There are sound radiobiologic and suggestive clinical rationale for superfractionating the radiotherapeutic regimens employed for the therapy of rapidly growing malignancies. Oat cell carcinoma of the bronchus is such a tumor. The authors report their experience combining aggressive systemic combination chemotherapy with supperfractionated radiotherapy for ...
Energy Citations Database
Burkitt's lymphoma in an African population was treated by radiotherapy to 43 tumor sites with palpable or visible tumors. Early effects of the treatment are evaluated. In nine tumor sites the treatment was given with conventional fractionation (1 treatment per day) with a mean dose of 3100 rad in 17 fractions over 20 days. The results were disappointing. Only 1 of ...
A survey is given of the mathematical and empirical methods allowing to compare different chronological dose distributions; their possibilities and limits are described. The experimental bases of hyper- and superfractionation and the clinical experiences gained hitherto with multiple daily irradiations are communicated; radiotherapy with high individual ...
PubMed
... Descriptors : *LINEAR ACCELERATORS, *MEDICAL EQUIPMENT, ELECTRON ACCELERATORS, RADIOTHERAPY, ELECTRON BEAMS ...
DTIC Science & Technology
The physical, mechanical and dosimetric features of betatrons are described and discussed. Reference is also made to difficulties that may arise and the limitations associated with their employment as electron accelerators in radiotherapy. PMID:828281
This paper outlines technological considerations in the design of accelerator facilities for medical applications. Emphasis is placed on the specific requirements for MARIA, a radioisotope and radiotherapy facility being planned in Edmonton, Canada. The m...
National Technical Information Service (NTIS)
Continuous, hyperfractionated, accelerated radiotherapy (CHART) was devised to give the maximum chance of improving clinical radiotherapy and was based upon available radiobiological evidence. A pilot study, begun in 1985, has now included 210 patients. When comparison is made with previously treated cases, improved results have been ...
Continuous, hyperfractionated, accelerated radiotherapy (CHART) has given high levels of tumour control in advanced head and neck and bronchial carcinomas. In general, late changes have appeared less than after conventional radiotherapy but despite a prediction of reduced risk of spinal cord damage, two cases of radiation myelitis have ...
