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1
An In Vitro Skin Equivalent for Evaluation of Skin Absorption of ...
2008-12-01

... Title : An In Vitro Skin Equivalent for Evaluation of Skin Absorption of Compounds. Descriptive Note : Conference paper. ...

DTIC Science & Technology

2
BASIC STUDIES IN PERCUTANEOUS ABSORPTION.
1965-12-01

... Descriptors : *SKIN(ANATOMY), *BIOLOGICAL ABSORPTION, BIOLOGICAL ABSORPTION, SKIN(ANATOMY), BIOCHEMISTRY, MEMBRANES ...

DTIC Science & Technology

3
The Absorption of Benzene through Human Skin,
1985-10-28

... based on the determination of phenol contents in urine and on the new direct chemical method for the designation of skin absorption of benzene ...

DTIC Science & Technology

4
Dermal Absorption Kinetics of Liquid ...
1995-03-01

... The potential for occupational or accidental skin exposure to chemicals requires a full understanding of chemical absorption through the skin. ...

DTIC Science & Technology

5
DOSE RESPONSE OF SKIN ABSORPTION IN YOUNG AND ...
1987-01-19

... Title : DOSE RESPONSE OF SKIN ABSORPTION IN YOUNG AND ADULT RATS. Descriptive Note : CONFERENCE PAPER. ...

DTIC Science & Technology

6
Comparison of Anatomical Characteristics of the Skin for ...
1995-12-01

... of the anatomical differences of skin in laboratory animals. This understanding is critical to facilitate extrapolation of chemical absorption in animals ...

DTIC Science & Technology

7
BASIC STUDIES IN PERCUTANEOUS ABSORPTION
1961-12-01

... normal skin. The permeability of skin from rats on diets deficient in vitamins A, B(6) and C was not altered. Skin permeability ...

DTIC Science & Technology

8
Quantitating the Percutaneous Absorption of Mechanistically ...
2004-05-03

... IN VIVO ANALYSIS, SKIN(ANATOMY), TOXICOLOGY, FUEL ADDITIVES, NAPHTHALENES, TRANSDERMAL ABSORPTION, DODECANE. ...

DTIC Science & Technology

9
Plasma Boundary Collisionless Absorption Effects in the ...
1979-10-01

... fields. The transverse field absorption is evaluated and the connection with the anomalous skin effect is indicated. The ...

DTIC Science & Technology

10
Percutaneous Absorption of Chemical Vapors
1985-05-01

... TRANSDERMAL ABSORPTION, PERMEABILITY, SYMPOSIA, TOXIC HAZARDS, RATS, VAPORS, HALOGENATED HYDROCARBONS, SKIN( ...

DTIC Science & Technology

11
PERCUTANEOUS ABSORPTION
1964-03-15

... Abstract : A summary is given of studies concerning various aspects of the absorption of biologically active substances through the human skin. ...

DTIC Science & Technology

12
Dermal Absorption of Dihalomethane Vapors,

... Descriptors : *VAPORS, *HALOGENATED HYDROCARBONS, *SKIN( ANATOMY), *BIOLOGICAL ABSORPTION, *METHANES, REPRINTS ...

DTIC Science & Technology

13
BASIC STUDIES IN PERCUTANEOUS ABSORPTION.
1964-12-01

... Descriptors : *SKIN(ANATOMY), *ORGANIC SOLVENTS, *LIPIDS, ABSORPTION, PENETRATION, PERMEABILITY, INTEGUMENTARY SYSTEM ...

DTIC Science & Technology

14
BASIC STUDIES IN PERCUTANEOUS ABSORPTION.
1964-06-01

... Descriptors : *SKIN(ANATOMY), *ORGANIC SOLVENTS, *LIPIDS, ABSORPTION, PENETRATION, PERMEABILITY, INTEGUMENTARY SYSTEM ...

DTIC Science & Technology

15
BASIC STUDIES IN PERCUTANEOUS ABSORPTION
1963-12-01

... Descriptors : *SKIN(ANATOMY), *TRANSDERMAL ABSORPTION, PERMEABILITY, VAPORS, ELECTRICAL CONDUCTIVITY, AMINES ...

DTIC Science & Technology

16
BASIC STUDIES IN PERCUTANEOUS ABSORPTION
1962-12-01

... Descriptors : *ABSORPTION, *BIOCHEMISTRY, *HISTOLOGY, *LIPIDS ... ANIMALS, PENETRATION, PHOSPHOLIPIDS, SKIN(ANATOMY), SOLVENT ...

DTIC Science & Technology

17
BASIC STUDIES IN PERCUTANEOUS ABSORPTION
1961-06-01

... Descriptors : *ABSORPTION, *SKIN(ANATOMY), BIOCHEMISTRY, BLOOD SERUM, CHEMICALS, CYTOCHEMISTRY, DIET, ENZYMES ...

DTIC Science & Technology

18
In Vitro Skin Equivalent for Evaluation of Skin Absorption of Compounds.
2008-01-01

Skin Equivalents (SE) or Human Skin Equivalents (HSEs) are skin substitutes that can serve as models for testing the skin permeability of agents from formulations, or for evaluation of formulations themselves on the skin. We have developed a collagen base...

National Technical Information Service (NTIS)

19
CUPRIC ION ABSORPTION THROUGH THE DENUDED ...
1970-05-01

... Descriptors : *COPPER COMPOUNDS, *SKIN(ANATOMY), BIOLOGICAL ABSORPTION, BIOLOGICAL ABSORPTION, EXCISION, WOUNDS AND ...

DTIC Science & Technology

20
Dermal Absorption of Comp B and CRB-12 in Isolated Rat ...
2000-09-01

... DERMAL ABSORPTION OF COMP B AND CRB-12 IN ISOLATED RAT SKIN ... Dermal Absorption of Comp B and CRB-12 in Isolated Rat Skin ...

DTIC Science & Technology

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21
Chemical Reactions and Molecular Association Effects in Skin. I. Techniques of Measuring Electronic Absorption Spectra.
1971-01-01

Simple techniques have been developed to measure the ultraviolet and visible electronic absorption spectra of skin. The methods utilize both dorsal thoracic and ear skin of albino rabbits. The procedure with intact skin involves mounting the sample on a c...

National Technical Information Service (NTIS)

22
Penetration of Gaseous I131 Through Human Skin,
1979-12-21

... IODINE, *RADIATION EFFECTS, USSR, PENETRATION, RADIATION ABSORPTION, TRANSLATIONS, SKIN(ANATOMY), RADIOACTIVE ...

DTIC Science & Technology

23
Overview of Interactions of Chemicals with the Skin
1985-05-01

... of mechanisms underlying some of the phenomena in environmental skin disease, information has been collected on percutaneous absorption of a ...

DTIC Science & Technology

24
Human Dermal Fibroblasts (Adult): Instructions for Initiation of ...
2002-04-01

... CRYOGENICS, ASSAYING, COUNTERMEASURES, SKIN(ANATOMY), TISSUE CULTURE, TRANSDERMAL ABSORPTION, SKIN TESTS. ...

DTIC Science & Technology

25
Feasibility of Human Skin Grafts on an Isolated But Accessible ...
1986-04-01

... Descriptors : *BIOLOGICAL ABSORPTION, *FLAPS(CONTROL SURFACES), *SKIN GRAFTS, ANIMALS, BLOOD CIRCULATION, BLOOD ...

DTIC Science & Technology

26
Feasibility of Human Skin Grafts on An Isolated But Accessible ...
1986-06-01

... Descriptors : *BIOLOGICAL ABSORPTION, *SKIN GRAFTS, VALIDATION, MODELS, RATS, HUMANS, TOXICITY, METABOLISM, PENETRATION ...

DTIC Science & Technology

27
Fabric/Skin Contact from Wearing the Army Battle Dress ...
1987-07-01

... of the wearer. Of concern is the leaching out of impregnants and their availability for skin absorption. Prediction of dose ...

DTIC Science & Technology

28
Evaluation of Barrier Skin Cream Effectiveness Against JP-8 ...
2009-04-01

... BARRIER COATINGS, *TEST AND EVALUATION, *EPIDERMIS, *ABSORPTION, *IRRITATION, *OINTMENTS, *SKIN(ANATOMY), *AVIATION ...

DTIC Science & Technology

29
Development of In Vitro Isolated Perfused Porcine Skin Flaps ...
1986-11-01

... Title : Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics. ...

DTIC Science & Technology

30
Development of In Vitro Isolated Perfused Porcine Skin Flaps ...
1985-11-01

... Title : Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics. ...

DTIC Science & Technology

31
Dermal Absorption of Chemicals From Evaporating Vehicle ...
1999-04-30

... PHYSIOLOGY), *JET ENGINE FUELS, *SKIN(ANATOMY), *ORGANIC CHEMISTRY, *SKIN DISEASES, *DERMATITIS, MATHEMATICAL MODELS ...

DTIC Science & Technology

32
Chemical Reactions and Molecular Association Effects in Skin ...
1971-03-01

... Abstract : Simple techniques have been developed to measure the ultraviolet and visible electronic absorption spectra of skin. ...

DTIC Science & Technology

33
BIOLOGICAL ASSAY METHODS FOR MOSQUITO REPELLENTS

... influence the outcome and interpretation of repellent bioassays. Skin-mediated effects comprise absorption and penetration of repellent on skin, but evaporation, ... ...

NBII National Biological Information Infrastructure

34
Assessment of Skin Penetration of Environmental ...
1994-04-13

... soil. Skin absorption measurements in the live pig for soil (4%) and compost (1%) confirmed in vitro findings. In summary ...

DTIC Science & Technology

35
Percutaneous Absorption of Chemical Vapors
1985-05-01

... 'JH-ve-- _rates of penetration of hydrazine vapor through the skin have not -:een quantitated As a precaution against skin absorption, the Air Force ...

DTIC Science & Technology

36
In Vitro and In Vivo Measurement of Percutaneous Penetration ...
1989-12-15

... Keywords: Skin absorption, Human, Guinea pig, Buccal absorption, Microcystin, Brevetoxin, Lyngbyatoxin A, RA 1, Skin(anatomy). ...

DTIC Science & Technology

37
DEPSCoR 99 Percutaneous Absorption, Skin Biophysics and ...
2003-07-16

... Accession Number : ADA417176. Title : DEPSCoR 99 Percutaneous Absorption, Skin Biophysics and Dermatotoxicity from JP-8 Jet Fuel. ...

DTIC Science & Technology

38
In vivo determination of the absorbance spectra of human skin
2002-09-01

This is a pilot study about optical properties of the yellow race skin on the base of the theory of the Kubelka-Munk. The physical model of light-transfer in skin tissue is analyzed, then a formula of light-absorption ratio of human skin is derived. Not only a method of the detection of optical ...

NASA Astrophysics Data System (ADS)

39
Formulations of Deet, Picaridin, and IR3535 Applied to Skin Repel Nymphs of the Lone Star Tick (Acari: Ixodidae) for 12 ...

... the subject of complaints about its feel on skin, absorption by skin, and as a plasticizer (Frances and Debboun 2007). ... ...

NBII National Biological Information Infrastructure

40
Stereselective Absorption of Permethrin Through Silastic ...
2001-03-01

... Title : Stereselective Absorption of Permethrin Through Silastic Membrane and Excised Porcine Skin In Vitro Flow Through Diffusion System. ...

DTIC Science & Technology

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41
Quantitating the Absorption, Partitioning and Toxicity of ...
2007-08-24

... membrane coated fiber (MCEG) array, for assessing physiochemical parameters related to hydrocarbon partitioning and absorption through skin. ...

DTIC Science & Technology

42
Percutaneous Absorption of Volatile Chemicals
1997-11-01

... These studies demonstrated dose-dependent absorption of CPFB and DCB in skin which was further modulated by concomitant exposure to vehicle ...

DTIC Science & Technology

43
Percutaneous Absorption of Chemical Mixtures Relevant to ...
2000-02-01

... BARRIERS, FLAPS(CONTROL SURFACES), MARKERS, ABSORPTION, JET ENGINE FUELS, SKIN(ANATOMY), ORGANOPHOSPHATES ...

DTIC Science & Technology

44
PERCUTANEOUS ABSORPTION OF TOXIC SUBSTANCES. 4 ...

... Title : PERCUTANEOUS ABSORPTION OF TOXIC SUBSTANCES. 4. PROTECTION OF THE SKIN FROM LIQUID CHEMICAL WARFARE AGENTS ...

DTIC Science & Technology

45
Modeling Chemical Absorption Through Membranes.
1999-03-01

... understanding of the absorption process by first modeling simple membranes such as butyl rubber, and extrapolating the results for rat skin to other ...

DTIC Science & Technology

46
In vitro Methodology for Percutaneous Absorption Studies
1985-05-01

... Abstract : The absorption through the skin of toxic compounds can be significant and must be considered when dermal contact occurs. ...

DTIC Science & Technology

47
In Vitro and In Vivo Measurement of Percutaneous Penetration ...
1989-01-19

... Keywords: Skin absorption; Human; Guinea pig; Buccal absorption; Microcystin; Brevetoxin; Lyngbyatoxin A; RAI. Descriptors ...

DTIC Science & Technology

48
THE EFFECTS OF NON-UNIFORM ABSORBTIVITY OF ...
1958-07-01

... ON THE TEMPERATURE RISE IN AN AIRCRAFT SKIN. ... NUCLEAR EXPLOSIONS, SURFACE TEMPERATURE, UNITED KINGDOM, ABSORPTION. ...

DTIC Science & Technology

49
Prediction & Assessment of Dermal Exposure
1998-08-31

... INFRARED SPECTROSCOPY, HAZARDS, TOXICITY, DAMAGE ASSESSMENT, KINETICS, ABSORPTION, SKIN(ANATOMY), DERMATOLOGY. ...

DTIC Science & Technology

50
PERCUTANEOUS ABSORPTION
1964-03-15

... Antimetbolites (5-fluoruracil, 6-mercaptopurine and aminopterin) were applied topically to the skin of rabbits to prevent hair growth. ...

DTIC Science & Technology

51
PERCUTANEOUS ABSORPTION
1963-03-15

... development of miliaria. In vivo studies of the existence of a reservoir in human keratin and its capacity. Descriptors : *SKIN ...

DTIC Science & Technology

52
CHEMICAL STUDIES IN CONNECTION WITH POTENTIAL ...
1966-08-31

... pathogenic or physical impairments inflicted through the skin. ... CHEMISTRY), MOLECULAR STRUCTURE, ABSORPTION SPECTRA, HYDROXIDES ...

DTIC Science & Technology

53
BIOASSAY FOR TESTING PROTECTIVE GLOVE ...
1984-07-01

... Title : BIOASSAY FOR TESTING PROTECTIVE GLOVE PERFORMANCE AGAINST SKIN ABSORPTION OF ORGANIC SOLVENTS. ...

DTIC Science & Technology

54
Model for quantifying absorption through abnormal skin
1986-02-01

Techniques are available for quantitatively studying factors governing absorption through normal skin (in vivo and in vitro) but relatively little is known about the permeability of abnormal skin. We have designed and evaluated an in vivo model for quantifying absorption through abnormal skin. ...

Energy Citations Database

55
In vitro dermal absorption of pyrethroid pesticides in human and rat skin

Dermal exposure to pyrethroid pesticides can occur during manufacture and application. This study examined the in vitro dermal absorption of pyrethroids using rat and human skin. Dermatomed skin from adult male Long Evans rats or human cadavers was mounted in flowthrough diffusi...

EPA Science Inventory

56
Melanin absorption spectroscopy: new method for noninvasive skin investigation and melanoma detection

Melanin absorption spectroscopy: new method for noninvasive skin investigation and melanoma between malignant melanoma and dysplastic nevi in vivo. These preliminary results are confirmed both to melanoma in situ and then to malignant mela- noma is reflected in the melanin absorption spectra. Our

E-print Network

57
Dermal Absorption Kinetics of Liquid Chloropentafluorobenzene (CPFB) and 1,2-Dichlorobenzene (DCB) in Rats and Guinea Pigs.
1995-01-01

The potential for occupational or accidental skin exposure to chemicals requires a full understanding of chemical absorption through the skin. To determine whether species differences in dermal absorption are due to physical and physiological dissimilarit...

National Technical Information Service (NTIS)

58
In vitro and in vivo percutaneous absorption of catechol.
2003-06-01

The Cosmetic Ingredient Review Expert Panel found insufficient data to conclude that catechol could be used safely in permanent hair dye products. Information was lacking on the extent of oxidation and skin absorption of remaining catechol. In vitro percutaneous absorption studies were conducted in human and rat ...

PubMed

59
A Model to Predict Human Skin Burns.
1974-01-01

A model to predict burns to human skin is discussed. The model uses a finite difference heat transfer technique to predict skin temperatures. The wavelength-dependent absorptance of the skin is considered. First and second degree burns are predicted, base...

National Technical Information Service (NTIS)

60
Elaboration de Modeles Cutanes, Animaux et Humains en Vue de l'Etude du Mecanisme de l'Absorption Percutanee: Application a l'Etude des Agressifs Cutanes et d'Agents de Protection (Development of Animal and Human Skin Models to Study the Mechanism of Percutaneous Absorption: Application to the Study of Skin Aggressants and Protective Agents).
1989-01-01

The object of the report was to develop methods to study the routes by which chemical substances penetrate the skin, to develop human skin models (skin cell cultures, reconstituted skin) and to use model molecules to validate the study of the absorption a...

National Technical Information Service (NTIS)

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61
SKIN AND SUBCUTANEOUS TEMPERATURE CHANGES ...
1964-10-01

... data; it is indicated that most of the radiation is absorbed in the first 0.05 0.15 mm of skin through combined effects of absorption and scattering. ...

DTIC Science & Technology

62
Injury Thresholds for Topical-Cream-Coated Skin of Hairless ...

... Abstract : The reflectance and absorption of the skin plays a vital role in determining how much radiation will be absorbed by human tissue. ...

DTIC Science & Technology

63
Injury Thresholds for Topical Cream-Coated Skin of Hairless ...
2006-06-01

... Abstract : The reflectance and absorption of the skin plays a vital role in determining how much radiation will be absorbed by human tissue. ...

DTIC Science & Technology

64
In vivo Fluorescence Spectroscopy of Nonmelanoma Skin Cancer¶

... normalize the emission spectra for apparent changes in absorption between tumor and normal skin. In the overlapping spectral regions emission spectra were ... ...

NBII National Biological Information Infrastructure

65
Feasibility of Human Skin Grafts on an Isolated but Accessible ...
1983-11-01

... of blood flow dynamics has been undertaken since blood flow is significantly related to rates of percutaneous absorption and skin responses to ...

DTIC Science & Technology

66
Fabrics Protect Sensitive Skin from UV Rays - NASA

Mar 2, 2011 ... Fabrics Protect Sensitive Skin from UV Rays ... which enhances fabric reflectivity and UV absorption with special chemical treatments added ...

NASA Website

67
Defense Occupational and Environmental Health Readiness ...
2009-07-01

... the top of this screen that are used to select the hazards associated with exposure routes of ingestions, inhalation, skin absorption, skin and/or eye ...

DTIC Science & Technology

68
An In Vitro Skin Equivalent for Evaluation of Skin Absorption of ...
2008-12-01

... and the increase in cell population was measured ... Results of cell attachment of human dermal fibroblasts ... out to quantify total cell populations in the ...

DTIC Science & Technology

69
Acute Dermal Toxicity of Diethyleneglycol Dinitrate (TEGDN) ...
1989-01-01

... IRRITATION, SURFACES, ETHYLENE, ANIMALS, DEATH, SKIN(ANATOMY), BIOLOGICAL ABSORPTION, RABBITS, SKIN(GENERAL), WINDING ...

DTIC Science & Technology

70
Percutaneous Absorption of Volatile Chemicals.
1997-01-01

The purpose of this project was to assess the percutaneous absorption of two volatile organic compounds, chloropentafluorobenzene (CPFB) and dichlorobenzene (DCB) in the isolated perfused porcine skin flap (IPPSF) model. An independent theoretical goal wa...

National Technical Information Service (NTIS)

71
Percutaneous Absorption of Chemical Mixtures Relevant to ...
2002-02-01

... cell studies showed a number of effects, some of which projected into the perfused skin results. Silastic uniformly overestimated absorption of both ...

DTIC Science & Technology

72
Miconazole/Clotrimazole and Pregnancy

... miconazole or clotrimazole likely results in a higher absorption of the medication into your system compared to skin, but absorption is still low. Will taking miconazole or clotrimazole ...

MedlinePLUS

73
Dermal Absorption of Modular Artillery Charge (XM232).
1998-01-01

... We used excised rat skin in static diffusion cells to investigate the dermal absorption of these components from the MACS in powdered form. ...

DTIC Science & Technology

74
Dermal Absorption of Modular Artillery Charge (XM231).
1998-02-01

... We used excised rat skin in static diffusion cells to investigate dermal absorption of Ml propellant in powdered form. No ...

DTIC Science & Technology

75
Dermal Absorption of JP-8 Jet Fuel and Its Components
1999-03-01

... 8 may cause irritation when the skin is exposed repeatedly or for prolonged periods, but whether systemic toxicity from dermal absorption of fuels ...

DTIC Science & Technology

76
Dermal Absorption of Comp B and CRB-12 in Isolated Rat ...
2000-09-01

... Accession Number : ADA453182. Title : Dermal Absorption of Comp B and CRB-12 in Isolated Rat Skin. Descriptive Note : Interim rept. ...

DTIC Science & Technology

77
ABSORPTION OF RADIOACTIVE IODINE (NaI131) AND ...
1963-05-31

... Title : ABSORPTION OF RADIOACTIVE IODINE (NaI131) AND STRONTIUM (Sr85(NO3)2) THROUGH NORMAL SKIN, FIRST, SECOND, THIRD ...

DTIC Science & Technology

78
(12) United States Patent - NASA Technical Reports Server

750 mu, are due to a superposition of skin absorption and fat. 5o and muscle scattering effects on the dye absorption. Short- ...

NASA Website

79
Stereselective Absorption of Permethrin Through Silastic Membrane and Excised Porcine Skin In Vitro Flow Through Diffusion System.
2001-01-01

This is an abstract concerning: Stereselective Absorption of Permethrin Through Silastic Membrane and Excised Porcine Skin In Vitro Flow Through Diffusion System.

National Technical Information Service (NTIS)

80
Development of In vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics.
1985-01-01

This report describes an in vitro alternative animal model for dermatology and cutaneous toxicology. An anatomically intact, viable, isolated perfused skin preparation would be a useful model for studying percutaneous drug absorption because venous and ar...

National Technical Information Service (NTIS)

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81
Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics.
1986-01-01

Interspecies comparisons of cutaneous anatomy and physiology suggest that the weanling pig is a suitable surrogate for human skin; however, very few investigations of percutaneous absorption phenomena have been conducted in pigs. This study examined the r...

National Technical Information Service (NTIS)

82
Toxicokinetic Principles in Relation to Percutaneous ...

... Descriptors : *Toxicity, Dosage, Response(Biology), Kinetics, Skin(Anatomy), Biological absorption, Anatomical models, Physiology, Reprints. ...

DTIC Science & Technology

83
Telecon - Leachable in stopper, October 15, 2009 - Menveo

... standards. However, --b(4)---- is, as it was reported by OSHA, harmful by ingestion, toxic by skin absorption, and an irritant. ...

Center for Biologics Evaluation and Research (CBER)

84
TOXIC HAZARDS ASSOCIATED WITH PYROTECHNIC ...
1963-11-01

... COLORED SMOKES, SMOKE BOMBS, PARACHUTE FLARES, AIRCRAFT FLARES, BIOLOGICAL ABSORPTION, SKIN(ANATOMY), WOUNDS ...

DTIC Science & Technology

85
Supporting Measurements

Jan 9, 2008 ... and aerosol absorption over land and over sea, for .... pressurized skin of the aircraft. Only operational constraints are to close ...

NASA Website

86
QUANTITATIVE STUDIES ON THE EFFECTS OF NON ...
1951-05-11

... II. THE ABSORPTION OF HUMAN SKIN BETWEEN 440 AND 1000 mu FOR BLACK BODY RADIATION AT VARIOUS COLOR TEMPERATURES,. ...

DTIC Science & Technology

87
Percutaneous Toxicokinetics of Hydrazine and H-70 in the ...
1981-02-01

... Descriptors : *HYDRAZINES, *TOXICITY, SKIN(ANATOMY), DOGS, BIOLOGICAL ABSORPTION, RABBITS, HALF LIFE. ...

DTIC Science & Technology

88
Optical Spectroscopy and Multiphoton Imaging for the ...
2005-09-01

... effects of skin absorption and scattering in the quantification of the ... Intestinal and extra-intestinal tumor multiplicities in the Apc 1638N mouse model ...

DTIC Science & Technology

89
Mometasone Topical

... pants on the child. They can increase the absorption of mometasone through the skin, which can cause harmful effects.Do not apply ...

MedlinePLUS

90
Models of Heat Dissipation in a Homogeneous Solid.
1971-11-18

... MATHEMATICAL MODELS, THERMAL DIFFUSION, LASERS, THERMAL CONDUCTIVITY, ABSORPTION, SKIN(ANATOMY), TEMPERATURE ...

DTIC Science & Technology

91
Learn About Spacesuits - NASA

The pieces of the suit interlock so that none of the spacewalker's skin is exposed to .... diapers with extra absorption material under their spacesuits. ...

NASA Website

92
Gordon Conference on 'Barrier Function of Mammalian Skin' ...
1990-12-17

... IN VITRO PERCUTANEOUS ABSORPTION AND METABOLISM OF BENZOIC ACID, P- AMINOBENZOIC ACID (PABA) AND BENZOCAINE IN THE ...

DTIC Science & Technology

93
Experimental Characterization of Near-Infrared Laser Energy ...
2007-03-01

... LASERS, THICKNESS, COMPUTATIONS, IMPACT, HAZARDS, SAMPLING, ABSORPTION, ENERGY ABSORBERS, SKIN(ANATOMY), NEAR ...

DTIC Science & Technology

94
Evaluation of Calibration Parameters and Performance of the ...
1994-08-01

... CALIBRATION, *EXPOSURE(PHYSIOLOGY), *SKIN(ANATOMY), IMPACT ... CIVILIAN PERSONNEL, ABSORPTION, VAPOR PRESSURE, VIDEO ...

DTIC Science & Technology

95
Development of In Vitro Isolated Perfused Porcine Skin Flaps ...
1987-06-30

... development of transdermal drug delivery systems may be ... and percutaneous drug absorption ... CHEMICALS, METABOLISM, DRUGS, TOXICOLOGY ...

DTIC Science & Technology

96
Development and Implementation of a Scrub Habitat Compensation ...

primarily dead grass and bare ground resulting from herbicide treatment, and .... the gopher frog through skin absorption of herbicides. ...

NASA Website

97
Dermal Penetration and Distribution of 14C-Labeled ...

... Abstract : The insecticide permethrin was assessed for skin absorption potential in rabbits and dogs following a single application. ...

DTIC Science & Technology

98
An In Vivo Rodent Model for Identifying and Characterizing Acaricides

... be influenced by localized compound metabolism on the skin, compound absorption with subsequent systemic activity in the rat, or ... ...

NBII National Biological Information Infrastructure

99
Acute Toxicity Preliminary Assessment of the Relative Toxicity ...
1992-02-01

... Descriptors : *TOXICITY, *CONTAMINATION, *PENTANES, ABSORPTION, SKIN(ANATOMY), TOXICOLOGY. Subject Categories : TOXICOLOGY. ...

DTIC Science & Technology

100
A Direct in vivo Method for Studying the Percutaneous ...
1985-05-01

... Descriptors : *TOXICOLOGY, *TOXIC AGENTS, *ABSORPTION, *SKIN( ANATOMY), IN VIVO ANALYSIS, INJECTION, NEEDLES, PERMEABILITY ...

DTIC Science & Technology

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101
Chromosomal Changes in the Chinese Hamster Following Skin Exposure to Tritiated Luminous Compounds.
1967-01-01

The present study has investigated the possibility of chromosomal damage following skin absorption of tritium from luminous compounds in the Chinese hamster. The following conclusions were reached: Tritium was absorbed through the skin of Chinese hamsters...

National Technical Information Service (NTIS)

102
Transfollicular percutaneous absorption. Skin model for quantitative studies.
1988-01-01

Theoretically percutaneous absorption comprises two components: the transepidermal route and the transappendageal route, so-called 'shunt' diffusion. The relative importance of 'shunt' diffusion was investigated with a model of appendage-free skin. After treatment with 60 degrees C water for exactly 1 min, hairless dorsal rat skin ...

PubMed

103
Skin optics
1989-12-01

Quantitative dosimetry in the treatment of skin disorders with (laser) light requires information on propagation of light in the skin related to the optical properties of the individual skin layers. This involves the solution of the integro-differential equation of radiative transfer in a model representing skin ...

Energy Citations Database

104
In vitro and in vivo percutaneous absorption of retinol from cosmetic formulations: Significance of the skin reservoir and prediction of systemic absorption
2008-08-15

The percutaneous absorption of retinol (Vitamin A) from cosmetic formulations was studied to predict systemic absorption and to understand the significance of the skin reservoir in in vitro absorption studies. Viable skin from fuzzy rat or human subjects was assembled in flow-through diffusion ...

Energy Citations Database

105
In vitro skin penetration of fragrances: Trapping the evaporated material can enhance the dermal absorption of volatile chemicals.
2011-03-30

This study compared the evaporation and skin absorption profiles of four fragrance chemicals in in vitro skin penetration studies performed in conditions of airflows of low velocity with and without trapping of the evaporated volatiles. The presence of a trapping chamber above the skin surface slowed down the ...

PubMed

106
ABSORPTION OF NaI$sup 131$ THROUGH RAT SKIN AFTER X-IRRADIATION
1962-01-01

Irradiation of male rats with 400 to 2000 r x rays results in a marked delay of absorption. After irradiation with 10,000 r an increase of absorption could be observed. (Gmelin Inst.)

Energy Citations Database

107
Estimation of the spectral absorption of light by components of human skin
2009-01-01

The spectra of the absorption coefficients of external radiation by basic chromophores of human skin, such as melanin, basic tissue, and blood (including oxy- and deoxyhemoglobin), are studied in the wavelength range of 300-1000 nm. For estimates, analytical methods of the theory of light transfer are used, which take into account the multilayer structure ...

NASA Astrophysics Data System (ADS)

108
Influence of pressure on the photo-thermal effects of porcine skin
2007-10-01

Intense pulsed light system in combination with contact cooling is a useful tool for treating photodamaged skin. It can emit broadband light, and target different kind of pigment in skin. But the pressure on skin often influences the temperature field distribution inside the skin when the treatment head contacts ...

NASA Astrophysics Data System (ADS)

109
Percutaneous absorption and skin decontamination of PCBs: In vitro studies with human skin and in vivo studies in the rhesus monkey
1990-12-01

Knowledge of the entry of polychlorinated biphenyls through the skin into the body and subsequent disposition aids estimation of potential for human health hazard. (14C)Aroclor 1242 and (14C)Aroclor 1254 were separately administered intravenously and topically to rhesus monkeys. Following iv administration, 30-d excretion was 39.4 +/- 5.9% urine and 16.1 +/- 0.8% feces (total ...

Energy Citations Database

110
Determination of chromophore concentrations from spatially resolved skin measurements
2011-06-01

Chromophore concentrations from skin contain information about the blood parameters, for example total hemoglobin content or antioxidant status of the skin. Deviations from the normal values of the concentrations may indicate pathologies. As the chromophore concentrations are determined from skin absorption ...

NASA Astrophysics Data System (ADS)

111
Study of surfactant-skin interactions by skin impedance measurements.
2011-09-17

The stratum corneum (SC) plays a very critical physiological role as skin barrier in regulating water loss through the skin and protects the body from a wide range of physical and chemical exogenous insults. Surfactant-containing formulations can induce skin damage and irritation owing to surfactant absorption and ...

PubMed

112
IN VITRO DERMAL ABSORPTION OF PYRETHROID PESTICIDES IN RAT AND HUMAN SKIN

Pyrethriods are a class of neurotoxic pesticides and their use may lead to dermal exposure. This study examined the in vitro dermal absorption of pyrethroids in rat and human skin. Dorsal skin removed from adult male LD rats (hair clipped 24 h previously) was dermatomed and mou...

EPA Science Inventory

113
Percutaneous absorption-enhancing activity of urea derivatives.
1991-03-01

The effect of urea and urea derivatives on the percutaneous absorption of salicylic acid and sodium salicylate through the skin of rabbit from petrolatum ointment was investigated. It was found that addition of urea or urea derivatives to the ointment base significantly increased the percutaneous absorption of the drugs in proportion ...

PubMed

114
Percutaneous penetration and metabolism of 2-ethoxyethanol.
2002-04-15

Percutaneous absorption and cutaneous metabolism of 2-ethoxyethanol were assessed in vivo and with an in vitro flow-through diffusion system. Topical application of undiluted (14)C-ethoxyethanol to occluded rat skin in vivo resulted in 25% of the dose being absorbed after 24 h. The major routes of excretion included the urine (15%), expiration as carbon ...

PubMed

115
Skin Absorption Pharmacology of Topical Skin Protectant ICD Number 2289.
1997-01-01

Attenuated Total Reflectance (ATR) Fourier Transform-Infrared (FTIR) spectroscopy was used to determine the effectiveness of washing Topical Skin Protectant (TSP) ICD Number 2289 from the skin of male euthymic hairless guinea pigs 24 hours after TSP appli...

National Technical Information Service (NTIS)

116
In vitro absorption of some o-phthalate diesters through human and rat skin
1987-10-01

The absorption of undiluted phthalate diesters (dimethyl phthalate (DMP), diethylphthalate (DEP), dibutyl phthalate (DBP) and di-(2-ethylhexyl)phthalate (DEHP)) has been measured in vitro through human and rat epidermal membranes. Epidermal membranes were set up in glass diffusion cells and their permeability to tritiated water measured to establish the integrity of the ...

Energy Citations Database

117
Sunscreen effects in skin analyzed by photoacoustic spectroscopy
2005-06-01

In this work, photoacoustic spectroscopy (PAS) was employed to characterize samples of commercially available sunscreen (SPF15) and the system formed by sunscreen plus skin (topically applied sunscreen). Measurements were performed at 70Hz, in the wavelength range that corresponds to most of the ultraviolet (UV) radiation that reaches Earth. The absorption ...

NASA Astrophysics Data System (ADS)

118
Transdermal absorption of radioprotectors using permeation-enhancing vehicles
1990-02-01

Radioprotectors are not currently used clinically due to concerns regarding toxicity and uncertainties regarding tumor protection. Topical radioprotection of skin might find clinical applications with protectors such as WR-2721, but laboratory studies in which protectors have been applied in water have not been promising. We have studied the absorption of ...

Energy Citations Database

119
The Absorption of Monomethylhydrazine Through Canine Skin.
1968-01-01

Graded doses of monomethylhydrazine (MMH) were applied to a 300 sq cm area of the shaved chest of anesthetized dogs. The area of skin to which the MMH was applied was reddened within 5 min., and the color progressively changed to deep red, then to yellow-...

National Technical Information Service (NTIS)

120
Physiologically-Based Pharmacokinetic Modeling of Skin Absorption Using Dermal Subcompartments.
1995-01-01

Dermal penetration of chemicals and drugs is important to both toxicologists and pharmacologists. Drug developers try to enhance and environmental professionals try to limit penetration of chemicals through the skin. Both can use predictive biologically-b...

National Technical Information Service (NTIS)

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121
Improved Methods for Dermal Exposure Estimation.
2008-01-01

A mathematical model that closely mimics percutaneous absorption, tissue concentrations and clearance in human skin in vivo was developed. Unique features of this model include an unprecedented level of detail in relating solute transport to the skin micr...

National Technical Information Service (NTIS)

122
Development of In vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics.
1987-01-01

This report describes the development of a novel in vitro alternative animal model for use in dermatology and cutaneous toxicology. A single pedicle, axial pattern, island-tubed skin flap was created in crossbred Yorkshire weanling pigs in one surgical pr...

National Technical Information Service (NTIS)

123
Absorption of Cyclotron Radiation in Skin Layer in Araks Experiment (Abstract Only).
1987-01-01

Analytical and numerical calculations are presented for the heating of the plasma electrons during very low frequency (VLF) propagation in the skin layer (omega approx. equal to Omega sub e) in the Araks experiment. The experiment involved the injection o...

National Technical Information Service (NTIS)

124
Experimental methods for determining permethrin dermal absorption.
2011-01-01

The objectives of this study were to (1) determine the percutaneous absorption of radiolabeled permethrin and piperonyl butoxide (PBO) in vivo in rats and in vitro to permit a calculation of the ratio of in vitro to in vivo values, and (2) test a method of estimating in vivo human absorption. Carbon-14 labeled permethrin in ethanol solution was applied to ...

PubMed

125
Thermal effusivity of human skin by photoacoustic technique
2000-05-01

In this work, we show a particular setup, which is based on the conventional photoacoustic cell, to measure thermal effusivity of human skin in-vivo and in-situ. We measure the changes of thermal effusivity due to the absorption of sunscreen into the skin and these values are compared with those from an adjacent sample of clean ...

NASA Astrophysics Data System (ADS)

126
Terahertz spectroscopy of human skin constituents in suspension
2008-03-01

Continuous wave terahertz imaging has the potential to offer a non-invasive medical imaging modality for detecting different types of human cancers. The aim of this study was to identify frequencies of interest for continuous wave terahertz imaging of skin cancer. The absorption characteristics of water, collagen, and elastin were studied in the range ...

NASA Astrophysics Data System (ADS)

127
SPECTROPHOTOMETRIC REMISSION MEASUREMENTS ON HUMAN SKIN IN THE REGION OF 220 TO 2500 nm
1962-04-01

Measurements of the spectral skin remission, limited to the diffuse portion of the back scattering shows very well the details of the absorption- spectrum of deeper skin layers Technical problems about measurement of remission are discussed. The modification of the remission spectrum by the plgment of Europeans and Negroes is ...

Energy Citations Database

128
Percutaneous penetration and metabolism of 2-butoxyethanol.
2004-09-29

2-Butoxyethanol (2-BE) is widely used as an industrial solvent, which may result in human dermal exposure within the workplace. This study compares in vivo and in vitro skin absorption of 2-BE using similar application regimes and determines the potential of skin to metabolise this chemical prior to entering the systemic blood ...

PubMed

129
An analytical solution for percutaneous drug absorption: application and removal of the vehicle.
2005-10-01

The methods of Laplace transform were used to solve a mathematical model developed for percutaneous drug absorption. This model includes application and removal of the vehicle from the skin. A system of two linear partial differential equations was solved for the application period. The concentration of the medicinal agent in the skin ...

PubMed

130
Sensitivity of light interaction computer model to the absorption properties of skin
2011-06-01

Light based treatments offer major benefits to patients. Many of the light based treatments or diagnostic techniques need to penetrate the skin to reach the site of interest. Human skin is a highly scattering medium and the melanin in the epidermal layer of the skin is a major absorber of light in the visible and near infrared ...

NASA Astrophysics Data System (ADS)

131
Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases.
2006-07-19

There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals. This case report emphasizes the relevance of dermal absorption of the aromatic amine ortho-toluidine considering four workers with different ...

PubMed

132
Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases
2006-07-19

There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals. This case report emphasizes the relevance of dermal absorption of the aromatic amine ortho-toluidine considering four workers with different ...

PubMed Central

133
Use of various models for in vitro percutaneous absorption studies of ultraviolet filters.
2009-08-01

BACKGROUND: The percutaneous absorption test aims to estimate the passage of a substance across the skin. The absorption process can be described in three steps: (a) penetration of a substance into the skin layer, followed by (b) penetration from one layer into another (permeation) and finally (c) resorption into ...

PubMed

134
Use of a Sustained Release Preparation of Clotrimazole to Treat Dermatophytosis in a Siamang (Hylobates syndactylus)

... S. and E. Horlock. 1978. Effect of repeated skin application on percutaneous absorption of salicylic acid. J. Pharm. Sci 67:121685� ... ...

NBII National Biological Information Infrastructure

135
Terahertz Spectroscopy of Intrinsic Biomarkers for Non ...

... The absorption characteristics of skin constituents were studied between 20 and 100 cm-1 (0.6 THz - 3 THz). Terahertz ...

DTIC Science & Technology

136
PODAAC Datasets - ECHO

Jun 17, 2010... spectrum where little or no atmospheric absorption occurs. ..... In order to produce a foundation SST estimate, the AATSR skin SST data ...

NASA Website

137
Nonlinear skin effect in a dense plasma
1980-10-01

The nonlinear boundary-value problem for resonance absorption of a powerful electromagnetic wave in a sypatially bounded plasma is solved.(AIP)

Energy Citations Database

138
NIH.R1-5

Tissues of fetal and term animals were assayed for calcium content by atomic absorption spectrophotometry. Transport studies of water across whole skin and ...

NASA Website

139
MANUFACTURING METHODS FOR ORGANIC AND ...
1968-05-01

... absorption; determine thermal, electrical, and mechanical properties of foam sandwich composites (PBI/glass inner and outer skins, PBI and/or a ...

DTIC Science & Technology

140
In Vitro and In Vivo Measurement of Percutaneous Penetration ...
1990-10-21

... TERMS (Continue on reverse if niecessary and identity by block number) FIELD GROUP 1SUB-GROUO ý%Skin absorption, human, guinea pig ...

DTIC Science & Technology

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141
Effects of Wearing Impermeable and Permeable Protective ...
2000-11-01

... Title : Effects of Wearing Impermeable and Permeable ... and WARM, skin and core temperatures were lower ... weight increase due to absorption of non ...

DTIC Science & Technology

142
Effect of Microgravity on Epidermal Development in the

Apr 21, 2011 ... Tissues of fetal and term animals were assayed for calcium content by atomic absorption spectrophotometry. Finally, transport studies of water across whole skin ...

NASA Website

143
ENERGY ABSORPTION BEHAVIOUR OF 3-D-WOVEN ...
1995-08-01

... THE WOVEN SKINS BY A Z-DIRECTIONAL PILE-FIBRE SYSTEM. ... INVESTIGATIONS OF THE ENERGY ABSORBING BEHAVIOUR OF THIS NEW ...

DTIC Science & Technology

144
Development of in vitro isolated perfused porcine skin flaps for study of percutaneous absorption of xenobiotics. Annual report, 30 September 1985-29 September 1986
1986-11-01

Interspecies comparisons of cutaneous anatomy and physiology suggest that the weanling pig is a suitable surrogate for human skin; however, very few investigations of percutaneous absorption phenomena have been conducted in pigs. This study examined the radiolabel excretion patterns after intravenous (IV) and topical administration of six /sup 14/C-labeled ...

Energy Citations Database

145
Detection of cloud-affected AIRS channels using an adjacent ... - NASA

conditions with background errors (background skin-temperature error of 2.3 K) ; .... These channels are primarily sensitive to CO2 absorption ...

NASA Website

146
Dermal Toxicity of T-2 Toxin in Guinea Pigs, Rats, and ...
1983-09-28

... possible species differences in their absorption through the skin or by ... lymphoid tissues and intestinal epithelieum were observed, with only mild ...

DTIC Science & Technology

147
Dermal Penetration of the Candidate Insect Repellent AI3 ...
1996-10-01

... Within the intended use of A13-37220 as a topical insect repellent, skin absorption in humans would be expected to be less than 8 percent of an ...

DTIC Science & Technology

148
Dermal Penetration and Distribution of 14C-Labeled ...
1983-04-01

... Pagination or Media Count : 15. Abstract : The skin absorption potential of paranitrophenol, a leather fungicide, was assessed in rabbits and dogs. ...

DTIC Science & Technology

149
Beta-Radiation Doses from Fallout Particles Deposited on the ...
1971-01-01

... Descriptors : *FALLOUT, BETA PARTICLES, BIOLOGICAL ABSORPTION, RADIATION DOSAGE, SKIN(ANATOMY), FALLOUT, RADIATION ...

DTIC Science & Technology

150
Association - NASA Technical Report Server (NTRS)

methemoglobinemia resulting in cyanosis. Both styrene and dimethylaniline can enter the bloodstream by either inhalation or absorption through the skinCZ3L ...

NASA Website

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