Genetical metabolomics (metabolite profiling combined with quantitative trait locus [QTL] analysis) is proposed as a new tool to identify loci that control metabolite abundances. This concept was evaluated in a case study with the model tree Populus. By using HPLC, the peak abundances were analyzed ...
Technology Transfer Automated Retrieval System (TEKTRAN)
Transcript abundance data from cRNA hybridizations to Affymetrix microarrays can be used for simultaneous marker development and genome-wide eQTL (expression Quantitative Trait Loci) analysis of crops. We have shown that it is easily possible to use the information from Affymetrix expression arrays ...
The relationships between quantitative and reproductive fitness traits in animals are of general biological importance for the development of population genetic models and our understanding of evolution, and of great direct economical importance in the breeding of farm animals. Two well investigated quantitative ...
PubMed Central
The mRNA transcript abundance in a cell or tissue is a heritable and quantitative trait that corresponds to the status of gene expression. This principle has been widely applied, using microarrays to identify core regulatory genes for physiological and pathological traits in plants and animals. G...
Mendelian loci that control the expression levels of transcripts are called expression quantitative trait loci (eQTL). When mapping eQTL, we often deal with thousands of expression traits simultaneously, which complicates the statistical model and data analysis. Two simple approaches may be taken in eQTL analysis: (1) individual ...
PubMed
We previously mapped mRNA transcript abundance traits 1 eQTL (expression- quantitative trait loci) using the Barley1 Affymetrix array and "whole plant" tissue from 139 progeny of the Steptoe x Morex (St/Mx) reference barley mapping population. Of the 22,840 probesets (genes) on the array, 15,987 rep...
