We describe a 77-year-old man with refractory gastric ulcer that worsened after Helicobacter pylori eradication therapy. Pathology showed marked infiltration of IgG4-positive plasma cells in the gastric lesions, which led us to suspect IgG4-related sclerosing disease. To the best of our knowledge, this is the first report of IgG4-related gastric ulcer without the main ...
PubMed Central
We describe 2 cases of IgG4-related disease with pleural effusion in elderly men. Both patients had elevated serum IgG4 levels, and the characteristics of their pleural effusion were similar. Patient 1 had pericardial effusion and retroperitoneal fibrosis, and a biopsy specimen from the pericardium showed infiltration of abundant IgG4-positive plasma cells ...
PubMed
The purpose of this study is to determine the relationship of ocular adnexal benign or reactive lymphoid hyperplasia, including orbital pseudotumor, with immunoglobulin G4 (IgG4)-related diseases. Medical charts of 9 consecutive patients with ocular adnexal benign lymphoid lesions, seen in the Department of Ophthalmology, Okayama University Hospital, were reviewed, and pathological sections were ...
IgG4-related disease is a distinct clinical entity, whose characteristic features are the following; Serum IgG4 is prominently elevated, IgG4-positive plasma cells infiltrate in involved tissues, various mass-forming lesions with fibrosis develop in a timely and spatial manner and the response to corticosteroids is prompt and good. IgG4-related diseases mainly target two ...
'Immunoglobulin G4 (IgG4)-related disease' is a new clinical concept of multi-organ diseases, with Mikulicz's disease (MD) being a clinical phenotype of IgG4-related disease. To clarify the clinical characteristics of respiratory involvement associated with IgG4-related MD, we retrospectively assessed 25 patients with MD, 11 (44%) of whom had allergic symptoms, and 7 (28%) of whom complained of ...
IgG4-related disease has been recognized as a systemic syndrome characterized by mass-forming lesions with lymphoplasmacytic infiltration and sclerosis. This disease has been identified in various sites, including the pancreas, retroperitoneum, lung, head, and neck. Herein we report a case of IgG4-related sclerosing mesenteritis. An 82-year-old woman was admitted to our hospital due to persistent ...
Inflammatory pseudotumors are lesions characterized by proliferation of fibroblasts/myofibroblasts with variable chronic inflammatory cell infiltration. Recent studies have suggested that inflammatory pseudotumor with abundant IgG4-positive plasma cells may be a unique entity associated with systemic IgG4-related sclerosing disease and should be ...
Autoimmune pancreatitis (AIP) shows a unique spectrum of histologic features and commonly presents with an abundant IgG4-positive (IgG4+) plasma cell infiltration. However, differentiating AIP from other mass lesions, particularly pancreatic cancer [invasive ductal carcinoma (IDC)] can be clinically challenging. In this study, we evaluated the validity of ...
IgG4-related sclerosing disease (IgG4-RSD) is a systemic one in which IgG4-positive plasma cells and T lymphocytes extensively infiltrate various organs. The clinical manifestations of the disease include autoimmune pancreatitis, sclerosing cholangitis, cholecystitis, sialodenitis, retroperitoneal fibrosis, tubulointestitial nephritis, interstitial pneumonia, prostatitis, ...
This case study describes a 58-year-old man with watery eyes, bilateral swelling of the ala nasi and submandibular glands, and a swollen right parotid gland. Computed tomography revealed mass-forming lesions in both nasolacrimal ducts, extending bilaterally to the lacrimal sac and inferior meatus in the nose. Pathologic investigation showed marked infiltrates of immunoglobulin 4 (IgG4)-positive ...
AimsTo report the clinicopathological characteristics of patients with ocular adnexal marginal zone B cell lymphoma (MZBL) with IgG4-positive plasma cells.Methods114 biopsy samples of ocular adnexal MZBLs were analysed. MZBLs with IgG4-positive plasma cells were included when the IgG4:IgG ratio was >40% (IgG4-related group). The serum levels of each ...
Thymic fibrosis in the absence of another primary thymic lesion, such as a neoplasm or cyst, is unusual. We identified 6 cases of primary extensive thymic fibrosis that developed in 3 men and 3 women, aged 28 to 60 years, mean 48 years. Patients had limited or no symptoms. Two patients had dyspnea and 1 had cough and hemoptysis. One female patient had myasthenia gravis. The lesions measured 3.5 to ...
Periarteritis, including periaortitis, is a systemic disorder characterized by an excessive fibroinflammatory reaction that can result in the compromise of great vessels and periarterial/periaortic structures. Recent studies have suggested that IgG4-related inflammation may play a role in chronic periaortitis. These pathologic conditions might represent a systemic disorder with fibrotic reaction ...
Dura-based marginal zone lymphomas represent an uncommon group of low-grade B-cell neoplasms, and literature regarding the clinical, histological and genetic profile of these tumors in the context of the newly described IgG4-related entities is lacking. We analyzed 32 dura-based marginal zone lymphomas identified in 27 females and 5 males ranging in age from 33-82 years (median 50). Morphologic ...
BACKGROUND: IgG4-related disease has attracted wide attention recently. It is characterized by a high level of serum IgG4 and dense infiltration of IgG4-positive plasma cells into multiple organs, with the kidney being one representative target. Although several sets of diagnostic criteria for autoimmune pancreatitis (AIP) are available and renal lesion is recognized as an ...
Background & AimsCorticosteroids are now widely accepted as a treatment for autoimmune pancreatitis (AIP). However, the molecular mechanism by which steroid treatment improves AIP remains largely unknown. The aim of this study was to elucidate cellular mechanisms by which corticosteroids improve both pancreatic exocrine function and histopathology in AIP.MethodsPancreatic exocrine function was ...
Purpose: To retrospectively evaluate computed tomographic (CT) findings of immunoglobulin G4 (IgG4)-related disease involving the vascular system. Materials and Methods: This study was approved by the institutional review board, and all patients included had consented to the use of their medical records for the purpose of research. The study consisted of 17 patients (16 men and one woman; age ...
IgG4-related disease has evolved from originally being recognized as a form of pancreatitis to encompass diseases of numerous organs including the hypophysis and one reported case of dural involvement. A search of the University of Virginia, Division of Neuropathology files for 10 years identified ten cases of unexplained lymphoplasmacytic meningeal inflammation that we then evaluated using ...
We report herein high-resolution computed tomography findings from a patient with IgG4-related pulmonary disease for the first time. The 61-year-old male patient complained of low-grade fever, dry mouth, and night sweats. He was diagnosed as having autoimmune pancreatitis, Sj�gren syndrome, and elevated serum IgG4. High-resolution computed tomography of the lungs showed dense alveolar ...
In a review of the literature concerning autoimmune pancreatitis we had special interest for the concept of IgG4-related pathology as a systemic disease with several clinical manifestations. In general, IgG4-positivity can not only be found in the pancreas, but also at the level of the kidneys, extrahepatic biliary ducts, gallbladder, lungs, salivary glands, lacrimal glands, retroperitoneal ...
Abundances are defined by the abund command par3. Ionization timescale in units of s cm. 3 . par4. Ionization timescale averaged plasma temperature (keV) ...
NASA Website
Identify non-equilibrium effects and the transition to thermal equilibrium. " Characterize abundances and study the FIP effect ...
plasma diagnostics, temperature, abundance, FIP. � transient events, jets, explosive events, flows, flares. � oscillations, waves ...
This single-page reading underlines how abundant plasmas are in the universe. The reading, which is the final page in a tutorial about the plasma phase of matter, points out that understanding plasma is central to understanding what happens in the universe. Through space technologies, researchers have been able to ...
NSDL National Science Digital Library
IgG4-related systemic disease is a recently described entity that can elude even the most astute diagnostician. Patients with the disease, characterized by the infiltration of polyclonal IgG4-positive plasmacytes, can present with single or multi-organ involvement. Manifestations include dacryoadenitis, sialadenitis, thyroiditis, pneumonitis, retroperitoneal fibrosis, pancreatitis, sclerosing ...
We report the results of abundant plasma protein depletion on the analysis of underivatized N-linked glycans derived from plasma proteins by nanoLC Fourier-transform ion cyclotron resonance mass spectrometry. N-linked glycan profiles were compared between plasma samples where the six most ...
Immunoaffinity depletion with antibodies to the top 7 or top 14 high abundance plasma proteins is used to enhance detection of lower abundance proteins in both shotgun and targeted proteomic analyses. We evaluated the effects of top 7/top 14 immunodepletion on the shotgun proteomic analysis of human plasma. Our ...
Tumor-derived, circulating proteins are potentially useful as biomarkers for detection of cancer, for monitoring of disease progression, regression and recurrence, and for assessment of therapeutic response. Here we interrogated how a protein's stability, cellular localization, and abundance affect its observability in blood by mass-spectrometry-based proteomics techniques. We ...
... 10^49 cm^(-3) keV^(-1) a[1] - minimum plasma temperature (keV) a[2] ... a[8] - Relative abundance for Argon a[9] - Relative abundance for He, C, N, O, ...
abundances of the trace elements (ie Li, Be, B, F, Na, P, Cl, K, Sc, Ti, V, Cr, Mn, Co, Cu, Zn) can be set using xset APEC_TRACE_ABUND. ...
We present new plasma diagnostics and abundances of a sample of planetary nebulae located in the Galactic bulge (168 objects), the Galactic inner disk (61 objects) and in the LMC (110 objects). (6 data files).
NASA Astrophysics Data System (ADS)
X-ray line emission from hot, low-density plasma in young supernova remnants is strongly enhanced by
NASA Technical Reports Server (NTRS)
Savin & Laming (2002) showed how errors in the atomic physics affected abundance measurements. XSPEC and Sherpa could include model errors. ...
In contrast, flare-accelerated ions have characteristic abundances produced by resonant wave-particle interactions in the flare plasma. ...
Primary inversions of accurately measured solar oscillation frequencies coupled with the equations of thermal equilibrium and other input physics, enable us to infer the temperature and hydrogen abundance profiles inside the Sun. These profiles also help in setting constraints on the input physics as well as on heavy element abundance in the solar core. ...
A new calculation of metastable and parent resolved effective ionization and recombination rate coefficients of ions in plasmas is presented. Metastable populations are shown to influence ion abundances and spectral emission.
Energy Citations Database
The local stability and the MHD (magnetohydrodynamic) propagation of linear waves in optically thin plasmas are analyzed. From Hurwitz's criteria the critical wave numbers for unstable disturbances are found. For the wave driven case, a dispersion relatio...
National Technical Information Service (NTIS)
The relative multiplicity abundance K/sup +//..pi../sup +/ and K/sup +//p/sup +/ arising in quark-gluon plasma formed in high energy nuclear collisions is determined. It is shown how these ratios assist in discriminating between various reaction channels.
This work is primarily concerned with the theoretical and experimental study of the molecular ion densities existing in plasmas produced in inert gases and their mixtures. The experimental investigations were accom plished through the use of a quadrupole ...
The Multispecies loop modeling project addresses the modeling of TRACE and SOHO observations as a plasma rather than a single fluid. In the single-fluid approximation the effects of heavy species are considered in an averaged sense. Further, loop abundances are usually taken to be uniform throughout the loop, in spite of observational evidence for ...
). The relative Table 1. Percent heavy isotopic abundance of selected amino acids isotopic abundance of selected amino acids and carbon in exhaled CO2 were monitored. An increase in the relative isotopic mass of serum of stable isotopes observed in the plasma amino acids and in exhaled breath 13 CO2 delta values. The exhaled
E-print Network
Studies of element abundances in stars are of fundamental interest for their impact in a wide astrophysical context, from our understanding of galactic chemistry and its evolution, to their effect on models of stellar interiors, to the influence of the composition of material in young stellar environments on the planet formation process. We review recent results of studies of ...
Solar energetic particles (SEPs) provide a measurement of coronal element abundances that is highly independent of the ionization states and temperature of the ions in the source plasma. The most complete measurements come from large 'gradual' events where ambient coronal plasma is swept up by the expanding shock wave from a coronal ...
Interest in the application of advanced proteomics technologies to human blood plasma- or serum-based clinical samples for the purpose of discovering disease biomarkers continues to grow; however, the enormous dynamic range of protein concentrations in these types of samples (often >10 orders of magnitude) represents a significant analytical challenge, particularly for ...
The detection of low-abundance protein disease biomarkers from human blood poses significant challenges due to the high dynamic range of protein concentrations that span more than 10 orders of magnitude, as well as the extreme complexity of the serum/plasma proteome. Therefore, experimental strategies that include the removal of ...
X-ray astronomy studies of thin, thermal plasmas in stellar coronas, supernova remnants, and clusters of galaxies are reviewed. Plasma diagnostics for density, temperature and elemental abundance, as well as for departures from ionization equilibrium are described. These were used in analyses of data from imaging and spectroscopic ...
Plasma is the most easily accessible source for biomarker discovery in clinical proteomics. However, identifying potential biomarkers from plasma is a challenge given the large dynamic range of proteins. The potential biomarkers in plasma are generally present at very low abundance levels and hence identification ...
Molecular biomarkers of early stage breast cancer may improve the sensitivity and specificity of diagnosis. Plasma biomarkers have additional value in that they can be monitored with minimal invasiveness. Plasma biomarker discovery by genome-wide proteomic methods is impeded by the wide dynamic range of protein abundance and the ...
The relative elemental abundances of iron, oxygen, magnesium, and neon in the solar corona are investigated with simultaneous broadband and spectral-line soft X-ray data. Coordinated observations of a solar active region were made by the American Science and Engineering High Resolution Soft X-Ray Imaging Sounding Rocket Payload, and by the X-ray Polychromator Flat Crystal ...
The model is suggested to describe dynamics of plasma parameters during high pressure gas injection. Model predicts fast decrease of electron and ion temperatures, electron beam generation, ion abundance and average ion charge, the rate of total radiation losses. It was found that the main reason for electron and ion temperature drop is energy exchange ...
Biosynthesis of glucans occurred in cell-free fractions isolated from onion stem (Allium cepa L.) enriched in either dictyosomes or plasma membranes. ?-1,3- and ?-1, 4-Glucans were synthesized in differing proportions and at different rates as the concentration of uridine diphosphoglucose or the proportion of dictyosomes or plasma membrane varied. At low ...
BackgroundTo date, the complexity of the plasma proteome exceeds the analytical capacity of conventional approaches to isolate lower abundance proteins that may prove to be informative biomarkers. Only complex multistep separation strategies have been able to detect a substantial number of low abundance proteins (<100 ng/ml). The ...
We carried out a detailed study of the Si, Fe and Ni abundances in the cool cores of a representative sample of local galaxy clusters using XMM-Newton data. We first evaluated the systematic errors on the abundance measurements that are related to the instruments, the plasma codes and the spectral modeling. We then used the Si/Fe and ...
Important clues to the chemical and dynamical history of elliptical galaxies are encoded in the abundances of heavy elements in the X-ray emitting plasma. We derive the hot ISM abundance pattern in a small sample of elliptical galaxies from analysis of Suzaku spectra, supported by analysis of co-spatial XMM-Newton spectra. We apply ...
I have studied the helium abundance in polar coronal holes and the fast solar wind using a time-dependent numerical model for the hydrogen-helium solar wind that spans the mid-to-upper chromosphere, transition region, corona, and solar wind. The model calculates the particle density, flow velocity, parallel and perpendicular temperature, and heat flux for all particle species ...
Knowledge about the mass composition is essential for the study of processes and instabilities in the near-Earth magnetotail and plasma sheet. The composition of a plasma determines the mass density, and plays an important role for fundamental plasma properties such as the Alfven speed and plasma pressure. Since ...
Hemorrhage induced by snake venom metalloproteinases (SVMPs) is a complex phenomenon resulting in capillary disruption and blood extravasation. The mechanism of action of SVMPs has been investigated using various methodologies however the precise molecular events associated with microvessel disruption remains not fully understood. To gain insight into the hemorrhagic process we analyzed the global ...
The diffusion rate of baryons through the big-bang plasma is calculated. Fluctuations in baryon density in the early Universe lead to inhomogeneities in the neutron-proton ratio, due to the differential diffusion of these particles through the radiation plasma. For certain types of nonlinear fluctuations, some nucleosynthesis would occur in very ...
An aluminium recombining X-ray laser plasma was probed by keV radiation emitted by an auxiliary plasma source to yield absorption structures on K{alpha} transitions. From this technique we obtain the spatial distribution of the relative abundances of He- to B-like ions at different times during plasma cooling. ...
A microwave torch is designed to produce fan-shaped plasma, which extends about 140 mm laterally. This torch produces an abundance of reactive atomic oxygen in the plasma effluent as evidenced by its emission spectroscopy. The results of the spectral intensity measurements show that the produced atomic oxygen outside the microwave ...
We present in situ measurements in a space plasma showing that thin current sheets the size of an ion inertial length exist and are abundant in strong and intermittent plasma turbulence. Many of these current sheets exhibit the microphysical signatures of reconnection. The spatial scale where intermittency occurs corresponds to the ...
Possibilities of observing abundances of phi mesons and narrow hadronic pairs, as results of QGP and
The 2-to-1 spectra of several astrophysically abundant He-like ions are being studied using the Electron Beam Ion Trap (EBIT) at Lawrence Livermore National Laboratory. Spectra are recorded for a broad range of plasma parameters, including electron densit...
The works on ionization equilibrium available in the literature are briefly reviewed. Fractional ion abundance of coronal ions of C, N, O, Ne, Mg, Al, Si, S, Ca and Fe are calculated by using a new formula for the rate coefficient of dielectric recombinat...
The radiative cooling coefficient has been calculated for a low-density, optically thin gas of cosmic abundances in the range 10/sup 4/-10/sup 8/ K incorporating significant elements through nickel and many recently improved rate calculations. (AIP)
This document describes the processing of nickel samples previously enriched in nickel-62 to form beta emitting thin layer specimens with an isotopic abundance in excess of 10% nickel-63. The operations performed to produce nickel-63 served as a demonstra...
... different fruit abundance. The more frugivorous Hermit Thrushes (Catharus guttatus) had the highest plasma triglyceride, and uric acid ... la abundancia de frutos. La especie más frugívora, Catharus gutta...
NBII National Biological Information Infrastructure
... 13]. Cell volume regulation is accomplished through ion homeostasis across the plasma membrane. Potassium, the most abundant ... volume regulation [14�17], and alterations in potassium homeostasis are ass...
The recombination in a steady-state, plasmoidlike radio-frequency helium plasma is investigated spectroscopically. In an ionization-recombination balance only the radiative-collisional recombination rate involving the abundant atomic ions is of importance...
An experimental program designed to determine the feasibility of employing the abundant rf energy presently available to further heat the ions of the tokamak plasma was performed on the ST Tokamak. Two essential features were explored: 1) wave generation ...
Recent measurements of the cosmic background radiation (CBR) show an enhanced flux in the submillimeter regime, compared to the spectrum of a 2.7 K blackbody. Thermal Comptonization of the relic radiation by a hot nonrelativistic plasma has long been know...
Efforts to discover protein biomarkers in plasma are hampered by the high abundance of few proteins, which interfere with the detection of low-abundant proteins. Different commercially available protein-partitioning products were tested for their ability to lower the detection limit of proteins in 2-D gels. Immuno-depletion using ...
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH). J. Biol. Chem.
Cancer.gov
Increased immunoglobulin G (IgG) and intrathecally produced oligoclonal bands (OGBs) are characteristic of a limited number of inflammatory central nervous system (CNS) diseases and are often directed against the cause of disease. In subacute sclerosing panencephalitis (SSPE), the cause of disease and the target of the oligoclonal response is measles virus (MV). The authors previously showed that ...
Aims: Chemical abundances in solar-type stars are still a much debated topic in many respects. In particular, planet-hosting stars are known to be metal-rich, but whether or not this peculiarity applies also to the chemical composition of the outer stellar atmospheres is still to be clarified. More in general, coronal and photospheric abundances in ...
Spectrohotometric observations at high signal-to-noise ratio for a sample of 62 planetary nebulae are presented, together with the plasma and abundance analyses. The objects were selected homogeneously from the `Strasbourg-ESO Catalogue of Galactic Planetary Nebulae' by their height above the disk (over 300pc) and their H? surface brightness (between 10-12 ...
The abundance measurement in the hot plasma in clusters of galaxies and in poor groups of galaxies with ASCA are summarized. Clusters show narrow concentration of the iron abundance around 0.35 solar for different temperatures of the intracluster medium for 2-7 keV. The analysis including the effect of the XRT show good isothermality ...
leader in providing the scientific basis for new,clean and abundant energy sources. Fusion energy of Science's Fusion Energy Sciences Program leads the nation's effort in the study of plasma,the fourth state ENERGY SCIENCES PROGRAM Progress in fusion energy production Fusion is the power source of the sun
of the basal reticular meshwork formed from the folded plasma membrane. (D) Vacuole aggregation present cytoplasm contains abundant vacuoles of different kinds, different types of granules, dictyosomes, lysosomes with granules and aggregations of vacuoles (Fig. 2E). We found abundant electron-lucent vacuoles clustered
We carried out a detailed study of the Si, Fe and Ni abundances in the cool cores of a representative sample of 26 local galaxy clusters using XMM-Newton data. We have evaluated the systematic errors that are related to the instruments, the plasma codes and the spectral modeling and computed the relative contribution of type Ia and core-collapsed ...
The changes in primordial nucleosynthesis resulting from small corrections to rates for weak processes that connect neutrons and protons are discussed. The weak rates are corrected by improved treatment of Coulomb and radiative corrections, and by inclusion of plasma effects. The calculations lead to a systematic decrease in the predicted /sup 4/He ...
Spectroscopic observations, plasma diagnostics and chemical composition of 15 non-type I planetary nebulae (PNe) in the Large Magellanic Cloud (LMC) are reported. Abundances of He, O, N, S, and Ar are determined and compared with recently obtained data for nebulae both in the Magellanic Clouds and in the Galaxy.
There is a need for objective biomarkers of dietary intake, because self-reporting is often subject to bias. We tested the validity of a biomarker for the fraction of dietary carbohydrate (CHO) from cane sugar and high fructose corn syrup (C(4) sugars) using natural (13)C abundance of plasma glucose. In a randomized, single-blinded, crossover design, 5 ...
A microwave plasma torch system is attached to a low-pressure chamber in this study. The electric field induced in a quartz discharge tube by microwave radiation breaks down the gas at a sufficiently low pressure, igniting the plasma, which is continuously sustained by the microwave radiation. The plasma profile at a very low pressure ...
The proteomic analysis of plasma samples represents a challenge as a result of the presence of highly abundant proteins such as albumin. To enable the detection of biomarkers, which are commonly low-abundance proteins, in complex blood fluids, it is necessary to remove high-abundance proteins efficiently. Moreover, ...
This report describes a new method for desorption of low-molecular weight (LMW) peptides from abundant blood proteins for use in subsequent mass spectrometry analyses. Heating of diluted blood serum to 98�C for 15min resulted in dissociation of LMW peptides from the most abundant blood proteins. Application of blood plasma/serum ...
BackgroundHigh abundance protein depletion is a major challenge in the study of serum/plasma proteomics. Prior to this study, most commercially available kits for depletion of highly abundant proteins had only been tested and evaluated in adult serum/plasma, while the depletion efficiency on umbilical cord ...
Spectra from foil-excited heavy ion beams can be used to investigate the relative abundance and charge state composition of heavy metal contaminants which cause severe radiative energy losses in tokamak-produced plasmas. The degree of ionization of these ...
with water ion prod- ucts. Lower mass ions like H+ become more abundant outward from Saturn and mi stayedThe inner magnetosphere of Saturn: Cassini RPWS cold plasma results from the first encounter J 2005. [1] We present new results from the inner magnetosphere of Saturn obtained by the Radio
We suggest that the variation of the ratio & and n?/n? with baryon density (or rapidity) and/or with temperature should be studied in ultrarelativistic heavy-ion collisions and a change in the variation of these production ratios can be utilized to separate the quark-gluon-plasma contributions from the hadronic background.
Abundant new exact solutions of the Schamel-Korteweg-de Vries (S-KdV) equation and modified Zakharov-Kuznetsov equation arising in plasma and dust plasma are presented by using the extended mapping method and the availability of symbolic computation. These solutions include the Jacobi elliptic function solutions, hyperbolic function ...
lithium, which is abundant in the Earth's crust. As a result, fusion power plants could be located in any fuels are heated above 100,000 degrees Centigrade in a fusion reactor to create a plasma, which, and the heat from the plasma can be used to generate steam. In a fusion power plant, the fuels would need
ABSTRACT: BACKGROUND: microRNAs (miRNA) are short, endogenous transcripts that negatively regulate the expression of specific mRNA targets. miRNAs are found both in tissues and body fluids such as plasma. A major perspective for the use of miRNAs in the clinical setting is as diagnostic plasma markers for neoplasia. While miRNAs are ...
Optical emission spectra from high purity, normal isotope abundance uranium were generated with a glovebox-enclosed inductively coupled plasma (ICP) source. Spectra covering the 1970-7008 Angstrom wavelength range are presented along with general commentary on ICP-U spectroscopy. 18 refs.
We report on a mouse specific SuperMix immunoaffinity separation system for separating low abundance proteins from high and moderate abundance proteins in mouse plasma. When applied in tandem with a mouse IgY7 column that removes the seven most abundant proteins in plasma, the SuperMix column ...
The major challenge of follicular fluid proteomic analysis is the presence of high-abundance proteins that originate from plasma. These proteins can prevent the detection of lower abundant ones, produced locally by follicle cells and that may have important roles in follicular activity. In this study, the novel technology called ...
New calculations by Tucker and Koren for X-radiation from a thin hot plasma are applied to observed X-ray spectra of the Cygnus Loop, Vela X, and Puppis A. These calculations cannot satisfactorily describe the spectra of these three old supernova remnants when evaluated at one temperature and for commonly accepted cosmic abundances. However, all ...
Plots of the Emission Measure vs. Temperature are used to look for deviations from the 'standard' coronal abundance values for Oxygen, Neon, and Magnesium. The fluxes of three strong, relatively simple soft X-ray emission lines (O VIII at 18.97 A, Ne IX at 13.45 A, and Mg XI at 9.17 A) from spectra taken of quiescent active regions are analyzed. For four of the active regions ...
We present and discuss an extreme-ultraviolet spectrum of the RS CVn binary CF Tuc obtained with the short-wavelength (5W) spectrometer on board the Extreme-Ultraviolet Explorer (EUVE) satellite. In addition to a continuum, only two spectral lines attributed to Fe XXII and Fe XXIII are detected. We show that the EUVE data can be reconciled with a solar abundance ...
Microscopic laser-induced breakdown spectroscopy (micro-LIBS) is a promising measurement technique for determining the relative elemental abundances of microscopic spots. Currently, the predominant source of measurement accuracy errors for micro-LIBS is shown to be based on a constant plasma temperature assumption. To reduce these measurement errors ...
Since the earliest days of ultra-relativistic heavy ion physics, there has been interest in strange particle production. Originally, an anomalously large strangeness production was believed to be a signature of the Quark Gluon Plasma. Now the flavor composition of the plasma as reflected in the ratios of abundances of strange and ...
The destruction of NO molecules by an Ar plasma jet in a low-pressure (0.2 Torr) reactor is investigated by means of a 3D hydrodynamic model. The density distribution of species created through molecular kinetics triggered by the collision of Ar+ with NO is calculated, showing that in the case of the most abundant species a quasi-homogeneous density ...
A nonthermal low temperature air plasma jet is characterized and applied to study the plasma effects on oral pathogens and biofilms. Experiments were performed on samples of six defined microorganisms' cultures, including those of gram-positive bacteria and fungi, and on a cultivating biofilm sample of Streptococcus mutans UA159. The results show that the ...
Beryllium-7 (^7Be) decays only by electron capture into lithium-7 (^7Li) with a half life of 53 days. As a result, its decay rate varies with its environment. We desire to study the effect of ionization on its decay rate. We will do this by trapping a ^7Be ion plasma in a cylindrical Malmberg-Penning trap and measuring its and ^7Li's concentration as a function of time by ...
Human serum albumin (HSA) and immunoglobulin G (IgG) represent over 75% of all proteins present in human plasma. These two proteins frequently interfere with detection, determination and purification of low abundance proteins that can be potential biomarkers and biomarker candidates for various diseases. Some low abundance ...
Recent investigations continue to emphasize the importance of glycosylation in various diseases including cancer. In this work, we present a step-by-step protocol describing a method for N-linked glycan profiling of plasma glycoproteins by nanoflow liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS). A large experimental space was ...
It has been conjectured that atomic oxygen and ozone can have a great influence on the plasma oxidation of ultrathin aluminum for magnetic tunnel junctions. In order to measure the density of O and ozone, two-photon absorption laser induced fluorescence measurements are performed in the dc glow plasma that is used for the oxidation process. It was found ...
The increase in the radial line integral of the electron density in the National Bureau of Standards theta-pinch plasma due to the ionization of the titanium impurity has been measured with the use of a He-Ne laser heterodyne quadrature interferometer. Titanium is injected as an impurity into the base gas of hydrogen with the use of a coaxial gun discharge between titanium ...
Metallic ions like Mg(+) and Fe(+) can be quite abundant at E region heights during meteor showers. Since their mass is significantly different from the mass of the normal E region ions like NO(+) and O2(+) the E region plasma will behave quite differently in the presence of these ions. As a consequence, the results of the dispersion relation of the ...
In this work, the Saha equation is solved using atomic data provided by means of a new relativistic-screened hydrogenic model based on analytical potentials to calculate the ionization state and ion abundance for LTE iron plasmas. The plasma effects on the atomic structure are taken into account by including the classical continuum ...
We investigate characteristic feature of the atomic radiation from tin plasmas, which allow one to obtain high power EUV emission at ?=13.5nm efficiently. We develop a collisional radiative model of tin ions to calculate steady-state and time dependent ion abundance, level population, and coefficients of radiative transfer of the ...
This segment of a tutorial about plasma--the main state of matter in space--deals with what plasma is and how it is formed. Background information on electric and magnetic fields is also included because plasmas interact with these fields. Enlargeable graphics and an interactive game about the four states of matter complement the ...
The emission of ions from laser-produced carbon plasmas is investigated by a deconvolution of ion collector signals. The deconvolution is based on the use of Kelly and Dreyfus function expressing the time-resolved ion current to recover hidden peaks in an ion collector signal. The parameters of recovered Cq+ (1 <= q <= 6) currents make possible the quantification of ...
We investigate a new version of the flux-tube model based on joint action of two different processes responsible for vacuum creation of the parton plasma: the dynamical Schwinger mechanism and the geometrical mechanism linked to the dynamical Casimir effect. These two mechanisms act at different time scales. The Casimir mechanism provides the abundant ...
Mass spectrometry was utilized to provide evidence of specific chemical reactions occurring in radio frequency glow discharges of cyclic hydrocarbons and mixtures of these hydrocarbons with oxygen. The hydrocarbons examined were cyclohexane, cyclohexene, and benzene. The most abundant ion observed in low power cyclohexane plasmas was C[sub 6]H[sub 11]+, ...
The plasma membrane separates the cell from the external environment and plays an important role in the stress response of the cell. In this study, we compared plasma membrane proteome modifications of yeast cells exposed to mild (0.4 M NaCl) or high (1 M NaCl) salt stress for 10, 30, or 90 min. Plasma membrane-enriched fractions were ...
This dissertation investigates the development of plasma physics as a scientific discipline, concentrating on the American community. Themes include the role of patronage in modifying disciplinary research interests, the interrelation of the specialties that compose a discipline, and disciplinary identity. The study begins by reviewing work on ionized gases accomplished during ...
Examples of one plasma expanding into another and the consequent radiation of wave energy are abundant in both nature and the laboratory. This work is an experimental study of the expansion of a dense laser-produced plasma (initially, nlpp/n0>>1) into a magnetized background plasma (n0=2�1012 cm-3) capable ...
Clusterin (CLU) is an extracellular chaperone that is likely to play an important role in protein folding quality control. This study identified three deposition disease-associated proteins as major plasma clients for clusterin by studying CLU-client complexes formed in response to physiologically relevant stress (shear stress, approximately 36 dynes/cm(2) at 37 degrees C). ...
Clusterin (CLU) is an extracellular chaperone that is likely to play an important role in protein folding quality control. This study identified three deposition disease-associated proteins as major plasma clients for clusterin by studying CLU-client complexes formed in response to physiologically relevant stress (shear stress, ?36 dynes/cm2 at 37 �C). ...
Elemental abundances in the corona are known to vary from their photospheric values, and this variation is related to the first ionization potential (FIP) of that element. However, the determination of absolute abundances is difficult in the corona due to the lack of Hydrogen lines emitted at coronal temperatures. Therefore, we are forced either to use ...
After a 2 week control period at 400 m, cattle were exposed to 5,000 m simulated altitude for 2 weeks, which was followed by a 2-week post-altitude control period. Plasma cortisol values from blood samples taken every 30 min for a total of 24 h indicated that cortisol was secreted episodically and that a circadian rhythm existed. When cortisol values were grouped into 4, 6-h ...
Human serum albumin (HSA) is the most abundant protein in plasma. It is known to transport drugs as well as endogenous ligands, like free fatty acids (FFA). A mass spectrometry based method was applied to analyze the albumin bound lipid ligands. HSA was isolated from a human plasma pool by cold ethanol fractionation and ion exchange ...
Proteome analysis by conventional approaches is biased against hydrophobic membrane proteins, many of which are also of low abundance. We have isolated plasma membrane sheets from bloodstream forms of Trypanosoma brucei by subcellular fractionation, and then applied a battery of complementary protein separation and identification techniques to identify a ...
The purpose of this study was to determine the effects of consuming raisins, increasing steps walked, or a combination of these interventions on lipoprotein metabolism and appetite hormones by assessing plasma apolipoprotein concentrations, cholesterol ester transfer protein activity, low-density lipoprotein (LDL) receptor messenger RNA (mRNA) abundance, ...
Identification of novel diagnostic or therapeutic biomarkers from human blood plasma would benefit significantly from quantitative measurements of the proteome constituents over a range of physiological conditions. We describe here an initial demonstration of proteome-wide quantitative analysis of human plasma. The approach utilizes post-digestion ...
BackgroundBreast cancer is one of the leading causes of women's death worldwide. It is important to discover a reliable biomarker for the detection of breast cancer. Plasma is the most ideal source for cancer biomarker discovery since many cells cross-communicate through the secretion of soluble proteins into blood.MethodsPlasma proteomes obtained from 6 ...
The discovery of energetic (approximately 1 MeV/nuc) H3 and H2 molecules in Jupiter's magnetosphere is reported. The data, obtained with the LECP instrument on Voyager 2, showed these molecules to be present throughout the magnetosphere and as far as 180 Jupiter radii from the planet, in the 'magnetospheric wind' region. Although the relative abundances of H3 and H2 do not ...
We present a two-component gasdynamic model of an interstellar cloud embedded in hot plasma. It is assumed that the cloud consists of atomic hydrogen gas, and that the interstellar plasma is quasi-neutral. Hydrogen atoms and plasma protons interact through a charge exchange process. Magnetic fields and radiative processes are ignored ...
A variety of invertebrates possess plasma lectins with sialic acid recognition capabilities. One of the best studied of these lectins is limulin, which is a member of the pentraxin family of proteins and is found in the plasma of the American horseshoe crab, Limulus polyphemus. We find that limulin is one of several sialic acid-binding lectins of Limulus ...
Differential, functional, and mapping proteomic analyses of complex biological mixtures suffer from a lack of component resolution. Here we describe the application of ion mobility-mass spectrometry (IMSMS) to this problem. With this approach, components that are separated by liquid chromatography are dispersed based on differences in their mobilities through a buffer gas prior to being analyzed ...
ASCA observation results for four O-stars: ? Ori, ? Ori, ? Ori and ? Pup, are reported. Mg and Si emission lines are discovered from these four stars and the spectra of these stars can be roughly reproduced by a single thin-thermal plasma model. To get acceptable fits, however, a more complex model is required. The interstellar absorption is less than 1021H cm-2 for all cases. ...
We present new calculations of ionization equilibrium fractions of 11 abundant elements (C,N,O,Ne,Mg,Si,S,Ar,Ca,Fe,Ni) as functions of temperature. We also tabulate convenient coefficients for fitting the rates of collisional ionization, radiative recombination, and dielectronic recombination. Many of the ionization rates are based on recent experimental measurements of cross ...
Cellulose is the most abundant biopolymer on earth. The great abundance of cellulose places it at the forefront as a primary source of biomass for renewable biofuels. However, the knowledge of how plant cells make cellulose remains very rudimentary. Cellulose microfibrils are synthesized at the plasma membrane by hexameric protein ...
