Provide acceleration measurement systems that meet the requirements of the researchers on ... SAMS measures the acceleration environment in the 0.01 to ...

Jul 16, 1999 ... Space Acceleration Measurement System (SAMS) Operations ... Space Acceleration Measurement System (SAMS) sensor device. The SAMS ...

data were collected by the Space Acceleration Measurement System (SAMS) ... This report presents an overview of the SAMS acceleration measurements ...

Senescence accelerated mouse (SAM), a murine model of accelerated senescence, was established by Toshio Takeda and colleagues. SAM consists of series of SAMP (prone) and SAMR (resistant) lines. All SAMP lines (from SAMP1 to SAMP11) are characterized by accelerated ...

The decline in olfaction with age is well documented in histological, psychological, and electroencephalographical studies. However, there are few electrophysiological studies on changes in the sensitivity of the peripheral olfactory cells with age. We evaluated the behavior, the amplitude of electro-olfactogram (EOG), and the thickness of the olfactory epithelium in the ...

The Space Acceleration Measurement System II (SAMS-II) measures accelerations ... To complement the SAMS-II measurements, the Microgravity Acceleration ...

RESEARCH ARTICLE Age-related disruptions of circadian rhythm and memory in the senescence and circadian rhythms with a focus on the senescence-accelerated mouse (SAM) as a model of aging. We explore-Fos . circadian rhythms . mouse . running wheel . SAMP8 . suprachiasmatic nucleus Cognitive impairments are well

Feb 8, 2011 ... The MAMS is a complimentary acceleration measurement system to SAMS. While the SAMS system measures acceleration disturbances from ...

Supports PIs by mapping acceleration environment on multiple platforms: ... SAMS - II - The Acceleration Measurement System for mapping ...

Jul 16, 1999 ... Space Acceleration Measurement System (SAMS) sensor device. The SAMS sensor consisted of three sensor heads positioned orthogonally ...

Feb 8, 2011 ... SAMS-II measures vibrations and transient acceleration disturbances resulting from ISS vehicle activities, ISS systems operations, experiment ...

Feb 1, 1994 ... The SAMS unit flew on STS-62 to monitor onboard accelerations that could disrupt shuttle experiments.

Genetic analysis of learning and memory deficits (LMD) in senescence-accelerated mouse P8 (SAMP8) was performed by cross-mating SAMP8 and Japanese Fancy Mouse 1 (JF1). The incidence of LMD in the F2 generation showed a 3:1 segregation ratio of mice with LMD to normal mice, and the incidence of LMD in the backcross generation of the F1 ...

Mar 17, 2003 ... NASA's Glenn Research Center has developed an innovative space acceleration measurement system, the SAMS-FF for free-flyer spacecraft.

The NASA Microgravity Science and Applications Division (MSAD) sponsors the Space Acceleration Measurement System (SAMS) to support microgravity science experiments with microgravity acceleration measurements. In the past, SAMS was flown exclusively on th...

The convergence rate of the Schwarz Alternating Method(SAM) is studied for applications involving the solution of elliptic equations on composite grids. Such problems arise when solvers which can only be used on special domains, such as rectangles, are used for more general region; and in the disection of problems for parallel processing. It is shown that the convergence rate ...

(AMAMS). Key words: MEMS, SAMS, Microgravity, Space Acceleration ... The Advanced Microgravity Acceleration Measurement Systems (AMAMS) project is ...

... nitrogen. The number of tumors in each gland and the number of glands with tumor were recorded for every mouse. Sam ...

PurposeTo investigate senescent evidence in corneal endothelial cells (CECs) of the senescence-accelerated mouse (SAM), which is considered a suitable animal model for the further study of the senescent mechanism�in CECs.MethodsThirty-six male mice from a senescence resistant mouse strain ...

The NASA Microgravity Science and Applications Division (MSAD) sponsors science experiments on a variety of microgravity carriers, including Orbiter missions and Russia's Mir space station. The MSAD sponsors the Space Acceleration Measurement System (SAMS...

Mar 5, 2001 ... The Space Acceleration Measurement System II (SAMS-II) will measure accelerations caused by vehicle, crew and equipment disturbances. ...

The Space Acceleration Measurement System (SAMS) project at the NASA Glenn Research Center (GRC) has

The Department of Energy's Thomas Jefferson National Accelerator Facility. Sam Garcia, Robert Linza, and Daniel Meagher. Jacobs Engineering ...

SCR. Milestones. ISS Resource Requirements. Revision Date: 9/22/2008. Objective: f Provide acceleration measurement systems that meet the ...

Principal Investigator(s): ... Investigators seek to better understand the ... SAMS-II measurements help investigators characterize accelerations that influence ISS ...

Jun 18, 1999 ... To quantify the level of these disturbances, NASA developed the Space Acceleration Measurement System (SAMS) series to collect data ...

Jul 16, 1999 ... Space Acceleration Measurement System (SAMS) Operations ... The objectives of this experiment were: (1) to measure the microgravity ...

Jul 16, 1999 ... Space Acceleration Measurement System (SAMS) electronic box in the Mir Space Station. The electronic box consisted of a control panel and ...

During NASA Increment 4 (January to May 1997), about 5 gigabytes of acceleration data were collected

acceleration environment in the 0.01 to 400 Hz range for payloads. Relevance/ Impact: f. SAMS will measure the acceleration environment for research ...

Apr 6, 2011 ... SAMS-II measures vibrations and transient acceleration disturbances resulting from ISS vehicle activities, ISS systems operations, experiment ...

Sam68 plays an essential role in mouse spermatogenesis and male fertility. Herein, we report an interaction between Sam68 and the phosphorylated forms of the RNA polymerase II (RNAPII) in meiotic spermatocytes. RNase treatment decreased but did not abolish the interaction, consistently with in vitro binding of RNAPII to the ...

Two accelerometers provided acceleration data during the STS-75 mission in support of the third United States Microgravity Payload (USMP-3) experiments. The Orbital Acceleration Research Experiment (OARE) and the Space Acceleration Measurement System (SAM...

Oxygen enhancement ratio and relative biological effectiveness of accelerated helium nuclei on mouse

The STS-66 SAMS data represent the microgravity environment in the 0.01 Hz to 10 Hz range. Variations in the environment related to differing levels of crew ...

The SAMS project at the NASA Lewis Research Center supports microgravity science experiments by measuring microgravity accelerations during on-orbit ...

Jan 11, 2002 ... History of Shuttle-Based Measurements. In the mid-1980's. the NASA Microgravity Research Division directed the Glenn Research Center ...

Mar 3, 2009 ... Magnus initiated a software image upgrade ( ghosting or cloning ) of the SAMS II (Space Acceleration Measurement System II) hard drives ...

The aim of this work was to characterize a mouse model of experimental menopause and cardiovascular aging that closely reflects menopause in women. Senescence accelerated mouse (SAM)-Resistant type 1 (SAMR1, n=30) and SAM-Prone type 8 (SAMP8, n=30) were separated at 5months of age into three ...

The main purpose of this study was to investigate whether consumption of diets enriched in antioxidants attenuates the level of oxidative stress in the senescence-accelerated mouse (SAM). In separate and independent studies, two different dietary mixtures, one enriched with vitamin E, vitamin C, L-carnitine, and lipoic acid (Diet I) ...

The main purpose of this study was to investigate whether consumption of diets enriched in antioxidants attenuates the level of oxidative stress in the senescence-accelerated mouse (SAM). In separate and independent studies, two different dietary mixtures, one enriched with vitamin E, vitamin C, L-carnitine, and lipoic acid (Diet I) ...

This paper illustrates the applicability of neural networks in classifying events using Space Acceleration Measurement System (SAMS) data. Computer programs have been written in the MATLAB environment for the following purposes: automatic retrieval of SAMS data from NASA CDROM disks, computation of power spectral densities for ...

... RADIATION EFFECTS, CANCER, GROWTH(PHYSIOLOGY), HISTOLOGY, LABORATORY ANIMALS, MITOSIS, PATHOLOGY, PRODUCTION ...

Animal models are valuable research tools towards effective prevention of sarcopenia and towards a better understanding of the mechanisms underlying skeletal muscle aging. We investigated whether senescence-accelerated mouse (SAM) strains provide valid models for skeletal muscle aging studies. Male senescence-prone mice SAMP6 and SAMP8 ...

Mitochondrial oxidative damage from free radicals may be a factor underlying aging. We investigated whether long-term administration of physiological levels of melatonin, a direct free radical scavenger and indirect antioxidant, influences mitochondrial respiratory activity in liver of senescence-accelerated mice (SAM). Liver was obtained in the middle of ...

Oct 27, 2003 ... NASA's Glenn Research Center has developed an innovative space acceleration measurement system, the SAMS-FF for free-flyer spacecraft.

The NASA Microgravity Science and Applications Division (MSAD) sponsors science experiments on a variety of microgravity carriers, including sounding rockets, drop towers, parabolic aircraft, and Orbiter missions. The MSAD sponsors the Space Acceleration ...

Carbon 14 terrestial ages were determined with low level minicomputers and accelerator mass spectrometry on 1 Yamato and 18 Allan Hills and nearby sited meteorites. Techniques for an accelerator mass spectrometer which make C(14) measurements on small sam...

Renin secretion, as measured by changes in peripheral venous renin levels, was used to evaluate the part played by the reninangiotensin system in the response to +Gz acceleration. Centrifuge runs were done on the USAF SAM Human Centrifuge and the subjects...

The NASA Microgravity Science and Applications Division (MSAD) sponsors the Space Acceleration Measurement System (SAMS) to support microgravity science experiments with microgravity acceleration measurements. MSAD is currently sponsoring science experime...

The NASA Microgravity Science and Applications Division (MSAD) sponsors the Space Acceleration Measurement System (SAMS) to support microgravity science experiments with microgravity acceleration measurements. In the past, SAMS was flown exclusively on the NASA Orbiters. MSAD is currently sponsoring science ...

The senescence-accelerated mouse (SAM) is a naturally occurring animal model for accelerated aging after normal development and maturation. SAMP1 strain was reported to show age-related structural and functional changes in lung and to be a murine model of senile lung. We postulated that aging of lung is an ...

The misfolding and aggregation of ?-amyloid peptides (A?) into amyloid fibrils, a process that has been pathologically linked to the onset of Alzheimer's disease, is dependent on the presence of a heterogeneous surface (e.g., cell membrane). Understanding of the kinetics of amyloid fibril formation and associated structural transition from monomers to intermediates and eventually to fibrils is ...

Both the identity and source of the rodent collagenase(s) that mediates matrix remodeling in liver fibrosis remain elusive. We have recently demonstrated an unequivocal role for scar-associated macrophages (SAMs) in the spontaneous resolution of liver fibrosis and sought to determine whether SAMs are the source of matrix metalloproteinase (MMP) 13 ...

.00 symmetri o th othe hand bound fo 1,B o sam for with # # # 0.0013 respect el . B relaxin requiremen o

Learn about position, velocity, and acceleration graphs. Move the little man back and forth with the mouse and plot his motion. Set the position, velocity, or acceleration and let the simulation move the man for you.

Senescence-accelerated mouse (SAM) prone/8 (SAMP8) is a good animal model to investigate the fundamental mechanisms of age-related learning and memory deficits such as Alzheimer's disease (AD) at the gene and protein levels, and SAM resistant/1 (SAMR1) is its normal control. Calcium/calmodulin-dependent protein ...

Sik (mouse Src-related intestinal kinase) and its orthologue BRK (human breast tumor kinase) are intracellular tyrosine kinases that are distantly related to the Src family and have a similar structure, but they lack the myristoylation signal. Here we demonstrate that Sik and BRK associate with the RNA binding protein Sam68 (Src associated during mitosis, ...

... not retard or accelerate the pathogenesis of autoimmune-lymphoproliferative disease in three genetically distinct mouse models of systemic lupus. ...

Translational control plays a crucial role during gametogenesis in organisms as different as worms and mammals. Mouse knockout models have highlighted the essential function of many RNA-binding proteins during spermatogenesis. Herein we have investigated the expression and function during mammalian male meiosis of Sam68, an RNA-binding protein implicated ...

Moxidectin has been used safely as an antiparasitic in many animal species, including for the eradication of the mouse fur mite, Mycoptes musculinus. Although no side effects of moxidectin have previously been reported to occur in mice, 2 strains of the senescence-accelerated mouse (SAMP8 and SAMR1) sustained considerable mortality ...

Working in Microgravity Environment: A Primer . 09:15-10:15. BREAK. 10:15-10:30 . 3. Space Acceleration Measurement Systems (SAMS)-- RTS. 10:30-11:00 ...

Full-text PDF available upon request from http://www.sti.nasa.gov. Select Order Information. 14. ABSTRACT. The Space Acceleration Measurement System (SAMS) ...

... 1 Jul 69-30 Jun 71,. Corporate Author : GEORGIA UNIV EXPERIMENT DIV OF FOOD SCIENCE. Personal Author(s) : Cecil,Sam R. ...

Increased mitogen-activated protein kinase (MAPK) activity correlates with a more malignant hepatocellular carcinoma (HCC) phenotype. There is a reciprocal regulation between p44/42 MAPK (extracellular signal-regulated kinase [ERK]1/2) and the dual-specificity MAPK phosphatase MKP-1/DUSP1. ERK phosphorylates DUSP1, facilitating its proteasomal degradation, whereas DUSP1 inhibits ERK activity. ...

The Microgravity Science and Applications Division's (MSAD) program to record and analyze the Shuttle's vibration environment is reviewed. This program provides microgravity science investigators with time and frequency analyses of the acceleration environment during their experiments' operation. Information is also provided for future investigators on the expected Shuttle ...

Damage to mitochondria as a result of the intrinsic generation of free radicals is theoretically involved in the processes of cellular aging. Herein, we investigated whether acutely administered melatonin, due to its free radical scavenging activity, would influence mitochondrial metabolism. Mitochondrial respiratory activity and respiratory chain complex I and IV activities in liver mitochondria ...

The maiden voyage of the commercial Spacehab laboratory module onboard the STS-57 mission was integrated with several accelerometer packages, one of which was the Space Acceleration Measurement System (SAMS). The June 21st 1993, launch was the seventh suc...

Volunteer subjects were exposed to accelerations up to +8 Gz for 60 sec. Two separate studies were involved: The USAF-CSU-12/P anti-G garment was compared with the RAF 'mini' anti-G suit, and the M-1 maneuver was evaluated and compared with PPB at the sam...

This report summarizes results of force and moment measurements of the Space Acceleration Measurement System 2 (SAMS 2) Tape Drive Assembly (TDA) over the frequency range from 0.35 Hz to 256 Hz for steady state operations including write, read, rewind, an...

The effect of +2 Gz and +2 Gx acceleration for 30 min on the peripheral venous ADH levels in human subjects was studied on the United States Air Force-SAM human centrifuge. A mean rise in the blood ADH level of 2.97 micro U/ml (P

Qualitative urinalysis using Multistix reagent strips for the detection of urinary pH, protein, glucose, bilirubin, blood, ketone, urobilinogen and creatinine can be carried out with a few drops of mouse urine. The use of metabolic cages is not practical for such qualitative studies particularly when several animals are involved. Here we describe two different methods for ...

Much of southern and eastern Australia including Queensland have experienced rainfall declines over recent decades affecting agricultural production and accelerating water infrastructure development. Rainfall declines from southern Australia have now been directly related to changes in the Southern Annular Mode (SAM) and the subtropical ridge. In southern ...

... and A. B. Roberts. Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response. Nat Cell ... ...

... when suspensions are subjected to centrifugation. Influence of centrifugal acceleration, time of centrifugation, and length of the suspension column in quasi-homogeneous centrifugal fields. Cell Biochem Bi...

Feb 26, 2002 ... A useful way to reset a number of settings for a Mac that is behaving strangely. Resets AppleTalk, Volume, Mouse Acceleration, ...

... 2 min per wash) in 10 ml of phosphoric acid per liter of H2O. Filters were then transferred ... ...

, cow Bos taurus, pig Sus scrofa, horse Equus caballus, mouse M. musculus, and rat Rattus norvegicus

The maiden voyage of the commercial Spacehab laboratory module onboard the STS-57 mission was integrated with several accelerometer packages, one of which was the Space Acceleration Measurement System (SAMS). The June 21st 1993, launch was the seventh successful mission for the Office of Life and Microgravity Sciences and Application's (OLMSA) ...

Bicaudal C homologue 1 (Bicc1) knock-out in mice causes polycystic kidney disease and pancreas development defects, including a reduction in insulin-producing ?-cells and ensuing diabetes. We therefore screened 137 patients with renal abnormalities or association of early-onset diabetes and renal disease for genetic alterations in BICC1. We identified two heterozygous mutations, one nonsense in ...

Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder caused by expansion of 55�200 CGG repeats in the 5?-UTR of the FMR1 gene. FXTAS is characterized by action tremor, gait ataxia and impaired executive cognitive functioning. It has been proposed that FXTAS is caused by titration of RNA-binding proteins by the expanded CGG repeats. Sam68 is an ...

The authors review the literature regarding the animal models of osteoporosis in two main groups: The resorption-dominant models (oovariectomy, orchiectomy, limbs imobilization, calcium restriction and use of hormonies) and another group, the formation-deficit models (senil rats, SAM mouse, glucocorticoid administration or limbs imobilization. PMID:9435401

Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Homocysteine (Hcy) metabolism involves multiple enzymes; however, tissue Hcy metabolism and its relevance to methylation remain unknown. Here, we established gene expression profiles of 8 Hcy metabolic and 12 methylation enzymes in 20 human and 19 mouse tissues through bioinformatic analysis using ...

of a 100-fold excess (350 g/mL) of bovine serum albumin (BSA, Sigma) for 4 h at 37�C. Following this SAM fluorescence microscopy. Stress fiber formation was used as an indicator of the extent of cell spreading.15 goat-anti-mouse an- tibody (Molecular Probes, Inc.) and rhodamine phalloidin (Molecular Probes, Inc

a trace of the novel virus, called XMRV. Many hoped a 1.5-day workshop* here last week would help resolve a new study that could help resolve whether the presence of XMRV varies with geography or whether differences in how labs prepare and test sam- ples explain the varying results. XMRV, which resembles a mouse

Contact failures in microelectromechanical systems (MEMS) switches prevent widespread use of MEMS technology for current handling in miniature devices. A self-assembled monolayer (SAM) lubricant was applied to MEMS switch surfaces in this paper as a possible approach for preventing contact failure. Chemical and physical processes on SAM lubricated contact ...

DNA damages caused by endogenously produced radicals are closely correlated with aging. Among them, mitochondrial DNA (mtDNA) deletions have been reported as a memory of DNA damage by oxygen radicals. In fact, clinical as well as experimental studies indicated the accumulation of deleted mtDNA in the brain, myocardium and son on, in aged subjects. In our previous work, radioiodinated radical ...

S-Adenosylmethionine (SAM) treatment has anti-inflammatory, cytoprotective effects against endotoxin-induced organ injury. An important component of the anti-inflammatory action of SAM involves down-regulation of the lipopolysaccharide (LPS)-induced transcriptional induction of tumor necrosis factor-? (TNF) expression by monocytes/macrophages. We examined ...

This paper presents a follow-up study where we test the hypothesis that voice input is faster than using keyboard accelerators. We performed a user study which showed that a "voice plus mouse" interface to MacDraw reduced task completion time by 21.23 percent, while keyboard accelerators reduced task completion time by 14.51 percent if ...

Phosphodiesterase 4 (PDE4) is an intracellular enzyme specifically degrading cAMP, a second messenger exerting inhibitory effects on many inflammatory cells. To investigate whether GPD-1116 (a PDE4 inhibitor) prevents murine lungs from developing cigarette smoke-induced emphysema, the senescence-accelerated mouse (SAM) P1 strain was ...

Exact mass libraries of ESI and APCI mass spectra are not commercially available In-house libraries are dependent on CID parameters and are instrument specific. The ability to identify compounds without reliance on mass spectral libraries is therefore more crucial for liquid sam...