... The plasma Cmax values for males ... extensive, with drug derived radioactivity ... RADIOACTIVITY, ABSORPTION, DRUGS, INGESTION(PHYSIOLOGY ...
DTIC Science & Technology
... 42 VII. ABSORPTION, DISTRIBUTION, BIOTRANSFORMATION, EXCRETION AND BIODEGRADATION OF TNT ..... ... 83 1. Absorption ..... ...
This review discusses recent literature on the chemical and physiological factors that result in the absorption, distribution, and excretion of aluminum in mammals, with particular regard to gastrointestinal absorption and speciation in plasma. umans encounter aluminum, a ubiquit...
EPA Science Inventory
...handled in the body and includes absorption, tissue distribution, biotransformation...and excretion. (3) Percent absorption means 100 times the ratio...means the study of the rates of absorption, tissue distribution,...
Code of Federal Regulations, 2011
Contents: Problems of analysis; Occurrence, possible routes of exposure and daily intake; Uptake and absorption; Transport, distribution and excretion of cadmium in animals; Transport distribution and excretion of cadmium in normal and exposed human being...
National Technical Information Service (NTIS)
... Accession Number : AD0676134. Title : ABSORPTION AND EXCRETION OF MERCURY IN DENTAL PERSONNEL: PRELIMINARY STUDY. ...
A multi-sector international group of government, academic, and industry scientists has developed a proposal for an improved testing scheme for assessing the safety of crop protection chemicals. Incorporation of pharmacokinetic studies describing the absorption, distribution, me...
The purposes of the research supported under this contract are to determine the toxicity of two members of the tricothercene mycotoxins, (anguidine, (DAS) and nivalenol) including their gross and microscopic effects; absorption, distribution and excretion...
The purposes of the research supported under this contract are to determine the toxicity of two members of the tricothecene mycotoxins, (anguidine, (das) and nivalenol) including their gross and microscopic effects; absorption, distribution and excretion ...
... derived drug product made from pig tissue (porcine intestinal mucosa ... These factors can alter the absorption, distribution, metabolism, excretion, and ...
Center for Drug Evaluation (CDER)
... Radiation Safety Officer: ... to maintain -10 to -30°C, protected from light (see protocol ... previous samples, data from the Method B analysis for Female ...
... orbital lachrymal gland Level C: Harderian gland/adrenal gland Level D: thyroid Level E: brain and spinal cord ... Pharmacokinetics and blood levels ...
... For subjects with extensive prior nucleoside use, double boosted PIs (eg ... that might interfere with drug absorption, distribution, metabolism or excretion -Any ...
The datafile contains 3273 articles on the absorption, distribution, metabolism, and excretion of approximately 2600 chemicals for oral routes of administration in laboratory animals or in man. Both quantitative and qualitative studies were included. Extr...
The update brings the total coverage of the datafile to 4078 articles on the absorption, distribution, metabolism, and excretion of approximately 3000 chemicals for oral routes of administration in laboratory animals or in man. Both quantitative and quali...
The update for 1985-1987 covers 863 articles on the absorption, distribution, metabolism, and excretion of chemicals for oral routes of administration in laboratory animals or in humans. Quantitative and qualitative studies are included. Extracted data fi...
Absorption, distribution, metabolism and excretion were studied in rats following a single oral administration of N-cyclohexyl-2-benzothiazyl sulfenamide (CBS) at a dose of 250 mg/kg. About 65% and 24% of the dose were excreted into urine and feces, respectively, for 3 days after administration of labeled CBS ...
PubMed
The biotransformation of inorganic mercury to methylmercury in aquatic food chains has become recognized as a serious environmental hazard. The use of methylmercury as a seed preservative is another major source of environmental pollution by this organometallic contaminant. The present report embodies integrated observations on the uptake, distribution and ...
Energy Citations Database
... Absorption, distribution, metabolism, and excretion In experimental animals, AA is rapidly and extensively absorbed from the gastrointestinal tract following ...
Center for Food Safety and Applied Nutrition (CFSAN)
Aldicarb is used as a pesticide for nemotodes, mites, and ticks. The drinking water health advisory covers the following areas: the occurrence of the chemical in the enviroment; its environmental fate; the chemical's absorption, distribution and excretion...
Contents: Mercury's and mercury compounds' effects on humans (Absorption, Distribution, Excretion, Inhibition of enzymes, Toxicity); Effects on animals; Effects on plants; Effects on materials; Environmental air standards (Mercury and its inorganic compou...
In order to obtain information on the potential transport of ingested Pu and to gain additional information on Pu deposition patterns in ruminants, a series of metabolism studies with dairy cows were conducted. Results are presented on tissue uptake following oral $sup 238$Pu administration. (CH)
...or serum anti-SRBC IgM levels, respectively. 1 If absorption/distribution/metabolism/excretion (ADME) data are...respond because the antigen was accidentally injected into the intestinal tract. (B) The activity of each new batch of...
Code of Federal Regulations, 2010
Phenylmercuric acetate was give intravenously, intramuscularly, or per os to chicks, rats, and dogs. The compound is apparently absorbed unchanged. Metabolism in the body was fairly rapid, detectable amounts of phenylmercuric acetate occurring for only approximately 96 hours. Small amount were excreted in the urine. 12 references, 6 tables.
This study evaluated the absorption, distribution, and excretion of dimethyl cyclosiloxane fluids by the oral route in rats. Two Sprague Dawley rats were given a single oral gavage dose of the radiolabeled test substance at a dose of 600 mg/kg and placed ...
... of the effect of fat (vegetable oil) on the blood ... DOSAGE, EXCRETION, USSR, TRANSLATIONS, VEGETABLE OILS, DOSAGE, GASTROINTESTINAL ...
The absorption, distribution, and excretion of trichloroethylene, as well as the kinetics of formation and elimination of trichloroethanol (TCE) and trichloroacetic acid (TCA) were simulated by a mathematical model. The results of this model have been satisfactorily compared with those obtained experimentally from pulmonary elimination ...
PubMed Central
Disturbances in absorption, distribution, and excretion of various medicinal substances were studied in l80 to 200 g rats exposed to 500-r whole- body irradiation. The results showed different reactions to various medications. The penetration of sodium sulfacyl was faster in the blood and organs and ...
The report covers the general principles and mechanisms of absorption and excretion of all metals, but of heavy metals in particular. Information is included on accumulation and retention of toxic metals, with special emphasis on absorption, excretion, an...
