Sample records for accessibility global gateway

  1. Accessibility: global gateway to health literacy.

    PubMed

    Perlow, Ellen

    2010-01-01

    Health literacy, cited as essential to achieving Healthy People 2010's goals to "increase quality and years of healthy life" and to "eliminate health disparities," is defined by Healthy People as "the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions." Accessibility, by definition, the aforementioned "capacity to obtain," thus is health literacy's primary prerequisite. Accessibility's designation as the global gateway to health literacy is predicated also on life's realities: global aging and climate change, war and terrorism, and life-extending medical and technological advances. People with diverse access needs are health professionals' raison d'être. However, accessibility, consummately cross-cultural and universal, is virtually absent as a topic of health promotion and practice research and scholarly discussion of health literacy and equity. A call to action to place accessibility in its rightful premier position on the profession's agenda is issued.

  2. Ad Hoc Access Gateway Selection Algorithm

    NASA Astrophysics Data System (ADS)

    Jie, Liu

    With the continuous development of mobile communication technology, Ad Hoc access network has become a hot research, Ad Hoc access network nodes can be used to expand capacity of multi-hop communication range of mobile communication system, even business adjacent to the community, improve edge data rates. For mobile nodes in Ad Hoc network to internet, internet communications in the peer nodes must be achieved through the gateway. Therefore, the key Ad Hoc Access Networks will focus on the discovery gateway, as well as gateway selection in the case of multi-gateway and handover problems between different gateways. This paper considers the mobile node and the gateway, based on the average number of hops from an average access time and the stability of routes, improved gateway selection algorithm were proposed. An improved gateway selection algorithm, which mainly considers the algorithm can improve the access time of Ad Hoc nodes and the continuity of communication between the gateways, were proposed. This can improve the quality of communication across the network.

  3. Access control mechanism of wireless gateway based on open flow

    NASA Astrophysics Data System (ADS)

    Peng, Rong; Ding, Lei

    2017-08-01

    In order to realize the access control of wireless gateway and improve the access control of wireless gateway devices, an access control mechanism of SDN architecture which is based on Open vSwitch is proposed. The mechanism utilizes the features of the controller--centralized control and programmable. Controller send access control flow table based on the business logic. Open vSwitch helps achieve a specific access control strategy based on the flow table.

  4. Global Document Delivery, User Studies, and Service Evaluation: The Gateway Experience

    ERIC Educational Resources Information Center

    Miller, Rush; Xu, Hong; Zou, Xiuying

    2008-01-01

    This study examines user and service data from 2002-2006 at the East Asian Gateway Service for Chinese and Korean Academic Journal Publications (Gateway Service), the University of Pittsburgh. Descriptive statistical analysis reveals that the Gateway Service has been consistently playing the leading role in global document delivery service as well…

  5. BSV Gateway Description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deshpande, Alina

    Los Alamos National Laboratory (LANL) is part of that worldwide team and has been developing state of the art information systems to aid the global health community. For instance, in 2014 LANL announced the release of the LANL Biosurveillance (BSV) Gateway. The site provides information about ongoing biosurveillance research projects and capabilities at LANL, and provides access to a host of LANL-developed biosurveillance tools and resources. We are seeking feedback on this gateway and would like to ask interested folk to offer comments and suggestions after they have perused the BSV website.

  6. WorldWideScience.org: the global science gateway.

    PubMed

    Fitzpatrick, Roberta Bronson

    2009-10-01

    WorldWideScience.org is a Web-based global gateway connecting users to both national and international scientific databases and portals. This column will provide background information on the resource as well as introduce basic searching practices for users.

  7. Tao of Gateway: Providing Internet Access to Licensed Databases.

    ERIC Educational Resources Information Center

    McClellan, Gregory A.; Garrison, William V.

    1997-01-01

    Illustrates an approach for providing networked access to licensed databases over the Internet by positioning the library between patron and vendor. Describes how the gateway systems and database connection servers work and discusses how treatment of security has evolved with the introduction of the World Wide Web. Outlines plans to reimplement…

  8. SEDAC information gateway plan V(1)

    NASA Technical Reports Server (NTRS)

    Chen, Robert S. (Compiler)

    1995-01-01

    This annual update of the Information Gateway Plan incorporates changes recommended by the Socioeconomic Data and Applications Center (SEDAC) User Working Group (UWG) and reflects comments and suggestions from users, collaborators, and the Contracting Officer Technical Representative (COTR). The Information Gateway Plan is a concise and specific plan that outlines SEDAC activities and services in support of the earth and social sciences and other user communities. The SEDAC Information Gateway effort is a primary means by which the Earth Observing System Data and Information System (EOSDIS) can link meaningfully with a broad range of social science data sources and users in ways that lead to tangible benefits to the American people. The SEDAC Information Gateway provides interdisciplinary access to socioeconomic and physical science data and information resources held by SEDAC and numerous other institutions and networks around the world. The Plan describes the areas of research of earth scientists and socioeconomic scientists where interchange of data and information is most needed. It sets guidelines for the continued development of SEDAC's directory of social science datasets and establishes priorities for efforts to make data held by SEDAC or accessible through SEDAC available to the user community. The Plan also describes the means by which the SEDAC user community can access information products specified by the SEDAC Data and Applications Development Plan (DADP). Among other major activities, SEDAC will continue to enhance and operate a directory capability, interoperable with the Global Change Master Directory, that provides the socioeconomic community with information about earth science products and the earth science research community with information about socioeconomic data. The Information Gateway also serves as a unique and powerful access pathway for a wide range of users and potential users of socioeconomic and earth science data, including

  9. Global Magnetospheric Imaging from the Deep Space Gateway in Lunar Orbit

    NASA Astrophysics Data System (ADS)

    Chua, D. H.; Socker, D. G.; Englert, C. R.; Carter, M. T.; Plunkett, S. P.; Korendyke, C. M.; Meier, R. R.

    2018-02-01

    We propose to use the Deep Space Gateway as an observing platform for a magnetospheric imager that will capture the first direct global images of the interface between the incident solar wind and the Earth's magnetosphere.

  10. Knowledge Gateways: The Building Blocks.

    ERIC Educational Resources Information Center

    Hawkins, Donald T.; And Others

    1988-01-01

    Discusses the need for knowledge gateway systems to provide access to scattered information and the use of technologies in gateway building, including artificial intelligence and expert systems, networking, online retrieval systems, optical storage, and natural language processing. The status of four existing gateways is described. (20 references)…

  11. A case study of the Secure Anonymous Information Linkage (SAIL) Gateway: A privacy-protecting remote access system for health-related research and evaluation☆

    PubMed Central

    Jones, Kerina H.; Ford, David V.; Jones, Chris; Dsilva, Rohan; Thompson, Simon; Brooks, Caroline J.; Heaven, Martin L.; Thayer, Daniel S.; McNerney, Cynthia L.; Lyons, Ronan A.

    2014-01-01

    With the current expansion of data linkage research, the challenge is to find the balance between preserving the privacy of person-level data whilst making these data accessible for use to their full potential. We describe a privacy-protecting safe haven and secure remote access system, referred to as the Secure Anonymised Information Linkage (SAIL) Gateway. The Gateway provides data users with a familiar Windows interface and their usual toolsets to access approved anonymously-linked datasets for research and evaluation. We outline the principles and operating model of the Gateway, the features provided to users within the secure environment, and how we are approaching the challenges of making data safely accessible to increasing numbers of research users. The Gateway represents a powerful analytical environment and has been designed to be scalable and adaptable to meet the needs of the rapidly growing data linkage community. PMID:24440148

  12. Global Lunar Topography from the Deep Space Gateway for Science and Exploration

    NASA Astrophysics Data System (ADS)

    Archinal, B.; Gaddis, L.; Kirk, R.; Edmundson, K.; Stone, T.; Portree, D.; Keszthelyi, L.

    2018-02-01

    The Deep Space Gateway, in low lunar orbit, could be used to achieve a long standing goal of lunar science, collecting stereo images in two months to make a complete, uniform, high resolution, known accuracy, global topographic model of the Moon.

  13. A case study of the Secure Anonymous Information Linkage (SAIL) Gateway: a privacy-protecting remote access system for health-related research and evaluation.

    PubMed

    Jones, Kerina H; Ford, David V; Jones, Chris; Dsilva, Rohan; Thompson, Simon; Brooks, Caroline J; Heaven, Martin L; Thayer, Daniel S; McNerney, Cynthia L; Lyons, Ronan A

    2014-08-01

    With the current expansion of data linkage research, the challenge is to find the balance between preserving the privacy of person-level data whilst making these data accessible for use to their full potential. We describe a privacy-protecting safe haven and secure remote access system, referred to as the Secure Anonymised Information Linkage (SAIL) Gateway. The Gateway provides data users with a familiar Windows interface and their usual toolsets to access approved anonymously-linked datasets for research and evaluation. We outline the principles and operating model of the Gateway, the features provided to users within the secure environment, and how we are approaching the challenges of making data safely accessible to increasing numbers of research users. The Gateway represents a powerful analytical environment and has been designed to be scalable and adaptable to meet the needs of the rapidly growing data linkage community. Copyright © 2014 The Aurthors. Published by Elsevier Inc. All rights reserved.

  14. Development of ISO connection-oriented/correctionless gateways

    NASA Technical Reports Server (NTRS)

    Landweber, Lawrence H.

    1991-01-01

    The project had two goals, establishment of a gateway between French and U.S. academic networks and studies of issues related to the development of ISO connection-oriented/connectionless (CO/CL) gateways. The first component involved installation of a 56K bps line between Princeton Univ. and INRIA in France. The end-points of these lines were connected by Vitalink link level bridges. The Princeton end was then connected to the NSFNET via the John Von Neumann Supercomputer Center. The French end was connected to Transpac, the French X.25 public data network and to the French IP research internet. U.S. users may communicate with users of the French internet by e-mail and may access computational and data resources in France by use of remote login and file transfer. The connection to Transpac enables U.S. users to access the SIMBAD astronomical database outside of Paris. Access to this database from the U.S. can be via TCP/IP or DECNET (via a DECNET to TCP/IP gateway) protocols utilizing a TCP/IP to X.25 gateway developed and operated by INRIA. The second component of the project involved experiments aimed at understanding the issues involved is ISO CO/CL gateways. An experimental gateway was developed at Wisconsin and a preliminary report was prepared. Because of the need to devote most resources to the first component of the project, work in this area did not go beyond development of a prototype gateway.

  15. A science data gateway for environmental management: A SCIENCE DATA GATEWAY FOR ENVIRONMENTAL MANAGEMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agarwal, Deborah A.; Faybishenko, Boris; Freedman, Vicky L.

    Science data gateways are effective in providing complex science data collections to the world-wide user communities. In this paper we describe a gateway for the Advanced Simulation Capability for Environmental Management (ASCEM) framework. Built on top of established web service technologies, the ASCEM data gateway is specifically designed for environmental modeling applications. Its key distinguishing features include: (1) handling of complex spatiotemporal data, (2) offering a variety of selective data access mechanisms, (3) providing state of the art plotting and visualization of spatiotemporal data records, and (4) integrating seamlessly with a distributed workflow system using a RESTful interface. ASCEM projectmore » scientists have been using this data gateway since 2011.« less

  16. Lunar Global Heat Flow Mapping with a Reusable Lander Deployed from the Deep Space Gateway Spacecraft

    NASA Astrophysics Data System (ADS)

    Nagihara, S.; Zacny, K.; Chu, P.; Kiefer, W. S.

    2018-02-01

    We propose to equip the Deep Space Gateway spacecraft with a reusable lander that can shuttle to and from the lunar surface, and use it for collecting heat flow measurements globally on the lunar surface.

  17. NASA gateway requirements analysis

    NASA Technical Reports Server (NTRS)

    Duncan, Denise R.; Doby, John S.; Shockley, Cynthia W.

    1991-01-01

    NASA devotes approximately 40 percent of its budget to R&D. Twelve NASA Research Centers and their contractors conduct this R&D, which ranges across many disciplines and is fueled by information about previous endeavors. Locating the right information is crucial. While NASA researchers use peer contacts as their primary source of scientific and technical information (STI), on-line bibliographic data bases - both Government-owned and commercial - are also frequently consulted. Once identified, the STI must be delivered in a usable format. This report assesses the appropriateness of developing an intelligent gateway interface for the NASA R&D community as a means of obtaining improved access to relevant STI resources outside of NASA's Remote Console (RECON) on-line bibliographic database. A study was conducted to determine (1) the information requirements of the R&D community, (2) the information sources to meet those requirements, and (3) ways of facilitating access to those information sources. Findings indicate that NASA researchers need more comprehensive STI coverage of disciplines not now represented in the RECON database. This augmented subject coverage should preferably be provided by both domestic and foreign STI sources. It was also found that NASA researchers frequently request rapid delivery of STI, in its original format. Finally, it was found that researchers need a better system for alerting them to recent developments in their areas of interest. A gateway that provides access to domestic and international information sources can also solve several shortcomings in the present STI delivery system. NASA should further test the practicality of a gateway as a mechanism for improved STI access.

  18. Remote Sensing Information Gateway

    EPA Pesticide Factsheets

    Remote Sensing Information Gateway, a tool that allows scientists, researchers and decision makers to access a variety of multi-terabyte, environmental datasets and to subset the data and obtain only needed variables, greatly improving the download time.

  19. 77 FR 21996 - Certain Equipment for Communications Networks, Including Switches, Routers, Gateways, Bridges...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-778] Certain Equipment for Communications Networks, Including Switches, Routers, Gateways, Bridges, Wireless Access Points, Cable Modems, IP Phones... networks, including switches, routers, gateways, bridges, wireless access points, cable modems, IP phones...

  20. Design of smart home gateway based on Wi-Fi and ZigBee

    NASA Astrophysics Data System (ADS)

    Li, Yang

    2018-04-01

    With the increasing demand for home lifestyle, the traditional smart home products have been unable to meet the needs of users. Aim at the complex wiring, high cost and difficult operation problems of traditional smart home system, this paper designs a home gateway for smart home system based on Wi-Fi and ZigBee. This paper first gives a smart home system architecture base on cloud server, Wi-Fi and ZigBee. This architecture enables users to access the smart home system remotely from Internet through the cloud server or through Wi-Fi at home. It also offers the flexibility and low cost of ZigBee wireless networking for home equipment. This paper analyzes the functional requirements of the home gateway, and designs a modular hardware architecture based on the RT5350 wireless gateway module and the CC2530 ZigBee coordinator module. Also designs the software of the home gateway, including the gateway master program and the ZigBee coordinator program. Finally, the smart home system and home gateway are tested in two kinds of network environments, internal network and external network. The test results show that the designed home gateway can meet the requirements, support remote and local access, support multi-user, support information security technology, and can timely report equipment status information.

  1. GATEWAY - COMMUNICATIONS GATEWAY SOFTWARE FOR NETEX, DECNET, AND TCP/IP

    NASA Technical Reports Server (NTRS)

    Keith, B.

    1994-01-01

    The Communications Gateway Software, GATEWAY, provides process-to-process communication between remote applications programs in different protocol domains. Communicating peer processes may be resident on any paired combination of NETEX, DECnet, or TCP/IP hosts. The gateway provides the necessary mapping from one protocol to another and will facilitate practical intermachine communications in a cost effective manner by eliminating the need to standardize on a single protocol or the need to implement multiple protocols in the host computers. The purpose of the gateway is to support data transfers between application programs on different host computers using different protocols. The gateway computer must be physically connected to both host computers and must contain the system software needed to use the communication protocols of both host computers. The communication process between application partners can be divided into three phases: session establishment, data transfer, and session termination. The communication protocols supported by GATEWAY (DECnet, NETEX, and TCP/IP) have addressing mechanisms that allow an application to identify itself and distinguish among other applications on the network. The exact form of the address varies depending on whether an application is passively offering (awaiting the receipt of a network connection from another network application) or actively connecting to another network. When the gateway is started, GATEWAY reads a file of address pairs. One of the address pairs is used by GATEWAY for passively offering on one network while the other address in the pair is used for actively connecting on the other network establishing the session. Now the two application partners can send and receive data in a manner appropriate to their home networks. GATEWAY accommodates full duplex transmissions. Thus, if the application partners are sophisticated enough, they can send and receive simultaneously. GATEWAY also keeps track of the number

  2. The DoD Gateway Information System (DGIS): The DoD Microcomputer User's Gateway to the World.

    ERIC Educational Resources Information Center

    Kuhn, Allan D.; Cotter, Gladys A.

    1988-01-01

    Describes the U.S. Department of Defense (DoD) Gateway Information System, which provides communications capabilities and access to online databases for DoD microcomputer end-users. Functions, structure, development, and artificial intelligence applications of the system are discussed. (11 references) (MES)

  3. The spatial data and knowledge gateways at the International Water Management Institute (IWMI)

    NASA Astrophysics Data System (ADS)

    Thenkabail, P. S.; Biradar, C. M.; Noojipady, P.; Islam, A.; Velpuri, M.; Vithanage, J.; Kulawardhana, W.; Li, Yuan Jie; Dheeravath, V.; Gunasinghe, S.; Alankara, R.

    2006-10-01

    In this paper we discuss spatial data and knowledge base (SDKB) gateway portals developed by the International Water Management Institute (IWMI). Our vision is to generate and/or facilitate easy and free access to state-of-art SDKB of excellence globally. Our mission is to make SDKB accessible online, globally, for free. The IWMI data storehouse pathway (IWMIDSP; http://www.iwmidsp.org) is a pathfinder global public good (GPG) portal on remote sensing and GIS (RS/GIS) data and products with specific emphasis on river basin data, but also storing valuable data on Nations, Regions, and the World. A number of other specialty GPG portals have also been released. These include Global map of irrigated area (http://www.iwmigiam.org), Drought monitoring system for southwest Asia (http://dms.iwmi.org), Tsunami satellite sensor data catalogue (http://tsdc.iwmi.org), and Knowledge base system (KBS) for Sri Lanka (http://www.iwmikbs.org). The IWMIDSP has been the backbone of several other projects such as global irrigated area mapping, drought monitoring system, wetlands, and knowledge base systems. A discussion on these pathfinder web portals follow.

  4. Data-intensive science gateway for rock physicists and volcanologists.

    NASA Astrophysics Data System (ADS)

    Filgueira, Rosa; Atkinson, Malcom; Bell, Andrew; Main, Ian; Boon, Steve; Meredith, Philp; Kilburn, Christopher

    2014-05-01

    Scientists have always shared data and mathematical models of the phenomena they study. Rock physics and Volcanology, as well as other solid-Earth sciences, have increasingly used Internet communications and computational renditions of their models for this purpose over the last two decades. Here we consider how to organise rock physics and volcanology data to open up opportunities for sharing and comparing both experiment data from experiments, observations and model runs and analytic interpretations of these data. Our hypothesis is that if we facilitate productive information sharing across those communities by using a new science gateway, it will benefit the science. The proposed science gateway should make the first steps for making existing research practices easier and facilitate new research. It will achieve this by supporting three major functions: 1) sharing data from laboratories and observatories, experimental facilities and models; 2) sharing models of rock fracture and methods for analysing experimental data; and 3) supporting recurrent operational tasks, such as data collection and model application in real time. We report initial work in two projects (NERC EFFORT and NERC CREEP-2) and experience with an early web-accessible protytpe called EFFORT gateway, where we are implementing such information sharing services for those projects. 1. Sharing data: In EFFORT gateway, we are working on several facilities for sharing data: *Upload data: We have designed and developed a new adaptive data transfer java tool called FAST (Flexible Automated Streaming Transfer) to upload experimental data and metadata periodically from laboratories to our repository. *Visualisation: As data are deposited in the repository, a visualisation of the accumulated data is made available for display in the Web portal. *Metadata and catalogues: The gateway uses a repository to hold all the data and a catalogue to hold all the corresponding metadata. 2. Sharing models and methods

  5. Van Allen Probes Science Gateway: A Centralized Data Access Point

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Ukhorskiy, A. Y.; Sotirelis, T.; Stephens, G. K.; Kessel, R.; Potter, M.

    2015-12-01

    The Van Allen Probes Science Gateway acts a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the Van Allen Probes Space Weather data to users. Over the past years, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes science and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including, simple time series, data plotted as a function of orbital location, and time versus L-Shell, capability of visualizing data from both probes (A & B) on the same plot. In cooperation with all Van Allen Probes Instrument SOCs, the Science Gateway will soon be able to serve higher level data products (Level 3), and to visualize them via the above mentioned HTML5 interface. Users will also be able to create customized CDF files on the fly.

  6. Globalization, global health, and access to healthcare.

    PubMed

    Collins, Téa

    2003-01-01

    It is now commonly realized that the globalization of the world economy is shaping the patterns of global health, and that associated morbidity and mortality is affecting countries' ability to achieve economic growth. The globalization of public health has important implications for access to essential healthcare. The rise of inequalities among and within countries negatively affects access to healthcare. Poor people use healthcare services less frequently when sick than do the rich. The negative impact of globalization on access to healthcare is particularly well demonstrated in countries of transitional economies. No longer protected by a centralized health sector that provided free universal access to services for everyone, large segments of the populations in the transition period found themselves denied even the most basic medical services. Only countries where regulatory institutions are strong, domestic markets are competitive and social safety nets are in place, have a good chance to enjoy the health benefits of globalization.

  7. The Deep Space Gateway Lightning Mapper (DLM) - Monitoring Global Change and Thunderstorm Processes Through Observations of Earth's High-Latitude Lightning from Cis-Lunar Orbit

    NASA Technical Reports Server (NTRS)

    Lang, Timothy; Blakeslee, R. J.; Cecil, D. J.; Christian, H. J.; Gatlin, P. N.; Goodman, S. J.; Koshak, W. J.; Petersen, W. A.; Quick, M.; Schultz, C. J.; hide

    2018-01-01

    Function: Monitor global change and thunderstorm processes through observations of Earth's high-latitude lightning. This instrument will combine long-lived sampling of individual thunderstorms with long-term observations of lightning at high latitudes: How is global change affecting thunderstorm patterns; How do high-latitude thunderstorms differ from low-latitude? Why is the Gateway the optimal facility for this instrument / research: Expected DSG (Deep Space Gateway) orbits will provide nearly continuous viewing of the Earth's high latitudes (50 degrees latitude and poleward); These regions are not well covered by existing lightning mappers (e.g., Lightning Imaging Sensor / LIS, or Geostationary Lightning Mapper / GLM); Polar, Molniya, Tundra, etc. Earth orbits have significant drawbacks related to continuous coverage and/or stable FOVs (Fields of View).

  8. Front-End/Gateway Software: Availability and Usefulness.

    ERIC Educational Resources Information Center

    Kesselman, Martin

    1985-01-01

    Reviews features of front-end software packages (interface between user and online system)--database selection, search strategy development, saving and downloading, hardware and software requirements, training and documentation, online systems and database accession, and costs--and discusses gateway services (user searches through intermediary…

  9. Towards the impact of eddies on the response of the global ocean circulation to Southern Ocean gateway opening

    NASA Astrophysics Data System (ADS)

    Viebahn, Jan; von der Heydt, Anna S.; Dijkstra, Henk A.

    2014-05-01

    During the past 65 Million (Ma) years, Earth's climate has undergone a major change from warm 'greenhouse' to colder 'icehouse' conditions with extensive ice sheets in the polar regions of both hemispheres. The Eocene-Oligocene (~34 Ma) and Oligocene-Miocene (~23 Ma) boundaries reflect major transitions in Cenozoic global climate change. Proposed mechanisms of these transitions include reorganization of ocean circulation due to critical gateway opening/deepening, changes in atmospheric CO2-concentration, and feedback mechanisms related to land-ice formation. A long-standing hypothesis is that the formation of the Antarctic Circumpolar Current due to opening/deepening of Southern Ocean gateways led to glaciation of the Antarctic continent. However, while this hypothesis remains controversial, its assessment via coupled climate model simulations depends crucially on the spatial resolution in the ocean component. More precisely, only high-resolution modeling of the turbulent ocean circulation is capable of adequately describing reorganizations in the ocean flow field and related changes in turbulent heat transport. In this study, for the first time results of a high-resolution (0.1° horizontally) realistic global ocean model simulation with a closed Drake Passage are presented. Changes in global ocean temperatures, heat transport, and ocean circulation (e.g., Meridional Overturning Circulation and Antarctic Coastal Current) are established by comparison with an open Drake Passage high-resolution reference simulation. Finally, corresponding low-resolution simulations are also analyzed. The results highlight the essential impact of the ocean eddy field in palaeoclimatic change.

  10. Enhancing Return from Lunar Surface Missions via the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Chavers, D. G.; Whitley, R. J.; Percy, T. K.; Needham, D. H.; Polsgrove, T. T.

    2018-02-01

    The Deep Space Gateway (DSG) will facilitate access to and communication with lunar surface assets. With a science airlock, docking port, and refueling capability in an accessible orbit, the DSG will enable high priority science across the lunar surface.

  11. Design of a multimedia gateway for mobile devices

    NASA Astrophysics Data System (ADS)

    Hens, Raf; Goeminne, Nico; Van Hoecke, Sofie; Verdickt, Tom; Bouve, Thomas; Gielen, Frank; Demeester, Piet

    2005-03-01

    Although mobile users are currently offered a lot more capabilities on their mobile devices, they still experience some limitations. They can surf the Internet, read their e-mail and receive MMS messages, but they have limited processing power, storage capacity and bandwidth and are limited in their access to peripherals (e.g. printers). We have designed and implemented a multimedia gateway for mobile devices that reduces these limitations. It gives the mobile devices transparent access to high capacity devices connected to the gateway, which is built around a central, modularly extensible server that can run on any PC or home gateway. It manages two sets of modules: one set offering the actual services and another set handling the IP-based wireless interaction with the client applications on the mobile devices. These modules can be added and removed dynamically, offering new services on the fly. Currently services for storage, printing, domotics and playing music are provided. Others can easily be added later on. This paper discusses the architecture and development, the management of modules, the actual services and their benefits. Besides a proprietary implementation, it also looks into OSGi and how both platforms compare to each other, concerning design, architecture, ease of development, functionality, ...

  12. Van Allen Probes Science Gateway: Single-Point Access to Long-Term Radiation Belt Measurements and Space Weather Nowcasting

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Ukhorskiy, A. Y.; Sotirelis, T.; Stephens, G.

    2017-12-01

    The Science Gateway gives single-point access to over 4.5 years of comprehensive wave and particle measurements from the Van Allen Probes NASA twin-spacecraft mission. The Gateway provides a set of visualization and data analysis tools including: HTML5-based interactive visualization of high-level data products from all instrument teams in the form of: line plots, orbital content plots, dynamical energy spectra, L-shell context plots (including two-spacecraft plotting), FFT spectra of wave data, solar wind and geomagnetic indices data, etc.; download custom multi-instrument CDF data files of selected data products; publication quality plots of digital data; combined orbit predicts for mission planning and coordination including: Van Allen Probes, MMS, THEMIS, Arase (ERG), Cluster, GOES, Geotail, FIREBIRD; magnetic footpoint calculator for coordination with LEO and ground-based assets; real-time computation and processing of empirical magnetic field models - computation of magnetic ephemeris, computation of adiabatic invariants. Van Allen Probes is the first spacecraft mission to provide a nowcast of the radiation environment in the heart of the radiation belts, where the radiation levels are the highest and most dangerous for spacecraft operations. For this purpose, all instruments continuously broadcast a subset of their science data in real time. Van Allen Probes partners with four foreign institutions who operate ground stations that receive the broadcast: Korea (KASI), the Czech republic (CAS), Argentina (CONAE), and Brazil (INPE). The SpWx broadcast is then collected at APL and delivered to the community via the Science Gateway.

  13. UAS-NAS Live Virtual Constructive Distributed Environment (LVC): LVC Gateway, Gateway Toolbox, Gateway Data Logger (GDL), SaaProc Software Design Description

    NASA Technical Reports Server (NTRS)

    Jovic, Srboljub

    2015-01-01

    This document provides the software design description for the two core software components, the LVC Gateway, the LVC Gateway Toolbox, and two participants, the LVC Gateway Data Logger and the SAA Processor (SaaProc).

  14. Remote Asynchronous Message Service Gateway

    NASA Technical Reports Server (NTRS)

    Wang, Shin-Ywan; Burleigh, Scott C.

    2011-01-01

    The Remote Asynchronous Message Service (RAMS) gateway is a special-purpose AMS application node that enables exchange of AMS messages between nodes residing in different AMS "continua," notionally in different geographical locations. JPL s implementation of RAMS gateway functionality is integrated with the ION (Interplanetary Overlay Network) implementation of the DTN (Delay-Tolerant Networking) bundle protocol, and with JPL s implementation of AMS itself. RAMS protocol data units are encapsulated in ION bundles and are forwarded to the neighboring RAMS gateways identified in the source gateway s AMS management information base. Each RAMS gateway has interfaces in two communication environments: the AMS message space it serves, and the RAMS network - the grid or tree of mutually aware RAMS gateways - that enables AMS messages produced in one message space to be forwarded to other message spaces of the same venture. Each gateway opens persistent, private RAMS network communication channels to the RAMS gateways of other message spaces for the same venture, in other continua. The interconnected RAMS gateways use these communication channels to forward message petition assertions and cancellations among themselves. Each RAMS gateway subscribes locally to all subjects that are of interest in any of the linked message spaces. On receiving its copy of a message on any of these subjects, the RAMS gateway node uses the RAMS network to forward the message to every other RAMS gateway whose message space contains at least one node that has subscribed to messages on that subject. On receiving a message via the RAMS network from some other RAMS gateway, the RAMS gateway node forwards the message to all subscribers in its own message space.

  15. Eocene cooling linked to early flow across the Tasmanian Gateway.

    PubMed

    Bijl, Peter K; Bendle, James A P; Bohaty, Steven M; Pross, Jörg; Schouten, Stefan; Tauxe, Lisa; Stickley, Catherine E; McKay, Robert M; Röhl, Ursula; Olney, Matthew; Sluijs, Appy; Escutia, Carlota; Brinkhuis, Henk

    2013-06-11

    The warmest global temperatures of the past 85 million years occurred during a prolonged greenhouse episode known as the Early Eocene Climatic Optimum (52-50 Ma). The Early Eocene Climatic Optimum terminated with a long-term cooling trend that culminated in continental-scale glaciation of Antarctica from 34 Ma onward. Whereas early studies attributed the Eocene transition from greenhouse to icehouse climates to the tectonic opening of Southern Ocean gateways, more recent investigations invoked a dominant role of declining atmospheric greenhouse gas concentrations (e.g., CO2). However, the scarcity of field data has prevented empirical evaluation of these hypotheses. We present marine microfossil and organic geochemical records spanning the early-to-middle Eocene transition from the Wilkes Land Margin, East Antarctica. Dinoflagellate biogeography and sea surface temperature paleothermometry reveal that the earliest throughflow of a westbound Antarctic Counter Current began ~49-50 Ma through a southern opening of the Tasmanian Gateway. This early opening occurs in conjunction with the simultaneous onset of regional surface water and continental cooling (2-4 °C), evidenced by biomarker- and pollen-based paleothermometry. We interpret that the westbound flowing current flow across the Tasmanian Gateway resulted in cooling of Antarctic surface waters and coasts, which was conveyed to global intermediate waters through invigorated deep convection in southern high latitudes. Although atmospheric CO2 forcing alone would provide a more uniform middle Eocene cooling, the opening of the Tasmanian Gateway better explains Southern Ocean surface water and global deep ocean cooling in the apparent absence of (sub-) equatorial cooling.

  16. Eocene cooling linked to early flow across the Tasmanian Gateway

    PubMed Central

    Bijl, Peter K.; Bendle, James A. P.; Bohaty, Steven M.; Pross, Jörg; Schouten, Stefan; Tauxe, Lisa; Stickley, Catherine E.; McKay, Robert M.; Röhl, Ursula; Olney, Matthew; Sluijs, Appy; Escutia, Carlota; Brinkhuis, Henk; Klaus, Adam; Fehr, Annick; Williams, Trevor; Carr, Stephanie A.; Dunbar, Robert B.; Gonzàlez, Jhon J.; Hayden, Travis G.; Iwai, Masao; Jimenez-Espejo, Francisco J.; Katsuki, Kota; Kong, Gee Soo; Nakai, Mutsumi; Passchier, Sandra; Pekar, Stephen F.; Riesselman, Christina; Sakai, Toyosaburo; Shrivastava, Prakash K.; Sugisaki, Saiko; Tuo, Shouting; van de Flierdt, Tina; Welsh, Kevin; Yamane, Masako

    2013-01-01

    The warmest global temperatures of the past 85 million years occurred during a prolonged greenhouse episode known as the Early Eocene Climatic Optimum (52–50 Ma). The Early Eocene Climatic Optimum terminated with a long-term cooling trend that culminated in continental-scale glaciation of Antarctica from 34 Ma onward. Whereas early studies attributed the Eocene transition from greenhouse to icehouse climates to the tectonic opening of Southern Ocean gateways, more recent investigations invoked a dominant role of declining atmospheric greenhouse gas concentrations (e.g., CO2). However, the scarcity of field data has prevented empirical evaluation of these hypotheses. We present marine microfossil and organic geochemical records spanning the early-to-middle Eocene transition from the Wilkes Land Margin, East Antarctica. Dinoflagellate biogeography and sea surface temperature paleothermometry reveal that the earliest throughflow of a westbound Antarctic Counter Current began ∼49–50 Ma through a southern opening of the Tasmanian Gateway. This early opening occurs in conjunction with the simultaneous onset of regional surface water and continental cooling (2–4 °C), evidenced by biomarker- and pollen-based paleothermometry. We interpret that the westbound flowing current flow across the Tasmanian Gateway resulted in cooling of Antarctic surface waters and coasts, which was conveyed to global intermediate waters through invigorated deep convection in southern high latitudes. Although atmospheric CO2 forcing alone would provide a more uniform middle Eocene cooling, the opening of the Tasmanian Gateway better explains Southern Ocean surface water and global deep ocean cooling in the apparent absence of (sub-) equatorial cooling. PMID:23720311

  17. Research of Ad Hoc Networks Access Algorithm

    NASA Astrophysics Data System (ADS)

    Xiang, Ma

    With the continuous development of mobile communication technology, Ad Hoc access network has become a hot research, Ad Hoc access network nodes can be used to expand capacity of multi-hop communication range of mobile communication system, even business adjacent to the community, improve edge data rates. When the ad hoc network is the access network of the internet, the gateway discovery protocol is very important to choose the most appropriate gateway to guarantee the connectivity between ad hoc network and IP based fixed networks. The paper proposes a QoS gateway discovery protocol which uses the time delay and stable route to the gateway selection conditions. And according to the gateway discovery protocol, it also proposes a fast handover scheme which can decrease the handover time and improve the handover efficiency.

  18. Science Gateways, Scientific Workflows and Open Community Software

    NASA Astrophysics Data System (ADS)

    Pierce, M. E.; Marru, S.

    2014-12-01

    Science gateways and scientific workflows occupy different ends of the spectrum of user-focused cyberinfrastructure. Gateways, sometimes called science portals, provide a way for enabling large numbers of users to take advantage of advanced computing resources (supercomputers, advanced storage systems, science clouds) by providing Web and desktop interfaces and supporting services. Scientific workflows, at the other end of the spectrum, support advanced usage of cyberinfrastructure that enable "power users" to undertake computational experiments that are not easily done through the usual mechanisms (managing simulations across multiple sites, for example). Despite these different target communities, gateways and workflows share many similarities and can potentially be accommodated by the same software system. For example, pipelines to process InSAR imagery sets or to datamine GPS time series data are workflows. The results and the ability to make downstream products may be made available through a gateway, and power users may want to provide their own custom pipelines. In this abstract, we discuss our efforts to build an open source software system, Apache Airavata, that can accommodate both gateway and workflow use cases. Our approach is general, and we have applied the software to problems in a number of scientific domains. In this talk, we discuss our applications to usage scenarios specific to earth science, focusing on earthquake physics examples drawn from the QuakSim.org and GeoGateway.org efforts. We also examine the role of the Apache Software Foundation's open community model as a way to build up common commmunity codes that do not depend upon a single "owner" to sustain. Pushing beyond open source software, we also see the need to provide gateways and workflow systems as cloud services. These services centralize operations, provide well-defined programming interfaces, scale elastically, and have global-scale fault tolerance. We discuss our work providing

  19. Neutron Science TeraGrid Gateway

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lynch, Vickie E; Chen, Meili; Cobb, John W

    The unique contributions of the Neutron Science TeraGrid Gateway (NSTG) are the connection of national user facility instrument data sources to the integrated cyberinfrastructure of the National Science FoundationTeraGrid and the development of a neutron science gateway that allows neutron scientists to use TeraGrid resources to analyze their data, including comparison of experiment with simulation. The NSTG is working in close collaboration with the Spallation Neutron Source (SNS) at Oak Ridge as their principal facility partner. The SNS is a next-generation neutron source. It has completed construction at a cost of $1.4 billion and is ramping up operations. The SNSmore » will provide an order of magnitude greater flux than any previous facility in the world and will be available to all of the nation's scientists, independent of funding source, on a peer-reviewed merit basis. With this new capability, the neutron science community is facing orders of magnitude larger data sets and is at a critical point for data analysis and simulation. There is a recognized need for new ways to manage and analyze data to optimize both beam time and scientific output. The TeraGrid is providing new capabilities in the gateway for simulations using McStas and a fitting service on distributed TeraGrid resources to improved turnaround. NSTG staff are also exploring replicating experimental data in archival storage. As part of the SNS partnership, the NSTG provides access to gateway support, cyberinfrastructure outreach, community development, and user support for the neutron science community. This community includes not only SNS staff and users but extends to all the major worldwide neutron scattering centers.« less

  20. Remote Sensing Information Gateway (RSIG3D) Fact Sheet

    EPA Pesticide Factsheets

    The Remote Sensing Information Gateway-3D (RSIG3D) is a free and downloadable application that provides easy and secure access to petabytes (millions of gigabytes) of atmospheric data that can be used to study complex air quality issues.

  1. Environmental Dataset Gateway (EDG) Search Widget

    EPA Pesticide Factsheets

    Use the Environmental Dataset Gateway (EDG) to find and access EPA's environmental resources. Many options are available for easily reusing EDG content in other other applications. This allows individuals to provide direct access to EPA's metadata outside the EDG interface. The EDG Search Widget makes it possible to search the EDG from another web page or application. The search widget can be included on your website by simply inserting one or two lines of code. Users can type a search term or lucene search query in the search field and retrieve a pop-up list of records that match that search.

  2. Detection and response to unauthorized access to a communication device

    DOEpatents

    Smith, Rhett; Gordon, Colin

    2015-09-08

    A communication gateway consistent with the present disclosure may detect unauthorized physical or electronic access and implement security actions in response thereto. A communication gateway may provide a communication path to an intelligent electronic device (IED) using an IED communications port configured to communicate with the IED. The communication gateway may include a physical intrusion detection port and a network port. The communication gateway may further include control logic configured to evaluate physical intrusion detection signal. The control logic may be configured to determine that the physical intrusion detection signal is indicative of an attempt to obtain unauthorized access to one of the communication gateway, the IED, and a device in communication with the gateway; and take a security action based upon the determination that the indication is indicative of the attempt to gain unauthorized access.

  3. The Vocational Baccalaureate: A Gateway to Higher Education?

    ERIC Educational Resources Information Center

    Gendron, Benedicte

    2009-01-01

    Access to the baccalaureate and higher education in France has become more democratic. The introduction of the vocational baccalaureate has been part of this process, but remains a modest step forward given the very low take-up of vocational baccalaureate courses. If vocational education pathways in France are to become true gateways to higher…

  4. Early experiences in developing and managing the neuroscience gateway.

    PubMed

    Sivagnanam, Subhashini; Majumdar, Amit; Yoshimoto, Kenneth; Astakhov, Vadim; Bandrowski, Anita; Martone, MaryAnn; Carnevale, Nicholas T

    2015-02-01

    The last few decades have seen the emergence of computational neuroscience as a mature field where researchers are interested in modeling complex and large neuronal systems and require access to high performance computing machines and associated cyber infrastructure to manage computational workflow and data. The neuronal simulation tools, used in this research field, are also implemented for parallel computers and suitable for high performance computing machines. But using these tools on complex high performance computing machines remains a challenge because of issues with acquiring computer time on these machines located at national supercomputer centers, dealing with complex user interface of these machines, dealing with data management and retrieval. The Neuroscience Gateway is being developed to alleviate and/or hide these barriers to entry for computational neuroscientists. It hides or eliminates, from the point of view of the users, all the administrative and technical barriers and makes parallel neuronal simulation tools easily available and accessible on complex high performance computing machines. It handles the running of jobs and data management and retrieval. This paper shares the early experiences in bringing up this gateway and describes the software architecture it is based on, how it is implemented, and how users can use this for computational neuroscience research using high performance computing at the back end. We also look at parallel scaling of some publicly available neuronal models and analyze the recent usage data of the neuroscience gateway.

  5. Early experiences in developing and managing the neuroscience gateway

    PubMed Central

    Sivagnanam, Subhashini; Majumdar, Amit; Yoshimoto, Kenneth; Astakhov, Vadim; Bandrowski, Anita; Martone, MaryAnn; Carnevale, Nicholas. T.

    2015-01-01

    SUMMARY The last few decades have seen the emergence of computational neuroscience as a mature field where researchers are interested in modeling complex and large neuronal systems and require access to high performance computing machines and associated cyber infrastructure to manage computational workflow and data. The neuronal simulation tools, used in this research field, are also implemented for parallel computers and suitable for high performance computing machines. But using these tools on complex high performance computing machines remains a challenge because of issues with acquiring computer time on these machines located at national supercomputer centers, dealing with complex user interface of these machines, dealing with data management and retrieval. The Neuroscience Gateway is being developed to alleviate and/or hide these barriers to entry for computational neuroscientists. It hides or eliminates, from the point of view of the users, all the administrative and technical barriers and makes parallel neuronal simulation tools easily available and accessible on complex high performance computing machines. It handles the running of jobs and data management and retrieval. This paper shares the early experiences in bringing up this gateway and describes the software architecture it is based on, how it is implemented, and how users can use this for computational neuroscience research using high performance computing at the back end. We also look at parallel scaling of some publicly available neuronal models and analyze the recent usage data of the neuroscience gateway. PMID:26523124

  6. Gateway National Recreation Area, Jamaica Bay Unit alternative transportation feasibility study

    DOT National Transportation Integrated Search

    2013-07-31

    The National Park Service Gateway National Recreation Area (GATE) was created to provide convenient access to outdoor recreation in the National Park System for residents and visitors to the New York City (NYC) area. The Volpe Center completed a numb...

  7. Open access: changing global science publishing.

    PubMed

    Gasparyan, Armen Yuri; Ayvazyan, Lilit; Kitas, George D

    2013-08-01

    The article reflects on open access as a strategy of changing the quality of science communication globally. Successful examples of open-access journals are presented to highlight implications of archiving in open digital repositories for the quality and citability of research output. Advantages and downsides of gold, green, and hybrid models of open access operating in diverse scientific environments are described. It is assumed that open access is a global trend which influences the workflow in scholarly journals, changing their quality, credibility, and indexability.

  8. Earth-from-Luna Limb Imager (ELLI) for Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Gorkavyi, N.; DeLand, M.

    2018-02-01

    The new type of limb imager with a high-frequency imaging proposed for Deep Space Gateway. Each day this CubeSat' scale imager will generate the global 3D model of the aerosol component of the Earth's atmosphere and Polar Mesospheric Clouds.

  9. Communications Relay and Human-Assisted Sample Return from the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Cichan, T.; Hopkins, J. B.; Bierhaus, B.; Murrow, D. W.

    2018-02-01

    The Deep Space Gateway can enable or enhance exploration of the lunar surface through two capabilities: 1. communications relay, opening up access to the lunar farside, and 2. sample return, enhancing the ability to return large sample masses.

  10. Gateways to State and Local Government Information on the Internet.

    ERIC Educational Resources Information Center

    Maxwell, Bruce

    1995-01-01

    Describes some of the most useful gateways that can be used to access state and local government information on the Internet, including StateSearch, Council of State Governments, U.S. House of Representatives Internet Law Library, LC MARVEL, CityNet, California Home Page, and New York State Library Gopher. (LRW)

  11. Accessing Electronic Journals.

    ERIC Educational Resources Information Center

    McKay, Sharon Cline

    1999-01-01

    Discusses issues librarians need to consider when providing access to electronic journals. Topics include gateways; index and abstract services; validation and pay-per-view; title selection; integration with OPACs (online public access catalogs)or Web sites; paper availability; ownership versus access; usage restrictions; and services offered…

  12. Network flexibility of the IRIDIUM (R) Global Mobile Satellite System

    NASA Technical Reports Server (NTRS)

    Hutcheson, Jonathan; Laurin, Mala

    1995-01-01

    The IRIDIUM system is a global personal communications system supported by a constellation of 66 low earth orbit (LEO) satellites and a collection of earth-based 'gateway' switching installations. Like traditional wireless cellular systems, coverage is achieved by a grid of cells in which bandwidth is reused for spectral efficiency. Unlike any cellular system ever built, the moving cells can be shared by multiple switching facilities. Noteworthy features of the IRIDIUM system include inter-satellite links, a GSM-based telephony architecture, and a geographically controlled system access process. These features, working in concert, permit flexible and reliable administration of the worldwide service area by gateway operators. This paper will explore this unique concept.

  13. High-Performance Satellite/Terrestrial-Network Gateway

    NASA Technical Reports Server (NTRS)

    Beering, David R.

    2005-01-01

    A gateway has been developed to enable digital communication between (1) the high-rate receiving equipment at NASA's White Sands complex and (2) a standard terrestrial digital communication network at data rates up to 622 Mb/s. The design of this gateway can also be adapted for use in commercial Earth/satellite and digital communication networks, and in terrestrial digital communication networks that include wireless subnetworks. Gateway as used here signifies an electronic circuit that serves as an interface between two electronic communication networks so that a computer (or other terminal) on one network can communicate with a terminal on the other network. The connection between this gateway and the high-rate receiving equipment is made via a synchronous serial data interface at the emitter-coupled-logic (ECL) level. The connection between this gateway and a standard asynchronous transfer mode (ATM) terrestrial communication network is made via a standard user network interface with a synchronous optical network (SONET) connector. The gateway contains circuitry that performs the conversion between the ECL and SONET interfaces. The data rate of the SONET interface can be either 155.52 or 622.08 Mb/s. The gateway derives its clock signal from a satellite modem in the high-rate receiving equipment and, hence, is agile in the sense that it adapts to the data rate of the serial interface.

  14. Gateway to the Future

    ERIC Educational Resources Information Center

    DiJulio, Betsy

    2012-01-01

    "Gateway to the Future" pairs a painting of a gateway constructed from children's building blocks with an ink drawing of a personal symbol on a collaged background. The main objective of this lesson is to create a metaphoric artwork about moving from the present through a symbolic portal to the future. So, space--foreground, middle ground, and…

  15. EAC and the Development of National and European Gateways to Archives

    ERIC Educational Resources Information Center

    Ottosson, Per-Gunnar

    2005-01-01

    In the development of gateways to archives there are two different approaches, one focusing on the descriptions of the material and the other on the creators. Search and retrieval with precision and quality require controlled access points and name authority control. National registries of private archives have a long tradition in implementing the…

  16. Deep Space Gateway Science Opportunities

    NASA Astrophysics Data System (ADS)

    Quincy, C. D.; Charles, J. B.; Hamill, D. L.; Sun, S. C.

    2018-02-01

    Life sciences see the Deep Space Gateway as an opportunity to investigate biological organisms in a unique environment that cannot be replicated in Earth-based labs or on LEO platforms. The needed capabilities must be built into the Gateway facility.

  17. A Standard-Based and Context-Aware Architecture for Personal Healthcare Smart Gateways.

    PubMed

    Santos, Danilo F S; Gorgônio, Kyller C; Perkusich, Angelo; Almeida, Hyggo O

    2016-10-01

    The rising availability of Personal Health Devices (PHDs) capable of Personal Network Area (PAN) communication and the desire of keeping a high quality of life are the ingredients of the Connected Health vision. In parallel, a growing number of personal and portable devices, like smartphones and tablet computers, are becoming capable of taking the role of health gateway, that is, a data collector for the sensor PHDs. However, as the number of PHDs increase, the number of other peripherals connected in PAN also increases. Therefore, PHDs are now competing for medium access with other devices, decreasing the Quality of Service (QoS) of health applications in the PAN. In this article we present a reference architecture to prioritize PHD connections based on their state and requirements, creating a healthcare Smart Gateway. Healthcare context information is extracted by observing the traffic through the gateway. A standard-based approach was used to identify health traffic based on ISO/IEEE 11073 family of standards. A reference implementation was developed showing the relevance of the problem and how the proposed architecture can assist in the prioritization. The reference Smart Gateway solution was integrated with a Connected Health System for the Internet of Things, validating its use in a real case scenario.

  18. Lyceum: A Multi-Protocol Digital Library Gateway

    NASA Technical Reports Server (NTRS)

    Maa, Ming-Hokng; Nelson, Michael L.; Esler, Sandra L.

    1997-01-01

    Lyceum is a prototype scalable query gateway that provides a logically central interface to multi-protocol and physically distributed, digital libraries of scientific and technical information. Lyceum processes queries to multiple syntactically distinct search engines used by various distributed information servers from a single logically central interface without modification of the remote search engines. A working prototype (http://www.larc.nasa.gov/lyceum/) demonstrates the capabilities, potentials, and advantages of this type of meta-search engine by providing access to over 50 servers covering over 20 disciplines.

  19. Social class culture cycles: how three gateway contexts shape selves and fuel inequality.

    PubMed

    Stephens, Nicole M; Markus, Hazel Rose; Phillips, L Taylor

    2014-01-01

    America's unprecedented levels of inequality have far-reaching negative consequences for society as a whole. Although differential access to resources contributes to inequality, the current review illuminates how ongoing participation in different social class contexts also gives rise to culture-specific selves and patterns of thinking, feeling, and acting. We integrate a growing body of interdisciplinary research to reveal how social class culture cycles operate over the course of the lifespan and through critical gateway contexts, including homes, schools, and workplaces. We first document how each of these contexts socializes social class cultural differences. Then, we demonstrate how these gateway institutions, which could provide access to upward social mobility, are structured according to middle-class ways of being a self and thus can fuel and perpetuate inequality. We conclude with a discussion of intervention opportunities that can reduce inequality by taking into account the contextual responsiveness of the self.

  20. Integrating QoS and security functions in an IP-VPN gateway

    NASA Astrophysics Data System (ADS)

    Fan, Kuo-Pao; Chang, Shu-Hsin; Lin, Kuan-Ming; Pen, Mau-Jy

    2001-10-01

    IP-based Virtual Private Network becomes more and more popular. It can not only reduce the enterprise communication cost but also increase the revenue of the service provider. The common IP-VPN application types include Intranet VPN, Extranet VPN, and remote access VPN. For the large IP-VPN market, some vendors develop dedicated IP-VPN devices; while some vendors add the VPN functions into their existing network equipment such as router, access gateway, etc. The functions in the IP-VPN device include security, QoS, and management. The common security functions supported are IPSec (IP Security), IKE (Internet Key Exchange), and Firewall. The QoS functions include bandwidth control and packet scheduling. In the management component, policy-based network management is under standardization in IETF. In this paper, we discuss issues on how to integrate the QoS and security functions in an IP-VPN Gateway. We propose three approaches to do this. They are (1) perform Qos first (2) perform IPSec first and (3) reserve fixed bandwidth for IPSec. We also compare the advantages and disadvantages of the three proposed approaches.

  1. Community Colleges as Gateways and Gatekeepers: Moving beyond the Access "Saga" toward Outcome Equity

    ERIC Educational Resources Information Center

    Dowd, Alicia C.

    2007-01-01

    Community colleges are essential--though often overlooked--institutions of higher education. In this essay, Alicia C. Dowd draws attention to the challenges facing community colleges as they seek to balance their roles as both gateways and gatekeepers with their multiple missions, which include meeting the diverse needs of students at the…

  2. A RESTful image gateway for multiple medical image repositories.

    PubMed

    Valente, Frederico; Viana-Ferreira, Carlos; Costa, Carlos; Oliveira, José Luis

    2012-05-01

    Mobile technologies are increasingly important components in telemedicine systems and are becoming powerful decision support tools. Universal access to data may already be achieved by resorting to the latest generation of tablet devices and smartphones. However, the protocols employed for communicating with image repositories are not suited to exchange data with mobile devices. In this paper, we present an extensible approach to solving the problem of querying and delivering data in a format that is suitable for the bandwidth and graphic capacities of mobile devices. We describe a three-tiered component-based gateway that acts as an intermediary between medical applications and a number of Picture Archiving and Communication Systems (PACS). The interface with the gateway is accomplished using Hypertext Transfer Protocol (HTTP) requests following a Representational State Transfer (REST) methodology, which relieves developers from dealing with complex medical imaging protocols and allows the processing of data on the server side.

  3. Enabling Global Lunar Sample Return and Life-Detection Studies Using a Deep-Space Gateway

    NASA Astrophysics Data System (ADS)

    Cohen, B. A.; Eigenbrode, J. A.; Young, K. E.; Bleacher, J. E.; Trainer, M. E.

    2018-02-01

    The Deep Space Gateway could uniquely enable a lunar robotic sampling campaign that would provide incredible science return as well as feed forward to Mars and Europa by testing instrument sterility and ability to distinguish biogenic signals.

  4. Gateway to Learning: Empowering Individuals?

    ERIC Educational Resources Information Center

    Salveson, Paul; And Others

    Gateway to Learning is a British government initiative that aims to provide new guidance opportunities for adults through a voucher system. In Leeds (England), Gateway to Learning services are targeted toward the following groups: long-term unemployed; short-term unemployed; people facing redundancy; and Asian communities. The program's…

  5. Implementing Patient Access to Electronic Health Records Under HIPAA: Lessons Learned

    PubMed Central

    Wang, Tiffany; Pizziferri, Lisa; Volk, Lynn A; Mikels, Debra A; Grant, Karen G; Wald, Jonathan S; Bates, David W

    2004-01-01

    In 2001, the Institute of Medicine (IOM) and the Health Insurance Portability and Accountability Act (HIPAA) emphasized the need for patients to have greater control over their health information. We describe a Boston healthcare system's approach to providing patients access to their electronic health records (EHRs) via Patient Gateway, a secure, Web-based portal. Implemented in 19 clinic sites to date, Patient Gateway allows patients to access information from their medical charts via the Internet in a secure manner. Since 2002, over 19,000 patients have enrolled in Patient Gateway, more than 125,000 patients have logged into the system, and over 37,000 messages have been sent by patients to their practices. There have been no major security concerns. By providing access to EHR data, secure systems like Patient Gateway allow patients a greater role in their healthcare process, as envisioned by the IOM and HIPAA. PMID:18066391

  6. Gateway design specification for fiber optic local area networks

    NASA Technical Reports Server (NTRS)

    1985-01-01

    This is a Design Specification for a gateway to interconnect fiber optic local area networks (LAN's). The internetworking protocols for a gateway device that will interconnect multiple local area networks are defined. This specification serves as input for preparation of detailed design specifications for the hardware and software of a gateway device. General characteristics to be incorporated in the gateway such as node address mapping, packet fragmentation, and gateway routing features are described.

  7. NASA's Earth Science Gateway: A Platform for Interoperable Services in Support of the GEOSS Architecture

    NASA Astrophysics Data System (ADS)

    Alameh, N.; Bambacus, M.; Cole, M.

    2006-12-01

    Nasa's Earth Science as well as interdisciplinary research and applications activities require access to earth observations, analytical models and specialized tools and services, from diverse distributed sources. Interoperability and open standards for geospatial data access and processing greatly facilitate such access among the information and processing compo¬nents related to space¬craft, airborne, and in situ sensors; predictive models; and decision support tools. To support this mission, NASA's Geosciences Interoperability Office (GIO) has been developing the Earth Science Gateway (ESG; online at http://esg.gsfc.nasa.gov) by adapting and deploying a standards-based commercial product. Thanks to extensive use of open standards, ESG can tap into a wide array of online data services, serve a variety of audiences and purposes, and adapt to technology and business changes. Most importantly, the use of open standards allow ESG to function as a platform within a larger context of distributed geoscience processing, such as the Global Earth Observing System of Systems (GEOSS). ESG shares the goals of GEOSS to ensure that observations and products shared by users will be accessible, comparable, and understandable by relying on common standards and adaptation to user needs. By maximizing interoperability, modularity, extensibility and scalability, ESG's architecture fully supports the stated goals of GEOSS. As such, ESG's role extends beyond that of a gateway to NASA science data to become a shared platform that can be leveraged by GEOSS via: A modular and extensible architecture Consensus and community-based standards (e.g. ISO and OGC standards) A variety of clients and visualization techniques, including WorldWind and Google Earth A variety of services (including catalogs) with standard interfaces Data integration and interoperability Mechanisms for user involvement and collaboration Mechanisms for supporting interdisciplinary and domain-specific applications ESG

  8. Working research codes into fluid dynamics education: a science gateway approach

    NASA Astrophysics Data System (ADS)

    Mason, Lachlan; Hetherington, James; O'Reilly, Martin; Yong, May; Jersakova, Radka; Grieve, Stuart; Perez-Suarez, David; Klapaukh, Roman; Craster, Richard V.; Matar, Omar K.

    2017-11-01

    Research codes are effective for illustrating complex concepts in educational fluid dynamics courses, compared to textbook examples, an interactive three-dimensional visualisation can bring a problem to life! Various barriers, however, prevent the adoption of research codes in teaching: codes are typically created for highly-specific `once-off' calculations and, as such, have no user interface and a steep learning curve. Moreover, a code may require access to high-performance computing resources that are not readily available in the classroom. This project allows academics to rapidly work research codes into their teaching via a minimalist `science gateway' framework. The gateway is a simple, yet flexible, web interface allowing students to construct and run simulations, as well as view and share their output. Behind the scenes, the common operations of job configuration, submission, monitoring and post-processing are customisable at the level of shell scripting. In this talk, we demonstrate the creation of an example teaching gateway connected to the Code BLUE fluid dynamics software. Student simulations can be run via a third-party cloud computing provider or a local high-performance cluster. EPSRC, UK, MEMPHIS program Grant (EP/K003976/1), RAEng Research Chair (OKM).

  9. The impact of Southern Ocean gateways on the Cenozoic climate evolution

    NASA Astrophysics Data System (ADS)

    von der Heydt, Anna; Viebahn, Jan; Dijkstra, Henk

    2016-04-01

    During the Cenozoic period, which covers the last 65 Million (Ma) years, Earth's climate has undergone a major long-term transition from warm "greenhouse" to colder "icehouse" conditions with extensive ice sheets in the polar regions of both hemispheres. On the very long term the gradual cooling may be seen as response to the overall slowly decreasing atmospheric CO2-concentration due to weathering processes in the Earth System, however, continental geometry has changed considerably over this period and the long-term gradual trend was interrupted, by several rapid transitions as well as periods where temperature and greenhouse gas concentrations seem to be decoupled. The Eocene-Oligocene boundary (˜34 Ma, E/O) and mid-Miocene climatic transition (˜13 Ma, MCT) reflect major phases of Antarctic ice sheet build-up and global climate cooling, while Northern Hemisphere ice sheets developed much later, most likely at the Pliocene-Pleistocene transition (˜2.7Ma). Thresholds in atmospheric CO2-concentration together with feedback mechanisms related to land ice formation are now among the favoured mechanisms of these climatic transitions, while the long-proposed ocean circulation changes caused by opening of tectonic gateways seem to play a less direct role. The opening of the Southern Ocean gateways, notably the Drake Passage and the Tasman Gateway as well as the northward movement of Australia over this long time period, however, has eventually led to the development of today's strongest ocean current, the Antarctic Circumpolar Current (ACC), playing a major role in the transport properties of the global ocean circulation. The overall state of the global ocean circulation, therefore, preconditions the climate system to dramatic events such as major ice sheet formation. Here, we present results of a state-of-the art global climate model (CESM) under various continental configurations: (i) present day geometry, (ii) present day geometry with a closed Drake Passage and

  10. The federal health record gateway.

    PubMed

    Porter, Dennis

    2010-01-01

    The federal government can make federally held health data available to every American through a single, secure, recurring instance based portal on the emerging Nationwide Health Information Network (NHIN). The Federal Health Record Gateway (FHR Gateway) supports the President's initiatives for patient-centered health by enhancing transparency of government-held clinical and health claims data.

  11. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... must be identified by a unique IP address or domain name. (b) Authentication and validation. The CMS... alert gateway if a validation fails. (c) Security. The CMS provider gateway must support standardized IP... CMSP Name Unique identification of CMSP. CMSP gateway Address IP address or Domain Name Alternate IP...

  12. The Climate-G Portal: a Grid Enabled Scientifc Gateway for Climate Change

    NASA Astrophysics Data System (ADS)

    Fiore, Sandro; Negro, Alessandro; Aloisio, Giovanni

    2010-05-01

    Grid portals are web gateways aiming at concealing the underlying infrastructure through a pervasive, transparent, user-friendly, ubiquitous and seamless access to heterogeneous and geographical spread resources (i.e. storage, computational facilities, services, sensors, network, databases). Definitively they provide an enhanced problem-solving environment able to deal with modern, large scale scientific and engineering problems. Scientific gateways are able to introduce a revolution in the way scientists and researchers organize and carry out their activities. Access to distributed resources, complex workflow capabilities, and community-oriented functionalities are just some of the features that can be provided by such a web-based environment. In the context of the EGEE NA4 Earth Science Cluster, Climate-G is a distributed testbed focusing on climate change research topics. The Euro-Mediterranean Center for Climate Change (CMCC) is actively participating in the testbed providing the scientific gateway (Climate-G Portal) to access to the entire infrastructure. The Climate-G Portal has to face important and critical challenges as well as has to satisfy and address key requirements. In the following, the most relevant ones are presented and discussed. Transparency: the portal has to provide a transparent access to the underlying infrastructure preventing users from dealing with low level details and the complexity of a distributed grid environment. Security: users must be authenticated and authorized on the portal to access and exploit portal functionalities. A wide set of roles is needed to clearly assign the proper one to each user. The access to the computational grid must be completely secured, since the target infrastructure to run jobs is a production grid environment. A security infrastructure (based on X509v3 digital certificates) is strongly needed. Pervasivity and ubiquity: the access to the system must be pervasive and ubiquitous. This is easily true due

  13. Building a Gateway for the CD-ROM Network: A Step toward the Virtual Library with the Virtual Microsystems V-Server.

    ERIC Educational Resources Information Center

    Sylvia, Margaret

    1993-01-01

    Describes one college library's experience with a gateway for dial-in access to its CD-ROM network to increase access to automated index searching for students off-campus. Hardware and software choices are discussed in terms of access, reliability, affordability, and ease of use. Installation problems are discussed, and an appendix lists product…

  14. GLOBAL EARTH OBSERVATION SYSTEM OF SYSTEMS (GEOSS) REMOTE SENSING INFORMATION GATEWAY DEMONSTRATION

    EPA Science Inventory

    How do forest fires in a state or country impact the health of residents, living thousands of miles away? How do we better track the effects of heavy urban rain runoff into nearby lakes to provide unprecedented access to and use of global Earth observation information to track, ...

  15. High-performance parallel interface to synchronous optical network gateway

    DOEpatents

    St. John, Wallace B.; DuBois, David H.

    1996-01-01

    A system of sending and receiving gateways interconnects high speed data interfaces, e.g., HIPPI interfaces, through fiber optic links, e.g., a SONET network. An electronic stripe distributor distributes bytes of data from a first interface at the sending gateway onto parallel fiber optics of the fiber optic link to form transmitted data. An electronic stripe collector receives the transmitted data on the parallel fiber optics and reforms the data into a format effective for input to a second interface at the receiving gateway. Preferably, an error correcting syndrome is constructed at the sending gateway and sent with a data frame so that transmission errors can be detected and corrected in a real-time basis. Since the high speed data interface operates faster than any of the fiber optic links the transmission rate must be adapted to match the available number of fiber optic links so the sending and receiving gateways monitor the availability of fiber links and adjust the data throughput accordingly. In another aspect, the receiving gateway must have sufficient available buffer capacity to accept an incoming data frame. A credit-based flow control system provides for continuously updating the sending gateway on the available buffer capacity at the receiving gateway.

  16. High-performance parallel interface to synchronous optical network gateway

    DOEpatents

    St. John, W.B.; DuBois, D.H.

    1996-12-03

    Disclosed is a system of sending and receiving gateways interconnects high speed data interfaces, e.g., HIPPI interfaces, through fiber optic links, e.g., a SONET network. An electronic stripe distributor distributes bytes of data from a first interface at the sending gateway onto parallel fiber optics of the fiber optic link to form transmitted data. An electronic stripe collector receives the transmitted data on the parallel fiber optics and reforms the data into a format effective for input to a second interface at the receiving gateway. Preferably, an error correcting syndrome is constructed at the sending gateway and sent with a data frame so that transmission errors can be detected and corrected in a real-time basis. Since the high speed data interface operates faster than any of the fiber optic links the transmission rate must be adapted to match the available number of fiber optic links so the sending and receiving gateways monitor the availability of fiber links and adjust the data throughput accordingly. In another aspect, the receiving gateway must have sufficient available buffer capacity to accept an incoming data frame. A credit-based flow control system provides for continuously updating the sending gateway on the available buffer capacity at the receiving gateway. 7 figs.

  17. Role of Marine Gateways in the Paleoceanography of the Miocene Mediterranean Sea; A Model Study

    NASA Astrophysics Data System (ADS)

    de la Vara, A.; Meijer, P. T.

    2015-12-01

    During the Miocene, due to the convergence of the African plate and the Eurasian plate, the Mediterranean region was subject to profound paleogeographic changes. The evolving coastline and bathymetry of the Mediterranean Sea and, in particular, the opening and closure of the marine connections between the Mediterranean and the outside oceans, triggered important changes in Mediterranean circulation and, indirectly, also affected the global-scale ocean circulation. Until about the Middle Miocene the proto-Mediterranean Sea was open to the Indo-Pacific Ocean through the so-called Indian Gateway. Although the exact age of closure of this gateway is still debated, it is accepted that it substantially affected the paleoceanography of the Mediterranean Sea. Later in time, during the Late Miocene, the Mediterranean was only connected to the Atlantic Ocean but by two marine corridors: the Betic and Rifian corridors. Closure of these narrow passages resulted in the Messinian Salinity Crisis, during which a sequence of evaporites was deposited throughout the Mediterranean basin. In this work we use a regional-scale ocean general circulation model (the Princeton Ocean Model) to gain insight into the role of the evolving gateways. The analysis focuses on large-scale (overturning) circulation, patterns of exchange in the gateways and properties of the Mediterranean water. By comparing our model results to geological data we are able to propose new scenarios or rule out previously proposed ones, and determine the conditions evidenced by the geological observations. More specifically we investigate two different topics: (i) the effects of shoaling and closure of the Indian Gateway and (ii) the functioning of the Late Miocene double gateway to the Atlantic.

  18. The VERCE Science Gateway: Enabling User Friendly HPC Seismic Wave Simulations.

    NASA Astrophysics Data System (ADS)

    Casarotti, E.; Spinuso, A.; Matser, J.; Leong, S. H.; Magnoni, F.; Krause, A.; Garcia, C. R.; Muraleedharan, V.; Krischer, L.; Anthes, C.

    2014-12-01

    The EU-funded project VERCE (Virtual Earthquake and seismology Research Community in Europe) aims to deploy technologies which satisfy the HPC and data-intensive requirements of modern seismology.As a result of VERCE official collaboration with the EU project SCI-BUS, access to computational resources, like local clusters and international infrastructures (EGI and PRACE), is made homogeneous and integrated within a dedicated science gateway based on the gUSE framework. In this presentation we give a detailed overview on the progress achieved with the developments of the VERCE Science Gateway, according to a use-case driven implementation strategy. More specifically, we show how the computational technologies and data services have been integrated within a tool for Seismic Forward Modelling, whose objective is to offer the possibility to performsimulations of seismic waves as a service to the seismological community.We will introduce the interactive components of the OGC map based web interface and how it supports the user with setting up the simulation. We will go through the selection of input data, which are either fetched from federated seismological web services, adopting community standards, or provided by the users themselves by accessing their own document data store. The HPC scientific codes can be selected from a number of waveform simulators, currently available to the seismological community as batch tools or with limited configuration capabilities in their interactive online versions.The results will be staged out via a secure GridFTP transfer to a VERCE data layer managed by iRODS. The provenance information of the simulation will be automatically cataloged by the data layer via NoSQL techonologies.Finally, we will show the example of how the visualisation output of the gateway could be enhanced by the connection with immersive projection technology at the Virtual Reality and Visualisation Centre of Leibniz Supercomputing Centre (LRZ).

  19. Gateways Revitalization Strategy

    EPA Pesticide Factsheets

    Lancaster County, PA, created the Gateway plan to reconnect various areas of the community, revitalize the economic base, improve and build on infrastructure and public/private partnerships, and retain current residents.

  20. The Effectiveness of Gateway Communications in Anti-Marijuana Campaigns

    PubMed Central

    YZER, MARCO C.; CAPPELLA, JOSEPH N.; FISHBEIN, MARTIN; HORNIK, ROBERT; AHERN, R. KIRKLAND

    2014-01-01

    Successful anti-marijuana messages can be hypothesized to have two types of effects, namely persuasion effects, that is, a change in people’s beliefs about using marijuana, and priming effects, that is, a strengthened correlation between beliefs and associated variables such as attitude and intention. This study examined different sets of anti-drug advertisements for persuasion and priming effects. The ads targeted the belief that marijuana is a gateway to stronger drugs, a belief that is often endorsed by campaign planning officials and health educators. A sample of 418 middle and high school students was randomly assigned to a control video or one of three series of ads, two of which included the gateway message in either an explicit or implicit way. Results did not support the use of the gateway belief in anti-marijuana interventions. Whereas no clear persuasion or priming effects were found for any of the ad sequences, there is some possibility that an explicit gateway argument may actually boomerang. In comparison to the control condition, adolescents in the explicit gateway condition tended to agree less with the gateway message and displayed weaker correlations between anti-marijuana beliefs and their attitude toward marijuana use. The results suggest that the gateway message should not be used in anti-drug interventions. PMID:12746037

  1. Competitive Swarm Optimizer Based Gateway Deployment Algorithm in Cyber-Physical Systems

    PubMed Central

    Huang, Shuqiang; Tao, Ming

    2017-01-01

    Wireless sensor network topology optimization is a highly important issue, and topology control through node selection can improve the efficiency of data forwarding, while saving energy and prolonging lifetime of the network. To address the problem of connecting a wireless sensor network to the Internet in cyber-physical systems, here we propose a geometric gateway deployment based on a competitive swarm optimizer algorithm. The particle swarm optimization (PSO) algorithm has a continuous search feature in the solution space, which makes it suitable for finding the geometric center of gateway deployment; however, its search mechanism is limited to the individual optimum (pbest) and the population optimum (gbest); thus, it easily falls into local optima. In order to improve the particle search mechanism and enhance the search efficiency of the algorithm, we introduce a new competitive swarm optimizer (CSO) algorithm. The CSO search algorithm is based on an inter-particle competition mechanism and can effectively avoid trapping of the population falling into a local optimum. With the improvement of an adaptive opposition-based search and its ability to dynamically parameter adjustments, this algorithm can maintain the diversity of the entire swarm to solve geometric K-center gateway deployment problems. The simulation results show that this CSO algorithm has a good global explorative ability as well as convergence speed and can improve the network quality of service (QoS) level of cyber-physical systems by obtaining a minimum network coverage radius. We also find that the CSO algorithm is more stable, robust and effective in solving the problem of geometric gateway deployment as compared to the PSO or Kmedoids algorithms. PMID:28117735

  2. Competitive Swarm Optimizer Based Gateway Deployment Algorithm in Cyber-Physical Systems.

    PubMed

    Huang, Shuqiang; Tao, Ming

    2017-01-22

    Wireless sensor network topology optimization is a highly important issue, and topology control through node selection can improve the efficiency of data forwarding, while saving energy and prolonging lifetime of the network. To address the problem of connecting a wireless sensor network to the Internet in cyber-physical systems, here we propose a geometric gateway deployment based on a competitive swarm optimizer algorithm. The particle swarm optimization (PSO) algorithm has a continuous search feature in the solution space, which makes it suitable for finding the geometric center of gateway deployment; however, its search mechanism is limited to the individual optimum (pbest) and the population optimum (gbest); thus, it easily falls into local optima. In order to improve the particle search mechanism and enhance the search efficiency of the algorithm, we introduce a new competitive swarm optimizer (CSO) algorithm. The CSO search algorithm is based on an inter-particle competition mechanism and can effectively avoid trapping of the population falling into a local optimum. With the improvement of an adaptive opposition-based search and its ability to dynamically parameter adjustments, this algorithm can maintain the diversity of the entire swarm to solve geometric K -center gateway deployment problems. The simulation results show that this CSO algorithm has a good global explorative ability as well as convergence speed and can improve the network quality of service (QoS) level of cyber-physical systems by obtaining a minimum network coverage radius. We also find that the CSO algorithm is more stable, robust and effective in solving the problem of geometric gateway deployment as compared to the PSO or Kmedoids algorithms.

  3. Remote Sensing Information Gateway: A free application and web service for fast, convenient, interoperable access to large repositories of atmospheric data

    NASA Astrophysics Data System (ADS)

    Plessel, T.; Szykman, J.; Freeman, M.

    2012-12-01

    EPA's Remote Sensing Information Gateway (RSIG) is a widely used free applet and web service for quickly and easily retrieving, visualizing and saving user-specified subsets of atmospheric data - by variable, geographic domain and time range. Petabytes of available data include thousands of variables from a set of NASA and NOAA satellites, aircraft, ground stations and EPA air-quality models. The RSIG applet is used by atmospheric researchers and uses the rsigserver web service to obtain data and images. The rsigserver web service is compliant with the Open Geospatial Consortium Web Coverage Service (OGC-WCS) standard to facilitate data discovery and interoperability. Since rsigserver is publicly accessible, it can be (and is) used by other applications. This presentation describes the architecture and technical implementation details of this successful system with an emphasis on achieving convenience, high-performance, data integrity and security.

  4. A global assessment of market accessibility and market influence for global environmental change studies

    NASA Astrophysics Data System (ADS)

    Verburg, Peter H.; Ellis, Erle C.; Letourneau, Aurelien

    2011-07-01

    Markets influence the global patterns of urbanization, deforestation, agriculture and other land use systems. Yet market influence is rarely incorporated into spatially explicit global studies of environmental change, largely because consistent global data are lacking below the national level. Here we present the first high spatial resolution gridded data depicting market influence globally. The data jointly represent variations in both market strength and accessibility based on three market influence indices derived from an index of accessibility to market locations and national level gross domestic product (purchasing power parity). These indices show strong correspondence with human population density while also revealing several distinct and useful relationships with other global environmental patterns. As market influence grows, the need for high resolution global data on market influence and its dynamics will become increasingly important to understanding and forecasting global environmental change.

  5. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.310 Federal alert gateway. [Reserved] ...

  6. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.310 Federal alert gateway. [Reserved] ...

  7. HOSC DTN Gateway Test Report

    NASA Technical Reports Server (NTRS)

    Pitts, Robert Lee

    2012-01-01

    Goals of this activity: Test the Huntsville Operations Support Center (HOSC) Delay/Disruption Tolerant Networking (DTN) Gateway for operational use Current activity includes: (1) Test the Implementation of a new DTN2 gateway at the HOSC (2) Confirm integration of DTN nodes into the S-band uplink and Ku-band downlink of the ISS for limited use (3) Implement Aggregate Custody Signal to ISS platforms (4) Verify operational support for Colorado University (CU) onboard components (5) Verify ability to support Multi-Purpose End-To- End Robotic Operation Network (METERON) OpsCon-2

  8. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway. [Reserved] ...

  9. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway. [Reserved] ...

  10. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway. [Reserved] ...

  11. The Common Gateway Interface (CGI) for Enhancing Access to Database Servers via the World Wide Web (WWW).

    ERIC Educational Resources Information Center

    Machovec, George S., Ed.

    1995-01-01

    Explains the Common Gateway Interface (CGI) protocol as a set of rules for passing information from a Web server to an external program such as a database search engine. Topics include advantages over traditional client/server solutions, limitations, sample library applications, and sources of information from the Internet. (LRW)

  12. Mental health service utilization of Somali adolescents: religion, community, and school as gateways to healing.

    PubMed

    Ellis, B Heidi; Lincoln, Alisa K; Charney, Meredith E; Ford-Paz, Rebecca; Benson, Molly; Strunin, Lee

    2010-11-01

    This mixed-method study examines the utility of the Gateway Provider Model (GPM) in understanding service utilization and pathways to help for Somali refugee adolescents. Somali adolescents living in the Northeastern United States, and their caregivers, were interviewed. Results revealed low rates of use of mental health services. However other sources of help, such as religious and school personnel, were accessed more frequently. The GPM provides a helpful model for understanding refugee youth access to services, and an elaborated model is presented showing how existing pathways to help could be built upon to improve refugee youth access to services.

  13. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

  14. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

  15. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

  16. Web Access to RSIG Data

    EPA Pesticide Factsheets

    Remote Sensing Information Gateway, a tool that allows scientists, researchers and decision makers to access a variety of multi-terabyte, environmental datasets and to subset the data and obtain only needed variables, greatly improving the download time.

  17. Accessing global data from accelerator devices

    DOEpatents

    Bertolli, Carlo; O'Brien, John K.; Sallenave, Olivier H.; Sura, Zehra N.

    2016-12-06

    An aspect includes a table of contents (TOC) that was generated by a compiler being received at an accelerator device. The TOC includes an address of global data in a host memory space. The global data is copied from the address in the host memory space to an address in the device memory space. The address in the host memory space is obtained from the received TOC. The received TOC is updated to indicate that global data is stored at the address in the device memory space. A kernel that accesses the global data from the address in the device memory space is executed. The address in the device memory space is obtained based on contents of the updated TOC. When the executing is completed, the global data from the address in the device memory space is copied to the address in the host memory space.

  18. Accessing global data from accelerator devices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bertolli, Carlo; O'Brien, John K.; Sallenave, Olivier H.

    2016-12-06

    An aspect includes a table of contents (TOC) that was generated by a compiler being received at an accelerator device. The TOC includes an address of global data in a host memory space. The global data is copied from the address in the host memory space to an address in the device memory space. The address in the host memory space is obtained from the received TOC. The received TOC is updated to indicate that global data is stored at the address in the device memory space. A kernel that accesses the global data from the address in the devicemore » memory space is executed. The address in the device memory space is obtained based on contents of the updated TOC. When the executing is completed, the global data from the address in the device memory space is copied to the address in the host memory space.« less

  19. Open Smart Energy Gateway (OpenSEG)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    The Open Smart Energy Gateway (OpenSEG) aims to provide near-real time smart meter data to consumers without the delays or latencies associated with it being transported to the utility data center and then back to the consumer's application. To do this, the gateway queries the local Smart Meter to which it is bound to get energy consumption information at pre-defined intervals (minimum interval is 4 seconds). OpenSEG then stores the resulting data internally for retrieval by an external application.

  20. PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways): Introduction and overview

    NASA Astrophysics Data System (ADS)

    Ó Cofaigh, Colm; Briner, Jason P.; Kirchner, Nina; Lucchi, Renata G.; Meyer, Hanno; Kaufman, Darrell S.

    2016-09-01

    This special issue relates to the Second International Conference of the PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways) network which was held in Trieste, Italy in 2014. Twenty five papers are included and they address topics under four main themes: (1) The growth and decay of Arctic ice sheets; (2) Arctic sea ice and palaeoceanography; (3) Terrestrial Arctic environments and permafrost change; and (4) Holocene Arctic environmental change. Geographically the focus is circum-Arctic; the special issue includes detailed regional studies from Greenland, Scandinavia, Russia, and Arctic North America and the adjoining seas, as well as a series of synthesis-type, review papers on Fennoscandian Ice Sheet deglaciation and Holocene Arctic palaeo-climate change. The methodologies employed are diverse and include marine sediment core and geophysical investigations, terrestrial glacial geology and geomorphology, isotopic analysis of ground ice, palaeo-ecological analysis of lacustrine and terrestrial sedimentary archives, geochronology and numerical ice sheet modeling.

  1. Globalizing Higher Education Access in South-West Nigeria

    ERIC Educational Resources Information Center

    Olayiwola, Mohammed Mubashiru; Kolawole, Oladipupo Fatai; Moyosore, Onabanjo Florence

    2013-01-01

    Education is central to national interest and cannot be solely determined by market forces. Thus, the role of the state in making education policy and funding education to embrace access cannot be overemphasized. The influence of globalization on Higher Education access in Southwest Nigeria as it affects policy making was investigated through the…

  2. An integrated gateway for various PHDs in U-healthcare environments.

    PubMed

    Park, KeeHyun; Pak, JuGeon

    2012-01-01

    We propose an integrated gateway for various personal health devices (PHDs). This gateway receives measurements from various PHDs and conveys them to a remote monitoring server (MS). It provides two kinds of transmission modes: immediate transmission and integrated transmission. The former mode operates if a measurement exceeds a predetermined threshold or in the case of an emergency. In the latter mode, the gateway retains the measurements instead of forwarding them. When the reporting time comes, the gateway extracts all the stored measurements, integrates them into one message, and transmits the integrated message to the MS. Through this mechanism, the transmission overhead can be reduced. On the basis of the proposed gateway, we construct a u-healthcare system comprising an activity monitor, a medication dispenser, and a pulse oximeter. The evaluation results show that the size of separate messages from various PHDs is reduced through the integration process, and the process does not require much time; the integration time is negligible.

  3. An Integrated Gateway for Various PHDs in U-Healthcare Environments

    PubMed Central

    Park, KeeHyun; Pak, JuGeon

    2012-01-01

    We propose an integrated gateway for various personal health devices (PHDs). This gateway receives measurements from various PHDs and conveys them to a remote monitoring server (MS). It provides two kinds of transmission modes: immediate transmission and integrated transmission. The former mode operates if a measurement exceeds a predetermined threshold or in the case of an emergency. In the latter mode, the gateway retains the measurements instead of forwarding them. When the reporting time comes, the gateway extracts all the stored measurements, integrates them into one message, and transmits the integrated message to the MS. Through this mechanism, the transmission overhead can be reduced. On the basis of the proposed gateway, we construct a u-healthcare system comprising an activity monitor, a medication dispenser, and a pulse oximeter. The evaluation results show that the size of separate messages from various PHDs is reduced through the integration process, and the process does not require much time; the integration time is negligible. PMID:22899891

  4. Mentoring the Next Generation of Science Gateway Developers and Users

    NASA Astrophysics Data System (ADS)

    Hayden, L. B.; Jackson-Ward, F.

    2016-12-01

    The Science Gateway Institute (SGW-I) for the Democratization and Acceleration of Science was a SI2-SSE Collaborative Research conceptualization award funded by NSF in 2012. From 2012 through 2015, we engaged interested members of the science and engineering community in a planning process for a Science Gateway Community Institute (SGCI). Science Gateways provide Web interfaces to some of the most sophisticated cyberinfrastructure resources. They interact with remotely executing science applications on supercomputers, they connect to remote scientific data collections, instruments and sensor streams, and support large collaborations. Gateways allow scientists to concentrate on the most challenging science problems while underlying components such as computing architectures and interfaces to data collection changes. The goal of our institute was to provide coordinating activities across the National Science Foundation, eventually providing services more broadly to projects funded by other agencies. SGW-I has succeeded in identifying two underrepresented communities of future gateway designers and users. The Association of Computer and Information Science/Engineering Departments at Minority Institutions (ADMI) was identified as a source of future gateway designers. The National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChE) was identified as a community of future science gateway users. SGW-I efforts to engage NOBCChE and ADMI faculty and students in SGW-I are now woven into the workforce development component of SGCI. SGCI (ScienceGateways.org ) is a collaboration of six universities, led by San Diego Supercomputer Center. The workforce development component is led by Elizabeth City State University (ECSU). ECSU efforts focus is on: Produce a model of engagement; Integration of research into education; and Mentoring of students while aggressively addressing diversity. This paper documents the outcome of the SGW

  5. E-DECIDER Decision Support Gateway For Earthquake Disaster Response

    NASA Astrophysics Data System (ADS)

    Glasscoe, M. T.; Stough, T. M.; Parker, J. W.; Burl, M. C.; Donnellan, A.; Blom, R. G.; Pierce, M. E.; Wang, J.; Ma, Y.; Rundle, J. B.; Yoder, M. R.

    2013-12-01

    Earthquake Data Enhanced Cyber-Infrastructure for Disaster Evaluation and Response (E-DECIDER) is a NASA-funded project developing capabilities for decision-making utilizing remote sensing data and modeling software in order to provide decision support for earthquake disaster management and response. E-DECIDER incorporates earthquake forecasting methodology and geophysical modeling tools developed through NASA's QuakeSim project in order to produce standards-compliant map data products to aid in decision-making following an earthquake. Remote sensing and geodetic data, in conjunction with modeling and forecasting tools, help provide both long-term planning information for disaster management decision makers as well as short-term information following earthquake events (i.e. identifying areas where the greatest deformation and damage has occurred and emergency services may need to be focused). E-DECIDER utilizes a service-based GIS model for its cyber-infrastructure in order to produce standards-compliant products for different user types with multiple service protocols (such as KML, WMS, WFS, and WCS). The goal is to make complex GIS processing and domain-specific analysis tools more accessible to general users through software services as well as provide system sustainability through infrastructure services. The system comprises several components, which include: a GeoServer for thematic mapping and data distribution, a geospatial database for storage and spatial analysis, web service APIs, including simple-to-use REST APIs for complex GIS functionalities, and geoprocessing tools including python scripts to produce standards-compliant data products. These are then served to the E-DECIDER decision support gateway (http://e-decider.org), the E-DECIDER mobile interface, and to the Department of Homeland Security decision support middleware UICDS (Unified Incident Command and Decision Support). The E-DECIDER decision support gateway features a web interface that

  6. Global access to surgical care: a modelling study.

    PubMed

    Alkire, Blake C; Raykar, Nakul P; Shrime, Mark G; Weiser, Thomas G; Bickler, Stephen W; Rose, John A; Nutt, Cameron T; Greenberg, Sarah L M; Kotagal, Meera; Riesel, Johanna N; Esquivel, Micaela; Uribe-Leitz, Tarsicio; Molina, George; Roy, Nobhojit; Meara, John G; Farmer, Paul E

    2015-06-01

    More than 2 billion people are unable to receive surgical care based on operating theatre density alone. The vision of the Lancet Commission on Global Surgery is universal access to safe, affordable surgical and anaesthesia care when needed. We aimed to estimate the number of individuals worldwide without access to surgical services as defined by the Commission's vision. We modelled access to surgical services in 196 countries with respect to four dimensions: timeliness, surgical capacity, safety, and affordability. We built a chance tree for each country to model the probability of surgical access with respect to each dimension, and from this we constructed a statistical model to estimate the proportion of the population in each country that does not have access to surgical services. We accounted for uncertainty with one-way sensitivity analyses, multiple imputation for missing data, and probabilistic sensitivity analysis. At least 4·8 billion people (95% posterior credible interval 4·6-5·0 [67%, 64-70]) of the world's population do not have access to surgery. The proportion of the population without access varied widely when stratified by epidemiological region: greater than 95% of the population in south Asia and central, eastern, and western sub-Saharan Africa do not have access to care, whereas less than 5% of the population in Australasia, high-income North America, and western Europe lack access. Most of the world's population does not have access to surgical care, and access is inequitably distributed. The near absence of access in many low-income and middle-income countries represents a crisis, and as the global health community continues to support the advancement of universal health coverage, increasing access to surgical services will play a central role in ensuring health care for all. None. Copyright © 2015 Alkire et al. Open Access article distributed under the terms of CC BY. Published by Elsevier Ltd.. All rights reserved.

  7. Mapping, monitoring, and modeling Western Gateway Community landscape dynamics

    USGS Publications Warehouse

    Hester, David J.

    2013-01-01

    Federal public lands in the western United States are becoming increasingly surrounded by Gateway Communities. These communities are undergoing landscape change due to population growth, economic growth, and the resulting land-use development. Socioeconomic, demographic, and land-use changes in Gateway Communities are often perceived as threats to Federal land resources, natural amenities, cultural resources, and recreational opportunities. However, land-surface disturbances on Federal public lands, such as conventional and alternative energy development (which impact surrounding Gateway Communities), are also environmental and societal issues that Federal land and adjacent regional community planners need to consider in their long-range land-use planning.

  8. A Robotic Communications Gateway for Ocean Observations

    NASA Astrophysics Data System (ADS)

    Orcutt, J. A.; Berger, J.; Laske, G.; Babcock, J.

    2015-12-01

    We describe a new technology that can provide real-time telemetry of sensor data from the ocean bottom. The breakthrough technology that makes this system possible is an autonomous surface vehicle called the Wave Glider developed by Liquid Robotics, Inc. of Sunnyvale, CA., which harvests wave and solar energy for motive and electrical power. The free-floating surface communications gateway uses a Liquid Robotics wave glider comprising a surfboard-sized float towed by a tethered, submerged glider, which converts wave motion into thrust. For navigation, the wave glider is equipped with a small computer, a GPS receiver, a rudder, solar panels and batteries, and an Iridium satellite modem. Acoustic communications connect the subsea instruments and the surface gateway while communications between the gateway and land are provided by the Iridium satellite constellation. Wave gliders have demonstrated trans-oceanic range and long-term station keeping capabilities. The topside acoustics communications package is mounted in a shallow tow body, which uses a WHOI micro modem and a Benthos low frequency, directional transducer. A matching bottom side modem and transducer are mounted on the ocean bottom package. Tests of the surface gateway in 4000 m of water demonstrated an acoustic efficiency of approximately 256 bits/J. For example, it has the ability to send four channels of compressed, one sample per second data from the ocean bottom to the gateway with an average power draw of approximately 0.36 W and a latency of about three minutes. This gateway is used to send near-real-time data from a broadband ocean bottom seismic observatory; we are presently designing and constructing a seafloor package with a two-year operational life. We have found that for frequencies f where f<10mHz, 35mHz < f < 120mHz and f>~3Hz, the vertical component, seafloor system noise characteristics are generally superior to similar observatories on land. Increasing the density of these stations over

  9. Global Trends in Space Access and Utilization

    NASA Technical Reports Server (NTRS)

    Rahman, Shamim A.; Keim, Nicholas S.; Zeender, Peter E.

    2010-01-01

    In the not-so-distant past, space access and air/space technology superiority were within the purview of the U.S. and former Soviet Union's respective space agencies, both vying for global leadership in space exploitation. In more recent years, with the emergence of the European Space Agency (ESA) member countries and Asian countries joining the family of space-faring nations, it is truer now more than ever that space access and utilization has become a truly global enterprise. In fact, according to the Space Report 2007, this enterprise is a $251-billion economy. It is possible to gauge the vitality of worldwide efforts from open sources in today's transparent, media-based society. In particular, print and web broadcasters regularly report and catalog global space activities for defense and civil purposes. For the purposes of this paper, a representative catalog of missions is used to illustrate the nature of the emerging "globalization." This paper highlights global trends in terms of not only the providers of space access, but also the end-users for the various recently accomplished missions. With well over 50 launches per year, in recent years, the launch-log reveals a surprising percentage of "cooperative or co-dependent missions" where different agencies, countries, and/or commercial entities are so engaged presumably to the benefit of all who participate. Statistics are cited and used to show that recently over d0% of the 50-plus missions involved multiple nations working collectively to deliver payloads to orbit. Observers, space policy professionals, and space agency leaders have eloquently proposed that it might require the combined resources and talents of multiple nations to advance human exploration goals beyond low earth orbit. This paper does not intend to offer new information with respect to whether international collaboration is necessary but to observe that, in continuing to monitor global trends, the results seem to support the thesis that a

  10. Alcohol as a Gateway Drug: A Study of US 12th Graders

    ERIC Educational Resources Information Center

    Kirby, Tristan; Barry, Adam E.

    2012-01-01

    Background: The Gateway Drug Theory suggests that licit drugs, such as tobacco and alcohol, serve as a "gateway" toward the use of other, illicit drugs. However, there remains some discrepancy regarding which drug--alcohol, tobacco, or even marijuana--serves as the initial "gateway" drug subsequently leading to the use of…

  11. Enhancement of Mutual Discovery, Search, and Access of Data for Users of NASA and GEOSS-Cataloged Data Systems

    NASA Technical Reports Server (NTRS)

    Teng, William; Maidment, David; Rodell, Matthew; Strub, Richard; Arctur, David; Ames, Daniel; Rui, Hualan; Vollmer, Bruce; Seiler, Edward

    2014-01-01

    An ongoing NASA-funded Data Rods (time series) project has demonstrated the removal of a longstanding barrier to accessing NASA data (i.e., accessing archived time-step array data as point-time series) for selected variables of the North American and Global Land Data Assimilation Systems (NLDAS and GLDAS, respectively) and other NASA data sets. Data rods are pre-generated or generated on-the-fly (OTF), leveraging the NASA Simple Subset Wizard (SSW), a gateway to NASA data centers. Data rods Web services are accessible through the CUAHSI Hydrologic Information System (HIS) and the Goddard Earth Sciences Data and Information Services Center (GES DISC) but are not easily discoverable by users of other non-NASA data systems. An ongoing GEOSS Water Services project aims to develop a distributed, global registry of water data, map, and modeling services cataloged using the standards and procedures of the Open Geospatial Consortium and the World Meteorological Organization. Preliminary work has shown GEOSS can be leveraged to help provide access to data rods. A new NASA-funded project is extending this early work.

  12. The VERCE Science Gateway: enabling user friendly seismic waves simulations across European HPC infrastructures

    NASA Astrophysics Data System (ADS)

    Spinuso, Alessandro; Krause, Amy; Ramos Garcia, Clàudia; Casarotti, Emanuele; Magnoni, Federica; Klampanos, Iraklis A.; Frobert, Laurent; Krischer, Lion; Trani, Luca; David, Mario; Leong, Siew Hoon; Muraleedharan, Visakh

    2014-05-01

    The EU-funded project VERCE (Virtual Earthquake and seismology Research Community in Europe) aims to deploy technologies which satisfy the HPC and data-intensive requirements of modern seismology. As a result of VERCE's official collaboration with the EU project SCI-BUS, access to computational resources, like local clusters and international infrastructures (EGI and PRACE), is made homogeneous and integrated within a dedicated science gateway based on the gUSE framework. In this presentation we give a detailed overview on the progress achieved with the developments of the VERCE Science Gateway, according to a use-case driven implementation strategy. More specifically, we show how the computational technologies and data services have been integrated within a tool for Seismic Forward Modelling, whose objective is to offer the possibility to perform simulations of seismic waves as a service to the seismological community. We will introduce the interactive components of the OGC map based web interface and how it supports the user with setting up the simulation. We will go through the selection of input data, which are either fetched from federated seismological web services, adopting community standards, or provided by the users themselves by accessing their own document data store. The HPC scientific codes can be selected from a number of waveform simulators, currently available to the seismological community as batch tools or with limited configuration capabilities in their interactive online versions. The results will be staged out from the HPC via a secure GridFTP transfer to a VERCE data layer managed by iRODS. The provenance information of the simulation will be automatically cataloged by the data layer via NoSQL techonologies. We will try to demonstrate how data access, validation and visualisation can be supported by a general purpose provenance framework which, besides common provenance concepts imported from the OPM and the W3C-PROV initiatives, also offers

  13. Science gateways for semantic-web-based life science applications.

    PubMed

    Ardizzone, Valeria; Bruno, Riccardo; Calanducci, Antonio; Carrubba, Carla; Fargetta, Marco; Ingrà, Elisa; Inserra, Giuseppina; La Rocca, Giuseppe; Monforte, Salvatore; Pistagna, Fabrizio; Ricceri, Rita; Rotondo, Riccardo; Scardaci, Diego; Barbera, Roberto

    2012-01-01

    In this paper we present the architecture of a framework for building Science Gateways supporting official standards both for user authentication and authorization and for middleware-independent job and data management. Two use cases of the customization of the Science Gateway framework for Semantic-Web-based life science applications are also described.

  14. Analysis of Random Drop for Gateway Congestion Control

    DTIC Science & Technology

    1989-11-01

    effective congest)on control policies. Currently No Gateway Policy is used to relieve and signal congestion, which leads to unfair service to the...early application of the policy removes the pressure of congestion relief and allows more accurate signaling of congestion. ’ To be used effectively ...prompted the need for more effective congestion control policies. Currently No Gateway Policy is used to relieve and signal congestion, which leads to

  15. Formal Semantics and Implementation of BPMN 2.0 Inclusive Gateways

    NASA Astrophysics Data System (ADS)

    Christiansen, David Raymond; Carbone, Marco; Hildebrandt, Thomas

    We present the first direct formalization of the semantics of inclusive gateways as described in the Business Process Modeling Notation (BPMN) 2.0 Beta 1 specification. The formal semantics is given for a minimal subset of BPMN 2.0 containing just the inclusive and exclusive gateways and the start and stop events. By focusing on this subset we achieve a simple graph model that highlights the particular non-local features of the inclusive gateway semantics. We sketch two ways of implementing the semantics using algorithms based on incrementally updated data structures and also discuss distributed communication-based implementations of the two algorithms.

  16. Deep Space Gateway Science Opportunities

    NASA Technical Reports Server (NTRS)

    Quincy, C. D.; Charles, J. B.; Hamill, Doris; Sidney, S. C.

    2018-01-01

    The NASA Life Sciences Research Capabilities Team (LSRCT) has been discussing deep space research needs for the last two years. NASA's programs conducting life sciences studies - the Human Research Program, Space Biology, Astrobiology, and Planetary Protection - see the Deep Space Gateway (DSG) as affording enormous opportunities to investigate biological organisms in a unique environment that cannot be replicated in Earth-based laboratories or on Low Earth Orbit science platforms. These investigations may provide in many cases the definitive answers to risks associated with exploration and living outside Earth's protective magnetic field. Unlike Low Earth Orbit or terrestrial locations, the Gateway location will be subjected to the true deep space spectrum and influence of both galactic cosmic and solar particle radiation and thus presents an opportunity to investigate their long-term exposure effects. The question of how a community of biological organisms change over time within the harsh environment of space flight outside of the magnetic field protection can be investigated. The biological response to the absence of Earth's geomagnetic field can be studied for the first time. Will organisms change in new and unique ways under these new conditions? This may be specifically true on investigations of microbial communities. The Gateway provides a platform for microbiology experiments both inside, to improve understanding of interactions between microbes and human habitats, and outside, to improve understanding of microbe-hardware interactions exposed to the space environment.

  17. MIRATE: MIps RATional dEsign Science Gateway.

    PubMed

    Busato, Mirko; Distefano, Rosario; Bates, Ferdia; Karim, Kal; Bossi, Alessandra Maria; López Vilariño, José Manuel; Piletsky, Sergey; Bombieri, Nicola; Giorgetti, Alejandro

    2018-06-13

    Molecularly imprinted polymers (MIPs) are high affinity robust synthetic receptors, which can be optimally synthesized and manufactured more economically than their biological equivalents (i.e. antibody). In MIPs production, rational design based on molecular modeling is a commonly employed technique. This mostly aids in (i) virtual screening of functional monomers (FMs), (ii) optimization of monomer-template ratio, and (iii) selectivity analysis. We present MIRATE, an integrated science gateway for the intelligent design of MIPs. By combining and adapting multiple state-of-the-art bioinformatics tools into automated and innovative pipelines, MIRATE guides the user through the entire process of MIPs' design. The platform allows the user to fully customize each stage involved in the MIPs' design, with the main goal to support the synthesis in the wet-laboratory. MIRATE is freely accessible with no login requirement at http://mirate.di.univr.it/. All major browsers are supported.

  18. SCORPION persistent surveillance system with universal gateway

    NASA Astrophysics Data System (ADS)

    Coster, Michael; Chambers, Jon; Winters, Michael; Belesi, Joe

    2008-04-01

    This paper addresses benefits derived from the universal gateway utilized in Northrop Grumman Systems Corporation's (NGSC) SCORPION, a persistent surveillance and target recognition system produced by the Xetron campus in Cincinnati, Ohio. SCORPION is currently deployed in Operations Iraqi Freedom (OIF) and Enduring Freedom (OEF). The SCORPION universal gateway is a flexible, field programmable system that provides integration of over forty Unattended Ground Sensor (UGS) types from a variety of manufacturers, multiple visible and thermal electro-optical (EO) imagers, and numerous long haul satellite and terrestrial communications links, including the Army Research Lab (ARL) Blue Radio. Xetron has been integrating best in class sensors with this universal gateway to provide encrypted data exfiltration and remote sensor command and control since 1998. SCORPION data can be distributed point to point, or to multiple Common Operational Picture (COP) systems, including Command and Control Personal Computer (C2PC), Common Data Interchange Format for the Situational Awareness Display (CDIF/SAD), Force XXI Battle Command Brigade and Below (FBCB2), Defense Common Ground Systems (DCGS), and Remote Automated Position Identification System (RAPIDS).

  19. Building a gateway with open source software for secure-DICOM communication over insecure networks

    NASA Astrophysics Data System (ADS)

    Emmel, Dirk; Ricke, Jens; Stohlmann, Lutz; Haderer, Alexander; Felix, Roland

    2002-05-01

    For Teleradiology the exchange of DICOM-images is needed for several purposes. Existing solutions often don't consider about the needs for data security and data privacy. Communication is done without any encryption over insecure networks or with encryption using proprietary solutions, which reduces the data communication possibilities to partners with the same equipment. Our goal was to build a gateway, which offers a transparent solution for secure DICOM-communication in a heterogeneous environment We developed a PC-based gateway system with DICOM-communication to the in-house network and secure DICOM communication for the communication over the insecure network. One gateway installed at each location is responsible for encryption/decryption. The sender just transfers the image data over the DICOM protocol to the local gateway. The gateway forwards the data to the gateway on the destination site using the secure DICOM protocol, which is part of the DICOM standard. The receiving gateway forwards the image data to the final destination again using the DICOM-Protocol. The gateway is based on Open Source software and runs under several operating systems. Our experience shows a reliable solution, which solves security issues for DICOM communication of image data and integrates seamless into a heterogeneous DICOM environment.

  20. Building Global Support for Open Data Access

    NASA Astrophysics Data System (ADS)

    Key, E.; Samors, R. J.; Seltzer, C. E.; Orr, B. J.

    2017-12-01

    The Belmont Forum, a global partnership of funding organizations, international science councils, and regional consortia is committed to the advancement of international transdisciplinary research providing knowledge for understanding, mitigating and adapting to global environmental change. The Forum is also committed to ensuring appropriate, recognizable credit is awarded to the creators of that data, each and every time it is used. At its 2015 plenary meeting, the Belmont Forum agreed on and adopted an open data policy and principles. The principles are designed to widen access to data and promote its long-term preservation in global change research; help improve data management and exploitation; coordinate and integrate disparate organizational and technical elements; fill critical global e-infrastructure gaps; share best practices; and foster new data literacy. To help implement the policy and principles, the Belmont Forum has established the e-Infrastructures and Data Management (e-I&DM) Initiative which will leverage existing knowledge and resources to illuminate achievable, reproducible systems for effective, sustainable data management practices. The overall objective of the e-I&DM Initiative is to provide advice and recommendations to the Belmont Forum member and partner organizations regarding policies, programs, procedures that could be adopted to accelerate open data sharing, data reproducibility, data curation, and other aspects of long-term data management and access. This presentation will explore current Belmont Forum activities through the e-I&DM Initiative to develop policies and practices that could be adopted by funders, publishers and researchers alike that will lead to increased data sharing with more widespread data citation/attribution - giving credit where credit is due.

  1. Shield Optimization in Simple Geometry for the Gateway Concept

    NASA Technical Reports Server (NTRS)

    Tripathi, R. K.; Simonsen, L. C.; Nealy, J. E.; Troutman, P. A.; Wilson, J. W.

    2002-01-01

    The great cost of added radiation shielding is a potential limiting factor in many deep space missions. For this enabling technology, we are developing tools for optimized shield design over multi-segmented missions involving multiple work and living areas in the transport and duty phase of various space missions. The total shield mass over all pieces of equipment and habitats is optimized subject to career dose and dose rate constraints. Preliminary studies of deep space missions indicate that for long duration space missions, improved shield materials will be required. The details of this new method and its impact on space missions and other technologies will be discussed. This study will provide a vital tool for evaluating Gateway designs in their usage context. Providing protection against the hazards of space radiation is one of the challenges to the Gateway infrastructure designs. We will use the mission optimization software to scope the impact of Gateway operations on human exposures and the effectiveness of alternate shielding materials on Gateway infrastructure designs. This study will provide a guide to the effectiveness of multifunctional materials in preparation to more detailed geometry studies in progress.

  2. Updates to SCORPION persistent surveillance system with universal gateway

    NASA Astrophysics Data System (ADS)

    Coster, Michael; Chambers, Jon; Winters, Michael; Brunck, Al

    2008-10-01

    This paper addresses benefits derived from the universal gateway utilized in Northrop Grumman Systems Corporation's (NGSC) SCORPION, a persistent surveillance and target recognition system produced by the Xetron campus in Cincinnati, Ohio. SCORPION is currently deployed in Operations Iraqi Freedom (OIF) and Enduring Freedom (OEF). The SCORPION universal gateway is a flexible, field programmable system that provides integration of over forty Unattended Ground Sensor (UGS) types from a variety of manufacturers, multiple visible and thermal electro-optical (EO) imagers, and numerous long haul satellite and terrestrial communications links, including the Army Research Lab (ARL) Blue Radio. Xetron has been integrating best in class sensors with this universal gateway to provide encrypted data exfiltration to Common Operational Picture (COP) systems and remote sensor command and control since 1998. In addition to being fed to COP systems, SCORPION data can be visualized in the Common sensor Status (CStat) graphical user interface that allows for viewing and analysis of images and sensor data from up to seven hundred SCORPION system gateways on single or multiple displays. This user friendly visualization enables a large amount of sensor data and imagery to be used as actionable intelligence by a minimum number of analysts.

  3. The VERCE platform: Enabling Computational Seismology via Streaming Workflows and Science Gateways

    NASA Astrophysics Data System (ADS)

    Spinuso, Alessandro; Filgueira, Rosa; Krause, Amrey; Matser, Jonas; Casarotti, Emanuele; Magnoni, Federica; Gemund, Andre; Frobert, Laurent; Krischer, Lion; Atkinson, Malcolm

    2015-04-01

    The VERCE project is creating an e-Science platform to facilitate innovative data analysis and coding methods that fully exploit the wealth of data in global seismology. One of the technologies developed within the project is the Dispel4Py python library, which allows to describe abstract stream-based workflows for data-intensive applications and to execute them in a distributed environment. At runtime Dispel4Py is able to map workflow descriptions dynamically onto a number of computational resources (Apache Storm clusters, MPI powered clusters, and shared-memory multi-core machines, single-core machines), setting it apart from other workflow frameworks. Therefore, Dispel4Py enables scientists to focus on their computation instead of being distracted by details of the computing infrastructure they use. Among the workflows developed with Dispel4Py in VERCE, we mention here those for Seismic Ambient Noise Cross-Correlation and MISFIT calculation, which address two data-intensive problems that are common in computational seismology. The former, also called Passive Imaging, allows the detection of relative seismic-wave velocity variations during the time of recording, to be associated with the stress-field changes that occurred in the test area. The MISFIT instead, takes as input the synthetic seismograms generated from HPC simulations for a certain Earth model and earthquake and, after a preprocessing stage, compares them with real observations in order to foster subsequent model updates and improvement (Inversion). The VERCE Science Gateway exposes the MISFIT calculation workflow as a service, in combination with the simulation phase. Both phases can be configured, controlled and monitored by the user via a rich user interface which is integrated within the gUSE Science Gateway framework, hiding the complexity of accessing third parties data services, security mechanisms and enactment on the target resources. Thanks to a modular extension to the Dispel4Py framework

  4. Development of the gateway recycling cloning system for multiple linking of expression cassettes in a defined order, and direction on gateway compatible binary vectors.

    PubMed

    Kimura, Tetsuya; Nakao, Akihide; Murata, Sachiko; Kobayashi, Yasuyuki; Tanaka, Yuji; Shibahara, Kenta; Kawazu, Tetsu; Nakagawa, Tsuyoshi

    2013-01-01

    We developed the Gateway recycling cloning system, which allows multiple linking of expression cassettes by multiple rounds of the Gateway LR reaction. Employing this system, the recycling donor vector pRED419 was subjected to the first LR reaction with an attR1-attR2 type destination vector. Then conversion vector pCON was subjected to an LR reaction to restore the attR1-attR2 site on the destination vector for the next cloning cycle. By repetition of these two simple steps, we linked four expression cassettes of a reporter gene in Gateway binary vector pGWB1, introduced the constructs into tobacco BY-2 cells, and observed the expression of transgenes.

  5. Efficient Memory Access with NumPy Global Arrays using Local Memory Access

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daily, Jeffrey A.; Berghofer, Dan C.

    This paper discusses the work completed working with Global Arrays of data on distributed multi-computer systems and improving their performance. The tasks completed were done at Pacific Northwest National Laboratory in the Science Undergrad Laboratory Internship program in the summer of 2013 for the Data Intensive Computing Group in the Fundamental and Computational Sciences DIrectorate. This work was done on the Global Arrays Toolkit developed by this group. This toolkit is an interface for programmers to more easily create arrays of data on networks of computers. This is useful because scientific computation is often done on large amounts of datamore » sometimes so large that individual computers cannot hold all of it. This data is held in array form and can best be processed on supercomputers which often consist of a network of individual computers doing their computation in parallel. One major challenge for this sort of programming is that operations on arrays on multiple computers is very complex and an interface is needed so that these arrays seem like they are on a single computer. This is what global arrays does. The work done here is to use more efficient operations on that data that requires less copying of data to be completed. This saves a lot of time because copying data on many different computers is time intensive. The way this challenge was solved is when data to be operated on with binary operations are on the same computer, they are not copied when they are accessed. When they are on separate computers, only one set is copied when accessed. This saves time because of less copying done although more data access operations were done.« less

  6. How leaky is the health career pipeline? Minority student achievement in college gateway courses.

    PubMed

    Alexander, Charles; Chen, Eric; Grumbach, Kevin

    2009-06-01

    To determine whether underrepresented minority (URM) students receive lower grades than do non-URM students in college prehealth gateway courses; the extent to which lower grade performance might be explained by the differences in precollege academic achievement; and whether URM students are less likely than non-URM students to persist in completing at least four gateway courses. Administrative data were obtained from six California colleges on 15,000 college students who matriculated in the 1999-2000 or 2000-2001 academic years and enrolled in at least one college course required for application to medical or dental school ("gateway" courses). Students were compared across ethnic groups in gateway course grade performance and persistence in completing at least four gateway courses, using regression methods to control for students' college admission test scores and caliber of high school attended. URM students received significantly lower grades on average in gateway courses than did white students. This gap persisted after adjusting for measures of prior academic performance. However, URM students were nearly as likely as white students to persist in completing at least four gateway courses. After accounting for the lower grades of URM students in their initial classes, URM students were more likely than white students to complete four or more gateway courses. URM students experienced academic challenges, but many persist in their prehealth courses despite these challenges. Interventions at the college level to support URM student performance in gateway courses are particularly important for increasing the diversity of medical and dental schools.

  7. 78 FR 57371 - Agency Information Collection Activities; Comment Request; Student Aid Internet Gateway (SAIG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ...; Comment Request; Student Aid Internet Gateway (SAIG) Enrollment Document AGENCY: Federal Student Aid (FSA... Internet Gateway (SAIG) Enrollment Document. OMB Control Number: 1845-0002. Type of Review: A revision of... Internet Gateway (SAIG) allows eligible entities to securely exchange Title IV, Higher Education Act (HEA...

  8. Deep Space Gateway "Recycler" Mission

    NASA Astrophysics Data System (ADS)

    Graham, L.; Fries, M.; Hamilton, J.; Landis, R.; John, K.; O'Hara, W.

    2018-02-01

    Use of the Deep Space Gateway provides a hub for a reusable planetary sample return vehicle for missions to gather star dust as well as samples from various parts of the solar system including main belt asteroids, near-Earth asteroids, and Mars moon.

  9. THE REMOTE SENSING DATA GATEWAY

    EPA Science Inventory

    The EPA Remote Sensing Data Gateway (RSDG) is a pilot project in the National Exposure Research Laboratory (NERL) to develop a comprehensive data search, acquisition, delivery and archive mechanism for internal, national and international sources of remote sensing data for the co...

  10. Expansion of the gateway multisite recombination cloning toolkit.

    PubMed

    Shearin, Harold K; Dvarishkis, Alisa R; Kozeluh, Craig D; Stowers, R Steven

    2013-01-01

    Precise manipulation of transgene expression in genetic model organisms has led to advances in understanding fundamental mechanisms of development, physiology, and genetic disease. Transgene construction is, however, a precondition of transgene expression, and often limits the rate of experimental progress. Here we report an expansion of the modular Gateway MultiSite recombination-cloning platform for high efficiency transgene assembly. The expansion includes two additional destination vectors and entry clones for the LexA binary transcription system, among others. These new tools enhance the expression levels possible with Gateway MultiSite generated transgenes and make possible the generation of LexA drivers and reporters with Gateway MultiSite cloning. In vivo data from transgenic Drosophila functionally validating each novel component are presented and include neuronal LexA drivers, LexAop2 red and green fluorescent synaptic vesicle reporters, TDC2 and TRH LexA, GAL4, and QF drivers, and LexAop2, UAS, and QUAS channelrhodopsin2 T159C reporters.

  11. [Development of a secure and cost-effective infrastructure for the access of arbitrary web-based image distribution systems].

    PubMed

    Hackländer, T; Kleber, K; Schneider, H; Demabre, N; Cramer, B M

    2004-08-01

    To build an infrastructure that enables radiologists on-call and external users a teleradiological access to the HTML-based image distribution system inside the hospital via internet. In addition, no investment costs should arise on the user side and the image data should be sent renamed using cryptographic techniques. A pure HTML-based system manages the image distribution inside the hospital, with an open source project extending this system through a secure gateway outside the firewall of the hospital. The gateway handles the communication between the external users and the HTML server within the network of the hospital. A second firewall is installed between the gateway and the external users and builds up a virtual private network (VPN). A connection between the gateway and the external user is only acknowledged if the computers involved authenticate each other via certificates and the external users authenticate via a multi-stage password system. All data are transferred encrypted. External users get only access to images that have been renamed to a pseudonym by means of automated processing before. With an ADSL internet access, external users achieve an image load frequency of 0.4 CT images per second. More than 90 % of the delay during image transfer results from security checks within the firewalls. Data passing the gateway induce no measurable delay. Project goals were realized by means of an infrastructure that works vendor independently with any HTML-based image distribution systems. The requirements of data security were realized using state-of-the-art web techniques. Adequate access and transfer speed lead to a widespread acceptance of the system on the part of external users.

  12. Telnet Cornucopia: Interactive Access to Information Resource Collections.

    ERIC Educational Resources Information Center

    Harris, Judi

    1992-01-01

    Describes various resources accessed through Telnet software that are available through the Internet for use in elementary and secondary education. Highlights include the National Public Telecomputing Network's Cleveland Freenet; Washington University's SERVICES gateway; and Wide Area Information Server (WAIS) programs. (LRW)

  13. A Practical Evaluation of a High-Security Energy-Efficient Gateway for IoT Fog Computing Applications

    PubMed Central

    Castedo, Luis

    2017-01-01

    Fog computing extends cloud computing to the edge of a network enabling new Internet of Things (IoT) applications and services, which may involve critical data that require privacy and security. In an IoT fog computing system, three elements can be distinguished: IoT nodes that collect data, the cloud, and interconnected IoT gateways that exchange messages with the IoT nodes and with the cloud. This article focuses on securing IoT gateways, which are assumed to be constrained in terms of computational resources, but that are able to offload some processing from the cloud and to reduce the latency in the responses to the IoT nodes. However, it is usually taken for granted that IoT gateways have direct access to the electrical grid, which is not always the case: in mission-critical applications like natural disaster relief or environmental monitoring, it is common to deploy IoT nodes and gateways in large areas where electricity comes from solar or wind energy that charge the batteries that power every device. In this article, how to secure IoT gateway communications while minimizing power consumption is analyzed. The throughput and power consumption of Rivest–Shamir–Adleman (RSA) and Elliptic Curve Cryptography (ECC) are considered, since they are really popular, but have not been thoroughly analyzed when applied to IoT scenarios. Moreover, the most widespread Transport Layer Security (TLS) cipher suites use RSA as the main public key-exchange algorithm, but the key sizes needed are not practical for most IoT devices and cannot be scaled to high security levels. In contrast, ECC represents a much lighter and scalable alternative. Thus, RSA and ECC are compared for equivalent security levels, and power consumption and data throughput are measured using a testbed of IoT gateways. The measurements obtained indicate that, in the specific fog computing scenario proposed, ECC is clearly a much better alternative than RSA, obtaining energy consumption reductions of up

  14. A Practical Evaluation of a High-Security Energy-Efficient Gateway for IoT Fog Computing Applications.

    PubMed

    Suárez-Albela, Manuel; Fernández-Caramés, Tiago M; Fraga-Lamas, Paula; Castedo, Luis

    2017-08-29

    Fog computing extends cloud computing to the edge of a network enabling new Internet of Things (IoT) applications and services, which may involve critical data that require privacy and security. In an IoT fog computing system, three elements can be distinguished: IoT nodes that collect data, the cloud, and interconnected IoT gateways that exchange messages with the IoT nodes and with the cloud. This article focuses on securing IoT gateways, which are assumed to be constrained in terms of computational resources, but that are able to offload some processing from the cloud and to reduce the latency in the responses to the IoT nodes. However, it is usually taken for granted that IoT gateways have direct access to the electrical grid, which is not always the case: in mission-critical applications like natural disaster relief or environmental monitoring, it is common to deploy IoT nodes and gateways in large areas where electricity comes from solar or wind energy that charge the batteries that power every device. In this article, how to secure IoT gateway communications while minimizing power consumption is analyzed. The throughput and power consumption of Rivest-Shamir-Adleman (RSA) and Elliptic Curve Cryptography (ECC) are considered, since they are really popular, but have not been thoroughly analyzed when applied to IoT scenarios. Moreover, the most widespread Transport Layer Security (TLS) cipher suites use RSA as the main public key-exchange algorithm, but the key sizes needed are not practical for most IoT devices and cannot be scaled to high security levels. In contrast, ECC represents a much lighter and scalable alternative. Thus, RSA and ECC are compared for equivalent security levels, and power consumption and data throughput are measured using a testbed of IoT gateways. The measurements obtained indicate that, in the specific fog computing scenario proposed, ECC is clearly a much better alternative than RSA, obtaining energy consumption reductions of up to

  15. Communication-Gateway Software For NETEX, DECnet, And TCP/IP

    NASA Technical Reports Server (NTRS)

    Keith, B.; Ferry, D.; Fendler, E.

    1990-01-01

    Communications gateway software, GATEWAY, provides process-to-process communication between remote applications programs in different protocol domains. Communicating peer processes may be resident on any paired combination of NETEX, DECnet, or TCP/IP hosts. Provides necessary mapping from one protocol to another and facilitates practical intermachine communications in cost-effective manner by eliminating need to standardize on single protocol or to implement multiple protocols in host computers. Written in Ada.

  16. Matroshka AstroRad Radiation Experiment (MARE) on the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Gaza, R.; Hussein, H.; Murrow, D.; Hopkins, J.; Waterman, G.; Milstein, O.; Berger, T.; Przybyla, B.; Aeckerlein, J.; Marsalek, K.; Matthiae, D.; Rutczynska, A.

    2018-02-01

    The Matroshka AstroRad Radiation Experiment is a science payload on Orion EM-1 flight. A research platform derived from MARE is proposed for the Deep Space Gateway. Feedback is invited on desired Deep Space Gateway design features to maximize its science potential.

  17. An Interactive, Integrated, Instructional Pathway to the LEAD Science Gateway

    NASA Astrophysics Data System (ADS)

    Yalda, S.; Clark, R.; Davis, L.; Wiziecki, E. N.

    2008-12-01

    Linked Environments for Atmospheric Discovery (LEAD) is a bold and revolutionary paradigm that through a Web-based Service Oriented Architecture (SOA) exposes the user to a rich environment of data, models, data mining and visualization and analysis tools, enabling the user to ask science questions of applications while the complexity of the software and middleware managing these applications is hidden from the user. From its inception in 2003, LEAD has championed goals that have context for the future of weather and related research and education. LEAD espouses to lowering the barrier for using complex end-to-end weather technologies by a) democratizing the availability of advanced weather technologies, b) empowering the user of these technologies to tackle a variety of problems, and c) facilitating learning and understanding. LEAD, as it exists today, is poised to enable a diverse community of scientists, educators, students, and operational practitioners. The project has been informed by atmospheric and computer scientists, educators, and educational consultants who, in search of new knowledge, understanding, ideas, and learning methodologies, seek easy access to new capabilities that allow for user-directed and interactive query and acquisition, simulation, assimilation, data mining, computational modeling, and visualization. As one component of the total LEAD effort, the LEAD education team has designed interactive, integrated, instructional pathways within a set of learning modules (LEAD-to-Learn) to facilitate, enhance, and enable the use of the LEAD gateway in the classroom. The LEAD education initiative focuses on the means to integrate data, tools, and services used by researchers into undergraduate meteorology education in order to provide an authentic and contextualized environment for teaching and learning. Educators, educational specialists, and students from meteorology and computer science backgrounds have collaborated on the design and development

  18. Research Possibilities Beyond Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Smitherman, D. V.; Needham, D. H.; Lewis, R.

    2018-02-01

    This abstract explores the possibilities for a large research facilities module attached to the Deep Space Gateway, using the same large module design and basic layout planned for the Deep Space Transport.

  19. A Dual-Process Discrete-Time Survival Analysis Model: Application to the Gateway Drug Hypothesis

    ERIC Educational Resources Information Center

    Malone, Patrick S.; Lamis, Dorian A.; Masyn, Katherine E.; Northrup, Thomas F.

    2010-01-01

    The gateway drug model is a popular conceptualization of a progression most substance users are hypothesized to follow as they try different legal and illegal drugs. Most forms of the gateway hypothesis are that "softer" drugs lead to "harder," illicit drugs. However, the gateway hypothesis has been notably difficult to…

  20. Optimization Shield Materials Trade Study for Lunar/Gateway Mission

    NASA Technical Reports Server (NTRS)

    Tripathi, R. K.; Wilson, J. W.; Cucinotta, F. A.; Anderson, B. M.; Simonsen, L. C.

    2002-01-01

    The great cost of added radiation shielding is a potential limiting factor in many deep space missions. For this enabling technology, we are developing tools for optimized shield design over multi-segmented missions involving multiple work and living areas in the transport and duty phase of various space missions. The total shield mass over all pieces of equipment and habitats is optimized subject to career dose and dose rate constraints. Preliminary studies of deep space missions indicate that for long duration space missions, improved shield materials will be required. The details of this new method and its impact on space missions and other technologies will be discussed. This study will provide a vital tool for evaluating Gateway designs in their usage context. Providing protection against the hazards of space radiation is one of the challenges to the Gateway infrastructure designs. We will use the mission optimization software to scope the impact of Gateway operations on human exposures and the effectiveness of alternate shielding materials on Gateway infrastructure designs. It is being proposed to use Moon and the Lagrange points as the hub for deep space missions. This study will provide a guide to the effectiveness of multifunctional materials in preparation to more detailed geometry studies in progress.

  1. US Gateway to SIMBAD Astronomical Database

    NASA Technical Reports Server (NTRS)

    Eichhorn, G.; Oliversen, R. (Technical Monitor)

    1999-01-01

    During the last year the US SIMBAD Gateway Project continued to provide services like user registration to the US users of the SIMBAD database in France. Currently there are over 3400 US users registered. We also provide user support by answering questions from users and handling requests for lost passwords when still necessary. We have implemented in cooperation with the CDS SIMBAD project access to the SIMBAD database for US users on an Internet address basis. This allows most US users to access SIMBAD without having to enter passwords. We have maintained the mirror copy of the SIMBAD database on a server at SAO. This has allowed much faster access for the US users. We also supported a demonstration of the SIMBAD database at the meeting of the American Astronomical Society in January. We shipped computer equipment to the meeting and provided support for the demonstration activities at the SIMBAD booth. We continued to improve the cross-linking between the SIMBAD project and the Astrophysics Data System. This cross-linking between these systems is very much appreciated by the users of both the SIMBAD database and the ADS Abstract Service. The mirror of the SIMBAD database at SAO makes this connection faster for the US astronomers. We exchange information between the ADS and SIMBAD on a daily basis. The close cooperation between the CDS in Strasbourg and SAO, facilitated by this project, is an important part of the astronomy-wide digital library initiative called Urania. It has proven to be a model in how different data centers can collaborate and enhance the value of their products by linking with other data centers.

  2. Wireless Internet Gateways (WINGS)

    DTIC Science & Technology

    1997-01-01

    WIRELESS INTERNET GATEWAYS (WINGS) J.J. Garcia-Luna-Aceves, Chane L. Fullmer, Ewerton Madruga Computer Engineering Department University of...rooftop.com Abstract— Today’s internetwork technology has been extremely success- ful in linking huge numbers of computers and users. However, to date...this technology has been oriented to computer interconnection in relatively stable operational environments, and thus cannot adequately support many of

  3. Copyright, Licensing Agreements and Gateways.

    ERIC Educational Resources Information Center

    Elias, Arthur W.

    1990-01-01

    Discusses technological developments in information distribution and management in relation to concepts of ownership. A historical overview of the concept of copyright is presented; licensing elements for databases are examined; and implications for gateway systems are explored, including ownership, identification of users, and allowable uses of…

  4. Expanding the chemical information science gateway.

    PubMed

    Bajorath, Jürgen

    2017-01-01

    Broadly defined, chemical information science (CIS) covers chemical structure and data analysis including biological activity data as well as processing, organization, and retrieval of any form of chemical information. The CIS Gateway (CISG) of F1000Research was created to communicate research involving the entire spectrum of chemical information, including chem(o)informatics. CISG provides a forum for high-quality publications and a meaningful alternative to conventional journals. This gateway is supported by leading experts in the field recognizing the need for open science and a flexible publication platform enabling off-the-beaten path contributions. This editorial aims to further rationalize the scope of CISG, position it within its scientific environment, and open it up to a wider audience. Chemical information science is an interdisciplinary field with high potential to interface with experimental work.

  5. Patents or patients? Global access to pharmaceuticals and social justice.

    PubMed

    de Wildt, Gilles; Khoon, Chan Chee

    2008-01-01

    Innovation, vaccine development, and world-wide equitable access to necessary pharmaceuticals are hindered by current patenting arrangements and the orientation of pharmaceutical research. Plausible alternatives exist, including instituting the right of national or international agencies to act in the public interest and to buy patents selectively with a view to innovation and equitable access. Alternatives could partly or wholly finance themselves and lower pharmaceutical prices globally. Countries, individuals or groups of patients could help promote alternatives by calling into question the current emphasis on commercialization and profit, and by demanding globally equitable arrangements when sharing data that are important for research or when individuals or communities volunteer as research participants.

  6. GATEWAY Report Brief: SSL Demonstration: Long-Term Evaluation of Indoor Field Performance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    Report brief summarizing a GATEWAY program evaluation of the long-term performance characteristics (chromaticity change, maintained illuminance, and operations and maintenance) of LED lighting systems in four field installations previously documented in separate DOE GATEWAY reports.

  7. XDS-I Gateway Development for HIE Connectivity with Legacy PACS at Gil Hospital.

    PubMed

    Simalango, Mikael Fernandus; Kim, Youngchul; Seo, Young Tae; Choi, Young Hwan; Cho, Yong Kyun

    2013-12-01

    The ability to support healthcare document sharing is imperative in a health information exchange (HIE). Sharing imaging documents or images, however, can be challenging, especially when they are stored in a picture archiving and communication system (PACS) archive that does not support document sharing via standard HIE protocols. This research proposes a standard-compliant imaging gateway that enables connectivity between a legacy PACS and the entire HIE. Investigation of the PACS solutions used at Gil Hospital was conducted. An imaging gateway application was then developed using a Java technology stack. Imaging document sharing capability enabled by the gateway was tested by integrating it into Gil Hospital's order communication system and its HIE infrastructure. The gateway can acquire radiology images from a PACS storage system, provide and register the images to Gil Hospital's HIE for document sharing purposes, and make the images retrievable by a cross-enterprise document sharing document viewer. Development of an imaging gateway that mediates communication between a PACS and an HIE can be considered a viable option when the PACS does not support the standard protocol for cross-enterprise document sharing for imaging. Furthermore, the availability of common HIE standards expedites the development and integration of the imaging gateway with an HIE.

  8. XDS-I Gateway Development for HIE Connectivity with Legacy PACS at Gil Hospital

    PubMed Central

    Simalango, Mikael Fernandus; Kim, Youngchul; Seo, Young Tae; Cho, Yong Kyun

    2013-01-01

    Objectives The ability to support healthcare document sharing is imperative in a health information exchange (HIE). Sharing imaging documents or images, however, can be challenging, especially when they are stored in a picture archiving and communication system (PACS) archive that does not support document sharing via standard HIE protocols. This research proposes a standard-compliant imaging gateway that enables connectivity between a legacy PACS and the entire HIE. Methods Investigation of the PACS solutions used at Gil Hospital was conducted. An imaging gateway application was then developed using a Java technology stack. Imaging document sharing capability enabled by the gateway was tested by integrating it into Gil Hospital's order communication system and its HIE infrastructure. Results The gateway can acquire radiology images from a PACS storage system, provide and register the images to Gil Hospital's HIE for document sharing purposes, and make the images retrievable by a cross-enterprise document sharing document viewer. Conclusions Development of an imaging gateway that mediates communication between a PACS and an HIE can be considered a viable option when the PACS does not support the standard protocol for cross-enterprise document sharing for imaging. Furthermore, the availability of common HIE standards expedites the development and integration of the imaging gateway with an HIE. PMID:24523994

  9. The Globus Galaxies Platform. Delivering Science Gateways as a Service

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madduri, Ravi; Chard, Kyle; Chard, Ryan

    We use public cloud computers to host sophisticated scientific data; software is then used to transform scientific practice by enabling broad access to capabilities previously available only to the few. The primary obstacle to more widespread use of public clouds to host scientific software (‘cloud-based science gateways’) has thus far been the considerable gap between the specialized needs of science applications and the capabilities provided by cloud infrastructures. We describe here a domain-independent, cloud-based science gateway platform, the Globus Galaxies platform, which overcomes this gap by providing a set of hosted services that directly address the needs of science gatewaymore » developers. The design and implementation of this platform leverages our several years of experience with Globus Genomics, a cloud-based science gateway that has served more than 200 genomics researchers across 30 institutions. Building on that foundation, we have also implemented a platform that leverages the popular Galaxy system for application hosting and workflow execution; Globus services for data transfer, user and group management, and authentication; and a cost-aware elastic provisioning model specialized for public cloud resources. We describe here the capabilities and architecture of this platform, present six scientific domains in which we have successfully applied it, report on user experiences, and analyze the economics of our deployments. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.« less

  10. Evaluation of R1-6 gateway treatment alternatives for pedestrian crossings.

    DOT National Transportation Integrated Search

    2016-02-01

    A series of studies evaluated the Gateway configuration of R1-6 in-street signs. A : Gateway configuration consists of an R1-6 sign on the centerline, an R1-6 signs on both edges of : the roadway, and R1-6 signs on the lane lines if it is a multilane...

  11. Expanding the chemical information science gateway

    PubMed Central

    Bajorath, Jürgen

    2017-01-01

    Broadly defined, chemical information science (CIS) covers chemical structure and data analysis including biological activity data as well as processing, organization, and retrieval of any form of chemical information. The CIS Gateway (CISG) of F1000Research was created to communicate research involving the entire spectrum of chemical information, including chem(o)informatics. CISG provides a forum for high-quality publications and a meaningful alternative to conventional journals. This gateway is supported by leading experts in the field recognizing the need for open science and a flexible publication platform enabling off-the-beaten path contributions. This editorial aims to further rationalize the scope of CISG, position it within its scientific environment, and open it up to a wider audience. Chemical information science is an interdisciplinary field with high potential to interface with experimental work. PMID:29043072

  12. High-performance parallel interface to synchronous optical network gateway

    DOEpatents

    St. John, Wallace B.; DuBois, David H.

    1998-08-11

    A digital system provides sending and receiving gateways for HIPPI interfaces. Electronic logic circuitry formats data signals and overhead signals in a data frame that is suitable for transmission over a connecting fiber optic link. Multiplexers route the data and overhead signals to a framer module. The framer module allocates the data and overhead signals to a plurality of 9-byte words that are arranged in a selected protocol. The formatted words are stored in a storage register for output through the gateway.

  13. Belonging: The Gateway to Global Learning for All Students

    ERIC Educational Resources Information Center

    Braskamp, David C.; Braskamp, Larry A.; Glass, Chris R.

    2015-01-01

    For several years, the authors have been analyzing data from the Global Perspective Inventory (GPI), a national survey that measures undergraduate students' ability to take a global perspective by examining cognitive, intrapersonal, and interpersonal dimensions of this key attribute of global learning. The survey also probes the frequency of…

  14. A Remote Health Monitoring System for the Elderly Based on Smart Home Gateway

    PubMed Central

    Shao, Minggang

    2017-01-01

    This paper proposed a remote health monitoring system for the elderly based on smart home gateway. The proposed system consists of three parts: the smart clothing, the smart home gateway, and the health care server. The smart clothing collects the elderly's electrocardiogram (ECG) and motion signals. The home gateway is used for data transmission. The health care server provides services of data storage and user information management; it is constructed on the Windows-Apache-MySQL-PHP (WAMP) platform and is tested on the Ali Cloud platform. To resolve the issues of data overload and network congestion of the home gateway, an ECG compression algorithm is applied. System demonstration shows that the ECG signals and motion signals of the elderly can be monitored. Evaluation of the compression algorithm shows that it has a high compression ratio and low distortion and consumes little time, which is suitable for home gateways. The proposed system has good scalability, and it is simple to operate. It has the potential to provide long-term and continuous home health monitoring services for the elderly. PMID:29204258

  15. A Remote Health Monitoring System for the Elderly Based on Smart Home Gateway.

    PubMed

    Guan, Kai; Shao, Minggang; Wu, Shuicai

    2017-01-01

    This paper proposed a remote health monitoring system for the elderly based on smart home gateway. The proposed system consists of three parts: the smart clothing, the smart home gateway, and the health care server. The smart clothing collects the elderly's electrocardiogram (ECG) and motion signals. The home gateway is used for data transmission. The health care server provides services of data storage and user information management; it is constructed on the Windows-Apache-MySQL-PHP (WAMP) platform and is tested on the Ali Cloud platform. To resolve the issues of data overload and network congestion of the home gateway, an ECG compression algorithm is applied. System demonstration shows that the ECG signals and motion signals of the elderly can be monitored. Evaluation of the compression algorithm shows that it has a high compression ratio and low distortion and consumes little time, which is suitable for home gateways. The proposed system has good scalability, and it is simple to operate. It has the potential to provide long-term and continuous home health monitoring services for the elderly.

  16. GATEWAY Demonstrations: Long-Term Evaluation of SSL Field Performance in Select Interior Projects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, Tess E.; Davis, Robert G.; Wilkerson, Andrea M.

    The GATEWAY program evaluated the long-term performance characteristics (chromaticity change, maintained illuminance, and operations and maintenance) of LED lighting systems in four field installations previously documented in separate DOE GATEWAY reports.

  17. Exploiting Multisite Gateway and pENFRUIT plasmid collection for fruit genetic engineering.

    PubMed

    Estornell, Leandro H; Granell, Antonio; Orzaez, Diego

    2012-01-01

    MultiSite Gateway cloning techniques based on homologous recombination facilitate the combinatorial assembly of basic genetic pieces (i.e., promoters, CDS, and terminators) into gene expression or gene silencing cassettes. pENFRUIT is a collection of MultiSite Triple Gateway Entry vectors dedicated to genetic engineering in fruits. It comprises a number of fruit-operating promoters as well as C-terminal tags adapted to the Gateway standard. In this way, flanking regulatory/labeling sequences can be easily Gateway-assembled with a given gene of interest for its ectopic expression or silencing in fruits. The resulting gene constructs can be analyzed in stable transgenic plants or in transient expression assays, the latter allowing fast testing of the increasing number of combinations arising from MultiSite methodology. A detailed description of the use of MultiSite cloning methodology for the assembly of pENFRUIT elements is presented.

  18. Expansion of the Gateway MultiSite Recombination Cloning Toolkit

    PubMed Central

    Shearin, Harold K.; Dvarishkis, Alisa R.; Kozeluh, Craig D.; Stowers, R. Steven

    2013-01-01

    Precise manipulation of transgene expression in genetic model organisms has led to advances in understanding fundamental mechanisms of development, physiology, and genetic disease. Transgene construction is, however, a precondition of transgene expression, and often limits the rate of experimental progress. Here we report an expansion of the modular Gateway MultiSite recombination-cloning platform for high efficiency transgene assembly. The expansion includes two additional destination vectors and entry clones for the LexA binary transcription system, among others. These new tools enhance the expression levels possible with Gateway MultiSite generated transgenes and make possible the generation of LexA drivers and reporters with Gateway MultiSite cloning. In vivo data from transgenic Drosophila functionally validating each novel component are presented and include neuronal LexA drivers, LexAop2 red and green fluorescent synaptic vesicle reporters, TDC2 and TRH LexA, GAL4, and QF drivers, and LexAop2, UAS, and QUAS channelrhodopsin2 T159C reporters. PMID:24204935

  19. US Gateway to SIMBAD Astronomical Database

    NASA Technical Reports Server (NTRS)

    Eichhorn, G.

    1998-01-01

    During the last year the US SIMBAD Gateway Project continued to provide services like user registration to the US users of the SIMBAD database in France. User registration is required by the SIMBAD project in France. Currently, there are almost 3000 US users registered. We also provide user support by answering questions from users and handling requests for lost passwords. We have worked with the CDS SIMBAD project to provide access to the SIMBAD database to US users on an Internet address basis. This will allow most US users to access SIMBAD without having to enter passwords. This new system was installed in August, 1998. The SIMBAD mirror database at SAO is fully operational. We worked with the CDS to adapt it to our computer system. We implemented automatic updating procedures that update the database and password files daily. This mirror database provides much better access to the US astronomical community. We also supported a demonstration of the SIMBAD database at the meeting of the American Astronomical Society in January. We shipped computer equipment to the meeting and provided support for the demonstration activities at the SIMBAD booth. We continued to improve the cross-linking between the SIMBAD project and the Astro- physics Data System. This cross-linking between these systems is very much appreciated by the users of both the SIMBAD database and the ADS Abstract Service. The mirror of the SIMBAD database at SAO makes this connection faster for the US astronomers. The close cooperation between the CDS in Strasbourg and SAO, facilitated by this project, is an important part of the astronomy-wide digital library initiative called Urania. It has proven to be a model in how different data centers can collaborate and enhance the value of their products by linking with other data centers.

  20. Design of an MSAT-X mobile transceiver and related base and gateway stations

    NASA Technical Reports Server (NTRS)

    Fang, Russell J. F.; Bhaskar, Udaya; Hemmati, Farhad; Mackenthun, Kenneth M.; Shenoy, Ajit

    1987-01-01

    This paper summarizes the results of a design study of the mobile transceiver, base station, and gateway station for NASA's proposed Mobile Satellite Experiment (MSAT-X). Major ground segment system design issues such as frequency stability control, modulation method, linear predictive coding vocoder algorithm, and error control technique are addressed. The modular and flexible transceiver design is described in detail, including the core, RF/IF, modem, vocoder, forward error correction codec, amplitude-companded single sideband, and input/output modules, as well as the flexible interface. Designs for a three-carrier base station and a 10-carrier gateway station are also discussed, including the interface with the controllers and with the public-switched telephone networks at the gateway station. Functional specifications are given for the transceiver, the base station, and the gateway station.

  1. Design of an MSAT-X mobile transceiver and related base and gateway stations

    NASA Astrophysics Data System (ADS)

    Fang, Russell J. F.; Bhaskar, Udaya; Hemmati, Farhad; Mackenthun, Kenneth M.; Shenoy, Ajit

    This paper summarizes the results of a design study of the mobile transceiver, base station, and gateway station for NASA's proposed Mobile Satellite Experiment (MSAT-X). Major ground segment system design issues such as frequency stability control, modulation method, linear predictive coding vocoder algorithm, and error control technique are addressed. The modular and flexible transceiver design is described in detail, including the core, RF/IF, modem, vocoder, forward error correction codec, amplitude-companded single sideband, and input/output modules, as well as the flexible interface. Designs for a three-carrier base station and a 10-carrier gateway station are also discussed, including the interface with the controllers and with the public-switched telephone networks at the gateway station. Functional specifications are given for the transceiver, the base station, and the gateway station.

  2. Sandy Hook : alternative access concept plan and vehicle replacement study

    DOT National Transportation Integrated Search

    2009-06-01

    This study addresses two critical issues of concern to the Sandy Hook Unit of Gateway National : Recreational Area: (1) options for alternative access to Sandy Hook during peak summer season, : particularly when the park is closed to private vehicles...

  3. Earth Observing System Data Gateway

    NASA Technical Reports Server (NTRS)

    Pfister, Robin; McMahon, Joe; Amrhein, James; Sefert, Ed; Marsans, Lorena; Solomon, Mark; Nestler, Mark

    2006-01-01

    The Earth Observing System Data Gateway (EDG) software provides a "one-stop-shopping" standard interface for exploring and ordering Earth-science data stored at geographically distributed sites. EDG enables a user to do the following: 1) Search for data according to high-level criteria (e.g., geographic location, time, or satellite that acquired the data); 2) Browse the results of a search, viewing thumbnail sketches of data that satisfy the user s criteria; and 3) Order selected data for delivery to a specified address on a chosen medium (e.g., compact disk or magnetic tape). EDG consists of (1) a component that implements a high-level client/server protocol, and (2) a collection of C-language libraries that implement the passing of protocol messages between an EDG client and one or more EDG servers. EDG servers are located at sites usually called "Distributed Active Archive Centers" (DAACs). Each DAAC may allow access to many individual data items, called "granules" (e.g., single Landsat images). Related granules are grouped into collections called "data sets." EDG enables a user to send a search query to multiple DAACs simultaneously, inspect the resulting information, select browseable granules, and then order selected data from the different sites in a seamless fashion.

  4. Fostering Evidence-Informed Teaching in Crucial Classes: Faculty Development in Gateway Courses

    ERIC Educational Resources Information Center

    McGowan, Susannah; Felten, Peter; Caulkins, Joshua; Artze-Vega, Isis

    2017-01-01

    Faculty and faculty developers can improve student learning and outcomes in gateway courses by improving course design, integrating active learning, and aligning assessments with course goals. Drawing on the authors' varied experiences and a large national initiative, this chapter outlines challenges and strategies to support gateway-course…

  5. ADDOSS: Autonomously Deployed Deep-ocean Seismic System - Communications Gateway for Ocean Observatories

    NASA Astrophysics Data System (ADS)

    Laske, Gabi; Berger, Jon; Orcutt, John; Babcock, Jeff

    2014-05-01

    We describe an autonomously deployable, communications gateway designed to provide long-term and near real-time data from ocean observatories. The key features of this new system are its abilities to telemeter sensor data from the seafloor to shore without cables or moorings, and to be deployed without a ship, thereby greatly reducing life-cycle costs. The free-floating surface communications gateway utilizes a Liquid Robotics wave glider comprising a surfboard-sized float towed by a tethered, submerged glider, which converts wave motion into thrust. For navigation, the wave glider is equipped with a small computer, a GPS receiver, a rudder, solar panels and batteries, and an Iridium satellite modem. Acoustic communications connect the subsea instruments and the surface gateway while communications between the gateway and land are provided by the Iridium satellite constellation. Wave gliders have demonstrated trans-oceanic range and long-term station keeping capabilities. The acoustics communications package is mounted in a shallow tow body which utilizes a WHOI micro modem and a Benthos low frequency, directional transducer. A matching modem and transducer is mounted on the ocean bottom package. Tests of the surface gateway in 4350 m of water demonstrated an acoustic efficiency of approximately 396 bits/J. For example, it has the ability to send 4 channels of compressed, 1 sample per second data from the ocean bottom to the gateway with an average power draw of approximately 0.15 W and a latency of less than 3 minutes. This gateway is used to send near real-time data from a broadband ocean bottom seismic observatory, first during short week-to-months long test deployments but will ultimately be designed for a two-year operational life. Such data from presently unobserved oceanic areas are critical for both national and international agencies in monitoring and characterizing earthquakes, tsunamis, and nuclear explosions. We present initial results from a two short

  6. Breakthrough Science Enabled by Regular Access to Orbits Beyond Earth

    NASA Astrophysics Data System (ADS)

    Gorjian, V.

    2018-02-01

    Regular launches to the Deep Space Gateway (DSG) will enable smallsats to access orbits not currently easily available to low cost missions. These orbits will allow great new science, especially when using the DSG as an optical hub for downlink.

  7. America's freight transportation gateways : connecting our nation to places and markets abroad : [2004

    DOT National Transportation Integrated Search

    2004-01-01

    Transportation gateways - seaports, airports, and land border crossings - are the entry and exit points for international merchandise trade between the United States and countries around the world. During the past decade, the leading U.S. gateways ha...

  8. The Design of Passive Optical Networking+Ethernet over Coaxial Cable Access Networking and Video-on-Demand Services Carrying

    NASA Astrophysics Data System (ADS)

    Ji, Wei

    2013-07-01

    Video on demand is a very attractive service used for entertainment, education, and other purposes. The design of passive optical networking+Ethernet over coaxial cable accessing and a home gateway system is proposed. The network integrates the passive optical networking and Ethernet over coaxial cable to provide high dedicated bandwidth for the metropolitan video-on-demand services. Using digital video broadcasting, IP television protocol, unicasting, and broadcasting mechanisms maximizes the system throughput. The home gateway finishes radio frequency signal receiving and provides three kinds of interfaces for high-definition video, voice, and data, which achieves triple-play and wire/wireless access synchronously.

  9. Space Station Freedom Gateway to the Future

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The first inhabited outpost on the frontier of space will be a place to live, work, and discover. Experiments conducted on Freedom will advance scientific knowledge about our world, our environment, and ourselves. We will learn how to adapt to the space environment and to build and operate new spacecraft with destinations far beyond Earth, continuing the tradition of exploration that began with a journey to the Moon. What we learn from living and working on Freedom will strengthen our expertise in science and engineering, promote national research and development initiatives and inspire another generation of Americans to push forward and onward. On the eve of the 21st century, Space Station Freedom will be our gateway to the future. This material covers gateways to space, research, discovery, utilization, benefits, and NASA.

  10. Internet-to-orbit gateway and virtual ground station: A tool for space research and scientific outreach

    NASA Astrophysics Data System (ADS)

    Jaffer, Ghulam; Nader, Ronnie; Koudelka, Otto

    2011-09-01

    Students in higher education, and scientific and technological researchers want to communicate with the International Space Station (ISS), download live satellite images, and receive telemetry, housekeeping and science/engineering data from nano-satellites and larger spacecrafts. To meet this need the Ecuadorian Civilian Space Agency (EXA) has recently provided the civilian world with an internet-to-orbit gateway (Hermes-A/Minotaur) Space Flight Control Center (SFCC) available for public use. The gateway has a maximum range of tracking and detection of 22,000 km and sensitivity such that it can receive and discriminate the signals from a satellite transmitter with power˜0.1 W. The capability is enough to receive the faintest low-earth-orbit (LEO) satellites. This gateway virtually connects participating internet clients around the world to a remote satellite ground station (GS), providing a broad community for multinational cooperation. The goal of the GS is to lower financial and engineering barriers that hinder access to science and engineering data from orbit. The basic design of the virtual GS on a user side is based on free software suites. Using these and other software tools the GS is able to provide access to orbit for a multitude of users without each having to go through the costly setups. We present the design and implementation of the virtual GS in a higher education and scientific outreach settings. We also discuss the basic architecture of the single existing system and the benefits of a proposed distributed system. Details of the software tools and their applicability to synchronous round-the-world tracking, monitoring and processing performed by students and teams at Graz University of Technology, Austria, EXA-Ecuador, University of Michigan, USA and JAXA who have participated in various mission operations and have investigated real-time satellite data download and image acquisition and processing. Students and other remote users at these

  11. Strengthening global vaccine access for adolescents and adults.

    PubMed

    Nanni, Angeline; Meredith, Stefanie; Gati, Stephanie; Holm, Karin; Harmon, Tom; Ginsberg, Ann

    2017-12-14

    Global immunization efforts to date have heavily focused on infants and children, with noted success on public health. Healthy adolescents and adults contribute to the economic growth and development of countries but efforts to ensure vaccine coverage for these groups receive inadequate global attention and resources. Emerging epidemics for a number of infectious diseases including Ebola, Zika, dengue, malaria and the continuing epidemics of tuberculosis and several sexually transmitted infections, including HIV, HPV and Hepatitis B, have high incidence and prevalence in adolescents and adults. New vaccines under development for these diseases and under-used vaccines such as for human papilloma virus will have the greatest health and economic impact in these populations. Global consensus, political will, policies, global and country infrastructure, and financing mechanisms are needed to accelerate access for the billions of adolescents and adults living under the threat of devastating infectious disease outbreaks and epidemics, especially in lower income countries. The global health community and countries cannot afford to delay planning for implementation of adolescent and adult vaccine programs that will potentially save millions of lives and strengthen global and national economies. The article examines this next challenge and suggests a research agenda and a framework for action to galvanize global and national policy decision-makers to begin preparations for future immunization challenges. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Resources in the VLab Science Gateway: Online applications for thermodynamics and thermal elastic properties of mantle minerals

    NASA Astrophysics Data System (ADS)

    Wentzcovitch, R. M.; Da Silveira, P. R.; Wu, Z.; Yu, Y.

    2013-12-01

    Today first principles calculations in mineral physics play a fundamental role in understanding of the Earth. They complement experiments by expanding the pressure and temperature range for which properties can be obtained and provide access to atomic scale phenomena. Since the wealth of predictive first principles results can hardly be communicated in printed form, we have developed online applications where published results can be reproduced/verified online and extensive unpublished results can be generated in customized form. So far these applications have included thermodynamics properties of end-member phases and thermal elastic properties of end-member phases and few solid solutions. Extension of this software infrastructure to include other properties is in principle straightforward. This contribution will review the nature of results that can be generated (methods, thermodynamics domain, list of minerals, properties, etc) and nature of the software infrastructure. These applications are part of a more extensive cyber-infrastructure operating in the XSEDE - the VLab Science Gateway [1]. [1] https://www.xsede.org/web/guest/gateways-listing Research supported by NSF grants ATM-0428744 and EAR-1047629.

  13. Gateway integrated transportation in strategy and implementation

    DOT National Transportation Integrated Search

    2004-03-01

    Building on the 2001 Waterborne Transportation Study, which summarized the results of Gateways Phase I ferry-expansion effort, this report analyses several ferry landing sights in terms of their potential for expansion. The report looks at watersi...

  14. Design and implementation of Skype USB user gateway software

    NASA Astrophysics Data System (ADS)

    Qi, Yang

    2017-08-01

    With the widespread application of VoIP, the client with private protocol becomes more and more popular. Skype is one of the representatives. How to connect Skype with PSTN just by Skype client has gradually become hot. This paper design and implement the software based on a kind of USB User Gateway. With the software Skype user can freely communicate with PSTN phone. FSM is designed as the core of the software, and Skype control is separated by the USB Gateway control. In this way, the communication becomes more flexible and efficient. In the actual user testing, the software obtains good results.

  15. Chief Academic Officers and Gateway Courses: Keys to Institutional Retention and Persistence Agendas

    ERIC Educational Resources Information Center

    Matthews, Roberta S.; Newman, Scott

    2017-01-01

    Among persistence and retention agenda initiatives undertaken by colleges and universities, gateway-course improvement efforts are often overlooked. However, the engagement of diverse institutional stakeholders in the transformation of gateway courses can contribute significantly to student success. Chief academic officers are in a unique position…

  16. Global Access-controlled Transfer e-frame (GATe)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2012-05-30

    Global Access-controlled Transfer e-frame (GATe) was designed to take advantage of the patterns that occur during an electronic record transfer process. The e-frame (or electronic framework or platform) is the foundation for developing secure information transfer to meet classified and unclassified business processes and is particularly useful when there is a need to share information with various entities in a controlled and secure environment. It can share, search, upload, download and retrieve sensitive information, as well as provides reporting capabilities.

  17. Globalization of Access to Higher Education: Lessons for Nigeria

    ERIC Educational Resources Information Center

    Uchendu, C. C.

    2013-01-01

    Education is such a powerful instrument for national transformation and development such that anything that affects an educational system negatively affects the national development. This study investigated the extent to which access to higher education is globalized and the implications for Nigeria. An ex-post facto research design was adopted…

  18. Gateway's Horizon: A Center of Excellence

    ERIC Educational Resources Information Center

    Herring, Jayne; Colony, Lee

    2007-01-01

    This article describes Gateway Technical College's Horizon Center for Transportation Technology, located in Kenosha, Wisconsin, which was the product of collaboration with business and industry, community support and a U.S. Department of Labor (DOL) grant. The center, which opened this fall, is a prime example of a sustainable community…

  19. Middle Miocene paleoenvironmental crises in Central Eurasia caused by changes in marine gateway configuration

    NASA Astrophysics Data System (ADS)

    Palcu, D. V.; Golovina, L. A.; Vernyhorova, Y. V.; Popov, S. V.; Krijgsman, W.

    2017-11-01

    Marine gateways prove to be important factors for changes in the ecology and biochemistry of marginal seas. Changes in gateway configuration played a dominant role in the Middle Miocene paleogeographic evolution of the Paratethys Sea that covered Central Eurasia. Here, we focus on the connection between the Central (CP) and Eastern Paratethys (EP) to understand the paleoenvironmental changes caused by the evolution of this marine gateway. We first construct an integrated magneto-biostratigraphic framework for the late Langhian-Serravallian (Chokrakian-Karaganian-Konkian-Volhynian) sedimentary record of the eastern domain, which allows a correlation to the well-dated successions west of the gateway. The magneto-biostratigraphic results from the Zelensky-Panagia section on the Black Sea coast of Russia show that the Chokrakian/Karaganian boundary has an age of 13.8 Ma, the Karaganian/Konkian boundary is dated at 13.4 Ma, and the Konkian/Volhynian boundary at 12.65 Ma. We identify three major phases on gateway functioning that are reflected in specific environmental changes. During the Karaganian, the EP turned into a lake-sea that supplied a unidirectional flow of low-salinity waters to the west, where the CP sea experienced its Badenian Salinity Crisis. This configuration is remarkably similar to the Mediterranean during its Messinian Salinity Crisis. The second phase is marked by a marine transgression from the west, reinstalling open-marine conditions in the CP and causing marine incursions in the EP during the Konkian. The Volhynian is characterized by a new gateway configuration that allows exchange between CP and EP, creating unified conditions all over the Paratethys. We hypothesize that a density driven pumping mechanism is triggered by the increase in connectivity at the Konkian/Volhynian boundary, which simultaneously caused major paleoenvironmental changes at both sides of the gateway and led to the Badenian-Sarmatian extinction event in the CP.

  20. Note: Methodology for the analysis of Bluetooth gateways in an implemented scatternet.

    PubMed

    Etxaniz, J; Monje, P M; Aranguren, G

    2014-03-01

    This Note introduces a novel methodology to analyze the time performance of Bluetooth gateways in multi-hop networks, known as scatternets. The methodology is focused on distinguishing between the processing time and the time that each communication between nodes takes along an implemented scatternet. This technique is not only valid for Bluetooth networks but also for other wireless networks that offer access to their middleware in order to include beacons in the operation of the nodes. We show in this Note the results of the tests carried out on a Bluetooth scatternet in order to highlight the reliability and effectiveness of the methodology. The results also validate this technique showing convergence in the results when subtracting the time for the beacons from the delay measurements.

  1. Science and Exploration Deep Space Gateway Workshop

    NASA Technical Reports Server (NTRS)

    Spann, James F.

    2017-01-01

    We propose a workshop whose outcome is a publically disseminated product that articulates SMD investigations and HEOMD Life Science research, including international collaborations, that are made possible by the new opportunities in space that result from the Deep Space Gateway.

  2. Autonomous Science Operations Technologies for Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Barnes, P. K.; Haddock, A. T.; Cruzen, C. A.

    2018-02-01

    Autonomous Science Operations Technologies for Deep Space Gateway (DSG) is an overview of how the DSG would benefit from autonomous systems utilizing proven technologies performing telemetry monitoring and science operations.

  3. Advanced distributed simulation technology: Digital Voice Gateway Reference Guide

    NASA Astrophysics Data System (ADS)

    Vanhook, Dan; Stadler, Ed

    1994-01-01

    The Digital Voice Gateway (referred to as the 'DVG' in this document) transmits and receives four full duplex encoded speech channels over the Ethernet. The information in this document applies only to DVG's running firmware of the version listed on the title page. This document, previously named Digital Voice Gateway Reference Guide, BBN Systems and Technologies Corporation, Cambridge, MA 02138, was revised for revision 2.00. This new revision changes the network protocol used by the DVG, to comply with the SINCGARS radio simulation (For SIMNET 6.6.1). Because of the extensive changes to revision 2.00 a separate document was created rather than supplying change pages.

  4. Global Market Access in the Internet Era: South Africa's Wood Furniture Industry.

    ERIC Educational Resources Information Center

    Moodley, Sagren

    2002-01-01

    Explores the link between Internet connectivity and access to global markets, and uses the South African wood furniture producers as they are integrated into global value chains and exposed to the demands of more sophisticated markets. Articulates policy recommendations to promote greater diffusion of e-commerce technologies in the wood furniture…

  5. Access NASA Satellite Global Precipitation Data Visualization on YouTube

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Su, J.; Acker, J. G.; Huffman, G. J.; Vollmer, B.; Wei, J.; Meyer, D. J.

    2017-12-01

    Since the satellite era began, NASA has collected a large volume of Earth science observations for research and applications around the world. Satellite data at 12 NASA data centers can also be used for STEM activities such as disaster events, climate change, etc. However, accessing satellite data can be a daunting task for non-professional users such as teachers and students because of unfamiliarity of terminology, disciplines, data formats, data structures, computing resources, processing software, programing languages, etc. Over the years, many efforts have been developed to improve satellite data access, but barriers still exist for non-professionals. In this presentation, we will present our latest activity that uses the popular online video sharing web site, YouTube, to access visualization of global precipitation datasets at the NASA Goddard Earth Sciences (GES) Data and Information Services Center (DISC). With YouTube, users can access and visualize a large volume of satellite data without necessity to learn new software or download data. The dataset in this activity is the 3-hourly TRMM (Tropical Rainfall Measuring Mission) Multi-satellite Precipitation Analysis (TMPA). The video consists of over 50,000 data files collected since 1998 onwards, covering a zone between 50°N-S. The YouTube video will last 36 minutes for the entire dataset record (over 19 years). Since the time stamp is on each frame of the video, users can begin at any time by dragging the time progress bar. This precipitation animation will allow viewing precipitation events and processes (e.g., hurricanes, fronts, atmospheric rivers, etc.) on a global scale. The next plan is to develop a similar animation for the GPM (Global Precipitation Measurement) Integrated Multi-satellitE Retrievals for GPM (IMERG). The IMERG provides precipitation on a near-global (60°N-S) coverage at half-hourly time interval, showing more details on precipitation processes and development, compared to the 3

  6. Dust Measurements Onboard the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Horanyi, M.; Kempf, S.; Malaspina, D.; Poppe, A.; Srama, R.; Sternovsky, Z.; Szalay, J.

    2018-02-01

    A dust instrument onboard the Deep Space Gateway will revolutionize our understanding of the dust environment at 1 AU, help our understanding of the evolution of the solar system, and improve dust hazard models for the safety of crewed and robotic missions.

  7. Direct SSH Gateway Access to Peregrine | High Performance Computing |

    Science.gov Websites

    can access peregrine-ssh.nrel.gov, you must have: An active NREL HPC user account (see User Accounts ) An OTP Token (see One Time Password Tokens) Logging into peregrine-ssh.nrel.gov With your HPC account

  8. An Integrated Science Glovebox for the Gateway Habitat

    NASA Astrophysics Data System (ADS)

    Calaway, M. J.; Evans, C. A.; Garrison, D. H.; Bell, M. S.

    2018-02-01

    A Deep Space Gateway astromaterials glovebox facility would enable science to return to Earth collected astromaterials from the Moon and ultimately Mars. Next generation habitats will benefit from on-board glovebox capability.

  9. Transferable Output ASCII Data (TOAD) gateway: Version 1.0 user's guide

    NASA Technical Reports Server (NTRS)

    Bingel, Bradford D.

    1991-01-01

    The Transferable Output ASCII Data (TOAD) Gateway, release 1.0 is described. This is a software tool for converting tabular data from one format into another via the TOAD format. This initial release of the Gateway allows free data interchange among the following file formats: TOAD; Standard Interface File (SIF); Program to Optimize Simulated Trajectories (POST) input; Comma Separated Value (TSV); and a general free-form file format. As required, additional formats can be accommodated quickly and easily.

  10. Earth science big data at users' fingertips: the EarthServer Science Gateway Mobile

    NASA Astrophysics Data System (ADS)

    Barbera, Roberto; Bruno, Riccardo; Calanducci, Antonio; Fargetta, Marco; Pappalardo, Marco; Rundo, Francesco

    2014-05-01

    The EarthServer project (www.earthserver.eu), funded by the European Commission under its Seventh Framework Program, aims at establishing open access and ad-hoc analytics on extreme-size Earth Science data, based on and extending leading-edge Array Database technology. The core idea is to use database query languages as client/server interface to achieve barrier-free "mix & match" access to multi-source, any-size, multi-dimensional space-time data -- in short: "Big Earth Data Analytics" - based on the open standards of the Open Geospatial Consortium Web Coverage Processing Service (OGC WCPS) and the W3C XQuery. EarthServer combines both, thereby achieving a tight data/metadata integration. Further, the rasdaman Array Database System (www.rasdaman.com) is extended with further space-time coverage data types. On server side, highly effective optimizations - such as parallel and distributed query processing - ensure scalability to Exabyte volumes. In this contribution we will report on the EarthServer Science Gateway Mobile, an app for both iOS and Android-based devices that allows users to seamlessly access some of the EarthServer applications using SAML-based federated authentication and fine-grained authorisation mechanisms.

  11. Traffic management mechanism for intranets with available-bit-rate access to the Internet

    NASA Astrophysics Data System (ADS)

    Hassan, Mahbub; Sirisena, Harsha R.; Atiquzzaman, Mohammed

    1997-10-01

    The design of a traffic management mechanism for intranets connected to the Internet via an available bit rate access- link is presented. Selection of control parameters for this mechanism for optimum performance is shown through analysis. An estimate for packet loss probability at the access- gateway is derived for random fluctuation of available bit rate of the access-link. Some implementation strategies of this mechanism in the standard intranet protocol stack are also suggested.

  12. Changing global essential medicines norms to improve access to AIDS treatment: lessons from Brazil.

    PubMed

    Nunn, A; Fonseca, E Da; Gruskin, S

    2009-01-01

    Brazil's large-scale, successful HIV/AIDS treatment programme is considered by many to be a model for other developing countries aiming to improve access to AIDS treatment. Far less is known about Brazil's important role in changing global norms related to international pharmaceutical policy, particularly international human rights, health and trade policies governing access to essential medicines. Prompted by Brazil's interest in preserving its national AIDS treatment policies during World Trade Organisation trade disputes with the USA, these efforts to change global essential medicines norms have had important implications for other countries, particularly those scaling up AIDS treatment. This paper analyses Brazil's contributions to global essential medicines policy and explains the relevance of Brazil's contributions to global health policy today.

  13. Changing global essential medicines norms to improve access to AIDS treatment: Lessons from Brazil

    PubMed Central

    Nunn, A.; Fonseca, E. Da; Gruskin, S.

    2009-01-01

    Brazil's large-scale, successful HIV/AIDS treatment programme is considered by many to be a model for other developing countries aiming to improve access to AIDS treatment. Far less is known about Brazil's important role in changing global norms related to international pharmaceutical policy, particularly international human rights, health and trade policies governing access to essential medicines. Prompted by Brazil's interest in preserving its national AIDS treatment policies during World Trade Organisation trade disputes with the USA, these efforts to change global essential medicines norms have had important implications for other countries, particularly those scaling up AIDS treatment. This paper analyses Brazil's contributions to global essential medicines policy and explains the relevance of Brazil's contributions to global health policy today. PMID:19333805

  14. Evaluation of R1-6 gateway treatment alternatives for pedestrian crossings : final report.

    DOT National Transportation Integrated Search

    2016-02-01

    A series of studies evaluated the Gateway configuration of R1-6 in-street signs. A Gateway configuration consists of an R1-6 sign on the centerline, an R1-6 signs on both edges of the roadway, and R1-6 signs on the lane lines if it is a multilane roa...

  15. 76 FR 48834 - Michigan Consolidated Gas Company and Dawn Gateway Pipeline, LLC; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-09

    ...'s Belle River-St. Clair Pipeline into the new 21-mile long Dawn Gateway Pipeline system, which... & Optimization, DTE Pipeline/Dawn Gateway LLC, One Energy Plaza, Detroit, MI 48226, phone (313) 235-6531 or e...

  16. Global Access Programs: A Collaborative Approach for Effective Implementation and Management.

    PubMed

    Ainge, Debra; Aitken, Suzanne; Corbett, Mark; De-Keyzer, David

    Global access programs (GAPs) provide access to medicinal products for patients with serious medical conditions and no commercially available treatment options. Providing early access to medicines can be challenging for a pharmaceutical company. The demand for a GAP often occurs at a time when other activities are the prime focus, such as delivery of pivotal clinical trials or gaining of marketing authorization. Furthermore, the skills, experience, and infrastructure necessary to implement and manage a successful GAP vary significantly from those required for regular clinical trial execution, and the regulatory environment presents its own challenges, with regulations often poorly defined and with considerable inter-country variation. This article considers the triggers for early access requests and examines the need for companies to develop a global strategy for GAPs in order to respond appropriately to requests for early access. It also provides a comprehensive overview of the processes for GAP set-up, implementation, management, and closure, along with the considerations affecting the type and scope of GAP, such as demand, regulatory feasibility, license status of the product, drug pricing structure, company strategy, costs, and product supply. Also discussed is the need for appropriate personnel to implement and manage the GAP, and when to consider collaboration with an external GAP provider. In summary, GAPs require careful and efficient planning and management, from set-up to closure. Well-run GAPs provide an ethical and regulatory-compliant pathway for access of new treatments to patients with serious conditions and an unmet medical need.

  17. Global pharmaceutical development and access: critical issues of ethics and equity.

    PubMed

    Lage, Agustín

    2011-07-01

    The article presents global data on access to pharmaceuticals and discusses underlying barriers. Two are highly visible: pricing policies and intellectual property rights; two are less recognized: the regulatory environment and scientific and technological capacities. Two ongoing transitions influence and even distort the problem of universal access to medications: the epidemiologic transition to an increasing burden of chronic non-communicable diseases; and the growing role of biotechnology products (especially immunobiologicals) in the pharmacopeia. Examples from Cuba and Brazil are used to explore what can and should be done to address commercial, regulatory, and technological aspects of assuring universal access to medications.

  18. RESTful M2M gateway for remote wireless monitoring for district central heating networks.

    PubMed

    Cheng, Bo; Wei, Zesan

    2014-11-27

    In recent years, the increased interest in energy conservation and environmental protection, combined with the development of modern communication and computer technology, has resulted in the replacement of distributed heating by central heating in urban areas. This paper proposes a Representational State Transfer (REST) Machine-to-Machine (M2M) gateway for wireless remote monitoring for a district central heating network. In particular, we focus on the resource-oriented RESTful M2M gateway architecture, and present an uniform devices abstraction approach based on Open Service Gateway Initiative (OSGi) technology, and implement the resource mapping mechanism between resource address mapping mechanism between RESTful resources and the physical sensor devices, and present the buffer queue combined with polling method to implement the data scheduling and Quality of Service (QoS) guarantee, and also give the RESTful M2M gateway open service Application Programming Interface (API) set. The performance has been measured and analyzed. Finally, the conclusions and future work are presented.

  19. RESTful M2M Gateway for Remote Wireless Monitoring for District Central Heating Networks

    PubMed Central

    Cheng, Bo; Wei, Zesan

    2014-01-01

    In recent years, the increased interest in energy conservation and environmental protection, combined with the development of modern communication and computer technology, has resulted in the replacement of distributed heating by central heating in urban areas. This paper proposes a Representational State Transfer (REST) Machine-to-Machine (M2M) gateway for wireless remote monitoring for a district central heating network. In particular, we focus on the resource-oriented RESTful M2M gateway architecture, and present an uniform devices abstraction approach based on Open Service Gateway Initiative (OSGi) technology, and implement the resource mapping mechanism between resource address mapping mechanism between RESTful resources and the physical sensor devices, and present the buffer queue combined with polling method to implement the data scheduling and Quality of Service (QoS) guarantee, and also give the RESTful M2M gateway open service Application Programming Interface (API) set. The performance has been measured and analyzed. Finally, the conclusions and future work are presented. PMID:25436650

  20. Analytic Patch Configuration (APC) gateway version 1.0 user's guide

    NASA Technical Reports Server (NTRS)

    Bingel, Bradford D.

    1990-01-01

    The Analytic Patch Configuration (APC) is an interactive software tool which translates aircraft configuration geometry files from one format into another. This initial release of the APC Gateway accommodates six formats: the four accepted APC formats (89f, 89fd, 89u, and 89ud), the PATRAN 2.x phase 1 neutral file format, and the Integrated Aerodynamic Analysis System (IAAS) General Geometry (GG) format. Written in ANSI FORTRAN 77 and completely self-contained, the APC Gateway is very portable and was already installed on CDC/NOS, VAX/VMS, SUN, SGI/IRIS, CONVEX, and GRAY hosts.

  1. The Cybermobile: A Gateway for Public Access to Network-Based Information.

    ERIC Educational Resources Information Center

    Drumm, John E.; Groom, Frank M.

    1997-01-01

    Though the bookmobile has fallen on hard times, the cybermobile, a technology platform combining personal computing, CD-ROMs, fiber network, and wireless access to the Internet, may be the next step in mobile library services. Discusses standard vehicle, computer hardware, software, wireless access, and alliances with users, vendors, and community…

  2. An Analysis of Gateway Technical College Instructors' Opinions on Secondary and Postsecondary Program Alignment

    ERIC Educational Resources Information Center

    Albrecht, Bryan D.

    2011-01-01

    The purpose of this study was to determine what opinions Gateway Technical College instructors had toward secondary and postsecondary program alignment. Student transition is critical to supporting the mission and vision of Gateway Technical College. The impetus for this study was twofold. First, the quality improvement process established at…

  3. Access NASA Satellite Global Precipitation Data Visualization on YouTube

    NASA Technical Reports Server (NTRS)

    Liu, Z.; Su, J.; Acker, J.; Huffman, G.; Vollmer, B.; Wei, J.; Meyer, D.

    2017-01-01

    Since the satellite era began, NASA has collected a large volume of Earth science observations for research and applications around the world. The collected and archived satellite data at 12 NASA data centers can also be used for STEM education and activities such as disaster events, climate change, etc. However, accessing satellite data can be a daunting task for non-professional users such as teachers and students because of unfamiliarity of terminology, disciplines, data formats, data structures, computing resources, processing software, programming languages, etc. Over the years, many efforts including tools, training classes, and tutorials have been developed to improve satellite data access for users, but barriers still exist for non-professionals. In this presentation, we will present our latest activity that uses a very popular online video sharing Web site, YouTube (https://www.youtube.com/), for accessing visualizations of our global precipitation datasets at the NASA Goddard Earth Sciences (GES) Data and Information Services Center (DISC). With YouTube, users can access and visualize a large volume of satellite data without the necessity to learn new software or download data. The dataset in this activity is a one-month animation for the GPM (Global Precipitation Measurement) Integrated Multi-satellite Retrievals for GPM (IMERG). IMERG provides precipitation on a near-global (60 deg. N-S) coverage at half-hourly time interval, providing more details on precipitation processes and development compared to the 3-hourly TRMM (Tropical Rainfall Measuring Mission) Multisatellite Precipitation Analysis (TMPA, 3B42) product. When the retro-processing of IMERG during the TRMM era is finished in 2018, the entire video will contain more than 330,000 files and will last 3.6 hours. Future plans include development of flyover videos for orbital data for an entire satellite mission or project. All videos, including the one-month animation, will be uploaded and

  4. Excluding the poor from accessing biomedical literature: a rights violation that impedes global health.

    PubMed

    Yamey, Gavin

    2008-01-01

    Most biomedical journals charge readers a hefty access toll to read the full text version of a published research article. These tolls bring enormous profits to the traditional corporate publishing industry, but they make it impossible for most people worldwide--particularly in low and middle income countries--to access the biomedical literature. Traditional publishers also insist on owning the copyright on these articles, making it illegal for readers to freely distribute and photocopy papers, translate them, or create derivative educational works. This article argues that excluding the poor from accessing and freely using the biomedical research literature is harming global public health. Health care workers, for example, are prevented from accessing the information they need to practice effective medicine, while policymakers are prevented from accessing the essential knowledge they require to build better health care systems. The author proposes that the biomedical literature should be considered a global public good, basing his arguments upon longstanding and recent international declarations that enshrine access to scientific and medical knowledge as a human right. He presents an emerging alternative publishing model, called open access, and argues that this model is a more socially responsive and equitable approach to knowledge dissemination.

  5. Gateway: An earth orbiting transportation node

    NASA Technical Reports Server (NTRS)

    1988-01-01

    University of Texas Mission Design (UTMD) has outlined the components that a space based transportation facility must include in order to support the first decade of Lunar base buildup. After studying anticipated traffic flow to and from the hub, and taking into account crew manhour considerations, propellant storage, orbital transfer vehicle maintenance requirements, and orbital mechanics, UTMD arrived at a design for the facility. The amount of activity directly related to supporting Lunar base traffic is too high to allow the transportation hub to be part of the NASA Space Station. Instead, a separate structure should be constructed and dedicated to handling all transportation-related duties. UTMD found that the structure (named Gateway) would need a permanent crew of four to perform maintenance tasks on the orbital transfer and orbital maneuvering vehicles and to transfer payload from launch vehicles to the orbital transfer vehicles. In addition, quarters for 4 more persons should be allocated for temporary accommodation of Lunar base crew passing through Gateway. UTMD was careful to recommend an expendable structure that can adapt to meet the growing needs of the American space program.

  6. Van Allen Probes Science Gateway and Space Weather Data Processing

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Weiss, M.; Fox, N. J.; Mauk, B.; Potter, M.; Kessel, R.

    2014-12-01

    The Van Allen Probes Science Gateway acts as a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the VAP Space Weather data to users. Over the past year, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes summary and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including simple time series, data plotted as a function of orbital location, and time versus L-Shell. We discuss the new Van Allen Probes Science Gateway and the Space Weather Data Pipeline.

  7. Multi-Modal Traveler Information System - Gateway Design Options

    DOT National Transportation Integrated Search

    1997-05-19

    The purpose of this working paper is to provide insight into the options that are available from which to design the Gateway Traveler Information System (TIS). This working paper will discuss each option in a general manner without becoming overly te...

  8. GATEWAY Report Brief: OLED Lighting in the Offices of Aurora Lighting Design, Inc.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    Summary of a GATEWAY report evaluation at the offices of Aurora Lighting Design, Inc., in Grayslake, IL, where the GATEWAY program conducted its first investigation involving OLED lighting. The project experienced several challenges, but also highlighted a number of promising attributes – which indicate that with continued improvements in efficacy, longevity, size, and flexibility, OLEDs could provide a new tool for creative and effective lighting.

  9. Balancing Open Access with Academic Standards: Implications for Community College Faculty

    ERIC Educational Resources Information Center

    Gabbard, Anita; Mupinga, Davison M.

    2013-01-01

    Community colleges act as the gateway for students to higher education. Many of these colleges realize this mission through open-door policies where students lacking in basic reading, writing, and mathematics skills can enroll. But, this open-access policy often creates challenges when meeting academic standards. Based on data collected from…

  10. "Gateway" Districts Struggle to Serve Immigrant Parents

    ERIC Educational Resources Information Center

    Maxwell, Lesli A.

    2012-01-01

    As thousands of communities--especially in the South--became booming gateways for immigrant families during the 1990s and the early years of the new century, public schools struggled with the unfamiliar task of serving the large numbers of English-learners arriving in their classrooms. Instructional programs were built from scratch. Districts had…

  11. 77 FR 46435 - Notice To All Interested Parties of the Termination of the Receivership of 10146, Gateway Bank of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... Receivership of 10146, Gateway Bank of St. Louis, St. Louis, MO Notice is hereby given that the Federal Deposit Insurance Corporation (``FDIC'') as Receiver for Gateway Bank of St. Louis, (``the Receiver'') intends to terminate its receivership for said institution. The FDIC was appointed receiver of Gateway Bank of St...

  12. Volcano Modelling and Simulation gateway (VMSg): A new web-based framework for collaborative research in physical modelling and simulation of volcanic phenomena

    NASA Astrophysics Data System (ADS)

    Esposti Ongaro, T.; Barsotti, S.; de'Michieli Vitturi, M.; Favalli, M.; Longo, A.; Nannipieri, L.; Neri, A.; Papale, P.; Saccorotti, G.

    2009-12-01

    Physical and numerical modelling is becoming of increasing importance in volcanology and volcanic hazard assessment. However, new interdisciplinary problems arise when dealing with complex mathematical formulations, numerical algorithms and their implementations on modern computer architectures. Therefore new frameworks are needed for sharing knowledge, software codes, and datasets among scientists. Here we present the Volcano Modelling and Simulation gateway (VMSg, accessible at http://vmsg.pi.ingv.it), a new electronic infrastructure for promoting knowledge growth and transfer in the field of volcanological modelling and numerical simulation. The new web portal, developed in the framework of former and ongoing national and European projects, is based on a dynamic Content Manager System (CMS) and was developed to host and present numerical models of the main volcanic processes and relationships including magma properties, magma chamber dynamics, conduit flow, plume dynamics, pyroclastic flows, lava flows, etc. Model applications, numerical code documentation, simulation datasets as well as model validation and calibration test-cases are also part of the gateway material.

  13. The Deep Space Gateway Lightning Mapper (DLM) — Monitoring Global Change and Thunderstorm Processes through Observations of Earth's High-Latitude Lightning from Cis-Lunar Orbit

    NASA Astrophysics Data System (ADS)

    Lang, T. J.; Blakeslee, R. J.; Cecil, D. J.; Christian, H. J.; Gatlin, P. N.; Goodman, S. J.; Koshak, W. J.; Petersen, W. A.; Quick, M.; Schultz, C. J.; Tatum, P. F.

    2018-02-01

    We propose the Deep Space Gateway Lightning Mapper (DLM) instrument. The primary goal of the DLM is to optically monitor Earth's high-latitude (50° and poleward) total lightning not observed by current and planned spaceborne lightning mappers.

  14. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM... that each Participating Commercial Mobile Service provider is required to support and perform at its...

  15. Improving Global Precipitation Product Access at the GES DISC

    NASA Technical Reports Server (NTRS)

    Liu, Z.; Vollmer, B.; Savtchenko, A.; Ostrenga, D.; DeShong, B.; Fang, F.; Albayrak, R,; Sherman, E.; Greene, M.; Li, A.; hide

    2018-01-01

    The NASA Goddard Earth Sciences Data and Information Services Center (GES DISC) has been actively and continually engaged in improving the access to and use of Global Precipitation Measurement (GPM), Tropical Precipitation Measuring Mission (TRMM), and other precipitation data, including the following new services and Ongoing development activities: Updates on GPM products and data services, New features in Giovanni, Ongoing development activities; and Precipitation product and service outreach activities.

  16. Raising Virtual Laboratories in Australia onto global platforms

    NASA Astrophysics Data System (ADS)

    Wyborn, L. A.; Barker, M.; Fraser, R.; Evans, B. J. K.; Moloney, G.; Proctor, R.; Moise, A. F.; Hamish, H.

    2016-12-01

    Across the globe, Virtual Laboratories (VLs), Science Gateways (SGs), and Virtual Research Environments (VREs) are being developed that enable users who are not co-located to actively work together at various scales to share data, models, tools, software, workflows, best practices, etc. Outcomes range from enabling `long tail' researchers to more easily access specific data collections, to facilitating complex workflows on powerful supercomputers. In Australia, government funding has facilitated the development of a range of VLs through the National eResearch Collaborative Tools and Resources (NeCTAR) program. The VLs provide highly collaborative, research-domain oriented, integrated software infrastructures that meet user community needs. Twelve VLs have been funded since 2012, including the Virtual Geophysics Laboratory (VGL); Virtual Hazards, Impact and Risk Laboratory (VHIRL); Climate and Weather Science Laboratory (CWSLab); Marine Virtual Laboratory (MarVL); and Biodiversity and Climate Change Virtual Laboratory (BCCVL). These VLs share similar technical challenges, with common issues emerging on integration of tools, applications and access data collections via both cloud-based environments and other distributed resources. While each VL began with a focus on a specific research domain, communities of practice have now formed across the VLs around common issues, and facilitate identification of best practice case studies, and new standards. As a result, tools are now being shared where the VLs access data via data services using international standards such as ISO, OGC, W3C. The sharing of these approaches is starting to facilitate re-usability of infrastructure and is a step towards supporting interdisciplinary research. Whilst the focus of the VLs are Australia-centric, by using standards, these environments are able to be extended to analysis on other international datasets. Many VL datasets are subsets of global datasets and so extension to global is a

  17. Calculus ABCs: A Gateway for Freshman Calculus

    ERIC Educational Resources Information Center

    Fulton, Scott R.

    2003-01-01

    This paper describes a gateway testing program designed to ensure that students acquire basic skills in freshman calculus. Students must demonstrate they have mastered standards for "Absolutely Basic Competency"--the Calculus ABCs--in order to pass the course with a grade of C or better. We describe the background, standards, and testing program.…

  18. Redefining nondiscriminatory access to remote sensing imagery and its impact on global transparency

    NASA Astrophysics Data System (ADS)

    Aten, Michelle L.

    2003-04-01

    Global transparency is founded on the Open Skies philosophy and its precept of non-discriminatory access. Global transparency implies that anyone can have anytime, anyplace access to a wide-array of remotely sensed imagery. The custom of non-discriminatory access requires that datasets of interest must be affordable, usable, and obtainable in a timely fashion devoid of political, economic or technical obstacles. Thus, an assessment of the correlation between the availability of satellite imagery and changes in governmental policies, pricing fluctuations of data, and advances in technology is critical to assessing the viability of global transparency. The Open Skies philosophy was originally proposed at the 1955 Geneva Summit to advocate mutually beneficial aerial reconnaissance missions over the USSR and the US as a verification tool for arms control and non-proliferation agreements. However, due to Cold War tensions, this philosophy and the custom of non-discriminatory were not widely adopted in the civilian remote sensing community until the commissioning of the Landsat Program in 1972. Since this time, commercial high-resolution satellites have drastically changed the circumstances on which the fundamental tenets of this philosophy are based. Since the successful launch of the first of this satellite class, the IKONOS satellite, high-resolution imagery is now available to non-US governments and an unlimited set of non-state actors. As more advanced capabilities are added to the growing assortment of remote sensing satellites, the reality of global transparency will rapidly evolve. This assessment includes an overview of historical precedents and a brief explanation of relevant US policy decisions that define non-discriminatory access with respect to US government and US based corporate assets. It also presents the dynamics of the political, economic, and technical barriers that may dictate or influence the remote sensing community's access to satellite data. In

  19. An Intelligent Cloud Storage Gateway for Medical Imaging.

    PubMed

    Viana-Ferreira, Carlos; Guerra, António; Silva, João F; Matos, Sérgio; Costa, Carlos

    2017-09-01

    Historically, medical imaging repositories have been supported by indoor infrastructures. However, the amount of diagnostic imaging procedures has continuously increased over the last decades, imposing several challenges associated with the storage volume, data redundancy and availability. Cloud platforms are focused on delivering hardware and software services over the Internet, becoming an appealing solution for repository outsourcing. Although this option may bring financial and technological benefits, it also presents new challenges. In medical imaging scenarios, communication latency is a critical issue that still hinders the adoption of this paradigm. This paper proposes an intelligent Cloud storage gateway that optimizes data access times. This is achieved through a new cache architecture that combines static rules and pattern recognition for eviction and prefetching. The evaluation results, obtained from experiments over a real-world dataset, show that cache hit ratios can reach around 80%, leading to reductions of image retrieval times by over 60%. The combined use of eviction and prefetching policies proposed can significantly reduce communication latency, even when using a small cache in comparison to the total size of the repository. Apart from the performance gains, the proposed system is capable of adjusting to specific workflows of different institutions.

  20. Improving global access to new vaccines: intellectual property, technology transfer, and regulatory pathways.

    PubMed

    Crager, Sara Eve

    2014-11-01

    The 2012 World Health Assembly Global Vaccine Action Plan called for global access to new vaccines within 5 years of licensure. Current approaches have proven insufficient to achieve sustainable vaccine pricing within such a timeline. Paralleling the successful strategy of generic competition to bring down drug prices, a clear consensus is emerging that market entry of multiple suppliers is a critical factor in expeditiously bringing down prices of new vaccines. In this context, key target objectives for improving access to new vaccines include overcoming intellectual property obstacles, streamlining regulatory pathways for biosimilar vaccines, and reducing market entry timelines for developing-country vaccine manufacturers by transfer of technology and know-how. I propose an intellectual property, technology, and know-how bank as a new approach to facilitate widespread access to new vaccines in low- and middle-income countries by efficient transfer of patented vaccine technologies to multiple developing-country vaccine manufacturers.

  1. [Improving global access to new vaccines: intellectual property, technology transfer, and regulatory pathways].

    PubMed

    Crager, Sara Eve

    2015-01-01

    The 2012 World Health Assembly Global Vaccine Action Plan called for global access to new vaccines within 5 years of licensure. Current approaches have proven insufficient to achieve sustainable vaccine pricing within such a timeline. Paralleling the successful strategy of generic competition to bring down drug prices, a clear consensus is emerging that market entry of multiple suppliers is a critical factor in expeditiously bringing down prices of new vaccines. In this context, key target objectives for improving access to new vaccines include overcoming intellectual property obstacles, streamlining regulatory pathways for biosimilar vaccines, and reducing market entry timelines for developing-country vaccine manufacturers by transfer of technology and know-how. I propose an intellectual property, technology, and know-how bank as a new approach to facilitate widespread access to new vaccines in low- and middle-income countries by efficient transfer of patented vaccine technologies to multiple developing-country vaccine manufacturers.

  2. Late Cretaceous climate simulations with different CO2 levels and subarctic gateway configurations: A model-data comparison

    NASA Astrophysics Data System (ADS)

    Niezgodzki, Igor; Knorr, Gregor; Lohmann, Gerrit; Tyszka, Jarosław; Markwick, Paul J.

    2017-09-01

    We investigate the impact of different CO2 levels and different subarctic gateway configurations on the surface temperatures during the latest Cretaceous using the Earth System Model COSMOS. The simulated temperatures are compared with the surface temperature reconstructions based on a recent compilation of the latest Cretaceous proxies. In our numerical experiments, the CO2 level ranges from 1 to 6 times the preindustrial (PI) CO2 level of 280 ppm. On a global scale, the most reasonable match between modeling and proxy data is obtained for the experiments with 3 to 5 × PI CO2 concentrations. However, the simulated low- (high-) latitude temperatures are too high (low) as compared to the proxy data. The moderate CO2 levels scenarios might be more realistic, if we take into account proxy data and the dead zone effect criterion. Furthermore, we test if the model-data discrepancies can be caused by too simplistic proxy-data interpretations. This is distinctly seen at high latitudes, where most proxies are biased toward summer temperatures. Additional sensitivity experiments with different ocean gateway configurations and constant CO2 level indicate only minor surface temperatures changes (< 1°C) on a global scale, with higher values (up to 8°C) on a regional scale. These findings imply that modeled and reconstructed temperature gradients are to a large degree only qualitatively comparable, providing challenges for the interpretation of proxy data and/or model sensitivity. With respect to the latter, our results suggest that an assessment of greenhouse worlds is best constrained by temperatures in the midlatitudes.

  3. Gateway to Careers. Postsecondary VSO Hones Workplace Skills.

    ERIC Educational Resources Information Center

    Vernezze, Michael; Henkel, Marjorie

    1993-01-01

    The Gateway Marketing and Management Association is a local chapter of Delta Epsilon Chi, the postsecondary affiliate of Distributive Education Clubs of America. This vocational student organization provides leadership training and marketing skill development to prepare students for competition at state and national levels. (JOW)

  4. Does global progress on sanitation really lag behind water? An analysis of global progress on community- and household-level access to safe water and sanitation.

    PubMed

    Cumming, Oliver; Elliott, Mark; Overbo, Alycia; Bartram, Jamie

    2014-01-01

    Safe drinking water and sanitation are important determinants of human health and wellbeing and have recently been declared human rights by the international community. Increased access to both were included in the Millennium Development Goals under a single dedicated target for 2015. This target was reached in 2010 for water but sanitation will fall short; however, there is an important difference in the benchmarks used for assessing global access. For drinking water the benchmark is community-level access whilst for sanitation it is household-level access, so a pit latrine shared between households does not count toward the Millennium Development Goal (MDG) target. We estimated global progress for water and sanitation under two scenarios: with equivalent household- and community-level benchmarks. Our results demonstrate that the "sanitation deficit" is apparent only when household-level sanitation access is contrasted with community-level water access. When equivalent benchmarks are used for water and sanitation, the global deficit is as great for water as it is for sanitation, and sanitation progress in the MDG-period (1990-2015) outstrips that in water. As both drinking water and sanitation access yield greater benefits at the household-level than at the community-level, we conclude that any post-2015 goals should consider a household-level benchmark for both.

  5. Enabling Research without Geographical Boundaries via Collaborative Research Infrastructures

    NASA Astrophysics Data System (ADS)

    Gesing, S.

    2016-12-01

    Collaborative research infrastructures on global scale for earth and space sciences face a plethora of challenges from technical implementations to organizational aspects. Science gateways - also known as virtual research environments (VREs) or virtual laboratories - address part of such challenges by providing end-to-end solutions to aid researchers to focus on their specific research questions without the need to become acquainted with the technical details of the complex underlying infrastructures. In general, they provide a single point of entry to tools and data irrespective of organizational boundaries and thus make scientific discoveries easier and faster. The importance of science gateways has been recognized on national as well as on international level by funding bodies and by organizations. For example, the US NSF has just funded a Science Gateways Community Institute, which offers support, consultancy and open accessible software repositories for users and developers; Horizon 2020 provides funding for virtual research environments in Europe, which has led to projects such as VRE4EIC (A Europe-wide Interoperable Virtual Research Environment to Empower Multidisciplinary Research Communities and Accelerate Innovation and Collaboration); national or continental research infrastructures such as XSEDE in the USA, Nectar in Australia or EGI in Europe support the development and uptake of science gateways; the global initiatives International Coalition on Science Gateways, the RDA Virtual Research Environment Interest Group as well as the IEEE Technical Area on Science Gateways have been founded to provide global leadership on future directions for science gateways in general and facilitate awareness for science gateways. This presentation will give an overview on these projects and initiatives aiming at supporting domain researchers and developers with measures for the efficient creation of science gateways, for increasing their usability and sustainability

  6. A Gateway for Phylogenetic Analysis Powered by Grid Computing Featuring GARLI 2.0

    PubMed Central

    Bazinet, Adam L.; Zwickl, Derrick J.; Cummings, Michael P.

    2014-01-01

    We introduce molecularevolution.org, a publicly available gateway for high-throughput, maximum-likelihood phylogenetic analysis powered by grid computing. The gateway features a garli 2.0 web service that enables a user to quickly and easily submit thousands of maximum likelihood tree searches or bootstrap searches that are executed in parallel on distributed computing resources. The garli web service allows one to easily specify partitioned substitution models using a graphical interface, and it performs sophisticated post-processing of phylogenetic results. Although the garli web service has been used by the research community for over three years, here we formally announce the availability of the service, describe its capabilities, highlight new features and recent improvements, and provide details about how the grid system efficiently delivers high-quality phylogenetic results. [garli, gateway, grid computing, maximum likelihood, molecular evolution portal, phylogenetics, web service.] PMID:24789072

  7. Understanding nuclear motions in molecules: Derivation of Eckart frame ro-vibrational Hamiltonian operators via a gateway Hamiltonian operator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Szalay, Viktor, E-mail: szalay.viktor@wigner.mta.hu

    A new ro-vibrational Hamiltonian operator, named gateway Hamiltonian operator, with exact kinetic energy term, T-hat, is presented. It is in the Eckart frame and it is of the same form as Watson’s normal coordinate Hamiltonian. However, the vibrational coordinates employed are not normal coordinates. The new Hamiltonian is shown to provide easy access to Eckart frame ro-vibrational Hamiltonians with exact T-hat given in terms of any desired set of vibrational coordinates. A general expression of the Eckart frame ro-vibrational Hamiltonian operator is given and some of its properties are discussed.

  8. Starshade Assembly Enabled by the Deep Space Gateway Architecture

    NASA Astrophysics Data System (ADS)

    Grunsfeld, J. M.; Siegler, N.; Mukherjee, R.

    2018-02-01

    A starshade is a large external coronagraph which will allow the direct imaging and analysis of planets around nearby stars. We present how the Deep Space Gateway would enable the robotic/astronaut construction of a starshade.

  9. GATEWAY Demonstrations: Exploring SSL Product Performance in the Real World

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Fact sheet that outlines DOE's GATEWAY technology demonstration program, which evaluates high-performance SSL products for general illumination in a variety of real-world exterior and interior applications.

  10. Improving Global Access to New Vaccines: Intellectual Property, Technology Transfer, and Regulatory Pathways

    PubMed Central

    2014-01-01

    The 2012 World Health Assembly Global Vaccine Action Plan called for global access to new vaccines within 5 years of licensure. Current approaches have proven insufficient to achieve sustainable vaccine pricing within such a timeline. Paralleling the successful strategy of generic competition to bring down drug prices, a clear consensus is emerging that market entry of multiple suppliers is a critical factor in expeditiously bringing down prices of new vaccines. In this context, key target objectives for improving access to new vaccines include overcoming intellectual property obstacles, streamlining regulatory pathways for biosimilar vaccines, and reducing market entry timelines for developing-country vaccine manufacturers by transfer of technology and know-how. I propose an intellectual property, technology, and know-how bank as a new approach to facilitate widespread access to new vaccines in low- and middle-income countries by efficient transfer of patented vaccine technologies to multiple developing-country vaccine manufacturers. PMID:25211753

  11. GermOnline 4.0 is a genomics gateway for germline development, meiosis and the mitotic cell cycle.

    PubMed

    Lardenois, Aurélie; Gattiker, Alexandre; Collin, Olivier; Chalmel, Frédéric; Primig, Michael

    2010-01-01

    GermOnline 4.0 is a cross-species database portal focusing on high-throughput expression data relevant for germline development, the meiotic cell cycle and mitosis in healthy versus malignant cells. It is thus a source of information for life scientists as well as clinicians who are interested in gene expression and regulatory networks. The GermOnline gateway provides unlimited access to information produced with high-density oligonucleotide microarrays (3'-UTR GeneChips), genome-wide protein-DNA binding assays and protein-protein interaction studies in the context of Ensembl genome annotation. Samples used to produce high-throughput expression data and to carry out genome-wide in vivo DNA binding assays are annotated via the MIAME-compliant Multiomics Information Management and Annotation System (MIMAS 3.0). Furthermore, the Saccharomyces Genomics Viewer (SGV) was developed and integrated into the gateway. SGV is a visualization tool that outputs genome annotation and DNA-strand specific expression data produced with high-density oligonucleotide tiling microarrays (Sc_tlg GeneChips) which cover the complete budding yeast genome on both DNA strands. It facilitates the interpretation of expression levels and transcript structures determined for various cell types cultured under different growth and differentiation conditions. Database URL: www.germonline.org/

  12. GermOnline 4.0 is a genomics gateway for germline development, meiosis and the mitotic cell cycle

    PubMed Central

    Lardenois, Aurélie; Gattiker, Alexandre; Collin, Olivier; Chalmel, Frédéric; Primig, Michael

    2010-01-01

    GermOnline 4.0 is a cross-species database portal focusing on high-throughput expression data relevant for germline development, the meiotic cell cycle and mitosis in healthy versus malignant cells. It is thus a source of information for life scientists as well as clinicians who are interested in gene expression and regulatory networks. The GermOnline gateway provides unlimited access to information produced with high-density oligonucleotide microarrays (3′-UTR GeneChips), genome-wide protein–DNA binding assays and protein–protein interaction studies in the context of Ensembl genome annotation. Samples used to produce high-throughput expression data and to carry out genome-wide in vivo DNA binding assays are annotated via the MIAME-compliant Multiomics Information Management and Annotation System (MIMAS 3.0). Furthermore, the Saccharomyces Genomics Viewer (SGV) was developed and integrated into the gateway. SGV is a visualization tool that outputs genome annotation and DNA-strand specific expression data produced with high-density oligonucleotide tiling microarrays (Sc_tlg GeneChips) which cover the complete budding yeast genome on both DNA strands. It facilitates the interpretation of expression levels and transcript structures determined for various cell types cultured under different growth and differentiation conditions. Database URL: www.germonline.org/ PMID:21149299

  13. Assessing 15 proposals for promoting innovation and access to medicines globally.

    PubMed

    Hoffman, Steven J; So, Karen

    2014-01-01

    There is widespread recognition that the existing global systems for innovation and access to medicines need reform. Billions of people do not have access to the medicines they need, and market failures prevent new drugs from being developed for diseases that primarily affect the global poor. The World Health Organization's Consultative Expert Working Group on Research and Development: Financing and Coordination (CEWG) analyzed numerous proposals for reform. The aim of this article is to build on these previous inquiries. We conducted a structured analysis that grouped proposals into five broad opportunities for global policy reform to help researchers and decision makers to meaningfully evaluate each proposal in comparison with similar proposals. Proposals were also analyzed along three important dimensions-potential health impact, financial implications, and political feasibility-further facilitating the comparison and application of this information. Upon analysis, no one solution was deemed a panacea, as many (often competing) considerations need to be taken into account. However, some proposals, particularly product development partnership and prizes, appeared more promising and feasible at this time and deserve further attention. More research is needed into the effectiveness of these mechanisms and their transferability across jurisdictions. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  14. Global Access to Library of Congress' Digital Resources: National Digital Library and Internet Resources.

    ERIC Educational Resources Information Center

    Chen, Ching-chih

    1996-01-01

    Summarizes how the Library of Congress' digital library collections can be accessed globally via the Internet and World Wide Web. Outlines the resources found in each of the various access points: gopher, online catalog, library and legislative Web sites, legal and copyright databases, and FTP (file transfer protocol) sites. (LAM)

  15. All gates lead to smoking: the 'gateway theory', e-cigarettes and the remaking of nicotine.

    PubMed

    Bell, Kirsten; Keane, Helen

    2014-10-01

    The idea that drug use in 'softer' forms leads to 'harder' drug use lies at the heart of the gateway theory, one of the most influential models of drug use of the twentieth century. Although hotly contested, the notion of the 'gateway drug' continues to rear its head in discussions of drug use--most recently in the context of electronic cigarettes. Based on a critical reading of a range of texts, including scholarly literature and media reports, we explore the history and gestation of the gateway theory, highlighting the ways in which intersections between academic, media and popular accounts actively produced the concept. Arguing that the theory has been critical in maintaining the distinction between 'soft' and 'hard' drugs, we turn to its distinctive iteration in the context of debates about e-cigarettes. We show that the notion of the 'gateway' has been transformed from a descriptive to a predictive model, one in which nicotine is constituted as simultaneously 'soft' and 'hard'--as both relatively innocuous and incontrovertibly harmful. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Deployed Communications in an Austere Environment: A Delphi Study

    DTIC Science & Technology

    2013-12-01

    gateways to access the Global Information Grid ( GIG ) will escalate dramatically. The ability simply to “deploy” a unit similar to the RF- SATCOM network...experts had divergent views on how deployed communications systems would link back to the GIG . The scenario uses both projected technologies. First...the self-configuring RF-SATCOM network link acts as a gateway to the GIG , providing wireless RF connectivity to autho- rized devices within the area

  17. Does Global Progress on Sanitation Really Lag behind Water? An Analysis of Global Progress on Community- and Household-Level Access to Safe Water and Sanitation

    PubMed Central

    Cumming, Oliver; Elliott, Mark; Overbo, Alycia; Bartram, Jamie

    2014-01-01

    Safe drinking water and sanitation are important determinants of human health and wellbeing and have recently been declared human rights by the international community. Increased access to both were included in the Millennium Development Goals under a single dedicated target for 2015. This target was reached in 2010 for water but sanitation will fall short; however, there is an important difference in the benchmarks used for assessing global access. For drinking water the benchmark is community-level access whilst for sanitation it is household-level access, so a pit latrine shared between households does not count toward the Millennium Development Goal (MDG) target. We estimated global progress for water and sanitation under two scenarios: with equivalent household- and community-level benchmarks. Our results demonstrate that the “sanitation deficit” is apparent only when household-level sanitation access is contrasted with community-level water access. When equivalent benchmarks are used for water and sanitation, the global deficit is as great for water as it is for sanitation, and sanitation progress in the MDG-period (1990–2015) outstrips that in water. As both drinking water and sanitation access yield greater benefits at the household-level than at the community-level, we conclude that any post–2015 goals should consider a household-level benchmark for both. PMID:25502659

  18. Straits to Extinction. Integrated Magneto-Bio-Stratigraphy and Cyclostratigraphy Studies Reveal the Destructive Power of Marine Gateways

    NASA Astrophysics Data System (ADS)

    Palcu, D.; Simon, D.; da Silva, A. C.; Popov, S. V.; Golovina, L.; Krijgsman, W.

    2016-12-01

    The marine gateways are an important element in the geographic and paleogeographic architecture of oceans and seas. They influence the heat and chemical exchange between neighbouring water bodies, mixing or segregating them and influencing the climate and the ecosystems. In extreme configurations, they play a role in the onset of Salinity Crises and the formation of evaporites. However, detailed information on the sensitivity and functioning of gateways remains scarce as their geological records are poorly preserved. To counter the lack of reliable records our research focuses on the impact of the gateways on the adjacent seas. We studied marine sediments from basins that belonged to the Neogene system of seas and lakes of Eurasia (Paratethys). Integrated magneto-bio-stratigraphy and cyclostratigraphy studies in these basins have provided high-resolution correlations between the neighbouring seas within Paratethys, which, in turn, led to the identification of problematic gateway configurations. Here we focus on two such configurations: the setting that allows evaporite formation and the configuration that leads to extinction events. The gateway setting responsible for salinity crises not only leads to extinctions but also to the formation evaporites. We focus on the Badenian Salinity Crisis (BSC), an event that occurred between 13.8-13.3Ma, which is particularly interesting because it is a selective salinity crisis, happening only in some of the sub-basins of Paratethys. In this case, our initial evidence shows that the configuration requires multiple gateways that can produce water stratification and brine formation. The gateway configuration that triggers extinctions has been linked with the Badenian-Sarmatian Extinction Event (BSEE), placed at 12.65Ma. The event. that has completely destroyed the marine ecosystems of Central and Eastern Europe (with an extinction rate of 94%), has occurred in less than 10kyr and according to our numerical modelling results it

  19. Gateway to College: Lessons from Implementing a Rigorous Academic Program for At-Risk Young People

    ERIC Educational Resources Information Center

    Willard, Jacklyn Altuna; Bayes, Brian; Martinez, John

    2015-01-01

    This study reports on the implementation of Gateway to College, a program whose mission is to serve students who have dropped out of high school, or who are at risk of dropping out of high school, by allowing them to earn a high school diploma and credits toward a postsecondary degree. Gateway to College is uniquely ambitious in providing…

  20. Heliophysics Radio Observations Enabled by the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Kasper, J. C.

    2018-02-01

    This presentation reviews the scientific potential of low frequency radio imaging from space, the SunRISE radio interferometer, and the scientific value of larger future arrays in deep space and how they would benefit from the Deep Space Gateway.

  1. Efficient preparation of shuffled DNA libraries through recombination (Gateway) cloning.

    PubMed

    Lehtonen, Soili I; Taskinen, Barbara; Ojala, Elina; Kukkurainen, Sampo; Rahikainen, Rolle; Riihimäki, Tiina A; Laitinen, Olli H; Kulomaa, Markku S; Hytönen, Vesa P

    2015-01-01

    Efficient and robust subcloning is essential for the construction of high-diversity DNA libraries in the field of directed evolution. We have developed a more efficient method for the subcloning of DNA-shuffled libraries by employing recombination cloning (Gateway). The Gateway cloning procedure was performed directly after the gene reassembly reaction, without additional purification and amplification steps, thus simplifying the conventional DNA shuffling protocols. Recombination-based cloning, directly from the heterologous reassembly reaction, conserved the high quality of the library and reduced the time required for the library construction. The described method is generally compatible for the construction of DNA-shuffled gene libraries. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  2. A Life-Course Perspective on the "Gateway Hypothesis"

    ERIC Educational Resources Information Center

    Van Gundy, Karen; Rebellon, Cesar J.

    2010-01-01

    Drawing on stress and life-course perspectives and using panel data from 1,286 south Florida young adults, we assess three critical questions regarding the role of marijuana in the "gateway hypothesis." First, does teen marijuana use independently (causally) affect subsequent use of more dangerous substances? Second, if so, does that…

  3. 2. WILLITS SIGN. GATEWAY TO THE REDWOODS. WILLITS, MENDOCINO COUNTY, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. WILLITS SIGN. GATEWAY TO THE REDWOODS. WILLITS, MENDOCINO COUNTY, CALIFORNIA. LOOKING NW. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  4. 67. WILLITS SIGN. GATEWAY TO THE REDWOODS. WILLITS, MENDOCINO COUNTY, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    67. WILLITS SIGN. GATEWAY TO THE REDWOODS. WILLITS, MENDOCINO COUNTY, CALIFORNIA. LOOKING NW. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  5. Climate Change and Global Food Security: Food Access, Utilization, and the US Food System

    NASA Astrophysics Data System (ADS)

    Brown, M. E.; Antle, J. M.; Backlund, P. W.; Carr, E. R.; Easterling, W. E.; Walsh, M.; Ammann, C. M.; Attavanich, W.; Barrett, C. B.; Bellemare, M. F.; Dancheck, V.; Funk, C.; Grace, K.; Ingram, J. S. I.; Jiang, H.; Maletta, H.; Mata, T.; Murray, A.; Ngugi, M.; Ojima, D. S.; O'Neill, B. C.; Tebaldi, C.

    2015-12-01

    This paper will summarize results from the USDA report entitled 'Climate change, Global Food Security and the U.S. Food system'. The report focuses on the impact of climate change on global food security, defined as "when all people at all times have physical, social, and economic access to sufficient, safe, and nutritious food to meet their dietary needs and food preferences for an active and healthy life". The assessment brought together authors and contributors from twenty federal, academic, nongovernmental, intergovernmental, and private organizations in four countries to identify climate change effects on food security through 2100, and analyze the U.S.'s likely connections with that world. This talk will describe how climate change will likely affect food access and food utilization, and summarize how the U.S. food system contributes to global food security, and will be affected by climate change.

  6. Advances in Planetary Protection at the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Spry, J. A.; Siegel, B.; Race, M.; Rummel, J. D.; Pugel, D. E.; Groen, F. J.; Kminek, G.; Conley, C. A.; Carosso, N. J.

    2018-02-01

    Planetary protection knowledge gaps that can be addressed by science performed at the Deep Space Gateway in the areas of human health and performance, space biology, and planetary sciences that enable future exploration in deep space, at Mars, and other targets.

  7. Impact Flash Monitoring Facility on the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Needham, D. H.; Moser, D. E.; Suggs, R. M.; Cooke, W. J.; Kring, D. A.; Neal, C. R.; Fassett, C. I.

    2018-02-01

    Cameras mounted to the Deep Space Gateway exterior will detect flashes caused by impacts on the lunar surface. Observed flashes will help constrain the current lunar impact flux and assess hazards faced by crews living and working in cislunar space.

  8. Access to the Mars Global Surveyor Data Through the Planetary Image Atlas

    NASA Technical Reports Server (NTRS)

    Ivanov, A. B.; Duxbury, E. D.; LaVoie, S. K.; McAuley, M.; Woncik, P. J.

    2002-01-01

    We will present our latest results in providing access to the Mars Global Surveyor Data through the Planetary Image Atlas. This work is a prototype for future Internet based data distribution systems. Additional information is contained in the original extended abstract.

  9. Cultural models of self and social class disparities at organizational gateways and pathways.

    PubMed

    Townsend, Sarah Sm; Truong, Mindy

    2017-12-01

    Attaining a college degree has traditionally been assumed to be key to upward social and professional mobility. However, college graduates from working-class backgrounds achieve less career success in professional, white-collar workplaces compared to those from middle-class backgrounds. Using a cultural models approach, we examine how the independent cultural beliefs and practices promoted by professional organizations disadvantage people from working-class backgrounds, who espouse interdependent beliefs and practices. Our review illustrates how this disadvantage can manifest in two ways. First, despite relative equality in objective qualifications, it can occur at organizational gateways (e.g., interview and hiring decisions). Second, even after people from working-class backgrounds gain access to an organization, it can occur along organizational pathways (e.g., performance evaluations and assignment to high-profile tasks). Copyright © 2017. Published by Elsevier Ltd.

  10. Amplified North Atlantic warming in the late Pliocene by changes in Arctic gateways

    DOE PAGES

    Otto-Bliesner, Bette L.; Jahn, Alexandra; Feng, Ran; ...

    2016-12-26

    Under previous reconstructions of late Pliocene boundary conditions, climate models have failed to reproduce the warm sea surface temperatures reconstructed in the North Atlantic. Using a reconstruction of mid-Piacenzian paleogeography that has the Bering Strait and Canadian Arctic Archipelago Straits closed, however, improves the simulation of the proxy-indicated warm sea surface temperatures in the North Atlantic in the Community Climate System Model. We find that the closure of these small Arctic gateways strengthens the Atlantic Meridional Overturning Circulation, by inhibiting freshwater transport from the Pacific to the Arctic Ocean and from the Arctic Ocean to the Labrador Sea, leading tomore » warmer sea surface temperatures in the North Atlantic. In conclusion, this indicates that the state of the Arctic gateways may influence the sensitivity of the North Atlantic climate in complex ways, and better understanding of the state of these Arctic gateways for past time periods is needed.« less

  11. Relevance of Google-customized search engine vs. CISMeF quality-controlled health gateway.

    PubMed

    Gehanno, Jean-François; Kerdelhue, Gaétan; Sakji, Saoussen; Massari, Philippe; Joubert, Michel; Darmoni, Stéfan J

    2009-01-01

    CISMeF (acronym for Catalog and Index of French Language Health Resources on the Internet) is a quality-controlled health gateway conceived to catalog and index the most important and quality-controlled sources of institutional health information in French. The goal of this study is to compare the relevance of results provided by this gateway from a small set of documents selected and described by human experts to those provided by a search engine from a large set of automatically indexed and ranked resources. The Google-Customized search engine (CSE) was used. The evaluation was made using the 10th first results of 15 queries and two blinded physician evaluators. There was no significant difference between the relevance of information retrieval in CISMeF and Google CSE. In conclusion, automatic indexing does not lead to lower relevance than a manual MeSH indexing and may help to cope with the increasing number of references to be indexed in a controlled health quality gateway.

  12. Theater gateway closure: a strategic level barricade

    DTIC Science & Technology

    that at the strategic level the effects are based on the economic and diplomatic elements of the national power, affecting proportionally sustainment...Seven months of detrimental political implications, expensive effects on military operations, and strategic level barricades during 2011 and 2012 in...logistical planners at the strategic level can anticipate or mitigate the effects of a theater gateway closure on military operations. Through two

  13. Multi-Modal Traveler Information System - Gateway Phased Implementation Plan

    DOT National Transportation Integrated Search

    1997-11-25

    The purpose of this working paper is to provide the main concepts and elements that need to be addressed in the overall implementation of the Gateway, both the Initial Phase and the Ultimate Phase. This working paper addresses these concepts and elem...

  14. Fluoroscopy guided percutaneous renal access in prone position

    PubMed Central

    Sharma, Gyanendra R; Maheshwari, Pankaj N; Sharma, Anshu G; Maheshwari, Reeta P; Heda, Ritwik S; Maheshwari, Sakshi P

    2015-01-01

    Percutaneous nephrolithotomy is a very commonly done procedure for management of renal calculus disease. Establishing a good access is the first and probably the most crucial step of this procedure. A proper access is the gateway to success. However, this crucial step has the steepest learning curve for, in a fluoroscopy guided access, it involves visualizing a three dimensional anatomy on a two dimensional fluoroscopy screen. This review describes the anatomical basis of the renal access. It provides a literature review of all aspects of percutaneous renal access along with the advances that have taken place in this field over the years. The article describes a technique to determine the site of skin puncture, the angle and depth of puncture using a simple mathematical principle. It also reviews the common problems faced during the process of puncture and dilatation and describes the ways to overcome them. The aim of this article is to provide the reader a step by step guide for percutaneous renal access. PMID:25789297

  15. Constrained Surface-Level Gateway Placement for Underwater Acoustic Wireless Sensor Networks

    NASA Astrophysics Data System (ADS)

    Li, Deying; Li, Zheng; Ma, Wenkai; Chen, Hong

    One approach to guarantee the performance of underwater acoustic sensor networks is to deploy multiple Surface-level Gateways (SGs) at the surface. This paper addresses the connected (or survivable) Constrained Surface-level Gateway Placement (C-SGP) problem for 3-D underwater acoustic sensor networks. Given a set of candidate locations where SGs can be placed, our objective is to place minimum number of SGs at a subset of candidate locations such that it is connected (or 2-connected) from any USN to the base station. We propose a polynomial time approximation algorithm for the connected C-SGP problem and survivable C-SGP problem, respectively. Simulations are conducted to verify our algorithms' efficiency.

  16. Signaling gateway molecule pages—a data model perspective

    PubMed Central

    Dinasarapu, Ashok Reddy; Saunders, Brian; Ozerlat, Iley; Azam, Kenan; Subramaniam, Shankar

    2011-01-01

    Summary: The Signaling Gateway Molecule Pages (SGMP) database provides highly structured data on proteins which exist in different functional states participating in signal transduction pathways. A molecule page starts with a state of a native protein, without any modification and/or interactions. New states are formed with every post-translational modification or interaction with one or more proteins, small molecules or class molecules and with each change in cellular location. State transitions are caused by a combination of one or more modifications, interactions and translocations which then might be associated with one or more biological processes. In a characterized biological state, a molecule can function as one of several entities or their combinations, including channel, receptor, enzyme, transcription factor and transporter. We have also exported SGMP data to the Biological Pathway Exchange (BioPAX) and Systems Biology Markup Language (SBML) as well as in our custom XML. Availability: SGMP is available at www.signaling-gateway.org/molecule. Contact: shankar@ucsd.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:21505029

  17. Low-Cost Planetary Missions Enabled by the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Berinstain, A.; Richards, R. D.

    2018-02-01

    The authors will present options for discussion among participants of how low-cost lunar and planetary missions using the Moon Express family of spacecraft can be enabled by the presence of the Deep Space Gateway.

  18. GEOCAB Portal: A gateway for discovering and accessing capacity building resources in Earth Observation

    NASA Astrophysics Data System (ADS)

    Desconnets, Jean-Christophe; Giuliani, Gregory; Guigoz, Yaniss; Lacroix, Pierre; Mlisa, Andiswa; Noort, Mark; Ray, Nicolas; Searby, Nancy D.

    2017-02-01

    The discovery of and access to capacity building resources are often essential to conduct environmental projects based on Earth Observation (EO) resources, whether they are Earth Observation products, methodological tools, techniques, organizations that impart training in these techniques or even projects that have shown practical achievements. Recognizing this opportunity and need, the European Commission through two FP7 projects jointly with the Group on Earth Observations (GEO) teamed up with the Committee on Earth observation Satellites (CEOS). The Global Earth Observation CApacity Building (GEOCAB) portal aims at compiling all current capacity building efforts on the use of EO data for societal benefits into an easily updateable and user-friendly portal. GEOCAB offers a faceted search to improve user discovery experience with a fully interactive world map with all inventoried projects and activities. This paper focuses on the conceptual framework used to implement the underlying platform. An ISO19115 metadata model associated with a terminological repository are the core elements that provide a semantic search application and an interoperable discovery service. The organization and the contribution of different user communities to ensure the management and the update of the content of GEOCAB are addressed.

  19. Three-Dimensional (3-D) Printing: A Cost-Effective Solution for Improving Global Accessibility to Prostheses.

    PubMed

    Silva, Kyle; Rand, Stephanie; Cancel, David; Chen, Yuxi; Kathirithamby, Rani; Stern, Michelle

    2015-12-01

    The lack of access to prostheses is a global problem, partially caused by the high cost associated with the current manufacturing process. Three-dimensional printing is gaining use in the medical field, and one such area is prosthetics. In addition to using cost-effective materials, this technology allows for rapid prototyping, making it an efficient solution for the development of affordable prostheses. If the rehabilitation medicine community embraces this novel technology, we can help alleviate the global disparity of access to prostheses. Copyright © 2015 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  20. Global review of open access risk assessment software packages valid for global or continental scale analysis

    NASA Astrophysics Data System (ADS)

    Daniell, James; Simpson, Alanna; Gunasekara, Rashmin; Baca, Abigail; Schaefer, Andreas; Ishizawa, Oscar; Murnane, Rick; Tijssen, Annegien; Deparday, Vivien; Forni, Marc; Himmelfarb, Anne; Leder, Jan

    2015-04-01

    Over the past few decades, a plethora of open access software packages for the calculation of earthquake, volcanic, tsunami, storm surge, wind and flood have been produced globally. As part of the World Bank GFDRR Review released at the Understanding Risk 2014 Conference, over 80 such open access risk assessment software packages were examined. Commercial software was not considered in the evaluation. A preliminary analysis was used to determine whether the 80 models were currently supported and if they were open access. This process was used to select a subset of 31 models that include 8 earthquake models, 4 cyclone models, 11 flood models, and 8 storm surge/tsunami models for more detailed analysis. By using multi-criteria analysis (MCDA) and simple descriptions of the software uses, the review allows users to select a few relevant software packages for their own testing and development. The detailed analysis evaluated the models on the basis of over 100 criteria and provides a synopsis of available open access natural hazard risk modelling tools. In addition, volcano software packages have since been added making the compendium of risk software tools in excess of 100. There has been a huge increase in the quality and availability of open access/source software over the past few years. For example, private entities such as Deltares now have an open source policy regarding some flood models (NGHS). In addition, leaders in developing risk models in the public sector, such as Geoscience Australia (EQRM, TCRM, TsuDAT, AnuGA) or CAPRA (ERN-Flood, Hurricane, CRISIS2007 etc.), are launching and/or helping many other initiatives. As we achieve greater interoperability between modelling tools, we will also achieve a future wherein different open source and open access modelling tools will be increasingly connected and adapted towards unified multi-risk model platforms and highly customised solutions. It was seen that many software tools could be improved by enabling user

  1. Functional design for U.S. Coast Guard intelligent communications gateway

    DOT National Transportation Integrated Search

    1995-02-27

    This report documents the functional design of hardware and software components necessary to satisfy the U.S. Coast Guard (USCG) requirements identified for an Intelligent Gateway (IG). The IG will transfer messages from USCG shoreside networks to tr...

  2. MaizeGDB: Global support for maize research through open access information [abstract

    USDA-ARS?s Scientific Manuscript database

    MaizeGDB is the open-access global repository for maize genetic and genomic information – from single genes that determine nutritional quality to whole genome-scale data for complex traits including yield and drought tolerance. The data and tools at MaizeGDB enable researchers from Ethiopia to Ghan...

  3. A simple Gateway-assisted construction system of TALEN genes for plant genome editing.

    PubMed

    Kusano, Hiroaki; Onodera, Hitomi; Kihira, Miho; Aoki, Hiromi; Matsuzaki, Hikaru; Shimada, Hiroaki

    2016-07-25

    TALEN is an artificial nuclease being applied for sequence-specific genome editing. For the plant genome editing, a pair of TALEN genes is expressed in the cells, and a binary plasmid for Agrobacterium-mediated transformation should be assembled. We developed a novel procedure using the Gateway-assisted plasmids, named Emerald-Gateway TALEN system. We constructed entry vectors, pPlat plasmids, for construction of a desired TALEN gene using Platinum Gate TALEN kit. We also created destination plasmid, pDual35SGw1301, which allowed two TALEN genes to both DNA strands to recruit using Gateway technology. Resultant TALEN genes were evaluated by the single-strand annealing (SSA) assay in E. coli cells. By this assay, the TALENs recognized the corresponding targets in the divided luciferase gene, and induced a specific recombination to generate an active luciferase gene. Using the TALEN genes constructed, we created a transformant potato cells in which a site-specific mutation occurred at the target site of the GBSS gene. This suggested that our system worked effectively and was applicable as a convenient tool for the plant genome editing.

  4. The Deep Space Gateway: The Next Stepping Stone to Mars

    NASA Astrophysics Data System (ADS)

    Cassady, R. J.; Carberry, C.; Cichan, T.

    2018-02-01

    Human missions to Mars will benefit from precursor missions such as the Deep Space Gateway (DSG) that achieve important science and human health and safety milestones. The DSG can perform lunar science and prepare for future Mars mission science.

  5. Can Internet Access Growth Help Reduce the Global Burden Of Noncommunicable Diseases?

    PubMed Central

    Kohler, Stefan

    2013-01-01

    Noncommunicable diseases, such as cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes, are currently the leading causes of death in several regions of the world. The continuing fast increase in the global burden of noncommunicable diseases is accompanied by a speedy worldwide internet access growth. The worldwide number of internet users has doubled over the past five years. As the internet can make the access to information on a healthy lifestyle and disease prevention activities easier, internet access growth may help to promote good health. Against this background, I discuss the roles the internet and access to information can play in health promotion. I also present an open access web portal on local prevention and health promotion activities. It was initiated by two German states to link health information from disparate sources and to organize this information in a user-friendly way. The web portal focuses on reducing preventable lifestyle-related risk factors associated with noncommunicable diseases, including physical inactivity, unhealthy diet, tobacco use, and the harmful use of alcohol. This local initiative has the potential for scaling up and can serve as a blueprint for other areas that have or will acquire internet access. PMID:23923103

  6. Providing Access to a Diverse Set of Global Reanalysis Dataset Collections

    NASA Astrophysics Data System (ADS)

    Schuster, D.; Worley, S. J.

    2015-12-01

    The National Center for Atmospheric Research (NCAR) Research Data Archive (RDA, http://rda.ucar.edu) provides open access to a variety of global reanalysis dataset collections to support atmospheric and related sciences research worldwide. These include products from the European Centre for Medium-Range Weather Forecasts (ECMWF), Japan Meteorological Agency (JMA), National Centers for Environmental Prediction (NCEP), National Oceanic and Atmospheric Administration (NOAA), and NCAR.All RDA hosted reanalysis collections are freely accessible to registered users through a variety of methods. Standard access methods include traditional browser and scripted HTTP file download. Enhanced downloads are available through the Globus GridFTP "fire and forget" data transfer service, which provides an efficient, reliable, and preferred alternative to traditional HTTP-based methods. For those that favor interoperable access using compatible tools, the Unidata THREDDS Data server provides remote access to complete reanalysis collections by virtual dataset aggregation "files". Finally, users can request data subsets and format conversions to be prepared for them through web interface form requests or web service API batch requests. This approach uses NCAR HPC and central file systems to effectively prepare products from the high-resolution and very large reanalyses archives. The presentation will include a detailed inventory of all RDA reanalysis dataset collection holdings, and highlight access capabilities to these collections through use case examples.

  7. The Einstein Genome Gateway using WASP - a high throughput multi-layered life sciences portal for XSEDE.

    PubMed

    Golden, Aaron; McLellan, Andrew S; Dubin, Robert A; Jing, Qiang; O Broin, Pilib; Moskowitz, David; Zhang, Zhengdong; Suzuki, Masako; Hargitai, Joseph; Calder, R Brent; Greally, John M

    2012-01-01

    Massively-parallel sequencing (MPS) technologies and their diverse applications in genomics and epigenomics research have yielded enormous new insights into the physiology and pathophysiology of the human genome. The biggest hurdle remains the magnitude and diversity of the datasets generated, compromising our ability to manage, organize, process and ultimately analyse data. The Wiki-based Automated Sequence Processor (WASP), developed at the Albert Einstein College of Medicine (hereafter Einstein), uniquely manages to tightly couple the sequencing platform, the sequencing assay, sample metadata and the automated workflows deployed on a heterogeneous high performance computing cluster infrastructure that yield sequenced, quality-controlled and 'mapped' sequence data, all within the one operating environment accessible by a web-based GUI interface. WASP at Einstein processes 4-6 TB of data per week and since its production cycle commenced it has processed ~ 1 PB of data overall and has revolutionized user interactivity with these new genomic technologies, who remain blissfully unaware of the data storage, management and most importantly processing services they request. The abstraction of such computational complexity for the user in effect makes WASP an ideal middleware solution, and an appropriate basis for the development of a grid-enabled resource - the Einstein Genome Gateway - as part of the Extreme Science and Engineering Discovery Environment (XSEDE) program. In this paper we discuss the existing WASP system, its proposed middleware role, and its planned interaction with XSEDE to form the Einstein Genome Gateway.

  8. The Monash Portal: More Than Just a Virtual Gateway.

    ERIC Educational Resources Information Center

    Kennedy, David; Webster, Len; Benson, Robyn; James, Di; Bailey, Nathan

    The My Monash Portal (Portal) at Monash University (Australia) provides a virtual gateway to support student-centered flexible learning by coordinating several of the university's key resources to meet the needs of students and staff. The Portal is intended to help deliver innovative learning programs, foster opportunities to undertake research,…

  9. Key Challenges for Life Science Payloads on the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Anthony, J. H.; Niederwieser, T.; Zea, L.; Stodieck, L.

    2018-02-01

    Compared to ISS, Deep Space Gateway life science payloads will be challenged by deep space radiation and non-continuous habitation. The impacts of these two differences on payload requirements, design, and operations are discussed.

  10. Earth Observation and Science: Monitoring Vegetation Dynamics from Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Knyazikhin, Y.; Park, T.; Hu, B.

    2018-02-01

    Retrieving diurnal courses of sunlit (SLAI) and shaded (ShLAI) leaf area indices, fraction of photosynthetically active radiation (PAR) absorbed by vegetation (FPAR), and Normalized Difference Vegetation Index (NDVI) from Deep Space Gateway data.

  11. Network Computing Infrastructure to Share Tools and Data in Global Nuclear Energy Partnership

    NASA Astrophysics Data System (ADS)

    Kim, Guehee; Suzuki, Yoshio; Teshima, Naoya

    CCSE/JAEA (Center for Computational Science and e-Systems/Japan Atomic Energy Agency) integrated a prototype system of a network computing infrastructure for sharing tools and data to support the U.S. and Japan collaboration in GNEP (Global Nuclear Energy Partnership). We focused on three technical issues to apply our information process infrastructure, which are accessibility, security, and usability. In designing the prototype system, we integrated and improved both network and Web technologies. For the accessibility issue, we adopted SSL-VPN (Security Socket Layer-Virtual Private Network) technology for the access beyond firewalls. For the security issue, we developed an authentication gateway based on the PKI (Public Key Infrastructure) authentication mechanism to strengthen the security. Also, we set fine access control policy to shared tools and data and used shared key based encryption method to protect tools and data against leakage to third parties. For the usability issue, we chose Web browsers as user interface and developed Web application to provide functions to support sharing tools and data. By using WebDAV (Web-based Distributed Authoring and Versioning) function, users can manipulate shared tools and data through the Windows-like folder environment. We implemented the prototype system in Grid infrastructure for atomic energy research: AEGIS (Atomic Energy Grid Infrastructure) developed by CCSE/JAEA. The prototype system was applied for the trial use in the first period of GNEP.

  12. How accessible are coral reefs to people? A global assessment based on travel time.

    PubMed

    Maire, Eva; Cinner, Joshua; Velez, Laure; Huchery, Cindy; Mora, Camilo; Dagata, Stephanie; Vigliola, Laurent; Wantiez, Laurent; Kulbicki, Michel; Mouillot, David

    2016-04-01

    The depletion of natural resources has become a major issue in many parts of the world, with the most accessible resources being most at risk. In the terrestrial realm, resource depletion has classically been related to accessibility through road networks. In contrast, in the marine realm, the impact on living resources is often framed into the Malthusian theory of human density around ecosystems. Here, we develop a new framework to estimate the accessibility of global coral reefs using potential travel time from the nearest human settlement or market. We show that 58% of coral reefs are located < 30 min from the nearest human settlement. We use a case study from New Caledonia to demonstrate that travel time from the market is a strong predictor of fish biomass on coral reefs. We also highlight a relative deficit of protection on coral reef areas near people, with disproportional protection on reefs far from people. This suggests that conservation efforts are targeting low-conflict reefs or places that may already be receiving de facto protection due to their isolation. Our global assessment of accessibility in the marine realm is a critical step to better understand the interplay between humans and resources. © 2016 John Wiley & Sons Ltd/CNRS.

  13. The SPAN cookbook: A practical guide to accessing SPAN

    NASA Technical Reports Server (NTRS)

    Mason, Stephanie; Tencati, Ronald D.; Stern, David M.; Capps, Kimberly D.; Dorman, Gary; Peters, David J.

    1990-01-01

    This is a manual for remote users who wish to send electronic mail messages from the Space Physics Analysis Network (SPAN) to scientific colleagues on other computer networks and vice versa. In several instances more than one gateway has been included for the same network. Users are provided with an introduction to each network listed with helpful details about accessing the system and mail syntax examples. Also included is information on file transfers, remote logins, and help telephone numbers.

  14. Lunar Volatile System Dynamics: Observations Enabled by the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Honniball, C. I.; Lucey, P. G.; Petro, N.; Hurley, D.; Farrell, W.

    2018-02-01

    A UV spectrometer-imager and IR spectrometer are proposed to solve questions regarding the lunar volatile system. The instrument takes advantage of highly elliptical orbits and the thermal management system of the Deep Space Gateway.

  15. VIEWCACHE: An incremental pointer-based access method for autonomous interoperable databases

    NASA Technical Reports Server (NTRS)

    Roussopoulos, N.; Sellis, Timos

    1993-01-01

    One of the biggest problems facing NASA today is to provide scientists efficient access to a large number of distributed databases. Our pointer-based incremental data base access method, VIEWCACHE, provides such an interface for accessing distributed datasets and directories. VIEWCACHE allows database browsing and search performing inter-database cross-referencing with no actual data movement between database sites. This organization and processing is especially suitable for managing Astrophysics databases which are physically distributed all over the world. Once the search is complete, the set of collected pointers pointing to the desired data are cached. VIEWCACHE includes spatial access methods for accessing image datasets, which provide much easier query formulation by referring directly to the image and very efficient search for objects contained within a two-dimensional window. We will develop and optimize a VIEWCACHE External Gateway Access to database management systems to facilitate database search.

  16. VIEWCACHE: An incremental pointer-based access method for autonomous interoperable databases

    NASA Technical Reports Server (NTRS)

    Roussopoulos, N.; Sellis, Timos

    1992-01-01

    One of biggest problems facing NASA today is to provide scientists efficient access to a large number of distributed databases. Our pointer-based incremental database access method, VIEWCACHE, provides such an interface for accessing distributed data sets and directories. VIEWCACHE allows database browsing and search performing inter-database cross-referencing with no actual data movement between database sites. This organization and processing is especially suitable for managing Astrophysics databases which are physically distributed all over the world. Once the search is complete, the set of collected pointers pointing to the desired data are cached. VIEWCACHE includes spatial access methods for accessing image data sets, which provide much easier query formulation by referring directly to the image and very efficient search for objects contained within a two-dimensional window. We will develop and optimize a VIEWCACHE External Gateway Access to database management systems to facilitate distributed database search.

  17. Compliance Patterns and Utilization of e-Health for Glucose Monitoring: Standalone Internet Gateway and Tablet Device.

    PubMed

    Rho, Mi Jung; Kim, Hun-Sung; Yoon, Kun-Ho; Choi, In Young

    2017-04-01

    Knowledge regarding compliance patterns and service utilization in e-health is important for the development of effective services. To develop proper e-health, the characteristics of compliance patterns and utilization of e-health should be studied. We studied these for glucose monitoring of diabetic patients from primary clinics. Data were collected from 160 outpatients who participated in e-health for glucose monitoring funded by the Korean government. Specifically, this study focused on two device types: a standalone Internet gateway and a tablet device. The SPSS 18.0 software was used for statistical analyses of demographic characteristics, survival data, and Cox proportional hazards regression model. Standalone Internet gateway users demonstrated a more stable compliance pattern than did tablet device users. The compliance rate differed according to the device type. Typically, compliance decreases considerably around 8 months. In these results, standalone Internet gateway users utilized the service for longer periods than tablet device users. Gateway type and location also influenced utilization (p < 0.05). The service should be designed according to the device type to develop appropriate service models. Thus, service designers should understand the different characteristics of service devices. This study provides insight into compliance patterns and utilization to develop appropriate service models and service interventions depending on the device.

  18. Exploration of Near-Earth Objects from the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Dunham, D. W.; Stakkestad, K.; Vedder, P.; McAdams, J.; Horsewood, J.; Genova, A. L.

    2018-02-01

    The paper will show how clever use of orbital dynamics can lower delta-V costs to enable scientifically interesting missions. The high-energy Deep Space Gateway orbits can be used to reach NEOs, a trans node for crews, or to deploy small sats. Examples are given.

  19. NOAASIS Gateway - NOAA Satellite Information System (NOAASIS); Office of

    Science.gov Websites

    Satellite and Product Operations » DOC » NOAA » NESDIS » NOAASIS NOAA Satellite Information System NOAASIS Gateway The NOAA Satellite Information System provides essential information for satellite direct readout station operators and users of NOAA environmental satellite data. While the emphasis is on

  20. A Planetary Defense Gateway for Smart Discovery of relevant Information for Decision Support

    NASA Technical Reports Server (NTRS)

    Bambacus, Myra; Yang, Chaowei Phil; Leung, Ronald Y.; Barbee, Brent; Nuth, Joseph A.; Seery, Bernard; Jiang, Yongyao; Qin, Han; Li, Yun; Yu, Manzhu; hide

    2017-01-01

    A Planetary Defense Gateway for Smart Discovery of relevant Information for Decision Support presentation discussing background, framework architecture, current results, ongoing research, conclusions.

  1. Distributed Earth observation data integration and on-demand services based on a collaborative framework of geospatial data service gateway

    NASA Astrophysics Data System (ADS)

    Xie, Jibo; Li, Guoqing

    2015-04-01

    Earth observation (EO) data obtained by air-borne or space-borne sensors has the characteristics of heterogeneity and geographical distribution of storage. These data sources belong to different organizations or agencies whose data management and storage methods are quite different and geographically distributed. Different data sources provide different data publish platforms or portals. With more Remote sensing sensors used for Earth Observation (EO) missions, different space agencies have distributed archived massive EO data. The distribution of EO data archives and system heterogeneity makes it difficult to efficiently use geospatial data for many EO applications, such as hazard mitigation. To solve the interoperable problems of different EO data systems, an advanced architecture of distributed geospatial data infrastructure is introduced to solve the complexity of distributed and heterogeneous EO data integration and on-demand processing in this paper. The concept and architecture of geospatial data service gateway (GDSG) is proposed to build connection with heterogeneous EO data sources by which EO data can be retrieved and accessed with unified interfaces. The GDSG consists of a set of tools and service to encapsulate heterogeneous geospatial data sources into homogenous service modules. The GDSG modules includes EO metadata harvesters and translators, adaptors to different type of data system, unified data query and access interfaces, EO data cache management, and gateway GUI, etc. The GDSG framework is used to implement interoperability and synchronization between distributed EO data sources with heterogeneous architecture. An on-demand distributed EO data platform is developed to validate the GDSG architecture and implementation techniques. Several distributed EO data achieves are used for test. Flood and earthquake serves as two scenarios for the use cases of distributed EO data integration and interoperability.

  2. The emergence of a global right to health norm--the unresolved case of universal access to quality emergency obstetric care.

    PubMed

    Hammonds, Rachel; Ooms, Gorik

    2014-02-27

    The global response to HIV suggests the potential of an emergent global right to health norm, embracing shared global responsibility for health, to assist policy communities in framing the obligations of the domestic state and the international community. Our research explores the extent to which this global right to health norm has influenced the global policy process around maternal health rights, with a focus on universal access to emergency obstetric care. In examining the extent to which arguments stemming from a global right to health norm have been successful in advancing international policy on universal access to emergency obstetric care, we looked at the period from 1985 to 2013 period. We adopted a qualitative case study approach applying a process-tracing methodology using multiple data sources, including an extensive literature review and limited key informant interviews to analyse the international policy agenda setting process surrounding maternal health rights, focusing on emergency obstetric care. We applied John Kingdon's public policy agenda setting streams model to analyse our data. Kingdon's model suggests that to succeed as a mobilising norm, the right to health could work if it can help bring the problem, policy and political streams together, as it did with access to AIDS treatment. Our analysis suggests that despite a normative grounding in the right to health, prioritisation of the specific maternal health entitlements remains fragmented. Despite United Nations recognition of maternal mortality as a human rights issue, the relevant policy communities have not yet managed to shift the policy agenda to prioritise the global right to health norm of shared responsibility for realising access to emergency obstetric care. The experience of HIV advocates in pushing for global solutions based on right to health principles, including participation, solidarity and accountability; suggest potential avenues for utilising right to health based

  3. Laser-Assisted Wire Additive Manufacturing System for the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Foster, B. D.; Matthews, B.

    2018-02-01

    Investigation on the Deep Space Gateway will involve experiments/operations inside pressurized modules. Support for those experiments may necessitate a means to fabricate and repair required articles. This capability can be provided through an additive manufacturing (AM) system.

  4. Increasing global accessibility and understanding of water column sonar data

    NASA Astrophysics Data System (ADS)

    Wall, C.; Anderson, C.; Mesick, S.; Parsons, A. R.; Boyer, T.; McLean, S. J.

    2016-02-01

    Active acoustic (sonar) technology is of increasing importance for research examining the water column. NOAA uses water column sonar data to map acoustic properties from the ocean surface to the seafloor - from bubbles to biology to bottom. Scientific echosounders aboard fishery survey vessels are used to estimate biomass, measure fish school morphology, and characterize habitat. These surveys produce large volumes of data that are costly and difficult to maintain due to their size, complexity, and proprietary format that require specific software and extensive knowledge. However, through proper management they can deliver valuable information beyond their original collection purpose. In order to maximize the benefit to the public, the data must be easily discoverable and accessible. Access to ancillary data is also needed for complete environmental context and ecosystem assessment. NOAA's National Centers for Environmental Information, in partnership with NOAA's National Marine Fisheries Service and the University of Colorado, created a national archive for the stewardship and distribution of water column sonar data collected on NOAA and academic vessels. A web-based access page allows users to query the metadata and access the raw sonar data. Visualization products being developed allow researchers and the public to understand the quality and content of large volumes of archived data more easily. Such products transform the complex data into a digestible image or graphic and are highly valuable for a broad audience of varying backgrounds. Concurrently collected oceanographic data and bathymetric data are being integrated into the data access web page to provide an ecosystem-wide understanding of the area ensonified. Benefits of the archive include global access to an unprecedented nationwide dataset and the increased potential for researchers to address cross-cutting scientific questions to advance the field of marine ecosystem acoustics.

  5. Lunar Science Enabled by the Deep Space Gateway and PHASR Rover

    NASA Astrophysics Data System (ADS)

    Bakambu, J. N.; Shaw, A.; Fulford, P.; Osinski, G.; Bourassa, M.; Rehmatullah, F.; Zanetti, M.; Rembala, R.

    2018-02-01

    The Deep Space Gateway will be a tremendous boon to lunar surface science. It will enable the PHASR Rover, a concept for a Canadian rover system, with international contributions and the goal of sample acquisition and lunar surface science.

  6. Design on intelligent gateway technique in home network

    NASA Astrophysics Data System (ADS)

    Hu, Zhonggong; Feng, Xiancheng

    2008-12-01

    Based on digitization, multimedia, mobility, wide band, real-time interaction and so on,family networks, because can provide diverse and personalized synthesis service in information, correspondence work, entertainment, education and health care and so on, are more and more paid attention by the market. The family network product development has become the focus of the related industry. In this paper,the concept of the family network and the overall reference model of the family network are introduced firstly.Then the core techniques and the correspondence standard related with the family network are proposed.The key analysis is made for the function of family gateway, the function module of the software,the key technologies to client side software architecture and the trend of development of the family network entertainment seeing and hearing service and so on. Product present situation of the family gateway and the future trend of development, application solution of the digital family service are introduced. The development of the family network product bringing about the digital family network industry is introduced finally.It causes the development of software industries,such as communication industry,electrical appliances industry, computer and game and so on.It also causes the development of estate industry.

  7. SCORPION II persistent surveillance system with universal gateway

    NASA Astrophysics Data System (ADS)

    Coster, Michael; Chambers, Jonathan; Brunck, Albert

    2009-05-01

    This paper addresses improvements and benefits derived from the next generation Northrop Grumman SCORPION II family of persistent surveillance and target recognition systems produced by the Xetron campus in Cincinnati, Ohio. SCORPION II reduces the size, weight, and cost of all SCORPION components in a flexible, field programmable system that is easier to conceal, backward compatible, and enables integration of over forty Unattended Ground Sensor (UGS) and camera types from a variety of manufacturers, with a modular approach to supporting multiple Line of Sight (LOS) and Beyond Line of Sight (BLOS) communications interfaces. Since 1998 Northrop Grumman has been integrating best in class sensors with its proven universal modular Gateway to provide encrypted data exfiltration to Common Operational Picture (COP) systems and remote sensor command and control. In addition to being fed to COP systems, SCORPION and SCORPION II data can be directly processed using a common sensor status graphical user interface (GUI) that allows for viewing and analysis of images and sensor data from up to seven hundred SCORPION system Gateways on single or multiple displays. This GUI enables a large amount of sensor data and imagery to be used for actionable intelligence as well as remote sensor command and control by a minimum number of analysts.

  8. The Gateway Paper--stewardship and governance in the health sector in Pakistan.

    PubMed

    Nishtar, Sania

    2006-12-01

    As an opening for a dialogue on health reforms in the country, the Gateway Paper places emphasis on strengthening the stewardship function of mandated State agencies in Pakistan with particular attention to two key areas. Firstly, greater emphasis on a stewardship role for the Ministry and departments of health in the context of inter-sectoral scope of health and secondly, a stronger role for the State agencies as regulators of healthcare within the country. The Gateway Paper envisages that the role of State agencies will become more critical as new models of financing health and delivering services are structured given that these entail regulation of private sector providers, providing oversight for ensuring a system for ongoing education and implementation of frameworks for public-private partnerships. The Gateway Paper refers to stewardship with reference to analysis and overview of health policies within the country, their relationship with evidence, their follow-up into planning and finally their implementation. The Paper also provides an insight into policies from a process-related as well as content and program related perspectives. In doing so a number of questions relating to the evidence and policy disconnect; issues at strategic and operational levels of planning, and governance-related impediments to program implementation have been discussed and a viewpoint articulated on an approach to addressing these challenges.

  9. Wireless access to a pharmaceutical database: A demonstrator for data driven Wireless Application Protocol applications in medical information processing

    PubMed Central

    Hansen, Michael Schacht

    2001-01-01

    Background The Wireless Application Protocol technology implemented in newer mobile phones has built-in facilities for handling much of the information processing needed in clinical work. Objectives To test a practical approach we ported a relational database of the Danish pharmaceutical catalogue to Wireless Application Protocol using open source freeware at all steps. Methods We used Apache 1.3 web software on a Linux server. Data containing the Danish pharmaceutical catalogue were imported from an ASCII file into a MySQL 3.22.32 database using a Practical Extraction and Report Language script for easy update of the database. Data were distributed in 35 interrelated tables. Each pharmaceutical brand name was given its own card with links to general information about the drug, active substances, contraindications etc. Access was available through 1) browsing therapeutic groups and 2) searching for a brand name. The database interface was programmed in the server-side scripting language PHP3. Results A free, open source Wireless Application Protocol gateway to a pharmaceutical catalogue was established to allow dial-in access independent of commercial Wireless Application Protocol service providers. The application was tested on the Nokia 7110 and Ericsson R320s cellular phones. Conclusions We have demonstrated that Wireless Application Protocol-based access to a dynamic clinical database can be established using open source freeware. The project opens perspectives for a further integration of Wireless Application Protocol phone functions in clinical information processing: Global System for Mobile communication telephony for bilateral communication, asynchronous unilateral communication via e-mail and Short Message Service, built-in calculator, calendar, personal organizer, phone number catalogue and Dictaphone function via answering machine technology. An independent Wireless Application Protocol gateway may be placed within hospital firewalls, which may be an

  10. GATEWAY Report Brief: Exterior Lighting at Princeton University

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    Summary of GATEWAY report focuses on four exterior solid-state lighting projects that have been completed at Princeton since 2008, when the University adopted a comprehensive sustainability plan. Through these initial projects – which include a parking garage, a pedestrian path, and two parking lot installations – the school’s facilities engineering staff learned important lessons about SSL technology and gained experience in dealing with the rapidly changing landscape of lighting manufacturers and their suppliers.

  11. Phloem-limited reoviruses universally induce sieve element hyperplasia and more flexible gateways, providing more channels for their movement in plants.

    PubMed

    Lv, Ming-Fang; Xie, Li; Song, Xi-Jiao; Hong, Jian; Mao, Qian-Zhuo; Wei, Tai-Yun; Chen, Jian-Ping; Zhang, Heng-Mu

    2017-11-28

    Virion distribution and ultrastructural changes induced by the infection of maize or rice with four different reoviruses were examined. Rice black streaked dwarf virus (RBSDV, genus Fijivirus), Rice ragged stunt virus (RRSV, genus Oryzavirus), and Rice gall dwarf virus (RGDV, genus Phytoreovirus) were all phloem-limited and caused cellular hyperplasia in the phloem resulting in tumors or vein swelling and modifying the cellular arrangement of sieve elements (SEs). In contrast, virions of Rice dwarf virus (RDV, genus Phytoreovirus) were observed in both phloem and mesophyll and the virus did not cause hyperplasia of SEs. The three phloem-limited reoviruses (but not RDV) all induced more flexible gateways at the SE-SE interfaces, especially the non-sieve plate interfaces. These flexible gateways were also observed for the first time at the cellular interfaces between SE and phloem parenchyma (PP). In plants infected with any of the reoviruses, virus-like particles could be seen within the flexible gateways, suggesting that these gateways may serve as channels for the movement of plant reoviruses with their large virions between SEs or between SEs and PP. SE hyperplasia and the increase in flexible gateways may be a universal strategy for the movement of phloem-limited reoviruses.

  12. Communicating Astronomy with the Public (Youth) as the Gateway to Development

    NASA Astrophysics Data System (ADS)

    Crabtree, Dennis R.

    2015-03-01

    Astronomy has a unique ability to excite and stimulate the curiosity of children. Because of this, society can use astronomy as a gateway to lead children on a path towards future learning of science and technology, and potentially to careers in these areas.

  13. Assessment and Placement: Supporting Student Success in College Gateway Courses

    ERIC Educational Resources Information Center

    Vandal, Bruce

    2014-01-01

    Evidence is mounting that the vast majority of students who are currently placed into prerequisite remedial education could be successful in gateway college-­level courses if they receive additional academic support as a corequisite. Recent research on college placement exams reveals that the exams are unreliable at predicting college success, and…

  14. The emergence of a global right to health norm – the unresolved case of universal access to quality emergency obstetric care

    PubMed Central

    2014-01-01

    Background The global response to HIV suggests the potential of an emergent global right to health norm, embracing shared global responsibility for health, to assist policy communities in framing the obligations of the domestic state and the international community. Our research explores the extent to which this global right to health norm has influenced the global policy process around maternal health rights, with a focus on universal access to emergency obstetric care. Methods In examining the extent to which arguments stemming from a global right to health norm have been successful in advancing international policy on universal access to emergency obstetric care, we looked at the period from 1985 to 2013 period. We adopted a qualitative case study approach applying a process-tracing methodology using multiple data sources, including an extensive literature review and limited key informant interviews to analyse the international policy agenda setting process surrounding maternal health rights, focusing on emergency obstetric care. We applied John Kingdon's public policy agenda setting streams model to analyse our data. Results Kingdon’s model suggests that to succeed as a mobilising norm, the right to health could work if it can help bring the problem, policy and political streams together, as it did with access to AIDS treatment. Our analysis suggests that despite a normative grounding in the right to health, prioritisation of the specific maternal health entitlements remains fragmented. Conclusions Despite United Nations recognition of maternal mortality as a human rights issue, the relevant policy communities have not yet managed to shift the policy agenda to prioritise the global right to health norm of shared responsibility for realising access to emergency obstetric care. The experience of HIV advocates in pushing for global solutions based on right to health principles, including participation, solidarity and accountability; suggest potential avenues for

  15. Wireless access to a pharmaceutical database: a demonstrator for data driven Wireless Application Protocol (WAP) applications in medical information processing.

    PubMed

    Schacht Hansen, M; Dørup, J

    2001-01-01

    The Wireless Application Protocol technology implemented in newer mobile phones has built-in facilities for handling much of the information processing needed in clinical work. To test a practical approach we ported a relational database of the Danish pharmaceutical catalogue to Wireless Application Protocol using open source freeware at all steps. We used Apache 1.3 web software on a Linux server. Data containing the Danish pharmaceutical catalogue were imported from an ASCII file into a MySQL 3.22.32 database using a Practical Extraction and Report Language script for easy update of the database. Data were distributed in 35 interrelated tables. Each pharmaceutical brand name was given its own card with links to general information about the drug, active substances, contraindications etc. Access was available through 1) browsing therapeutic groups and 2) searching for a brand name. The database interface was programmed in the server-side scripting language PHP3. A free, open source Wireless Application Protocol gateway to a pharmaceutical catalogue was established to allow dial-in access independent of commercial Wireless Application Protocol service providers. The application was tested on the Nokia 7110 and Ericsson R320s cellular phones. We have demonstrated that Wireless Application Protocol-based access to a dynamic clinical database can be established using open source freeware. The project opens perspectives for a further integration of Wireless Application Protocol phone functions in clinical information processing: Global System for Mobile communication telephony for bilateral communication, asynchronous unilateral communication via e-mail and Short Message Service, built-in calculator, calendar, personal organizer, phone number catalogue and Dictaphone function via answering machine technology. An independent Wireless Application Protocol gateway may be placed within hospital firewalls, which may be an advantage with respect to security. However, if

  16. Sierra Stars Observatory Network: An Accessible Global Network

    NASA Astrophysics Data System (ADS)

    Williams, Richard; Beshore, Edward

    2011-03-01

    The Sierra Stars Observatory Network (SSON) is a unique partnership among professional observatories that provides its users with affordable high-quality calibrated image data. SSON comprises observatories in the Northern and Southern Hemisphere and is in the process of expanding to a truly global network capable of covering the entire sky 24 hours a day in the near future. The goal of SSON is to serve the needs of science-based projects and programs. Colleges, universities, institutions, and individuals use SSON for their education and research projects. The mission of SSON is to promote and expand the use of its facilities among the thousands of colleges and schools worldwide that do not have access to professional-quality automated observatory systems to use for astronomy education and research. With appropriate leadership and guidance educators can use SSON to help teach astronomy and do meaningful scientific projects. The relatively small cost of using SSON for this type of work makes it affordable and accessible for educators to start using immediately. Remote observatory services like SSON need to evolve to better support education and research initiatives of colleges, institutions and individual investigators. To meet these needs, SSON is developing a sophisticated interactive scheduling system to integrate among the nodes of the observatory network. This will enable more dynamic observations, including immediate priority interrupts, acquiring moving objects using ephemeris data, and more.

  17. Adolescents and Young Adults' Perceptions of Electronic Cigarettes as a Gateway to Smoking: A Qualitative Study in Switzerland

    ERIC Educational Resources Information Center

    Akre, Christina; Suris, Joan-Carles

    2017-01-01

    Electronic cigarettes (ECs) acting as a gateway to smoking traditional cigarettes (TCs) is a growing public health concern of EC use among youths. To gather the opinions and perceptions of adolescents and young adults (AYAs) on whether and how EC can act as a gateway to smoking TC among youths. A qualitative method included 42 AYAs. Participants…

  18. Utilization of communities of practice for ongoing learning and knowledge dissemination: Making the case for the Global Alliance for Nursing and Midwifery (GANM).

    PubMed

    Gresh, Ashley; Mena-Carrasco, Fernando; Rauh, Allison; Pfaff, Teresa

    2017-09-01

    With the growing connectivity among countries and healthcare practitioners, nurses and midwives in low resource settings are connecting digitally to access information through online platforms. Ninety eight percent of adults online report visiting a social network in the past month, and spend almost two hours per day engaged with social media. In an increasingly interconnected world, innovative strategies are needed to translate knowledge into practice. The Global Alliance for Nursing and Midwifery (GANM), part of the Pan American Health Organization (PAHO)/World Health Organization (WHO) Collaborating Center (CC) at the Johns Hopkins University School of Nursing (JHSON) leverages its Knowledge Gateway to facilitate translating knowledge into practice in order to achieve the Sustainable Development Goals (SDGs). This paper explores the concepts of knowledge dissemination, communities of practice, and makes the case for further using the GANM as an exemplary model to build the capacity of nurses and midwives globally. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. A plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector

    PubMed Central

    2013-01-01

    Background Valuable clone collections encoding the complete ORFeomes for some model organisms have been constructed following the completion of their genome sequencing projects. These libraries are based on Gateway cloning technology, which facilitates the study of protein function by simplifying the subcloning of open reading frames (ORF) into any suitable destination vector. The expression of proteins of interest as fusions with functional modules is a frequent approach in their initial functional characterization. A limited number of Gateway destination expression vectors allow the construction of fusion proteins from ORFeome-derived sequences, but they are restricted to the possibilities offered by their inbuilt functional modules and their pre-defined model organism-specificity. Thus, the availability of cloning systems that overcome these limitations would be highly advantageous. Results We present a versatile cloning toolkit for constructing fully-customizable three-part fusion proteins based on the MultiSite Gateway cloning system. The fusion protein components are encoded in the three plasmids integral to the kit. These can recombine with any purposely-engineered destination vector that uses a heterologous promoter external to the Gateway cassette, leading to the in-frame cloning of an ORF of interest flanked by two functional modules. In contrast to previous systems, a third part becomes available for peptide-encoding as it no longer needs to contain a promoter, resulting in an increased number of possible fusion combinations. We have constructed the kit’s component plasmids and demonstrate its functionality by providing proof-of-principle data on the expression of prototype fluorescent fusions in transiently-transfected cells. Conclusions We have developed a toolkit for creating fusion proteins with customized N- and C-term modules from Gateway entry clones encoding ORFs of interest. Importantly, our method allows entry clones obtained from ORFeome

  20. A plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector.

    PubMed

    Buj, Raquel; Iglesias, Noa; Planas, Anna M; Santalucía, Tomàs

    2013-08-20

    Valuable clone collections encoding the complete ORFeomes for some model organisms have been constructed following the completion of their genome sequencing projects. These libraries are based on Gateway cloning technology, which facilitates the study of protein function by simplifying the subcloning of open reading frames (ORF) into any suitable destination vector. The expression of proteins of interest as fusions with functional modules is a frequent approach in their initial functional characterization. A limited number of Gateway destination expression vectors allow the construction of fusion proteins from ORFeome-derived sequences, but they are restricted to the possibilities offered by their inbuilt functional modules and their pre-defined model organism-specificity. Thus, the availability of cloning systems that overcome these limitations would be highly advantageous. We present a versatile cloning toolkit for constructing fully-customizable three-part fusion proteins based on the MultiSite Gateway cloning system. The fusion protein components are encoded in the three plasmids integral to the kit. These can recombine with any purposely-engineered destination vector that uses a heterologous promoter external to the Gateway cassette, leading to the in-frame cloning of an ORF of interest flanked by two functional modules. In contrast to previous systems, a third part becomes available for peptide-encoding as it no longer needs to contain a promoter, resulting in an increased number of possible fusion combinations. We have constructed the kit's component plasmids and demonstrate its functionality by providing proof-of-principle data on the expression of prototype fluorescent fusions in transiently-transfected cells. We have developed a toolkit for creating fusion proteins with customized N- and C-term modules from Gateway entry clones encoding ORFs of interest. Importantly, our method allows entry clones obtained from ORFeome collections to be used without prior

  1. Los Angeles - Gateway Freight Advanced Traveler Information System : demonstration team final report.

    DOT National Transportation Integrated Search

    2015-02-01

    This Demonstration Team Final Report has been prepared to provide an overview of the conduct and qualitative findings of the LA-Gateway FRATIS development and testing program. More specifically, this document provides: A description of the testin...

  2. "TIS": An Intelligent Gateway Computer for Information and Modeling Networks. Overview.

    ERIC Educational Resources Information Center

    Hampel, Viktor E.; And Others

    TIS (Technology Information System) is being used at the Lawrence Livermore National Laboratory (LLNL) to develop software for Intelligent Gateway Computers (IGC) suitable for the prototyping of advanced, integrated information networks. Dedicated to information management, TIS leads the user to available information resources, on TIS or…

  3. Prioritizing Active Learning: An Exploration of Gateway Courses in Political Science

    ERIC Educational Resources Information Center

    Archer, Candace C.; Miller, Melissa K.

    2011-01-01

    Prior research in political science and other disciplines demonstrates the pedagogical and practical benefits of active learning. Less is known, however, about the extent to which active learning is used in political science classrooms. This study assesses the prioritization of active learning in "gateway" political science courses, paying…

  4. Retinal Evaluation Using Optical Coherence Tomography (OCT) During Deep Space Gateway Missions

    NASA Astrophysics Data System (ADS)

    Stenger, M. B.; Laurie, S. S.; Macias, B. R.; Barr, Y. R.

    2018-02-01

    Optical Coherence Tomography (OCT) imaging will be conducted before, during, and after Deep Space Gateway missions to evaluate changes in the retina and, in particular, the optic nerve head and surrounding structures. Additional parameters will be collected before and after flight.

  5. Low-Latency Telerobotic Sample Return and Biomolecular Sequencing for Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Lupisella, M.; Bleacher, J.; Lewis, R.; Dworkin, J.; Wright, M.; Burton, A.; Rubins, K.; Wallace, S.; Stahl, S.; John, K.; Archer, D.; Niles, P.; Regberg, A.; Smith, D.; Race, M.; Chiu, C.; Russell, J.; Rampe, E.; Bywaters, K.

    2018-02-01

    Low-latency telerobotics, crew-assisted sample return, and biomolecular sequencing can be used to acquire and analyze lunar farside and/or Apollo landing site samples. Sequencing can also be used to monitor and study Deep Space Gateway environment and crew health.

  6. It's about the Gateway Courses: Defining and Contextualizing the Issue

    ERIC Educational Resources Information Center

    Koch, Andrew K.

    2017-01-01

    This introductory chapter defines the phrase gateway courses, describes why these courses are one of the most compelling issues in the contemporary student success movement, and details what is at stake if the issues associated with these courses are left unaddressed.

  7. Access to cancer screening for women with mobility disabilities.

    PubMed

    Angus, Jan; Seto, Lisa; Barry, Nancy; Cechetto, Naomi; Chandani, Samira; Devaney, Julie; Fernando, Sharmini; Muraca, Linda; Odette, Fran

    2012-03-01

    Women with mobility disabilities are less likely to access cancer screening, even when they have a primary care provider. The Gateways to Cancer Screening project was initiated to document the challenges for women with disabilities in their access and experiences of screening for breast, cervical and colorectal cancer. The study followed the tenets of participatory action research. Five peer-led focus groups were held with 24 women with mobility disabilities. Study participants identified multiple and interacting institutional barriers to cancer screening. Their discussions highlighted the complex work of (1) arranging and attending health-related appointments, (2) confronting normative assumptions about women's bodies and (3) securing reliable health care and information. These overlapping, mutually reinforcing issues interact to shape how women with disabilities access and experience cancer screening. We explore implications for redesign of cancer screening services and education of health providers, providing specific recommendations suggested by our participants and the findings.

  8. Preserved semantic access in global amnesia and hippocampal damage.

    PubMed

    Giovagnoli, A R; Erbetta, A; Bugiani, O

    2001-12-01

    C.B., a right-handed 33-year-old man, presented with anterograde amnesia after acute heart block. Cognitive abilities were normal except for serious impairment of long-term episodic memory. The access to semantic information was fully preserved. Magnetic resonance showed high signal intensity and marked volume loss in the hippocampus bilaterally; the left and right parahippocampal gyrus, lateral occipito-temporal gyrus, inferior temporal gyrus, and lateral temporal cortex were normal. This case underlines that global amnesia associated with hippocampal damage does not affect semantic memory. Although the hippocampus is important in retrieving context-linked information, its role is not so crucial in retrieving semantic contents. Cortical areas surrounding the hippocampus and lateral temporal areas might guide the recall of semantic information.

  9. GATEWAY Demonstrations: LED System Performance in a Trial Installation--Two Years Later, Yuma Border Patrol, Yuma, Arizona

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilkerson, Andrea M.; Sullivan, Gregory P.; Davis, Robert G.

    Along the Yuma Sector Border Patrol Area in Yuma, Arizona, the GATEWAY program conducted a trial demonstration in which the incumbent quartz metal halide area lighting was replaced with LED at three pole locations at the Yuma Sector Border Patrol Area in Yuma, Arizona. The retrofit was documented to better understand LED technology performance in high-temperature environments. This report follows the GATEWAY Yuma Phase 1.1 Report and reflects LED system results documented two years after the demonstration began.

  10. GATEWAY Demonstrations: LED System Performance in a Trial Installation--One Year Later, Yuma Border Patrol, Yuma, Arizona

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilkerson, A. M.; Davis, R. G.

    Along the Yuma Sector Border Patrol Area in Yuma, Arizona, the GATEWAY program conducted a trial demonstration in which the incumbent quartz metal halide area lighting was replaced with LED at three pole locations at the Yuma Sector Border Patrol Area in Yuma, Arizona. The retrofit was documented to better understand LED technology performance in high-temperature environments. This report follows the GATEWAY Yuma Phase 1.0 Report and reflects LED system results documented one year after the demonstration began.

  11. Gateways and Water Mass Mixing in the Late Cretaceous North Atlantic

    NASA Astrophysics Data System (ADS)

    Asgharian Rostami, M.; Martin, E. E.; MacLeod, K. G.; Poulsen, C. J.; Vande Guchte, A.; Haynes, S.

    2017-12-01

    Regions of intermediate/deep water formation and water-mass mixing in the North Atlantic are poorly defined for the Late Cretaceous, a time of gateway evolution and cooler conditions following the Mid Cretaceous greenhouse. Improved proxy data combined with modeling efforts are required to effectively evaluate the relationship between CO2, paleogeography, and circulation during this cooler interval. We analyzed and compiled latest Cretaceous (79 - 66 Ma) ɛNd and δ13C records from seven bathyal (paleodepths 0.2 - 2 km) and eight abyssal (paleodepths > 2 km) sites in the North Atlantic. Data suggest local downwelling of Northern Component Water (NCW; ɛNd -9.5 and δ13C 1.7 ‰) is the primary source of intermediate/deep water masses in the basin. As this water flows southward and ages, δ13C values decrease and ɛNd values increase; however, additional chemical changes at several sites require mixing with contributions from several additional water masses. Lower ɛNd ( -10) and higher δ13C ( 1.9 ‰) values in the deep NW part of the basin indicate proximal contributions from a region draining old continental crust, potentially representing deep convection following opening of the Labrador Sea. In the deep NE Iberian Basin, higher ɛNd ( -7) and lower δ13C ( 0.8 ‰) during the Campanian suggest mixing with a Tethyan source (ɛNd -7 and δ13C 0.1 ‰) whose importance decreased with restriction of that gateway in the Maastrichtian. Data from bathyal sites suggest additional mixing. In the SE Cape Verde region, observed ɛNd variations from -10 in the Campanian to -13 and -12 in the early and late Maastrichtian, respectively, may record variations in output rates of Tethyan and/or NCW sources and Demerara Bottom Water (ɛNd -16), a proposed warm saline intermediate water mass formed in shallow, equatorial seas. Pacific inflow through the Caribbean gateway impacts intermediate sites at Blake Nose (ɛNd values -8), particularly the shallowest site during the late

  12. The Importance of Conducting Life Sciences Experiments on the Deep Space Gateway Platform

    NASA Astrophysics Data System (ADS)

    Bhattacharya, S.

    2018-02-01

    Life science research on the Deep Space Gateway platform is an important precursor for long term human exploration of deep space. Ideas for utilizing flight hardware and well characterized model organisms will be discussed.

  13. “Puerto Rico: gateway to landscape” from an ecological perspective

    Treesearch

    Grizelle Gonzalez

    2015-01-01

    The exhibit Puerto Rico: Gateway to Landscape proposes to explore various ways in which citizens approach the landscape, or construct it – inside and outside the city – and considers city planning, the creation of parks and natural reserves, and their interpretation. From a perspective of citizen involvement, this thematic scaffolding related to landscape and the...

  14. Tobacco, the Common Enemy and a Gateway Drug: Policy Implications

    ERIC Educational Resources Information Center

    Torabi, Mohammad R.; Jun, Mi Kyung; Nowicke, Carole; Seitz de Martinez, Barbara; Gassman, Ruth

    2010-01-01

    For the four leading causes of death in the United States (heart disease, cancer, stroke and chronic respiratory disease), tobacco use is a common risk factor. Tobacco use is responsible for almost 450,000 deaths per year and impacts the health of every member of our society. Tobacco is a gateway drug for substance abuse. That role is critical to…

  15. Construction of two Lactococcus lactis expression vectors combining the Gateway and the NIsin Controlled Expression systems.

    PubMed

    Douillard, François P; Mahony, Jennifer; Campanacci, Valérie; Cambillau, Christian; van Sinderen, Douwe

    2011-09-01

    Over the last 10 years, the NIsin Controlled Expression (NICE) system has been extensively used in the food-grade bacterium Lactococcus lactis subsp. cremoris to produce homologous and heterologous proteins for academic and biotechnological purposes. Although various L. lactis molecular tools have been developed, no expression vectors harboring the popular Gateway recombination system are currently available for this widely used cloning host. In this study, we constructed two expression vectors that combine the NICE and the Gateway recombination systems and we tested their applicability by recombining and over-expressing genes encoding structural proteins of lactococcal phages Tuc2009 and TP901-1. Over-expressed phage proteins were analyzed by immunoblotting and purified by His-tag affinity chromatography with protein productions yielding 2.8-3.7 mg/l of culture. This therefore is the first description of L. lactis NICE expression vectors which integrate the Gateway cloning technology and which are suitable for the production of sufficient amounts of proteins to facilitate subsequent structural and functional analyses. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. The scientific consensus on climate change as a gateway belief: experimental evidence.

    PubMed

    van der Linden, Sander L; Leiserowitz, Anthony A; Feinberg, Geoffrey D; Maibach, Edward W

    2015-01-01

    There is currently widespread public misunderstanding about the degree of scientific consensus on human-caused climate change, both in the US as well as internationally. Moreover, previous research has identified important associations between public perceptions of the scientific consensus, belief in climate change and support for climate policy. This paper extends this line of research by advancing and providing experimental evidence for a "gateway belief model" (GBM). Using national data (N = 1104) from a consensus-message experiment, we find that increasing public perceptions of the scientific consensus is significantly and causally associated with an increase in the belief that climate change is happening, human-caused and a worrisome threat. In turn, changes in these key beliefs are predictive of increased support for public action. In short, we find that perceived scientific agreement is an important gateway belief, ultimately influencing public responses to climate change.

  17. The Scientific Consensus on Climate Change as a Gateway Belief: Experimental Evidence

    PubMed Central

    van der Linden, Sander L.; Leiserowitz, Anthony A.; Feinberg, Geoffrey D.; Maibach, Edward W.

    2015-01-01

    There is currently widespread public misunderstanding about the degree of scientific consensus on human-caused climate change, both in the US as well as internationally. Moreover, previous research has identified important associations between public perceptions of the scientific consensus, belief in climate change and support for climate policy. This paper extends this line of research by advancing and providing experimental evidence for a “gateway belief model” (GBM). Using national data (N = 1104) from a consensus-message experiment, we find that increasing public perceptions of the scientific consensus is significantly and causally associated with an increase in the belief that climate change is happening, human-caused and a worrisome threat. In turn, changes in these key beliefs are predictive of increased support for public action. In short, we find that perceived scientific agreement is an important gateway belief, ultimately influencing public responses to climate change. PMID:25714347

  18. Data Integration Support for Data Served in the OPeNDAP and OGC Environments

    NASA Technical Reports Server (NTRS)

    McDonald, Kenneth R.; Wharton, Stephen W. (Technical Monitor)

    2006-01-01

    NASA is coordinating a technology development project to construct a gateway between system components built upon the Open-source Project for a Network Data AcceSs Protocol (OPeNDAP) and those made available made available via interfaces specified by the Open Geospatial Consortium (OGC). This project is funded though the Advanced Collaborative Connections for Earth-Sun System Science (ACCESS) Program and is a NASA contribution to the Committee on Earth Satellites (CEOS) Working Group on Information Systems and Services (WGISS). The motivation for the project is the set of data integration needs that have been expressed by the Coordinated Enhanced Observing Period (CEOP), an international program that is addressing the study of the global water cycle. CEOP is assembling a large collection in situ and satellite data and mode1 results from a wide variety of sources covering 35 sites around the globe. The data are provided by systems based on either the OPeNDAP or OGC protocols but the research community desires access to the full range of data and associated services from a single client. This presentation will discuss the current status of the OPeNDAP/OGC Gateway Project. The project is building upon an early prototype that illustrated the feasibility of such a gateway and which was demonstrated to the CEOP science community. In its first year as an ACCESS project, the effort has been has focused on the design of the catalog and data services that will be provided by the gateway and the mappings between the metadata and services provided in the two environments.

  19. A Technology-Enriched Active Learning Space for a New Gateway Education Programme in Hong Kong: A Platform for Nurturing Student Innovations

    ERIC Educational Resources Information Center

    Chiu, Pit Ho Patrio

    2016-01-01

    A Gateway Education Programme is established in Hong Kong that aims to broaden students' interdisciplinary knowledge and nurture student innovations under the Discovery-enriched Curriculum. To support the initiative, a novel idea was proposed for the creation of a Gateway Education Laboratory (GE Lab) with a highly configurable layout equipped…

  20. The emergence of global health partnerships as facilitators of access to medication in Africa: a narrative policy analysis.

    PubMed

    Ngoasong, Michael Zisuh

    2009-03-01

    Over the last decade global health partnerships (GHPs) have been formed to provide a better policy response to Africa's health problems. This paper uses narrative policy analysis to explain the historical processes and challenges facing national and global health policy in facilitating access to medication in African countries. An overview of the historical context of events leading to the creation of GHPs is followed by a content and context analysis of two GHPs - Roll Back Malaria partnership and the Accelerating Access Initiative. The historical narratives implicitly reflect the context in which policy decisions are produced and implemented. The deployment of GHPs in Africa reflects a convergence of the competing and conflicting narratives, in relating to strategies previously promoted by various multilateral and bilateral development agencies, international civil society organizations, and the private commercial industry to facilitate access to medication.

  1. The Case for Intentionally Interwoven Peer Learning Supports in Gateway-Course Improvement Efforts

    ERIC Educational Resources Information Center

    Dvorak, Johanna; Tucker, Kathryn

    2017-01-01

    This chapter describes how peer learning support programs can be used to improve learning and success in gateway courses. It provides examples from two institutions to further illustrate how this promising approach can improve student outcomes.

  2. Bibliographic Post-Processing with the TIS Intelligent Gateway: Analytical and Communication Capabilities.

    ERIC Educational Resources Information Center

    Burton, Hilary D.

    TIS (Technology Information System) is an intelligent gateway system capable of performing quantitative evaluation and analysis of bibliographic citations using a set of Process functions. Originally developed by Lawrence Livermore National Laboratory (LLNL) to analyze information retrieved from three major federal databases, DOE/RECON,…

  3. Evaluation of the Gateway Monument Demonstration Program: Safety, Economic and Social Impact Analysis

    DOT National Transportation Integrated Search

    2009-09-01

    The Gateway Monument Demonstration Program (GMDP) facilitated the construction of freestanding structures or signage along roadways to communicate the name of a city, county or township to motorists. The GMDP spanned a four-year period, commencing on...

  4. IoT gateways, cloud and the last mile for energy efficiency and sustainability in the era of CPS expansion: "A bot is irrigating my farm.. "

    NASA Astrophysics Data System (ADS)

    Papageorgas, Panagiotis G.; Agavanakis, Kyriakos; Dogas, Ioannis; Piromalis, Dimitrios D.

    2018-05-01

    A cloud-based architecture is presented for the internetworking of sensors and actuators through a universal gateway, network server and application user interface design. The proposed approach targets to Energy Efficiency and sustainability in a holistic way, by integrating an open-source test bed prototype based on long-range low-bandwidth wireless networking technology for sensing and actuation as the elementary block of a viable, cost-effective and reliable solution. The prototype presented is capable of supporting both sensors and actuators, processing data locally and transmitting the results of the imposed computations to a higher level node. Additionally, it is combined with a service-oriented architecture and involves publish/subscribe middleware protocols and cloud technology to confront with the system needs in terms of data volume and processing power. In this context, the integration of instant message (chat) services is demonstrated so that they can be part of an emerging global-scope eco-system of Cyber-Physical Systems to support a wide variety of IoT applications, with strong advantages such as usability, scalability and security, while adopting a unified gateway design and a simple - yet powerful - user interface.

  5. Inequities in access to HIV prevention services for transgender men: results of a global survey of men who have sex with men.

    PubMed

    Scheim, Ayden I; Santos, Glenn-Milo; Arreola, Sonya; Makofane, Keletso; Do, Tri D; Hebert, Patrick; Thomann, Matthew; Ayala, George

    2016-01-01

    Free or low-cost HIV testing, condoms, and lubricants are foundational HIV prevention strategies, yet are often inaccessible for men who have sex with men (MSM). In the global context of stigma and poor healthcare access, transgender (trans) MSM may face additional barriers to HIV prevention services. Drawing on data from a global survey of MSM, we aimed to describe perceived access to prevention services among trans MSM, examine associations between stigma and access, and compare access between trans MSM and cisgender (non-transgender) MSM. The 2014 Global Men's Health and Rights online survey was open to MSM (inclusive of trans MSM) from any country and available in seven languages. Baseline data (n=3857) were collected from July to October 2014. Among trans MSM, correlations were calculated between perceived service accessibility and anti-transgender violence, healthcare provider stigma, and discrimination. Using a nested matched-pair study design, trans MSM were matched 4:1 to cisgender MSM on age group, region, and HIV status, and conditional logistic regression models compared perceived access to prevention services by transgender status. About 3.4% of respondents were trans men, of whom 69 were included in the present analysis. The average trans MSM participant was 26 to 35 years old (56.5%); lived in western Europe, North America, or Oceania (75.4%); and reported being HIV-negative (98.6%). HIV testing, condoms, and lubricants were accessible for 43.5, 53.6, and 26.1% of trans MSM, respectively. Ever having been arrested or convicted due to being trans and higher exposure to healthcare provider stigma in the past six months were associated with less access to some prevention services. Compared to matched cisgender controls, trans MSM reported significantly lower odds of perceived access to HIV testing (OR=0.57, 95% CI=0.33, 0.98) and condom-compatible lubricants (OR=0.54, 95% CI=0.30, 0.98). This first look at access to HIV prevention services for trans MSM

  6. WRF4SG: A Scientific Gateway for climate experiment workflows

    NASA Astrophysics Data System (ADS)

    Blanco, Carlos; Cofino, Antonio S.; Fernandez-Quiruelas, Valvanuz

    2013-04-01

    The Weather Research and Forecasting model (WRF) is a community-driven and public domain model widely used by the weather and climate communities. As opposite to other application-oriented models, WRF provides a flexible and computationally-efficient framework which allows solving a variety of problems for different time-scales, from weather forecast to climate change projection. Furthermore, WRF is also widely used as a research tool in modeling physics, dynamics, and data assimilation by the research community. Climate experiment workflows based on Weather Research and Forecasting (WRF) are nowadays among the one of the most cutting-edge applications. These workflows are complex due to both large storage and the huge number of simulations executed. In order to manage that, we have developed a scientific gateway (SG) called WRF for Scientific Gateway (WRF4SG) based on WS-PGRADE/gUSE and WRF4G frameworks to ease achieve WRF users needs (see [1] and [2]). WRF4SG provides services for different use cases that describe the different interactions between WRF users and the WRF4SG interface in order to show how to run a climate experiment. As WS-PGRADE/gUSE uses portlets (see [1]) to interact with users, its portlets will support these use cases. A typical experiment to be carried on by a WRF user will consist on a high-resolution regional re-forecast. These re-forecasts are common experiments used as input data form wind power energy and natural hazards (wind and precipitation fields). In the cases below, the user is able to access to different resources such as Grid due to the fact that WRF needs a huge amount of computing resources in order to generate useful simulations: * Resource configuration and user authentication: The first step is to authenticate on users' Grid resources by virtual organizations. After login, the user is able to select which virtual organization is going to be used by the experiment. * Data assimilation: In order to assimilate the data sources

  7. Deep Space Gateway - Enabling Missions to Mars

    NASA Technical Reports Server (NTRS)

    Rucker, Michelle; Connolly, John

    2017-01-01

    There are many opportunities for commonality between Lunar vicinity and Mars mission hardware and operations. Best approach: Identify Mars mission risks that can be bought down with testing in the Lunar vicinity, then explore hardware and operational concepts that work for both missions with minimal compromise. Deep Space Transport will validate the systems and capabilities required to send humans to Mars orbit and return to Earth. Deep Space Gateway provides a convenient assembly, checkout, and refurbishment location to enable Mars missions Current deep space transport concept is to fly missions of increasing complexity: Shakedown cruise, Mars orbital mission, Mars surface mission; Mars surface mission would require additional elements.

  8. Efficacy of a Summer Intervention to Improve GATEWAY Mathematics Examination Scores

    ERIC Educational Resources Information Center

    Jackson, Arthur Wesley

    2011-01-01

    Less than 50% of students from an inner-city high school in a southeastern US state who took the GATEWAY mathematics exam (2001-2007) earned a passing score on the first attempt, prompting teachers at the school to begin a summer intervention program based on Bandura's Self Efficacy Theory, to help them succeed on a subsequent reexamination. The…

  9. Characterization of Outer Space Radiation Induced Changes in Extremophiles Utilizing Deep Space Gateway Opportunities

    NASA Astrophysics Data System (ADS)

    Venkateswaran, K.; Wang, C.; Smith, D.; Mason, C.; Landry, K.; Rettberg, P.

    2018-02-01

    Extremophilic microbial survival, adaptation, biological functions, and molecular mechanisms associated with outer space radiation can be tested by exposing them onto Deep Space Gateway hardware (inside/outside) using microbiology and molecular biology techniques.

  10. America's freight transportation gateways : connecting our nation to places and markets abroad : [2009

    DOT National Transportation Integrated Search

    2009-11-01

    This report ranks freight gateways by the value of merchandise trade they handle. Value : data were compiled from multiple sources, allowing comparison of all the freight modes. : See box 2 for a detailed description of the freight data sources. : Th...

  11. Enabling Data Intensive Science through Service Oriented Science: Virtual Laboratories and Science Gateways

    NASA Astrophysics Data System (ADS)

    Lescinsky, D. T.; Wyborn, L. A.; Evans, B. J. K.; Allen, C.; Fraser, R.; Rankine, T.

    2014-12-01

    We present collaborative work on a generic, modular infrastructure for virtual laboratories (VLs, similar to science gateways) that combine online access to data, scientific code, and computing resources as services that support multiple data intensive scientific computing needs across a wide range of science disciplines. We are leveraging access to 10+ PB of earth science data on Lustre filesystems at Australia's National Computational Infrastructure (NCI) Research Data Storage Infrastructure (RDSI) node, co-located with NCI's 1.2 PFlop Raijin supercomputer and a 3000 CPU core research cloud. The development, maintenance and sustainability of VLs is best accomplished through modularisation and standardisation of interfaces between components. Our approach has been to break up tightly-coupled, specialised application packages into modules, with identified best techniques and algorithms repackaged either as data services or scientific tools that are accessible across domains. The data services can be used to manipulate, visualise and transform multiple data types whilst the scientific tools can be used in concert with multiple scientific codes. We are currently designing a scalable generic infrastructure that will handle scientific code as modularised services and thereby enable the rapid/easy deployment of new codes or versions of codes. The goal is to build open source libraries/collections of scientific tools, scripts and modelling codes that can be combined in specially designed deployments. Additional services in development include: provenance, publication of results, monitoring, workflow tools, etc. The generic VL infrastructure will be hosted at NCI, but can access alternative computing infrastructures (i.e., public/private cloud, HPC).The Virtual Geophysics Laboratory (VGL) was developed as a pilot project to demonstrate the underlying technology. This base is now being redesigned and generalised to develop a Virtual Hazards Impact and Risk Laboratory

  12. SU-D-BRD-03: A Gateway for GPU Computing in Cancer Radiotherapy Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jia, X; Folkerts, M; Shi, F

    Purpose: Graphics Processing Unit (GPU) has become increasingly important in radiotherapy. However, it is still difficult for general clinical researchers to access GPU codes developed by other researchers, and for developers to objectively benchmark their codes. Moreover, it is quite often to see repeated efforts spent on developing low-quality GPU codes. The goal of this project is to establish an infrastructure for testing GPU codes, cross comparing them, and facilitating code distributions in radiotherapy community. Methods: We developed a system called Gateway for GPU Computing in Cancer Radiotherapy Research (GCR2). A number of GPU codes developed by our group andmore » other developers can be accessed via a web interface. To use the services, researchers first upload their test data or use the standard data provided by our system. Then they can select the GPU device on which the code will be executed. Our system offers all mainstream GPU hardware for code benchmarking purpose. After the code running is complete, the system automatically summarizes and displays the computing results. We also released a SDK to allow the developers to build their own algorithm implementation and submit their binary codes to the system. The submitted code is then systematically benchmarked using a variety of GPU hardware and representative data provided by our system. The developers can also compare their codes with others and generate benchmarking reports. Results: It is found that the developed system is fully functioning. Through a user-friendly web interface, researchers are able to test various GPU codes. Developers also benefit from this platform by comprehensively benchmarking their codes on various GPU platforms and representative clinical data sets. Conclusion: We have developed an open platform allowing the clinical researchers and developers to access the GPUs and GPU codes. This development will facilitate the utilization of GPU in radiation therapy field.« less

  13. Sensitivity of climate and Atlantic overturning circulation to uncertain ocean gateway configurations for the late Miocene

    NASA Astrophysics Data System (ADS)

    Bradshaw, C.; Lunt, D. J.; Flecker, R.; Martinez-Mendez, G.

    2013-12-01

    The palaeorecord documents late Miocene (11.6-5.3 Ma) climate to be much warmer and wetter than today yet CO2 reconstructions are similar to modern levels. Given the apparent decoupling between CO2 and warmth for this period we investigate here the role of the oceans. The late Miocene experienced significant tectonic change including the restriction of some of the last ocean gateways to close (Panama Gateway and Indonesian Seaway) and open (Bering Strait and Barents/Kara Sea). However, the timing and configuration of these tectonic changes is uncertain. The final closure of the Panama Gateway is dated to the Pliocene, but continental mammal exchange suggests the existence of a Central American archipelago from the mid-late Miocene. The Bering Strait is typically assumed to have opened at the very end of the late Miocene/early Pliocene based on diatom exchange, but other marine and terrestrial evidence points to a much earlier, perhaps intermittent, opening. The timing of the restriction of the Indonesian Seaway is very poorly constrained at middle Miocene to Pliocene. The Barents Sea and Kara Sea shelves are documented as having being subject to extensive glacial erosion and post-glacial uplift since the Pliocene and throughout the Quaternary but records of uplift and erosion during the earlier Cenozoic are limited. However, the presence of significant preglacial sediments suggests that this region underwent tectonic uplift, volcanism and subsequent erosion during the Eocene-Miocene period although the age assignment of the data remains controversial. The Panama Gateway has been suggested to influence North Atlantic Deep Water (NADW) production through numerous modelling studies, the Bering Strait has been suggested to greatly impact NADW during the Quaternary, and the strength of Indonesian Throughflow is hypothesised to influence Agulhas Leakage, which, in turn, has been speculated to influence Atlantic meridional overturning and thus NADW production. Here, we

  14. Smokeless tobacco: a gateway to smoking or a way away from smoking.

    PubMed

    Melikian, Assieh A; Hoffmann, Dietrich

    2009-07-01

    Recently, tobacco companies have been marketing moist smokeless tobacco products that are 'spitless'. These products have lower concentrations of tobacco-specific nitrosamines and of other harmful chemicals than other tobacco products, but can deliver relatively high doses of nicotine. They are packaged in small sachets, similar to tea bags that are placed between cheek and gum. Global promotion of smokeless tobacco products is hotly debated among tobacco control and public health experts. Proponents point to the Swedish experience where snus (Swedish moist snuff) is widely used as an alternative to cigarette smoking among men. Meanwhile, Sweden has low rates of smoking and a lower rate of respiratory diseases and lung cancers by comparison to other developed countries. The opponents argue that snus has its own risks, that no form of tobacco should ever be promoted; and that 'snus is culture-bound and not transferable to other settings'. Critics also suspect that the tobacco industry will use snus marketing as a 'gateway' to promote cigarettes among young people. Research on the effects of marketing snus to smokers is too limited to support using snus as a harm-reduction tool, and the epidemiological data are not conclusive.

  15. A gateway for phylogenetic analysis powered by grid computing featuring GARLI 2.0.

    PubMed

    Bazinet, Adam L; Zwickl, Derrick J; Cummings, Michael P

    2014-09-01

    We introduce molecularevolution.org, a publicly available gateway for high-throughput, maximum-likelihood phylogenetic analysis powered by grid computing. The gateway features a garli 2.0 web service that enables a user to quickly and easily submit thousands of maximum likelihood tree searches or bootstrap searches that are executed in parallel on distributed computing resources. The garli web service allows one to easily specify partitioned substitution models using a graphical interface, and it performs sophisticated post-processing of phylogenetic results. Although the garli web service has been used by the research community for over three years, here we formally announce the availability of the service, describe its capabilities, highlight new features and recent improvements, and provide details about how the grid system efficiently delivers high-quality phylogenetic results. © The Author(s) 2014. Published by Oxford University Press, on behalf of the Society of Systematic Biologists.

  16. Enhancement of Mutual Discovery, Search, and Access of Data for Users of NASA and GEOSS-Cataloged Data Systems

    NASA Astrophysics Data System (ADS)

    Teng, W. L.; Maidment, D. R.; Rodell, M.; Strub, R. F.; Arctur, D. K.; Ames, D. P.; Vollmer, B.; Seiler, E.

    2014-12-01

    An ongoing NASA-funded project has removed a longstanding barrier to accessing NASA data (i.e., accessing archived time-step array data as point-time series) for selected variables of the North American and Global Land Data Assimilation Systems (NLDAS and GLDAS, respectively) and other EOSDIS (Earth Observing System Data Information System) data sets. These time series ("data rods") are pre-generated or generated on-the-fly (OTF), leveraging the NASA Simple Subset Wizard (SSW), a gateway to NASA data centers. Data rods Web services are accessible through the CUAHSI Hydrologic Information System (HIS) and the Goddard Earth Sciences Data and Information Services Center (GES DISC) but are not easily discoverable by users of other non-NASA data systems. The Global Earth Observation System of Systems (GEOSS) is a logical mechanism for providing access to the data rods, both pre-generated and OTF. There is an ongoing series of multi-organizational GEOSS Architecture Implementation Pilots, now in Phase-7 (AIP-7) and with a strong water sub-theme, that is aimed at the GEOSS Water Strategic Target "to produce [by 2015] comprehensive sets of data and information products to support decision-making for efficient management of the world's water resources, based on coordinated, sustained observations of the water cycle on multiple scales." The aim of this "GEOSS Water Services" project is to develop a distributed, global registry of water data, map, and modeling services catalogued using the standards and procedures of the Open Geospatial Consortium and the World Meteorological Organization. This project has already demonstrated that the GEOSS infrastructure can be leveraged to help provide access to time series of model grid information (e.g., NLDAS, GLDAS) or grids of information over a geographical domain for a particular time interval. A new NASA-funded project was begun, to expand on these early efforts to enhance the discovery, search, and access of NASA data by non

  17. Flooding and subsidence in the Thames Gateway: impact on insurance loss potential

    NASA Astrophysics Data System (ADS)

    Royse, Katherine; Horn, Diane; Eldridge, Jillian; Barker, Karen

    2010-05-01

    In the UK, household buildings insurance generally covers loss and damage to the insured property from a range of natural and human perils, including windstorm, flood, subsidence, theft, accidental fire and winter freeze. Consequently, insurers require a reasoned view on the likely scale of losses that they may face to assist in strategic planning, reinsurance structuring, regulatory returns and general risk management. The UK summer 2007 flood events not only provided a clear indication of the scale of potential losses that the industry could face from an individual event, with £3 billion in claims, but also identified a need for insurers and reinsurers to better understand how events may correlate in time and space, and how to most effectively use the computational models of extreme events that are commonly applied to reflect these correlations. In addition to the potential for temporal clustering of events such as windstorms and floods, there is a possibility that seemingly uncorrelated natural perils, such as floods and subsidence, may impact an insurer's portfolio. Where aggregations of large numbers of new properties are planned, such as in the Thames Gateway, consideration of the potential future risk of aggregate losses due to the combination of perils such as subsidence and flood is increasingly important within the insurance company's strategic risk management process. Whilst perils such as subsidence and flooding are generally considered independent within risk modelling, the potential for one event to influence the magnitude and likelihood of the other should be taken into account when determining risk level. In addition, the impact of correlated, but distinctive, loss causing events on particular property types may be significant, particularly if a specific property is designed to protect against one peril but is potentially susceptible to another. We suggest that flood events can lead to increased subsidence risk due to the weight of additional water

  18. GateWay Community College Water Resources Program Partnerships: An Opportunity for Program Success and Collaboration

    NASA Astrophysics Data System (ADS)

    Castaneda, M.

    2012-12-01

    GateWay Community College Water Resources Technologies (WRT) Program offers Certificate of Completions and Associate Degrees on Hydrologic Studies, Water Treatment and Wastewater Treatment. The program has been in existence since 1998 and has gone through several updates to meet the demand for professionals in those areas. The program includes theoretical and practical hands-on training in the monitoring of water quality and quantity as well as in water and industrial wastewater treatment. The WRT program offers online, face-to-face, and hybrid courses to address different student's needs for training. The program only Full-time faculty is supported by 15 adjunct- faculty professionals. Adjunct faculty is usually hired from a wide variety of professional people already working in the industry that have shown interest on teaching. Adjunct faculty also provide free tutoring to the WRT students when they are not teaching courses. The college Learning Center provides funding to support these tutoring activities. The program has an active Advisory Committee that provides guidance and recommends program changes to meet their training needs. This Advisory Committee is made of professionals from different federal, state, county agencies, and municipalities, private industry and consulting companies in the area. The Advisory Committee meets every year to provide feedback to GateWay on curriculum changes and commit to potential internship opportunities for the WRT students. Those internships (or voluntary work) are paid directly by the municipalities or agencies or can be paid by the GateWay WRT program. These internship jobs provides with an opportunity to actively promote the WRT program throughout the valley. The GateWay WRT program considers the Advisory Committee an essential component for the program success: the committee supports the program in recommending and acquiring the latest field equipment needed for the hands-on training. One of the main WRT program

  19. GATEWAY Report Brief: Tunable-White Lighting at the ACC Care Center

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    Summary of a GATEWAY program report that documented the performance of tunable-white LED lighting systems installed in several spaces within the ACC Care Center, a senior-care facility in Sacramento, CA. The project results included energy savings and improved lighting quality, as well as other possible health-related benefits that may have been attributable, at least in part, to the lighting changes.

  20. Developing Information Services and Tools to Access and Evaluate Data Quality in Global Satellite-based Precipitation Products

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Shie, C. L.; Meyer, D. J.

    2017-12-01

    Global satellite-based precipitation products have been widely used in research and applications around the world. Compared to ground-based observations, satellite-based measurements provide precipitation data on a global scale, especially in remote continents and over oceans. Over the years, satellite-based precipitation products have evolved from single sensor and single algorithm to multi-sensors and multi-algorithms. As a result, many satellite-based precipitation products have been enhanced such as spatial and temporal coverages. With inclusion of ground-based measurements, biases of satellite-based precipitation products have been significantly reduced. However, data quality issues still exist and can be caused by many factors such as observations, satellite platform anomaly, algorithms, production, calibration, validation, data services, etc. The NASA Goddard Earth Sciences (GES) Data and Information Services Center (DISC) is home to NASA global precipitation product archives including the Tropical Rainfall Measuring Mission (TRMM), the Global Precipitation Measurement (GPM), as well as other global and regional precipitation products. Precipitation is one of the top downloaded and accessed parameters in the GES DISC data archive. Meanwhile, users want to easily locate and obtain data quality information at regional and global scales to better understand how precipitation products perform and how reliable they are. As data service providers, it is necessary to provide an easy access to data quality information, however, such information normally is not available, and when it is available, it is not in one place and difficult to locate. In this presentation, we will present challenges and activities at the GES DISC to address precipitation data quality issues.

  1. Healthcare Data Gateways: Found Healthcare Intelligence on Blockchain with Novel Privacy Risk Control.

    PubMed

    Yue, Xiao; Wang, Huiju; Jin, Dawei; Li, Mingqiang; Jiang, Wei

    2016-10-01

    Healthcare data are a valuable source of healthcare intelligence. Sharing of healthcare data is one essential step to make healthcare system smarter and improve the quality of healthcare service. Healthcare data, one personal asset of patient, should be owned and controlled by patient, instead of being scattered in different healthcare systems, which prevents data sharing and puts patient privacy at risks. Blockchain is demonstrated in the financial field that trusted, auditable computing is possible using a decentralized network of peers accompanied by a public ledger. In this paper, we proposed an App (called Healthcare Data Gateway (HGD)) architecture based on blockchain to enable patient to own, control and share their own data easily and securely without violating privacy, which provides a new potential way to improve the intelligence of healthcare systems while keeping patient data private. Our proposed purpose-centric access model ensures patient own and control their healthcare data; simple unified Indicator-Centric Schema (ICS) makes it possible to organize all kinds of personal healthcare data practically and easily. We also point out that MPC (Secure Multi-Party Computing) is one promising solution to enable untrusted third-party to conduct computation over patient data without violating privacy.

  2. Gateways to Understanding: A Model for Exploring and Discerning Meaning from Experience

    ERIC Educational Resources Information Center

    Mears, Carolyn Lunsford

    2008-01-01

    Qualitative research methodologies comprise distinct traditions, each of which is based on its own assumptions and discrete methods for collecting, analyzing and reporting data. This paper examines a distinctive approach to qualitative research that was employed in a recent study to open a gateway to understanding the impact of the shootings at…

  3. Globalization, Open Access Publishing, and the Disappearance of Print: Threat or Opportunity?

    NASA Astrophysics Data System (ADS)

    Blom, J. J.

    Academic publishing is changing rapidly as a result of mutually dependent developments. Electronic publishing was born through the emergence of the Internet. The Internet has accelerated globalization, which in turn has enhanced the consolidation of commercial publishing houses and the collaboration between libraries. Old business models are being replaced by new business models, such as open access publishing. The familiar print format is disappearing for journals and perhaps for books. This chapter presents an overview of these developments and addresses potential threats and opportunities to the parties involved in publishing.

  4. Toward an Open-Access Global Database for Mapping, Control, and Surveillance of Neglected Tropical Diseases

    PubMed Central

    Hürlimann, Eveline; Schur, Nadine; Boutsika, Konstantina; Stensgaard, Anna-Sofie; Laserna de Himpsl, Maiti; Ziegelbauer, Kathrin; Laizer, Nassor; Camenzind, Lukas; Di Pasquale, Aurelio; Ekpo, Uwem F.; Simoonga, Christopher; Mushinge, Gabriel; Saarnak, Christopher F. L.; Utzinger, Jürg; Kristensen, Thomas K.; Vounatsou, Penelope

    2011-01-01

    Background After many years of general neglect, interest has grown and efforts came under way for the mapping, control, surveillance, and eventual elimination of neglected tropical diseases (NTDs). Disease risk estimates are a key feature to target control interventions, and serve as a benchmark for monitoring and evaluation. What is currently missing is a georeferenced global database for NTDs providing open-access to the available survey data that is constantly updated and can be utilized by researchers and disease control managers to support other relevant stakeholders. We describe the steps taken toward the development of such a database that can be employed for spatial disease risk modeling and control of NTDs. Methodology With an emphasis on schistosomiasis in Africa, we systematically searched the literature (peer-reviewed journals and ‘grey literature’), contacted Ministries of Health and research institutions in schistosomiasis-endemic countries for location-specific prevalence data and survey details (e.g., study population, year of survey and diagnostic techniques). The data were extracted, georeferenced, and stored in a MySQL database with a web interface allowing free database access and data management. Principal Findings At the beginning of 2011, our database contained more than 12,000 georeferenced schistosomiasis survey locations from 35 African countries available under http://www.gntd.org. Currently, the database is expanded to a global repository, including a host of other NTDs, e.g. soil-transmitted helminthiasis and leishmaniasis. Conclusions An open-access, spatially explicit NTD database offers unique opportunities for disease risk modeling, targeting control interventions, disease monitoring, and surveillance. Moreover, it allows for detailed geostatistical analyses of disease distribution in space and time. With an initial focus on schistosomiasis in Africa, we demonstrate the proof-of-concept that the establishment and running of a

  5. Toward an open-access global database for mapping, control, and surveillance of neglected tropical diseases.

    PubMed

    Hürlimann, Eveline; Schur, Nadine; Boutsika, Konstantina; Stensgaard, Anna-Sofie; Laserna de Himpsl, Maiti; Ziegelbauer, Kathrin; Laizer, Nassor; Camenzind, Lukas; Di Pasquale, Aurelio; Ekpo, Uwem F; Simoonga, Christopher; Mushinge, Gabriel; Saarnak, Christopher F L; Utzinger, Jürg; Kristensen, Thomas K; Vounatsou, Penelope

    2011-12-01

    After many years of general neglect, interest has grown and efforts came under way for the mapping, control, surveillance, and eventual elimination of neglected tropical diseases (NTDs). Disease risk estimates are a key feature to target control interventions, and serve as a benchmark for monitoring and evaluation. What is currently missing is a georeferenced global database for NTDs providing open-access to the available survey data that is constantly updated and can be utilized by researchers and disease control managers to support other relevant stakeholders. We describe the steps taken toward the development of such a database that can be employed for spatial disease risk modeling and control of NTDs. With an emphasis on schistosomiasis in Africa, we systematically searched the literature (peer-reviewed journals and 'grey literature'), contacted Ministries of Health and research institutions in schistosomiasis-endemic countries for location-specific prevalence data and survey details (e.g., study population, year of survey and diagnostic techniques). The data were extracted, georeferenced, and stored in a MySQL database with a web interface allowing free database access and data management. At the beginning of 2011, our database contained more than 12,000 georeferenced schistosomiasis survey locations from 35 African countries available under http://www.gntd.org. Currently, the database is expanded to a global repository, including a host of other NTDs, e.g. soil-transmitted helminthiasis and leishmaniasis. An open-access, spatially explicit NTD database offers unique opportunities for disease risk modeling, targeting control interventions, disease monitoring, and surveillance. Moreover, it allows for detailed geostatistical analyses of disease distribution in space and time. With an initial focus on schistosomiasis in Africa, we demonstrate the proof-of-concept that the establishment and running of a global NTD database is feasible and should be expanded

  6. Performance of Wireless Unattended Sensor Network in Maritime Applications

    DTIC Science & Technology

    2007-06-01

    longevity. Crossbow Technologies produces a number of gateways for use with their motes which include the MIB510, the MIB600 and the Stargate . The...MIB510 and MIB600 gateways require interface directly with a PC while he Stargate gateway interfaces remotely using the IEEE 802.11 standard for access...dedicated PC is unfeasible, the Stargate gateway allows remote access using the IEEE 802.11 standard. This can be accomplished via a Personal Computer

  7. Success in Gateway Business Courses: What Matters and What Can We Do?

    ERIC Educational Resources Information Center

    Berry, Tom; Cook, Lori; Hill, Nancy Thorley; Stevens, Kevin T.

    2013-01-01

    Introductory business classes, particularly those with a quantitative emphasis, can often serve as a barrier to students rather than as a gateway. This study looks at how study skills, aptitude, and external factors affect classroom performance. We examine whether, when, how, and how much students read their textbook. We also look at selected deep…

  8. The digital divide: Trends in global mobile and broadband Internet access from 2000–2010

    PubMed Central

    Ronquillo, Charlene; Currie, Leanne

    2012-01-01

    The digital divide is described as the gap between those who do and do not have access to digital information and communications technologies (ICT). ICTs are viewed as an indicator of infrastructure and potential for development, and are a growing platform for health information and services delivery. This study compares the penetration of mobile and broadband Internet technologies by global region from 2000 to 2010. Results illustrate the rapid growth of mobile cellular telephone subscriptions in all global regions with trends suggesting a continued increase. Little to modest gains were made in fixed broadband Internet subscriptions globally. There is a growing popularity of mobile subscriptions with use of data communications, exceeding the numbers of fixed Internet subscriptions. This comparison reveals current strengths that can be built on and highlights the importance of awareness of global trends and using such knowledge to inform design and delivery of ICT-based health services. PMID:24199118

  9. Lunar Heat Flux Measurements Enabled by a Microwave Radiometer Aboard the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Siegler, M.; Ruf, C.; Putzig, N.; Morgan, G.; Hayne, P.; Paige, D.; Nagihara, S.; Weber, R.

    2018-02-01

    We would like to present a concept to use the Deep Space Gateway as a platform for constraining the geothermal heat production, surface, and near-surface rocks, and dielectric properties of the Moon from orbit with passive microwave radiometery.

  10. Basic and Applied Algal Life Support System Research on Board the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Niederwieser, T.; Zea, L.; Anthony, J.; Stodieck, L.

    2018-02-01

    We study the effect of long-term preservation methods on DNA damage of algal cultures for BLSS applications. In a secondary step, the Deep Space Gateway serves as a technology demonstration platform for algal photobioreactors in intermittently occupied habitats.

  11. Racial Disparities In Geographic Access To Primary Care In Philadelphia.

    PubMed

    Brown, Elizabeth J; Polsky, Daniel; Barbu, Corentin M; Seymour, Jane W; Grande, David

    2016-08-01

    Primary care is often thought of as the gateway to improved health outcomes and can lead to more efficient use of health care resources. Because of primary care's cardinal importance, adequate access is an important health policy priority. In densely populated urban areas, spatial access to primary care providers across neighborhoods is poorly understood. We examined spatial variation in primary care access in Philadelphia, Pennsylvania. We calculated ratios of adults per primary care provider for each census tract and included buffer zones based on prespecified drive times around each tract. We found that the average ratio was 1,073; the supply of primary care providers varied widely across census tracts, ranging from 105 to 10,321. We identified six areas of Philadelphia that have much lower spatial accessibility to primary care relative to the rest of the city. After adjustment for sociodemographic and insurance characteristics, the odds of being in a low-access area were twenty-eight times greater for census tracts with a high proportion of African Americans than in tracts with a low proportion of African Americans. Project HOPE—The People-to-People Health Foundation, Inc.

  12. Global policy and access to new hepatitis C therapies for people who inject drugs.

    PubMed

    Doyle, Joseph S; Aspinall, Esther J; Hutchinson, Sharon J; Quinn, Brendan; Gore, Charles; Wiktor, Stefan Z; Hellard, Margaret E

    2015-11-01

    People who inject drugs (PWID) are disproportionately affected by hepatitis C virus (HCV). This review outlines policy recommendations made in the 2014 World Health Organisation (WHO) Guidelines on Screening, Care and Treatment of HCV and their relevance to PWID. It also canvasses issues that will affect translation of these global guidelines into practice. The first global HCV guidelines released by WHO have recently advocated targeted HCV testing for PWID, assessment of liver disease and support for alcohol reduction during care. They also strongly advocate treatment using currently licensed direct-acting antiviral agents for all individuals, in particular PWID as a key affected population. New HCV treatment regimens have the potential to cure more than 90% of treated individuals. Scaling-up treatment among PWID has the potential to improve individual and population health by reducing HCV transmission, improving quality of life and supporting behaviour modifications that lead to less risk-taking over time. PWID face several barriers to accessing HCV care and treatment that need to be overcome. Testing services need re-orientation toward PWID, individuals need to be informed of their results and provided with direct linkage to ongoing care. Health services need to provide care in the community using simpler, cheaper and more accessible modes of delivery. Healthcare costs and pharmaceutical costs need to be minimised so PWID, who are highly marginalised, can access HCV treatment. Sustained scale-up of treatment for PWID could simultaneously improve individual health and achieve the goal of eliminating HCV transmission among this high-risk and vulnerable group. Copyright © 2015. Published by Elsevier B.V.

  13. An Assessment of the Adult Learners' Needs at Gateway Community-Technical College.

    ERIC Educational Resources Information Center

    Luna, Wilson

    A study was conducted to assess the needs of adult learners at Gateway Community-Technical College (GCTC), in North Haven, Connecticut. An extended literature review resulted the choice of the three-part Adult Learner Needs Assessment Survey (ALNAS). In spring 1993, the ALNAS was administered to adult learners in classes at GCTC, resulting in 400…

  14. Factors Affecting Student Academic Success in Gateway Courses at Northern Arizona University

    ERIC Educational Resources Information Center

    Benford, Russell; Gess-Newsome, Julie

    2006-01-01

    Students in gateway business, math, and science courses at Northern Arizona University receive non-passing grades (grades of D, F, and W) at high rates. To identify possible trends in demographic groups that receive DFWs and to investigate why students receive DFWs in these courses, a student survey was administered to 719 students in 7 gateway…

  15. GATEWAY Demonstrations: OLED Lighting in the Offices of Aurora Lighting Design, Inc.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, Naomi J.

    At the offices of Aurora Lighting Design, Inc., in Grayslake, IL, the GATEWAY program conducted its first investigation involving OLED lighting. The project experienced several challenges, but also highlighted a number of promising attributes – which indicate that with continued improvements in efficacy, longevity, size, and flexibility, OLEDs could provide a new tool for creative and effective lighting.

  16. The Gateway Paper--context and configuration of the proposed health reforms in Pakistan.

    PubMed

    Nishtar, Sania

    2006-12-01

    As an opening of a dialogue on health reforms in Pakistan, the Gateway Paper presents a viewpoint on its proposed directions making a strong case for systems reforms, which need to scope beyond the healthcare system. Positioning the reform process to strengthen Pakistan's health policy cycle, the paper articulates a roadmap for a paradigm shift to achieve health outcomes in Pakistan with major structural reorganization within the health system. The proposed reform points in the four areas namely, reforms within the health sector, overarching measures, reconfiguration of health within an inter-sectoral scope and generating evidence for reforms. Reforms within the health sector focus on developing new models of service delivery and health financing which can enable the state to leverage the private sector outreach to deliver health-related public goods on the one hand and maximize the outreach of the State's health care delivery mechanisms through mainstreaming the role of the private sector on the other, albeit with safeguards. In addition, these call for strengthening the stewardship role to regulate these arrangements. The second area of reform focuses on overarching measures; these include developing frameworks for public-private partnerships which will enable the bringing together of organizations with the mandate to offer public goods and those that could facilitate this goal through the provision of resources, technical expertise or outreach; mainstreaming health into the country's social protection strategy in order to address issues of access and affordability for the poor and introducing civil service and public service reform focused on good governance, accountability, breakdown of institutional corruption which are critical to improving health outcomes. The third area of reform involves broadening health to its inter-sectoral scope, redefinition of objectives and targets within the health sector and garnering support from across the sectors to forester

  17. Opening a Gateway to College Access: Algebra at the Right Time. Research Brief

    ERIC Educational Resources Information Center

    Snipes, Jason; Finkelstein, Neal

    2015-01-01

    Four years of math in high school, with a strong foundation in algebra that builds from middle school, is key to higher education access. Therefore, ensuring that middle and high school students succeed in math--and in algebra in particular--is an important issue for policy and practice. This research brief examines three recent Regional…

  18. Low-Energy Cosmic Rays: Radiation Environment Studies and Astrophysics on the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Losekamm, M. J.; Berger, T.

    2018-02-01

    The Deep Space Gateway will be ideally located to investigate the cosmic radiation that astronauts are subjected to in deep space and to help shed light on one of the most intriguing astrophysical mysteries of today: What is the universe made of?

  19. 76 FR 32364 - Collaboration in Regulatory Science and Capacity To Advance Global Access to Safe Vaccines and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-06

    ...] Collaboration in Regulatory Science and Capacity To Advance Global Access to Safe Vaccines and Biologicals... and other biologicals that meet international standards. The goal of FDA's Center for Biologics... oversight of influenza and other vaccines and biologicals by supporting analysis, synthesis, and application...

  20. The Encyclopedia of Life v2: Providing Global Access to Knowledge About Life on Earth

    PubMed Central

    2014-01-01

    Abstract The Encyclopedia of Life (EOL, http://eol.org) aims to provide unprecedented global access to a broad range of information about life on Earth. It currently contains 3.5 million distinct pages for taxa and provides content for 1.3 million of those pages. The content is primarily contributed by EOL content partners (providers) that have a more limited geographic, taxonomic or topical scope. EOL aggregates these data and automatically integrates them based on associated scientific names and other classification information. EOL also provides interfaces for curation and direct content addition. All materials in EOL are either in the public domain or licensed under a Creative Commons license. In addition to the web interface, EOL is also accessible through an Application Programming Interface. In this paper, we review recent developments added for Version 2 of the web site and subsequent releases through Version 2.2, which have made EOL more engaging, personal, accessible and internationalizable. We outline the core features and technical architecture of the system. We summarize milestones achieved so far by EOL to present results of the current system implementation and establish benchmarks upon which to judge future improvements. We have shown that it is possible to successfully integrate large amounts of descriptive biodiversity data from diverse sources into a robust, standards-based, dynamic, and scalable infrastructure. Increasing global participation and the emergence of EOL-powered applications demonstrate that EOL is becoming a significant resource for anyone interested in biological diversity. PMID:24891832

  1. GATEWAY Demonstrations: OLED Lighting in the Offices of DeJoy, Knauf & Blood, LLP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, Naomi J.

    At the offices of the accounting firm of DeJoy, Knauf & Blood, LLP in Rochester, NY, the GATEWAY program evaluated a new lighting system that incorporates a number of different OLED luminaires. Evaluation of the OLED products included efficacy performance, field measurements of panel color, flicker measurements, and staff feedback.

  2. MultiSite Gateway-Compatible Cell Type-Specific Gene-Inducible System for Plants1[OPEN

    PubMed Central

    Siligato, Riccardo; Wang, Xin; Yadav, Shri Ram; Lehesranta, Satu; Ma, Guojie; Ursache, Robertas; Sevilem, Iris; Zhang, Jing; Gorte, Maartje; Prasad, Kalika; Heidstra, Renze

    2016-01-01

    A powerful method to study gene function is expression or overexpression in an inducible, cell type-specific system followed by observation of consequent phenotypic changes and visualization of linked reporters in the target tissue. Multiple inducible gene overexpression systems have been developed for plants, but very few of these combine plant selection markers, control of expression domains, access to multiple promoters and protein fusion reporters, chemical induction, and high-throughput cloning capabilities. Here, we introduce a MultiSite Gateway-compatible inducible system for Arabidopsis (Arabidopsis thaliana) plants that provides the capability to generate such constructs in a single cloning step. The system is based on the tightly controlled, estrogen-inducible XVE system. We demonstrate that the transformants generated with this system exhibit the expected cell type-specific expression, similar to what is observed with constitutively expressed native promoters. With this new system, cloning of inducible constructs is no longer limited to a few special cases but can be used as a standard approach when gene function is studied. In addition, we present a set of entry clones consisting of histochemical and fluorescent reporter variants designed for gene and promoter expression studies. PMID:26644504

  3. Optical gateway for intelligent buildings: a new open-up window to the optical fibre sensors market?

    NASA Astrophysics Data System (ADS)

    Fernandez-Valdivielso, Carlos; Matias, Ignacio R.; Arregui, Francisco J.; Bariain, Candido; Lopez-Amo, Manuel

    2004-06-01

    This paper presents the first optical fiber sensor gateway for integrating these special measurement devices in Home Automation Systems, concretely in those buildings that use the KNX European Intelligent Buildings Standard.

  4. Tactical Network Load Balancing in Multi-Gateway Wireless Sensor Networks

    DTIC Science & Technology

    2013-12-01

    writeup scrsz = get( 0 ,’ScreenSize’); %Creation of the random Sensor Network fig = figure(1); set(fig, ’Position’,[1 scrsz( 4 )*.25 scrsz(3)*.7...thesis writeup scrsz = get( 0 ,’ScreenSize’); %Creation of the random Sensor Network fig = figure(1); set(fig, ’Position’,[1 scrsz( 4 )*.25 scrsz(3)*.7...TYPE AND DATES COVERED Master’s Thesis 4 . TITLE AND SUBTITLE TACTICAL NETWORK LOAD BALANCING IN MULTI-GATEWAY WIRELESS SENSOR NETWORKS 5

  5. 78 FR 47410 - General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ...] General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area, New... (NPS) is releasing a Draft Environmental Impact Statement (DEIS) for the General Management Plan (GMP... alternatives to guide the management of the site over the next 20 years. The NPS preferred alternative...

  6. Accelerating global access to plant diversity information.

    PubMed

    Lughadha, Eimear Nic; Miller, Chuck

    2009-11-01

    Botanic gardens play key roles in the development and dissemination of plant information resources. Drivers for change have included progress in information technology, growing public expectations of electronic access and international conservation policy. Great advances have been made in the quantity, quality and accessibility of plant information in digital form and the extent to which information from multiple providers can be accessed through a single portal. However, significant challenges remain to be addressed in making botanic gardens resources maximally accessible and impactful, not least the overwhelming volume of material which still awaits digitisation. The year 2010 represents an opportunity for botanic gardens to showcase their collaborative achievements in delivery of electronic plant information and reinforce their relevance to pressing environmental issues.

  7. Knowledge sharing in global health research - the impact, uptake and cost of open access to scholarly literature.

    PubMed

    Smith, Elise; Haustein, Stefanie; Mongeon, Philippe; Shu, Fei; Ridde, Valéry; Larivière, Vincent

    2017-08-29

    In 1982, the Annals of Virology published a paper showing how Liberia has a highly endemic potential of Ebola warning health authorities of the risk for potential outbreaks; this journal is only available by subscription. Limiting the accessibility of such knowledge may have reduced information propagation toward public health actors who were indeed surprised by and unprepared for the 2014 epidemic. Open access (OA) publication can allow for increased access to global health research (GHR). Our study aims to assess the use, cost and impact of OA diffusion in the context of GHR. A total of 3366 research articles indexed under the Medical Heading Subject Heading "Global Health" published between 2010 and 2014 were retrieved using PubMed to (1) quantify the uptake of various types of OA, (2) estimate the article processing charges (APCs) of OA, and (3) analyse the relationship between different types of OA, their scholarly impact and gross national income per capita of citing countries. Most GHR publications are not available directly on the journal's website (69%). Further, 60.8% of researchers do not self-archive their work even when it is free and in keeping with journal policy. The total amount paid for APCs was estimated at US$1.7 million for 627 papers, with authors paying on average US$2732 per publication; 94% of APCs were paid to journals owned by the ten most prominent publication houses from high-income countries. Researchers from low- and middle-income countries are generally citing less expensive types of OA, while researchers in high-income countries are citing the most expensive OA. Although OA may help in building global research capacity in GHR, the majority of publications remain subscription only. It is logical and cost-efficient for institutions and researchers to promote OA by self-archiving publications of restricted access, as it not only allows research to be cited by a broader audience, it also augments citation rates. Although OA does not

  8. Authorial and institutional stratification in open access publishing: the case of global health research.

    PubMed

    Siler, Kyle; Haustein, Stefanie; Smith, Elise; Larivière, Vincent; Alperin, Juan Pablo

    2018-01-01

    Using a database of recent articles published in the field of Global Health research, we examine institutional sources of stratification in publishing access outcomes. Traditionally, the focus on inequality in scientific publishing has focused on prestige hierarchies in established print journals. This project examines stratification in contemporary publishing with a particular focus on subscription vs. various Open Access (OA) publishing options. Findings show that authors working at lower-ranked universities are more likely to publish in closed/paywalled outlets, and less likely to choose outlets that involve some sort of Article Processing Charge (APCs; gold or hybrid OA). We also analyze institutional differences and stratification in the APC costs paid in various journals. Authors affiliated with higher-ranked institutions, as well as hospitals and non-profit organizations pay relatively higher APCs for gold and hybrid OA publications. Results suggest that authors affiliated with high-ranked universities and well-funded institutions tend to have more resources to choose pay options with publishing. Our research suggests new professional hierarchies developing in contemporary publishing, where various OA publishing options are becoming increasingly prominent. Just as there is stratification in institutional representation between different types of publishing access, there is also inequality within access types.

  9. Authorial and institutional stratification in open access publishing: the case of global health research

    PubMed Central

    Haustein, Stefanie; Smith, Elise; Larivière, Vincent; Alperin, Juan Pablo

    2018-01-01

    Using a database of recent articles published in the field of Global Health research, we examine institutional sources of stratification in publishing access outcomes. Traditionally, the focus on inequality in scientific publishing has focused on prestige hierarchies in established print journals. This project examines stratification in contemporary publishing with a particular focus on subscription vs. various Open Access (OA) publishing options. Findings show that authors working at lower-ranked universities are more likely to publish in closed/paywalled outlets, and less likely to choose outlets that involve some sort of Article Processing Charge (APCs; gold or hybrid OA). We also analyze institutional differences and stratification in the APC costs paid in various journals. Authors affiliated with higher-ranked institutions, as well as hospitals and non-profit organizations pay relatively higher APCs for gold and hybrid OA publications. Results suggest that authors affiliated with high-ranked universities and well-funded institutions tend to have more resources to choose pay options with publishing. Our research suggests new professional hierarchies developing in contemporary publishing, where various OA publishing options are becoming increasingly prominent. Just as there is stratification in institutional representation between different types of publishing access, there is also inequality within access types. PMID:29479492

  10. Physician Acceptance of Gateway to Care at Irwin Army Community Hospital

    DTIC Science & Technology

    1992-07-27

    frontier cavalry post once commanded by General George Armstrong Custer. Today it is the home of almost 20,000 soldiers of the Big Red One, First Infantry...especially important for the future. Physicians, as key "players" in healthcare organizations, are also key to the success of Gateway to Care. Kotler and...research (3rd ed.). New York: Holt. Physician Acceptance 32 Kotler , P., & Clarke, R. (1987). Marketing for health care organizations. Englewood Cliffs

  11. Baker-Barry Tunnel Lighting: Evaluation of a Potential GATEWAY Demonstrations Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tuenge, Jason R.

    2011-06-01

    The U.S. Department of Energy (DOE) is evaluating the Baker-Barry Tunnel as a potential GATEWAY Demonstrations project for deployment of solid-state lighting (SSL) technology. The National Park Service (NPS) views this project as a possible proving ground and template for implementation of light-emitting diode (LED) luminaires in other NPS tunnels, thereby expanding the estimated 40% energy savings from 132 MWh/yr for this tunnel to a much larger figure national

  12. Seal of transparency heritage in the CISMeF quality-controlled health gateway

    PubMed Central

    Darmoni, SJ; Dahamna, B; Roth-Berghofer, Thomas R

    2004-01-01

    Background It is an absolute necessity to continually assess the quality of health information on the Internet. Quality-controlled subject gateways are Internet services which apply a selected set of targeted measures to support systematic resource discovery. Methods The CISMeF health gateway became a contributor to the MedCIRCLE project to evaluate 270 health information providers. The transparency heritage consists of using the evaluation performed on providers that are referenced in the CISMeF catalogue for evaluating the documents they publish, thus passing on the transparency label from the publishers to their documents. Results Each site rated in CISMeF has a record in the CISMeF database that generates an RDF into HTML file. The search tool Doc'CISMeF displays information originating from every publisher evaluated with a specific MedCIRCLE button, which is linked to the MedCIRCLE central repository. Starting with 270 websites, this trust heritage has led to 6,480 evaluated resources in CISMeF (49.8% of the 13,012 resources included in CISMeF). Conclusion With the MedCIRCLE project and transparency heritage, CISMeF became an explicit third party. PMID:15367332

  13. A PICKSC Science Gateway for enabling the common plasma physicist to run kinetic software

    NASA Astrophysics Data System (ADS)

    Hu, Q.; Winjum, B. J.; Zonca, A.; Youn, C.; Tsung, F. S.; Mori, W. B.

    2017-10-01

    Computer simulations offer tremendous opportunities for studying plasmas, ranging from simulations for students that illuminate fundamental educational concepts to research-level simulations that advance scientific knowledge. Nevertheless, there is a significant hurdle to using simulation tools. Users must navigate codes and software libraries, determine how to wrangle output into meaningful plots, and oftentimes confront a significant cyberinfrastructure with powerful computational resources. Science gateways offer a Web-based environment to run simulations without needing to learn or manage the underlying software and computing cyberinfrastructure. We discuss our progress on creating a Science Gateway for the Particle-in-Cell and Kinetic Simulation Software Center that enables users to easily run and analyze kinetic simulations with our software. We envision that this technology could benefit a wide range of plasma physicists, both in the use of our simulation tools as well as in its adaptation for running other plasma simulation software. Supported by NSF under Grant ACI-1339893 and by the UCLA Institute for Digital Research and Education.

  14. Improving access to care for children with mental disorders: a global perspective.

    PubMed

    Patel, Vikram; Kieling, Christian; Maulik, Pallab K; Divan, Gauri

    2013-05-01

    Developmental disabilities, emotional disorders and disruptive behaviour disorders are the leading mental health-related causes of the global burden of disease in children aged below 10 years. This article aims to address the treatment gap for child mental disorders through synthesising three bodies of evidence: the global evidence base on the treatment of these priority disorders; the barriers to implementation of this knowledge; and the innovative approaches taken to address these barriers and improve access to care. Our focus is on low-resource settings, which are mostly found in low- and middle-income countries (LMIC). Despite the evidence base on the burden of child mental disorders and their long-term consequences, and the recent mental health Gap Action Programme guidelines which testify to the effectiveness of a range of pharmacological and psychosocial interventions for these disorders, the vast majority of children in LMIC do not have access to these interventions. We identify three major barriers for the implementation of efficacious treatments: the lack of evidence on delivery of the treatments, the low levels of detection of child mental disorders and the shortage of skilled child mental health professionals. The evidence based on implementation, although weak, supports the use of screening measures for detection of probable disorders, coupled with a second-stage diagnostic assessment and the use of non-specialist workers in community and school settings for the delivery of psychosocial interventions. The most viable strategy to address the treatment gap is through the empowerment of existing human resources who are most intimately concerned with child care, including parents, through innovative technologies, such as mobile health, with the necessary skills for the detection and treatment of child mental disorders.

  15. Linking Gateway Technical College with Workforce Development: The SC Johnson-A Family Company Story.

    ERIC Educational Resources Information Center

    Knudson, Edward

    2004-01-01

    Seven years ago, SC Johnson--A Family Company approached Gateway Technical College with a need to further strengthen their incumbent workforce's technical training and education. Retirements, brain drain, and competition for technical expertise were the forces driving SC Johnson to develop a comprehensive, flexible, and timely workplace education…

  16. GATEWAY Demonstrations: Trial Demonstration of Area Lighting Retrofit, Yuma Border Patrol, Yuma, Arizona

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilkerson, A. M.; McCullough, J. J.

    Along the Yuma Sector Border Patrol Area in Yuma, Arizona, the GATEWAY program conducted a trial demonstration in which the incumbent quartz metal halide area lighting was replaced with LED at three pole locations at the Yuma Sector Border Patrol Area in Yuma, Arizona. The retrofit was documented to better understand LED technology performance in high-temperature environments.

  17. Power is sweet: sugarcane in the global ethanol assemblage.

    PubMed

    Hollander, Gail

    2010-01-01

    New alliances between Brazil and the US for ethanol production, transport, and trade are revitalising and expanding the centuries -old sugarcane plantation system in the Americas. In this paper I adopt the concept of global assemblages, building on the work of Aihwa Ong, Stephen Collier, and Saskia Sassen, to draw the contours of an "ethanol assemblage," which includes states, corporations, growers, technologies, urban consumers, and rural communities and landscapes. Though important to conceptualise agrofuels as a global phenomenon, it is also necessary to recognise the distinct regional patterns that cohere around various aspects of this polymorphous industry. Therefore, I focus on alliances around sugarcane ethanol, paying particular attention to the role of Miami as a global city serving as a gateway to information, investment, and commodities for the public/private and national/transnational entities that are engaged in the hemispheric project of ethanol promotion, production and distribution.

  18. JOURNAL CLUB: Redefining the Radiology Curriculum in Medical School: Vertical Integration and Global Accessibility.

    PubMed

    Retrouvey, Michele; Trace, Anthony Paul; Goodmurphy, Craig W; Shaves, Sarah

    2018-01-01

    Radiology interconnects medical disciplines given that a working understanding of imaging is essential to clinicians of every specialty. Using online education, we created a globally accessible, web-based undergraduate medical radiology curriculum modeled after the National Medical Student Curriculum in Radiology program of the Alliance of Medical Student Educators in Radiology. Seventy-four radiology faculty-mentored video modules were produced, 50 of which were integrated into the 1st-year anatomy course. We administered tests to medical students before and after students saw the videos to assess the effectiveness of the modules. We surveyed students on their interests in pursuing radiology as a career before and after participating in this curriculum. On the preexamination questions, the mean score was 58.0%, which increased to 83.6% on the pair-matched imaging-related questions on the actual examination. Before participating in the new curriculum, 88% of students did not express an interest in radiology, and 9% were undecided about radiology as a future career. There was an increase in students who reported that they would definitely or most likely pursue a career in radiology (7%) after they had viewed the lectures. Radiology education is now available to a greater number of multidisciplinary learners worldwide. This project produced a comprehensive, globally accessible radiology curriculum in a self-paced, flexible learning format for new generations of physicians.

  19. Interhospital network system using the worldwide web and the common gateway interface.

    PubMed

    Oka, A; Harima, Y; Nakano, Y; Tanaka, Y; Watanabe, A; Kihara, H; Sawada, S

    1999-05-01

    We constructed an interhospital network system using the worldwide web (WWW) and the Common Gateway Interface (CGI). Original clinical images are digitized and stored as a database for educational and research purposes. Personal computers (PCs) are available for data treatment and browsing. Our system is simple, as digitized images are stored into a Unix server machine. Images of important and interesting clinical cases are selected and registered into the image database using CGI. The main image format is 8- or 12-bit Joint Photographic Experts Group (JPEG) image. Original clinical images are finally stored in CD-ROM using a CD recorder. The image viewer can browse all of the images for one case at once as thumbnail pictures; image quality can be selected depending on the user's purpose. Using the network system, clinical images of interesting cases can be rapidly transmitted and discussed with other related hospitals. Data transmission from relational hospitals takes 1 to 2 minutes per 500 Kbyte of data. More distant hospitals (e.g., Rakusai Hospital, Kyoto) takes 1 minute more. The mean number of accesses our image database in a recent 3-month period was 470. There is a total about 200 cases in our image database, acquired over the past 2 years. Our system is useful for communication and image treatment between hospitals and we will describe the elements of our system and image database.

  20. Maximizing Gateway-Course Improvement by Making the Whole Greater than the Sum of the Parts

    ERIC Educational Resources Information Center

    Koch, Andrew K.; Prystowsky, Richard J.; Scinta, Tony

    2017-01-01

    Drawing on systems theory, this chapter uses two different institutional examples to demonstrate the benefits of combining gateway-course improvement initiatives with other student success efforts so that the combined approach makes the whole greater than the simple sum of the pieces.

  1. Los Angeles-Gateway Freight Advanced Traveler Information System : final system design and architecture for FRATIS prototype.

    DOT National Transportation Integrated Search

    2013-05-01

    This Final Architecture and Design report has been prepared to describe the structure and design of all the system components for the LA-Gateway FRATIS Demonstration Project. More specifically, this document provides: Detailed descriptions of the...

  2. Smart home design for electronic devices monitoring based wireless gateway network using cisco packet tracer

    NASA Astrophysics Data System (ADS)

    Sihombing, Oloan; Zendrato, Niskarto; Laia, Yonata; Nababan, Marlince; Sitanggang, Delima; Purba, Windania; Batubara, Diarmansyah; Aisyah, Siti; Indra, Evta; Siregar, Saut

    2018-04-01

    In the era of technological development today, the technology has become the need for the life of today's society. One is needed to create a smart home in turning on and off electronic devices via smartphone. So far in turning off and turning the home electronic device is done by pressing the switch or remote button, so in control of electronic device control less effective. The home smart design is done by simulation concept by testing system, network configuration, and wireless home gateway computer network equipment required by a smart home network on cisco packet tracer using Internet Thing (IoT) control. In testing the IoT home network wireless network gateway system, multiple electronic devices can be controlled and monitored via smartphone based on predefined configuration conditions. With the Smart Ho me can potentially increase energy efficiency, decrease energy usage costs, control electronics and change the role of residents.

  3. Expanding global access to radiotherapy.

    PubMed

    Atun, Rifat; Jaffray, David A; Barton, Michael B; Bray, Freddie; Baumann, Michael; Vikram, Bhadrasain; Hanna, Timothy P; Knaul, Felicia M; Lievens, Yolande; Lui, Tracey Y M; Milosevic, Michael; O'Sullivan, Brian; Rodin, Danielle L; Rosenblatt, Eduardo; Van Dyk, Jacob; Yap, Mei Ling; Zubizarreta, Eduardo; Gospodarowicz, Mary

    2015-09-01

    Radiotherapy is a critical and inseparable component of comprehensive cancer treatment and care. For many of the most common cancers in low-income and middle-income countries, radiotherapy is essential for effective treatment. In high-income countries, radiotherapy is used in more than half of all cases of cancer to cure localised disease, palliate symptoms, and control disease in incurable cancers. Yet, in planning and building treatment capacity for cancer, radiotherapy is frequently the last resource to be considered. Consequently, worldwide access to radiotherapy is unacceptably low. We present a new body of evidence that quantifies the worldwide coverage of radiotherapy services by country. We show the shortfall in access to radiotherapy by country and globally for 2015-35 based on current and projected need, and show substantial health and economic benefits to investing in radiotherapy. The cost of scaling up radiotherapy in the nominal model in 2015-35 is US$26·6 billion in low-income countries, $62·6 billion in lower-middle-income countries, and $94·8 billion in upper-middle-income countries, which amounts to $184·0 billion across all low-income and middle-income countries. In the efficiency model the costs were lower: $14·1 billion in low-income, $33·3 billion in lower-middle-income, and $49·4 billion in upper-middle-income countries-a total of $96·8 billion. Scale-up of radiotherapy capacity in 2015-35 from current levels could lead to saving of 26·9 million life-years in low-income and middle-income countries over the lifetime of the patients who received treatment. The economic benefits of investment in radiotherapy are very substantial. Using the nominal cost model could produce a net benefit of $278·1 billion in 2015-35 ($265·2 million in low-income countries, $38·5 billion in lower-middle-income countries, and $239·3 billion in upper-middle-income countries). Investment in the efficiency model would produce in the same period an even

  4. Supporting Ecological Research With a Flexible Satellite Sensornet Gateway

    NASA Astrophysics Data System (ADS)

    Silva, F.; Rundel, P. W.; Graham, E. A.; Falk, A.; Ye, W.; Pradkin, Y.; Deschon, A.; Bhatt, S.; McHenry, T.

    2007-12-01

    Wireless sensor networks are a promising technology for ecological research due to their capability to make continuous and in-situ measurements. However, there are some challenges for the wide adoption of this technology by scientists, who may have various research focuses. First, the observation system needs to be rapidly and easily deployable at different remote locations. Second, the system needs to be flexible enough to meet the requirements of different applications and easily reconfigurable by scientists, who may not always be technology experts. To address these challenges, we designed and implemented a flexible satellite gateway for using sensor networks. Our first prototype is being deployed at Stunt Ranch in the Santa Monica Mountains to support biological research at UCLA. In this joint USC/ISI-UCLA deployment, scientists are interested in a long-term investigation of the influence of the 2006-07 southern California drought conditions on the water relations of important chaparral shrub and tree species that differ in their depth of rooting. Rainfall over this past hydrologic year in southern California has been less than 25% of normal, making it the driest year on record. In addition to core measurements of air temperature, relative humidity, wind speed, solar irradiance, rainfall, and soil moisture, we use constant-heating sap flow sensors to continuously monitor the flow of water through the xylem of replicated stems of four species to compare their access to soil moisture with plant water stress. Our gateway consists of a front-end data acquisition system and a back-end data storage system, connected by a long-haul satellite communication link. At the front-end, all environmental sensors are connected to a Compact RIO, a rugged data acquisition platform developed by National Instruments. Sap flow sensors are deployed in several locations that are 20 to 50 meters away from the Compact RIO. At each plant, a Hobo datalogger is used to collect sap flow

  5. A Squandered Resource: The Divestment of Mexican Parental Involvement in a New Gateway State

    ERIC Educational Resources Information Center

    Petrone, Eleanor

    2016-01-01

    Parental involvement plays an important role in the academic success of children. Schools in new gateway states where there has not been a longstanding tradition of immigration often lack the cultural knowledge and linguistic resources necessary to serve immigrant youth and their families effectively. By examining the experiences of Mexican…

  6. Impact of Northern Hemisphere polar gateways on the Arctic Ocean climate during the latest Cretaceous as simulated by an Earth System Model.

    NASA Astrophysics Data System (ADS)

    Niezgodzki, Igor; Knorr, Gregor; Lohmann, Gerrit; Tyszka, Jarosław

    2017-04-01

    Using the Earth System Model COSMOS, we simulate the Late Cretaceous climate with different gateway configurations in the Arctic Ocean region under constant CO2 level of 1120 ppm (4 x pre-industrial). Based on the Maastrichtian paleogeography, we modify gateway configurations in the Arctic region according to different scenarios recorded from the Campanian - Maastrichtian ( 83-66 Ma). Our simulation with the Greenland-Norwegian Sea even as deep as 1.5 km in the Campanian produces consistent salinities in the Greenland-Norwegian Sea and in the surface Arctic Ocean, with the proxy-based salinity reconstructions. Towards the end of the Maastrichtian the gateway became shallower but didn't close entirely before the K-Pg boundary. During entire interval, the simulated salinity in the Arctic Ocean was well stratified, in agreement with the data. The surface ocean became progressively fresher, starting from the moderately brackish conditions in the Campanian to the (almost) freshwater conditions around the K-Pg boundary. Arctic gateways configuration changes cannot reproduce cooling trends as reconstructed by the proxy data during the Campanian - Maastrichtian interval. Our additional sensitivity tests with the different CO2 levels (1-6 x pre-industrial) and fixed (Maastrichtian) paleogeography show that a doubling of atmospheric CO2 concentration from 560 ppm to 1120 ppm results in an increase in the zonal mean surface air temperature in the polar regions by as high as 10°C. This suggests that the CO2 level decline, rather than gateway configuration changes, was responsible for the cooling trend toward the end of the Maastrichtian. The research was supported from the grant of the National Science Center in Poland based on the decision DEC-2012/07/N/ST10/03419.

  7. Los Angeles-Gateway Freight Advanced Traveler Information System : prototype development and small-scale demonstrations for FRATIS.

    DOT National Transportation Integrated Search

    2013-06-01

    This Demonstration Plan has been prepared to provide guidance and a common definition to all parties of the testing program that will be conducted for the LA-Gateway FRATIS Demonstration Project. More specifically, this document provides: Plannin...

  8. 76 FR 18294 - Receipt of Noise Compatibility Program and Request for Review; Kissimmee Gateway Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Receipt of Noise Compatibility... reviewing a proposed Noise Compatibility Program that was submitted for Kissimmee Gateway Airport under the provisions of 49 U.S.C. 47504 et seq. (the Aviation Safety and Noise Abatement Act hereinafter referred to as...

  9. Pre-Assessment and Peer Tutoring as Measures to Improve Performance in Gateway General Chemistry Classes

    ERIC Educational Resources Information Center

    Allenbaugh, R. J.; Herrera, K. M.

    2014-01-01

    Determining student readiness for gateway chemistry courses and providing underprepared students effective remediation are important as student bodies are growing increasingly diverse in their precollege preparation. The effectiveness of the ACT Mathematics Test and the Whimbey Analytical Skills Inventory (WASI) in predicting student success in…

  10. Utilizing the Deep Space Gateway to Characterize DNA Damage Due to Space Radiation and Repair Mechanisms

    NASA Astrophysics Data System (ADS)

    Zea, L.; Niederwieser, T.; Anthony, J.; Stodieck, L.

    2018-02-01

    The radiation environment experienced in the Deep Space Gateway enables the interrogation of DNA damage and repair mechanisms, which may serve to determine the likelihood and consequence of the high radiation risk to prolonged human presence beyond LEO.

  11. Earth science information: Planning for the integration and use of global change information

    NASA Technical Reports Server (NTRS)

    Lousma, Jack R.

    1992-01-01

    Activities and accomplishments of the first six months of the Consortium for International Earth Science Information Network (CIESIN's) 1992 technical program have focused on four main missions: (1) the development and implementation of plans for initiation of the Socioeconomic Data and Applications Center (SEDAC) as part of the EOSDIS Program; (2) the pursuit and development of a broad-based global change information cooperative by providing systems analysis and integration between natural science and social science data bases held by numerous federal agencies and other sources; (3) the fostering of scientific research into the human dimensions of global change and providing integration between natural science and social science data and information; and (4) the serving of CIESIN as a gateway for global change data and information distribution through development of the Global Change Research Information Office and other comprehensive knowledge sharing systems.

  12. Out of the Depths Have I Cried: Aesthetic Opposition at the Gateway to Auschwitz

    ERIC Educational Resources Information Center

    Javore, Barbara B.

    2015-01-01

    Terezin, the gateway to Auschwitz, a town commandeered by the Nazis to serve as a "model" relocation camp to demonstrate the Third Reich's generosity and kindness toward the Jews, was an elaborate hoax. In an environment where truth was twisted beyond recognition, artists, writers, actors, and musicians used their work to revive the…

  13. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2003-06-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity(R), the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: AdGVVEGF121.10, anakinra, andolast, anidulafungin, APC-2059, l-arginine hydrochloride, aripiprazole, arzoxifene hydrochloride, asimadoline; Bexarotene, bimatoprost, bimosiamose, bizelesin, BMS-188667, botulinum toxin type B, bromfenac sodium, bryostatin 1; Cannabidiol, cariporide mesilate, CCI-1004, CDP-571, cerivastatin sodium, clevudine; Dalbavancin, darbepoetin alfa, decitabine, deligoparin sodium, diethylnorspermine, drotrecogin alfa (activated), DTaP-HBV-IPV/Hib-vaccine; E-5564, eculizumab, edodekin alfa, emtricitabine, enfuvirtide, (-)-epigallocatechin gallate, eplerenone, esomeprazole magnesium, etaquine, etoricoxib, ezetimibe; Fesoterodine, fipamezole hydrochloride, fondaparinux sodium, fosamprenavir calcium, frovatriptan, fulvestrant; Gadofosveset sodium, galiximab, ghrelin (human), glufosfamide; Homoharringtonine; Idraparinux sodium, imatinib mesylate, INS-37217; KRN-7000; L-651582, lafutidine, lanthanum carbonate, lenercept, levetiracetam, lusupultide; Magnesium sulfate, melatonin, mepolizumab, midostaurin, morphine hydrochloride, mozavaptan; Natalizumab, nesiritide; OPC-51803, oregovomab, oritavancin; Peginterferon alfa-2(a), pleconaril, plevitrexed, prasterone, pregabalin; Ranibizumab, Ro-31-7453, roxifiban acetate, rubitecan; SCV-07, SHL-749, sho-saiko-to, soblidotin, solifenacin succinate; Tegaserod maleate, telithromycin, tenecteplase, theraCIM, tipifarnib, travoprost; Valdecoxib, vardenafil hydrochloride hydrate, voriconazole; Ximelagatran; Ziprasidone hydrochloride, ZYC-00101. (c) 2003 Prous Science. All rights reserved.

  14. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2002-05-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables can be retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: Abacavir sulfate, abarelix, abciximab, acarbose, alefacept, alteplase, amisulpride, amoxicillin trihydrate, apomorphine hydrochloride, aprepitant, argatroban monohydrate, aspirin, atenolol; Betamethasone dipropionate, betamethasone valerate, bicalutamide, bleomycin sulfate; Calcium carbonate, candesartan cilexetil, celecoxib, cetirizine hydrochloride, cisplatin, clarithromycin, clavulanate potassium, clomethiazole edisilate, clopidogrel hydrogensulfate, cyclophosphamide, chorionic gonadotropin (human); Dalteparin sodium, desloratadine, dexamethasone, doxorubicin, DPC-083; Efalizumab, efavirenz, enoxaparin sodium, eprosartan mesilate, etanercept, etoposide, ezetimibe; Faropenem daloxate, fenofibrate, fluocinolone acetonide, flutamide, fluvastatin sodium, follitropin beta, fondaparinux sodium; Gabapentin, glibenclamide, goserelin, granisetron hydrochloride; Haloperidol, hydrochlorothiazide; Imiquimod, interferon beta-1a, irbesartan, iseganan hydrochloride; L-758298, lamivudine, lanoteplase, leflunomide, leuprorelin acetate, loratadine, losartan potassium; Melagatran, metformin hydrochloride, methotrexate, metronidazole, micafungin sodium, mitoxantrone hydrochloride; Nelfinavir mesilate, neutral insulin injection, nizatidine; Olopatadine hydrochloride, omeprazole, ondansetron hydrochloride; Pamidronate sodium, paracetamol, paroxetine hydrochloride, perindopril, pimecrolimus, pioglitazone hydrochloride, piroxicam, pleconaril, pralmorelin, pravastatin sodium, prednisolone, prednisone, propofol; Raloxifene hydrochloride, ranpirnase, remifentanil hydrochloride, risedronate sodium, risperidone, rofecoxib, ropinirole

  15. Selecting Lentil Accessions for Global Selenium Biofortification.

    PubMed

    Thavarajah, Dil; Abare, Alex; Mapa, Indika; Coyne, Clarice J; Thavarajah, Pushparajah; Kumar, Shiv

    2017-08-26

    The biofortification of lentil ( Lens culinaris Medikus.) has the potential to provide adequate daily selenium (Se) to human diets. The objectives of this study were to (1) determine how low-dose Se fertilizer application at germination affects seedling biomass, antioxidant activity, and Se uptake of 26 cultivated lentil genotypes; and (2) quantify the seed Se concentration of 191 lentil wild accessions grown in Terbol, Lebanon. A germination study was conducted with two Se treatments [0 (control) and 30 kg of Se/ha] with three replicates. A separate field study was conducted in Lebanon for wild accessions without Se fertilizer. Among cultivated lentil accessions, PI533690 and PI533693 showed >100% biomass increase vs. Se addition significantly increased seedling Se uptake, with the greatest uptake (6.2 µg g -1 ) by PI320937 and the least uptake (1.1 µg g -1 ) by W627780. Seed Se concentrations of wild accessions ranged from 0 to 2.5 µg g -1 ; accessions originating from Syria (0-2.5 µg g -1 ) and Turkey (0-2.4 µg g -1 ) had the highest seed Se. Frequency distribution analysis revealed that seed Se for 63% of accessions was between 0.25 and 0.75 µg g -1 , and thus a single 50 g serving of lentil has the potential to provide adequate dietary Se (20-60% of daily recommended daily allowance). As such, Se application during plant growth for certain lentil genotypes grown in low Se soils may be a sustainable Se biofortification solution to increase seed Se concentration. Incorporating a diverse panel of lentil wild germplasm into Se biofortification programs will increase genetic diversity for effective genetic mapping for increased lentil seed Se nutrition and plant productivity.

  16. Selecting Lentil Accessions for Global Selenium Biofortification

    PubMed Central

    Thavarajah, Dil; Abare, Alex; Mapa, Indika; Coyne, Clarice J.; Thavarajah, Pushparajah; Kumar, Shiv

    2017-01-01

    The biofortification of lentil (Lens culinaris Medikus.) has the potential to provide adequate daily selenium (Se) to human diets. The objectives of this study were to (1) determine how low-dose Se fertilizer application at germination affects seedling biomass, antioxidant activity, and Se uptake of 26 cultivated lentil genotypes; and (2) quantify the seed Se concentration of 191 lentil wild accessions grown in Terbol, Lebanon. A germination study was conducted with two Se treatments [0 (control) and 30 kg of Se/ha] with three replicates. A separate field study was conducted in Lebanon for wild accessions without Se fertilizer. Among cultivated lentil accessions, PI533690 and PI533693 showed >100% biomass increase vs. controls. Se addition significantly increased seedling Se uptake, with the greatest uptake (6.2 µg g−1) by PI320937 and the least uptake (1.1 µg g−1) by W627780. Seed Se concentrations of wild accessions ranged from 0 to 2.5 µg g−1; accessions originating from Syria (0–2.5 µg g−1) and Turkey (0–2.4 µg g−1) had the highest seed Se. Frequency distribution analysis revealed that seed Se for 63% of accessions was between 0.25 and 0.75 µg g−1, and thus a single 50 g serving of lentil has the potential to provide adequate dietary Se (20–60% of daily recommended daily allowance). As such, Se application during plant growth for certain lentil genotypes grown in low Se soils may be a sustainable Se biofortification solution to increase seed Se concentration. Incorporating a diverse panel of lentil wild germplasm into Se biofortification programs will increase genetic diversity for effective genetic mapping for increased lentil seed Se nutrition and plant productivity. PMID:28846602

  17. Gateway National Recreational Area - Sandy Hook Unit : automated fee entrance plaza and intelligent transportation system technical requirements

    DOT National Transportation Integrated Search

    2009-01-01

    The Volpe National Transportation Systems Center (Volpe Center) is providing technical : support to Sandy Hook, a unit of the Gateway National Recreation Area, in the planning and : concept development for possible Intelligent Transportation Systems ...

  18. Radiometric Calibration of Earth Science Imagers Using HyCalCam on the Deep Space Gateway Platform

    NASA Astrophysics Data System (ADS)

    Butler, J. J.; Thome, K. J.

    2018-02-01

    HyCalCam, an SI-traceable imaging spectrometer on the Deep Space Gateway, acquires images of the Moon and Earth to characterize the lunar surface and terrestrial scenes for use as absolute calibration targets for on-orbit LEO and GEO sensors.

  19. Evaluation of R1-6 gateway treatment alternatives for pedestrian crossings : follow-up report : final report.

    DOT National Transportation Integrated Search

    2017-06-01

    Monthly follow-up data confirmed that permanent in roadway installations of the R1-6 gateway treatment led to an : increase in the percentage of drivers yielding to pedestrians at midblock and multilane urban and suburban locations : from 15% to 70% ...

  20. The NC3Rs gateway: Accelerating scientific discoveries with new 3Rs models and technologies.

    PubMed

    Percie du Sert, Nathalie; Robinson, Vicky

    2018-01-01

    This editorial introduces the NC3Rs gateway, which publishes articles and reviews on new models and technologies emerging from NC3Rs-funded research. The aim is to raise awareness about these approaches, increase confidence in their capability, and provide sufficient information to facilitate their uptake by others.

  1. Evaluation of R1-6 gateway treatment alternatives for pedestrian crossings : follow-up report : draft report.

    DOT National Transportation Integrated Search

    2016-12-01

    Monthly follow-up data confirmed that permanent in roadway installations of the R1-6 gateway treatment led to an increase in the percentage of drivers yielding to pedestrians at midblock and multilane urban and suburban locations from 15% to 70% and ...

  2. The Gateway Paper--financing health in Pakistan and its linkage with health reforms.

    PubMed

    Nishtar, Sania

    2006-12-01

    Pakistan currently principally uses three modes of financing health--taxation, out of pocket payments and donor contributions of which the latter is the least significant in terms of size. Less than 3.6% of the employees are covered under the social security scheme and there is a limited social protection mechanism, which collectively serves the health needs of 3.4% of the population. The main issues in health financing include low spending, lack of attention to alternate sources of financing and issues with fund mobilization and utilization. With respect to the first, health reforms proposed as part of the Gateway Paper make a strong case for promoting the reallocation of tax-based revenues and developing sustainable alternatives to low levels of public spending on health. With respect to alternative sources of health financing, the Gateway Paper lays stress on exploring policy options for private health insurance, broadening the base of Employees Social Security, creating a Federal Employees Social Security Programme, developing social health insurance within the framework of a broad-based social protection strategy, which scopes beyond the formally employed sector, establishing a widely inclusive safety net for the poor; mainstreaming philanthropic grants as a major source of health financing; developing a conducive tax configuration; generating greater corporate support for social sector causes within the framework of the concept of Corporate Social Responsibility and developing cost-sharing programmes, albeit with safeguards. The Gateway Paper regards efficient fund utilization a priority and lays stress on striking a balance between minimizing costs, controlling costs and using resources more efficiently and equitably--in other words, getting the best value for the money, on the one hand, and increasing the pool of available resources, on the other. Specific interventions such as the promotion of transparent financial administration, budgeting and cost

  3. Science Goals and Objectives for Canadian Robotic Exploration of the Moon Enabled by the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Bourassa, M.; Osinski, G. R.; Cross, M.; Hill, P.; King, D.; Morse, Z.; Pilles, E.; Tolometti, G.; Tornabene, L. L.; Zanetti, M.

    2018-02-01

    Canadian contributions to the science goals and objectives of a lunar precursor rover for HERACLES, an international mission concept, are discussed. Enabled by the Deep Space Gateway, this rover is a technical demonstrator for robotic sample return.

  4. From the Adam Smith Institute to the Zapatistas: An Internet Gateway to all Development Knowledge.

    ERIC Educational Resources Information Center

    Wilks, Alex

    2002-01-01

    Examines the World Bank Internet initiative, the Development Gateway. Describes the importance of the Bank as a knowledge bank and the threats posed by the Internet to its near monopoly of development thinking. Argues that the initiative reveals biases and misunderstandings in the World Bank's approach to knowledge for development. (CAJ)

  5. The New Gateway, an Old Paradox: Immigrants and Involuntary Americans in North Carolina History Textbooks

    ERIC Educational Resources Information Center

    Hilburn, Jeremy; Fitchett, Paul G.

    2012-01-01

    The authors conducted a content analysis of North Carolina history textbooks to explore how the definition of immigration has changed over the last century. They also examined how immigrant groups and involuntary Americans have been portrayed throughout the state's history. Findings suggest that as a burgeoning gateway state for immigrants, North…

  6. Using Collaborative Two-Stage Examinations to Address Test Anxiety in a Large Enrollment Gateway Course

    ERIC Educational Resources Information Center

    Fournier, Kimberly A.; Couret, Jannelle; Ramsay, Jason B.; Caulkins, Joshua L.

    2017-01-01

    Large enrollment foundational courses are perceived as "high stakes" because of their potential to act as barriers for progression to the next course or admittance to a program. The nature of gateway courses makes them ideal settings to explore the relationship between anxiety, pedagogical interventions, and student performance. Here,…

  7. The NC3Rs gateway: Accelerating scientific discoveries with new 3Rs models and technologies

    PubMed Central

    Percie du Sert, Nathalie; Robinson, Vicky

    2018-01-01

    This editorial introduces the NC3Rs gateway, which publishes articles and reviews on new models and technologies emerging from NC3Rs-funded research. The aim is to raise awareness about these approaches, increase confidence in their capability, and provide sufficient information to facilitate their uptake by others. PMID:29862024

  8. Virtual Labs (Science Gateways) as platforms for Free and Open Source Science

    NASA Astrophysics Data System (ADS)

    Lescinsky, David; Car, Nicholas; Fraser, Ryan; Friedrich, Carsten; Kemp, Carina; Squire, Geoffrey

    2016-04-01

    The Free and Open Source Software (FOSS) movement promotes community engagement in software development, as well as provides access to a range of sophisticated technologies that would be prohibitively expensive if obtained commercially. However, as geoinformatics and eResearch tools and services become more dispersed, it becomes more complicated to identify and interface between the many required components. Virtual Laboratories (VLs, also known as Science Gateways) simplify the management and coordination of these components by providing a platform linking many, if not all, of the steps in particular scientific processes. These enable scientists to focus on their science, rather than the underlying supporting technologies. We describe a modular, open source, VL infrastructure that can be reconfigured to create VLs for a wide range of disciplines. Development of this infrastructure has been led by CSIRO in collaboration with Geoscience Australia and the National Computational Infrastructure (NCI) with support from the National eResearch Collaboration Tools and Resources (NeCTAR) and the Australian National Data Service (ANDS). Initially, the infrastructure was developed to support the Virtual Geophysical Laboratory (VGL), and has subsequently been repurposed to create the Virtual Hazards Impact and Risk Laboratory (VHIRL) and the reconfigured Australian National Virtual Geophysics Laboratory (ANVGL). During each step of development, new capabilities and services have been added and/or enhanced. We plan on continuing to follow this model using a shared, community code base. The VL platform facilitates transparent and reproducible science by providing access to both the data and methodologies used during scientific investigations. This is further enhanced by the ability to set up and run investigations using computational resources accessed through the VL. Data is accessed using registries pointing to catalogues within public data repositories (notably including the

  9. A global map of travel time to cities to assess inequalities in accessibility in 2015

    NASA Astrophysics Data System (ADS)

    Weiss, D. J.; Nelson, A.; Gibson, H. S.; Temperley, W.; Peedell, S.; Lieber, A.; Hancher, M.; Poyart, E.; Belchior, S.; Fullman, N.; Mappin, B.; Dalrymple, U.; Rozier, J.; Lucas, T. C. D.; Howes, R. E.; Tusting, L. S.; Kang, S. Y.; Cameron, E.; Bisanzio, D.; Battle, K. E.; Bhatt, S.; Gething, P. W.

    2018-01-01

    The economic and man-made resources that sustain human wellbeing are not distributed evenly across the world, but are instead heavily concentrated in cities. Poor access to opportunities and services offered by urban centres (a function of distance, transport infrastructure, and the spatial distribution of cities) is a major barrier to improved livelihoods and overall development. Advancing accessibility worldwide underpins the equity agenda of ‘leaving no one behind’ established by the Sustainable Development Goals of the United Nations. This has renewed international efforts to accurately measure accessibility and generate a metric that can inform the design and implementation of development policies. The only previous attempt to reliably map accessibility worldwide, which was published nearly a decade ago, predated the baseline for the Sustainable Development Goals and excluded the recent expansion in infrastructure networks, particularly in lower-resource settings. In parallel, new data sources provided by Open Street Map and Google now capture transportation networks with unprecedented detail and precision. Here we develop and validate a map that quantifies travel time to cities for 2015 at a spatial resolution of approximately one by one kilometre by integrating ten global-scale surfaces that characterize factors affecting human movement rates and 13,840 high-density urban centres within an established geospatial-modelling framework. Our results highlight disparities in accessibility relative to wealth as 50.9% of individuals living in low-income settings (concentrated in sub-Saharan Africa) reside within an hour of a city compared to 90.7% of individuals in high-income settings. By further triangulating this map against socioeconomic datasets, we demonstrate how access to urban centres stratifies the economic, educational, and health status of humanity.

  10. A global map of travel time to cities to assess inequalities in accessibility in 2015.

    PubMed

    Weiss, D J; Nelson, A; Gibson, H S; Temperley, W; Peedell, S; Lieber, A; Hancher, M; Poyart, E; Belchior, S; Fullman, N; Mappin, B; Dalrymple, U; Rozier, J; Lucas, T C D; Howes, R E; Tusting, L S; Kang, S Y; Cameron, E; Bisanzio, D; Battle, K E; Bhatt, S; Gething, P W

    2018-01-18

    The economic and man-made resources that sustain human wellbeing are not distributed evenly across the world, but are instead heavily concentrated in cities. Poor access to opportunities and services offered by urban centres (a function of distance, transport infrastructure, and the spatial distribution of cities) is a major barrier to improved livelihoods and overall development. Advancing accessibility worldwide underpins the equity agenda of 'leaving no one behind' established by the Sustainable Development Goals of the United Nations. This has renewed international efforts to accurately measure accessibility and generate a metric that can inform the design and implementation of development policies. The only previous attempt to reliably map accessibility worldwide, which was published nearly a decade ago, predated the baseline for the Sustainable Development Goals and excluded the recent expansion in infrastructure networks, particularly in lower-resource settings. In parallel, new data sources provided by Open Street Map and Google now capture transportation networks with unprecedented detail and precision. Here we develop and validate a map that quantifies travel time to cities for 2015 at a spatial resolution of approximately one by one kilometre by integrating ten global-scale surfaces that characterize factors affecting human movement rates and 13,840 high-density urban centres within an established geospatial-modelling framework. Our results highlight disparities in accessibility relative to wealth as 50.9% of individuals living in low-income settings (concentrated in sub-Saharan Africa) reside within an hour of a city compared to 90.7% of individuals in high-income settings. By further triangulating this map against socioeconomic datasets, we demonstrate how access to urban centres stratifies the economic, educational, and health status of humanity.

  11. Recombinational Cloning Using Gateway and In-Fusion Cloning Schemes

    PubMed Central

    Throop, Andrea L.; LaBaer, Joshua

    2015-01-01

    The comprehensive study of protein structure and function, or proteomics, depends on the obtainability of full-length cDNAs in species-specific expression vectors and subsequent functional analysis of the expressed protein. Recombinational cloning is a universal cloning technique based on site-specific recombination that is independent of the insert DNA sequence of interest, which differentiates this method from the classical restriction enzyme-based cloning methods. Recombinational cloning enables rapid and efficient parallel transfer of DNA inserts into multiple expression systems. This unit summarizes strategies for generating expression-ready clones using the most popular recombinational cloning technologies, including the commercially available Gateway® (Life Technologies) and In-Fusion® (Clontech) cloning technologies. PMID:25827088

  12. The GPlates Portal: Cloud-Based Interactive 3D Visualization of Global Geophysical and Geological Data in a Web Browser.

    PubMed

    Müller, R Dietmar; Qin, Xiaodong; Sandwell, David T; Dutkiewicz, Adriana; Williams, Simon E; Flament, Nicolas; Maus, Stefan; Seton, Maria

    2016-01-01

    The pace of scientific discovery is being transformed by the availability of 'big data' and open access, open source software tools. These innovations open up new avenues for how scientists communicate and share data and ideas with each other and with the general public. Here, we describe our efforts to bring to life our studies of the Earth system, both at present day and through deep geological time. The GPlates Portal (portal.gplates.org) is a gateway to a series of virtual globes based on the Cesium Javascript library. The portal allows fast interactive visualization of global geophysical and geological data sets, draped over digital terrain models. The globes use WebGL for hardware-accelerated graphics and are cross-platform and cross-browser compatible with complete camera control. The globes include a visualization of a high-resolution global digital elevation model and the vertical gradient of the global gravity field, highlighting small-scale seafloor fabric such as abyssal hills, fracture zones and seamounts in unprecedented detail. The portal also features globes portraying seafloor geology and a global data set of marine magnetic anomaly identifications. The portal is specifically designed to visualize models of the Earth through geological time. These space-time globes include tectonic reconstructions of the Earth's gravity and magnetic fields, and several models of long-wavelength surface dynamic topography through time, including the interactive plotting of vertical motion histories at selected locations. The globes put the on-the-fly visualization of massive data sets at the fingertips of end-users to stimulate teaching and learning and novel avenues of inquiry.

  13. 76 FR 36154 - In the Matter of Certain Equipment for Communications Networks, Including Switches, Routers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... Communications Networks, Including Switches, Routers, Gateways, Bridges, Wireless Access Points, Cable Modems, IP... networks, including switches, routers, gateways, bridges, wireless access points, cable modems, IP phones... points, cable modems, IP phones, and products containing same that infringe one or more of claims 1, 5, 9...

  14. EPA Remote Sensing Information Gateway

    NASA Astrophysics Data System (ADS)

    Paulsen, H. K.; Szykman, J. J.; Plessel, T.; Freeman, M.; Dimmick, F.

    2009-12-01

    The Remote Sensing Information Gateway was developed by the U.S. Environmental Protection Agency (EPA) to assist researchers in easily obtaining and combining a variety of environmental datasets related to air quality research. Current datasets available include, but are not limited to surface PM2.5 and O3 data, satellite derived aerosol optical depth , and 3-dimensional output from U.S. EPA's Models 3/Community Multi-scale Air Quality (CMAQ) modeling system. The presentation will include a demonstration that illustrates several scenarios of how researchers use the tool to help them visualize and obtain data for their work; with a particular focus on episode analysis related to biomass burning impacts on air quality. The presentation will provide an overview on how RSIG works and how the code has been—and can be—adapted for other projects. One example is the Virtual Estuary, which focuses on automating the retrieval and pre-processing of a variety of data needed for estuarine research. RSIG’s source codes are freely available to researchers with permission from the EPA principal investigator, Dr. Jim Szykman. RSIG is available to the community and can be accessed online at http://www.epa.gov/rsig. Once the JAVA policy file is configured on your computer you can run the RSIG applet on your computer and connect to the RSIG server to visualize and retrieve available data sets. The applet allows the user to specify the temporal/spatial areas of interest, and the types of data to retrieve. The applet then communicates with RSIG subsetter codes located on the data owners’ remote servers; the subsetter codes assemble and transfer via ordinary Internet protocols only the specified data to the researcher’s computer. This is much faster than the usual method of transferring large files via FTP and greatly reduces network traffic. The RSIG applet then visualizes the transferred data on a latitude-longitude map, automatically locating the data in the correct

  15. Long-Range Plan for Gateway Technical Institute. 1982-1987: Serving Kenosha, Racine, and Walworth Counties.

    ERIC Educational Resources Information Center

    Stoehr, Keith W.; Covelli, Nicholas J.

    This report presents Gateway Technical Institute's long-range plan for 1982-1987. After prefatory material discussing financial and non-financial factors that may impinge on the plan, Chapter I outlines the socioeconomic situation in the three-county area of Wisconsin served by the college and introduces some of the critical issues that the…

  16. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2003-05-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 2F5, 2G12, abetimus sodium, ABI-007, adalimumab, adefovir dipivoxil, AE-941, alefacept, altropane, aminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, aminopterin, anakinra, aprinocarsen sodium, atazanavir, atlizumab, atomoxetine hydrochloride; B7-1 vaccine, bevacizumab, biricodar dicitrate, BMS-188667, brasofensine sulfate, bryostatin 1; cantuzumab mertansine, CHS-828, cinacalcet hydrochloride, cipamfylline, creatine, CVT-3146; darbepoetin alfa, DITPA, drotrecogin alfa (activated), duloxetine hydrochloride; edatrexate, efalizumab, ENMD-0997, epoetin, erlosamide, esomeprazole magnesium, etiprednol dicloacetate, etoricoxib, everolimus, ezetimibe; fampridine, fenretinide, FTY-720; IGF-I/IGFBP-3, IL-1 cytokine trap, ilodecakin, interferon beta, ISIS-104838, ISIS-2503, ISIS-5132, ivabradine hydrochloride; lafutidine, lanthanum carbonate, l-Arginine hydrochloride, LEA29Y, lerdelimumab, levetiracetam, levobupivacaine hydrochloride, levosimendan, lopinavir; melagatran, mibefradil hydrochloride, miglustat, morphine-6-glucuronide; nesiritide; omalizumab, omapatrilat; p24-VLP, parecoxib sodium, peginterferon alfa-2a, peginterferon alfa-2b, pegsunercept, pitavastatin calcium, plevitrexed, prasterone, pregabalin, PRO-2000, prucalopride; rapacuronium bromide, rebimastat, RGA-0853, rubitecan, ruboxistaurin mesilate hydrate, RWJ-67657; S-16020-2, sarizotan, SLV-306, stiripentol; TA-CIN, tenecteplase, teriparatide, tezacitabine, tipifarnib, trabectedin, troglitazone; valdecoxib, vardenafil; Z-338, ziconotide.

  17. Gateways to clinical trials.

    PubMed

    Bayés, M; Rabasseda, X; Prous, J R

    2005-12-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity. prous.com. This issue focuses on the following selection of drugs: 131I-chTNT; Abatacept, adalimumab, alemtuzumab, APC-8015, aprepitant, atazanavir sulfate, atomoxetine hydrochloride, azimilide hydrochloride; Bevacizumab, bortezomib, bosentan, buserelin; Caspofungin acetate, CC-4047, ChAGCD3, ciclesonide, clopidogrel, curcumin, Cypher; Dabigatran etexilate, dapoxetine hydrochloride, darbepoetin alfa, darusentan, denosumab, DMXB-Anabaseine, drospirenone, drospirenone/estradiol, duloxetine hydrochloride, dutasteride; Edodekin alfa, efaproxiral sodium, elaidic acid-cytarabine, erlotinib hydrochloride, ertapenem sodium, escitalopram oxalate, eszopiclone, etonogestrel/testosterone decanoate, exenatide; Fulvestrant; Gefitinib, glycine, GVS-111; Homoharringtonine; ICC-1132, imatinib mesylate, iodine (I131) tositumomab, i.v. gamma-globulin; Levetiracetam, levocetirizine, lintuzumab, liposomal nystatin, lumiracoxib, lurtotecan; Manitimus, mapatumumab, melatonin, micafungin sodium, mycophenolic acid sodium salt; Oblimersen sodium, OGX-011, olmesartan medoxomil, omalizumab, omapatrilat, oral insulin; Parathyroid hormone (human recombinant), pasireotide, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b/ribavirin, phVEGF-A165, pimecrolimus, pitavastatin calcium, plerixafor hydrochloride, posaconazole, pramlintide acetate, prasterone, pregabalin, PT-141; Quercetin; Ranolazine, rosuvastatin calcium, rubitecan, rupatadine fumarate; Sardomozide, sunitinib malate; Tadalafil, talactoferrin alfa, tegaserod maleate, telithromycin, testosterone transdermal patch, TH-9507, tigecycline, tiotropium bromide, tipifarnib, tocilizumab, treprostinil sodium; Valdecoxib, vandetanib

  18. Gateways to Clinical Trials.

    PubMed

    Bayés, M; Rabasseda, X; Prous, J R

    2002-09-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: Adalimumab, aeroDose insulin inhaler, agomelatine, alendronic acid sodium salt, aliskiren fumarate, alteplase, amlodipine, aspirin, atazanavir; Bacillus Calmette-Guérin, basiliximab, BQ-788, bupropion hydrochloride; Cabergoline, caffeine citrate, carbamazepine, carvedilol, celecoxib, cyclosporine, clopidogrel hydrogensulfate, colestyramine; Dexamethasone, diclofenac sodium, digoxin, dipyridamole, docetaxel, dutasteride; Eletriptan, enfuvirtidie, eplerenone, ergotamine tartrate, esomeprazole magnesium, estramustine phosphate sodium; Finasteride, fluticasone propionate, fosinopril sodium; Ganciclovir, GBE-761-ONC, glatiramer acetate, gliclazide, granulocyte-CSF; Heparin sodium, human isophane insulin (pyr), Hydrochlorothiazide; Ibuprofen, inhaled insulin, interferon alfa, interferon beta-1a; Laminvudine, lansoprazole, lisinopril, lonafarnib, losartan potassium, lumiracoxib; MAb G250, meloxicam methotrexate, methylprednisolone aceponate, mitomycin, mycophenolate mofetil; Naproxen sodium, natalizumab, nelfinavir mesilate, nemifitide ditriflutate, nimesulide; Omalizumab, omapatrilat, omeprazole, oxybutynin chloride; Pantoprazole sodium, paracetamol, paroxetine, pentoxifylline, pergolide mesylate, permixon, phVEGF-A165, pramipexole hydrochloride, prasterone, prednisone, probucol, propiverine hydrochloride; Rabeprazole sodium, resiniferatoxin, risedronate sodium, risperidone, rofecoxib rosiglitazone maleate, ruboxistaurin mesilate hydrate; Selegiline transdermal system, sertraline, sildenafil citrate, streptokinase; Tadalafil, tamsulosin hydrochloride, technosphere/Insulin, tegaserod maleate, tenofovir disoproxil

  19. Interoperable Data Access Services for NOAA IOOS

    NASA Astrophysics Data System (ADS)

    de La Beaujardiere, J.

    2008-12-01

    The Integrated Ocean Observing System (IOOS) is intended to enhance our ability to collect, deliver, and use ocean information. The goal is to support research and decision-making by providing data on our open oceans, coastal waters, and Great Lakes in the formats, rates, and scales required by scientists, managers, businesses, governments, and the public. The US National Oceanic and Atmospheric Administration (NOAA) is the lead agency for IOOS. NOAA's IOOS office supports the development of regional coastal observing capability and promotes data management efforts to increase data accessibility. Geospatial web services have been established at NOAA data providers including the National Data Buoy Center (NDBC), the Center for Operational Oceanographic Products and Services (CO-OPS), and CoastWatch, and at regional data provider sites. Services established include Open-source Project for a Network Data Access Protocol (OpenDAP), Open Geospatial Consortium (OGC) Sensor Observation Service (SOS), and OGC Web Coverage Service (WCS). These services provide integrated access to data holdings that have been aggregated at each center from multiple sources. We wish to collaborate with other groups to improve our service offerings to maximize interoperability and enhance cross-provider data integration, and to share common service components such as registries, catalogs, data conversion, and gateways. This paper will discuss the current status of NOAA's IOOS efforts and possible next steps.

  20. Space Biology Model Organism Research on the Deep Space Gateway to Pioneer Discovery and Advance Human Space Exploration

    NASA Astrophysics Data System (ADS)

    Sato, K. Y.; Tomko, D. L.; Levine, H. G.; Quincy, C. D.; Rayl, N. A.; Sowa, M. B.; Taylor, E. M.; Sun, S. C.; Kundrot, C. E.

    2018-02-01

    Model organisms are foundational for conducting physiological and systems biology research to define how life responds to the deep space environment. The organisms, areas of research, and Deep Space Gateway capabilities needed will be presented.

  1. The Divine Dreams of a Sample of South African Children: The Gateway to Their Spirituality

    ERIC Educational Resources Information Center

    Potgieter, Ferdinand J.; van der Walt, Johannes L.; Wolhuter, Charl C.

    2009-01-01

    As part of a research project on religion, spirituality and education, the authors attended to the role that children's divine dreams could play in religious education (RE). They contend that such dreams can indeed be used by RE teachers as the gateway to understanding the spirituality of their learners. They defend their claim by firstly…

  2. Improving Access to Essential Medicines: How Health Concerns can be Prioritised in the Global Governance System

    PubMed Central

    Sridhar, Devi

    2008-01-01

    This paper discusses the politics of access to essential medicines and identifies ‘space’ in the current system where health concerns can be strengthened relative to trade. This issue is addressed from a global governance perspective focusing on the main actors who can have the greatest impact. These include developing country coalitions and citizens in developed countries though participation in civil society organisations. These actors have combined forces to tackle this issue successfully, resulting in the 2001 Doha Declaration on Public Health. The collaboration has been so powerful due to the assistance of the media as well as the decision to compromise with pharmaceutical companies and their host countries. To improve access to essential medicines, six C's are needed: coalitions, civil society, citizenship, compromise, communication and collaboration. PMID:19461853

  3. 78 FR 79707 - Notice of Public Meeting, Gateway West Project Subcommittee of the Boise District Resource...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ... Resource Advisory Council on matters of planning and management of the Gateway West Project (sections 8 and... Interior, through the BLM, on a variety of planning and management issues associated with public land... a telecommunications device for the deaf (TDD) may call the Federal Information Relay Service (FIRS...

  4. Gateways to the Internet: A Host of Companies Want To Be Your District's Customized Education Portal.

    ERIC Educational Resources Information Center

    Bushweller, Kevin

    2000-01-01

    In the ephemeral dot.com economy, numerous education portals (search engines) are emerging just as unsuccessful ones are terminating or trimming services. Ideally, portals offer an online school/home gateway and provide tailored content for parents, students, and teachers. However, quality, equity, reliability, and commercialism issues abound.…

  5. Disaster Response Tools for Decision Support and Data Discovery - E-DECIDER and GeoGateway

    NASA Astrophysics Data System (ADS)

    Glasscoe, M. T.; Donnellan, A.; Parker, J. W.; Granat, R. A.; Lyzenga, G. A.; Pierce, M. E.; Wang, J.; Grant Ludwig, L.; Eguchi, R. T.; Huyck, C. K.; Hu, Z.; Chen, Z.; Yoder, M. R.; Rundle, J. B.; Rosinski, A.

    2015-12-01

    Providing actionable data for situational awareness following an earthquake or other disaster is critical to decision makers in order to improve their ability to anticipate requirements and provide appropriate resources for response. E-DECIDER (Emergency Data Enhanced Cyber-Infrastructure for Disaster Evaluation and Response) is a decision support system producing remote sensing and geophysical modeling products that are relevant to the emergency preparedness and response communities and serves as a gateway to enable the delivery of actionable information to these communities. GeoGateway is a data product search and analysis gateway for scientific discovery, field use, and disaster response focused on NASA UAVSAR and GPS data that integrates with fault data, seismicity and models. Key information on the nature, magnitude and scope of damage, or Essential Elements of Information (EEI), necessary to achieve situational awareness are often generated from a wide array of organizations and disciplines, using any number of geospatial and non-geospatial technologies. We have worked in partnership with the California Earthquake Clearinghouse to develop actionable data products for use in their response efforts, particularly in regularly scheduled, statewide exercises like the recent May 2015 Capstone/SoCal NLE/Ardent Sentry Exercises and in the August 2014 South Napa earthquake activation. We also provided a number of products, services, and consultation to the NASA agency-wide response to the April 2015 Gorkha, Nepal earthquake. We will present perspectives on developing tools for decision support and data discovery in partnership with the Clearinghouse and for the Nepal earthquake. Products delivered included map layers as part of the common operational data plan for the Clearinghouse, delivered through XchangeCore Web Service Data Orchestration, enabling users to create merged datasets from multiple providers. For the Nepal response effort, products included models

  6. GATEWAY Report Brief: Evaluating OLED Lighting in the Accounting Office of DeJoy, Knauf & Blood LLP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Summary of GATEWAY report evaluating a new lighting system, at the offices of the accounting firm of DeJoy, Knauf & Blood, LLP in Rochester, NY, that incorporates a number of different OLED luminaires. Evaluation of the OLED products included efficacy performance, field measurements of panel color, flicker measurements, and staff feedback.

  7. A Gateway to Health Careers for Urban High School Students: Collaborative Front-Line and Allied Workforce Development Program among High Schools, Public Hospitals and Public Colleges. Program Results Report

    ERIC Educational Resources Information Center

    Jablow, Paul

    2012-01-01

    From 2005 to 2011, the Gateway Institute for Pre-College Education partnered with three public entities in New York City--the Department of Education, the City University of New York and the Health and Hospitals Corporation--to introduce, educate, and prepare urban high school students for careers in the health professions. Gateway was launched in…

  8. A Global Assessment of Access to and Use of Medical Information: The State of Evidence-Based Surgery.

    PubMed

    LaGrone, Lacey N; Fuhs, Amy K; Egoavil, Eduardo Huaman; Langdale, Lorrie A; Fuangworawong, Phupit; Hamasaki, Jose Luis; Gyedu, Adam; Mock, Charles N

    2018-02-01

    We aimed to assess surgeons' access to and use of medical information, as well as their training and perceptions about evidence-based medicine (EBM), in order to identify priority areas for improvement. An anonymous survey conducted among surgeons from the USA, Ghana, Peru, and Thailand examined access to, and use and perception of, medical literature. Of 307 participants, 98% reported access to "OK" or "good" internet. Fifty-one percent reported that language was a barrier to accessing needed medical information; most frequently in Peru (73%) and Thailand (64%). Access to priced full-text journals was poorest in Peru, where 54% lacked access, followed by Ghana (42%) and Thailand (32%). US respondents scored highest on the EBM knowledge test (1.4, SD 0.8), followed by Thailand (1.3, SD 0.9), Ghana (1.1, SD 0.8), and Peru (0.9, SD 0.8) (p < 0.001). Adjusted analysis revealed Ghanaians and Peruvians spent 5% and 1% more on medical information, respectively, relative to country income, than persons from other countries (p < 0.01). After adjustment, employment in a large and/or urban hospital and history of EBM training were associated with better EBM test scores, while middle-income origin and public hospital employment were associated with worse scores (p < 0.05). Language, access to priced full-text journals, and training are significant barriers to surgeons' practice of EBM globally. The way forward involves collaboration among surgical societies, publishers, hospital employers, and international policymakers in providing surgeons from all country income levels with the access and training necessary to interpret and apply medical information.

  9. MO-FG-BRB-02: Uniform Access to Radiation Therapy by 2035: Global Task Force on Radiotherapy for Cancer Control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jaffray, D.

    The global burden of cancer is growing rapidly with an estimated 15 million new cases per year worldwide in 2015, growing to 19 million by 2025 and 24 million by 2035. The largest component of this growth will occur in low-to-middle income countries (LMICs). About half of these cases will require radiation treatment. The gap for available cancer treatment, including radiation therapy, between high-income countries (HICs) and LMICs is enormous. Accurate data and quantitative models to project the needs and the benefits of cancer treatment are a critical first step in closing the large cancer divide between LMICs and HICs.more » In this context, the Union for International Cancer Control (UICC) has developed a Global Task Force on Radiotherapy for Cancer Control (GTFRCC) with a charge to answer the question as to what it will take to close the gap between what exists today and reasonable access to radiation therapy globally by 2035 and what the potential clinical and economic benefits are for doing this. The Task Force has determined the projections of cancer incidence and the infrastructure required to provide access to radiation therapy globally. Furthermore it has shown that appropriate investment not only yields improved clinical outcomes for millions of patients but that it also provides an overall economic gain throughout all the income settings where this investment is made. This symposium will summarize the facets associated with this global cancer challenge by reviewing the cancer burden, looking at the requirements for radiation therapy, reviewing the benefits of providing such therapy both from a clinical and economic perspective and finally by looking at what approaches can be used to aid in the alleviation of this global cancer challenge. The speakers are world renowned experts in global public health issues (R. Atun), medical physics (D. Jaffray) and radiation oncology (N. Coleman). Learning Objectives: To describe the global cancer challenge and the

  10. Amplified North Atlantic Warming in the Late Pliocene by Changes in Arctic Gateways

    NASA Astrophysics Data System (ADS)

    Otto-Bliesner, B. L.; Jahn, A.; Feng, R.; Brady, E. C.; Hu, A.; Lofverstrom, M.

    2017-12-01

    Reconstructions of the late Pliocene (mid-Piacenzian, 3.3 - 3.0 million years ago) sea surface temperature (SST) find much warmer conditions in the North Atlantic than modern. The much warmer SSTs, up to 8.8°C from sites with good dating and replicates from several different types of proxies, have been difficult for climate models to reproduce. Even with the slow feedbacks of a reduced Greenland ice sheet and expansion of boreal forests to the Arctic Ocean over Canada and Eurasia, models cannot warm the North Atlantic sufficiently to match the reconstructed SSTs. An enhancement of the Atlantic Meridional Overturning Circulation (AMOC) during the late Pliocene, proposed as a possible mechanism based on ocean core records of δ13C, also is not present in the model simulations. Here, we present CESM simulations using a new reconstruction of late Pliocene paleogeography that has the Bering Strait (BS) and Canadian Arctic Archipelago (CAA) Straits closed. We find that the closure of these small Arctic gateways strengthens the AMOC, by inhibiting freshwater (FW) transport from the Pacific to the Arctic Ocean and from the Arctic Ocean to the Labrador Sea, leading to warmer sea surface temperatures in the North Atlantic. The cutoff of the short export route through the CAA results in a more saline Labrador and south Greenland Sea with increased deep convection. At the same time, as all FW now leaves the Arctic east of Greenland, there is a freshening of and decreased deepwater formation in the Norwegian Sea. Overall, the AMOC strengthens. This past time period has implications for a future Earth under more responsible scenarios of emissions. Late Pliocene atmospheric carbon dioxide concentrations are estimated to have ranged between 350 and 450 ppmv and the paleogeography is relatively similar to modern. Our study indicates that the state of the Arctic gateways may influence the sensitivity of the North Atlantic climate in complex ways, and better understanding of the

  11. Gateways to clinical trials.

    PubMed

    Bayés, M; Rabasseda, X; Prous, J R

    2007-12-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Intergrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 249553, 2-Methoxyestradiol; Abatacept, Adalimumab, Adefovir dipivoxil, Agalsidase beta, Albinterferon alfa-2b, Aliskiren fumarate, Alovudine, Amdoxovir, Amlodipine besylate/atorvastatin calcium, Amrubicin hydrochloride, Anakinra, AQ-13, Aripiprazole, AS-1404, Asoprisnil, Atacicept, Atrasentan; Belimumab, Bevacizumab, Bortezomib, Bosentan, Botulinum toxin type B, Brivaracetam; Catumaxomab, Cediranib, Cetuximab, cG250, Ciclesonide, Cinacalcet hydrochloride, Curcumin, Cypher; Darbepoetin alfa, Denosumab, Dihydrexidine; Eicosapentaenoic acid/docosahexaenoic acid, Entecavir, Erlotinib hydrochloride, Escitalopram oxalate, Etoricoxib, Everolimus, Ezetimibe; Febuxostat, Fenspiride hydrochloride, Fondaparinux sodium; Gefitinib, Ghrelin (human), GSK-1562902A; HSV-tk/GCV; Iclaprim, Imatinib mesylate, Imexon, Indacaterol, Insulinotropin, ISIS-112989; L-Alanosine, Lapatinib ditosylate, Laropiprant; Methoxy polyethylene glycol-epoetin-beta, Mipomersen sodium, Motexafin gadolinium; Natalizumab, Nimotuzumab; OSC, Ozarelix; PACAP-38, Paclitaxel nanoparticles, Parathyroid Hormone-Related Protein-(1-36), Pasireotide, Pegfilgrastim, Peginterferon alfa-2a, Peginterferon alfa-2b, Pemetrexed disodium, Pertuzumab, Picoplatin, Pimecrolimus, Pitavastatin calcium, Plitidepsin; Ranelic acid distrontium salt, Ranolazine, Recombinant human relaxin H2, Regadenoson, RFB4(dsFv)-PE38, RO-3300074, Rosuvastatin calcium; SIR-Spheres, Solifenacin succinate, Sorafenib, Sunitinib malate; Tadalafil, Talabostat, Taribavirin hydrochloride, Taxus, Temsirolimus, Teriparatide, Tiotropium bromide, Tipifarnib, Tirapazamine, Tocilizumab; UCN-01, Ularitide

  12. EAARL topography: Gateway National Recreation Area

    USGS Publications Warehouse

    Brock, John C.; Wright, C. Wayne; Patterson, Matt; Nayegandhi, Amar; Patterson, Judd

    2007-01-01

    This Web site contains Lidar-derived topography (bare earth) maps and GIS files for the Sandy Hook Unit within Gateway National Recreation Area in New Jersey. These Lidar-derived topography maps were produced as a collaborative effort between the U.S. Geological Survey (USGS) Coastal and Marine Geology Program, FISC St. Petersburg, the National Park Service (NPS) South Florida/Caribbean Network Inventory and Monitoring Program, and the National Aeronautics and Space Administration (NASA) Wallops Flight Facility. One objective of this research is to create techniques to survey coral reefs and barrier islands for the purposes of geomorphic change studies, habitat mapping, ecological monitoring, change detection, and event assessment. As part of this project, data from an innovative instrument under development at the NASA Wallops Flight Facility, the NASA Experimental Airborne Advanced Research Lidar (EAARL) are being used. This sensor has the potential to make significant contributions in this realm for measuring subaerial and submarine topography wthin cross-environment surveys. High spectral resolution, water-column correction, and low costs were found to be key factors in providing accurate and affordable imagery to costal resource managers.

  13. A review of global access to emergency contraception.

    PubMed

    Westley, Elizabeth; Kapp, Nathalie; Palermo, Tia; Bleck, Jennifer

    2013-10-01

    Emergency contraception has been known for several decades, and dedicated products have been on the market for close to 20 years. Yet it is unclear whether women, particularly in low-resource countries, have access to this important second-chance method of contraception. To review relevant policies, regulations, and other factors related to access to emergency contraception worldwide. A wide range of gray literature was reviewed, several specific studies were commissioned, and a number of online databases were searched. Several positive policies and regulations are in place: emergency contraception products are registered in the majority of countries around the world, listed in many countries' essential medicines lists, included in widely used guidance, and supported by most donors. Yet analysis of demographic data shows that the majority of women in low-income countries have never heard of emergency contraception, and surveys find that many providers have negative attitudes toward providing emergency contraception. Despite more than a decade of concerted international and country-level efforts to ensure that women have access to emergency contraception, accessibility remains limited. © 2013.

  14. 78 FR 39386 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... data (``Logical Ports''). Each Logical Port is assigned an access gateway that performs order... Change to Offer and Establish Fees for a New Exchange Service, EdgeRisk Gateways June 25, 2013. Pursuant... Exchange has designated the proposed rule change as it pertains to the fees for EdgeRisk Gateway SM (the...

  15. 78 FR 39395 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... data (``Logical Ports''). Each Logical Port is assigned an access gateway that performs order... Change to Offer and Establish Fees for a New Exchange Service, EdgeRisk Gateways June 25, 2013. Pursuant... Exchange has designated the proposed rule change as it pertains to the fees for EdgeRisk Gateway\\SM\\ (the...

  16. Global Climate Change for Kids: Making Difficult Ideas Accessible and Exciting

    NASA Astrophysics Data System (ADS)

    Fisher, D. K.; Leon, N.; Greene, M. P.

    2009-12-01

    NASA has recently launched its Global Climate Change web site (http://climate.nasa.gov), and it has been very well received. It has now also launched in preliminary form an associated site for children and educators, with a plan for completion in the near future. The goals of the NASA Global Climate Change Education site are: To increase awareness and understanding of climate change science in upper-elementary and middle-school students, reinforcing and building upon basic concepts introduced in the formal science education curriculum for these grades; To present, insofar as possible, a holistic picture of climate change science and current evidence of climate change, describing Earth as a system of interconnected processes; To be entertaining and motivating; To be clear and easy to understand; To be easy to navigate; To address multiple learning styles; To describe and promote "green" careers; To increase awareness of NASA's contributions to climate change science; To provide valuable resources for educators; To be compliant with Section 508 of the Americans with Disabilities Act. The site incorporates research findings not only on climate change, but also on effective web design for children. It is envisioned that most of the content of the site will ultimately be presented in multimedia forms. These will include illustrated and narrated "slide shows," animated expositions, interactive concept-rich games and demonstrations, videos, animated fictionalized stories, and printable picture galleries. In recognition of the attention span of the audience, content is presented in short, modular form, with a suggested, but not mandatory order of access. Empathetic animal and human cartoon personalities are used to explain concepts and tell stories. Expository, fiction, game, video, text, and image modules are interlinked for reinforcement of similar ideas. NASA's Global Climate Change Education web site addresses the vital need to impart and emphasize Earth system science

  17. Amplified Late Pliocene terrestrial warmth in northern high latitudes from greater radiative forcing and closed Arctic Ocean gateways

    NASA Astrophysics Data System (ADS)

    Feng, Ran; Otto-Bliesner, Bette L.; Fletcher, Tamara L.; Tabor, Clay R.; Ballantyne, Ashley P.; Brady, Esther C.

    2017-05-01

    Proxy reconstructions of the mid-Piacenzian warm period (mPWP, between 3.264 and 3.025 Ma) suggest terrestrial temperatures were much warmer in the northern high latitudes (55°-90°N, referred to as NHL) than present-day. Climate models participating in the Pliocene Model Intercomparison Project Phase 1 (PlioMIP1) tend to underestimate this warmth. For instance, the underestimate is ∼10 °C on average across NHL and up to 17 °C in the Canadian Arctic region in the Community Climate System Model version 4 (CCSM4). Here, we explore potential mPWP climate forcings that might contribute to this mPWP mismatch. We carry out seven experiments to assess terrestrial temperature responses to Pliocene Arctic gateway closure, variations in CO2 level, and orbital forcing at millennial time scale. To better compare the full range of simulated terrestrial temperatures with sparse proxy data, we introduce a pattern recognition technique that simplifies the model surface temperatures to a few representative patterns that can be validate with the limited terrestrial proxy data. The pattern recognition technique reveals two prominent features of simulated Pliocene surface temperature responses. First, distinctive patterns of amplified warming occur in the NHL, which can be explained by lowered surface elevation of Greenland, pattern and amount of Arctic sea ice loss, and changing strength of Atlantic meridional overturning circulation. Second, patterns of surface temperature response are similar among experiments with different forcing mechanisms. This similarity is due to strong feedbacks from responses in surface albedo and troposphere water vapor content to sea ice changes, which overwhelm distinctions in forcings from changes in insolation, CO2 forcing, and Arctic gateway closure. By comparing CCSM4 simulations with proxy records, we demonstrate that both model and proxy records show similar patterns of mPWP NHL terrestrial warmth, but the model underestimates the magnitude

  18. Breaking open the set top box

    NASA Astrophysics Data System (ADS)

    Banks, David; Wiley, Anthony; Catania, Nicolas; Coles, Alastair N.; Smith, Duncan; Baynham, Simon; Deliot, Eric; Chidzey, Rod

    1998-02-01

    In this paper we describe the work being done at HP Labs Bristol in the area of home networks and gateways. This work is based on the idea of breaking open the set top box by physically separating the access network specific functions from the application specific functions. The access network specific functions reside in an access network gateway that can be shared by many end user devices. The first section of the paper present the philosophy behind this approach. The end user devices and the access network gateways must be interconnected by a high bandwidth network which can offer a bounded delay service for delay sensitive traffic. We are advocating the use of IEEE 1394 for this network, and the next section of the paper gives a brief introduction to this technology. We then describe a prototype digital video broadcasting satellite compliant gateway that we have built. This gateway could be used, for example, by a PC for receiving a data service or by a digital TV for receiving an MPEG-2 video service. A control architecture is the presented which uses a PC application to provide a web based user interface to the system. Finally, we provide details of our work on extending the reach of IEEE 1394 and its standardization status.

  19. Pliocene oceanic seaways and global climate.

    PubMed

    Karas, Cyrus; Nürnberg, Dirk; Bahr, André; Groeneveld, Jeroen; Herrle, Jens O; Tiedemann, Ralf; deMenocal, Peter B

    2017-01-05

    Tectonically induced changes in oceanic seaways had profound effects on global and regional climate during the Late Neogene. The constriction of the Central American Seaway reached a critical threshold during the early Pliocene ~4.8-4 million years (Ma) ago. Model simulations indicate the strengthening of the Atlantic Meridional Overturning Circulation (AMOC) with a signature warming response in the Northern Hemisphere and cooling in the Southern Hemisphere. Subsequently, between ~4-3 Ma, the constriction of the Indonesian Seaway impacted regional climate and might have accelerated the Northern Hemisphere Glaciation. We here present Pliocene Atlantic interhemispheric sea surface temperature and salinity gradients (deduced from foraminiferal Mg/Ca and stable oxygen isotopes, δ 18 O) in combination with a recently published benthic stable carbon isotope (δ 13 C) record from the southernmost extent of North Atlantic Deep Water to reconstruct gateway-related changes in the AMOC mode. After an early reduction of the AMOC at ~5.3 Ma, we show in agreement with model simulations of the impacts of Central American Seaway closure a strengthened AMOC with a global climate signature. During ~3.8-3 Ma, we suggest a weakening of the AMOC in line with the global cooling trend, with possible contributions from the constriction of the Indonesian Seaway.

  20. On the capability of smartphones to perform as communication gateways in medical wireless personal area networks.

    PubMed

    Morón, María José; Luque, Rafael; Casilari, Eduardo

    2014-01-02

    This paper evaluates and characterizes the technical performance of medical wireless personal area networks (WPANs) that are based on smartphones. For this purpose,a prototype of a health telemonitoring system is presented. The prototype incorporates a commercial Android smartphone, which acts as a relay point, or "gateway", between a set of wireless medical sensors and a data server. Additionally, the paper investigates if the conventional capabilities of current commercial smartphones can be affected by their use as gateways or "Holters" in health monitoring applications. Specifically, the profiling has focused on the CPU and power consumption of the mobile devices. These metrics have been measured under several test conditions modifying the smartphone model, the type of sensors connected to the WPAN, the employed Bluetooth profile (SPP (serial port profile) orHDP (health device profile)), the use of other peripherals, such as a GPS receiver, the impact of the use of the Wi-Fi interface or the employed method to encode and forward the data that are collected from the sensors.

  1. Remote In-Space Manufacturing Applied with the Science of Interplanetary Supply Chain Modeling for Deep Space Gateway Application

    NASA Astrophysics Data System (ADS)

    Galluzzi, M. C.

    2018-02-01

    Three goals can be achieved by 2030: 1. NASA will have the capability for remote on-demand 3d printing of critical hardware using regolith material as feedstock, 2. Logistics footprint reduced by 35%, 3. Deep Space Gateway will become 75% self-sustaining.

  2. 78 FR 70959 - Gateway West Project Subcommittee of the Resource Advisory Council to the Boise District; Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... advises the Boise District Resource Advisory Council on matters of planning and management of the Gateway... the Interior, through the BLM, on a variety of planning and management issues associated with public.... Persons who use a telecommunications device for the deaf (TDD) may call the Federal Information Relay...

  3. The GPlates Portal: Cloud-Based Interactive 3D Visualization of Global Geophysical and Geological Data in a Web Browser

    PubMed Central

    Müller, R. Dietmar; Qin, Xiaodong; Sandwell, David T.; Dutkiewicz, Adriana; Williams, Simon E.; Flament, Nicolas; Maus, Stefan; Seton, Maria

    2016-01-01

    The pace of scientific discovery is being transformed by the availability of ‘big data’ and open access, open source software tools. These innovations open up new avenues for how scientists communicate and share data and ideas with each other and with the general public. Here, we describe our efforts to bring to life our studies of the Earth system, both at present day and through deep geological time. The GPlates Portal (portal.gplates.org) is a gateway to a series of virtual globes based on the Cesium Javascript library. The portal allows fast interactive visualization of global geophysical and geological data sets, draped over digital terrain models. The globes use WebGL for hardware-accelerated graphics and are cross-platform and cross-browser compatible with complete camera control. The globes include a visualization of a high-resolution global digital elevation model and the vertical gradient of the global gravity field, highlighting small-scale seafloor fabric such as abyssal hills, fracture zones and seamounts in unprecedented detail. The portal also features globes portraying seafloor geology and a global data set of marine magnetic anomaly identifications. The portal is specifically designed to visualize models of the Earth through geological time. These space-time globes include tectonic reconstructions of the Earth’s gravity and magnetic fields, and several models of long-wavelength surface dynamic topography through time, including the interactive plotting of vertical motion histories at selected locations. The globes put the on-the-fly visualization of massive data sets at the fingertips of end-users to stimulate teaching and learning and novel avenues of inquiry. PMID:26960151

  4. Global Scenarios of Air Pollution until 2030: Combining Air Quality, Climate Change and Energy Access Policies

    NASA Astrophysics Data System (ADS)

    Rao, S.; Dentener, F. J.; Klimont, Z.; Riahi, K.

    2011-12-01

    Outdoor air pollution is increasingly recognized as a significant contributor to global health outcomes. This has led to the implementation of a number of air quality policies worldwide, with total air pollution control costs in 2005 estimated at US$195 billion. More than 80% of the world's population is still found to be exposed to PM2.5 concentrations exceeding WHO air quality guidelines and health impacts resulting from these exposures estimated at around 2-5% of the global disease burden. Key questions to answer are 1) How will pollutant emissions evolve in the future given developments in the energy system and how will energy and environmental policies influence such emission trends. 2) What implications will this have for resulting exposures and related health outcomes. In order to answer these questions, varying levels of stringency of air quality legislation are analyzed in combination with policies on universal access to clean cooking fuels and limiting global temperature change to 2°C in 2100. Bottom-up methodologies using energy emissions modeling are used to derive sector-based pollutant emission trajectories until 2030. Emissions are spatially downscaled and used in combination with a global transport chemistry model to derive ambient concentrations of PM2.5. Health impacts of these exposures are further estimated consistent with WHO data and methodology. The results indicate that currently planned air quality legislation combined with rising energy demand will be insufficient in controlling future emissions growth in developing countries. In order to achieve significant reductions in pollutant emissions of the order of more than 50% from 2005 levels and reduce exposures to levels consistent with WHO standards, it will be necessary to increase the stringency of such legislations and combine them with policies on energy access and climate change. Combined policies also result in reductions in air pollution control costs as compared to those associated

  5. Guiding Early and Often: Using Curricular and Learning Analytics to Shape Teaching, Learning, and Student Success in Gateway Courses

    ERIC Educational Resources Information Center

    Pistilli, Matthew D.; Heileman, Gregory L.

    2017-01-01

    This chapter provides information on how the promise of analytics can be realized in gateway courses through a combination of good data science and the thoughtful application of outcomes to teaching and learning improvement efforts--especially with and among instructors.

  6. Linking research to global health equity: the contribution of product development partnerships to access to medicines and research capacity building.

    PubMed

    Pratt, Bridget; Loff, Bebe

    2013-11-01

    Certain product development partnerships (PDPs) recognize that to promote the reduction of global health disparities they must create access to their products and strengthen research capacity in developing countries. We evaluated the contribution of 3 PDPs--Medicines for Malaria Venture, Drugs for Neglected Diseases Initiative, and Institute for One World Health--according to Frost and Reich's access framework. We also evaluated PDPs' capacity building in low- and middle-income countries at the individual, institutional, and system levels. We found that these PDPs advance public health by ensuring their products' registration, distribution, and adoption into national treatment policies in disease-endemic countries. Nonetheless, ensuring broad, equitable access for these populations--high distribution coverage; affordability, particularly for the poor; and adoption at provider and end-user levels--remains a challenge.

  7. Functional Adult Literacy: An Alternative Gateway to Grassroots Women's Improved Income Generation in Lango Subregion, Northern Uganda

    ERIC Educational Resources Information Center

    Akello, Judith Abal; Lutwama-Rukundo, Evelyn; Musiimenta, Peace

    2017-01-01

    This article presents findings of study on women's experiences of Functional Adult Literacy (FAL) as a gateway to their financial progress and welfare in Lango region, Northern Uganda. The qualitative study of 45 participants aimed at examining women's live changes resulting from using their acquired FAL knowledge and skills to participate in…

  8. Network gateway security method for enterprise Grid: a literature review

    NASA Astrophysics Data System (ADS)

    Sujarwo, A.; Tan, J.

    2017-03-01

    The computational Grid has brought big computational resources closer to scientists. It enables people to do a large computational job anytime and anywhere without any physical border anymore. However, the massive and spread of computer participants either as user or computational provider arise problems in security. The challenge is on how the security system, especially the one which filters data in the gateway could works in flexibility depends on the registered Grid participants. This paper surveys what people have done to approach this challenge, in order to find the better and new method for enterprise Grid. The findings of this paper is the dynamically controlled enterprise firewall to secure the Grid resources from unwanted connections with a new firewall controlling method and components.

  9. Global cancer control: responding to the growing burden, rising costs and inequalities in access

    PubMed Central

    Braga, Sofia; Bystricky, Branislav; Qvortrup, Camilla; Criscitiello, Carmen; Esin, Ece; Sonke, Gabe S; Martínez, Guillem Argilés; Frenel, Jean-Sebastian; Karamouzis, Michalis; Strijbos, Michiel; Yazici, Ozan; Bossi, Paolo; Banerjee, Susana; Troiani, Teresa; Eniu, Alexandru; Ciardiello, Fortunato; Tabernero, Josep; Zielinski, Christoph C; Casali, Paolo G; Cardoso, Fatima; Douillard, Jean-Yves; McGregor, Keith; Bricalli, Gracemarie; Vyas, Malvika; Ilbawi, André

    2018-01-01

    The cancer burden is rising globally, exerting significant strain on populations and health systems at all income levels. In May 2017, world governments made a commitment to further invest in cancer control as a public health priority, passing the World Health Assembly Resolution 70.12 on cancer prevention and control within an integrated approach. In this manuscript, the 2016 European Society for Medical Oncology Leadership Generation Programme participants propose a strategic framework that is in line with the 2017 WHO Cancer Resolution and consistent with the principle of universal health coverage, which ensures access to optimal cancer care for all people because health is a basic human right. The time for action is now to reduce barriers and provide the highest possible quality cancer care to everyone regardless of circumstance, precondition or geographic location. The national actions and the policy recommendations in this paper set forth the vision of its authors for the future of global cancer control at the national level, where the WHO Cancer Resolution must be implemented if we are to reduce the cancer burden, avoid unnecessary suffering and save as many lives as possible. PMID:29464109

  10. Overview of the Altair Lunar Lander Thermal Control System Design and the Impacts of Global Access

    NASA Technical Reports Server (NTRS)

    Stephan, Ryan A.

    2011-01-01

    NASA's Constellation Program (CxP) was developed to successfully return humans to the Lunar surface prior to 2020. The CxP included several different project offices including Altair, which was planned to be the next generation Lunar Lander. The Altair missions were architected to be quite different than the Lunar missions accomplished during the Apollo era. These differences resulted in a significantly dissimilar Thermal Control System (TCS) design. The current paper will summarize the Altair mission architecture and the various operational phases associated with the planned mission. In addition, the derived thermal requirements and the TCS designed to meet these unique and challenging thermal requirements will be presented. During the past year, the design team has focused on developing a vehicle architecture capable of accessing the entire Lunar surface. Due to the widely varying Lunar thermal environment, this global access requirement resulted in major changes to the thermal control system architecture. These changes, and the rationale behind the changes, will be detailed throughout the current paper.

  11. Complex Cloud and Radiative Processes Unfolding at the Earth's Terminator: A Unique Perspective from the Proposed Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Davis, A. B.; Marshak, A.

    2018-02-01

    The Deep Space Gateway offers a unique vantage for Earth observation using reflected sunlight: day/night or night/day terminators slowly marching across the disc. It's an opportunity to improve our understanding of clouds at that key moment in their daily cycle.

  12. Deep Space Gateway Facilitates Exploration of Planetary Crusts: A Human/Robotic Exploration Design Reference Campaign to the Lunar Orientale Basin

    NASA Astrophysics Data System (ADS)

    Head, J. W.; Pieters, C. M.; Scott, D. R.

    2018-02-01

    We outline an Orientale Basin Human/Robotic Architecture that can be facilitated by a Deep Space Gateway International Science Operations Center (DSG-ISOC) (like McMurdo/Antarctica) to address fundamental scientific problems about the Moon and Mars.

  13. Gateway to Healthcare Careers for Vulnerable Students: A New Approach to the Teaching of Anatomy and Physiology

    ERIC Educational Resources Information Center

    DeCiccio, Albert; Kenny, Tammy; Lippacher, Linda; Flanary, Barry

    2011-01-01

    At Southern Vermont College (SVC) and at the nation's other colleges and universities, Anatomy and Physiology I (A&PI) is the gateway course into healthcare careers. Disturbingly, at SVC and elsewhere, many first-year students interested in healthcare careers do not succeed in this course. They withdraw from the course or the institution, or…

  14. Globalization and Health

    PubMed Central

    Martin, Greg

    2005-01-01

    This debut editorial of Globalization and Health introduces the journal, briefly delineating its goals and objectives and outlines its scope of subject matter. 'Open Access' publishing is expected to become an increasingly important format for peer reviewed academic journals and that Globalization and Health is 'Open Access' is appropriate. The rationale behind starting a journal dedicated to globalization and health is three fold: Firstly: Globalization is reshaping the social geography within which we might strive to create health or prevent disease. The determinants of health – be they a SARS virus or a predilection for fatty foods – have joined us in our global mobility. Driven by economic liberalization and changing technologies, the phenomenon of 'access' is likely to dominate to an increasing extent the unfolding experience of human disease and wellbeing. Secondly: Understanding globalization as a subject matter itself needs certain benchmarks and barometers of its successes and failings. Health is one such barometer. It is a marker of social infrastructure and social welfare and as such can be used to either sound an alarm or give a victory cheer as our interconnectedness hurts and heals the populations we serve. And lastly: In as much as globalization can have an effect on health, it is also true that health and disease has an effect on globalization as exemplified by the existence of quarantine laws and the devastating economic effects of the AIDS pandemic. A balanced view would propose that the effects of globalization on health (and health systems) are neither universally good nor bad, but rather context specific. If the dialogue pertaining to globalization is to be directed or biased in any direction, then it must be this: that we consider the poor first. PMID:15847699

  15. Deep Space Gateway Support of Lunar Surface Ops and Tele-Operational Transfer of Surface Assets to the Next Landing Site

    NASA Astrophysics Data System (ADS)

    Kring, D. A.

    2018-02-01

    The Deep Space Gateway can support astronauts on the lunar surface, providing them a departure and returning rendezvous point, a communication relay from the lunar farside to Earth, and a transfer point to Orion for return to Earth.

  16. The introduction of new vaccines into developing countries. IV: Global Access Strategies.

    PubMed

    Mahoney, Richard T; Krattiger, Anatole; Clemens, John D; Curtiss, Roy

    2007-05-16

    This paper offers a framework for managing a comprehensive Global Access Strategy for new vaccines in developing countries. It is aimed at strengthening the ability of public-sector entities to reach their goals. The Bill and Melinda Gates Foundation and The Rockefeller Foundation have been leaders in stimulating the creation of new organizations - public/private product development partnerships (PDPs) - that seek to accelerate vaccine development and distribution to meet the health needs of the world's poor. Case studies of two of these PDPs - the Salmonella Anti-pneumococcal Vaccine Program and the Pediatric Dengue Vaccine Initiative - examine development of such strategies. Relying on the application of innovation theory, the strategy leads to the identification of six Components of Innovation which cover all aspects of the vaccine innovation process. Appropriately modified, the proposed framework can be applied to the development and introduction of other products in developing countries including drugs, and nutritional and agricultural products.

  17. Wireless Distribution Systems To Support Medical Response to Disasters

    PubMed Central

    Arisoylu, Mustafa; Mishra, Rajesh; Rao, Ramesh; Lenert, Leslie A.

    2005-01-01

    We discuss the design of multi-hop access networks with multiple gateways that supports medical response to disasters. We examine and implement protocols to ensure high bandwidth, robust, self-healing and secure wireless multi-hop access networks for extreme conditions. Address management, path setup, gateway discovery and selection protocols are described. Future directions and plans are also considered. PMID:16779171

  18. Analysis of random drop for gateway congestion control. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Hashem, Emam Salaheddin

    1989-01-01

    Lately, the growing demand on the Internet has prompted the need for more effective congestion control policies. Currently No Gateway Policy is used to relieve and signal congestion, which leads to unfair service to the individual users and a degradation of overall network performance. Network simulation was used to illustrate the character of Internet congestion and its causes. A newly proposed gateway congestion control policy, called Random Drop, was considered as a promising solution to the pressing problem. Random Drop relieves resource congestion upon buffer overflow by choosing a random packet from the service queue to be dropped. The random choice should result in a drop distribution proportional to the bandwidth distribution among all contending TCP connections, thus applying the necessary fairness. Nonetheless, the simulation experiments demonstrate several shortcomings with this policy. Because Random Drop is a congestion control policy, which is not applied until congestion has already occurred, it usually results in a high drop rate that hurts too many connections including well-behaved ones. Even though the number of packets dropped is different from one connection to another depending on the buffer utilization upon overflow, the TCP recovery overhead is high enough to neutralize these differences, causing unfair congestion penalties. Besides, the drop distribution itself is an inaccurate representation of the average bandwidth distribution, missing much important information about the bandwidth utilization between buffer overflow events. A modification of Random Drop to do congestion avoidance by applying the policy early was also proposed. Early Random Drop has the advantage of avoiding the high drop rate of buffer overflow. The early application of the policy removes the pressure of congestion relief and allows more accurate signaling of congestion. To be used effectively, algorithms for the dynamic adjustment of the parameters of Early Random Drop

  19. Human resource solutions--the Gateway Paper proposed health reforms in Pakistan.

    PubMed

    Nishtar, Sania

    2006-12-01

    The existence of appropriate institutional and human resource capacity underpins the viability and sustainability of a health reform process within a country. Building human resource capacity within the health sector involves building the capacity of health service providers, health managers and administers as well as the stewards of health. Although capacity building is linked to a generic process closely linked to the broader economic, social and developmental context, it has specific health system connotations which should be the focus of a concerted effort. These include quantitative issues, in-effective deployment and brain-drain, qualitative considerations which stem from gaps in the quality of undergraduate as well as discrepancies in the content and format of training and absence of this in service of training health professionals and gaps in regulation. As one of the fundamental corner stones of health reform the Gateway Paper calls attention to the need to avert these issues with the development of a well-defined policy in human resource development as an entry point. This should be based on an analysis of the human resource need and should clearly define career structures for all categories of healthcare providers, and articulate the mechanisms of their effective deployment. Creating a conducive an rewarding environment, institutionalizing personnel management reform which go beyond personnel actions and set standards of performance, and develop appropriate incentives around this, would be critical. It would also be important to pay due attention to the content and format of training at an undergraduate level, at a postgraduate level and with reference to ongoing education and the allied roles of continuing medical education programs and accreditation of health systems educational institutions. The Gateway Paper also lays stress on effective regulation to curb the practice of quackery.

  20. Effects of Drake Passage on a strongly eddying global ocean

    NASA Astrophysics Data System (ADS)

    Viebahn, Jan; von der Heydt, Anna S.; Dijkstra, Henk A.

    2015-04-01

    During the past 65 Million (Ma) years, Earth's climate has undergone a major change from warm 'greenhouse' to colder 'icehouse' conditions with extensive ice sheets in the polar regions of both hemispheres. The Eocene-Oligocene (~34 Ma) and Oligocene-Miocene (~23 Ma) boundaries reflect major transitions in Cenozoic global climate change. Proposed mechanisms of these transitions include reorganization of ocean circulation due to critical gateway opening/deepening, changes in atmospheric CO2-concentration, and feedback mechanisms related to land-ice formation. Drake Passage (DP) is an intensively studied gateway because it plays a central role in closing the transport pathways of heat and chemicals in the ocean. The climate response to a closed DP has been explored with a variety of general circulation models, however, all of these models employ low model-grid resolutions such that the effects of subgrid-scale fluctuations ('eddies') are parameterized. We present results of the first high-resolution (0.1° horizontally) realistic global ocean model simulation with a closed DP in which the eddy field is largely resolved. The simulation extends over more than 200 years such that the strong transient adjustment process is passed and a near-equilibrium ocean state is reached. The effects of DP are diagnosed by comparing with both an open DP high-resolution control simulation (of same length) and corresponding low-resolution simulations. By focussing on the heat/tracer transports we demonstrate that the results are twofold: Considering spatially integrated transports the overall response to a closed DP is well captured by low-resolution simulations. However, looking at the actual spatial distributions drastic differences appear between far-scattered high-resolution and laminar-uniform low-resolution fields. We conclude that sparse and highly localized tracer proxy observations have to be interpreted carefully with the help of high-resolution model simulations.

  1. Access to medicines and distributive justice: breaching Doha's ethical threshold.

    PubMed

    Kiddell-Monroe, Rachel

    2014-08-01

    The global health crisis in non-communicable diseases (NCDs) reveals a deep global health inequity that lies at the heart of global justice concerns. Mirroring the HIV/AIDS epidemic, NCDs bring into stark relief once more the human consequences of trade policies that reinforce global inequities in treatment access. Recognising distributive justice issues in access to medicines for their populations, World Trade Organisation (WTO) members confirmed the primacy of access to medicines for all in trade and public health in the landmark Doha Declaration on the TRIPS Agreement and Public Health of 2001. © 2014 John Wiley & Sons Ltd.

  2. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2006-01-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs:(R)-Flurbiprofen, 90Yttrium-DOTA-huJ591; ABT-510, ACP-103, Ad5-FGF4, adalimumab, ademetionine, AG-7352, alemtuzumab, Amb a 1 ISS-DNA, anakinra, apaziquone, aprepitant, aripiprazole, atazanavir sulfate; BAL-8557, bevacizumab, BMS-188797, bortezomib, bosentan, brivudine; Calcipotriol/betamethasone dipropionate, cannabidiol, caspofungin acetate, catumaxomab, CERE-120, cetuximab, ciclesonide, cilomilast, cizolirtine citrate, Cypher, cystemustine; Dalbavancin, darifenacin hydrobromide, dasatinib, deferasirox, denosumab, desmoteplase, dihydrexidine, dimethyl fumarate, dutasteride, DW-166HC; Eculizumab, enfuvirtide, entecavir, epratuzumab, erlotinib hydrochloride, escitalopram oxalate, eszopiclone, etoricoxib, everolimus; Fallypride, febuxostat, fenretinide, fesoterodine, fingolimod hydrochloride; Gabapentin enacarbil, gefitinib; hMaxi-K, human papillomavirus vaccine, HYAL-CT1101; Imatinib mesylate, indiplon, inolimomab, ISAtx-247; J591; Lacosamide, landiolol, lasofoxifene tartrate, lestaurtinib, lidocaine/prilocaine, linezolid, lixivaptan, lonafarnib, lopinavir, lopinavir/ritonavir, lumiracoxib; Natalizumab, nesiritide; OC-108, omalizumab, onercept, OSC; Palifermin, palonosetron hydrochloride, parathyroid hormone (human recombinant), parecoxib sodium, PD-MAGE-3 vaccine, PEG-filgrastim, peginterferon alfa-2a, peginterferon alfa-2b, pegsunercept, pelitinib, pitavastatin calcium, plerixafor hydrochloride, posaconazole, prasterone sulfate, pregabalin; Ramelteon, ranelic acid distrontium salt, rasburicase, rosuvastatin calcium, rotigotine, RSD-1235, rufinamide, rupatadine fumarate; Sarizotan hydrochloride, SHL-749

  3. Gateways to clinical trials.

    PubMed

    Bayés, M; Rabasseda, X; Prous, J R

    2005-04-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity. prous.com. This issue focuses on the following selection of drugs: ABX-IL-8, Acclaim, adalimumab, AGI-1067, alagebrium chloride, alemtuzumab, Alequel, Androgel, anti-IL-12 MAb, AOD-9604, aripiprazole, atomoxetine hydrochloride; Biphasic insulin aspart, bosentan, botulinum toxin type B, bovine lactoferrin, brivudine; Cantuzumab mertansine, CB-1954, CDB-4124, CEA-TRICOM, choriogonadotropin alfa, cilansetron, CpG-10101, CpG-7909, CTL-102, CTL-102/CB-1954; DAC:GRF, darbepoetin alfa, davanat-1, decitabine, del-1 Genemedicine, dexanabinol, dextofisopam, dnaJP1, dronedarone hydrochloride, dutasteride; Ecogramostim, eletriptan, emtricitabine, EPI-hNE-4, eplerenone, eplivanserin fumarate, erlotinib hydrochloride, ertapenem sodium, escitalopram oxalate, esomeprazole magnesium, etoricoxib, ezetimibe; Falecalcitriol, fingolimod hydrochloride; Gepirone hydrochloride; HBV-ISS, HSV-2 theracine, human insulin; Imatinib mesylate, Indiplon, insulin glargine, ISAtx-247; L612 HuMAb, levodopa/carbidopa/entacapone, lidocaine/prilocaine, LL-2113AD, lucinactant, LY-156735; Meclinertant, metelimumab, morphine hydrochloride, morphine-6-glucuronide; Natalizumab, nimotuzumab, NX-1207, NYVAC-HIV C; Omalizumab, onercept, osanetant; PABA, palosuran sulfate, parathyroid hormone (human recombinant), parecoxib sodium, PBI-1402, PCK-3145, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b/ribavirin, pemetrexed disodium, pimecrolimus, PINC, pregabalin; Ramelteon, rasagiline mesilate, rasburicase, rimonabant hydrochloride, RO-0098557, rofecoxib, rosiglitazone maleate/metformin hydrochloride; Safinamide mesilate, SHL-749, sitaxsentan sodium, sparfosic acid, SprayGel, squalamine, St. John's Wort

  4. GATEWAY Report Brief: Evaluating Tunable LED Lighting in the Swedish Medical Behavioral Health Unit

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    Summary of a GATEWAY report evaluation of a tunable LED lighting system installed in the new Swedish Medical Behavioral Health Unit in Seattle that incorporates color-tunable luminaires in common areas, and uses advanced controls for dimming and color tuning, with the goal of providing a better environment for staff and patients. The report reviews the design of the tunable lighting system, summarizes two sets of measurements, and discusses the circadian, energy, and commissioning implications as well as lessons learned from the project.

  5. Using Instruments as Applied Science, Multipurpose Tools During Human Exploration: An XRD/XRF Demonstration Strategy for the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Bleacher, J. E.; Gendreau, K.; Arzoumanian, Z.; Young, K. E.; McAdam, A.

    2018-02-01

    Science instruments to be used during human exploration should be designed to serve as multipurpose tools that are of use throughout a mission. Here we discuss a multipurpose tool approach to using contact XRD/XRF onboard the Deep Space Gateway.

  6. The Gateway Paper--proposed health reforms in Pakistan--interface considerations.

    PubMed

    Nishtar, Sania

    2006-12-01

    The Gateway Paper recognizes three system interfaces as being critical to the delivery of healthcare within Pakistan. These include the federal/provincial interface, the provincial-district interface and the public-private interface. A number of gaps in each area have been highlighted. At the federal-provincial interface lack of provincial ownership of federal initiatives, gaps in provincial counterpart arrangements, ambiguities about federal and provincial roles and responsibilities, conflicts over sharing of resources and gaps in understanding provincial requirements and poor coordination have been articulated as core issues. It is envisaged that the development of a broad based mechanism to develop a consensus on national policy positions, incorporation of appropriate guidance from the provinces, giving provinces an active participatory role in decision-making, garnering their support and clearly demarcating roles and responsibilities will obviate some of these issues as would the institutionalization of a federal-provincial coordinating mechanism to review actions at both levels with regards to progress on meeting stipulating goals. At a district level poor governance, limited capacity within the system, lag in granting full district level financial and administrative autonomy, and lack of operational clarity in the rules of business have contributed to the challenge. This is compounded by inadvertent centralization of some functions within the district, which political and administrative decentralization has paradoxically created and impediments to harnessing the role of communities. The clear delineation of these issues provides a substrate, which need to be at the heart of strategic reform within the context of the recent devolution initiative. At the public-private interface the absence of locally established principles, legislative frameworks, policies and operational strategies have been contributing to the adhoc nature of public-private engagement within

  7. US Astronomers Access to SIMBAD in Strasbourg

    NASA Technical Reports Server (NTRS)

    Oliversen, Ronald (Technical Monitor); Eichhorn, Guenther

    2004-01-01

    During the last year the US SIMBAD Gateway Project continued to provide services like user registration to the US users of the SIMBAD database in France. Currently there are over 4500 US users registered. We also provided user support by answering questions from users and handling requests for lost passwords when still necessary. Even though almost all users now access SIMBAD without a password, based on hostnames/IP addresses, there are still some users that need individual passwords. We continued to maintain the mirror copy of the SIMBAD database on a server at SAO. This allows much faster access for the US users. During the past year we again moved this mirror to a faster server to improve access for the US users. We again supported a demonstration of the SIMBAD database at the meeting of the American Astronomical Society in January. We provided support for the demonstration activities at the SIMBAD booth. We paid part of the fee for the SIMBAD demonstration. We continued to improve the cross-linking between the SIMBAD project and the Astrophysics Data System. This cross-linking between these systems is very much appreciated by the users of both the SIMBAD database and the ADS Abstract Service. The mirror of the SIMBAD database at SA0 makes this connection faster for the US astronomers. We exchange information between the ADS and SIMBAD on a daily basis. During the last year we also installed a mirror copy of the Vizier system from the CDS, in addition to the SIMBAD mirror.

  8. Linking Educational Research Activities across Europe: A Review of the WIFO Gateway to Research on Education in Europe

    ERIC Educational Resources Information Center

    Manning, Sabine

    2007-01-01

    The WIFO Gateway to Research on Education in Europe (http://www.wifo-gate.org) is an Internet portal focusing on vocational education and training and human resource development. Launched 10 years ago by the Research Forum Education and Society (Wissenschaftsforum Bildung und Gesellschaft-WIFO) Berlin, it has developed in several stages in close…

  9. Gateway-Assisted Retransmission for Lightweight and Reliable IoT Communications.

    PubMed

    Chang, Hui-Ling; Wang, Cheng-Gang; Wu, Mong-Ting; Tsai, Meng-Hsun; Lin, Chia-Ying

    2016-09-22

    Message Queuing Telemetry Transport for Sensor Networks (MQTT-SN) and Constrained Application Protocol (CoAP) are two protocols supporting publish/subscribe models for IoT devices to publish messages to interested subscribers. Retransmission mechanisms are introduced to compensate for the lack of data reliability. If the device does not receive the acknowledgement (ACK) before retransmission timeout (RTO) expires, the device will retransmit data. Setting an appropriate RTO is important because the delay may be large or retransmission may be too frequent when the RTO is inappropriate. We propose a Gateway-assisted CoAP (GaCoAP) to dynamically compute RTO for devices. Simulation models are proposed to investigate the performance of GaCoAP compared with four other methods. The experiment results show that GaCoAP is more suitable for IoT devices.

  10. A multisite gateway-based toolkit for targeted gene expression and hairpin RNA silencing in tomato fruits.

    PubMed

    Estornell, Leandro Hueso; Orzáez, Diego; López-Peña, Lucas; Pineda, Benito; Antón, María Teresa; Moreno, Vicente; Granell, Antonio

    2009-04-01

    A collection of fruit promoters, reporter genes and protein tags has been constructed in a triple-gateway format, a recombination-based cloning system that facilitates the tandem assembly of three DNA fragments into plant expression vectors. The new pENFRUIT collection includes, among others, the classical tomato-ripening promoters E8 and 2A11 and a set of six new tomato promoters. The new promoter activities were characterized in both transient assays and stable transgenic plants. The range of expression of the new promoters comprises strong (PNH, PLI), medium (PLE, PFF, PHD) and weak (PSN) promoters driving gene expression preferentially in the fruit, and covering a wide range of tissues and developmental stages. Together, a total of 78 possible combinations for the expression of a gene of interest in the fruit, plus a set of five reporters for new promoter analysis, was made available in the current collection. Moreover, the pENFRUIT promoter collection is adaptable to hairpin RNA strategies aimed at tissue/organ-specific gene silencing with only an additional cloning step. The pENFRUIT toolkit broadens the spectrum of promoter activities available for fruit biotechnology and fundamental research, and bypasses technical difficulties of current ligase-dependent cloning techniques in the construction of fruit expression cassettes. The pENFRUIT vector collection is available for the research community in a plasmid repository, facilitating its accessibility.

  11. NERIES: Seismic Data Gateways and User Composed Datasets Metadata Management

    NASA Astrophysics Data System (ADS)

    Spinuso, Alessandro; Trani, Luca; Kamb, Linus; Frobert, Laurent

    2010-05-01

    One of the NERIES EC project main objectives is to establish and improve the networking of seismic waveform data exchange and access among four main data centers in Europe: INGV, GFZ, ORFEUS and IPGP. Besides the implementation of the data backbone, several investigations and developments have been conducted in order to offer to the users the data available from this network, either programmatically or interactively. One of the challenges is to understand how to enable users` activities such as discovering, aggregating, describing and sharing datasets to obtain a decrease in the replication of similar data queries towards the network, exempting the data centers to guess and create useful pre-packed products. We`ve started to transfer this task more and more towards the users community, where the users` composed data products could be extensively re-used. The main link to the data is represented by a centralized webservice (SeismoLink) acting like a single access point to the whole data network. Users can download either waveform data or seismic station inventories directly from their own software routines by connecting to this webservice, which routes the request to the data centers. The provenance of the data is maintained and transferred to the users in the form of URIs, that identify the dataset and implicitly refer to the data provider. SeismoLink, combined with other webservices (eg EMSC-QuakeML earthquakes catalog service), is used from a community gateway such as the NERIES web portal (http://www.seismicportal.eu). Here the user interacts with a map based portlet which allows the dynamic composition of a data product, binding seismic event`s parameters with a set of seismic stations. The requested data is collected by the back-end processes of the portal, preserved and offered to the user in a personal data cart, where metadata can be generated interactively on-demand. The metadata, expressed in RDF, can also be remotely ingested. They offer rating

  12. "To Trust in My Root and to Take That to Go Forward": Supporting College Access for Immigrant Youth in the Global City

    ERIC Educational Resources Information Center

    Jaffe-Walter, Reva; Lee, Stacey J.

    2011-01-01

    Increasing numbers of immigrant youth are coming of age within global cities that are characterized by growing inequalities and few opportunities for social mobility. These youth face numerous educational obstacles that complicate college and labor market access. This article draws from an ethnographic study of public high schools serving…

  13. Fair Access to Higher Education: Global Perspectives

    ERIC Educational Resources Information Center

    Mountford-Zimdars, Anna, Ed.; Sabbagh, Daniel, Ed.; Post, David, Ed.

    2015-01-01

    What does "fairness" mean internationally in terms of access to higher education? Increased competition for places in elite universities has prompted a worldwide discussion regarding the fairness of student admission policies. Despite budget cuts from governments--and increasing costs for students--competition is fierce at the most…

  14. Multifunctional Interface Facility for Receiving and Processing Planetary Surface Materials for Science Investigation and Resource Evaluation at the Deep Space Gateway

    NASA Astrophysics Data System (ADS)

    Sibille, L.; Mantovani, J. G.; Townsend, I. I.; Mueller, R. P.

    2018-02-01

    The concepts describe hardware and instrumentation for the study of planetary surface materials at the Deep Space Gateway as a progressive evolution of capabilities for eliminating the need for special handling and Planetary Protection (PP) protocols inside the habitats.

  15. D1/D5 Receptors and Histone Deacetylation Mediate the Gateway Effect of LTP in Hippocampal Dentate Gyrus

    ERIC Educational Resources Information Center

    Huang, Yan-You; Lavine, Amir; Kandel, Denise B.; Yin, Deqi; Colnaghi, Luca; Drisaldi, Bettina; Kandel, Eric R.

    2014-01-01

    The dentate gyrus (DG) of the hippocampus is critical for spatial memory and is also thought to be involved in the formation of drug-related associative memory. Here, we attempt to test an aspect of the Gateway Hypothesis, by studying the effect of consecutive exposure to nicotine and cocaine on long-term synaptic potentiation (LTP) in the DG. We…

  16. System Access | High-Performance Computing | NREL

    Science.gov Websites

    ) systems. Photo of man looking at a large computer monitor with a colorful, visual display of data. System secure shell gateway (SSH) or virtual private network (VPN). User Accounts Request a user account

  17. An Open-Access Modeled Passenger Flow Matrix for the Global Air Network in 2010

    PubMed Central

    Huang, Zhuojie; Wu, Xiao; Garcia, Andres J.; Fik, Timothy J.; Tatem, Andrew J.

    2013-01-01

    The expanding global air network provides rapid and wide-reaching connections accelerating both domestic and international travel. To understand human movement patterns on the network and their socioeconomic, environmental and epidemiological implications, information on passenger flow is required. However, comprehensive data on global passenger flow remain difficult and expensive to obtain, prompting researchers to rely on scheduled flight seat capacity data or simple models of flow. This study describes the construction of an open-access modeled passenger flow matrix for all airports with a host city-population of more than 100,000 and within two transfers of air travel from various publicly available air travel datasets. Data on network characteristics, city population, and local area GDP amongst others are utilized as covariates in a spatial interaction framework to predict the air transportation flows between airports. Training datasets based on information from various transportation organizations in the United States, Canada and the European Union were assembled. A log-linear model controlling the random effects on origin, destination and the airport hierarchy was then built to predict passenger flows on the network, and compared to the results produced using previously published models. Validation analyses showed that the model presented here produced improved predictive power and accuracy compared to previously published models, yielding the highest successful prediction rate at the global scale. Based on this model, passenger flows between 1,491 airports on 644,406 unique routes were estimated in the prediction dataset. The airport node characteristics and estimated passenger flows are freely available as part of the Vector-Borne Disease Airline Importation Risk (VBD-Air) project at: www.vbd-air.com/data. PMID:23691194

  18. An open-access modeled passenger flow matrix for the global air network in 2010.

    PubMed

    Huang, Zhuojie; Wu, Xiao; Garcia, Andres J; Fik, Timothy J; Tatem, Andrew J

    2013-01-01

    The expanding global air network provides rapid and wide-reaching connections accelerating both domestic and international travel. To understand human movement patterns on the network and their socioeconomic, environmental and epidemiological implications, information on passenger flow is required. However, comprehensive data on global passenger flow remain difficult and expensive to obtain, prompting researchers to rely on scheduled flight seat capacity data or simple models of flow. This study describes the construction of an open-access modeled passenger flow matrix for all airports with a host city-population of more than 100,000 and within two transfers of air travel from various publicly available air travel datasets. Data on network characteristics, city population, and local area GDP amongst others are utilized as covariates in a spatial interaction framework to predict the air transportation flows between airports. Training datasets based on information from various transportation organizations in the United States, Canada and the European Union were assembled. A log-linear model controlling the random effects on origin, destination and the airport hierarchy was then built to predict passenger flows on the network, and compared to the results produced using previously published models. Validation analyses showed that the model presented here produced improved predictive power and accuracy compared to previously published models, yielding the highest successful prediction rate at the global scale. Based on this model, passenger flows between 1,491 airports on 644,406 unique routes were estimated in the prediction dataset. The airport node characteristics and estimated passenger flows are freely available as part of the Vector-Borne Disease Airline Importation Risk (VBD-Air) project at: www.vbd-air.com/data.

  19. Systematic cloning of an ORFeome using the Gateway system.

    PubMed

    Matsuyama, Akihisa; Yoshida, Minoru

    2009-01-01

    With the completion of the genome projects, there are increasing demands on the experimental systems that enable to exploit the entire set of protein-coding open reading frames (ORFs), viz. ORFeome, en masse. Systematic proteomic studies based on cloned ORFeomes are called "reverse proteomics," and have been launched in many organisms in recent years. Cloning of an ORFeome is such an attractive way for comprehensive understanding of biological phenomena, but is a challenging and daunting task. However, recent advances in techniques for DNA cloning using site-specific recombination and for high-throughput experimental techniques have made it feasible to clone an ORFeome with the minimum of exertion. The Gateway system is one of such the approaches, employing the recombination reaction of the bacteriophage lambda. Combining traditional DNA manipulation methods with modern technique of the recombination-based cloning system, it is possible to clone an ORFeome of an organism on an individual level.

  20. Intelligent Document Gateway: A Service System Case Study and Analysis

    NASA Astrophysics Data System (ADS)

    Krishna, Vikas; Lelescu, Ana

    In today's fast paced world, it is necessary to process business ­documents expediently, accurately, and diligently. In other words, processing has to be fast, errors must be prevented (or caught and corrected quickly), and documents cannot be lost or misplaced. The failure to meet these criteria, depending on the type and purpose of the documents, can have serious business, legal, or safety consequences. In this paper, we evaluated a B2B order placement service system that allows clients to place orders for products and services over a network. We describe the order placement service before and after deploying the Intelligent Document Gateway (IDG), a document-centric business process automation technology from IBM Research. Using service science perspective and service systems frameworks, we provide an analysis of how IDG improved the value proposition for both the service providers and service clients.

  1. Gateway-Assisted Retransmission for Lightweight and Reliable IoT Communications

    PubMed Central

    Chang, Hui-Ling; Wang, Cheng-Gang; Wu, Mong-Ting; Tsai, Meng-Hsun; Lin, Chia-Ying

    2016-01-01

    Message Queuing Telemetry Transport for Sensor Networks (MQTT-SN) and Constrained Application Protocol (CoAP) are two protocols supporting publish/subscribe models for IoT devices to publish messages to interested subscribers. Retransmission mechanisms are introduced to compensate for the lack of data reliability. If the device does not receive the acknowledgement (ACK) before retransmission timeout (RTO) expires, the device will retransmit data. Setting an appropriate RTO is important because the delay may be large or retransmission may be too frequent when the RTO is inappropriate. We propose a Gateway-assisted CoAP (GaCoAP) to dynamically compute RTO for devices. Simulation models are proposed to investigate the performance of GaCoAP compared with four other methods. The experiment results show that GaCoAP is more suitable for IoT devices. PMID:27669243

  2. Design of an Open Smart Energy Gateway for Smart Meter Data Management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Page, Janie; McParland, Chuck; Piette, Mary Ann

    With the widespread deployment of electronic interval meters, commonly known as smart meters, came the promise of real-time data on electric energy consumption. Recognizing an opportunity to provide consumers access to their near real-time energy consumption data directly from their installed smart meter, we designed a mechanism for capturing those data for consumer use via an open smart energy gateway (OpenSEG). By design, OpenSEG provides a clearly defined boundary for equipment and data ownership. OpenSEG is an open-source data management platform to enable better data management of smart meter data. Effectively, it is an information architecture designed to work withmore » the ZigBee Smart Energy Profile 1.x (SEP 1.x). It was specifically designed to reduce cyber-security risks and provide secure information directly from smart meters to consumers in near real time, using display devices already owned by the consumers. OpenSEG stores 48 hours of recent consumption data in a circular cache using a format consistent with commonly available archived (not real-time) consumption data such as Green Button, which is based on the Energy Services Provider Interface (ESPI) data standard. It consists of a common XML format for energy usage information and a data exchange protocol to facilitate automated data transfer upon utility customer authorization. Included in the design is an application program interface by which users can acquire data from OpenSEG for further post processing. A sample data display application is included in the initial software product. The data display application demonstrates that OpenSEG can help electricity use data to be retrieved from a smart meter and ported to a wide variety of user-owned devices such as cell phones or a user-selected database. This system can be used for homes, multi-family buildings, or small commercial buildings in California.« less

  3. Global Health Observatory (GHO)

    MedlinePlus

    ... monitoring partnerships, including the Countdown to 2030 and academic institutions. – Access the portal Global Observatory on Health ... global situation and trends highlights, using core indicators, database views, major publications and links to relevant web ...

  4. Milankovitch forcing and role of Indonesian Gateway on middle Miocene climate and carbon cycle: New perspective from the South China Sea, equatorial West Pacific and East Indian Ocean

    NASA Astrophysics Data System (ADS)

    Holbourn, A.; Kuhnt, W.; Schulz, M.

    2003-04-01

    The enigmatic long-term positive carbon isotope excursion ("Monterey excursion") in the middle Miocene exhibits an apparent 400 ky cyclicity (long eccentricity cycle of the Milankovitch frequency band). Similar isotope excursion are known from the mid-Cretaceous and may be a characteristic feature of a greenhouse world with extreme warm climate, high sealevel, and a dominantly zonal circulation pattern in the world ocean. This period of extreme warmth (the mid-Miocene climate optimum) ended between 14.2 and 13.8 Ma, when a significant increase in deep-water oxygen isotopic values occurred that was related to the growth of the East Antarctic ice sheet. Plate tectonic movements between Australia and SE Asia, ultimately leading to the closure of the deep water gateway connecting the Indian and Pacific Oceans, started prior to this paleoceanographic change. We used benthic deep water oxygen and carbon isotope curves in combination with new age models at critical locations along the northern margin of the Indonesian Gateway (South China Sea, ODP Site 1146), at the western end of the gateway (NW Australian margin, ODP Site 761) and at the eastern end of the gateway (Ontong Java Plateau, ODP Site 806) to investigate the frequency and amplitude of deep water isotope fluctuations during the middle Miocene. High resolution sediment color reflectance data, benthic carbon isotopes and foraminiferal assemblages are used as proxies of deep-water ventilation and carbon flux. Our results indicate Milankovitch forcing on virtually all proxies and a change from eccentricity to precession driven cyclicity at approximately 15 Ma. Our data reveal increased carbon flux and a restricted deep water exchange between the Pacific Ocean and Indian Ocean through the Indonesian Gateway during the middle Miocene climate optimum. After 13.6 Ma, the decrease in d13C was strongest at Site 806, indicating a marked change in the deep-water circulation of the equatorial West Pacific and a switch to a

  5. Bridges or Barriers? Conceptualization of the Role of Multiple Identity Gateway Groups in Intergroup Relations.

    PubMed

    Levy, Aharon; Saguy, Tamar; Halperin, Eran; van Zomeren, Martijn

    2017-01-01

    The modern era of globalization has been accompanied by a massive growth in interconnections between groups, and has led to the sharing of multiple identities by individuals and groups. Following these developments, research has focused on the issue of multiple identities, and has shed important light on how individuals who hold these complex forms of identity feel and behave, and on the reactions they elicit from members of other groups. However, the potential of groups with such multiple identities (e.g., biracials, immigrants, etc.) to affect the intergroup relations between the groups that represent the respective sources of the different identities (e.g., Blacks and Whites, country of origin and country of residence, etc.) has not been examined to date. Accordingly, in this paper, we first systematically explore the potential of groups in which people identify with multiple social categories, or groups that are perceived as such by others, to play a role in intergroup dynamics. Next, we offer a theoretical framework outlining what functions groups of people with shared multiple identities may serve (as bridges or barriers ) by proposing how their presence may facilitate or deteriorate intergroup relations. Finally, we present recent empirical research examining how groups of people with shared multiple identities can act as gateways and bridge the cleft between two separate groups that represent the respective sources of their different identities, and discuss the theoretical and practical implications for the field of intergroup relations.

  6. Bridges or Barriers? Conceptualization of the Role of Multiple Identity Gateway Groups in Intergroup Relations

    PubMed Central

    Levy, Aharon; Saguy, Tamar; Halperin, Eran; van Zomeren, Martijn

    2017-01-01

    The modern era of globalization has been accompanied by a massive growth in interconnections between groups, and has led to the sharing of multiple identities by individuals and groups. Following these developments, research has focused on the issue of multiple identities, and has shed important light on how individuals who hold these complex forms of identity feel and behave, and on the reactions they elicit from members of other groups. However, the potential of groups with such multiple identities (e.g., biracials, immigrants, etc.) to affect the intergroup relations between the groups that represent the respective sources of the different identities (e.g., Blacks and Whites, country of origin and country of residence, etc.) has not been examined to date. Accordingly, in this paper, we first systematically explore the potential of groups in which people identify with multiple social categories, or groups that are perceived as such by others, to play a role in intergroup dynamics. Next, we offer a theoretical framework outlining what functions groups of people with shared multiple identities may serve (as bridges or barriers) by proposing how their presence may facilitate or deteriorate intergroup relations. Finally, we present recent empirical research examining how groups of people with shared multiple identities can act as gateways and bridge the cleft between two separate groups that represent the respective sources of their different identities, and discuss the theoretical and practical implications for the field of intergroup relations. PMID:28706501

  7. Gateway Effects: Why the Cited Evidence Does Not Support Their Existence for Low-Risk Tobacco Products (and What Evidence Would).

    PubMed

    Phillips, Carl V

    2015-05-21

    It is often claimed that low-risk drugs still create harm because of "gateway effects", in which they cause the use of a high-risk alternative. Such claims are popular among opponents of tobacco harm reduction, claiming that low-risk tobacco products (e.g., e-cigarettes, smokeless tobacco) cause people to start smoking, sometimes backed by empirical studies that ostensibly support the claim. However, these studies consistently ignore the obvious alternative causal pathways, particularly that observed associations might represent causation in the opposite direction (smoking causes people to seek low-risk alternatives) or confounding (the same individual characteristics increase the chance of using any tobacco product). Due to these complications, any useful analysis must deal with simultaneity and confounding by common cause. In practice, existing analyses seem almost as if they were designed to provide teaching examples about drawing simplistic and unsupported causal conclusions from observed associations. The present analysis examines what evidence and research strategies would be needed to empirically detect such a gateway effect, if there were one, explaining key methodological concepts including causation and confounding, examining the logic of the claim, identifying potentially useful data, and debunking common fallacies on both sides of the argument, as well as presenting an extended example of proper empirical testing. The analysis demonstrates that none of the empirical studies to date that are purported to show a gateway effect from tobacco harm reduction products actually does so. The observations and approaches can be generalized to other cases where observed association of individual characteristics in cross-sectional data could result from any of several causal relationships.

  8. Gateway Effects: Why the Cited Evidence Does Not Support Their Existence for Low-Risk Tobacco Products (and What Evidence Would)

    PubMed Central

    Phillips, Carl V.

    2015-01-01

    It is often claimed that low-risk drugs still create harm because of “gateway effects”, in which they cause the use of a high-risk alternative. Such claims are popular among opponents of tobacco harm reduction, claiming that low-risk tobacco products (e.g., e-cigarettes, smokeless tobacco) cause people to start smoking, sometimes backed by empirical studies that ostensibly support the claim. However, these studies consistently ignore the obvious alternative causal pathways, particularly that observed associations might represent causation in the opposite direction (smoking causes people to seek low-risk alternatives) or confounding (the same individual characteristics increase the chance of using any tobacco product). Due to these complications, any useful analysis must deal with simultaneity and confounding by common cause. In practice, existing analyses seem almost as if they were designed to provide teaching examples about drawing simplistic and unsupported causal conclusions from observed associations. The present analysis examines what evidence and research strategies would be needed to empirically detect such a gateway effect, if there were one, explaining key methodological concepts including causation and confounding, examining the logic of the claim, identifying potentially useful data, and debunking common fallacies on both sides of the argument, as well as presenting an extended example of proper empirical testing. The analysis demonstrates that none of the empirical studies to date that are purported to show a gateway effect from tobacco harm reduction products actually does so. The observations and approaches can be generalized to other cases where observed association of individual characteristics in cross-sectional data could result from any of several causal relationships. PMID:26006122

  9. OneGeology - improving access to geoscience globally

    NASA Astrophysics Data System (ADS)

    Jackson, Ian; Asch, Kristine; Tellez-Arenas, Agnès.; Komac, Marko; Demicheli, Luca

    2010-05-01

    The OneGeology concept originated in early 2006. With the potential stimulus of the International Year of Planet Earth (IYPE) very much in mind, the challenge was: could we use IYPE to begin the creation of an interoperable digital geological dataset of the planet? Fourteen months later on the concept was unanimously endorsed by 83 representatives of the international geoscience community at a meeting in Brighton, UK, and goals were set to for a global launch at the 33rd IGC in Oslo in August 2008. The goals that the Brighton meeting agreed for OneGeology were deceptively simple. They were to: • improve the accessibility of geological map data • exchange know-how and skills so that all nations could participate • accelerate interoperability in the geosciences and the take up of a new "standard" (GeoSciML) At the time of writing (January 2010) there are 113 countries participating in OneGeology, more than 40 of which are serving data using a web map portal and protocols, registries and technology to "harvest" and serve data from around the world. An essential part of the development of OneGeology has been the exchange of know-how and provision of guidance and support so that any geological survey can participate and serve their data. The team have also moved forward and raised the profile of a crucial data model and interoperability standard - GeoSciML, which will allow geoscience data to be shared across the globe. OneGeology is coordinated through a two-part "hub" - a Secretariat based at the British Geological Survey (BGS), and the portal technology and servers provided by the French geological survey (BRGM). The "hub" is guided and supported by two international groups - the Operational Management Group (OMG) and the Technical Working Group (TWG). A Steering Group to provide strategic guidance for OneGeology and comprising geological survey directors representing the six continents was formed at the end of 2008. The Steering Group are now looking at

  10. Ovarian developmental variation in the primitively eusocial wasp Ropalidia marginata suggests a gateway to worker ontogeny and the evolution of sociality.

    PubMed

    Shukla, Shantanu; Chandran, Swarnalatha; Gadagkar, Raghavendra

    2013-01-15

    Social insects are characterized by reproductive caste differentiation of colony members into one or a small number of fertile queens and a large number of sterile workers. The evolutionary origin and maintenance of such sterile workers remains an enduring puzzle in insect sociobiology. Here, we studied ovarian development in over 600 freshly eclosed, isolated, virgin female Ropalidia marginata wasps, maintained in the laboratory. The wasps differed greatly both in the time taken to develop their ovaries and in the magnitude of ovarian development despite having similar access to resources. All females started with no ovarian development at day zero, and the percentage of individuals with at least one oocyte at any stage of development increased gradually across age, reached 100% at 100 days and decreased slightly thereafter. Approximately 40% of the females failed to develop ovaries within the average ecological lifespan of the species. Age, body size and adult feeding rate, when considered together, were the most important factors governing ovarian development. We suggest that such flexibility and variation in the potential and timing of reproductive development may physiologically predispose females to accept worker roles and thus provide a gateway to worker ontogeny and the evolution of sociality.

  11. The EarthServer project: Exploiting Identity Federations, Science Gateways and Social and Mobile Clients for Big Earth Data Analysis

    NASA Astrophysics Data System (ADS)

    Barbera, Roberto; Bruno, Riccardo; Calanducci, Antonio; Messina, Antonio; Pappalardo, Marco; Passaro, Gianluca

    2013-04-01

    The EarthServer project (www.earthserver.eu), funded by the European Commission under its Seventh Framework Program, aims at establishing open access and ad-hoc analytics on extreme-size Earth Science data, based on and extending leading-edge Array Database technology. The core idea is to use database query languages as client/server interface to achieve barrier-free "mix & match" access to multi-source, any-size, multi-dimensional space-time data -- in short: "Big Earth Data Analytics" - based on the open standards of the Open Geospatial Consortium Web Coverage Processing Service (OGC WCPS) and the W3C XQuery. EarthServer combines both, thereby achieving a tight data/metadata integration. Further, the rasdaman Array Database System (www.rasdaman.com) is extended with further space-time coverage data types. On server side, highly effective optimizations - such as parallel and distributed query processing - ensure scalability to Exabyte volumes. Six Lighthouse Applications are being established in EarthServer, each of which poses distinct challenges on Earth Data Analytics: Cryospheric Science, Airborne Science, Atmospheric Science, Geology, Oceanography, and Planetary Science. Altogether, they cover all Earth Science domains; the Planetary Science use case has been added to challenge concepts and standards in non-standard environments. In addition, EarthLook (maintained by Jacobs University) showcases use of OGC standards in 1D through 5D use cases. In this contribution we will report on the first applications integrated in the EarthServer Science Gateway and on the clients for mobile appliances developed to access them. We will also show how federated and social identity services can allow Big Earth Data Providers to expose their data in a distributed environment keeping a strict and fine-grained control on user authentication and authorisation. The degree of fulfilment of the EarthServer implementation with the recommendations made in the recent TERENA Study on

  12. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2006-03-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 131I-labetuzumab; Abacavir sulfate, abatacept, adalimumab, ademetionine, adjuvanted influenza vaccine, alefacept, alemtuzumab, amlodipine, amphotericin B, anakinra, aripiprazole, aspirin, axitinib; Betamethasone dipropionate, bevacizumab, biphasic insulin aspart, bortezomib, bosentan, botulinum toxin type B, BQ-123; Calcium folinate, canertinib dihydrochloride, carboplatin, carmustine, cetirizine hydrochloride, cetuximab, cholecalciferol, ciclesonide, ciclosporin, cinacalcet hydrochloride, cisplatin, clarithromycin, clofazimine, cold-adapted influenza vaccine trivalent, CpG-7909; Darbepoetin alfa, darifenacin hydrobromide, DB-289, desloratadine, Dexamet, dicycloverine hydrochloride, dimethyl fumarate, docetaxel, dolastatin 10, drospirenone, drospirenone/estradiol, duloxetine hydrochloride; Ecogramostim, edotecarin, efaproxiral sodium, enalapril maleate, epoetin beta, epoprostenol sodium, epratuzumab, erlotinib hydrochloride, escitalopram oxalate, estradiol, etanercept; Fluconazole, fludarabine phosphate, fluorouracil; Gefitinib, gemcitabine, Ghrelin (human), glibenclamide, glimepiride, GTI-2040; Haloperidol, human insulin, hydrocortisone probutate; Imatinib mesylate, indisulam, influenza vaccine, inhaled insulin, insulin aspart, insulin glulisine, insulin lispro, irinotecan, ispronicline; Lamivudine, lamivudine/zidovudine/abacavir sulfate, lapatinib, letrozole, levocetirizine, lomustine, lonafarnib, lumiracoxib;Magnesium sulfate, MD-1100, melphalan, metformin hydrochloride, methotrexate, metoclopramide hydrochloride, mitiglinide calcium hydrate, monophosphoryl lipid A, montelukast sodium, motexafin gadolinium

  13. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2005-10-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: (-)-Epigallocatechin gallate, (Z)-4-hydroxytamoxifen; Ad.muIFN-beta AD-237, adalimumab, adefovir dipivoxil, agalsidase alfa, alemtuzumab, almotriptan, ALVAC vCP1452, alvimopan hydrate, ambrisentan, anakinra, anti-IFN-gamma MAb; Bimatoprost, BMS-188797, BMS-214662, bortezomib, bosentan, bovine lactoferrin; Caffeine, canertinib dihydrochloride, canfosfamide hydrochloride, cannabidiol, caspofungin acetate, cetuximab, cH36, ChimeriVax-JE, ciclesonide, cilansetron, cinacalcet hydrochloride, clopidogrel, CpG-7909, Cypher; Daptomycin, darbepoetin alfa, darifenacin hydrobromide, decitabine, denufosol tetrasodium, Dexamet, diindolemethane, drotrecogin alfa (activated), duloxetine hydrochloride, DX-9065a; E-7010, edaravone, efalizumab, eicosapentaenoic acid/docosahexaenoic acid, elacridar, eletriptan, emtricitabine, epratuzumab, erlotinib hydrochloride, ertapenem sodium, eszopiclone, everolimus, ezetimibe; Fludarabine, fondaparinux sodium; gamma-Hydroxybutyrate sodium, gavestinel sodium, gefitinib, granisetron-Biochronomer; Human Albumin, human insulin; Imatinib mesylate, indiplon, interleukin-2 XL, isatoribine, ISS-1018, i.v. gamma-globulin, ivabradine hydrochloride, ixabepilone; Lanthanum carbonate, L-arginine hydrochloride, liposomal doxorubicin, LY-450139; Magnesium sulfate, melatonin, motexafin gadolinium, mycophenolic acid sodium salt; Natalizumab, nesiritide, niacin/lovastatin; OGX-011, olmesartan medoxomil, omalizumab, ospemifene; PACAP38, panitumumab, parathyroid hormone (human recombinant), parecoxib sodium, patupilone, pegfilgrastim, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b

  14. Flood risk and insurance loss potential in the Thames Gateway

    NASA Astrophysics Data System (ADS)

    Eldridge, J.; Horn, D.

    2009-04-01

    The Thames Gateway, currently Europe's largest regeneration project, is an area of redevelopment located in the South East of England, with Government plans to create up to 160,000 new homes and 180,000 new jobs by 2016. Although the new development is intended to contribute £12bn annually to the economy, the potential flood risk is high, with much of the area situated on Thames tidal floodplain and vulnerable to both storm surges and peak river flows. This poses significant hazard to those inhabiting the area and has raised concern amongst the UK insurance industry, who would be liable for significant financial claims if a large flood event were to occur, particularly with respect to the number of new homes and businesses being built in flood risk areas. Flood risk and the potential damage to both lives and assets in vulnerable areas have gained substantial recognition, in light of recent flooding events, from both governmental agencies and in the public's awareness of flood hazard. This has resulted in a change in UK policy with planning policy for flood risk (PPS25, Planning Policy Statement 25) adopting a more strategic approach to development, as well as a new Flooding and Water Bill which is due for consultation in 2009. The Government and the Association of British Insurers, who represent the UK insurance industry, have also recently changed their Statement of Principles which guides provision of flood insurance in the future. This PhD research project aims to quantify flood risk in the Thames Gateway area with a view to evaluating the insurance loss potential under different insurance and planning scenarios. Using current sources of inundation extent, and incorporating varying insurance penetration rates and degrees of adoption of planning policy and guidance, it focuses on estimating flood risk under these different scenarios. This presentation introduces the development of the project and the theory and methodology which will be used to address the

  15. Registered access: a 'Triple-A' approach.

    PubMed

    Dyke, Stephanie O M; Kirby, Emily; Shabani, Mahsa; Thorogood, Adrian; Kato, Kazuto; Knoppers, Bartha M

    2016-12-01

    We propose a standard model for a novel data access tier - registered access - to facilitate access to data that cannot be published in open access archives owing to ethical and legal risk. Based on an analysis of applicable research ethics and other legal and administrative frameworks, we discuss the general characteristics of this Registered Access Model, which would comprise a three-stage approval process: Authentication, Attestation and Authorization. We are piloting registered access with the Demonstration Projects of the Global Alliance for Genomics and Health for which it may provide a suitable mechanism for access to certain data types and to different types of data users.

  16. Accessibility of near-Earth asteroids, 1990

    NASA Technical Reports Server (NTRS)

    Hulkower, Neal D.; Child, Jack B.

    1991-01-01

    Previous research which analyzed the accessibility of all known near-Earth asteroids is updated. Since then, many new near-Earth asteroids have been discovered, and 1928 DB, the most accessible asteroid at that time, has been recovered. Many of these recently discovered near-Earth asteroids have promising orbital characteristics. In addition to accessibility (as defined by minimum global delta v), ideal rendezvous opportunities are identified.

  17. 77 FR 1759 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ..., which Items have been prepared by the Exchange. The Commission is publishing this notice to solicit... Customer Gateway (``CCG'') that accesses the equity trading systems that it shares with its affiliates... increasing connectivity costs, including additional costs based on gateway software and hardware enhancements...

  18. 78 FR 69040 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-18

    ... a Food Safety Education and Training Materials Database. The Database is a centralized gateway to... creating previously available education materials), (2) provide a central gateway to access the education materials, (3) create a systematic and efficient method of collecting data from USDA grantees, and (4...

  19. Formulary availability and regulatory barriers to accessibility of opioids for cancer pain in India: a report from the Global Opioid Policy Initiative (GOPI).

    PubMed

    Cleary, J; Simha, N; Panieri, A; Scholten, W; Radbruch, L; Torode, J; Cherny, N I

    2013-12-01

    India is the world's largest democracy with control of opioids divided between the national and state governments. While the global consumption of opioids has increased, the consumption has not increased at the same rate. This is the first comprehensive study of opioid availability and accessibility for cancer patients in India. Data are reported on the availability and accessibility of opioids for the management of cancer pain in 24 of the states that make up India and the Administrative area around Delhi. About 1061 million of the nation's 1189 million people (89%) are covered by this survey. Without exception, opioid availability continues to be low throughout all of India. Even when opioids are on formulary, they are often unavailable. Access is significantly impaired by widespread over-regulation that continues to be pervasive across the nation.

  20. Integrating the ODI-PPA scientific gateway with the QuickReduce pipeline for on-demand processing

    NASA Astrophysics Data System (ADS)

    Young, Michael D.; Kotulla, Ralf; Gopu, Arvind; Liu, Wilson

    2014-07-01

    As imaging systems improve, the size of astronomical data has continued to grow, making the transfer and processing of data a significant burden. To solve this problem for the WIYN Observatory One Degree Imager (ODI), we developed the ODI-Portal, Pipeline, and Archive (ODI-PPA) science gateway, integrating the data archive, data reduction pipelines, and a user portal. In this paper, we discuss the integration of the QuickReduce (QR) pipeline into PPA's Tier 2 processing framework. QR is a set of parallelized, stand-alone Python routines accessible to all users, and operators who can create master calibration products and produce standardized calibrated data, with a short turn-around time. Upon completion, the data are ingested into the archive and portal, and made available to authorized users. Quality metrics and diagnostic plots are generated and presented via the portal for operator approval and user perusal. Additionally, users can tailor the calibration process to their specific science objective(s) by selecting custom datasets, applying preferred master calibrations or generating their own, and selecting pipeline options. Submission of a QuickReduce job initiates data staging, pipeline execution, and ingestion of output data products all while allowing the user to monitor the process status, and to download or further process/analyze the output within the portal. User-generated data products are placed into a private user-space within the portal. ODI-PPA leverages cyberinfrastructure at Indiana University including the Big Red II supercomputer, the Scholarly Data Archive tape system and the Data Capacitor shared file system.