Purpose: Reirradiation (re-RT) with concurrent chemotherapy offers a therapeutic option in patients who have locoregional recurrence of head and neck cancer (HNC). The hypoxic cell sensitizer, tirapazamine (TPZ), has demonstrated promising results in first-line therapy for HNC. This phase I trial was designed to test the feasibility of giving TPZ in the re-RT setting. Methods ...

Before the era of breast-conserving therapy, brachytherapy implants were used to treat large inoperable breast tumors. In later years, interstitial brachytherapy with rigid needles or multiple flexible catheters has been used to deliver an additional (boost) dose to the tumor bed after breast-conserving surgery and whole-breast irradiation. Reexcision followed by ...

Purpose: Reirradiation (re-RT) of recurrent head and neck cancer (HNC) may achieve long-term disease control in some patients, at the expense of high rates of late sequelae. Limiting the re-RT targets to the recurrent gross tumor volume (rGTV) would reduce the volumes of reirradiated tissues; however, its effect on tumor recurrence pattern is unknown. ...

May 14, 2007 ... The findings suggest that the flow of air parcels between the eye and ... accelerating the movement of energy that boosts hurricane strength, ...

The Low-Acceleration Research Facility (LARF), an unmanned free-flier that is boosted from low-earth

Laser driven plasma accelerators promise much shorter particle accelerators but their development requires detailed simulations that challenge or exceed current capabilities. We report the first direct simulations of stages up to 1 TeV from simulations using a Lorentz boosted calculation frame resulting in a million times speedup, ...

Purpose: Myeloablative regimens were frequently used for medulloblastoma relapsing after craniospinal irradiation (CSI): in 1997-2002, we used repeated surgery, standard-dose and myeloablative chemotherapy, and reirradiation. Methods and Materials: In 10 patients, reinduction included sequential high-dose etoposide, high-dose cyclophosphamide/vincristine, and high-dose ...

Purpose: To retrospectively determine rates of toxicity, freedom from local progression, and survival in rectal cancer patients treated with reirradiation. Methods and Materials: Between February 2001 and February 2005, 50 patients with a history of pelvic radiotherapy were treated with hyperfractionated accelerated radiotherapy for primary (n = 2 ...

It has been shown [1] that it may be computationally advantageous to perform computer simulations in a boosted frame for a certain class of systems: particle beams interacting with electron clouds, free electron lasers, and laser-plasma accelerators. However, even if the computer model relies on a covariant set of equations, it was also pointed out that ...

Head and neck cancer is typically managed with surgery, radiation therapy, chemotherapy or various combinations of the above. In patients who develop recurrence after radiation therapy, treatment options are limited. Reirradiation can be offered but the amount of additional radiation that can be given is limited and there is an increased risk of serious complications. ...

to structure, metabolism, and mitosis. 6 ~ 4 6 , 58, 72, 78. While these ...... boost acceleration of the Aerobee on a large radius centrifuge with- ...

The concept to use twin turbo-powered boosters for acceleration to supersonic staging speed followed

Osteoradionecrosis (ORN) is one of the common late adverse effects that follow radiation therapy for head and neck cancers. ORN usually develops on the mandible and less frequently on the maxilla. We present three cases of ORN of the cervical vertebrae, which is rarely reported. Two patients suffered from secondary osteomyelitis after neoadjuvant chemotherapy followed by definitive concurrent ...

The effects of hyperbolic rotation in Minkowski space resulting from the use of Lorentz boosted frames of calculation on laser propagation in plasmas are analyzed. Selection of a boost frame at the laser group velocity is shown to alter the laser spectrum, allowing the use of higher boost velocities. The technique is applied to ...

A superconducting heavy-ion accelerator is being installed to boost the energies of beams from the ANU 14UD pelletron. The design of the beam transport system and the calculated beam characteristics are described. Features include a waist-to-waist transve...

Objectives: To evaluate the efficacy and treatment-related toxicity of accelerated hyperfractionation field-involved re-irradiation combined with concurrent capecitabine chemotherapy for locally recurrent and irresectable rectal cancer (LRIRC). Methods: 72 patients with LRIRC who underwent the treatment were studied. Three-dimensional conformal ...

We examine the re-acceleration of a bunched beam through a linear induction accelerator (LIA) cavity, with attention to the energy lost through coupling to the TM modes of the structure. We find that the energy lost at 1 kA peak current is a small fraction of the boost which the LIA is designed to impart. We discuss implications for a ...

The use of an exhaust-driven boosting device can significantly improve the performance of a vehicle using a small displacement engine. One of the concerns relative to the performance of vehicles using these devices is ''turbo lag,'' or the period of time during which no boost is generated. This paper presents the results ...

Theories and mechanisms for accelerating macroparticles, which weigh a fraction of a gram, to several hundred km/sec are described. Macrons can be charged for acceleration in an electrostatic field, although the method is limited by the amount of charge the macron can carry without being torn apart, by chances of the presence of residual gas in a linear ...

A carburetor for an internal combustion engine includes a power boost device for boosting engine output during acceleration or at high speeds which adjusts its air-fuel ratio and/or boost timing according to the alcohol content of the fuel. The power device includes a nitrile rubber swelling member which swells in ...

in the hydrodynamic stage. Relaxing the ideal fluid assumption amounts to the introduction of viscous effects-boost-invariant expanding fluid with viscosity. The cooling rate and the acceleration of the longitudinal flow are reduced density profile and the Bjorken collective lon- gitudinal flow of the fluid. 3. RHIC results Eqs. (2

We solve the problem of the relativistic rocket by making use of the relation between Lorentzian and Galilean velocities, as well as the laws of superposition of successive collinear Lorentz boosts in the limit of infinitesimal boosts. The solution is conceptually simple, and technically straightforward, and provides an example of a powerful method that ...

Stimulus funds boost musculoskeletal research By Annie Hayashi More than $10 billion in ARRA money. Virdi, PhD The National Institutes of Health (NIH) received more than $10.4 billion in ARRA funds to accelerate biomedical research. Of that amount, $8.2 billion has been allocated for "extramural scientific

Apr 1, 2010 ... STICS does not apply a post-acceleration voltage to boost ion energy, so low mass ions do not have enough kinetic energy at the lower E/Q ...

Relativity - One Gravity Acceleration trips 1 g x 1 year = 1.0 Lorentz Boost Warp (from Star Trek) Galactic). 2) Star Trek had something correct ! Warp

Space Based Interceptors (SBIs) are small, smart rockets in space that can intercept missiles in boost before they can deploy countermeasures. This note discusses their scaling and that of their constellations with delays, peak velocites, and acceleration...

Ramjet propulsion using solid propellant for post-boost acceleration of missiles exhibits several favorable properties, brought about by heterogeneous combustion. A simplified theory for calculating the performance of possible propellants is presented; th...

Ramjet propulsion using solid propellant for post-boost acceleration of missiles exhibits several favorable properties, brought about by heterogeneous combustion. A simplified theory for calculating the performance of possible propellants classified with ...

Ramjet propulsion using solid propellant for post-boost acceleration of missiles exhibits several favorable properties, brought about by heterogeneous combustion. A simplified theory for calculating the performance of possible propellants is presented, an...

There are three distinct requirements for Military Energy Storage: * Starting, Lighting and Ignition - Batteries provide electric power to start the vehicle power generation (Engines / APUs); * Hybrid Vehicle Boost Acceleration and Regenerative Braking En...

The design, development, and testing of two hightemperature transducers are described. One measures vibration amplitude and frequency, and the other measures acceleration. Both were designed to detect aerodynamic panel flutter during boost and re-entry of...

Cancer of the Pharynx; Cancer of the Larynx; Cancer of the Neck; Paranasal Sinus Neoplasms; Cancer of the Head

It can be computationally advantageous to perform computer simulations in a Lorentz boosted frame for a certain class of systems. However, even if the computer model relies on a covariant set of equations, it has been pointed out that algorithmic difficulties related to discretization errors may have to be overcome in order to take full advantage of the potential speedup. We ...

S>Separation of effects of thermal annealing and radiation enhancement of defect annealing in the reirradiation of AGOT graphite at 350 deg C after neutron irradiation at 30 deg C is accomplished. The reirradiations are seen to involve competitive reactions between production and decomposition of interstitial complexes. (R.E.U.)

The boosting of electrons from a Maxwellian distribution into a suprathermal power-law tail has long been recognized as an important bottleneck governing the subsequent acceleration of some of these electrons to relativistic energies. This is the seed or injection problem. The author studied this boosting process using a test-particle ...

The rebatron is a high-current compact accelerator concept which differs from the modified betatron and the stellatron. In the latter devices, the acceleration mechanism is the relatively slow betatron mechanism. In the rebatron, there is rapid acceleration of the electrons as the beam repeatedly passes through a small (few centimeters ...

It can be computationally advantageous to perform computer simulations in a Lorentz boosted frame for a certain class of particle acceleration devices or problems such as: free electron laser, laser-plasma accelerator, particle beams interacting with electron clouds [1]. Complications arising from calculating in a Lorentz ...

Electron-spin resonance (ESR) has been used to investigate defect formation, anneal, and migration effects in commercially available high-quality synthetic quartz. Electronic-Grade and premium Q material, both unswept and swept, were included in the study and an electron accelerator was used for all irradiations. Previously unreported holelike and electronlike paramagnetic ...

Purpose: Institutional and cooperative group experience has demonstrated the feasibility of reirradiation for head and neck cancer. Limited data are available regarding the use of intensity-modulated radiotherapy (IMRT) for this indication. We reviewed our initial experience using IMRT for previously irradiated head and neck cancer patients. Methods and Materials: Records of ...

PURPOSE: Local recurrence rates are high in patients with locally advanced NSCLC treated with 60 to 66Gy in 2Gy fractions. It is hypothesised that boosting volumes with high SUV on the pre-treatment FDG-PET scan potentially increases local control while maintaining acceptable toxicity levels. We compared two approaches: threshold-based dose painting by contours (DPBC) with ...

Brachytherapy techniques by permanent implant of radioactive sources or by temporary high-dose-rate (HDR) fractions are nowadays extensively used for the treatment of prostatic carcinoma. Long-term results (at 20 years) concerning large amount of patients have been published by major centers confirming both in terms of efficacy and toxicities that permanent implant of radioactive iodine-125 seeds ...

For an energy-efficient accelerator system to be used for a free-electron laser, the stability of an energy-recovery system utilizing a bridge coupler placed between the accelerator and the decelerator is studied numerically. Energy is recovered by recirculating the accelerated electron beam through the decelerator; the recovered ...

Fifty-one cats and dogs with tumor recurrence after irradiation were treated with a second course of radiotherapy, using either teletherapy or brachytherapy. Eighty-six percent of the tumors had partial or complete response at 2 months after reirradiation. Tumor response was significantly (P = 0.041) affected when the interval between the 2 courses of irradiation was greater ...

Pyroelectric crystal x-ray generators [1] were first reported in 1992. These crystals have a nonzero spontaneous polarization at all temperatures below their Curie temperature. A change in crystal temperature will result in a strong electric field at its surface. If the Z- face on a Z-cut pyroelectric crystal is located in a gas at mTorr pressure the energy of electrons that are ...

The quantitative analysis of the cell dose-survival curves, the randomness of cell killing by radiation, the probabilistic basis of the response to irradiation of tumors and normal tissues, the understanding of the biological mechanisms underlying to this response, the rationale for dose-time and fractionation in radiotherapy, the introduction of the concepts of tumor control probability (TCP) and ...