The oncogenic potential of high-energy 56Fe particles (1 GeV/nucleon) accelerated with the Alternating Gradient Synchrotron at the Brookhaven National Laboratory was examined utilizing the mouse C3H 10T12 cell model. The dose-averaged LET for high-energy ...

Rats exposed to 0.1-5 Gy of heavy particles ({sup 56}Fe, {sup 40}Ar, {sup 20}Ne or {sup 4}He) showed dose-dependent changes in body temperature. Lower doses of all particles produced hyperthermia, and higher doses of {sup 20}Ne and {sup 56}Fe produced hypothermia. Of the ...

We measured fluence and fragmentation of high-energy (1 or 5 A GeV) 56Fe ions accelerated at the Alternating Gradient Synchrotron or at the NASA Space Radiation Laboratory (Brookhaven National Laboratory, NY, USA) using solid-state CR-39 nuclear track detectors. Different targets (polyethylene, PMMA, C, Al, Pb) were used to produce a ...

We measured fluence and fragmentation of high-energy (1 or 5 A GeV) 56Fe ions accelerated at the Alternating Gradient Synchrotron or at the NASA Space Radiation Laboratory (Brookhaven National Laboratory, NY, USA) using solid-state CR-39 nuclear track detectors. Different targets (polyethylene, PMMA, C, Al, Pb) were used to produce a ...

This report contains papers on the following topics: charge distributions in sup 56 Fe-induced reactions at 14.6 MeV/nucleon; quasi-elastic structure in the reaction sup 56 Fe + sup 56 Fe at 14.6 MeV/nucleon; and effects of particle evaporation in the ...

This report contains papers on the following topics: charge distributions in /sup 56/Fe-induced reactions at 14.6 MeV/nucleon; quasi-elastic structure in the reaction /sup 56/Fe + /sup 56/Fe at 14.6 MeV/nucleon; and effects of particle evaporation in ...

... Induced by 56Fe Heavy-Particle Irradiation: Further ... been exposed to energetic particles (56Fe, 600 ... This loss of mAChR sensitivity was postulated ...

... ions (29), 2.4 for 110 keV/μm argon ions (30), 2.5�3.0 for 145�162 keV/μm carbon ions and 150�l55 keV/μm neon ions (31), 3.31 for 105.8 keV/μm α particles (32), 3.19 for 131 keV/μm neon ions ( ... ...

We examined cell killing and chromatid damage in primary human bronchial epithelial cells irradiated

We measured the fluence of 1 A GeV 56Fe ions accelerated at the National Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory using plastic CR-39 nuclear track detectors. Different targets (polyethylene, PMMA, C, Al, Pb,) were used to produce a large spectrum of charged fragments. CR-39 plastics were exposed both in ...

Alpha-particle emission in neutron reactions with (sup 56)Fe has been studied from threshold to over 30 MeV using the spallation neutron source at WNR/LAMPF. Alpha-particle production cross sections, spectra, and angular distributions were measured at sca...

The neutron capture cross section of exp 56 Fe and exp 58 Fe has been measured in the energy range from 10 to 250 keV relative to the gold standard. A pulsed 3 MV Van de Graaff accelerator and the exp 7 Li(p, n) reaction served as a neutron source. Captur...

... added either during or after irradiation in either cell line. MATERIALS AND METHODS Cells LY cells were derived from a thymic tumor ... ...

Mar 1, 2011 ... Complex Chromosomal Rearrangements Induced in Vivo by Heavy Ions ... human peripheral blood lymphocytes after in vitro exposure to gamma rays or accelerated (56)Fe ions (1 ..... Thesis (15) [x]. show hide NASA Center ...

HZE particles from space radiation raise an important protection concern during long-term astronauts travels Although these particles are less abundant than protons they are more effective in damaging biological systems It is thought that this is due to the frequent production of spatially correlated DNA damaged sites particularly double strand breaks DSB ...

Liulin, a dosimetry-radiometry system, was developed to satisfy the requirements for active flux and dose rate measurements for the flight of the second Bulgarian cosmonaut in 1988. The system consists of a compact battery-operated silicon solid state detector unit and a read/write microcomputer and telemetry unit. We describe the pre-flight calibrations with charged ...

Abstract An unavoidable complication of space travel is exposure to high-charge, high-energy (HZE) particles. In animal studies, exposure of the CNS to HZE-particle radiation leads to neurological alterations similar to those seen in aging or Alzheimer's disease. In this study we examined whether HZE-particle radiation ...

... modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice. Toxicol. Sci 99:628� ... ...

... AGS) (56Fe, Z = 26, 1087 MeV/nucleon at extraction; 1055 MeV/nucleon at the target, ... beam uniformity was ±10%. Sham-irradiated controls were included. ... ...

Lenses of mice irradiated with 250 MeV protons, 670 MeV/amu 20Ne, 600 MeV/amu 56Fe, 350 MeV/amu 56Fe, 600 MeV/amu 93Nb or 593 MeV/amu 139La ions were evaluated by analysing cytopathological indicators which have been implicated in the cataractogenic process. The LETs ranged from 0.39 to 953 keV/microns and the ...

The neutron capture widths of s-wave resonances in exp 56 Fe (27.7 keV), exp 58 Ni(15.4 keV) and exp 60 Ni (12.5 keV) have been determined using a setup completely different from previous experiments. A pulsed 3-MV Van de Graaff accelerator and a kinemati...

... Accelerator. A New Experiment in the Physics of Elementary Particles,. Corporate ... Subject Categories : PARTICLE ACCELERATORS. ...

... Descriptors : *Linear accelerators, *Particle accelerators, Pulse generators, Charged particles, Inductance, Capacitance, Translations, USSR. ...

... Descriptors : *PARTICLE ACCELERATORS, CYCLOTRONS, IONS, LINEAR ACCELERATORS, MAGNETIC PROPERTIES, MATRICES ...

... PARTICLE ACCELERATORS, *TRITIUM, *PRODUCTION ENGINEERING, FEASIBILITY STUDIES, PARTICLE ACCELERATOR TARGETS, HELIUM ...

The nuclear emulsion method was used to study the charge, energy, momentum, and angular characteristics of secondary particles from inelastic interactions of /sup 56/Fe nuclei at energies of 1.8 GeV/nucleon with nuclei of Ag and Br. A systematic comparison of the data with calculations was conducted, using the Dubna version of the ...

... Descriptors : *Linear accelerators, *Ion accelerators, *Particle accelerator components, *Electron accelerators, *Proton accelerators, Electron beams ...

Spallation reactions are important due to their applications in various fields such as astrophysics, neutron sources, accelerator driven systems, and production of radioactive beams. To improve our understanding of the spallation mechanism a complete experiment, called SPALADIN, has been proposed, which aims at measuring as exclusively as possible the final states of the ...

The {sup 65}Cu(n,2n){sup 64}Cu and {sup 64}Zn(n,p){sup 64}Cu cross sections are measured relative to the {sup 56}Fe(n,p){sup 56}Mn cross section by the activation method. The {sup 56}Fe(n,p){sup 56}Mn cross section is then measured relative to an absolutely calibrated neutron flux monitor. Neutrons are produced by ...

... ACCELERATORS, ABSTRACTS, ELECTROSTATIC ACCELERATORS, LINEAR ACCELERATORS, BEVATRONS, SYNCHROCYCLOTRONS ...

... Descriptors : *LINEAR ACCELERATORS, *PROTON ACCELERATORS, *COLLIDER ACCELERATORS, SYMPOSIA, VACUUM CHAMBERS ...

... The identification of alpha particles with the aid of ... Descriptors : (*PARTICLE ACCELERATORS, OPERATION), (*PROTON ACCELERATORS ...

On exploratory class missions, astronauts will be exposed to a variety of heavy particles which differ in terms of quality and energy. Previous research has shown that exposure to 56Fe particles (1 GeV/n) can disrupt performance on taste aversion (CTA) learning and on operant responding using an ascending fixed-ratio schedule of reinforcement. How exposure ...

Neutron and ..cap alpha..-particle emission from the /sup 165/Ho + /sup 56/Fe reaction at 8.5 MeV/A was studied for damped and fusion--fission events. It is shown, that the measured multiplicities, energy spectra and angular distributions of neutrons are consistent with a full equilibration of the excitation energy and the N/Z degree ...

Nuclear level densities and radiative strength functions (RSF) in {sup 56}Fe and {sup 57}Fe were measured using the {sup 57}Fe({sup 3}He,{alpha}{gamma}) and {sup 57}Fe({sup 3}He, {sup 3}He{prime}{gamma}) reactions, respectively, at Oslo Cyclotron Laboratory. A low-energy enhancement in the RSF below 4 MeV energy was observed. This finding cannot be ...

On exploratory class missions astronauts will be exposed to a variety of heavy particles (HZE particles) which differ in terms of particle energy and particle linear energy transfer. The present experiments were designed to evaluate how these physical characteristics of different particles ...

A phenomenological account of particle acceleration is provided along with a detailed summary of the current status of theoretical studies of particle acceleration. Problems are presented which remain when specific mechanisms and observations are confronted. The following specific topics are addressed: solar ...

Research from several sources indicates that young (3 mo) rats exposed to heavy particle irradiation (56Fe irradiation) produces changes in motor behavior as well as alterations in neuronal transmission similar to those seen in aged (22-24 mo) rats. These changes are specific to neuronal systems that are affected by aging. Since ...

... joint planning, national and international politics ... Beam Dynamics; Accelerator Technology I ... Descriptors : *PARTICLE ACCELERATORS, SYMPOSIA ...

... FREE ELECTRON LASERS, PARTICLE BEAMS, LEPTONS, PARTICLE ACCELERATORS, LINEAR ACCELERATORS, CYCLOTRON MAGNETS. ...