... Premarket Approvals with Supporting Documents. -. Home Access HIV-1 Test System. ... Product Information. Label - Home Access HIV-1 Test System (PDF - 2243KB). -. -. ...
Center for Biologics Evaluation and Research (CBER)
... Recall of Home Access and Home Access Express HIV-1 Test System-Home Access Health Corporation. DATE RECALL INITIATED: ...
... Throughout the education session, clients have the option of speaking with an HAHC ... was conducted in the general population, the other in a high-risk population ...
... of their lifestyles and/or financial situations, this ... their results, the demographic and risk profile of ... kits over-the-counter outweigh the potential risks. ...
... Food and Drug Administration, 9200 Corporate Blvd., Rockville, Maryland 20850 within 10 days after the applicant receives or has knowledge of information ...
... Roche Amplicor HIV-1 Monitor Test. ... Product Information. Label - Roche Amplicor HIV-1 Monitor Test (PDF - 3536KB). -. -. Supporting Documents. ...
... Screening; Infectious Disease Tests. -. HIV-1/2. -. Human Immunodeficiency Virus Types 1 & 2 (Anti-HIV-1/2 Assay). Abbott ...
Page 1. Multispot HIV-1/HIV-2 Rapid Test ... For In Vitro Diagnostic Use 25228 50 Tests Page 2. Multispot HIV-1/HIV-2 Rapid Test 2 CONTENTS ...
... COBAS AmpliScreen HIV-1 Test. ... Product Information. HIV - Nucleic Acid Test - COBAS Ampliscreen HIV-1 Test - Package Insert (PDF - 547KB). -. -. Supporting Documents ...
... Accession Number : ADA219364. Title : HIV-1 and Hepatitis B Transmission in Sudan. Descriptive Note : Journal article. ...
DTIC Science & Technology
Page 1. Use of the Recombigen HIV-1 LA Test (2/1/89) ... Subject: Use of the Recombigen HIV-1 LA Test To: All Register Blood and Plasma Establishment ...
... OraQuick ADVANCE Rapid HIV-1/2 Antibody Test. Proper Name: OraQuick ADVANCE Rapid HIV-1/2 Antibody Test Tradename ...
... Medical Device Notification: HIV-1/HIV-2 Plus O EIA Testing Software-DiaSporin, Inc. ... PRODUCT: HIV-1 / HIV-2 Plus O EIA Testing Software. ...
... Premarket Approvals with Supporting Documents. -. MedMira Reveal Rapid HIV-1 Antibody Test. ... Label - MedMira Reveal Rapid HIV-1 Antibody Test (PDF - 192KB). -. -. ...
Page 1. 1 Reveal� Rapid HIV-1 Antibody Test This package insert must be read carefully and completely prior to use of ...
... November 29, 2010 Approval Letter - INSTI HIV-1 Antibody Test Kit Indicated for the detection of antibodies to Human Immunodeficiency Virus Type ...
Page 1. Procleix ® HIV-1/HCV Assay For In Vitro Diagnostic Use 1000 Test Kit, 5000 Test Kit CONTENTS ...
... COBAS AmpliScreen� HIV-1 Test, v.1.5 ... binding regions identical to those of the HIV-1 target sequence ... unique probe binding region that differentiates the HIV-1 ...
Background:Morbidity and mortality patterns among pregnant women and their infants (before antiretroviral therapy was widely available) determines HIV-1 diagnostic, monitoring, and care interventions.Methods:Data from mothers and their infants enrolled in a trial of antibiotics to reduce mother-to-child-transmission of HIV-1 at 4 sub-Saharan African sites ...
PubMed Central
Stanford University researchers have determined that protease inhibitors are effective against HIV-1 subtype C infections. HIV-1 subtype C, while common in Africa and India, is not prevalent in the United States, and the drugs previously had not been tested for their effectiveness against that ...
PubMed
BackgroundIn resource-limited settings, most perinatally HIV-1-infected infants do not receive timely antiretroviral therapy because early HIV-1 diagnosis is not available or affordable.ObjectiveTo assess the performance of a low cost in-house real-time PCR assay to detect ...
... Inc; OraSure HIV-1 Western Blot Kit Epitope, Inc; MedMira Reveal Rapid HIV-1 Antibody Test MedMira Laboratories, Inc; Trinity Biotech ...
... 2 (HIV-2). HIV-1 and HIV-2 are similar in genomic structure, morphology and ... are prevalent in blood or blood products from persons at high risk of ...
... Blood & Blood Products; Approved Products; Licensed Products (BLAs); Blood Donor Screening; Infectious Disease Tests. -. Cambridge Biotech HIV-1 Western Blot Kit ...
The tremendous diversity of human immunodeficiency virus (HIV)-1 strains circulating worldwide has an important impact on almost all aspects of the management of this infection, from the identification of infected persons, through treatment efficacy and monitoring, and prevention strategies such as vaccine design. The areas where ...
The rapid test VIKIA HIV1/2 was evaluated in 210 Angolan subjects infected with multiple HIV-1 subtypes and complex recombinant forms and 225 seronegative individuals. All infected subjects tested positive (100% sensitivity); all seronegative subjects ...
... The previous study was successful in the development of a sensitive, quantitative assay for HIV-1 DNS sequences. The ...
Page 1. Procleix � HIV-1/HCV Assay For In Vitro Diagnostic Use 1000 Test Kit, 5000 Test Kit CONTENTS ...
Given the diversity of human immunodeficiency virus type 1 (HIV-1) subtypes and the emergence of subtypes other than HIV-1 subtype B in the United States, genotypic assays must be capable of delivering sequence data on diverse HIV-1 subtypes. We evaluated the performance of ...
Page 1. Multispot HIV-1/HIV-2 Rapid Test Subject Information Notice It is very important for you to read this brochure before you are tested for HIV. ...
... blue spot whereas most other rapid tests use colloidal gold, producing red ... and specificity of the INSTI� HIV-1 Antibody Test, 195 serum/plasma ...
The 2008 Recommendations for care of the International AIDS Society reaffirmed the importance of both accurate and sensitive viral load assessment, and by necessity, access to viral load assays. HIV-1 viral load testing is considered essential when initiating antiretroviral therapy (ART), when monitoring ART ...
... AD_____ DEVELOPMENT OF AN RNA ASSAY TO ACCESS HIV-I LATENCY ... Development of an RNA Assay to Assess HIV-I Latency ...
... Roche Diagnostics has confirmed that the HIV-1 MONITOR Quantitation Standard (HIM QS) vials in the COBAS AMPLICOR HIV-1 MONITOR Test, v1.5 generate low or no ...
BackgroundFor ? 24 years the AIDS pandemic has claimed ? 30 million lives, causing ? 14,000 new HIV-1 infections daily worldwide in 2003. About 80% of infections occur by heterosexual transmission. In the absence of vaccines, topical microbicides, expected to block virus transmission, offer hope for controlling the pandemic. Antiretroviral ...
... What type of counseling is done for rapid HIV tests? Counseling for rapid HIV tests includes: ... Does this test detect antibodies to HIV-2? ...
... No animal studies were performed using the OraQuick ... if tested, do not return for their test results ... Rapid HIV testing addresses this issue by providing results ...
... This method may be used as an alternative to currently licensed HIV-1 p24 antigen tests for screening Source Plasma. National Genetics Institute is hereby ...
... result, due to the absence of the HIV -1 antibody/antigen complex, is indicated ... Sodium azide forms lead or copper azide in laboratory plumbing and may explode ...
Human Immunodeficiency Virus Type 1 (HIV-1) Group M RNA, HIV-1 Group O RNA, Human Immunodeficiency Virus Type 2 (HIV-2) RNA, Hepatitis ...
With both HIV-1 and HV-2 prevalent in Guinea-Conakry, accurate diagnosis and differentiation is crucial for treatment purposes. Thus, four rapid HIV tests were evaluated for their HIV-1 and HIV-2 diagnostic and discriminative capacity for use in Guinea-Conakry. These included SD Bioline HIV 1/2 ...
Human immunodeficiency virus type 1 (HIV-1) protease (PR) and reverse transcriptase (RT) gene sequences obtained during antiretroviral resistance testing with a commercial genotyping assay (TruGene; Bayer Corp.) were analyzed to assess the utility of these data for detecting and characterizing non-subtype-B ...
We estimated HIV-1 incidence and characterized risk factors associated with recent infection among participants of a mobile HIV voluntary counseling and testing (VCT) pilot program in two communities in Zimbabwe (N = 1096). HIV-1 infection was diagnosed using a parallel rapid ...
... Test contains warnings and precautions, restrictions on the sale, distribution and use ... or Non- Reactive INSTI test result, as well as general information about ...
During 25 years of research since HIV-1 was first identified in Paris, there have been great advances in our understanding of the virus and of the immune system. Practical advances include the early development of diagnostic tests of infection that made blood donation safe, and since 1996, combination anti-retroviral therapy that has ...
HIV-1 viral load determination is a crucial step for monitoring the efficacy of highly active antiretroviral therapy (HAART) and predicts disease progression. Real-time PCR based assays are available for monitoring the viral load. They differ in sensitivity, genomic target region and dynamic range. In this study, the performance of the Roche Cobas Taqman ...
The purpose of this study was to assess whether the LG Anti-HIV 1/2 Plus ELISA (LG Life Sciences, Seoul, Korea), a new third-generation enzyme-linked immunosorbent assay for the detection of HIV infection, has improved sensitivity and specificity in comparison to the other licensed third-generation assays. The sensitivity of the LG ...
BackgroundExpensive CD4 count and viral load tests have failed the intended objective of enabling access to HIV therapy in poor resource settings. It is imperative to develop simple, affordable and non-subjective disease monitoring tools to complement clinical staging efforts of inexperienced health personnel currently manning most healthcare centres ...
... eligible for reentry. The prior memorandum mentioned circumstances which could give rise to false positive results. This test requires ...
... The standard laboratory HIV testing algorithm used in the United States consists of ... after 20 minutes but not more than 60 minutes after the introduction of the ...
... Changes Being Effected." This procedure is not applicable to changes in device design, composition, specifications, circuitry, software or energy source. ...
Clearinghouse bullet Quality Assurance Guidelines for Testing Using the OraQuick Rapid HIV-1 Antibody Test PDF (06/16/2003) Appendices: Government Regulations and Sample Forms...
Science.gov Websites
... test. If you learn that you are infected with HIV, you can take steps to avoid activities that will Page 2. pass it on to others. ...
... to a new lot number of INSTI� test kits � whenever a new shipment of kits is received � when temperature during storage of the kit falls outside of 15°-30 ...
... donor interview); Laboratory testing and deferral (HIV-1, HIV-2, HBV, HCV, HTLV-I, HTLV-II, WNV, syphilis); Deferral registries ...
Every day, 1900 children acquire HIV-1 infection from their mother in Africa. The 25-45% risk of mother-to-child transmission can be reduced in several ways: prevention of sexual transmission for women of child-bearing age, access to HIV-1 testing, reduction of unwanted pregnancies by education of HIV-1-infected ...
The Procleix HIV-1/HCV Assay is a high-throughput nucleic acid test for the simultaneous detection of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) RNA during blood donor screening. This study evaluated the clinical sensitivity of the Procleix assay and assessed the ...
The external subunit of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env), gp120, contains conserved regions that mediate sequential interactions with two cellular receptor molecules, CD4 and a chemokine receptor, most commonly CCR5 or CXCR4. However, antibody accessibility to such regions is hindered by ...
Background & objectives:Information available on HIV-2 and dual infection (HIV-1/2) is limited. This study was carried out among HIV positive individuals in an urban referral clinic in Khar, Mumbai, India, to report on relative proportions of HIV-1, HIV-2 and HIV-1/2 and baseline characteristics, response to and outcomes on antiretroviral treatment ...
BackgroundIncreased access to HIV testing is essential in working towards universal access to HIV prevention and treatment in resource-limited countries. We here evaluated currently used HIV diagnostic tests and algorithms in Cameroon for their ability to correctly identify HIV infections.MethodsWe estimated ...
Initial biologic events that underlie sexual transmission of HIV-1 are poorly understood. To model these events, we exposed human immature Langerhans cells (LCs) within epithelial tissue explants to two primary and two laboratory-adapted HIV-1 isolates. We detected HIV-1Ba-L infection in ...
The COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, version 1.5 (CAP/CA), and the COBAS AMPLICOR HIV-1 MONITOR Test, version 1.5, were compared. CAP/CA reduced and consolidated labor while modestly increasing assay throughput without increased failure rates or direct ...
Semen samples from a donor who seroconverted for human immunodeficiency virus type 1 (HIV-1) during the period that he was donating at our clinic were stored before and after infection. Semen analysis was done on all of these samples before cryopreservation. Retrospectively, both qualitative and quantitative HIV-1 ...
HIV 1-2 Rapid Test Kit, identified also as HIV Self Test Kit; Easy Kit � Home HIV Rapid Test Kit; HIV TEST YOURSELF test kit; Easy Kit � Get Negative ...
... VIII. ... Sensitivity of the Reveal Rapid HIV-1 Antibody Test in the Detection of HIV-1 From Various Geographic Regions The sensitivity of the Reveal ...
... November 7, 2002 Approval Letter. Package Insert (PDF - 238 KB). Summary of Safety and Effectiveness (PDF - 82 KB). -. Related Information. ...
... The human source material used in the preparation of ... Materials Required But Not Provided 1. Disposable glass ... that demonstrate purple color development in the ...
... of data from any clinical investigations or nonclinical laboratory studies involving ... Any significant chemical, physical or other change or deterioration in the ...
... Being Effected." This procedure is not applicable to changes in device design, composition, specifications, circuitry, software or energy source. ...
... HIV-SELECTEST: a new HIV-1 EIA and Rapid test for differential diagnosis of HIV infections in the face of vaccine-induced antibodies. S. Khurana et al. 2006. ...
... Natural History, and Psychological Reactions. ... NATURAL HISTORY, *REACTION(PSYCHOLOGY), TEST ... SEX, ACQUIRED IMMUNE DEFICIENCY ...
... A case-control study demonstrated past positive tuberculin skin test, recent tetanus booster, autoantibodies, and parity were associated with IWBs. ...
... enzyme-linked immunosorbent assay (ELISA), Human Immunodeficiency Virus (HIV), immunofluorescence-assay (IFA), optical density (OD), radioimmunoprecipitation ...
... COBAS AmpliPrep/COBAS TaqMan HIV-1 Test, 48 Tests; COBAS AmpliPrep/COBAS TaqMan Wash Reagent, 5.1 L. Proper ...
A human monoclonal antibody, 41-7 [immunoglobulin G1(kappa)], directed against the transmembrane glycoprotein gp41 of the human immunodeficiency virus type 1 (HIV-1) has been produced by direct fusion of lymph node cells from an HIV-1-infected individual with a human B-lymphoblastoid cell line. The minimal essential epitope for 41-7 was mapped to a ...
BackgroundAt present, there is no effective vaccine or other approved product for the prevention of sexually transmitted human immunodeficiency virus type 1 (HIV-1) infection. It has been reported that women in resource-poor communities use vaginally applied citrus juices as topical microbicides. These easily accessible food products ...
The AIDS pandemic continues. Little is understood about how HIV gains access to permissive cells across mucosal surfaces, yet such knowledge is crucial to the development of successful topical anti-HIV-1 agents and mucosal vaccines. HIV-1 rapidly internalizes and integrates into the mucosal ...
BACKGROUND: Worldwide access to antiretroviral therapy (ART) in low- and middle-income countries has significantly increased. Although this presents better treatment options for HIV-infected individuals, the challenge of monitoring ART in these settings still remains. OBJECTIVE: To investigate efficient and cost-effective criteria for assessing ART failure among ...
The plasma human immunodeficiency virus (HIV) RNA load is used in the clinical routine for the monitoring of HIV infection and the patient's response to antiretroviral therapy. Other body fluids or dried blood spots (DBS) can be used, however, to assess the level of viremia. The use of DBS may be especially helpful for the monitoring of HIV-infected patients in resource-poor settings, where ...
BackgroundSince 1986, northern Uganda has been severely affected by civil strife with most of its population currently living internally displaced in protected camps. This study aims at estimating the HIV-1 prevalence among this population and the factors associated with infection.MethodsIn June-December 2005, a total of 3051 antenatal clinics attendees in Gulu, Kitgum and Pader districts were ...
BackgroundWe conducted secondary data analyses of a clinical trial (HIVNET 024) to assess risk factors for late postnatal transmission (LPT) of HIV-1 through breastfeeding.MethodsData regarding live born, singleton infants of HIV-1-infected mothers were analyzed. The timing of HIV-1 transmission through 12 months after birth was defined as: in utero (positive ...
Human immunodeficiency virus type 1 (HIV-1) can be transmitted through breast-feeding and through contaminated blood donations. Copper has potent biocidal properties and has been found to inactivate HIV-1 infectivity. The objective of this study was to determine the capacity of copper-based filters to inactivate ...
Altered cytokine production in human immunodeficiency virus 1 (HIV-1) infection is well documented and cytokine modulators are currently under investigation as possible therapeutic agents. We tested the ability of Ridostin (dsRNA preparation derived from S. cervisiae) to inhibit HIV-1 ...
Dendritic cells (DC) are the most potent antigen presenting cells whose ability to interact with T cells, B cells and NK cells has led to their extensive use in vaccine design. Here, we designed a DC-based HIV-1 vaccine using an attenuated rabies virus vector expressing HIV-1 Gag (RIDC-Gag). To ...
IntroductionMore new HIV-1 infections occur within stable HIV-1-discordant couples than in any other group in Africa, and sexually transmitted infections (STIs) may increase transmission risk among discordant couples, accounting for a large proportion of new HIV-1 ...
Abstract Background: Human immunodeficiency virus type-1 (HIV-1) RNA viral load is a surrogate marker that is routinely used to determine indications for, and monitor the effectiveness of HIV-1 treatment. We developed three reagents for potential use in routine quality control of HIV-1 RNA quantitative assays. In this report, we compare the stability of ...
Lymphoid tissue is the main reservoir of HIV-1 in infected individuals. In this study the COBAS� TaqMan� HIV-1 test was evaluated for use with the High Pure System (HPS), for quantifying HIV-1 RNA in infected cells and lymphoid tissue specimens. Serial dilutions of 8E5-LAV1 infected T-cells ...
BackgroundHigh plasma HIV-1 RNA concentrations are associated with increased risk of HIV-1 transmission. Initiation of antiretroviral therapy (ART) reduces plasma HIV-1 concentrations, but little empiric data are available on the rate of sexual HIV-1 transmission from ...
... for use as a point-of-care test to aid in the diagnosis of infection with HIV-1 and HIV-2. This test is suitable for use in multi-test algorithms designed for ...
The objective of this study was to compare the performance of the NucliSENS EasyQ HIV-1 v1.2 platform (bioM�rieux, France) to the Amplicor HIV-1 DNA test v1.5 (Roche Molecular Systems, Switzerland) in detecting HIV-1 infection in infants using ...
One of the cell types first encountered by human immunodeficiency virus type 1 (HIV-1) following sexual transmission are dendritic cells (DC). DC capture HIV-1 through C-type lectin receptors, of which the best studied example is DC-SIGN, which mediates HIV-1 ...
We tested whether human immunodeficiency virus type 1 (HIV-1) could be differentiated from HIV-2 by a reverse transcriptase (RT)-typing assay that measured the reduction of enzyme activity owing to specific antibody. RT-inhibiting antibody was examined for HIV type specificity by a new nonradioisotopic RT assay. Antibodies from four ...
... 8 x 0.1 mL (HIV-1 Manganese Solution, version 1.5) < 2% Manganese Acetic acid ... S: 53-45 Avoid exposure � obtain special instructions before use. ...
BackgroundThe aim of this study was to develop an economical 'in-house' single round polymerase chain reaction (PCR) assay using filter paper-dried blood spots (FP-DBS) for early infant HIV-1 diagnosis and to evaluate its performance in an African setting.MethodsAn 'in-house' single round PCR assay that targets conserved regions in the HIV-1 polymerase ...
... This mix ture can produce a highly toxic gas. ... Positive Primary pools are traced to the positive individual using an overlapping pool testing matrix. ...
... in which high rates of virus production and infection ... dye due to Förster-type energy transfer effects ... 0.5% sodium hypochlorite in deionized or distilled water. ...
... Austria Indonesia Philippines Belarus Ireland Poland Belgium Israel Qatar Canada Japan Russia Chile Korea Saudi Arabia Cyprus Kuwait Slovenia ...
... acid amplification test for the quantitation of HIV-l RNA in ... T-Cell Lymphotropic viruss type 1 Human T-Cell Lymphotropic viruss ... 500 cells/uL) and ...
... Capture antigens may be peptides, proteins, fusion peptides or viral lysates. ... Rapid tests may also be used as part of a diagnostic testing algorithm. ...
... visually rather than with an instrument, 2) the OraQuick ® ADVANCE test uses colloidal gold as the ... 0 1 Interfering Substances (n = 199) Elevated Bilirubin ...
... 1 Genotyping Kit and OpenGene DNA sequencing system. ... CB Test Certificate, Certificate Number CA 1622 / Test ... armonic Current emissions (Input current < 16 Amps ...
... (a) Human Immunodeficiency Virus (HIV) �(1) Clinically indicated...guidelines, that the inmate is at risk for HIV infection. If the inmate refuses testing...that the inmate may have transmitted the HIV infection, whether intentionally...
Code of Federal Regulations, 2011
Code of Federal Regulations, 2010
The use of rapid human immunodeficiency virus (HIV) antibody tests can help reduce the number of individuals positive for HIV who are unaware of their infection. Although several studies have demonstrated that the sensitivity and specificity of rapid HIV tests are comparable to those of enzyme immunoassays, none have addressed the rapidity with which these ...
The analytical performance of the NucliSens HIV-1 QT assay, a highly sensitive test based on nucleic acid sequence-based amplification technology, was evaluated in a multicenter trial. Assay specificity was evaluated with 502 plasma (EDTA) specimens from human immunodeficiency virus type 1 ...
Small interfering RNAs (siRNAs) have been shown to effectively inhibit human immunodeficiency virus type 1 (HIV-1) replication in vitro. The mechanism(s) for this inhibition is poorly understood, as siRNAs may interact with multiple HIV-1 RNA species during different steps of the retroviral life cycle. To define ...
There is an urgent need for low-cost, simple, and accurate human immunodeficiency virus type 1 (HIV-1) viral load monitoring technologies in resource-limited settings, particularly at the time of the scaling-up of first and second-line highly active antiretroviral therapies. This review describes the main characteristics and advantages/ disadvantages of ...
Human immunodeficiency virus type 1 (HIV-1) infects both activated CD4+ T cells and macrophages. We tested if liquid chromatography-tandem mass spectrometry (LC-MS/MS) technology can monitor metabolic alterations induced by HIV-1 in the infected cells. Here we monitored glucose uptake and conducted LC-MS/MS-based metabolomic analysis ...
In the absence of a vaccine, there is an urgent need for the development of safe and effective topical microbicides to prevent the sexual transmission of human immunodeficiency virus type 1 (HIV-1). In this study, we proposed to develop a novel class of microbicides using syndecan as the antiviral agent. Specifically, we generated a soluble syndecan-Fc ...
The extent to which human immunodeficiency virus (HIV-1) infection impacts on the ability to mount an effective immune response to HPV is unknown, but is relevant in planning HPV vaccine strategies for HIV-1 infected individuals. This longitudinal study investigated changes shortly after HIV-1 seroconversion on ...
BACKGROUND: Automated HIV-1 RNA extraction and its quantification by real-time PCR assays provide improved sample processing and better analytical performances. The new Artus HIV-1 RealTime assay can be performed after automated extraction with the Qiagen Qiasymphony robot. OBJECTIVES AND STUDY DESIGN: To evaluate ...
The persistence of latent HIV-infected cellular reservoirs represents the major hurdle to virus eradication on patients treated with HAART. It has been suggested that successful depletion of such latent reservoirs will require a combination of therapeutic agents that can specifically and efficiently act on cells harboring latent HIV-1 provirus. Using ...
This year we continued to identify novel antibodies against HIV-1 from our previously constructed and from newly constructed libraries from patients with HIV-1 infection. The major accomplishments are summarized below. 1) We have previously shown that small-size engineered antibodies can target highly conserved epitopes not accessible ...
Cancer.gov
AbstractAlthough many interactions between HIV-1 and human proteins have been reported in the scientific literature, no publicly accessible source for efficiently reviewing this information was available. Therefore, a project was initiated in an attempt to catalogue all published interactions between ...
ObjectiveOur objectives were to assess clinical signs and diagnoses associated with primary HIV-1 infection among infants.MethodsWe analyzed data from a clinical trial (HPTN 024) in sub-Saharan Africa. Study visits were conducted at birth, at 4�6 weeks, and at 3, 6, 9, and 12 months. The study population comprised live born, singleton, first born infants ...
BackgroundIn women, single-dose nevirapine for prophylaxis against mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) selects for nevirapine-resistant HIV-1, which subsequently decays rapidly. We hypothesized that the selection, acquisition, and decay of nevirapine-resistant ...
Bleaching of syringes has been advocated to prevent HIV transmission among injection drug users (IDUs). Several reports indicate that IDUs use household products to disinfect syringes instead of bleach. To test their disinfection efficacy, we performed syringe-rinsing simulations with a range of agents used by IDUs trying to disinfect their syringes. No viable ...
... Urgent Product Correction - Bio-Rad Laboratories Multispot HIV-1/HIV-2 Rapid Test - Bio-Rad Laboratories. DATE NOTIFICATION INITIATED: ...
... Adenovirus type 2, Epstein Barr Virus, Human Papilloma Virus, Type 16. Adenovirus type 3, Hepatitis A Virus, Human Papilloma Virus, Type 18. ...
... What should you know about HIV and AIDS? How can you become infected with HIV? ... Where can you get more information about HIV and AIDS? ...
... An AlDS service organization near you can also be a good source for information, education, and help. ~Ddnde puedo obtener m8s informacidn? ...
... The virus weakens the body's ability to fight off infections. As a result, people with AlDS develop serious infections and cancers. ...
... Increased frequency of the occurrence of "blue foci" may lead to elevated and/or observed out of sequence optical density readings in the microwell plate ...
... DO NOT allow the person to swab the roof of the mouth, the inside ... any of the following anticoagulants: EDTA (lavender top), sodium heparin (green top), sodium ...
... 2. The United States Food and Drug Administration has ... v/v dilution of household bleach, prepared fresh daily) or ... Place the tip of the pipette into the specimen ...
... March 26, 2004 Approval Letter. Control Kit (PDF - 130 KB). Subject Information (PDF - 257 KB). Approval Date: 3/19/2004. ...
... Before making any change affecting the safety or effectiveness of the device, you must submit a PMA supplement or an alternate submission (30-day notice) in ...
... OraSure Technologies will provide the FDA/CBER with Western Blot results for ... Hira L. Nakhasi, Ph.D. Director Division of Emerging and Transfusion Transmitted ...
... Mr. Hermes Chan MedMira Labs 155 Chain Lake Drive, Bayers Lake Halifax, Nova ... Hira L. Nakhasi, Ph.D. Director Division of Emerging and Transfusion Transmitted ...
... a waiting period of one year and may be reentered if a current donation from the donor is found to be non-reactive using a group O sensitive anti-HIV-1/2 test. ...
... with the Act. If you have any questions regarding this matter, you may contact Anna M. Flynn at (301) 827-6201. Please be advised ...
... MATERIALS REQUIRED BUT NOT PROVIDED Timer or watch capable of timing 20 to 40 minutes Latex, vinyl or nitrile disposable gloves Biohazard waste container Clean ...
... of the virus in patients causes the immune system to elicit the production of antibodies. ... in the TEST (T) area producing a pink/purple line. ...
Many serologic techniques are available for the detection of HIV-1 infection, but their diagnostic performances have been reported to vary depending on the testing situations. We evaluated eight different serologic assays for detecting HIV-1 antibody in s...
National Technical Information Service (NTIS)
1 (HIV-1). Both are examples where selection has favored diversity. Its action is restricted. A splice variant of it is highly expressed in human testes and in ejaculated spermatozoa (HUANG et al. 2004
E-print Network
... OraQuick Rapid HIV-1/2 Antibody Test, Addition to the intended use statement to include detection of antibodies to HIV-2, OraSure Technologies 150 Webster Street ...
... HIV-1 Genotyping Kit & Open Gene DNA Sequencing System, HIV test kit used in the detection of genomic mutations, BK020005, Visible Genetics, Inc 700 Bay Street ...
We evaluated the effects of time, temperature, freezing, and thawing on the cerebrospinal fluid viral load by using the Roche AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive). While a statistically significant decrease from the baseline was observed at 24 h, but not at 6 or 12 h, and with one freeze-thaw cycle, all changes ...
A multi-test sequential algorithm based on Rapid/Simple (R/S) assays was applied for the diagnosis of HIV infection among participants in a phase 3 microbicide effectiveness trial. HIV testing was performed on finger-prick blood samples from patients after their enrollment in the trial. The specimens were tested in a serial procedure ...
The ViroSeq (Celera Diagnostics) and Trugene (Bayer HealthCare) HIV-1 genotyping systems are widely used today in world clinical practice to detect drug resistance mutations resulting from ineffective treatment for HIV infection. Only the former test has gained acceptance. The present study has compared ViroSeq and Trugene genotyping ...
An association between past exposure to tuberculosis (TB) and infection with human immunodeficiency virus type 1 (HIV-1) was investigated using a case-control design among a 6-week sample of 698 male inmates consecutively admitted to the Maryland State prison system. Based on Mantoux testing and measurement of anti-HIV-1, we found a ...
Based on an established common pharmacophore of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNTTIs), a series of quinolin-2-one derivatives were synthesized and assayed for their in vitro activities against HIV-1 reverse transcriptase (RT) for the first time. Some of the tested compounds were active against ...
The relationship of self-reported cognitive, motor, and affective complaints to actual neuropsychological functioning was explored in a cohort of predominantly symptomatic HIV-1 seropositive individuals. Ninety-two symptomatic HIV-1 infected subjects were questioned about complaints common in HIV infection and were ...
The human immune system has evolved to recognize antigenic diversity, a strength that has been harnessed by vaccine developers to combat numerous pathogens (e.g. pneumococcus, influenza virus, rotavirus). In each case, vaccine cocktails were formulated to include antigenic variants of the target. To combat HIV-1 diversity, we assembled a cocktail vaccine ...
HIV-1 infection of neonates results in an extended acute period of virus replication, frequent neurological problems and reduced survival compared to adults. In adults, R5 viruses mainly infect CCR5(+) CD4(+) memory T-cells. In neonates, CCR5(+) memory T-cells form a substantially smaller fraction of total lymphocytes. We therefore ...
