PURPOSE: : To report outcome and toxicity of concurrent radiochemotherapy with carboplatin and paclitaxel in advanced squamous cell carcinomas of the oropharynx and hypopharynx. PATIENTS AND METHODS: : Advanced inoperable carcinomas of the ...

... Descriptors : *LINEAR ACCELERATORS, *MEDICAL EQUIPMENT, ELECTRON ACCELERATORS, RADIOTHERAPY, ELECTRON BEAMS ...

The physical, mechanical and dosimetric features of betatrons are described and discussed. Reference is also made to difficulties that may arise and the limitations associated with their employment as electron accelerators in radiotherapy. PMID:828281

Although the term "targeted therapy" is used to described new molecular approaches derived from the recent increase in the knowledge of cancer biology, radiation therapy is a "targeted therapy" used against cancer. Dose fractionation changes and time treatment duration modifications are used to specifically increase the anti tumor effects of ionising radiation while minimising normal tissue impact ...

This paper outlines technological considerations in the design of accelerator facilities for medical applications. Emphasis is placed on the specific requirements for MARIA, a radioisotope and radiotherapy facility being planned in Edmonton, Canada. The m...

Continuous, hyperfractionated, accelerated radiotherapy (CHART) was devised to give the maximum chance of improving clinical radiotherapy and was based upon available radiobiological evidence. A pilot study, begun in 1985, has now included 210 patients. When comparison is made with previously treated cases, improved results have been ...

Continuous, hyperfractionated, accelerated radiotherapy (CHART) has given high levels of tumour control in advanced head and neck and bronchial carcinomas. In general, late changes have appeared less than after conventional radiotherapy but despite a prediction of reduced risk of spinal cord damage, two cases of radiation myelitis have ...