub 3) pelo milho. (The effect of organic matter and nitrification inhibitor on (sup 15) N H(sub 4) and (sup 15) N O(sub 3) absorption by the maize).
1974-01-01

The effect of the forms (sup 15) N H(sub 4) and (sup 15) N O(sub 3) in presence or absence of organic matter and of the nitrification inhibitor AM (2-amino-4-chloro-6-methyl-pyrimidine) in dry matter weight and nitrogen content of the plant derived from s...

National Technical Information Service (NTIS)

114
Absortion of Vitamin B-12 (Co-60) in Gastrectomized Patients; ABSORCAO DA VITAMINA B-12 (CO-60) EM PACIENTES GASTRECTOMIZADOS
1960-01-01

The absorption of radioactive vitamin B/sub 1//sub 2/ was studied in subtotal gastrectomized patients with either Billroth I or Billroth II anastomosis and in total gastrectomized patients. The results were compared with absorption in a control group of non-gastrectomized patients. Absorption was evaluated through fecal excretion using the Halsted technique and through urinary ...

Energy Citations Database

115
Absorption of Co$sup 60$ Labeled Vitamin B$sub 12$ in the Gastrectomized; ABSORCAO DA VITAMINA B-12 (Co-60) EM GASTRECTOMIZADOS
1959-05-01

The absorption of vitamin B/sub 12/ by individuals with a partial or total gastrectomy was investigated using B/sub 12/ in aqueous solution containing 0.5 mu c of Co/sup 60/100 ml of solution. The activity in fecal and urinary eliminations is representative of the amount absorbed in the gastrointestinal tract. The results obtained are tabulated and show that in total gastrectomies ...

Energy Citations Database

116
Reversible stenosis of large cerebral arteries in a patient with combined Sj�gren's syndrome and neuromyelitis optica spectrum disorder.
2008-05-21

We report a 49-year-old woman with neuromyelitis optica (NMO) spectrum disorder coexisting with Sj�gren's syndrome (SS). She presented with acute brainstem symptoms and transverse myelitis. Brain MRI showed focal high signal intensity lesions in the hypothalamus and the pontine tegmentum on T2-weighted and FLAIR images. MRA revealed stenotic changes of the bilateral middle ...

PubMed

117
Recurrent acute rhombencephalomyelitis in an adult or neuromyelitis optica? Presentation of a case.
2011-06-01

INTRODUCTION: The lack of accepted homogeneous criteria for the definition of some demyelinating diseases makes diagnostic characterization difficult and limits data interpretation and therapeutic recommendations. Recurrent encephalomyelitis (ADE-R) along with borderline cases of neuromyelitis optica (NMO) are especially controversial. OBJECTIVE: To describe the clinical and ...

PubMed

118
Pathogenic T cell responses against aquaporin 4.
2011-04-06

Inflammatory lesions in the central nervous system of patients with neuromyelitis optica are characterized by infiltration of T cells and deposition of aquaporin-4-specific antibodies and complement on astrocytes at the glia limitans. Although the contribution of aquaporin-4-specific autoantibodies to the disease process has been recently elucidated, a potential role of ...

PubMed

119
New trends in light and optics teaching; building bridges to the information society--the OPTICA XXI project
2002-05-01

In our emerging Society of Information, Light and Optics have a crucial importance not only in Science and Technology but also in the widest range of aspects of our every day life. In this communication we will present a project presented to the EC program Socrates action Comenius 3. The project aims the establishment of a network, the OPTICA XXI network, involving eighteen ...

NASA Astrophysics Data System (ADS)

120
Neuromyelitis optica: an update.
2011-04-15

Neuromyelitis optica (NMO) is an inflammatory condition characterized by the selective involvement of the optic nerves and spinal cord, and by a frequent relapsing course. Many clinical, laboratory and neuroimaging studies have provided useful means to distinguish NMO from multiple sclerosis (MS). The detection of aquaporin-4 (AQP4) antibodies has broadened the spectrum of the ...

PubMed

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121
Neuromyelitis optica: Passive transfer to rats by human immunoglobulin.
2009-06-21

Recurrent attacks of optic neuritis and myelitis are the hallmarks of both neuromyelitis optica (NMO) and multiple sclerosis (MS). NMO immunoglobulin G (NMO-IgG), which recognizes astrocytic aquaporin-4 (AQP4) water channels, is a specific serum autoantibody that distinguishes NMO from MS. The pathogenic role of the anti-AQP4 antibody (AQP4-Ab, NMO-IgG) in NMO has been ...

PubMed

122
Neuromyelitis optica and astrocytic damage in its pathogenesis.
2011-03-11

Neuromyelitis optica (NMO) is characterized by severe optic neuritis and longitudinally extended, transverse myelitis. There have been long controversial whether NMO is a variant of multiple sclerosis (MS) or a different disease. However, since the discovery of an NMO-specific autoantibody to aquaporin 4 (AQP4), a dominant water channel in the central nervous system densely ...

PubMed

123
Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica.
2008-03-11

Neuromyelitis optica (NMO) is a rare CNS inflammatory disorder that predominantly affects the optic nerves and spinal cord. Recent serological findings strongly suggest that NMO is a distinct disease rather than a subtype of multiple sclerosis. In NMO, serum antibodies, collectively known as NMO-IgG, characteristically bind to cerebral microvessels, pia mater and Virchow-Robin ...

PubMed

124
Intractable hiccup caused by medulla oblongata lesions: a study of an autopsy patient with possible neuromyelitis optica.
2009-07-03

We report the first autopsy verification of medulla oblongata lesions involving bilateral nucleus tractus solitarius (NTS) as a cause of intractable hiccup in an autopsy patient. The female patient first developed pain and weakness in the lower limbs and urinary incontinence at age 48, and was given a diagnosis of myelitis. Intractable hiccup was accompanied by urinary retention on the third ...

PubMed

125
Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica
2011-03-01

Neuromyelitis optica (NMO) is an inflammatory disease affecting the optic nerve and spinal cord, in which autoantibodies against aquaporin 4 (AQP4) water channel protein probably play a pathogenic role. Here we show that a B-cell subpopulation, exhibiting the ...

PubMed Central

126
Devic syndrome: a diagnostic dilemma.
2011-02-01

Neuromyelitis optica (NMO, also known as Devic syndrome or Devic disease) is a rare clinical entity. Early recognition and prompt treatment can save patients from long-term disability, especially in themonophasic variant of disease. A 24-year-old African American female presented with high-grade fever for 1 day associated with frontal headache, photophobia, and 2 episodes of ...

PubMed

127
Detection of mumps virus RNA in cerebrospinal fluid of patients with neuromyelitis optica.
2011-04-06

Neuromyelitis optica (NMO) is an acute inflammatory disease that preferentially involves the optic nerves and spinal cord. Although many infectious agents, including mumps virus, are postulated to have a role in the pathogenesis of multiple sclerosis (MS), the relationship between NMO and infectious agents remains uncertain. To investigate the relationship between NMO and ...

PubMed

128
Current and future treatment approaches for neuromyelitis optica.
2011-03-01

Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system (CNS) characterized by severe attacks of optic neuritis and myelitis, and which, unlike multiple sclerosis (MS), commonly spares the brain in the early stages. NMO used to be considered as a special form of MS. During the past 10 years, however, the two diseases have been shown to be clearly ...

PubMed

129
Current and future treatment approaches for neuromyelitis optica
2011-03-01

Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system (CNS) characterized by severe attacks of optic neuritis and myelitis, and which, unlike multiple sclerosis (MS), commonly spares the brain in the early stages. NMO used to be considered as a special form of MS. During the past 10 ...

PubMed Central

130
Cat�logo de Radio-Fuentes Opticas con Astrolabio Fotoel�ctrico PAII
1998-01-01

Usando los datos observados en San Juan con el Astrolabio Fotoel�ctrico PAII desde Febrero de 1992 hasta Marzo de 1997, se ha realizado el Cat�logo de Radio-Fuentes Opticas de San Juan conteniendo 69 estrellas. Las observaciones de las posiciones de las radio-fuentes est�n realizadas para la �poca y equinoccio J2000,0 y en un sistema cercano al del FK5. Las precisiones ...

NASA Astrophysics Data System (ADS)

131
CD8CD11a(high) cells decreased in multiple sclerosis but not in neuromyelitis Optica.
2010-02-16

In order to clarify the immunological characteristics of multiple sclerosis (MS) and neuromyelitis optica (NMO), we analyzed CD3, CD4, CD8, CD20, CD4(+)CD25(+), CD4(+)CD29(+), and CD8(+)CD11a(high) cells in peripheral blood from patients with MS (16 stable, 6 active) and NMO (15 stable, 7 active), as well as 9 with NMO spectrum, 6 with clinically isolated syndrome (CIS), and ...

PubMed

132
Bilateral Internuclear Ophthalmoplegia in a Patient with Devic's Neuromyelitis Optica.
2010-11-12

An unusual presentation of Devic's neuromyelitis optica (NMO) disease associated with bilateral internuclear ophthalmoplegia (INO) is described. A 32-year-old pregnant patient was diagnosed with NMO. First symptoms were headache and sudden visual loss in her right eye (RE). Eighteen months ago, she reported other neurologic symptoms such as paresthesia. Based on her visual ...

PubMed

133
Bilateral Internuclear Ophthalmoplegia in a Patient with Devic's Neuromyelitis Optica
2010-11-12

An unusual presentation of Devic's neuromyelitis optica (NMO) disease associated with bilateral internuclear ophthalmoplegia (INO) is described. A 32-year-old pregnant patient was diagnosed with NMO. First symptoms were headache and sudden visual loss in her right eye (RE). Eighteen months ago, she reported other neurologic symptoms such as paresthesia. Based on her visual ...

PubMed Central

134
Anti-aquaporin-4 antibody-positive familial neuromyelitis optica in mother and daughter.
2011-09-01

BACKGROUND: Cases of anti-aquaporin (AQP)-4 antibody-positive familial neuromyelitis optica (NMO) in mothers and daughters are described. PARTICIPANTS: The demographic, clinical, neuroimaging, and anti-AQP-4 antibody status were investigated in four patients from two Asian families with anti-AQP-4 antibody-positive NMO. OBSERVATIONS: NMO was diagnosed in both mothers and ...

PubMed

135
A serological analysis of viral and bacterial infections associated with neuromyelitis optica.
2010-11-05

To evaluate the role of infections in the development of neuromyelitis optica (NMO), 19 patients positive for anti-aquaporin-4 antibody were screened for 24 viral and bacterial infections. Serological evidence of recent viral infection was found in 7 of 15 patients screened during the acute phase of the neurologic illness, which was a significantly more frequent rate of ...

PubMed

136
Simulation of the Focusing DIRC Optics with Mathematica
2010-02-15

The Focusing DIRC is considered for the Barrel PID at a possible Super-B factory. To reduce sensitivity to background, it would be desirable to reduce a size of the present BaBar photon detector. One way to do it is to replace it with a focusing optics and use smaller photon detector pixels. We have simulated the focusing optics with simulation software based on a 3D calculation performed with the ...

Energy Citations Database

137
Neurologic indications for therapeutic plasma exchange: An update.
2011-09-13

Neurologists commonly use therapeutic plasma exchange (TPE, also known as plasmapheresis or therapeutic apheresis) to treat a number of conditions. This concise review examines the most common neurologic indications for therapeutic plasma exchange. It focuses on Guillain-Barr� syndrome and myasthenia gravis and also the role of TPE in chronic inflammatory demyelinating polyneuropathy, ...

PubMed

138
Lyme optic neuritis.
2010-06-08

Lyme optic neuritis (ON) is a rare disease and only a few cases have been reported. We describe two cases of isolated Lyme ON, one with recurrence 9 months after the appearance of initial symptoms. Diagnosis criteria for multiple sclerosis and neuromyelitis optica were not met. The etiological diagnosis was based on European case definition criteria for neuroborreliosis. Both ...

PubMed

139
ISSN 1024 8560, Atmospheric and Oceanic Optics, 2010, Vol. 23, No. 3, pp. 215�221. � Pleiades Publishing, Ltd., 2010. Original Russian Text � Ya.A. Virolainen, Yu.M. Timofeev, A.V. Polyakov, A.B. Uspenskii, 2010, published in Optica Atmosfery i

shown that they have a high informativeness and allow for the recon struction of atmospheric and surface, the vertical structure of the water vapor content and, additionally, the methane and nitrogen monoxide content, "Information Content and Optimisa tion of High Spectral Resolution Remote Measure ments," Adv. Space Res. 21 (3

E-print Network

140
Familial neuromyelitis optica
2010-07-27

Background:Detection of aquaporin-4�specific immunoglobulin G (IgG) has expanded the spectrum of neuromyelitis optica (NMO). Rare reports of familial aggregation have suggested a component of genetic susceptibility but these reports mostly antedated the discovery of the NMO-IgG biomarker and recently updated diagnostic criteria.Methods:We report a case series describing the ...

PubMed Central

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141
Cerebrospinal fluid B-cell expansion in longitudinally extensive transverse myelitis associated with neuromyelitis optica immunoglobulin G.
2011-06-17

A first episode of central nervous system (CNS) demyelination may represent heterogeneous entities such as acute disseminated encephalomyelitis, clinically isolated syndrome, neuromyelitis optica (NMO), or multiple sclerosis. As new immune therapies become available, it is increasingly important to make an early diagnosis. Autoantibodies such as NMO immunoglobulin G (IgG) and ...

PubMed

142
Resoluci�n de observables sensibles a la composici�n de masa de rayos c�smicos a partir de mediciones realizadas con telescopios de fluorescencia atmosf�rica
2010-01-01

The fluorescence detection technique allows a direct measurement of the atmospheric longitudinal profile produced by cosmic rays with energies greater than 1016.5 eV. This calorimetric technique provides the cosmic ray energy, without resorting to simulations, and atmospheric depth where the shower develops the maximum number of particles, an observable sensitive to the chemical composition of the ...

NASA Astrophysics Data System (ADS)

143
[Magnetic-resonance tomography in differential diagnosis of brain lesions in demyelinating and systemic autoimmune diseases].
2005-01-01

An aim of the study was to establish MRT signs that may be useful for differential diagnosis of multiple sclerosis (MS). Three groups of patients have been examined: 300 patients with MS, 35 with demyelinating diseases (acute disseminated encephalomyelitis, neuromyelitis optica--Devic's syndrome); 90 patients with systemic autoimmune diseases (systemic lupus erythematosus, ...

PubMed

144
The limited demyelinating diseases: the voyage of optic neuritis and transverse myelitis to multiple sclerosis and neuromyelitis.
2011-03-01

The spectrum of idiopathic inflammatory-demyelinating disorders of the CNS is classified based on clinical symptoms and signs, clinical severity, lesion distribution, neuroimaging features and cerebrospinal fluid characteristics. There is a wide variety of conditions in this broad spectrum. In some cases, the dissemination in the CNS is limited to the optic nerves and spinal cord. Neuromyelitis ...

PubMed

145
The differential diagnosis of longitudinally extensive transverse myelitis.
2011-06-13

Longitudinally extensive transverse myelitis refers to florid and widespread inflammation of the spinal cord causing T2 hyperintensity on spinal magnetic resonance imaging that is seen to extend over three or more vertebral segments. Whilst rare, longitudinally extensive transverse myelitis is clinically important as it can lead to catastrophic morbidity, and a group of these patients are at risk ...

PubMed

146
T cell deficiency does not reduce lesions in mice produced by intracerebral injection of NMO-IgG and complement.
2011-04-13

We reported recently that intracerebral administration of NMO-IgG with human complement produces neuromyelitis optica (NMO) lesions in mice. We examined the role of T cells in the formation of NMO lesions by comparing brain histopathology in wildtype and nude mice. Brains were co-injected with IgG from NMO patients and human complement. At 24h and 5days, wildtype vs. nude ...

PubMed

147
Subacute rhombencephalitis optica responsive to intravenous immunoglobulins.
2003-01-01

A 53-year-old man presented with optic neuritis, followed within 10 weeks by a subacute progression of weakness, ataxia, and multiple cranial nerve palsies. Cranial magnetic resonance imaging demonstrated multiple T2-hyperintense lesions extending from the ponto-medullary junction to the thalamus and internal capsule. Cerebrospinal fluid analysis showed lymphocytic pleocytosis with elevated ...

PubMed

148
Seropositive antiaquaporin-4 antibody associated with multisegmental myelitis in a patient with paracoccidioidomycosis.
2011-07-30

Since the description of the association between neuromyelitis optica (Devic's disease) and aquaporin 4 IgG antibody (NMO-IgG), the search for this antibody has been considered a highly recommended laboratory test when centromedullary multisegmental lesions are observed by magnetic resonance imaging (MRI). Such MRI lesions have not been confined to acute NMO myelitis because ...

PubMed

149
Persistent or Slow Viral Infections and Related Diseases
1975-05-01

The discovery of persistent transmissible agents by veterinarians has led to striking advances in the infectious cause of neuropathies of human beings. There is evidence for persisting infection in congenital rubella and the herpes group of viruses including cytomegalovirus infections. Hepatitis types A and B are candidates for inclusion in the category of persisting viral infections. The rubeola ...

PubMed Central

150
Pathological study of subacute autoimmune encephalopathy with anti-AQP4 antibodies in a pregnant woman.
2011-09-01

A pregnant woman with extensive brain lesions on magnetic resonance imaging was tested positive for anti-aquaporin4 (AQP4) antibodies. An open biopsy of the left temporal lobe showed pathological changes in both the white and gray matter. Hematoxylin and eosin, Kl�ver-Barrera, and myelin basic protein staining results were indicative of demyelination in the white matter. Loss of AQP4 and glial ...

PubMed

151
Optical constants for thin films of C, diamond, Al, Si, and CVD SiC from 24 A to 1216 A
1988-01-15

A method for deriving optical constants from reflectance vs angle of incidence measurements using a nonlinear least-squares curve-fitting technique based on the chi/sup 2/-test of fit is presented and used to derive optical constants for several thin-film materials. The curve-fitting technique incorporates independently measured values for the film surface roughness, film thickness, and incident ...

Energy Citations Database

152
DEMYELINATING OPTIC NEURITIS IN CHILDREN
2008-10-20

Acute demyelinating optic neuritis in children can occur in isolation or be associated with acute disseminated encephalomyelitis, multiple sclerosis or neuromyelitis optica. Clinical features, neuroimaging, cerebrospinal fluid findings and long term prognosis were reviewed in 26 children diagnosed with optic neuritis at the first presentation of demyelinating disease. The risk ...

PubMed Central

153
Combined optic neuropathy and myelopathy secondary to copper deficiency.
2010-05-10

We report two patients, both with a history of gastric surgery, who presented with progressive optic neuropathy and myelopathy. The patients' symptoms were initially attributed to vitamin B12 deficiency and/or neuromyelitis optica; however, after the neurologic deficits continued to progress with the use of conventional treatments, further evaluation was initiated, and a ...

PubMed

154
[Successful plasma exchange treatment for a case with neuromyelitis optica].
2011-09-01

We report a 13-year-old girl diagnosed with neuromyelitis optica (NMO). We also report that plasma exchange could be performed early in her clinical course as well as her good response to this treatment. At the onset, transient numbness of both upper extremities appeared. Approximately one month thereafter, photesthesia of the left eye disappeared and she visited our hospital. ...

PubMed

155
[Evaluation of blood flow and the cross-sectional area of internal jugular vein in Japanese multiple sclerosis and neuromyelitis optica patients].
2011-06-01

Zamboni et al proposed a new hypothesis for the pathomechanisms of multiple sclerosis (MS): chronic cerebrospinal venous insufficiency (CCSVI). Using Doppler ultrasound and venograms, they found severe extracranial venous stenosis in MS patients. They suggested that a venous obstruction in the neck caused a reflux back into the brain, which led to edema and demyelination. We examined the blood ...

PubMed

156
[An autopsied case of postinfectious neuromyelitis optica in an 84-year-old man].
2011-08-01

An 84-year-old man presented with acute bilateral visual impairment 2 weeks after an upper respiratory tract infection. A few days later, he developed left hemiparesis, followed by paraplegia. The brain magnetic resonance imaging (MRI) showed high-intensity lesions in the right cerebellum, pons, left and right corona radiata, and right putamen. The diffusion weighted image also showed these ...

PubMed

157
Visual field defects of optic neuritis in neuromyelitis optica compared with multiple sclerosis
2010-06-18

BackgroundNeuromyelitis optica (NMO) is an inflammatory demyelinating disease that predominantly affects the optic nerves and the spinal cord, and is possibly mediated by an immune mechanism distinct from that of multiple sclerosis (MS). Central scotoma is recognized as a characteristic visual field defect pattern of optic neuritis (ON), however, the differing pathogenic ...

PubMed Central

158
The Use of Serum Glial Fibrillary Acidic Protein Measurements in the Diagnosis of Neuromyelitis Optica Spectrum Optic Neuritis
2011-08-18

BackgroundGlial fibrillary acidic protein (GFAP) is a specific intermediate filament of the cytoskeleton of the astrocyte and may be used as a specific marker for astrocytic damage. It is detectable in the cerebrospinal fluid following a relapse caused by Multiple Sclerosis (MS) and Neuromyelitis Optica (NMO) spectrum disease. Higher levels are found following an NMO-related ...

PubMed Central

159
TNF-? and IL-10 downregulation and marked oxidative stress in Neuromyelitis Optica
2009-06-02

BackgroundNeuromyelitis optica is a central nervous system demyelinating and inflammatory syndrome. The objective of this study is to identify cytokines related to the cellular immune response as well as blood brain barrier integrity and oxidative stress.MethodsWe performed a molecular characterization of cellular immune response and oxidative stress in serum from ...

PubMed Central

160
Serum and CSF N-acetyl aspartate levels differ in multiple sclerosis and neuromyelitis optica.
2011-05-27

Background The identification of biomarkers able to improve the differential diagnosis between multiple sclerosis (MS) and neuromyelitis optica (NMO) is challenging because of a different prognosis and response to treatment. Growing evidence indicates that brain and CSF N-acetyl aspartate (NAA) concentration is a useful marker for characterising different phases of axonal ...

PubMed

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161
Reappraisal of aquaporin-4 astrocytopathy in asian neuromyelitis optica and multiple sclerosis patients.
2011-02-14

Selective aquaporin-4 (AQP4) loss and vasculocentric complement and immunoglobulin deposition are characteristic of neuromyelitis optica (NMO). We recently reported extensive AQP4 loss in demyelinated and myelinated layers of Bal�'s lesions without perivascular immunoglobulin and complement deposition. We aimed to reappraise AQP4 expression patterns in NMO and multiple ...

PubMed

162
Prominent brainstem symptoms/signs in patients with neuromyelitis optica in a Taiwanese population.
2011-07-18

Neuromyelitis optica (NMO) is a severe demyelinating disease defined principally by its selective effect on the optic nerves and spinal cord. Contemporary diagnostic criteria require an absence of any clinical disease outside the optic nerve or spinal cord. However, we frequently encounter patients with NMO who have previously undetected symptomatic brainstem lesions. We ...

PubMed

163
Pearls: myelopathy.
2010-02-01

Both general neurologists and neurologists with a broad spectrum of subspecialty interests are often asked to evaluate patients with disorders of the spinal cord. Over the past decade, there have been significant advances in our understanding of a wide spectrum of immune-mediated, infectious, metabolic, hereditary, paraneoplastic, and compressive myelopathies. Advances have been made in the ...

PubMed

164
Optic neuritis in an ethnically diverse population: Higher risk of atypical cases in patients of African or African-Caribbean heritage.
2011-09-13

PURPOSE: To investigate the presence of an ethnicity bias within patients presenting with optic neuritis in London. DESIGN: Observational cross-sectional study. METHODS: The ethnicity profile of all patients attending a neuro-ophthalmology clinic in central London with acute optic neuritis over a 16month period (n=86) was studied. A comparison was made with the ethnicity profile of the population ...

PubMed

165
OPTICA: Our Path Together Initiating Cultural Access. Final Report.
2001-09-30

This final report describes the activities and outcomes of OPTICA (Our Path Together Initiating Cultural Access) programs. For each program an information sheet indicates the goal, total participation, status of the goal, and activities of the program. Programs included: (1) Hands On: ASL Creative Story Telling, a program that used children's books to introduce translating, to ...

ERIC Educational Resources Information Center

166
Neuromyelitis optica.
2010-05-01

OPINION STATEMENT: Neuromyelitis optica (NMO) or Devic's disease typically involves the optic nerves and the spinal cord and is most often relapsing. The pathogenesis is one of an acute inflammatory process targeting astrocytes and resulting in demyelination, as well as axonal injury. In a high proportion of recognized cases of NMO, there is a highly specific autoantibody ...

PubMed

167
Neuromyelitis optica (NMO)--an autoimmune disease of the central nervous system (CNS).
2010-09-29

In the past 10 years, neuromyelitis optica (NMO) has evolved from Devic's categorical clinical description into a broader disease spectrum. Serum IgG antibodies have been identified in NMO patients with the water channel aquaporin-4 (AQP4) as their main target antigen. AQP4 antibodies/NMO-IgG have been shown to be a highly specific and moderately sensitive serum biomarker for ...

PubMed

168
Low antioxidant status of serum uric acid, bilirubin and albumin in patients with neuromyelitis optica.
2011-07-30

Background:? Oxidative stress plays a central role in neuropathology of multiple sclerosis (MS). The patients with MS have low antioxidant status. Antioxidant therapy may represent an attractive treatment of MS. However, the relationship between neuromyelitis optica (NMO), a distinct nosologic entity or a form of MS, and antioxidant status has not fully been investigated. ...

PubMed

169
Influenza-associated Monophasic Neuromyelitis Optica.
2011-08-01

Neuromyelitis optica (NMO) is an inflammatory demyelinating disorder characterized by optic neuritis and acute myelitis. A parainfectious pathogenesis may play a partial role in the development of this disorder. Several viral infections are known to cause NMO. Here we report the case of a 15-year-old girl diagnosed with postinfluenza monophasic NMO. The patient developed ...

PubMed

170
HLA-DRB association in neuromyelitis optica is different from that observed in multiple sclerosis.
2009-12-07

Until recently, neuromyelitis optica (NMO) was considered to be a sub-type of multiple sclerosis (MS), which has a strong predilection for Caucasian populations, whereas NMO is more frequent in non-Caucasian individuals. The objective of this study was to compare the HLA-DRB profile in Brazilian Mulatto patients with NMO spectrum disorders (NMOSDs) with that observed for ...

PubMed

171
HLA, PTPN22 and PD-1 associations as markers of autoimmunity in neuromyelitis optica.
2011-09-01

Background: Neuromyelitis optica (NMO) is a disease with autoimmune characteristics. A genetic autoimmune dependency for NMO has not been clarified in detail. Objective: To investigate immunogenetic aspects of NMO. Methods: Forty-one patients with NMO and 42 patients with multiple sclerosis (MS) were diagnosed in a population-based Caucasian cohort. HLA DQA1, DQB1, and DRB1 ...

PubMed

172
Genetic analysis of aquaporin-4 in neuromyelitis optica.
2011-09-01

OBJECTIVE:Autoantibodies to aquaporin-4 (AQP4) are specific and pathogenic for neuromyelitis optica (NMO). Therefore, we evaluated whether AQP4 single-nucleotide polymorphisms (SNPs) are associated with susceptibility to NMO or whether mutations that potentially alter AQP4 structure or expression are present in some patients. METHODS:We genotyped 8 AQP4 SNPs chosen based on ...

PubMed

173
Frequency and syndrome specificity of antibodies to aquaporin-4 in neurological patients with rheumatic disorders.
2011-05-04

Background: A new autoantibody (termed NMO-IgG, or AQP4-Ab) has recently been described in patients with neuromyelitis optica (NMO) and its formes frustes, longitudinally extensive transverse myelitis (LETM) and recurrent optic neuritis (rON). However, AQP4-Ab has been found also in patients with co-existing rheumatic diseases such as systemic lupus erythematosus (SLE) or ...

PubMed

174
Cognitive Impairment and Whole Brain Diffusion in Patients with Neuromyelitis Optica after Acute Relapse
2011-10-01

The objective of this study investigated cognitive impairments and their correlations with fractional anisotropy (FA) and mean diffusivity (MD) in patients with neuromyelitis optica (NMO) without visible lesions on conventional brain MRI during acute relapse. Twenty one patients with NMO and 21 normal control subjects received several cognitive tests to assess cognitive ...

ERIC Educational Resources Information Center

175
Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance
2010-09-08

BackgroundIn 70-80% of cases, neuromyelitis optica (NMO) is associated with highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG). Recent evidence strongly suggests that AQP4-Ab are directly involved in the immunopathogenesis of NMO.ObjectiveTo assess the frequency, syndrome specificity, diagnostic relevance, and origin of cerebrospinal fluid (CSF) ...

PubMed Central

176
Brain abnormalities as an initial manifestation of neuromyelitis optica spectrum disorder.
2011-05-04

Background: Although brain abnormalities are being recognized more frequently in patients with neuromyelitis optica spectrum disorder (NMOSD), most brain lesions in previous reports have accompanied pre-existing NMOSD. Here, we describe clinical and imaging characteristics of patients with NMOSD who presented with brain symptoms as their first manifestation of the condition. ...

PubMed

177
Aquaporin-4: orthogonal array assembly, CNS functions, and role in neuromyelitis optica.
2011-05-09

Aquaporin-4 (AQP4) is a water-selective transporter expressed in astrocytes throughout the central nervous system, as well as in kidney, lung, stomach and skeletal muscle. The two AQP4 isoforms produced by alternative spicing, M1 and M23 AQP4, form heterotetramers that assemble in cell plasma membranes in supramolecular structures called orthogonal arrays of particles (OAPs). Phenotype analysis of ...

PubMed

178
Aquaporin-4 Mz isoform: brain expression, supramolecular assembly and neuromyelitis optica antibody binding.
2011-04-12

Water channel aquaporin-4 (AQP4) is expressed in astrocytes throughout brain and spinal cord. Two major AQP4 isoforms are expressed, M1 and M23, having different translation initiation sites. A longer isoform (Mz) has been reported in rat with translation initiation 126-bp upstream from that of M1. By immunoblot analysis of SDS and native gels probed with a C-terminus anti-AQP4 antibody, Mz was ...

PubMed

179
Anti-aquaporin-4 antibodies in Devic�s neuromyelitis optica: therapeutic implications
2010-09-01

Devic�s neuromyelitis optica (DNMO) is a demyelinating and inflammatory disease of the central nervous system (CNS) essentially restricted to the spinal cord and the optic nerves. It is a rare disorder with a prevalence estimated at less than 1/100,000 in Western countries. Since the first description by Eug�ne Devic in 1894, the relationship between DNMO and multiple ...

PubMed Central

180
Anti-aquaporin-4 antibodies in Devic's neuromyelitis optica: therapeutic implications.
2010-09-01

Devic's neuromyelitis optica (DNMO) is a demyelinating and inflammatory disease of the central nervous system (CNS) essentially restricted to the spinal cord and the optic nerves. It is a rare disorder with a prevalence estimated at less than 1/100,000 in Western countries. Since the first description by Eug�ne Devic in 1894, the relationship between DNMO and multiple ...

PubMed

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181
Abnormal baseline brain activity in patients with neuromyelitis optica: A resting-state fMRI study.
2010-05-31

PURPOSE: Recent immunopathologic and MRI findings suggest that tissue damage in neuromyelitis optica (NMO) is not limited to spinal cord and optic nerve, but also in brain. Baseline brain activity can reveal the brain functional changes to the tissue damages and give clues to the pathophysiology of NMO, however, it has never been explored by resting-state functional MRI ...

PubMed

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