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1
Accelerated partial breast irradiation: technically feasible but who will benefit?
2005-04-05

Modern breast cancer radiotherapy aims to increase uncomplicated cure rates. A priority is reduction of late effects which include chronic chest wall or breast pain, poor cosmesis, and cardiac toxicity. As breast screening detects early cancers we may be able to safely restrict irradiation postlumpectomy to the tumour bed with a margin, defining a 'partial breast' target volume for treatment. ...

PubMed Central

2
Models and Analogues for the Evaluation of Human ...
1979-06-01

... MODELS, NATO, VIBRATION, BRAIN, THREE DIMENSIONAL ... PHYSIOLOGY), IMPACT ACCELERATION, NECK(ANATOMY), CRASH INJURIES. ...

DTIC Science & Technology

3
Effects of Waves on the Boundary Layer of a Surface-Piercing ...
1987-09-01

... THREE DIMENSIONAL FLOW, ACCELERATION, BOUNDARIES, BOUNDARY LAYER ... DOWNSTREAM FLOW, FLAT PLATE MODELS, FLOW ...

DTIC Science & Technology

4
Acceleration d'Electrons dans Une Onde Plasma Electronique Relativiste (Electron Acceleration in a Relativistic Electron Plasma Wave).
1990-01-01

The development of a three dimensional code calculating the electron beam trajectory in accelerating structure is reported. An electron plasma wave excited to a known amplitude is supposed and the electron acceleration in the field of this wave is analyti...

National Technical Information Service (NTIS)

5
Three-Dimensional Particle Simulations of Ion Optics Plasma ... - NASA

density, electron temperature, and plasma potential), and the screen grid and accelerator grid voltage. In addition, other factors, such primary electrons ...

NASA Website

6
High Strain Lagrangian Hydrodynamics: A Three Dimensional ...
1993-03-01

... FG and H represent the total acceleration of, work per unit mass and ... where the density is plotted as a function of radius for each particle at time = 48 ...

DTIC Science & Technology

7
Accelerated Three-Dimensional Upper Airway MRI Using Compressed Sensing

Accelerated Three-Dimensional Upper Airway MRI Using Compressed Sensing Yoon-Chul Kim,* Shrikanth S). Compressed sensing MRI (CS-MRI) relies only on sparsity of the final reconstructed image in a transform speech production. CONCLUSIONS We have demonstrated the application of compressed sensing (CS) MRI

E-print Network

8
Acute Toxicity After Hypofractionated Conformal Radiotherapy for Localized Prostate Cancer: Nonrandomized Contemporary Comparison With Standard Fractionation
2008-11-01

Purpose: To prospectively study acute rectal and urinary reactions from three-dimensional conformal external beam radiotherapy for localized prostate cancer comparing two hypofractionation regimens with standard fractionation (standard). The hypofractionation regimens were designed to avoid more late reactions in the ...

Energy Citations Database

9
Modified Betatron Accelerator Studies.
1983-01-01

Results of an extensive study of the modified betatron accelerators are reported. The topics are beam injection, equilibrium and stability. Three-dimensional particle simulations of injections were performed. The results show good agreement with theory. V...

National Technical Information Service (NTIS)

10
Investigation of Linac-Based Image-Guided Hypofractionated Prostate Radiotherapy
2007-07-01

A hypofractionation treatment protocol for prostate cancer was initiated in our department in December 2003. The treatment regimen consists of a total dose of 36.25 Gy delivered at 7.25 Gy per fraction over 10 days. We discuss the rationale for such a prostate hypofractionation protocol and the need for frequent prostate imaging during treatment. The ...

Energy Citations Database

11
Biological dose volume histograms during conformal hypofractionated accelerated radiotherapy for prostate cancer
2007-01-15

Radiobiological data suggest that prostate cancer has a low {alpha}/{beta} ratio. Large radiotherapy fractions may, therefore, prove more efficacious than standard radiotherapy, while radiotherapy acceleration should further improve control rates. This study describes the radiobiology of a conformal hypofractionated accelerated ...

Energy Citations Database

12
How to realize uniform three-dimensional ellipsoidal electron bunches.
2004-08-25

Uniform three-dimensional ellipsoidal distributions of charge are the ultimate goal in charged particle accelerator physics because of their linear internal force fields. Such bunches remain ellipsoidal with perfectly linear position-momentum phase space correlations in any linear transport system. We present a method, based on photoemission by radially ...

PubMed

13
Mathematical Model for Evaluating Incidence of Acute Rectal Toxicity During Conventional or Hypofractionated Radiotherapy Courses for Prostate Cancer
2009-04-01

Purpose: To describe the radiation-induced acute rectal toxicity (ART) using a modified Lyman-Kutcher-Burman normal tissue complication probability model and parameters set, taking into account the overall treatment time. Methods and Materials: A total of 160 patients underwent three-dimensional conformal radiotherapy to the prostate and seminal vesicles and were randomized to ...

Energy Citations Database

14
[Debate about breast cancer: "Cons: Intraoperative radiotherapy"
2011-07-26

Early breast cancer incidence increases owing to mammography screening. Hypofractionated radiotherapy is more and more proposed in women with low local relapse risk breast cancer, especially accelerated partial breast irradiation. Various irradiation modalities have been reported: brachytherapy, intraoperative irradiation, 3D-conformal ...

PubMed

15
New Developments in Proton Therapy Systems
2009-07-25

Proton beams can provide better dose conformity to the treatment target compared to commonly used photon and electron beams allowing for dose escalation and/or hypofractionation to increase local tumor control, reduce normal tissue complications and/or treatment time/cost. This paper reviews three novel proton accelerator designs that aim at cost-effective ...

Energy Citations Database

16
Using Two-Dimensional and Perspective Views of Terrain.
2000-01-01

The use of three dimensional (3-D) perspective views on flat screens for military command and control tasks is accelerating. The question is when and how to use these displays effectively. We report the results of three experiments to test the hypotheses ...

National Technical Information Service (NTIS)

17
Three-Dimensional Analysis of the GMBK (Gigawatt Multiple Beam Klystron).
2001-01-01

The basis of this work is the 3-D simulation analysis and assessment of the GMBK design performed with the Stanford Linear Accelerator Center (SLAC). A 19-beam hexagonal-packed Multiple Beam Klystron was of interest to SLAC. The emphasis of the project, e...

National Technical Information Service (NTIS)

18
Simulation of the Fermilab Booster Using Synergia.
2005-01-01

High precision modeling of space-charge effects is essential for designing future accelerators as well as optimizing the performance of existing machines. Synergia is a high-fidelity parallel beam dynamics simulation package with fully three dimensional s...

National Technical Information Service (NTIS)

19
Rotor Blade Boundary Layer Measurement Hardware Feasibility Demonstration.
1972-01-01

A traverse mechanism which allows the measurement of the three dimensional boundary layers on a helicopter rotor blade has been built and tested on a full scale rotor to full scale conditions producing centrifugal accelerations in excess of 400 g and Mach...

National Technical Information Service (NTIS)

20
QUARTZ: A Numerical Simulation of an Asymmetric Electrostatic Accelerator.
1979-01-01

The physics and numerical aspects of the development of the computer code QUARTZ are given. This code includes the (1) use of a finite element code to obtain solutions of Poisson's equation in an asymmetric, three-dimensional volume; (2) inclusion of spac...

National Technical Information Service (NTIS)

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21
Dynamic Stress Analysis of Axisymmetric Structures under Arbitrary Loading.
1969-01-01

A finite element method is presented for the dynamic analysis of complex axisymmetric structures subjected to any arbitrary static or dynamic loading or base acceleration. The three dimensional axisymmetric continuum is represented either as axisymmetric ...

National Technical Information Service (NTIS)

22
Four and five dimensional radiotherapy with reference to prostate cancer--definitions, state of the art and further directions--an overview.
2011-06-01

Radiotherapy (RT) always requires a compromise between tumor control and normal tissue side-effects. Technical innovation in radiation therapy (RT), such as three dimensional RT, is now established. Concerning prostate cancer (PC), it is reasonable to assume that RT of PC will increase in the future. The combination of small margins, a movable target ...

PubMed

23
Three-Dimensional Photonic Crystal-Laser-Driven Accelerator Structures.
2006-01-01

We discuss simulated photonic crystal structure designs for laser-driven particle acceleration, focusing on three-dimensional planar structures based on the so-called ''woodpile'' lattice. We describe guiding of a speed-of-light accelerating mode by a def...

National Technical Information Service (NTIS)

24
Hypofractionated Accelerated Radiotherapy With Concurrent Chemotherapy For Locally Advanced Squamous Cell Carcinoma of the Head and Neck
2007-04-01

Purpose: To investigate the tumor control rates in locally advanced head-and-neck cancer using accelerated hypofractionated radiotherapy with chemotherapy. Methods and Materials: The data from patients with squamous cell cancer of the larynx, oropharynx, oral cavity, and hypopharynx (International Union Against Cancer Stage II-IV), who received ...

Energy Citations Database

25
Quality Assurance of Immobilization and Target Localization Systems for Frameless Stereotactic Cranial and Extracranial Hypofractionated Radiotherapy
2008-05-01

The success of stereotactic radiosurgery has stimulated significant interest in the application of such an approach for the treatment of extracranial tumors. The potential benefits of reduced healthcare costs and improved patient outcomes that could be realized in a high-precision, hypofractionated treatment paradigm are numerous. Image-guidance technologies are eliminating ...

Energy Citations Database

26
Rapid three-dimensional imaging of defect distributions using a high-intensity positron microbeam
2009-05-11

An intense positron microbeam generated by an electron accelerator has been developed for obtaining three-dimensional positron lifetime mappings in a sample to permit visual evaluation of defect distributions. The beam diameter at the sample was 80-100 {mu}m. The counting rate of the positron annihilation {gamma} rays used to measure positron lifetime was ...

Energy Citations Database

27
Monte Carlo calculation of dose distribution in early stage NSCLC patients planned for accelerated hypofractionated radiation therapy in the NCIC-BR25 protocol
2010-02-01

The dosimetric consequences of plans optimized using a commercial treatment planning system (TPS) for hypofractionated radiation therapy are evaluated by re-calculating with Monte Carlo (MC). Planning guidelines were in strict accordance with the Canadian BR25 protocol which is similar to the RTOG 0236 and 0618 protocols in patient eligibility and total dose, but has a ...

NASA Astrophysics Data System (ADS)

28
Three-dimensional analysis for explosions of a propane-air mixture in cylindrical vessels
1988-07-01

A mathematically simple spatial difference method has been applied for analysing three-dimensionally, and for illustrating graphically, the process of the development of a flame after the propane-air stoichiometric mixture is ignited. The calculated results show that the mathematical simulation can well express the process of mixture explosion in cylindrical vessels, and can ...

NASA Astrophysics Data System (ADS)

29
Automatic three-dimensional dosimetry in electron beams
1974-04-30

From thirteenth international congress of radiology; Madrid, Spain (15 Oct 1973). Automatic three-dimensional dosimetry in electron beams is a method for either reducing any undesired distortion of the isodose curves or for modifying the usual isodose patterns to match any tumor shape. The term automatic'' is used to mean selfregulating or ...

Energy Citations Database

30
A multigrid scheme for three dimensional body-fitted coordinates in turbomachine applications
1983-03-01

An efficient numerical scheme for the generation of curvilinear body-fitted coordinate systems in three dimensions is presented. The grid is obtained by the solution of a system of three elliptic partial differential equations. The method is based on the classical SOR scheme with an acceleration of convergence using the multigrid technique. The full approximation scheme has ...

Energy Citations Database

31
THREE-DIMENSIONAL HOLOGRAPHY.
1966-09-07

... Accession Number : AD0643165. Title : THREE-DIMENSIONAL HOLOGRAPHY. ... Three-dimensional holography is emphasized. ...

DTIC Science & Technology

32
On the Origin and Evolution of Three Dimensional Effects in ...
1979-12-01

Page 1. 0 TON THE ORIGIN AND EVOLUTION OF THREE DIMENSIONAL ... On the Origin and Evolution of Three Dimensional 'inal echnical geport. ...

DTIC Science & Technology

33
Multifocal Three Dimensional Bootlace Lenses
1981-03-12

... MULTIFOCAL THREE DIMENSIONAL BOOTLACE LENSES continuing project. ... MULTIFOCAL THREE DIMENSIONAL BOOTLACE LENSES ...

DTIC Science & Technology

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