A system is presented that may simplify the study of accessory cell requirements for CTL generation. Cortisone resistant (CR) thymocytes containing alloreactive CTL precursors do not respond to allogeneic tumor cells unless non-T accessory cells are added to culture. In ...
Energy Citations Database
... The electrical response activity of single nerve cells in the accessory nucleus of the superior olive was studied. Stimulus ...
DTIC Science & Technology
Adult (8-week-old) SJL mice reach a relatively low degree of tolerance when injected with aggregate free rabbit ..gamma..-globulin (RGG). To analyze this phenomenon, we first examined indirect plaque-forming responses (PFC) in terms of participation of accessory and thymus-derived cells. Double transfer experiments were used; accessory ...
NK cells are cytotoxic lymphocytes that are most efficient at fulfilling their functions after a phase of priming provided by cytokines and/or accessory cells. Although type I IFNs are known to be important in this process, it remains unclear whether they act directly on NK cells or indirectly on ...
PubMed
In vitro primary antibody responses to limiting concentrations of trinitrophenyl (TNP)-Ficoll were shown to be T cell dependent, requiring the cooperation of T helper (TH) cells, B cells, and accessory cells. Under these conditions, TH cells derived ...
Pancreatic islet transplantation is a therapeutic option to replace destroyed ? cells in autoimmune diabetes. Islets are transplanted into the liver via the portal vein; however, inflammation, the required immunosuppression, and lack of vasculature decrease early islet viability and function. Therefore, the use of accessory therapy and ...
... through earphones to the two ears of anesthetized cats, and the electrical response activity of single nerve cells in the accessory nucleus of the ...
Mitogen-stimulated human T cell activation is absolutely dependent on the participation of a nonresponding accessory cell. In populations of human peripheral blood mononuclear cells, monocytes function as the requisite accessory cells. The possibility that cultured ...
PubMed Central
Antigen-induced T cell proliferation requires T cell interaction with antigen in the context of MHC I region-compatible accessory cells. The resulting activation and proliferation of T cells involves the production and utilization of several lymphokines or interleukins. ...
Disclosed are compositions of bone accessory cells and methods for their preparation and use. Bone accessory cells are cells which are not hematopoietic and which can reconstitute the expression of bone proteins by human bone cells and support ex vivo exp...
National Technical Information Service (NTIS)
Macrophages: important accessory cells for reproductive function Paula E. Cohen,* Kayoko Nishimura functions, can be considered as essential accessory cells for normal reproductive functioning. J. Leukoc of the bone marrow, monocytes, macrophages, osteoclasts, and microglia. Cells of the ...
E-print Network
In plants, gametes, along with accessory cells, are formed by the haploid gametophytes through a series of mitotic divisions, cell specification and differentiation events. How the cells in the female gametophyte of flowering plants differentiate into gametes (the egg and central cell) and ...
The induction of innate immune responses by toll-like receptor (TLR) agonists is the subject of intense investigation. In large part, this reflects the potential of such compounds to be effective vaccine adjuvants. For that reason, we analyzed the activation of innate cells in swine by TLR7 and TLR8 agonists. These agonists activated porcine NK cells by ...
Access to the article is free, however registration and sign-in are required. The viral accessory protein Vif is required for the production of infectious virions by cells that do not normally permit viral replication to take place. In their Perspective, KewalRamani and Coffin discuss an exciting cluster of recent ...
NSDL National Science Digital Library
is initially started, the battery typically powers all accessories. The gasoline engine only starts if the battery needs to be charged or the accessories require more power...
DOE Alternative Fuels and Advanced Vehicles Data Center
NK cell development requires IL-15, which is "trans-presented" to IL-15R?? on NK cells by IL-15R? on other cells. In this study, we report that different levels of IL-15 trans-presentation are required for different NK cell developmental events to reach full maturation ...
Accessory cells, which include glia and other cell types that develop in close association with neurons, have been shown to play key roles in regulating neuron development. However, the underlying molecular and cellular mechanisms remain poorly understood. A particularly intimate association between accessory ...
This program was directed toward near-term automotive accessory optimization and toward evaluation of accessory systems for advanced Stirling and turbine automotive and truck propulsion engines. The objective was to define, evaluate and develop automotive...
The program objective is to evolve and define an accessory drive system that will minimize system power consumption of driven accessories on an internal combustion engine in a passenger automobile. The initial three program phases established concept feas...
Progress in a program for optimizing automotive accessory systems to achieve greater vehicle fuel economy and improved accessory performance is reported. The major technical accomplishments during this reporting period were: all candidate advanced air con...
This is the eighth quarterly technical progress report for a program in which the objective is to evolve and define an accessory drive system that will minimize system power consumption of driven accessories on an internal combustion engine in a passenger...
The objective of this program is to evolve and define an accessory drive system that will minimize system power consumption of driven accessories on an internal combustion engine in a passenger automobile. The initial program phases established concept fe...
Progress is reported for a program whose objective is to evolve and define an accessory drive system that will minimize system power consumption of driven accessories on an internal combustion engine in a passenger automobile. Although the primary goal is...
The objective of this program was to define, evaluate, and develop automotive accessory systems to minimize engine power consumption and significantly improve fuel economy. Standard accessory equipment includes air conditioning, power steering alternator,...
... Abstract : Sperm cells collected from mammals by electroejaculation or with an ... by secretions and fluids from the accessory glands, cell debris, and ...
... other accessories for the characterization of chemically processed ceramics, glasses ... CHEMICAL ANALYSIS, PROCESSING, CELLS, COUPLING ...
The present invention provides a number of accessory gland proteins from Drosophila. The invention also provides an accessory gland protein which is toxic to insect cells and can be used to kill or inhibit the development of insects. Methods of controllin...
Different �professional� antigen-presenting cells (APC) have unique characteristics that favor or restrict presentation of microbial antigens to T cells, depending on the organism. Cryptococcus neoformans is a pathogenic yeast that presents unique challenges to APC, including its large size, its rigid cell wall, and its ability to ...
The present study used cocultures of clonally derived B and T cells, together with an antigen reactive with the membrane Ig of the clonal B cells, to address the issue of B-cell differentiation requirements. The B cells were CH12.LX, an in vitro grown subclone of a murine ...
Plant germ cells develop in specialized haploid structures, termed gametophytes. The female gametophyte patterns of flowering plants are diverse, with often unknown adaptive value. Here we present the Arabidopsis fiona mutant, which forms a female gametophyte that is structurally and functionally reminiscent of a phylogenetic distant female gametophyte. The respective changes ...
Access to the article is free, however registration and sign-in are required. Guanosine triphosphatases (GTPases) are critical regulatory molecules in cells. In this issue, Scheffzek et al. report the structure of the key GTPase Ras complexed with its GAP, an accessory molecule necessary for efficient catalysis. In his Perspective, ...
This is the second of two volumes that document a study on the reduction of automotive accessory power requirements. The volume presents the technical aspects of the total funded effort for five program phases including; conceptual design, preliminary des...
Immunosuppressive effects of low levels of ultraviolet B (UVB) radiation on cutaneous immune responses have been attributed to deleterious effects of UVB radiation on epidermal Langerhans cells (LC). To determine how UVB radiation modulates LC function we examined the effect of in vitro UVB exposure on LC accessory cell activity and ...
... 46 XIII Changes in Accessory Pigments in Comparison With Chlorophyll a as Effected by Growth of Algae in Monochromatic and White Illumination ...
deals with problems relating to instruments and accessories required for the .... early in the year and appeared so promising that the Clarke Thomson ...
NASA Website
The Field Reversed Mirror Reactor is composed of a horizontal linear chain of cells, each of which requires neutral beam injection. Blanket replacement is achieved by lifting one complete cell module from the reactor and replacing it with a preassembled and tested identical module. Ioffe bar connectors eliminate redundant bus bars. ...
The mitochondrial replication machinery in human cells includes the DNA polymerase gamma holoenzyme and the TWINKLE helicase. Together, these two factors form a processive replication machinery, a replisome, which can use duplex DNA as template to synthesize long stretches of single-stranded DNA. We here address the importance of the smaller, accessory B ...
THE TRIFUNCTIONAL ANTIBODY (TRAB) CATUMAXOMAB IS CHARACTERIZED BY A UNIQUE ABILITY TO BIND THREE DIFFERENT CELL TYPES: tumor cells; T-cells; and accessory cells. It binds to epithelial cell adhesion molecule (EpCAM) on tumor cells, the CD3 antigen on ...
The trifunctional antibody (trAb) catumaxomab is characterized by a unique ability to bind three different cell types: tumor cells; T-cells; and accessory cells. It binds to epithelial cell adhesion molecule (EpCAM) on tumor cells, the CD3 antigen on ...
... Rats, chronically implanted with microwires in the dorsal accessory olive and arrays of Purkinje cells in the paravermal cerebellum will be ...
Neurogenic genes, including Notch and Delta, are thought to play important roles in regulating cell�cell interactions required for Drosophila sense organ development. To define the requirement of the neurogenic gene neuralized (neu) in this process, two independent neu alleles were used to generate mutant clones. We find that neu is ...
The regulation of osteocalcin gene expression by 1,25-dihydroxyvitamin D3 is mediated by the vitamin D receptor and a cis-acting DNA response element that has been identified within the 5' region of the osteocalcin promoter. In this report, we show that vitamin D receptors derived from nuclear extracts of mammalian cells bind directly to this cis-acting element in vitro and do ...
Fe2+ acted as an accessorial factor for many cellular enzymatic reactions is very important for seaweed growth and development, but the Fe2+ requirement in nori had not been seen, Porphyra yezoensis cells were separated enzymatically and cultured in a series of sterilized seawater media containing various concentrations of Fe2+. The ...
NASA Astrophysics Data System (ADS)
Resting T lymphocytes that have recognized antigen bound to a major histocompatibility complex molecule with the T-cell receptor require costimulatory signals through accessory receptors, including CD2, CD4, CD8, and CD28, for their clonal growth and expression of their functional repertoires. Absence of costimulation, in contrast, can ...
... kinase C activation by phorbol myristate acetate (PMA) results in T-cell proliferation that is independent of both accessory cells and activation of the ...
... etiology of sporadic and hereditary breast tumors. ... Cells studied were MCF-7 (breast cancer cells). ... 8 complexes were separated from cell lysates ...
The accessory cell (AC) signals involved in the activation of resting guinea pig T lymphocytes stimulated with mitogen (PHA), or the calcium ionophore, ionomycin (Ion) were examined. Activation of T cells was assessed by cell cycle analysis after acridine orange staining and /sup 3/H-thymidine incorporation. ...
Three periplasmic N-acetylmuramoyl-L-alanine amidases are critical for hydrolysis of septal peptidoglycan, which enables cell separation. The amidases cleave the amide bond between the lactyl group of muramic acid and the amino group of L-alanine to release a peptide moiety. Cell division amidases remain largely uncharacterized because suitable substrates ...
This specification defines the objectives, criteria, and configuration and establishes the requirements for performance, design, test, and qualification of the accessory drive subsystem (ADS) for the prototype model supersonic transport airplane. Differen...
The objective of this study program is to minimize automotive accessory horsepower consumption, and thereby maximize overall vehicle fuel economy, by utilizing continuously variable speed drives or auxiliary power units (APUs) in a standard passenger auto...
The report fulfills the requirements of FDA Contract 223-77-5037, Task Order No. 3 to research and describe the common characteristics of endoscopes and endoscopic accessories, identify the hazards and performance problems associated with their use, and r...
... mechanisms similar to those of the limb and accessory sex organs to pattern penile postnatal morphogenesis and differentiation and ... the embryonic precursor of both the penis and accessory sex organs. T...
NBII National Biological Information Infrastructure
An orbital and entry tracking accessory or attachment is described which can be mounted on a globe to provide a rapid means of determining range requirements for entry vehicles returning from any orbit to any desired landing site with reasonable accuracy....
An orbital and entry tracking accessory or attachment is arranged to be mounted on a globe to provide a rapid means of determining range requirements for entry vehicles returning from any orbit to any desired landing site with reasonable accuracy. The dev...
...special accessories shall be included in the application for a grant of equipment authorization or retained in the verification...form other than paper, such as on a computer disk or over the Internet, the information required by this section may be...
Code of Federal Regulations, 2010
The role of accessory cells (AC) in the initiation of mitogen-induced T cell proliferation was examined by comparing the effect of intact macrophages (M phi) with that of 4-..beta..-phorbol 12-myristate 13-acetate (PMA). In high-density cultures, purified guinea pig T cells failed to proliferate in response to ...
... estradiol-treatment has also been found in different accessory sex organs of the rabbit [20] and rat [11]. Many ... the weights and histology of the epididymis and sex accessory organs of sexually immatur...
The mechanism for genetic errors and genomic instability in breast cancer cells have not been fully delineated. Defects in DNA polymerase delta and its accessory proteins could contribute to the molecular etiology of breast cancer. DNA polymerase delta an...
The goal of this investigation is to test the hypothesis that estrogen agonists and antagonists promote differential transcriptional activity of the estrogen receptor (ER) by altering accessory protein interactions. We have shown that one or more ER-assoc...
The accessory Sec (SecA2/Y2) systems of streptococci and staphylococci are dedicated to the transport of large serine-rich repeat (SRR) glycoproteins to the bacterial cell surface. The means by which the glycosylated preproteins are selectively recognized by the accessory Sec system have not been fully characterized. In Streptococcus ...
The human immunodeficiency virus type 1 (HIV-1) accessory protein Vpu enhances virus particle release by counteracting a host factor that retains virions at the surfaces of infected cells. It was recently demonstrated that cellular protein BST-2/CD317/Tetherin restricts HIV-1 release in a Vpu-dependent manner. Calcium-modulating cyclophilin ligand (CAML) ...
ARFs are small GTPases that regulate vesicular trafficking, cell shape, and movement. ARFs are subject to extensive regulation by a large number of accessory proteins. The many different accessory proteins are likely specialized to regulate ARF signaling during particular processes. ARNO/cytohesin 2 is an ARF-activating protein that ...
This program was directed toward near-term automotive accessory optimization and toward evaluation of accessory systems for advanced Stirling and turbine automotive and truck propulsion engines. The objective was to define, evaluate and develop automotive accessory systems to minimize engine power consumption and significantly improve ...
... Other Accessories Steps to reduce exposure to radiofrequency energy If there is a risk from being exposed to radiofrequency energy (RF) from cell phones--and at this point ...
MedlinePLUS
... The hypothesis that sex- Wehner, 1986; McIntyre et ... immune functions INFLUENCE OF SEXUAL BEHAVIOR (Hochman ... func- tion of accessory cells ...
The ultrastructure of the ovary of the amphilinidean cestode Amphilina japonica Goto & Ishii, 1936 from the body-cavity of the American sturgeon Acipenser transmontanus Richardson is described using transmission electron microscopy. The characters of the ovary of Amphilina japonica are different from those of all other cestodes. The most important difference is in the nature of the ...
